pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness & Cost-effectiveness of Internet-delivered Interventions for Depression and Anxiety Disorders in IAPT
Status: UNKNOWN
Conditions: Depression|Anxiety Disorders|Depressive Disorder|Generalized Anxiety Disorder|Social Anxiety Disorder|Phobic Disorders|Panic Disorder|Health Anxiety
Interventions: BEHAVIORAL: SilverCloud Internet-delivered Cognitive Behavioural Therapy|OTHER: Waiting List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Relaxin for the Treatment of Decompensated CHF
Status: TERMINATED
Conditions: Congestive Heart Failure (CHF)
Interventions: DRUG: Placebo|DRUG: Recombinant human relaxin (rhRlx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Lactobacillus Reuteri in Healthy Children Aged 2-24 Months
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Lactobacillus reuteri 17938|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Biomarkers in Ischemic Stroke - Clinical Trial
Status: COMPLETED
Conditions: Stroke, Ischemic|Stroke Hemorrhagic
Interventions: GENETIC: blood samples|DIAGNOSTIC_TEST: MRI without injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prostate Core Needle Biopsy
Status: COMPLETED
Conditions: Biopsy|Prostate|Complication
Interventions: DEVICE: coaxial prostate biopsy|DEVICE: noncoaxial prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections
Status: TERMINATED
Conditions: Catheter-Related Infections
Interventions: OTHER: Ethanol lock|OTHER: Heparin lock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Acral Malignant Melanoma
Status: UNKNOWN
Conditions: Advanced Acral Malignant Melanoma
Interventions: DRUG: Anlotinib|DRUG: TQB2450
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19-redirected Autologous Cells (CAR-CD19 T Cells)
Status: UNKNOWN
Conditions: CD19 Positive Malignant B-cell Leukemia and Lymphoma
Interventions: GENETIC: CAR-CD19 T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forced Oscillation Versus Spirometry in Diagnosing Post Pulmonary Transplant Bronchiolitis Obliterans Syndrome
Status: COMPLETED
Conditions: Bronchiolitis Obliterans Syndrome
Interventions: OTHER: Forced oscillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Docetaxel and Capecitabine With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Docetaxel|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Pathophysiology of Long Term Implications
Status: UNKNOWN
Conditions: Covid19|Pulmonary Fibrosis|Organising Pneumonia|Thromboembolism
Interventions: OTHER: Cryo lung biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Program for the Comprehensive Neurocognitive Treatment of Excess Weight
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Approach-Avoidance Bias Modification|BEHAVIORAL: Inhibition Training|BEHAVIORAL: Implementation of Intentions|BEHAVIORAL: Episodic Future Thinking|BEHAVIORAL: Sham Approach-Avoidance Bias Modification|BEHAVIORAL: Sham Inhibition Treatment|BEHAVIORAL: Setting Intentions|BEHAVIORAL: Recent Episodic Thinking|BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Nutritional intervention|BEHAVIORAL: Physical exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF)
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DEVICE: Radiofrequency electromagnetic field treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children
Status: UNKNOWN
Conditions: Enteral Nutrition|Feeding Intolerance|Intestinal Fatty Acid Binding Protein
Interventions: OTHER: Feeding intolerance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bridging the Childhood Epilepsy Treatment Gap in Africa
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: OTHER: Task-shifting of follow-up care for pediatric epilepsy|OTHER: Enhanced usual care for pediatric epilepsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Muscadine Plus (MPX) In Men With Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate
Interventions: DRUG: Muscadine Plus|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine Safety and Tolerability of MG-S-2525 and to Evaluate Its PK Profile in Healthy Volunteers
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: MG-S-2525
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD Treatment and Emotion Regulation Skills Training for Veterans With Military Sexual Trauma (PE+ER)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Anxiety Disorders|Mental Disorder|Traumatic Stress Disorder
Interventions: BEHAVIORAL: PE+ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Efficacy of Neuroprotective Drugs Administered Topically to Prevent or Arrest Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: COLIRIOBCN070660|DRUG: Placebo|DRUG: Brimonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of UC With Novel Therapeutics
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis Mild|Ulcerative Colitis
Interventions: DRUG: BRS201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of a Multimodal Prehabilitation Pancreatic Cancer Program
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: BEHAVIORAL: Exercise Program|BEHAVIORAL: Nutrition Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The ENDEAVOR Pharmacokinetic (PK) Registry: The Medtronic Endeavor Drug Eluting Coronary Stent System
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Coronary Artery Stenting|DEVICE: Endeavor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance ZD1839 (IRESSA®) Following Completion of Front Line, Platinum-Based, Double Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Non-cystic Fibrosis Bronchiectasis to Test How Well Different Doses of BI 1323495 Are Tolerated and How BI 1323495 Affects Biomarkers of Inflammation
Status: COMPLETED
Conditions: Non-cystic Fibrosis Bronchiectasis
Interventions: DRUG: BI 1323495|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia
Status: COMPLETED
Conditions: Hyperammonemia
Interventions: DRUG: TNP-2092 capsules|DRUG: TNP-2092 capsules Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Depression Self-stigma and Increasing Treatment Seeking Intentions Among Youth
Status: COMPLETED
Conditions: Stigma, Social|Mental Health Disorder|Depression
Interventions: BEHAVIORAL: Brief video intervention (Black Woman)|BEHAVIORAL: Brief video intervention (Latinx Woman)|BEHAVIORAL: Brief video intervention (White Woman)|BEHAVIORAL: Vignette Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Smartphone Application, GoCheckKids™ as a Photo Screening Tool in a Pediatric Population
Status: COMPLETED
Conditions: Amblyopia
Interventions: DEVICE: GoCheck Kids (iOS)|DEVICE: GoCheck Kids (Windows)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Training, Detraining, Retraining and Glycemic Control in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Training - detraining - retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Status: RECRUITING
Conditions: Non-Alcoholic Steatohepatitis|Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Vaccine for Reducing Ear and Lung Infections in Children
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK2189242A|BIOLOGICAL: Placebo|BIOLOGICAL: Prevnar 13®|BIOLOGICAL: PedvaxHIB®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Gender on Depression and Periodontal Status
Status: COMPLETED
Conditions: Periodontal Diseases|Depression|Gender|Gingival Diseases
Interventions: OTHER: Psychological measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of BuMA eG Based BioDegradable Polymer Stent With EXCEL Biodegradable Polymer Sirolimus-eluting Stent in "Real-World" Practice
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: BuMA|DEVICE: EXCEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Comparing Ventilation Modes During CPR With Mechanical Compression Device.
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation
Interventions: PROCEDURE: Volume controlled ventilation|PROCEDURE: Pressure controlled ventilation|PROCEDURE: CPAP mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dl-3-n-butylphthalide and Cerebrolysin Treatment in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Cerebral Stroke Within 12 Hours for the First Time
Interventions: DRUG: Dl-3-n-butylphthalide|DRUG: Cerebrolysin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Iguratimod Effect on Lupus Nephritis (IGeLU)
Status: UNKNOWN
Conditions: Lupus Nephritis
Interventions: DRUG: Iguratimod|DRUG: Cyclophosphamide|DRUG: Azathioprine|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saphenous Vein Cannulation in Infants and Small Children
Status: COMPLETED
Conditions: Saphenous Vein Cannulation
Interventions: PROCEDURE: Saphenous vein cannulation|DEVICE: ultrasound with a linear transducer (L15-7io)|DEVICE: A 22 or 24 G intravenous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Cardiovascular Risk Following Conversion to Full Dose Myfortic® and Neoral® Two-hour Post Level Monitoring
Status: WITHDRAWN
Conditions: Cardiovascular Disease|Cardiovascular Outcomes|Kidney Transplant Recipients|Kidney Transplantation
Interventions: DRUG: Myfortic®|DRUG: Neoral®|DRUG: Cellcept®|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoantigen Reactive T Cells c for Chinese Patients With Advanced Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Gastric Cancer
Interventions: BIOLOGICAL: Neoantigen Reactive T Cells(NRTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan
Status: COMPLETED
Conditions: Acute Lung Injury|Systemic Inflammatory Response Syndrome
Interventions: DRUG: Sivelestat sodium hydrate|DRUG: Sivelestat sodium hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Potential Screening Tools for Detecting Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: PROCEDURE: [123I]β-CIT and SPECT imaging|DRUG: [123I]β-CIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms
Status: UNKNOWN
Conditions: Depressive Disorder, Major
Interventions: DRUG: Psilocybin + Placebo|DRUG: Psilocybin + Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Impact of Subcutaneous Irrigation on Wound Complications
Status: COMPLETED
Conditions: Cesarean Section; Complications, Wound, Hematoma
Interventions: OTHER: subcutaneous saline irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Intravenous Magnesium Sulfate on Intraocular Pressure Following Tracheal Intubation
Status: COMPLETED
Conditions: Increased Intra Ocular Pressure (IOP)
Interventions: DRUG: Magnesium Sulfate|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of Catheter Contact by Evaluation of Microelectrode Near-Field Signals
Status: COMPLETED
Conditions: Cardiac Catheter Ablation|Atrial Flutter|Cardiac Arrhythmias
Interventions: OTHER: Data Collection During Atrial Flutter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment and Treatment of Patients With Long-term Dizziness in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Dizziness|Vertigo|Vestibular Neuritis
Interventions: BEHAVIORAL: BI + VR + CBT|BEHAVIORAL: BI + phone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Ferumoxytol for the Treatment of Iron Deficiency Anemia in Pediatric Participants With Chronic Kidney Disease
Status: TERMINATED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol|DRUG: Oral Iron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Sodium Tanshinone IIA Sulfonate on Pulmonary Hypertension
Status: UNKNOWN
Conditions: Pulmonary Hypertension|Pulmonary Arterial Hypertension|Cardiovascular Diseases|Lung Diseases|Tanshinone IIA Sulfonate
Interventions: DRUG: 20 mg sildenafil citrate by mouth|DRUG: sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Clinical Study of Lutetium Lu 177 JH020002 Injection in Patients With Advanced Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Lutetium Lu 177 JH020002 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Plus Systematic Neoadjuvant Therapy for Recurrent Hepatocellular Carcinoma (RANT Study)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma Recurrent
Interventions: DRUG: Tislelizumab/Sintilimab+Lenvatinib/Bevacizumab|PROCEDURE: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beetroot Extract Supplementation in Chronic Hypertensive Pregnancies
Status: RECRUITING
Conditions: Hypertension in Pregnancy|Hypertension|Pregnancy
Interventions: DIETARY_SUPPLEMENT: Nitrate-enriched Beetroot Extract Capsule|DIETARY_SUPPLEMENT: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Postoperative Hemorrhage
Interventions: DRUG: Acide Tranexamique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin Application Following Removal of Impacted Third Molar
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: 3 mg melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Satiating Properties of a Hybrid Protein Snack Mainly From Chickpeas
Status: UNKNOWN
Conditions: Healthy Nutrition
Interventions: OTHER: Hybrid Snack|OTHER: Meat snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Pseudomonas Aeruginosa|Pneumonia|Hematologic Malignancy
Interventions: DRUG: Ceftolozane / Tazobactam Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Rehydration Solution in Healthy Adults
Status: RECRUITING
Conditions: Dehydration
Interventions: OTHER: Oral Rehydration Solution (ORS)|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Propofol and Sevoflurane Anesthesia on the Quality of Recovery After Ambulatory Surgery in Obese Patients
Status: WITHDRAWN
Conditions: Quality of Recovery
Interventions: DRUG: Propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Serratus Anterior Plane Block and Erector Spinae Plane Block in Coarctectomy
Status: RECRUITING
Conditions: Aortic Coarctation
Interventions: PROCEDURE: block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Imipramine in Treatment of Refractory Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorder
Interventions: DRUG: Imipramine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Late Permissive Hypercapnia for Intubated and Ventilated Preterm Infants
Status: COMPLETED
Conditions: Premature Neonate
Interventions: OTHER: Higher permissive hypercapnia|OTHER: Lower Permissive Hypercapnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Not Anemic and Who Will be Undergoing Orthopedic or Heart and Blood Vessel Surgery
Status: COMPLETED
Conditions: Blood Transfusion|Blood Transfusion, Autologous|Orthopedic Procedures|Orthopedic Surgery|Cardiovascular Surgical Procedure
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Role of Toll-like Receptor-4 Expression in Patients With Interstitial Cystitis/Bladder Pain Syndrome
Status: UNKNOWN
Conditions: Cystitis, Interstitial|Painful Bladder Syndrome
Interventions: PROCEDURE: cystoscopy, bladder hydrodistention and bladder biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Cyberknife Spinal Stereotactic Radiotherapy in Difficult to Treat Cases (IMPRESS)
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: OTHER: Setup and Imaging for at CT radiation planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loss of Cervical Lordosis in Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia, Cervical Lordosis
Interventions: OTHER: Visual Analog Scale (VAS), QOL (36-Item Short Form Survey (SF-36)), and Neck Disability Index (NDI) were used to assess pain, overall quality of life, functional disability respectively.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides in Postmenopausal Women With Osteopenia
Status: COMPLETED
Conditions: Osteopenia|Postmenopausal Osteopenia
Interventions: DIETARY_SUPPLEMENT: Calcium, vitamin D and bioactive collagen peptides supplement|DIETARY_SUPPLEMENT: Calcium and vitamin D supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cefadroxil 500 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefadroxil 500 mg Capsules|DRUG: DURICEF® capsules 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of Vitamin C to Augment Iron Chelation With DFP or DFX
Status: UNKNOWN
Conditions: Vitamin c|Thalassemia Major|Iron Chelation
Interventions: DRUG: Vitamin C, Defriprone, deferisarox|DRUG: deferiprone , deferesarox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2018_28
Status: COMPLETED
Conditions: Hearing Loss|Sensorineural Hearing Loss
Interventions: DEVICE: Successor of Phonak Audéo B90|DEVICE: Phonak Audéo B90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Cost Analysis of Plastic Stent Compare to Metallic Stent in Hilar Cholangiocarcinoma
Status: COMPLETED
Conditions: Hilar Cholangiocarcinoma
Interventions: DEVICE: biliary stent (self expandable metallic stent)|DEVICE: PS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Specific Biomechanical Modeling of Abdominal Aortic Aneurysm to Improve Aortic Endovascular Repair
Status: RECRUITING
Conditions: Aortic Aneurysm
Interventions: OTHER: Biomechanical computer program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LiquiBand® Exceed™ and LiquiBand® Rapid™ for General Surgery Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Wound
Interventions: DEVICE: LiquiBand Exceed|DEVICE: LiquiBand Rapid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TJ107 in Chinese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumord
Interventions: DRUG: TJ107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoid vs Opioid for Photorefractive Keratectomy Pain Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Photorefractive Keratectomy|Myopia|Hyperopia
Interventions: DRUG: oral cannabinoid|COMBINATION_PRODUCT: oral codeine/acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Immunosuppressive Therapy on the Course of Vogt-Koyanagi-Harada Disease
Status: RECRUITING
Conditions: Vogt Koyanagi Harada Disease
Interventions: DRUG: Early high-dose corticosteroid and immunosuppressive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Functional Analysis of Salivary Glands and Correlation With Sialoscintigraphy in Sjogren's Syndrome
Status: RECRUITING
Conditions: Sjogren's Syndrome
Interventions: RADIATION: Sialoscintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.
Status: TERMINATED
Conditions: Motor Neuron Disease
Interventions: DRUG: FLX-787-ODT (orally disintegrating tablet)|DRUG: Placebo ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ease of Use of New Blood Glucose Meter With In-built Insulin Calculator at Home Study
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: ADC blood glucose meter|DEVICE: Comparator blood glucose meter|DEVICE: ADC blood glucose meter with insulin calculator active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Management of Low Back Pain in the Emergency Department With Different Analgesic Dosages"
Status: COMPLETED
Conditions: Low Back Pain, Mechanical|Ibuprofen|Analgesia|Pain Management
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Ibuprofen 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Pharynx in Patients Undergoing Lateral Pharyngoplasty
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: PROCEDURE: LATERAL PHARYNGOPLASTY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrated Behavioral Healthcare for Youth With Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Behavioral Care Coordinated with Medical Care Intervention|BEHAVIORAL: Behavioral Care Not Coordinated with Medical Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ED50 and ED95 of Intrathecal Bupivacaine With or Without Epinephrine for Total Knee Replacement Arthroplasty
Status: COMPLETED
Conditions: Spinal Anesthesia|Total Knee Replacement Arthroplasty
Interventions: DRUG: intrathecal bupivacaine 6 mg with 100 mcg of epinephrine|DRUG: intrathecal bupivacaine 7 mg with 100 mcg of epinephrine|DRUG: intrathecal bupivacaine 8 mg with 100 mcg of epinephrine|DRUG: intrathecal bupivacaine 9 mg with 100 mcg of epinephrine|DRUG: intrathecal bupivacaine 10 mg with 100 mcg of epinephrine|DRUG: intrathecal bupivacaine 11 mg with epinephrine 100 mcg|DRUG: intrathecal bupivacaine 6 mg with 200 mcg of epinephrine|DRUG: intrathecal bupivacaine 7 mg with 200 mcg of epinephrine|DRUG: intrathecal bupivacaine 8 mg with 200 mcg of epinephrine|DRUG: intrathecal bupivacaine 9 mg with 200 mcg of epinephrine|DRUG: intrathecal bupivacaine 10 mg with 200 mcg of epinephrine|DRUG: intrathecal bupivacaine 11 mg with 200 mcg of epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: An Observational Study to Assess Next Generation Emulsion Preservative Free Eye Drops (NGE-UD) on Dry Eye Symptoms and Quality of Life of Adult Participants With Mild to Moderate Dry Eye Disease (DED)
Status: RECRUITING
Conditions: Dry Eye
Interventions: DRUG: Next Generation Emulsion Preservative Free Eye Drops (NGE-UD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of HSK21542 in a Peritoneal Dialysis Pruritus Population.
Status: NOT_YET_RECRUITING
Conditions: Pruritus
Interventions: DRUG: HSK21542 tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMPOWER: Effects of Weight Loss and Exercise Post-stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Stroke
Interventions: OTHER: Lifestyle Management Program|OTHER: Post-stroke Optimization of Walking using Explosive Resistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intracochlear Application of VSF1.01 for the Reduction of Cochlear Implant Surgery Related Trauma
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss
Interventions: DRUG: Intracochlear application of VSF1.01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of a Novel Implantable Neurostimulator for Ameliorate Erectile Function on Spinal Cord Injured Patients
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Erectile Dysfunction
Interventions: DEVICE: Implantation of the caverStim device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPERA: French Observational Study on Patients Implanted With a Guidant PRIZM or Vitality Defibrillator
Status: COMPLETED
Conditions: Ventricular Tachycardia|Ventricular Fibrillation
Interventions: DEVICE: Prizm, Vitality, Renewal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robot-Assisted Training Versus Standard Training in Ischemic Stroke
Status: RECRUITING
Conditions: Stroke|Ischemic Stroke
Interventions: OTHER: Robot-assisted Training|OTHER: Standard Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suitability of PICC for Transpulmonary Thermodilution Compared to CICC
Status: COMPLETED
Conditions: Peripherally Inserted Central Catheters|CVC|Transpulmonary Thermodilution|Hemodynamic Monitoring
Interventions: DIAGNOSTIC_TEST: transpulmonary thermodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis (AGES-Mind)
Status: COMPLETED
Conditions: Schizophrenia and Disorders With Psychotic Features|Psychotic Episode
Interventions: BEHAVIORAL: SocialMIND|BEHAVIORAL: Psychoeducational multicomponent intervention|BEHAVIORAL: Psychosocial treatment|DRUG: Psychotropic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapeutic Interventions Applied to the Bladder Pain Syndrome
Status: COMPLETED
Conditions: Interstitial Cystitis|Painful Bladder Syndrome|Bladder Pain Syndrome
Interventions: DEVICE: TENS|BEHAVIORAL: Postural exercises|DEVICE: Biofeedback|BEHAVIORAL: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Nurse-led Smartphone-based Self-management Programme for Type 2 Diabetes Patients With Poor Blood Glucose Control
Status: UNKNOWN
Conditions: Type2 Diabetes Mellitus
Interventions: BEHAVIORAL: nurse-led smartphone-based self-management programme|BEHAVIORAL: exiting nurse-led diabetes service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy
Status: NOT_YET_RECRUITING
Conditions: Biliary Atresia
Interventions: DRUG: OCA|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Non-Alcoholic Steatohepatitis (NASH) in Adult Participants at Increased Genetic Risk for This Condition
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis (NASH)|Metabolic Dysfunction Associated Steatohepatitis (MASH)
Interventions: DRUG: ALN-HSD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bile Acid Malabsorption With Liraglutide
Status: COMPLETED
Conditions: Bile Acid Malabsorption
Interventions: DRUG: Liraglutide 6 MG/ML|DRUG: Colesevelam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radical Prostatectomy Versus Radical Radiotherapy for Locally Advanced Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: Radical Prostatectomy|OTHER: Radical Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT
Status: RECRUITING
Conditions: Oral Mucositis|Hematopoietic Neoplasm|Xerostomia|Hyposalivation
Interventions: DEVICE: Photobiomodulation therapy (intraoral)|DEVICE: Photobiomodulation therapy (extraoral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study
Status: RECRUITING
Conditions: Sacubitril/Valsartan|Hypertension|Obesity
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]|DRUG: ACEI/ARB
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ChimeriVax™-JE Live Attenuated Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Encephalitis|Japanese Encephalitis
Interventions: BIOLOGICAL: Live attenuated Japanese encephalitis virus, then ChimeriVax diluent|BIOLOGICAL: ChimeriVax diluent, then Live attenuated Japanese encephalitis virus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
Status: COMPLETED
Conditions: Brain Tumors|Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: lomustine|DRUG: mesna|DRUG: vincristine sulfate|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers Correlation With Volemia
Status: COMPLETED
Conditions: Cerebral Hemorrhage|Head Injury|Non Traumatic Post Surgery|Poly Trauma Patients Without Heart Failure|Renal Insufficiency
Interventions: OTHER: Biomarkers, red blood cells and plasma assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of A-319 in Patients With Relapsed or Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed or Refractory B-cell Lymphoma
Interventions: BIOLOGICAL: Recombinant Anti-CD19m-CD3 Antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aspirin Resistance and Stroke Risk: Platelet Function Analysis in Patients With Ischemic Events
Status: COMPLETED
Conditions: Stroke|Myocardial Infarctions
Interventions: DRUG: Clopidogrel|DRUG: Aspirin 81 mg|DRUG: Aspirin >300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 48 Weeks, Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO)
Status: COMPLETED
Conditions: Hypothalamic Injury-induced Obesity (HIO)
Interventions: DRUG: Tesofensine/Metoprolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zevalin-BEAM/BEAC With Autologous Stem Cell Support as Consolidation in First Line Treatment of Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: 90Y-ibritumomab tiuxetan (Zevalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-Fluciclovine PET and Multiparametric MR Imaging
Status: WITHDRAWN
Conditions: Brain Tumor, Recurrent, Adult
Interventions: DRUG: PET/CT with F-Fluciclovine (Axumin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Impact of Apremilast (CC-10004) on Quality of Life, Efficacy, and Safety in Adults With Manifestations of Plaque Psoriasis and Impaired Quality of Life
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Rituximab in Adults With Chronic and Severe Immune Thrombocytopenic Purpura and Candidate for a Splenectomy
Status: TERMINATED
Conditions: Autoimmune Thrombocytopenic Purpura
Interventions: DRUG: Mabthéra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-centered Outcomes After Permanent Female Sterilization Procedure(POPS Trial)
Status: RECRUITING
Conditions: Sterility, Female
Interventions: DEVICE: Traditional laparoscopy|DEVICE: Single site laparoscopy|DEVICE: V-Notes surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characteristics and Outcomes of Acute Myeloid Leukemia (AML) Patients Treated With Oral-Azacitidine Maintenance Therapy in France
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Oral azacitidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy
Status: COMPLETED
Conditions: Distal Pancreatectomy|Spleen Preservation|Postpancreatectomy Hemorrhage
Interventions: PROCEDURE: Splenic vessels preservation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Electrophysiological Signature of the Mental Fatigue-induced Impairment in Endurance Performance
Status: UNKNOWN
Conditions: Mental Fatigue|Electroencephalography
Interventions: OTHER: Mental Fatigue (Stroop task)|OTHER: Control (Documentary)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacology of Insulin Injected With Jet-Injection
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: jet injector (SQ pen/Novopen III)|DEVICE: jet injector (SQ pen/Novopen III)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Could Ki-67 be Used as a Diagnostic or Prognostic Marker in Hemato-oncological Diagnostics?
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes|Acute Myeloid Leukemia|Myelodysplastic Syndrome/Neoplasm
Interventions: DIAGNOSTIC_TEST: Flow cytometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigating How Incentives Impact Engagement With an Online Mental Health Application (Neuroflow)
Status: COMPLETED
Conditions: Behavioral Economics|Gifts, Financial|Point
Interventions: BEHAVIORAL: Neuroflow app: Mental health and wellbeing resources for adults
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mammography and Breast Arterial Calcification: An Information-Sharing Trial
Status: RECRUITING
Conditions: Mammography|Vascular Calcification
Interventions: BEHAVIORAL: BAC-Enhanced Letter|BEHAVIORAL: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE)
Status: COMPLETED
Conditions: Pseudoxanthoma Elasticum
Interventions: DRUG: Magnesium Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Level Lazer Therapy Effect on Vertebral Artery Blood Flow in Elderly With Cervical Disc Degeneration
Status: NOT_YET_RECRUITING
Conditions: Disc Degeneration
Interventions: RADIATION: Low level Lazer therapy|OTHER: Routine exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT