pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Standard ACL Reconstruction vs ACL + Lateral Extra-Articular Tenodesis Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Lateral Extra-Articular Tenodesis (LET)|PROCEDURE: ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK and PD Responses to Oral L-Citrulline in Patients With Sickle Cell Disease
Status: UNKNOWN
Conditions: Sickle Cell Disease
Interventions: DRUG: L-citrulline tablets, 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ia Clinical Study to Evaluate the Safety, Tolerability, PK and Immunogenicity of YBSW015 in Healthy Subjects
Status: UNKNOWN
Conditions: Coronavirus Disease 2019
Interventions: BIOLOGICAL: YBSW015 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Establish the Safety and Tolerability of Zimura® (Anti-C5 Aptamer) in Combination With Anti-VEGF Therapy in Subjects With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV)
Status: COMPLETED
Conditions: Idiopathic Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Zimura
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Head Position Improve Surgical Field During Ear Surgery?
Status: COMPLETED
Conditions: Intra-operative Bleeding
Interventions: PROCEDURE: Head-Up Position|DRUG: Dexmedetomidine|DRUG: Induction and maintenance of anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy/Safety/Subject Satisfaction/Duration of Response of Clobetasol Propionate Spray vs Ointment in Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: clobetasol propionate spray|DRUG: clobetasol propionate ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy
Status: RECRUITING
Conditions: Leprosy|Leprosy, Multibacillary|Neglected Tropical Diseases
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study To Evaluate A Pharmacologically Active Nasal Sponge Following Endoscopic Sinus Surgery
Status: WITHDRAWN
Conditions: Sinusitis|Chronic Sinusitis
Interventions: DRUG: Bacitracin|PROCEDURE: Nasopore sponge soaked with saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apitox, Honeybee Venom Treatment for Osteoarthritis Pain and Inflammation
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: honeybee venom (Apitoxin (Korea) Apitox (USA))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Integral Respiratory Rehabilitation Program in Oncological Patient With Disney
Status: COMPLETED
Conditions: Occupational Therapy|Cancer|Dyspnea|Rehabilitation
Interventions: PROCEDURE: Comprehensive functional care plan|PROCEDURE: Traditional intervention without rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Modulation of Peripheral Nerve Excitability
Status: NOT_YET_RECRUITING
Conditions: Peripheral Neuropathy
Interventions: DRUG: Topical lidocaine 5%|DRUG: Topical Phenytoin 10%|DRUG: Topical Mepyramine 2%|OTHER: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study
Status: UNKNOWN
Conditions: Rhinitis, Seasonal, Allergic
Interventions: DRUG: PSE 120 mg, CM 8 mg, Atr 0.36 mg|DRUG: PSE 120 mg, CM 8 mg, Atr 0.24 mg|DRUG: PSE 120 mg, CM 8 mg, Atr 0.12 mg|DRUG: PSE 120 mg, CM 8 mg|DRUG: Atropine 0.24 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ROBERT® as an Intervention to Enhance Muscle Strength After Spinal Cord Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: OTHER: Robert - intervention to enhance muscle strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Orally Administered AG-881 in Patients With Advanced Solid Tumors, Including Gliomas, With an IDH1 and/or IDH2 Mutation
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: AG881
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GA101-miniCHOP Regimen for the Treatment of Elderly Unfit Patients With Diffuse Large B-cell Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: CD20 Positive Diffuse Large B-cell Lymphoma|Elderly Unfit Patients
Interventions: DRUG: Ga101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I-II Study in CD30 Positive Diffuse Large B-cell Lymphoma Patients Refractory to First Line Chemotherapy or in First Relapse
Status: RECRUITING
Conditions: DLBCL
Interventions: COMBINATION_PRODUCT: R-DHAP|DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Diaphragmatic Breathing Exercises on Fetal Anxiety and Coping With Prenatal Stress
Status: COMPLETED
Conditions: Coping With Prenatal Stress|Fetal Health Anxiety
Interventions: OTHER: Diaphragmatic Breathing Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer
Status: RECRUITING
Conditions: Anaplastic Thyroid Cancer|Relapsed/Refractory Poorly Differentiated Thyroid Cancer
Interventions: BIOLOGICAL: AIC100 CAR T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAGnesium Effect With ANtiosteoporotic Drugs
Status: RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: OTHER: Follow-up of patients with postmenopausal osteoporosis, with or without fractures, requiring initiation of injectable bisphosphonate therapy as part of their usual care|DRUG: Follow-up of patients with postmenopausal osteoporosis, fractured or not, requiring initiation of injectable bisphosphonate therapy as part of care with magnesium supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Decitabin Based Conditioning Regimen Followed With Post-HSCT Decitabin Maintenance Therapy in TP53 Mutant AML/MDS Patients
Status: RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|TP53
Interventions: DRUG: VEN and DEC based conditioning regimen|DRUG: DEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobilization With Movement and Progressive Strengthening Exercises in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Mobilization with movement lateral Glides and Conventional Physiotherapy|OTHER: Progressive Resistance Exercises and Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Role of the Guidewire in Peripheral Intravenous Access
Status: WITHDRAWN
Conditions: Peripheral Intravenous Vein Catheter Phlebitis|Intravenous Infection
Interventions: DEVICE: B.Braun 6.35 cm 20 Gauge ultralong intravenous catheter|DEVICE: B.D Accucath 5.71 cm 20 Gauge ultralong intravenous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Oral Lorlatinib in Patients With Relapsed ALK Positive Lymphoma
Status: RECRUITING
Conditions: Anaplastic Large Cell Lymphoma, ALK-Positive
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propofol Based Versus Volatile Based Anesthesia and Postoperative Sedation
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: Isoflurane/sevoflurane|OTHER: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: New Digital Person-based Care Model in Patients With HER2-negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Narrative Medicine|HER2-negative Breast Cancer|Patient Satisfaction
Interventions: BEHAVIORAL: introduction of digital listening may improve the quality of life of patients withe breast cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Chemotherapy Before and After Surgery for Stage II,III Esophageal Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Esophageal Neoplasms|Carcinoma, Squamous Cell
Interventions: DRUG: Surgery +(Cisplatin 80 mg/㎡+5FU 800mg/㎡×5days)×2|DRUG: (Cisplatin 80 mg/㎡+5FU 800mg/㎡×5days)×2＋Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Treatment in Patients With Mild Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury With Brief Loss of Consciousness
Interventions: BEHAVIORAL: primary care follow up|BEHAVIORAL: Multidisciplinary follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study to Investigate the Safety, Tolerability and Pharmacokinetics of MAS825 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MAS825|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Use Disorder|Trauma Injury|Alcohol Dependence|Alcohol Abuse
Interventions: DEVICE: Real iTBS to the dlPFC|DEVICE: Sham iTBS to the dlPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COrporeal Compression at the ONset of Severe Sepsis and Septic Shock
Status: COMPLETED
Conditions: Severe Sepsis or Septic Shock|Fluid Resuscitation
Interventions: OTHER: Whole-body compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a Group Intervention on Breast Cancer Patient's Adjustment and Emotion Regulation at the End of Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Cognitive-behavioral therapy and hypnosis group|BEHAVIORAL: Support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Study in Chinese Patients With Lower Extremity Ankle Fracture of Oral Anticoagulants to Prevent Venous Thromboembolism (VTE)
Status: UNKNOWN
Conditions: Foot Ankle Injuries|Anticoagulants and Bleeding Disorders|Venous Thromboembolism
Interventions: DRUG: Apixaban Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of The Effects Of Carbetocin And Oxytocin In C-Sectıon
Status: NOT_YET_RECRUITING
Conditions: Carbetocin|Oxytocic Drugs Causing Adverse Effects in Therapeutic Use
Interventions: PROCEDURE: C-sections operations|DRUG: Oxytocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mayo AVC Registry and Biobank
Status: RECRUITING
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy|Cardiomyopathies|Heart Diseases|Cardiovascular Diseases|Sudden Cardiac Arrest|Sudden Cardiac Death|Arrhythmogenic Right Ventricular Dysplasia|Arrhythmogenic Ventricular Cardiomyopathy|Familial Dilated Cardiomyopathy|Cardiovascular Abnormalities|Sarcoidosis|Cardiac Arrhythmia|Cardiac Sarcoidosis|Myocarditis|Inflammatory Cardiomyopathy|Ventricular Tachycardia|Right Ventricular Outflow Tract Ventricular Tachycardia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Penn Medicine Biobank Return of Results Program
Status: ENROLLING_BY_INVITATION
Conditions: Genetic Disease|Cancer|Cardiovascular Diseases
Interventions: OTHER: private web-portal eHealth disclosure of genetic results|OTHER: eHealth education intervention (web or chatbot)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Whole-body Vibration Training on Sarcopenic Elderly
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: DEVICE: whole body vibration plus conventional therapy|PROCEDURE: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pharmacokinetic and Safety Study of Paliperidone Palmitate (JNS010) in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Music and Natural Landscape Paintings on Pain Level, Anxiety and Analgesic Use of Women During HSG
Status: RECRUITING
Conditions: Hysterosalpingography|Anxiety|Pain
Interventions: OTHER: music group|OTHER: video group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effects of Adding a Home Exercise Program to a Clinical Physical Therapy Program on Cancer-Related Fatigue
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Clinic-based physical therapy program.|OTHER: Home exercise program.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of EGF-loaded Self Healing Gel in Treatment of Oral Mucositis
Status: UNKNOWN
Conditions: Oral Mucositis
Interventions: DRUG: EGF loaded Hydrogel|DRUG: Hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Post Burn Rehabilitation Population for Itch Control
Status: COMPLETED
Conditions: Pruritus|Itching|Burn Pruritus
Interventions: OTHER: Provase|OTHER: Control moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Surgical Templates in the Surgical Exposure of Impacted Canines
Status: ACTIVE_NOT_RECRUITING
Conditions: Impacted Tooth
Interventions: OTHER: Palatally impacted canine exposure using a surgical guide|OTHER: Palatally impacted canine exposure using the conventional free.hand method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Appropriate Sedation for Patients After Abdominal Surgeries : A Prospective Randomised Controlled Study
Status: COMPLETED
Conditions: Postoperative Sedation, Abdominal Surgery
Interventions: DRUG: Dexmedetomidine, tramadol and flurbiprofen|DRUG: tramadol and flurbiprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Benefit Evaluation of Ambulatory Activity Combining Rehabilitation and Therapeutic Education, Using an Intelligent Electric Bike for the Health, for the Effort Rehabilitation and the Quality of Life Improvement for Patients Suffering of Moderate Fibromyalgia (FIBROVELIS)
Status: UNKNOWN
Conditions: Fibromyalgia|Chronic Pain|Adapted Physical Activity|Therapeutic Education|Electric Bike
Interventions: OTHER: Ambulatory activity combining rehabilitation and therapeutic education, using an Intelligent Electric Bike for the Health.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Automated Oxygen Titration During Walking in Patients With Lung Fibrosis (OXYWILD)
Status: RECRUITING
Conditions: Fibrosis Lung|Respiratory Therapy
Interventions: OTHER: Automated variable dose oxygen treatment|OTHER: Fixed dose oxygen treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PEAK PlasmaBlade™ 4.0 Versus Traditional Electrosurgery in Lumpectomy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DEVICE: PEAK PlasmaBlade|PROCEDURE: Traditional Electrosurgery with scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Protein-Enriched Meal on Liver, Kidney or Bone: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Weight Reduction|Obesity|Weight Management
Interventions: DIETARY_SUPPLEMENT: Herbalife Meal Replacements|DIETARY_SUPPLEMENT: Herbalife Meal Replacements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Experiential Training in Eliciting Disclosure & Emotions for Mental Health Trainees
Status: COMPLETED
Conditions: Trauma|Emotions|Disclosure
Interventions: BEHAVIORAL: Experiential Psychotherapy Skill Training|BEHAVIORAL: Standard Psychotherapy Skill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
Status: RECRUITING
Conditions: Radius Fracture Distal|Pain, Postoperative
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in EpCAM Positive Patients With Symptomatic Malignant Ascites Using Removab Versus an Untreated Control Group
Status: COMPLETED
Conditions: EpCam Positive Tumor (e.g.Ovarian, Gastric, Colon, Breast)|Malignant Ascites
Interventions: BIOLOGICAL: Catumaxomab (Removab)|PROCEDURE: paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Full-Weightbearing Following Ankle Fractures Surgically Treated - The FAST-Mobility Trial
Status: UNKNOWN
Conditions: Rehabilitation of Surgically Treated Ankle Fractures
Interventions: PROCEDURE: Early pain dependent weight-bearing without immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Infiltration Analgesia in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Analgesia
Interventions: DRUG: Ropivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Biomarkers of AV-101
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: AV-101 720 mg|DRUG: AV-101 1440 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraocular Pressure and Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomies
Status: WITHDRAWN
Conditions: Intraocular Pressure|Intracranial Pressure|Pneumoperitoneum
Interventions: DIAGNOSTIC_TEST: Intraocular pressure measurement via ocular tonometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expanded Access Protocol - Blinatumomab in Pediatric & Adolescent Subjects With Relapsed/Refractory B-precursor ALL
Status: NO_LONGER_AVAILABLE
Conditions: Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab|OTHER: Extension of LTFU as per ProtocolAmendment7 7Jun18
Study Type: EXPANDED_ACCESS
Clinical trial: A Study of Pegasys (Peginterferon Alfa-2a) Administered Alone or in Combination With Copegus (Ribavirin) in Patients With Chronic Hepatitis C Who Have Participated in Previous Pegasys Trials
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers
Status: COMPLETED
Conditions: Compartment Syndrome of Leg|Healthy
Interventions: DRUG: Mepivacaine Injection|DRUG: Mepivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of 12-months of Denosumab on Bone Density in Prevalent Kidney Transplant Recipients
Status: TERMINATED
Conditions: Osteoporosis|Renal Osteodystrophy|Kidney Transplant; Complications
Interventions: DRUG: Denosumab Inj 60 mg/ml|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Training and Counseling Program for Overactive Bladder Treatment
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: BEHAVIORAL: a counseling and training program that consisted of a 45-minute presentation based on Pender's Health Promotion Model. Within the scope of the counseling and training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depression
Interventions: BEHAVIORAL: HOPES-I
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Potassium Supplementation to Reduce Blood Pressure
Status: COMPLETED
Conditions: Prehypertension
Interventions: DIETARY_SUPPLEMENT: High potassium water|DIETARY_SUPPLEMENT: Control low potassium water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Acalabrutinib|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-masked, Placebo-controlled Safety, Tolerability, and Efficacy Study of VRDN-001, a Humanized Monoclonal Antibody Directed Against the IGF-1 Receptor, in Participants With Chronic Thyroid Eye Disease (TED)
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: VRDN-001 10 mg/kg Drug:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405
Status: COMPLETED
Conditions: Hypertension(HTN)
Interventions: DRUG: HGP0904|DRUG: HGP0608|DRUG: HGP1405
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Diagnostic Performance of MRI±Biopsy to Optimize Resection of Ductal Carcinoma In Situ (DCIS) Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: MRI±biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation MRI - Propofol Versus Propofol-Ketamin in Children
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Propofol|DRUG: Ketamine-Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Pharmacokinetic Study Comparing MB02 And US And EU Avastin® In Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MB02|DRUG: US licenced Avastin®|DRUG: EU approved Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance
Status: NOT_YET_RECRUITING
Conditions: Hypothyroidism|Insulin Resistance
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Immunogenicity and Safety of sIPV in a '1+2' Sequential Schedule With bOPV in Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: sIPV-bOPV-bOPV vaccination schedule|BIOLOGICAL: wIPV-bOPV-bOPV vaccination schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessing Jet Administration of pBI-11 for the Treatment of Patients With HPV16/18+
Status: NOT_YET_RECRUITING
Conditions: HPV Infection
Interventions: DRUG: pBI-11
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dr.Reddy's Fexofenadine Hydrochloride 180 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0216, Combination Chemotherapy and RT in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability in Individuals With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: BEHAVIORAL: Duchenne Muscular Dystrophy group with Deflazacort|BEHAVIORAL: Duchenne Muscular Dystrophy group with Prednisone/Predisolone|BEHAVIORAL: Duchenne Muscular Dystrophy group without Corticosteroids therapy|BEHAVIORAL: Control Group Typically Developing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars
Status: TERMINATED
Conditions: Dental Pain
Interventions: DRUG: NTC-510 capsules|DRUG: Placebo Capsules|DRUG: NTC-510A Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin in Management of Newly Diagnosed ITP
Status: UNKNOWN
Conditions: Immune Thrombocytopenia|Purpura, Thrombocytopenic
Interventions: DRUG: Atorvastatin 20mg|DRUG: Atorvastatin 10mg|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women
Status: COMPLETED
Conditions: Obesity, Maternal|Post Partum Hemorrhage
Interventions: DRUG: Carbetocin 100 Microgram/mL Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of Valganciclovir Hydrochloride Tablets 450 mg Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Valganciclovir Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adverse Events in Pharmaceutical Bioequivalence Study of Two Formulations of Metformine Hydrochloride 500 mg
Status: UNKNOWN
Conditions: Nutritional and Metabolic Diseases
Interventions: DRUG: Metformin|DRUG: Glifage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL
Status: COMPLETED
Conditions: Relapsed or Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: CYC065|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Mesenchymal Stem Cells and Mononuclear Cells Infusion in Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 1 Diabetes Mellitus
Interventions: BIOLOGICAL: Umbilical mesenchymal stem cell (UC-MSCs) infusion|DRUG: traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study, 2nd Wave
Status: RECRUITING
Conditions: Coronary Disease|Myocardial Infarction|Heart Failure|Arrhythmias, Cardiac|Peripheral Artery Disease|Stroke|Ischemic Attack, Transient|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Pulmonary Disease, Chronic Obstructive|Asthma|Renal Insufficiency|Depressive Disorder|Anxiety Disorders|Schizophrenia|Peripheral Nervous System Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anhydrous Enol-Oxaloacetate (AEO) on Improving Fatigue in Post-COVID-19 Survivors
Status: UNKNOWN
Conditions: Treatment of Fatigue After Resolution of COVID-19 Infection
Interventions: DIETARY_SUPPLEMENT: Oxaloacetate Medical Food/Dietary Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cricoid Pressure Versus Paratracheal Pressure
Status: UNKNOWN
Conditions: Cricoid Pressure During Tracheal Intubation
Interventions: PROCEDURE: cricoid pressure|PROCEDURE: left paratracheal pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Does Chemotherapy Train the Mutation of the Pig-A Gene? (PIGA)
Status: UNKNOWN
Conditions: Breast Cancer Female
Interventions: BIOLOGICAL: Blood collection and Micronuclei assay on binucleate lymphocytes in culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Investigation of the Vanguard™ Complete Knee System
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Traumatic Arthritis|Rheumatoid Arthritis|Lower Limb Deformity|Complications, Arthroplasty
Interventions: DEVICE: Vanguard™ Complete Knee System|DEVICE: Vanguard™ Patient-Specific Femur
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Dose Effect of Oxytocin on Males With High or Low Trait Anxiety
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rituximab in Auto-Immune Hemolytic Anemia
Status: COMPLETED
Conditions: Warm Autoimmune Hemolytic Anemia
Interventions: DRUG: rituximab (Mabthera®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T for Autoimmune Hemolytic Anemia Patients Who Have Failed Three or More Lines of Therapy
Status: RECRUITING
Conditions: Autoimmune Hemolytic Anemia|CD19 CAR-T Cell Infusion
Interventions: BIOLOGICAL: ThisCART19A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CARRA Registry
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis|Systemic Lupus Erythematosus|Mixed Connective Tissue Disease|Juvenile Ankylosing Spondylitis|Juvenile Dermatomyositis|Localized Scleroderma|Systemic Sclerosis|Vasculitis|Sarcoid|Fibromyalgia, Primary|Auto-inflammatory Disease|Idiopathic Uveitis Idiopathic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Insulin: A Comparison With Subcutaneous Regular Human Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Oral insulin|DRUG: regular human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban in Patients With Atrial Fibrillation and Coronary Artery Disease Undergoing Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: rivaroxaban and ticagrel therapy|DRUG: triple antithrombotic regimen with warfarin, asipirin and clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hand-assisted Laparoscopic Surgery (HALS) for Myomectomy
Status: TERMINATED
Conditions: Uterine Myomas
Interventions: PROCEDURE: HALS|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bacillus Subtilis BS50 Supplementation on Gastrointestinal Symptoms in Healthy Adults
Status: COMPLETED
Conditions: Gastrointestinal Health|Immune Health|Cardiovascular Health|Digestive Health
Interventions: DIETARY_SUPPLEMENT: Bacillus subtilis BS50 spore preparation|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Effectiveness of Duloxetine and Desipramine in Patients With Chronic Pain: A Pragmatic Trial Using Point of Care Randomization
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DRUG: Duloxetine|DRUG: Desipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Antimycobacterial Therapy in Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis
Interventions: DRUG: Antibiotic Regimen|DRUG: Placebo Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Two Electroacupuncture Waveforms for Different Severity Groups of Bell Palsy
Status: NOT_YET_RECRUITING
Conditions: Bell Palsy
Interventions: OTHER: electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Objective Markers of Pain Perception in Pediatric Emergency
Status: COMPLETED
Conditions: Suffering, Physical
Interventions: DEVICE: electroencephalography helmet|DEVICE: dermal electrode|DEVICE: blood pressure sensors|DEVICE: Pupillometry glasses|DEVICE: Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Safety Study of Chronocort in the Treatment of Participants With Congenital Adrenal Hyperplasia
Status: ENROLLING_BY_INVITATION
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Chronocort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ectopy Triggering Ganglionated Plexus Ablation to Prevent Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation|PROCEDURE: Ganglionated plexus ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)
Status: RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: NVL-330
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Long-term Effect of Pep2Dia® on Glucose Homeostasis in Prediabetic Subjects
Status: COMPLETED
Conditions: Prediabetic State
Interventions: DIETARY_SUPPLEMENT: Pep2dia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Penile Traction Therapy Using a Novel Device
Status: COMPLETED
Conditions: Penile Diseases
Interventions: DEVICE: RestoreX PTT - randomized and open label|DEVICE: RestoreX PTT - open label phase only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT II)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm|Recurrent Malignant Neoplasm
Interventions: DRUG: Targeted Therapy Based on Molecular Profiling|DRUG: Standard-of-Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Podiatry Led MDT Intervention to Reduce the Burden of Foot Disease in Patients With End Stage Kidney Failure
Status: UNKNOWN
Conditions: Diabetes Mellitus|Endstage Renal Disease
Interventions: PROCEDURE: Podiatry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reintegrating Children Living at Landfills in Burundi Into Society by Means of a Comprehensive Family Program Addressing Maltreatment and Mental Health Symptoms
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Aggressive Behaviour|Parental Maltreatment|Days Spent at the Landfill
Interventions: BEHAVIORAL: Comprehensive family intervention including individual sessions of FORNET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laterally Closed Tunnel VS Tunneling Technique in Recession Type 2
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: Group A (Lateral closed tunnel subepithelial CT graft)|PROCEDURE: Group B (Tunnel procedure with subepithelial CT graft)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial Bacteria Treatment for Autism
Status: COMPLETED
Conditions: Gastrointestinal Problems|Autism Spectrum Disorders
Interventions: DRUG: oral Vancomycin|DRUG: MoviPrep|DRUG: Prilosec|BIOLOGICAL: human fecal material; processed, frozen administered orally|BIOLOGICAL: human fecal material; processed, frozen; administered orally and rectally
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan and Stem Cell Transplant Before Total-Body Irradiation and Donor Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: melphalan|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation|PROCEDURE: peripheral blood stem cell transplantation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sucrosomial Iron in Patients With Celiac Disease and IDA
Status: UNKNOWN
Conditions: Celiac Disease|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: sucrosomial iron|DRUG: Sulphate iron
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Associations of Combinations of Single-nucleotide Polymorphisms in Women With Premature Ovarian Failure
Status: COMPLETED
Conditions: Primary Ovarian Insufficiency|Cardiovascular Diseases|Menopause, Premature|Coronary Disease|Pulmonary Embolism|Arrhythmias, Cardiac|Polymorphism, Single Nucleotide
Interventions: BEHAVIORAL: Taking a person's venous blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impacting Children's Physical and Mental Health Through Kinesiology Support in Clinical Care
Status: COMPLETED
Conditions: Congenital Heart Defect|Chronic Pain|Concussion Post Syndrome|Cerebral Palsy|Neuromuscular Diseases|Physical Disability
Interventions: BEHAVIORAL: Kinesiology Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Loop Resectoscope in Treating Patients With Bladder Cancer or Benign Prostatic Hyperplasia Who Are Undergoing Transurethral Resection
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: PROCEDURE: biopsy|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Literacy Education in Adults (HELP-e-Pulse)
Status: NOT_YET_RECRUITING
Conditions: Health Literacy
Interventions: OTHER: Health education:Interactive group training|OTHER: Health education: Individually training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Facial Skin Clinical and Microbial Profiling From Oral Probiotic Supplementation
Status: COMPLETED
Conditions: Healthy|Skin Manifestations
Interventions: DIETARY_SUPPLEMENT: Probiotic with niacin and berry extract|DIETARY_SUPPLEMENT: Probiotic without niacin and berry extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Examining the Use of a Novel Immersive Motion Tracking Upper Extremity Exercise Program for Acute Hospitalized Patients
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplant|Liver Transplant
Interventions: DEVICE: MoveMend Health
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Parent Feedback Intervention Targeting Student Transitions and Alcohol Related Trajectories (+) Efficacy Study
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol Problem Drinking|Parenting
Interventions: BEHAVIORAL: FITSTART+ PBI|BEHAVIORAL: General Parenting Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION