pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Albiglutide|DRUG: Matching albiglutide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Oral Mucositis Using Photobiomodulation Therapy
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: Photobiomodulation Therapy (PBM)|OTHER: Pain and Oral Function Assessment|OTHER: Parent-Reported Satisfaction Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of IBS Angel in Patients With Pulmonary Artery Stenosis
Status: RECRUITING
Conditions: Pulmonary Artery Stenosis
Interventions: DEVICE: Iron Bioresorbable Scaffold System (IBS Angel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SIMPLIFY the Hand Hygiene Procedure - Three Steps Versus Six Steps for Performing Hand Hygiene (SIMPLIFY Study)
Status: NOT_YET_RECRUITING
Conditions: Hand Hygiene
Interventions: PROCEDURE: Study intervention: 3-step hand hygiene technique|PROCEDURE: Control intervention: 6-step hand hygiene technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Azithromycin Insulin Diet Intervention Trial in Type 1 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus|Metabolic Disease|Glucose Metabolism Disorders|Endocrine System Diseases|Juvenile Diabetes|Insulin Dependent Diabetes|Type 1 Diabetes Mellitus|Inflammation|Diet Modification
Interventions: DRUG: Azithromycin Monohydrate|DRUG: Insulin Lispro|BEHAVIORAL: Dietician support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Hsp90 Inhibitor AUY922 in Treating Patients With Previously Treated Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Hsp90 inhibitor AUY922|DRUG: pemetrexed disodium|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Involvement of 15q11 - q13 Chromosome Region and CYFIP1 Gene in Autism. Attempt a Genotype-phenotype Correlation
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: GENETIC: Genetic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiological Flow of Liquids in Head and Neck Cancer Patients: A Pilot Study
Status: COMPLETED
Conditions: Deglutition Disorders|Oropharynx Cancer
Interventions: OTHER: Starch-based Thickened Liquids|OTHER: Xanthan-gum Thickened Liquids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Gene Therapy Protocol for the Treatment of Retinal Dystrophy Caused by Defects in RPE65
Status: COMPLETED
Conditions: Leber Congenital Amaurosis
Interventions: DRUG: rAAV2/4.hRPE65
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Comparison of the Addiction Liability of Hydrocodone and Sustained Release Morphine
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Markers of Abuse Liability, Neuropsych Testing, and Cue Reactivity|DRUG: ER Morphine|DRUG: hydrocodone plus acetaminophen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Rehabilitation Program in Improving Cardiorespiratory Fitness in Stage 0-III Breast Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor|Stage 0 Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: OTHER: Educational Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Of The Efficacy And Safety Of CP-601,927 Augmentation Of Antidepressant Therapy In Major Depression
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: CP-601,927|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brain-injured Patients Extubation Readiness Study
Status: RECRUITING
Conditions: Mechanical Ventilator Weaning|Acute Brain Injury|Altered Level of Consciousness|Mechanical Ventilation|Airway Control
Interventions: PROCEDURE: Extubation readiness clinical score|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Brain on Whole Body Hyperthermia: A Neuroimaging Study
Status: COMPLETED
Conditions: Major Depression
Interventions: DEVICE: High intensity whole-body infrared heating|DEVICE: Low intensity whole-body infrared heating|DEVICE: Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG)|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intestinal Decontamination With Rifaximin. The Inflammatory and Circulatory State in Patients With Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis|Ascites
Interventions: DRUG: Rifaximin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare Overall Survival in Medicare Patients With Metastatic Breast Cancer Treated With a Medicine Called Palbociclib in Combination With Aromatase Inhibitor and Aromatase Inhibitor by Itself.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib|DRUG: Aromatase Inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Immunogenicity, and Safety of TURKOVAC Vaccine Versus the CoronaVac Vaccine Against COVID-19 in Healthy Adolescent
Status: COMPLETED
Conditions: COVID-19|Sars-CoV-2 Infection
Interventions: BIOLOGICAL: TURKOVAC|BIOLOGICAL: CoronaVac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing a Nature-based Socila Intevention on Loneliness: the RECETAS-PRG Trial
Status: RECRUITING
Conditions: Loneliness
Interventions: BEHAVIORAL: Nature-based social intervention (NBIS)|BEHAVIORAL: Usual care + menu with nature based activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing 0.3% Adapalene Topical Gel to Differin® 0.3% Adapalene Topical Gel
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: adapalene 0.3% topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effect of Esomeprazole on SYN-004 Degradation of Ceftriaxone In Adults With an Ileostomy
Status: COMPLETED
Conditions: Healthy Volunteers With Ileostomy
Interventions: DRUG: SYN-004|DRUG: Esomeprazole|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct-acting Antiviral Therapy to Prevent HCV Infection for HCV Positive Donor to HCV Negative Recipient Kidney Transplant
Status: WITHDRAWN
Conditions: Renal Failure Chronic|Hepatitis C
Interventions: DRUG: Zepatier|DRUG: Zepatier plus Sofosbuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCI
Status: COMPLETED
Conditions: Myocardial Ischemia|Coronary Artery Disease|Endothelial Dysfunction
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Superior Hypogastric Plexus Blockade in Laparoscopic Hysterectomy
Status: UNKNOWN
Conditions: Superior Hypogastric Plexus Block|Hysterectomy|Minimally Invasive Surgery|Laparoscopy|Pain, Postoperative|Gynecologic Disease
Interventions: PROCEDURE: Procedure/Surgery: superior hypogastric block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long Term Clinical Efficacy of Thrombectomy Devices in Acute ST Elevation Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: thrombectomy devices|DEVICE: angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meal-regulated Substrate Metabolism, Influence of Obesity and IL-6
Status: COMPLETED
Conditions: Obesity|Healthy
Interventions: DRUG: Tocilizumab|DRUG: Saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility Study to Develop Sentinel Lymph Node Mapping in Rectal Cancer Patients
Status: WITHDRAWN
Conditions: Rectal Cancer
Interventions: OTHER: Intraoperative Mobile Gamma Camera imaging|DRUG: Endoscopic injection of 99mTc-sulfur colloid|OTHER: Endoscopic injections of Spot|PROCEDURE: Preoperative flexible sigmoidoscopy|RADIATION: SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acceptability of Lipid-Based Nutrient Supplements (LNS) for Women and Infants
Status: COMPLETED
Conditions: Anemia|Malnutrition
Interventions: DIETARY_SUPPLEMENT: LNS-20gM or LNS-P&L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety and Efficacy of Teropavimab and Zinlirvimab in Combination With Lenacapavir (GS-6207) in Virologically Suppressed Adults With HIV-1 Infection
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Oral Lenacapavir|DRUG: Subcutaneous Lenacapavir|DRUG: Teropavimab|DRUG: Zinlirvimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-concept Study of Lunsekimig Compared With Placebo in Adults With Chronic Rhinosinusitis With Nasal Polyps
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: lunsekimig|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BIA 9-1067 on the Pharmacokinetics and Pharmacodynamics of Warfarin
Status: COMPLETED
Conditions: Parkinson's Disease (PD)
Interventions: DRUG: BIA 9-1067|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Leucovorin|DRUG: Methotrexate|DRUG: Procarbazine|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Clarithromycin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Immunogenicity and Safety of GSK Biologicals' Infanrix-IPV/Hib Vaccine Administered as a Three-dose Vaccination Course at 3, 4.5 and 6 Months of Age and a Booster Dose at 18 Months of Age in Healthy Infants in Russia
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Infanrix-IPV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Relationship Between Serum PSA Levels and WBC, Delta Neutrophil Index (DNI) and Other Hematological Parameters
Status: COMPLETED
Conditions: Prostate Infection|Prostate Disease|Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Serum PSA,Delta Neutrophil Index(DNI),WBC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C-GSK1265744 Administered as a Single Oral Dose and a Study to Describe the Pharmacokinetics of a Supratherapeutic Dose of GSK1265744 in Healthy Adult Subjects
Status: COMPLETED
Conditions: HIV-associated Lipodystrophy Syndrome
Interventions: DRUG: GSK1265744B (sodium salt) containing 14C-GSK1265744B|DRUG: 150 mg GSK1265744B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Pharmacokinetics and Safety of Two SAR231893 (REGN668) Drug Products in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: SAR231893 (REGN668) DP1|BIOLOGICAL: SAR231893 (REGN668) DP2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Or v IV Antibiotics for Infection
Status: UNKNOWN
Conditions: Joint Infection
Interventions: DRUG: Bactrim|DRUG: Cefadroxil|DRUG: Doxycycline Hcl|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alternation of Non-alcoholic Fatty Liver Disease (NAFLD) and Cardiovascular Risks After Liftestyle Modification: A Ultrasound Attenuation Imaging-Based Study
Status: TERMINATED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Dietitian led life style modification intervention|BEHAVIORAL: Conventional care (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HY1272 in Patients With Locally Advanced or Metastatic Solid Tumors or Locally Advanced or Metastatic EGFRm+ NSCLC
Status: NOT_YET_RECRUITING
Conditions: NSCLC Stage IV
Interventions: DRUG: HY1272
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APRiCOT-L: Study to Evaluate Efficacy and Safety of Apricoxib With Erlotinib in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Non Small Cell Lung Cancer
Interventions: DRUG: apricoxib/erlotinib|DRUG: erlotinib/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Photopheresis in the Treatment of Erythrodermic MF and SS
Status: WITHDRAWN
Conditions: Lymphoma, T-Cell, Cutaneous|Mycosis Fungoides/Sezary Syndrome
Interventions: DRUG: Methoxsalen|DEVICE: THERAKOS CELLEX Photopheresis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Blocks for Infants and Children for Postoperative Pain Control
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study and 12 Month Extension to Evaluate Two Investigational Drugs in Postmenopausal Women With Osteoporosis (MK-0217-907)
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: MK0217, alendronate sodium/Duration of Intervention: 12 mo|DRUG: Comparator: risedronate / Duration of Intervention: 12 mo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Beginning a Renal Replacement Therapy on Obstructive Sleep Apnea in End Stage Renal Disease Patients
Status: SUSPENDED
Conditions: Obstructive Sleep Apnea|End Stage Renal Disease
Interventions: PROCEDURE: Renal replacement therapy|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh
Status: UNKNOWN
Conditions: Wound Healing|Wound Infection|Pain|Pruritus|Cicatrix
Interventions: DEVICE: Acticoat Absorbent|DEVICE: BCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transperineal Ultrasonography and Premature Rupture of Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of the Membranes
Interventions: OTHER: PAMG-1 Immunoassay|DEVICE: Ultrasound transperineal assessment|DEVICE: Ultrasound amniotic fluid index measurement|OTHER: Speculum examination|OTHER: Nitrazine test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Evaluation of Performance and Safety of the Anchorsure® Transvaginal Device for Surgical Treatment of Apical Prolapse in Women
Status: RECRUITING
Conditions: Prolapse; Female|Prolapse Uterovaginal|Prolapse; Cervix
Interventions: DEVICE: The Anchorsure System®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysing the Psychosocial Effects of COVID-19 Pandemic on Dental Professionals Using the Turkish Version of the Fear of COVID-19 and Coronavirus Anxiety Scales
Status: COMPLETED
Conditions: COVID-19 Pandemic
Interventions: BEHAVIORAL: The psychosocial effects of COVID-19 pandemic on dental professionals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ambu Aura GainTM Guided vs Non Guided in Edentulous Ambu Aura GainTM Without Gastric Tube in Endontolous Patient
Status: COMPLETED
Conditions: Oropharyngeal Leak Pressure
Interventions: DEVICE: Gastric Tube|DEVICE: No gastric Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: XLHA+CoQ10|DEVICE: Hyaluronic acid (HA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contagious Itch, Disgust and Empathy in Patients and Medical Staff
Status: COMPLETED
Conditions: Contagious Itch
Interventions: OTHER: 7-items-questionnaires addressing CI, disgust and empathy|OTHER: Saarbrucken Personality questionnaire (SPQ) addressing empathy.|OTHER: 10-items-questionnaire addressing previous dermatological conditions, intensity of itch|OTHER: ItchyQol-questionnaire composed of 22 items addressing itch-related symptoms, functions and emotions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Leukemia|Lymphoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: talotrexin|PROCEDURE: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers to Prove That Two Rotigotine Patches From Different Manufacturing Sites Deliver Equivalent Drug Amount to the Body
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: rotigotine transdermal patch (Neupro®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stereotactic Radiosurgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: PROCEDURE: computed tomography|RADIATION: fludeoxyglucose F 18|RADIATION: hypofractionated radiation therapy|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIb Study to Evaluate the Safety and Efficacy of Gemigliptin in Type 2 Diabetes Mellitus Patients With Moderate or Severe Renal Impairment(GUARD Study)
Status: COMPLETED
Conditions: Type 2 DM Patients With Moderate or Severe Renal Impairment
Interventions: DRUG: Gemigliptin|DRUG: Placebo to Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases
Status: COMPLETED
Conditions: Metastatic Triple Negative Breast Cancer|Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Talimogene Laherparepvec|BIOLOGICAL: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: DEVICE: Sculptra Aesthetic 8ml|DEVICE: Sculptra Aesthetic 5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Surgical Approaches in Patients of Early-stage Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasm|Laparotomy|Laparoscopy|Survival|Mortality|Morbidity|Quality of Life|Pelvic Floor Disorders|Cost-Benefit Analysis
Interventions: PROCEDURE: Laparotomic radical hysterectomy|PROCEDURE: Laparotomic radical trachelectomy|PROCEDURE: Laparoscopic radical hysterectomy|PROCEDURE: Laparoscopic radical trachelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
Status: RECRUITING
Conditions: Anesthesia Recovery Period|Postoperative Complications
Interventions: DRUG: Dexmedetomidine and propofol|DRUG: Dexmedetomidine and desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the 95% Effective Dose of Ciprofol for Adjunctive Sedation Undergoing Knee Arthroplasty in Elderly People
Status: RECRUITING
Conditions: Sedation|ED95|Knee Arthroplasty
Interventions: DRUG: Ciprofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Transversus Abdominis Plane (TAP) Block After Laparoscopic Colon Surgery
Status: COMPLETED
Conditions: Laparoscopic Colon Surgery
Interventions: PROCEDURE: Transversus abdominis plane (TAP) block|PROCEDURE: Placebo TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib, TQB2450 (PD-L1 Inhibitor), and Albumin-bound Paclitaxel Regimens in the Treatment of GC/GEJA
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Adenocarcinoma of Esophagogastric Junction
Interventions: DRUG: Anlotinib|DRUG: TQB2450|DRUG: Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Kidney Injury After Cardiac Surgery
Status: TERMINATED
Conditions: Cardiac Surgical Procedures|Extracorporeal Circulation; Complications|Acute Kidney Injury
Interventions: DEVICE: Colloid priming solution for ECC circuit|DEVICE: Standard priming solution for ECC circuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Accuracy of Commercially Available Heart Rate Monitors II
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Fit Bit Blaze Heart Rate Monitoring Device|DEVICE: Garmin Forerunner 235 Heart Rate Monitoring Device|DEVICE: Tom Tom Spark Cardio Heart Rate Monitoring Device|DEVICE: Apple Watch Heart Rate Monitoring Device|DEVICE: Scosche Rhythm + Heart Rate Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Clinical Trial of the Combination of Trastuzumab (Herceptin) and Tanespimycin in Patients With Solid Tumors and Her2 Positive Metastatic Breast Cancer That Have Previously Failed Herceptin
Status: COMPLETED
Conditions: Solid Tumors|Breast Cancer
Interventions: DRUG: Tanespimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pressure Regulation on Optic Nerve Sheath Diameter
Status: COMPLETED
Conditions: Optic Nerve Sheath Diameter
Interventions: OTHER: RALRP under lower mean BP|OTHER: RALRP under lower mean BP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion (Part A)
Status: COMPLETED
Conditions: Essential Fatty Acid Deficiency (EFAD)
Interventions: DRUG: Clinolipid|DRUG: Intralipid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin (IL)-1 Blockade in Acute Heart Failure (Anakinra ADHF)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Anakinra (high dose)|DRUG: Anakinra (standard dose)|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Efficiency of Acupuncture in Non Chronified Pain Patients With TMDs
Status: UNKNOWN
Conditions: Temporomandibular Disorders
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SARCOLOWDOSE : Ultra-low Dose CT Scan and MRI in Thoracic Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis, Pulmonary
Interventions: OTHER: Patients with thoracic sarcoidosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Camrelizumab in Combination With Apatinib Mesylate, Paclitaxel-albumin and S-1 for Translational Treatment of Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Camrelizumab+Apatinib+Paclitaxel-albumin+S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipiodol-TACE With Idarubicin for Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Idarubicin Hydrochloride for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Magnesium Sulfate in Pediatric Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Nebulized Magnesium Sulfate|OTHER: Nebulized normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-course Radiotherapy Combined With Furoquintinib and PD-1 Monoclonal Antibody
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Short-course radiotherapy combined with furoquintinib and PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Epidermal Micrografts for Wound Healing After Mohs or Excisional Surgery for Skin Cancer
Status: UNKNOWN
Conditions: Neoplasm of Skin
Interventions: DEVICE: Momelan Technologies Epidermal Graft Harvesting System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Axillary Block in Association With Analgesic Truncal Blocks at the Elbow for Wrist Surgery.
Status: COMPLETED
Conditions: Wrist Fracture
Interventions: PROCEDURE: Axillary brachial plexus block with a long-acting local anesthetic|PROCEDURE: Axillary brachial plexus block with a short-acting local anesthetic + Analgesic block at the elbow with a long-acting local anesthetic|DRUG: Ropivacaine|DRUG: Ropivacaine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Meaning-Centered Intervention for Muslim Patients Who Are Being Treated for Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer
Interventions: OTHER: Masterful supportive care|OTHER: Attention control supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Allied Healthcare in Patients Recovering From COVID-19
Status: UNKNOWN
Conditions: Covid19|Allied Health Professionals|Primary Care|Retrospective Cohort|PROMs|Performance Measures|Prospective Cohort|National Dutch Program
Interventions: OTHER: Patients recovering from COVID19 receive usual care by allied health professionals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lovenox 30 mg Twice Daily (BID) Versus 40 mg Once Daily (QD)
Status: RECRUITING
Conditions: Trauma|Surgery|Deep Vein Thrombosis (DVT)|Thromboembolic Events
Interventions: DRUG: Enoxaparin Sodium Injection 30 mg BID|DRUG: Enoxaparin Sodium Injection 40 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasm Carcinoma in Situ Adenocarcinoma
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation
Status: COMPLETED
Conditions: End-stage Renal Failure|Graft Rejection
Interventions: DRUG: Tacrolimus (Kidney transplant maintenance immunosuppression)|DRUG: Kidney transplant maintenance immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Functional Evaluation of Modified Studer and Modified Spiral Orthotopic Ileal Neobladders After Radical Cystectomy.
Status: NOT_YET_RECRUITING
Conditions: Orthotopic Neobladders
Interventions: PROCEDURE: modified Studer ileal neobladder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries
Status: SUSPENDED
Conditions: Critical Limb Ischemia
Interventions: DEVICE: Stellarex DCB|DEVICE: PTA Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Barbershop Talk: Reducing Excessive Alcohol Consumption Among Black Men
Status: RECRUITING
Conditions: Drinking Behavior|Drinking Excessive|Drinking
Interventions: BEHAVIORAL: SBIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ibrutinib in Combination With Corticosteroids vs Placebo in Combination With Corticosteroids in Participants With New Onset Chronic Graft Versus Host Disease (cGVHD)
Status: COMPLETED
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: ibrutinib|DRUG: Placebo|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion for the Induction of General Anesthesia in Elective Surgery Subjects
Status: COMPLETED
Conditions: Induction of Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wearability, Saefty and Usability Assessment for the Upper Limb Exoskeleton BRIDGE/EMPATIA
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DEVICE: BRIDGE/EMPATIA exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Preoperative SGB on POAF After VATS
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: stellate ganglion blocks|DRUG: Ropivacaine|DRUG: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multimodal Imaging in Vitreo-retinal Surgery and Macular Dystrophies
Status: RECRUITING
Conditions: Macular Holes|Epiretinal Membrane|Retinal Detachment|Macular Dystrophies
Interventions: DIAGNOSTIC_TEST: Biometry|DIAGNOSTIC_TEST: Retinography (Color) + Autofluorescence (AF)|DIAGNOSTIC_TEST: OCT B-scan and OCT angiography (OCTA)|DIAGNOSTIC_TEST: Microperimetry|DIAGNOSTIC_TEST: Electrophysiological exams
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Navigation Laser Versus Traditional Laser Photocoagulation for Mild Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Navigation laser|DEVICE: Traditional laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Being a Parent: Evaluation of a Parenting Intervention for Childhood Behavioral Problems
Status: COMPLETED
Conditions: Childhood Behavior Problems|Positive Parenting Skills|Parental Concerns|Parents' Sense of Competence
Interventions: BEHAVIORAL: Being a Parent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Status: WITHDRAWN
Conditions: Cytomegaloviral Infection|Hematopoietic and Lymphoid System Neoplasm
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Biospecimen Collection|BIOLOGICAL: CMV pp65 Peptide-loaded Alpha-type-1 Polarized Dendritic Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of FITpatch Compared to Standard Opioid Treatment in Cancer Pain (FT-015-IN)
Status: COMPLETED
Conditions: Standard Opioid Analgesic Treatment of Cancer-related Chronic Pain.
Interventions: DRUG: Fentanyl (Matrifen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Excercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|Physical Activity|Coronary Artery Bypass Graft Surgery
Interventions: OTHER: Preoperative Exercise Training|OTHER: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Status: RECRUITING
Conditions: Bladder Carcinoma|Ureter Carcinoma|Renal Pelvis Carcinoma|Non-small Cell Lung Cancer|Invasive Breast Carcinoma|Cutaneous Melanoma|Esophageal Carcinoma|Gastroesophageal Junction Carcinoma|Gastric Adenocarcinoma|Pancreatic Adenocarcinoma|Squamous Cell Carcinoma of the Head and Neck|Epithelial Ovarian Carcinoma|Fallopian Tube Carcinoma|Endometrial Carcinoma|Renal Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: Guardant Reveal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP14012 After Oral Administration in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWP14012|DRUG: Placebo|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Nigella Sativa on Nonalcoholic Steatohepatitis and Steatosis
Status: UNKNOWN
Conditions: Nonalcoholic Steatohepatitis|Liver Steatosis
Interventions: DIETARY_SUPPLEMENT: Nigella Sativa|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Corticosteroid vs. Ketorolac Shoulder Injections: A Prospective Double-Blinded Randomized Trial
Status: TERMINATED
Conditions: Full Thickness Rotator Cuff Tear|Rotator Cuff Tendinitis
Interventions: DRUG: Ketorolac|DRUG: Marcaine (placebo)|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Halliwick Hydrotherapy and Snoezelen
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autism|Sensory Disorder
Interventions: OTHER: Hydrotherapy- Snoezelen|OTHER: Snoezelen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: STSA-1002 injection|DRUG: Placebo|DRUG: STSA-1002 injection|DRUG: Placebo|DRUG: STSA-1002 injection|DRUG: Placebo|DRUG: STSA-1002 injection|DRUG: Placebo|DRUG: STSA-1002 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Acute Bioavailability of EPA and DHA From a DietarySupplement in Healthy Men and Women
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Wax Ester Marine Oil|OTHER: Ethyl Ester Marine Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glutamine for the Treatment of Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Diarrhea-Predominant Irritable Bowel Syndrome
Interventions: DRUG: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Tolerability of Ziprasidone vs. Clozapine for the Treatment of Schizophrenia in Patients Who Continue to Have Symptoms on or Cannot Tolerate Other Antipsychotic Drugs
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Clozapine|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Purinostat Mesylate for Injection in the Treatment of Diffuse Large B-cell Lymphoma (DLBCL)
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma，DLBCL
Interventions: DRUG: PM 8.4 mg/m2|DRUG: PM 11.2 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Severe Acute Respiratory Syndrome CoV 2 COVID-19 Survey and Vaccination Coverage in the Sickle Cell Population in Ile-De-France
Status: UNKNOWN
Conditions: Sickle Cell Disease
Interventions: OTHER: severe acute respiratory syndrome CoV-2 serology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Demonstrate Consistency of Three Lots of a Live-attenuated Chikungunya Virus Vaccine Candidate in Healthy Adults
Status: COMPLETED
Conditions: Chikungunya Virus Infection
Interventions: BIOLOGICAL: Biological Vaccine VLA1553
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Variable Frequency Stimulation of Subthalamic Nucleus for Freezing of Gait in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PORTAS 2, Comparing Venae Sectio Versus Punction of Vena Subclavia for Insertion of a Totally Implantable Access Port
Status: COMPLETED
Conditions: Cancer
Interventions: PROCEDURE: Venae sectio|PROCEDURE: Punction of V. subclavia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIL Therapy in Metastatic Melanoma and IL2 Dose Assessment
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|GENETIC: Tumour Infiltrating Lymphocytes|DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyridostigmine as Immunomodulator in People Living With HIV
Status: SUSPENDED
Conditions: HIV-1-infection|CD4+ T Lymphocytopenia|Immune Deficiency|Immuno-senescence
Interventions: DRUG: Pyridostigmine Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma
Status: AVAILABLE
Conditions: Neuroblastoma|Pheochromocytoma
Interventions: DRUG: 131-I-meta-iodobenzylguanidine
Study Type: EXPANDED_ACCESS
Clinical trial: Replacing Canes With an Elasticated Orthosis in Chronic Stroke Patients: The Influence on Gait and Balance. A Series of N-of-1 Trials
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Cane|DEVICE: Elasticated worn orthotic-garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT