pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmacokinetics, Efficacy, and Safety Study of RI-002 (IGIV) in Subjects With Primary Immunodeficiency Diseases (PIDD)
Status: COMPLETED
Conditions: Primary Immune Deficiency Disorder
Interventions: BIOLOGICAL: RI-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Dexamethasone|OTHER: Placebo Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Strength and Mobility and Corresponding CNS Plasticity in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: specifically design 6 month resistance training program|BEHAVIORAL: 6 months weight resistance and balance program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiotherapy Versus Radiotherapy Plus Chemotherapy in Early Stage Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: Cyclophosphamide|RADIATION: Radiotherapy|DRUG: Vincristine|DRUG: Prednisolone|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
Status: RECRUITING
Conditions: Adenocarcinoma|Stomach Neoplasm|Gastroesophageal-junction Cancer|Oligometastatic Disease|Metastatic Cancer|Metastatic Gastric Cancer|Adenocarcinoma of the Stomach|Gastroesophageal Junction Adenocarcinoma|Metastatic Adenocarcinoma
Interventions: RADIATION: Radiotherapy targeted to the primary lesion|RADIATION: Radiotherapy targeted to the metastatic lesions|BIOLOGICAL: Anti-PD-1 monoclonal antibody|BIOLOGICAL: Trastuzumab|DRUG: Chemotherapy|PROCEDURE: R0 total/subtotal gastrectomy with D2 lymphadenectomy|PROCEDURE: Metastasectomy|PROCEDURE: Local ablative therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma
Status: COMPLETED
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: capecitabine-irinotecan|DRUG: capecitabine+irinotecan (1st line)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-Based Symptom Monitoring and Self-Management Portal (YES) for Adolescent and Young Adult Breast Cancer Survivors
Status: RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Best Practice|OTHER: Internet-Based Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment With Nelfinavir or Efavirenz of HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Keyhole-Limpet Hemocyanin|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic/Pharmacodynamic Study of Eurartesim Dispersible Formulation in Infants With P.Falciparum Malaria
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: DRUG: Eurartesim dispersible oral tablet|DRUG: eurartesim film coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization
Status: TERMINATED
Conditions: Respiratory Failure|COVID-19
Interventions: BEHAVIORAL: Intermittent prone positioning instructions|BEHAVIORAL: Usual care positioning with no instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Sequelae Caused by Severe Brain Injury With Autologous Adipose-derived Mesenchymal Stem Cells
Status: COMPLETED
Conditions: The Sequelae Caused by Severe Brain Injury
Interventions: BIOLOGICAL: autologous adipose-derived mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver Cell Transplant for Phenylketonuria
Status: TERMINATED
Conditions: Phenylketonuria
Interventions: RADIATION: Preparative Radiation Therapy|PROCEDURE: Hepatocyte Transplant|DRUG: Immunosuppression|OTHER: Liver Evaluation|BEHAVIORAL: Neuro-psychological Assessment|DIAGNOSTIC_TEST: Whole body Phe oxidation testing|PROCEDURE: Liver Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Fasting for Ambulatory Cataract Surgery: The PRACTICE Study
Status: UNKNOWN
Conditions: Cataract Extraction|Fasting|Aspiration Pneumonitis
Interventions: BEHAVIORAL: Assistant-encouraged fasting up to ASA/CAS guideline limits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TMC435-TiDP16-C112 - Interaction Trial With Antidepressants
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: TMC435|DRUG: Escitalopram|DRUG: TMC435 + Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Assessment of QFR in STEMI-II
Status: UNKNOWN
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: Computation of quantitative flow ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of REGN668 Administered Subcutaneously to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: REGN668: Injection Rate 1|DRUG: REGN668: Injection Rate 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing the Safety and Efficacy of Insulin Degludec and Insulin Glargine, With or Without OADs in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Dasotraline in Children 6 to 12 Years Old With Attention-Deficit Hyperactivity Disorder (ADHD) in a Simulated Classroom Setting.
Status: COMPLETED
Conditions: Attention-Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: dasotraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Carboplatin and Gemcitabine in Women With Recurrent, Platinum-Sensitive Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Vorinostat|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Effects of a Topical Amino Acid Moisturizing Cream and Desonide in Atopic Dermatitis
Status: UNKNOWN
Conditions: Dermatitis, Atopic|Eczema
Interventions: DRUG: Desonide Cream|OTHER: Amino Acid Moisturizing Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: SHX-001 Active low dose|DRUG: Placebo|DRUG: SHX-001 Active High dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Intake of Caffeinated Beverages in Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: Caffeine enhanced energy drink|OTHER: Glucose drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ALL-SCT BFM International- HSCT in Children and Adolescents With ALL
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute, Childhood;
Interventions: DRUG: VP16|RADIATION: TBI|DRUG: VP16, ATG|RADIATION: TBI|DRUG: Fludarabine, OKT3, Treosulfan, Thiotepa|DRUG: VP16, ATG|RADIATION: TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence on Erythropoetin-level by Xenon
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: Xenon pro Anaesthesia 100 % (V/V)|DRUG: Aer medicinalis Linde 100%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plinabulin vs. Pegfilgrastim in Patients With Solid Tumors Receiving Docetaxel Myelosuppressive Chemotherapy Phase 2
Status: COMPLETED
Conditions: Chemotherapy-induced Neutropenia
Interventions: DRUG: Plinabulin|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Surfactant Delivery Via Laryngeal Mask Airway (LMA) Versus Endotracheal Intubation
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Newborn
Interventions: DEVICE: Endotracheal tube insertion|DEVICE: Laryngeal mask airway insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Pharmacokinetics and Tolerability of Bimatoprost Applied to the Scalp of Male Patients With Androgenetic Alopecia
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: Bimatoprost 1% Formulation A|DRUG: Bimatoprost 1% Formulation B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Imatinib Mesylate Combined With Rectal-sparing Surgery in Patients With c-KIT Gene-mutant Rectal GIST
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Stromal Tumor of Rectum
Interventions: DRUG: Imatinib Mesylate|PROCEDURE: Local resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD20 Radioimmunotherapy Before Chemotherapy and Stem Cell Transplant in Treating Patients With High-Risk B-Cell Malignancies
Status: TERMINATED
Conditions: Burkitt Lymphoma|CD20-Positive Neoplastic Cells Present|Diffuse Large B-Cell Lymphoma|Indolent Non-Hodgkin Lymphoma|Mantle Cell Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Refractory Mature B-Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Anti-CD20 B9E9 scFv-Streptavidin Fusion Protein|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Clearing Agent|DRUG: Cytarabine|DRUG: Etoposide|RADIATION: Indium In 111-DOTA-Biotin|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|RADIATION: Yttrium Y 90-DOTA-Biotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tenalisib (RP6530) in Combination With Romidepsin in Patients With Relapsed/Refractory T-cell Lymphoma
Status: COMPLETED
Conditions: T Cell Lymphoma
Interventions: DRUG: Tenalisib|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bed and Breakfast (B&B) Study
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Low GI Breakfast|OTHER: High GI Breakfast|OTHER: Low GI Dinner|OTHER: High GI Dinner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Lysozyme on Acute Exacerbation of Chronic Obstructive Pulmonary Disease : A Randomised Placebo-Controlled Study
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Lysozyme hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pulp Response to Castor Oil
Status: COMPLETED
Conditions: Pulp Response to Castor Oil
Interventions: DRUG: Castor oil|DRUG: Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Differentiated Thyroid Gland Carcinoma|Follicular Variant Thyroid Gland Papillary Carcinoma|Poorly Differentiated Thyroid Gland Carcinoma|Refractory Differentiated Thyroid Gland Carcinoma|Refractory Thyroid Gland Carcinoma|Tall Cell Variant Thyroid Gland Papillary Carcinoma|Thyroid Gland Follicular Carcinoma|Thyroid Gland Oncocytic Carcinoma|Thyroid Gland Papillary Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comfort and Adherence of Rivelin® Plain Patches in Vulva Lichen Sclerosus Patients
Status: COMPLETED
Conditions: Vulvar Lichen Sclerosus
Interventions: DEVICE: Rivelin® plain patches
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I-II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation and Pharmacokinetics of PD-0332991 in Patients Suffering Metastatic Melanoma
Status: UNKNOWN
Conditions: Melanoma BRAF V600E/K Mutated|CDNKN2A Loss Defined
Interventions: DRUG: PD- 0332991
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Title: Evaluation of a Novel PET Radioligand for Phosphodiesterase-4D (PDE4D)
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: [C-11]T-1650|DRUG: BPN14770
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Aortic Valve Replacement on Myocardial T1 Values in Severe Aortic Valve Stenosis
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Replacement|Myocardial Fibrosis|Cardiac Magnetic Resonance|T1 Mapping
Interventions: PROCEDURE: Aortic valve replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Newer Breast MRI Sequences for the Evaluation of Breast Cancer -FIESTA, Vibrant-DE and IDEAL: Feasibility Evaluation
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: new software sequences, FIESTA and Vibrant-DE and IDEAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment for Growth Failure in Patients With X-Linked Severe Combined Immunodeficiency: Phase 2 Study of Insulin-Like Growth Factor-1
Status: TERMINATED
Conditions: Growth Failure|X-linked Severe Combined Immunodeficiency (XSCID)|Growth Hormone Resistence
Interventions: DRUG: Increlex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HR19042 Capsules in the Treatment of Autoimmune Hepatitis.
Status: RECRUITING
Conditions: Autoimmune Hepatitis
Interventions: DRUG: HR19042 Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Evaluate the Safety and Efficacy of Ganciclovir (Dihydroxypropoxymethyl Guanine [DHPG]) Treatment of Symptomatic Central Nervous System (CNS) Congenital Cytomegalovirus (CMV) Infections.
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Study to Evaluate the Safety and Efficacy of Micafungin Against Fungal Infections Caused by Candida Spp or Aspergillus Spp
Status: TERMINATED
Conditions: Aspergillosis|Candidiasis
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor
Status: COMPLETED
Conditions: Choroidal Neovascularization|Punctate Inner Choroidopathy
Interventions: DRUG: Bevacizumab Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Roxadustat in the Treatment of Anemia in Chronic Kidney Disease Patients Not Requiring Dialysis
Status: COMPLETED
Conditions: Anemia in Chronic Kidney Disease in Non-dialysis Patients
Interventions: DRUG: Roxadustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation Of The Effect Of Proprioceptive Neuromuscular Fasilitation Tecniques in Scapular Dyskinesis
Status: COMPLETED
Conditions: Scapular Dyskinesis
Interventions: OTHER: Exercise, proprioceptive neuromuscular fasilition (PNF) techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Reorganization in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Brain Fitness & Brain Training- Posit Science|BEHAVIORAL: Facial Affect Training- FAT|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Intervention Study Using HMOs to Improve IBS Symptoms
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Human milk oligosaccharide|DIETARY_SUPPLEMENT: Maltodextrin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Adding Pain Relievers to Local Anesthesia Before Preforming Drainage in Peritonsillar Abscess
Status: UNKNOWN
Conditions: Peritonsillar Abscess
Interventions: DRUG: dypiron, tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Nivolumab in Leptomeningeal Metastases
Status: COMPLETED
Conditions: Leptomeningeal Carcinomatosis
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperemic Efficacy of IV Adenosine in HFrEF
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction|Coronary Artery Disease
Interventions: OTHER: Maximal hyperemia with adenosine followed by nicorandil|OTHER: Maximal hyperemia with nicorandil followed by adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Pantoprazole Trial in Patients With Symptoms of Chronic Acid Peptic Complaints (BY1023/VMG-708)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)|Peptic Ulcers
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Triphala" - A New Herbal Mouthwash in Gingivitis
Status: COMPLETED
Conditions: Gingivitis
Interventions: BEHAVIORAL: Triphala mouthwash|BEHAVIORAL: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of a Fiber Supplement for Weight Loss
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Glucomannan|DIETARY_SUPPLEMENT: Inert microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form
Status: RECRUITING
Conditions: Food Protein Induced Enterocolitis Syndrome (FPIES)
Interventions: DIAGNOSTIC_TEST: allergy test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia (AML) or Chronic Myelomonocytic Leukemia (CMML) (MK-0482-002)
Status: TERMINATED
Conditions: Relapsed or Refractory Acute Myeloid Leukemia|Relapsed or Refractory Chronic Myelomonocytic Leukemia
Interventions: BIOLOGICAL: MK-0482
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Len/Dex/DLI in Relapsed Multiple Myeloma After Allogeneic Stem Cell Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Hematologic Malignancy|Multiple Myeloma
Interventions: DRUG: Lenalidomide-Dexamethasone-DLI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBT for Social Anxiety Disorder Delivered by School Counselors
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Skills for Academic and Social Success|BEHAVIORAL: Skills for Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin and Docetaxel in Treating Women With Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Filgrastim|DRUG: Docetaxel|DRUG: Doxorubicin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipodystrophy and Fat Metabolism During Exercise
Status: WITHDRAWN
Conditions: Healthy|Lipodystrophy, Familial Partial
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: High-carbohdyrate breakfast|BEHAVIORAL: 60-minutes of steady state exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Therapy for Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: RADIATION: Proton Radiation Plan|RADIATION: Conventional Photon Radiation Plan|RADIATION: Intensity Modulated Radiation Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontally Accelerated Osteogenic Orthodontics With BMP2
Status: COMPLETED
Conditions: Malocclusion
Interventions: DRUG: RhBMP-2 Protein, Recombinant|OTHER: Conventional Corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: (ARTEMIS-IPF) Randomized, Placebo-Controlled Study to Evaluate Safety and Effectiveness of Ambrisentan in IPF
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Ambrisentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Affect Treatment (PAT) to Target Reward Mechanisms in Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Anorexia
Interventions: BEHAVIORAL: Positive Affect Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smart Phone-Based Application for Evaluation and Rehabilitation of HindFoot Pain
Status: UNKNOWN
Conditions: Achilles Tendinopathy|Plantar Fascitis|Feet Pes Cavus|Feet Pes Planus (Flatfoot)|Foot Diseases
Interventions: DIAGNOSTIC_TEST: smart phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating Baby Behavior and Family Technology Use Study
Status: RECRUITING
Conditions: Mobile Phone Use|Mother-Infant Interaction|Infant Development|Self-Regulation, Emotion|Self-Regulation
Interventions: BEHAVIORAL: Technology Use during Feeding Conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Doravirine (MK-1439) on Methadone Pharmacokinetics in Methadone-Maintained Participants (MK-1439-045)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: Methadone|DRUG: Doravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture Treatment for Breast Cancer-associated Insomnia
Status: RECRUITING
Conditions: Breast Neoplasms|Insomnia
Interventions: DEVICE: Acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Healthy Vietnamese Women According to a 0, 1, 6 Month Schedule
Status: UNKNOWN
Conditions: Human Papillomavirus (HPV) Vaccine
Interventions: BIOLOGICAL: HPV-16/18 L1 VLP AS04 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Senl-T7 CAR T Cells in the Treatment of Relapsed and Refractory CD7+ Acute T-ALL/T-LBL
Status: RECRUITING
Conditions: T-cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions: BIOLOGICAL: Senl-T7
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Inhaled Nitric Oxide in Moderate-to-Severe Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nitric Oxide Generation and Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of Motor Seizure Duration of Ketofol and Propofol for Electroconvulsive Therapy
Status: COMPLETED
Conditions: Electroconvulsive Therapy
Interventions: DRUG: ketofol vs propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OmegaChild - Omega-3 Supplementation to Children Previously Treated for Cancer
Status: COMPLETED
Conditions: Pediatric Cancer
Interventions: DIETARY_SUPPLEMENT: Omega-3 enriched fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vibration Stimuli in Stroke Patients With Contraversive Pusher Syndrome
Status: WITHDRAWN
Conditions: Stroke
Interventions: DEVICE: Vibration stimuli to neck muscles|DEVICE: Vibration stimuli to hand|BEHAVIORAL: conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Acceptability of Q GRFT Nasal Spray for COVID-19 Prophylaxis
Status: COMPLETED
Conditions: COVID-19|Pharmacokinetics|Safety
Interventions: DRUG: Q-Griffithsin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tislelizumab Combined With Anlotinib and 2-cycles Irinotecan as Second Line Treatment of SCLC
Status: UNKNOWN
Conditions: Small Cell Lung Cancer (SCLC)
Interventions: DRUG: Anlotinib Tislelizumab Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duloxetine in Osteoarthritis (OA) Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Duloxetine|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL)
Status: UNKNOWN
Conditions: Toxoplasmosis|Toxoplasma Infections|Toxoplasmosis, Congenital|Toxoplasmosis Recurrent
Interventions: DIAGNOSTIC_TEST: anti-Toxoplasma gondii IgG and IgM dosage|DIAGNOSTIC_TEST: cellular test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupressure for Pain and Opioid Use Among Breast Cancer Patients
Status: TERMINATED
Conditions: Breast Cancer|Fatigue|Chronic Pain
Interventions: OTHER: Self-administered acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 4 Two Dose Level Study of Naglazyme(TM) (Galsulfase) in Infants With MPS VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis VI|Maroteaux-Lamy Syndrome
Interventions: DRUG: Naglazyme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcome After Needle vs Blade Achilles Tenotomy in Clubfoot
Status: COMPLETED
Conditions: Club Foot|Achilles Tendon Surgery
Interventions: PROCEDURE: Achilles tendon tenotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Resiliency in Veteran Families With Young Children
Status: COMPLETED
Conditions: Stress, Psychological|Stress Disorders, Traumatic|Regulation, Self|Behavior, Child|Emotional Stress|Trauma, Psychological|Anxiety|Depression
Interventions: BEHAVIORAL: FOCUS-EC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: TCM for Coal Worker's Pneumoconiosis
Status: UNKNOWN
Conditions: Coal Worker's Pneumoconiosis
Interventions: DRUG: Chinese medicine compound combined with symptomatic treatments|DRUG: Chinese medicine compound placebo combined with symptomatic treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Lopinavir/ Ritonavir to Improve the Health of People With COVID-19: "The Hope Coalition - 1"
Status: UNKNOWN
Conditions: COVID-19|Coronavirus Infection|Virus Disease|Acute Respiratory Infection|SARS-CoV Infection
Interventions: DRUG: Hydroxychloroquine Sulfate Tablets|DRUG: Lopinavir/ Ritonavir Oral Tablet|DRUG: Hydroxychloroquine Sulfate Tablets plus Lopinavir/ Ritonavir Oral Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study in Subjects to Follow the Progression of Stargardt Disease Type 1 (STGD1) Caused by Bi-Allelic Autosomal Recessive Mutations in the ABCA4 Gene
Status: RECRUITING
Conditions: Stargardt|Stargardt's Disease|Stargardt Disease|STGD1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of add-on Sarcosine in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Sarcosine and SSRI|DRUG: Placebo and SSRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986416 With and Without Nivolumab in Select Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: BMS-986416|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neostigmine for Ultrasound Guided Supraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: ultrasound- guided supraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: BREAST-10: Three-weekly Versus Weekly First-line Chemotherapy for Metastatic or Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: docetaxel|DRUG: epirubicin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a French Version of the DHEQ
Status: RECRUITING
Conditions: Dentin Hypersensitivity|Quality of Life
Interventions: DIAGNOSTIC_TEST: Schiff Test|OTHER: GOHAI questionnaire|OTHER: OHIP questionnaire|OTHER: DHEQ fr questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Intraductal Radiofrequency Ablation in Combination With Metallic Biliary Stenting in Advanced Hilar Cholangiocarcinoma
Status: COMPLETED
Conditions: Hilar Cholangiocarcinoma|Biliary Obstruction
Interventions: DEVICE: ELRA endoluminal radiofrequency ablation electrode (Taewoong, Seoul, Korea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BAY43-9006 - Phase II in Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Response to Chest Physiotherapy in Children With Acute Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: OTHER: Nebulization of hypertonic saline|OTHER: Prolonged slow expiration technique (PSE)|OTHER: Patient coughing Provocation (TP)|OTHER: inspiratory maneuver to rhinopharyngeal cleaning DRR|OTHER: Aspiration of secretions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets (Administered Three Times Daily)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trazodone HCl|DRUG: Trazodone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fondaparinux as an Anticoagulant in Haemofiltration in Patients With Acute Kidney Failure.
Status: TERMINATED
Conditions: Renal Failure
Interventions: DRUG: Fondaparinux Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet-Induced Variability in Appetite (DIVA)
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Alternate Day Fasting|BEHAVIORAL: Continuous dietary restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Tamsulosin in Treatment of (10-15 mm) Lower Ureteric Stones in Adults With Non-emergent Symptoms
Status: UNKNOWN
Conditions: Ureteric Stone
Interventions: DRUG: Tamsulosin.|DRUG: Placebo.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validity and Reliability of Indonesian Translated Ages and Stages Questionnaires - Third Edition (ASQ-3) as a Screening Tool for Developmental Delay in 1-12 Months Old Children
Status: COMPLETED
Conditions: Developmental Delay|Child Development|Child Development Disorder|Global Developmental Delay|Infant Development|Motor Delay|Speech Delay|Communication Disorders|Development Delay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combining tDCS and CILT in Non-fluent Aphasia
Status: COMPLETED
Conditions: Aphasia|Non-fluent Aphasia|Stroke|Brain Injuries
Interventions: DEVICE: tDCS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dapagliflozin on the Short-term Prognosis of Patients With Acute Myocardial Infarction
Status: RECRUITING
Conditions: Myocardial Infarction|Diabete Type 2|Glucose Intolerance
Interventions: DRUG: Dapagliflozin 10mg/Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Description of the Ability to Learn How to Handle Inhaler Devices in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Seretide® Diskus® 500/550 μg|DRUG: Ultibro® Breezhaler® 110/50 μg|DRUG: Spiriva® Respimat® 2,5 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ravicti low dose|DRUG: Ravicti high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of Valacyclovir Hydrochloride ( 256U87 ) Versus Acyclovir in the Treatment of Recurrent Anogenital Herpes Infections in HIV Infected Patients
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Valacyclovir hydrochloride|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prehabilitation Plus ERAS Versus ERAS in Gynecologic Oncology: a Randomized Clinical Trial
Status: RECRUITING
Conditions: Gynecologic Cancer|Enhanced Recovery After Surgery
Interventions: OTHER: Prehabilitation Program + Enhanced Recovery After Surgery|OTHER: Enhanced Recovery After Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fesoterodine on Urgency Episodes in Parkinson's Disease Population
Status: TERMINATED
Conditions: Urinary Bladder, Overactive|Parkinson Disease
Interventions: DRUG: Fesoterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Accessorized Pre-Filled Syringe to Autoinjector Pharmacokinetic Bridging Study in Anifrolumab
Status: COMPLETED
Conditions: Healthy Participants Study
Interventions: DRUG: Anifrolumab|DEVICE: Autoinjector|DEVICE: Accessorized Pre-Filled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Microbial Ecosystem Therapeutic-2 (MET-2) in Patients With Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: MET-2|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olopatadine 0.2% for the Treatment of Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine Hydrochloride Ophthalmic Solution, 0.2%|DRUG: Olopatadine Hydrochloride Ophthalmic Solution Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl
Status: COMPLETED
Conditions: Acute Pain|Trauma|Hypovolemia
Interventions: DRUG: Methoxyflurane (M)|DRUG: Fentanyl (F1)|DRUG: Fentanyl (F2)|DRUG: NaCl (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy
Status: TERMINATED
Conditions: Recurrent Vestibulopathy
Interventions: DRUG: Renexin (cilostazol 100mg + gingko biloba extract 80 mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Adult
Interventions: DRUG: Ertugliflozin 2 mg single dose|DRUG: Ertugliflozin 2 mg split into twice daily|DRUG: Ertugliflozin 4 mg single dose|DRUG: Ertugliflozin 4 mg split into twice daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Use of Botulinum Toxin A in Two-Stage Tissue Expander/ Implant Breast Reconstruction
Status: UNKNOWN
Conditions: Breast Neoplasms|Neoplasms by Site|Neoplasms|Breast Diseases|Skin Diseases
Interventions: DRUG: Botulinum Toxin-A|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Fluid Rapid Influenza and BinaxNOW Influenza A & B
Status: SUSPENDED
Conditions: Influenza
Interventions: DEVICE: fluID Rapid Influenza Test|DEVICE: BinaxNOW® Influenza A & B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Intravenous Administered Iron in Non-anemic Iron Deficient Patients With Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Iron-deficiency|Colorectal Cancer
Interventions: DRUG: Iron(III)isomaltoside|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ease of Use and Acceptability of Intranasal and Injectable Glucagon Among Providers Administering it to Children or Adolescents With Type 1 Diabetes (BETTER-ING)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hypoglycemia
Interventions: BEHAVIORAL: Videos|BEHAVIORAL: Simulation|BEHAVIORAL: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics
Status: RECRUITING
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT