pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Buccal Pedicle Flap, Connective Tissue Graft and Acellular Dermal Matrix for Volumetric Augmentation of Peri-implant Mucosa
Status: COMPLETED
Conditions: Soft Tissue Augmentation Around Dental Implants
Interventions: PROCEDURE: buccal pedicle flap|PROCEDURE: connective tissue graft|PROCEDURE: acellular dermal matrix|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety in Chinese Patients With Infantile-Onset Pompe Disease With One Year Alglucosidase Alfa Treatment
Status: COMPLETED
Conditions: Glycogen Storage Disease Type II
Interventions: DRUG: ALGLUCOSIDASE ALFA (MYOZYME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Full-thickness REsection of Residual Colorectal Lesions - The FiRE Study
Status: UNKNOWN
Conditions: Adenoma
Interventions: DEVICE: over- the- scope full- thickness resection device (FTRD)|DEVICE: EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
Status: RECRUITING
Conditions: Sleep Apnea|Sleep Apnea, Obstructive
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback Intervention for Preclinical Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Subjective Cognitive Decline|Neurofeedback|Electroencephalogram
Interventions: BEHAVIORAL: Electroencephalogram-based neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Loteprednol Etabonate Versus Vehicle for the Treatment of Inflammation and Pain Following Cataract Surgery
Status: COMPLETED
Conditions: Inflammation|Pain
Interventions: DRUG: Vehicle of Loteprednol Etabonate|DRUG: Loteprednol Etabonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yang Yin Fu Zheng Jie Du Therapy in HBV Related Hepatocellular Carcinoma Induced Anemia (YYFZJDTIHBVRHCIA)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Yang Yin Fu Zheng Jie Du therapy|OTHER: Routine medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Esomeprazole Premedication on Intraoperative Bleeding During Gastric ESD
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Esomeprazole|DRUG: No PPI treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Selinexor Treatment of Advanced Relapsed/Refractory Squamous Cell Carcinomas
Status: TERMINATED
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Selinexor (KPT-330)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Dual Energy/Subtraction CT With MRI for the Identification of Predictors of Malignancy in Cystic Pancreatic Lesions
Status: COMPLETED
Conditions: Pancreatic Cyst
Interventions: DIAGNOSTIC_TEST: Dual energy CT scan with subtraction imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Video Consultations in Type 1 Diabetes Patients Treated With Insulin Pumps in the Outpatient Clinic
Status: RECRUITING
Conditions: Telemedicine|Insulin Dependent Diabetes Mellitus 1
Interventions: OTHER: Intervention group video consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE With Drug Eluting Beads Loaded With Doxorubicin in Liver Metastases From Melanoma Patients
Status: UNKNOWN
Conditions: Stage IV Melanoma Patients With Unresectable Liver Metastases
Interventions: DEVICE: TACE using Drug Eluting Beads loaded with Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Apalutamide (ARN509) and Radical Prostatectomy in Treatment of Intermediate to High Risk Prostate Cancer
Status: COMPLETED
Conditions: Cancer of the Prostate
Interventions: DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of The Efficacy Of Neurolysis In Functional Recovery From Chronic Nonspecific Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DEVICE: Neurotome OFF|PROCEDURE: neurolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Implementation and Effectiveness of Intermittent Preventive Treatment for Malaria Using Dihydroartemisinin-piperaquine on Reducing Malaria Burden in School Aged Children in Tanzania
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Dihydroartemisinin-Piperaquine (DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Operability and Implementation of a Patient Motion Monitoring System Using Wireless Body Worn Sensors
Status: WITHDRAWN
Conditions: Accidental Falls|Gait, Unsteady
Interventions: DEVICE: Smart Slipper|DEVICE: Belt-Clip Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Lehfilcon A multifocal contact lenses|DEVICE: Lotrafilcon B multifocal contact lenses|DEVICE: CLEAR CARE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dacomitinib (PF-00299804) in Advanced/Metastatic Squamous Cell Carcinoma of the Penis
Status: COMPLETED
Conditions: Penile Neoplasms|Carcinoma, Squamous Cell
Interventions: DRUG: Dacomitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in Monotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Intrinsic Pontine Glioma|Medulloblastoma, Childhood, Recurrent
Interventions: BIOLOGICAL: AloCELYVIR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fish Oil Supplementation in Late-life Depression
Status: COMPLETED
Conditions: Late-Life Depression
Interventions: DIETARY_SUPPLEMENT: N-3 polyunsaturated fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Postoperative Quality of Recovery Score in Radical Prostatectomy With Erector Spinae Plane Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Erector Spinae Plane Block|OTHER: Wound Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
Status: RECRUITING
Conditions: Insomnia|Cognitive Dysfunction|Mild Cognitive Impairment|Sleep Initiation and Maintenance Disorders|Sleep Disorders, Intrinsic|Dyssomnias|Sleep Wake Disorders|Nervous System Diseases|Alzheimer Disease
Interventions: BEHAVIORAL: SHUTi OASIS|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
Status: COMPLETED
Conditions: Cataract|Astigmatism
Interventions: DEVICE: AcrySof IQ Toric IOL|DEVICE: AcrySof IQ Aspheric IOL|PROCEDURE: Limbal Relaxing Incision (LRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zhizhu Kuanzhong Capsule for Patients With Functional Dyspepsia-Postprandial Distress Syndrome
Status: UNKNOWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Investigational drug for Functional Dyspepsia-Postprandial Distress Syndrome|DRUG: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Intervention and Social Support in Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: OTHER: Educational intervention for family members/caregivers of people with diabetes mellitus through telephone contact|OTHER: Educational intervention group for people with diabetes through Diabetes Conversation Maps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: BioPearl™ Microspheres Loaded With Doxorubicin for the Treatment of Unresectable Hepatocellular Carcinoma (HCC)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DEVICE: BioPearl™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-electrode Radiofrequency Balloon Catheter Use for the Isolation of the Pulmonary Veins.
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Drugs Used in Hypotensive Anaesthesia on Cochlea
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect|Reflex, Abnormal|Tinnitus, Spontaneous Oto-Acoustic Emission
Interventions: DRUG: Dexmedetomidine|DRUG: esmolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Saxagliptin|DRUG: Saxagliptin|DRUG: Placebo|DRUG: pioglitazone|DRUG: rosiglitazone|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phage 3Determination of Phage/Probiotic Synergistic Effects on Gastrointestinal Health
Status: COMPLETED
Conditions: Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: PreforPro+B. subtilis DE111 probiotics|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: B. subtilis DE111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With Tuberculosis
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary|AIDS
Interventions: DRUG: Rifampicin|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Allergic Rhinitis Therapy by Stem Cells
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Low dose UCMSCs|BIOLOGICAL: Moderate dose UCMSCs|BIOLOGICAL: High dose UCMSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of NC318 in Combination With Chemotherapy for Subjects With Advanced or Metastatic NSCLC
Status: WITHDRAWN
Conditions: Advanced or Metastatic Solid Tumors|Non-Small Cell Lung Cancer
Interventions: DRUG: NC318|DRUG: Pemetrexed/Carboplatin|DRUG: Nab paclitaxel/Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain
Status: RECRUITING
Conditions: Chemotherapy-induced Neuropathic Pain|Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Tetrodotoxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palliative 3-Dimensional Conformal Radiation Therapy in Reducing Radiation Side Effects in Patients With Lung Cancer. ICORG 06-34
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: palliative radiation therapy|RADIATION: whole-brain radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ningetinib (CT053PTSA) Plus Gefitinib in Stage IIIB or IV NSCLC Patients With EGFR Mutation and T790M Negative
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: CT053PTSA|DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Allergic Asthmatics Reactive to Felis Catus (Cat Hair) Allergen Inhalation
Status: TERMINATED
Conditions: Asthma Atopic
Interventions: BIOLOGICAL: Felis Catus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Supervised Therapeutic Exercise in Cancer Patients With and Without Concurrent Treatment.
Status: RECRUITING
Conditions: Breast Cancer|Colon Cancer
Interventions: BEHAVIORAL: Education program on healthy habits|BEHAVIORAL: Habitual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Novel Blueberry Supplement on Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye
Interventions: DIETARY_SUPPLEMENT: Blueberry gummy|DIETARY_SUPPLEMENT: Placebo gummy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Vitamin D in the Treatment of Non-remitted Depression
Status: TERMINATED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Active|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Topical CRx-191 in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CRx-191|DRUG: mometasone furoate|DRUG: nortriptyline HCl|DRUG: Karison® Creme|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Antifibrotic Activity of Fuzheng Huayu in Chronic Hepatitis C Patients With Hepatic Fibrosis
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: Fuzheng Huayu|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tobramycin Inhalation Powder (TIP) in Cystic Fibrosis Patients Infected With Burkholderia Cepacia Complex
Status: COMPLETED
Conditions: Cystic Fibrosis|Burkholderia Cepacia Infection
Interventions: DRUG: TOBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-center Randomized Controlled Study on the Effect of Pharmacogenomics Trial on Clinical Efficacy in Patients With Depression
Status: COMPLETED
Conditions: Depressive Disorder|Pharmacogenomic Drug Interaction
Interventions: DIAGNOSTIC_TEST: pharmacogenomic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Pneumatic Compression Device for Vein Dilation in Kidney Disease Patients to Enable AVF Creation (FACT)
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: DEVICE: Fist Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Treatment Extension Study of Mucopolysaccharidosis Type IIIB
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucopolysaccharidosis Type IIIB|MPS III B
Interventions: DRUG: AX 250
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of a Single Dose of ASP8062 on the Multiple Dose Safety, Tolerability and Pharmacokinetics of Buprenorphine/Naloxone in Participants With Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Use Disorder
Interventions: DRUG: ASP8062|DRUG: Placebo ASP8062|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant
Status: COMPLETED
Conditions: Complications; Contraceptive|Female Lactation
Interventions: DRUG: Etonogestrel contraceptive implant|DRUG: Etonogestrel contraceptive implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability and Pharmacokinetic Study of Recombinant Human Interferon Alfa 2B in Chronic Hepatitis C Patients (HM10660A)
Status: UNKNOWN
Conditions: Chronic Hepatitis C Virus Genotype I
Interventions: DRUG: HM10660A|DRUG: Pegasys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Patient Education Given by Teach-Back Method on Managing Chemotherapy Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Teach-Back Communication
Interventions: OTHER: Trained by teaching back method|OTHER: Management training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Capecitabine, Gemcitabine, and Bevacizumab in Combination for Patients With Sarcomatoid Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: Capecitabine|DRUG: Gemcitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Locally Advanced Breast Cancer Using Vorinostat Plus Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Vorinostat|DRUG: Paclitaxel|DRUG: Trastuzumab|DRUG: Doxorubicin|DRUG: Cyclophosphamide|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Assisted Cognitive Behavior Therapy for Obsessive Compulsive Disorder: A Comprehensive Stepped-Care Approach
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Computer-Assisted Cognitive Behavior Therapy (BT STEPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ibuprofen in Term Newborns With Patent Ductus Arteriosus (PDA)
Status: COMPLETED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Oral Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ECG AI-Guided Screening for Low Ejection Fraction
Status: COMPLETED
Conditions: Asymptomatic Left Ventricular Systolic Dysfunction (Disorder)|Heart Failure
Interventions: OTHER: AI-enabled ECG-based Screening Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: First Episode Schizophrenia and Cannabis-Related Disorder Study
Status: COMPLETED
Conditions: Cannabis-Related Disorder|Substance-Related Disorders|Schizophrenia|Psychotic Disorders
Interventions: DRUG: clozapine|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predicting Treatment Response to Exposure Therapy Using Carbon Dioxide
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|Social Anxiety Disorder|Panic Disorder|Agoraphobia
Interventions: BEHAVIORAL: Exposure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Speed of Premolar Extraction Space Closure: Every Visit Replacement of Working Archwire
Status: COMPLETED
Conditions: Orthodontic Appliance
Interventions: DEVICE: Space closure without changing working archwire monthly|DEVICE: Space closure withchanging working archwire monthly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of the Orthoglide for Improved Patient Outcome Following Total Knee Replacement
Status: COMPLETED
Conditions: Knee Osteoarthritis|Physiotherapy|Intervention|Rehabilitation|Exercise
Interventions: DEVICE: Orthoglide|OTHER: Physiotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Assessment of NIlotinib in CML Patients With Suboptimal Response on Imatinib Therapy
Status: TERMINATED
Conditions: Myeloid Leukemia, Chronic
Interventions: DRUG: Nilotinib 300 mg.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PB125, Osteoarthritis, Pain, Mobility, and Energetics
Status: TERMINATED
Conditions: Osteoarthritis, Knee|Muscle Weakness|Pain, Joint
Interventions: DIETARY_SUPPLEMENT: PB125|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relevance of Flavanols for Cardiovascular Function in End-Stage Renal Disease
Status: WITHDRAWN
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: low and high dose flavanoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status
Status: TERMINATED
Conditions: Systemic Inflammatory Response Syndrome|Distributive Shock|Hypotension and Shock|Decompensated Congestive Heart Failure|Atrial Fibrillation|High Risk Non-cardiac Surgery
Interventions: PROCEDURE: Peripheral Intravenous Analysis (PIVA)|PROCEDURE: Standard of care invasive vascular monitoring|PROCEDURE: Standard noninvasive vascular monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A National Multicentre Study to Assess the Efficacy of the Fixed Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled by Monotherapy
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: valsartan/amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Herbal Dentifrice in Treatment of Chronic Periodontitis
Status: RECRUITING
Conditions: Chronic Periodontitis
Interventions: DRUG: Dentifrice Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study on the Transfer of the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma
Status: WITHDRAWN
Conditions: Esophageal Neoplasms
Interventions: GENETIC: CD40 Gene Transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Serum Levels of Adenosine Deaminase and Immunoglobulin E in Patients With Chronic Spontaneous Urticaria
Status: NOT_YET_RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DIAGNOSTIC_TEST: Adenosine deaminase serum level|DIAGNOSTIC_TEST: IgE antibodies serum level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Rosuvastatin Therapy on HDL2 Level
Status: UNKNOWN
Conditions: Hyperlipemia|Coronary Heart Disease
Interventions: DRUG: Rosuvastatin 10mg/d group|DRUG: Rosuvastatin 20mg/d group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of Olmesartan/Amlodipine/Rosuvastatin Combination Treatment in Patients With Concomitant Hypertension and Hyperlipidemia
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemias
Interventions: DRUG: Amlodipine/Olmesartan 10/40mg (Combination drug), Rosuvastatin 20mg|DRUG: Olmesartan 40 mg, Rosuvastatin 20mg|DRUG: Amlodipine/Olmesartan 10/40mg (Combination drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: RADIATION: BNCT(boron neutron capture therapy)|RADIATION: XRT(X-ray radiation treatment)|DRUG: TMZ(temozolomide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Lotemax Versus FML in Subjects Undergoing PRK for the Correction of Mild to Moderate Myopia, 3- Month Follow-up Study
Status: UNKNOWN
Conditions: Must be PRK Candidate
Interventions: DRUG: Fluorometholone(FML)|DRUG: Loteprednol (Lotemax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S9806: Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: docetaxel|DRUG: gemcitabine|DRUG: paclitaxel|DRUG: vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Paclitaxel, Gemcitabine and Cisplatin in Patients With Relapsing Germ Cell Cancer
Status: TERMINATED
Conditions: Testicular Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carboplatin|DRUG: tamoxifen citrate|DRUG: temozolomide|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Awake & Move - Part II
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: BEHAVIORAL: REMSA|BEHAVIORAL: NREMSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Pharmacokinetics of Orally Administered Gallium Maltolate in Various Refractory Malignancies
Status: TERMINATED
Conditions: Prostatic Neoplasms|Multiple Myeloma|Bladder Neoplasms|Lymphoma
Interventions: DRUG: Gallium maltolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Analgesic Compound Efficacy (PACE) Study
Status: COMPLETED
Conditions: Arthritis|Tendonitis|Gout|Radiculopathy|Muscle Spasms|Synovitis|Migraine|Headache
Interventions: DRUG: baclofen 2%|DRUG: Bupivacaine hydrochloride 1%|DRUG: Cyclobenzaprine hydrochloride 2%|DRUG: Diclofenac Sodium 3%|DRUG: Flurbiprofen 10%|DRUG: Gabapentin 6%|DRUG: Ketamine 10%|DRUG: Lidocaine 2%|DRUG: Prilocaine 2.5%|DRUG: Meloxicam 0.09%|DRUG: Sumatriptan 5%|DRUG: Tizanidine 0.1%|DRUG: Topiramate 2.5%|DRUG: Capsaicin, USP 0.0375%|DRUG: Menthol, NF 5.00 %
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects
Status: NOT_YET_RECRUITING
Conditions: Bipolar Disorder|Major Depressive Disorder
Interventions: DIAGNOSTIC_TEST: EDIT-B test|DIAGNOSTIC_TEST: EDIT-B test (without giving result)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Digital Pre-therapy Patient Education Program (StartHjelp) in Outpatient Mental Health Care
Status: NOT_YET_RECRUITING
Conditions: Mental Health Issue|Mental Disorder|Patient Education
Interventions: BEHAVIORAL: Digital pre-therapy patient education program (StartHjelp)|BEHAVIORAL: Comparator intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Adults With Generalized Myasthenia Gravis
Status: COMPLETED
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: M281|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
Status: WITHDRAWN
Conditions: Autistic Disorder
Interventions: DRUG: Medical Grade Cannabis oil|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0004: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Limited-stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|DRUG: tirapazamine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balance, Plantar Pressure Distribution and Gait in Pes Planus
Status: COMPLETED
Conditions: Pes Planus
Interventions: DIAGNOSTIC_TEST: Navicular Drop Test|DIAGNOSTIC_TEST: Foot Posture Index|DIAGNOSTIC_TEST: Balance|DIAGNOSTIC_TEST: Plantar Pressure Analysis|DIAGNOSTIC_TEST: Gait Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Music Therapy on Psychological States Among Cancer Patients Undergoing MRI Scans and A Relevant Mediator
Status: RECRUITING
Conditions: Psycho-Oncology
Interventions: OTHER: Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Fermented Cinnamon Vine Powder on Decrement of Body Fat
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Fermented Cinnamon Vine Powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Effects of Oligomeric Procyanidins (OPCs) in Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DIETARY_SUPPLEMENT: oligomeric proanthocyanidins (MASQUELIER'S Original OPCs)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Psychosocial and Physiological Mechanisms in the Effect of Hormonal Contraception on the Female Sexual Desire
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nuvaring|DRUG: low-dose combination pill|DRUG: minipill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Sinus Floor Augmentation in Conjunction With Immediate Implant Loading - Study on 3i Dental Implants
Status: COMPLETED
Conditions: Mouth, Edentulous
Interventions: PROCEDURE: Bilateral sinus augmentation with immediately loaded dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple or Dual Antithrombotic Therapy After PCI (TRIDUAL-PCI) Coronary Intervention in Patients With Non-valvular Atrial Fibrillation. Real-world Italian Multicenter Registry (TRIDUAL-PCI)
Status: UNKNOWN
Conditions: Atrial Fibrillation|Myocardial Infarction|Anticoagulant-induced Bleeding|Coronary Disease
Interventions: DRUG: Antithrombotic Agent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality Control: A Prospective Analysis of EVD Effectiveness
Status: TERMINATED
Conditions: Catheter Related Infections
Interventions: DEVICE: The Integra External Drainage Catheter.|DEVICE: The Ventriclear EVD Antibiotic Catheter|DEVICE: The Codman Bactiseal EVD Catheter Set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: VNP40101M in Treating Patients With Acute Myelogenous Leukemia or High-Risk Myelodysplasia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: hydroxyurea|DRUG: laromustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Wheelchair Propulsion Training Program
Status: COMPLETED
Conditions: Spinal Cord Injuries|Multiple Sclerosis|Amputation|Spina Bifida
Interventions: BEHAVIORAL: In-person wheelchair propulsion training program|BEHAVIORAL: 30-minute education session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of Ascending Doses of ARN 509 in Combination With Abiraterone Acetate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ARN-509|DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Escalating Doses of DCDS0780A in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: DCDS0780A|DRUG: Rituximab|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab After Stereotactic Ablation Brachytherapy for Refractory Oligometastatic Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Oligometastasis|Lung Neoplasms
Interventions: DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA PET in Diagnosing Metastasis in Patients With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Carcinoma
Interventions: DRUG: Gallium Ga 68-labeled PSMA-11|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Positron Emission Tomography (PET)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Deep Neuromuscular Blockade During Robot-assisted Transaxillary Thyroidectomy on Postoperative Pain and Sensory Change
Status: COMPLETED
Conditions: Thyroid Neoplasms
Interventions: DRUG: Deep Group|DRUG: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Contrast Enhanced MRI of the CNS - Patients With Known Cerebral Neoplastic Lesions.
Status: COMPLETED
Conditions: Neoplastic CNS Lesions
Interventions: DRUG: Gadovist® (Gadobutrol, BAY86-4875)|DRUG: Dotarem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hyoscine ButylBromide for Intrapartum Analgesia
Status: UNKNOWN
Conditions: Analgesia, Obstetrical
Interventions: DRUG: Hyoscine|DRUG: Pethidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Fiber Fortified Foods to the Diets of Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Control Food|OTHER: Fiber Fortified Food
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lidocaine Infusion on Optic Nerve Sheath Diameter in Laparoscopic Hysterectomy in Trendelenburg Position
Status: COMPLETED
Conditions: Lidocaine|Optic Nerve Sheath Diameter|Laparoscopic Hysterectomy|Trendelenburg
Interventions: DRUG: Lidocaine|DRUG: sodium chloride 0.9% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Disodium in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
Status: TERMINATED
Conditions: Premenstrual Syndrome|Mastodynia
Interventions: DRUG: 20mg VAC BNO 1095 FCT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrite in Hypertrophic Cardiomyopathy (HCM) Study
Status: UNKNOWN
Conditions: Cardiomyopathy, Hypertrophic
Interventions: DRUG: Sodium Nitrate|DRUG: Placebo|DIAGNOSTIC_TEST: Phosphorous Magnetic Resonance Spectroscopy|DIAGNOSTIC_TEST: Exercise Stress Transthoracic Echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess Adverse Events and Effectiveness of HAC 20L Injections in Adult Participants for the Treatment of Nasolabial Folds
Status: ACTIVE_NOT_RECRUITING
Conditions: Nasolabial Folds
Interventions: OTHER: No-Treatment Control|DEVICE: HAC 20L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Males, Antioxidants, and Infertility Trial
Status: COMPLETED
Conditions: Male Infertility
Interventions: DRUG: Antioxidant Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Total Hip Arthroplasty: Fluoroscopy vs Freehand
Status: RECRUITING
Conditions: Intraoperative Fluoroscopy
Interventions: DEVICE: Intraoperative fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crisis Line Facilitation
Status: COMPLETED
Conditions: Suicide|Suicide, Attempted|Hospitals, Psychiatric
Interventions: BEHAVIORAL: Crisis Line Facilitation (CLF)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BARD® The VENOVO™ Venous Stent Study for Treatment of Iliofemoral Occlusive Disease
Status: COMPLETED
Conditions: May-Thurner Syndrome|Peripheral Vascular Disease|Venous Disease|Iliofemoral Occlusive Disease
Interventions: DEVICE: VENOVO™ Venous Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Knee Needle Arthroscopy in Predicting Unicompartmental Knee Osteoarthritis
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: NanoScope™ Operative Arthroscopy (Arthrex, Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Osmoprotective Containing Lubricants in Dysfunctional Tear Syndrome and Post Refractive Surgery Patients
Status: COMPLETED
Conditions: Dry Eye|Ametropia
Interventions: OTHER: Optive ®|OTHER: Fresh Tears ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pacritinib Versus Best Available Therapy to Treat Myelofibrosis
Status: TERMINATED
Conditions: Primary Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis
Interventions: DRUG: Pacritinib|DRUG: Best Available Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calf Circumference Versus X-ray Absorptiometry in the Diagnosis of Sarcopenia in Elderly Hospitalized Patients
Status: RECRUITING
Conditions: Sarcopenia
Interventions: RADIATION: Dual-energy X-ray absorptiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)
Status: TERMINATED
Conditions: Bipolar Disorder|Depression
Interventions: DRUG: PF-04455242
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of BB-12 Supplemented Strawberry Yogurt For Healthy Children
Status: COMPLETED
Conditions: Children
Interventions: DRUG: BB-12 supplemented strawberry yogurt|OTHER: Strawberry flavored yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Rapid Structural and Functional Improvements in Following 0.19 mg Fluocinolone Acetonide (FAc) Implant in Diabetic Macular Edema Patients With Poor Visual Acuity: 12-month Audit Results From United Arab Emirates
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: 0.19 mg fluocinolone acetonide (FAc) implant|DEVICE: 0.19 mg fluocinolone acetonide (FAc) implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines
Interventions: DRUG: RT001|DRUG: RT001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TB (Tuberculosis) Preventive Therapy for HIV Patients With Access to HAART (Highly Active Antiretroviral Therapy)
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: INH preventive therapy|DRUG: TST (tuberculin skin test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Vaccine Trial for Low Grade Gliomas
Status: RECRUITING
Conditions: Low Grade Glioma
Interventions: BIOLOGICAL: Experimental: HLA-A2 Restricted Glioma Antigen-Peptides with Poly-ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT