pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Evaluation of Self- Adhesive Bulk-fill Resin Composite Versus Conventionally Bonded Bulk-fill Resin Composite in Restoration of Proximal Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries Class II
Interventions: PROCEDURE: Class II Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preimplantation Genetic Screening (PGS) in Advanced Female Age and Male Severe Factor
Status: COMPLETED
Conditions: Embryo Aneuploidies|Implantation Rates|Infertility
Interventions: GENETIC: PGS|GENETIC: PGS|OTHER: Prolonged culture|OTHER: Prolonged culture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Clevidipine on Intracranial Pressure and Cerebral Perfusion Pressure (CCP) in Brain Injured Patients
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: clevidipine butyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Epigenetic Priming Using Decitabine With Induction Chemotherapy in AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesphere for Autonomic Alteration
Status: WITHDRAWN
Conditions: Hart Failure With Reduced Ejection Fraction
Interventions: DEVICE: EMF|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fractional CO2 Laser as a Mono- or Adjuvant Therapy for Alopecia Areata
Status: UNKNOWN
Conditions: Alopecia Areata
Interventions: DEVICE: fractional carbon dioxide laser alone|DRUG: Triamcinolone Acetonide 10mg/mL|BIOLOGICAL: platelet rich plasma|DRUG: vitamin D solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of rhBNP in Pediatrics After Corrective Repair of Tetralogy Of Fallot
Status: COMPLETED
Conditions: Congenital Heart Defects|Tetralogy Of Fallot
Interventions: DRUG: recombinant human brain natriuretic peptide (rhBNP)|DRUG: Placebo (0.9% sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apomorphine in Parkinson's Disease Patients With Visual Hallucinations
Status: UNKNOWN
Conditions: Parkinson's Disease|Hallucinations, Visual
Interventions: DRUG: Apomorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Negative Wound Pressure Therapy (PICO-7) Following Groin Incisions in Vascular Surgery (PICO-Vasc Study)
Status: RECRUITING
Conditions: Surgical Wound Infection
Interventions: OTHER: Regular waterproof sterile dressing.|OTHER: Prophylactic Negative Pressure Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Omega-3 Fatty Acids for Treatment of Depression in Adolescents
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Fish Oil|BEHAVIORAL: Cognitive Behavior Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Celiac Safe Food Additive
Status: COMPLETED
Conditions: Gluten Intolerance
Interventions: OTHER: Breakfast rolls consisting of wheat flour with and without a E304i/zinc additive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of TG103 Injection in Non-diabetic Overweight or Obesity
Status: NOT_YET_RECRUITING
Conditions: Overweight or Obesity
Interventions: DRUG: TG103 22.5 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study to Assess the Effect of Long-Term Prolonged-Release Fampridine (BIIB041) on Quality of Life as Reported by Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Fampridine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death Protein 1 (PD1) Blockade
Status: COMPLETED
Conditions: Advanced or Unresectable Melanoma Progressing After PD1 Blockade
Interventions: BIOLOGICAL: ONCOS-102|DRUG: Cyclophosphamide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Trial of Neoadjuvant Sintilimab and Chemotherapy for NSCLC Harboring No Driver Mutations
Status: RECRUITING
Conditions: NSCLC, Stage IIIA|EGF-R Negative Non-Small Cell Lung Cancer|ALK Negative NSCLC
Interventions: DRUG: PD-1 and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of SID142 in Patients With Chronic Artery Occlusive Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: SID142|DRUG: Rinexin® Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dual-mode ER:YAG Laser in Patients With Long Keloid/Hypertrophic Scars
Status: WITHDRAWN
Conditions: Keloid|Hypertrophic Scars
Interventions: DEVICE: Laser coagulation|DEVICE: Laser w/o coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgery and Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer That Can Be Removed During Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Nonsurgical Periodontal Treatment Associated or Not With Systemic Antibiotics and Photodynamic Therapy
Status: COMPLETED
Conditions: Aggressive Periodontitis, Generalized
Interventions: PROCEDURE: periodontal debridement|PROCEDURE: photodynamic therapy|DRUG: systemic clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liberal Versus Goal-directed Intraoperative Fluid Therapy in Pediatric Patients
Status: UNKNOWN
Conditions: Adverse Anesthesia Outcome
Interventions: DRUG: conventional liberal fluid regimen|DRUG: restricted fluid regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Efficacy of IONIS-AGT-LRx, an Antisense Inhibitor Administered Subcutaneously to Hypertensive Participants With Controlled Blood Pressure
Status: COMPLETED
Conditions: Mild Hypertension
Interventions: DRUG: Placebo|DRUG: ISIS 757456
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Handheld vs Traditional Ultrasound
Status: COMPLETED
Conditions: Image, Body
Interventions: DEVICE: Portable, handheld point-of-care ultrasound device|DEVICE: Cart-based point-of-care ultrasound device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dietary Maneuvers to Reduce Production of Colon-Derived Uremic Solutes
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DIETARY_SUPPLEMENT: Fiber|DIETARY_SUPPLEMENT: Corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Regular vs Intermittent Dose Ibuprofen for the Treatment of Ankle Sprains in Children
Status: COMPLETED
Conditions: Ibuprofen|Ankle Injuries
Interventions: DRUG: Ibuprofen Regular Dosing|DRUG: PRN dosing Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observation and Mechanism Study of Yunnan Baiyao in Different Stages of Diabetic Foot
Status: RECRUITING
Conditions: Diabetic Foot|Therapeutics
Interventions: DRUG: Yunnan Baiyao
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Lenalidomide and Autologous Mature Dendritic Cells Pulsed With KRN7000 in Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: DRUG: Lenalidomide|BIOLOGICAL: Monocyte derived DCs loaded with KRN7000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Topical Sesame Oil Versus Topical Triamcinolone on Oral Lichen Planus and Salivary Level of Oxidative Stress Biomarker [MDA]
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Sesame Oil|DRUG: triamcinolone in orabase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Study of ME1100 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ME1100 inhalation solution|DRUG: ME1100 placebo inhalation solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Addition of an Anti-cancer Drug, Lenalidomide, to the Usual Combination Chemotherapy Treatment ("EPOCH") for Adult T-Cell Leukemia-Lymphoma (ATL)
Status: RECRUITING
Conditions: Acute Adult T-Cell Leukemia/Lymphoma|Adult T-Cell Leukemia/Lymphoma|Chronic Adult T-Cell Leukemia/Lymphoma|HTLV-1 Infection
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Lenalidomide|PROCEDURE: Positron Emission Tomography|DRUG: Prednisone|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Cisplatin in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: cisplatin|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Liposomal Amikacin for Inhalation in Cystic Fibrosis (CF) Patients With Chronic Pseudomonas Aeruginosa (Pa) Infection
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Liposomal amikacin for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: pregabalin|DRUG: placebo|DRUG: pramipexole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: polifeprosan 20 with carmustine implant|PROCEDURE: surgical procedure|RADIATION: iodine I 125
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics ATG-F4 in Cancer Patients
Status: RECRUITING
Conditions: Pancreatic Cancer|Colon Cancer
Interventions: DRUG: LT-002 (Lactobacillus reuteri ATG-F4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Additional Effects of Kinesiotape and Neuromuscular Electrical Stimulation on the Hand Activity.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Experimental: KTT group|OTHER: Active Comparator: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Frequence of Dressing Change and Bacterial Colonization in Pediatric Intensive Care Unit
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: OTHER: 24hrs dressings change|OTHER: 7days dressings change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Testosterone Replacement Therapy for the Improvement of Post-Operative Outcomes in Patients With Low Testosterone
Status: RECRUITING
Conditions: Hypogonadism|Malignant Urinary System Neoplasm|Urinary System Disorder|Urinary System Neoplasm
Interventions: OTHER: Best Practice|PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Testosterone Cypionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Induction Chemoimmunotherapy Combined With Chemoradiotherapy in Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer|Immunotherapy|Induction Therapy|Chemoradiotherapy|Surgery
Interventions: DRUG: Cardonilizumab|RADIATION: Chemoradiotherapy ±immunotherapy|PROCEDURE: Radical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovations in Clinical Care of CE Approved Nucleus Cochlear Implant Recipients
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Cochlear Implant and sound processor device fitting paradigm or diagnostic/measurement technique|DEVICE: Standard of care fitting or diagnostic measurement of Cochlear Implant and sound processor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Pharmacokinetic Study of an Experimental Paracetamol Formulation
Status: COMPLETED
Conditions: Headache, Tension-Type
Interventions: DRUG: Experimental paracetamol|DRUG: Paracetamol marketed formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Litramine in 1 Year Weight Loss Study
Status: COMPLETED
Conditions: Obesity; Excess Calories|Overweight and Obesity|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Litramine|DIETARY_SUPPLEMENT: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Signature, Falls Risk, and Home-Based Interventions in Older Adults With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Fall
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Xerostomia|Head and Neck Neoplasms
Interventions: DEVICE: Active Electrostimulator device|DEVICE: Sham Electrostimulator device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Booster Feedback After Alcohol Health Education
Status: COMPLETED
Conditions: College Student Drinking
Interventions: BEHAVIORAL: e-checkup to go|BEHAVIORAL: Feedback-only booster|BEHAVIORAL: Feedback-plus-personal-contact booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of the Internet-delivered Treatment "One Step at the Time" for Bodily Distress Syndrome
Status: WITHDRAWN
Conditions: Bodily Distress Disorder Moderate|Fibromyalgia|Chronic Fatigue Syndrome|Irritable Bowel Syndrome|Somatization Disorder
Interventions: BEHAVIORAL: Internet-delivered treatment: "One step at the time"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absence of Steroid in Renal Transplantation and Digital Fibrosis Observation
Status: COMPLETED
Conditions: Renal Transplant
Interventions: OTHER: Absence of corticotherapy post-transplantation|DRUG: Corticotherapy post-transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of LACTOFOS in Constipated Patients
Status: UNKNOWN
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Symbiotic Lactofos|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inhibition of Lipid Peroxidation During Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass Induced Lipid Peroxidation
Interventions: DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance of a Derivative of Salicylic Acid and 5% Benzoyl Peroxide in Facial Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Lipo Hydroxy Acid|DRUG: 5% benzoyl peroxide gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Viaskin Peanut in Peanut-allergic Children 4-7 Years of Age
Status: RECRUITING
Conditions: Allergy, Peanut
Interventions: DRUG: DBV712|OTHER: Placebo|DRUG: DBV712
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vidatalk Communication Application: Usability, Acceptability and Efficacy Study
Status: COMPLETED
Conditions: Nonverbal Communication|Critical Illness
Interventions: OTHER: Aim 1 - VidaTalk - post-extubation|OTHER: Aim 2 - VidaTalk - intubated|DEVICE: Aim 3 - VidaTalk tablet app|OTHER: Aim 3 - attention-control with non-VidaTalk tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Study to Assess AER-271
Status: COMPLETED
Conditions: Stroke|Stroke, Acute|Stroke, Ischemic
Interventions: DRUG: AER-271|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Underlying Mechanisms For S. Aureus Infection And Colonization Of Skin in People With Atopic Dermatitis With And Without Eczema Herpeticum (MRSA)
Status: COMPLETED
Conditions: Methicillin-Resistant Staphylococcus Aureus|Atopic Dermatitis|Eczema Herpeticum|MRSA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FX-322 in Adults With Acquired Sensorineural Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural|Noise Induced Hearing Loss|Sudden Hearing Loss
Interventions: DRUG: FX-322|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sodium Polystyrene Sulfonate in the Treatment of Hyperkaliemia in Pre-dialysis Patients
Status: COMPLETED
Conditions: Hyperkalemia|Chronic Kidney Failure
Interventions: DRUG: Sodium polystyrene sulfonate|DRUG: Lactose with carob gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Different Formulations of an Adjuvanted A/H1N1 Pandemic Vaccine in Healthy Adults and the Elderly
Status: COMPLETED
Conditions: Influenza|Swine-origin A/H1N1 Influenza
Interventions: BIOLOGICAL: Monovalent Subvirion A/H1N1 influenza vaccine with adjuvant|BIOLOGICAL: Monovalent Subvirion A/H1N1 influenza vaccine with adjuvant|BIOLOGICAL: Monovalent Subvirion A/H1N1 influenza vaccine|BIOLOGICAL: Monovalent Subvirion A/H1N1 influenza vaccine|BIOLOGICAL: Normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Preoperative Treatment of HR+/HER2+Breast Cancer With Pirotinib, Trastuzumab and AI Research
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pyrrolidine、trastuzumab、AI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation Guided by Ablation Index (Ablation Index Registry Study)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: PVI using ThermoCool® SmartTouch® Catheter|DEVICE: PVI using ThermoCool® SmartTouch SF® Catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vitamin and mineral supplement|DRUG: Vitamin and mineral supplement|DRUG: Placebo|DRUG: 100% Oxygen|DRUG: Escherichia coli Endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Escalation of Doses of Daratumumab in Combination With Chemotherapy (Idarubicin and Cytarabine) in Patients of 60 Years Old or More With Adverse Risk Acute Myeloblastic Leukemia (AML) (DARALAM)
Status: NOT_YET_RECRUITING
Conditions: Adult Patients With Adverse Risk Acute Myeloblastic Leukemia
Interventions: DRUG: Darzalex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cardiac Rehabilitation (CR) on Functional Capacity and Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Cardiovascular Disease|Coronary Disease
Interventions: BEHAVIORAL: comprehensive CR|OTHER: exercise-based CR|OTHER: wait list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femtosecond Laser Assisted Keratoplasty
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Femtosecond laser assisted keratoplasty|PROCEDURE: PKP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise Training on the Function of the High Density Lipoprotein (HDL)-Cholesterol, Endothelial Function and Endothelial Progenitor Cells in Patients With Metabolic Syndrome(HERMET-Study)
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: BEHAVIORAL: physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification
Status: COMPLETED
Conditions: Cystoid Macular Edema|Cataract
Interventions: DRUG: Nepafenac|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Clinical Efficacy and Acceptability of Think Positive (T+) in Diabetes Management
Status: COMPLETED
Conditions: Diabetes (Insulin-requiring, Type 1 or Type 2)
Interventions: DEVICE: Mobile phone telehealth application: Think Positive (T+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine
Status: RECRUITING
Conditions: Migraine Without Aura|Migraine With Aura
Interventions: DRUG: Anisodine Hydrobromide|DRUG: Anisodine Hydrobromide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Corticosteroid and Topical Steroids in the DRESS
Status: UNKNOWN
Conditions: Drug Rash With Eosinophilia and Systemic Symptoms
Interventions: DRUG: Prednisone|DRUG: Clobetasol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials
Status: RECRUITING
Conditions: Spinal Muscular Atrophy (SMA)
Interventions: BIOLOGICAL: onasemnogene abeparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health of Peri-implant Tissues Adjacent to Zirconia
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: DEVICE: Glazing|DEVICE: Polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Long-term Effects Secondary to Cancer Therapy in Children|Neurotoxicity|Psychosocial Effects of Cancer and Its Treatment
Interventions: PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Tarragon on Insulin Action in Humans
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: An alcoholic extract of Artemisia dracunculus L.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Treprostinil Diethanolamine Manufactured by Two Independent Facilities
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil diethanolamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy With Docetaxel, Capecitabine and Cisplatin in Patients With Advanced Gastric Cancer: Adjuvant DXP
Status: COMPLETED
Conditions: Resected Advanced Gastric Cancer
Interventions: DRUG: docetaxel, capecitabine, cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Mechanisms of Psychosocial Chronic Pain Treatments
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: BEHAVIORAL: cognitive therapy|BEHAVIORAL: mindfulness training|BEHAVIORAL: behavioral therapy|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Treatment Modalities for Lower Pole and Renal Pelvis Stones
Status: SUSPENDED
Conditions: Kidney Stones
Interventions: PROCEDURE: Endoscopic kidney stone surgery|PROCEDURE: Endoscopic kidney stone surgery|PROCEDURE: Endoscopic kidney stone surgery|PROCEDURE: Endoscopic kidney stone surgery|PROCEDURE: Endoscopic kidney stone surgery|PROCEDURE: Non-invasive kidney stone treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Treatment With Ipilimumab and Nivolumab Compared to Treatment With Ipilimumab Alone in Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Melanoma of Unknown Primary|Mucosal Melanoma|Unresectable Cutaneous Melanoma|Unresectable Melanoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of the Effects of Alpha Lipoic Acid on Oxidative Stress
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Alpha lipoic acid at 3 doses compared to placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Role of Coumadin in Preventing Thromboembolism in Atrial Fibrillation (AF) Patients Undergoing Catheter Ablation
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: Coumadin|DRUG: Coumadin|DRUG: Coumadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Efficacy of a Non-Invasive Measure of Intracranial Pressure
Status: RECRUITING
Conditions: Intracranial Pathology|Intracranial Hypertension
Interventions: PROCEDURE: Phase contrast magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Superior Capsular Reconstruction Versus. Partial Repair for Irreparable Rotator Cuff Tears
Status: UNKNOWN
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: superior capsular reconstuction|PROCEDURE: partial rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Prostate Cancer|Radical Prostatectomy
Interventions: COMBINATION_PRODUCT: Microdevice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Methylprednisolone With or Without Daclizumab in Treating Patients With Acute Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Daclizumab|DRUG: methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of BGT-002 Tablets in Subjects With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: NASH
Interventions: DRUG: BGT-002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial Comparing Transradial Catheterization With or Without Spasmolytic Drugs
Status: COMPLETED
Conditions: Cardiac Catheterisation
Interventions: DRUG: Nitroglycerin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigation of V520 in an HIV Vaccine Proof-of-Concept Study (V520-023)
Status: TERMINATED
Conditions: AIDS|HIV Infections
Interventions: BIOLOGICAL: Trivalent MRKAd5 HIV-1 gag/pol/nef (1.5x10^10 ad-vg/dose)|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Rivaroxaban in Left Ventricular Thrombus
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Left Ventricular Thrombus
Interventions: DRUG: Rivaroxaban|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab and Dinaciclib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia
Interventions: DRUG: Dinaciclib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Ofatumumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study to Evaluate the Pharmacokinetics of BAT1806 vs Actemra® in Healthy Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BAT1806 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding Study of Birabresib (MK-8628) in Participants With Recurrent Glioblastoma Multiforme (MK-8628-002)
Status: TERMINATED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Birabresib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protein Timing, Lean Mass, Strength and Functional Capacity Gains in Postmenopausal Women
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Protein and carbohydrate supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Apelin as a Potential Treatment for Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Cardiovascular Diseases|Endothelial Dysfunction
Interventions: OTHER: [Pyr]apelin-13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Saffron as Anti Inflammatory Agent In Patients With Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: saffron supplement for IBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Piezosurgical vs Conventional Exodontia Surgery in Healthy and Patients With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Surgery|Tooth Extraction Status Nos
Interventions: PROCEDURE: piesosurgical extraction|PROCEDURE: conventional extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Financial Incentives to Improve Medication Adherence
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Bipolar Disorder|Depression
Interventions: OTHER: Wellth - Financial Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of a HiRes™ Optima Sound Processing Strategy for the HiResolution™ Bionic Ear
Status: COMPLETED
Conditions: Severe to Profound Hearing Loss|in Adult Users of Advanced Bionics HiResolution™ Bionic Ear System
Interventions: DEVICE: Control first, then Experimental|DEVICE: Experimental first, then Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Wurn Technique and Mercier Therapy in Women With Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: OTHER: Wurn Technique|OTHER: Mercier Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Virtual Assistance for Self-Care Management and Mental Health Promotion in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Depression, Anxiety|Mental Health Disorder|Old Age; Debility
Interventions: DEVICE: Smart Speaker Echo Dot|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnetic Resonance Spectroscopy Studies of Acute Hypoxic and Hyperoxic Breathing in Healthy Volunteers
Status: WITHDRAWN
Conditions: Healthy
Interventions: OTHER: 16% O2 gas in breathed air|OTHER: 26% O2 gas in breathed air
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial
Status: COMPLETED
Conditions: ST Elevation Acute Myocardial Infarction
Interventions: DRUG: Exenatide|OTHER: Remote Ischemic Conditioning (RIC)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carbetocin on Myocardial Repolarization Dynamics in Obstetrics Study
Status: COMPLETED
Conditions: Cardiac Arrythmias
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Small-diameter Closed Thoracic Drainage Tube Fixation Method
Status: COMPLETED
Conditions: Pulmonary Wedge Resection
Interventions: PROCEDURE: fixed with the triple-buffer system|PROCEDURE: fixed using the conventional lifting platform method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tenting Abutment Technique Versus Screw"Tent-Pole" Technique for Augmentation of Posterior Atrophic Mandible
Status: RECRUITING
Conditions: Posterior Atrophic Mandible
Interventions: PROCEDURE: Tenting abutment technique|PROCEDURE: Tent pole technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MOMSonLINE2 ; A Pilot Study Testing Recruitment and Retention of Women of Color to an Online Support Group for Bereaved Mothers
Status: COMPLETED
Conditions: Stillbirth|Grief|Infant Death
Interventions: BEHAVIORAL: BabyCenter site and the community group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Patient Reported Outcome (PRO) and Physical Activity in Japanese Patients With HR+/HER2- Advanced Breast Cancer Treated With Palbociclib Plus Endocrine Therapy or Endocrine Monotherapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Wearable device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metformin Treatment in Infants After Perinatal Brain Injury
Status: TERMINATED
Conditions: Hypoxic Ischemic Encephalopathy of Newborn|Premature Birth
Interventions: DRUG: Metformin Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Statin|DRUG: ACE inhibitor|DRUG: Placebo|DRUG: Combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DAAOI-1 Treatment for Treatment-resistant Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: DAAOI-1|DRUG: DAAOI-1|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Advanced Pancreatic Ductal Adenocarcinoma|Locally Advanced Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Ductal Adenocarcinoma|Refractory Pancreatic Ductal Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8|Stage IV Pancreatic Cancer AJCC v8|Unresectable Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: DDX5 Degrader FL118|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Effect of Radiation Therapy to Immuno Status in HIV-cancer Patients
Status: UNKNOWN
Conditions: To Study Immunostatus of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT|To Study HIV Viral Load of HIV-cancer Patients Who Recived RT Befor RT and Last Week of RT
Interventions: RADIATION: Radiation therapy|OTHER: Venepuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acetyl-L-carnitine in Combination With a Cisplatin-containing Chemotherapy as First Line Treatment of Advanced or Metastatic Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Acetylcarnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study About Preventive Treatment of Folliculitis Induced by Epidermal Growth Factor Receptor Inhibitors
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Diprosone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Breath Regulation and Yogic Exercise An Online Therapy for Calm and Happiness During the COVID-19 Pandemic
Status: TERMINATED
Conditions: Job Stress|Workplace Stress|Compassion Fatigue|Psychological Trauma|Healthcare Workers|Healthcare Providers
Interventions: OTHER: Sudarshan Kriya Yoga (SKY)|OTHER: Health Enhancement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: Non-renorrhaphy|PROCEDURE: Renorrhaphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triclosan, Triclocarban, and the Microbiota
Status: COMPLETED
Conditions: Triclosan Effects on Microbial Flora
Interventions: OTHER: triclosan/triclocarban-containing personal care products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion
Status: TERMINATED
Conditions: Cervical Spondylosis Symptomatic Neurological Compression
Interventions: BEHAVIORAL: Collar|BEHAVIORAL: No Collar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Spirulina capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT