pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Ticagrelor and Clopidogrel on Platelet Aggregation in Clopidogrel Resistance's Patients With CHD
Status: UNKNOWN
Conditions: Platelet Reactivity
Interventions: DRUG: Ticagrelor 90 mg|DRUG: Clopidogrel 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma
Status: TERMINATED
Conditions: Mesothelioma
Interventions: DRUG: LMB-100|DRUG: SEL-110
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anakinra on Insulin Secretion
Status: UNKNOWN
Conditions: Glucose Intolerance|Impaired Insulin Secretion|Diabetes Mellitus Type 2
Interventions: DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Endothelin Receptor Antagonism With Ambrisentan to Treat Hepatorenal Syndrome
Status: RECRUITING
Conditions: Hepatorenal Syndrome|Liver Cirrhosis|Acute Kidney Injury|Ascites Hepatic
Interventions: DRUG: Ambrisentan|DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "ESTIMATION Study" for Endocardial Mesenchymal Stem Cells Implantation in Patients After Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Heart Failure
Interventions: PROCEDURE: PCI and Stem Cells or Placebo injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Neurostimulation and Psychotherapy to Stop Worrying
Status: RECRUITING
Conditions: Active tDCS|Sham tDCS
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Administration of Pregabalin in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketogenic Intervention in Depression
Status: RECRUITING
Conditions: Depression|Ketosis
Interventions: OTHER: Ketogenic Diet|OTHER: NIH Toolbox|OTHER: gradCPT|OTHER: Resting-state fMRI|OTHER: Task-fMRI|OTHER: CGM/CKM|BIOLOGICAL: Blood Draw|OTHER: Sleep Monitoring|BIOLOGICAL: Ketone/Glucose Monitoring|OTHER: Body Composition|BEHAVIORAL: PHQ-9|BEHAVIORAL: WHO-5|BEHAVIORAL: SKID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuropsychological Assessment of Remediation for Cognitive Impairments in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenic Disorders
Interventions: OTHER: [Eco-Sz] Ecological Cognitive training program for schizophrenia spectrum disorder|OTHER: Recovery-Oriented Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Skin Changes in Head and Neck Cancer During Immuno-(Chemo-) And Radiotherapy With Erbitux® (HICARE)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Erbitux®|RADIATION: Fractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supervised Endurance Training Among Pulmonary Arterial Hypertension Patients
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Supervised endurance exercise training + Patient Education|OTHER: Home exercises + Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Affecting Methamphetamine and Opiates Drug Testing
Status: COMPLETED
Conditions: Opiates|Healthy
Interventions: DRUG: Vicks VapoInhaler|OTHER: Poppy seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects Gluten Intake on Body Composition, Energy Expenditure and Adipokine Profile in Non-celiac Women With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: gluten phase|DIETARY_SUPPLEMENT: placebo phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Ascending Dose, Single/Multiple Dosing, Food Effect Clinical Trial to Evaluate Pharmacokinetics, Safety and Tolerability in Healthy Subjects After Oral Administration of Gemigliptin (Phase I)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin 25mg|DRUG: Gemigliptin 50mg|DRUG: Gemigliptin 100mg|DRUG: Gemiglptin 50mg multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumor of Pancreas (Disorder)|Neuroendocrine Tumor Grade 1
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HistoSonics Investigational System for Treatment of Primary Solid Renal Tumors Using Histotripsy
Status: RECRUITING
Conditions: Renal Cancer|Tumor, Solid|Kidney Cancer|Tumor|Tumor, Benign|Kidney Neoplasms
Interventions: DEVICE: HistoSonics Investigational System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of HuangKui Capsule to Treat Diabetic Kidney Disease
Status: UNKNOWN
Conditions: Diabetic Kidney Disease
Interventions: DRUG: Placebo drug that simulates Irbesartan tablets|DRUG: irbesartan tablets|DRUG: Placebo drug that simulates HuangKui capsule|DRUG: HuangKui Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamified Rehab vs Take-home Packet Rehab for Non-specific Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-specific Low Back Pain
Interventions: OTHER: Leaderboard|OTHER: Take-home packet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous Anesthesia and Balanced Anesthesia on Flash Visual Evoked Potentials
Status: RECRUITING
Conditions: Brain Tumor Adult
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Distortion Banding on Outcome Measures in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Kinesio Taping|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Linzagolix in Female Subjects With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Renal Impairment|Healthy Participants
Interventions: DRUG: Linzagolix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cross-Education Of Contralateral Antagonists
Status: COMPLETED
Conditions: Muscle Strength Quantitative Trait Locus 1
Interventions: PROCEDURE: Experimental group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Effects of JNJ-54861911 on Electrocardiogram Intervals in Healthy Particiants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54861911-Therapeutic Dose|DRUG: JNJ-54861911 - Supratherapeutic Dose|DRUG: JNJ-54861911-Matched Placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Biomarkers for Diagnosis and Prognosis in CAA
Status: UNKNOWN
Conditions: Cerebral Amyloid Angiopathy|Intracranial Hemorrhages|Alzheimer Disease
Interventions: DRUG: 1. amyloid PET；2. T807 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selective Vagus Nerve Stimulation in Human
Status: COMPLETED
Conditions: Arterial Hypertension|Ischemic Heart Disease
Interventions: PROCEDURE: Selective vagus nerve stimulation|DEVICE: selective vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Teriparatide (rhPTH 1-34) Promote Fracture Healing in Proximal Humeral Fractures?
Status: COMPLETED
Conditions: Humeral Fracture
Interventions: DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)
Status: NOT_YET_RECRUITING
Conditions: Metastatic Microsatellite Stable Colorectal Carcinoma|Recurrent Colorectal Carcinoma|Stage III Colorectal Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Unresectable Colorectal Carcinoma
Interventions: PROCEDURE: Biopsy|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Therapeutic Autologous Dendritic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility and Effectiveness of Polygenic Risk Scoring (PRS) for Coronary Artery Disease (CAD)
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Polygenic Risk Score|Heart Diseases|Coronary Disease|Myocardial Infarction|Cardiovascular Diseases
Interventions: GENETIC: Disclosure of integrate risk score for coronary artery disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Cutaneous Lichen Planus
Status: COMPLETED
Conditions: Cutaneous Lichen Planus
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epidural Versus Wound Infusion Plus Morphine Bolus in Open Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Paracetamol|DRUG: Levobupivacaine wound infiltration|DRUG: Levobupivacaine epidural bolus|DRUG: Sufentanil epidural bolus|DRUG: Morphine|DEVICE: Epidural catheter placement|DEVICE: Wound infusion catheters placement|DRUG: Levobupivacaine plus sufentanil epidural infusion|DRUG: Levobupivacaine wound infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Restylane and Triamcinolone Acetonide Injections for the Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Intralesional Triamcinolone Acetonide 10 mg/mL (Kenalog-10)|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Treatment of L-DOPA-Induced Dyskinesia With Tianqi Pingchan Granule Combined With Amantadine
Status: UNKNOWN
Conditions: L-DOPA-Induced Dyskinesia
Interventions: DRUG: Tianqi Pingchan Granule Combined With Amantadine|DRUG: Placebo Combined With Amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Study of 64Cu-GRIP B for Patients Receiving CD19-directed CAR-T Therapy
Status: NOT_YET_RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: 64Cu-GRIP B|PROCEDURE: Positron Emission Tomography (PET)|PROCEDURE: Optional tumor biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Stem Cell Study for Adult TBI (Phase 2b)
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Injuries, Traumatic|Brain Injuries, Acute|TBI (Traumatic Brain Injury)
Interventions: BIOLOGICAL: Placebo Infusion|BIOLOGICAL: Autologous BMMNC Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Intervention Program: Tobacco Treatment for Patients at Risk for Lung Cancer (PIP)
Status: COMPLETED
Conditions: Smoking Cessation|Biofeedback
Interventions: BEHAVIORAL: personalized cessation care|BEHAVIORAL: bio feedback|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction
Status: COMPLETED
Conditions: Cocaine Addiction|Cocaine Dependence
Interventions: DRUG: Modafinil and PET (brain imaging)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
Status: RECRUITING
Conditions: Tendinopathy|Jumper's Knee
Interventions: OTHER: Resistance training for knee extensors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of AVP-923 in the Treatment of Central Neuropathic Pain in Multiple Sclerosis
Status: COMPLETED
Conditions: Central Neuropathic Pain|Multiple Sclerosis
Interventions: DRUG: AVP-923-45|DRUG: AVP-923-30|DRUG: AVP-923-20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dietary Fibres on Metabolic Health and the Gut Microbiome
Status: COMPLETED
Conditions: Diet|Healthy|Systemic Inflammatory Response
Interventions: DIETARY_SUPPLEMENT: Pectin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tianqi Capsule on Glucose Variability in Patients With Type 2 Diabetes.
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Tianqi capsule|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Tailored and Digital Approach to Address Equity and Support Well-being for Healthcare Workers in the Era of COVID
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Anxiety|Satisfaction|Well-being
Interventions: OTHER: Comprehensive Well-Being Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Iron Absorption From Naturally Dephytinized Legumes
Status: NOT_YET_RECRUITING
Conditions: Iron Deficiencies
Interventions: OTHER: soy protein concentrate-meat analog|OTHER: soy protein concentrate-meat analog_dephytinization|OTHER: Farinata|OTHER: Farinata_dephytinization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Fludarabine and Alemtuzumab or Cyclophosphamide Followed by Peripheral Blood Stem Cell Transplant or Alemtuzumab in Treating Patients With Advanced or Progressive Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Fludarabine|DRUG: Campath|PROCEDURE: Transplant|DRUG: Campath|DRUG: Fludarabine|DRUG: Campath|DRUG: Campath
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NIRS Directed Optimal Cerebral Perfusion Pressure on the Outcome of Aneurysmal Subarachnoid Hemorrhage Patients
Status: UNKNOWN
Conditions: Optimal Cerebral Perfusion Pressure on the Outcome of aSAH Patients
Interventions: DEVICE: Near-infrared spectroscopy (NIRS) and ICM+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Milking the Umbilical Cord on Systemic Blood Flow
Status: COMPLETED
Conditions: Abnormal Vascular Flow
Interventions: PROCEDURE: Umbilical Cord Milking|PROCEDURE: Immediate Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: BEHAVIORAL: Dietary Caffeine reduction|DRUG: Anticholinergic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (CB-01-02/01) Randomized Placebo Controlled Trial of Budesonide-multi-matrix System (MMX™) 6 mg and 9 mg in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Blood sampling, endoscopy|DRUG: budesonide-MMX® 6 mg|DRUG: budesonide-MMX® 9 mg|DRUG: Placebo|DRUG: Asacol® 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mineralocorticoid Antagonism to Stop Progression of Atrial Fibrillation (MONITOR-AF) Study
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Spironolactone 25mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: a Study in Subjects With Otoferlin Mutation-related Hearing Loss Using RNA Base-eDiting Therapy(SOUND)
Status: NOT_YET_RECRUITING
Conditions: Congenital Hearing Loss
Interventions: GENETIC: HG205
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of a Foot Length Card to Improve Careseeking Practices of Vulnerable Newborns in Sarlahi District, Nepal
Status: COMPLETED
Conditions: Low Birth Weight Babies|Preterm Babies
Interventions: BEHAVIORAL: Footlength Card
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metabolic Effects of Accurate Blood Sugar Results and Education in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Use and interpretation of blood glucose results|DRUG: Insulin dosing based on SMBG chart and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Problematic Decision-Making and Adolescent Weight Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight Adolescents|Overweight or Obesity|Impulsive Behavior|Overeating
Interventions: BEHAVIORAL: Weight loss treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis
Status: RECRUITING
Conditions: Light Chain (AL) Amyloidosis
Interventions: BIOLOGICAL: NXC-201 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dysregulation of Core Body Temperature on Sleep in Patients With Hypohidrotic Ectodermal Dysplasia
Status: COMPLETED
Conditions: Hypohidrotic Ectodermal Dysplasia
Interventions: OTHER: Actigraphy|OTHER: Recording of proximal and distal skin temperature and temperature of the bedroom|OTHER: Questionnaires assessing subjective sleep quality|OTHER: Sweat test|OTHER: Urine melatonin assay|OTHER: Polysomnography|OTHER: Standardized psychological and neuropsychological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transpulmonary Pressure in Right Ventricle Protection of ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Acute Cor Pulmonale
Interventions: PROCEDURE: mechanical ventilation strategy guided by transpulmonary pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Oral Chronic Graft-versus-host Disease With Human Umbilical Cord Mesenchymal Stem Cell Dressing
Status: RECRUITING
Conditions: Mesenchymal Stem Cells
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HCL Insulin Delivery System on Glycemic Control in Patients With T1D
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Tandem t:slim X2 with hybrid closed loop system Control IQ, glucose sensor: Dexcom G6|DEVICE: MiniMed 780G, with hybrid closed loop system SmartGuard, sensor Guardien 4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: brentuximab vedotin|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of S-1 Plus LV for Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: S-1 plus LV (The combination therapy of S-1 and Leucovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus
Status: NOT_YET_RECRUITING
Conditions: Invasive Candidiasis|Invasive Aspergillosis
Interventions: DRUG: Amphotericin B cholesteryl Sulfate Complex for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteria
Status: COMPLETED
Conditions: Bronchitis, Chronic
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing QLB Type I Block to Intraperitoneal Instillation Added to Wound Infiltration for Postoperative Cesarian Pain
Status: RECRUITING
Conditions: Analgesia
Interventions: PROCEDURE: Wound infiltration (LWI) + Intraperitoneal local anaesthetic (IPLA) instillation|PROCEDURE: Group QUADRATUS LUMBORUM BLOCK (QLB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, and Pharmacokinetics of INE963 in Healthy Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: INE 963|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Of Iodine I 131 Tositumomab Therapeutic Regimen Versus Ibritumomab Tiuxetan Therapeutic Regimen
Status: WITHDRAWN
Conditions: Lymphoma, Small Cleaved-Cell, Follicular|Lymphoma, Large-Cell, Follicular|Lymphoma, Follicular|Lymphoma, Non-Hodgkin
Interventions: DRUG: Ibritumomab Tiuxetan|DRUG: Iodine I 131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Ankylosing Spondylitis (AS)
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: Human umbilical cord-derived MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fast-Track Eligibility and Hospital Discharge for Outpatient Lumbar Discectomy
Status: COMPLETED
Conditions: Lumbar Disc Disease|Post-Op Complication
Interventions: OTHER: Modified Aldrete Scoring System (mASS)|OTHER: White's Fast-Track Scoring System (WFTSS)|OTHER: SPEEDS criteria
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of 68Ga Labeled HER2 Affibody Analogues
Status: UNKNOWN
Conditions: HER2-positive Breast Cancer and Gastric Cancer
Interventions: DRUG: 68Ga labeled HER2 Affibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long Term Results of Surgical and Percutaneous Double Orefices Mitral Repair in Patient With p2 Prolapse Causing Degenerative Mitral Regurgitation
Status: COMPLETED
Conditions: Degenerative Mitral Valve Disease|Mitral Regurgitation
Interventions: PROCEDURE: Central edge-to-edge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Safety and Efficacy of Durvalumab in Combination With Paclitaxel in Metastatic Triple Negative Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Combined Botulinum Toxin A Injection and Gastric Balloon Implantation in Obesity Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: gastric balloon implantation|PROCEDURE: botulinum toxin A injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Collect in a Real-world populatIon Data on the Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Hidradenitis Suppurativa (HS) in Routine Clinical Practice in the Russian Federation
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: OTHER: Secukinumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Clinical Study of SB-480848 in Dyslipidemic Patients
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: SB480848 40mg EC Tablet|DRUG: SB480848 80mg EC Tablet|DRUG: SB480848 160mg EC Tablet|DRUG: SB480848 Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CPAP in Patients With Severe Obesity After Anesthesia
Status: NOT_YET_RECRUITING
Conditions: Obesity, Abdominal|Anesthesia Morbidity|Apnea, Obstructive Sleep|Atelectases, Postoperative Pulmonary|Ventilator Lung
Interventions: DEVICE: Recruitment/ITP-CPAP (Intervention A)|DEVICE: Standard CPAP (Intervention B)|DEVICE: Atmospheric Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of TAK-442 in Subjects Undergoing Total Knee Replacement
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: TAK-442|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcome Measures of Pulsed Radiofrequency of the Genicular Nerves When Performed With and Without Concomitant Local Corticosteroid Administration
Status: UNKNOWN
Conditions: Knee Pain Chronic
Interventions: DEVICE: pulsed radiofrequency modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mepolizumab Compared to Placebo on Airway Physiology in Patients With Eosinophilic Asthma: MEMORY Study
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Mepolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Education on Anxiety and Activities of Daily Living
Status: COMPLETED
Conditions: Postoperative Anxiety|Mobile Education|Patient Education|Anxiety|Activities of Daily Living
Interventions: OTHER: e-Mobile Application Patient Education for Patients with Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation
Status: UNKNOWN
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: Netarsudil Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Extubation for Patients With Acute Hypoxemic Respiratory Failure
Status: WITHDRAWN
Conditions: Mechanical Ventilation|Corona Virus Infection
Interventions: DEVICE: Helmet non-invasive ventilation (NIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of IFN-γ on Innate Immune Cells
Status: COMPLETED
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: Administration of drug (Interferon-gamma 1-b) subcutaneously
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis|Apical Periodontitis
Interventions: DEVICE: Multisonic vs Sonic activation of irrigants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: BIOLOGICAL: supaglutide injection+metformin|OTHER: placebo+metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study ADI-PEG 20 Plus Pembrolizumab in Advanced Solid Cancers
Status: TERMINATED
Conditions: Advanced Solid Cancers
Interventions: DRUG: ADI PEG20|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacokinetics, Safety, and Immunogenicity Study of Abatacept Administered Subcutaneously to Treat Rheumatoid Arthritis in Japanese Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Intravenous (IV) abatacept|DRUG: Subcutaneous (SC) abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conserving Surgery in Inflammatory Breast Cancer After Neoadjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Breast Cancer
Interventions: PROCEDURE: Breast conserving surgery|PROCEDURE: Radical modified mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theta Burst Stimulation in Young Adults With Depression
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Intermittent Theta Burst Stimulation|DEVICE: Continuous Theta Burst Stimulation|DEVICE: Sham Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-arrhythmic Medication v. MRI-Merge Ablation in the Treatment of Ventricular Tachycardia
Status: WITHDRAWN
Conditions: Ventricular Tachycardia
Interventions: PROCEDURE: MRI guided VT ablation|DRUG: Increased dose of amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-part, Single-dose, Randomized Study to Evaluate the Safety of Supra-therapeutic Doses of RO7033877 and to Investigate the Effect of RO7033877 on the QTc Interval
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Part 1: SAD RO7033877|DRUG: Part 1: SAD placebo|DRUG: Part 2: Treatment A, RO7033877|DRUG: Part 2: Treatment B, RO7033877|DRUG: Part 2: Treatment C, moxifloxacin|DRUG: Part 2: Treatment D, RO7033877 and moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Dose Escalation Study of BIBF 1120 Together With Paclitaxel and Carboplatin in Patients With Advanced Stage Non-small-cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BIBF 1120|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study on the Safety and Reactogenicity of a Single Dose of Monovalent High-dose Inactivated Poliovirus Type 2 Vaccine (m-IPV2 HD) Given Intramuscularly Compared to Standard Trivalent Inactivated Poliovirus Vaccine (IPV) in Healthy Adults
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: a single dose of monovalent high-dose inactivated poliovirus type 2 vaccine (m-IPV2 HD)|BIOLOGICAL: a single dose of the standard trivalent inactivated poliovirus vaccine (IPV)(Imovax Polio®).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Elopement Prevention and Safety Training Program
Status: COMPLETED
Conditions: Elopement|Autism Spectrum Disorder
Interventions: BEHAVIORAL: Universal Safety Measures Module (All participants)|BEHAVIORAL: Proximity Training Module (Bolting Prevention Participants)|BEHAVIORAL: Check-In Training Module (Wandering Prevention Participants)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluating Acupuncture Relationship With the Catecholaminergic Pathway
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Electroacupuncture|DRUG: Diclofenac sodium|OTHER: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doxercalciferol in Treating Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DIETARY_SUPPLEMENT: doxercalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cediranib (AZD2171, RECENTIN™) in Metastatic or Recurrent Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Cediranib|DRUG: Cediranib Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Turkish Version of Mini Osteoarthritis Knee and Hip Quality of Life Questionnaire
Status: COMPLETED
Conditions: Knee Osteoarthritis|Hip Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Turkish version of Mini Osteoarthritis Knee and Hip Quality of Life Questionnaire|DIAGNOSTIC_TEST: Nottingham Health Profile|DIAGNOSTIC_TEST: Short form 36|DIAGNOSTIC_TEST: Western Ontario and McMaster
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Adalimumab for the Maintenance of Clinical Remission in Japanese Subjects With Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delafloxacin Versus Vancomycin and Aztreonam for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin and Subcutaneous Tissue Bacterial Infections
Interventions: DRUG: Delafloxacin|DRUG: Vancomycin|DRUG: Aztreonam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Parkinson Disease|Healthy Volunteers
Interventions: BEHAVIORAL: 3 months exercise intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Epidural Block vs. Rectus Sheath Block on Postoperative Pulmonary Function
Status: COMPLETED
Conditions: Abdominal Surgeries
Interventions: OTHER: Thoracic epidural analgesia (TEA)|OTHER: Rectus sheath catheter block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Lurasidone in Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Lurasidone tablets|DRUG: Risperidone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Informed Palliative Care in Nursing Homes Through the interRAI Palliative Care Instrument
Status: UNKNOWN
Conditions: Nursing Home Residents With Palliative Care Needs
Interventions: OTHER: interRAI PC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Immunotherapy Study of BMS-986310 Administered Alone and in Combination With Nivolumab in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: BMS-986310|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers
Status: NOT_YET_RECRUITING
Conditions: Alcoholic Intoxication|Automobile Accident|Cannabis
Interventions: BEHAVIORAL: Policy and Training Intervention|BEHAVIORAL: Usual and Customary Policy and Training (UC-PT) (Control) Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Antibody Response to High-Dose Seasonal Influenza Vaccination in Patients With Myeloid Malignancy Receiving Chemotherapy and Healthy Volunteers
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: Trivalent Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous/Nonmalignant Condition
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclosporine|DRUG: methylprednisolone|DRUG: prednisone|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs
Status: RECRUITING
Conditions: Angina Pectoris, Variant|Angina Pectoris; Spasm-Induced|Angina Pectoris With Normal Coronary Arteriogram
Interventions: DIAGNOSTIC_TEST: Acetylcholine rechallenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Access Study of Trametinib for Subjects With Advanced Unresectable (Stage IIIc) or Distant Metastatic (Stage IV) BRAF V600E/K Mutation Positive Cutaneous Melanoma
Status: NO_LONGER_AVAILABLE
Conditions: Melanoma
Interventions: DRUG: Trametinib|DRUG: Dabrafenib
Study Type: EXPANDED_ACCESS
Clinical trial: Latinos Kick Buts: Mobile Engagement and Cessation Support for Latinos Who Smoke
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: One cycle|BEHAVIORAL: 4 cycles|BEHAVIORAL: 5 Dollar Incentive|BEHAVIORAL: Raffle Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality, External Cold and Vibration to Children During IM Injection on Pain, Fear and Anxiety
Status: UNKNOWN
Conditions: Procedural Pain|Fear|Procedural Anxiety|Child, Only
Interventions: BEHAVIORAL: Virtual Reality|BEHAVIORAL: Local cold-vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Sequential Multiple Ascending Dose Study of the Safety and Pharmacokinetics of Eslicarbazepine Acetate in Adult Healthy Volunteers
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Placebo|DRUG: BIA 2-093 3000 mg once daily|DRUG: BIA 2-093 3600 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring To Identify Worsening Heart Failure The REMOTI-HF Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Arrythmia
Interventions: OTHER: HeartLogic or TriageHF Algorithms for implantable devices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: 18-Week, Randomized, Double-blind, Placebo Controlled, Forced Titration Study of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Technosphere Insulin|DRUG: Technosphere Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Acute Renal Injury During Partial Nephrectomy Using Neutrophil Gelatinase-associated Lipocalin (NGAL): Prospective Comparative Study Between Open, Video-assisted Minilaparotomy, Laparoscopic, and Robotic-assisted Laparoscopic Surgery
Status: COMPLETED
Conditions: the Patients With Partial Nephrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p