pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Salvage Lymph Node Dissection in Prostate Cancer Patients With Recurrence After Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Recurrent
Interventions: PROCEDURE: Salvage lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Invitation Procedure to the French Organized Colorectal Cancer Screening Program
Status: ENROLLING_BY_INVITATION
Conditions: Colorectal Cancer
Interventions: OTHER: Dispatch of the screening test along the invitation letter to the national colorectal cancer screening program|OTHER: Sending of a prior notification to the new entrants of the national program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Abuse|Cocaine-Related Disorders
Interventions: DRUG: Levodopa|DRUG: Carbidopa|BEHAVIORAL: Clinical Management|BEHAVIORAL: Relapse Prevention Therapy|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial
Status: RECRUITING
Conditions: Mitral Valve Insufficiency|Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous mitral valve repair|PROCEDURE: Surgical mitral valve repair/replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Novo Rapid 30 Mix Injection FlexPen® and Humalog 25 Mix Injection KwikPen® in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Complications|Diabetes Mellitus, Type 2
Interventions: DEVICE: KwikPen® and FlexPen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Gynomax® XL Ovule
Status: COMPLETED
Conditions: Trichomonal Vaginitis|Bacterial Vaginosis|Candidal Vulvovaginitis|Mixed Vaginal Infections
Interventions: DRUG: Gynomax® XL Vaginal Ovule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.
Status: RECRUITING
Conditions: Critical Limb Ischemia|Infrapopliteal Lesions
Interventions: DEVICE: Excimer Laser Combined with DCB|DEVICE: Angioplasty Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Patient Involvement in Alerts Management of Telemonitoring CPAP
Status: RECRUITING
Conditions: OSA
Interventions: DEVICE: New telemonitoring approach using 2 connected devices : Scanwatch connected watch + Asten&masanté application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Treatment With Candesartan vs Placebo in Genetic Carriers of Dilated Cardiomyopathy (EARLY-GENE Trial)
Status: RECRUITING
Conditions: Cardiomyopathy, Dilated
Interventions: DRUG: Candesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension
Status: TERMINATED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: Macitentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Theta Burst Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorder
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: Theta Burst Transcranial magnetic Stimulation using real MCF-B65 coil|DEVICE: Sham magnetic stimulation using sham MCF-B65 coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study Evaluating the Safety and Efficacy of IDP-107 in Patients With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Low Strength IDP-107|DRUG: High Strength IDP-107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Field Efficacy Of Insecticide Treated Uniforms And Skin Repellents for Malaria Prevention
Status: UNKNOWN
Conditions: Malaria
Interventions: OTHER: Ultra 30 Insect Repellent Lotion (30% Lipo DEET)|OTHER: Permethrin Factory-Treated Army Combat Uniforms|OTHER: Placebo lotion|OTHER: Army combat uniform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of Muscle Activity With Myofunctional Devices, Using Surface Electromyography
Status: UNKNOWN
Conditions: Class II Malocclusion
Interventions: DEVICE: functional apparatus|OTHER: Diagnosis and observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: KB5|OTHER: SG1|OTHER: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Prospective Trial of Frozen-and-Thawed Fecal Microbiota Transplantation for Recurrent Clostridium Difficile Infection
Status: TERMINATED
Conditions: Clostridium Difficile
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Umbilical Cord Serum Therapy on Improvement of Corneal Epithelial Defect Following Diabetic Vitrectomy
Status: UNKNOWN
Conditions: Corneal Epithelial Defect
Interventions: DRUG: conventional therapy plus umbilical cord serum eye drop|DRUG: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Aricept (donepezil hydrochloride)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate Hydrochloride Controlled-Release Tablets Augmentation Strategy for Patients With Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: Fluvoxamine+Methylphenidate hydrochloride|DRUG: Fluvoxamine+sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin, Couple Interaction and Wound Healing
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Syntocinon (Oxytocin) nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the TAXUS Liberté Stent for the Treatment of Long De Novo Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: TAXUS Liberté-SR|DEVICE: TAXUS™ Express
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial to Evaluate Suppressive Effect of High-Dose Valacyclovir Versus Once-Daily Valacyclovir on Persons With HSV-2
Status: COMPLETED
Conditions: Genital Herpes
Interventions: DRUG: valacyclovir|DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of Alemtuzumab to Treat B-cell Chronic Lymphocytic Leukemia
Status: SUSPENDED
Conditions: B-cell Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY)
Status: COMPLETED
Conditions: 15q Duplication Syndrome|CDKL5 Deficiency Disease
Interventions: DRUG: Soticlestat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for OA
Status: RECRUITING
Conditions: Osteoarthritis|Spinal Arthritis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Provent® on Obstructive Sleep Apnea During Continuous Positive Airway Pressure Therapy Withdrawal
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Provent®|DEVICE: Placebo-Provent®|PROCEDURE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Coach for Parents of Children and Adolescents With Chronic Pain
Status: COMPLETED
Conditions: Parents|Chronic Pain|Pediatric Disorder
Interventions: BEHAVIORAL: Mindfulness for Resilience in Illness: Support for Parents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genetic Variability in the Response to Warfarin at Baseline and During Induction of CYP2C9
Status: UNKNOWN
Conditions: Healthy Subjects
Interventions: DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Immunosuppressive Withdrawal After Pediatric Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Immune Tolerance|Immunosuppression|Liver Transplant; Complications
Interventions: DRUG: Tacrolimus or Cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Z8 OCT-controlled 2D vs 3D LASIK
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: 2D and 3D cutting method using a low energy Femtosecond laser LDV Z8 for LASIK flap cutting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Studies of Brain Structure and Function in MPS Disorders
Status: COMPLETED
Conditions: Mucopolysaccharidosis Type I|Mucopolysaccharidosis Type II|Mucopolysaccharidosis Type VI|Mucopolysaccharidosis Type IV|Mucopolysaccharidosis Type VII
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Investigating a PEGylated Recombinant Factor VIII (BAX 855) for Hemophilia A (PROLONG-ATE Study)
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Antihemophilic Factor (Recombinant) - Plasma/Albumin Free Method|BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: PEGylated Recombinant Factor VIII|BIOLOGICAL: PEGylated Recombinant Factor VIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurocognitive Correlates of Behavioral Treatment for Childhood Tic Disorders
Status: COMPLETED
Conditions: Tic Disorder
Interventions: BEHAVIORAL: Comprehensive Behavioral Intervention for Tics (CBIT)|BEHAVIORAL: Minimal Contact Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of X842 in Human: A Single/Multiple Ascending Dose Study
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Single ascending dose of X842|DRUG: Multiple ascending dose of X842|DRUG: Losec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Carcinoma, Squamous Cell
Interventions: RADIATION: standard dose prescription|RADIATION: FDG-PET guided gradient dose prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus Sintilimab for NSCLC Patients With First-generation EGFR-TKIs Drug Resistance Along With T790M Negative
Status: UNKNOWN
Conditions: Carcinoma|Non-small Cell Lung Cancer|Lung Neoplasm
Interventions: BIOLOGICAL: Sintilimab|DRUG: Anlotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Non-invasive and Invasive Blood Pressure Monitors
Status: RECRUITING
Conditions: Blood Pressure|Surgery|Intensive Care Unit
Interventions: DEVICE: ViTrack|PROCEDURE: Radial artery catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CRE8 in All Comers Patients
Status: COMPLETED
Conditions: Consecutive Subjects Who Are Suitable for a Coronary|Angioplasty of de Novo Lesion(s) in Native Coronary|Arteries Should be Screened for Eligibility.|A Total Number of 200 Patients Fulfilling the Selection|Criteria and Willing to Sign the Informed Consent Should|be Enrolled in the Trial.
Interventions: DEVICE: CR8 a drug eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FortiPhy: Protein Bioavailability, Satiety and Appetite
Status: UNKNOWN
Conditions: Protein-Energy Malnutrition
Interventions: DIETARY_SUPPLEMENT: Dairy protein porridge arm|DIETARY_SUPPLEMENT: Plant protein porridge arm|DIETARY_SUPPLEMENT: Control Porridge arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Trial of DI-B4 in Patients With Advanced CD19 Positive Indolent B-cell Malignancies
Status: COMPLETED
Conditions: Indolent B-cell Lymphoma|Chronic Lymphocytic Leukaemia|Waldenström Macroglobulinaemia
Interventions: DRUG: DI-B4
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Studying Biomarker Expression in Samples From Patients With Down Syndrome and Acute Myeloid Leukemia or Other Transient Myeloproliferative Disorder
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: RNA analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of a Remote Cognitive Remediation Therapy (CRT) Program on Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Cognitive Remediation Therapy Program (BrainHQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain and Visual Outcome in Intravitreal Bevacizumab Injection
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Anti-VEGF in quadrant 1|DRUG: Anti-VEGF in quadrant 2|DRUG: Anti-VEGF in quadrant 3|DRUG: Anti-VEGF in quadrant 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics, Safety and Efficacy of BIIL 284 BS in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Low dose of BIIL 284 BS tablets|DRUG: High dose of BIIL 284 BS tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Value of Next Generation Sequencing in Endocrine Therapy for Advanced Hormone Receptor Positive/HER-2 Negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm Female|Therapeutics|Mutation
Interventions: DIAGNOSTIC_TEST: Next Generation Sequencing (NGS) detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants
Status: RECRUITING
Conditions: Opiate Overdose|Fentanyl Overdose|Harm Reduction
Interventions: BEHAVIORAL: Fentanyl Test Strips
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Identify the Benefits CAREGIVERSPRO-MMD Platform Use Based on the Information and Communications Technology, Dedicated to the Support and Assistance of Dyads Living With Neurocognitive Diseases and Their Primary Caregivers
Status: UNKNOWN
Conditions: Cognitive Impairment, Mild|Dementia, Mild
Interventions: OTHER: Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantification of Myocardial Fibrosis in Aortis Stenosis
Status: NOT_YET_RECRUITING
Conditions: Aortic Valve Stenosis|Myocardial Fibrosis
Interventions: DIAGNOSTIC_TEST: High frame rate echocardiography|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Blood test|DIAGNOSTIC_TEST: ECG and Holter-ECG|DIAGNOSTIC_TEST: 6 min walking test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy, Interferon Alfa, and Radiation Therapy in Treating Patients Who Have Undergone Surgery For Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: Recombinant Interferon Alfa|DRUG: Cisplatin|DRUG: Fluorouracil|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Tradition Chinese Medicine in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Traditional Chinese Medicine|DRUG: Traditional Chinese Medicine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Bortezomib Treatment for Relapsed or Refractory Multiple Myeloma Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Su Jok Seed Therapy Application on Pain, Anxiety and Psychological Resilience in Patients Hospitalized in the Oncology Ward
Status: NOT_YET_RECRUITING
Conditions: Cancer|Cancer Pain
Interventions: DEVICE: Su-Jok
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Coronavirus Smell Therapy for Anosmia Recovery
Status: WITHDRAWN
Conditions: Anosmia
Interventions: DRUG: Budesonide|BEHAVIORAL: High-Concentration Essential Oil|DRUG: Placebo|BEHAVIORAL: Low-Concentration Essential Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular Surgery
Status: COMPLETED
Conditions: Inflammation and Pain Following Ocular Surgery
Interventions: DRUG: Omaveloxolone Ophthalmic Suspension 1.0%|DRUG: Omaveloxolone Opthalmic Suspension 0.5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Bacterial Infection|Benign Neoplasm|Malignant Neoplasm|Methicillin-Resistant Staphylococcus Aureus Infection|Myeloid Neoplasm|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: PROCEDURE: Chlorhexidine Gluconate Skin Cleanser|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Mild Soap Skin Cleanser|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Percutaneous Translumbar Vs Transhepatic Permcath
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Percutaneous translumbar and transhepatic permcath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hepatitis B Vaccine in Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: BIOLOGICAL: ENGERIX-B (HBV Vaccine)|BIOLOGICAL: Sci-B-Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy of EQ-778 on Upper Respiratory Tract Health Status in Healthy Adults
Status: RECRUITING
Conditions: Upper Respiratory Tract Infection
Interventions: OTHER: EQ-778|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase I/II Study of Mitoxantrone Liposome Combined With Chidamide in Relapsed/Refractory Peripheral T-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Relapsed and Refractory Peripheral T-cell Lymphoma
Interventions: DRUG: Mitoxantrone liposome combine with Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EtCO2 Level to Control Intraoperative Bleeding and Improve the Quality of Surgical Field Vision in Septorhinoplasty
Status: COMPLETED
Conditions: Anesthesia|Carbon Dioxide|Surgical Blood Loss
Interventions: DIAGNOSTIC_TEST: The amount of intraoperative bleeding|DIAGNOSTIC_TEST: Quality of the intraoperative surgical field|DIAGNOSTIC_TEST: Surgeon Satisfaction|DIAGNOSTIC_TEST: Heart rate|DIAGNOSTIC_TEST: Mean arterial pressure|DIAGNOSTIC_TEST: Peripheral oxygen saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Status: UNKNOWN
Conditions: Ventral Hernia|Abdominal Wall Defect
Interventions: PROCEDURE: Abdominal Wall Closure Force (N).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Mifepristone on Uterine Fibroids and Breast Tissue
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Mifegyne|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Consumption to Augment Adaptations to Concurrent Resistance and Aerobic Exercise Training
Status: RECRUITING
Conditions: Muscle Strength|Cardiorespiratory Fitness|Body Composition|Peanut Consumption
Interventions: OTHER: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Discontinuation or Continuation of Immunosuppressive Therapy in Participants With Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: BIOLOGICAL: Immunosuppressive Therapy|BIOLOGICAL: Immunosuppressive Therapy|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunoclassification of Psoriasis: a Strategy for Precision Medicine
Status: RECRUITING
Conditions: Immunoclassification|Psoriasis
Interventions: BIOLOGICAL: adalimumab, secukinumab, ixekizumab, guselkumab, Jak inhibitors, methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety Profile and Ability of TW1025 Oral Solution to Decrease Fatigue
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Fatigue
Interventions: DIETARY_SUPPLEMENT: TW1025|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creatine, Exercise and Inflammatory Markers in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Creatine|OTHER: Walking Exercise|DIETARY_SUPPLEMENT: placebo (maltodextrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Essential Amino Acid-enriched Whey and Carbohydrate Co-ingestion on Protein Kinetics
Status: ACTIVE_NOT_RECRUITING
Conditions: Energy Deficit
Interventions: DIETARY_SUPPLEMENT: EAA+W & Carbohydrate|DIETARY_SUPPLEMENT: EAA+W & EAA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ZD4054 (Zibotentan) Phase II Non-Small Cell Lung Cancer Study
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: ZD4054|DRUG: Pemetrexed|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls
Status: ACTIVE_NOT_RECRUITING
Conditions: Critical Illness|Cardiac Arrest|Sepsis|Influenza|Covid19|Trauma
Interventions: DIAGNOSTIC_TEST: Blood collection|DIAGNOSTIC_TEST: Blood collection, serial sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Investigate the Molecular Mechanism of Traditional Chinese Medicine Constitution Using Next-generation Sequencing in Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Danggui Buxue Tang|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Nutritional Supplement on the Recovery of the Nutritional Status of Patients With Spontaneous Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures|Malnutrition
Interventions: DIETARY_SUPPLEMENT: FontActiv Superprotein/Hypercaloric Fiber|DIETARY_SUPPLEMENT: Carbohydrates and C Vitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NMES to Improve Hip Abductor Strength and Balance
Status: COMPLETED
Conditions: Postural Balance
Interventions: OTHER: Neuromuscular electrical stimulation (NMES)|OTHER: Multi-Modality Balance Intervention (MMBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Release Versus Immediate Release Tacrolimus Following Renal Allograft Failure to Reduce Allosensitisation
Status: UNKNOWN
Conditions: Kidney Transplant Failure|Allosensitization|Immunosuppression
Interventions: DRUG: Envarsus Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial to Examine the Effect of Two Doses of GRI-0621 in Patients With Chronic Liver Disease
Status: TERMINATED
Conditions: Chronic Liver Disease
Interventions: DRUG: Placebo Comparator|DRUG: Active Comparator:4.5mg GRI-0621|DRUG: Active Comparator: 6.0mg GRI-0621
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Surfactant Through Nebulizer Mask on Clinical Outcomes in Covid-19 Patients
Status: UNKNOWN
Conditions: COVID-19|Respiratory Distress Syndrome|Surface-Active Agents
Interventions: DRUG: exogenous surfactant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Coaching for Patients Waiting for Hip or Knee Replacements
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Hip|Osteo Arthritis Knee
Interventions: OTHER: Health Coach (Health coaching)|OTHER: Digital Toolkit (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Self-Fixating vs Non-Fixating Hernia Mesh
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Use of self-fixating mesh for inguinal hernia repair|PROCEDURE: Use of non-fixating mesh for inguinal hernia repair|PROCEDURE: Absorbable tacks may be used in hernias >2cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs
Status: COMPLETED
Conditions: Epidermolysis Bullosa
Interventions: DRUG: Thymoglobulin|DRUG: Cyclophosphamide|DRUG: Fludarabine|RADIATION: Total Body Irradiation|PROCEDURE: Bone marrow infusion|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Donor mesenchymal stem cell infusions|DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: JNJ-42847922 20mg|DRUG: JNJ-42847922 40mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation With GKEX Sports Probiotic Combo for Muscle Gain and Fat Loss Assessment
Status: COMPLETED
Conditions: Sport Nutrition|Probiotic
Interventions: DIETARY_SUPPLEMENT: GKEX|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of the Efficacy, Safety and Tolerability of Topical 2PX (Strontium Chloride Hexahydrate) in Patients With Chronic, Moderate-to-severe Lower Limb Post-amputation Stump Pain
Status: UNKNOWN
Conditions: Stump Pain
Interventions: DRUG: 2PX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Derived MSCs Transplantation in Patient With Spinal Cord Injury.
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: OTHER: Autologous Adipose Derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes
Status: COMPLETED
Conditions: Glucose Intolerance|Type 2 Diabetes Mellitus|Metabolic Syndrome
Interventions: DRUG: Vitamin D3 2,000 IU orally once daily|DRUG: Calcium Carbonate 400 mg orally twice daily|DRUG: Vitamin D3-Placebo|DRUG: Calcium-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of SHR3680 in Metastatic Castration-Resistant Prostate Cancer Patients
Status: UNKNOWN
Conditions: Hormone Refractory Prostate Cancer|Metastatic Prostate Carcinoma
Interventions: DRUG: SHR3680
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Treatment and Metabolic Control in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Periodontal Disease
Interventions: PROCEDURE: non-surgical periodontal treatment|PROCEDURE: Supragingival biofilm control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Hypertonic Saline for Inpatient Use in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: hypertonic saline|DRUG: standard saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, (DURVA+ Study)
Status: RECRUITING
Conditions: Locally Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Capecitabine|DRUG: Carboplatin|PROCEDURE: Computed Tomography|BIOLOGICAL: Durvalumab|PROCEDURE: Echocardiography|DRUG: Gemcitabine Hydrochloride|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2484595 in Japanese Subjects
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: LY2484595|DRUG: Placebo|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema)
Status: COMPLETED
Conditions: Atopic Dermatitis|Eczema
Interventions: DRUG: Nanocrystalline silver cream (NPI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose Escalation and Dose Expansion Trial of NP-101 in Patients With Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: NP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of ONO-8539 on Acid-Induced Oesophageal Hypersensitivity in Healthy Volunteers
Status: COMPLETED
Conditions: Acid Reflux
Interventions: DRUG: ONO-8539|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on Power Prenatal Vitamins for Males on YO Score At-home Sperm Test Results
Status: RECRUITING
Conditions: Spermatogenesis and Semen Disorders|Infertility, Male
Interventions: DIETARY_SUPPLEMENT: Power Prenatal for Sperm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of the Combination of GSK573719 and GW642444 in Subjects With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: 500mcg/25mcg once daily|DRUG: Placebo once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Non-alcoholic Fatty Liver Disease|Efficacy
Interventions: DRUG: Combination of Pioglitazone and Metformin Tablets|DRUG: Metformin Hydrochloride Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose PCSK9 Inhibitor Combined With Stains on Serum Lipids in Chinese Population With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Statin|DRUG: PCSK9 inhibitor|DRUG: PCSK9 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Characterize the Pharmacokinetics of 3 Marketed Products Containing 200 mg Guaifenesin in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Vicks Cough Syrup for Chesty Coughs|DRUG: Robitussin Extra Strength Chest Congestion|DRUG: Organ-I- NR tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty
Status: RECRUITING
Conditions: Remimazolam|Emergence Delirium|Rhinoplasty
Interventions: DRUG: Remimazolam 20 MG Injection [Byfavo]|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: Vaccine + extension of the ATI period|OTHER: Placebo + extension of the ATI period
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Scenario-based Education Initiative and OSCE for Recognition and Management of Delirium
Status: RECRUITING
Conditions: Delirium
Interventions: BEHAVIORAL: OSCEs|BEHAVIORAL: Lecture|BEHAVIORAL: E-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intradermal Versus Intramuscular Trivalent Influenza Vaccine in Adult Lung Transplant Recipients
Status: COMPLETED
Conditions: Influenza Virus|Influenza Vaccine
Interventions: BIOLOGICAL: Vaxigrip (Aventis-Pasteur Canada)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind, Vehicle-Controlled Study in Subjects With Seborrheic Keratosis
Status: COMPLETED
Conditions: Seborrheic Keratosis
Interventions: DRUG: A-101 Solution|OTHER: Vehicle Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MGuard Stent and Microcirculation
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Atherosclerosis|Cardiovascular Diseases
Interventions: DEVICE: MGuard stent|DEVICE: Drug eluting stent and bare metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Tislelizumab|DRUG: Interleukin-2|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Neoplasm|Renal Cancer|Kidney Cancer
Interventions: DRUG: Yttrium-90 conjugated chimeric G250 (^90Y-DOTA-cG250)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pericapsular Exparel for Pain Relief in Bunionectomy and Related Procedures
Status: TERMINATED
Conditions: Bunion|Hallux Rigidus
Interventions: DRUG: 0.5% ropivacaine|DRUG: Exparel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Pharmacokinetics and Effectiveness of AGS-16C3F Monotherapy in Subjects With Renal Cell Carcinoma (RCC) of Clear Cell or Papillary Histology
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Renal Cell Carcinoma of Papillary Histology|Renal Cell Carcinoma With Clear Cell Histology|Renal Cell Carcinoma With Non-Clear Cell Histology
Interventions: DRUG: AGS-16C3F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib Plus Nivolumab and Ipilimumab in Women With Recurrent Gynecologic Carcinosarcoma
Status: WITHDRAWN
Conditions: Carcinosarcoma of Ovary|Carcinosarcoma of Uterus|Carcinosarcoma of Vagina
Interventions: DRUG: Cabozantinib|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cellular Immunotherapy for Septic Shock
Status: UNKNOWN
Conditions: Septic Shock|Sepsis|Pathologic Processes|Shock|Infection|Systemic Inflammatory Response Syndrome|Inflammation
Interventions: BIOLOGICAL: Allogeneic Bone Marrow-Derived Human Mesenchymal Stem Cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Of CP-675,206 or Best Supportive Care Immediately After Platinum-Based Therapy For Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: CP-675,206|DRUG: best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644)
Status: COMPLETED
Conditions: Glioblastoma|Astrocytoma
Interventions: DRUG: Temozolomide|DRUG: Semustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Diffuse Astrocytoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Adult Oligodendroglioma|Recurrent Adult Brain Tumor
Interventions: DRUG: erlotinib hydrochloride|DRUG: isotretinoin|OTHER: laboratory biomarker analysis|GENETIC: protein expression analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Different Doses Dexmedetomidine Infusion on Lung Mechanics and Oxygenation in Obese Patients
Status: COMPLETED
Conditions: Obesity; Drug
Interventions: DRUG: Dexmedetomidine Injection [Precedex]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT