pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic
Status: COMPLETED
Conditions: Ventilation During Resuscitation
Interventions: PROCEDURE: Mout-to-mouth ventilation|PROCEDURE: Mout-to-mouth ventilation with quantitative analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacy Interventions to Improve Chronic Disease Medication Refill
Status: COMPLETED
Conditions: Diabetes|Hypertension|Hyperlipidemia|Heart Diseases|Depression|Psychoses
Interventions: BEHAVIORAL: pharmacist contact with the patient via telephone|BEHAVIORAL: Pharmacist contact with the patient's physician via fax|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adoptive Cellular Immunotherapy Following Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma|Transplant-eligible Patients
Interventions: BIOLOGICAL: Ex-vivo expanded effector cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endotracheal Intubation Over the Aintree Via the I-gel and Laryngeal Mask Airway Supreme
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: LMA-Supreme supraglottic device|DEVICE: I-gel supraglottic device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measles and BCG Vaccines for Mother and Child
Status: RECRUITING
Conditions: Vaccine Preventable Disease|Measles|Mother-Infant Interaction|BCG Vaccination Reaction
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: Measles vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Microneurography Study of NaV1.8 Inhibition in Healthy Adults
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-150|DRUG: VX-548|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interpretation of Health News Items Reporting Results of Pre-clinical Studies With or Without Spin By French-speaking Patients
Status: WITHDRAWN
Conditions: The Study Focus on no Specific Condition
Interventions: OTHER: News items with spin|OTHER: News items without spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effectiveness of Thoracic Mobilization Exercise in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: conventional physiotherapy|OTHER: thoracic mobilization methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.
Status: COMPLETED
Conditions: Breast Cancer|Lung Cancer|Hepatocellular Cancer|Colorectal Cancer|Pancreatic Cancer|Renal Cancer
Interventions: DRUG: NIS793|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo
Status: COMPLETED
Conditions: Mild Gestational Diabetes
Interventions: DRUG: Glyburide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bariatric Surgeries on Glucose Metabolism
Status: RECRUITING
Conditions: Post Bariatric Surgery|Gastric Bypass|Sleeve Gastrectomy|Hypoglycemia After Gastric Bypass
Interventions: DRUG: Exendin-(9-39)|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Intraocular Melanoma|Lung Cancer|Melanoma (Skin)|Metastatic Cancer|Neuroblastoma|Ovarian Cancer|Retinoblastoma|Sarcoma|Small Intestine Cancer
Interventions: GENETIC: DNA analysis|OTHER: immunologic technique|OTHER: pharmacological study|RADIATION: iodine I 131 monoclonal antibody 3F8|RADIATION: 131I-3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of This Study is to Evaluate the Pharmacokinetic Properties of Intravitreal Ocriplasmin Prior to Planned Primary Pars Plana Vitrectomy (PPV)
Status: COMPLETED
Conditions: Vitrectomy
Interventions: DRUG: ocriplasmin|DRUG: ocriplasmin|DRUG: ocriplasmin|DRUG: ocriplasmin|DRUG: ocriplasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Bronchitis
Interventions: DEVICE: RheOx Bronchial Rheoplasty|DEVICE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Plexus and Suprainguinal Fascia Iliaca Blocks For Total Hip Replacement
Status: COMPLETED
Conditions: Hip Osteoarthritis|Pain, Acute|Pain, Postoperative|Opioid Use
Interventions: PROCEDURE: lumbar plexus block|PROCEDURE: suprainguinal fascia iliaca block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Cognitive Difficulties After Cancer Treatments in Women Treated for Breast Cancer: Feasibility Study (Step 1 of the Cog-Stim Protocol)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Cognitive stimulation sessions coupled with Adapted Physical Activity sessions.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Eye Health|Age-related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Freeze-dried table grape powder|DIETARY_SUPPLEMENT: Placebo of the table grape powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Normalizing CO2 in Chronic Hyperventilation by a Novel Breathing Mask: A Pilot Study
Status: COMPLETED
Conditions: Hyperventilation|Chronic Idiopathic Hyperventilation|Dysfunctional Breathing|Respiratory Alkalosis
Interventions: DEVICE: Partial Rebreathing Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denosumab Versus Zoledronic Acid in Thalassemia-Induced Osteoporosis
Status: TERMINATED
Conditions: Thalassemia Majors (Beta-Thalassemia Major)|Osteoporosis
Interventions: DRUG: Denosumab 60 MG/ML Prefilled Syringe|DRUG: Zoledronic Acid 5Mg/Bag 100Ml Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research of Licartin Combined With TACE in the Treatment of Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Licartin|PROCEDURE: Transcatheter arterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of ARC-520 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ARC-520|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
Status: RECRUITING
Conditions: Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
Interventions: GENETIC: AAV2-hAQP1 Concentration 1|GENETIC: AAV2-hAQP1 Concentration 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab Expanded T-cells (BET) in Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Blinatumomab Expanded T-cells (BET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Enfortumab Vedotin in People With Urothelial Carcinoma of the Upper Urinary Tract
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Enfortumab Vedotin|PROCEDURE: Radical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phytomedicines Versus Hydroxychloroquine as an Add on Therapy to Azythromycin in Asymptomatic Covid-19 Patients
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Hydroxychloroquine/Azithromycine|COMBINATION_PRODUCT: Quinquina-Stevia/Azythromycin|COMBINATION_PRODUCT: 4Plants/Azythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: DRUG: Sodium Chloride 0.9% infusion alone or in combination with Sodim acetate with normal saline in a ratio 1;1, 2;1 and 3;1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK/PD of FE 203799 in Adults With Lymphomas
Status: WITHDRAWN
Conditions: Lymphoma, Non-Hodgkin's, Adult|Lymphoma, Hodgkin's, Adult
Interventions: DRUG: FE 203799
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cementation Techniques for Single-tooth Implant Crowns
Status: COMPLETED
Conditions: Cementation (MeSH Unique ID: D002484)|Dental Implant-Abutment Design (MeSH Unique ID: D059605)|Crown (MeSH Unique ID: D003442) Surfaces|Contour: Crown (MeSH Unique ID: D003442) - Dental Implant (MeSH Unique ID: D015921) Abutment
Interventions: OTHER: zinc polycarboxylate (with the requirements of ISO 9917)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of PRG-1801 in Recurrent/Refractory Immune Thrombocytopenia (ITP)
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: PRG-1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Safety Evaluation of Two Over the Counter Analgesics
Status: COMPLETED
Conditions: Gastrointestinal Mucosal Damage
Interventions: DRUG: Ibuprofen|DRUG: Paracetamol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Orally Administrated JBM-TC4 Prevents Acute Radiodermatitis in Breast Cancer Patients
Status: UNKNOWN
Conditions: Radiodermatitis
Interventions: DRUG: 2000 mg of JBM-TC4 per day|DRUG: 3000 mg of JBM-TC4 per day|DRUG: 3000 mg of PEG-400 per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Autologous Mesenchymal Stem Cells in Patients With Multiple System Atrophy
Status: COMPLETED
Conditions: Multiple System Atrophy
Interventions: BIOLOGICAL: autologous mesenchymal stem cells|BIOLOGICAL: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Trunk Training in Patients With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: PROCEDURE: neurodevelopmental treatment|PROCEDURE: video-based trunk training|PROCEDURE: Video-based trunk training will apply with Theratogs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concomitant, Sequential, and Standard Triple Therapy for H. Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 7-day quadruple therapy|DRUG: 10-day sequential therapy|DRUG: 7-day standard triple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Versus Multiple-dose Antimicrobial Prophylaxis for Peroral Endoscopic Myotomy in Achalasia
Status: UNKNOWN
Conditions: Achalasia Cardia
Interventions: DRUG: One dose of Cefo-perazone Sulbactum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06305591|DRUG: PF-06305591|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Seville Cohort of People at Substantial Risk for HIV Infection on Pre-exposure Prophylaxis
Status: ENROLLING_BY_INVITATION
Conditions: HIV Infection Primary|Hepatitis, Viral, Human|Sexually Transmitted Infections, Excluding HIV and Hepatitis
Interventions: DRUG: Tenofovir Disoproxil Fumarate 300 MG Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Condylar Segment Repositioning Using CAD/CAM Generated Wafer After BSSO in Skeletal Mandibular Deformity
Status: UNKNOWN
Conditions: Skeletal Abnormalities
Interventions: OTHER: Bilateral Sagittal Split Osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: DRUG: Sirolimus|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Internal Hospital Practice: The Effect of Altered Test Tubes Sampling Order on Blood Culture Contamination Rates
Status: COMPLETED
Conditions: Septicemia
Interventions: DIAGNOSTIC_TEST: aspirating first blood volume into a regular blood collection tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Androgens in Man-4: (Short Title: Oral T-4)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Testosterone Enanthate|DRUG: Testosterone Enanthate|DRUG: Dutasteride|OTHER: placebo sesame oil|DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Newly Approved Drugs for Multidrug-resistant TB
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant|Infection, Bacterial|Pulmonary Tuberculoses
Interventions: DRUG: Bedaquiline|DRUG: Delamanid|DRUG: Clofazimine|DRUG: Levofloxacin|DRUG: Moxifloxacin|DRUG: Linezolid|DRUG: Pyrazinamide|DRUG: Control arm MDR-TB regimen, consistent with WHO guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Different Community Models of ART Delivery Amongst Stable HIV+ Patients in Two Urban Settings in Zambia
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: Community Adherence Clubs|OTHER: Home-Based ART Delivery|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone vs. Paroxetine for Panic Attacks
Status: TERMINATED
Conditions: Major Depressive Disorder With Panic Attacks|Panic Disorder
Interventions: DRUG: Risperidone|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Stress Echocardiography Versus Exercise ECG (ExECG) in Women With Chest Pain
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Exercise ECG|PROCEDURE: Stress Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega 3 and Vitamin D Dosage in a Population With Moderate to High Risk of AMD
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Vitamin D Deficiency
Interventions: DIAGNOSTIC_TEST: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Buccal Cancer Resection Ultrasound Guided
Status: NOT_YET_RECRUITING
Conditions: Buccal Mucosa Cancer|Squamous Cell Carcinoma
Interventions: DEVICE: Ultrasound-guided resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Intermittent Pneumatic Compression for Sports
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: DEVICE: Intermittent pneumatic compression (AirRelax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High Altitude
Status: COMPLETED
Conditions: High Altitude
Interventions: DRUG: Pioglitazone 15mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Ultrasound-guided Transverse-abdominal Plain Blockade in Urological Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Postoperative transverse abdominal plain (TAP) blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthetic Solution in the Bladder Prior to Botox Injections in the Bladder
Status: UNKNOWN
Conditions: Urge Incontinence|Overactive Bladder|Anesthesia, Local|Pain, Procedural|Urinary Tract Infections|Hematuria
Interventions: COMBINATION_PRODUCT: Alkalinized Lidocaine|DRUG: Placebo Sodium Chloride 0.9% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Systemic Bioactivity of Inhaled Nebulized RNS60
Status: COMPLETED
Conditions: Systemic Bioactivity of Nebulized RNS60
Interventions: DRUG: RNS60|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Rectal Cancer Study (MERCURY II)
Status: UNKNOWN
Conditions: Adenocarcinoma|Adenocarcinoma, Mucinous|Carcinoma|Neoplasms, Glandular and Epithelial|Neoplasms by Histologic Type|Neoplasms|Neoplasms, Cystic, Mucinous, and Serous|Colorectal Neoplasms|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms|Neoplasms by Site|Digestive System Diseases|Gastrointestinal Diseases|Intestinal Diseases|Rectal Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Instant Message-delivered Brief Internet-based Cognitive Behavioural Therapy (iCBT) for Post-stroke Depression
Status: RECRUITING
Conditions: Stroke|Depressive Symptoms|Mobile Phone Use
Interventions: OTHER: iCBT-based EMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: FLT3 Ligand Immunotherapy and Stereotactic Radiotherapy for Advanced Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: FLT3 Ligand Therapy (CDX-301)|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anxiety and COPD Evaluation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Anxiety Inventory for Respiratory Disease (AIR)|BEHAVIORAL: Hospital Anxiety and Depression Scale (HADS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D for Established Type 2 Diabetes (DDM2)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Cholecalciferol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Adapted at Home Supervised by Videoconferencing in Post-cancer for Children / AYA Treated for Leukemia (ONCOPED SAPATIC)
Status: TERMINATED
Conditions: Leukemia
Interventions: OTHER: Physical Activity Adapted program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Development of Behavior and Its Underlying Neural Correlates in Human Infants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: MRI/DTI|OTHER: EEG|OTHER: Eye Tracking|OTHER: Ages and Stages Questionnaire (ASQ)|OTHER: Infant Behavior Questionnaire Revised (IBQ-R)|OTHER: Beck Depression Inventory (BDI)|OTHER: The Brief Fear of Negative Evaluation Scale (BFNE)|OTHER: Edinburgh Postnatal Depression Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigating the Morbidity of Glucocorticoid Use in Patients With Autoimmune Bullous Diseases (AIBDs)
Status: ACTIVE_NOT_RECRUITING
Conditions: Autoimmune Bullous Dermatosis|Glucocorticoids Toxicity
Interventions: DRUG: GlucoCorticoid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inpatient Endoscopy Procedure Planning Delays and Impact on Length of Stay and 30-day Readmission
Status: NOT_YET_RECRUITING
Conditions: Inpatient Endoscopy Delay|Readmission|Prolonged Hospital Stay
Interventions: PROCEDURE: Inpatient gastrointestinal endoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ToFAcitinib in Early Active Axial SpondyloarThritis:
Status: NOT_YET_RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Tofacitinib 5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Xenical, Pionorm, Diroton, Diltiazem, Atorvastatin|DIETARY_SUPPLEMENT: "Analimentary detoxication"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camostat With Bicalutamide for COVID-19
Status: TERMINATED
Conditions: Covid19|SARS-CoV Infection|Coronavirus Infection
Interventions: DRUG: Camostat Mesilate|DRUG: Bicalutamide 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin And Longevity
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Metformin|RADIATION: PET-MRI Scan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Single-arm Study of Total Body Irradiation With Linac Based VMAT and IGRT
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematologic Malignancy
Interventions: RADIATION: Linac Based VMAT TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Smoking on miRNA-223 Before-After Non-Surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Therapy|miRNA-223|Periodontitis|Biomarker
Interventions: OTHER: experimental-periodontitis-mirna-223-gingival tissue-saliva samples|OTHER: control-clinical healthy mirna-223-gingival tissue-saliva samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Biomechanical Assessment of the AST Stabilimax BAR Using Radiostereometric Analysis (RSA)
Status: WITHDRAWN
Conditions: Assess Motion in Flexion/Extension and Lateral Bending of the Lumbar Vertebrae in Vivo Following Motion Sparing Surgery Using Radiostereometric Analysis (RSA.)
Interventions: DEVICE: RSA Beads
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of INO-1001, an Intravenous PARP (Poly [ADP Ribose] Polymerase) Inhibitor in Acute Heart Attack Patients Undergoing Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: INO-1001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Biomarker-Guided Optimization of Transcutaneous Vagal Stimulation for Atrial (BiG tVNS-AF)
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Stress Management With Application of Portable Devices in Occupational Populations
Status: UNKNOWN
Conditions: Stress, Psychological|Autonomic Nervous System Diseases|Emotional Stress
Interventions: BEHAVIORAL: The basic intervention|BEHAVIORAL: The personalized interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of The Accuracy of CAD-CAM Custom Made Titanium Miniplates In Positioning of the Genial Segment in Computer Guided Genioplasty
Status: UNKNOWN
Conditions: Macrogenia|Microgenia|Miniplate
Interventions: PROCEDURE: Osseous Genioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma
Status: COMPLETED
Conditions: Raynaud Disease
Interventions: DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Imaging Aid for Management of Cervical Lesions
Status: UNKNOWN
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasias|Digital Colposcopy|Precancerous Cervical Lesions
Interventions: DEVICE: Diagnostic imaging aid for one-visit management of cervical lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-Inflammatory and Anti-Coagulant Effects of Salmon Polar Lipids
Status: COMPLETED
Conditions: Platelet Thrombus
Interventions: DIETARY_SUPPLEMENT: Food Grade Extract of Salmon Polar Lipids (FGE-Salmon-PLs)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DEVICE: MagVenture MagProx100 Stimulator with a Cool-B65 A/P coil|DEVICE: eSHAM system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Previfenon® as Chemoprophylaxis of COVID-19 in Health Workers
Status: UNKNOWN
Conditions: COVID-19|SARS-CoV2
Interventions: DRUG: Previfenon®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: acTBS Treatment for Inpatient Subjects With Suicidality
Status: ACTIVE_NOT_RECRUITING
Conditions: Suicidality
Interventions: DEVICE: accelerated Thetaburst stimulation|DEVICE: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bipolar II Depression: Lithium, SSRI, or the Combination
Status: COMPLETED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: Sertraline|DRUG: Lithium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Corneal Staining Associated With Daily Disposable Beauty Contact Lenses
Status: TERMINATED
Conditions: Refractive Error
Interventions: DEVICE: etafilcon A|DEVICE: 2-HEMA, EGDMA Non-ionic|DEVICE: hefilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers
Status: COMPLETED
Conditions: Migraine|Sinusitis
Interventions: DRUG: almotriptan or pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thromboelastographic Profile in Healthy Newborns and Infants of Diabetic Mothers Using TEG6s
Status: UNKNOWN
Conditions: Thromboelastography|Coagulation; Fetus or Newborn|Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1|Diabetes, Gestational
Interventions: OTHER: Laboratory clotting studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of anle138b in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: anle138b|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ranolazine on Valvular Disease in Patients With Pacemakers
Status: UNKNOWN
Conditions: Ischemic Mitral Regurgitation
Interventions: DRUG: Ranolazine (Active drug)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HF-SRT vs. HS-WBRT in Treating Patients With Brain Oligometastases
Status: NOT_YET_RECRUITING
Conditions: Brain Oligometastases
Interventions: RADIATION: Hypofractionated Stereotactic Radiotherapy (HF-SRT)|RADIATION: Hippocampus-Sparing Whole-Brain Radiotherapy (HS-WBRT) plus memantine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Continuous Infusions vs Scheduled Bolus Infusions
Status: COMPLETED
Conditions: Surgical Procedure, Unspecified|Pain, Postoperative
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Chemotherapy and Avastin as Treatment for Women With Breast Cancer at High Risk for Relapse
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Gemcitabine and Capecitabine and Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses
Status: COMPLETED
Conditions: Abscesses
Interventions: DRUG: bactrim|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)
Status: COMPLETED
Conditions: Primary Hypercholesterolemia
Interventions: DRUG: ezetimibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Evaluating Mycophenolate Mofetil in Children With Nephrotic Syndrome After Rituximab Treatment
Status: WITHDRAWN
Conditions: Frequently Relapsing Nephrotic Syndrome|Steroid-Dependent Nephrotic Syndrome
Interventions: DRUG: Rituximab|DRUG: Mycophenolate Mofetil|DRUG: Placebo tablets matching Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Red Beetroot Juice Intake in Adults With Long COVID-19
Status: COMPLETED
Conditions: Long COVID
Interventions: DIETARY_SUPPLEMENT: Red Beetroot Juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Vandetanib|DRUG: Cyclophosphamide|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptomatic Efficacy of Microparticle Arterial Embolization in Knee Osteoarthritis Resistant to Medical Treatment
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Arteriography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of 0.5% Bupivacaine, 0.5% Levobupivacaine, and 0.5% Hyperbaric Bupivacaine
Status: COMPLETED
Conditions: Anesthesia, Spinal
Interventions: PROCEDURE: spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Abiraterone Acetate Plus LHRH Agonist and Abiraterone Acetate Plus LHRH Agonist and Enzalutamide
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Enzalutamide|DRUG: LHRHa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Low FODMAP Diet and Dietary Oligofructose on Gastrointestinal Form, Function and Microbiota
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: low FODMAP diet|DIETARY_SUPPLEMENT: Oligofructose|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study Relating to Patients Undergoing Medial Femoral Patellar Ligament Reconstruction
Status: RECRUITING
Conditions: Patellofemoral Dislocation
Interventions: PROCEDURE: MPFL reconstruction with fascia lata allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Treatment Efficacy in Oral Lichen Planus: The Role of Salivary Biomarkers
Status: COMPLETED
Conditions: Oral Lichen Planus|Oral Lichen Planus Related Stress
Interventions: COMBINATION_PRODUCT: Acetonide triamcinolone 0.2% +hyaluronicacid 1%|DRUG: Corticoid Acetonide triamcinolone 0.2%|DRUG: Hyaluronic acid 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effects of AZD6140 in Patients With Renal Impairment and in Healthy Volunteers
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: AZD6140
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions
Status: COMPLETED
Conditions: Premalignant Vulvar Lesion|Benign Vulvar Lesion
Interventions: DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot-Tart Cherry, Mitral Transcriptome, and POAF Incidence
Status: RECRUITING
Conditions: Post-operative Atrial Fibrillation (POAF)
Interventions: DIETARY_SUPPLEMENT: tart cherry concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reversal of Ketamine Pharmacodynamic Effects With Naloxone
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Saline|DRUG: Saline + Ketamine|DRUG: Naloxone + Placebo|DRUG: Naloxone + Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Caterna Virtual Reality Facilitating Treatment in Children With Amblyopia
Status: UNKNOWN
Conditions: Amblyopia
Interventions: DEVICE: Caterna Virtual Reality|DEVICE: Spectacles(Best optical corrected distance vision)|DEVICE: Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke|Bleeding
Interventions: DRUG: Antiplatelet-only strategy|DRUG: Oral Anticoagulant plus background antiplatelet therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Umbilical Cord Cleansing With a Single Application of 4% Chlorhexidine for the Prevention of Newborn Infections in Uganda: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Omphalitis|Septicaemia
Interventions: BIOLOGICAL: Intervention arm: 4% chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of CNTO 328 in Patients With Metastatic Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: CNTO 328|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Cuff Dehiscence Following Total Laparoscopic Hysterectomy: Laparoscopic vs. Transvaginal Cuff Closure
Status: COMPLETED
Conditions: Surgical Wound Dehiscence
Interventions: PROCEDURE: TRANSVAGINAL SUTURE|PROCEDURE: LAPAROSCOPIC SUTURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Autologous, Hapten-Modified Vaccine in Patients With Stage III or IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: Autologous, DNP-modified vaccine (M-Vax)|BIOLOGICAL: Autologous, DNP-Modified Melanoma Vaccine|BIOLOGICAL: Autologous, DNP-Modified Vaccine|BIOLOGICAL: Autologous, DNP-Modified Vaccine|BIOLOGICAL: Autologous, DNP-Modified Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Modafinil|BEHAVIORAL: Cognitive Behavioral Therapy--Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parallel Versus Perpendicular Technique for Genicular Radiofrequency
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Perpendicular Group|PROCEDURE: Parallel Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fanhdi®, a High-purity Von Willebrand Containing FVIII Concentrate, in Pediatric Patients With Von Willebrand Disease
Status: RECRUITING
Conditions: Von Willebrand Disease
Interventions: DRUG: plasma-derived FVIII/VWF concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemtuzumab Ozogamicin and High-Dose Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: ara-C|BIOLOGICAL: gemtuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter-based Peripheral Regional Anesthesia After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia Strategies After Major Shoulder Ambulatory Surgery
Status: UNKNOWN
Conditions: Tendon Injuries
Interventions: DRUG: Tramadol|DRUG: Nefopam 20 MG/ML|DRUG: Morphine Sulfate|DRUG: Oxycodone 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine Fusion
Status: COMPLETED
Conditions: Spinal Fusion Acquired|Spinal Stenosis|Lesions of Lumbosacral Intervertebral Disc|Spinal Diseases
Interventions: DRUG: Dexmedetomidine|DRUG: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatocyte Growth Factor to Improve Functioning in PAD
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DRUG: VM202|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Maternal and Perinatal Complications by Enoxaparin in Women With Previous Severe Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Lovenox® (enoxaparin)|DRUG: Aspegic ® (Aspirin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 500 mg IV|DRUG: D,L-lysine acetylsalicylate (Aspirin, BAY81-8781) 250 mg IV|DRUG: Acetylsalicylic acid (Aspirin, BAYe4465) 300 mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT