pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Interferential Electrical Stimulation on Pain Perception and Disability Level on Interstitial Cystitis
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DEVICE: interferential current|DRUG: Propiverine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma
Status: RECRUITING
Conditions: Recurrent Glioblastoma|Recurrent Gliosarcoma
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Function Through Primary Care Treatment of Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure for Primary Care (PE-PC)|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Expansion Device in Tracheostomized Patients Therapies in Tracheostomized Patients
Status: NOT_YET_RECRUITING
Conditions: Postoperative Complications|Rehabilitation|Postoperative Care
Interventions: COMBINATION_PRODUCT: Pulmonary Expansion Device (PED)|PROCEDURE: Conventional management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Retrospective Cohort Study for Main Postoperative Complications After SARS-CoV-2 Infection
Status: NOT_YET_RECRUITING
Conditions: Intestines Cancer|Pulmonary Cancer|Liver Cancer|Trauma|Fractures, Bone|Gynecologic Disease
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Landmark Guided Midline Versus Pre-procedural Ultrasound Guided Paramedian at L5S1 for Spinal Anaesthesia
Status: COMPLETED
Conditions: Anaesthesia
Interventions: PROCEDURE: Conventional landmark guided midline spinal anaesthesia|PROCEDURE: pre-procedure ultrasound guided L5S1 paramedian spinal|DEVICE: spinal anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Neoadjuvant Pegylated Liposomal Doxorubicin and Cyclophosphamide +/- Trastuzumab Followed by Docetaxel in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Beverage Media Campaign and Added-sugar Warning Labels
Status: COMPLETED
Conditions: Attitude|Intention
Interventions: BEHAVIORAL: Control bar code label|BEHAVIORAL: Warning label|BEHAVIORAL: Informational campaign poster about added-sugar warning labels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effectiveness of the USG and CBCT Combined With Intraoral Scanning Determing the Gingival Phenotype in the Healthy Periodontium
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Diagnostic tests: Determination of the gingival phenotype, measure gingival thickness and width of keratinized tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pembrolizumab Cyclophosphamide and Lenalidomide for Patients With Relapsed Multiple Myeloma
Status: WITHDRAWN
Conditions: Myeloma Multiple
Interventions: DRUG: Cyclophosphamide|DRUG: Lenalidomide|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Granisetron in Diabetic Parturients Decrease Spinal Induced Hypotension
Status: COMPLETED
Conditions: Spinal-induced Hypotension
Interventions: DRUG: Granisetron 0.1 MG/ML|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Rehabilitation Technology in Orthopedic and Neurological Rehabilitation to Increase Therapy Dosage: an Exploratory Study
Status: UNKNOWN
Conditions: Arthroplasty|Neurologic Disorder
Interventions: DEVICE: i-ACT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Fluzoparib Combined With QL1101 Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Fluzoparib|BIOLOGICAL: QL1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Artemisinin-based Combination Therapy and Quinine on Treatment Failure and Resistance in Uncomplicated Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether/Lumefantrine|DRUG: Artesunate/Amodiaquine|DRUG: Quinine + Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the Relative Fecal Abundance of BLSE and the Digestive Microbiota be Predictive of the Risk of Infection in a Carrier Patient?
Status: RECRUITING
Conditions: Enterobacteria Infections
Interventions: OTHER: Control (Patients colonized rectally with ESBL-producing enterobacteria without antibiotic pressure)|OTHER: Case (Patients colonized rectally with ESBL-producing enterobacteriaceae, with antibiotic pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis
Status: NOT_YET_RECRUITING
Conditions: Osteonecrosis of the Femoral Head|Avascular Necrosis of the Femoral Head
Interventions: PROCEDURE: Core Decompression|PROCEDURE: Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Monitor of Vascular Volume Fluid Shifts
Status: WITHDRAWN
Conditions: Blood Loss
Interventions: DIAGNOSTIC_TEST: phonocardiographic measurement: InnoVital Systems|DIAGNOSTIC_TEST: phonocardiographic measurement: ThinkLabs StethOne|DIAGNOSTIC_TEST: physiological measurements: BIOPAC|DIAGNOSTIC_TEST: physiological measurements: Masimo Radical-7|DIAGNOSTIC_TEST: physiological measurements: CoVa Monitoring System 2|DIAGNOSTIC_TEST: Thoracic impedance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome, High Grade
Interventions: PROCEDURE: Infusion of autologous CIK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin C Injection on Fatigue in Workers After Work
Status: COMPLETED
Conditions: Fatigue
Interventions: DIETARY_SUPPLEMENT: Ascorbic acid (Vitamin C)|DIETARY_SUPPLEMENT: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study of Travoprost 0.004% Compared to Latanoprost 0.005% in Patients With Chronic Angle-Closure Glaucoma
Status: COMPLETED
Conditions: Glaucoma, Angle-Closure|Ocular Hypertension
Interventions: DRUG: Travoprost (0.004%)|DRUG: Latanoprost (0.005%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Use of BVS in ST-segment Elevation Myocardial Infarction (STEMI): the BVS STEMI STRATEGY-IT Prospective Registry
Status: UNKNOWN
Conditions: ST-elevation Myocardial Infarction (STEMI)
Interventions: PROCEDURE: Primary percutaneous coronary intervention (PPCI)|DEVICE: Bioresorbable Vascular Scaffold (BVS ABSORB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baminercept, a Lymphotoxin-Beta Receptor Fusion Protein, for Treatment of Sjögren's Syndrome
Status: TERMINATED
Conditions: Primary Sjögren's Syndrome
Interventions: BIOLOGICAL: Baminercept|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Cohort Study of Risk Factors and Novel Methods of Skin Lesion Assessments in Adults With Atopic Dermatitis, Alopecia Areata, Psoriasis or Vitiligo
Status: RECRUITING
Conditions: Alopecia Areata|Vitiligo|Atopic Dermatitis|Psoriasis
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of AMG 706 or Bevacizumab, in Combination With Paclitaxel Chemotherapy, as Treatment for Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Breast Tumors|Breast Cancer|Locally Recurrent and Metastatic Breast Cancer
Interventions: DRUG: AMG 706 placebo|DRUG: Bevacizumab|DRUG: AMG 706|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Map Study -Determination of Myocardial Relaxation Times Values in Healthy Volunters
Status: COMPLETED
Conditions: Normal Myocardial T1, T2 and T2* Values
Interventions: OTHER: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Performance of Short Fiber Reinforced Resin Modified Glass Ionomer Restorations in Cervical Carious Teeth (1y Randomized Clinical Trial)
Status: COMPLETED
Conditions: Cervical Caries
Interventions: PROCEDURE: restoration of cervical carious teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Knowledge, Attitude and Practice of Dental Students About COVID-19
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Corona Virus Infection|Acute Lung Injury|Fever|Myalgia|Cough|Dyspnea|Septic Shock|Bleeding
Interventions: BEHAVIORAL: Knowledge, Attitude, Practice, Awareness, Preference
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Ustekinumab, a Human Monoclonal Anti-IL-12/IL-23 Antibody, in Patients With Behçet Disease
Status: COMPLETED
Conditions: Behçet Disease
Interventions: DRUG: Subcutaneous Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of a New Combination of 2 Marketed Medications (Esomeprazole and Naprosyn) Versus Naprosyn Alone
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PN400|DRUG: Naprosyn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Usefulness of BiClamp Forceps for Liver Resection: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Hepatobiliary Disease
Interventions: PROCEDURE: Clamp-Crushing technique|DEVICE: BiClamp forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing Arimidex Tablet and Anastrozole ODF in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Safety|Pharmacokinetics
Interventions: DRUG: Anastrozole ODF|DRUG: Arimidex tablet|DRUG: Anastrozole ODF|DRUG: Arimidex tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Intensity Weight Loss for Young Adults
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Behavioral Weight Loss (BWL)|BEHAVIORAL: BWL + Autonomous Motivation|BEHAVIORAL: BWL + Extrinsic Motivation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AMG 386 in Combination With Paclitaxel and Carboplatin in Subjects With Ovarian Cancer
Status: COMPLETED
Conditions: Carcinoma|Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cancer
Interventions: DRUG: AMG 386, paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Subcostal TAP Block and Local Anesthetic Infiltration After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain|Subcostal Transversus Abdominis Plane Block|Gall Bladder Disease
Interventions: PROCEDURE: Ultrasound guided subcostal transversus abdominis plane block|PROCEDURE: Wound site local anesthetic infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Of 8 Mg Fesoterodine Extended-Release Tablets (Toviaz™) In Healthy Subjects
Status: COMPLETED
Conditions: Treatment of Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Fesoterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of an Amino-Acid-Based Blend on Human Growth Hormone (hGH) and Fibromyalgia (FM) Symptoms
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DIETARY_SUPPLEMENT: amino acid-based blend
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Therapy for Postpartum Lactation
Status: COMPLETED
Conditions: Lactation|Cesarean
Interventions: DEVICE: True AT with magnetic pellets|DEVICE: Sham AT with Medulla Junci
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient Reported Outcomes Following Cancer of the Rectum
Status: RECRUITING
Conditions: Sphincter Ani Incontinence|Rectal Cancer
Interventions: PROCEDURE: Open Total Mesorectal Excision|PROCEDURE: Laparoscopic Total Mesorectal Excision|PROCEDURE: Robotic Total Mesorectal Excision|PROCEDURE: Transanal Total Mesorectal Excision
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Abraxane Plus Hormonal Therapy as Initial Treatment of Unresectable or Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Abraxane|DRUG: Leuprolide|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Envafolimab Combined With Abraxane and Cisplatinas as Neoadjuvant Treatment for Resectable Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Immunotherapy;Envafolimab; Esophageal Cancer
Interventions: DRUG: Envafolimab|DRUG: Abraxane|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of HFpEF With Nitrate Supplement
Status: COMPLETED
Conditions: Heart Failure With Normal Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Active lozenge|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of autoloGous UncondItioneD pEripheral Nerve Tissue Delivery to the Substantia Nigra (GUIDE)
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: PROCEDURE: Peripheral Nerve Tissue Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action Plan to Enhance Self-management and Early Detection of Exacerbations in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Action plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the THERMOCOOL SMARTTOUCH Surround Flow (SF) Catheter With the TRUPULSE Generator for Treatment of Drug Refractory Symptomatic PAFOUS
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Pulsed Field (PF) /Radiofrequency (RF) Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying the Impact of Product Packaging in a Virtual Store Environment
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Experimental Drink: Nutrition claim on fruit drinks|BEHAVIORAL: Control Drink: No nutrition claim|BEHAVIORAL: Experimental snack: Text warning|BEHAVIORAL: Experimental snack: Graphic warning|BEHAVIORAL: Control snack: barcode label
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Examining the Impact of Transcranial Focused Ultrasound (tFUS) on Reward Neural Circuitry
Status: RECRUITING
Conditions: Impulsive Behavior
Interventions: DEVICE: tFUS|DEVICE: Sham tFUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ocular Hemodynamic Effects of Nitrovasodilators in Healthy Subjects
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Nitroglycerin|DRUG: Isosorbide-Dinitrate|DRUG: Sodium-nitroprusside|DRUG: Physiologic saline solution (control substance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Misoprostol Versus Vaginal Dinoprostone For Induction Of Labour: A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Labour Induction
Interventions: DRUG: Misoprostol|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Certolizumab in Crohn's Disease Patients With Loss of Response or Intolerance to Infliximab
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Certolizumab pegol|BIOLOGICAL: Certolizumab pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: JNJ-10450232 / Not yet marketed|DRUG: JNJ-10450232 / Not yet marketed|DRUG: JNJ-10450232 / Not yet marketed|DRUG: acetaminophen / Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Neuro-protective Effect of Granulocyte-colony Stimulating Factor on Early Stage Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: G-CSF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears
Status: ENROLLING_BY_INVITATION
Conditions: Rotator Cuff Tears
Interventions: DEVICE: Arthroscopic rotator cuff repair with BioBrace® Implant augmentation.|PROCEDURE: Arthroscopic rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Parental Presence on Dental Fear
Status: COMPLETED
Conditions: Dental Fear
Interventions: PROCEDURE: Restorative procedure|DRUG: Maxillary infiltration anesthesia with 2%Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PK of TAF and TDF for PrEP in Pregnant and Postpartum Women
Status: COMPLETED
Conditions: Hiv
Interventions: DRUG: Tenofovir alafenamide|DRUG: Tenofovir Disoproxil Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone in Prevention of Respiratory Morbidity in Elective Caesarean Section in Term Fetus
Status: COMPLETED
Conditions: Transient Tachypnea of the Newborn
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy With the Approved JAK Inhibitors or in Which Therapy With the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined
Status: NOT_YET_RECRUITING
Conditions: Myelofibrosis，MF
Interventions: DRUG: Tagraxofusp|DRUG: Pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADV-TK Improves Outcome of Recurrent High-Grade Glioma
Status: COMPLETED
Conditions: Malignant Glioma of Brain|Glioblastoma
Interventions: BIOLOGICAL: ADV-TK/GCV|PROCEDURE: Surgery|DRUG: systemic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Surgical Drilling Protocols in Posterior Maxilla
Status: ACTIVE_NOT_RECRUITING
Conditions: Missing Teeth
Interventions: PROCEDURE: undersized drilling technique|PROCEDURE: single drilling technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIRT Followed by CIS-GEM Chemotherapy Versus CIS-GEM Chemotherapy Alone as 1st Line Treatment of Patients With Unresectable Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Cisplatin-gemcitabine|DEVICE: Radiation: SIRT + chemotherapy (cisplatin-gemcitabine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolomic Approach During Exercise Testing in Myalgia Induced by eXercise
Status: RECRUITING
Conditions: Metabolic Myopathy
Interventions: DIAGNOSTIC_TEST: a supra-maximal exercise test on a cycloergometer.|DIAGNOSTIC_TEST: handgrip muscle activity test.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Reverse vs. Forward ICARE Training Interventions
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurological Injury|Neurological Diseases or Conditions
Interventions: BEHAVIORAL: Forward First ICARE Training|BEHAVIORAL: Reverse First ICARE Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Molecular Weight of Oat β-glucan on Its Ability to Lower Serum Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Wheat bran|DIETARY_SUPPLEMENT: 3g high MW|DIETARY_SUPPLEMENT: 4g medium MW|DIETARY_SUPPLEMENT: 3g medium MW|DIETARY_SUPPLEMENT: 4g low MW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CRH on Duodenal Markers and Gastric Sensorimotor Function
Status: COMPLETED
Conditions: GI Motility Disorder
Interventions: DRUG: Corticotropin-release hormone|DRUG: Corticotropin-release hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endovascular Repair With In Situ nEedle feNestration of Left Subclavian Artery to Treat AoRtic Dissection(RISEN STAR):A Multicenter Prospective Trial.
Status: RECRUITING
Conditions: Aortic Dissection|Left Subclavian Artery Occlusion|Vascular Diseases|Interventional Therapy
Interventions: BEHAVIORAL: In situ fenestration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Erector Spina Plane Block(ESPB)'s Effectiveness on Patients With Lumbar Radiculopathy
Status: UNKNOWN
Conditions: Radiculopathy|Radiculopathy Lumbar|Pain, Back
Interventions: PROCEDURE: Erector Spinae Plane Block|DRUG: NSAID|BEHAVIORAL: Home Exercise Programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stopping Upper Respiratory Infections and Flu in the Family: The Stuffy Trial
Status: COMPLETED
Conditions: Respiratory Tract Infections|Common Cold
Interventions: BEHAVIORAL: Hand hygiene and educational material|DEVICE: Mask, alcohol and hand sanitizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
Status: RECRUITING
Conditions: Adrenal Insufficiency|Polymyalgia Rheumatica|Giant Cell Arteritis
Interventions: DRUG: Hydrocortisone|DRUG: Placebo for hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pilates Exercise and Whatsapp Text-Based Support Program on Premenstrual Syndrome (PMS) Symptoms
Status: COMPLETED
Conditions: Premenstrual Syndrome|Physical Exercise|Women's Health
Interventions: OTHER: A support program with pilates exercise and whatsapp text message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Experimental Bone Marrow Transplant Protocol
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Chronic Myeloid Leukemia|Acute Myelocytic Leukemia|Myelodysplastic Syndromes|Myeloproliferative Disorders
Interventions: DEVICE: Isolex 300i Stem Cell Selection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Jigsaw Technique Used in Critical Article Review on Critical Thinking Disposition and Communication Skills
Status: ACTIVE_NOT_RECRUITING
Conditions: Education, Distance|Students, Nursing
Interventions: BEHAVIORAL: Jigsaw Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing a DTaP-HB-PRP~T Combined Vaccine With Tritanrix HepB/Hib™, Concomitantly With OPV in Healthy Infants
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Influenza
Interventions: BIOLOGICAL: DTaP-HB-PRP~T combined vaccine|BIOLOGICAL: Tritanrix-HepB/Hib™ vaccine|BIOLOGICAL: Oral poliomyelitis vaccine (OPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
Status: COMPLETED
Conditions: Myopia|Astigmatism|Hyperopia|Refractive Error
Interventions: DEVICE: FID 120947A contact lens disinfecting solution|DEVICE: Boston Simplus multi-action solution|DEVICE: Gas permeable contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of CP-751,871 in Combination With Docetaxel and Prednisone in Patients With Hormone Insensitive Prostate Cancer (HRPC)
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: CP-751,871|DRUG: docetaxel|DRUG: prednisone|DRUG: docetaxel|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Chlorepheniramine Maleate Reducing Postoperative Agitation
Status: COMPLETED
Conditions: Agitated; State, Acute Reaction to Stress
Interventions: DRUG: Preemptive chlorepheniramine maleate intravenous injection|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Intervention Before and After Surgery in Older Adults With Lung Cancer and Their Family Caregivers
Status: WITHDRAWN
Conditions: Caregiver|Lobectomy Patient|Lung Carcinoid Tumor|Lung Non-Small Cell Carcinoma
Interventions: OTHER: E-mail|BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention|OTHER: Text Message
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness and Underlying Mechanisms of Parent Management Training and Mindful Parenting Program
Status: COMPLETED
Conditions: Parent Management Training|Mindfulness|Mindful Parenting Training
Interventions: BEHAVIORAL: Positive Parenting Program, Mindful Parenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Study of the Baska Mask Vs Proseal Laryngeal Mask Regarding Airway Sealing Pressure
Status: COMPLETED
Conditions: Baska Mask
Interventions: DEVICE: Group A : Baska Mask Airway|DEVICE: Group B: Proseal Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Durability of Virologic Response and/or Viral Resistance Patterns in Participants With Chronic Hepatitis C Who Have Been Previously Treated With Grazoprevir (MK-5172) (MK-5172-017)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Concurrent Training on Physical Fitness and Body Composition in Obese Individuals
Status: RECRUITING
Conditions: Obesity
Interventions: OTHER: Concurrent Training|OTHER: Strength Training|OTHER: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Efficacy Study of JNS024 Extended Release (ER) in Japanese and Korean Patients With Chronic Malignant Tumor-Related Cancer Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Oxycodone CR|DRUG: R331333 (referred to as JNS024 ER or CG5503)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate|DRUG: Doxorubicin hydrochloride|DRUG: Zidovudine|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Releasing Balloon in Patients Presenting With In-Stent Restenosis
Status: COMPLETED
Conditions: In-stent Coronary Artery Restenosis
Interventions: DEVICE: Paclitaxel Releasing Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of the CapBuster System for the Crossing of CTO's in Coronary Arteries
Status: NOT_YET_RECRUITING
Conditions: Chronic Total Occlusion of Coronary Artery
Interventions: DEVICE: CapBuster System Medical Device for the Crossing of Chronic Total Occlusions in Coronary Arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Compare the PK and Safety of Naproxcinod in Hepatic Impaired Patients and Matching Healthy Subjects
Status: COMPLETED
Conditions: Liver Disease
Interventions: DRUG: naproxcinod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma
Status: NOT_YET_RECRUITING
Conditions: GBM|DIPG Brain Tumor|Medulloblastoma
Interventions: BIOLOGICAL: Vγ9Vδ2 T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plasmablast Trafficking and Antibody Response in Influenza Vaccination (SLVP021 2011-2014)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluzone® (IM)|BIOLOGICAL: Fluzone® Intradermal (ID)|BIOLOGICAL: 2011-2012 FluMist®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Alga Dunaliella Bardawil on Psoriasis
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DIETARY_SUPPLEMENT: Alga Dunaliella Bardawil placebo|DIETARY_SUPPLEMENT: Dunaliella Bardawil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Using Humanized CART Directed Against BCMA (ARI0002h) in Patients With Relapsed/Refractory Multiple Myeloma to Proteasome Inhibitors, Immunomodulators and Anti-CD38 Antibody.
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Adult differentiated autologous T-cells with anti-BCMA specificity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endometrial Preparation by Short Course of Letrozole Before Hysteroscopic Removal of Endocavitary Lesions
Status: UNKNOWN
Conditions: Myoma;Uterus
Interventions: DRUG: Letrozole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pain and Stress Management for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Stress and Emotions|BEHAVIORAL: Thoughts and Behaviors|BEHAVIORAL: Brain and Body
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma (NHL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Indolent B-cell Non-Hodgkin's Lymphoma
Interventions: DRUG: ME-401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate EP-104IAR in Adults With Eosinophilic Esophagitis (EoE).
Status: RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: EP-104IAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMRT Plus PD-1 Blockade and Lenvatinib for HCC With PVTT (Vp3) Before Liver Transplantation
Status: UNKNOWN
Conditions: Liver Cancer|Liver Transplant; Complications|Hepatocellular Carcinoma|Portal Vein Thrombosis|Radiotherapy; Complications
Interventions: RADIATION: intensity-modulated radiotherapy|COMBINATION_PRODUCT: Pembrolizumab|DRUG: Sintilimab|DRUG: Camrelizumab|DRUG: Tislelizumab|DRUG: Lenvatinib Mesylate Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Project PREVAM : Prospective Comparison of Capsule Endoscopy Pillcam II™ Versus Colonoscopy
Status: COMPLETED
Conditions: Adenomatous Polyps|Cancer
Interventions: DEVICE: Comparison of capsule endoscopy Pillcam II™ versus colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Whole-body Electromyostimulation (WB-EMS) Training in Participants With Pre-diabetes
Status: RECRUITING
Conditions: Pre-diabetes
Interventions: OTHER: whole-body electromyostimulation training|OTHER: activity tracker|OTHER: evidence-based lifestyle education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Two Urinary Catheters of Different Lengths for Female Use, in Intermittent Catheterization
Status: COMPLETED
Conditions: Catheterization
Interventions: DEVICE: A=SpeediCath Compact 7 cm and B=POBE 10 cm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Pioglitazone Administered to Patients With Friedreich's Ataxia: Proof of Concept
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: DRUG: pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Pharmacokinetics (PK) Study of Trans Sodium Crocetinate (TSC) in Patients With Intermittent Claudication
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: DRUG: Trans sodium crocetinate (TSC)|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketone Ester Intervention in Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Drinking|Alcohol Use Disorder
Interventions: DIETARY_SUPPLEMENT: Ketone Ester "(R)-3-hydroxybutyl (R)-3-hydroxybutyrate"|DRUG: Isocaloric dextrose placebo|OTHER: Alcohol drinks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Safety and Pharmacokinetics of BIIB104 in Healthy Japanese and Non-Japanese Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BIIB104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Stimulation for Persistent Fatigue Treatment Post-COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study)
Status: UNKNOWN
Conditions: Optic Nerve Diseases
Interventions: DRUG: Erythropoietin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Effect Of Ceriter Stride One (CSO) on FOG and Falling in pwP
Status: COMPLETED
Conditions: Gait, Festinating|Parkinson Disease|Device Adherence
Interventions: DEVICE: CSO_without cueing|DEVICE: CSO_cueing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Tolerability Study of TAK-165 in Subjects With Tumors Expressing HER2
Status: COMPLETED
Conditions: Breast Neoplasm|Pancreatic Neoplasm|Lung Neoplasm|Ovarian Neoplasm|Renal Neoplasm
Interventions: DRUG: TAK-165
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Cryosurgery and NK Immunotherapy for Advanced Esophageal Cancer
Status: COMPLETED
Conditions: Metastatic Esophageal Cancer
Interventions: DEVICE: Cryosurgery|BIOLOGICAL: NK immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A QoL Intervention for Young African American Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: OTHER: Educational Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking Cessation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Asthma|Smoking
Interventions: OTHER: Biofeedback and Neurofeedback Training|DRUG: Varenicline use for smoking cessation|OTHER: Sham Neurofeedback|OTHER: Passive Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anti-Scarring Efficacy and Safety of Intradermal Juvista (Avotermin) in Healthy Males
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Juvista (avotermin) plus placebo, standard-care (within-subject controls)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility & Effect of a Tele-rehabilitation Program in Idiopathic Pulmonary Fibrosis (IPF)
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BEHAVIORAL: Virtual Autonomous Physiotherapist Agent (VAPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E Combined With Fruquintinib and Tislelizumab in Microsatellite Stabilized Metastatic Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Microsatellite Stable Colorectal Carcinoma
Interventions: DRUG: Vitamin E|DRUG: Fruquintinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG PET/CT-based Prognostic Model for Predicting Outcome in Patients With Peripheral T-cell Lymphoma
Status: UNKNOWN
Conditions: Lymphoma, T-Cell, Peripheral
Interventions: DEVICE: 18F-FDG PET/ CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Study of Futibatinib and Pembrolizumab in Metastatic Microsatellite Stable Endometrial Carcinoma
Status: RECRUITING
Conditions: Metastatic Cancer|Endometrium Cancer|Endometrial Carcinoma
Interventions: DRUG: Futibatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Stump Infection After Laparoscopic Hysterectomy
Status: TERMINATED
Conditions: Laparoscopic Hysterectomy|Vaginal Infection
Interventions: PROCEDURE: Total laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Appropriate Medication Use in Dutch Terminal Care
Status: RECRUITING
Conditions: Palliative Care|Terminal Care|Medication Therapy Management|Clinical Decision Support System (CDSS)|Quality of Life
Interventions: DEVICE: CDSS-OPTIMED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE