pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Safety, Effectiveness and Quality of Life Outcomes Between Labeled Versus "Treat and Extend" Regimen in Turkish Patients With Choroidal Neovascularisation Due to Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Sativex® (Treatment A)|DRUG: Sativex® and fluconazole concomitantly (Treatment B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: What Amount of Stress is Enough for a Successful Conception?
Status: UNKNOWN
Conditions: In Vitro Fertilization|Stress|Midazolam Adverse Reaction|Stress, Emotional
Interventions: DRUG: Midazolam 7.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polio End-game Strategies - Poliovirus Type 2 Challenge Study
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: IPV|BIOLOGICAL: bOPV|BIOLOGICAL: bOPV and IPV|BIOLOGICAL: bOPV and IPV and IPV2|BIOLOGICAL: tOPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Prone Position Training on Pulmonary Complications in Patients Undergoing Laparoscopic Colorectal Surgery
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Complication
Interventions: BEHAVIORAL: Prone Position Training|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE)
Status: NOT_YET_RECRUITING
Conditions: Lymphedema|Fibrosis
Interventions: DRUG: Pravastatin|DRUG: Pentoxifylline|DRUG: Tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treg Cells for AGVHD in Non-myeloablative UCB Transplant
Status: WITHDRAWN
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: T Regulatory cells|DRUG: Fludarabine|DRUG: Cyclophosphamide|RADIATION: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity of Quadrivalent Meningococcal Conjugate Vaccine in Frequent Platelets Donors
Status: ACTIVE_NOT_RECRUITING
Conditions: Preventive Immunization; Meningitis
Interventions: BIOLOGICAL: Menactra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Decitabine/Cedazuridine|DRUG: Magrolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of REMD-477 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes
Interventions: BIOLOGICAL: REMD-477
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Controlled Clinical Trials, on Adult Patients With T-lymphoblastic Lymphoma Treated With Intensive Chemo/Radiotherapy or Intensive Chemotherapy Followed by Transplant. Evaluation of Clinical, Anatomy -Pathological Parameters
Status: UNKNOWN
Conditions: Lymphoblastic Lymphoma
Interventions: OTHER: Latest generation chemotherapies for T-LBL + transplant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: corticosteroid solution with lidocaine containing parabens.|DRUG: corticosteroid solution with lidocaine containing no paraben
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Montelukast in Veterans With Gulf War Illness
Status: NOT_YET_RECRUITING
Conditions: Gulf War Syndrome
Interventions: DRUG: Montelukast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the 4-channel Sequential NMES for the Treatment of Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Apnea
Interventions: DEVICE: 4 channel Electrical Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Investigate the Influence of the Homeopathic Remedy Naja-comp on Stroke Therapy in Geriatric Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Naja-comp.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimers Disease
Interventions: BIOLOGICAL: CAD106 Immunotherapy|OTHER: Placebo to CAD106|DRUG: CNP520|OTHER: Placebo to CNP520|OTHER: Alum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation of S1 Capsule for Stage Ⅱ-ⅢA Non-small Cell Lung Cancer After Complete Resection
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer Stage Ⅱ|Non-small Cell Lung Cancer Stage ⅢA
Interventions: DRUG: S1 capsule|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous (IV) Nitroglycerin for Versions in Nulliparous Women
Status: COMPLETED
Conditions: Breech Presentation|Complication of Pregnancy
Interventions: DRUG: IV Nitroglycerin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Immunoregulatory Dendritic Cells for Type 1 Diabetes Therapy
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Immunoregulatory Dendritic Cells|OTHER: Placebo Comparator: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effect of Systemic Stress on Measured Blood Concentrations of 25 (OH) Vitamin D
Status: COMPLETED
Conditions: Cardiovascular Disease|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides
Status: COMPLETED
Conditions: Refractory Mycosis Fungoides
Interventions: DRUG: Aminolevulinic Acid Hydrochloride|DRUG: Photodynamic Therapy|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virgin Coconut Oil Oral Supplementation for Leprosy Patients
Status: WITHDRAWN
Conditions: Hansen's Disease
Interventions: OTHER: Multi-Drug Therapy (Novartis Ⓡ)|DIETARY_SUPPLEMENT: Virgin Coconut Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of the Results of Intense Pulsed Light Treatment Previously to Laser Refractive Surgery
Status: RECRUITING
Conditions: Meibomian Gland Dysfunction|Blepharitis
Interventions: DEVICE: Study group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: HTX-011 Administration Study in Planned Caesarean Section Procedure
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: HTX-011|DRUG: HTX-011|DEVICE: Luer Lock Applicator|DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid as an Intervention in Placenta Previa
Status: COMPLETED
Conditions: Interventional Drug in Placenta Previa
Interventions: DRUG: Tranexamic acid injection|OTHER: Glucose water 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Rhomboid Intercostal Subserratus Plane Block vs Erector Spinae Plane Block in Open Nephrectomy
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Rhomboid intercostal subserratus plane block|PROCEDURE: Erector spinae plane block|PROCEDURE: Thoraccic Epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Restoration of Chronotropic Competence in Heart Failure Patients With Normal Ejection Fraction
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: Insignia Plus / Ultra (Guidant/Boston Scientific)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azithromycin for Children Hospitalized With Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line EXL01 With Nivolumab and FOLFOX for PD-L1 CPS ≥5 Metastatic Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Nivolumab|DRUG: FOLFOX regimen|BIOLOGICAL: EXL01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Winged Biliary Stent Patency in Patients With Benign Biliary Obstruction
Status: COMPLETED
Conditions: Biliary Stricture
Interventions: DEVICE: Winged biliary stent (ViaDuct™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of of Olodaterol and Ketoconazole
Status: COMPLETED
Conditions: Healthy|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: BI 1744|DRUG: BI 1744|DRUG: Ketoconazole|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers
Status: COMPLETED
Conditions: Vaginal Cancer|Cervical Cancer|Anal Cancer|Penile Cancer|Oropharyngeal Cancer
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: E6 TCR|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
Status: COMPLETED
Conditions: Healthy, no Evidence of Disease|Obesity|Weight Changes
Interventions: OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|OTHER: survey administration|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Discrimination and Religious Experiences of Adult Muslimahs in Salaat
Status: RECRUITING
Conditions: Stress, Psychological|Control
Interventions: BEHAVIORAL: Salaat|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormonal Factors in the Treatment of Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Eating Disorder|Anxiety|Depression
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Quality of Life Following Dysport Treatment in Post-stroke Spasticity of the Arm
Status: COMPLETED
Conditions: Cerebrovascular Accident|Muscle Spasticity
Interventions: BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Anti-Angiogenic Drug Combination Tl-118 for Pancreatic Cancer Patients Who Are Starting Gemcitabine Treatment
Status: UNKNOWN
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: TL-118|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chitosan Phonophoresis On Cubital Tunnel Syndrome
Status: COMPLETED
Conditions: Cubital Tunnel Syndrome|Ulnar Nerve Entrapment at Elbow|Ulnar Nerve Compression|Ulnar Nerve Entrapment Syndrome
Interventions: DEVICE: Chitosan Phonophoresis|DEVICE: Therapeutic Ultrasound|DEVICE: Splinting|OTHER: Neural mobilization exercises of the ulnar nerve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
Status: COMPLETED
Conditions: Tobacco Cessation
Interventions: BEHAVIORAL: Motivational interviewing|BEHAVIORAL: Smoking cessation counseling|BEHAVIORAL: Navigation to smoking cessation resources|BEHAVIORAL: Social support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Investigation to Identify if Dame Product's "DLM" Works to Improve Sexual Desire and Mood in Females
Status: COMPLETED
Conditions: Sexual Desire Disorder
Interventions: DIETARY_SUPPLEMENT: DLM - Test product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Onychomycosis With Loceryl (Amorolfine) Nail Lacquer 5% Versus Ciclopirox Nail Lacquer
Status: COMPLETED
Conditions: Foot Dermatoses
Interventions: DRUG: Loceryl NL|DRUG: Ciclopirox NL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow-Derived Mononuclear Cell Transplantation in Accelerating Tissue Expansion and Skin Regeneration
Status: UNKNOWN
Conditions: Tissue Expansion;|Skin Regeneration;|Reconstruction;|Bone Marrow Mononuclear Cells
Interventions: PROCEDURE: Autologous bone marrow mononuclear cells|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: CMF regimen|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: fluorouracil|DRUG: ifosfamide|DRUG: methotrexate|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Study of Targeted NY-ESO-1 T Cell Receptor (TCR) Genetic Modified Autologous T Cells Treatment of Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Malignant Solid Tumors
Interventions: OTHER: TCR - T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sperm Selection for Infertility Treatment (SSA)
Status: UNKNOWN
Conditions: Infertility
Interventions: DEVICE: Sperm Selection Assay|OTHER: Attractant Substance|PROCEDURE: ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Tolerability of Oral Ziprasidone in Children and Teens With Psychotic Disorders
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Schizoaffective Disorder
Interventions: DRUG: Ziprasidone|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ShuntCheck-Micro-Pumper Pediatric Clinical Outcomes Study
Status: UNKNOWN
Conditions: Suspected CSF Shunt Obstruction
Interventions: DEVICE: ShuntCheck-Micro-Pumper (SCMP)|DEVICE: Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: B-type Natriuretic Peptide for Acute Shortness of Breath EvaLuation (BASEL) Study - Private Practice
Status: COMPLETED
Conditions: Dyspnea
Interventions: OTHER: BNP measurement|OTHER: Clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Solifenacin Succinate and Tamsulosin Hydrochloride OCAS in Males With Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: Placebo tamsulosin hydrochloride OCAS 0.4 mg|DRUG: Placebo FDC tamsulosin hydrochloride/solifenacin succinate 0.4 mg/6 mg|DRUG: Placebo FDC tamsulosin hydrochloride/solifenacin succinate 0.4 mg/9 mg|DRUG: tamsulosin hydrochloride OCAS 0.4 mg|DRUG: tamsulosin hydrochloride/solifenacin succinate fixed dose combination (0.4 mg/6 mg)|DRUG: tamsulosin hydrochloride/solifenacin succinate fixed dose combination (0.4 mg/9 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indocanine Green as Tracer for Lymph Nodes Dissection in Station 253
Status: UNKNOWN
Conditions: Rectal Carcinoma|Sigmoid Colon Carcinoma
Interventions: PROCEDURE: lymph nodes dissection at 253 station assisted by ICG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Healthy Female Participants to Investigate the Effect of JNJ-56136379 at Steady-state on the Single-dose Pharmacokinetics of Ethinylestradiol and Drospirenone (Oral Contraceptive) and on the Single-dose Pharmacokinetics of Midazolam (Probe Substrate for Cytochrome P450 3A4)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Drospirenone/Ethinylestradiol|DRUG: Midazolam|DRUG: JNJ-56136379
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Bioimaging Trial of DS-8895a in Patients With Advanced EphA2 Positive Cancers
Status: COMPLETED
Conditions: Malignant Solid Tumor|Metastatic EphA2 Positive Cancer
Interventions: DRUG: DS-8895a 1 mg/kg|DRUG: DS-8895a 3 mg/kg|DRUG: DS-8895a 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention
Status: TERMINATED
Conditions: Angina Pectoris
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Replacement of Vitamin D in Patients With Active Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Cholecalciferol|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Desmopressin Acetate 0.2 mg Tablets, Fasting
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Desmopressin Acetate 0.2 mg Tablets|DRUG: DDAVP® 0.2 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Ondansetron in the Prevention of Hypotension in Patients Undergoing Spinal Anesthesia
Status: UNKNOWN
Conditions: Hypotension
Interventions: DRUG: Prophylactic ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of CPAP on Ventricular Function Modifications
Status: WITHDRAWN
Conditions: Heart Failure, Congestive
Interventions: DEVICE: CPAP (Continuous Positive Airway Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of Olpasiran in Participants With Various Degrees of Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Olpasiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Physical Training in iNPH
Status: COMPLETED
Conditions: Hydrocephalus, Normal Pressure
Interventions: OTHER: High Intensive Functional Exercise (HIFE)|OTHER: Physical training advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of NT-proBNP on MACEs After Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|ST-segment Elevation Myocardial Infarction (STEMI)|Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)|Major Adverse Cardiac Events
Interventions: DIAGNOSTIC_TEST: N-terminal pro-B-type natriuretic peptide (NT-proBNP)|DIAGNOSTIC_TEST: high sensitive cardiac troponin T (hs-cTnT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pegtibatinase as an Enzyme Therapy for Patients With Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Homocystinuria
Interventions: DRUG: Pegtibatinase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Core Binding Factor Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Therapy-Related Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Daunorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma
Status: COMPLETED
Conditions: High Grade Glioma
Interventions: PROCEDURE: DNA methylation analysis|PROCEDURE: polymerase chain reaction|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Combined Effects Of Sensory Integration And Vestibular Exercises On Post-Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Post Stroke
Interventions: OTHER: Sensory Integration and Vestibular Exercise with Routine Physical Therapy|OTHER: Vestibular Exercise with Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Implantation of CRENEOUS ENTERPRISE 2 Intracranial Stent in Participants With Severe Symptomatic Intracranial Atherosclerotic Stenosis
Status: RECRUITING
Conditions: Intracranial Atherosclerosis
Interventions: DEVICE: CERENOVUS ENTERPRISE 2 Intracranial Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Postural Control in Patients With Respiratory Disease at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Renal Protection During Deceased Brain Dead Donor Kidney Transplantation - A Prospective, Randomized Trial
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: Desflurane balanced anesthesia|DRUG: Propofol total intravenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Hydroxyzine for Patients With Panic Disorder
Status: NOT_YET_RECRUITING
Conditions: Panic Disorder
Interventions: DRUG: Hydroxyzine|DRUG: Escitalopram Oxalate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin Gel as an Adjunct to Xenograft in the Surgical Management of Intrabony Periodontal Defects
Status: COMPLETED
Conditions: Periodontal Bone Loss
Interventions: DRUG: particulate xenograft + erythropoietin gel.|COMBINATION_PRODUCT: particulate xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells
Status: COMPLETED
Conditions: Hodgkin Disease|Non-Hodgkin Lymphoma|Multiple Myeloma|Bacteremia
Interventions: DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sympathetic Mapping/ Ablation of Renal Nerves Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DEVICE: SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Non-Randomised Clinical Trial to Investigate the BeGraft Aortic Stent Graft System and the BeGraft Peripheral Stent Graft System Treating Aortic-iliac Occlusive Disease
Status: NOT_YET_RECRUITING
Conditions: Aorto-iliac Occlusive Disease
Interventions: DEVICE: endovascular intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Monitoring and Support for Patients With Schizophrenia, Schizoaffective or Bipolar Disorder on Adherence
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: BEHAVIORAL: intervention for improvement of adherence|BEHAVIORAL: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-M05D1 in Patients With Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: BL-M05D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Prefrontal and Medial Temporal Neuronal Responses to Algorithmic Cognitive Variables in Epilepsy Patients
Status: RECRUITING
Conditions: Epilepsy
Interventions: DEVICE: NEUROPACE RNS SYSTEM|BEHAVIORAL: EMU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Subjective Observational Study of Patients Using Transdermal Cream Medication And/Or Transdermal Patches With Or Without Oral Non-Narcotic Medications
Status: UNKNOWN
Conditions: Pain, Chronic|Pain, Joint|Pain Syndrome
Interventions: COMBINATION_PRODUCT: transdermal cream and or patch
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV
Interventions: DRUG: Dolutegravir|DRUG: Emtricitabine/Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
Status: ENROLLING_BY_INVITATION
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Sprint-Intensity Interval Training with Telecoaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis
Status: COMPLETED
Conditions: Atrial Fibrillation|End Stage Renal Failure on Dialysis
Interventions: DRUG: Warfarin|DRUG: Apixaban|OTHER: No oral anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACT to Prevent Eating Disorders: Evaluating a Gamified Prevention Program
Status: UNKNOWN
Conditions: High Risk for Eating Disorder|Eating Disorders in Adolescence|Acceptance Processes
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Radiologic Assessment in Complete Mesocolic Excision for Right Colon Cancer (RACOMERC)
Status: UNKNOWN
Conditions: Right-sided Colon Cancer
Interventions: PROCEDURE: Laparoscopic right colonic resection with Complete Mesocolic Excision (CME)|RADIATION: 3D CT angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Tiszasüly and Kolop Mud-pack Therapy in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Tiszasüly hot mud-pack therapy|OTHER: Kolop mud-pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Intellectual Disability
Interventions: DIAGNOSTIC_TEST: Clinical evaluation|DIAGNOSTIC_TEST: Neuropsychological evaluation|DIAGNOSTIC_TEST: Neurophysiological evaluation|DIAGNOSTIC_TEST: Genetic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of LAMA Added to ICS in Treatment of Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: CHF 5259 12.5 µg|DRUG: CHF 5259 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TeleRehabilitation in Hypertension
Status: COMPLETED
Conditions: Hypertension|Pre-hypertension|Healthy
Interventions: OTHER: Isometric handgrip exercise|OTHER: Aerobic endurance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiviral Activity and Safety of Mifepristone at 2 Doses in HIV-1 Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: VGX-410 (Mifepristone)|DRUG: Placebo for VGX-410 (Mifepristone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of SHR-1316 and Fluzoparib（SHR-3162） in Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: 1.Experimental: A (Part 1): Fluzoparib and SHR -1316|DRUG: 2.Experimental: B (Part 1): Fluzoparib and SHR -1316|DRUG: 3.Experimental: C (Part 2): Fluzoparib and SHR -1316 Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Delirium in Patients Anaesthetised With Isoflurane and Desflurane During Spinal Surgery
Status: COMPLETED
Conditions: Postoperative Delirium
Interventions: DRUG: Isoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Bioequivalence Study of Amlodipine Besylate/Benazepril HCl 10 mg/40 mg Capsules of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Amlodipine Besylate/Benazepril HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Transcutaneous Acupoint Electrical Stimulation (TAES) on Postoperative Cough in Lung Cancer
Status: RECRUITING
Conditions: Postoperative Cough|Lung Cancer
Interventions: OTHER: Transcutaneous Acupoint Electrical Stimulation (TAES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Family-Based Treatment for Adolescent Methamphetamine Use
Status: COMPLETED
Conditions: Behavior and Mental Disorders|Methamphetamine Disorders
Interventions: BEHAVIORAL: Adolescent Methamphetamine Treament (AMT)|BEHAVIORAL: Functional Family Therapy (FFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Concentration Local Anesthesia Fascia Iliaca Block for Total Hip Arthroplasty
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Hip
Interventions: OTHER: Low Concentration Local Anesthetic Fascia Iliaca Compartment Block|OTHER: High Concentration Local Anesthetic Fascia Iliaca Compartment Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biodex Sit2Stand for Individuals With Cardiac Disease
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Frail Elderly Syndrome|Heart Failure
Interventions: BEHAVIORAL: Exercise using the Biodex Sit2Stand Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Health Diary on Self-management in Adolescent Patients With Fixed Orthodontic Appliance
Status: RECRUITING
Conditions: Oral Hygiene|Self-Management
Interventions: BEHAVIORAL: Health Diary Program|BEHAVIORAL: Traditional Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Core Body Temperature When Using Forced Air Warming or an Active Blanket to Prevent Perioperative Hypothermia
Status: COMPLETED
Conditions: Inadvertent Perioperative Hypothermia|Preoperative Anxiety Experienced by the Patient
Interventions: DEVICE: Active self warming blanket|DEVICE: Forced air warming device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Superficial Basal Cell Carcinoma Treatment With Topical Photodynamic Therapy With Fractionated 5-aminolevulinic Acid 20% Versus Two Stage Methylaminolevulinate
Status: UNKNOWN
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: Methylaminolevulinate PDT in 2 sessions|DRUG: Fractionated 5-aminolevulinic acid hydrochloride 20% gel PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anesthesia Maintenance Methods on Long-term Survival
Status: COMPLETED
Conditions: Aged|Neoplasms|Surgical Procedure, Operative|Anesthesia, Inhalation|Anesthesia, Intravenous|Survival
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alvocidib Biomarker-driven Phase 2 AML Study
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Alvocidib|DRUG: Cytarabine|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo Compared to "Standard of Care" Basal Insulin in Patients Already Using Basal Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: insulin glargine (U300)|DRUG: insulin glargine (U100)|DRUG: NPH insulin|DRUG: insulin detemir|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Counterstrain Technique on Muscle Stiffness and Pain on Trapezius Tender Points in Medical Students
Status: COMPLETED
Conditions: Counterstrain|MyotonPRO|Tender Points
Interventions: OTHER: Counterstrain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NNC-0156-0000-0009 in Haemophilia B Patients
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia B
Interventions: DRUG: nonacog beta pegol|DRUG: nonacog beta pegol|DRUG: nonacog beta pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Possible Efficacy and Safety of Diosmin and Hesperidin Combined Therapy in Patients With Helicobacter Pylori Infection
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Placebo|DRUG: Daflon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Oligometastatic Renal Cell Carcinoma
Status: SUSPENDED
Conditions: Metastatic Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Effects of CAL-263 in Subjects With Allergic Rhinitis Exposed to Allergen in an Environmental Chamber
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: CAL-263|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of L-NDDP (Aroplatin) in Patients With Advanced Solid Malignancies or B-Cell Lymphoma
Status: COMPLETED
Conditions: Malignancies|B-Cell Lymphoma
Interventions: DRUG: Aroplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2010-2011 Trivalent Influenza Vaccine (TIV) in Pregnant Women
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With Fosamprenavir
Status: COMPLETED
Conditions: Chronic HIV Infection|HCV Coinfection
Interventions: DRUG: Fosamprenavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Care Brief Mindfulness Training for Veterans With PTSD
Status: COMPLETED
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Primary Care Brief Mindfulness Training|BEHAVIORAL: PTSD Psychoeducational Class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration and Virtual Reailtry on Quadriceps Strength and Activity of Daily Living in Children With Burn
Status: COMPLETED
Conditions: Whole Body Vibration|Virtual Reality
Interventions: DEVICE: whole bady vibration and virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of Vi-sealer
Status: RECRUITING
Conditions: Benign Gynecologic Neoplasm
Interventions: DEVICE: Vi-Sealer|DEVICE: Ligasure|DEVICE: Other AHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms|Fallopian Tube Neoplasms
Interventions: DRUG: Trabectedin|DRUG: DOXIL|DRUG: Dexamethasone|DRUG: DOXIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Low Bone Mass With Vibration Therapy in Adolescent Idiopathic Scoliosis (AIS)
Status: COMPLETED
Conditions: Scoliosis|Bone Diseases, Metabolic
Interventions: DEVICE: Vibration Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise as Intervention in Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: BEHAVIORAL: Exercise Training as Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By Surgery
Status: TERMINATED
Conditions: Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer
Interventions: DRUG: vorinostat|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neurologic Development of Temporal Voice Area (TVA) in Deaf Infant
Status: COMPLETED
Conditions: Profound Congenital Deaf Children Implanted
Interventions: PROCEDURE: fNIRS (Functional Near Infrared Spectroscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE