pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of High Dose Vitamin C On Outcome in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Reperfusion Injury
Interventions: DRUG: Ascorbic Acid|OTHER: 5 % Dextrose Water or Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunct Inversion for Lower Pole Stone
Status: COMPLETED
Conditions: Kidney Stone
Interventions: PROCEDURE: Inversion|PROCEDURE: Shock Wave Lithotripsy|DRUG: Hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney Transplantation
Status: RECRUITING
Conditions: Ischemia Reperfusion Injury|Delayed Graft Function
Interventions: DRUG: Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CLBR001 and SWI019 in Patients With Relapsed / Refractory B-cell Malignancies
Status: COMPLETED
Conditions: Relapsed/Refractory B-cell Lymphomas|Diffuse Large B Cell Lymphoma (DLBCL)|Follicular Lymphoma (FL)|Chronic Lymphocytic Leukemia (CLL)|Marginal Zone Lymphoma (MZL)|Mantle Cell Lymphoma|Small Lymphocytic Lymphoma (SLL)|Primary Mediastinal Large B Cell Lymphoma|Transformed Follicular Lymphoma|Waldenstrom Macroglobulinemia|Lymphoplasmacytic Lymphoma|Burkitt Lymphoma
Interventions: COMBINATION_PRODUCT: CLBR001 and SWI019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Status: RECRUITING
Conditions: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Interventions: BIOLOGICAL: Pegozafermin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trials of Pulsed Sonic Balloon Dilatation Catheter and Pulsed Sonic Generater
Status: UNKNOWN
Conditions: Coronary Calcified Disease
Interventions: DEVICE: Pulsed Sonic Balloon Dilatation Catheter and Pulsed Sonic Generater
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of MEDI-528 in Adults
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: MEDI528 30 mg|BIOLOGICAL: MEDI528 100 mg|BIOLOGICAL: MEDI528 300 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Seroquel SR in Combination With an Antidepressant in Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Quetiapine SR|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic Study of Red Yeast Rice Capsule Compared to Lovastatin Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: LipoCol Forte capsules|DRUG: Lovastatin Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Bevacizumab, Gemcitabine and Carboplatin in Newly Diagnosed Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Bevacizumab|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation Dosimetry s in Patients With Orofacial Pain
Status: NOT_YET_RECRUITING
Conditions: Orofacial Pain|Tension-Type Headache
Interventions: RADIATION: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of CellCept (Mycophenolate Mofetil) and Reduced Corticosteroids in Controlling Symptoms of Myasthenia Gravis
Status: COMPLETED
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: mycophenolate mofetil (CellCept)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Adalimumab in Patients Who Showed an Unsatisfactory Response to Etanercept
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Adalimumab every other week|DRUG: Adalimumab Every Week
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Complications to Diabetic Autonomic Neuropathy With Vagus Nerve Stimulation
Status: COMPLETED
Conditions: Gastrointestinal Dysfunction|Diabetes Mellitus
Interventions: DEVICE: Non-invasive transcutaneous vagus nerve stimulation|DEVICE: Sham vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Transcranial Magnetic Stimulation (TMS) With Paired Associative Stimulation (PAS) for the Treatment of Food Addiction in Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: A multi-channel deep TMS device with an H-coil (Brainsway Ltd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Estrogen Impact on Overactive Bladder Syndrome: Female Pelvic Floor Microbiomes and Antimicrobial Peptides
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: conjugated estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Δ9-THC to Treat Chronic Abdominal Pain
Status: COMPLETED
Conditions: Cannabinoid|Tetrahydrocannabinol|Chronic Pancreatitis|Abdominal Pain
Interventions: DRUG: Namisol|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Malignant Adrenal Gland Pheochromocytoma|Malignant Paraganglioma|Metastatic Adrenal Gland Pheochromocytoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenvatinib|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aromatherapy on Postoperative Pain: Randomized Clinical Trial
Status: RECRUITING
Conditions: Acute Pain|Perioperative/Postoperative Complications|CAM|Nurse's Role
Interventions: OTHER: essencial oil of lavandula angustifolia|OTHER: grape seed vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influenza Vaccine Trial in HIV Uninfected Pregnant Women
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza vaccine|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Finasteride Treatment of Severe Nodulocystic Acne
Status: COMPLETED
Conditions: NODULOCYSTIC ACNE
Interventions: DRUG: Finasteride 23.5 mg tablets|DRUG: Finasteride 33.5 mg tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery
Status: COMPLETED
Conditions: Gastric Bypass Surgery|Obesity
Interventions: OTHER: Liquid Meal|OTHER: Solid Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Heart-specific Mortality in the Presence of Competing Risks Among Patients With Non-metastatic Gastric Adenocarcinoma Undergoing Resection and Chemotherapy
Status: COMPLETED
Conditions: Long-term Heart-specific Mortality in the Presence of Competing Risks Among Patients With Gastric Adenocarcinoma Undergoing Resection and Chemotherapy
Interventions: PROCEDURE: Resection and chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acetazolamide Trial in Normal Pressure Hydrocephalus
Status: RECRUITING
Conditions: Idiopathic Normal Pressure Hydrocephalus (INPH)
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in DNA Samples From Patients With Chronic Lymphocytic Leukemia Previously Treated With Fludarabine-Based Therapy
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA analysis|GENETIC: gene expression analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: medical chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erectile Recovery After Robotic-Assisted Laparoscopic Prostatectomy
Status: UNKNOWN
Conditions: Erectile Dysfunction|Prostate Cancer
Interventions: DRUG: Sildenafil 25 MG Oral Tablet|DRUG: Pentoxifylline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate in Treating Patients With Advanced Cancer and Kidney Failure
Status: COMPLETED
Conditions: Malignant Neoplasm|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: imatinib mesylate|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study for Patients Who Had Not Met Criteria for Discontinuation in Previous Sponsored Belinostat Trials
Status: COMPLETED
Conditions: Solid Tumor|Hematological Malignancies
Interventions: DRUG: Belinostat|DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Causal Impact of Online Social Media on Physical Activity: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Media-assisted fitness program|BEHAVIORAL: Social network-assisted fitness program|BEHAVIORAL: Basic fitness program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery
Status: COMPLETED
Conditions: Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal Circulation
Interventions: PROCEDURE: Coronary Artery Bypass Graft (CABG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hospital Visit as Opportunity for Prevention and Engagement for HIV-Infected Drug Users
Status: COMPLETED
Conditions: HIV|AIDS|Substance Abuse|Inpatient
Interventions: BEHAVIORAL: Patient Navigation (PN) Group|BEHAVIORAL: Patient Navigator Plus Contingency Management (PN+CM) Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Assessment, Patient Treatment Satisfaction and Quality-of-Life in Insulin-Naive Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine (HOE901)/NPH Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive BRAF-MEK Inhibitor Therapy for Advanced BRAF Mutant Melanoma
Status: RECRUITING
Conditions: Melanoma (Skin)|Skin Cancer|Skin Melanoma|Skin Carcinoma
Interventions: DRUG: Encorafenib|DRUG: Binimetinib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Function and Uterine Fibroids
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DEVICE: Brachial artery catheter|DRUG: Acetylcholine|DRUG: Nitroprusside|DRUG: Norepinephrine|DRUG: Nitroprusside and phenylephrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Observational Study to Evaluate the Safety and Efficacy of Cetuximab in Combination With Platinum-based Chemotherapy in the First-line Treatment of Recurrent or Metastatic Squamous Cell Carcinoma of Head and Neck
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: Cetuximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pancreatitis CytoSorbents (CytoSorb®) Inflammatory Cytokine Removal
Status: UNKNOWN
Conditions: Pancreatitis, Acute|SIRS
Interventions: DEVICE: CytoSorb
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Teclistamab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An A/B Dose Escalation Study of AbGn-7 Alone and With FOLFOX7 Treatment in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor of Epithelial Origin|Gastric Cancer
Interventions: DRUG: AbGn-7|DRUG: AbGn-7
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stress Ball on COPD Patients Receiving Noninvasive Mechanical Ventilation Support
Status: NOT_YET_RECRUITING
Conditions: Mechanical Ventilation Pressure High|COPD
Interventions: OTHER: stress ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAR650984 (Isatuximab), Lenalidomide, and Dexamethasone in Combination in RRMM Patients
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: DRUG: isatuximab SAR650984|DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Pharmacokinetic Profiles of Losartan With DW1029M
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Losartan 50mg|DRUG: DW1029M 1200mg and Losartan 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Skin Safety Study to Evaluate the Irritation Potential in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: M518101|DRUG: M518101 Vehicle|OTHER: sodium lauryl sulfate|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Comparative Study of Error Rates Between ELLIPTA® Dry Powder Inhaler (DPI) and Other DPIs
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Relvar ELLIPTA|DEVICE: Symbicort TURBUHALER|DEVICE: Seretide DISKUS|DEVICE: Spiriva HANDIHALER|DEVICE: BREEZHALER|DEVICE: Incruse ELLIPTA|DEVICE: Anoro ELLIPTA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of D9421-C 9 mg and 15 mg Versus Placebo in Japanese Patients With Active Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: D9421-C, 9mg|DRUG: D9421-C, 15mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacology Study of CHF1535 pMDI 50/6 µg Versus The Free Combination In Asthmatic Children 5-11 Years Old
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF1535 pMDI + AC Plus|DRUG: BDP + AC Plus|DRUG: Formoterol + AC Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine With Rituximab, Vincristine, and Cyclophosphamide in Refractory Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Hodgkin Disease|Lymphoma, Non-Hodgkin
Interventions: DRUG: Azacitidine with rituximab, vincristine, and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythrocyte Glutamine Level Relation to Pulmonary Hypertension Risk in Beta Thalassemia Major Children
Status: COMPLETED
Conditions: Thalassemia in Children|Pulmonary Hypertension|Hemolysis
Interventions: DIAGNOSTIC_TEST: blood sample|DIAGNOSTIC_TEST: Tricuspid regurge velocity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endophthalmitis Post Intravitreal Injections
Status: RECRUITING
Conditions: Endophthalmitis
Interventions: PROCEDURE: Tap and Inject (TAI)|PROCEDURE: Pars Plana Vitrectomy (PPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Tadalafil in Patients With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: BPH With Other Lower Urinary Tract Symptoms
Interventions: DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Detecting Chemosensitivity and Predicting Treatmemt Efficacy With CTCs in mNPC
Status: RECRUITING
Conditions: Circulating Tumor Cell|Nasopharyngeal Carcinoma|Distant Metastases.Clinical|Effects of Chemotherapy
Interventions: DRUG: cisplatin-based chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Controlled Trial of InterVapor® in France - The TARGET Trial
Status: NOT_YET_RECRUITING
Conditions: Emphysema
Interventions: DEVICE: Treatment plus Optimal Medical Therapy|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Platelet-Leukocyte Aggregates in Pneumonia With Ticagrelor
Status: COMPLETED
Conditions: Pneumonia|Community Acquired Pneumonia|Hospital Acquired Pneumonia|Acute Lung Injury
Interventions: DRUG: ticagrelor|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Types of Fluoride Varnish in Preventing Early Childhood Caries
Status: UNKNOWN
Conditions: Early Childhood Caries
Interventions: OTHER: NaF vanish|OTHER: NaF-TCP|OTHER: NaF-CPP-ACP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pain Relief in Symptomatic Bone Metastases With Adjuvant Hyperthermia MR Guided HIFU
Status: RECRUITING
Conditions: Bone Metastases|Radiotherapy|Pain|MRI
Interventions: DEVICE: HIFU-MRI guided
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Simvastatin|DRUG: Rosuvastatin|DRUG: MGL-3196
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-up to 5 Years
Status: COMPLETED
Conditions: Eczema|Asthma|Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: pentoxifylline|DRUG: alpha-Tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Denileukin Diftitox Plus High-Dose IL-2 for Patients With Metastatic Renal Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: denileukin diftitox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ETGBD in Surgically Unfit Patients With Both Choledocholithiasis and Cholecystolithiasis
Status: COMPLETED
Conditions: Efficacy
Interventions: PROCEDURE: ERCP(Endoscopic retrograde choangiopancreatography), ETGBD(endoscopic transpapillary gallbladder drainage)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Different Toothbrushes and Hygiene Regimen
Status: UNKNOWN
Conditions: Dental Plaque|Halitosis
Interventions: OTHER: Total 12 regimen|OTHER: Toothbrushing alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)
Status: NOT_YET_RECRUITING
Conditions: Burnout|Burnout, Professional|Positive Affect|Depression|Anxiety|Compassion Fatigue|Job Stress
Interventions: BEHAVIORAL: FOREST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minimal Effective Concentration (EC90) of Ropivacaine
Status: COMPLETED
Conditions: Anesthesia, Conduction|Ropivacaine|Dexamethasone|Axillary Brachial Plexus Block
Interventions: DRUG: Intravenous dexamethasone|DRUG: Intravenous saline|DRUG: Perineural ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Disease|Mesothelioma|Metastases|Lung Cancer|Breast Cancer
Interventions: GENETIC: iCasp9M28z T cell infusions|DRUG: cyclophosphamide|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study
Status: RECRUITING
Conditions: Congenital Heart Disease in Children|Post-cardiac Surgery|Malnutrition, Infant
Interventions: DIETARY_SUPPLEMENT: Energy- Protein Enriched Nutritional Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Church as a Bridge to Deliver Health Resources Via Telehealth
Status: COMPLETED
Conditions: Obesity|Diet, Food, and Nutrition|Church|Healthcare Disparities|Minority Health|Mobile Health|Telehealth|Community-based Participatory Research|Primary Health Care|Weight Loss Programs|Health Behavior
Interventions: BEHAVIORAL: Church Bridge Project
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Fosfomycin Trometamol Per os in the Treatment of Documented Male Urinary Tract Infections With ESBL-producing Enterobacteriaceae With ESBL Producing Enterobacteriaceae and Resistance Associated With Fluoroquinolones and Cotrimoxazole (FOSF'HOM)
Status: UNKNOWN
Conditions: Urinary Tract Infections
Interventions: DRUG: Fosfomycin Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Modalities for Severe Odontogenic Infections Using Rapid, Target Enriched Multiplex PCR (TEM- PCR) by Diatherix
Status: COMPLETED
Conditions: Odontogenic Deep Space Neck Infection
Interventions: DIAGNOSTIC_TEST: Target Enriched Multiplex PCR (TEM- PCR)|DIAGNOSTIC_TEST: Microbial culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Stand Out in Class: Reducing Sitting Time in the Classroom Environment
Status: COMPLETED
Conditions: Sedentary Behavior|Child Behavior|Physical Activity|Obesity|Health Behavior
Interventions: DEVICE: Ergotron LearnFit Sit-Stand desk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy of Artemether-Lumefantrine Tablets in African Infants and Children With Uncomplicated P. Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Swab Site and Sample Collector on Testing Sensitivity for COVID-19 Virus in Symptomatic Individuals
Status: COMPLETED
Conditions: Infections, Respiratory|Fever|Cough
Interventions: DIAGNOSTIC_TEST: Testing Sensitivity for SARS-CoV-2 Virus in Symptomatic Individuals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Root End Filling Material Type and the Application of Bone Graft on Healing of Periapical Tissues After Endodontic Microsurgery (A Clinical Randomized Controlled Trial)
Status: COMPLETED
Conditions: Periapical Diseases|Periapical Cyst
Interventions: PROCEDURE: Apical microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Relative Bioavailability (BA) and Effect of Food on TAK-831 Tablet Formulations in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-831 T2|DRUG: TAK-831 T3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Direct Anti HCV Drugs in the Treatment of SARS-COV-2 (COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Sofosbuvir 400 MG plus Daclatasvir 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of DWP14012 in Patients With Erosive Gastroesophageal Reflux Disease (Phase 3)
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: DWP14012 40mg|DRUG: DWP14012 40mg placebo|DRUG: Esomeprazole 40mg|DRUG: Esomeprazole 40mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RoActemra/Actemra (Tocilizumab) Given Subcutaneously in Combination With Traditional DMARDs in Patients With Moderate to Severe Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab 162 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure
Status: RECRUITING
Conditions: Lyme Disease|Post-Treatment Lyme Disease|Chronic Lyme Disease|Tick-Borne Infections|Pregnancy Complications|Child Development
Interventions: OTHER: Neurodevelopmental assessments and follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin to Treat Obesity in Children With Insulin Resistance
Status: COMPLETED
Conditions: Hyperinsulinemia|Obesity
Interventions: DRUG: Metformin HCL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BOTOX Injections in Prevention of Migraine in Adult Participants With Episodic Migraine
Status: ACTIVE_NOT_RECRUITING
Conditions: Episodic Migraine
Interventions: DRUG: BOTOX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Home Full Blood Count (FBC) Telemonitoring Device for Chemotherapy Patient
Status: COMPLETED
Conditions: Cancer
Interventions: DEVICE: Home Telemonitoring System (The Zodiac, Philips Health care)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
Status: NOT_YET_RECRUITING
Conditions: Primary Aldosteronism|Resistant Hypertension|Secondary Hypertension|Hyperaldosteronism|Mineralocorticoid Excess|Hypertension
Interventions: OTHER: Best Practice Advisory Computerized Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: NORMAL HUMAN IMMUNOGLOBULINS (IVIG) IN PATIENTS AGED 75 YEARS AND OVER, COVID-19 WITH SEVERE ACUTE RESPIRATORY FAILURE
Status: UNKNOWN
Conditions: Sars-CoV2
Interventions: DRUG: IgIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE IMMUNOLOGICAL EFFECTS AND METABOLIC TOLERANCE OF LIPID INFUSION IN PATIENTS WITH CIRRHOSIS.
Status: COMPLETED
Conditions: Alcoholic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Soybean based lipid emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurofeedback Intervention in Children With Autism Spectrum Disorder (ASD)
Status: UNKNOWN
Conditions: Neurofeedback|Autistic Disorder|Autism Spectrum Disorder|Neurodevelopmental Disorders
Interventions: DEVICE: Neurofeedback Equipment (Cygnet) by BEE Medic GmbH Technologies, Baden-Wurttemberg, Germany.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Levobupivacaine and Bupivacaine for Nerve Block During Pediatric Primary Cleft Palate Surgery
Status: COMPLETED
Conditions: Recovery After Cleft Palate Surgery
Interventions: DRUG: Levobupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine for the Treatment for Alcohol Use Disorder in the ED
Status: WITHDRAWN
Conditions: Alcohol Use Disorder
Interventions: DRUG: Ketamine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Omegas 3 and 6 on Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Naltrexone|DRUG: PUFAs|DRUG: Placebo|DRUG: Naltrexone + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Rheumatic Heart Disease|Cardiopulmonary Bypass|Immunotherapy
Interventions: DRUG: Thymosin Alpha1|OTHER: Blank Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Micronutrient Supplementation (MMS) Iron Dose Acceptability Crossover Trial
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Multiple Micronutrient Supplements with 30 mg of elemental iron|DIETARY_SUPPLEMENT: Multiple Micronutrient Supplements with 45 mg of elemental iron|DIETARY_SUPPLEMENT: Multiple Micronutrient Supplements with 60 mg of elemental iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repeatability of Positron Emission Tomography (TEP) With fluorométhyl-(18F)-diméthyl-2-hydroxyéthyl-ammonium
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: fluorocholine PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Behavior Play Therapy and Culturally Adapted Mindfulness-Based Guided Self-Help for Parents
Status: COMPLETED
Conditions: Emotional Problem|Behavior Problem
Interventions: BEHAVIORAL: Group 1: Play Therapy|BEHAVIORAL: Group 2: Mindful Parenting|BEHAVIORAL: Group 3: (Combined Interventions of both Group 1 & 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoid Treatment in Addison's Disease
Status: COMPLETED
Conditions: Addison's Disease
Interventions: DRUG: Solu-Cortef (hydrocortisone)|DRUG: Cortef (hydrocortisone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopy Screening for High-risk Population of Lung Cancer With Severe Smoking With Negative LDCT Screen
Status: UNKNOWN
Conditions: Heavy Smoking
Interventions: PROCEDURE: white light bronchoscopy & autofluorescence bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect of Heart Sound and White Noise on Pain and Physiological Parameters During Hepatitis B Vaccine Injection
Status: RECRUITING
Conditions: Pain, Acute|Newborn; Vitality
Interventions: BEHAVIORAL: Heart Sound|BEHAVIORAL: White Noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ZD6474 Alone and in Combination With Retinoic Acid in Pediatric Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: ZD6474|DRUG: Retinoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Concussion Assessment of Rest and Exertion
Status: COMPLETED
Conditions: Concussions|Post-Concussive Symptoms
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Rest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pidotimod in Children With Recurrent Respiratory Tract Infections (RRI)
Status: COMPLETED
Conditions: Recurrent Respiratory Tract Infections
Interventions: DRUG: Pidotimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Arterial Imaging of Inflammation and Resolution After Endovascular Surgery
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Claudication, Intermittent|Claudication|PAD|SFA - Superficial Femoral Artery Stenosis|Iliac Artery Disease|Vascular Calcification
Interventions: DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Novel Disposable Flexible Ureteroscope for the Treatment of Renal Calculi
Status: COMPLETED
Conditions: UTI|Stone, Kidney
Interventions: DEVICE: Storz Flex-XC1 Disposable Flexible Ureteroscope|DEVICE: Storz Flexible Digital Ureteroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Dose-Ranging Study of 50 µg to 100 µg LSD in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide (LSD) 50µg|DRUG: Lysergic Acid Diethylamide (LSD) 75µg|DRUG: Lysergic Acid Diethylamide (LSD) 100µg|DRUG: Placebo/Lysergic Acid Diethylamide (LSD) 75µg|DRUG: Lysergic Acid Diethylamide (LSD) 50µg/75µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Primary PCI vs. Post-thrombolysis PCI as Reperfusion Strategies in STEMI
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: OTHER: Reperfusion strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Test the Response to Different Vaccination Regimens With an H5N1 Vaccine With AS03 in Adults Aged 18-64
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A (H5N1) Virus Monovalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Nitric Oxide Synthase Isoforms in the Cardiovascular Effects of Air Pollution
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: PROCEDURE: Forearm vascular study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy of ALKS 3831 on Body Weight in Young Adults Who Have Been Recently Diagnosed With Schizophrenia, Schizophreniform, or Bipolar I Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizophreniform Disorders|Bipolar I Disorder
Interventions: DRUG: ALKS 3831|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Combined Behavioral Interventions on Cognitive Outcomes in MCI
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Walking Intervention|BEHAVIORAL: Cognitive Training Intervention|BEHAVIORAL: Combined Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effectiveness Study on a Virtual Reality Based Training System for Stroke Patients
Status: COMPLETED
Conditions: Cerebrovascular Accident|Hemorrhagic Stroke|Stroke
Interventions: DEVICE: YouGrabber training device from YouRehab Ltd.|OTHER: Therapy (PT, OT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foley Catheter Versus PGE2 for Labor Induction at Term: a Pilot Study
Status: SUSPENDED
Conditions: Labor Induction|Induced Delivery
Interventions: DEVICE: Induction of labor with Foley catheter|DRUG: Induction of labor with PGE2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia
Status: WITHDRAWN
Conditions: Pain, Postoperative|Obesity|Respiratory Insufficiency
Interventions: DRUG: Intrathecal Morphine|DRUG: Intravenous hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and the Safety After Administration of "BR1017-1" and Co-administration of "BR1017-1A" and "BR1017-1B"
Status: COMPLETED
Conditions: Essential Hypertension|Primary Hypercholesterolemia
Interventions: DRUG: BR1017-1|DRUG: BR1017-1A|DRUG: BR1017-1B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Home-based Lifestyle Intervention for Optimizing Surgical Outcomes Among Urinary Bladder Cancer Patients
Status: RECRUITING
Conditions: Bladder Cancer|Cystectomy|Chemotherapy
Interventions: COMBINATION_PRODUCT: Dietary and Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Safety and Efficacy of Etrasimod in Subjects With Moderate-to-Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Etrasimod 1 mg|DRUG: Etrasimod 2 mg|DRUG: Etrasimod matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-199
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: ABT-199|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allopurinol Effect on MDA,NO,KIM-1 Urine Levels, RI and Renal Elastography in Kidney Stone Patients Post ESWL
Status: COMPLETED
Conditions: Kidney Calculi
Interventions: DRUG: Allopurinol Tablet 300 mg|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adding a Genetic Risk Evaluation to Standard Breast Cancer Risk Assessment for African American and Hispanic Women
Status: RECRUITING
Conditions: Breast Atypical Ductal Hyperplasia|Breast Atypical Lobular Hyperplasia|Breast Carcinoma|Breast Lobular Carcinoma In Situ
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Genotyping|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Extension Study to WA19977 in Patients With Active Polyarticular-Course Juvenile Idiopathic Arthritis
Status: TERMINATED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: RoActemra/Actemra (tocilizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative/Neoadjuvant Therapy and Vascular Debranching Followed by Resection for Locally Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreas Cancer
Interventions: PROCEDURE: Visceral Debranching
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BEHAVIORAL: UR-GOAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults
Status: COMPLETED
Conditions: Ewing's Sarcoma
Interventions: DRUG: Chemotherapy|PROCEDURE: Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Self-Moxibustion Therapy on Subjective Physical Symptoms and Health-related Quality of Life of the Elderly. The Effects of Self-Moxibustion Therapy
Status: COMPLETED
Conditions: Health Improvement of the Elderly
Interventions: OTHER: moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT