pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Impact of the 'Reserved Therapeutic Space' Nursing Intervention: an Intervention Study in Acute Mental Health Units
Status: COMPLETED
Conditions: Nurse-Patient Relations|Psychiatric Hospitalization
Interventions: BEHAVIORAL: Reserved Therapeutic Space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Two-Part Study of Sativex® Oromucosal Spray for Relieving Uncontrolled Persistent Pain in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Pain|Advanced Cancer
Interventions: DRUG: Nabiximols|DRUG: Placebo (GA-0034)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Compare the Addition of Topaz Micro Debridement to the Standard of Care Surgery
Status: COMPLETED
Conditions: Greater Trochanteric Pain Syndrome|Hip Pain Chronic
Interventions: DEVICE: Topaz|PROCEDURE: Iliotibial band release and trochanteric bursectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Platelet Reactivity After TAVI: A Multicenter Pilot Study
Status: COMPLETED
Conditions: Severe Aortic Valve Stenosis|Transcatheter Aortic Valve Implantation|Transcatheter Aortic Valve Replacement
Interventions: DRUG: Ticagrelor 90 mg twice per day during three months following TAVI|DRUG: Aspirin 100 mg plus Clopidogrel 75 mg daily during three months following TAVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Crossbite Correction - a Randomized Study
Status: RECRUITING
Conditions: Malocclusion|Crossbite
Interventions: DEVICE: Early crossbite correction with Q-H Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia in Patients With Mitochondrial Disease
Status: TERMINATED
Conditions: Mitochondrial Diseases
Interventions: DRUG: Sevoflurane|DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Investigator Initiated, Randomized, Double-blinded, Placebo-controlled Clinical Trial to Evaluate the Safety, Immunogenicity and Efficacy of the Recombinant Two-component COVID-19 Vaccine (CHO Cell) in Adults Aged 18 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Prevention of COVID-19 Caused by SARS-CoV-2
Interventions: BIOLOGICAL: randomized, double-blinded, placebo-controlled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Trial of Improving Care for Underserved Asian Americans Infected With HBV
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BEHAVIORAL: PNMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Fibrin Glues for Fistulas Closure
Status: COMPLETED
Conditions: Enterocutaneous Fistulas|Intra-abdominal Infection
Interventions: PROCEDURE: Autologous platelet-rich fibrin glue (PRFG)|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.
Status: COMPLETED
Conditions: Placental Insufficiency|NEC - Necrotizing Enterocolitis|Newborn, Premature|Feeding Disorder Neonatal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New Approaches to Improve Coverage and Compliance of Antimalarial Treatment for Pregnant Women in Rural Africa
Status: COMPLETED
Conditions: Malaria in Pregnancy
Interventions: DRUG: sulfadoxine-pyrimethamine|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Second Study on Cardio-neuromodulation in Humans
Status: COMPLETED
Conditions: Cardiac Disease|Syncope|Syncope, Vasovagal|Sick Sinus Syndrome
Interventions: DEVICE: radio-frequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Functional Therapy for Chronic Shoulder Pain: Pilot and Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Chronic Shoulder Pain|Exercise Therapy|Psychosocial Rehabilitation
Interventions: OTHER: Cognitive Functional Therapy|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Performance and Safety of GP0045 for Correction of Moderate to Severe Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Fold|Safety
Interventions: DEVICE: GP0045|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Testosterone Treatment on Embryo Quality
Status: UNKNOWN
Conditions: Primary Ovarian Insufficiency|Female Infertility Due to Diminished Ovarian Reserve
Interventions: DRUG: Testosterone cream (0.5mg per gram)|DIETARY_SUPPLEMENT: DHEA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Efficacy, Tolerability, and Safety of Intranasal Granisetron for Chemo-Induced Nausea and Vomiting
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Intranasal granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pressure Offloading Injectible System With the Use of Juvederm Voluma in the Foot
Status: UNKNOWN
Conditions: Metatarsalgia|Hyperkeratotic Callus|Corns|Fat Pad Syndrome
Interventions: DEVICE: Juvederm Voluma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins
Status: ACTIVE_NOT_RECRUITING
Conditions: Varicose Veins of Lower Limb|Varix|Vascular Diseases|Leg Edema
Interventions: DRUG: "Venarus®" (diosmin and hesperidin)|PROCEDURE: Endovenous laser ablation (EVLA) with miniphlebectomy|OTHER: Elastic compression|OTHER: Evaluation of biomarkers of venous wall remodeling (fibronectin, PAI-1, vimentin, vWF, CD31), venous symptoms and severity scores
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Oral Dexamethasone to Improve Recovery After Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Oral dexamethasone|DRUG: Ondansetron|OTHER: Gelatin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Capecitabine, and Erlotinib in Treating Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: erlotinib hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Effects of Nasal Nitric Oxide Measurements Are Associated With Atopy Status in Chronic Nasal Inflammation
Status: COMPLETED
Conditions: Hypersensitivity|Rhinitis|Respiratory Tract Diseases|Nasal Polyps|Nitric Oxide
Interventions: DEVICE: nasal nitric oxide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery Occlusion
Status: WITHDRAWN
Conditions: Nervous System Disorders|Cerebral Artery
Interventions: DRUG: rt-PA|DRUG: tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Nanoscaffold Augmentation in Rotator Cuff Repair: Clinical Outcome and Ultrasound Assessment of Healing Rates and Vascularity
Status: WITHDRAWN
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Syndrome of Shoulder and Allied Disorders
Interventions: DEVICE: Rotium nanoscaffold|PROCEDURE: Control arm rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Liver Fibrosis Due to NASH
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: SIM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric on Pulmonary Functions in Post Covid -19 Patients.
Status: COMPLETED
Conditions: Post COVID-19 Patients
Interventions: DEVICE: hyperbaric oxygen therapy|DEVICE: breathing exercise|DRUG: medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Nerve Stimulation to Improve Sleep
Status: COMPLETED
Conditions: Insomnia|Sleep|Sleep Disorders, Circadian Rhythm
Interventions: DEVICE: VeNS|DEVICE: Placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel in Men 75 Years of Age or Older With Castration-Resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Castrate-resistant Metastatic Prostate Cancer
Interventions: DRUG: Cabazitaxel|DRUG: Prednisone|DRUG: Granulocyte colony-stimulating factor (G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medication Treatment for Opioid Use Disorder in Expectant Mothers: Conceptual Model Assessments Sub-study
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-Related Disorders|Drug Addiction|Pregnancy Related|Substance Abuse|Drug Abuse|Neonatal Abstinence Syndrome|Neonatal Opioid Withdrawal Syndrome|Drug Abuse in Pregnancy
Interventions: DRUG: Buprenorphine Injection|DRUG: Buprenorphine Sublingual Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: SPY Elite Imaging|DRUG: Indocyanine Green|DRUG: Isosulfan blue|DRUG: 99technetium-sulfur colloid radiolabel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: VISSIT Intracranial Stent Study for Ischemic Therapy
Status: TERMINATED
Conditions: Ischemic Stroke|Transient Ischemic Attack
Interventions: DEVICE: Pharos Vitesse Neurovascular Stent System (Stent implantation) + Medical therapy (Aspirin and Clopidogrel)|DRUG: Aspirin and Clopidogrel (Medical therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Pembrolizumab in Resectable Mucosal Melanoma
Status: UNKNOWN
Conditions: Mucosal Melanoma|Neoadjuvant Treatment
Interventions: DRUG: Lenvatinib, Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PIEB-PCEA Versus CEI-PCEA for Labor Analgesia in Nulliparous
Status: COMPLETED
Conditions: Pregnancy
Interventions: DEVICE: Release analgesia by CADD SMITHS PCEA pump|DEVICE: Release analgesia by CADD SMITHS PIEB pump|DRUG: Levobupivacaine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder|Pervasive Developmental Disorder|Asperger's Disorder
Interventions: DEVICE: Groundskeeper
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Medium Frequency Electrotherapy in the Treatment of OAB, LUTS and Pelvic Pain
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Lower Urinary Tract Symptoms|Pelvic Pain
Interventions: OTHER: Medium frequency electrotherapy (interferential currents)|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmenopausal Estrogen/Progestin Interventions (PEPI)
Status: COMPLETED
Conditions: Bone Diseases|Cardiovascular Diseases|Coronary Disease|Diabetes Mellitus|Heart Diseases|Hypercholesterolemia|Hypertension|Myocardial Ischemia|Osteoporosis|Thrombosis|Postmenopause
Interventions: DRUG: estrogens, conjugated|DRUG: medroxyprogesterone|DRUG: progesterone|DRUG: estrogen replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Reducing Mortality in Adults With Advanced HIV Disease (REVIVE)
Status: RECRUITING
Conditions: HIV Disease Progression
Interventions: DRUG: Azithromycin Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation and Chemotherapy With Ipilimumab Followed by Nivolumab for Patients With Stage III Unresectable Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: RADIATION: Thoracic Radiotherapy|DRUG: Platinum Based Chemotherapy|DRUG: ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care
Status: COMPLETED
Conditions: Antibiotic Initiation|Antibiotic Duration
Interventions: BEHAVIORAL: Dynamic/Interactive vs. Static/Paginated Report|BEHAVIORAL: LTC Physicians Enrolled vs. Not Enrolled in Reports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrium Immunomodulation by in Utero Administration of Peripheral Blood Mononuclear Cells
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Intrauterine administration of hCG-activated peripheral blood mononuclear cells|PROCEDURE: Intrauterine administration of sperm washing medium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Screening for Atrial Fibrillation in Patients With Cancer: A Pilot Randomized Controlled Clinical Trial
Status: RECRUITING
Conditions: Cancer
Interventions: DIAGNOSTIC_TEST: 30-second ECG using the Kardia Mobile|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A 16 Week Evaluation of the Novartis Health Management Tool (HMT) in Age Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age Related Macular Degeneration (AMD)
Interventions: OTHER: Health Management Tool (HMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Subclinical Propionibacterium Acnes Infection Estimation in the Intervertebral Disc (SPInE-ID)
Status: COMPLETED
Conditions: Infection|Intervertebral Disc Herniation|Propionibacterium Infection|Spinal Diseases|Discitis
Interventions: OTHER: Microdiscectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lexapro®'s Efficacy After Dose Escalation in Remission Study
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: escitalopram|DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilator-associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation
Status: RECRUITING
Conditions: Ventilator Associated Tracheobronchitis|Tracheobronchitis
Interventions: OTHER: Clinical observation without antibiotic therapy for VAT|OTHER: 7 day antibiotic course for VAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fractional Carbon Dioxide Laser: A Novel Therapeutic Option for Lichen Simplex Chronicus
Status: NOT_YET_RECRUITING
Conditions: Lichen Simplex Chronicus
Interventions: DRUG: Betamethasone Valerate 0.1% Cream|DEVICE: SmartXide® fractional carbon dioxide laser|DRUG: Vaseline Topical Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of the Routine Distal Transradial Approach
Status: COMPLETED
Conditions: Vascular Access Complication|Radial Artery|Coronary Artery Disease|Puncture|Coronary Angiography
Interventions: OTHER: distal radial artery acess side|OTHER: conventional radial artery acess side
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Mirror Therapy and Cognitive Therapeutic Exercise in Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Hemiparesis
Interventions: BEHAVIORAL: Mirror therapy|BEHAVIORAL: Cognitive therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy
Status: TERMINATED
Conditions: Periodontitis
Interventions: DRUG: Doxycycline|DRUG: Placebo|PROCEDURE: modified/simplified papilla preservation flap; scaling|BIOLOGICAL: Prefgel/Emdogain|DRUG: 0.12% chlorhexidine gluconate solution|DRUG: Ibuprofen 400 mg (if necessary)|DRUG: 1% chlorhexidine gluconate gel (if necessary)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training to Enhance Brain Concordance During Acupuncture
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: OTHER: Electroacupuncture|BEHAVIORAL: Cognitive Training|BEHAVIORAL: Education Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Disorder; Breathing-Related|Central Apnea|Neuromuscular Diseases|Obstructive Sleep Apnea
Interventions: DEVICE: Transcutaneous CO2 monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MOD-4023 (Long-Lasting Human Growth Hormone (hGH)) Study in Growth Hormone Deficient Adults (GHDA)
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: MOD-4023|DRUG: MOD-4023|DRUG: MOD-4023|DRUG: MOD-4023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Age-Related Effects of THC
Status: COMPLETED
Conditions: Tolerance|Adolescent Behavior|THC
Interventions: DRUG: Dextrose|DRUG: Dronabinol|DRUG: Dronabinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of PET/MRI Using a Somatostatin Analog Tracer as a Novel Approach to Detecting Pathology in High Risk TB-exposed Contacts
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary
Interventions: RADIATION: FDG ligand|RADIATION: DOTANOC ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleep Disturbance,Physical and Mental Fatigue on Mechanical Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Mechanical Neck Pain
Interventions: OTHER: Demographic data of the individuals were recorded. All participants completed NDI, Chalder Fatigue Scale (CFS) and Pittsburgh Sleep Quality Index (PSQI).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WEE1 Inhibitor With Cisplatin and Radiotherapy: A Trial in Head and Neck Cancer
Status: COMPLETED
Conditions: Hypopharynx Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma|Larynx Cancer
Interventions: DRUG: AZD1775|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Chronic Pain|Scleroderma
Interventions: DRUG: Ozone|DRUG: methylprednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subpectoral Plexus Block With Multi-level TPVB for Surgical Anesthesia During Primary Breast Cancer Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: PROCEDURE: Subpectoral plexus block (low dose)|PROCEDURE: Subpectoral plexus block (High dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Septic Shock
Interventions: DRUG: IgM enriched Immunoglobulins
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nivolumab, BMS-936558 in Combination With Relatlimab, BMS-986016 in Patients With Metastatic Melanoma Naïve to Prior Immunotherapy in the Metastatic Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Relatlimab|DRUG: Nivolumab|DRUG: Relatlimab + Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (TDCS) for Facilitating Swallowing Improvement After an Acute Unilateral Hemispheric Stroke
Status: COMPLETED
Conditions: Dysphagia
Interventions: OTHER: tDCS|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial To Evaluate Two Antibiotics For The Treatment Of Acute Exacerbation Of Chronic Bronchitis (AECB)
Status: COMPLETED
Conditions: Chronic Bronchitis
Interventions: OTHER: Moxifloxacin Placebo|DRUG: Moxifloxacin|OTHER: Azithromycin SR Placebo|DRUG: Azithromycin SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Paracetamol in the Treatment of Non-severe Malaria in Children in Guinea-Bissau
Status: UNKNOWN
Conditions: Malaria|Falciparum
Interventions: DRUG: acetaminophen (paracetamol)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban
Status: COMPLETED
Conditions: Anticoagulant Reversal|Reversal of Edoxaban Induced Anticoagulation
Interventions: DRUG: PER977, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Amifampridine Phosphate for the Treatment of Congenital Myasthenic Syndromes
Status: COMPLETED
Conditions: Myasthenic Syndromes, Congenital
Interventions: DRUG: amifampridine phosphate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Using Augmented Reality (AR) Simulation System to Train Foreign Care Workers.
Status: RECRUITING
Conditions: Oral Dryness and Saliva Altered|Oral Manifestations|Swallowing Disorder
Interventions: DEVICE: oral care augmented reality (AR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Effects of Lumacaftor/Ivacaftor (LUM/IVA) on Exercise Tolerance in Subjects With Cystic Fibrosis (CF), Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: LUM/IVA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Oxycodone/Naloxone (Targin®) in Persistent Moderate to Severe Low Back Pain Following NSAIDs Treatment
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Brand Name: Targin®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Causal Lesion Network Guided Treatment of Bipolar Mania With Transcranial Electrical Stimulation
Status: RECRUITING
Conditions: Bipolar Disorder|Schizo Affective Disorder
Interventions: DEVICE: High-Definition Transcranial Electrical-Current Stimulation|DEVICE: High-Definition Transcranial Alternate-Current Stimulation|DEVICE: High-Definition Personalized Beta-Gamma Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Recombinant Fibroblast Growth Factor-1 for Carpal Tunnel Syndrome
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Sono-guided injection with ES135|PROCEDURE: Sono-guided injection with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Physical Capacities Within the Company and Effect of a Personalized Versus Traditional Training Program on the Quality of Life of Sedentary Employees
Status: COMPLETED
Conditions: Healthy Volunteers|Health
Interventions: OTHER: Performing following WHO (World Health Organization)|OTHER: Performing on their needs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Sotagliflozin|DRUG: Volagidemab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Use of Tourniquet in Total Knee Arthroplasty on the Clinical and Functional Outcomes With 5 Years of Follow up
Status: COMPLETED
Conditions: Use of Tourniquet in Total Knee Arthroplasty
Interventions: PROCEDURE: tourniquet|PROCEDURE: No tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breathing Synchronized PET/CT Scans for the Detection of Malignant Lung & Liver Lesions and Assessment of Tumor Glycolysis
Status: TERMINATED
Conditions: Lung Cancer|Non-small Cell Lung Cancer
Interventions: PROCEDURE: PET/CT and BH PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutonix or Inpact for tHE tReatment Of fEmeropopliteal Stenosis - Drug Coated Balloon
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Lutonix|DEVICE: IN.PACT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bryostatin and Vincristine in B-Cell Malignancies
Status: COMPLETED
Conditions: Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: bryostatin 1|DRUG: vincristine sulfate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Boceprevir in Combination With Peginterferon Alfa-2b Plus Ribavirin for the Treatment of Vietnamese Subjects With Chronic Hepatitis C Genotype 1 (P08599)
Status: WITHDRAWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Boceprevir|DRUG: Peginterferon Alfa-2b 1.5 mcg/kg/week|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Immunogenicity and Safety of GlaxoSmithKline Biologicals' HPV Vaccine in Young Males.
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Cervarix vaccine|BIOLOGICAL: Engerix-B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Pregabalin Vs Duloxetine in Diabetic Peripheral Neuropathic Pain at Variable Dose
Status: UNKNOWN
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Duloxetine Tablets,|DRUG: Pregabalin Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV cps2 Vaccine|BIOLOGICAL: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Avonex (Interferon-beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-remitting MS
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: Interferon-beta-1a (Avonex) plus methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Control Through a Bihormonal Artificial Pancreas in Patients After Total Pancreatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Neoplasms|Type 3c Diabetes|Total Pancreatectomy
Interventions: DEVICE: Bihormonal artificial pancreas (BIHAP) / closed loop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in Follow-up Patients in a Screening Setting
Status: RECRUITING
Conditions: Colonic Adenoma|Adenoma|Polyp of Colon
Interventions: DEVICE: CADe colonoscopy using GI Genius device|DEVICE: White light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of BIA 9-1067 on the Pharmacokinetics of Repaglinide
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Cionni Ring and In-the-bag IOL Implantation for Subluxated Lenses
Status: COMPLETED
Conditions: Lens Subluxation
Interventions: DEVICE: Cionni Modified Capsule Tension Ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BREATHE ALD: A Shared Decision-Making Intervention for Adults With Advanced Lung Disease
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Interstitial
Interventions: OTHER: BRief intervention to Enhance Adherence to Treatment and HEalth advice in Advanced Lung Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Accuracy of Pulsed Fluoroscopy Retrograde Urethrogram Vs the Traditional Retrograde Urethrogram In Diagnosing Urethral Stricture
Status: RECRUITING
Conditions: Urethral Stricture
Interventions: DIAGNOSTIC_TEST: Retrograde Urethrogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Transfusions With Platelets Stored in Platelet Additive Solution II Versus Plasma
Status: COMPLETED
Conditions: Hemato-Oncologic Patients|Myelosuppression|Thrombocytopenia
Interventions: PROCEDURE: platelet transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypoallergenicity of a New Formula in Subjects With Cow's Milk Allergy
Status: COMPLETED
Conditions: Allergy|Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Liquid Extensively hydrolyzed cow's milk protein infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab With Chemoradiotherapy for Women With Locally Advanced Cervical Cancer (CALLA)
Status: COMPLETED
Conditions: Locally Advanced Cervical Cancer
Interventions: BIOLOGICAL: Durvalumab|DRUG: Cisplatin|DRUG: Carboplatin|RADIATION: external beam radiation therapy (EBRT) + brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulizer Versus Dry Powdered Inhalers for Chronic Obstructive Pulmonary Disease (COPD)
Status: TERMINATED
Conditions: COPD|COPD Exacerbation
Interventions: DEVICE: Nebulizers|DEVICE: Dry Powder Inhaler|DRUG: Brovana|DRUG: Pulmicort|DRUG: Atrovent|DRUG: Advair Diskus|DRUG: Spiriva HandiHaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATLANTIS:Extensive Type A Dissections and Thoracic/ Thoraco-Abdominal Aneurysms Repair With LupiAe Hybrid TechNique
Status: WITHDRAWN
Conditions: Aortic Aneurysm
Interventions: PROCEDURE: lupiae technique|PROCEDURE: lupiae technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed Incision Negative Pressure Therapy Versus Standard of Care Surgical Dressing in Revision Total Knee Arthroplasty
Status: COMPLETED
Conditions: Surgical Wound|Revision Total Knee Arthroplasty|Wounds and Injuries|Joint Disease|Musculoskeletal Disease|Prosthesis-Related Infections|Infection|Postoperative Complications|Pathologic Processes
Interventions: DEVICE: Closed Incision Negative Pressure Therapy (ciNPT)|DEVICE: Standard of Care Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research for the Molecular Imaging of the PD-L1 Targeting Tracer
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Lung Cancer
Interventions: OTHER: 18F-WL12 PET or 68Ga-WL12 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Femoral Pediatric Fractures. Walking Spica Cast vs Synthetic Pants
Status: WITHDRAWN
Conditions: Femoral Shaft Fracture|Pediatric ALL
Interventions: DEVICE: Synthetic pants|DEVICE: Spica cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a Ginger and Cardamom Gelatin for Xerostomy in Terminally Ill Patients
Status: COMPLETED
Conditions: Xerostomia|Salivary Gland Diseases|Mouth Diseases
Interventions: DIETARY_SUPPLEMENT: Cardamom, ginger and orange juice gelatin|DIETARY_SUPPLEMENT: Camomile infusion with lemon juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital and Face-to-face Basic Life Support Training for Teacher Candidates
Status: UNKNOWN
Conditions: Cardiopulmonary Resuscitation|Basic Life Support
Interventions: OTHER: Digital Stories and Face-to-face Basic Life Support Trainings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas
Status: RECRUITING
Conditions: Neurofibromatosis Type 2
Interventions: DRUG: REC-2282|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D3 and Prebiotics Supplementation on Cardiovascular Risk Factors in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Vitamin D3|DIETARY_SUPPLEMENT: Prebiotics|DIETARY_SUPPLEMENT: Vitamin D3 placebo|DIETARY_SUPPLEMENT: Prebiotics placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Checkpoint Inhibitor PD-1 Antibody Combined With Chemotherapy in the Perioperative Treatment of Locally Advanced Resectable Gastric or Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Gastric Adenocarcinoma
Interventions: DRUG: PD-1 antibody combined with FOLFIRINOX regimen|DRUG: PD-1 antibody combined with SOX program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Penehyclidine for Prevention of Nausea and Vomiting After Bimaxillary Surgery
Status: COMPLETED
Conditions: Penehyclidine|Postoperative Nausea and Vomiting|Bimaxillar Surgery
Interventions: DRUG: Single injection of penehyclidine|DRUG: Continuous infusion of penehyclidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Irofulven in Treating Patients With Relapsed or Refractory Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: 6-hydroxymethylacylfulvene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Brief Cognitive Behavioural Therapy (CBT) and the Attempted Suicide Short Intervention Program
Status: UNKNOWN
Conditions: Suicide, Attempted
Interventions: BEHAVIORAL: Attempted Suicide Short Intervention Program (ASSIP)|BEHAVIORAL: Cognitive Behavioural Therapy (CBT)|BEHAVIORAL: Suicide Prevention Pathway (SPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: topiramate|DRUG: phentermine|DRUG: topiramate|DRUG: phentermine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Long-Term Safety and Tolerability of Repeated Doses of Degarelix in Prostate Cancer Patients
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Degarelix|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Welcome to WellnessRX: Steps Toward a Healthier Life!
Status: UNKNOWN
Conditions: Life Style|Behavior|Food Habits|Stress|Physical Activity
Interventions: BEHAVIORAL: WellnessRX Lifestyle Change Classes|OTHER: Thrive Market Grocery Credits (4x$25 each)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accuracy of Ultrasound Exam, Including Doppler and Elastography, in the Diagnosis of VOD, Following Bone Marrow Transplantation
Status: UNKNOWN
Conditions: VOD|Ultrasound Therapy; Complications
Interventions: DIAGNOSTIC_TEST: Liver Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurofeedback From the Supplementary Motor Area for Tourette Syndrome
Status: RECRUITING
Conditions: Tourette Syndrome in Adolescence
Interventions: OTHER: Neurofeedback from the SMA|OTHER: Neurofeedback from control region
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IlluminOss Photodynamic Bone Stabilization System for the Treatment of Impending and Actual Pelvis Fractures
Status: RECRUITING
Conditions: Cancer Metastatic|Trauma|Pathologic Fracture
Interventions: DEVICE: IlluminOss pelvic implant for oncologic indication|DEVICE: IlluminOss pelvic implant for geriatric trauma indication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Dose Antenatal Corticosteroids for Late Preterm Delivery
Status: RECRUITING
Conditions: Respiratory Morbidity|Preterm Labor
Interventions: OTHER: we will use reduced dose of acceptable corticosteroids treatment for preterm birth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of PRO-155 Versus Nevanac in Post Phacoemulsification
Status: COMPLETED
Conditions: Cataract|Phacoemulsification Cataract Surgery
Interventions: DRUG: PRO-155|DRUG: Nevanac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair
Status: WITHDRAWN
Conditions: Rotator Cuff Tears
Interventions: DRUG: Testosterone cypionate|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TD-0903 for ALI Associated With COVID-19
Status: COMPLETED
Conditions: Acute Lung Injury (ALI) Associated With COVID-19|Lung Inflammation Associated With COVID-19
Interventions: DRUG: TD-0903|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization (Lifepearls-Irinotecan) in Patients With Colorectal Cancer and Metastatic Disease
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic|Liver Metastasis Colon Cancer
Interventions: DRUG: FOLFOX regimen|BIOLOGICAL: Anti-EGFR or Bevacizumab|DRUG: LIVERPEARLS-Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperinvasive Approach in Cardiac Arrest
Status: TERMINATED
Conditions: Out-of Hospital Cardiac Arrest
Interventions: DEVICE: Prehospital mechanical compressions, intraarrest cooling and in hospital ECLS|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First Time in Humans Study of NST-1024
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: NST-1024|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT