pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Expression of Protein Tyrosine Phosphatase 1B (PTP1B) and Body Composition Modification in Patients With Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: PROCEDURE: Blood sampling|PROCEDURE: Bioelectrical impedance vector analysis|PROCEDURE: Muscular echography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnetic Resonance Imaging (MRI) for Aortic Dissection to Visualise Inflammation
Status: UNKNOWN
Conditions: Aortic Dissection|Aortic Diseases
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI) using ultrasmall super paramagnetic iron oxides (USPIOs)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ibrutinib as Early Therapy in Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Malignant Neoplasms Stated as Primary Lymphoid Haematopoietic|Chronic Lymphocytic Leukemia|Small Lymphocytic Leukemia
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Subthreshold Exercise Program for Concussion--R01
Status: RECRUITING
Conditions: Concussion, Brain|Concussion, Mild|Brain Injuries, Traumatic|Persistent Post Traumatic Headache|Post-Concussion Syndrome|Post-Concussive Syndrome, Chronic
Interventions: BEHAVIORAL: MSTEP|BEHAVIORAL: Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine and Inflammation in Hemodialysis Patients
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: DRUG: Colchicine 0.5 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C)
Status: UNKNOWN
Conditions: Colorectal Neoplasms|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms
Interventions: DRUG: Apatinib Mesylate Tablets|DRUG: Bevacizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Four Months Moxifloxacin Containing Daily Regimen Study Among New Pulmonary Tuberculosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: Isoniazid|DRUG: Rifampicin|DRUG: Pyrazinamide|DRUG: Ethambutol|DRUG: Moxifloxacin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery
Status: COMPLETED
Conditions: Fissure;Anal|Fistula;Rectal|Hemorrhoids
Interventions: DRUG: anesthesics plus antiinflammatory, CLIFE1|DRUG: local anesthesics, CLIFE2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
Status: UNKNOWN
Conditions: Urinary Retention|Uterine Prolapse
Interventions: PROCEDURE: Spinal anesthesia|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Anesthesia in PROstate Biopsy Pain Obstruction Study
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: perineal nerve block|BEHAVIORAL: periprostatic block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Irrigant Types Used During Endodontic Treatment on Postoperative Pain
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: OTHER: Irrigant type|DRUG: 5.25% NaOCl|DRUG: 5.25% Cloraxid gel/ distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of First-line Treatment of Small Cell Lung Cancer (SCLC) With Anlotinib Hydrochloride
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Versus Duloxetine for the Prevention of Taxane-Induced Peripheral Neuropathy In Breast Cancer Patients
Status: COMPLETED
Conditions: Peripheral Neuropathy|Chemotherapy-induced Peripheral Neuropathy|Breast Cancer
Interventions: DRUG: Lidocaine in Saline|DRUG: Duloxetine 30 MG|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Beta-3 Agonist and Anti-muscarinic Agent for Sjogren's Syndrome With Overactive Bladder
Status: UNKNOWN
Conditions: Sjogren's Syndrome|Overactive Bladder Syndrome
Interventions: DRUG: mirabegron|DRUG: oxybutynin, tolterodine, solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Long-term Conditions With Survival Following Heart Attack in England and Wales
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Diabetes Mellitus|Peripheral Vascular Disease|Chronic Heart Failure|Cerebrovascular Disease|Chronic Renal Failure|Chronic Obstructive Pulmonary Disease
Interventions: OTHER: long term conditions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiplaque Effect of Essential Oils and 0.2% Chlorhexidine on an in Situ Model of Oral Biofilm Growth.
Status: COMPLETED
Conditions: Oral Biofilm|Mouthwash|Periodontitis
Interventions: DRUG: Essential oils|DRUG: 0.2% chlorhexidine|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples
Status: RECRUITING
Conditions: Infertility, Male
Interventions: OTHER: Round Spermatid Injection (ROSI)|OTHER: Half ROSI-half Sperm Donor Fertilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Obturator Nerve Blockade and Neuromuscular Blockade
Status: COMPLETED
Conditions: Cancer of Bladder
Interventions: DRUG: Obturator block|DRUG: Neuromuscular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ranibizumab (Lucentis) for Macular Edema Secondary to Vein Occlusions
Status: COMPLETED
Conditions: Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Intravitreal injection of ranibizumab .3 dose|DRUG: Intravitreal injection of Ranibizumab .5 dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Frequency and Quality of Sleep Apnea Care Management
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Self-Management Care|BEHAVIORAL: Self-Management Mobile Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: New Measures for Tracheobronchial Anatomy
Status: COMPLETED
Conditions: Thoracic CT-scan|Right Upper Lobe Anatomy|Right Sided Double Lumen Endobronchial Tube
Interventions: PROCEDURE: Measurement of the length of the right main stem bronchus|PROCEDURE: Measurement of the right upper lobe bronchus antero-posterior angulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determine the Clinical Advantage of IV vs PO Acetaminophen
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Acetaminophen IV Soln|DRUG: Oral Acetaminophen|DRUG: Placebo Pills|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metronomic Therapy in Patients With Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: vinblastine|DRUG: Cyclophosphamide|DRUG: dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uptitration Trial of Flibanserin Versus Placebo in Premenopausal Women With Hypoactive Sexual Desire Disorder
Status: COMPLETED
Conditions: Sexual Dysfunctions, Psychological
Interventions: DRUG: flibanserin|DRUG: flibanserin 50mg|DRUG: flibanserin 100mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Efficacy and Tolerability of Oral DFD-29 Capsules for the Treatment of Rosacea (MVOR-2)
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: DFD-29|DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Metabolism After Laparoscopic Gastric Bypass Surgery (BABS)
Status: COMPLETED
Conditions: Evaluation of Expected Bone Loss After Bariatric Surgery|Possible Prevention of Bone Loss After Surgery by Calcium and Vitamin D Supplementation
Interventions: DRUG: Calciferol, calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Psychosis Treatment in the Long Term, Unitary Group Study (APLUS)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xylitol Adult Caries Trial (X-ACT)
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: xylitol|DIETARY_SUPPLEMENT: inactive lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Different Electrophysical Agents in Hamstring Muscles Flexibility of Healthy Individuals
Status: UNKNOWN
Conditions: Flexibility|Hamstring Muscles
Interventions: PROCEDURE: Hotpack Group|PROCEDURE: Infrared Group|PROCEDURE: Ultrasound Group|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Absorption of Paracetamol in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study Evaluating the Efficacy of an Intervention Aimed at Reducing the Length of Stay After Transfemoral Transcatheter Aortic Valve Implantation
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Cardiovascular Diseases
Interventions: OTHER: Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant
Status: RECRUITING
Conditions: Post-Lung Transplantation Bronchiectasis
Interventions: DEVICE: POWERBreathe Plus®|OTHER: Cardiopulmonary rehabilitation post lung transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Trial of Adjuvanted and Non-adjuvanted Trivalent Influenza Vaccine in Tropical Africa
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Adjuvanted seasonal trivalent inactivated influenza vaccine|BIOLOGICAL: Seasonal trivalent inactivated influenza vaccine|BIOLOGICAL: Saline (bacteriostatic 0.9% sodium chloride for injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: OligoG DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Left Ventricular Systolic Dysfunction|Mitral Valve Prolapse
Interventions: PROCEDURE: mitral valve repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
Status: WITHDRAWN
Conditions: Atherosclerosis
Interventions: DRUG: Ezetrol (Ezetimibe)|DRUG: Vytorin (Ezetimibe + Simvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlating the Measure of Retinal Vascular Density Through Angio-OCT With Calcium Score
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Abnormalities|Vascular Diseases|Retinal Vascular
Interventions: OTHER: Ophthalmologic consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: filgrastim|DRUG: prednisone|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Postoperative Total Wavefront Pattern Between Two Types of Intraocular Lenses Implanted in Cataract Surgery
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: phacoemulsification with intraocular lens implantation|DEVICE: ocular aberrometer assesment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa
Status: COMPLETED
Conditions: CIN 2/3|HIV Infections
Interventions: DRUG: Intravaginal 5-Fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Azvudine|DRUG: Nirmatrelvir-Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High and Intermediate Risk Degenerative Mitral Regurgitation Treatment: A Trial Comparing MitraClip® to Surgical Therapy
Status: TERMINATED
Conditions: Mitral Valve Insufficiency
Interventions: DEVICE: MitraClip®|PROCEDURE: Mitral valve Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54175446 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-54175446|DRUG: Minocycline|DRUG: JNJ 54175446 Matching Placebo|DRUG: D Amphetamine|DRUG: D Amphetamine Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Study the Efficacy and Safety of BEJO Red Ginger in COVID-19 Patients With Mild Symptoms
Status: UNKNOWN
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: BEJO Red Ginger Extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Dosing Study With a New Insulin Glargine Formulation and Lantus® in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine HOE901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Art Intervention on Decreasing Pain and Anxiety During Intravenous Cannulation
Status: COMPLETED
Conditions: Catheterization|Pain|Anxiety|Art|Children
Interventions: OTHER: Trace Image and Coloring for Kids-Book (TICK-B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nutritional Intervention With the Dietary Supplement, Immunocal® in MCI Patients: Promotion of Brain Health
Status: UNKNOWN
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DIETARY_SUPPLEMENT: Immunocal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Simple Mechanical Device to Control Pressure in the Balloon of the Endotracheal Tube to Prevent Ventilator-acquired Pneumonia
Status: RECRUITING
Conditions: Mechanical Ventilation|Tracheal Intubation|Ventilator-acquired Pneumonia|Intubation -Related Tracheal Lesions
Interventions: DEVICE: Nosten® pressure control (it's not an antibiotic, but simple device)|OTHER: Manual pressure control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture as Pain Relief and Relaxation During Childbirth
Status: COMPLETED
Conditions: Acupuncture Analgesia|Natural Childbirth
Interventions: PROCEDURE: Acupuncture|OTHER: TENS|OTHER: Traditional Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hyaluronic Acid and Corticosteroid Intra-articular Injections for the Treatment of Osteoarthritis of the Hip
Status: UNKNOWN
Conditions: Coxarthrosis
Interventions: DRUG: Corticosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Testing of Dose-escalation of SAR440234 in Patients With Acute Myeloid Leukemia, Acute Lymphoid Leukemia and Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Leukaemia
Interventions: DRUG: SAR440234
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrates and Gut Hormones After Gastric Bypass Surgery
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: Glucose + Fructose|OTHER: Sucrose|OTHER: Isomaltulose|OTHER: Sucrose + Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analysis of Deposition With Nebulizers Membrane
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DEVICE: phase 1 - jet nebulizer|DEVICE: Phase 2- mesh nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Elpida®|DRUG: Rifampin|DRUG: Rifabutin|DRUG: Clarithromycin|DRUG: Omeprazole|DRUG: Atorvastatin|DRUG: Levonorgestrel+Ethinylestradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Malignant Mesothelioma|Colorectal Cancer|Bile Duct Cancer|Rectal Cancer|Ovary Cancer|Pancreatic Cancer|Breast Cancer Female
Interventions: BIOLOGICAL: UCMYM802 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAW2020 on OSA Endotypic Traits
Status: ENROLLING_BY_INVITATION
Conditions: Obstructive Sleep Apnea (OSA)
Interventions: DRUG: Placebo oral capsule|DRUG: DAW2020 oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Types of Carbohydrates Consumed After Exercise on Blood Fat Levels
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BEHAVIORAL: Exercise|OTHER: Diet (meal type)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Temperature Plasma Ablation Combined Lacrimal Duct Catheterization in the Treatment of Lacrimal Duct Obstructive
Status: UNKNOWN
Conditions: Lacrimal Duct Obstruction
Interventions: PROCEDURE: Low temperature plasma lacrimal duct obstruction ablation combined with lacrimal duct catheterization|PROCEDURE: YAG lacrimal duct laser combined with lacrimal duct catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: drug eluting-stent|DEVICE: drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Anastrozole and Palbociclib in Metastatic HER2-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Female Breast Carcinoma|Breast Cancer
Interventions: DRUG: anastrozole|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes
Status: COMPLETED
Conditions: Cataract|Lens Opacities|Presbyopia
Interventions: DEVICE: IOL implantation experimental|DEVICE: IOL implantation active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: speed dependent treadmill training on moderate speed|DEVICE: speed dependent treadmill training on slow speed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of IMP4297 Capsule (JS109) Combined With Irinotecan in the Treatment of Advanced Malignant Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: COMBINATION_PRODUCT: JS109 combine with irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis
Status: COMPLETED
Conditions: Hyperphosphatemia|Kidney Failure
Interventions: DRUG: ferric citrate, ca acetate, sevelamer carbonate, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate 13 Valent Pneumococcal Conjugate Vaccine (13vPnC) Vaccine Followed by 23-valent Pneumococcal Polysaccharide Vaccine (23vPS) Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Status: COMPLETED
Conditions: Vaccines, Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13vPnC|BIOLOGICAL: 23vPS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Post-Marketing Clinical Study to Assess Efficacy and Safety of Dexmedetomidine in Post-Operative Patients
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Treatment With EGb 761(r) on Blood Markers of Inflammation and Oxidative Stress in Patients With MCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DRUG: TEBOFORTAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crenolanib Maintenance Following Allogeneic Stem Cell Transplantation in FLT3-positive Acute Myeloid Leukemia Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Crenolanib besylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Headache Inducing Effect of Cromakalim in Migraine Patients
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: DRUG: Levcromakalim|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Trial to Assess the Antipsychotic Efficacy of ITI-007 Over 6 Weeks of Treatment
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ITI-007|DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALC-919 For The Treatment Of Common Warts
Status: COMPLETED
Conditions: Verruca Vulgaris
Interventions: DRUG: 2014-ALC-919-US|DRUG: Vehicle-Control Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pulmonary SUlcus, Pancoast and Chest Wall Non-small Cell Lung Cancer Employing Radiation, Immuno-oncology and Resection
Status: RECRUITING
Conditions: Lung Cancer Patients|Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Durvalumab|RADIATION: Non-ablative oligofractionated radiation (NORT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neuro+ Attention Training
Status: COMPLETED
Conditions: ADHD
Interventions: BEHAVIORAL: Neuro+ Attention Training|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: lomustine|DRUG: procarbazine hydrochloride|DRUG: temozolomide|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction and Subjective Effects of Compounds for Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid Abuse|Opioid Dependence|Opioid-Related Disorders|Opioid Use
Interventions: DRUG: Lorcaserin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis
Status: COMPLETED
Conditions: ANCA-associated Vasculitis
Interventions: DRUG: CCX168 10 mg, twice daily, plus cyclophosphamide/rituximab plus glucocorticoids|DRUG: CCX168 30 mg, twice daily, cyclophosphamide/rituximab plus glucocorticoids|OTHER: Placebo, twice daily, plus cyclophosphamide/rituximab plus glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Viral or Bacterial Infections|Pneumonia|Pneumonia, Viral|Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: AV-001 Injection|DRUG: AV-001 Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Calcineurin Inhibitor Sparing After Kidney Transplantation
Status: COMPLETED
Conditions: CNI Side Effects
Interventions: DRUG: Cyclosporine & Cellcept|DRUG: Prograf & Cellcept|DRUG: Low Dose CNI (Cyclosporine or FK) and Cellcept|DRUG: Rapamune and Cellcept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ProspEctive First Evaluation in Chest Pain Trial
Status: COMPLETED
Conditions: Chest Pain|Shortness of Breath|Suspected Acute Coronary Syndrome
Interventions: PROCEDURE: Coronary CT Angiography|PROCEDURE: Stress Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotherapy Combined With Chemoradiotherapy for First-line Treatment of Esophageal Squamous Cell Carcinoma（ChinECR）
Status: ACTIVE_NOT_RECRUITING
Conditions: ESCC
Interventions: DRUG: Immunotherapy|DRUG: Chemotherapy drug|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-39393406 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-39393406|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate in Combination With Intermittent Erlotinib in Patients With Previously Treated, Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: eribulin mesylate + erlotinib|DRUG: eribulin mesylate + erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carpal Tunnel Release Via Two Small Incisions Comparing With Via Standard Incision And Under Endoscope
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Carpal Tunnel Release via limited approaches|PROCEDURE: Carpal Tunnel Release via standard approach|PROCEDURE: Endoscopic Carpal Tunnel Release|DEVICE: endoscope or an arthroscopic device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia After Minithoracotomy
Status: COMPLETED
Conditions: Postoperative Pain|Mitral Valve Disease
Interventions: PROCEDURE: Erector Spinae Plane blockade|DRUG: Oxycodone|PROCEDURE: general anesthesia|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VEGF Trap in Treating Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: ziv-aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Proton Radiation Therapy for Low and Intermediate Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: 70 Gy/CGE|RADIATION: 72.5 Gy/CGE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toxicity Substudy of Evaluation of Subcutaneous Proleukin in a Randomised International Trial (ESPRIT): TOXIL-2 Substudy
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: ondansetron, ibuprofen, paracetamol|DRUG: Ondansetron, ibuprofen, paracetamol|DRUG: metoclopramide, ibuprofen, paracetamol|DRUG: Metoclopramide, codeine phosphate, ibuprofen, paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pair 2 Care: Peer Support for Caregivers of Black Americans Living With Dementia
Status: ENROLLING_BY_INVITATION
Conditions: Family Caregiver|Dementia|Peer Support
Interventions: BEHAVIORAL: Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Status: TERMINATED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Opebacan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of the Hydroxyethyl Starch on Kidney Injury in Pediatric Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Crystalloid|DRUG: Colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Low Dose Naltrexone in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Persian Gulf Syndrome
Interventions: DRUG: Low Dose Naltrexone|DRUG: Placebo - sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dutasteride in Treating Patients With Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: dutasteride|DRUG: gadolinium-chelate|OTHER: active surveillance|PROCEDURE: diffusion-weighted magnetic resonance imaging|PROCEDURE: functional magnetic resonance imaging|PROCEDURE: prostate biopsy|PROCEDURE: ultrasound imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: DRUG: anlotinib combined with dose-dense temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NE ED90 Bolus in C-Sec
Status: NOT_YET_RECRUITING
Conditions: Hypotension|Hypertension|Nausea|Pain|Arrhythmia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Evaluation of Budesonide/Formoterol SPIROMAX® Inhalation Powder Versus SYMBICORT® TURBOHALER®
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol SPIROMAX®|DRUG: SYMBICORT® TURBOHALER®|DRUG: SYMBICORT placebo|DRUG: SPIROMAX Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enoxaparin and/or Minocycline in Acute Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Enoxaparin|DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Safety and Efficacy of Belatacept With That of Cyclosporine in Patients With a Transplanted Kidney
Status: COMPLETED
Conditions: Graft Rejection|Kidney Transplantation|Renal Transplantation
Interventions: DRUG: Belatacept|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil (MMF)|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Long-Term Efficacy and Safety Study of Ixekizumab (LY2439821) in Participants With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EUS - Guided Choledocho-duodenostomy Versus ERCP With Covered Metallic Stents in Patients With Unresectable Malignant Distal Common Bile Duct Strictures
Status: COMPLETED
Conditions: Malignant Biliary Obstruction
Interventions: PROCEDURE: EUS-guided choledocho-duodenostomy|PROCEDURE: Endoscopic retrograde cholangiopancreatography with covered metallic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity, Safety of GSKs Tdap Vaccine Boostrix When Coadministered With GSKs Influenza Vaccine Fluarix in Adults
Status: COMPLETED
Conditions: Acellular Pertussis|Diphtheria|Tetanus
Interventions: BIOLOGICAL: Fluarix®|BIOLOGICAL: Boostrix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Selection Using Next Generation Sequencing vs Urine Culture
Status: COMPLETED
Conditions: Kidney Stone|Renal Stone|Infection, Bacterial
Interventions: OTHER: NGS + Antibiotic Recommendation|PROCEDURE: Standard of Care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Feasibility Study of Somatostatin Receptors PET Imaging for the Diagnosis of Infective Endocarditis
Status: UNKNOWN
Conditions: Infective Endocarditis
Interventions: DRUG: 68Ga-DOTATOC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of 2 Doses of Intravenous Droperidol in the Prevention of Postoperative Nausea
Status: TERMINATED
Conditions: Nausea|Vomiting
Interventions: DRUG: Droperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the PK, PD, Safety and Tolerability of Eplontersen in Healthy Chinese Volunteers
Status: RECRUITING
Conditions: Transthyretin-mediated Amyloidosis
Interventions: DRUG: Eplontersen Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ePRO for Adjuvant Therapy of Colorectal Adenocarcinoma
Status: RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Electronic Patients Reported Outcomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Spinal Needles in Ultrasound-guided Fine Needle Aspirations From Thyroid Nodules
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: DEVICE: Spinal needle (25G)|DEVICE: Conventional fine needle (25G)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequential Intranodal Immunotherapy (SIIT) Combined With Anti-PD1 (Pembrolizumab) in Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: RADIATION: Radiotherapy|BIOLOGICAL: Rituximab|BIOLOGICAL: Autologous dendritic cells|BIOLOGICAL: GM-CSF|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Techniques of Subthreshold Diode Laser Cyclophotocoagulation in Refractory Glaucoma
Status: UNKNOWN
Conditions: Refractory Glaucoma
Interventions: DEVICE: 360 degrees subthreshold diode laser cyclophotocoagulation|DEVICE: 180 degrees subthreshold diode laser cyclophotocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Mapping Using Ultra-high Frequency Electrocardiography
Status: COMPLETED
Conditions: Left Bundle-Branch Block|Right Bundle-Branch Block|Non-Specific Intraventricular Conduction Defect
Interventions: DIAGNOSTIC_TEST: Ultra-high frequency electrocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Curodont™ Repair in Patients With Early Approximal Carious Lesions
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Curodont Repair|DEVICE: Fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Heavy and/or Prolonged Menstrual Bleeding Without Organic Cause
Status: COMPLETED
Conditions: Improve Quality of Life|Heavy Menstrual Bleeding
Interventions: DRUG: combined contraceptive pills (microcept)|DRUG: medroxyprogesterone acetate (progest)|DRUG: mefenamic acid (ponstan forte)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Doxorubicin in Treating Patients With Metastatic or Locally Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: doxorubicin hydrochloride|DRUG: vorinostat|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Safety of Flu Cell Culture Derived Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Vaccine
Status: COMPLETED
Conditions: Novel Influenza A (H1N1)|A New Flu Virus of Swine Origin
Interventions: OTHER: Non-intervention observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ciclophosphamide, Vincristine, Myocet and Prednisone, With Rituximab in 1st-Line Treatment for Patients With No-Hodgkin B Lymphoma and Cardiovascular (CV) Risk
Status: UNKNOWN
Conditions: No Hodgkin B Lymphoma
Interventions: DRUG: RCOMP-14 + rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does a Daily Iron Tablet Improve Anemia in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Anemia, Iron-Deficiency
Interventions: DRUG: Ferrous sulfate 325mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MEDI-547 to Evaluate the Safety, Tolerability, and Biologic Activity of IV Administration in Subjects With Relapsed or Refractory Solid Tumors
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: MEDI-547
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Asthma Disparities Through School-Based Telemedicine for Rural Children
Status: COMPLETED
Conditions: Asthma|Quality of Life|Children
Interventions: OTHER: Asthma Education Sessions|OTHER: Asthma Health Assessment via Telemonitoring|OTHER: Provider Treatment Prompt|OTHER: School Absenteeism|OTHER: Prescription Filling Profile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phosphodiesterase (PDE) Inhibitors Effect on Cognitive Deficits Associated to Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Cognitive Deficits
Interventions: DRUG: Papaverine or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH