pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: vinblastine sulfate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Ostom-i Alert Sensor on Quality of Life in Patients With Ileostomy
Status: TERMINATED
Conditions: Ostomy
Interventions: DEVICE: Ostom-i Alert Sensor|OTHER: No Ostom-i Alert Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MTD, Safety and Efficacy of NYH817G and NYH100P in Monotherapy and Combination in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: NYH817G|DRUG: NYH100P|DRUG: NYH817G and NYH100P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Flow Nasal Oxygen Cannula Compared to Non-Invasive Ventilation in Adult Patients With AcuTE Respiratory Failure
Status: COMPLETED
Conditions: Respiratory Insufficiency|Respiratory Failure
Interventions: DEVICE: High Flow Nasal Catheter|DEVICE: Noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Diagnostic Yield Between R-EBUS Guided Cryo Biopsy Vs. CT Guided Biopsy for PPL
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: PROCEDURE: CT guided core biopsy|PROCEDURE: Cryo-biopsy via Radial EBUS navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer
Status: RECRUITING
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: Nanoliposomal Irinotecan|DRUG: Leucovorin|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CP-547,632 in Treating Patients With Recurrent or Persistent Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: CP-547,632
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Efficacy in HELLP I Syndrome
Status: UNKNOWN
Conditions: HELLP Syndrome
Interventions: DRUG: Dexamethasone|DRUG: sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Tolerability Study of TRAVATAN® Versus LUMIGAN®
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Travoprost 0.004% ophthalmic solution|DRUG: Bimatoprost 0.01% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Levodopa Pharmacokinetics Following Single Dose Administration of CVT 301 (Levodopa Inhalation Powder) in Smoking and Non-Smoking Adults
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: CVT-301|DRUG: Carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harmonic Ratio in Patients With GLUT1 Deficiency Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: GLUT1DS1|Dystonia|Gait Disorders, Neurologic|Gait Ataxia
Interventions: DIAGNOSTIC_TEST: Inertial gait analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer Receiving Postoperative Radiotherapy and Concurrent Chemotherapy
Status: COMPLETED
Conditions: Mucositis|Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: palifermin|RADIATION: Radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lipoprotein-associated Phospholipase A2 (Lp-PLA2) Progenitor Cells and Coronary Atherosclerosis in Humans
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DRUG: darapladib|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Pressure Changes Using Esophageal Balloon Catheter (OBC) in Laparoscopic Surgery
Status: COMPLETED
Conditions: Ventilator Lung
Interventions: DEVICE: Adult esophageal balloon catheter (obc)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopic Proximal Gastrectomy With Double-flap Technique Versus Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction for Proximal Early Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: Laparoscopic Proximal Gastrectomy With Double-flap Technique|PROCEDURE: Laparoscopic Total Gastrectomy With Roux-en-Y Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Intolerance in Elderly Patients With HFpEF(Heart Failure With Preserved Ejection Fraction)
Status: COMPLETED
Conditions: Heart Failure, Diastolic|Obesity
Interventions: BEHAVIORAL: dietary, aerobic and resistance training|BEHAVIORAL: dietary, and aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|High Risk Myelodysplastic Syndrome|Myelodysplastic Syndrome|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Gemtuzumab Ozogamicin|DRUG: Liposome-encapsulated Daunorubicin-Cytarabine|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Cardiac Safety of Oritavancin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Single-Dose IV Oritavancin Diphosphate|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of Topically Applied 40% Lidocaine Gel Compared With Placebo in Subjects With Acute Herpes Zoster (Shingles) Pain
Status: TERMINATED
Conditions: Acute-onset Herpes Zoster Pain
Interventions: DRUG: CNTX-2022 (lidocaine gel, 40%)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test GlaxoSmithKline's (GSK) Herpes Zoster (HZ) Subunit Vaccine's Long-term Immune Response in Previously Vaccinated Kidney Transplant Adults and Then to Test if 2 Additional Doses of the Vaccine Are Safe and Able to Generate an Immune Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: HZ/su vaccine (GSK1437173A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Plaque Formation Rate and Toothpaste
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: AmF/SnF2|OTHER: mHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Treatment Outcomes of Anterior Open Bite Treated by Temporary Anchorage Devices
Status: ENROLLING_BY_INVITATION
Conditions: Anterior Openbite Malocclusion
Interventions: OTHER: Temporary Anchorage Devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Hydroxyurea|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Temozolomide With or Without Radiation Therapy to the Brain in Treating Patients With Stage IV Melanoma That Is Metastatic to the Brain
Status: TERMINATED
Conditions: Melanoma (Skin)|Metastatic Cancer
Interventions: DRUG: temozolomide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of ACP-196 and Pembrolizumab in Subjects With Platinum Resistant Urothelial Bladder Cancer
Status: COMPLETED
Conditions: Metastatic Urothelial Carcinoma
Interventions: DRUG: pembrolizumab|DRUG: ACP-196 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD)
Status: COMPLETED
Conditions: Late Infantile Metachromatic Leukodystrophy
Interventions: BIOLOGICAL: Recombinant human Arylsulfatase A (rhASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Chemotherapy and Radiotherapy in Newly Diagnosed Metastatic Nasopharyngeal Carcinoma: A Multicenter Study
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: OTHER: Immunotherapy+induction chemotherapy+radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Bortezomib, Cytarabine, and Dexamethasone in Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Bortezomib, Cytarabine, Dexamethasone, Pegteograstim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Value of Trio Exome Sequencing in the Etiological Assessment of Specific Non-syndromic Language and Learning Disorders
Status: RECRUITING
Conditions: Specific Language and Learning Disorders (SLLD)
Interventions: BIOLOGICAL: Blood samples|OTHER: Consultation for results delivery|OTHER: Study Humanities and Social Sciences
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, B-Cell
Interventions: DRUG: AEG35156 antisense IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blind, Randomized Study Of The Analgesic Efficacy And Safety Of Valdecoxib 20 Mg Daily And Valdecoxib 20 Mg Twice Daily Compared To Placebo For Management Of Acute Postsurgical Pain In Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: placebo|DRUG: valdecoxib|DRUG: valdecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability and to Assess the Effect of Food on the Bioavailability of a TAK-648 Tablet in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-648 Tablet|DRUG: TAK-648 Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms of the Prostate
Interventions: DEVICE: AuroShell particle infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Clinical Trial on The Use of a Specific Antivenom Against Envenoming by Bungarus Multicinctus
Status: COMPLETED
Conditions: Snake Bite
Interventions: DRUG: Bungarus multicinctus-candidus Antivenom|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Mouthrinses Based on Chlorhexidine 0.12% and CITROX®
Status: ACTIVE_NOT_RECRUITING
Conditions: Periodontitis
Interventions: DEVICE: Mouthwash with chlorhexidine 0,12% and CITROX|DEVICE: Mouthwash with chlorhexidine 0,12%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Bioequivalence of VIAject®7 Compared to VIAject®25 and Comparing the Pharmacokinetic and Pharmacodynamic Properties of VIAject®7 to Insulin Lispro in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: VIAject®25|DRUG: VIAject®7|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Olaparib With Cisplatin Based Chemoradiotherapy in Squamous Cell Carcinoma of the Head and Neck
Status: WITHDRAWN
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: olaparib|DRUG: cisplatin|RADIATION: Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha-1 Antitrypsin Deficiency
Interventions: DRUG: rAAV1-CB-hAAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1356/metformin|DRUG: BI 1356|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Staccato Alprazolam Versus Oral Alprazolam in Healthy Study Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Staccato alprazolam|DRUG: Oral alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Bilateral Erector Spina Plane Block on Postoperative Pain in Adult Cardiac Surgery.
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Use
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Ocrelizumab VErsus Rituximab Off-Label at the Onset of Relapsing MS Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Rituximab|DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-dependent Effects of Oxytocin on the Amygdala and Reward System
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Initiation of Chronic Asthma Care Regimens in the Pediatric Emergency Department
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Intervention: Budesonide|DRUG: Usual care: albuterol + systemic steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Model of Vocal Inflammation and Tissue Mobilization
Status: COMPLETED
Conditions: Acute Phonotrauma
Interventions: BEHAVIORAL: resonant voice|BEHAVIORAL: voice rest|BEHAVIORAL: Breathy voice|BEHAVIORAL: Relaxation exercise|BEHAVIORAL: Resonant voice and relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of NDI-034858 in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: NDI-034858 study drug|DRUG: NDI-034858 study drug|DRUG: NDI-034858 study drug|DRUG: NDI-034858 study drug|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Surgery on Obstructive Sleep Apnea in Obese Patients: an Open-label Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: To Compare the Difference of AHI Variation Between LSG and Combined Surgery
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy（LSG）|PROCEDURE: Uvulopalatopharyngoplasty(UPPP) and Adenoidectomy/Tonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Temperature Control in Body Contouring Procedures
Status: COMPLETED
Conditions: Hypothermia|Postoperative Pain|Postoperative Nausea|Postoperative Complications|Postoperative Shivering|Postoperative Hemorrhage
Interventions: OTHER: Control - Standard Strategies for hypothermia prevention|OTHER: Fluid warming before infusion and infiltration|DEVICE: Thermal convection blanket by water flow (Blanketrol)|DEVICE: Conductive fabric electric warming device (HotDog)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cemiplimab/Peg-Interferon-α in Advanced CSCC
Status: WITHDRAWN
Conditions: Cutaneous Squamous Cell Carcinoma|Squamous Cell Carcinoma|Advanced Squamous Cell Carcinoma
Interventions: DRUG: Cemiplimab-Rwlc|DRUG: PEG-IFN alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced-dose Botox for Urgency Incontinence Among Elder Females
Status: RECRUITING
Conditions: Overactive Bladder|Urinary Incontinence in Old Age|Urgency Urinary Incontinence
Interventions: DRUG: Botox 50 Unit Injection|DRUG: Botox 100 Unit Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study, Called RegoFlex EU, to Learn More About the Use of Stivarga at Reduced Doses as Recommended (Flexible Dosing) to Treat People With Metastatic Colorectal Cancer in Real World Settings in Europe
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: Retrospective patient chart review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypofractionated Stereotactic Radiotherapy for Patients With Recurrent High Grade Glioma
Status: COMPLETED
Conditions: Recurrent High Grade Glioma
Interventions: RADIATION: IMRT with or without radiosensitive therapy|DRUG: Radiosensitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Fungal Prophylaxis|Candida Infection|Critical Illness|Surgery
Interventions: DRUG: Nystatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: CNP520|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Comparison of Two Different Methods of Partial Inflation of Cuff for Facile Insertion of Laryngeal Mask Airway in Pediatric Patients
Status: COMPLETED
Conditions: Surgical Complications From General Anesthesia
Interventions: DEVICE: The cuff inflation by the resting volume|DEVICE: The cuff inflation by the maximum volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Recovering Strategy on Forward Head Posture in Chinese Adolescents: Tai Chi and Manual Therapy
Status: COMPLETED
Conditions: Forward Head Posture
Interventions: BEHAVIORAL: Manual therapy|BEHAVIORAL: Tai Chi|BEHAVIORAL: Tai Chi and Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Knemometry Study to Compare the Systemic Safety of Flutiform pMDI, Fluticasone pMDI and Beclometasone Autohaler in Paediatric Subjects Aged 5 to Less Than 12 Years.
Status: COMPLETED
Conditions: Mild Persistent Asthma
Interventions: DRUG: Flutiform 50/5 ug (2 puffs bid) pMDI|DRUG: Fluticasone 50 ug (2puffs bid) pMDI|DRUG: Beclometasone Autohaler 50 ug (2 puffs bid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration
Status: RECRUITING
Conditions: Sarcopenia|Connective Tissue Diseases in Old Age|Musculoskeletal Abnormalities
Interventions: DEVICE: Low-magnitude High-frequency Vibration|DIETARY_SUPPLEMENT: β-hydroxy β-methylbutyrate (HMB) supplement|DIETARY_SUPPLEMENT: Protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of the Role of Action Observation in the Post-operative Rehabilitation of the Total Knee Prosthesis: (LOARAL 2)
Status: RECRUITING
Conditions: Knee Surgery|Rehabilitation|Point Light Display
Interventions: OTHER: Point light display
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Short-term Theta Frequency Stimulation of the Vagus Nerve on Cognition in Patients With Refractory Epilepsy
Status: TERMINATED
Conditions: Refractory Epilepsy
Interventions: OTHER: no stimulation|OTHER: beta (25-30 Hz)|OTHER: Theta (5 Hz)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Prevents Chemobrain in Breast Cancer Patients
Status: COMPLETED
Conditions: Chemo-brain|Drug-Related Side Effects and Adverse Reactions|Mild Cognitive Impairment|Breast Cancer
Interventions: PROCEDURE: Dense cranial electroacupuncture stimulation|PROCEDURE: Body acupuncture|PROCEDURE: Least acupuncture stimulation|DRUG: Cytoxan-containing chemotherapy regimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of the Communication Between the Nursing Staff and the Patient on the Analgesic Treatment Effectiveness After Surgery
Status: RECRUITING
Conditions: Post-operative Pain
Interventions: OTHER: Communication between nursing staff and participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing the Effects of CytoSorb Hemoperfusion on the Development on Immunoparalysis
Status: COMPLETED
Conditions: Sepsis|Immune Deficiency|Hemoperfusion|Blood Purification
Interventions: DEVICE: CytoSorb hemoperfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Phenotype, Calprotectin and Mmp-8 Levels in Cases Diagnosed With Peri-implant Disease
Status: COMPLETED
Conditions: Peri-implant Mucositis|Peri-Implantitis
Interventions: PROCEDURE: Non-surgical mechanical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Cognitive Training Program, Goal Management Training, on Reducing Cognitive Difficulties and Improving Every-day Functioning in Individuals With Affective Disorders
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder|Cognitive Dysfunction
Interventions: BEHAVIORAL: Goal Management Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Geistlich Bio Oss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tamsulosin vs Placebo to Prevent Postoperative Urinary Retention in Female Pelvic Reconstructive Surgery
Status: COMPLETED
Conditions: Urinary Retention|Lower Urinary Tract Symptoms|Stress Urinary Incontinence|Pelvic Organ Prolapse
Interventions: DRUG: Placebo oral capsule|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quadratus Lumborum Block With TAP Block for Postoperative Analgesia After Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Transversus Abdominis Plane (TAP) Block|OTHER: Quadratus Lumborum (QL) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Trastuzumab Emtansine Versus Taxane in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Advanced Gastric Cancer
Status: TERMINATED
Conditions: Gastric Cancer
Interventions: DRUG: Taxane|DRUG: trastuzumab emtansine|DRUG: trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Hepatic Arterial Infusion Combined With Bevacizumab and Sintilimab for Unresectable A-staged Hepatocellular Carcinoma in BCLC Classification (D-TRIPLET)
Status: UNKNOWN
Conditions: Unresectable Hepatocellular Carcinoma|Hepatocellular Carcinoma by BCLC Stage
Interventions: DRUG: Hepatic Arterial Infusion(mFOLFOX7) combined with Bevacizumab and Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moringa Supplementation for Improved Milk Output
Status: RECRUITING
Conditions: Breastfeeding
Interventions: DIETARY_SUPPLEMENT: Moringa leaf powder|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Macular Pigment Augmentation on Dark Adaptation
Status: TERMINATED
Conditions: Aging|Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: ZeaVision EyePromise Restore|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Technology-assisted, High Intensive, Task-oriented Exercise Trial
Status: UNKNOWN
Conditions: Stroke|Cerebrovascular Disorders|Brain Diseases|Central Nervous System Diseases|Vascular Diseases|Nervous System Diseases|Cerebral Infarction|Brain Ischemia
Interventions: DEVICE: Orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive, Low-dose tPA in Primary PCI for STEMI
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: DRUG: tissue plasminogen activator|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Chewing Sugarless Gum for Reduction of Orthodontic Appliance Pain
Status: COMPLETED
Conditions: Pain Associated With Fixed Orthodontic Treatment
Interventions: OTHER: Chewing Sugarless Gum|OTHER: Using Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Terlipressin on Intesitnal Function in Septic Shock Patients
Status: UNKNOWN
Conditions: Terlipressin|Septic Shock
Interventions: DRUG: Terlipressin|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Virgin Coconut Oil (VCO) on Cardiometabolic Parameters in Patients With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Atorvastatin 10mg|DIETARY_SUPPLEMENT: Virgin Coconut Oil (VCO)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anthocyanin Rich Extract (ACRE) in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Standardized anthocyanin-rich extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Paste Type Acellular Dermal Matrix(CG Paste) in Chronic Wound Healing
Status: UNKNOWN
Conditions: Chronic Wound
Interventions: DEVICE: application of CG Paste+EasyFoam|DEVICE: application of EasyFoam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Effect on A Disintegrin-like And Metalloprotease Thrombospondin1 Motif 13& Interleukin 6 in Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Vitamin D Deficiency|ADAMTS13|Interleukin 6
Interventions: DRUG: Cholecalciferol 2800 I.U. ml oral drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Widefield Angiography Guided Targeted-retinal Photocoagulation Combined With Anti VEgf Intravitreal Injections for the Treatment of Ischemic Central Retinal Vein Occlusion, Hemi Retinal Vein Occlusion, and Branch Retinal Vein Occlusion
Status: COMPLETED
Conditions: Central Retinal, Hemi Retinal & Brach Retinal Vein Occlusions
Interventions: DRUG: 0.5mg Ranibizumab|PROCEDURE: Targeted Pan Retinal Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin AM or PM: Effect on Circadian Rhythm of Platelet Reactivity
Status: COMPLETED
Conditions: Aspirin|Circadian Rhythm|Platelet Activation|Cardiovascular Diseases
Interventions: BEHAVIORAL: change time of intake of aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: School-based Treatment of Social Anxiety With Developmentally Oriented Cognitive Therapy for Social Anxiety Disorder
Status: RECRUITING
Conditions: Social Anxiety Disorder|Social Anxiety|Adolescent - Emotional Problem
Interventions: BEHAVIORAL: DOCT-SAD|BEHAVIORAL: SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure on Postoperative Pain With Gynecologıcal Surgery
Status: COMPLETED
Conditions: Acupressure|Post Operative Pain|Nurse's Role
Interventions: OTHER: acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Mix of Probiotics in Athletes Performance
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Probiotic capsule|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiopulmonary Protective Effects of Modified Remote Ischaemic Preconditioning in Mitral Valve Replacement Surgery
Status: COMPLETED
Conditions: Myocardial Injury|Remote Ischemic Preconditioning
Interventions: PROCEDURE: Modified Remote Ischemic Preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Arterial Stiffness as a Predictor of Response to Renal Sympathetic Denervation
Status: COMPLETED
Conditions: Therapy Resistant Arterial Hypertension
Interventions: DEVICE: Renal sympathetic denervation (RDN)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Add On Aliskiren in Patients With Heart Failure and Renal Impairment
Status: TERMINATED
Conditions: Heart Failure|Kidney Failure
Interventions: DRUG: Aliskiren|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Reliability and Usability of the Reusable "BrownieForSymphony" Pump Set in Home Use
Status: COMPLETED
Conditions: Lactation
Interventions: DEVICE: Pumping CE-marked Symphony Pumpset|DEVICE: Pumping BrownieForSymphony Pumpset
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Extracorporeal Shock Wave Therapy in Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Trigger Point Pain
Interventions: OTHER: ESWT Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Electroconvulsive Therapy (ECT) Versus Aripiprazole in Clozapine-resistant Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Clozapine Resistant Schizophrenia
Interventions: PROCEDURE: maintenance ECT|DRUG: Aripiprazole tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Golimumab 100 mg|BIOLOGICAL: Golimumab 200 mg|BIOLOGICAL: Golimumab 400 mg|BIOLOGICAL: Golimumab 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized, Placebo-controlled Study Evaluating Efficacy and Safety of IgPro20 in Post-COVID-19 POTS
Status: NOT_YET_RECRUITING
Conditions: Post-COVID Postural Orthostatic Tachycardia Syndrome
Interventions: BIOLOGICAL: IgPro20|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flumatinib in CML-CP Patients With Ph+ Post Imatinib Failure
Status: UNKNOWN
Conditions: Flumatinib|Chronic Myeloid Leukemia, Chronic Phase|Imatinib
Interventions: DRUG: Flumatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Japanese Phase 1/2 Study to Assess the Efficacy, Safety and Pharmacokinetics of Romidepsin in Patients With Peripheral T-cell Lymphoma (PTCL)
Status: COMPLETED
Conditions: Lymphoma, T-cell, Peripheral
Interventions: DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Whole Body Vibration in People With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Whole body vibration therapy|DEVICE: Exercise on the vibration platform with the device turned off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel in Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: Docetaxel + carboplatin + radiotherapy + docetaxel + gemcitabine|OTHER: Docetaxel + gemcitabine + carboplatin + radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Red Light Treatment in Peripheral Artery Disease
Status: RECRUITING
Conditions: Peripheral Artery Disease|Claudication, Intermittent|Vasodilation
Interventions: DEVICE: Red Light (670 nm energy)|DRUG: Octafluoropropane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physical Exercise and Telephone Follow-up Mediated by Telerehabilitation
Status: RECRUITING
Conditions: Cardiac Failure
Interventions: OTHER: conventional rehabilitation|BEHAVIORAL: Education|OTHER: telerehabilitation|BEHAVIORAL: follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Somatostatin Analogues With Perioperative Antibiotics Versus Prolonged Antibiotics
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatic Diseases
Interventions: DRUG: Somatostatin analog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gait Rehabilitation Following an Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Complete Tear, Knee, Anterior Cruciate Ligament
Interventions: OTHER: Gait rehabilitating with reduced bodyweight|OTHER: Standardized rehabilitation following an anterior cruciate ligament reconstruction at Linkoping University Hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at Performance of MICRUSFRAME and GALAXY Coils for the Treatment of Intracranial Aneurysms
Status: ACTIVE_NOT_RECRUITING
Conditions: Aneurysms
Interventions: DEVICE: MICRUSFRAME and GALAXY coils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis Values
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Hypertonic saline|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Inhaled Treprostinil Sodium for the Treatment of Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis|Pulmonary Hypertension
Interventions: DRUG: Treprostinil sodium for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: LY3372689|DRUG: LY3372689|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: DNA analysis|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 in Healthy and Obese Adult Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: NO-13065|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain in Children With Cerebral Palsy After Pelvic and Femoral Osteotomies
Status: COMPLETED
Conditions: Postoperative Pain|Cerebral Palsy
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Pharmacodynamic Response of Faster Acting Insulin Aspart in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children
Status: TERMINATED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DRUG: Prednisolone and amoxicillin/clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A RCT Study of ERAS in Infants With Choledochal Cyst
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery|Infant ALL|Cholangiectasis
Interventions: BEHAVIORAL: Perioperative accelerated rehabilitation surgical measures|BEHAVIORAL: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: NAFLD
Interventions: BIOLOGICAL: RYI-018|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Adenovirus Type 5 Injection Combined With PD-1 Monoclonal Antibody and Nab-paclitaxel in the Treatment of Patients With Liver Metastases From Malignant Melanoma
Status: NOT_YET_RECRUITING
Conditions: Malignant Melanoma|Liver Metastases
Interventions: DRUG: Recombinant Human Adenovirus Type 5 Injection,Camrelizumab,Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: Lapatinib|BIOLOGICAL: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Free Skin Grafting to Reconstruct Donor Sites After Radial Forearm Flap Harvesting
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Platelet-rich fibrin (PRF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 6-Month Study Of CP-690,550 Versus Tacrolimus In Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION