pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparative Effects of Post-exercise Ingestion of a High or Low Molecular Weight Solution on Resistance Exercise Performance
Status: COMPLETED
Conditions: Task Performance and Analysis
Interventions: DIETARY_SUPPLEMENT: Vitargo ®, Swecarb AB, Karlskrona, Sweden|DIETARY_SUPPLEMENT: DE15 maltodextrin, Matrin® M160, Grain Processing Corporation, Muscatine, IA|OTHER: Placebo: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Clinical Study Evaluating the Safety and Efficacy of IDP-115 in Patients With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: IDP-115|DRUG: Vehicle|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APAD2: Effects of Rehabilitation Programme in Adapted Physical Activity (APA) Among Type 2 Diabetics
Status: TERMINATED
Conditions: NIDDM
Interventions: PROCEDURE: Rehabilitation programme in Adapted Physical Activity (APA)|BEHAVIORAL: Therapeutic education primarily focused on dietary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Biomarker Driven Intensified ChemoImmunotherapy With Early CNS Prophylaxis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: COMBINATION_PRODUCT: R-CHOEP|COMBINATION_PRODUCT: DA-EPOCH-R
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COPE for Children With Asthma: Intervention for Children With Asthma
Status: COMPLETED
Conditions: Childhood Asthma|Childhood Anxiety Disorder|Childhood Depression
Interventions: BEHAVIORAL: COPE for Asthma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Video Based Cervical and Thoracal Posture Exercises on Office Workers
Status: COMPLETED
Conditions: Physical Inactivity|Quality of Life
Interventions: OTHER: Posture Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Acceptance-Based Healthy Lifestyle Intervention for Diverse Adolescents
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Acceptance-based Treatment (ABT)|BEHAVIORAL: Health Education (HE) Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Centralized Reminder Recall - Flu RCT2
Status: COMPLETED
Conditions: Influenza, Human|Orthomyxoviridae Infections|RNA Virus Infections|Virus Disease|Respiratory Tract Infections|Respiratory Tract Disease|Vaccines|Physiological Effects of Drugs
Interventions: BEHAVIORAL: R/R - Autodialers|BEHAVIORAL: R/R - Texting|BEHAVIORAL: R/R - mailed postcard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Postpartum Posttraumatic Stress Disorder at Angers University Hospital (ESPT-PP)
Status: UNKNOWN
Conditions: Delivery|Post Partum
Interventions: DIAGNOSTIC_TEST: patient questionnaire and telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Macular Edema Following Cataract Surgery
Interventions: DRUG: Trientine Hydrochloride|OTHER: For Arm B there is no therapeutic intervention other than standard of care, which is cataract surgery.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Pericapsular Nerve Block Versus iv Sedation Analgesia in Reduction of Shoulder Dislocation
Status: RECRUITING
Conditions: Perioperative Pain
Interventions: DRUG: Propofol injection and fentanyl|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Small Acute Cuff Tears, a Randomized Study
Status: UNKNOWN
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Rotator cuff repair|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Feasibility of Rice Bran Supplementation in Children
Status: COMPLETED
Conditions: Dietary Rice Bran Supplementation
Interventions: DIETARY_SUPPLEMENT: Vitamin A|DIETARY_SUPPLEMENT: Rice Bran + Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Insulin Sensitivity in Men With the Metabolic Syndrome
Status: SUSPENDED
Conditions: Metabolic Syndrome
Interventions: PROCEDURE: intravenous glucose tolerance test|DRUG: testosterone|DRUG: anastrozole|DRUG: goserelin acetate implant|PROCEDURE: aerobic capacity (VO2 Max)|PROCEDURE: MRI|PROCEDURE: muscle biopsy|PROCEDURE: measurement of resting metabolic rate (energy expenditure)|PROCEDURE: Dual energy x-ray absorptiometry|PROCEDURE: Fasting oral glucose tolerance test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Short, Animated Storytelling Video to Boost Psychological Capital
Status: NOT_YET_RECRUITING
Conditions: Psychological Capital
Interventions: OTHER: short, animated storytelling video (intervention video)|OTHER: short, animated storytelling attention placebo video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Residual Syntax Score and Syntax Revascularization Index on Outcomes of ACS Patients With Multi-Vessel Disease
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction|Multi Vessel Coronary Artery Disease|NSTEMI - Non-ST Segment Elevation MI|ACS - Acute Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: Residual SYNTAX Score|DIAGNOSTIC_TEST: SYNTAX Revascularization Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke
Status: TERMINATED
Conditions: Prevention of Stroke or Systemic Embolism|Atrial Fibrillation
Interventions: DRUG: Asundexian (BAY2433334)|DRUG: Apixaban|DRUG: Asundexian matching placebo|DRUG: Apixaban matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes|GvHD|Opportunistic Infections|Graft-versus-Host Disease
Interventions: BIOLOGICAL: CD45RA-depleted peripheral blood mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Patients With Stage IV Malignant Melanoma Using PS-341 (Bortezomib, Velcade) and Interferon-alpha-2b in Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Bortezomib|DRUG: Interferon Alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome
Status: NOT_YET_RECRUITING
Conditions: Ehlers-Danlos Syndrome
Interventions: PROCEDURE: skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: MEM 1003|DRUG: MEM 1003|DRUG: Placebo for MEM 1003
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Immunotherapy Plus a Drug in Patients With Progressive Advanced Mucosal Cancer of Different Locations
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Lung Cancer|Vulvar Cancer|Penile Cancer|Cervix Cancer|Head and Neck Squamous Cell Carcinoma|Anal Cancer
Interventions: DRUG: pembrolizumab; vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Insulin Resistance on Branched Chain Amino Acid Metabolism.
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: OTHER: Administration of an 8% crystalline L-amino acid solution with high concentrations of branched chain amino acids.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of Bimatoprost in Japanese Patients With Eyelash Hypotrichosis
Status: COMPLETED
Conditions: Eyelash Hypotrichosis
Interventions: DRUG: bimatoprost solution 0.03%|DRUG: bimatoprost vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Anti-Platelet and Anti-Coagulation Treatment After Lysis of Ischemic Stroke Trial (CATALIST)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Aspirin|DRUG: tinzaparin sodium|DRUG: eptifibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Glucosamine + Chondroitin in Osteoarthrosis
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DIETARY_SUPPLEMENT: EMS Chondroitin Sulfate + Glucosamine Sulfate (Oral powder)|DIETARY_SUPPLEMENT: EMS Chondroitin Sulfate 1200mg + Glucosamine Sulfate 1500mg (hard capsules)|DIETARY_SUPPLEMENT: Zodiac: Chondroitin Sulfate 1200mg + Glucosamine Sulfate 1500mg (Oral powder)|DIETARY_SUPPLEMENT: Zodiac Chondroitin Sulfate 1200mg + Glucosamine Sulfate 1500mg (hard capsules)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Plantarum IS 10560 Supplementation in Women With Functional Constipation
Status: COMPLETED
Conditions: Constipation - Functional
Interventions: DRUG: Lactobacillus plantarum|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Azilsartan medoxomil and chlorthalidone|DRUG: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Efficacies of Sonazoid-CEUS and EOB-MRI in Patients With High Risk of HCC
Status: RECRUITING
Conditions: Hepatocellular Cancer|Liver Cirrhoses|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Diagnostic Sonazoid-CEUS and EOB-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pamiparib (BGB-290) Was Used in EGFR-TkIs Resistant Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|EGF-R Positive Non-Small Cell Lung Cancer
Interventions: DRUG: Parimparib|DRUG: Chemotherapy drug|DRUG: Targeted Therapy Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness and Safety of Synergy XD and Synergy Megatron™ Stent
Status: RECRUITING
Conditions: Coronary Artery Disease|Cardiovascular Diseases|Heart Diseases|Myocardial Ischemia|Coronary Disease
Interventions: DEVICE: Synergy XD stent or Synergy Megatron™ Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Lidocaine Mixed Hyaluronate on Nasolabial Folds Correction
Status: WITHDRAWN
Conditions: Nasolabial Folds Correction|Pain
Interventions: DRUG: Lidocaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Artificial Intelligence-based Speech Enhancement Methods for Hearing Aid Improvement
Status: RECRUITING
Conditions: Deafness Neurosensory
Interventions: OTHER: audiological measurements|OTHER: Objective and subjective audiological measurements|OTHER: Evaluation of the denoising methods REFINED
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur
Status: COMPLETED
Conditions: Anemia|Cardiac Event|Kidney Injury|Fractured Hip
Interventions: BIOLOGICAL: Administration of Red Cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ACP-204 in Adults With Alzheimer's Disease Psychosis
Status: RECRUITING
Conditions: Alzheimer's Disease Psychosis
Interventions: DRUG: ACP-204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Examination for Spleen Volume Evaluation in Myeloproliferative Neoplasms
Status: COMPLETED
Conditions: Myeloproliferative Neoplasm|Polycythemia Vera|Essential Thrombocythemia|Primary Myelofibrosis|Prefibrotic/Early Primary Myelofibrosis
Interventions: DIAGNOSTIC_TEST: ULTRASOUND EXAM AND MRI SCAN
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Targeting HIV Retention and Improved Viral Load Through Engagement ('THRIVE')
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Depression|Anxiety
Interventions: BEHAVIORAL: THRIVE|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Upper Eyelid Retraction Related to Thyroid-associated Ophthalmopathy Using Subconjunctival Triamcinolone Injections
Status: COMPLETED
Conditions: Thyroid-associated Ophthalmopathy
Interventions: DRUG: subconjunctival triamcinolone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myasthenia Gravis Inebilizumab Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: inebilizumab|DRUG: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Dental Pulp Mesenchymal Stem Cells for the Treatment of Chronic Periodontitis Patients
Status: RECRUITING
Conditions: Periodontitis
Interventions: DRUG: Human Dental Fulp Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: I-124-CLR1404
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: (Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Neoplasm Malignant|Carcinoma, Non-Small-Cell Lung|Respiratory Tract Neoplasms|Neoplasms|Neoplasms by Site|Lung Diseases|Respiratory Tract Disease|Carcinoma, Bronchogenic|Bronchial Neoplasms|Adenocarcinoma|Carcinoma|Neoplasms by Histologic Type|EGFR Exon 20 Mutation|EGFR Exon 20 Insertion Mutation|EGFR Activating Mutation|Antineoplastic Agents|Metastatic Lung Cancer|Brain Metastases|EGFR-mutated NSCLC|EGFR Atypical Mutations, Including G719X and L861Q
Interventions: DRUG: BLU-451|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia
Status: COMPLETED
Conditions: Acute Leukemias of Ambiguous Lineage|Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Untreated Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: entinostat|DRUG: clofarabine|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Fatiguability of Tongue Muscles in MS
Status: UNKNOWN
Conditions: Muscle Weakness|Fatigue|Multiple Sclerosis|Deglutition Disorders|Exertion; Excess
Interventions: DEVICE: Iowa Oral Performance Instrument (IOPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy and Adverse Effects of Prapchompoothaweep Remedy and Loratadine for Treatment in AR Patients
Status: COMPLETED
Conditions: Allergic Rhinitis|Adverse Drug Event|Quality of Life
Interventions: DRUG: Prapchompoothaweep remedy|DRUG: Loratadine 10 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-bariatric Hypoglycaemia
Status: COMPLETED
Conditions: Hyperinsulinemic Hypoglycemia|Postprandial Hypoglycemia
Interventions: DRUG: Dasiglucagon|DEVICE: HyoPen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Laser Therapy to Reduce Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Erchonia PL2000 Laser|DEVICE: Placebo laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Non-invasive Vagus Nerve Stimulation for Axial Spondyloarthritis Resistant to Biotherapies
Status: NOT_YET_RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: DEVICE: active stimulation then placebo stimulation|DEVICE: placebo stimulation then active stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Mononuclear Cell (PBMC) Gene Expression in HCV Genotype 1 Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: pegylated interferon alpha 2a and plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Delirium in the (Neuro)Intensive/Critical Care in the Adult and Paediatric Czech Populations
Status: RECRUITING
Conditions: Delirium
Interventions: DIAGNOSTIC_TEST: CAM-ICU|DIAGNOSTIC_TEST: ICDSC|DIAGNOSTIC_TEST: 4AT|DIAGNOSTIC_TEST: p(s)CAM-ICU|DIAGNOSTIC_TEST: CAPD|DIAGNOSTIC_TEST: MASTcz (The Mississippi Aphasia Screening Test)|DIAGNOSTIC_TEST: EEG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mifepristone 10 or 5 mg for 6 Months to Treat Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Mifepristone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Diode Laser Versus Topical Chamomile in Management of Chemotherapy Induced Oral Mucositis
Status: NOT_YET_RECRUITING
Conditions: Chemotherapy Induced Oral Mucositis
Interventions: DEVICE: Low level diode laser|DRUG: Chamomile|DRUG: Ibuprofen analgesic and anti-inflammatory oral gel and miconazole anti fungal oral gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Status: RECRUITING
Conditions: Deafness
Interventions: OTHER: Montreal Cognitive Assessment (MoCA)|OTHER: Detection Threshold Testing|OTHER: Psychophysical Testing|OTHER: Speech Perception Testing|OTHER: Telemetry Recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of the Use of Allogeneic Hematopoietic Stem Cell Transplantation in Reunion Island Patients: Quality of Life, Determinants of Choices and Financial Repercussions
Status: NOT_YET_RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: OTHER: questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Methadone in Pediatric Anesthesiology II
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 0.3mg/kg IV methadone HCl|DRUG: 0.4mg/kg IV methadon HCl|OTHER: control no methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Upper-airway and Breathing Control Therapies for Obstructive Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Oral appliance|DRUG: Oxygen|OTHER: Oral appliance plus oxygen|OTHER: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Degarelix as Second-Line Hormonal Treatment After Prostate-specific Antigen (PSA)-Failure in GnRH Agonist Treated Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: RZ-001 Dose 1|DRUG: RZ-001 Dose 2|DRUG: RZ-001 Dose 3|DRUG: RZ-001 Dose 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of D-serine as add-on Therapy in Recent-onset Psychosis
Status: TERMINATED
Conditions: Psychotic Disorder
Interventions: DIETARY_SUPPLEMENT: D-serine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Breathing Pattern During Neurally Adjusted Ventilatory Assist Ventilation and Pressure Support Ventilation
Status: COMPLETED
Conditions: Respiratory System Abnormalities
Interventions: DEVICE: Servo-i® ventilator, MAQUET,Critical Care, Sweden
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ZYC300 Administered With Cyclophosphamide Pre-Dosing
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Prostate Cancer|Colon Cancer|Renal Cancer
Interventions: DRUG: Cyclophosphamide & ZYC300 (ZYC300 with cyclophosphamide pre-dosing)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: HT-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: FDG-PET|DRUG: Pemetrexed|DRUG: Sirolimus|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic acid tablets|DRUG: Dexamethasone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Ovarian Cancer|Solid Tumors
Interventions: DRUG: Topotecan Liposomes Injection (TLI)|DRUG: Topotecan Liposomes Injection (TLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Hepatic Intra-arterial Injection of Yttrium-90 Microspheres Versus Fluorouracil (5FU) in Colorectal Cancer Metastatic to the Liver Only
Status: COMPLETED
Conditions: Colorectal Neoplasm|Secondary Malignant Neoplasm of Liver
Interventions: DEVICE: SIR Spheres intra-arterial hepatic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential Impact of Clindamycin on Neurosurgery Patients.
Status: COMPLETED
Conditions: Neurologic Complication|Neurosurgery
Interventions: DRUG: Clindamycin 600 mg|DRUG: standard regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trandolapril 4 mg Tablet Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trandolapril 4 mg Tablets|DRUG: Mavik® 4 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasonography of the Patellar Tendon and Achilles Tendon in Children Adolescent and Adults
Status: COMPLETED
Conditions: Obesity, Childhood|Obesity|Tendon Thickening
Interventions: OTHER: Impact of physical activity on tendons
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CARotid plaqUe StabilizatiOn and Regression With Evolocumab.
Status: UNKNOWN
Conditions: Carotid Artery Disease
Interventions: DRUG: Evolocumab|OTHER: lipid-lowering therapy (LLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prostate Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia
Status: UNKNOWN
Conditions: Prostatic Hyperplasia|Benign Prostatic Hyperplasia (BPH)|Prostatism|Lower Urinary Tract Symptoms (LUTS)|Prostatic Hypertrophy|Hyperplasia|Male Urogenital Diseases|Genital Diseases, Male
Interventions: DEVICE: Embozene Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of CPR Teaching in Mass Training
Status: COMPLETED
Conditions: Teaching CPR
Interventions: OTHER: Workshop using Lecture and human model|OTHER: Workshop using Educational Film|OTHER: Workshop using Lecture, human model as well as Educational Film|OTHER: Workshop using Lecture, human model, Educational Film as well as reference book
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Ventilation Distribution in COPD Patients During Breathing Exercises
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Healthy
Interventions: BEHAVIORAL: ELTGOL_Physio|BEHAVIORAL: ELTGOL_Auto|DEVICE: PEP|BEHAVIORAL: 1L-Tidal-Breathing|BEHAVIORAL: Spontaneous Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Yeld of Ultrathin Bronchoscopy in Peripheral Pulmonary Lesions
Status: RECRUITING
Conditions: Lung Cancer|Lung; Node|Lung Diseases|Lung TB|Lung Adenocarcinoma|Lung Transplant Rejection
Interventions: DEVICE: Ultrathin bronchoscopy (MP190F; Olympus Medical Systems, Tokyo, Japan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of a Smartphone Application on Postpartum Weight Loss and Breastfeeding Rates Among Low-income, Urban Women
Status: COMPLETED
Conditions: Breastfeeding
Interventions: OTHER: BreastFeeding Friend (BFF)|OTHER: dummy app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Predicting Response and Toxicity in Patients Receiving Paclitaxel and Avastin for Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Core Biopsy|PROCEDURE: Blood Collection|DRUG: Paclitaxel|DRUG: Avastin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bone Mineral Density Substudy - An Ancillary Study to MTN-003
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine/tenofovir disoproxil fumarate|DRUG: Emtricitabine/tenofovir disoproxil fumarate placebo|DRUG: Tenofovir disoproxil fumarate|DRUG: Tenofovir disoproxil fumarate placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Analgesia to Control Pain in Children Seen in Emergency Department (ED) for a Trauma of a Limb
Status: COMPLETED
Conditions: Trauma
Interventions: DRUG: ibuprofen and codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-US Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease
Status: COMPLETED
Conditions: Advanced Dupuytren's Disease
Interventions: BIOLOGICAL: collagenase clostridium histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transfer Effects of Stationary Bicycle Perturbation Training on Older Adults' Cycling Skills
Status: NOT_YET_RECRUITING
Conditions: Older Adults|Exercise Training|Bicycling
Interventions: OTHER: TSBR|OTHER: PerTSBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Decreased Pump Prime Volume on Blood Transfusions and Postoperative Complications of Patients Undergoing High Risk Cardiac Surgical Procedures
Status: TERMINATED
Conditions: Cardiac Surgery
Interventions: OTHER: Low Prime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Dose Thymoglobulin to Protect Kidney Function After Liver Transplant
Status: COMPLETED
Conditions: Liver Transplantation
Interventions: BIOLOGICAL: Thymoglobulin 3mg total|BIOLOGICAL: Thymoglobulin 4.5mg total|DRUG: Mycophenolate mofetil|DRUG: tacrolimus 3-8|DRUG: tacrolimus 8-12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus
Status: COMPLETED
Conditions: Uremic Pruritus|Pruritus
Interventions: DRUG: nalbuphine HCl ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Recruitment Maneuver With 15 and 30 cmH2O Pressure to Reduce the Postoperative Shoulder Pain
Status: COMPLETED
Conditions: Surgery
Interventions: OTHER: Pulmonary recruitment maneuver (PRM)- 30 cm H2O|OTHER: Pulmonary recruitment maneuver (PRM)- 15 cm H2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Medical Home-Based Intervention to Prevent Child Neglect in High-Risk Families
Status: COMPLETED
Conditions: Child Abuse
Interventions: BEHAVIORAL: Child Abuse Prevention Problem Solving|BEHAVIORAL: Active Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Zotepine Versus Risperidone in Aggressive Schizophrenic Patients of Acute Ward
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Zotepine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Centre Nocturnal Hemodialysis (INHD): A Long-Term Follow-Up Study
Status: COMPLETED
Conditions: End-stage Renal Disease|Left Ventricular Hypertrophy
Interventions: PROCEDURE: Conventional Hemodialysis|PROCEDURE: In-centre Nocturnal Hemodialysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nursing Intervention in Supporting Family Caregivers of Patients Undergoing Stem Cell Transplant
Status: WITHDRAWN
Conditions: Anxiety Disorder|Depression|Fatigue
Interventions: OTHER: educational intervention|OTHER: psychosocial support for caregiver|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of HCV Genotype 1 Patients in the UK Treated With ViraferonPeg and Rebetol (Study P05269)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2b (SCH 54031)|DRUG: Ribavirin (SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iribrine Plus Tucidinostat in the Treatment of HR+/HER2 Advanced Breast Cancer After CDK4/6 Inhibitor Failure
Status: RECRUITING
Conditions: HR Positive HER2 Negative Advanced Breast Cancer
Interventions: DRUG: Eribulin and Tucidinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can a Novel Telemedicine Tool Reduce Disparities Related to the Identification of Preschool Children With Autism?
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Tele-assessment + In-person assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Disease Modifying Therapies Withdrawal in Inactive Secondary Progressive Multiple Sclerosis Patients Older Than 50 Years (STOP-I-SEP)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: DMT withdrawal|DRUG: DMT continuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions
Status: UNKNOWN
Conditions: Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel
Interventions: DRUG: Intrauterine injection of hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioural Therapy (CBT) and Recreational Activity for Autism Spectrum Disorders (ASD)
Status: COMPLETED
Conditions: Asperger Syndrome|Autistic Disorder|Atypical Autism
Interventions: BEHAVIORAL: Cognitive behaviour therapy|BEHAVIORAL: Recreational activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodialysis Eating Education Intervention in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: BEHAVIORAL: Hemodialysis eating index (HDEI) base education intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity
Status: UNKNOWN
Conditions: Dry Eye
Interventions: DRUG: FreshKote|DRUG: Systane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine With Epinephrine vs. Bupivacaine With Epinephrine as Local Anesthetic Agents in Wide-awake Hand Surgery
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Wrist block anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics and Pharmacokinetics of 3 New Developed Coated Glucose Beads in 20 Obese Healthy Subjects
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DRUG: coated beads glucose (8 g) and caffeine anhydrous|DRUG: coated beads glucose (8 g) and caffeine anhydrous|DRUG: coated beads glucose (8 g) and caffeine anhydrous|DRUG: coated beads glucose (8 g)|DRUG: uncoated beads glucose (8 g) and caffeine anhydrous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fluid Loading in Abdominal Surgery: Saline Versus Hydroxyethyl Starch (FLASH Study)
Status: COMPLETED
Conditions: Postoperative Morbidity|Postoperative Mortality
Interventions: DRUG: Hydroxethyl starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy (SBRT) With Concurrent Boost for Low- and Intermediate-Risk Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: Prostate SBRT with concurrent boost to intraprostatic lesion(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: PF-04937319 10 mg|DRUG: PF-04937319 50 mg|DRUG: PF-04937319 100 mg|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Futuximab/modotuximab|DRUG: Trifluridine/Tipiracil|DRUG: Trifluridine/Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rhGAA in Patients With Infantile-onset Glycogen Storage Disease-II (Pompe Disease)
Status: COMPLETED
Conditions: Glycogen Storage Disease Type II|Pompe Disease|Acid Maltase Deficiency Disease|Glycogenosis 2
Interventions: BIOLOGICAL: Myozyme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)
Status: COMPLETED
Conditions: Atrial Fibrillation|Vascular Risk
Interventions: DRUG: clopidogrel (SR25990C)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Endodontic Status on Periodontal Healing of Concomitant Endodontic Periodontal Lesions
Status: COMPLETED
Conditions: Periodontal Pocket
Interventions: PROCEDURE: Scaling and root planing|OTHER: Endodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Absorption Characteristics of Two Multivitamin Mineral Formulations (Gel vs. Tablet/Capsule)
Status: UNKNOWN
Conditions: Vitamin Deficiency
Interventions: DIETARY_SUPPLEMENT: Multivitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome
Status: TERMINATED
Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome|Prostatitis
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anatomical and Functional Outcomes of Perigee and Apogee Mesh in Total Pelvic Floor Reconstruction Versus Gynecare Prolift
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: DEVICE: Perigee and Apogee Mesh|DEVICE: Gynecare Prolift Mesh|PROCEDURE: Traditional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Duloxetine and Neurofeedback Training for the Treatment of Chemotherapy Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Chemotherapy-Induced Peripheral Neuropathy|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: DRUG: Duloxetine|BEHAVIORAL: Neurofeedback|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Trabodenoson in Adults With Ocular Hypertension or Primary Open-angle Glaucoma
Status: COMPLETED
Conditions: Primary Open-Angle Glaucoma (POAG)|Ocular Hypertension (OHT)
Interventions: DRUG: trabodenoson 4.5% BID|DRUG: trabodenoson 6.0% QD|DRUG: trabodenoson 3.0% QD|DRUG: timolol 0.5% BID|DRUG: placebo BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Effectiveness of the Biosensors Microcatheter in Coronary Chronic Total Occlusions (CTO) - BIOMICS
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DEVICE: Microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Stage IA Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer
Interventions: DRUG: Azacitidine|DRUG: Entinostat|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Hypertonic Dextrose Spray as Endoscopic Topical Hemostatic Agent for Acute Non-Variceal Upper GI Bleeding
Status: UNKNOWN
Conditions: Gastro Intestinal Bleeding
Interventions: DRUG: Dextrose 40 % in Water|DRUG: Adrenaline 1 Mg/mL Solution for Injection|PROCEDURE: argon plasma coagulation|PROCEDURE: Hemoclip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT