pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: IMO-2125|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Changing to DuoTrav From Prior Therapy
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Travoprost 0.004%/Timolol 0.5% Fixed Combination eye drops solution (Duotrav®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: PMI-150 (intranasal ketamine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Exercise Training on Left Ventricular Function in Type 2 Diabetic Patients Post Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent|Coronary Arteriosclerosis|Post Coronary Artery Bypass Grafting
Interventions: BEHAVIORAL: Exercise training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy of Disci/Rhus Toxicodendron Comp.®, in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Disci/Rhus toxicodendron comp.®|DRUG: placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment Method for the Relief of Symptoms of Dry Eye
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye|Dry Eye Syndromes
Interventions: DEVICE: Walther System|DEVICE: Sham Walther System|DRUG: Non preserved ocular lubricants|PROCEDURE: Eye lid procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing Help-Seeking in Military Service Members
Status: COMPLETED
Conditions: Military Service Members at Elevated Suicide Risk
Interventions: BEHAVIORAL: Cognitive Bias Modification Intervention for Help-Seeking Stigma|BEHAVIORAL: Placebo Cognitive Bias Modification (CBM-Placebo)|BEHAVIORAL: Self-Directed Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multicenter Open Clinical Study of Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of BAT 8010 for Injection Combined With BAT 1006 in the Treatment of Locally Advanced or Metastatic Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BAT8010 for Injection|DRUG: BAT1006 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative PK PD Study in PAH Patients (Fox vs. I-Neb)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: lloprost(Ventavis,BAYQ6252, 20 µg/mL)|DRUG: lloprost(Ventavis,BAYQ6252, 10 µg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Co-Administration of Betahistine as Adjunctive to Olanzapine in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Betahistine standard formulation|DRUG: Betahistine Extended Release formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of Nature-based Exposure on the Immune System and Skin Health of Atopic Dermatitis Patients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: OTHER: Nature-based exposure by biodiversity component in lotion.|OTHER: Placebo group using colored lotion.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Manganese Chloride|DRUG: nab-paclitaxel|DRUG: Platinum chemotherapy|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topiramate Treatment of Alcohol Use Disorders in Veterans With Post Traumatic Stress Disorder (PTSD): A Pilot Controlled Trial of Augmentation Therapy
Status: COMPLETED
Conditions: PTSD|Alcohol Abuse|Alcoholism
Interventions: DRUG: Topiramate|OTHER: Placebo administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect of Allogeneic Meniscus Transplantation
Status: COMPLETED
Conditions: Meniscus Lesion
Interventions: PROCEDURE: Meniscus Allograft Transplantation|PROCEDURE: Meniscectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Progesterone vs Placebo Therapy for Women With Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: BIOLOGICAL: Progesterone Lozenges|OTHER: Matched Placebo Lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Purine Analog-Based Conditioning in Patients With Severe Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Antithymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elvitegravir (EVG) Cerebrospinal Fluid (CSF) Pharmacokinetics in HIV-Infected Individuals
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Stribild|DRUG: Genvoya
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Eplerenone in Elderly Hypertensive Early Stage Chronic Kidney Disease (CKD) Patients
Status: WITHDRAWN
Conditions: Hypertension|Chronic Kidney Disease.
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of Endometrial Ultrasound to Predict Implantation
Status: UNKNOWN
Conditions: Infertility, Subfertility
Interventions: DIAGNOSTIC_TEST: Endometrial Pattern on Ultrasound at ET|DIAGNOSTIC_TEST: Endometrial Pattern on Ultrasound at HCG|DIAGNOSTIC_TEST: Endometrial Pattern on Ultrasound at TVOR|DIAGNOSTIC_TEST: Endometrial Pattern on Ultrasound at co-ordination scan|DIAGNOSTIC_TEST: Endometrial thickness at HCG|DIAGNOSTIC_TEST: Endometrial thickness at TVOR|DIAGNOSTIC_TEST: Endometrial thickness at ET|DIAGNOSTIC_TEST: Endometrial thickness at coordination scan|DIAGNOSTIC_TEST: Endometrial volume at HCG|DIAGNOSTIC_TEST: Endometrial volume at TVOR|DIAGNOSTIC_TEST: Endometrial volume at ET|DIAGNOSTIC_TEST: Endometrial volume at coordination scan|DIAGNOSTIC_TEST: Blood test for progesterone at HCG|DIAGNOSTIC_TEST: Blood test for progesterone at TVOR|DIAGNOSTIC_TEST: Blood test for progesterone at ET|DIAGNOSTIC_TEST: Blood test for progesterone at coordination scan|DIAGNOSTIC_TEST: Change in endometrial pattern between TVOR and ET|DIAGNOSTIC_TEST: Blood test for estradiol at HCG|DIAGNOSTIC_TEST: Blood test for estradiol at TVOR|DIAGNOSTIC_TEST: Blood test for estradiol at ET|DIAGNOSTIC_TEST: Blood test for estradiol at coordination scan|DIAGNOSTIC_TEST: Endometrial blood flow (doppler) at HCG|DIAGNOSTIC_TEST: Endometrial blood flow (doppler) at TVOR|DIAGNOSTIC_TEST: Endometrial blood flow (doppler) at ET|DIAGNOSTIC_TEST: Endometrial blood flow (doppler) at coordination scan|DIAGNOSTIC_TEST: Contractility at embryo transfer on a subgroup of participants|DIAGNOSTIC_TEST: Change in endometrial pattern between coordination scan and ET|DIAGNOSTIC_TEST: Change in endometrial pattern between HCG and ET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: Usual care|BEHAVIORAL: Lung age|BEHAVIORAL: Contingency Management|BEHAVIORAL: Lung age + Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Of Single Doses Of PF-06291826 (Tafamidis) In Japanese And Western Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tafamidis meglumin|DRUG: Tafamidis meglumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy and Durvalumab, With or Without Tremelimumab, in Patients With Bladder Cancer
Status: WITHDRAWN
Conditions: Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI Assisted Detection of Chest X-Rays
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Nodules, Solitary|Pulmonary Nodules, Multiple|Pulmonary Consolidation|Pneumothorax|Pneumothorax; Acute|Atelectasis|Pulmonary Calcification|Cardiomegaly|Fibrosis Lung|Pleural Effusion|Pleural Effusions, Chronic|Pneumoperitoneum
Interventions: OTHER: Cases reading|OTHER: Ground truthing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Lymphoma|Lymphoproliferative Disorder|Small Intestine Cancer
Interventions: BIOLOGICAL: autologous immunoglobulin idiotype-KLH conjugate vaccine|BIOLOGICAL: sargramostim|DRUG: methotrexate|DRUG: thiotepa|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MagnetisMM-5: Study of Elranatamab (PF-06863135) Monotherapy and Elranatamab + Daratumumab Versus Daratumumab + Pomalidomide + Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elranatamab|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
Status: TERMINATED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: MPC-7869|DRUG: MPC-7869
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using Cumulase for Denudation of Cycles With ≤ 8 Cumulus-oocytes Complexes
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Cumulase denudation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ketamine and Nitroprusside for Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Placebos|DRUG: Ketamine|DRUG: Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotics and Diet to Reduce "Leaky" Gut in First Degree Relatives of Crohn's Disease Patients
Status: COMPLETED
Conditions: Healthy First Degree Relatives of Crohn's Disease Patients
Interventions: DIETARY_SUPPLEMENT: Prebiotics|OTHER: Low n-6 PUFA Diet|DIETARY_SUPPLEMENT: Maltodextrin|OTHER: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Application of Concentrated Growth Factors in Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Ridge Preservation|Concentrated Growth Factor
Interventions: PROCEDURE: bone powder + collagen membrane|PROCEDURE: bone powder + collagen membrane + CGF membrane|PROCEDURE: bone powder mixed wih CGF gel + collagen membrane + CGF membrane|PROCEDURE: bone powder + CGF membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Research of Intranasal Dexmedetomidine Used in Plastic Surgery of Children
Status: UNKNOWN
Conditions: The Efficacy and Safety of Intranasal Dexmedetomidine
Interventions: DRUG: Normal saline,1 milliliter|DRUG: Dexmedetomidine 1 μg.kg-1,1 milliliter|DRUG: Dexmedetomidine 2μg.kg-1,1 milliliter|DRUG: Anesthesia induction, 8% sevoflurane|DRUG: Anesthesia maintenance, 2%~3% sevoflurane,fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional MRI and DTI in the Preoperative Assessment of Dystonia
Status: TERMINATED
Conditions: Isolated Cervical Dystonia|Complex Dystonia|Spasticity
Interventions: OTHER: magnetic resonance imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG
Status: COMPLETED
Conditions: Ocular Hypertension|Open-Angle Glaucoma
Interventions: DRUG: Latanoprost Punctal Plug Delivery System|DRUG: Xalatan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Multi-center Trial Evaluating 5 Fraction Stereotactic Partial Breast Irradiation Using Gammapod
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: Dose Fractionation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Mechanical Methods on the Postpartum Haemorrhage Prophylaxis During Caesarean Section
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Cesarean Section Complications
Interventions: PROCEDURE: Clamping the uterine artery bilaterally during Cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation C-Scan System in Providing Structural Information and Polypoid Lesions in the Colon of Healthy Subjects
Status: COMPLETED
Conditions: Risk for Colorectal Cancer
Interventions: DEVICE: C-Scan System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Acute Effect of Hypericum Perforatum on Short-Term Memory in Healthy Adults
Status: COMPLETED
Conditions: Subclinical Anxious Adults|Nootropic Potential of Hypericum and Alprazolam|Healthy Adults
Interventions: DRUG: Hypericum perforatum extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Application of Cocaine HCl 4%, or 10%, or Placebo Solution in Local (Topical) Anesthesia
Status: COMPLETED
Conditions: Any Ear Nose or Throat Conditions|With Identified Need for a Diagnostic Procedure or Surgery on or Through the Mucous Membranes of the Nasal Cavities
Interventions: DRUG: Cocaine HCl 4% Topical Solution|DRUG: Cocaine HCl 10% Topical Solution|DRUG: Placebo Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesiotaping on Muscular Activity, Mobility, Strength and Pain After Rotator Cuff Surgery
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: kinesiotape|DEVICE: sham tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga for Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Nutrition Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Veress Entry With/Without Concomitant CO2
Status: COMPLETED
Conditions: Laparoscopy|Laparoscopic Surgery|Insufflation|Gynecologic Surgical Procedures
Interventions: PROCEDURE: Veress needle entry with concomitant CO2|PROCEDURE: Veress needle entry with subsequent CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effectiveness of Pharmacist-led Educational Model in Patients With Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis|Pharmaceutical Care|Pharmaceutical Services
Interventions: OTHER: pharmacist-led education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: "Improves Physiological Based Cord Clamping (PBCC) the Systemic and Cerebral Oxygenation in Term Infants?"
Status: COMPLETED
Conditions: Near-Infrared Spectroscopy|Umbilical Cord Issue
Interventions: PROCEDURE: physiological-based cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: SLx-4090|OTHER: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: miRNA in Septic Acute Kidney Injury
Status: RECRUITING
Conditions: Sepsis|Acute Kidney Injury|Acute Kidney Injury Due to Sepsis
Interventions: DIAGNOSTIC_TEST: Laboratory examination to determine the presence of sepsis|DIAGNOSTIC_TEST: Laboratory examination to determine the presence of sepsis and acute kidney injury|DIAGNOSTIC_TEST: Laboratory examination to determine miRNA and biochemical parameters
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Tranexamic Acid in Endoscopic and Microscopic Ear Surgery Cases on Surgeon Satisfaction
Status: NOT_YET_RECRUITING
Conditions: Middle Ear Disease
Interventions: DRUG: Transamine 10% IV/IM Solution for Injection|DRUG: %0.9 Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Acceptance and Commitment Therapy on Serum GDF-15 Levels in Older Adults With and Without Depression: a Non-randomized Intervention Study
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy for people with and without depression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Effects of CC-99677 on the Pharmacokinetics of an Oral Contraceptive in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Oral Contraceptive (Ortho Tri-Cyclen or its generic equivalent)|DRUG: CC-99677
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Platelet-based and Microvesicle-based Assays to Predict Thrombotic and Bleeding Risk in Chronic Kidney Disease Patients With Acute Coronary Syndrome
Status: RECRUITING
Conditions: Chronic Kidney Disease stage3
Interventions: BIOLOGICAL: Blood samples|BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Of SU011248 In Combination With Docetaxel (Taxotere) And Prednisone In Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Prednisone|DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
Status: UNKNOWN
Conditions: Cardiovascular Surgical Procedures|Arthroplasty, Replacement|Hysterectomy
Interventions: BEHAVIORAL: Quality improvement strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Safety and Efficacy of Gabapentin in Postherpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia,Postherpetic
Interventions: DRUG: Gabapentin Extended Release tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AGN-199201 in Patients With Persistent Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Erythema|Rosacea
Interventions: DRUG: AGN-199201|DRUG: Vehicle to AGN-199201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Screening: Digital Breast Tomosynthesis Versus Digital 2D Mammography
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Screening
Interventions: DIAGNOSTIC_TEST: DBT+s2D|DIAGNOSTIC_TEST: 2D-FFDM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Intra-arterial Vasospasm Trial
Status: RECRUITING
Conditions: Cerebral Vasospasm
Interventions: DRUG: Nicardipine|DRUG: Verapamil|DRUG: Nicardipine + Verapamil + Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Analysis of the Effects of the Adana City Training and Research Hospital Obesity Center Training Program on Adult Obese Patients With Binge Eating Disorder. A Prospective, Quasi-experimental Study With Interrupted Time-series Design.
Status: COMPLETED
Conditions: Obesity|Binge-Eating Disorder|Group Meetings|Weight Loss
Interventions: BEHAVIORAL: Multi-disciplinary obesity management therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of ADM in Reduction of Surgical Complexity of Breast Reconstructions With Implants (Nava)
Status: TERMINATED
Conditions: Patients With Breast Cancer Requiring Mastectomy and Suitable for Reconstruction
Interventions: DEVICE: Strattice™ Reconstructive Tissue Matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease
Status: COMPLETED
Conditions: Multicentric Castleman's Disease
Interventions: DRUG: Siltuximab|DRUG: Placebo|DRUG: Best Supportive Care (BSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Transplant Atherosclerosis With Everolimus and Anti-cytomegalovirus Therapy
Status: UNKNOWN
Conditions: Heart Transplantation|Cardiac Allograft Vasculopathy|Cytomegalovirus Infection
Interventions: DRUG: Pre-emptive strategy with valganciclovir plus everolimus|DRUG: Prophylaxis with valganciclovir plus mycophenolate|DRUG: Prophylaxis with valganciclovir plus everolimus|DRUG: Pre-emptive mycophenolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Desloratadine in Patients With Allergic Airway Disease During the Pollen Season (Study P03284)
Status: COMPLETED
Conditions: Allergic Airway Disease
Interventions: DRUG: Desloratadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Usability of Mobile Applications for Monitoring Cutaneous Leishmaniasis Treatment in Colombia
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis, American
Interventions: OTHER: Community based strategy to follow-up pactientes with Cutaneous Leishmaniasis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Sirolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
Status: RECRUITING
Conditions: Asthma|Obesity|Metabolic Syndrome
Interventions: PROCEDURE: Bronchoscopy and Nasal Epithelium Brush Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vaccination of Patients With Renal Cell Cancer With Dendritic Cell Tumor Fusions and GM-CSF
Status: COMPLETED
Conditions: Renal Cancer
Interventions: BIOLOGICAL: Dendritic Cell Tumor Fusion Vaccine|DRUG: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
Status: COMPLETED
Conditions: Hormones
Interventions: BEHAVIORAL: NEA|BEHAVIORAL: DEA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glad Press 'n Seal® as a Temporary Moisture Barrier to Central Lines in Ambulatory Patients
Status: COMPLETED
Conditions: Cancer-related Problem/Condition|Ambulatory Care
Interventions: DEVICE: Glad Press 'n Seal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Utilising Genotype Informed Bayesian Dosing of Tacrolimus in Children Post Solid Organ Transplantation.
Status: RECRUITING
Conditions: Solid Organ Transplant
Interventions: DIAGNOSTIC_TEST: Genotyping for CYP3A4 and CYP3A5 genes|DEVICE: Use of NextDose platform|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section.
Status: RECRUITING
Conditions: Post Operative Pain|Cesarean Section|Tramadol|Postoperative Recovery|Quality of Recovery|Ondansetron|QoR-15|ObsQor-10|Postcesarean Recovery
Interventions: DRUG: Tramadol-ondansetron continuous infusion|DRUG: Ropivacaine via epidural catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Tolerability and Effects of Berberine on Major Metabolic Biomarkers: A Pilot Study
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Berberine|OTHER: Identical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Use of Teledermatology in the Treatment of Patients With Severe Acne on Isotretinoin
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: BEHAVIORAL: Teledermatology visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase IIa Study of KHK4563
Status: COMPLETED
Conditions: Uncontrolled and Suspected Eosinophilic Asthma
Interventions: DRUG: KHK4563|DRUG: KHK4563|DRUG: KHK4563|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal Laser Therapy to Vaginal Estrogen Therapy
Status: COMPLETED
Conditions: Atrophic Vaginitis|Menopause
Interventions: DEVICE: CO2 fractionated vaginal laser|DRUG: Estrogens, Conjugated (USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Design of Tibia Stems in Cemented Total Knee Arthroplasty - Wedge Stem Versus I-beam Stem.
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Maxim TKA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neurotization of the Nipple Areolar Complex to Restore Sensation for Patients With Breast Cancer Undergoing Nipple Sparing Mastectomy and Reconstruction
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8
Interventions: PROCEDURE: Neurotization Procedure|OTHER: Questionnaire Administration|PROCEDURE: Subcutaneous Mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Study of Escalating Multiple Doses of an Iron Chelator in Patients With Iron Overload
Status: COMPLETED
Conditions: Transfusional Iron Overload|Beta-thalassemia
Interventions: DRUG: FBS0701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of AMG 623 in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: AMG 623|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture Combined With Donepezil for Treating Alzheimer's Disease
Status: UNKNOWN
Conditions: Cognitive Impairment
Interventions: PROCEDURE: acupuncture|DRUG: donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the NO-synthase Inhibitor VAS203 on Renal Function in Healthy Volunteers
Status: COMPLETED
Conditions: Renal Function Impairment in Healthy Volunteers
Interventions: DRUG: VAS203|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Non Surgical Protocol for Treatment of Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: PROCEDURE: Mechanical debridement with curettes|PROCEDURE: Er:YAG laser|PROCEDURE: Air Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Gemcitabine|OTHER: Placebo|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Continuous Positive Airway Pressure and Non Invasive Positive Pressure Ventilation
Status: COMPLETED
Conditions: Respiratory Distress of Newborn
Interventions: DEVICE: CPAP|DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artemis Proximal Femoral Nail for Internal Fixation of Intertrochanteric Femur Fractures
Status: RECRUITING
Conditions: Intertrochanteric Fractures|Femoral Fracture|Femoral Neck Fractures
Interventions: DEVICE: Artemis Proximal Femoral Nail (PFN) implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty
Status: COMPLETED
Conditions: Delirium, Dementia, Amnestic, Cognitive Disorders|Arthroplasty, Hip Replacement
Interventions: DEVICE: cemented or cementless type of hip prothesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Application for an Electronic Medication Management Support System
Status: COMPLETED
Conditions: Polypharmacy
Interventions: OTHER: CDSS provides drug-therapy relevant information|OTHER: Modification of medication|OTHER: Assessment of medication appropriateness|OTHER: Medication plan|OTHER: Guidance in medication process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-finding Study of MR-130A-01 Contraceptive Transdermal Patch
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: MR-130A-01 Transdermal patch|DRUG: MR-130A-01 Transdermal patch|DRUG: MR-130A-01 Transdermal patch|DRUG: MR-130A-01 Transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing Oral LT3 Therapy for Heart Failure - HFpEF
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Low Triiodothyronine Syndrome
Interventions: DRUG: liothyronine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Study to Assess the Clinical Utility of Turbidity in Patients Using In-Home Peritoneal Dialysis
Status: RECRUITING
Conditions: End Stage Renal Disease|Peritoneal Dialysis-associated Peritonitis|Peritonitis
Interventions: DEVICE: CloudCath System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
Status: RECRUITING
Conditions: ADNP|Helsmoortel-Van Der Aa Syndrome|Autism Spectrum Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hippotherapy Simulator in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Rehabilitation|Cerebral Palsy, Spastic
Interventions: OTHER: Neurodevelopmental Therapy|DEVICE: Hippotherapy Simulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Progressive Carcinoid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Foregut Neuroendocrine Tumor|Hindgut Neuroendocrine Tumor|Metastatic Digestive System Neuroendocrine Tumor G1|Metastatic Neuroendocrine Tumor|Midgut Neuroendocrine Tumor G1|Neuroendocrine Tumor G2|Recurrent Digestive System Neuroendocrine Tumor G1|Regional Digestive System Neuroendocrine Tumor G1
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Pazopanib Hydrochloride|OTHER: Placebo Administration|OTHER: Quality-of-Life Assessment|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mycotic Ulcer Treatment Trial I
Status: COMPLETED
Conditions: Corneal Ulcer|Eye Infections, Fungal
Interventions: DRUG: Natamycin|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Neoadjuvant Chemoradiotherapy Plus Durvalumab (MEDI4736) in Resectable Stage III NSCLC
Status: RECRUITING
Conditions: Potentially Resectable Stage II/IIIa NSCLC
Interventions: DRUG: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-8583 Single Dose Study in Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants (MK-8583-002)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: MK-8583
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety And Efficacy Of Varenicline and Bupropion For Smoking Cessation In Subjects With And Without A History Of Psychiatric Disorders
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Placebo|DRUG: varenicline tartrate|DRUG: bupropion hydrochloride|DRUG: Nicotine Replacement Therapy Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The EMPATHy Toolkit: Helping Diabetes Patients Overcome Barriers to Medication Adherence
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: EMPATHy Toolkit|BEHAVIORAL: Coached Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacokinetics of Sildenafil in Premature Infants
Status: COMPLETED
Conditions: Persistent Pulmonary Hypertension of the Newborn
Interventions: DRUG: 1 dose of sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physical Exercise as a Sustainability Tool in Men With Dysmetabolic Hypogonadism
Status: RECRUITING
Conditions: Hypogonadism, Male|Metabolic Syndrome|Autonomic Imbalance|Life Style, Healthy|Physical Inactivity
Interventions: BEHAVIORAL: Structured and personalized program of physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LDFWART With Docetaxel in Patients With Platinum-Resistant Recurrent Ovarian Carcinoma
Status: WITHDRAWN
Conditions: Ovarian Cancer|Ovarian Carcinoma|Recurrent Ovarian Cancer|Recurrent Ovarian Carcinoma
Interventions: RADIATION: Low Dose Fractionated Whole Abdominal Radiation Therapy|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent?
Status: UNKNOWN
Conditions: Kidney Stone|Ureter Obstruction|Stent Complication
Interventions: PROCEDURE: Passing a guidewire through a double j stent|PROCEDURE: Double J stent removal and guidewire insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Austrian Polyintervention Study to Prevent Cognitive Decline After Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke|Cognitive Decline|Dementia
Interventions: BEHAVIORAL: Motivation and lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Avanafil in the Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Avanafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid-FES Exercise to Prevent Cardiovascular Declines in Acute SCI
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: FES-row-training|OTHER: Arms-only-row training|OTHER: Time Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Tolerability and Safety of Dexmethylphenidate HCl Extended-Release Capsules in Children With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: ADHD, ADD
Interventions: DRUG: Dexmethylphenidate HCl extended-release capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Precision and Sensitivity of Tilmanocept Uptake Value (TUV) on Tc 99m Tilmanocept Planar Imaging
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tc 99m tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in People With Advanced Cancer to Test How BI 907828 is Processed in the Body
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: [¹⁴C]-BI 907828 mixed with BI 907828 (formulation 1)|DRUG: [¹⁴C]-BI 907828 mixed with BI 907828 (formulation 2)|DRUG: BI 907828
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Determinate Dose, Security and Efficacy or Lenalidomide and Rituximab (LR)-ESHAP in Patients With Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: LR-ESHAP (lenalidomide 5 mg)|DRUG: LR-ESHAP (lenalidomide 10 mg)|DRUG: LR-ESHAP (lenalidomide 15 mg)|DRUG: LR-ESHAP (lenalidomide 20 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DC Vaccine Combined With IL-2 and IFNα-2a in Treating Patients With mRCC
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: Aldesleukin,|BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: recombinant interferon alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Ranibizumab Injection in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion (CRUISE)
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Sham injection|DRUG: Ranibizumab injection 0.3 mg|DRUG: Ranibizumab injection 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Between Auto-titration and Manual Titration of Non-invasive Ventilation in Obesity Hypoventilation Syndrome
Status: COMPLETED
Conditions: Chronic Hypercapnic Respiratory Failure|Obesity Hypoventilation Syndrome
Interventions: DEVICE: Manual Non invasive ventilation titration|DEVICE: Automatic Non invasive ventilation titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Insulin Resistance
Interventions: PROCEDURE: Gastric Bypass w/ matched hypocaloric diet|OTHER: Hypocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Bioavailability Trial With Oral Multiple Dose Administration
Status: COMPLETED
Conditions: Comparative Bioavailability
Interventions: DRUG: GLA-015|DRUG: DAC C-052 "Cannabidiol" / NRF 22.10 "Oily cannabidiol solution 100 mg/ml"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER