pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Single Limb Resistance Training in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Control group|BEHAVIORAL: High-repetitive single limb training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus as Primary Therapy for the Treatment of Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease|Blood and Marrow Transplant (BMT)
Interventions: PROCEDURE: high dose chemotherapy and autologous hematopoietic cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Validity of the PAP Problems Triage Tool in Patients With PAP Treatment for Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: OTHER: TT|OTHER: VE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HMPL-523 CYP3A/P-gp Inhibitor and CYP Inducer Study
Status: COMPLETED
Conditions: Relapsed or Refractory Lymphoma
Interventions: DRUG: HMPL-523|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Uterine Artery Occlusion for Fibroid Related Bleeding
Status: TERMINATED
Conditions: Menorrhagia|Uterine Fibroids
Interventions: DEVICE: Doppler-Guided Uterine Artery Occlusion Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transnasal Therapy for Acute Migraine Attack
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: OTHER: Humidified oxygen|OTHER: Dry oxygen|OTHER: Humidified air|OTHER: Dry air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC
Status: SUSPENDED
Conditions: Prostate Cancer
Interventions: DRUG: 225Ac-J591|DIAGNOSTIC_TEST: 68Ga-PSMA-HBED-CC injection|DRUG: 225Ac-J591
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescent Visualization in Early Oral Cancer
Status: COMPLETED
Conditions: Oral Squamous Cell Carcinoma or Severe Dysplasia
Interventions: PROCEDURE: resection of oral cancer|PROCEDURE: resection of oral cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis
Status: COMPLETED
Conditions: Hypersensitivity Pneumonitis|Chronic Hypersensitivity Pneumonitis|Interstitial Lung Disease|Extrinsic Allergic Alveolitis|Health-related Quality of Life
Interventions: OTHER: Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MitoQ and Exercise Effects on Vascular Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging|Menopause
Interventions: DIETARY_SUPPLEMENT: MitoQ|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Combined Weekly Bortezomib and Tositumomab I-131 in Patients With Relapsed or Refractory Follicular Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma
Interventions: DRUG: Bortezomib and Tositumomab I-131
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Positive End Maximum Voluntary Ventilation and Dyspnea Index in Patients After Valvular Heart Surgery
Status: COMPLETED
Conditions: Respiration Disorders
Interventions: OTHER: respiratory exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thermocoagulation for Treatment of Precancerous Cervical Lesions
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|HPV Infection|CIN 2/3
Interventions: DEVICE: Thermocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized SAD and MAD Study Evaluating the Safety and Tolerability of RPh201 in Healthy Subjects and in Adults With Alzheimer's Disease
Status: COMPLETED
Conditions: Healthy Volunteers|Moderate to Severe Alzheimer Patients
Interventions: DRUG: RPh201, botanical drug product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Topotecan in Treating Patients With Newly Diagnosed Localized Ewing's Sarcoma
Status: WITHDRAWN
Conditions: Sarcoma
Interventions: DRUG: cyclophosphamide|DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|PROCEDURE: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Daytime Cyclic Enteral Nutrition Versus Standard Continuous Enteral Nutrition in the Intensive Care Unit: a Pilot Randomized Controlled Trial
Status: RECRUITING
Conditions: Enteral Nutrition
Interventions: OTHER: day time cyclic nutrition|OTHER: continuous nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: TQB2450 Injection Combined With Chemotherapy Followed by Sequential Combination With Anlotinib Hydrochloride Capsule for First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer.
Status: NOT_YET_RECRUITING
Conditions: Advanced Squamous Non-Small Cell Lung Carcinoma
Interventions: DRUG: TQB2450|DRUG: Anlotinib hydrochloride capsule|DRUG: Tislelizumab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Lymphoma, Follicular|Lymphoma, Large B-Cell, Diffuse|Carcinoma, Non-Small-Cell Lung|Carcinoma, Renal Cell|Carcinoma, Squamous Cell of Head and Neck|Malignant Melanoma
Interventions: DRUG: PF-05082566|DRUG: rituximab|DRUG: PF-05082566
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative mFOLFOX Plus Pembrolizumab in Gastroesophageal Junction (GEJ) and Stomach Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastro Esophageal Junction Cancer|Stomach Cancer|Adenocarcinoma
Interventions: DRUG: Neoadjuvant Treatment - mFOLFOX6 & Pembrolizumab|DRUG: Adjuvant Treatment - mFOLFOX & Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of Exenatide Once-Weekly Injection on Glucose Control and Safety in Asian Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide once weekly|DRUG: exenatide twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Xerostomia for Nasopharyngeal Carcinoma Patients Treated With or Without Superficial Parotid Lobe-sparing Intensity-modulated Radiotherapy
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma|Radiation-induced Xerostomia
Interventions: RADIATION: superficial parotid lobe-sparing intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of the TDT for Prevention of Anastomotic Leakage After Laparoscopic Anterior Resection for Rectal Cancer
Status: COMPLETED
Conditions: Anastomotic Leakage|Rectal Neoplasms
Interventions: PROCEDURE: with TDT|PROCEDURE: without TDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Cyclophosphamide and Outpatient IV Interleukin-2 in Metastatic Melanoma
Status: WITHDRAWN
Conditions: Metastatic Melanoma
Interventions: DRUG: Cyclophosphamide and Interleukin 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Use in Hospitalized Patients With COVID-19: Impact on Progression to Severe or Critical Disease
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Antioxidant Docosahexaenoic Acid (DHA) in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis in Children
Interventions: DIETARY_SUPPLEMENT: ANTIOXIDANT DHA TRIGLYCERIDE (TRIDOCOSAHEXAENOINE-AOX®)|DIETARY_SUPPLEMENT: PLACEBO (OLIVE OIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Efficacy and Safety of Povorcitinib in Adults With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Urticaria|Chronic Spontaneous Urticaria|Chronic Idiopathic Urticaria|Hives|Angioedema|Pruritis
Interventions: DRUG: Povorcitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Assessment Protocol for the Upper Limb for Pediatric Age
Status: RECRUITING
Conditions: Upper Extremity|Child|Range of Motion, Articular
Interventions: DEVICE: Upper limb Kinematic Assessment with Optoelectronic system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zoledronic Acid|DRUG: Androgen Deprivation Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Plus: Improving Infant Growth Through Diet and Enteric Health
Status: COMPLETED
Conditions: Stunting|Malnutrition; Protein|Enteric Pathogens|Campylobacter Infections
Interventions: DRUG: Azithromycin Oral Product|DRUG: Placebos|DIETARY_SUPPLEMENT: Protein Supplement|DIETARY_SUPPLEMENT: Isocaloric Supplement|DIETARY_SUPPLEMENT: Egg|BEHAVIORAL: Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation Of Weight Loss And Body Composition Changes After Dosing With Either Placebo Or One Of Two Active Drugs
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Obesity
Interventions: DRUG: GW869682|DRUG: GSK189075|DRUG: GSK189075-Placebo|DRUG: GW869682-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Alisertib, Abiraterone Acetate and Prednisone in Treating Patients With Hormone-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: Alisertib|DRUG: Abiraterone acetate|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS)
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: BIOLOGICAL: daxibotulinumtoxinA for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of LB-100 With Docetaxel in Solid Tumors
Status: COMPLETED
Conditions: Tumors|Neoplasms|Cancer
Interventions: DRUG: LB-100 for Injection|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Web- Versus Classroom-based Basic Ultrasound and Extended Focused Assessment With Sonography for Trauma (EFAST) Training in Two European Hospitals
Status: COMPLETED
Conditions: Learning
Interventions: OTHER: Didactic training in basic ultrasound and the EFAST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study to Learn More About the Safety and Effectiveness of Rivaroxaban (Xarelto) When Given Together With Acetylsalicylic Acid to Indian People With Narrowing of the Arteries of the Heart (CAD) and/or With Reduced Blood Flow in the Arteries of the Legs and Arms With Symptoms (Symptomatic PAD)
Status: COMPLETED
Conditions: Prevention of Atherothrombotic Events|Coronary Artery Disease (CAD)|Symptomatic Peripheral Artery Disease (Symptomatic PAD)
Interventions: DRUG: Rivaroxaban (Xarelto,Bay 59-7939)|DRUG: Acetylsalicylic acid(ASA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MR Lymphatic Imaging in Idiopathic Intracranial Hypertention
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Intracranial Hypertension
Interventions: DIAGNOSTIC_TEST: 3T MRI with Gadobutrol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cerebral Perfusion Pressure Using Precedex and Other Sedatives
Status: COMPLETED
Conditions: Endotracheal Intubation|Continuous IV Sedation|ICP Monitoring
Interventions: DRUG: Standard-of-Care plus Dexmedetomidine|OTHER: Standard-of-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Transfer of a Vulnerable Atherosclerotic Plaque Tracer : 99mTc-cAbVCAM1-5 (ATHENA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Atherosclerosis
Interventions: DRUG: 99mTccAbVCAM1-5 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of the Effect of LANAP as an Adjunct Treatment in Management of Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Laser
Interventions: RADIATION: LANAP (Laser Assisted New Attachment Procedure)|RADIATION: LANAP off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Novel Treatment Combinations in Patients With Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer|Advanced or Metastatic Non-Small-Cell Lung Cancer|Resectable Non-Small-Cell Lung Cancer
Interventions: DRUG: Zimberelimab (ZIM)|DRUG: Domvanalimab (DOM)|DRUG: Sacituzumab govitecan-hziy (SG)|DRUG: Etrumadenant (ETRUMA)|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Docetaxel|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of STI-5656 (Abivertinib Maleate) in Subjects Hospitalized Due to COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: STI-5656|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azelnidipine Anti-Coronary Atherosclerotic Trial in Hypertensive Patients by Serial Volumetric IVUS Analysis(ALPS-J)
Status: COMPLETED
Conditions: Hypertension|Coronary Atherosclerosis
Interventions: DRUG: Calcium channel blockers (amlodipine, azelnidipine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Offering Proactive Tobacco Treatment
Status: COMPLETED
Conditions: Tobacco Use Cessation
Interventions: OTHER: proactive outreach (PRO)|OTHER: telephone counseling (TC)|OTHER: Nicotine replacement therapy (NRT)|OTHER: Usual care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of the Efficacy, Safety and Tolerability of BYM338 (Bimagrumab) in Patients With Sporadic Inclusion Body Myositis Who Previously Participated in the Core Study CBYM338B2203
Status: COMPLETED
Conditions: Sporadic Inclusion Body Myositis
Interventions: DRUG: Bimagrumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemostasis and Inflammation in COVID-19 Patients With Venous and Arterial Thrombotic Complications
Status: COMPLETED
Conditions: Venous Thromboembolism|covid19|Thrombosis
Interventions: OTHER: standard of care anticoagulation in absence of thrombotic complications|OTHER: standard of care anticoagulation in presence of thrombotic complications|OTHER: standard of care anticoagulation in combination with elastic compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Study the Effect of Magnetic Activated Sperm Sorting on the Outcome of in Vitro Fertilization-embryo Transplantation
Status: UNKNOWN
Conditions: Infertility, Male
Interventions: PROCEDURE: Magnetic activated sperm sorting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DRUG: Argatroban|DRUG: unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Intravenous Infusion Study of rHIgM22 in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: rHIgM22
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: BMS-986315|BIOLOGICAL: nivolumab|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Safety, PK, and Efficacy of Tafasitamab and Parsaclisib in Participants With Relapsed/Refractory Non Hodgkin Lymphoma (R/R NHL) or Chronic Lymphocytic Leukemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Non Hodgkin Lymphoma
Interventions: DRUG: tafasitamab|DRUG: parsaclisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Vaccine in HIV-uninfected Adults
Status: RECRUITING
Conditions: HIV
Interventions: BIOLOGICAL: IHV01|BIOLOGICAL: A244|BIOLOGICAL: ALFQ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of GLPG1205 in Healthy Japanese and Caucasian Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1205|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AIR-program and HUS Internet Therapy Compared to Treatment as Usual in Functional Disorders and Post Covid-19 Condition
Status: RECRUITING
Conditions: Functional Disorders|Post Covid-19
Interventions: BEHAVIORAL: AIR-program|BEHAVIORAL: HUS Internet therapy|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omalizumab Before Onset of Exacerbations
Status: RECRUITING
Conditions: Asthma in Children|Atopy|Viral Upper Respiratory Infection
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Adaptive Clinical Trial of Antivirals for COVID-19 Infection
Status: UNKNOWN
Conditions: COVID
Interventions: DRUG: Favipiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of Cenicriviroc and Pioglitazone, When Dosed Alone or in Combination
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cenicriviroc|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Phase II Trial of Osimertinib With or Without SRS for EGFR Mutated NSCLC With Brain Metastases
Status: COMPLETED
Conditions: Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Osimertinib|RADIATION: Stereotactic Radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DAC Combined With HAAG Regimen in Newly Diagnosed Younger AML Patients
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia|Induction Chemotherapy
Interventions: DRUG: Decitabine plus HAAG regimen|DRUG: Idarubicine plus Cytarabine regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of New Pretreatment Method in Transnasal Endoscopy
Status: COMPLETED
Conditions: Pretreatment Method of Transnasal Endoscopy
Interventions: PROCEDURE: pretreatment method for transnasal endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Itraconazole|DRUG: Flucytosine|DRUG: Fluconazole|DRUG: Amphotericin B|DRUG: Interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Laryngoscope Blades for Orotracheal Intubation in the Operating Room
Status: COMPLETED
Conditions: Intubation
Interventions: DEVICE: metallic single use blade|DEVICE: plastic single use blade|DEVICE: metallic reusable blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Cannabidiol as a Treatment for AUD Comorbid With PTSD
Status: COMPLETED
Conditions: Alcohol Use Disorder|Post Traumatic Stress Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Validation Process for Confirmation of the French Version of the Pediatric Quality of Life Inventory :PedsQLTM.
Status: UNKNOWN
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: Duchenne Muscular Dystrophy of the PedsQL ™ 3.0 scale|OTHER: The following data of motor function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Antimicrobial-Prescribing in Emergency Departments
Status: COMPLETED
Conditions: Anti-Bacterial Agents|Respiratory Tract Infections
Interventions: BEHAVIORAL: Audit-and-feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Donafenib Combine With Sintilimab and HAIC in Neoadjuvant of Resectable Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Donafenib|DRUG: Sintilimab|OTHER: HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Different Doses of ExPEC4V (JNJ-63871860) in Healthy Japanese Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ExPEC4V|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Superficial Cervical Plexus Block for Pacemaker Insertion
Status: TERMINATED
Conditions: Pacemaker Insertion|Regional Block|Pain
Interventions: PROCEDURE: Superficial Cervical Plexus Block (SCP) block|PROCEDURE: Local site infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ramelteon for Insomnia Comorbid With Asthma
Status: TERMINATED
Conditions: Insomnia|Asthma
Interventions: DRUG: Ramelteon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)
Status: RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Zoledronate or Alendronate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study of Sintilimab in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: sintilimab (after the change)|DRUG: sintilimab (before the change)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Post-licensure Safety Study of IMOJEV® in Thailand
Status: COMPLETED
Conditions: Japanese Encephalitis
Interventions: BIOLOGICAL: IMOJEV®: Live attenuated Japanese encephalitis chimeric virus vaccine|BIOLOGICAL: IMOJEV®: Live attenuated Japanese encephalitis chimeric virus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Isatuximab SAR650984|DRUG: Cemiplimab REGN2810
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation and Application of a Multi-dimentional Frailty Assessment Tool-Cohort Intervention and Follow up
Status: RECRUITING
Conditions: Frailty|Fall|Sarcopenia
Interventions: BEHAVIORAL: Multidomain frailty prevention method|OTHER: Regular follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Maintenance Treatment of Healed Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: TAK-438|DRUG: TAK-438|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Simplify® Cervical Artificial Disc
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disease
Interventions: DEVICE: Simplify Disc|DEVICE: Anterior Cervical Discectomy & Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suppression of Oral HHV8 Shedding With Valganciclovir
Status: COMPLETED
Conditions: Human Herpesvirus 8
Interventions: DRUG: valganciclovir|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Addition of Structured Lipids in Starter Formulas
Status: COMPLETED
Conditions: Healthy Newborn Infants
Interventions: OTHER: Whey predominant starter formula|OTHER: Whey predominant starter formula + 40% palmitic acid|OTHER: Whey predominant starter formula + 50% palmitic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cyclosporine A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Change in Brain Bioenergetics in Bipolar Disorder in Response to Photic Stimulation
Status: WITHDRAWN
Conditions: Bipolar Disorder|Schizophrenia|Healthy Controls
Interventions: DEVICE: Magnetic resonance spectroscopy (MRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Human Autologous Lung Stem Cell Transplant for Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis and Progressive Fibrotic Interstitial Lung Disease
Interventions: BIOLOGICAL: Lung Spheroid Stem Cells 100 million|BIOLOGICAL: Lung Spheroid Stem Cells 200 million
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Adipose Derived Mesenchymal Stem Cells on Sexual Hormone Deficiency
Status: COMPLETED
Conditions: Hormone Deficiency
Interventions: COMBINATION_PRODUCT: adipose-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of iNO in Patients With Submassive and Massive PE
Status: WITHDRAWN
Conditions: Pulmonary Embolism|Pulmonary Embolism Subacute Massive
Interventions: DRUG: inhaled nitric oxide (iNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of HPV (Human Papilloma Virus) Vaccine in Healthy Females 9 to 15 Years of Age in India (V501-029)
Status: COMPLETED
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of AK119 and AK 112 With or Without Chemotherapy for Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: AK119|DRUG: AK112|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Calcium folinate|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
Status: COMPLETED
Conditions: Schizoaffective Disorder|Schizophrenia|Bipolar Disorder|Major Depressive Disorder
Interventions: OTHER: Mobile Interventionist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training in Survivors of Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Physical Exercise|Cardiotoxicity|Cardiovascular Diseases|Chemotherapeutic Toxicity
Interventions: BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Combined Aerobic and Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bacillus Calmette-guérin Vaccination to Prevent COVID-19
Status: COMPLETED
Conditions: COVID-19|Virus Diseases|Corona Virus Infection|Coronary Heart Disease|Chronic Obstructive Pulmonary Disease
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Palonosetron With Granisetron as a Control in Patients Receiving Highly Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: palonosetron|DRUG: granisetron hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Salvage of Infected Cardiovascular Implantable Electronic Devices (CIED) by Localized High-dose Antibiotics
Status: UNKNOWN
Conditions: Infection
Interventions: DRUG: CITA-RNPT|PROCEDURE: Extraction of infected CIED
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers
Status: UNKNOWN
Conditions: Alcohol Abuse|Alcohol Dependence|Cannabis Abuse|Cannabis Dependence|Other Substance Abuse
Interventions: BEHAVIORAL: Adolescent group therapy|BEHAVIORAL: Transitional family therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Assessment of Robotic Sacrocolpopexy: a European Multicentric Cohort (PARSEC)
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Robotic assisted sacrocolpopexy (RASC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fluocinonide Cream 0.1% (Vanos(R)) in Reducing Itch in Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Fluocinonide cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Use of High-flow Oxygen Nasal Cannula in End-of-life Lung Disease Patients
Status: WITHDRAWN
Conditions: Lung Disease|Acute Respiratory Distress Syndrome
Interventions: DEVICE: HFONC|DEVICE: Conventional oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrophysiological Study of Interindividual Differences in Speech-understanding Among Cochlear Implant Patients
Status: UNKNOWN
Conditions: Hearing Loss
Interventions: OTHER: Electrophysiological study of the interindividual variability of vocal performance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pomalidomide in Treating Patients With Relapsed or Refractory Waldenstrom Macroglobulinemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Waldenstrom Macroglobulinemia|Refractory Waldenstrom Macroglobulinemia
Interventions: DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: HKI-272|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery
Status: COMPLETED
Conditions: Pain|Perioperative/Postoperative Complications
Interventions: PROCEDURE: wound care management|PROCEDURE: wound care management|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia
Status: COMPLETED
Conditions: Diabetes Mellitus|Critical Limb Ischemia|Critical Lower Limb Ischemia|Diabetic Foot
Interventions: OTHER: data and specimen collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer Stage III
Interventions: DRUG: Neoadjuvant chemoradiotherapy based on irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Navarixin (SCH 527123) in Participants With Allergen-Induced Asthma (P05363)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Navarixin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OD-doxy-PNV-COVID-19 Old Drug " DOXY " for Prevention of New Virus " COVID-19 "
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Doxycyclin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vemurafenib and Cobimetinib in Treating Patients With BRAF V600E Mutation Positive Craniopharyngioma
Status: ACTIVE_NOT_RECRUITING
Conditions: BRAF V600E Mutation Present|Papillary Craniopharyngioma
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Lidocaine for Perioperative and Postoperative Analgesia
Status: UNKNOWN
Conditions: Analgesic Drug Dependence
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Lidocaine Hydrochloride and Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ferric Carboxymaltose (Ferinject®) With or Without Erythropoietin in Patients Undergoing Orthopaedic Surgery
Status: TERMINATED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferinject ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E or Lipoic Acid on Serum Oxyphytosterol Concentrations
Status: UNKNOWN
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Lipoic acid|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Bilateral Erector Spinae Plane Block in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Ultrasound guided erector spinae plane block|OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Green Tea Extract on Type 2 Diabetes With Hyperlipidemia
Status: COMPLETED
Conditions: Type 2 Diabetes|Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Green tea extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Mild Hypothermia on Reversal of Rocuronium With Sugammadex
Status: COMPLETED
Conditions: Underdosing of Other General Anesthetics
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plant Sterol INtervention for Cancer Prevention (PINC)
Status: UNKNOWN
Conditions: Hypercholesterolemia|Breast Cancer|Obesity
Interventions: DIETARY_SUPPLEMENT: Cholesterol Reducing Strawberry Yogurt Drink (Tesco Ltd)|DIETARY_SUPPLEMENT: Low Fat Strawberry Yogurt Drinks (Morrisons Ltd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiopulmonary Resuscitation by Children
Status: COMPLETED
Conditions: Cardiopulmonary Arrest With Successful Resuscitation
Interventions: BEHAVIORAL: Training on emergency telephone numbers and mnemonics|BEHAVIORAL: Sham generic formation on the cardiopulmonary arrest.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dynamic Locking Screws 5.0 vs. Standard Locking Screws in Fracture of Distal Femur Treated With Locked Plate Fixation
Status: TERMINATED
Conditions: Distal Femur Fractures
Interventions: DEVICE: DLS 5.0 (Dynamic locking screws)|DEVICE: SLS (Standard locking screw)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Esophageal Squamous Cell Carcinoma|Sintilimab|Radiotherapy|Concurrent Chemoradiotherapy|Immunonutrition
Interventions: RADIATION: Radiotherapy|DRUG: Programmed Cell Death Protein 1 Inhibitor|DIETARY_SUPPLEMENT: Immunonutrition support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Vitamin D Deficiency in Very Low Birth Weight Infant (VLBW) Infants Part 2
Status: COMPLETED
Conditions: Infant, Very Low Birth Weight|Calcium Deficiency|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 400 IU Cholecalciferol- Vitamin D Daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Training and Calibration of Dental Examiners
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DRUG: Fluoride|DRUG: Triclosan|DRUG: Chlorhexidine gluconate|DRUG: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Darifenacin 7.5 MG Extended Release Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Kinesiotaping on paın, Function and electrophysiologıcal Findings in Patient With Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: I tape technique|OTHER: Button hole technique|OTHER: exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S-1 Concurrent With Radiotherapy Versus Radiotherapy for Elderly Patients With Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Chemoradiation
Interventions: RADIATION: Radiotherapy 54 Gy|RADIATION: Radiotherapy 60 Gy|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of EUR-1008 (APT-1008) Pancreatic Enzyme Product in Participants With Cystic Fibrosis and Exocrine Pancreatic Insufficiency
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency
Interventions: DRUG: EUR-1008 (APT-1008)|DRUG: Placebo|DRUG: Placebo|DRUG: EUR-1008 (APT-1008)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT