pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravitreal Aflibercept or Ranibizumab for Rubeosis Iridis
Status: COMPLETED
Conditions: Glaucoma|Rubeosis Iridis
Interventions: DRUG: Aflibercept|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PyloPlus Urea Breath Test System Pediatric Safety and Efficacy Study
Status: RECRUITING
Conditions: Helicobacter Pylori|Safety|Efficacy
Interventions: COMBINATION_PRODUCT: PyloPlus Urea Breath Test System|DIAGNOSTIC_TEST: Stool Antigen Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Modified Natural Cycle Offers a Chance of Pregnancy in Patients With Poor Response and High Basal FSH
Status: COMPLETED
Conditions: Infertility|Premature Ovarian Failure
Interventions: DRUG: recombinant FSH (Puregon, Organon, The Netherlands)|DRUG: GnRH antag: Ganirelix (Orgalutran, Organon, The Netherlands)|DRUG: hCG (Pregnyl, Organon, The Netherlands)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Comparative Study of Sleeve Gastrectomy Versus MGB and SASI Bypass , Randomized Study
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2 in Obese
Interventions: OTHER: metabolic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 827 in Subjects With Psoriatic Arthritis
Status: TERMINATED
Conditions: Psoriatic Arthritis
Interventions: DRUG: AMG 827 140|DRUG: Placebo|DRUG: AMG 827 280|DRUG: AMG 827 210
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal
Status: COMPLETED
Conditions: Delirium|AAA|Intensive Care Unit Delirium|Surgery--Complications|Surgery|Aortic Aneurysm, Abdominal
Interventions: OTHER: Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo Effects Investigated by Different Experimental Designs
Status: UNKNOWN
Conditions: Caffeine|Placebo|Baseline
Interventions: DIETARY_SUPPLEMENT: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Model of Hospital-Territory Management Coordinated by a Case Manager to Improve the Care of Patients With Parkinsonism.
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease|Atypical Parkinsonism|Secondary Parkinsonism|Nurse-Patient Relations|Nurse Physician Relations
Interventions: OTHER: Case Manager|OTHER: Standard-of-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of DM on Artery Blood Flow and Complications After Radial Artery Cannulation
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: duplex Doppler ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Satralizumab in Aneurysmal Subarachnoid Hemorrhage
Status: WITHDRAWN
Conditions: Aneurysmal Subarachnoid Hemorrhage|Delayed Cerebral Ischemia
Interventions: DRUG: Satralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of a Turmeric and Black Cumin Seed Formulation on Cholesterol Levels
Status: COMPLETED
Conditions: Cholesterol Health
Interventions: DIETARY_SUPPLEMENT: Turmeric and Black Cumin Seed|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety of Tetanus, Diphtheria, Acellular Pertussis With 5 Acellular Pertussis Components (Tdap5) Vaccination During Pregnancy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pertussis (Whooping Cough)
Interventions: OTHER: Not applicable / database analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2B Study to Evaluate ASN002 in Subjects With Moderate to Severe Atopic Dermatitis (RADIANT)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: ASN002|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest
Status: TERMINATED
Conditions: Cardiac Arrest|Shock|Lactic Acidosis|Thiamin Deficiency
Interventions: DRUG: Thiamine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Proximal Muscle Strength Effects by Incorporating Proximal Muscle Lengthening
Status: ACTIVE_NOT_RECRUITING
Conditions: Proximal Muscle Strength|Proximal Muscle Lengthening
Interventions: OTHER: myofascial release|DEVICE: blood flow restriction|OTHER: myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Spirulina Supplementation In Recovery From Damaging Exercise
Status: RECRUITING
Conditions: Damage Muscle
Interventions: DIETARY_SUPPLEMENT: Spirulina supplement|PROCEDURE: Eccentric exercise|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes for Individuals With Serious Mental Illness and Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Bipolar Disorder|Depression|Psychotic Disorders|Schizophrenia
Interventions: BEHAVIORAL: Targeted Training in Illness Management (TTIM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma, Ocular|Melanoma, Cutaneous|Metastatic Melanoma|Melanoma, Mucosal|Liver Metastases
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab|PROCEDURE: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug
Status: COMPLETED
Conditions: Partial Seizures
Interventions: DRUG: Adjunctive Zonisamide|DRUG: Replacement with Zonisamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Auditory Stimuli on Heart Rate Variability (HRV) Among Patients With Acquired Brain Injury (ABI)
Status: UNKNOWN
Conditions: Acquired Brain Injury
Interventions: OTHER: Auditory Stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone and Vorinostat in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: vorinostat|DRUG: ixabepilone|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome (ACS)
Interventions: DRUG: Acid Nicotinique|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sunrise® a New Medical Device to Diagnose Sleep Apnea Syndrome
Status: COMPLETED
Conditions: Sleep Apnea Syndrome, Obstructive
Interventions: DIAGNOSTIC_TEST: Sunrise® solution|DIAGNOSTIC_TEST: Polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Development and Testing of a Mobile Health Application for Management of Gestational Diabetes
Status: RECRUITING
Conditions: Diabetes, Gestational|Telemedicine
Interventions: BEHAVIORAL: Develop a mobile app that supports self- management and treatment for Nepalese GDM patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B-Cell Non Hodgkin Lymphoma|B-Cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: anti-CD19 CAR T-cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Lidocaine, Dexmedetomedine and Their Combination in Direct Laryngoscopy Surgery
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DRUG: Nebulized Lidocaine|DRUG: Nebulized dexmedetomidine|DRUG: Nebulized lidocaine and dexmedetomidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With SoC, Versus SoC Alone, in Adult Male Patients With mHSPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: DRUG: 177Lu-PSMA-617|DRUG: 68Ga-PSMA-11|DRUG: ARDT|DRUG: ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy in Participants With Metastatic BRAF-mutant Melanoma Treated With Encorafenib With and Without Binimetinib in Combination With Nivolumab and Low-dose Ipilimuma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: encorafenib|DRUG: nivolumab|DRUG: ipilimumab|DRUG: binimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE)
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Bronchiectasis|Interstitial Lung Disease|Lung Cancer|Asthma|Dyspnea|Fibrotic Lung Disease|Chronic Lung Disease
Interventions: OTHER: SELF-BREATHE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cricoid Pressure on Macintosh, McGrath X-Blade and Glidescope Videolaryngoscopes in Rapid Sequence Induction Intubation
Status: COMPLETED
Conditions: Rapid Sequence Induction Intubation
Interventions: DEVICE: Macintosh|DEVICE: Glidescope|DEVICE: McGrath MAC X-Blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ibuprofen Extended-Release Dental Pain Study
Status: COMPLETED
Conditions: Pain|Post-Operative Pain|Third Molar Extraction
Interventions: DRUG: Ibuprofen 600 mg Extended-Release Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Evaluation of PL2200 Versus Enteric-Coated and Immediate Release Aspirin in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PL2200 Aspirin Capsules|DRUG: Immediate-Release Aspirin Tablets|DRUG: Enteric-coated aspirin caplets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions
Status: COMPLETED
Conditions: Wrinkle|Fine Lines|Crepey Skin|Acne Scars|Acne|Enlarged Pores|Stretch Marks|Loose Skin
Interventions: DEVICE: Potenza
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing an Evidence-based Computerized Decision Support System Linked to Electronic Health Records to Improve Care for Cancer Patients
Status: COMPLETED
Conditions: Medical Oncology
Interventions: OTHER: computer reminders on clinical practice|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Austria Study - Analysis of Difference Between Active and Passive Fixation Leads
Status: COMPLETED
Conditions: Bradycardia|Heart Block|Sick Sinus Syndrome
Interventions: DEVICE: Flextend II, Fineline 2, Fineline Atrial J, Selute Picotip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis|IPF
Interventions: DRUG: tipelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of an Early Discharge Protocol After Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Morbid Obesity|Sleeve Gastrectomy|Early Discharge|Safety Issues
Interventions: OTHER: Early discharge|OTHER: Conventional protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RC48 Combined With Tislelizumab for Bladder Sparing Treatment in NMIBC With BCG Treatment Failure and HER2 Expression
Status: RECRUITING
Conditions: Non-Muscle Invasive Bladder Cancer|HER2
Interventions: DRUG: RC48|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Platelet, Endothelial and Vascular Function
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: EPA-rich triacylglycerol oil|DIETARY_SUPPLEMENT: Placebo - olive oil (BP specification)|DIETARY_SUPPLEMENT: DHA-rich triacylglycerol oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: COMPLETED
Conditions: Cancer|Prostate Cancer
Interventions: DRUG: ADXS31-142|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Exercise Following Pulmonary Embolism
Status: WITHDRAWN
Conditions: Pulmonary Embolism
Interventions: BEHAVIORAL: 8-weeks supervised exercise program|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Safety, Efficacy and Tolerability of AZD8233 Treatment in Participants With Hyperlipidaemia
Status: COMPLETED
Conditions: Hyperlipidaemia
Interventions: DRUG: AZD8233|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Blood Sampling Methods for Hemoglobin Measurement
Status: COMPLETED
Conditions: Anemia
Interventions: DEVICE: Blood source: single and pooled capillary and venous blood|DEVICE: Blood source: single capillary and venous blood|DEVICE: Blood source: pooled capillary and venous blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ERGT for Women Engaging in NSSI - an Effectiveness Study
Status: COMPLETED
Conditions: Borderline Personality Disorder|Non-suicidal Self-injury (NSSI)
Interventions: BEHAVIORAL: Emotion Regulation Group Therapy (ERGT).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Stellate Ganglion Block in Children With Autistic Disorder
Status: WITHDRAWN
Conditions: Autistic Disorder
Interventions: BEHAVIORAL: Routine therapy|PROCEDURE: Stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CS1001 in Subjects With Relapsed or Refractory Extranodal Natural Killer/ T Cell Lymphoma(ENKTL)
Status: COMPLETED
Conditions: Extranodal Natural Killer/T-Cell Lymphoma
Interventions: BIOLOGICAL: CS1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial With Metformin in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effect of Remimazolam and Propofol on Perioperative Hypothermia Under Spinal Anesthesia
Status: COMPLETED
Conditions: Lower Extremity Problem|Gynecologic Disease|Urinary Tract Disease
Interventions: DRUG: Propofol|DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Adding Isoflavonoids to Clomiphene Citrate for Ovulation Induction in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Ovulation Induction|Polycystic Ovary Syndrome
Interventions: DRUG: Rosafem (FEMININE FORMULA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Amputations by Tailored Risk-based Intervention to Optimize Therapy
Status: COMPLETED
Conditions: Diabetes|Foot Ulcer
Interventions: BEHAVIORAL: Personalized Behavioral Intervention|BEHAVIORAL: Current Best Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Adherence to Improve Effectiveness of Cardiovascular Disease Therapies
Status: COMPLETED
Conditions: Diabetes Mellitus|Cardiovascular Disease
Interventions: OTHER: Interactive Voice Recognition (IVR) phone calls|OTHER: Educational mailings and follow-up for nonadherence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Efficacy of 532nm Laser and 1064 nm Laser in the Treatment of Cutaneous Lupus Erythematous Versus Topical Corticosteroids Alone
Status: TERMINATED
Conditions: Cutaneous Lupus
Interventions: DEVICE: 532nm laser|DEVICE: 1064nm laser|DRUG: Topical corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Different Messaging Approaches to Increase Activation of a HealthyFood Benefit in Adults With Diabetes
Status: COMPLETED
Conditions: Diabetes|Diet|Incentives|Messaging
Interventions: OTHER: Email message regarding the HealthyFood benefit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Safety of Use of Anti-IL6 Receptor Antibodies to Reduce Allo-sensitization Post Allograft Nephrectomy
Status: RECRUITING
Conditions: Kidney Transplantation|Graft Failure
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HPV Specific Immunotherapy in Participants With HPV Associated Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Cancer
Interventions: BIOLOGICAL: INO-3112|DEVICE: CELLECTRA™-5P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Effect of Virtual Reality and Kinetic Chain Exercises in Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Non immersive virtual reality ( xbox kinetic)|OTHER: Kinetic chain exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Strength Program Over Cognitive Functionality in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Cognitive Impairment|Aging Problems
Interventions: PROCEDURE: Strength training in older adults with mild or non existent cognitive impairment|PROCEDURE: Multimodal excercise in older adults with mild or non existent cognitive impairment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Follow Up Protocol for NiCord®/CordIn™ (Omidubicel) Patients
Status: COMPLETED
Conditions: Patients Transplanted With NiCord/CordIn (Omidubicel)
Interventions: GENETIC: NiCord®/CordIn™ (omidubicel)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Study of 2 Doses of ATV/r OD + 2 NRTIs in Thai HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy to Reduce Comorbidity in Spinal Surgery
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: RADIATION: Low Level Laser Therapy|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extention Study of Safety of Canakinumab in Japanese Patients With Periodic Fever Syndromes
Status: COMPLETED
Conditions: Periodic Fevers Syndrome
Interventions: BIOLOGICAL: Canakinumab (AIN457)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proteinase 3 PR1 Peptide Mixed With Montanide ISA-51 VG Adjuvant and Administered With GM-CSF and PEG-INTRON(R)
Status: TERMINATED
Conditions: Leukemia
Interventions: BIOLOGICAL: Peptide Vaccine (PR1 Peptide)|DRUG: Peginterferon alfa-2b|DRUG: Imatinib|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting Functionality in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer Female|Breast Cancer Lymphedema|Breast Carcinoma in Situ|Hand Grasp|Pain, Shoulder
Interventions: OTHER: Tissue Dielectric Constant Measurement|OTHER: Muscle strength measurement|OTHER: Hand-Grip Strength Measurement|OTHER: Pain Threshold Measurement|OTHER: International Physical Activity Questionnaire-Short Form (IPAQ-SF)|OTHER: Fatigue Impact Scale|OTHER: Disabilities of Arm, Shoulder and Hand Scale (DASH)|OTHER: Exercise Benefits/ Barriers Scale|OTHER: Beck Depression Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Subacute Effect of Tolvaptan on Total Kidney Volume in Adult Patients With Autosomal Dominant Polycystic Kidney Disease
Status: UNKNOWN
Conditions: Autosomal Dominant Polycystic Kidney
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Chronic Exposure to Radiofrequency Electromagnetic Fields on Neurophysiological Development in the Preterm Neonate
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant|Exposure to Radiofrequency
Interventions: OTHER: Parental questionnaire|OTHER: Daily continuous recording of radiofrequency exposure levels|OTHER: Follow-up of daily infants environmental and clinical parameters|OTHER: Nocturnal polysomnography|DIAGNOSTIC_TEST: cerebral hemodynamics|DIAGNOSTIC_TEST: activity of the autonomic nervous system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Study on the Efficacy and Safety of Hetropapa Ethanolamine Tablets in the Treatment of Thrombocytopenia Caused by Concurrent Radiotherapy and Chemotherapy in Cervical Cancer
Status: UNKNOWN
Conditions: Tumor Chemotherapy-related Thrombocytopenia
Interventions: DRUG: Herombopag Olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mindfulness-based Applied to Hemodialysis Patients on Psychosocial Adaptation
Status: COMPLETED
Conditions: Hemodialysis|Psychosocial Adaptation
Interventions: BEHAVIORAL: Mindfulness-based Applied|BEHAVIORAL: Active Comparator: Control groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Palbociclib and Cetuximab in Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of the Colon|Colon Cancer|Colon Neoplasms|Colonic Cancer|Neoplasms, Colonic
Interventions: DRUG: Cetuximab|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADVP005; Dengue CVD 12000 - Dengue-1-Virus Live Virus Human Challenge (DENV-1-LVHC)
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: Dengue 1 Live Virus Human Challenge (DENV-1-LVHC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma, Gastric Carcinoma, Gastroesophageal Junction Carcinoma
Interventions: DRUG: Tislelizumab|DRUG: Cisplatin|DRUG: 5-FU|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacral Nerve Stimulation Therapy for the Treatment of Chronic Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: InterStim Sacral Nerve Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multicentre, Open-label Randomised Controlled Study to Investigate the Effectiveness of Pamidronate in the Prevention of Bone Loss in de Novo Renal Transplant Patients.
Status: COMPLETED
Conditions: Bone Loss
Interventions: DRUG: Pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VBMI to Increase Treatment Completion With MK-MK-5172/MK-8742 Among Veterans With Active Substance Use Disorders Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Patient Adherence, Chronic Hepatitis C, Alcohol-related Disorders
Interventions: BEHAVIORAL: VBMI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immune Response of mRNA-1345, a Vaccine Targeting Respiratory Syncytial Virus (RSV), When Co-administered With a Fluzone HD, in Adults ≥65 Years of Age
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: mRNA-1345|BIOLOGICAL: Fluzone HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects Of Volume Control Guided by Body Composition Monitor (BCM) on Blood Pressure and Cardiac Condition in Hemodialysis Patients
Status: COMPLETED
Conditions: Left Ventricular Hypertrophy
Interventions: DEVICE: BCM|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of "KB-120" Small Molecular Nutrient in Women With Decreased Ovarian Reserve
Status: NOT_YET_RECRUITING
Conditions: Diminished Ovarian Reserve
Interventions: DIETARY_SUPPLEMENT: "KB-120" small molecular nutrient and vitamin E|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymmetric Primary Closure and Additional Skin Excision Technique.
Status: COMPLETED
Conditions: Pilonidal Sinus|Pilonidal Disease of Natal Cleft|Surgical Technique
Interventions: PROCEDURE: Asymmetric Primary Closure and Additional Skin Excision Technique|PROCEDURE: Standard Karydakis technique.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective & Prospective Observational Study of Patients With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura|Thrombocytopenia|Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)|Thrombocytopenic Purpura
Interventions: OTHER: Retrospective Chart Review|OTHER: Patient-reported Outcome Questionnaires|OTHER: Physician Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimizing Self-management COPD Treatment Through the American Lung Association Helpline
Status: COMPLETED
Conditions: Copd
Interventions: BEHAVIORAL: Self-management education (short)|BEHAVIORAL: Ground-based walking training|BEHAVIORAL: Inhaler training|BEHAVIORAL: Caregiver support|BEHAVIORAL: Self-management education (long)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Milvexian|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DNA Repair Capacity of Afamelanotide on Ultraviolet Radiation-induced DNA Damage in Healthy Volunteers
Status: COMPLETED
Conditions: Afamelanotide Evaluated as Skin DNA Repair Therapy in Healthy Volunteers
Interventions: DRUG: Afamelanotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Patient Reported Knowledge and Satisfaction Following the Use of an Enhanced Gynecologic Brachytherapy-Specific Educational Video
Status: COMPLETED
Conditions: Cervical Cancer|Uterine Cancer
Interventions: OTHER: Brachytherapy video|OTHER: Standard Brachytherapy Consent Process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults
Status: COMPLETED
Conditions: Dental Caries|Hydroxyapatite|Tooth Decay|Dentin, Carious|Enamel Caries
Interventions: OTHER: Experimental.|OTHER: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Single Doses of ORM-12741
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ORM-12741 MR A|DRUG: ORM-12741 IR|DRUG: ORM-12741 MR B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Mapatumumab in Combination With Bortezomib (Velcade) and Bortezomib Alone in Subjects With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Mapatumumab|BIOLOGICAL: Mapatumumab|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palbociclib in Combination With Adjuvant Endocrine Therapy for Hormone Receptor Positive, HER2 Negative Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clear Corneal Incisions and Arcuate Incisions Utilizing FemtoSecond Laser Technology for Cataract Surgery
Status: COMPLETED
Conditions: Cataracts
Interventions: PROCEDURE: Femtosecond Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Single Agent Idelalisib Followed by Idelalisib in Combination With Chemotherapy in Adults With Metastatic Pancreatic Ductal Adenocarcinoma
Status: TERMINATED
Conditions: Previously Untreated Pancreatic Ductal Adenocarcinoma|Relapsed/Refractory Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Idelalisib|DRUG: Nab-paclitaxel|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveillance and Treatment With Dihydroartemisinin-piperaquine Plus Primaquine
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: dihydroartemisinin-piperaquine|DRUG: primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Aerobic Exercise and Computerized Cognitive Stimulation in Patients With Schizophrenia - A Randomized Controlled Trial
Status: RECRUITING
Conditions: Schizophrenia|Exercise|Computerized Cognitive Stimulation
Interventions: OTHER: cognitive stimulation|OTHER: physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Bevacizumab and Erlotinib in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Adenocarcinoma of the Pancreas
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychotic, in Adults With Schizophrenia, as Measured Positron Emission Tomography (PET) Imaging
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SEP-363856
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Cetirizine HCl Tablets 10 mg and Zyrtec® 10 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetirizine HCl Tablets 10 mg|DRUG: Zyrtec® 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore
Status: UNKNOWN
Conditions: Critical Lower Limb Ischemia|Peripheral Artery Disease
Interventions: DEVICE: SELUTION Sirolimus DCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buccal Estrogen in Toothpaste Study: Systemic Absorption of Estradiol When Administered Mixed With Toothpaste in Postmenopausal or Surgically Menopausal Women
Status: COMPLETED
Conditions: Menopause|Postmenopause
Interventions: DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The LAVA (Lateral Flow Antigen Validation and Applicability) Study for COVID-19
Status: COMPLETED
Conditions: This is a Pilot Study Which Aims to Assess the Validity and Applicability of Lateral Flow Assays (LFAs) Which Can be Used as a Point of Care Test for COVID-19|Covid19
Interventions: DEVICE: Innova Lateral Flow Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Burden Comorbidities and Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Symptomatic Severe Aortic Valve Stenosis in Older Patients
Interventions: OTHER: answering to questionnaires of quality of live
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Efficacy Study Comparing SYMBICORT® Pressurised Metered Dose Inhaler (pMDI) With Budesonide Hydrofluoroalkanes (HFA) pMDI, in Hispanic Subjects With ICS Dependent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol (SYMBICORT) pMDI|DRUG: Budesonide HFA pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-PCI:Cardiac Imaging in Patients With Diabetes to Detect Coronary Artery Blockages Previously Opened by Angioplasty
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Coronary Restenosis
Interventions: DRUG: Technetium Tc99m Sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pretreatment With Mifepristone Prior to Mirena Insertion
Status: COMPLETED
Conditions: Women in Need of Long Acting Reversibel Cntraception With the Intrauterine Levonorgestrel Releasing System, Mirena
Interventions: DRUG: Mifepristone prior to Mirena|DRUG: Placebo prior to Mirena insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ranibizumab Intravitreal Injections Versus Dexamethasone Intravitreal Implant in Patients With Branch Retinal Vein Occlusion (BRVO)
Status: COMPLETED
Conditions: Visual Impairment|Macular Edema|Branch Retinal Vein Occlusion
Interventions: DRUG: Ranibizumab|OTHER: Dexamethasone Implant|OTHER: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rotation Stability of Toric Intraocularlens (IOL) Compared Sitting Against Lying After Cataract Operation
Status: RECRUITING
Conditions: Astigmatism
Interventions: OTHER: catarct surgery with toric intra ocular lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic Seizures
Status: TERMINATED
Conditions: Nonconvulsive Electrographic Seizures
Interventions: DRUG: Brivaracetam intravenous solution|DRUG: Brivaracetam oral tablets|DRUG: Phenytoin intravenous solution|DRUG: Phenytoin oral tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of Lung Recruitment During General Anesthesia and Low-tidal Volume Ventilation
Status: COMPLETED
Conditions: Anesthesia, General|Surgery
Interventions: DRUG: Fluid resuscitation or amine administration|DRUG: General anesthetic|DRUG: Fluid administration|PROCEDURE: Low-tidal volume ventilation|PROCEDURE: Scheduled recruiting maneuvers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002)
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Mental Disorders|Dyssomnias|Sleep Disorders|Sleep Disorder, Intrinsic
Interventions: DRUG: Esmirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The REDEEM Pilot Study: A Feasibility RCT of Early ECMO in Severe Acute Respiratory Infection, Including COVID-19, WHO
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Severe Acute Respiratory Infection|Covid19
Interventions: OTHER: VV-ECMO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative Care Outcomes in the Management of Malignant Ascites by Interventional Radiology
Status: WITHDRAWN
Conditions: Refractory Malignant Ascites
Interventions: PROCEDURE: Paracentesis|DEVICE: Tunneled Intraperitoneal Drain (IPD)|DEVICE: Peritoneal-Venous shunts (PVS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Naltrexone Therapy for Complex Regional Pain Syndrome
Status: RECRUITING
Conditions: Complex Regional Pain Syndrome|Chronic Pain|Causalgia|Complex Regional Pain Syndrome Type I|Complex Regional Pain Syndrome Type II
Interventions: DRUG: Low dose naltrexone|DRUG: Placebo sugar capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Music Playlist Based on ISO-Principle for De-escalating Agitation of People Living With Dementia
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Music listening|BEHAVIORAL: Audio Book Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia
Status: TERMINATED
Conditions: Labor Pain
Interventions: DRUG: Morphine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Surufatinib Combined With JS001 in the Treatment of Advanced Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Surufatinib/humanized anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Saxagliptin on Endothelial Function
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy With or Without Short-term Adjuvant Androgen-Deprivation Therapy in Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Adjuvant Androgen-Deprivation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response
Status: COMPLETED
Conditions: Diabetes Prevention|Obesity Prevention
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Comparison of Clinical Outcomes Between Everolimus-eluting Bioresorbable Vascular Scaffold Versus Everolimus-eluting Metallic Stent in Long Coronary Lesions
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: PCI with Absorb everolimus-eluting bioresorbable vascular scaffold|DEVICE: PCI with Xience everolimus-eluting metallic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CONTROL Walking Study
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: practice of a complex walking task|DEVICE: Dosage A: transcranial direct current stimulation (tDCS)|DEVICE: Dosage B: transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE