pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Tolerability of Oral Polyethylene Glycol (PEG 3350) Solution in Participants With Constipation (MK-8114-003)
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Polyethylene Glycol (PEG 3350)|DRUG: Placebo|DRUG: Bisacodyl laxative tablets (rescue medication)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypothermic Versus Normothermic Cardiac Bypass in Patients Undergoing CABG Surgery, Effect on Coagulation; Randomized Controlled Trial
Status: COMPLETED
Conditions: CABG Surgery, Cold Blood Cardioplegia, Coagulation Profile and Platelet Function
Interventions: PROCEDURE: Normothermic group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Endothelial Function Guided Therapy in Patients With Non-obstructive Coronary Artery Disease
Status: UNKNOWN
Conditions: Non-obstructive Coronary Artery Disease
Interventions: OTHER: Endothelial function guided therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Performance and Wear Resistance of Two Nano Ceramic Resin Composite in Class I Cavities
Status: UNKNOWN
Conditions: Class I Dental Caries
Interventions: OTHER: Ceram•X (Dentsply De Trey GmbH, Konstanz, Germany|OTHER: Zenit Nano Ceramic Composite (PRESIDENT DENTAL, GmbH, Munich, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Low Back Pain and Meditation
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Mindfulness|DRUG: Naloxone|OTHER: Saline|BEHAVIORAL: Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Different Methods of Nasogastric Tube Insertion in Anesthetized and Intubated Patients
Status: COMPLETED
Conditions: Disorder of Abdomen
Interventions: PROCEDURE: conventional technique|PROCEDURE: head in the lateral position technique|PROCEDURE: endotracheal tube assisted technique|PROCEDURE: videolaryngoscope technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Efficacy of a Turmeric Extract (Arantal®) in Patients With Osteoarthritis of the Knee (Gonarthrosis).
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Arantal® (highly bioavailable turmeric extract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction of Migraine Aura With Cilostazol
Status: COMPLETED
Conditions: Migraine With Aura|Stroke
Interventions: DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Cholecystitis; Acute, With Cholelithiasis
Interventions: DRUG: 1gr oral ampicillin/sulbactam group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Protocol for the Role of Fractional CO2 Laser in Consolidation Treatment of Recurrent Vulvovaginal Candidiasis
Status: UNKNOWN
Conditions: Vulvovaginal Candidiasis, Genital|Laser Therapy
Interventions: RADIATION: the fractional CO2 laser|DRUG: Clotrimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hepatectomy and Local Ablation for Resectable Synchronous and Metachronous Colorectal Liver Metastasis
Status: RECRUITING
Conditions: Secondary Malignant Neoplasm of Liver
Interventions: PROCEDURE: CRLM resection group|DEVICE: CRLM ablation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib Hydrochloride Capsules in Subjects With Diffuse Large B-Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Anlotinib Hydrochloride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors
Status: TERMINATED
Conditions: Small Cell Lung Cancer|Non-small Cell Lung Cancer, Squamous|Non-small Cell Lung Cancer, Non-squamous|Head and Neck Squamous Cell Carcinoma|Esophageal Squamous Cell Carcinoma|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Prostate Cancer|Melanoma
Interventions: DRUG: ladiratuzumab vedotin|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Plus Bortezomib Plus Dexamethasone in Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bendamustine plus bortezomib plus dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Levels, Safety, and Tolerability of BMS-986278 in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986278|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intralymphatic Immunotherapy
Status: COMPLETED
Conditions: Allergy|Immune Tolerance|Injection Site Discomfort
Interventions: DRUG: Alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml.|DRUG: alk (225) Phleum Pratense. 0.1 ml of 10,000 standard quantity units/ml.|DRUG: 0.1 ml Isoton saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Topiramate as "Add on" Treatment in Epilepsy Patients With Primary Generalized Tonic-clonic Seizures
Status: COMPLETED
Conditions: Epilepsy|Seizures
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Tolerance, Safety, and Pharmacokinetics of GNR-055 in Healthy Volunteers
Status: COMPLETED
Conditions: Mucopolysaccharidosis Type II|Metabolic Diseases
Interventions: BIOLOGICAL: verenafusp alfa 6 mg/kg|BIOLOGICAL: verenafusp alfa 9 mg/kg|BIOLOGICAL: verenafusp alfa 12 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Improve Deployment Related Asthma by Using L-Citrulline Supplementation
Status: RECRUITING
Conditions: Post Deployment Related Asthma|Asthma
Interventions: DRUG: L-citrulline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of TU and MRT to Release Trigger Points to Increase RoM and Pain Relief in Upper TT
Status: ENROLLING_BY_INVITATION
Conditions: Pain
Interventions: DIAGNOSTIC_TEST: Therapeutic Ultrasound|DIAGNOSTIC_TEST: Myofascial Release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TAP Blocks With Ropivacaine Continuous Infusion Catheters vs Single Dose Liposomal Bupivicaine After Kidney Transplant
Status: RECRUITING
Conditions: Transplant;Failure,Kidney|Pain, Postoperative
Interventions: DRUG: Ropivacaine Continuous Infusion Catheter|DRUG: Single Dose Liposomal Bupivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Muscle Activity on Subjective Tinnitus in Temporomandibular Disorders
Status: COMPLETED
Conditions: Tinnitus, Subjective|Temporomandibular Disorder
Interventions: PROCEDURE: Occlusal Splint Treatment- Non Invasive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the CardioFocus Endoscopic Ablation System - Adaptive Contact (EAS-AC) for the Treatment of Symptomatic Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: CardioFocus HeartLight Endoscopic Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅰ/Ⅱ Clinical Study to Evaluate ABO2011 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: ABO2011 Injection|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and ABVD for Hodgkin's Patients
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Rituximab|DRUG: Adriamycin|DRUG: Bleomycin|DRUG: Vinblastine|DRUG: Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis
Status: NOT_YET_RECRUITING
Conditions: Bronchiectasis
Interventions: DRUG: Antibiotic monotherapy treatment and follow-up|DRUG: Antibiotic bitherapy treatment and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Education Before Orthognathic Surgery
Status: COMPLETED
Conditions: Malocclusion|Anxiety|Micrognathism|Prognathism
Interventions: OTHER: Booklet - Preoperative Educational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Self-contamination Following Removal of Two Personal Protective Equipment Suits: a Crossover Trial
Status: COMPLETED
Conditions: Personal Protective Equipment|Self Contamination
Interventions: OTHER: Gown personal protective equipment (PPE-G) suit|OTHER: Coverall personal protective equipment (PPE-C) suit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Postoperative QoR-15 Scores Between Propofol and Remimazolam
Status: COMPLETED
Conditions: Patients Undergoing Spine Surgery
Interventions: DRUG: Propfol group|DRUG: Remimazolam group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fixation of OsseoTi™ Porous Structure Versus PPS (Porous Plasma Spray) Coating on the G7™ Acetabular Component for Primary Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: THA with G7 PPS coted acetabular component|DEVICE: THA with G7 OsseoTi coted acetabular component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Pain After Hernial Sac Ligation Versus Non-ligation in Inguinal Hernioplasty
Status: COMPLETED
Conditions: Inguinal Hernia, Indirect|Postoperative Pain
Interventions: PROCEDURE: Ligation of indirect hernia sac|PROCEDURE: Non-ligation of Indirect Inguinal hernia sac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain
Status: RECRUITING
Conditions: Chronic Musculoskeletal Pain
Interventions: BEHAVIORAL: Emotional Awareness and Expression Therapy|BEHAVIORAL: Mindfulness Meditation|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study
Status: COMPLETED
Conditions: Sinus Floor Augmentation|Maxillary Sinus
Interventions: PROCEDURE: Calcium phosphosilicate alloplastic bone putty in direct sinus augmentation|PROCEDURE: Anorganic bovine bone mineral in direct sinus augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous/Nonmalignant Condition|Small Intestine Cancer
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: filgrastim|DRUG: cladribine|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: methylprednisolone|DRUG: tacrolimus|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: T Cell Phenotypes in Amyotropic Lateral Sclerosis (ALS), Influence of Vitamin D
Status: COMPLETED
Conditions: ALS
Interventions: OTHER: phenotyping Tcells|OTHER: Supplementation in vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Oral Sucrose in Reducing the Pain to Orogastric Tube Insertion in Preterm Neonates
Status: COMPLETED
Conditions: Pain in Preterm Neonates
Interventions: DRUG: Sucrose|DRUG: Double distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open, Randomized Crossover Study on PK, PD, Biopotency, and Bioavailability of Insulin Capsules in Healthy Chinese Males
Status: NOT_YET_RECRUITING
Conditions: Diabete Mellitus
Interventions: DRUG: Human insulin enteric coated capsules in dose 16mg|DRUG: Human insulin enteric coated capsules in dose 8mg|DRUG: Human Insulin Injection in dose 5IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Resin Composite Restoration of Primary Anterior Teeth Using Custom 3D Printed Templates
Status: COMPLETED
Conditions: Primary Teeth
Interventions: OTHER: Direct composite restoration of carious primary anterior teeth using custom 3D printed templates|OTHER: Direct composite restoration of carious primary anterior teeth using conventional strip crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Bacterial Pneumonia
Interventions: DRUG: Ceftaroline fosamil for Injection|DRUG: IV Ceftriaxone|DRUG: Placebo|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FrActional Flow Reserve Guided Drug Coated Balloon Only Strategy in De Novo coronarY Lesions (FADDY)
Status: UNKNOWN
Conditions: Coronary Stenosis
Interventions: DEVICE: Drug-coated balloon|DEVICE: Drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single and Repeated Dose of Vaginal Misoprostol for the Treatment of Early Pregnancy Failure
Status: COMPLETED
Conditions: Abortion, Missed
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role PET Imaging in Response Assessment for Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Primary Liver Cancer
Interventions: PROCEDURE: MRI of the liver before start of treatment|PROCEDURE: MRI after treatment|PROCEDURE: PET-scan before treatment start|PROCEDURE: PET scan after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection After Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: PROCEDURE: transcruciate injection of 20cc of normal saline|PROCEDURE: transcruciate injection of 20 cc of 0.5% Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Physical Activity Intervention to Promote Physical Activity
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: PATH Intervention|BEHAVIORAL: Attention Control Intervention|OTHER: Physical activity tracker|BEHAVIORAL: Dietary education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Core Stabilization Exercises vs. Schroth's Program on Posture and Quality of Life in Females With Scoliosis.
Status: COMPLETED
Conditions: Scoliosis Idiopathic
Interventions: OTHER: Core stability exercise|OTHER: Scroth's Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triapine and Gemcitabine Hydrochloride in Gallbladder Cancer
Status: COMPLETED
Conditions: Stage II Gallbladder Cancer|Stage IIIA Gallbladder Cancer|Stage IIIB Gallbladder Cancer|Stage IVA Gallbladder Cancer|Stage IVB Gallbladder Cancer
Interventions: DRUG: triapine|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers
Status: COMPLETED
Conditions: Hepatitis C|HIV
Interventions: DRUG: boceprevir; etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: DBS for Treatment Resistant Depression
Status: COMPLETED
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: DEVICE: deep brain stimulation with short & long pulse width
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Verification of XAPPORT: a Decision Support App for Physicians Used for Patients Anticoagulated With Rivaroxaban in Terms of Anticoagulation Management in Elective Surgery: Verification Process of Medical Decision Algorithm
Status: WITHDRAWN
Conditions: Atrial Fibrillation|Venous Thromboembolism|Pulmonary Embolism
Interventions: OTHER: XAPPORT|OTHER: Expert Panel ("gold standard")
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of AMG 820 in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Malignancy|Advanced Solid Tumors|Cancer|Oncology|Oncology Patients|Tumors
Interventions: DRUG: AMG 820
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Benign Uterine Disorders Using High Intensity Focused Ultrasound (MR-HIFU)
Status: RECRUITING
Conditions: Uterine Fibroids|Adenomyosis
Interventions: DEVICE: MRI-HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stability of Bimaxillary Proclination Cases Following Fixed Appliances Treatment: A Randomized Control Trial
Status: UNKNOWN
Conditions: Bimaxillary Proclination
Interventions: OTHER: Vacuum formed retainer, fixed bonded retainer, vacuum formed and fixed bonded retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Mood Disorders|Sleep Disorders
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Supportive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: STOP Heart Disease in Breast Cancer Survivors Trial
Status: TERMINATED
Conditions: Breast Cancer|Heart Disease|Cardiotoxicity|Myocardial Dysfunction
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Safety and Resulting Blood Level Profiles After Administration of a New Boceprevir Tablet Versus Its Current Capsule Formulation for Treatment of Chronic Hepatitis C (P06992)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: boceprevir|DRUG: boceprevir|DRUG: boceprevir|DRUG: boceprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Adhesiveness of 2 Different Rotigotine Patches Used for the Treatment of Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine (Test product PR 2.3.1)|DRUG: Rotigotine (Reference product PR 2.1.1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of "Multi-Psychological Empowerment" Courses
Status: NOT_YET_RECRUITING
Conditions: Cancer|Oncology|Psychological|Self Efficacy|Communication
Interventions: OTHER: Multi-Psychological Empowerment Courses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: the Role of Two Different Metronomic Chemotherapy Regimens in Locally Advanced or Metastatic Triple Negative Breast Cancer Patients (TNBC) as Maintenance Therapy After First Line Treatment
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Vinorelbine Tartrate|DRUG: Capecitabine 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Vitamin B12 and Folic Acid on POCD in Elderly Non-cardiac Surgical Patients
Status: TERMINATED
Conditions: Post Operative Cognitive Dysfunction
Interventions: DRUG: methylcobalamin|DRUG: Folic Acid|OTHER: Placebo for methylcobalamin|OTHER: Placebo for folic acid|PROCEDURE: non-cardiac surgery|BEHAVIORAL: NPB test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Metacognitive Training for Negative Symptoms
Status: RECRUITING
Conditions: Negative Symptoms in Schizophrenia
Interventions: OTHER: Metacognitive Training for Negative Symptoms (MCT)|OTHER: Supportive Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: corifollitropin alfa|DRUG: Follitropin Beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1:27-35 peptide vaccine|BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: therapeutic autologous lymphocytes|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Enhanced Recovery After Surgery (ERAS) for Cesarean Section on Neonatal Blood Glucose
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery|Cesarean Section
Interventions: DIETARY_SUPPLEMENT: Carbohydrate Preoperative Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Drug Treatment for Depressed Alcoholics (Naltrexone/Fluoxetine)
Status: COMPLETED
Conditions: Alcoholism|Alcohol Dependence|Depression
Interventions: DRUG: naltrexone (Revia)|DRUG: fluoxetine (Prozac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Sitagliptin in Older Type 2 Diabetics (0431-047)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: sitagliptin phosphate|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Written Exposure Therapy for Veterans With SUD and PTSD
Status: RECRUITING
Conditions: Substance Use Disorders|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Written Exposure Therapy|BEHAVIORAL: Neutral Topic Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation
Status: RECRUITING
Conditions: Surgery--Complications
Interventions: PROCEDURE: Small stitch|OTHER: Blood sample|OTHER: Tissue Sample|OTHER: Pain Score|OTHER: Quality of Life Score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Non-surgical Integrative Package on Failed Back Surgery Syndrome
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DRUG: Chuna herbal medicine|PROCEDURE: Chuna manual therapy|PROCEDURE: Acupuncture|PROCEDURE: Bee-venom pharmacoacupuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Carbamazepine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Catheter Location Relative to Femoral Artery on Postoperative Analgesia for Continuous Adductor Canal Blocks
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Above Artery Catheter Placement|PROCEDURE: Between Artery and Vein Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program
Status: COMPLETED
Conditions: Lung Diseases|Medication Compliance
Interventions: DRUG: Fluticasone propionate 230mcg for 3 Months|DRUG: Current Treatment or no treatment|DRUG: Salmeterol 21mcg for 3 Months
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Serum Vitamin D Levels and Musculoskeletal Adverse Effects in Patients Using Isotretinoin
Status: COMPLETED
Conditions: Musculoskeletal Disease Other|Isotretinoin Adverse Reaction|Vitamin D Deficiency
Interventions: DRUG: Isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effects of Breakfast on Neuropsychological Functioning
Status: COMPLETED
Conditions: Neuropsychology
Interventions: OTHER: Nutella Breakfast|OTHER: Waffle Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Disc Disease|Spinal Fusion
Interventions: COMBINATION_PRODUCT: TGplPTH1-34 in fibrin|OTHER: Autologous Bone Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Substitution Therapy in Patients With Central Diabetes Insipidus
Status: RECRUITING
Conditions: Central Diabetes Insipidus (cDI)
Interventions: DRUG: Intranasal OXT|OTHER: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy
Status: RECRUITING
Conditions: Infertility|Infertility, Female|Infertility, Male|Infertility Unexplained
Interventions: PROCEDURE: arteficial inteligence evaluation of oocyte and embryo development
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Bimodal Solution for Peritoneal Dialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: bimodal solution|DRUG: icodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dalutrafusp Alfa (Formerly GS-1423) in Participants With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Dalutrafusp alfa|DRUG: mFOLFOX6 Regimen|DRUG: Dalutrafusp alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab vedotin|DRUG: Doxorubicin Hydrochloride|DRUG: Pembrolizumab|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Large-scale Networks in Depression With Real-time fMRI (Functional Magnetic Resonance Imaging) Neurofeedback
Status: RECRUITING
Conditions: Healthy Participants
Interventions: OTHER: Functional magnetic resonance imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supplementation of Lycopene in Carotid Atheroma
Status: WITHDRAWN
Conditions: Carotid Atherosclerotic Disease
Interventions: DRUG: Placebo|DIETARY_SUPPLEMENT: Ateronon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 18FluoroLDOPA PET Imaging for the Detection and Localization of Focal Congenital Hyperinsulinism
Status: RECRUITING
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: 18F-Fluoro Dopa Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Two Year Safety and Efficacy Study in Obese Patients (0364-015)(TERMINATED)
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: taranabant|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Transplantectomy Versus Conventional Care After Kidney Graft Failure
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: PROCEDURE: Systematic transplantectomy|PROCEDURE: Progressive reduction of immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Methylnaltrexone on GI Transit in Healthy Volunteers
Status: COMPLETED
Conditions: Gastric Motility Disorder
Interventions: DRUG: Methylnaltrexone only|DRUG: Codeine only|DRUG: Methylnaltrexone + codeine|DRUG: Placebo + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study Comparing Aspirin and Aspirin Granules
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAY1019036)|DRUG: Acetylsalicylic acid (Aspirin, BAY1019036)|DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)|DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastases
Interventions: DRUG: Efaproxiral|RADIATION: Whole Brain Radiation Therapy (WBRT)|OTHER: Supplemental Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mobile Apps for Informal Caregivers of People Living With Dementia
Status: COMPLETED
Conditions: Caregiver Burden|Stress|Dementia
Interventions: OTHER: Dementia Talk mobile application|OTHER: CLEAR Dementia Care mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Electrophysiological Markers of Antidepressants in Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Electroretinography (ERG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Labour Pain and Birth-Specific Stereogram Cards (BSSC)
Status: COMPLETED
Conditions: Labor Pain|Birth, First
Interventions: OTHER: Birth-Specific Stereogram Cards (BSSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery
Status: RECRUITING
Conditions: Transcranial Electrical Stimulation
Interventions: DEVICE: Transcranial electrostimulation (TES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Liquid Flavor and Nicotine Form Outcomes
Status: COMPLETED
Conditions: Electronic Cigarettes
Interventions: OTHER: E-cigarette with sweetness type 1 and pronation level 1|OTHER: E-cigarette with sweetness type 1 and pronation level 2|OTHER: E-cigarette with sweetness type 2 and pronation level 1|OTHER: E-cigarette with sweetness type 2 and pronation level 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Adding TCM-700C on the Standard Combination Treatment for Patients With Genotype 1 Hepatitis C Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: TCM-700C|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AZD 8529|DRUG: Risperidone|DRUG: Placebo to match AZD8529|DRUG: Placebo to match risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Hamstring Injuries in Football Players.
Status: COMPLETED
Conditions: Hamstring Injuries
Interventions: OTHER: Passive Neurodynamics and Passive axial hip mobilisation/distraction|OTHER: Active therapy|OTHER: 2.5.3. Combined therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hallux Valgus Correction Using the Metal Screw or the Human Allogeneic Cortical Bone Screw (Shark Screw).
Status: NOT_YET_RECRUITING
Conditions: Hallux Valgus
Interventions: PROCEDURE: Hallux Valgus Treatment with Shark Screw®|PROCEDURE: Hallux Valgus Treatment with metal screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sbrt±sTad for Unfavorable iNtermediate rIsk/High Risk Prostate caNcer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Decapeptyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Bio-Oss Collagen for Sinus Augmentation Using the Transcrestal Approach.
Status: RECRUITING
Conditions: Bone Loss|Missing Teeth
Interventions: DEVICE: Geistlich Bio-Oss® Collagen|DEVICE: Geistlich Bio-Oss® Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing Kids for Liver Inflammation and Fibrosis Using Non-invasive MRI
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis|Liver Diseases|Liver Fibroses|Autoimmune Hepatitis|Liver Cirrhoses
Interventions: DEVICE: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antibiotic Stewardship and Infection Control in Patients at High Risk of Developing Infection by Clostridium Difficile, Vancomycin-Resistant Enterococci or Multi-Resistant Gram-Negatives
Status: COMPLETED
Conditions: Clostridium Difficile Infection|VRE Infection|Nosocomial Infection|MRGN Bacteria
Interventions: OTHER: Infection Control|OTHER: Antibiotic Stewardship
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREMAPROB. Probiotics to Prevent Necrotizing Enterocolitis
Status: COMPLETED
Conditions: Premature Infants|Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: High dose group|DIETARY_SUPPLEMENT: Low dose group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hypoglycaemia on Brain Lactate Accumulation and Cerebral Blood Flow
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia Unawareness
Interventions: OTHER: hypoglycemia|OTHER: euglycemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis|Chronic Kidney Diseases
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Standard maintenance therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Treatments for Acute Rotator Cuff Tendinopathy
Status: COMPLETED
Conditions: Acute Rotator Cuff Tendinopathy
Interventions: BEHAVIORAL: Gradual reloading|BEHAVIORAL: Rest and cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vistakon Investigational Lens Worn as a Single Use Daily Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: narafilcon B|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 3 Lots of Cell-derived Subunit Influenza Vaccine as Compared to 1 Lot to Egg-derived Subunit Influenza Vaccine in Healthy Adults (>=18 to <=60)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell-Derived Trivalent Subunit Influenza Vaccine Lot 1 (cTIV)|BIOLOGICAL: Cell-Derived Trivalent Subunit Influenza Vaccine Lot 2 (cTIV)|BIOLOGICAL: Cell-Derived Trivalent Subunit Influenza Vaccine Lot 3 (cTIV)|BIOLOGICAL: Egg-Derived Trivalent Subunit Influenza Vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Detection Rates of 50 Gr-100 Gr OGTT and 75 Gr OGTT That Require Medical Treatment of GDM
Status: RECRUITING
Conditions: Gestational Diabetes|Glucose Intolerance During Pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CoHort of Patients to Identify Biological and Imaging markerS of CardiovascUlar Outcomes in Stroke - HIBISCUS-STROKE II
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: OTHER: Collection of blood samples and MRI imaging in order to create a bio- and imaging-collection|OTHER: Cardiac MRI with gadolinium injection - Ancillary Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Postdural Puncture Headache Relief With Aminophylline and SPGB
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: conservative therapy|DRUG: Aminophylline|PROCEDURE: trans nasal sphenopalatine ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Adagio Cryoablation System in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DEVICE: Cryoablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With SHR-1210 as Second-line Treatment in Solid Tumors With Only Liver Metastases
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: Apatinib and Camrelizumab for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Immunogenicity of 2 Subcutaneous Doses of CHS-1701 (Coherus Pegfilgrastim) With 2 Subcutaneous Doses Neulasta®
Status: COMPLETED
Conditions: Immunity, Humoral
Interventions: DRUG: CHS-1701|DRUG: Pegfilgrastim (Neulasta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: 4D CBCT and Intrafractional Imaging for the Determination of the Most Representative 4D Simulation Planning Technique for Lung SBRT Technique Patients
Status: COMPLETED
Conditions: Cancer of Lung
Interventions: OTHER: AIP CT|OTHER: FB (Free-Breathing) CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Day 3 Embryo Biopsy Versus Blastocyst Biopsy in PGS Cases
Status: WITHDRAWN
Conditions: Infertility|Embryo Biopsy
Interventions: OTHER: Day 3 embryo biopsy|OTHER: Blastocyst biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER