pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation
Status: COMPLETED
Conditions: Cataract|Dry Eye
Interventions: DRUG: Topical Cyclosporine, Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Outcome of Cognitive Behavioral Therapy for Patients With Severe Health Anxiety Treated in Group Only. A RCT.
Status: COMPLETED
Conditions: Severe Health Anxiety|Hypochondriasis|Illness Anxiety Disorder|Somatic Symptom Disorder|Personality Disorders
Interventions: BEHAVIORAL: Group-Cognitive Behavioral Therapy|OTHER: Wait-List with treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Prospective Study of the Arthroscopic Meniscus Repair Methods
Status: RECRUITING
Conditions: Meniscus Tear Caused by a Traumatic Event
Interventions: PROCEDURE: Arthroscopic meniscus repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of CT-guided Sarcopenia for Surgical Outcomes in Esophagetomy and Total Gastrectomy Due to Neoplasia
Status: COMPLETED
Conditions: Sarcopenia|Malnutrition|Gastrostomy|Esophagostomy Complication|Computed Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Videolaryngoscope vs Classic Laryngoscope in Teaching Neonatal Endotracheal Intubation: a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: DEVICE: Miller laryngoscope|DEVICE: Storz videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Holbæk Obesity Treatment (HOT) Versus Conventional Obesity Treatment (COT) in Children With Overweight or Obesity.
Status: RECRUITING
Conditions: Childhood Overweight and Obesity
Interventions: BEHAVIORAL: Holbæk Obesity Treatment|BEHAVIORAL: Conventional Obesity Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GDT by Cardiac Index Trending Via a Radial Arterial Line in General Surgery
Status: COMPLETED
Conditions: Reduction of Length of Hospitality Stay, Reduction of Perioperative Complications
Interventions: DEVICE: measurement of cardiac output and pulse pressure variation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Clinical Trials to Evaluate Pharmacokinetics of Unboosted and Boosted Atazanavir Used Alone or Co-administered With Tenofovir DF in Healthy Korean and Caucasian Male Volunteers
Status: UNKNOWN
Conditions: Atazanavir
Interventions: DRUG: atazanavir|DRUG: Atazanavir(ATZ) and Tenofovir(TDF)|DRUG: Atazanavir(ATZ) + Ritonavir|DRUG: atazanavir(ATZ) + tenofovir(TDF) + ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identification of Genetic Polymorphisms Related to Propofol Requirement and Recovery Through Genome-wide Association Study (GWAS) in Total Intravenous Anesthesia for Clipping of Unruptured Cerebral Aneurysm in Korean Population
Status: UNKNOWN
Conditions: Unruptured Cerebral Aneurysm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Engaging Informal Health Care Providers on Case Detection and Treatment Initiation Rates for TB and HIV in Rural Malawi (Triage Plus)
Status: COMPLETED
Conditions: Tuberculosis|HIV
Interventions: BEHAVIORAL: Early intervention|BEHAVIORAL: Delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Knee Arthroplasty Pain Coping Skills Training (KASTPain): A Randomized Trial
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Pain Coping Skills Training|BEHAVIORAL: Arthritis Education|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Excposure of High Altitude on ECG and Non-invasive Blood Pressure.
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Low altitude: 470m above sea level|OTHER: Säntis; 2500m above sea Level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Platelet Enriched Gel Versus Metalloproteinase Inhibitor in the Healing of Chronic Lower Leg Ulcers
Status: COMPLETED
Conditions: Chronic Lower Leg Ulcer
Interventions: OTHER: Autologous Platelet Enriched Gel|OTHER: Metalloproteinase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Implementation of the Assessment of Burden of Chronic Conditions (ABCC)-Tool
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Diabetes Mellitus, Type 2|Heart Failure
Interventions: DEVICE: Assessment of Burden of Chronic Conditions (ABCC)-tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial, Conventional Treatment-controlled, Studying the Efficacy of Plasma Rich in Growth Factor (PRGF®) in Alveolar Ridge Preservation After Simple Exodontia in the Anterior Region of Maxilla.
Status: UNKNOWN
Conditions: Dental Implantation
Interventions: PROCEDURE: Exodontia|DRUG: Alveolar ridge preservation with a PRP (PRGF-Endoret)|DEVICE: Preparation of PRGF using Endoret technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|DRUG: Idarubicin|DRUG: Idelalisib|DEVICE: In Vitro Kinase Inhibitor Assay|DRUG: Leucovorin Calcium|DRUG: Methotrexate|DRUG: Methylprednisolone Sodium Succinate|DRUG: Ponatinib Hydrochloride|BIOLOGICAL: Rituximab|DRUG: Ruxolitinib Phosphate|DRUG: Sorafenib Tosylate|DRUG: Sunitinib Malate|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate and Delayed Dentin Sealing Effect on Partial Crowns
Status: COMPLETED
Conditions: Adhesion|Tooth|Crown|Luting|Immediate Dentin Sealing
Interventions: OTHER: Immediate Dentin Sealing or Delayed Dentin Sealing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Desensitization in Kidney Transplantation
Status: COMPLETED
Conditions: HLA Sensitization
Interventions: DRUG: plasmapheresis|DRUG: Bortezomib|DRUG: Rituximab|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Glycemic Effect of Added Sugar on Bake Beans
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity|PreDiabetes
Interventions: OTHER: Glucose Reference 1|OTHER: Glucose Reference 2|OTHER: Glucose reference 3|OTHER: Sucrose|OTHER: Regular Bake beans in tomato sauce|OTHER: Bake beans in tomato sauce, reduced sugar|OTHER: Bake beans in tomato sauce, low GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Speech Intelligibility in Quiet and Noise for New vs. Legacy Hearing Aids
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Hearing Loss
Interventions: DEVICE: New Receiver-in-Canal Device|DEVICE: Legacy Receiver-in-Canal Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use Test: Dermowas Body Lotion pH 4 vs. pH 5.8
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: WO 5000|OTHER: WO 5001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating the Safety of LEO 90105 and Its Vehicle, After Multiple Administration on Intact Skin of Healthy Japanese Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LEO 90105
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma in Situ
Interventions: DRUG: STP705|OTHER: Placebo Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preservation of Beta-cell Function in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Insulin|DRUG: Metfomin|DRUG: Pioglitazone|DRUG: glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Study to Investigate the Efficacy of a New Medical Device (Modified Diprobase Formulation)
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DEVICE: BAY987534
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride (HCl) in Indolent Non-Hodgkin's Lymphoma That Has Progressed During or Following Treatment With a Rituximab Regimen or Previously Untreated Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Indolent Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine at a dose of 100 mg/m2|DRUG: Bendamustine at a dose of 120 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Detection Algorithms for Insulin Pump Malfunctions in Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type I
Interventions: OTHER: Simulation of an insulin pump failure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Study of Colorectal Cancer and Prostate Cancer Screening Decision Making
Status: COMPLETED
Conditions: Colorectal Cancer|Colon Cancer|Prostate Cancer
Interventions: OTHER: Rating and Ranking Task|OTHER: Discrete Choice Task|OTHER: Balance Sheet Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Nitazoxanide|DRUG: Clarithromycin|DRUG: Metronidazole|DRUG: Proton pump inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: dasatinib|DRUG: vorinostat|GENETIC: cytogenetic analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma
Status: COMPLETED
Conditions: Scleroderma
Interventions: DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546|DRUG: MEDI-546
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Characteristics of Patients With SARS-CoV-2
Status: COMPLETED
Conditions: Coronavirus|SARS-CoV-2|COVID-19|Acute Respiratory Distress Syndrome|Shock|Acute Circulatory Failure|Left Ventricular Dysfunction|Fluid Overload
Interventions: DEVICE: Transpulmonary thermodilution|DEVICE: Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Convalescent Plasma Compared to the Best Available Therapy for the Treatment of SARS-CoV-2 Pneumonia
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: BIOLOGICAL: Plasma|OTHER: Best Available Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders
Status: WITHDRAWN
Conditions: Premenstrual Syndrome|Premenstrual Dysphoric Disorder|Premenstrual Tension|Menstrual Related Mood Disorder
Interventions: DRUG: EnBrace HR Softgel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Idiazole 20mg DR Tabs and PARIET® 20 mg DR Tabs After a Single Oral Dose Administration Under Fasting Conditions in Healthy Adults
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DRUG: Idiazole 20mg DR tabs|DRUG: PARIET 20 mg DR tabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study for Patients With Non Small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Adsorption in Post-cardiac Arrest Syndrome in Patients Requiring Extracorporeal Cardiopulmonary Resuscitation
Status: COMPLETED
Conditions: Cardiac Arrest|Extracorporeal Circulation|Extracorporeal Membrane Oxygenation|Cytokine Storm|Cytokine Release Syndrome|Post-Cardiac Arrest Syndrome
Interventions: DEVICE: Cytosorb removal column in eCPR|DEVICE: standard eCPR (va-ECMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial to Evaluate the Safety, Pharmacokinetics and Antiviral Activity of 141W94 After Multiple Dosing in Patients With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Children With Refractory or Relapsed ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Topotecan, dexamethasone, vincristine|DRUG: E. coli Asparaginase, PEG-L-asparaginase|DRUG: erwinia asparaginase|DRUG: fludarabine, methotrexate, mercaptopurine|DRUG: idarubicin, etoposide, cytarbine, teniposide|PROCEDURE: chemotherapy, intrathecal chemotherapy, steroid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AGN 203818 for Pain Associated With Painful Bladder Syndrome/Interstitial Cystitis
Status: TERMINATED
Conditions: Cystitis, Interstitial
Interventions: DRUG: AGN 203818
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Disitamab Vedotin Plus Toripalimab and XELOX in Gastric or Gastroesophageal Junction Adenocarcinoma.
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: oxaliplatin|DRUG: Disitamab Vedotin|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yiqi Wenjing Prescriptions Preventive Efficacy of Oxaliplatin-induced Peripheral Neuropathy Clinical Trial
Status: UNKNOWN
Conditions: Chemotherapy-induced Peripheral Neuropathy|Colorectal Cancer
Interventions: DRUG: Mimetic granules of Yiqi-Wenjing prescriptions|DRUG: Huangqi-Guizhi-Wuwu granules|DRUG: Danggui-Sini granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: To Compare the Blood Level of Marketed Japanese Valsartan Tablet Formulation vs Global Valsartan Tablet Formulation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Fetal Growth Restriction in Monochorionic Twins - an International Investigation
Status: RECRUITING
Conditions: Twin; Pregnancy, Affecting Fetus or Newborn|Fetal Growth Retardation|Twin Monochorionic Diamniotic Placenta|Twin Diseases
Interventions: DIAGNOSTIC_TEST: Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Pressure Pneumoperitoneum and Deep Neuromuscular Block Versus Standard Laparoscopy During Robot Assisted Radical Prostatectomy to Improve the Quality of Recovery and Immune Homeostasis; Study Protocol for a Randomized Controlled Study.
Status: COMPLETED
Conditions: Quality of Life|Postoperative Complications|Acute Pain|Immune System Tolerance
Interventions: OTHER: Low intra-abdominal pressure|OTHER: Deep neuromuscular blockade (NMB)|OTHER: Standard intra-abdominal pressure|OTHER: Moderate neuromuscular blockade (NMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of 3g Versus 2 g MMF in Combination With Tacrolimus on Progression of Renal Allograft Interstitial Fibrosis
Status: COMPLETED
Conditions: Kidney Transplantation|Kidney Failure
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Omega-3 Bioavailability From Vegetable-omega-3 Enriched Products
Status: UNKNOWN
Conditions: Lifestyle
Interventions: DIETARY_SUPPLEMENT: Experimental: Control|DIETARY_SUPPLEMENT: Experimental: Treatment 1 - Semi-Solid food matrix|DIETARY_SUPPLEMENT: Treatment 2 - Solid food matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Intrapartum Oropharyngeal (IP-OP) Suction on Meconium Aspiration Syndrome
Status: COMPLETED
Conditions: Meconium Aspiration Syndrome
Interventions: PROCEDURE: Intrapartum Oropharyngeal Suctioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aspirin Discontinuation After Left Atrial Appendage Occlusion in Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke|Bleeding
Interventions: DRUG: Aspirin Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estimation of Glomerular Filtration Flow in Patients of Resuscitation Under Extra-bodily Assistance
Status: UNKNOWN
Conditions: Extracorporeal Membrane Oxygenation Complication
Interventions: DIAGNOSTIC_TEST: Ultrasound for renal resistivity index measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-reported Outcomes in Vericiguat-treated Patients With HFpEF
Status: COMPLETED
Conditions: Chronic Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Vericiguat (BAY1021189) 2.5 mg, 5 mg or 10 mg IR tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketorolac in Postoperative Infants: Pharmacokinetics and Safety
Status: COMPLETED
Conditions: Postoperative Pain in Infants
Interventions: DRUG: Ketorolac Tromethamine 1 mg/kg|DRUG: Ketorolac Tromethamine 0.5 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Adalimumab on Mucosal Healing in Subjects With Crohn's Disease Involving the Colon
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: placebo|BIOLOGICAL: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress in Hypobaric Hypoxia
Status: COMPLETED
Conditions: Hypobaric Hypoxia|Metabolomics|Oxidative Stress|Acute Mountain Sickness
Interventions: OTHER: Hypoxic exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Glucagon on Uterine Contractility at the Time of Embryo Transfer in in Vitro Fertilization
Status: WITHDRAWN
Conditions: Women With Fertility Disorder
Interventions: DRUG: Glucagon|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Telerehabilitation Intervention Program Using Telebiofeedback Among Computer Operators
Status: UNKNOWN
Conditions: Work Related Musculoskeletal Disorders
Interventions: DEVICE: surface electromyography|DEVICE: surface electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocolloids as Functional Food Ingredients for Gut Health
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Agar H1CC2013|DIETARY_SUPPLEMENT: Agar H1CC2012|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing the Management of Flares in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: FLARE Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of the GORE® Septal Occluder to Treat Ostium Secundum Atrial Septal Defects
Status: COMPLETED
Conditions: Septal Defect, Atrial
Interventions: DEVICE: GORE® CARDIOFORM Septal Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Euglycemic Clamp Study Comparing Two New Insulin Glargine Formulations in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type1 Diabetes
Interventions: DRUG: Insulin glargine new formulation HOE901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Adjunctive to Open-Label Aripiprazole for the Treatment of Bipolar Disorder in Children and Adolescents
Status: TERMINATED
Conditions: Pediatric Bipolar Disorder
Interventions: DRUG: Aripiprazole|DIETARY_SUPPLEMENT: fish oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation on the Treatment of Radiation Induced Dermatitis With FR-101 Chest Dressing
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Radiation Dermatitis
Interventions: DEVICE: FR-101 Chest Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Application of PLDR External Irradiation Combined With Immune Checkpoint Inhibitors in Recurrent Cervical Cancer
Status: RECRUITING
Conditions: Cervical Squamous Cell Carcinoma|Radiotherapy|Immunotherapy
Interventions: RADIATION: PLDR+Cardunizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clobetasol Propionate Versus Fractionated Carbon Dioxide Laser for the Treatment of Lichen Sclerosus
Status: COMPLETED
Conditions: Vulvar Lichen Sclerosus
Interventions: DEVICE: Fractionated Carbon Dioxide Laser|DRUG: Clobetasol Propionate 0.05% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Fresh Platelet Rich Plasma With Concentrated Leukocytes or Fresh Platelet Rich Plasma Without Concentrated Leukocytes in the Treatment of Knee Cartilage Degeneration: a Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Fresh Platelet Rich Plasma with leukocyte|OTHER: Fresh Platelet Rich Plasma without leukocyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Spondylitis, Ankylosing
Interventions: BIOLOGICAL: golimumab|BIOLOGICAL: Golimumab (CNTO 148); placebo|BIOLOGICAL: golimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Nebulized Heparin Versus Placebo for Inhalation Trauma
Status: TERMINATED
Conditions: Inhalation Injury|Burn Injury
Interventions: DRUG: unfractionated heparin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aliskiren on Endothelial Function in Pre-Diabetes and Diabetes
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: Placebo|DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Escalation Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Healthy Adults
Status: RECRUITING
Conditions: Cholera Vaccination Reaction
Interventions: BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine Cohort A|BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine with Aluminum phosphate adjuvant Cohort A|OTHER: Placebo Cohort A|BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine Cohort B|BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine with Aluminum phosphate adjuvant Cohort B|OTHER: Placebo Cohort B|BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine Cohort C|BIOLOGICAL: OSP:rTTHc Cholera Conjugate Vaccine with Aluminum phosphate adjuvant Cohort C|OTHER: Placebo Cohort C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Ketamine and Dexmedetomidine in Opioid-Sparing Analgesia
Status: COMPLETED
Conditions: Ketamine-Induced Mood Disorder
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Posttraumatic Stress Disorder (PTSD) With Diazepam
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Peri-Operative Pregabalin on Post-Operative Pain Following Breast Cancer Surgery With Axillary Node Dissection: A Pilot Study
Status: COMPLETED
Conditions: Breast Cancer Surgery|Post Operative Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate Anecortave Acetate vs. Visudyne for the Treatment of the Wet Form of AMD
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Anecortave Acetate 15 mg sterile suspension|OTHER: Photodynamic Therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Glycomics as Prognostic and Diagnostic Biomarkers of Disease Recurrence in Liver Transplant Recipients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Prognostic Biomarker|Liver Transplantation|Diagnostic Biomarker|Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: HCCRecurrencePrognosticScore|DIAGNOSTIC_TEST: HCCRecurrenceDiagnosticScore
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Androgenetic Alopecia Treatment Using Varin and Cannabidiol Rich Topical Hemp Oil: A Case Series
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DRUG: Hemp Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4905417 in Patients With Non ST-Elevation Myocardial Infarction (Non-STEMI) Undergoing Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Percutaneous Coronary Intervention (PCI)|DRUG: RO4905417|DRUG: RO4905417|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Neoplasms
Interventions: DRUG: Adjuvant chemotherapy (Paclitaxel and Cisplatin)|RADIATION: Adjuvant radiotherapy|OTHER: Control group (Surgery alone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-derived Organoids Drug Screen in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreas Cancer|Pancreas Neoplasm|Pancreas Adenocarcinoma|Pancreatic Cancer|Pancreatic Neoplasms|Pancreatic Adenocarcinoma
Interventions: PROCEDURE: Surgical biopsy of tumoral tissue for organoid generation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of New Anti-HIV Drug Combinations in HIV-Infected Children Who Have Taken Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Nevirapine|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Opioid-free Anaesthesia in Breast Cancer Surgery
Status: RECRUITING
Conditions: Breast Cancer|Anesthesia|Pain, Postoperative|Pain, Chronic|Opioid Free Anaesthesia|Cancer Recurrence
Interventions: OTHER: Opioid Free Anaesthesia (OFA)|OTHER: Conventional General Anaesthesia (CGA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irintoecan|DRUG: HA-Irinotecan solution for Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supporting the National Expansion of HPV-based Cervical Cancer Screening in Tanzania Among Women Living With HIV
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: Vaccination Provision|BIOLOGICAL: Vaccination Provision 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Recombinant Human Interferon a-2b Gel for HPV-16 and/ or HPV-18 Gynecological Infections
Status: UNKNOWN
Conditions: Cervical HPV-16 and / or HPV-18 Infection
Interventions: DRUG: Yallaferon®， the recombinant human interferon α-2b gel|OTHER: gel without active ingredient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Single Dose of Ferrinemia® Injection With a Single Dose of Venofer® Injection in Healthy Male Volunteers
Status: COMPLETED
Conditions: Heathy Volunteers
Interventions: DRUG: Ferrinemia|DRUG: Venofer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Moxifloxacin, Ethambutol, Isoniazid, Pyrazinamide & Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canola Oil, Fibre and DHA Enhanced Clinical Trial
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Butter, sunflower and safflower oil|DIETARY_SUPPLEMENT: High Oleic Canola Oil and DHA (HOCO-DHA)|DIETARY_SUPPLEMENT: Barley beta-glucan|DIETARY_SUPPLEMENT: HOCO-DHA and Barley beta-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-Label, Dose Escalation Study of ANG1005 in Patients With Advanced Solid Tumors and Metastatic Brain Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors With and Without Brain Metastases
Interventions: DRUG: ANG1005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparing Enoxaparin to Fondaparinux to Prevent Venous Thromboembolism (VTE) in Bariatric Surgical Patients
Status: COMPLETED
Conditions: Deep Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: Enoxaparin|DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supporting Parenting at Home: Empowering Rehabilitation Through Engagement (SPHERE)
Status: UNKNOWN
Conditions: Neurodevelopmental Disorders
Interventions: OTHER: Telemedicine Video Feedback Intervention|OTHER: Psychoeducational Booklet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Transcranial Direct Current Stimulation (tDCS) and Cognitive Training in Patients With TBI
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Closed Traumatic Brain Injury|Severe Brain Injury
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chamomile Therapy for Generalized Anxiety
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DIETARY_SUPPLEMENT: Chamomile Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Surgical Skin Preps During Cesarean Deliveries
Status: COMPLETED
Conditions: Surgical Site Infection Following Cesarean Delivery
Interventions: DRUG: Iodine povidone|DRUG: Chlorhexidine|DRUG: Combination iodine and chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms
Status: UNKNOWN
Conditions: Dissecting Aneurysm of Cerebral Artery|Intramural Hematomas|Inflammation Vascular
Interventions: DRUG: Atorvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluating of the Safety, Pharmacokinetics and Pharmacodynamics of QL1205 and Lucentis® in Patients With Wet AMD
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: lucentis|DRUG: QL1205
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Ripening in Postmenopausal Women
Status: TERMINATED
Conditions: Stenosis of Cervix
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Augmentation Using Deepithelialized Free Gingival Graft Compared to Connective Tissue Graft in Management of Miller Class I and II Gingival Recession.
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Coronally advanced flap and subepithelial connective tissue graft|PROCEDURE: Coronally advanced flap and deepithelialized free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Two Anaesthetic Methods of Protecting Heart Tissue During Cardiac Surgery
Status: UNKNOWN
Conditions: Coronary Artery Bypass Surgery
Interventions: DRUG: Sevoflurane|PROCEDURE: High thoracic epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ADH300004 and 5-Fluorouracil in Locally Advanced, Recurrent, or Metastatic Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ADH300004
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomical Research of the Clavicular Pedicled Flap for Mandibular Reconstruction
Status: COMPLETED
Conditions: Mandibular Reconstruction|Maxillofacial Injuries
Interventions: OTHER: Osteoperiosteal pedicled clavicular flap for mandibular and facial bone reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Intubation：a Comparison of Different Endotracheal Tubes
Status: RECRUITING
Conditions: Intubation Complication
Interventions: DEVICE: Henan Tuoren Endotracheal Tube|DEVICE: Smiths Portex Tracheal Tubes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study to Assess the Safety, Pharmacokinetics, and Potential Effects of Amrubicin on the QT/QTc Interval in Cancer Patients With Advanced Solid Tumors.
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Amrubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Management Intervention for Living With Epilepsy (SMILE)
Status: COMPLETED
Conditions: Epilepsy
Interventions: BEHAVIORAL: Progressive muscle relaxation|BEHAVIORAL: Sham exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Varenicline (Chantix) Treatment for Waterpipe Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varinecline (Chantix)|DRUG: Placebo (for Varenicline)|BEHAVIORAL: Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga Effects on Heart Rate Variability and Electroencephalography
Status: COMPLETED
Conditions: Health Behavior|Quality of Life
Interventions: BEHAVIORAL: 1 month respiratory training|BEHAVIORAL: 1 month waiting period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: In-hospital Versus DAy Care Hysterectomy in Transgender Men
Status: COMPLETED
Conditions: Outpatient Hysterectomy in Transmen
Interventions: PROCEDURE: Outpatient hysterectomy|PROCEDURE: Inpatient hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Compare Emotional Changes In Subjects With Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Phobia
Interventions: DRUG: Placebo treatment during 8 weeks|DRUG: Paroxetine treatment during 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate Superiority of Decitabine Over Azacitidine in Subjects With Intermediate- or High-risk MDS.
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: decitabine|DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Otelixizumab for Adolescents and Adults With Newly Diagnosed Type 1 Diabetes Mellitus (Autoimmune): DEFEND-2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Otelixizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Periodontal Status and Failure Rates With Different Retainer Bonding Techniques Using One-step Adhesive
Status: COMPLETED
Conditions: Periodontal Inflammation
Interventions: PROCEDURE: Baseline periodontal measurements (T0)|PROCEDURE: Periodontal measurements (T1)|PROCEDURE: Periodontal measurements (T2)|PROCEDURE: Retainer failure rates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of the Candidate Vaccine MVA-SARS-2-S and a Booster Vaccination With a Licensed Vaccine Against COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: MVA-SARS-2-S vaccinations (days 0 & 28)|BIOLOGICAL: Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
Status: WITHDRAWN
Conditions: Dementia|Traumatic Brain Injury (TBI)|Mild Cognitive Impairment (MCI)|Chronic Traumatic Encephalopathy (CTE)|Post-traumatic Stress Disorder (PTSD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Trial of Autologous CLL B Cells Transduced to Express Chimeric CD154 (ISF35)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: ISF35
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Efficacy and Safety of CS20AT04 (Allogenic Bone Marrow-Derived Stem Cell) in Systemic Lupus Erythematosus Patients
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: CS20AT04 (allogenic bone marrow derived mesenchymal stem cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT