pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness and Safety of CCoat Intra-Articular Injections in Mild to Moderate Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: CCoat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Treatment by Glofitamab in Combination With Rituximab or Obinutuzumab Plus CHOP in Patients With RIchter Syndrome
Status: RECRUITING
Conditions: Richter Syndrome
Interventions: DRUG: Glofitamab + Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Interventions and Butyrate Production in Behçet's Patients
Status: COMPLETED
Conditions: Behcet Syndrome
Interventions: DIETARY_SUPPLEMENT: Oral butyrate|DIETARY_SUPPLEMENT: Vegetarian diet|DIETARY_SUPPLEMENT: Habitual diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prilosec Over-the-counter (OTC)® Versus Prevacid® for Gastric Acid Suppression
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Prilosec OTC (omeprazole-magnesium)|DRUG: Prevacid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rivastigmine in Mild Alzheimer's Disease, FMRI Study
Status: COMPLETED
Conditions: Alzheimer' Disease
Interventions: DRUG: rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma (DLBCL)
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: Lymphodepleting chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Saccharomyces Boulardii and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants
Status: UNKNOWN
Conditions: Anticandidal Property of Saccharomyces Boulardii on Very Low Birth Weight Infants
Interventions: DIETARY_SUPPLEMENT: Reflor|DRUG: mikostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Precision Dosing of Vancomycin in Critically Ill Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Vancomycin
Interventions: DEVICE: vancomycin model-informed precision dosing|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Resiliency Program for Fathers of Children and Youth With Special Health Care Needs
Status: COMPLETED
Conditions: Stress|Family|Fathers
Interventions: BEHAVIORAL: Relaxation Response Resiliency Program for Father of CYSHCN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: HyGIeaCare Prep vs Split-dose PEG Prep Prior to Colonoscopy
Status: WITHDRAWN
Conditions: Colonoscopy
Interventions: DEVICE: HyGIeaCare Prep|PROCEDURE: Colonoscopy|DRUG: polyethylene glycol (PEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
Status: RECRUITING
Conditions: Cervical Cancers
Interventions: DIETARY_SUPPLEMENT: enteral immunonutrition|DIETARY_SUPPLEMENT: standard oral enteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Trial of Bavituximab Combined With Ribavirin for Initial Treatment of Chronic HepC Virus Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Bavituximab|DRUG: Pegylated interferon (PEG-IFN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of EG-301 in Patients With Nonfocal Geographic Atrophy Secondary to dAMD
Status: NOT_YET_RECRUITING
Conditions: Non-Exudative (Dry) Age-related Macular Degeneration (dAMD)
Interventions: DRUG: EG-301|DIETARY_SUPPLEMENT: AREDS2 supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients
Status: COMPLETED
Conditions: BK Virus Infection
Interventions: DRUG: Everolimus|DRUG: Mycophenolic acid dose reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment for Moderate to Severe Acne
Status: COMPLETED
Conditions: Acne
Interventions: DRUG: Minocycline, Clindamycin, Tretinoin, Benzoyl Peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Motor Imagery Intervention on Functional Recovery Following Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Knee Arthroplasty
Interventions: OTHER: Motor imagery practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Persistent Postsurgical Pain After Breast Surgery With a Pectoral Nerves Block (Pecs) Type II
Status: COMPLETED
Conditions: Chronic Post-Procedural Pain|Breast Cancer
Interventions: OTHER: Chronic pain evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiation Therapy and Hormone Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: flutamide|DRUG: goserelin acetate|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Short-term Oxygen During CPET in ILD
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease
Interventions: PROCEDURE: Incremental exercise test (IET)|PROCEDURE: Constant work rate exercise test (CWRET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study of EUS-RFA for Inoperable Pancreatic Ductal Adenocarcinoma
Status: SUSPENDED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DEVICE: EUS-RFA using Habib Tm as a probe|PROCEDURE: EUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Misoprostol For Nulliparous Women Before Hysteroscopy
Status: UNKNOWN
Conditions: Cervical Ripening
Interventions: DRUG: misoprostol|DRUG: oral misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Compressive Anastomosis for Biliojejunostomy and Pancreaticojejunostomy During Whipple's Procedure
Status: UNKNOWN
Conditions: Cholangiocarcinoma|Pancreatic Neoplasms|Duodenal Neoplasms|Pancreatolithiasis|Chronic Pancreatitis
Interventions: PROCEDURE: Magnetic Compressive Anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implications of Tamarkoz® on Stress, Emotion, Spirituality and Heart Rate
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Tamarkoz®|BEHAVIORAL: Stress management resources
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Leningrado 5 Association in the Treatment of Hypertension
Status: WITHDRAWN
Conditions: Arterial Hypertension
Interventions: DRUG: LENINGRADO 5 association|DRUG: Natrilix® SR|OTHER: Natrilix SR Placebo|OTHER: Leningrado 5 association Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intervention and Mechanism of ICBT on Chronic Itching in Patients With Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BEHAVIORAL: Internet Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Study the Effects of CD25 and Low Dose Cyclosporin in the Treatment of Active Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Daclizumab|DRUG: Cyclosporine|DRUG: cyclosporine and Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-Over Study of Sevelamer Hydrochloride and Sevelamer Carbonate
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: sevelamer carbonate, sevelamer hydrochloride|DRUG: sevelamer hydrochloride, sevelamer carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Study of IO-108 as Single Agent and in Combination With a PD-1 Immune Check Point Inhibitor in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: IO-108|BIOLOGICAL: IO-108 + pembrolizumab combination therapy|BIOLOGICAL: IO-108 + cemiplimab combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin and Clopidogrel HIgh DOse in Stable Patients With Residual High Platelet Activity
Status: COMPLETED
Conditions: Stable Angina
Interventions: DRUG: atorvastatin and clopidogrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of AL-704; Single Dose, Food Effect in Healthy Volunteers; Multiple Doses in Chronic Hepatitis C
Status: TERMINATED
Conditions: Chronic Hepatitits C
Interventions: DRUG: AL-704|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aclarubicin for the Treatment of Retinal Vasculopathy With Cerebral Leukodystrophy
Status: COMPLETED
Conditions: Vasculopathy, Retinal, With Cerebral Leukodystrophy|Cerebroretinal Vasculopathy, Hereditary
Interventions: DRUG: aclarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARIpiprazole in Anorexia NErvosa
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: DRUG: aripiprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Electrophysiologic Effects of BMS-394136 on the Atrium and Ventricle in Patients With Dual-Chamber Pacemakers or Defibrillators
Status: COMPLETED
Conditions: Heart Diseases
Interventions: DRUG: BMS-394136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Study Comparing Single and Multiport Laparoscopic Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: SILS TEP repair|PROCEDURE: Total extraperitoneal inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
Status: COMPLETED
Conditions: Metabolic Complications
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cytomegalovirus Hyperimmune Globulin (CMV-Ig) Replacement in Hypogammaglobulinemic Lung Transplant Recipients
Status: COMPLETED
Conditions: Hypogammaglobulinemia
Interventions: DRUG: CMV-Ig
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8|Unresectable Breast Carcinoma|Metastatic Melanoma|Unresectable Melanoma|Cutaneous Squamous Cell Carcinoma|Merkel Cell Carcinoma|Soft Tissue Sarcoma|Bone Sarcoma|Sarcoma,Soft Tissue|Sarcoma of Bone
Interventions: BIOLOGICAL: Anti-CD40 Agonist Monoclonal Antibody CDX-1140|DRUG: Poly ICLC|RADIATION: Radiation Therapy|BIOLOGICAL: Recombinant Flt3 Ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers
Status: WITHDRAWN
Conditions: Vision; Disorder, Loss|Caregiver Burnout|Quality of Life|Depression|Anxiety|Sleep
Interventions: BEHAVIORAL: Sahaj Samadhi Meditation|BEHAVIORAL: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Healthy Dads Healthy Kids Latino
Status: COMPLETED
Conditions: Feasibility
Interventions: BEHAVIORAL: The Papás Saludables, Niños Saludables Program|BEHAVIORAL: The Papás Saludables, Niños Saludables Wait-list Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intraocular Pressure (IOP) Lowering Efficacy of Transdermal Brimonidine Therapy
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Brimonidine|DRUG: Placebo Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nocturnal Non-invasive Ventilation in Patients With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: non-invasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)
Status: COMPLETED
Conditions: Atrial Fibrillation Chronic|Persistent Atrial Fibrillation
Interventions: PROCEDURE: Cryo or RF Ablation only of Pulmonary Veins|PROCEDURE: Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Posterior-anterior Spinal Mobilization and Prone Press up in Patients With Non Specific Low Back Pain
Status: COMPLETED
Conditions: Non-specific Low Back Pain
Interventions: OTHER: Traditional Physical Therapy|OTHER: Posterior-anterior spinal mobilization, prone press up Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cardiac Rehabilitation Programme in Hypertensive Rheumatoid Arthritis Patients
Status: RECRUITING
Conditions: Cardiac Rehabilitation|Rheumatoid Arthritis|Hypertension
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Long-Term Safety and Efficacy of ABX464 in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ABX464
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor|PIK3CA Mutation|PTEN Loss of Function Mutation
Interventions: DRUG: Serabelisib|OTHER: Insulin Suppressing Diet|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Pain Control in Liver Surgery Patients
Status: COMPLETED
Conditions: Pain, Postoperative|Hepatocellular Carcinoma
Interventions: DRUG: Pregabalin|DRUG: Placebo (for Pregabalin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: sunitinib malate dose escalation|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Keep Exercising & Stay Steady: Development and Feasibility of a Digital Health Intervention to Encourage Exercise Maintenance After Fall Prevention Exercise Programmes End.
Status: NOT_YET_RECRUITING
Conditions: Fall Patients
Interventions: BEHAVIORAL: Keep Exercising and Stay Steady
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bio-Integrative, Fiber-Reinforced Kneebar for Treating Subchondral Insufficiency of the Knee
Status: NOT_YET_RECRUITING
Conditions: Subchondral Insufficiency Fracture
Interventions: DEVICE: Ossiofiber® Trimmable Fixation Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Mechanism of Action of Ligelizumab (QGE031) in Patients With Chronic Urticaria
Status: TERMINATED
Conditions: Chronic Spontaneous Urticaria|Cholinergic Urticaria|Cold Urticaria
Interventions: DRUG: Ligelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation
Status: COMPLETED
Conditions: Peritonitis Infectious|Candida Infection
Interventions: OTHER: To evaluate the initial levels and kinetics of serum β-D-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy of Mini Sling Versus Transobturator Tape in Surgical Management of Women With Stress Urinary Incontinence
Status: NOT_YET_RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: transobturator tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SEQUAR SEmitendinosus vs QUadriceps in Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear
Interventions: PROCEDURE: ACL Reconstruction with Semitendinosus graft|PROCEDURE: ACL Reconstruction with Quadriceps tendon-bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer
Status: COMPLETED
Conditions: Cancer|Prostate Neoplasms
Interventions: DRUG: Leuprolide or goserelin|DRUG: Transdermal estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEISH-F3 + GLA-SE and the LEISH-F3 + MPL-SE Vaccine
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: BIOLOGICAL: GLA-SE|BIOLOGICAL: LEISH-F3|BIOLOGICAL: MPL-SE|DRUG: SE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Immune Responses to Inactivated Influenza Vaccine: a Pilot Study
Status: COMPLETED
Conditions: Influenza Virus Vaccine
Interventions: BIOLOGICAL: Trivalent Inactivated Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Status: RECRUITING
Conditions: Neurofibromatosis 1
Interventions: DRUG: N-Acetyl cysteine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intradialytic Exercise on the Fatigue, Sleep Disorder, Arterial Stiffness and Endothelial Function in Uremic Patients
Status: COMPLETED
Conditions: Hemolysis|Exercise|Sleep Disorder|Fatigue|Adipocytes
Interventions: OTHER: Cycling exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bevel Position of the Artery Needle on Puncture Pain and Post-puncture Bleeding Time
Status: COMPLETED
Conditions: Pain|Bleeding Time|Arteriovenous Fistula
Interventions: OTHER: Bevel Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Train of Four, Tetanus 50 and 100 Hz Recovery After Rocuronium Block Reversed by Neostigmine
Status: COMPLETED
Conditions: Postoperative Residual Curarization
Interventions: DEVICE: TOF scan train of four ratio monitoring|DEVICE: ITF device tetanus stimulation monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: cCeLL - Ex Vivo (Confocal Fluorescence Endomicroscopy) for Intraoperative Brain Tumor Diagnosis
Status: NOT_YET_RECRUITING
Conditions: Benign Brain Tumor|Malignant Brain Tumor
Interventions: DIAGNOSTIC_TEST: cCeLL - Ex vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-label Clinical Trial to Compare the Safety and Effectiveness of Adaptive Versus Conventional Deep Brain Stimulation
Status: WITHDRAWN
Conditions: Parkinson Disease
Interventions: DEVICE: adaptive DBS delivered through AlphaDBS IPG System|DEVICE: conventional DBS delivered through AlphaDBS IPG System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abemaciclib and Pembrolizumab in Locally Advanced Unresectable or Metastatic Gastroesophageal Adenocarcinoma: Big Ten Cancer Research Consortium BTCRC-GI18-149
Status: TERMINATED
Conditions: Gastroesophageal Cancer|Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Music Therapist's and Stroke Patient's Engagement Levels and Patient's Fingers and Wrist Movement
Status: TERMINATED
Conditions: Hemiparesis;Poststroke/CVA
Interventions: OTHER: Music Therapeutic Interaction and Verbal Interaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study to Assess the Efficacy and Safety of Denosumab Produced by Two Different Processes in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Denosumab (CP2)|DRUG: Denosumab (CP4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Mirror Therapy on Post-Needling Pain Following Deep Dry Needling of Myofascial Trigger Point in Lateral Elbow Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Lateral Elbow Pain
Interventions: PROCEDURE: Experimental: Deep Dry Needling (DDN), Ischemic Compression, Cold Spray with Stretching + MFT|PROCEDURE: Deep Dry Needling (DDN), Ischemic Compression, Cold Spray with Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Icotinib Hydrochloride in Treating Patients With Advanced Cancers
Status: WITHDRAWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: icotinib hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Detection of Circulating Tumor Cells (CTCs) in Patients With Renal Cancer Undergoing Cryosurgery Combined With DC-CIK Treatment
Status: COMPLETED
Conditions: Neoplastic Cells, Circulating
Interventions: OTHER: Flow cytometry (FCM)|OTHER: RT-PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Umbralisib Plus Ublituximab in Participants With Treatment Naïve Follicular Lymphoma
Status: TERMINATED
Conditions: Follicular Lymphoma|Small Lymphocytic Lymphoma
Interventions: DRUG: Ublituximab|DRUG: Umbralisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Single Dose Paracetamol on the Lower Airways of Asthmatic and Healthy Children
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transobturator Urethral Sling Placement With an Autologous Rectus Facia
Status: COMPLETED
Conditions: Stress Urinary Incontinence|Surgery--Complications
Interventions: PROCEDURE: Mid-urethral sling placement using autologous rectus fascia|PROCEDURE: Mid-urethral sling placement using synthetic mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Efficacy and Safety of Gabapentin in the Treatment of Patients With Painful Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: DRUG: gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Deep Brain Stimulation of the Amygdala for Treatment-Refractory Combat Post-Traumatic Stress Disorder
Status: WITHDRAWN
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Week 0 Medtronic 3387 electrodes/Activa PC amygdala DBS|DEVICE: Week 12 Medtronic 3387 electrodes/Activa PC amygdala DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ARISTA-AH for Restoring Hemostasis Following Posterior Long-segment Spinal Fusion.
Status: RECRUITING
Conditions: Hemostatics|Hemostasis|Spinal Deformity|Spinal Fusion
Interventions: DEVICE: Control Group|DEVICE: ARISTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treadmill Training Effects on Cardiorespiratory Endurance and Constipation in Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cardiopulmonary
Interventions: OTHER: Traditional physical herapy|OTHER: Treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Approval Clinical Study of the Talent Thoracic Stent Graft to Treat Thoracic Aortic Aneurysms (THRIVE)
Status: TERMINATED
Conditions: Thoracic Aortic Aneurysms
Interventions: DEVICE: Talent Thoracic Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canadian Health Economics, Outcome, and Effectiveness Comparison of Treatment in Patients With Chronic Rhinosinusitis
Status: TERMINATED
Conditions: Chronic Rhinosinusitis
Interventions: DEVICE: Relieva Balloon Sinuplasty™ System|PROCEDURE: Functional Endoscopic Sinus Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial to Learn if a COVID-19 Therapeutic is Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: REGN14284|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperhidrosis, Developing a Treatment Approach Aims 1 & 2
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Aluminum Chloride 20% (deodorant)|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment
Status: COMPLETED
Conditions: Brain Tumor|Central Nervous System Tumors|Cachexia|Leukemia|Lymphoma|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: cyproheptadine hydrochloride|DRUG: megestrol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: Olaparib|DIETARY_SUPPLEMENT: Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AO-176 in Multiple Solid Tumor Malignancies
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: AO-176|DRUG: AO-176 + Paclitaxel|DRUG: AO-176 + Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilates Method on Functional Capacity and Blood Pressure of Elderly Women With Type 2 Diabetes
Status: COMPLETED
Conditions: Type-2 Diabetes|Physical Disability|Blood Pressure
Interventions: OTHER: PILATES Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure in Migraine: Single-blinded, Randomized, Controlled Clinical Trial
Status: COMPLETED
Conditions: Migraine; Status
Interventions: DEVICE: Acupressure elastic band (Sea-Band)|DEVICE: General elastic band (no bud)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study To Examine The Safety, Tolerability And Pharmacokinetics Of PF-02545920 In Psychiatrically Stable Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PF-02545920|DRUG: PF-02545920|DRUG: PF-02545920|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Consequences of Eccentric Cycling on Exercise-related Neuromuscular Responses and Biomarkers in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Session (a)|OTHER: Session (b)|OTHER: Session (c)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: pembrolizumab|DRUG: lenvatinib|DRUG: regorafenib|DRUG: TAS-102 (trifluridine and tipiracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training With Leva System for Urge Incontinence
Status: TERMINATED
Conditions: Overactive Bladder|Urge Urinary Incontinence|Mixed Urinary Incontinence
Interventions: DEVICE: Leva device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Self-Management and Health Coaching for Type 2 Diabetes - Impact on Diabetes Clinical and Wellness Indicators
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Dario Blood Glucose Monitoring System|BEHAVIORAL: CDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
Status: COMPLETED
Conditions: Urethral Stricture|Surgery|Urologic Diseases
Interventions: PROCEDURE: Transecting anastomotic repair (tAR)|PROCEDURE: Vessel-sparing anastomotic repair (vsAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Neratinib Pill|DRUG: Fam-Trastuzumab Deruxtecan-Nxki (TDxD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durability Extension Study to Assess Clinical Activity and Safety of Enobosarm (GTx-024) in Stress Urinary Incontinence
Status: WITHDRAWN
Conditions: Stress Urinary Incontinence
Interventions: DRUG: GTx-024|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline in Treatment of Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: pentoxifylline (Trental SR®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerance of Epigenetic and Immunomodulating Drugs Combined With Chemotherapeutics in Patients Suffering From Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreas Cancer|Pancreatic Adenocarcinoma|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Romidepsin|DRUG: Azacitidine|DRUG: nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Durvalumab|DRUG: Lenalidomide capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
Status: COMPLETED
Conditions: Substance Abuse|Substance Dependence|Alcohol Abuse|Drug Use|Relapse
Interventions: BEHAVIORAL: Dual Processing|BEHAVIORAL: Relapse Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Phase II Study of Adjuvant Pembrolizumab Versus Placebo in Head and Neck Cancers at High Risk for Recurrence- the PATHWay Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deferoxamine and Xingnaojing Injection Treatment in Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: deferoxamine|DRUG: Xingnaojing injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Socket Casting Methods: Improving Form and Fit
Status: COMPLETED
Conditions: Lower Limb Amputation
Interventions: DEVICE: Symphonie Aqua SystemTM|PROCEDURE: Hand Casting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PECBLOCK for the Treatment of Pain After Breast Surgery
Status: COMPLETED
Conditions: Cancer|Pain
Interventions: PROCEDURE: PECBLOCK under echoguidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Development and Implementation of a Remote ECG-monitored Prospective Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts
Status: COMPLETED
Conditions: Covid19|Hydroxychloroquine|Coronavirus Infection|Transmission|Prophylaxis
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hospital Registry of Acute Myocarditis: Evolution of the Proportion of Positive SARS-COV-2 (COVID19) Cases
Status: COMPLETED
Conditions: Acute Myocarditis
Interventions: DIAGNOSTIC_TEST: Performing routine care (clinical and paraclinical tests)|DIAGNOSTIC_TEST: Examinations for the research:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vaccine Therapy in Treating Patients With Stage II, Stage IIIA, Stage IIIB, or Stage IVA Liver Cancer
Status: WITHDRAWN
Conditions: Liver Cancer
Interventions: BIOLOGICAL: alpha fetoprotein adenoviral vector vaccine|BIOLOGICAL: alpha fetoprotein plasmid DNA vaccine|BIOLOGICAL: sargramostim plasmid DNA hepatocellular carcinoma vaccine adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: To Assess the Effects of Single Dose of JMKX001899 on QTc Interval in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: JMKX001899|DRUG: JMKX001899|DRUG: JMKX001899|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Effects of Ganshuang Combined TDF to Treat CHB and NAFLD
Status: COMPLETED
Conditions: Chronic Hepatitis B|Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Chronic Hepatitis B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Skeletally Anchored Reversed PowerScope Appliance in Orthodontic Treatment of Patients With Class III Malocclusion
Status: UNKNOWN
Conditions: Effect of PowerScope Appliance in Treatment of Patients With Class 3 Malocclusion
Interventions: DEVICE: powerscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cognition and MRI Markers in MS Patients With Aubagio® Treatment
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Clinical assessment|OTHER: Ecological evaluation|OTHER: Neuropsychological evaluation|OTHER: Psychological evaluation|DEVICE: MRI Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
Status: RECRUITING
Conditions: Diffuse Cutaneous Systemic Sclerosis
Interventions: DRUG: Placebo|DRUG: Ianalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foot and Ankle Range of Motion (Stretching) Apparatus
Status: TERMINATED
Conditions: Plantar Fasciitis|Flatfoot|Calcaneus Fractures
Interventions: DEVICE: Non-Measuring Ankle Exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Response Modifier in the Treatment of Breast, Ovarian, Endometrial and Cervical Cancers
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Endometrial Cancer|Cervical Cancer
Interventions: DRUG: 852A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Neurobehavioural Mechanism of Cannabidiol (CBD) for Alcohol Dependence
Status: UNKNOWN
Conditions: Alcohol Use Disorder (AUD)
Interventions: DRUG: Cannabidiol (CBD)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ACTIVE SCHOOL - Effects on Academic Performance of Novel Approaches to Increase Physical Activity in School-children
Status: RECRUITING
Conditions: Academic Performance
Interventions: BEHAVIORAL: 'Run, Jump & Fun' intervention|BEHAVIORAL: 'Move & Learn' intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Janagliflozin Treat T2DM Monotherapy
Status: UNKNOWN
Conditions: Diabetes Type 2
Interventions: DRUG: Janagliflozin 25mg|DRUG: Janagliflozin 50mg|DRUG: Placebo/Janagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correction of Asymptomatic 2nd Degree Cystocele in Patient With Stress Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: trans-obturator tape inside-out usingsoft tapes.|PROCEDURE: anterior colporraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Vaccine Booster Study in Healthy Children 12-18 Mths Old Previously Primed With the Same Vaccines
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Synflorix|BIOLOGICAL: Tritanrix-HepB|BIOLOGICAL: Hiberix|BIOLOGICAL: Polio Sabin|BIOLOGICAL: Poliorix|BIOLOGICAL: Prevenar (Wyeth)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028)
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Omarigliptin|DRUG: Placebo to omarigliptin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Furmonertinib in Advanced NSCLC Patients With EGFR Uncommon Mutation
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|EGFR G719X|EGFR L861Q|EGFR S768I
Interventions: DRUG: Furmonertinib 160 mg, Q.D.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate MW33 Injection
Status: COMPLETED
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: MW33 injection|COMBINATION_PRODUCT: MW33 injection placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts
Status: COMPLETED
Conditions: Heroin Dependence
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT