pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of microMend® Devices to Sutures in Closing Lacerations in Children
Status: UNKNOWN
Conditions: Laceration|Skin Wound|Wound Heal
Interventions: DEVICE: microMend®|DEVICE: Closure with Sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SKIPPAIN - Speed of Onset of SecuKinumab-Induced Relief From Pain in Patients With AxIal SpoNdyloarthritis
Status: COMPLETED
Conditions: Spondyloarthritis
Interventions: BIOLOGICAL: AIN457|DRUG: AIN457 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel in Combination With Carboplatin Versus Paclitaxel Plus Epirubicin in Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel, Carboplatin|DRUG: Paclitaxel, Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Trastuzumab Administered as a Single Intravenous Infusion
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Hercules|BIOLOGICAL: Herceptin EU|BIOLOGICAL: Herceptin US
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Combination of Antibiotics to Decrease Neonatal Morbidity and Mortality for Previable Threatened Labor
Status: NOT_YET_RECRUITING
Conditions: Previable Labour With Intact Membranes
Interventions: DRUG: Combination of antibiotics|DEVICE: Emergency cerclage|DRUG: Vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fenoldopam to Prevent Renal Dysfunction in Indomethacin Treated Preterm Infants
Status: TERMINATED
Conditions: Patent Ductus Arteriosus (PDA)|Acute Kidney Injury (AKI)
Interventions: DRUG: Fenoldopam|DRUG: 0.9%NS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Secretin in Functional Dyspepsia and Healthy Subjects
Status: COMPLETED
Conditions: Dyspepsia|Healthy
Interventions: DRUG: Human Secretin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing in Women's Pelvic Wellness Education
Status: COMPLETED
Conditions: Pelvic Floor Disorders|Urinary Incontinence (UI)|Pelvic Prolapse Conditions
Interventions: BEHAVIORAL: Workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trials of Vitamin Supplements and Eye Disease
Status: UNKNOWN
Conditions: Macular Degeneration|Cataract
Interventions: DRUG: Aspirin|DRUG: Beta-Carotene|DRUG: Vitamin C|DRUG: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Solid Tumor|Soft Tissue Sarcoma|Metastatic Sarcoma|Sarcoma
Interventions: DRUG: NC 6300
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-1006 Single Dose Study in Japanese Type 2 Diabetes Patients (MK-1006-005)
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: MK-1006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oxaliplatin Plus Bevacizumab in Germ Cell Tumor Patients
Status: COMPLETED
Conditions: Neoplasms, Germ Cell and Embryonal
Interventions: DRUG: Bevacizumab and Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-99712, a BCMA Antibody-Drug Conjugate, in Participants With Relapsed and Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: CC-99712|DRUG: BMS-986405
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Corneal Endothelial Health of DED Subjects Treated With Cyclosporine
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Disease
Interventions: DRUG: Cyclosporine ophthalmic solution, 0.1%|DRUG: Saline solution, 0.6%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Botanicals for Mechanisms Related to Appetite and Fat Metabolism
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Apple|DIETARY_SUPPLEMENT: Grape|DIETARY_SUPPLEMENT: Raspberry|DIETARY_SUPPLEMENT: Apricot/Nectarine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Supraclavicular Brachial Plexus Blocks at Various Volumes: Impact on Optic Nerve Sheath Diameter
Status: RECRUITING
Conditions: Upper Limb Injury|Intracranial Pressure Increase
Interventions: PROCEDURE: Supraclavicular brachial plexus block|DEVICE: Measurement of Optic Nerve Sheath Diameter (ONSD) Using B-Mode Ultrasound|DEVICE: Assessment of Peripheral Nerve Block Success Using Perfusion Index Measurement|DEVICE: End-Tidal Carbon Dioxide (EtCO2) Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest
Status: COMPLETED
Conditions: Cardio Respiratory Arrest
Interventions: OTHER: Therapeutic hypothermia|DEVICE: Synchronized Intermittent Mandatory Ventilation|OTHER: Electroencephalography|DEVICE: Pupillary light reflex surveillance|DEVICE: Transcranial Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Management of Newly Diagnosed and Uncontrolled Hypertension With Fixed-Dose Combination of Perindopril/Amlodipine and Perindopril/Indapamide/Amlodipine
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlessa®|DRUG: Co-Amlessa®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUropean Pharmacogenetics of AntiCoagulant Therapy - Acenocoumarol
Status: COMPLETED
Conditions: Venous Thromboembolism|Atrial Fibrillation
Interventions: OTHER: Genotype-guided dosing algorithm|OTHER: Non-genotype-guided dosing algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Respiratory Depression in Women With BMI≥30 Underwent Spinal Anesthesia With Intrathecal Morphine in Elective C-section
Status: UNKNOWN
Conditions: Respiratory Depression
Interventions: DEVICE: SOMNOTOUCH RESP|PROCEDURE: Caesarean section|DRUG: Spinal anesthesia with intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Point-of-Choice Prompts to Reduce Prolonged Sitting Time at Work
Status: COMPLETED
Conditions: Adult Office Workers
Interventions: DEVICE: MyRestBreak 1.0|BEHAVIORAL: education talk and leaflet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Status: RECRUITING
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Exposure-based therapy|BEHAVIORAL: Supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Mepolizumab as an Add-on Treatment in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Mepolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Papillomavirus Infection and Related Anal Lesions in HIV-positive Men Who Have Sex With Men
Status: COMPLETED
Conditions: Hiv Infection
Interventions: PROCEDURE: Standard proctologic examination|PROCEDURE: High resolution anoscopy|PROCEDURE: Biopsy(ies) during High Resolution Anoscopy|PROCEDURE: High Resolution Anoscopy biannually
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Bilastine Tablets in Healthy Chinese Subjects
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Test (T) Bilastine|DRUG: Reference (R) Bilastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactated Ringers With or Without Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
Status: COMPLETED
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Indomethacin|DRUG: Lactated Ringer's Solution|DRUG: Normal Saline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: "One-step" Bone Marrow Mononuclear Cell Transplantation in Talar Osteochondral Lesions
Status: COMPLETED
Conditions: Osteochondritis
Interventions: PROCEDURE: bone marrow cells transplantation on collagen scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATILA Project: Aspirin Versus Tirofiban in Endovascular Treatment for Patients With Acute Ischemic Stroke Due to Tandem Lesion
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Tirofiban|DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Release of Proinflammatory Cytokines (IL-1β, IL-6) and Total-prostaglandin (PG) Following Femtosecond Laser-assisted Cataract Surgery Compared to Manual Cataract Surgery
Status: COMPLETED
Conditions: Age Related Cataracts
Interventions: DEVICE: Femtosecond Laser-assisted|PROCEDURE: Manual Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Phase 2 Trial of the Immunogenicity, and Safety of GI-4000; an Inactivated Recombinant S. Cerevisiae Expressing Mutant Ras Protein, as Consolidation Therapy Following Curative Treatment for Stage I-III Non-Small Cell Lung Cancer (NSCLC) With Tumor Sequence Confirmation of K-ras Mutation
Status: COMPLETED
Conditions: NSCLC
Interventions: BIOLOGICAL: GI-4000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring the Effects of Probiotic Supplementation in Immunocompromised Kidney Transplanted Subjects
Status: WITHDRAWN
Conditions: Diarrhea Caused by Drug|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: Florajen Digestion Supplementation|DIETARY_SUPPLEMENT: Placebo Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Neoadjuvant Hormonal Therapy on the Surgical Management of Extensive Ductal Carcinomas in Situ
Status: RECRUITING
Conditions: Ductal Carcinoma in Situ|Extensive Disease|Mastectomy
Interventions: DRUG: Tamoxifen 20 mg|DRUG: Anastrozole 1Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Adults to Determine the Effect That Food Has on the Absorption and Delivery of the Drug Cystagon™
Status: COMPLETED
Conditions: Cystinosis|Nephropathic Cystinosis
Interventions: DRUG: Cysteamine bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Efficacy of Dexmedetomidine Versus Labetalol In Providing Controlled Hypotension In Dacryocystorhinostomy SurgeryA Comparative Randomized Prospective Study
Status: RECRUITING
Conditions: Nasolacrimal Duct Obstruction
Interventions: DRUG: Dexmedetomidine|DRUG: Labetalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Multi-Center Study To Evaluate The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist In Adults With Type 2 Diabetes And Overt Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: PF-04634817|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Failure and Hemodynamic Stability During Anesthesia Induction
Status: COMPLETED
Conditions: Hemodynamic Instability|Anesthesia; Adverse Effect|Heart Failure|Diastolic Dysfunction|Venous; Return (Anomaly)
Interventions: OTHER: Preoperative colloid fluid bolus (Gelofusine)|DIAGNOSTIC_TEST: Preoperative transthoracic echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Culturally Adapted Cognitive Behavioral Intervention Among COVID-19 Survivors
Status: COMPLETED
Conditions: Psychological Distress|Quality of Life|Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: Culturally Adapted Cognitive Behavioral Intervention (CA-CBI)|OTHER: Enhanced Treatment as Usual (ETA-U)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Lipid Microsphere (DT-LM) for Injection in Chemotherapy Patients
Status: UNKNOWN
Conditions: Advanced Cancer
Interventions: DRUG: DT-LM|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Corporal Visualisation Program of the Static and Dynamic Balance After an Operation of the LCA
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Interventions: OTHER: Motor Imagery Program|OTHER: Placebo program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
Status: COMPLETED
Conditions: Bone Infection|Osteomyelitis|Septic Arthritis|Joint Infection|Prosthetic Joint Infection
Interventions: DRUG: Dalbavancin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Fecal Flora Alteration for Eradication of Carbapenemase-producing Enterobacteriaceae Colonization
Status: SUSPENDED
Conditions: Infection
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Retapamulin in Pediatric Subjects With Uncomplicated Skin Infections.
Status: COMPLETED
Conditions: Skin Infections, Bacterial
Interventions: DRUG: Retapamulin Ointment, 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectivity of Quadratus Lumborum Blocks With Adjuvant
Status: COMPLETED
Conditions: Postoperative Pain Management|Postoperative Pain|Analgesia|Nerve Blocks|Nerve Block Duration|Cholecystectomy
Interventions: PROCEDURE: Adjuvant-free Quadratus lumborum block|PROCEDURE: Quadratus lumborum block III with Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CAR-T Cell Immunotherapy for EphA2 Positive Malignant Glioma Patients
Status: WITHDRAWN
Conditions: EphA2 Positive Malignant Glioma|CAR-T Cell Immunotherapy
Interventions: BIOLOGICAL: CAR-T cell immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Bioavailability of JNJ-47910382 Formulated as a Tablet and as Suspension in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: JNJ-47910382 (suspension)|DRUG: JNJ-47910382 (tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-intensity vs. Low-intensity Inspiratory Muscle Training in Patients With Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: High-intensity IMT + Aerobic/resistance exercise|OTHER: Low-intensity IMT + Aerobic/resistance exercise|OTHER: Sham IMT + Aerobic/resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin for Uncontrolled Asthma
Status: COMPLETED
Conditions: Uncontrolled Asthma
Interventions: DRUG: Aspirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bacille Calmette Guerin (BCG) Revaccination of Healthy Adolescents for the Prevention of Mycobacterium Tuberculosis Sustained Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BCG vaccine SSI|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: ANX007|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School Partnered Collaborative Care (SPACE) Intervention for Children With Type 1 Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: SPACE for T1D|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Two Doses of Coenzyme Q10 on Seminal Fluid and Semen Antioxidant Status
Status: COMPLETED
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10 200|DIETARY_SUPPLEMENT: Coenzyme Q10 400
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Ultrasound-Assisted Debridement to Influence Wound Healing
Status: COMPLETED
Conditions: WOUNDS
Interventions: DEVICE: Ultrasound debridement|DEVICE: Best practice wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19-CAR-T Cells in Relapsed/Refractory B-cell Tumor Patients.
Status: RECRUITING
Conditions: B Cell Malignancies
Interventions: BIOLOGICAL: anti-CD19-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Happy Mother - Healthy Baby: Supplement Study on Biological Processes Underlying Anxiety During Pregnancy
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT) for anxiety during pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Humor Therapy and Distress After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: BEHAVIORAL: Humor therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Cognitive Decline
Interventions: DRUG: Resveratrol, Quercetin, and Curcumin (RQC)|DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Saline for Myofascial Pain Syndromes (USAMPS)
Status: TERMINATED
Conditions: Myofascial Pain Syndrome
Interventions: DRUG: Normal Saline|DRUG: Lidocaine Hydrochloride|DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Term Evaluation of the Soothing and Re-epithelizing Activity of Three Topical Products and Relative Combinations
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: plantaricin a - rejuvenating cream|OTHER: plantaricin a - antioxidant serum|OTHER: plantaricin a - rejuvenating serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Cortisol in Chronic Posttraumatic Stress Disorder
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Cortisol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers
Status: RECRUITING
Conditions: Hepatitis|Pharmacology
Interventions: DRUG: Panadol®|DRUG: SafeTynadol®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection
Status: RECRUITING
Conditions: Rectum Cancer
Interventions: PROCEDURE: Closure of the pelvic peritoneum|PROCEDURE: Nonclosure of the pelvic peritoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.
Status: RECRUITING
Conditions: Diabetes Mellitus|Dysglycemia|Perioperative Complication
Interventions: DEVICE: Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Injection for Preventing Secondary Atrial Fibrillation in Patient With Supra-ventricular Tachyarrythmias
Status: UNKNOWN
Conditions: Supra-ventricular Tachyarrhythmias
Interventions: PROCEDURE: radiofrequency ablation|DRUG: botulinum toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota Transplantation for Radiation Enteritis
Status: UNKNOWN
Conditions: Radiation Enteritis
Interventions: PROCEDURE: Selective Microbiota Transplantation (SMT)|PROCEDURE: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of IV/PO Moxifloxacin in Subjects With Community-acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Ceftriaxone; Azithromycin; Amoxicilline/clavulanate; Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADvance DBS-f in Patients With Mild Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DEVICE: DBS-f on|DEVICE: DBS-f off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel, Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cetuximab|DRUG: cisplatin|RADIATION: intensity-modulated radiation therapy|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rituximab in Pediatric OMS Patients.
Status: COMPLETED
Conditions: Opsoclonus-myoclonus Syndrome|Opsoclonus|Myoclonus|Ataxia
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Prognostic Value of Sarcopenia in Patients Older Than 70 Years With Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma|Grade IIIB Follicular Lymphoma
Interventions: PROCEDURE: anthropometric measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Heterotopic Ossification in Abdominal Incision and Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer of Pancreas|Ossification, Heterotopic
Interventions: DIAGNOSTIC_TEST: Bone alkaline phosphatase|RADIATION: Abdominal CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lumbar Plexus-sciatic Nerve Block With Sevoflurane on Cognitive Function in Elderly Patients After Hip Arthroplasty
Status: UNKNOWN
Conditions: Hip Arthropathy
Interventions: DRUG: sevoflurane inhalation for anesthesia|DRUG: propofol for anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neurotoxicity|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Short Treatment Study of Aripiprazole in Pediatric Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole Low (2 mg/day)|DRUG: Aripiprazole Mid (6 - 12 mg/day)|DRUG: Aripiprazole High (24 - 30 mg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Obstructive Pulmonary Disease (COPD)-Related Healthcare Utilization and Costs After Discharge From a Hospitalization or Emergency Department Visit on a Regimen of Fluticasone Propionate-Salmeterol Combination Versus Other Maintenance Therapies
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol xinafoate combination|DRUG: Other maintenance Treatments (OMT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Lapatinib Plus Nab-Paclitaxel As First And Second Line Therapy In her2+ MBC
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib/nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Occurrence of HPA-1a Alloimmunization in Women With Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia
Status: RECRUITING
Conditions: Fetal and Neonatal Alloimmune Thrombocytopenia
Interventions: OTHER: Clinical data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DEVICE: Home-based leg heat therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluate the Effectiveness of Self-care Multifaceted Strategy in Heart Failure Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Multifaceted strategy based on sending text messages(SMS)|OTHER: Usual outpatient care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of ASCT and Conventional Chemotherapy in High Risk Waldenström Macroglobulinemia
Status: UNKNOWN
Conditions: Waldenström Macroglobulinemia
Interventions: OTHER: autologous stem cell transplantation|OTHER: conventional chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Followed by Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: in vitro-treated bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Is Osteopathic Manipulative Treatment (OMT) Beneficial for Elderly Patients Hospitalized With Pneumonia?
Status: COMPLETED
Conditions: Pneumonia
Interventions: PROCEDURE: Osteopathic Manipulative Treatment|PROCEDURE: Light-touch Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Sustained Low Efficiency Dialysis in Critically Ill Cirrhotics With Septic Shock and Acute Kidney Injury
Status: UNKNOWN
Conditions: Cirrhotics With Septic Shock and Acute Kidney Injury
Interventions: BIOLOGICAL: Early SLED|BIOLOGICAL: Late SLED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Myofascial Release Techniques on Iliotibial Band Tightness
Status: COMPLETED
Conditions: Fascia Lata
Interventions: OTHER: Self Myofascial Relaxation|OTHER: Instrument Assisted Soft Tissue Mobilization|OTHER: Only Exercise (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Upper Limb Motor and Robotic Training Over Neuroplasticity and Function Capacity
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: Robotic occupational therapy|PROCEDURE: Induced Constraint Therapy - ICT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Network-Level Mechanisms for Preclinical Alzheimer's Disease Development
Status: COMPLETED
Conditions: APOE 4
Interventions: DRUG: AGB101 220 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cost/Utility Ratio in the Management of Patients With Acquired Severe Brain Injury
Status: COMPLETED
Conditions: Nervous System Diseases
Interventions: OTHER: multidisciplinary intervention|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of a Novel Dietary Intervention on Body Composition After Laparoscopic Gastric Bypass Surgery
Status: TERMINATED
Conditions: Obesity|Morbid Obesity
Interventions: DIETARY_SUPPLEMENT: BariatrX Essentials 360 Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Etanercept 50 MG/ML|DRUG: Leflunomide 10 milligram (MG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity & Safety Study of a Vaccine Against Meningitis in Infants (2,4,6 Months) After a Hepatitis B Birth Dose.
Status: COMPLETED
Conditions: Diphtheria|Hepatitis B|Haemophilus Influenzae Type b|Whole Cell Pertussis|Tetanus
Interventions: BIOLOGICAL: DTPw-HBV/Hib-MenAC conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Tramadol on Opioid-induced Bowel Dysfunction
Status: COMPLETED
Conditions: Opioid-Induced Bowel Dysfunction|Constipation
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)
Status: WITHDRAWN
Conditions: Coronary Artery Bypass Surgery|Coronary Heart Disease|Coronary Artery Bypass Grafting|Cardiopulmonary Bypass|Ischemic Heart Disease|Heart Failure, Congestive
Interventions: DRUG: Nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Nebulised 3% Hypertonic Saline in Infants With Acute Bronchiolitis
Status: COMPLETED
Conditions: Acute Bronchiolitis
Interventions: DRUG: 3% Sodium Chloride|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Hip Replacement With the Answer® Hip Stem and Ranawat/Burnstein® Shell Using Simplex® or Palacos® Bone Cement
Status: TERMINATED
Conditions: Osteoarthritis, Hip|Traumatic Arthritis of Hip
Interventions: DEVICE: Answer® hip stem|DEVICE: Answer® hip stem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Ocrelizumab (OCR) Treatment Effects on Functional Impairment of MS Patients Enrolled in the Phase III Orchestra Programme Using Multimodal Evoked Potentials (EP) and Highresolution Electroencephalography (EEG)
Status: COMPLETED
Conditions: Multiple Sclerosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Proof of Concept (POC) in Patients With Ischaemic Stroke
Status: TERMINATED
Conditions: Cerebrovascular Accident
Interventions: DRUG: GSK249320 100/mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases
Status: COMPLETED
Conditions: Neoplasm Metastasis|Brain Neoplasm
Interventions: PROCEDURE: Surgery + WBRT|RADIATION: Radiosurgery + WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sargramostim After Bone Marrow Transplantation in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse|Abnormal Uterine Bleeding|Mesh Augmentation|Laparoscopic Surgery|Robotic Surgical Suturing|Laparoscopic Hysterectomy|Minimally Invasive Surgery
Interventions: DEVICE: Articulating laparoscopic instrument|DEVICE: Conventional laparoscopic instrument|DEVICE: Robotic surgical instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Daratumumab|BEHAVIORAL: Questionnaires|OTHER: Dietary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XKH001 Injection in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: XKH001 Injection|DRUG: XKH001 Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Novel Approach in Reducing Dental Pain and Anxiety of Pediatric Patient During Local Anesthesia.
Status: COMPLETED
Conditions: Anxiety|Pain
Interventions: DRUG: Lidocaine Hydrochloride|DEVICE: Virtual reality device (Harga Miniso Vr Glass 3d terbaru)|DIETARY_SUPPLEMENT: Xylitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Guided Biofilm Therapy (GBT) for Treatment of Deep Periodontal Pockets.
Status: NOT_YET_RECRUITING
Conditions: Periodontitis
Interventions: PROCEDURE: guided biofilm therapy|PROCEDURE: root surface debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immunochemotherapy +/- Hypofractionated Radiation for Complete Response in Solid Tumors
Status: WITHDRAWN
Conditions: Metastatic Non-Small Cell Lung Cancer|Metastatic Colon Cancer|Metastatic Triple Negative Breast Cancer
Interventions: DRUG: CTLA-4 Antibody|RADIATION: Hypofractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Lifestyle Change in Obese Pregnant Mothers Through Wearable Internet-of-Things (SLIM)
Status: COMPLETED
Conditions: Pregnancy-Related Condition, Unspecified|Overweight or Obesity
Interventions: BEHAVIORAL: SLIM intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ultrarapid Insulin Administered by a Bihormonal Closed Loop System in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin Lispro Cartridge [Lyumjev]|DRUG: Insulin Lispro Cartridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperational Prostate Loge Biopsies (iPROLOGX) After Radical Prostatovesiculectomy
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: PROCEDURE: biopsies of the prostatic fossa in Magdeburg|PROCEDURE: RPVE|PROCEDURE: ETRARP|PROCEDURE: CE|PROCEDURE: biopsies of the prostatic fossa in gronau
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients
Status: RECRUITING
Conditions: Substance Use Disorders|Substance Use|Substance Dependence
Interventions: BEHAVIORAL: Enhanced Usual Care (EUC)|BEHAVIORAL: TeleTx intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Diode Laser and Topical Steroid Therapy in the Treatment of Erosive Oral Lichen Planus
Status: COMPLETED
Conditions: Erosive Oral Lichen Planus
Interventions: DEVICE: 980nm Diode Laser|DRUG: 0.1% topical triamcinolone Acetonide preparation "Kenacourt-A Orabase"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Local Anesthesia Type on Cancer Detection Rate in Transrectal Ultrasound Guided Prostate Biopsy
Status: COMPLETED
Conditions: Adenocarcinoma of Prostate
Interventions: DRUG: intrarectal lidocaine gel|DRUG: periprostatic nerve blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vorolanib Combined With Cadonilimab in the Treatment of Untreated Advanced RCC Patients
Status: NOT_YET_RECRUITING
Conditions: Kidney Cancer|RCC|Renal Cell Carcinoma
Interventions: DRUG: Vorolanib|DRUG: cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction and Tapering Therapy With Tofacitinib and Glucocorticoid in Patients With Polymyalgia Rheumatica
Status: RECRUITING
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Prednisone+Tofacitinib|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Deficiency Anemia Can be an Indication for Treatment of Subclinical Hypothyroidism
Status: COMPLETED
Conditions: Iron Deficiency Anemia|Subclinical Hypothyroidism
Interventions: DRUG: Ferrous sulfate tablets 325 mg, po, TID|DRUG: Ferrous sulfate plus levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Transpapillary Interventions.
Status: UNKNOWN
Conditions: Endoscopic Surgery
Interventions: PROCEDURE: Endoscopic transpapillary antegrade sphincterotomy developed by Dr. Dovbenko.|DEVICE: The antegrade sphincterotome developed by Dr. Dovbenko.|PROCEDURE: Endoscopic sphincterotomy.|DEVICE: The standard sphincterotome.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety of SL77.0499-10 (Alfuzosin) in Patients With BPH
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: afuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
Status: COMPLETED
Conditions: Cardiac Failure|Myocardial Failure|Congestive Heart Failure|Heart Decompensation
Interventions: DRUG: BMS-986231|DRUG: Furosemide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Colchicine and Clarithromycin
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: colchicine|DRUG: clarithromycin|DRUG: colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stem Cell Gene Therapy for Cystinosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lysosomal Storage Diseases|Cystinosis
Interventions: GENETIC: CTNS-RD-04 or CTNS-RD-04-LB (where the suffix "-LB" stands for LentiBOOST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment of Bartholin´s Cyst or Abscess With Silver Nitrate
Status: UNKNOWN
Conditions: Bartholin´s Cyst
Interventions: PROCEDURE: silver nitrate application to the Bartholin´s cyst|PROCEDURE: silver nitrat stick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT