pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)
Status: COMPLETED
Conditions: Cocaine-related Disorder
Interventions: DRUG: AFQ056|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Open-Label, Multicenter, Controlled, Pivotal Study to Assess Safety and Efficacy of ELAD in Subjects w/ AILD
Status: TERMINATED
Conditions: Acute Alcoholic Hepatitis
Interventions: BIOLOGICAL: ELAD System|OTHER: Standard of Care (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices.
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Malnutrition|Aged|Prognosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound-guided Paravertebral Block Versus Mid-point Transverse Process Pleura Block in Mastectomy Surgery
Status: COMPLETED
Conditions: Mastectomy; Lymphedema|Anesthesia, Local|Surgery
Interventions: DRUG: bupivacaine|DEVICE: 22 gauge 100 mm needle|DRUG: Propofol|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XIENCE V: SPIRIT WOMEN Sub-study
Status: COMPLETED
Conditions: Coronary Artery Stenosis|Coronary Arteriosclerosis|Coronary Artery Disease|Coronary Artery Restenosis|Total Coronary Occlusion|Stent Thrombosis|Vascular Disease|Myocardial Ischemia
Interventions: DEVICE: XIENCE V®/ XIENCE PRIME™|DEVICE: CYPHER SELECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of AZD1722 in Constipation Predominant Irritable Bowel Syndrome (IBS-C)
Status: COMPLETED
Conditions: Constipation Predominant Irritable Bowel Syndrome
Interventions: DRUG: AZD1722|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ReAHEAD: A Study to Find Out Whether Education Improves Adherence to Dabigatran in People With Atrial Fibrillation Who Are Younger Than 75 Years
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dabigatran
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single-port LC Might be Preferable for Managing Ovarian Dermoid Cyst.
Status: COMPLETED
Conditions: Abdominal Pain|Ovarian Spillage|Endobag Rupture|Ovarian Reserve
Interventions: PROCEDURE: Ovarian cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Pulmonary Rehabilitation in Children With Primary Immunodeficiency
Status: RECRUITING
Conditions: Primary Immunodeficiency
Interventions: OTHER: Inspiratory muscle training|OTHER: Upper extremity aerobic exercise training|OTHER: Lower extremity aerobic exercise training|OTHER: Resistant exercise training|OTHER: Thoracic expansion exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Trimodulin in Subjects With Severe COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Trimodulin|OTHER: Placebo (human albumin 1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of The Efficacy and Safety Of Tri-ActiveTM In Treatment Of Cellulite
Status: TERMINATED
Conditions: Cellulite|Body Contouring
Interventions: DEVICE: TRI-ACTIVE LASERDERMOLOGYTM (DEKA M.E.L.A., Itália)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Tizanidine HCl Tablets 4 mg of Dr.Reddys Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tizanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: COMBINATION_PRODUCT: vancomycin hydrochloride and tobramycin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Favipiravir Compared to Placebo in Subjects With Mild COVID-19
Status: COMPLETED
Conditions: Sars-CoV2|COVID-19
Interventions: DRUG: Favipiravir|DRUG: Placebo|OTHER: Standard of care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaginal Infection Study 2
Status: COMPLETED
Conditions: Vaginal Infection
Interventions: DRUG: clindamycin phosphate/butoconazole nitrate|DRUG: butoconazole nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative or Operative Treatment of Fractures in the Neck of the 5th Metacarpal Bone
Status: COMPLETED
Conditions: Fractures of the Neck
Interventions: PROCEDURE: Bouquet pinning of the 5th metacarpal bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anatomy-Based Fitting in Unexperienced Cochlear Implant Users
Status: RECRUITING
Conditions: Cochlear Implants|Sensorineural Hearing Loss
Interventions: DEVICE: Default CI fitting|DEVICE: Anatomy-based CI fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DEVICE: Virtual Reality Neurocognitive Exercises administered through an Oculus Headset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Effect of Safinamide on Levodopa Pharmacokinetics
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Safinamide + Levodopa|OTHER: Placebo + Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Palbociclib in Combination With Fulvestrant Versus Fulvestrant in Advanced Breast Cancer: A Real-world Study in China
Status: UNKNOWN
Conditions: Breast Cancer|Fulvestrant|Palbociclib
Interventions: DRUG: Fulvestrant Injectable Product|DRUG: Palbociclib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab, Lenalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma Eligible for Stem Cell Transplant
Status: COMPLETED
Conditions: Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Rituximab in Treating Patients With Stage I-II Grade 1 or Grade 2 Follicular Lymphoma
Status: RECRUITING
Conditions: Ann Arbor Stage I Grade 1 Follicular Lymphoma|Ann Arbor Stage I Grade 2 Follicular Lymphoma|Ann Arbor Stage II Grade 1 Follicular Lymphoma|Ann Arbor Stage II Grade 2 Follicular Lymphoma
Interventions: OTHER: Clinical Observation|RADIATION: Radiation Therapy|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Study of Photodynamic Therapy Combined With Sonodynamic Therapy in Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: Hematoporphyrin Injection actived by photodynamic therapy combined with Sonodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TROPHY PAH Pivotal Study - TReatment of Pulmonary HYpertension for PAH Pivotal Study
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension
Interventions: DEVICE: Pulmonary artery denervation|DEVICE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TruSkin®: Study for Treatment of Chronic Venous Leg Ulcers
Status: TERMINATED
Conditions: Chronic Venous Leg Ulcers
Interventions: OTHER: TruSkin|OTHER: Wound Cover
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison Between Sentinel Lymph Node Biopsy and Lymph Node Dissection in Early Stage Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Sentinel lymph node mapping|PROCEDURE: Routine lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Blood Pressure in Prehypertensive Older Rural Women Also Known as Wellness for Women: DASHing Toward Health
Status: COMPLETED
Conditions: Pre-Hypertension
Interventions: BEHAVIORAL: Tailored Internet Newsletters|BEHAVIORAL: Tailored print newsletters delivered via mail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Early Real-Time Electronic Health Record Risk Algorithm for the Prevention and Treatment of Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Early Nephrology Consult (ENC)|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Rehabilitation in Long COVID-19 Patients With Persistent Breathlessness and Fatigue
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection
Interventions: OTHER: Cardiopulmonary exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Open-label Clinical Study on the Prevention of Premature Ovarian Failure After HSCT
Status: NOT_YET_RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Premature Ovarian Failure
Interventions: DRUG: leuprorelin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Facilitated Release of Endogenous Enterokines
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Mixed-Meal|DIETARY_SUPPLEMENT: Electrolyte Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of an Intervention of Pharmacotherapeutic Plans to Reduce Medication-related Problems in Geriatric Residences
Status: RECRUITING
Conditions: Polypharmacy
Interventions: OTHER: systematic and structured review of patient pharmacotherapeutic treatment plans
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endostar Combined With SBRT and Envafolimab in the Treatment of Advanced Gastrointestinal Tumors
Status: RECRUITING
Conditions: Gastrointestinal Neoplasms
Interventions: DRUG: Envafolimab Injection|DRUG: Endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Low Dose Rifaximin ER|DRUG: Low Dose Rifaximin DER|DRUG: High Dose Rifaximin ER|DRUG: High Dose Rifaximin DER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Tislelizumab in Combination With Lenvatinib in Patients With Selected Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: lenvatinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ultrasonic Noise Exposure on Human Hearing
Status: COMPLETED
Conditions: Hearing Loss
Interventions: OTHER: Ultrasonic noise exposure|DIAGNOSTIC_TEST: Pure Tone Audiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Test the Efficacy and Safety of YM178 in Subjects With Symptoms of Overactive Bladder
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: YM178|DRUG: tolterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intervention in Allergic Patients
Status: COMPLETED
Conditions: Allergic Rhinitis Due to Weed Pollen|Montelukast
Interventions: BEHAVIORAL: Start taking Montelukast Sodium Tablets 10mg quaque die orally two weeks before peak pollen count.|BEHAVIORAL: Montelukast Sodium Tablets 10mg quaque die orally was administered after peak pollen count.|DRUG: No oral drug therapy throughout the pollen period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High Gastrointestinal Bleed Risk Outcomes in Patients With Non-valvular Atrial Fibrillation (NVAF) in France
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Apixaban|DRUG: Rivaroxaban|DRUG: Dabigatran|DRUG: Vitamin K antagonist (VKA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postoperative Analgesia in Breast Cancer Surgery: Safety and Efficiency of Ultrasound Guided Erector Spinae Plane Block
Status: COMPLETED
Conditions: Breast Cancer Surgery|Postoperative Analgesia
Interventions: PROCEDURE: erector spinae plane block|PROCEDURE: sham erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Levetiracetam Treatment of Neonatal Seizures
Status: TERMINATED
Conditions: Neonatal Seizures
Interventions: DRUG: Oral levetiracetam|DRUG: Intravenous phenobarbital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Study Of Azithromycin Switch Therapy For Treatment Of Community Acquired Pneumonia (CAP)
Status: COMPLETED
Conditions: Community Acquired Pneumonia (CAP)
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Laryngeal Mask Versus Endotracheal Tube Undergoing Laparoscopic Cholecystectomy Surgery
Status: NOT_YET_RECRUITING
Conditions: Cholecystitis
Interventions: DEVICE: Video laryngeal mask airway|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pazopanib, Docetaxel, Prednisone Prostate
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Pazopanib|DRUG: Docetaxel|DRUG: Pazopanib|DRUG: Prednisone|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BeFAST or BeSTRONG: Brain Change After Fun Athletic Sports-skill Training or Brain Change After Strength TRaining Focusing ON Gait
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: BeFAST|BEHAVIORAL: BeSTRONG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Safety Study of Arformoterol/Tiotropium Combination Versus Either Therapy Alone in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Bronchitis|Emphysema
Interventions: DRUG: Arformoterol Tartrate Inhalation Solution|DRUG: Tiotropium|DRUG: Arformoterol and Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8|Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8|Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8
Interventions: DRUG: Trifluridine and Tipiracil Hydrochloride|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Temperature Telemonitoring of Patients With COVID-19 and Other Infectious Diseases in Hospital at Home Using Viture
Status: COMPLETED
Conditions: COVID-19|Infectious Disease|Tract Infection, Urinary|Bacteremia|Respiratory Infection|Cellulitis
Interventions: DEVICE: Continuous wearable thermometer placed on patient's armpit to monitor body temperature remotely
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis
Status: RECRUITING
Conditions: Chronic Pancreatitis|Chronic Pain
Interventions: DIAGNOSTIC_TEST: Quantitative Sensory Test 1|DIAGNOSTIC_TEST: Quantitative Sensory Test 2|DIAGNOSTIC_TEST: Quantitative Sensory Test 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Glucose Reduction by Early Acarbose Treatment in Basal Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Acarbose (Glucobay, BAYG5421)|DRUG: Voglibose (Basen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychometric Properties of the SMART Feeding Tool
Status: COMPLETED
Conditions: Feeding; Difficult, Newborn|Premature Infant Disease|Dysphagia of Newborn|Nurse's Role|Feeding Disorder of Infancy or Early Childhood|Trauma and Stressor Related Disorders|Deglutition Disorders in Infants|Malnutrition, Infant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of NeisVac-C Vaccine to Evaluate Immunological Interference With Hepatitis B, Inactivated Polio and Acellular Pertussis Vaccines in Healthy Infants
Status: COMPLETED
Conditions: Meningitis, Meningococcal
Interventions: BIOLOGICAL: Group C Meningococcal Polysaccharide-Tetanus Toxoid Conjugate Vaccine (GCMP-TT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors|Soft Tissue Sarcoma|Ewing Sarcoma|Malignant Epithelial Neoplasm|Rhabdomyosarcoma|Wilms Tumor|Hepatic Tumor|Germ Cell Tumor|Bone Metastases
Interventions: DEVICE: Magnetic Resonance-Guided High Intensity Focused Ultrasound|DRUG: Lyso-thermosensitive Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effectiveness of Individual Education Plans for Childhood Cancer Survivors
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Central Nervous System Tumors|Lymphoma
Interventions: BEHAVIORAL: Annual Intervention Group|BEHAVIORAL: Quarterly Monitoring of IEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Soluble Beta-Glucan (SBG) in Treatment of Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Soluble beta-glucan (SBG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients
Status: COMPLETED
Conditions: Sanfilippo Syndrome Type A (MPS IIIA)
Interventions: DRUG: SOBI003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tacrolimus in Korean Nephropathy Patients
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: Tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early-Line Anti-EGFR Therapy to Facilitate Retreatment for Select Patients With mCRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Panitumumab|DRUG: Cetuximab|DRUG: Irinotecan|DRUG: FOLFIRI Protocol|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genicular Artery Embolization vs Nerve Ablation Intervention (GENI) for Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Geniculate artery embolization|PROCEDURE: Genicular nerve phenol nerve ablation|PROCEDURE: Skin infiltration of 2cc of 0.25% bupivacaine at the knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Enhance New CGM Use in Early Childhood (SENCE)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: CGM + Family Behavioral Intervention|DEVICE: Standard CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Isoleucine Added ORS in Children With Diarrhoea
Status: COMPLETED
Conditions: Acute Infectious Diarrhoea in Children
Interventions: OTHER: ORS + Isoleucine|OTHER: ORS without Isoleucine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Glucose Metabolism Disorders|Metabolic Disease
Interventions: DEVICE: Continuous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Mobilization of Operatively Stabilized Distal Radius Fractures - a Randomized Controlled Trail
Status: COMPLETED
Conditions: Closed Fracture of Lower End of Radius and Ulna
Interventions: OTHER: Questionnaire|RADIATION: X- Ray|OTHER: Grip Strength|OTHER: VAS Score|OTHER: Range of Motion measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venus Versa Diamondpolar Applicator Treatment Followed by AC Dual Applicator Treatment for Facial Acne Vulgaris
Status: TERMINATED
Conditions: Acne Vulgaris
Interventions: DEVICE: Venus Versa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effects of GLPG3667 Given as an Oral Treatment for 4 Weeks in Adults With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: GLPG3667|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conservative Treatment of Catheter - Related Injections With Gentamicine/EDTA
Status: COMPLETED
Conditions: Patients With Uncomplicated Long-term Central Venous Catheter-related Biofilm-related Infection
Interventions: DRUG: Gentamicins-EDTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of This Study is to Reveal the Influence of Active Video Games on Children's Motor Coordination
Status: COMPLETED
Conditions: The Study Demonstrated the Effect of Active Video Games on Motor Coordination in Children Over a 12-week Intervention
Interventions: BEHAVIORAL: Active video games|BEHAVIORAL: Traditional sports games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 4 of 7)
Status: COMPLETED
Conditions: Exposure to Man-made Visible Light
Interventions: OTHER: Visible light exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NOV120101 (Poziotinib) for 1st Line Monotherapy in Patients With Lung Adenocarcinoma
Status: TERMINATED
Conditions: Adenocarcinoma of Lung Stage IIIB|Adenocarcinoma of Lung Stage IV
Interventions: DRUG: NOV120101 (Poziotinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Link Between Bladder Sensation and Changes in Skin Electrical Conductance and Heart Rate.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Tolterodine|PROCEDURE: Filling cystometry|PROCEDURE: Intravesical neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of SARS-CoV2 Virus (COVID-19) Seroprevalence Among Lyon-Bron Military Health Schools Personnel
Status: COMPLETED
Conditions: SARS-CoV Infection|Covid19
Interventions: DIAGNOSTIC_TEST: Anti-SARS-CoV2 Serology|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liothyronine in Children With Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure
Status: COMPLETED
Conditions: Tricuspid Atresia|Heart Defects, Congenital
Interventions: DRUG: liothyronine I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Four Stool Processing Methods Combined With Xpert MTB/RIF Ultra for Diagnosis of Intrathoracic Paediatric TB (TB-Speed - Stool Processing)
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DIAGNOSTIC_TEST: Xpert MTB/Rif Ultra on stool samples|DIAGNOSTIC_TEST: Xpert MTB/Rif Ultra on respiratory sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fluvoxamine Maleate in the Treatment of Depression/Depressive State : A Post-marketing Clinical Study in Children and Adolescents
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Fluvoxamine maleate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Vitamin D on Glycemic Control and Proinflammatory Markers in Adolescents With T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes|Vitamin D Deficiency/Insufficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bariatric Surgery and Modulation of Perceived Satiety
Status: RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: Sleeve gastrectomy|PROCEDURE: OverStitch™ Endoscopic Suturing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Rituximab in Treating Patients With Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LutrePulse Hypogonadotropic Hypogonadism
Status: COMPLETED
Conditions: Primary Amenorrhea With Hypogonadotropic Hypogonadism
Interventions: DRUG: Gonadorelin acetate subcutaneous (SC) 10 μg/pulse as a fixed dose, administered via. OmniPod pump|DRUG: Gonadorelin acetate SC 15 μg/pulse as a fixed dose, administered via. OmniPod pump|DRUG: Gonadorelin acetate SC 20 μg/pulse as a fixed dose, administered via. OmniPod pump|DRUG: Placebo (SC 10, 15, or 20 μg/pulse as a fixed dose, administered via. OmniPod pump)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Caregiver Adaptation to Patient Institutionalization
Status: COMPLETED
Conditions: Dementia|Stroke|Heart Disease
Interventions: BEHAVIORAL: Psychoeducational Support|BEHAVIORAL: Information only control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Degludec and Glargine U100 for Management of Hospitalized and Discharged Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Degludec|DRUG: Glargine|DRUG: Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases
Status: COMPLETED
Conditions: Brain Metastases
Interventions: RADIATION: Hippocampal sparing whole brain radiotherapy|RADIATION: Conventional whole brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Registry to Assess Frequency, Risk Factors, Management, and Outcomes of Arterial and Venous Thromboembolic Complications
Status: RECRUITING
Conditions: Covid19|Thrombosis Embolism|DVT|Pulmonary Embolism|Myocardial Infarction|Stroke
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PRECISION-T2D Study: Precision Nutrition Study for Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: White bread|OTHER: Whole wheat bread|BEHAVIORAL: Plant-based diet|OTHER: Conventional diabetic diet|OTHER: Follow-up visit every 1-2 years
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Breathing Exercises for Pulmonary Function of Post-laparotomy Patients .
Status: COMPLETED
Conditions: Laparotomy Patients
Interventions: OTHER: Interdigital exercise|OTHER: Blow-Bottle technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPV as Potential Protection Against COVID-19
Status: UNKNOWN
Conditions: Poliovirus Vaccine, Oral|COVID|Mortality|Morbidity|Non-Specific Effects of Vaccines
Interventions: BIOLOGICAL: oral polio vaccine + information|BEHAVIORAL: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PAR-101/OPT-80 Versus Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhea (CDAD)
Status: COMPLETED
Conditions: Clostridium Infections|Diarrhea
Interventions: DRUG: PAR-101/OPT-80|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Magnetic Stimulation for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Magnetic stimulation|DEVICE: Sham magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Metformin and clemastine in combination|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Control of Liver Metastases From Colorectal Cancer With Cetuximab and Hepatic Artery Infusion of Chemotherapy
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer|Liver Metastases|Hepatic Lesions
Interventions: DRUG: IV cetuximab|DRUG: HAI chronomodulated chemotherapy|DRUG: HAI conventional chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Pharmacokinetics of Omeprazole, Rosiglitazone, and Desipramine When Administered With Avanafil in Healthy Male Subjects
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Omeprazole|DRUG: Rosiglitazone|DRUG: Desipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Planning Service Delivery Integration For HIV Positive And At-Risk Women In Botswana: A Hybrid Type 2 Clinical Intervention And Implementation Strategy
Status: COMPLETED
Conditions: Family Planning
Interventions: OTHER: WHO Decision-Making Tool for Family Planning Clients and Providers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Treatment Study for Memory Impairment and Depression
Status: COMPLETED
Conditions: Depression|Mild Cognitive Impairment
Interventions: DRUG: Donepezil|DRUG: Placebo|DRUG: Citalopram|DRUG: Venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Posaconazole vs. Fluconazole for Prevention of Invasive Fungal Infection (P05387 AM1)(COMPLETED)
Status: COMPLETED
Conditions: Leukopenia
Interventions: DRUG: Posaconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Long-Term Safety and Effectiveness Study to Evaluate Pitolisant in Adult Patients With Idiopathic Hypersomnia
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Hypersomnia|Excessive Daytime Sleepiness
Interventions: DRUG: Pitolisant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Efficacy and Pharmacokinetics of Copanlisib in Pediatric Patients
Status: TERMINATED
Conditions: Relapsed or Refractory Solid Tumors or Lymphoma in Children|Neuroblastoma|Osteosarcoma|Rhabdomyosarcoma|Ewing Sarcoma
Interventions: DRUG: Copanlisib (BAY806946)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Placebo Analgesia. Does Extended Information About Dental Procedures Reduce Pain Induced by Dental Treatment?
Status: COMPLETED
Conditions: Anxiety|Odontophobia
Interventions: OTHER: anesthetics and extended information before dental treatment|OTHER: anesthetics and standard information before dental treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Giving a Low Carbohydrate Diet to Overcome Hypertension
Status: UNKNOWN
Conditions: Hypertension|African Americans|Diet, Carbohydrate-Restricted|Risk Reduction Behavior
Interventions: OTHER: Very low carbohydrate diet|OTHER: Standard DPP-GLB diet|BEHAVIORAL: Standard DPP-GLB program modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy and DLI for Prevention of Second Relapse in Patients With Relapsed Acute Leukemia After Allotransplant
Status: UNKNOWN
Conditions: Donor Lymphocyte Infusion|Allogeneic Hematopoietic Stem Cell Transplantation|Acute Leukemia|Minimal Residual Disease|Graft-versus-host Disease|Relapse
Interventions: DRUG: donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Comparing a Fixed-Dose Capsule of Esomeprazole 40mg and LDA 325mg With Free Combination
Status: COMPLETED
Conditions: Ulcers|Upper GI Symptoms
Interventions: DRUG: Esomeprazole 40mg/ASA 325mg|DRUG: Esomeprazole|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Additional Effect of Tongue Scraping on Halitosis Parameters in Initial Periodontal Therapy
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Halitosis|Tongue Condition
Interventions: OTHER: tongue scraper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine Supplementation and Cognitive and Physical Tests
Status: COMPLETED
Conditions: Healthy|Creatine Supplementation
Interventions: DIETARY_SUPPLEMENT: Creatine|DIETARY_SUPPLEMENT: Calcium lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human Lung Responses to Respiratory Pathogens
Status: COMPLETED
Conditions: Respiratory Infection
Interventions: DIETARY_SUPPLEMENT: Vitamin D3 (cholecalciferol)|DIETARY_SUPPLEMENT: Placebo Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sirolimus in Combination With Metronomic Chemotherapy in Children With Recurrent and/or Refractory Solid and CNS Tumors
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Sirolimus|DRUG: Celecoxib|DRUG: Etoposide|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol vs. Midazolam With Propofol for Sedative Endoscopy in Patients With Previous Paradoxical Reaction to Midazolam
Status: COMPLETED
Conditions: Sedation|Endoscopy
Interventions: DRUG: Propofol|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrospective Analysis of the Outcome of Patients With Relapsed/Refractory Acute Myeloid Leukemia Included in a Patient Named Program of Gemtuzumab Ozogamicin/Mylotarg®
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Gemtuzumab Ozogamicin (GO)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tumor Antigen-sensitized DC Vaccine as an Adjuvant Therapy for Esophagus Cancer
Status: UNKNOWN
Conditions: Carcinoma|Esophagus Cancer
Interventions: BIOLOGICAL: Tumor antigen-sensitized DC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Needle-free Dental Anesthesia
Status: SUSPENDED
Conditions: Anesthesia, Local|Needle Phobia
Interventions: COMBINATION_PRODUCT: Meso-Jet, 2% lidocaine(xylocaine)|COMBINATION_PRODUCT: Needle,2% lidocaine(xylocaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial to Assess 68Ga Bombesin PET/CT (NeoB) Imaging for Staging of Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: [68Ga]GA-NeoB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Erector Spinae Plane Block Performed Under Direct Vision on Postoperative Pain in Spine Surgery
Status: COMPLETED
Conditions: Acute Pain
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TVEC in Patients With Cutaneous Squamous Cell Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma|Skin Cancer|Keratoacanthoma|Cutaneous Tumor|Skin Cancer, Squamous Cell|Lesion Skin
Interventions: DRUG: Injection of TVEC into target lesions - week 1-2|DRUG: Injection of TVEC into target lesions 3wks after 1st injection|DRUG: Injection of TVEC into target lesions 2wks after 2nd injection|DRUG: Injection of TVEC into target lesions 2wks after 3rd injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Nasopharyngeal (NP) and Lower Oesophageal (LO) Temperatures in Ventilated Children
Status: COMPLETED
Conditions: Child
Interventions: DEVICE: Nasopharyngeal and oesophageal temperature probes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Status: RECRUITING
Conditions: Sleep Initiation and Maintenance Disorders|Stress Disorders, Posttraumatic
Interventions: DRUG: Suvorexant|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistency Study After Hib-CRM (Cross-Reacting Material)197 or Hib-TT (Tetanus Toxoid) Vaccines in Chinese Children
Status: COMPLETED
Conditions: Meningitis, Epiglottitis, Pneumonia, Arthritis Caused by Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Hib-CRM197|BIOLOGICAL: Hib-TT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Duloxetine HCl 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel + Bevacizumab (Avastin) for the Treatment of Metastatic or Unresectable Angiosarcoma
Status: TERMINATED
Conditions: Angiosarcomas|Soft Tissue Sarcoma
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT