pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Conventional vs Neurally Adjusted Ventilatory Assist in Difficult Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Neurally adjusted ventilatory assist|DEVICE: Noninvasive pressure support ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Interactions Between Buprenorphine and Kaletra (Lopinavir/Ritonavir)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Kaletra (lopinavir/ritonavir)|DRUG: buprenorphine|OTHER: Clinical evaluations/Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating Systemic Exposure and Pharmacodynamics in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: fluticasone propionate/formoterol fumarate|DRUG: fluticasone propionate|DRUG: formoterol fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Breathing,Self-Help Book in Cigarette Consumption,Anxiety,Depression and Motivation to Stop Smoking
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Deep Breathing Exercises|BEHAVIORAL: Self-Help Book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GIOTRIF rPMS in Korean Patients With NSCLC
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: GIOTRIF 20mg|DRUG: GIOTRIF 40mg|DRUG: GIOTRIF 30mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors
Status: NOT_YET_RECRUITING
Conditions: Critical Illness|Delirium|Cognitive Impairment|Cognitive Decline|Alzheimer's Disease|Dementia|Circadian Dysrhythmia|Sleep Disturbance
Interventions: BEHAVIORAL: SLEEP + COG|BEHAVIORAL: COG|BEHAVIORAL: SLEEP|BEHAVIORAL: AC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Study of Volixibat in Subjects With Elevated Serum Bile Acids Associated With Intrahepatic Cholestasis of Pregnancy (OHANA)
Status: TERMINATED
Conditions: Intrahepatic Cholestasis of Pregnancy
Interventions: DRUG: Volixibat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lactate Clearance Goal-directed Therapy in Sepsis
Status: UNKNOWN
Conditions: Sepsis
Interventions: BEHAVIORAL: Lactate clearance 10% target group|BEHAVIORAL: Lactate clearance 20% target group|BEHAVIORAL: Standard EGDT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microvascular Coronary Resistance and Absolute Coronary FLOW in Patients With Percutaneous Intervention of a Chronic Total Occlusion
Status: UNKNOWN
Conditions: Chronic Total Occlusion of Coronary Artery|Microvascular Coronary Artery Disease|Coronary; Ischemic|Coronary Microvascular Dysfunction
Interventions: DIAGNOSTIC_TEST: Invasive coronary physiology
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Long Term Effects of Alfuzosin(Xatral XL) in Lower Urinary Tract Symptoms(LUTS)/BPH Patients
Status: COMPLETED
Conditions: BPH
Interventions: DRUG: Alfuzosin|DRUG: Alfuzosin|DRUG: Alfuzosin|DRUG: Alfuzosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of Healthier Wealthier Families in Sweden
Status: RECRUITING
Conditions: Material and Social Deprivation: An Enforced Lack of Necessary and Desirable Items to Lead an Adequate Life
Interventions: BEHAVIORAL: Healthier Wealthier Families
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Supersaturation and Precipitation of Diclofenac in the Stomach of Healthy Volunteers
Status: UNKNOWN
Conditions: Supersaturation and Precipitation in the Stomach
Interventions: DRUG: Diclofenac potassium 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Hericium Erinaceus on Microbiota and Cognition
Status: COMPLETED
Conditions: Cognitive Decline, Mild
Interventions: DIETARY_SUPPLEMENT: Hericium erinaceus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Epacadostat and Pembrolizumab in Patients With Head and Neck Cancer That Have Failed Prior Immunotherapy
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Epacadostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization
Status: UNKNOWN
Conditions: Mastitis
Interventions: BIOLOGICAL: Lactobacillus salivarius PS2|BIOLOGICAL: Excipient (milk powder)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Yangxinshi Tablet Intervention for Exercise Capacity in Patients With Chronic Coronary Syndrome
Status: RECRUITING
Conditions: Chronic Coronary Syndrome
Interventions: DRUG: Yangxinshi tablet|OTHER: Basic medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
Status: COMPLETED
Conditions: Urolithiasis|Urologic Diseases|Urinary Calculi|Urinary Obstruction|Urinary Stone|Ureteric Obstruction|Calculus Ureteral|Stone Ureter|Stone;Renal|Stone, Kidney|Stone, Urinary|Obstruction Ureter|Obstruction|Ureter Calculi|Ureter Obstruction|Kidney Diseases|Kidney Calculi|Kidney Failure, Acute|Kidney Dysfunction|Kidney Insufficiency|Pyelonephritis|Pyelonephritis Acute|Pyelonephritis Obstructive|Pyelonephritis; Calculus|Pyelonephritis; Obstruction|Pyelonephrosis|Hydronephrosis|Hydronephrosis; Infection|Hydronephrosis, Infected|Hydronephrosis; Obstruction, Ureter|Hydronephrosis; Obstruction, Renal Calculus|Hydronephrosis, Secondary|Renal Pelvis; Obstruction
Interventions: DEVICE: Percutaneous Nephrostomy|DEVICE: Double J catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of 131I-TM601 in Adults With Recurrent Malignant Glioma
Status: UNKNOWN
Conditions: Malignant Glioma|Glioblastoma Multiforme|GBM|Astrocytoma|Oligodendroglioma
Interventions: DRUG: 131I-TM601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Status: COMPLETED
Conditions: Autoantibody Positive|Non-diabetic Relatives at Risk for Type 1 Diabetes|High Risk|Impaired Glucose Tolerance
Interventions: DRUG: Teplizumab|DRUG: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Families Moving Forward (FMF) Connect Pro for Mental Health Providers
Status: RECRUITING
Conditions: Fetal Alcohol Spectrum Disorders
Interventions: BEHAVIORAL: FMF (Families Moving Forward) Connect Pro|BEHAVIORAL: ECHO (Extension of Community Healthcare Outcomes) implementation.|BEHAVIORAL: Self-Directed Learning implementation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML
Status: RECRUITING
Conditions: Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia-2|Secondary Acute Myeloid Leukemia
Interventions: DRUG: unrelated umbilical cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Status: RECRUITING
Conditions: Chronic Fatigue Syndrome|Myalgic Encephalomyelitis
Interventions: DRUG: NAC 900mg/day|DRUG: NAC 3600mg/day|DRUG: NAC 0mg/day (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Immunogenicity, Safety and Tolerability of Adjuvanted and Non-Adjuvanted H2N3 Influenza Vaccines in Adults
Status: RECRUITING
Conditions: Influenza, Human|Infections|Respiratory Tract Infections|Virus Diseases|Infection Viral
Interventions: BIOLOGICAL: Low dose A/H2N3c + standard dose MF59|BIOLOGICAL: Intermediate dose A/H2N3c + standard dose MF59|BIOLOGICAL: High dose A/H2N3c + standard dose MF59|BIOLOGICAL: High dose A/H2N3c non-adjuvanted|BIOLOGICAL: Lowest dose A/H2N3c + high dose MF59|BIOLOGICAL: Low dose A/H2N3c + high dose MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiac Stem Cell Infusion in Patients With Ischemic CardiOmyopathy (SCIPIO)
Status: COMPLETED
Conditions: Coronary Artery Disease|Congestive Heart Failure
Interventions: BIOLOGICAL: Treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus CAMPATH in Patients With Relapsed/Refractory Low-Grade or Follicular, CD20-positive, B-cell NHL
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: CAMPATH (alemtuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Topical Citrullus Colocynthis Fruit Oil Efficacy in Treatment of Painful Peripheral Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: Topical Citrullus colocynthis fruit oil (1%)|DRUG: Topical vehicle oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Multi-sensory Rehabilitation on Upper Limb Function and Fatigue in Stroke
Status: RECRUITING
Conditions: Stroke|Ischemic
Interventions: OTHER: Cognitive multi-sensory Rehabilition|OTHER: selected traditional physical therapy program.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)
Status: COMPLETED
Conditions: Diet, Healthy|Obesity|Olfaction Disorders
Interventions: DIETARY_SUPPLEMENT: Fasting Mimicking Diet (FMD)|DIETARY_SUPPLEMENT: Routinary diet habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Effect of IMA-638 in Subjects With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: IMA-638|BIOLOGICAL: IMA-638|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Active Immunization of Sibling Bone Marrow Transplant Donors Against Purified Myeloma Protein of the Recipient Undergoing Allogeneic Bone Marrow Transplantation
Status: COMPLETED
Conditions: Graft vs Host Disease|Multiple Myeloma
Interventions: DRUG: Myeloma Immunoglobulin Idiotype Vaccine-KLH|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Esophagogastric Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: neoadjuvant Radiation plus SOX and PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Trauma|Adrenal Insufficiency|Pneumonia
Interventions: DRUG: Placebo|DRUG: Hydrocortisone Fludrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indomethacin for Tocolysis of Preterm Labor
Status: WITHDRAWN
Conditions: Preterm Labor
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Low-Cost Therapeutic Device in Managing Head and Neck Cancer Patients With Radiation-Related Trismus
Status: NOT_YET_RECRUITING
Conditions: Trismus|Head and Neck Cancer
Interventions: DEVICE: Trismus Device Prototype|OTHER: Questionnaires|OTHER: Mobile Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2)
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: zinc sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An RCT of Trauma Focused-Cognitive Behavioral Therapy With Sexually Exploited, War-affected Girls in the DRC
Status: COMPLETED
Conditions: Post-traumatic Stress Symptoms|Psychosocial Distress
Interventions: BEHAVIORAL: Trauma-Focused Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tolerability Between Two Allergy Drops
Status: UNKNOWN
Conditions: Allergic Conjunctivitis
Interventions: DRUG: alacaftadine and naphazoline HCl & pheniramine maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer
Status: COMPLETED
Conditions: Metastatic Melanoma|Metastatic Kidney Cancer
Interventions: DRUG: Natural Killer (NK) Lymphocytes|BIOLOGICAL: IL-2|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment for Anxiety Disorders
Status: COMPLETED
Conditions: Panic Disorder|Generalized Anxiety Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: Transdiagnostic Treatment (F-SET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Patellar Tendon Assessment
Status: UNKNOWN
Conditions: Patellofemoral Pain|Ultrasonography
Interventions: OTHER: 448kilohertz Capacitive Resistive Radiofrequency Stimulation in a Sporty Population.|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Identifying Risk Factors for Falls in Patients With a High Risk of Fracture Using Connected Insoles (FeetMe Monitor® Device)
Status: RECRUITING
Conditions: Fall|Fall Patients|Osteoporosis
Interventions: DEVICE: FeetMe® Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Safety and Efficacy of Venetoclax (GDC-0199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or Venetoclax Plus Rituximab in Participants With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma (fNHL)
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: DRUG: Venetoclax|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sugammadex: Effect on the Awareness Monitoring and Hemodynamics
Status: UNKNOWN
Conditions: Surgical Procedure, Unspecified
Interventions: DRUG: sugammadex|DRUG: Sugammadex 4 mg/kg|DRUG: Sugammadex 16mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS)
Status: RECRUITING
Conditions: KSHV Inflammatory Cytokine Syndrome (KICS)|KSHV|HHV-8
Interventions: DRUG: Zidovudine|DRUG: Liposomal Doxorubicin|DRUG: Valganiclovir|DRUG: Rituximab|OTHER: Standard Therapies|OTHER: Cohort 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inuline Supplement in Patients With Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Inuline, Choline and Silymarin|OTHER: diet restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress-induced Sleep Deficits and a Complementary Therapy
Status: COMPLETED
Conditions: Insomnia Due to Anxiety and Fear
Interventions: DIETARY_SUPPLEMENT: DHM|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Radiographic Assessment of Three Dimensional Mandibular Position Using Splint-less Patient Specific Implant
Status: RECRUITING
Conditions: Abnormality of Facial Skeleton
Interventions: DEVICE: mandibular saggital split osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: 131I-Omburtamab, in Recurrent Medulloblastoma and Ependymoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Medulloblastoma|Recurrent Ependymoma
Interventions: DRUG: Irinotecan|DRUG: Temozolomide|DRUG: Bevacizumab|DRUG: Omburtamab I-131|DRUG: Liothyronine|DRUG: SSKI|DRUG: Dexamethasone|DRUG: Antipyretic|DRUG: Antihistamine|DRUG: anti-emetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: darunavir/ritonavir then atazanavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 8 Weeks of MBSR Training on Neuroplasticity and Improvement of Attention, Memory and Well-Being
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress
Interventions: BEHAVIORAL: MBSR meditation|BEHAVIORAL: MBT training|BEHAVIORAL: Wellness|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Repetitive Transcranial Magnetic Stimulation (rTMS) as add-on Treatment for Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Cognition Disorders
Interventions: PROCEDURE: repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Brain Cancer
Interventions: DRUG: Arsenic Trioxide|PROCEDURE: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: PROCEDURE: Metabolic Challenge Admission|OTHER: CGM home test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cusatuzumab|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
Status: UNKNOWN
Conditions: Grain-Like Products|Postprandial Glucose|Plasma Insulin|Subjective Saturation Response|Healthy Individuals
Interventions: DIETARY_SUPPLEMENT: Flaxseed and Chia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Male Subjects
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Tedisamil sesquifumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder|Cigarette Smoking
Interventions: BEHAVIORAL: Telehealth Motivational Counseling|DRUG: Nicotine Replacement Product|DEVICE: National Institute on Drug Abuse (NIDA) Standardized Research Electronic Cigarette (SREC).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Sevirumab|DRUG: Foscarnet sodium|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Chidamide|DRUG: Venetoclax|DRUG: azacitidine|DRUG: Anthracyclines or anthraquinones|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mitoxantrone Hydrochloride Liposome Combined With Capecitabine in Patients With HER-2 Negative Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Mitoxantrone hydrochloride liposome|DRUG: Capecitabine|DRUG: Mitoxantrone hydrochloride liposome|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bridging the Gap - Tools for Finding Health, Mental Health and Wellness Resources for University and College Students
Status: COMPLETED
Conditions: Adolescent|Mental Health Wellness 1|Self Efficacy|Stigma, Social
Interventions: OTHER: Thought Spot|OTHER: Resource Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Elastic Therapeutic Tape on Biomechanical Changes of Knee Joint During Drop Vertical Jump in ACL Injuries
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: DEVICE: Kinesio tape|DEVICE: Control tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid Tumors
Status: TERMINATED
Conditions: PIK3CA Mutated Advanced Solid Tumors|PIK3CA Amplified Advanced Solid Tumors
Interventions: DRUG: BYL719|DRUG: AMG 479
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Brain Function Assessment Algorithm for mTBI/Concussion in College Athletes
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Concussion, Mild|Concussion, Brain|Concussion, Severe|Concussion, Intermediate
Interventions: DEVICE: BrainScope Ahead 200iD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tislelizumab and Metronomic Capecitabine as Maintenance in High-risk Locoregionally-advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: COMBINATION_PRODUCT: CCRT with Maintenance Tislelizumab and Metronomic Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro-Electrodes Implanted in a Human Nerve
Status: TERMINATED
Conditions: Amputations|Peripheral Nerve Injury|Spinal Cord Injury
Interventions: DEVICE: Utah Slanted Electrode Array
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Nivolumab and Ipilimumab Versus Chimiotherapy in First Line Treatment in PS 2 or Elderly in Advanced NSCLC Patients
Status: COMPLETED
Conditions: Advanced Non Small Cell Lung Cancer
Interventions: DRUG: Nivolumab + Ipilimumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Th1/Th2/Th17/TREG and TLRs Activation/KIR for COVID 19 Prediction of Outcome
Status: COMPLETED
Conditions: Disease, Viral|Cytokine Release Syndrome|TLRs
Interventions: DIAGNOSTIC_TEST: Cytokines measurement|DIAGNOSTIC_TEST: Cellular response|DIAGNOSTIC_TEST: TLRs activation measurement|DIAGNOSTIC_TEST: KIR phenotype evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a Multidisciplinary Care Management Program for High-risk Patients With Heart Failure (PROMIC)
Status: COMPLETED
Conditions: Heart Failure
Interventions: BEHAVIORAL: Care management program "PROMIC"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sensoril(Ashwaganhda)for Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar I Disorder|Bipolar II Disorder|Bipolar Disorder NOS
Interventions: DRUG: Sensoril|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of EF-022 in Adults With Recurrent Respiratory Papillomatosis (RRP)
Status: UNKNOWN
Conditions: Recurrent Respiratory Papillomatosis
Interventions: DRUG: EF-022 (Modified Vitamin D Binding Protein Macrophage Activator)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iTear Single-center, Open-label, Single-arm Study
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Disease|Dry Eye Syndromes|Dry Eye|Meibomian Gland Dysfunction
Interventions: DEVICE: iTEAR100 Neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Trials Which Assessed Consumption of Slowly Digestible Carbohydrates for 21 Days on Gastric Emptying Rates
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DIETARY_SUPPLEMENT: slowly digestible carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: TQB3616 Capsules Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer in Clinical Trail
Status: UNKNOWN
Conditions: HR-positive,HER2-negative in Advanced Breast Cancer
Interventions: DRUG: TQB3616 capsules|DRUG: TQB3616-matching placebo|DRUG: Fluvestrin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eltrombopag Phase III Study In Chinese Chronic ITP Patients
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic and Hepatitis C
Interventions: DRUG: eltrombopag|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Double-slot Brackets Versus Single-slot Brackets on the Rate of Canine Retraction
Status: RECRUITING
Conditions: Rate of Canine Retraction
Interventions: DEVICE: Double-slot brackets|DEVICE: Single-slot brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TREC Lifestyle Beyond Cancer Study in Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: BEHAVIORAL: Telemedicine Weight Management plus Wi-Fi Scale (Arm A)|BEHAVIORAL: Text for Diet (Text4Diet) Group (Arm B)|BEHAVIORAL: Enhanced Usual Care Group (Arm C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Prevention of Vasospasm in SAH Through CSF Treatment
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage|Subarachnoid Hemorrhage, Aneurysmal|Vasospasm, Cerebral|Aneurysmal Subarachnoid Hemorrhage
Interventions: OTHER: intravenous reinstallation of cerebrospinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Observational, Multicenter Study to Evaluate the Safety and Effectiveness of Hetrombopag in Patients With ITP or AA
Status: NOT_YET_RECRUITING
Conditions: Primary Immune Thrombocytopenia|Aplastic Anemia
Interventions: DRUG: hetrombopag
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY3337641 in Japanese and Caucasian Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3337641|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serum TWEAK Levels in Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Isotretinoin|DIAGNOSTIC_TEST: ELISA Assays of Serum TWEAK.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction and Evaluation of Anlotinib Treatment Response Using Contrast Enhanced Ultrasound PPGL Patients
Status: RECRUITING
Conditions: Pheochromocytoma, Metastatic|Ultrasonography|Paraganglioma, Malignant|Pheochromocytoma Malignant
Interventions: DIAGNOSTIC_TEST: Contrast-enhanced ultrasound(CEUS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: RADIATION: Radiation|DRUG: Chemotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Randomised Controlled Trial of Early Vitrectomy for Post-operative Exogenous Endophthalmitis
Status: RECRUITING
Conditions: Endophthalmitis Postoperative Acute
Interventions: PROCEDURE: Vitrectomy|PROCEDURE: Intravitreal antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Bile Duct Carcinoma|Stage II Esophageal Cancer AJCC v7|Stage II Pancreatic Cancer AJCC v6 and v7|Stage IIA Esophageal Cancer AJCC v7|Stage IIA Pancreatic Cancer AJCC v6 and v7|Stage IIB Esophageal Cancer AJCC v7|Stage IIB Pancreatic Cancer AJCC v6 and v7|Stage III Colon Cancer AJCC v7|Stage III Esophageal Cancer AJCC v7|Stage III Gastric Cancer AJCC v7|Stage III Liver Cancer|Stage III Pancreatic Cancer AJCC v6 and v7|Stage III Rectal Cancer AJCC v7|Stage III Small Intestinal Cancer AJCC v7|Stage IIIA Colon Cancer AJCC v7|Stage IIIA Esophageal Cancer AJCC v7|Stage IIIA Gastric Cancer AJCC v7|Stage IIIA Rectal Cancer AJCC v7|Stage IIIA Small Intestinal Cancer AJCC v7|Stage IIIB Colon Cancer AJCC v7|Stage IIIB Esophageal Cancer AJCC v7|Stage IIIB Gastric Cancer AJCC v7|Stage IIIB Rectal Cancer AJCC v7|Stage IIIB Small Intestinal Cancer AJCC v7|Stage IIIC Colon Cancer AJCC v7|Stage IIIC Esophageal Cancer AJCC v7|Stage IIIC Gastric Cancer AJCC v7|Stage IIIC Rectal Cancer AJCC v7|Stage IV Colon Cancer AJCC v7|Stage IV Esophageal Cancer AJCC v7|Stage IV Gastric Cancer AJCC v7|Stage IV Liver Cancer|Stage IV Pancreatic Cancer AJCC v6 and v7|Stage IV Rectal Cancer AJCC v7|Stage IV Small Intestinal Cancer AJCC v7|Stage IVA Colon Cancer AJCC v7|Stage IVA Liver Cancer|Stage IVA Rectal Cancer AJCC v7|Stage IVB Colon Cancer AJCC v7|Stage IVB Liver Cancer|Stage IVB Rectal Cancer AJCC v7
Interventions: RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Ropidoxuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focal Microvibration and Chronic Lumbosacral Radicular Pain
Status: NOT_YET_RECRUITING
Conditions: Pain, Chronic|Lumbosacral Radiculopathy|Radicular; Neuropathic
Interventions: DEVICE: Equistasi®|DEVICE: Sham|DRUG: Gabapentin; Pregabalin; Duloxetine; Amitriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MINIject Glaucoma Implant in European Patients
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Glaucoma Eye|Intraocular Pressure
Interventions: DEVICE: Glaucoma device implantation in a stand-alone procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lanabecestat|DRUG: Simvastatin|DRUG: Midazolam|DRUG: Midazolam|DRUG: Donepezil|DRUG: Lanabecestat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of PF-05175157 in Healthy Volunteers and Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05175157 or Placebo|DRUG: PF-05175157 or Placebo|DRUG: PF-05175157 or Placebo|DRUG: PF-05175157 or Placebo|DRUG: PF-05175157 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reducing Children's Racial Biases Via a Parent-Led Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Racial Bias
Interventions: BEHAVIORAL: EmBARK|BEHAVIORAL: Popular guidance|BEHAVIORAL: Practice first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cortical Plasticity Assessment in Athletes With a History of Concussion
Status: TERMINATED
Conditions: Concussion
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Addressing Psychosocial Comorbidities in HIV Treatment and Prevention 2b
Status: ENROLLING_BY_INVITATION
Conditions: Medication Adherence|Mental Health Issue
Interventions: BEHAVIORAL: CBT for Syndemics and Adherence Factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stoma Care Education on the Knowledge and Skill Levels of Pediatric Surgery Nurses
Status: RECRUITING
Conditions: Stoma Ileostomy|Stoma Colostomy|Nurse's Role|Pediatric Surgery
Interventions: OTHER: education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines
Status: RECRUITING
Conditions: Cardiomyopathy|Heart Failure|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|OTHER: Laboratory Biomarker Analysis|DRUG: Mesenchymal Stem Cell Transplantation|DRUG: Mesenchymal Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroplasty Versus Internal Fixation for Undisplaced Femoral Neck Fracture
Status: ACTIVE_NOT_RECRUITING
Conditions: Undisplaced Fracture|Femoral Neck Fractures|Internal Fixation; Complications|Arthroplasty Complications
Interventions: PROCEDURE: Arthroplasty|PROCEDURE: Internal fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of 10XB-101 Injections in Adult Subjects With Extra Fat Under the Chin ("Double Chin")
Status: COMPLETED
Conditions: Submental Fat
Interventions: DRUG: 10XB-101 Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sunvozertinib Combined With Anlotinib in Local Advanced or Metastatic Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: NSCLC
Interventions: DRUG: Sunvozertinib combination with Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Exercise Substrate Oxidation, Appetite and Energy Intakes in Overweight/Obese Postmenopausal Women (EScAPE)
Status: COMPLETED
Conditions: Overweight|Postmenopausal
Interventions: OTHER: Moderate Intensity Continuous Exercise|OTHER: High-Intensity Interval Exercise (1)|OTHER: High-Intensity Interval Exercise (2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)
Status: RECRUITING
Conditions: Pulmonary Arterial Hypertension|Healthy
Interventions: RADIATION: TSPO PET scan (11C-PBR28)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Explorations of the Benefits of the ZeroG TRiP System to Improve Balance in Patients Following Stroke
Status: COMPLETED
Conditions: Stroke|Balance; Distorted
Interventions: DEVICE: Body weight support system control group|DEVICE: Body weight support system with balance perturbations
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot
Status: ENROLLING_BY_INVITATION
Conditions: Wound Heal|Diabetic Foot Ulcer
Interventions: PROCEDURE: high ankle block|PROCEDURE: general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Long Term Safety and Efficacy of UX007 in Participants With Glucose Type 1 Deficiency Syndrome (Glut1 DS)
Status: TERMINATED
Conditions: Glucose Transporter Type 1 Deficiency Syndrome
Interventions: DRUG: UX007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Blinatumomab in Treating Patients With Relapsed or Refractory B Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Adult B Acute Lymphoblastic Leukemia|Philadelphia Chromosome Positive
Interventions: BIOLOGICAL: Blinatumomab|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autoreactivity Threshold Analysis in Lupus and Immune Thrombocytopenia (Checkpoints ITP and SLE)
Status: UNKNOWN
Conditions: Immune Thrombocytopenia (ITP)|Systemic Lupus Erythematosus (SLE)
Interventions: OTHER: Bliss-Believe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NovoTTF-100A With Bevacizumab (Avastin) in Patients With Recurrent Glioblastoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Tumor
Interventions: BIOLOGICAL: Bevacizumab|DEVICE: NovoTTF-l00A|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "ALCO-VR": Virtual Reality Cue Exposure Therapy for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Virtual Reality Cue Exposure Therapy|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicentric Randomized Study of Glivec® in Advanced GIST Expressing C-kit: Interruption After 5 Years vs Maintenance
Status: COMPLETED
Conditions: Sarcoma|Gastro-intestinal Stromal Tumors (GIST)
Interventions: DRUG: interruption of Glivec®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess HDL-C Increase And Non-HDL Lowering Effect Of Torcetrapib/Atorvastatin Vs. Fenofibrate
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Torcetrapib/Atorvastatin|DRUG: Fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of ASC-101 in Patients With Hematologic Malignancies Who Receive Dual-cord Umbilical Cord Blood Transplantation
Status: UNKNOWN
Conditions: Blood And Marrow Transplantation|Leukemia|Lymphoma|Transplantation Infection|Myelodysplastic Syndrome (MDS)|Non-Hodgkin's Lymphoma (NHL)|Hodgkin's Lymphoma
Interventions: DRUG: Fludarabine, Clofarabine, Busulfan, ATG, TBI (Myeloablative)|DRUG: Fludarabine, Melphalan, ATG (Reduced Intensity)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APOLLO 11, Consortium of Italian Centers Involved in Treatment of Patients With Lung Cancer Treated With Innovative Therapies: Real World Data and Translational Reaserch
Status: RECRUITING
Conditions: NSCLC|Cancer|Lung Cancer|Adenocarcinoma of Lung|Squamous Cell Lung Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Androgen Receptor Signaling Inhibitors on 68Ga-PSMA-11 PET/CT Imaging in Patients With Castration-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68 Gozetotide|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC