pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)
Status: RECRUITING
Conditions: Stage II Nasopharyngeal Carcinoma AJCC v8|Stage III Nasopharyngeal Carcinoma AJCC v8|Stage IV Nasopharyngeal Carcinoma AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Chest Radiography|DRUG: Cisplatin|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|OTHER: Electronic Health Record Review|OTHER: Fluciclovine F18|DRUG: Gemcitabine|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Insomnia Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Self-Managed Online Treatment|BEHAVIORAL: Therapist-Assisted Online Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Versus Medical Treatment for the Pelvic Congestion Syndrome
Status: UNKNOWN
Conditions: Pelvic Congestive Syndrome|Pelvic Varices|Venous Disease
Interventions: DEVICE: Medtronic® Concerto® detachable coil system|PROCEDURE: sclerosis|DRUG: Diosmin / Hesperidin|DRUG: Ibuprofen 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Erlotinib [Tarceva] as Monotherapy or Intermittent Dosing With Docetaxel in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer. (TALISMAN)
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: docetaxel|DRUG: erlotinib [Tarceva]|DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Finding Barriers and Designing Solutions to Promote Women s Cancer Screening in South Africa
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: OTHER: Semi-structured focus group discussions - Women|OTHER: semi-structured focus groups discussions - Men|OTHER: In-depth key stakeholders interviews|OTHER: Discrete Choice Experiment - Women|OTHER: Development and User Pre-testing Workshops
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunotherapy in Intractable Cryptogenic Epilepsy Patients With Autoimmune Antibody
Status: UNKNOWN
Conditions: Epilepsy, Unspecified, Intractable
Interventions: OTHER: IVIG|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Study to Investigate the Effect of Coadministration of EDP-305 on the PK of a Combined Oral Contraceptive in Healthy Female Subjects
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: EDP-305|DRUG: Oral Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Desvenlafaxine in Treating Major Depressive Disorder.
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release Tablet , Duloxetine Hydrochloride Enteric-coated Capsule Placebo|DRUG: Desvenlafaxine Succinate Sustained-Release Tablet Placebo, Duloxetine Hydrochloride Enteric-coated Capsule|DRUG: Duloxetine Hydrochloride Enteric-coated Capsule Placebo|DRUG: Duloxetine Hydrochloride Enteric-coated Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOFT- Stereotactic Ablative Radiotherapy of Infra-diaphragmatic Soft Tissue Metastases
Status: UNKNOWN
Conditions: Solid Tumor|Oligometastases|Soft Tissue Disease
Interventions: RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uncovering an Electrical Biomarker for Freezing of Gait in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep brain stimulation|OTHER: Electroencephalography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: SonoVue®-Enhanced Ultrasound Versus Unenhanced US for Focal Liver Lesion Characterization
Status: COMPLETED
Conditions: Liver Neoplasms
Interventions: DRUG: SonoVue-enhanced ultrasound|OTHER: Unenhanced ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Imatinib Mesylate in Treating Patients With Primary Gastrointestinal Stromal Tumor That Has Been Completely Removed By Surgery
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pentoxifylline and Rifaximin Combination in Pentoxifylline Refractory Clinical and Subclinical Hepatopulmonary Syndrome
Status: UNKNOWN
Conditions: Hepatopulmonary Syndrome
Interventions: DRUG: pentoxifylline and rifaximin|DRUG: Pentoxifylline and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Double-blind Parallel Trial to Evaluate Equivalence in Efficacy and Safety of HD203 and Enbrel in RA Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Etanercept|BIOLOGICAL: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Sargramostim Following Chemotherapy in Previously Untreated Aggressive Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: keyhole limpet hemocyanin|BIOLOGICAL: sargramostim|BIOLOGICAL: tumor cell-based vaccine therapy|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: mitoxantrone hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Janssen Ad26.CoV2.S Vaccine Booster in Kidney Transplant Recipients
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant Recipient
Interventions: BIOLOGICAL: Janssen Ad26.CoV2.S Vaccine|OTHER: Reduction in Immunosuppression Medication|OTHER: Maintenance in Immunosuppression Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Randomized Trial Comparing GA101 and Rituximab in Untreated Low Tumor Burden Indolent Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Indolent Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Arm A: Rituximab|BIOLOGICAL: Arm B: GA101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Ocrelizumab in Patients With Nephritis Due to Systemic Lupus Erythematosus (BELONG)
Status: TERMINATED
Conditions: Lupus Nephritis|Systemic Lupus Erythematosus
Interventions: DRUG: Corticosteroids|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil|DRUG: Ocrelizumab|DRUG: Placebo|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Diclofenac Potassium 25 mg Tablet Taken Three Times Daily in Subjects With Acute Joint Pain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: diclofenac potassium 25 mg tablet|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant INBRX-106 (Hexavalent OX40 Agonist) in Combination With Pembrolizumab as a Chemotherapy-sparing Regimen for Stage II TNBC (Triple Negative Breast Cancer) Patients
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: INBRX-106
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases
Status: RECRUITING
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: 186RNL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygen Measurements in Subcutaneous Tumors by EPR Oximetry Using OxyChip
Status: TERMINATED
Conditions: Neoplasms, Benign|Neoplasms, Malignant
Interventions: DEVICE: OxyChip
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of Coenzyme Q10 in Hemodialysis Patients
Status: COMPLETED
Conditions: Cardiovascular Disease|End Stage Renal Disease|Atherosclerosis|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AMG 706 and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma
Status: UNKNOWN
Conditions: Lung Cancer|Lymphoma|Lymphoproliferative Disorder|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: motesanib diphosphate|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immidate Effect of Instrument Assited Soft Tissue Mobilization Technique on Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Instrument Assisted Soft Tissue Mobilization|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Double Blind Controlled Trial of an Extensively Hydrolyzed Formula With a Probiotic vs. an Extensively Hydrolyzed Formula Without a Probiotic
Status: COMPLETED
Conditions: Allergy
Interventions: OTHER: Extensively Hydrolyzed Formula with a Probiotic|OTHER: Extensively Hydrolyzed Formula without a Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: SVT-15652 Otic Solution for the Treatment of Otomycosis.
Status: COMPLETED
Conditions: Otomycosis
Interventions: DRUG: SVT-15652|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Virtual BETTER Study
Status: RECRUITING
Conditions: Delivery Modality of BETTER Intervention
Interventions: OTHER: In-Person Prevention Practitioner Visit|OTHER: Video-Call Prevention Practitioner Visit|OTHER: Phone Prevention Practitioner Visit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Sequential Topoisomerase, Irinotecan/Oxaliplatin - Etoposide /Carboplatin in Extensive Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Intervention A: Irinotecan; Oxaliplatin; Neulasta|DRUG: Intervention B: Etoposide; Carboplatin; Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflibercept Injection for Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Vitreous Hemorrhage
Interventions: DRUG: Intravitreal Aflibercept Injection|OTHER: Standard Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nigella Sativa in the Treatment of Palmer Arsenical Keratosis
Status: COMPLETED
Conditions: Arsenical Keratosis
Interventions: DIETARY_SUPPLEMENT: Vitamin E|DIETARY_SUPPLEMENT: Nigella sativa|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Non-small Lung Cancer (NSCLC) With Dual Immune Checkpoint Inhibition
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Stage IV
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Effects of Low Dose Spinal Anesthesia for Cesarean Section
Status: TERMINATED
Conditions: Complications; Cesarean Section|Effects of; Anesthesia, Spinal and Epidural, in Pregnancy|Hemodynamic Instability|Personal Satisfaction
Interventions: DRUG: Bupivacaine 4.5|DRUG: Bupivacaine 9|DRUG: Morphine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: To Characterize the Performance of the Nasal Dilator Strip in Lowering Nasal Resistance During Sleep, Promoting Nasal Route Breathing and Reducing the Signs and Symptoms of Sleep Disordered Breathing in a Group of Chronic Nocturnal Nasal Congestion Sufferers Who Report Trouble With Their Sleep.
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Congestion, Nasal
Interventions: DEVICE: Prototype nasal dilator strip|OTHER: No strip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Disease
Interventions: DRUG: BAY3283142|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pumps for Kids, Infants, and Neonates
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Heart Failure
Interventions: DEVICE: Surgical placement of the Jarvik 2015 VAD|PROCEDURE: Surgical Placement of Jarvik 2015 VAD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Tomotherapy in Locally Advanced Gallbladder and Pancreatic Cancers
Status: COMPLETED
Conditions: Pancreatic Neoplasms Malignant|Malignant Neoplasm of Gall Bladder Non-resectable
Interventions: RADIATION: Tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients
Status: COMPLETED
Conditions: Renal Insufficiency|Kidney Diseases|Urologic Diseases
Interventions: DRUG: Udenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Randomized Controlled Study Aims to Investigate the Effect of Botox Injection in Abdominal Wall Muscle Post Major Abdominal Surgery in Terms of Postoperative Pain, Incidence of Incisional Hernia.
Status: UNKNOWN
Conditions: Hernia, Abdominal
Interventions: BIOLOGICAL: Botox|PROCEDURE: surgery without botox injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel
Status: RECRUITING
Conditions: Peri-implant Mucositis|Mucositis Oral
Interventions: PROCEDURE: Application NaOCl gel + HA gel|PROCEDURE: Non-surgical mechanical debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multi-Center Trial of Anti-Thymocyte Globulin in Treatment of Aplastic Anemia and Other Hematologic Disorders
Status: COMPLETED
Conditions: Anemia, Aplastic|Hematologic Diseases|Pancytopenia|Blood Disease
Interventions: DRUG: antilymphocyte serum|DRUG: nandrolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ZR2 Sequential Immunochemotherapy for Newly Treated MCL
Status: RECRUITING
Conditions: Rituximab, Lenalidomide, Zebutinib ，Mantle Cell Lymphoma
Interventions: DRUG: ZR2 RDHAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DRUG: DMMET-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Interim 18F-FLT PET/CT for Outcome Prediction in Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: 3'-deoxy-3'-[F-18] fluorothymidine: [F-18]FLT|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 Study in Healthy Participants and Participants With Kidney Dysfunction
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: HS-10398|DRUG: HS-10398 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Measurement Using Infrared Camera and Respiratory Volume Monitor (ExSpiron 1Xi) for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia
Status: COMPLETED
Conditions: Prostate Cancer|Bladder Cancer
Interventions: DEVICE: Infrared camera|DEVICE: RVM(Respiratory Volume Monitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement
Status: TERMINATED
Conditions: Aortic Valve Disease|Aortic Stenosis
Interventions: DEVICE: Perceval valve|DEVICE: other stented biological valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: mRNA-4359|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Roll of IV Fluids in the Treatment of Renal Colic
Status: WITHDRAWN
Conditions: Renal Colic
Interventions: DRUG: 0.9% Sodium-chloride|DRUG: Placebos|DRUG: Optalgin, Voltaren, Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sedation Depth in Neurocritical Care
Status: UNKNOWN
Conditions: Sedation of Cerebrovascular Ventilated Critical Care Patients
Interventions: OTHER: Intensive Care Sedation (depth, level)|DRUG: Vasopressors to maintain normal blood pressure values, if needed|DRUG: Osmotherapeutics to lowr intracranial pressure, if needed|PROCEDURE: Endovascular stroke care to treat brain vessel occlusions, if needed|PROCEDURE: Decompressive neurosurgery, if needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Microbial Diversity Between Inflamed and Non-inflamed Skin of Patients With Immune Checkpoint Inhibitor-Induced Dermatitis
Status: COMPLETED
Conditions: Genito-Urinary Neoplasm
Interventions: PROCEDURE: Biospecimen Collection(Punch Biopsy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Novel Neurobehavioral Intervention for Emotion Regulation in Anxiety and Depression Across the Lifespan
Status: COMPLETED
Conditions: Depression, Anxiety|Cognitive Training|Emotion Training|Emotion Regulation
Interventions: BEHAVIORAL: Computerized neurobehavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Chemotherapy With or Without Plasma Exchange in Patients With Newly Diagnosed Multiple Myeloma and Acute Kidney Failure
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm|Renal Failure
Interventions: DRUG: chemotherapy|DRUG: dexamethasone|PROCEDURE: plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Drug 601 in Patients With Wet Age-related Macular Degeneration (wAMD)
Status: UNKNOWN
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: Drug 601|DRUG: Drug 601|DRUG: Drug 601|DRUG: Drug 601|DRUG: Drug 601|DRUG: Drug 601
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Adverse Outcome in Asymptomatic Patients With Prior Coronary Revascularization Who Have a Systematic Stress Testing Strategy Or a Non-testing Strategy During Long-term Follow-up.
Status: RECRUITING
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Coronary Artery Bypass Grafting
Interventions: OTHER: No stress testing|PROCEDURE: stress testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fascia Iliaca Block for Postoperative Pain Control After Elective Hip Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Hip Osteoarthritis
Interventions: DRUG: Naropin, 0.2% Injectable Solution in Sodium chloride|DRUG: Naropin, 0.2% Injectable Solution in dextrose 5%|DRUG: Dextrose 10 % in Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy Induced Neuroplasticity in Post Stroke Patients Suffering Chronic Neurological Deficiencies
Status: COMPLETED
Conditions: Chronic Neurological Deficiency|Stroke
Interventions: PROCEDURE: Hyperbaric Oxygen Therapy (HBOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn About Relapse Prevention of Hypericumextract (a Drug Based on the Plant St. John Wort) in Outpatients Suffering From Moderate Depressive Episodes
Status: COMPLETED
Conditions: Moderate Depressive Episodes (Major Depression)
Interventions: DRUG: Laif® 900, BAY98-7108|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep-Disordered Breathing and PAP in Perinatal Depression
Status: COMPLETED
Conditions: Sleep-disordered Breathing|Major Depressive Disorder
Interventions: DEVICE: Positive Airway Pressure (PAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nor-epinephrine Versus Midodrine/Octreotide in Patients With Hepatorenal Syndrome
Status: COMPLETED
Conditions: Hepato-Renal Syndrome
Interventions: DRUG: Midodrine/Octreotide|DRUG: Nor-epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mechanical,Physiological and Therapeutic Effects of Eccentric Exercise Combined With Extracorporeal Shockwave Therapy in Athletes With Patellar Tendinopathy
Status: COMPLETED
Conditions: Patellar Tendinopathy
Interventions: BEHAVIORAL: Eccentric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Single and Multiple Oral Doses of GLPG3970
Status: COMPLETED
Conditions: Healthy|Psoriasis
Interventions: DRUG: GLPG3970 oral solution|DRUG: Placebo oral solution|DRUG: GLPG3970 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Simvastatin With Guided Bone Regeneration in Ridge Splitting and Simultaneously Implantation
Status: COMPLETED
Conditions: Ridge Splitting|Simvastatin|Immediate Implant
Interventions: PROCEDURE: Immediate implant placement and ARS with GBR and SMV|PROCEDURE: Immediate implant placement and ARS with GBR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daily Wear Corneal Infiltrative Event Study
Status: COMPLETED
Conditions: Myopia|Hyperopia|Corneal Infiltrative Events
Interventions: DEVICE: lotrafilcon A contact lenses|DEVICE: Renu Multiplus|DEVICE: Clear Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK0476 (Montelukast Sodium) and Effects on Asthma and Nasal Symptoms Upon Exposure to Cats (0476-256)
Status: COMPLETED
Conditions: Asthma, Bronchial|Rhinitis, Allergic, Perennial
Interventions: DRUG: MK0476, montelukast sodium|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of BPI-452080 in Subjects With Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor|Renal Cell Carcinoma|Von Hippel-Lindau Disease
Interventions: DRUG: BPI-452080
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases
Status: COMPLETED
Conditions: Central Nervous System Metastases|HER2-positive Breast Cancer|Male Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Tumors Metastatic to Brain
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contributing Factors to Local Bioimpedance Spectroscopy
Status: COMPLETED
Conditions: Fluid and Electrolyte Imbalance|Overhydration|Edema
Interventions: DEVICE: Wearable bioimpedance sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supportive Programs for Supporting Optimal Recovery in Participants Undergoing Gynecological Surgery
Status: COMPLETED
Conditions: Ovarian Neoplasm|Uterine Neoplasm
Interventions: OTHER: Informational Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration|Age-related Maculopathies|Age-related Maculopathy|Maculopathies,Age-related|Maculopathy,Age-related|Retinal Degeneration|Retinal Neovascularization|Eye Diseases
Interventions: BIOLOGICAL: rAAV.sFlt-1|BIOLOGICAL: rAAV.sFlt-1|OTHER: Control (ranibizumab alone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With Cordycepin Plus Pentostatin in Treating Patients With Refractory Acute Lymphocytic or Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Cordycepin|DRUG: Deoxycoformycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo Controlled Phase II Study to Examine the Effects of DAS181 in Healthy Adult Subjects With Laboratory Confirmed Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: DAS181 dry powder, formulation F02|DRUG: Respitose ML006 (DMV-Fonterra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary Hypertension
Status: COMPLETED
Conditions: COPD|Pulmonary Hypertension
Interventions: DRUG: Sildenafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Weight Loss and Psychological Well-being in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: cognitive-behavioral life style intervention|BEHAVIORAL: wellbeing intervention|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 1,5 Anhydroglucitol and 1,5 Anhydroglucitol / Glycated Hemoglobin Ratio as a Potential Biomarker for Islet β-cell Function and Insulin Resistance Among Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: 1,5 Anhydroglucitol and 1,5 Anhydroglucitol / Glycated Hemoglobin ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Letrozole or Tamoxifen in Treating Postmenopausal Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|DRUG: tamoxifen citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia
Status: COMPLETED
Conditions: Episodic Hypoxemia in Mechanically Ventilated Preterm Infants
Interventions: DEVICE: Sequence A: Conventional-Volume Guarantee|DEVICE: Sequence B: Volume Guarantee-Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-delivered Screening & Brief Intervention for Marijuana Use in Pregnancy
Status: COMPLETED
Conditions: Marijuana Use|Pregnancy
Interventions: BEHAVIORAL: eSBIRT|BEHAVIORAL: Tailored texting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Absorption, Metabolism and Excretion of [14C]XZP-3621 in Human
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]XZP-3621
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tranexamic Acid on Joint Inflammation and Cartilage Health in Anterior Cruciate Ligament Injured Patients
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DRUG: Tranexamic Acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Inadvertent Hypothermia in Patients Undergoing Major Spinal Surgery
Status: COMPLETED
Conditions: Hypothermia Following Anesthesia|Neurosurgery|Scoliosis|Kyphosis|Forced Air Warming|Major Spinal Fusion
Interventions: PROCEDURE: Bairhugger Full Access Underbody Blanket|PROCEDURE: Cotton blanket - control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of Dorzol Eye Drops, 20 mg/ml Versus Trusopt® Eye Drops, 20 mg/ml
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma of Both Eyes
Interventions: DRUG: Dorzol 20 mg/ml|DRUG: Trusopt 20 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability and Efficacy of BTX 1204 in Patients With Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: BTX 1204|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polycystic Ovary Syndrome (PCOS) - Effect Of Physical Exercise And Electroacupuncture
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Physical exercise|PROCEDURE: Untreated control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: ADX10059 Migraine Prevention Study
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: ADX10059|DRUG: ADX10059|DRUG: ADX10059|DRUG: ADX10059 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TMC114-TiDP29-C232 - Study Providing Continued Access to Treatment With Darunavir (DRV)/Ritonavir (Rtv) for Children Coming From Any of the Three Ongoing Tibotec Sponsored Pediatric Studies With DRV
Status: COMPLETED
Conditions: HIV-1 Infections
Interventions: DRUG: Darunavir|DRUG: Ritonavir|DRUG: Ritonavir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Darunavir|DRUG: Darunavir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Darunavir|DRUG: Darunavir|DRUG: Ritonavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Double-Blind Randomized Split-Face Study to Evaluate Revanesse® Ultra vs Restylane® for Correction of NLF
Status: COMPLETED
Conditions: Nasolabial Fold Correction
Interventions: DEVICE: Revanesse Ultra|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional Recurrence
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: RADIATION: Photon Therapy|RADIATION: Proton Therapy|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teleassisted Surgery for Gynecological Disease in Obese Patients - OB-ALFX
Status: UNKNOWN
Conditions: Benign, Premalignant and Malignant Gynecological Disease Confined to the Pelvis
Interventions: DEVICE: Telelap ALF-X
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inositol in Preventing Lung Cancer in Current or Former Smokers With Bronchial Dysplasia
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Squamous Lung Dysplasia
Interventions: OTHER: placebo|DRUG: inositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study on the Effect of Electroacupuncture at Both Zusanli and at Both Yanglingquan Acupoints on Cardiovascular Activity
Status: COMPLETED
Conditions: Reaction of Autonomic Nervous System|Reaction of Acupuncture|Reaction of Blood Circulation
Interventions: DEVICE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Baked Milk Tolerance to Treat Eosinophilic Esophagtis
Status: ENROLLING_BY_INVITATION
Conditions: Eosinophilic Esophagitis
Interventions: DIETARY_SUPPLEMENT: Baked Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin, Fluorouracil, Iressa, and Radiation Therapy Patients With Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: Iressa|RADIATION: hyperfractionated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Bobath Treatment Clinical Effects Focused on Stroke Patients
Status: COMPLETED
Conditions: Ischemic Stroke|Spasticity
Interventions: OTHER: Dry needling in a myofascial trigger points area plus physical therapy based on Bobath concept|OTHER: Dry needling in a non myofascial trigger points area plus physical therapy based on Bobath concept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HYZAAR vs. Ramipril for Diabetes (0954A-245)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: DRUG: MK0954A, losartan potassium (+) hydrochlorothiazide (HYZAAR) / Duration of Treatment : 8 Weeks|DRUG: Comparator : ramipril /Duration of Treatment : 8 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effect of Positioning Cushions and Harmonic Techniques on Paratonia in Persons With Dementia
Status: COMPLETED
Conditions: Dementia|Paratonia
Interventions: OTHER: Supporting cushions|OTHER: Harmonic techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha tACS in Dementia With Lewy Bodies
Status: COMPLETED
Conditions: Dementia With Lewy Bodies|Lewy Body Disease
Interventions: DEVICE: Alpha tACS (12 Hz) over the occipital cortex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis
Status: RECRUITING
Conditions: Menstrual Bleeding, Heavy
Interventions: PROCEDURE: Sample Collection and Endometrial Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Learn How Safe BAY2666605 is, How it Affects the Body, How it Moves Into, Through and Out of the Body, the Maximum Amount That Can be Given and Its Action Against Tumors in Adult Participants With Skin Cancer That Has Spread to Other Parts of the Body and Other Types of Advanced Cancer
Status: TERMINATED
Conditions: Metastatic Melanoma and Other Solid Tumors
Interventions: DRUG: BAY2666605
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of LMWH on ICSI in Patients With Unexplained Infertility and Negative Immunological Markers
Status: COMPLETED
Conditions: Unexplained Infertility
Interventions: DRUG: LMWH|OTHER: 0.9% saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Seasonal Malaria Chemoprevention With or Without Lipid-based Nutrient Supplement in Children Aged 6-59 Months in Mali
Status: COMPLETED
Conditions: Malaria
Interventions: DIETARY_SUPPLEMENT: Lipid-based Nutrient Supplement (LNS)|DRUG: Seasonal malaria chemoprevention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on the Early Warning and Treatment of Cervical Spondylosis of Cervical Type on Young People Based on the " Move Generate Yang " Theory
Status: UNKNOWN
Conditions: Cervical Spondylosis of Cervical Type
Interventions: OTHER: Massage of chiropractic and adjusting cervical curvature|OTHER: Sishi Daoyin|OTHER: conventional massage|OTHER: Cervical traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection With OnabotulinumtoxinA (Botox) for the Treatment of Chronic Pelvic Pain
Status: COMPLETED
Conditions: Myofascial Pain Syndromes|Myofascial Trigger Point Pain|Trigger Point Pain, Myofascial
Interventions: DRUG: OnabotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Therapeutic Efficacy of Promitil in Combination With Folfox in Patients With GI Malignancies
Status: TERMINATED
Conditions: Cancer|Gastro-Intestinal Intraepithelial Neoplasia
Interventions: DRUG: Promitil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Levomilnacipran ER (F2695 SR) in Adults With Fatigue Associated With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Levomilnacipran ER|DRUG: Paroxetine, Sertraline, Citalopram or Fluoxetine.|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of IS-001 Injection in Patients Undergoing Robotic Hysterectomy
Status: COMPLETED
Conditions: Ureter Injury
Interventions: DRUG: IS-001|DRUG: No treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Xylitol Chewable Tablets Versus Xylitol Chewing Gum in Geriatric Bedridden Patients
Status: UNKNOWN
Conditions: Saliva Altered|Plaque
Interventions: DRUG: Listerine ready tabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Sana Treatment in Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Sana Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NSAID Phase II for Non-central Involved Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: nepafenac 0.1% drops|OTHER: Nepafenac Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroinflammatory PET Imaging in Autoimmune Encephalomyelitis
Status: RECRUITING
Conditions: Autoimmune Encephalomyelitis
Interventions: DIAGNOSTIC_TEST: 18F-DPA-714 PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Epidural Anesthesia and Analgesia on Quality of Recovery After Radical Prostatectomy.
Status: COMPLETED
Conditions: Anesthesia|Anesthesia Recovery Period|Radical Prostatectomy|Patient Satisfaction|Postoperative Period|Quality of Life|Analgesia|Epidural|Quality of Recovery
Interventions: PROCEDURE: Epidural anesthesia with light general anesthesia|DRUG: Postoperative epidural analgesia|PROCEDURE: General anesthesia|DRUG: Continuous intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Clinical Benefits of EnvarsusXR in Post Liver Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Liver Transplant
Interventions: DRUG: EnvarsusXR|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION