pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Avatrombopag for Temozolomide-induced Thrombocytopenia in Glioma (APATIT-G)
Status: RECRUITING
Conditions: Thrombocytopenia
Interventions: DRUG: Avatrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIOlogic Augmented Repair of Complex Anal Fistula Using Acellular Matrix and/or Autologous Platelet-rich Plasma
Status: RECRUITING
Conditions: Anal Fistula
Interventions: PROCEDURE: Surgery|OTHER: Platelet-rich plasma (PRP)|DEVICE: Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explorative Clinical Study on the Performance and Acceptance of New Intermittent Catheters in Healthy Volunteers
Status: COMPLETED
Conditions: Compliance, Patient
Interventions: DEVICE: Test product 2|DEVICE: Test product 3|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of TNX-102 SL Taken Daily in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: TNX-102 SL|DRUG: Placebo SL Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypopressive Exercises in Comparison With Routine Pelvic Floor Exercises in Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Hypopressive exercises|OTHER: Pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mandala Coloring on Anxiety and Quality of Life of Women in the Climacteric Period
Status: COMPLETED
Conditions: Anxiety|Climactericum
Interventions: OTHER: Mandala coloring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Camrelizumab Plus Chemotherapy in Combination With or Without Famitinib as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (BCTOP-T-N01)
Status: RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Camrelizumab Plus Chemotherapy and Famitinib|DRUG: Camrelizumab Plus Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salvage Therapy With Bevacizumab Plus Docetaxel and Cisplatin for Taiwanese Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Bevacizumab, docetaxel, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant in Patients HIV+ Supplemented With Microencapsulated of Red Pomegranate
Status: COMPLETED
Conditions: HIV Positive
Interventions: DIETARY_SUPPLEMENT: HIV+ MRPJ|DIETARY_SUPPLEMENT: HIV+ ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Pilot and Feasibility Study of the CALM Hearts Intervention
Status: COMPLETED
Conditions: Self-Compassion|Physical Inactivity|Cardiovascular Diseases
Interventions: BEHAVIORAL: Compassionate And Loving Mindset towards Heart Health Risk (CALM Hearts) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Bone Metastases
Interventions: BIOLOGICAL: Zoledronic acid|DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemia
Interventions: DRUG: Rosuvastatin 10 mg + Ezetimibe 10 mg and Rosuvastatin 20 mg + Ezetimibe 10 mg, according to clinical evaluation.|DRUG: Simvastatin 20 mg + Ezetimibe 10 mg and Simvastatin 40 mg + Ezetimibe 10 mg, according to clinical evaluation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Range Finding Study With Open-Label Extension to Evaluate the Safety of Oral LMI070/Branaplam in Early Manifest Huntington's Disease
Status: COMPLETED
Conditions: Early Manifest Huntington Disease
Interventions: DRUG: Branaplam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mindfulness Based Cognitive Therapy (MBCT) on for Insomnia and Mental Health of Prisoners
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|BEHAVIORAL: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of a Connected Application on the Follow-up of Patients Treated for Glial Lesions Operated
Status: UNKNOWN
Conditions: Quality of Life|Phone Use, Cell|Glial Scar
Interventions: DEVICE: Connected application arm|DEVICE: Unconnected arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Vonoprazan to Esomeprazole in Participants With Symptomatic GERD Who Responded Partially to a High Dose of Proton Pump Inhibitor (PPI)
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Vonoprazan|DRUG: Esomeprazole|DRUG: Esomeprazole Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Reduced Dentin Etching Time Using Universal Adhesives in the Quality of Cervical Lesions Restorations
Status: COMPLETED
Conditions: Non-carious Cervical Lesions
Interventions: PROCEDURE: Dentin Etching time for 5 seconds|DEVICE: Scotchbond Universal Plus; 3M|DEVICE: Gluma Universal Bond; Kulzer|PROCEDURE: Dentin Etching time for 15 seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabonomics of COPD and Transplanting of Faecal Bacteria in the Treatment of Its Malnutrition
Status: UNKNOWN
Conditions: Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: King Video Laryngoscope Versus Direct Laryngoscopy for Prehospital Intubation: A Randomized Controlled Trial
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: DEVICE: King Video Laryngoscope|DEVICE: traditional direct laryngoscopy (DL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AVT03 With Xgeva in Healthy Male Subjects
Status: COMPLETED
Conditions: This is a Phase I Study Conducted in Healthy Volunteers
Interventions: BIOLOGICAL: AVT03|BIOLOGICAL: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis
Status: COMPLETED
Conditions: Facial Angiofibroma
Interventions: DRUG: Rapamycin|DRUG: Calcitriol|DRUG: Rapamycin-calcitriol combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxycodone on Anxiety State in Painless Abortion
Status: NOT_YET_RECRUITING
Conditions: Abortion Complication
Interventions: DRUG: Fentanyl (as Citrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Pass Albumin Dialysis in Patients With Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Acute on Chronic Hepatic Failure|Hepatorenal Syndrome|Encephalopathy
Interventions: DEVICE: Single pass albumin dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Furmonertinib in Patients With Locally Advanced or Metastatic NSCLC With EGFR Exon 20 Insertion
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: Furmonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-home Telerehabilitation for Quadriplegic Hand Function
Status: COMPLETED
Conditions: Spinal Cord Injury|Quadriplegia|Tetraplegia
Interventions: PROCEDURE: Telerehabilitation of hand function|PROCEDURE: Conventional exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate One-to-one Peer Mentoring
Status: COMPLETED
Conditions: Injuries, Spinal Cord
Interventions: BEHAVIORAL: one-to-one peer mentoring|BEHAVIORAL: general peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Docetaxel Plus Cisplatin and 5-fluorouracil (TPF) Followed by Concomitant Chemoradiotherapy and Chemoradiotherapy Alone in Locally Advanced Squamous Cell Carcinoma of the Head and Neck Patients (SCCHNS)
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Docetaxel, cisplatin and 5-FU treatment followed by concomitant cisplatin, 5-FU and radiotherapy|DRUG: Concomitant cisplatin, 5-FU and radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren Syndrome
Status: COMPLETED
Conditions: Inflammation|Sjogren's Syndrome|Gland; Inflammation
Interventions: DEVICE: Superb Microvascular Imaging (SMI) (Toshiba)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: USFIB at the Inguinal Ligament for Total Hip Arthroplasty
Status: COMPLETED
Conditions: Post Surgical Pain
Interventions: DRUG: Single shot femoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Titration Study to Test Safety and Effects of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: CK-2017357|DRUG: Placebo|DRUG: Riluzole 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study Will Evaluate the Efficacy of AZD5423 in Patients With Mild Asthma Challenged With an Inhaled Allergen
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD5423|DRUG: Budesonide 200 microgram|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: R-21 Colorectal Cancer Screening (CRCS) Pilot Trial
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: CRCS patient decision aid (PtDA) video|BEHAVIORAL: Questionnaires|BEHAVIORAL: Essential Hypertension video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis
Status: COMPLETED
Conditions: Tuberculous Pericarditis
Interventions: DRUG: Prednisolone|BIOLOGICAL: Mycobacterium w immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 Administered On A Continuous Daily Dosing Schedule In Patients With Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Anaplastic|Enteropathy-Associated T-Cell Lymphoma|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Extranodal NK-T-Cell|Lymphoma, T-Cell, Peripheral
Interventions: BIOLOGICAL: Anti-Tumor Necrosis Factor (TNF) Receptor Superfamily Member 8 (CD30) Chimeric Antigen Receptor (CAR) T cells|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Gilteritinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Mycophenolate Mofetil in subjectswithSjogren's Syndrome
Status: UNKNOWN
Conditions: Sjogren's Syndrome
Interventions: DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dissonance Eating Disorder Prevention: Clinician Led, Peer Led vs Web Delivered
Status: COMPLETED
Conditions: Eating Disorder Prevention
Interventions: BEHAVIORAL: Peer-Led Group Intervention|BEHAVIORAL: Internet-Based Intervention|BEHAVIORAL: Clinician-Led Group Intervention|BEHAVIORAL: Education Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psoas Compartment Block Versus Fascia Iliaca Block After Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Bupivacaine|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: IMproving reModeling in Acute myoCardial Infarction Using Live and Asynchronous TElemedicine.
Status: UNKNOWN
Conditions: Left Ventricular Remodeling|Medication Adherence|Acute Coronary Syndrome
Interventions: OTHER: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Blue Light Filtering Intraocular Lenses on Daytime Levels of Melatonin
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: PROCEDURE: White Alcon IOL|PROCEDURE: Yellow Alcon IOL|PROCEDURE: White Hoya IOL|PROCEDURE: Yellow Hoya IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exploratory Trial to Evaluate the Safety and Immunogenicity of Menactra® and Menomune® Vaccines in Subjects ≥ 56 Years
Status: COMPLETED
Conditions: Meningococcal Infections|Meningococcal Meningitis
Interventions: BIOLOGICAL: Menomune®: A, C, Y, W-135 Meningococcal Polysaccharide|BIOLOGICAL: Menactra®: Polysaccharide Diphtheria Toxoid Conjugate|BIOLOGICAL: Menactra®: Polysaccharide Diphtheria Toxoid Conjugate|BIOLOGICAL: Menactra®: Polysaccharide Diphtheria Toxoid Conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Contrast-Enhanced Ultrasound
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Injuries|Physical Abuse|Accidental Fall|Motor Vehicle Injury
Interventions: DRUG: Contrast-Enhanced Ultrasound using Lumason
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BEFAST (Bubble-Enhanced FAST) for the Evaluation of Solid Organ Injury
Status: COMPLETED
Conditions: Abdominal Trauma
Interventions: DIAGNOSTIC_TEST: Focused Assessment with Sonography for Trauma (FAST)|DRUG: Bubble-Enhanced FAST (BEFAST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Study on Prognosis of Cardiac Resynchronized Therapy (CRT), Implantable Cardioverter Defibrillator (ICD) Implantation in Patients With Congestive Heart Failure (CHF)
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: PROCEDURE: ICD/CRT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Probing the Synergistic Effect of Pre-Biotics & Iron Fortificants in Anemic Subjects
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: COMBINATION_PRODUCT: Prebiotic + Iron Forificant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Platinum-Resistant Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: dexamethasone|DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Novel Technique of Analgesia Following Open Liver Resection
Status: COMPLETED
Conditions: Postoperative Pain|Liver Resection
Interventions: PROCEDURE: ropivacaine + iv PCA|PROCEDURE: saline and IV PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kochujang Pills on Improvement of Blood Lipids
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Kochujang Pills|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exhaled NO Based Treatment of Chronic Obstructive Pulmonary Disease (COPD), ICS/LABA Versus LAMA
Status: UNKNOWN
Conditions: COPD
Interventions: DRUG: fluticasone/salmeterol, tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Curcumin and Ginkgo for Treating Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo and ginkgo extract|DRUG: Curcumin and ginkgo extract|DRUG: Curcumin and ginkgo extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Filgrastim in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: prednisolone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vaginal Creams to Reduce Vaginal Erosion in Pessary Users
Status: WITHDRAWN
Conditions: Atrophy of Vagina|Vaginal Ulceration|Vaginitis
Interventions: DRUG: Estradiol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of a Diphtheria, Tetanus, Acellular Pertussis and Poliomyelitis Vaccine (REPEVAX) Followed by 2 Doses of a Diphtheria, Tetanus and Poliomyelitis Vaccine (REVAXIS) in Subjects of 40 Years of Age or Older
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Poliomyelitis|Pertussis
Interventions: BIOLOGICAL: Diphtheria, tetanus, polio and pertussis vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tivozanib + Enzalutamide in Adv Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Tivozanib|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute and Chronic Effects of Fruit Polyphenols on Chronic Disease (PPF)
Status: COMPLETED
Conditions: Nutritional and Metabolic Disease|Overweight
Interventions: DIETARY_SUPPLEMENT: Active Treatment Beverage|DIETARY_SUPPLEMENT: Placebo Treatment Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of The Spanner Temporary Prostatic Stent as an Alternative to a Urinary Catheter to Achieve Bladder Drainage in Men
Status: COMPLETED
Conditions: Urinary Retention
Interventions: DEVICE: The Spanner Temporary Prostatic Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Manual Therapy and Neuromuscular Training in the Management of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Manual therapy techniques|DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tangerine or Red Tomato Juice in Treating Patients With Prostate Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: dietary intervention (tangerine tomato juice)|DIETARY_SUPPLEMENT: dietary intervention (red tomato juice)|OTHER: questionnaire administration|OTHER: Correlative studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hexetidine and Chlorobutanol for Lesions Due to Prostheses
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: chlorobutanol, hexetidine|DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinician Counseling and Cultural Competency to Improve Hypertension Control and Therapy Adherence
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension
Interventions: BEHAVIORAL: Patient-centered Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Transesophageal Echocardiographic Evaluation of the Effect of Dexmedetomidine Infusion as an Adjuvant to General Anesthesia on the Cardiac Function
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine, Transesophageal echocardiography(TEE)|DRUG: Saline will be infused for 60 minutes at the same rates as dexmedetomidine group.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: 3 x 3 Factorial Trial of Telmisartan and Hydrochlorothiazide in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Hydrochlorothiazide|DRUG: Telmisartan + Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oral Nutritional Supplementation in Amyotrophic Lateral Sclerosis (ALS) Patients
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DIETARY_SUPPLEMENT: Oral nutritional supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FLT PET for Suspicious Findings on Mammography and Breast Ultrasound
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: 18F-FLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Use of Pressure Sensors in Functional Assessment and Treatment of Low Back Pain Patients
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: DEVICE: OhmTrak device.|OTHER: Outpatient Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study
Status: UNKNOWN
Conditions: Cancer|Cachexia; Cancer
Interventions: DIETARY_SUPPLEMENT: Over physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) - Year 1, 2009
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone® (intramuscular)|BIOLOGICAL: FluMist® (intranasal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Renal Replacement Therapy in the Setting of Orthotopic Liver Transplant
Status: WITHDRAWN
Conditions: Acute Kidney Injury|Liver Disease|Chronic Kidney Disease|End Stage Kidney Disease
Interventions: PROCEDURE: Renal replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Computerized Cognitive Rehabilitation in Chronic Stage Stroke
Status: COMPLETED
Conditions: Chronic Stroke|Cognitive Impairment
Interventions: OTHER: Guttmann, NeuroPersonalTrainer|OTHER: Ictus.online
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Intervention for Gut Function
Status: RECRUITING
Conditions: Gut Function
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ZEBOVAC (Ebola Vaccine Trial, Ad26.ZEBOV/MVA-BN-Filo)
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: DRUG: Ad26.ZEBOV/MVA-BN-Filo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Leukocyte-Rich PRP or Leukocyte-Free PRP in the Treatment of Hip Osteoarthritis
Status: RECRUITING
Conditions: Hip Osteoarthritis
Interventions: OTHER: Leukocyte Rich- PRP injection|OTHER: Leukocyte Poor- PRP injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors
Status: COMPLETED
Conditions: Anaplastic Oligoastrocytoma|Anaplastic Oligodendroglioma|Mixed Glioma|Oligoastrocytoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Etoposide Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mannitol|DRUG: Melphalan|OTHER: Quality-of-Life Assessment|DRUG: Sodium Thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: Bosinji|DRUG: Loxonine tab.|PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOMATULINE Autogel 90 mg IN DUMPING SYNDROME
Status: COMPLETED
Conditions: Dumping Syndrome
Interventions: DRUG: Lanreotide 90 mg slow release formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macro and Microcirculatory Effects of the Combination of Norepinephrine and Octreotide for the Treatment of Cirrhotic Patients With Hemorrhagic Shock
Status: WITHDRAWN
Conditions: Haemorrhagic Shock|Variceal Hemorrhage
Interventions: DRUG: Octreotide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulipristal Acetate in Symptomatic Uterine Fibroid
Status: TERMINATED
Conditions: Uterine Fibroid|Heavy Menstrual Bleeding
Interventions: DRUG: Ulipristal Acetate 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Status: WITHDRAWN
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory
Interventions: DRUG: Decitabine|DRUG: Venetoclax|DRUG: Navitoclax|DRUG: intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dilution and Prolonged Injection Time on Dexamethasone-induced Perineal Irritation
Status: UNKNOWN
Conditions: Adverse Effect
Interventions: DRUG: Dexamethasone|OTHER: Diluted dexamethasone 5ml|OTHER: Diluted dexamethasone 10ml|OTHER: Diluted dexamethasone 20ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Dexmetomidine Intrathecally and Intravenously Additionally to Spinal Anaesthesia, in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Neuromuscular Block
Interventions: DRUG: Levobupivacaine|DRUG: Dexmetomidine intravenously|DRUG: Normal Saline added intrathecally|DRUG: Normal Saline intrathecally|DRUG: Ringer's Lactate solution intravenously|DRUG: Dexmetomidine intrathecally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Steroids for Dysphagia
Status: WITHDRAWN
Conditions: Dysphagia|Cervical Spine Disease
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: MC-8XL low level laser device and Standard wound care|DEVICE: Sham laser device and Standard wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Suprainguinal Fascia Iliaca Block vs. Periarticular Injection for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia
Interventions: OTHER: Group Suprainguinal fascia iliaca block|OTHER: Group Periarticular Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of LIK066 on Glucose Absorption in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LIK066|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit (CPB)
Status: COMPLETED
Conditions: Heart Surgery
Interventions: DEVICE: Conventional 2-stage venous cannula|DEVICE: Conventional 3-stage venous cannula|DEVICE: Fenestrated 3-stage venous cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium
Status: COMPLETED
Conditions: Urinary Schistosomiasis|Schistosoma Haematobium
Interventions: BIOLOGICAL: Bilhvax vaccine (Sh28GST)|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Efficacy of Oral Vismodegib in Various Histologic Subtypes
Status: COMPLETED
Conditions: Basal Cell Carcinoma
Interventions: DRUG: vismodegib (150 mg PO daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vulvovaginal Atrophy Correction Using Neodymium Laser
Status: COMPLETED
Conditions: Postmenopausal Period|Vaginal Atrophy|Female Urogenital Diseases
Interventions: DEVICE: Laser Treatment|DRUG: Topical hormone estriol|DIAGNOSTIC_TEST: Сlinical blood analysis|DIAGNOSTIC_TEST: Сlinical urine test|DIAGNOSTIC_TEST: Vaginal smear|DIAGNOSTIC_TEST: Pelvic ultrasound|OTHER: Female Sexual Function Index|OTHER: The Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire|OTHER: Vulvovaginal Symptoms Questionnaire|DIAGNOSTIC_TEST: Vaginal Health Index|DIAGNOSTIC_TEST: Elastography (ultrasound investigation)|DIAGNOSTIC_TEST: Perineometry|OTHER: Visual Analogue Scale (VAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess Safety, Tolerability and Pharmacokinetics After Single Dose of AZD2516 to Japanese Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD2516|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents and Young Adults With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: OTHER: Sugar Sweetened Beverages (SSB)|OTHER: Hi GI|OTHER: Lo GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dry Needling Versus Instrumented Assisted Soft Tissue Mobilization In the Patient With Cervicogenic Treatment Headache
Status: UNKNOWN
Conditions: Cervicogenic Headache
Interventions: OTHER: dry needling|OTHER: instrumented assisted soft tissue mobilization|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones
Status: COMPLETED
Conditions: Cystinuria|Nephrolithiasis, Calcium Oxalate
Interventions: DRUG: Cystone|DRUG: Sugar Pill (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Stimulation as Add on Therapy to SCS toTreat Low Back Pain in FBSS
Status: COMPLETED
Conditions: Low Back Pain|Failed Back Surgery Syndrome|Neuropathic Pain
Interventions: DEVICE: SubQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis, Homozygous for the F508del CFTR Mutation
Interventions: DRUG: Placebo|DRUG: Lumacaftor Plus Ivacaftor Combination|DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Energy Regulation and Nutritional Status of Children: A Satiation Study
Status: COMPLETED
Conditions: Underweight|Stunting|Healthy
Interventions: BEHAVIORAL: High energy preload|BEHAVIORAL: Low energy preload
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between Unilateral Versus Bilateral Stenting for Malignant Hilar Biliary Obstruction to Use a LCD Stent
Status: WITHDRAWN
Conditions: Obstruction of Biliary Tree|Cholangiocarcinoma|Hepatocellular Carcinoma|Malignant Lymphadenopathy|Gall Bladder Cancer
Interventions: DEVICE: stent insertion|PROCEDURE: Endoscopic retrograde cholangiopancreatoscopy(ERCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton and Heavy Ion Beam Radiation vs. Photon Beam Radiation for Newly Diagnosed Glioblastoma.
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is There an Association Between Innate CD8+ T Cells and the Evolution of Tyrosine Kinase Inhibitor Resistance Mutations in Phi+ Hematological Malignancies.
Status: RECRUITING
Conditions: Leukemia|Myelogenous Leukemia|Chronic Leukemia|BCR-ABL Positive Acute Myeloid Leukemia
Interventions: GENETIC: Phenotyping of total and innate CD8+T cells by flow cytometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapy for Children With Advanced Stage High Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Topotecan, Cyclophosphamide, Cisplatin, Doxorubicin, Etoposide, Ifosfamide, Carboplatin|PROCEDURE: Peripheral Blood Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Low Frequency Frontal and Temporal rTMS Treatment in Chronic Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: Combined frontal and temporal rTMS|DEVICE: Temporal low frequency rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Motor Unit Abnormalities After Experimentally Induced Sensitization
Status: COMPLETED
Conditions: Central Sensitisation|Motor Disorders
Interventions: DRUG: Capsaicin Topical Cream (0.075%)|DEVICE: Delsys Trigno Galileo System|DEVICE: Excaliber, Natus Medical|OTHER: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots
Status: COMPLETED
Conditions: Lentigo Solar
Interventions: DEVICE: Prototypes (815-v1 001) to (815-v1 050)|DEVICE: Prototype (815-v1 051) to (815-v1 100)|DEVICE: Prototypes (815-v1 101) to (815-v1 150)|DEVICE: Prototypes (815-v1 151) to (815-v1 200)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SDX-105 in Combination With Rituxan for Patients With Relapsed Indolent or Mantle Cell Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: bendamustine and rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IntraopeRativE Use of periNeal Block for Hemorrhoidectomy
Status: UNKNOWN
Conditions: Hemorrhoidectomy|Pudendal Nerve
Interventions: PROCEDURE: perineal block with usage of one of solutions|DRUG: epinephrine + ropivacaine +saline|DRUG: epinephrine + saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Characterize the Effect of GS-5737 Enhancement of Mucociliary Clearance (MCC) in Healthy Subjects
Status: TERMINATED
Conditions: Cystic Fibrosis|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: GS-5737
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Clinical Consequences of Flutemetamol-PET-scanning
Status: TERMINATED
Conditions: Mild Cognitive Impairment|Alzheimer's Disease|Dementia
Interventions: DRUG: Flutemetamol (Vizamyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene
Status: RECRUITING
Conditions: Acute Myeloid Leukemia With KMT2A Rearrangement|Acute Myeloid Leukemia With NPM1 Mutation
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Cytarabine|DRUG: Daunorubicin|PROCEDURE: Multigated Acquisition Scan|DRUG: Revumenib|PROCEDURE: Transthoracic Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Topical 0.5% Levofloxacin to Reduce the Conjunctival Bacterial Flora Before Intraocular Surgery
Status: COMPLETED
Conditions: Conjunctival Bacterial Flora
Interventions: DRUG: 0.5% levofloxacin eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy for Stress Ulcer Prophylaxis Between the Patients Received Lansoprazole OD and Control Group Weaning From Mechanical Ventilator in Respiratory Care Center: a Randomized Control Trial
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: lansoprazole OD|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pregnancy-Related Hypertension: Adherence to a New Type of Monitoring
Status: COMPLETED
Conditions: Gestational Hypertension|Preeclampsia|Chronic Hypertension With Pre-Eclampsia Complicating Childbirth|HELLP Syndrome
Interventions: DEVICE: Home blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of Endostar in Combination With Chemotherapy of DF and Sequential Intensity Modulated Radiation Therapy for Patients With Advanced Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: endostar|RADIATION: intensity modulated radiation|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Atorvastatin Calcium Tablets, 80 mg of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin Calcium Tablets, 80 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study to Evaluate the Efficacy and Safety of MT921 in Subjects With Moderate to Severe Submental Fat
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: MT921|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT