pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal Endoscope
Status: COMPLETED
Conditions: Using Copolamine Butylbromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination
Interventions: DRUG: Scopolamine Hydrobromide|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study to Evaluate the Long-Term Safety and Tolerability of MBX 2109 in Patients With Hypoparathyroidism
Status: NOT_YET_RECRUITING
Conditions: Hypoparathyroidism
Interventions: DRUG: 400 µg of MBX 2109 once-weekly by subcutaneous injection|DRUG: 200-1600 µg of MBX 2109 once-weekly by subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inetetamab Combined With Pyrotinib and Vinorelbine as First-line to Third-line Treatment for HER2-positive Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Inetetamab|DRUG: Pyrotinib|DRUG: Vinorelbine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Osteopathic Manipulative Therapy on Arrhythmias
Status: COMPLETED
Conditions: Cardiac Arrhythmia
Interventions: PROCEDURE: Osteopathic Manipulative Treatment|PROCEDURE: Light Touch Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Potential Effects of Trimethoprim on the Pharmacokinetics of ER OROS Paliperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ER OROS paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Immune Response and Safety Elicited by Henogen's Adjuvanted Hepatitis B Vaccine Compared to GSK Biologicals Adjuvanted Hepatitis B Vaccine in Pre-Dialysis and Dialysis Patients Who Have Not Been Exposed to Hepatitis B.
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Henogen HBV vaccine|BIOLOGICAL: FENDRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LUMINOS-101: Lerapolturev (PVSRIPO) and Pembrolizumab in Patients With Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|Supratentorial Glioblastoma|Brain Tumor
Interventions: BIOLOGICAL: lerapolturev|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Lung UltraSound Analysis (ILUSA) Study
Status: UNKNOWN
Conditions: COVID|Pregnancy Complications, Infectious|Pregnancy Related|Pregnancy, High Risk|Pregnancy Disease|Pneumonia|Pneumonia, Viral|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: standardized Lung Ultrasound (LUS) examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Ferric Carboxymaltose on Exercise Capacity After Kidney Transplantation
Status: COMPLETED
Conditions: Iron-deficiency|Transplant-Related Disorder
Interventions: DRUG: Ferric carboxymaltose|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Bluetooth enabled nebuliser device (I-neb)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study in the Treatment of Alcohol Dependence.
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: LY686017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Circadian Rhythm Sleep Disorder, Shift Work Type|Cholesterol Level, High
Interventions: DIETARY_SUPPLEMENT: grape seed proanthocyanidin extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gluten Intolerance in Patients With Diarrhea Predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Diarrhea|Diarrhea Predominant Irritable Bowel Syndrome
Interventions: OTHER: Gluten free diet|OTHER: Gluten rich diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Stability of Implants Placed in Partially Edentulous Maxilla With Poor Bone Quality Via New Reverse Drilling Technique Versus Osteotome Technique.
Status: UNKNOWN
Conditions: Dental Implant
Interventions: PROCEDURE: New Reverse Drilling technique|PROCEDURE: osteotome technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Laryngeal Ultrasound Useful in the Assessment for ILO? A Protocol for a Two-stage Exploratory Pilot Study
Status: RECRUITING
Conditions: Vocal Cord Dysfunction|Asthma Brittle|Inducible Laryngeal Obstruction|Paradoxical Vocal Fold Motion
Interventions: OTHER: Trans-cutaneous Laryngeal ultrasound (TLUS)|OTHER: TLUS and simultaneous laryngoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypofractionation With Simultaneous Integrated Boost vs. Standard Fractionation in Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Early-Stage Breast Carcinoma
Interventions: RADIATION: Standard Radiation|RADIATION: Hypofractionation with SIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulised Heparin in Patients With Severe COVID-19
Status: RECRUITING
Conditions: Covid19|Respiratory Failure
Interventions: DRUG: Nebulised unfractionated heparin (UFH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY
Status: COMPLETED
Conditions: Appetite and General Nutritional Disorders|Hormone Replacement
Interventions: DIETARY_SUPPLEMENT: lactisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CLINICAL PHASE III STUDY TO MONITOR THE SAFETY, TOLERABILITY AND EFFICACY OF SUBCUTANEOUS HUMAN IMMUNOGLOBULIN (OCTANORM) IN PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES, INCLUDING (BUT NOT LIMITED TO) THOSE WHO HAVE COMPLETED THE SCGAM-01 TRIAL
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: DRUG: Octanorm 16.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventative/Preemptive Adoptive Transfer of Peptide Stimulated CMV/EBV Specific T-cells in Patients After Allogeneic Stem Cell Transplantation
Status: COMPLETED
Conditions: Patients Undergoing Allogeneic Stem Cell Transplantation
Interventions: BIOLOGICAL: CMV/EBV specific T-cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of First Line Treatment of Chronic Graft Versus Host Disease With the Association of Ciclosporine, Corticosteroids and Rituximab (Protocol R-GVHD)
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: Rituximab|DRUG: Ciclosporine|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Labor Analgesia and Infant Neurobehavior
Status: COMPLETED
Conditions: Labor Pain
Interventions: DRUG: Ropivacaine and sufentanil|DRUG: Ropivacaine and sufentanil|DRUG: Ropivacaine and sufentanil|DRUG: Ropivacaine and sufentanil|DRUG: Ropivacaine and sufentanil|DRUG: Ropivacaine and sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of AMG 386 in Cancer Subjects With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Advanced Solid Tumors|Kidney Disease|Renal Impairment
Interventions: DRUG: AMG 386 + Paclitaxel|DRUG: AMG 386
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DRUG: Gepotidacin|DRUG: Placebo matching nitrofurantoin|DRUG: Nitrofurantoin|DRUG: Placebo matching gepotidacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: TissueGene-C|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Immune Ablation and CD34+ Peripheral Blood Stem Cell Support in Patients With Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: filgrastim|PROCEDURE: CD34+ Peripheral Blood Stem Cell Reinfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients
Status: COMPLETED
Conditions: Candidiasis, Esophageal|HIV Infections
Interventions: DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of High-Dose Rituximab in High-Risk Chronic Lymphocytic Leukemia Patients in Suboptimal Response After Induction Immunochemotherapy
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer
Status: UNKNOWN
Conditions: Castration-Resistant Prostatic Cancer|Metastatic Prostate Carcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer|Hormone-Refractory Prostate Cancer
Interventions: BIOLOGICAL: GnRH agonist/antagonist|DRUG: Prednisone|DRUG: Abiraterone Acetate|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Efficacy, Tolerability and Pharmacokinetics of LF111 (Drospirenone 4.0 mg) During 13 Cycles
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: LF111 (drospirenone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation For Cancer Smokers
Status: COMPLETED
Conditions: Cancer of Head and Neck|Breast Cancer|Prostate Cancer|Nicotine Dependence
Interventions: DEVICE: Transcranial Magnetic Stimulation Clinical Research System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma|Acute Lymphoblastic Leukemia|Follicular Lymphoma
Interventions: OTHER: tisagenlecleucel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adding L-Carnitine to Clomiphene Citrate for Induction of Ovulation in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Clomiphene Citrate 50mg|DRUG: L-carnitine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: flutamide|DRUG: triptorelin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An In-Hospital Family Member Cardiopulmonary Resuscitation (CPR) Education Program
Status: COMPLETED
Conditions: Cardiac Arrest|Coronary Disease|Cardiovascular Risk Factors
Interventions: OTHER: CPR Training using the Family and Friends CPR Anytime VSI Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of VM202 in Painful Diabetic Peripheral Neuropathy -The HOPES Trial
Status: UNKNOWN
Conditions: Painful Diabetic Neuropathy
Interventions: BIOLOGICAL: VM-202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A One-Week Crossover Dispensing Evaluation of New Daily Wear Soft Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Test Contact Lens|DEVICE: Nelfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Study on the Monthly Administration of 300 mg AliRocumab (PRALUENT®) With the 2 ml SYDNEY Auto-injector
Status: COMPLETED
Conditions: Primary Hypercholesterolaemia and Mixed Dyslipidaemia|Atherosclerotic Cardiovascular Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Systemic Bioavailability Study Of Col-118 Administered Topically as a 0.18 % Facial Gel And Brimonidine Ophthalmic Solution 0.2%
Status: COMPLETED
Conditions: Erythematous Rosacea
Interventions: DRUG: 0.18% COL-118 facial gel (1.8 mg brimonidine)|DRUG: 0.2% brimonidine ophthalmic solution (0.1 mg brimonidine tartrate/drop)|DRUG: Advanced Eye Relief|DRUG: COL-118 facial gel vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 RCT Study of CX-8998 for Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: CX-8998|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chinese Surgical Robot Clinical Study on Rectectomy for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DEVICE: Micro Hand S robot|DEVICE: Laparoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparasion of the Immediate Effect of Myofascial Relaxation Technique and Kinesiology Taping
Status: COMPLETED
Conditions: Diabetes Mellitus|Plantar Fascia
Interventions: OTHER: Kinesiology Taping Appliying|OTHER: Myofascial Release Technique Appliying
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Bupropion XL 150 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Abrika Bupropion 150 mg XL Tablet, single dose|DRUG: Wellbutrin XL® 150 mg Tablet, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Inhalational or Intravenous Anesthesia During Surgery for Patients With Colon Cancer, VIVA Study
Status: RECRUITING
Conditions: Colon Adenocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review|DRUG: Fentanyl Citrate|DRUG: Propofol|OTHER: Questionnaire Administration|DRUG: Sevoflurane|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Study Comparing Manual Treatment or Advice in Acute, Musculoskeletal Chest Pain
Status: COMPLETED
Conditions: Musculoskeletal Chest Pain|Non-cardiac Chest Pain|Undiagnosed Chest Pain
Interventions: PROCEDURE: chiropractic treatment|OTHER: Self-management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heparinization vs Salinization of the Peripheral Venous Catheter
Status: RECRUITING
Conditions: Catheter Complications
Interventions: DRUG: Low dose heparin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Ranibizumab to Treat Rubeosis in Diabetics Prior to Cataract Surgery
Status: COMPLETED
Conditions: Rubeosis Iridis|Proliferative Diabetic Retinopathy
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The WalkingTall Study: Comparing WalkingTall With Parkinson's Disease (WalkingTall-PD) With Mobility-plus to Reduce Falls and Improve Mobility.
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: WalkingTall-PD|OTHER: Mobility-plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Proton Beam Therapy to Treat Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Squamous Cell Carcinoma|Adenocarcinoma Of Esophagus
Interventions: RADIATION: Proton beam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haloperidol vs. Valproate in Agitation
Status: COMPLETED
Conditions: Psychomotor Agitation
Interventions: DRUG: Haloperidol|DRUG: Valproate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus a Sodium Picosulfate and Magnesium Salt Solution Using Day Before-Only Dosing Regimen in Adults.
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Carcinoma|Colon Cleansing
Interventions: DRUG: NER1006, Day Before-Only Dosing|DRUG: SP+MS, Day Before-Only Dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Aerobic Exercise in Obese Patients With Atherosclerotic Cardiovascular Disease
Status: NOT_YET_RECRUITING
Conditions: Obesity|Coronary Artery Disease
Interventions: OTHER: aerobic exercise on the treadmill+For both groups, patients will be recommended joint range of motion (ROM), stretching, strengthening, posture and balance and flexibility exercises for all joints.|OTHER: Walking at an intensity of 12-13 RPE+For both groups, patients will be recommended ROM, stretching, strengthening, posture and balance and flexibility exercises for all joints.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of OPC-61815 Injection Compared With Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: OPC-61815|DRUG: Tolvaptan Tab 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neratinib and Capmatinib Combination (Phase Ib/II) in Metastatic Breast Cancer and Inflammatory Breast Cancer Patients With Abnormal HER-family and c-Met Pathway Activity as Measured by the CELsignia Signaling Analysis Test
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Breast Cancer
Interventions: DRUG: Neratinib|DRUG: Capmatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biopsy Protocol of Upper Gastrointestinal Subepithelial Tumors:Diagnostic Accuracy of EUS-FNB Versus Unroofing Biopsy
Status: COMPLETED
Conditions: Upper Gastrointestinal Subepithelial Tumors
Interventions: PROCEDURE: unroofing biopsy|PROCEDURE: EUS-FNB(endoscopic ultrasonography guided fine needle biopsy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety and Tolerance of Regadenoson in Subjects With Asthma or Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Asthma|Coronary Artery Disease|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Regadenoson|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Efficacy and Safety of JMKX000623 in Participants With Diabetic Peripheral Neuropathic Pain
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: JMKX000623|DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin
Status: TERMINATED
Conditions: Pancreatic Neoplasm|Pituitary Neoplasm|Nelson Syndrome|Ectopic ACTH Syndrome
Interventions: DRUG: pasireotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blinded, Placebo Controlled, Single Dose Escalation Study of 608 in Healthy Subjects
Status: UNKNOWN
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: 608|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIOlogics in Severe Nasal POlyposis SurvEy
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Biologic treatments available in CRSwNP (dupilumab, mepolizumab and benralizumab according to their marketing approval)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas
Status: WITHDRAWN
Conditions: Astrocytoma|Brainstem Glioma|Ependymoma|Mixed Glioma|Oligodendroglioma|Optic Nerve Glioma
Interventions: RADIATION: Radiation therapy|DRUG: Temozolomide|PROCEDURE: Stem cell collection|PROCEDURE: Stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Casting vs Bracing for Idiopathic Early-Onset Scoliosis
Status: RECRUITING
Conditions: Scoliosis Idiopathic|Early-Onset Scoliosis Deformity of Spine
Interventions: PROCEDURE: Casting|DEVICE: Bracing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifiably Determine if the Botanical Formulation, LLP-01, Has a Significant Clinical Effect on Proteomic Inflammatory Biomarkers and Epigenetic Changes in Healthy, Older Individuals.
Status: COMPLETED
Conditions: Aging|Inflammation
Interventions: DIETARY_SUPPLEMENT: LLP-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: cetuximab|DRUG: Irinotecan|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Surgical Non-Small Cell Lung Cancer (NSCLC) Follow-up
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: PROCEDURE: Radiological Arm|PROCEDURE: Scannographic arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Immune Mechanisms in Atopic Eczema
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: PROCEDURE: Skin biopsy|PROCEDURE: Skin suction blister|BIOLOGICAL: Mantoux test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Iptacopan in Patients With ANCA Associated Vasculitis
Status: RECRUITING
Conditions: Anti-Neutrophil Cytoplasm Antibodies (ANCA) Associated Vasculitis
Interventions: DRUG: Iptacopan|DRUG: Placebo|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Seminal Fluid on the Colon Wall; Implications for HIV Transmission
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: BIOLOGICAL: Radiolabeled autologous seminal fluid|BIOLOGICAL: Radiolabeled Normosol-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Argipressin's Influence on Blood Loss During Hepatic Resection
Status: RECRUITING
Conditions: Colon Cancer Liver Metastasis|Inflammatory Response|Vasopressin Causing Adverse Effects in Therapeutic Use
Interventions: DRUG: Argipressin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Femtosecond Laser System VisuMax for Refractive Correction of Hyperopia by Means of Lenticule Extraction
Status: UNKNOWN
Conditions: Hyperopia
Interventions: PROCEDURE: Small incision lenticule extraction|DEVICE: ReLEx® (SMILE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Oxidative Stress and the Metabolic Pathology of Autism
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DIETARY_SUPPLEMENT: B12|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: folate|DIETARY_SUPPLEMENT: B complex|DIETARY_SUPPLEMENT: vitamin C|DIETARY_SUPPLEMENT: cod liver oil|DIETARY_SUPPLEMENT: Mineral complex|DIETARY_SUPPLEMENT: carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PU-H71 in Patients With Solid Tumors and Low-Grade Non-Hodgkin's Lymphoma That Have Not Responded to Standard Treatment
Status: TERMINATED
Conditions: Solid Tumors|Lymphoma
Interventions: DRUG: PU-H71
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Unilateral Versus Bilateral Approach to Robot-Assisted Rehabilitation in Patients With Subacute Stroke
Status: WITHDRAWN
Conditions: Subacute Stroke
Interventions: DEVICE: InMotion3 (IMT)|DEVICE: Bi-Manu-Track (BMT)|BEHAVIORAL: Control intervention (CI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-center Observational Study on the Progression of Atherosclerotic Plaques in Anti-PD-1 mAb Treated Tumor Patients by Artery Ultrasound Follow-up
Status: UNKNOWN
Conditions: Plaque, Atherosclerotic|Programmed Cell Death Protein 1 Inhibitor
Interventions: DRUG: PD-1 inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aim 3, Adapting and Implementing Evidence-based Breast Cancer Follow-up in Primary Care
Status: NOT_YET_RECRUITING
Conditions: Cancer, Breast|Health Care Utilization
Interventions: BEHAVIORAL: Practice Led Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) for TAK-906 in Participants With Diabetes Mellitus and Gastroparesis (DG) or With Idiopathic Gastroparesis (IG)
Status: COMPLETED
Conditions: Diabetes Mellitus and Gastroparesis, Idiopathic Gastroparesis
Interventions: DRUG: TAK-906 Maleate|DRUG: Metaclopramide|DRUG: TAK-906 Maleate Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Stratification of Blood Pressure Control Against Progress of Cerebral Small Vessel Diseases in Poststroke Patients
Status: UNKNOWN
Conditions: Cerebral Small Vessel Diseases
Interventions: DRUG: Azelnidipine|DRUG: Perindopril|DRUG: hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Minimally Invasive Procedures Used in Management of Salivary Ductal Pathologies on Patients' Symptomatology and Gland Function
Status: COMPLETED
Conditions: Salivary Gland Stone|Salivary Gland Diseases
Interventions: PROCEDURE: Minimally invasive techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dengue Vaccine in Healthy Toddlers Aged 12 to 15 Months in the Philippines
Status: COMPLETED
Conditions: Dengue Fever|Dengue Hemorrhagic Fever
Interventions: BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3 and 4 virus|BIOLOGICAL: OKAVAX®:Attenuated live varicella-zoster virus and AVAXIM® 80U: Hepatitis A virus Vaccines|BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3 and 4 virus and Childhood vaccines|BIOLOGICAL: Live, attenuated, recombinant dengue serotypes 1, 2, 3 and 4 virus and NaCl (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation of Visual Function After Bilateral Implantation of Two Presbyopia-Correcting Trifocal Intraocular Lenses (IOL)
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL|DEVICE: AT LISA® tri IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo|DRUG: Idalopirdine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Juice Consumption With Biofunctional Compounds and Probiotics on Subjective Appetite
Status: COMPLETED
Conditions: Subjective Appetite
Interventions: BEHAVIORAL: Orange juice with vitamin D3, n-3 fatty acids, and probiotics as preload
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of a Contraceptive Vaginal Ring Delivering Nestorone® and Ethinyl Estradiol
Status: COMPLETED
Conditions: Contraception
Interventions: COMBINATION_PRODUCT: NES/EE CVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IMB-guided Intervention to Encourage PrEP Uptake Among Young Men Who Have Sex With Men
Status: RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: IMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of TG-0054 With Single IV Doses Escalation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TG-0054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in Vestibular Schwannoma Surgery
Status: NOT_YET_RECRUITING
Conditions: Vestibular Schwannoma
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham-control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Placebo-Controlled Crossover Study for the Investigation of the Effect of Pantoprazole on Cardiac Contractility
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pantoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spatially and Temporally Resolving Predictive Biomarkers of Postoperative Recurrence and Complications in Chronic Intestinal Inflammation
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis|Crohn Disease
Interventions: PROCEDURE: CD patients|PROCEDURE: UC patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MESS-study MRSA Eradication Study Skåne
Status: COMPLETED
Conditions: Throatcarriers of MRSA
Interventions: DRUG: Mupirocin|DRUG: Rifampin+Clindamycine or Trimehoprimsulfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-paclitaxel and Gemcitabine Hydrochloride Followed by Radiation Therapy Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma|Resectable Pancreatic Carcinoma
Interventions: DRUG: Fluorouracil|DRUG: Gemcitabine|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Nab-paclitaxel|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AF Septal Pacing (Clinical Investigation Plan)
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fed Bioequivalence Study of Zolpidem Tartrate Tablets and Ambien® Tablets
Status: COMPLETED
Conditions: Healthy|Therapeutic Equivalency
Interventions: DRUG: Zolpidem Tartrate 10 mg tablet|DRUG: Zolpidem Tartrate 10 mg tablet (Ambien®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Mesothelioma, Malignant|Gene Abnormality|Pleural Mesothelioma
Interventions: GENETIC: PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Investigation Evaluating and Understanding Parameters Affecting the Performance of Ostomy Products
Status: COMPLETED
Conditions: Ileostomy - Stoma|Colostomy
Interventions: DEVICE: SenSura Mio Convex Soft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Retro-Auricular Single-Site Endoscopic to Papillary Thyroid Carcinoma
Status: RECRUITING
Conditions: Papillary Thyroid Carcinoma
Interventions: PROCEDURE: retro-auricular single-site endoscopic thyroidectomy|PROCEDURE: traditional open surgery thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Flow Restriction Method in Patellar Instability
Status: NOT_YET_RECRUITING
Conditions: Patellar Abnormality
Interventions: OTHER: Rehabilitation with blood blow restriction|OTHER: Rehabilitation without blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Long Term Plavix Therapy Post Angioplasty
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: plavix|DRUG: plavix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment for Augmenting Language in Children With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Behavioral Therapy|DRUG: Aripiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Twelve Week Study of Experimental Mouth Rinses
Status: COMPLETED
Conditions: Gingivitis|Plaque
Interventions: OTHER: Colgate Cavity Protection Toothpaste|OTHER: American Dental Association (ADA) Ref Toothbrush|OTHER: Prototype 1 Mouth Rinse|OTHER: Prototype 2 Mouth Rinse|OTHER: Prototype 3 Mouth Rinse|OTHER: Listerine Cool Mint Mouth Rinse|OTHER: Hydroalcohol Mouth Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Curcumin Supplementation in Cervical Cancer
Status: RECRUITING
Conditions: Locally Advanced Cervical Cancer
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Curcumin + Piperine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of a Treat-to-target (T2T) Disease Management Strategy vs. Routine Care (RC) in Adult Patients With Moderate to Severe Rheumatoid Arthritis (RA) Treated With Subcutaneous Abatacept (Orencia - SC)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Non-Interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
Status: COMPLETED
Conditions: Memory Disorder|Retention Disorder, Cognitive|Subjective Cognitive Impairment|Memory, Concentration or Attention Problems
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder
Status: COMPLETED
Conditions: Intermittent Explosive Disorder|Childhood Aggression|Oppositional Defiant Disorder|Attention Deficit Disorder
Interventions: BEHAVIORAL: Parent Management Training|OTHER: Placebo|DRUG: Intuniv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TQB3909 Tablets in Subjects With Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: 400mg of TQB3909 tablets|DRUG: 600mg of TQB3909 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Cancer Screening in a Population at High Risk
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Hereditary Diseases|Pancreatitis, Chronic
Interventions: PROCEDURE: endoscopic ultrasonography|PROCEDURE: magnetic resonance|DIAGNOSTIC_TEST: laboratory examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Trendelenburg Position for Acute Anterior Circulation Ischemic Stroke With Large Artery Atherosclerosis Etiology (HOPES 3)
Status: RECRUITING
Conditions: Stroke, Acute Ischemic
Interventions: OTHER: head-down position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Spinal Stabilization Exercises Focusing on the Pelvic Floor in Women With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: OTHER: Stabilization exercise+lifestyle recommendation|OTHER: lifestyle recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Dental Implant Placed in the Presence of Chronic Inflammatory Periapical Lesions
Status: COMPLETED
Conditions: Immediate Dental Implant|Tooth Exratction|Periapical; Infection
Interventions: PROCEDURE: Immediate dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MPER-656 Liposome Vaccine|BIOLOGICAL: Placebo for MPER-656 Liposome Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of CONAN® Proctological Cream for Treatment of Haemorrhoidal Disease
Status: COMPLETED
Conditions: Hemorrhoid Pain|Haemorrhoid Inflammation
Interventions: DEVICE: CONAN® Proctological Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 24-Wk β-Alanine Ingestion on Muscle Taurine and Clinical Blood Parameters in Healthy Males
Status: COMPLETED
Conditions: Sports Nutritional Physiological Phenomena
Interventions: DIETARY_SUPPLEMENT: Beta-alanine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of C19-IG 20% in SARS-CoV-2 Infected Asymptomatic Ambulatory Outpatients
Status: TERMINATED
Conditions: COVID-19|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection
Interventions: BIOLOGICAL: C19-IG 20%|DRUG: 0.9% Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetic of Melatonin Subsequent to the Consumption of Melatonin-rich Food Supplements
Status: COMPLETED
Conditions: Melatonin Bioavailability
Interventions: DIETARY_SUPPLEMENT: a prolonged release tablet and a spray containing melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ECOSPOR IV: An Open-Label Study Evaluating SER-109 in Recurrent Clostridioides Difficile Infection
Status: COMPLETED
Conditions: Clostridioides Difficile Infection
Interventions: BIOLOGICAL: SER-109
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome
Status: RECRUITING
Conditions: Sjögren's Syndrome
Interventions: DRUG: Deucravacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT