pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of HBV-001 D1 in Healthy Adults
Status: COMPLETED
Conditions: Dengue Fever
Interventions: BIOLOGICAL: DEN1-80E (HBV-001 D1 + 3.5 mg Alhydrogel)|BIOLOGICAL: Placebo for DEN1-80E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study of a Protocol to Treat Pediatric Oral Mucositis by Low-level Laser Therapy
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DEVICE: "Oncolase Digi" therapy laser diode
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Positron Emission Tomography (PET) Study Evaluating Brain Metabolism of a Medical Food in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: caprylidene|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Post- Thoracotomy Paravertebral Block
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antibody Drug Conjugate in Patients With Advanced Breast Cancer Expressing HER2
Status: COMPLETED
Conditions: Advanced Breast Cancer|Advanced Nonsmall Cell Lung Cancer|Advanced Gastric Cancer
Interventions: DRUG: XMT-1522
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EvaLuating negAtive pressUre Wound theRapy in brEast coNserving Surgery
Status: RECRUITING
Conditions: Breast Cancer|Seroma|Wound Complication
Interventions: DEVICE: Negative pressure wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon α-2b Injection for Hydroxyurea Resistant or Intolerant ET
Status: NOT_YET_RECRUITING
Conditions: Essential Thrombocythemia
Interventions: DRUG: Peginterferon α-2b injection|DRUG: Peginterferon α-2b injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Exercise Unit Versus Functional Electrical Stimulation On Genu Recurvatum In Diplegic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: universal exercis unit|DEVICE: functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Closed-loop Insulin Delivery System at Home With Tailored Home Care Services in Poorly Controlled Type 2 Diabetes Patients (T2D)
Status: COMPLETED
Conditions: Diabetes Type 2
Interventions: DEVICE: t:slim X2 with Control-IQ|OTHER: home healthcare services|OTHER: usual care for daily insulin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Short-term Steroid Therapy in Patients With P. Jirovecii Pneumonia Due to HIV / AIDS
Status: ENROLLING_BY_INVITATION
Conditions: Pneumocystis|HIV/AIDS|Steroid
Interventions: DRUG: Conventional steroid regimen|DRUG: Shortened steroid regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Peri-operative Use of Polymyxin-B Hemoperfusion in Septic Patients Undergoing Emergent Abdominal Surgery
Status: COMPLETED
Conditions: Abdominal Sepsis|Peritonitis|Colon Perforation
Interventions: OTHER: Polymyxin-B hemoperfusion|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ARTEMIS-PH - Study of Ambrisentan in Subjects With Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis|Pulmonary Hypertension
Interventions: DRUG: Ambrisentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Apatinib for Advanced Hepatocellular Carcinoma Patients After First-line Treatment Failure
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Apatinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial to Examine the Effect of Subcutaneous Exenatide (Bydureon®) on Glucose Control in Patients With Type I Diabetes
Status: COMPLETED
Conditions: Type I Diabetes
Interventions: DRUG: Exenatide (Bydureon®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Formulation of Sildenafil-loaded Nanocarriers for Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: sildenafil-loaded liposomes|DRUG: minoxidil gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Failure|End-Stage Kidney Disease
Interventions: DRUG: colon lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What Promotes Healthy Eating? The Roles of Information,Affordability,Accessibility,Gender, and Peers on Food Consumption
Status: COMPLETED
Conditions: Malnutrition|Stunted Growth|Growth|Feeding, Complementary
Interventions: BEHAVIORAL: Behavior change communication|OTHER: Food Voucher (Monetary)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Shoulder Muscle Activity During Isokinetic Evaluation of Rotators
Status: RECRUITING
Conditions: Muscle Activation|Electromyography|Muscle Strength|Shoulder
Interventions: OTHER: Isokinetic test + EMG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Intranasal Oxytocin and Learning in Autism
Status: WITHDRAWN
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Syntocinon (synthetic oxytocin)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on Sepsis-induced Intestinal Dysfunction
Status: UNKNOWN
Conditions: Sepsis|Intestinal Dysfunction
Interventions: DEVICE: electroacupuncture treatment|DEVICE: sham electroacupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing IntelliCare in Collaborative Care: A Quality Improvement Evaluation
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: IntelliCare|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acupuncture for Fatigue in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinsons Disease
Interventions: PROCEDURE: Acupuncture|OTHER: Acupuncture to treat fatigue in Parkinson disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2A Study of TRC253, an Androgen Receptor Antagonist, in Metastatic Castration-resistant Prostate Cancer Patients
Status: COMPLETED
Conditions: Metastatic Castrate-resistant Prostate Cancer|Adenocarcinoma, Prostate
Interventions: DRUG: TRC253
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of LY3154207 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3154207 Capsule|DRUG: LY3154207 Tablet|DRUG: Placebo|DRUG: Fluconazole Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allopurinol in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: allopurinol sustained-release capsules|DRUG: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-disciplinary HIV Integrated Mental Health Support Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus|HIV Infections
Interventions: BEHAVIORAL: CHIMES Intervention|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assistive Technology and Reduced Caregiver Burden
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia|Caregiver Burden|Quality of Life|Activities of Daily Living
Interventions: DEVICE: The MapHabit system|DEVICE: Dementia educational videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Therapeutic Effect of Computer-assisted Cognitive Function Training on Cognitive Dysphagia After Stroke
Status: WITHDRAWN
Conditions: Dysphagia|Cognitive Impairment|Stroke
Interventions: BEHAVIORAL: routine rehabilitation treatment|BEHAVIORAL: conventional cognitive training|BEHAVIORAL: Computer-assisted Cognitive Function Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: allogeneic natural killer cells|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early and Intensive Occupational Therapy in Mechanical Ventilated Patients
Status: UNKNOWN
Conditions: Critical Illness|Ventilator Lung|Impairment, Cognitive|Impairment, Coordination
Interventions: BEHAVIORAL: Early and Intensive Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery
Status: COMPLETED
Conditions: Dysentery, Shigella|Shigellosis|Diarrhea
Interventions: DRUG: Ciprofloxacin|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omeprazole on the Pharmacokinetics of SHR6390 in Healthy Subjects
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: SHR6390、Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fetal Treatment of Galenic Malformations
Status: RECRUITING
Conditions: Vein of Galen Malformations
Interventions: DEVICE: Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: IPH5401 and Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of the Appearance of Diabetic Ulcers in Patients With 3D Insole and LSCI.
Status: NOT_YET_RECRUITING
Conditions: Diabete Type 2|Diabetic Foot|Neuropathy, Diabetic|Vascular Disease, Peripheral|Diabetic Foot Ulcer
Interventions: DIAGNOSTIC_TEST: LSCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Educational and Supportive Counseling Program for Increasing Antiretroviral Use and Adherence in People With HIV
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Counseling sessions|BEHAVIORAL: Group workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BioDulse: The Effect of an Irish Seaweed Protein Extract on Glucose Control in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Seaweed protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurogenic Overactive Bladder Treatment on Parkinson's Disease Through Back Tibial Nerve Electrostimulation
Status: UNKNOWN
Conditions: Overactive Bladder|Parkinson Disease
Interventions: DEVICE: Back Tibial Nerve Electrostimulation|DEVICE: Placebo Electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neo-adjuvant Abiraterone + Luteinizing Hormone-Releasing Hormone (LHRH) Versus LHRH in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: LHRHa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation of Flicker Induced and Flow Mediated Vasodilatation in Patients With Endothelial Dysfunction and Healthy Volunteers.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Hypertension|Hypercholesterolemia|Regional Blood Flow
Interventions: PROCEDURE: Forearm blood flow measurement, Flow mediated dilation (FMD)|DEVICE: Zeiss Retinal Vessel Analyzer (RVA), Stimulation with Flicker-light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Deep Breathing Exercise and 4-7-8 Breathing Techniques on Anxiety and Quality of Life
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: OTHER: The deep breathing group|OTHER: 4-7-8 breathing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ARA290 in T2D (Effects of ARA 290, an Erythropoietin Analogue) in Prediabetes and Type 2 Diabetes)
Status: UNKNOWN
Conditions: Diabetes Type 2|Impaired Glucose Tolerance|Impaired Fasting Glucose
Interventions: DRUG: ARA 290
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation od Safety and Performance of the Omega™ LAA (Left Atrial Appendage) Occluder and Omega™ Delivery System in Patients With Non-Valvular Atrial Fibrillation and High Bleeding Risk
Status: RECRUITING
Conditions: Non-Valvular Atrial Fibrillation
Interventions: DEVICE: Omega™LAA Occluder implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults
Status: COMPLETED
Conditions: Hyperglycemia, Postprandial
Interventions: OTHER: Baobab fruit aqueous extract|OTHER: Placebo OGTT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Referral Decision-making for Advanced Treatment in Parkinson's Disease Through Objective Measurements and Patient Reported Outcomes.
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Neptune|OTHER: Standard clinical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensor-based Balance Training in Diabetes: A Virtual Reality Paradigm
Status: UNKNOWN
Conditions: Diabetes
Interventions: DEVICE: Sensor-based exercise training|OTHER: In-home balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Montelukast in Asthmatic Children With and Without Food Allergy
Status: COMPLETED
Conditions: Bronchial Asthma|Food Allergy|Children
Interventions: DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macrobiotic Diet and Flax Seed: Effects on Estrogens, Phytoestrogens, & Fibrinolytic Factors
Status: COMPLETED
Conditions: Cardiovascular Diseases|Osteoporosis|Breast Cancer|Endometrial Cancer
Interventions: BEHAVIORAL: American Heart Association Step 1 diet|BEHAVIORAL: American Heart Association Step 2 diet + 10 g/day flax seed|BEHAVIORAL: Macrobiotic dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: IPACK on Early Pain Scores After ACL Reconstruction
Status: RECRUITING
Conditions: Pain, Postoperative|Anterior Cruciate Ligament Injuries|Analgesics, Opioid
Interventions: DRUG: IPACK|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Butorphanol in Pain Following Ablation for Hepatic Tumor
Status: COMPLETED
Conditions: Visceral Pain|Microwave Ablation|Hepatic Tumor
Interventions: DRUG: Butorphanol|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy for Infertile PCOS Patients Ovulating Under Clomiphene Citrate or Metformin
Status: WITHDRAWN
Conditions: Polycystic Ovary Syndrome|Infertility
Interventions: DRUG: Clomiphene citrate, metformin, highly purified urinary FSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Hemoglobin Induction Treatment Metformin
Status: COMPLETED
Conditions: Sickle Cell Anemia|Sickle Cell Disease|Hemoglobin Disorder
Interventions: DRUG: Metformin|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of IG-001 Versus Nab-paclitaxel in Metastatic or Locally Recurrent Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Locally Recurrent Breast Cancer
Interventions: DRUG: Nab-paclitaxel|DRUG: IG-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viveve Geneveve Treatment of the Vaginal Introitus to Evaluate Safety and Efficacy
Status: COMPLETED
Conditions: Female Sexual Dysfunction
Interventions: DEVICE: Geneveve Treatment|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Renal Artery Ablation in Resistant Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: St. Jude Medical renal artery ablation system: RF ablation generator (IBI 1500T11.5) and Renal artery ablation catheter (DS3D001, DS3D002)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PCI With AXXESS Biolimus A9 Eluting Bifurcation Stent in Treating Coronary Artery Bifurcation Disease
Status: WITHDRAWN
Conditions: Coronary Bifurcation Lesions
Interventions: DEVICE: OCT-guided PCI with AXXESS stent|DEVICE: OCT-guided PCI with conventional DES (Biomatrix flex stent)|DEVICE: Angio-guided PCI with AXXESS stent|DEVICE: Angio-guided PCI with PCI with conventional DES (Biomatrix flex stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic Ulcer
Status: UNKNOWN
Conditions: Peptic Ulcer
Interventions: DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of GSMs-TACE Combined With Surgical Resection in Treatment of Huge Hepatocellular Carcinoma (HCC) (≥10cm)
Status: UNKNOWN
Conditions: Huge Hepatocellular Carcinoma (HCC) (≥10cm)
Interventions: DEVICE: GSMs-TACE|PROCEDURE: Surgical Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Effectiveness of an Investigational Vaccine in Infants (V419-002)
Status: COMPLETED
Conditions: Bacterial Infections; Virus Diseases
Interventions: BIOLOGICAL: AR51 (12, 10)|BIOLOGICAL: PR51 (3, 10)|BIOLOGICAL: PR51 (6, 10)|BIOLOGICAL: PR51 (6, 15)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Valcyte (Valganciclovir) CMV Prophylaxis After Renal Transplantation
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: Valganciclovir CMV Prophylaxis|DRUG: Valganciclovir (Pre-emptive CMV Therapy)|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide in Subjects With intermediate2 or High MDS Associated With a Deletion (DEL) 5q [31]
Status: UNKNOWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: LENALIDOMIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weaning of Norepinephrine Guided by the Dynamic Arterial Compliance in Cardiac Surgery Post Operative.
Status: COMPLETED
Conditions: Vasoplegic Syndrome
Interventions: DRUG: Norepinephrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hydrocodone Bitartrate (HYD) in Subjects With Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DRUG: Hydrocodone bitartrate q24h film-coated tablets|DRUG: Placebo to match hydrocodone bitartrate q24h tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Honeycomb Microporous Covered Stents (NCVC-CS1) for the Treatment of Intracranial Aneurysms
Status: COMPLETED
Conditions: Intracranial Aneurysm
Interventions: DEVICE: NCVC-CS1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Antipsychotic-associated Obesity With a GLP-1 Analogue
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome X|Drug-induced Obesity|Schizophrenia
Interventions: DRUG: Exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Docetaxel, nedaplatin, fluorouracil|DRUG: Docetaxel, cisplatin, fluorouracil|DRUG: Nedaplatin|DRUG: Cisplatin|RADIATION: Intensity modulated-radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Bioequivalence of Sumatriptan Delivered Via the Intraject System
Status: COMPLETED
Conditions: Pharmacokinetics|Bioequivalence
Interventions: DEVICE: Sumatriptan (via Intraject System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of 18F-Thretide PET/CT in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: A single dose of 7±1 mCi (259±37 MBq) IV injection of 18F-Thretide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Computed tomography angiography (cardiac CT)|PROCEDURE: Invasive coronary angiography (ICA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Knee Articular Cartilage Repair: Cartilage Autograft Implantation System Versus Conventional Microfracture
Status: UNKNOWN
Conditions: Other Articular Cartilage Disorders|Osteochondritis Dissecans
Interventions: PROCEDURE: Microfracture|DEVICE: Cartilage Autograft Implantation System (CAIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan (DS-8201a)|DRUG: Capecitabine|DRUG: Eribulin|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: SEP-363856|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: OTHER: 18-F Florbetapir PET/MR scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor
Status: NOT_YET_RECRUITING
Conditions: GVHD
Interventions: DRUG: Grafalon|DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cryobiopsy for Suspected Malignant Peripheral Lymphadenopathy
Status: NOT_YET_RECRUITING
Conditions: Cryobiopsy of Peripheral Lymph Nodes
Interventions: PROCEDURE: Cryobiopsy|DEVICE: Cryobiopsy|PROCEDURE: Core Needle Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of JNJ-26113100 in the Treatment of Adult Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: JNJ-26113100 (50 mg) once daily|DRUG: JNJ-26113100 (100 mg) once daily|DRUG: JNJ-26113100 (100 mg) twice daily|DRUG: JNJ-26113100 (250 mg) twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study for Treatment of Alopecia Areata Using Carboxytherapy and Intralesional Steroids
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: DEVICE: Carboxytherapy|DRUG: Intralesional Steroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: Sirolimus (Rapamune)|DRUG: Cyclosporin (Neoral) or Tacrolimus (Prograf)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Brimonidine Tartrate Ophthalmic Solution, 0.15% in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brimonidine Tartrate Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Gelsemium Sempervirens in Anticipatory Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Gelsemium Sempervirens|DRUG: Gelsemium Sempervirens|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dry Needling and Prolotherapy on Pain, Function, and Quality of Life in Patients With Cervical Radiculopathy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Radiculopathy
Interventions: DIAGNOSTIC_TEST: conventional treatment with Prolotherapy|OTHER: Dry Needling and conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bevacizumab Versus Ranibizumab for the Treatment of Diabetic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Retinopathy|Macular Edema
Interventions: DRUG: Bevacizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Localized High-Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate|Stage III Prostate Cancer
Interventions: RADIATION: stereotactic body radiation therapy|OTHER: quality-of-life assessment|OTHER: laboratory biomarker analysis|DRUG: androgen deprivation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide + Plerixafor in Previously Treated Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Lenalidomide + Plerixafor (+ Rituximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Two Fissure Sealants
Status: UNKNOWN
Conditions: Caries Pit and Fissure Limited to Enamel
Interventions: DEVICE: fissure sealing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does Wrapping With Bone Marrow Injection Enhance Healing of Meniscal Sutures Into the Avascular Area
Status: RECRUITING
Conditions: Meniscus Lesion
Interventions: PROCEDURE: suturing meniscal augmented|PROCEDURE: suturing meniscal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of 2 Different Serving Regimens of Theobromine on Physiological Effects
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Theobromine|DIETARY_SUPPLEMENT: Theobromine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Integrated Mental Health Care and Vocational Rehabilitation to People With to Common Mental Disorders
Status: COMPLETED
Conditions: Common Mental Disorders|Depression|Anxiety|Personality Disorders|Functional Disease Present|Stress
Interventions: BEHAVIORAL: IBBIS II|BEHAVIORAL: Service as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Type 2 Diabetes|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Walnuts|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Craniosacral Test and Primitive Reflexes in Infant Neurodevelopment
Status: COMPLETED
Conditions: Child Development Disorder
Interventions: DIAGNOSTIC_TEST: Series of questions to parents of children in a virtual form.|OTHER: Intervention by teachers|PROCEDURE: Physiotherapeutic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Yoga Practice on Pain Intensity, Menstruation Symptoms and Quality of Life in Primary Dysmenorrhea
Status: COMPLETED
Conditions: Primary Dysmenorrhea|Pain, Menstrual|Quality of Life
Interventions: OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Muscle-Sparing Effect Of Human Chorionic Gonadotropin (hCG) During a Very Low Calorie Diet (VLCD)
Status: COMPLETED
Conditions: HCG
Interventions: DRUG: Human Chorionic Gonadotropin|DRUG: Placebo|OTHER: Low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lowering Stress Levels of Women in Lebanon
Status: COMPLETED
Conditions: Stress|Resilience|Self Efficacy|Happiness
Interventions: BEHAVIORAL: Transcendental Meditation (TM) practice|OTHER: Stress reduction class (online)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smoking Reduction Intervention for Smokers Not Willing to Quit Smoking: a Randomised Control Trial
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: PROCEDURE: Reduction Intervention + Adherence Intervention|BEHAVIORAL: Reduction Intervention|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose:
Clinical trial: The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DIAGNOSTIC_TEST: Complete blood picture (done in the morning after the night of monitored sleep by PSG. With stress on red blood cell indices (RBC count, MCV, MCH, RDW)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiarrhythmic and Cardioprotective Effects of Atorvastatin Versus Magnesium Sulfate in Cardiac Valve Replacement Surgery
Status: UNKNOWN
Conditions: Arrhythmias
Interventions: DRUG: Atorvastatin|DRUG: Magnesium Sulfate|OTHER: intravenous placebo|OTHER: tablets placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Plasma Concentrations, Metabolism and Excretion of 14C-paliperidone After a Single Oral Dose
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: 14C-paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Carotid Artery Stenosis and Lower Limb Peripheral Ischemia Prior to CABG
Status: COMPLETED
Conditions: Carotid Artery Diseases|Peripheral Artery Disease
Interventions: DIAGNOSTIC_TEST: carotid duplex, both LL arterial duplex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Southern Bone & Joint Study - Brimless Sockets
Status: COMPLETED
Conditions: Socket Designs of Transfemoral Amputees.
Interventions: DEVICE: Standard of care socket|DEVICE: Prosthetic brimless socket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation Frequency Study
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: Sham|DEVICE: 1200 Hz|DEVICE: 3030 Hz|DEVICE: 5882 Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Postmarket Randomized Study of the Treatment of Superficial Partial-Thickness Burns Using Two Dressings
Status: TERMINATED
Conditions: Burns
Interventions: DEVICE: AWBAT Wound Dressing|DEVICE: AWBAT™, Biobrane®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Budesonide Orodispersible Tablet vs. Placebo in Active Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Budesonide 1mg orodispersible tablet twice daily|DRUG: Placebo orodispersible tablet twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non Invasive Ventilation Versus Continuous Positive Airway Pressure After Extubation of Very Low Birth Weight Infants.
Status: UNKNOWN
Conditions: Neonatal Respiratory Failure
Interventions: PROCEDURE: CPAP ventilation mode|PROCEDURE: NIPPV ventilation mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Combined With rAd-p53 Gene in Treatment Advanced Non-small-cell Carcinoma
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Surgery combined with rAd-p53 gene therapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remediation of Visual Perceptual Impairments in People With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: UltimEyes|BEHAVIORAL: Contour Integration Training|BEHAVIORAL: UltimEyes + Contour Integration Training|BEHAVIORAL: MyBrainSolutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3872386 in Healthy Participants and Participants With Atopic Dermatitis
Status: TERMINATED
Conditions: Healthy|Atopic Dermatitis
Interventions: DRUG: LY3872386|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PETHEMA-BLIN-01/PET069014 (BLIN-01)
Status: TERMINATED
Conditions: Philadelphia Chromosome-negative or BCR-ABL-negative, CD19-positive ALL
Interventions: DRUG: blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Aerobics and Pilates Exercises in Primigraivda Females
Status: COMPLETED
Conditions: Depression|Sleep Quality|Primigravida Females
Interventions: OTHER: Aerobic exercises|OTHER: Pilates exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DEVICE: intermittent theta burst stimulation|DRUG: intravenous citalopram hydrochloride (CIT)|DEVICE: continuous theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis
Status: UNKNOWN
Conditions: Demodicidosis|Rosacea
Interventions: DRUG: ivermectin cream 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of the Performance and Placement Test for Predicting Supraglottic Airway Device (SAD) Position in the Hypopharynx as Confirmed With Video Laryngoscopy
Status: UNKNOWN
Conditions: General Anesthesia|Supraglottic Airway Device|Laryngeal Mask Airway
Interventions: DEVICE: Video-laryngoscopy following SAD insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)
Status: COMPLETED
Conditions: Uterine Cervix Cancer
Interventions: DRUG: Nelfinavir|BIOLOGICAL: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Delivery Route on PK of Sufentanil NanoTab
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Treatment A: Sufentanil IV|DRUG: Treatment B: Sufentanil NanoTab Sublingual|DRUG: Treatment C: Sufentanil NanoTab Buccal|DRUG: Treatment D: Sufentanil NanoTab Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Novel Sodium Bicarbonate Ingestion of Buffering Capacity
Status: COMPLETED
Conditions: PERFORMANCE-ENHANCING EFFECT
Interventions: DIETARY_SUPPLEMENT: Modified Sodium Bicarbonate|DIETARY_SUPPLEMENT: Acute Sodium Bicarbonate|DIETARY_SUPPLEMENT: Calcium carbonate (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fixation of the Posterior Malleolus in Medium-sized Trimalleolar AO Weber-B Fractures.
Status: UNKNOWN
Conditions: Trimalleolar Fracture|Posterior Malleolus|Open Reduction and Internal Fixation
Interventions: DEVICE: Fixation|OTHER: NO Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic, Safety, Tolerability and Immunogenicity Study of Adalimumab in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: BIOLOGICAL: TUR01|BIOLOGICAL: Adalimumab-EU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Hoya Surgical Optics (HSO) iSert 251 Posterior Chamber Aspheric Aphakic Intraocular Lens to Historical / Literature Controls.
Status: COMPLETED
Conditions: Aphakia|Cataract
Interventions: DEVICE: iSert 251 intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study Evaluating AMG 232 Alone and in Combination With Trametinib in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Advanced Malignancy|Cancer|Oncology|Oncology Patients|Acute Myeloid Leukemia
Interventions: DRUG: AMG 232|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-administered ONe-of-a Kind Approach to Epilepsy Therapy Through a Web-based Music Application
Status: NOT_YET_RECRUITING
Conditions: Epilepsy|Refractory Epilepsy|Music
Interventions: OTHER: Experimental Intervention (Music A)|OTHER: Active Comparator Intervention (Music B)|OTHER: Active Comparator Intervention (Music C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE