pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Comparison of Low Thoracic Paravertebral Block Versus Peritubal Infiltration
Status: COMPLETED
Conditions: Percutaneous Nephrolithotomy
Interventions: DRUG: Bupivacaine|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platysma Incision Cosmesis
Status: COMPLETED
Conditions: Wound Heal
Interventions: PROCEDURE: Anterior Cervical Decompression and Fusion|PROCEDURE: Vertical Platysma Incision|PROCEDURE: Transverse Platysma Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Trial: Xanthohumol Metabolism and Signature (XMaS) in Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Xanthohumol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid and Safe Sputum Suction Method Validation
Status: RECRUITING
Conditions: Sputum
Interventions: PROCEDURE: continuous negative pressure suction|PROCEDURE: Intermittent negative pressure sputum suction through oral pharyngeal airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: BEHAVIORAL: Carbohydrate-restricted, high-fat diet|BEHAVIORAL: Regular composition diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Marrow Derived Stem Cells for the Treatment of Rotator Cuff Tears
Status: WITHDRAWN
Conditions: Rotator Cuff Tear|Rotator Cuff Injury
Interventions: PROCEDURE: Arthroscopic rotator cuff repair with bone marrow aspirate concentrate|PROCEDURE: Arthroscopic rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
Status: RECRUITING
Conditions: Fecal Incontinence
Interventions: BIOLOGICAL: Bioengineered Internal Anal Sphincter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LVSP Based CRT vs. RVAP Based CRT
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Cardiac Resynchronization Therapy|Left Ventricular Septal Pacing|Right Ventricular Septal Pacing
Interventions: DEVICE: left ventricular septal pacing|DEVICE: right ventricular apical pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Autologous Erythrocytes Derived MPs Packaging MTX Peritoneal Perfusion to Treat Malignant Ascites
Status: UNKNOWN
Conditions: Malignant Ascites
Interventions: OTHER: Erythrocytes derived MPs containing MTX|DRUG: convention drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breakfast Consumption and Energy Balance in Active Adult Males
Status: COMPLETED
Conditions: Energy Intake|Substrate Utilization|Hormones|Satiety
Interventions: DIETARY_SUPPLEMENT: Maltodextrin supplement|DIETARY_SUPPLEMENT: Whey supplement|DIETARY_SUPPLEMENT: Water|DIETARY_SUPPLEMENT: Maltodextrin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients
Status: RECRUITING
Conditions: BK Viremia|Kidney Transplant Infection|Kidney Transplant Failure and Rejection
Interventions: DRUG: Immunosuppression reduction/modification + intravenous immunoglobulin|OTHER: Immunosuppression reduction/modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Skin Care Product for the Management of Acute Radiodermatitis
Status: COMPLETED
Conditions: Radiodermatitis; Acute|Radiation Dermatitis
Interventions: OTHER: Hydrating emollient for acute radiodermatitis|OTHER: Standard institutional skin care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on the Safety and Efficacy of Cryopreserved Platelets in Hypoproliferative Thrombocytopenic Patients
Status: COMPLETED
Conditions: Hypoproliferative Thrombocytopenia
Interventions: BIOLOGICAL: Control arm receiving normal (never before frozen) platelets as per current clinical practice|BIOLOGICAL: Treatment arm receiving cryopreserved platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal Ectasia
Status: RECRUITING
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: Riboflavin|DRUG: Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Status: NOT_YET_RECRUITING
Conditions: Hallux Valgus|Anesthesia
Interventions: DRUG: 0.25% ropivacaine|DRUG: 0.5% ropivacaine|DRUG: 1% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: combined thoracic segmental spinal epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Food Product for Management of Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes|Glucose Tolerance Impaired in Pregnancy|Glucose Tolerance Impaired|Pregnancy Related|Insulin Sensitivity/Resistance
Interventions: OTHER: Ready-to-eat wholegrain porridge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-SARS-CoV-2 Monoclonal Antibodies for Long COVID (COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID|Post-Acute Sequela of COVID-19|Post-Acute COVID-19
Interventions: DRUG: AER002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Electromyographic Activity & Glenohumeral Motion
Status: COMPLETED
Conditions: Orthopedic Disorder
Interventions: OTHER: glenohumeral mobilization-oscillation|OTHER: glenohumeral mobilization-sustained
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the SNOWDROP Intervention: Using a Clinical Decision Support System and Patient Portal for Falls Prevention Among Older Patients in Primary Care
Status: COMPLETED
Conditions: Fall|Fall Injury|Fall Patients|Accidental Fall|Deprescribing
Interventions: DEVICE: CDSS|DEVICE: Patient Portal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Nalmefene, Baclofen and Impulsivity in Subjects With Alcohol Use Disorder and Healthy Control Subjects
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Nalmefene|DRUG: Baclofen|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-Label, Randomized, 24-Week Study to Compare the Safety and Activity of Indinavir Sulfate, 800 Mg q 8 h Versus 1,200 Mg q 12 h in Combination With Zidovudine and 3TC
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Mavorixafor in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: WHIM Syndrome
Interventions: DRUG: Mavorixafor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
Status: RECRUITING
Conditions: Malocclusion|Misaligned Teeth
Interventions: DEVICE: Clear Aligners with Dental Monitoring|DEVICE: Clear Aligners
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study New Gel for Xerostomia
Status: UNKNOWN
Conditions: XEROSTOMIA
Interventions: DRUG: gel xerostomia|OTHER: gel placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-DOTA-Bombesin PET/MRI in Imaging Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Carcinoma
Interventions: DRUG: 68Ga-DOTA-Bombesin|PROCEDURE: Magnetic Resonance Imaging (MRI) scan|PROCEDURE: Positron Emission Tomography (PET) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CT 327 in the Treatment of Atopic Dermatitis
Status: TERMINATED
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: DRUG: placebo|DRUG: CT 327
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Placebo|DRUG: KAI-1678
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Nerve Problems|Diabetic Neuropathy|Diabetic Complications Neurological
Interventions: DRUG: Lidocaine 5% patch|DRUG: Capsaicin 8% Patch, Per 10 Square Centimeters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Hybrid Prototype Strategy (Electrostimulation of Lower Limb Muscles Associated With Voluntary Strengthening of the Upper Limbs) in Reconditioning to Effort in Patients With Chronic Paraplegia.
Status: COMPLETED
Conditions: Chronic Paraplegia
Interventions: OTHER: strengthening|OTHER: hybrid training programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Effectiveness of Gain- Versus Loss-framed Health Messages to Improve Oral Health Among Iranian Adolescents
Status: COMPLETED
Conditions: Health Behavior
Interventions: BEHAVIORAL: Framing (Gain-framed messages)|BEHAVIORAL: Framing (Loss-framed messages)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Profile of TNM005 in Healthy Adult Subjectsy
Status: RECRUITING
Conditions: Varicella
Interventions: DRUG: TNM005|DRUG: Placebo|DRUG: VariZIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Cabozantinib in Patients With Advanced, Low Proliferative NEN G3
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors|Neuroendocrine Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Combined With Irinotecan as Second-line in Patients With Metastatic Gastro-oesophageal Adenocarcinomas
Status: TERMINATED
Conditions: Adenocarcinoma of the Stomach|Adenocarcinoma of the Gastroesophageal Junction
Interventions: COMBINATION_PRODUCT: Regorafenib and Irinotecan|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systemic Exposure of Catechins From Veregen 15% Ointment in Patients With External Anogenital Warts and From Oral Intake of Green Tea Beverage in Healthy Volunteers
Status: COMPLETED
Conditions: Anogenital Warts
Interventions: DRUG: Veregen|OTHER: Green Tea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Adrenocortical Carcinoma|Brain and Central Nervous System Tumors|Head and Neck Cancer|Liver Cancer|Malignant Mesothelioma|Pheochromocytoma|Sarcoma
Interventions: DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lymphoedema and Nocturia/Nocturnal Polyuria After Pelvic LND for Urogenital Cancer
Status: RECRUITING
Conditions: Urogenital Cancer|Lower Limb Lymphedema|Nocturia|Nocturnal Polyuria
Interventions: OTHER: usual care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2)
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: aflibercept|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer
Status: RECRUITING
Conditions: Triple-negative Breast Cancer and HR+/HER2- BC
Interventions: DRUG: SKB264|DRUG: KL-A167
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Randomized, Open-Label Study of Guadecitabine vs Treatment Choice in Previously Treated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: guadecitabine|DRUG: Treatment Choice (TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of SGLT2 Inhibitor on Type 2 Diabetic Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Cardiac Surgery
Interventions: DRUG: Dapagliflozin 10 MG|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Beta-cryptoxanthin Bioavailability From Biofortified Maize in Humans
Status: COMPLETED
Conditions: β-cryptoxanthin Bioavailability From Biofortified Maize in Humans
Interventions: OTHER: Whole grain high-BCX maize|OTHER: Refined grain high-BCX maize|OTHER: Whole grain white maize
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Schisandra Chinensis Extract on Musculoskeletal Biomakers in Relatively Sarcopenic Adults: a RCT
Status: COMPLETED
Conditions: Muscular Sarcoidosis
Interventions: DIETARY_SUPPLEMENT: Schisandra chinensis extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Efficacy of Balstilimab in Combination With Botensilimab for the Treatment of Non-Small Cell Lung Cancer (IMMONC0008)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Botensilimab + Balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Breast Surgery Under Tumescent Local Anaesthesia Versus General Anaesthesia ( TLA-001 )
Status: RECRUITING
Conditions: Breast Carcinoma|Breast Carcinoma in Situ
Interventions: PROCEDURE: General Anaesthesia|PROCEDURE: Local tumescent anaesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-injection Adductor Canal Block for Total Knee Arthroplasty Under Spinal Anesthesia
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: PROCEDURE: adductor canal block|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass
Status: COMPLETED
Conditions: Cardio-pulmonary Bypass|Coronary Artery Bypass Graft
Interventions: DRUG: pexelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Added Value of Local Clonidine for Spine Postoperative Pain Control, in Addition to Bupivacaine
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: DRUG: Bupivacaine|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Orientation and Visual Acuity of Four Toric Soft Contact Lenses When Head is Tilted at 90 Degrees
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: senofilcon A|DEVICE: balafilcon A toric|DEVICE: lotrafilcon B toric|DEVICE: omafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compare of Surgical Condition and Complications With Moderate and Deep NM Block
Status: UNKNOWN
Conditions: Neuromuscular Blockade
Interventions: DRUG: Rocuronium|DRUG: cis-atracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACCEL-LOADING-ACS Study
Status: COMPLETED
Conditions: Platelet Aggregation Inhibitors|Anti-inflammatory Agent|Myocardial Reperfusion Injury
Interventions: DRUG: Dual Anti-Platelet Therapy (DAPT)|DRUG: Triple Anti-Platelet Therapy (TAPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Implications of Transcatheter Tricuspid Valve Repair in HFpEF Patients
Status: UNKNOWN
Conditions: Congestive Heart Failure|Tricuspid Regurgitation
Interventions: DEVICE: Transcatheter tricuspid valve edge-to-edge repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Trial Comparing Titan Stent With Zotarolimus-Eluting Stent
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DEVICE: Helistent Titan2 (Titanium coated stent)|DEVICE: EndeavorTM (Zotarolimus-Eluting Stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Second COVID-19 Vaccine Booster in Chinese Adults
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Intramuscularly administered Ad5-nCoV vaccine|BIOLOGICAL: Aerosolized Ad5-nCoV|BIOLOGICAL: DelNS1-2019-nCoV-RBD-OPT1|BIOLOGICAL: SYS6006
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life
Status: NOT_YET_RECRUITING
Conditions: Primary Spontaneous Pneumothorax|Quality of Life|Ambulatory Care|Chest Tube
Interventions: OTHER: Ambulatory management|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Physical Vibration Lithecbole(EPVL) Versus Traditional Row of Stone After Retrograde Intrarenal Surgery(RIRS)
Status: UNKNOWN
Conditions: Renal Calculi
Interventions: PROCEDURE: Retrograde Intrarenal Surgery|PROCEDURE: EPVL after RIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Pharmacokinetic Characteristics and the Safety Between Zeropix and Champix in Healthy Adult Male Subjects.
Status: COMPLETED
Conditions: Smoking, Cigarette
Interventions: DRUG: Zeropix|DRUG: Champix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary
Interventions: DRUG: liraglutide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment for a New UV-protected Pump Infusion Line in Intravenous Infusion Therapy
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: DEVICE: Nimodipine pump infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial
Status: COMPLETED
Conditions: Diarrhea|Antibiotic Associated Diarrhea
Interventions: DRUG: Lactobacillus reuteri DSM 17938|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and Survival
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|Mismatch Repair Deficiency|Microsatellite Instability High
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vivacit-E Post-market Follow-up Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Avascular Necrosis of Bone of Hip|Post-traumatic; Arthrosis|Congenital Hip Dysplasia
Interventions: DEVICE: Vivacit-E Liner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin for Immunomudulation in Sepsis
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: amido pill|DRUG: atorvastatina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-center Clinical Study of Guli Capsules in the Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Guli capsule|DRUG: Kangguzengsheng capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TTI-101|DRUG: Pembrolizumab|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT7, MAGE-A3, and WT1 mRNA-electroporated Autologous Langerhans-type Dendritic Cells as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: CT7, MAGE-A3, and WT1 mRNA-electroporated Langerhans cells ( LCs)|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobacco and Socioeconomic Disadvantage
Status: COMPLETED
Conditions: Tobacco Smoking
Interventions: BEHAVIORAL: Motivational Interviewing|DRUG: Nicotine Replacement Therapy Sampling|BEHAVIORAL: Referral Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholinergic Augmentation in Frequently Falling Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Donepezil|DRUG: Sugar Pill (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Danhong Injection in the Treatment of Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Stroke
Interventions: DRUG: Danhong injection|PROCEDURE: Standard medical care|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Orally Administered SP-303 for the Treatment of Diarrhea in Acquired Immunodeficiency Syndrome (AIDS) Patients
Status: COMPLETED
Conditions: Diarrhea|HIV Infections
Interventions: DRUG: Crofelemer
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Translation of a Novel Brain PET Insert for Simultaneous PET/MR
Status: UNKNOWN
Conditions: Brain Disease
Interventions: DIAGNOSTIC_TEST: Injected radiotracer with PET Insert|DIAGNOSTIC_TEST: Pre-injected group with PET insert
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Regenerative Endodontic Procedure of Immature Permanent Teeth With L-PRF: a Pilot Controlled, Clinical Trial
Status: COMPLETED
Conditions: Endodontic Inflammation
Interventions: PROCEDURE: REP with L-PRF|PROCEDURE: REP|BIOLOGICAL: stem and progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anodal Transcranial Direct Current Stimulation Over the Contralesional Hemisphere on Motor Recovery in Subacute Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Transcranial Direct Current Stimulation|Recovery of Function|Neurological Rehabilitation
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Near-infrared Light Therapy for Mild-Moderate Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: NirsCure|DEVICE: sham NirsCure|DEVICE: NirsCure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Status: COMPLETED
Conditions: Triple-Negative Breast Cancer
Interventions: DRUG: Atezolizumab|DRUG: Ipatasertib|DRUG: Paclitaxel|DRUG: Placebo for Atezolizumab|DRUG: Placebo for Ipatasertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib in Treating Patients With Advanced Systemic Mastocytosis
Status: TERMINATED
Conditions: Aggressive Systemic Mastocytosis|Mast Cell Leukemia|Systemic Mastocytosis
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interactive Gentle Yoga in Improving Quality of Life in Patients With Stage I-III Breast Cancer Undergoing Radiation Therapy
Status: TERMINATED
Conditions: Anxiety Disorder|Depression|Ductal Breast Carcinoma in Situ|Fatigue|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: PROCEDURE: yoga therapy|OTHER: internet-based intervention|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Intra-Patient Escalation Dosing Regimen With IMCgp100 in Patients With Advanced Uveal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma
Interventions: DRUG: IMCgp100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Artificial Sweeteners (AFS) on Sweetness Sensitivity and Preference - Pilot
Status: COMPLETED
Conditions: Impairment of Oral Perception
Interventions: DIETARY_SUPPLEMENT: Sucralose|DIETARY_SUPPLEMENT: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interest of Measuring Lung Elasticity ELASTOgraphy in the Fetus in the Case of PreMAture Childbirth Threat
Status: COMPLETED
Conditions: Pregnancy Complications|Obstetric Labor, Premature
Interventions: OTHER: lung and liver elastography measurement of fetus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Imaging of Subchondral Bone in Knee Osteoarthritis : Predictive Model
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Joint Disease|Arthritis|Musculoskeletal Disease
Interventions: DIAGNOSTIC_TEST: multimodal imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1, Open-Label Study to Evaluate the Effect of a Low-Fat Meal and Multiple Doses of Ciprofloxacin on the Pharmacokinetics of Vorasidenib in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Vorasidenib 40 mg Oral Tablet|DRUG: Ciprofloxacin 500 mg Oral Tablet|DRUG: Vorasidenib 10 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of NMB (Company's Name) Drug Ejecting Balloon for Arteriovenous Fistulae
Status: UNKNOWN
Conditions: Obstructive Lesions of Arteriovenous Dialysis Fistulae
Interventions: DEVICE: PTA Balloon catheter with paclitaxel|PROCEDURE: Plain Balloon angioplasty (PBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Automatic Oxygen Control (CLAC-4) in Preterm Infants
Status: COMPLETED
Conditions: Infant Respiratory Distress Syndrome|Ventilator Lung; Newborn
Interventions: DEVICE: Closed-loop automatic oxygen control (CLAC) fast in addition to RMC|DEVICE: Closed-loop automatic oxygen control (CLAC) slow in addition to RMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bright Light on Fatigue in Women Being Treated for Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer|Cancer of Breast|Cancer of the Breast
Interventions: OTHER: Bright blue-green light using light visor cap|OTHER: Dim red light using light visor cap|OTHER: European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire|OTHER: Epworth Sleepiness Scale|OTHER: Pittsburgh Sleep Quality Index|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance|OTHER: Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue|DIAGNOSTIC_TEST: Digital foot candle datalogging light meter (Extech Instrument, Model SDL400)|DIAGNOSTIC_TEST: Polysomnography (Easy Ambulatory 2 Cadwell, Kennewick, WA)|OTHER: Horne-Ostberg Morningness-Eveningness Questionnaire|OTHER: Daily Fatigue and Sleep Log
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epirubicin for the Treatment of Sepsis & Septic Shock
Status: RECRUITING
Conditions: Sepsis
Interventions: DRUG: Epirubicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID 19 : Seroprevalence Study of Anti SRAS-CoV-2 Antibodies in GHT Employees in Haute Bretagne (AntiCoV-HB)
Status: COMPLETED
Conditions: Coronavirus
Interventions: DIAGNOSTIC_TEST: NG test|DIAGNOSTIC_TEST: Blood test|BEHAVIORAL: Self-questionnary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of Combining Irinotecan With 5-FU, Leucovorin/Folinic Acid, Oxaliplatin, and Docetaxel Chemotherapies
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Adenocarcinoma
Interventions: DRUG: Oxaliplatin|DRUG: Docetaxel|DRUG: Leucovorin|DRUG: Irinotecan|DRUG: 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Radiotherapy to Standard Medical Treatment for Stage IV NSCLC
Status: RECRUITING
Conditions: Radiotherapy|Non Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Quality of Life
Interventions: RADIATION: Thoracic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chuna Manual Treatment for Patients With Primary Dysmenorrhea Primary Dysmenorrhea
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: PROCEDURE: Chuna therapy|PROCEDURE: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome (MDS)|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: IRX5183
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Human Mesenchymal Stem Cell Infusion vs Placebo in Alcohol Use Disorder and Major Depression.
Status: RECRUITING
Conditions: Major Depressive Disorder|Alcohol Use Disorder
Interventions: DRUG: allogeneic human mesenchymal stem cells (allo-hMSCs)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lean Body Mass Response to Higher-protein Diets During Winter Military Training
Status: COMPLETED
Conditions: Body Weight
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Protein|DIETARY_SUPPLEMENT: Carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving Embryogenesis by Adding Growth Factors to In Vitro Human Culture Media
Status: COMPLETED
Conditions: In Vitro Human Embryo Development
Interventions: OTHER: Growth Factors and Cytokine adding to embryo culture media|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Total Intravenous Anesthesia and Recurrence Free Survival
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Propofol-based total intravenous anesthesia|DRUG: Sevoflurane intravenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Hypofractionated Intensity - Modulated Radiotherapy After Hyperbaric Oxygenation for Recurrent High Grade Glioma.
Status: RECRUITING
Conditions: Malignant Glioma|High Grade Glioma|Recurrent Glioma
Interventions: DEVICE: HBO|RADIATION: RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Oral Penicillin Challenge in Low Risk Hospitalized Patients
Status: NOT_YET_RECRUITING
Conditions: Penicillin Allergy
Interventions: DRUG: Amoxicillin 250 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Characterize Event Related Potential Markers of Attentional Bias Towards Words and Images of Food
Status: TERMINATED
Conditions: Obesity
Interventions: OTHER: High calorie lunch|OTHER: Breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bryostatin 1 in Treating Patients With Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: bryostatin 1|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Avatrombopag for the Treatment of Thrombocytopenia in Japanese Adults With Chronic ITP
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Avatrombopag Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Iron Deficiency Anemia on HBA1C in Patients With Diabetic Foot Ulcer Grade (1and2)
Status: UNKNOWN
Conditions: Iron Deficiency Anemia|HBA1C
Interventions: DIAGNOSTIC_TEST: CBC ,Serum ferritin ,HBA1C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of and Immune Response to a Dengue Virus Vaccine (rDEN1delta30) in Healthy Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: rDEN1delta30|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Oral Probiotics on the Microbiome and Lipidome
Status: COMPLETED
Conditions: Gut Microbiome|Skin Microbiome|Gut Lipidome|Skin Lipidome|Blood Lipidome
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: SYMPROVE III: Health Services Research Study for Treatment of the Moderate and Severe Acute Exacerbations of Chronic Bronchitis (AECB)
Status: COMPLETED
Conditions: Chronic Bronchitis
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Utilization of 31P-Nuclear Magnetic Resonance Spectroscopy to Monitor Brain Energy Deficit in Huntington Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: OTHER: 31-Phosphorus RMN Spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy
Status: COMPLETED
Conditions: Stage III Esophageal Squamous Cell Carcinoma|Stage II Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Megestrol（Yining）|RADIATION: radiotherapy|OTHER: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rare Diseases Clinical Research Network: Neurophysiological Correlates
Status: COMPLETED
Conditions: Rett Syndrome, Preserved Speech Variant|Mecp2 Duplication Syndrome|Rett-related Disorders
Interventions: PROCEDURE: Auditory and Visual Event-related Potentials and EEG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Immunomodulatory Therapy in High Risk Solitary Bone Plasmacytoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasmacytoma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|OTHER: No further treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROCEDYTE: Depocyte® Administration (Liposomal Cytarabine) as Prophylaxis of Neuromeningeal Infiltration in Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: DepoCyte
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Sucrose to Reduce Pain in Sick Babies
Status: TERMINATED
Conditions: Pain Due to Certain Specified Procedures
Interventions: DRUG: 24% sucrose po solution|DRUG: Placebo po
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery
Status: COMPLETED
Conditions: Impaired Cognition|Quality of Life|Surgery|Delirium|Colorectal Carcinoma|Bladder Carcinoma|Abdominal Hysterectomy (& Wertheim)|Prostatic Neoplasms|Colon Carcinoma|Renal Carcinoma
Interventions: OTHER: Exercise Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sutures Versus Polyglactin Mesh in Hiatal Hernia Repair
Status: RECRUITING
Conditions: Paraesophageal Hernia|Hiatal Hernia|Hiatal Hernia, Paraesophageal|Recurrence
Interventions: PROCEDURE: Polyglactin mesh|PROCEDURE: Sutures only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis
Status: COMPLETED
Conditions: Myocardial Infarction|Influenza, Human|Influenza Vaccines|Heart Failure|Stroke
Interventions: BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity of Incentive Spirometry on Postoperative Pulmonary Complication After Major Abdominal Surgery
Status: COMPLETED
Conditions: Incentive Spirometry|Postoperative Pulmonary Complication|Major Abdominal Surgery
Interventions: DEVICE: respiratory exercise with incentive spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: New Biomarkers Associated With the Risk of Premature Delivery.
Status: COMPLETED
Conditions: Premature Delivery
Interventions: OTHER: 2 tubes of 5ml during the blood collection and 2 swabs during vaginal sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Exploratory Efficacy Study of NEUROSTEM® Versus Placebo in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: human umbilical cord blood derived mesenchymal stem cells|OTHER: Normal saline 2mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on Metabolomics
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Coronary Heart Disease|Lipid Metabolism Disorders
Interventions: DIAGNOSTIC_TEST: lipid metabolomics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p