pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bone Marrow Derived Allogeneic Mesenchymal Stromal Cells to Non-healing Diabetic Foot Wounds
Status: TERMINATED
Conditions: Diabetic Foot Ulcer
Interventions: BIOLOGICAL: mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia
Status: COMPLETED
Conditions: Adult T-Cell Leukemia (ATL)
Interventions: DRUG: LMB-2|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant PD-1 Inhibitor (Sintilimab), Anlotinib Combined With Chemotherapy in Resectable Stage IIA-IIIB NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Sintilimab|Lung Cancer|Anlotinib|Chemotherapy
Interventions: DRUG: Neoadjuvant therapy 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Cisplatin 1|DRUG: Cisplatin 2|DRUG: Docetaxel|DRUG: Xeloda|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Computerized Cognitive Behavioral Treatment for Insomnia: Increasing Access to Insomnia Treatment to Decrease Suicide Risk
Status: COMPLETED
Conditions: Insomnia|Physical Health Functioning|Mental Health Functioning
Interventions: BEHAVIORAL: Computerized Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-Acetyl Cysteine in Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania
Interventions: DRUG: Placebo|DRUG: N-Acetyl Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: mFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases
Status: RECRUITING
Conditions: Colorectal Carcinoma|Liver Metastases
Interventions: DRUG: mFOLFOXIRI regimen|DRUG: mFOLFOX regimen|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Frailty Care Pathways in Rural Primary Care: a Feasibility Study
Status: WITHDRAWN
Conditions: Frailty
Interventions: OTHER: Frailty care pathway for older people in a rural primary care setting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pectin, Aging and Intestinal Barrier Function
Status: COMPLETED
Conditions: Healthy Young Adults|Healthy Elderly
Interventions: DIETARY_SUPPLEMENT: Pectin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Sorafenib Plus HAIC of FOLFOX vs. Sorafenib Plus HAIC of OXA for Advanced HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: HAIC of FOLFOX|DRUG: HAIC of OXA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Neuroblastoma|Refractory Anaplastic Large Cell Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Neuroblastoma
Interventions: DRUG: Crizotinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study With Rituximab, Cyclophosphamide, Doxorubicin Liposomal (Myocet®), Vincristine, Prednisone, (R-COMP) to Treat Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Prednisone|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Tramadol Hydrochloride/Dexketoprofen Trometamol|DRUG: Tramadol Hydrochloride/Paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cross-Education on Shoulder Arthroscopy
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries|Rotator Cuff Repair
Interventions: OTHER: Cross-Education|OTHER: Blood-Flow Restriction Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of BMS-986403 in Participants With Relapsed and/or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma
Interventions: DRUG: BMS-986403|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of COVID-19 Vaccine, AdCLD-CoV19-1
Status: TERMINATED
Conditions: COVID-19|Vaccines
Interventions: BIOLOGICAL: AdCLD-CoV19-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic Effects of Standard Cardiopulmonary Resuscitation (CPR), Active Compression Decompression CPR With an Inspiratory Impedance Device, and Standard CPR With an Intrathoracic Pressure Regulator During Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest|Sudden Cardiac Death
Interventions: DEVICE: ACD-CPR|DEVICE: ITPR|PROCEDURE: S-CPR|DEVICE: Impedance Threshold Device (ITD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CANadian Study in Patients With Wet AMD, Evaluating the Efficacy and Safety of Switching From Intravitreal Aflibercept to RanIbizumab
Status: WITHDRAWN
Conditions: Wet Age-related Macular Degeneration (Wet AMD)
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Assess the Influence of Simultaneous CYP3A4 and P-glycoprotein Inhibition on E7080 Pharmacokinetics Following Single Dose Oral Administration of 5 mg E7080 to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ketoconazole-placebo|DRUG: placebo-ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ritual Prenatal Multivitamins for Pregnancy
Status: RECRUITING
Conditions: Pregnancy Related|Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: Ritual Epre Multivitamin-mineral supplement|DIETARY_SUPPLEMENT: control MVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Intervention Study to Evaluate a Website Tailored to New Dads to Promote Mental Health
Status: UNKNOWN
Conditions: Mental Health in Expectant First-time Fathers
Interventions: BEHAVIORAL: Psychoeducational modules to prevent/reduce depression|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ketamine Infusion for Rapid Reduction of Suicidality in Pediatrics
Status: RECRUITING
Conditions: Suicidal Ideation
Interventions: DRUG: Ketamine Injectable Solution|DRUG: Midazolam Injectable Solution|DRUG: Normal Saline 0.9% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Renal Sodium Excretion After Salt Loading in Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: 0.9% Sodium Chloride|DRUG: Furosemide 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Collaborative Services in Primary Care for Treating Children With Behavior Disorders
Status: COMPLETED
Conditions: Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Doctor-office collaborative care (DOCC) management|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cetirizine in Treatment of Localized Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Topical Cetirizine 1 %|DRUG: Topical betamethasone valerate 0.1%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sintilimab in Combination With Nab-paclitaxel in Patients With HNSCC (Head and Neck Squamous Cell Carcinoma )
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Cancer
Interventions: DRUG: Sintilimab and Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Added to Levobupivacaine Improves Postoperative Analgesia
Status: UNKNOWN
Conditions: Brachial Plexus Anesthesia|Analgesia
Interventions: PROCEDURE: supraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early Weightbearing Versus Non-weightbearing After Operative Treatment of an Ankle Fracture
Status: UNKNOWN
Conditions: Ankle Fracture|Rehabilitation
Interventions: PROCEDURE: Early weightbearing|PROCEDURE: Non-weightbearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: At-Home Care for Subjects With Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Dental Plaque
Interventions: DEVICE: ADA approved Manual Toothbrush|DEVICE: Marketed Power Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unsweetened Sparkling Water and Changes in Sweetness Perception in Adolescents
Status: COMPLETED
Conditions: Obesity, Adolescent|PreDiabetes
Interventions: OTHER: Unsweetened flavored sparkling water
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Human Immunodeficiency Virus (HIV) Postexposure Prophylaxis (PEP) With Darunavir/Ritonavir (DRV/r)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: DRUG: Darunavir/Ritonavir (DRV/r)|DRUG: Lopinavir in fixed combination with Ritonavir|DRUG: Zidovudine|DRUG: NRTIs|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia
Status: RECRUITING
Conditions: β-thalassemia
Interventions: BIOLOGICAL: β-globin restored autologous hematopoietic stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism
Interventions: DRUG: Anticoagulation with heparin|DEVICE: EkoSonicTM Endovascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Volociximab in Combination With Gemcitabine in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Volociximab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Therapeutic Effects of Intra-Articular Injection of Ozone and Corticosteroid in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Ozone - oxygen Therapy|OTHER: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a 4-Month Post-Renal Transplant Dose Reduction of Tacrolimus(ADEQUATE)
Status: UNKNOWN
Conditions: De Novo Transplant Disease
Interventions: DRUG: Tacrolimus targeted half-dose|DRUG: Tacrolimus targeted plain dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children
Status: UNKNOWN
Conditions: Surgery|Anesthesia Intubation Complication
Interventions: OTHER: MAVEPPIC: MAsk VEntilation with Paratracheal Pressure In Children
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens
Status: COMPLETED
Conditions: Ametropia
Interventions: DEVICE: enfilcon A|DEVICE: galyfilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicentre Prospective Study Evaluating an Off-loading Mattress Overlay System in Healing of Stage 3 Pressure Ulcers
Status: RECRUITING
Conditions: Pressure Ulcer
Interventions: DEVICE: Dabir Mattress Overlay System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: DEVICE: Evoke Spinal Cord Stimulation (SCS) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin-cyclophosphamide Combined With Atezolizumab
Status: COMPLETED
Conditions: Breast Cancer|Cervix Cancer|Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: carbplatin, cyclophophamide, atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innoventric Trillium™ Stent Graft First-in-Human (FIH) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: Trillium™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Cognitive Ability, General|Fatigue|Pain|Psychosocial Deprivation|Radiation Toxicity|Skin Abnormalities
Interventions: GENETIC: DNA analysis|GENETIC: gene expression analysis|OTHER: enzyme-linked immunosorbent assay|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|PROCEDURE: adjuvant therapy|PROCEDURE: assessment of therapy complications|PROCEDURE: quality-of-life assessment|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: breast irradiation|RADIATION: external beam radiation therapy|RADIATION: hypofractionated radiation therapy|RADIATION: intensity-modulated radiation therapy|RADIATION: whole breast irradiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-Label Study of RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM)
Status: COMPLETED
Conditions: Recurrent Glioblastoma Multiforme
Interventions: DEVICE: NovoTTF-100A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Interscalene and Suprascapular Nerve Block on Analgesia Consumption After Adhesive Capsulitis Surgery
Status: COMPLETED
Conditions: Shoulder Surgery
Interventions: PROCEDURE: interscalene brachial plexus block|PROCEDURE: suprascapular nerve block|PROCEDURE: Group Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: HZ/su|COMBINATION_PRODUCT: Flu D-QIV|BIOLOGICAL: mRNA-1273
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Ragweed-SPIRE in Subjects With Ragweed Allergies and Asthma
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis|Asthma
Interventions: BIOLOGICAL: Ragweed-SPIRE|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary Hypertension
Status: COMPLETED
Conditions: Thalassemia|Hypertension, Pulmonary
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation Method by Rhythmic, Vocal and Embodied Musical Learning for Stabilized Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: cognitive remediation by musical training sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)
Status: COMPLETED
Conditions: Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions: DRUG: ANX005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing of the Integrated Rapid Access to HIV Prevention Program for People Who Inject Drugs Program
Status: COMPLETED
Conditions: HIV Prevention Program|Opioid-use Disorder
Interventions: BEHAVIORAL: iRaPID|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Investigational Agent for the Treatment of Complicated Intra-Abdominal Infections or Acute Pelvic Infections (0826-038)
Status: COMPLETED
Conditions: Infections|Pelvic Infections
Interventions: DRUG: MK0826, ertapenem sodium|DRUG: Comparator: Ticarcillin/Clavulanate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma
Status: COMPLETED
Conditions: Medulloblastoma
Interventions: RADIATION: Standard Fractionation Regimen|RADIATION: Hyperfractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Brain Diseases|Central Nervous System Diseases|Delirium, Dementia, Amnestic, Cognitive Disorders|Dementia|Mental Disorders|Nervous System Diseases|Neurodegenerative Diseases|Tauopathies
Interventions: OTHER: L-Leucine 13C6
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Aerobic Interval and Continuous Exercise Trainings in Patients With Chronic Heart Failure
Status: UNKNOWN
Conditions: Cardiac and Hemodynamic Response|Blood Flow Distribution and Oxygen Uptake Efficiency|Hemorheology Modulated by Erythrocyte|Atherothrombosis Modulated by Monocyte|Angiogenesis Modulated by EPC
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Chronic Kidney Disease
Interventions: DRUG: Semaglutide|DRUG: Placebo (Semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Re-irradiation of Recurrent Cervical Cancer by IMRT
Status: UNKNOWN
Conditions: Cervical Cancer|Radiation Toxicity|Recurrent Cervical Carcinoma
Interventions: DEVICE: intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation Prior to Botox Injections for Spasmodic Dysphonia
Status: ENROLLING_BY_INVITATION
Conditions: Spasmodic Dysphonia
Interventions: DRUG: Zinc gluconate supplement|DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of MOPs During Orthodontic Movement in Periodontitis Patients
Status: RECRUITING
Conditions: Stage IV Periodontitis|Orthodontic Tooth Movement
Interventions: PROCEDURE: Micro-ostoperforations (MOPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management After Shoulder Arthroplasty
Status: UNKNOWN
Conditions: Caffeine|Pain, Joint
Interventions: PROCEDURE: Total Shoulder Arthroplasty|DRUG: Caffeine Pill|DRUG: Percocet 10Mg-325Mg Tablet|DRUG: Zofran 4Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventilation/Perfusion PET/CT With Galligas and 68Ga-MAA for Regional Lung Function Assessment After Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism|Dyspnea
Interventions: PROCEDURE: Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine vs. Propofol for Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: dexmedetomidine|DRUG: Propofol|DRUG: Dexemedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Evaluate the Safety and Efficacy of Mechlorethamine(MCH) 0.04% Formulation in Mycosis Fungoides
Status: COMPLETED
Conditions: Mycosis Fungoides
Interventions: DRUG: 0.04% Mechlorethamine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of DOXIL and Temsirolimus in Resistant Solid Malignancies
Status: COMPLETED
Conditions: Resistant Solid Malignancies
Interventions: DRUG: Temsirolimus|DRUG: Pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis|Cartilage Injury
Interventions: DEVICE: shock wave device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of GSK Meningococcal Group B Vaccine and 13-valent Pneumococcal Vaccine Administered Concomitantly With Routine Infant Vaccines to Healthy Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Bexsero (GSK Biologicals' Meningococcal group-B vaccine/ rMenB+OMV NZ)|BIOLOGICAL: Prevnar13|BIOLOGICAL: Pediarix|BIOLOGICAL: Hiberix|BIOLOGICAL: Rotarix|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax|BIOLOGICAL: Placebo (saline water)|BIOLOGICAL: Prevnar 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Project My Heart Your Heart: Pacemaker Reuse
Status: ENROLLING_BY_INVITATION
Conditions: Device Related Infection|Device Malfunction|Bradycardia
Interventions: DEVICE: Reconditioned Pacemaker|DEVICE: New Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Extension Study of the Safety and Efficacy of Aldurazyme® (Laronidase) in Mucopolysaccharidosis I (MPS I) Patients
Status: COMPLETED
Conditions: Mucopolysaccharidosis I|Hurler's Syndrome|Hurler-Scheie Syndrome|Scheie Syndrome
Interventions: BIOLOGICAL: Aldurazyme|BIOLOGICAL: Aldurazyme|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Title: "Intervention Based on Didactic Model for Suicidal Behavior in the Framework of Impulsivity and Ideations."
Status: UNKNOWN
Conditions: Suicidal Ideation and Behavior|Impulsivity
Interventions: OTHER: Didactic model for suicidal behavior in the framework of impulsivity and ideations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: PIoglitazone for PrEvention of Restenosis in Diabetic Patients
Status: UNKNOWN
Conditions: Coronary Atherosclerosis|Coronary Restenosis|Diabetes
Interventions: DRUG: Pioglitazone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding, Efficacy and Safety of BI 655064 in Patients With Active Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: BI 655064 dose 1|DRUG: BI 655064 dose 2|DRUG: BI 655064 dose 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRIMA PFO Migraine Trial
Status: TERMINATED
Conditions: Migraine|Migraine With Aura|Patent Foramen Ovale|PFO
Interventions: DEVICE: AMPLATZER® PFO Occluder Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 1b Study of AdV-tk + Valacyclovir Combined With Radiation Therapy for Malignant Gliomas
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: BIOLOGICAL: AdV-tk|DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Trial of Botulinum Toxin for Gastroparesis
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: Botulinum toxin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Continuous Intravenous Infusion of PSC 833 and Vinblastine in Patients With Metastatic Renal Cancer
Status: COMPLETED
Conditions: Kidney Neoplasms|Neoplasm Metastasis
Interventions: DRUG: PSC 833|DRUG: vinblastine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Left Atrial Ablation With Permanent Pacemaker or ImplanTable Loop Recorder Follow-UP
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: AF Ablation with Ablation Frontiers Technology|PROCEDURE: AF Ablation with LASSO catheter|DEVICE: Reveal XT|DEVICE: Permanent Dual Chamber Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Heart-focused Anxiety in Patients With Heart Failure and ICD
Status: COMPLETED
Conditions: Heart Failure Patients Before and After ICD Implantation
Interventions: DEVICE: Implantable Cardioverter Defibrillator (ICD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effectiveness of a Self-managed Digital Exercise Programme to Prevent Falls in Older Community-dwelling People
Status: COMPLETED
Conditions: Accidental Falls
Interventions: BEHAVIORAL: Safe Step - digital exercise program|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting
Status: NOT_YET_RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Modified laterally stretched technique with a connective tissue graft.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: BFR (Blood-Flow Restricted exercise)|OTHER: Standard rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: MIECH: The Minimally Invasive Endoscopic Surgery With the Axonpen System for Spontaneous Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Cerebral Hemorrhage|Intracranial Hemorrhage|Basal Ganglia Hemorrhage
Interventions: DEVICE: Axonpen system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Biomarker Expression in Samples From Young Patients With Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: GENETIC: microarray analysis|GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of FS VH S/D 500 S-apr (Tisseel) as an Adjunct to Sutured Dural Repair in Cranial Surgery
Status: COMPLETED
Conditions: Cerebrospinal Fluid Leak
Interventions: DRUG: FS VH S/D 500 s-apr|DEVICE: DuraSeal Dural Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Lupus Nephritis
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Added Value of Cognition-targeted Exercise Versus Symptom-targeted Exercise for Multiple Sclerosis Fatigue
Status: COMPLETED
Conditions: Physical and Rehabilitation Medicine
Interventions: OTHER: cognition-targeted exercise|BEHAVIORAL: Cognitive behavioral therapy|OTHER: Standardized physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quetiapine Augmentation for Treatment-resistant PTSD
Status: COMPLETED
Conditions: Combat Disorders|Stress Disorders, Post-Traumatic
Interventions: DRUG: Open Label (OL) Paroxetine|DRUG: Placebo|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inulin,SCFA Production and Metabolic Response
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DIETARY_SUPPLEMENT: 13C inulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Lower Extremity Blood Flow Restriction Training on Power, and Muscle Size.
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Seated Rowing Ergometer|OTHER: Deadlift|OTHER: Blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation and Prophylaxis of Anomia in Primary Progressive Aphasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Aphasia, Primary Progressive|Anomia|Alzheimer Disease
Interventions: BEHAVIORAL: Phonological|BEHAVIORAL: Orthographic|BEHAVIORAL: Semantic|BEHAVIORAL: Lexical|BEHAVIORAL: Untrained
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Combined With Bevacizumab for Brain Metastases From Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Brain Metastases|Non Small Cell Lung Cancer|Sintilimab|Bevacizumab
Interventions: DRUG: sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family and Childhood Development: The Next Generation ('Kizazi Kijacho')
Status: RECRUITING
Conditions: Parenting|Early Child Development
Interventions: OTHER: Digital application supported CHW Parenting Intervention|OTHER: Unconditional Cash Transfer only Intervention fixed amount|OTHER: Unconditional Cash Transfer Intervention|OTHER: Unconditional Cash Transfer only Intervention vary amount
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of CS-3150 Compared to Olmesartan in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: CS-3150|DRUG: olmesartan medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Direct Current Stimulation (TDCS) in Drug-resistant Partial Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DEVICE: STARSTIM|DEVICE: sham TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glenohumeral Versus Subacromial Steroid Injections for Impingement Syndrome With Mild Shoulder Stiffness
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Adhesive Capsulitis of Shoulder
Interventions: PROCEDURE: Ultrasound-guided glenohumeral space triamcinolone, lidocaine and saline injection|PROCEDURE: Ultrasound-guided subacromial space triamcinolone, lidocaine and saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab vs. Bevacizumab Combined With Triamcinolone for Neovascular AMD
Status: UNKNOWN
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: bevacizumab|DRUG: bevacizumab + triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin E Fortified Whey Drink on Nutritional, Inflammatory and Oxidative Markers in Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: whey drink,|DIETARY_SUPPLEMENT: whey drink fortified with vitaminE|DIETARY_SUPPLEMENT: vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platinum-based Chemotherapy With Atezolizumab and Niraparib in Patients With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Carcinoma
Interventions: DRUG: Placebo|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Niraparib|DRUG: Gemcitabine|DRUG: Pegylated liposomal doxorubicin (PLD)|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Distress Tolerance for Benzodiazepine Discontinuation
Status: TERMINATED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Distress Tolerance - Benzodiazepine Discontinuation (DT-BD)|BEHAVIORAL: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: IFN beta 1a 44 mcg TIW|DRUG: Curcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proprioceptive Neuromuscular Facilitation in the Flexibility and Strength of Flexor Muscles and Hamstrings
Status: COMPLETED
Conditions: Proprioceptive Disorders
Interventions: OTHER: Experimental|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Benefits of Nicotinamide Riboside Upon Cognition and Sleep
Status: RECRUITING
Conditions: Cognitive Impairment|Sleep Quality
Interventions: DIETARY_SUPPLEMENT: Nicotinamide riboside|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Regenafil Versus Demineralized Freeze Dried Bone Allograft (DFDBA) for Periodontal Defects
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: DFDBA|DEVICE: Regenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of SRX251 Capsules in Healthy Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SRX251
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Risk Factors in Coeliac Disease: a Series of Studies
Status: RECRUITING
Conditions: Coeliac Disease
Interventions: OTHER: Dietary intervention|OTHER: Standard of care|DIAGNOSTIC_TEST: Cardiovascular risk-related parameters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Radiofrequency Ablation in Patients With Ventricular Arrhythmia Undergoing CABG
Status: UNKNOWN
Conditions: MI Related Malignant Ventricular Arrhythmia
Interventions: PROCEDURE: unipolar or bipolar radiofrequency ablation+CABG|PROCEDURE: CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Topical Oxytocin Gel in Post-Menopausal Women
Status: COMPLETED
Conditions: Menopause Related Conditions
Interventions: OTHER: oxytocin gel|OTHER: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Supplemental Oxygen Delivery Via Demand Versus Continuous Flow in Hypoxemic COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: 1 continuous flow oxygen supplementation|DEVICE: 2 demand delivery liquid oxygen supplementation|DEVICE: 3 demand delivery oxygen supplementation via concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes of Autologous Transobturator Rectus Fascia Sling for Treatment of Female Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Autologous rectus Fascia TOT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Chondrocyte Transplantation For Articular Cartilage Regeneration
Status: COMPLETED
Conditions: Tear; Knee, Cartilage, Articular
Interventions: DEVICE: Arthroscopic matrix encapsulated chondrocyte implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Corneal Infiltrates Secondary to Epidemic Keratoconjunctivitis
Status: COMPLETED
Conditions: Adenoviral Keratoconjunctivitis
Interventions: DRUG: FLUCON®|DRUG: Cyclosporine A eye drops 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pediatric Nursing Students' Self-efficacy Regarding Pediatric Medication Administration and, Clinical Comfort and Worry: A Study on a Two-group Pre-post-test Design Comparing Nurse and Peer Mentoring
Status: COMPLETED
Conditions: Medication Administration|Mentoring|Comfort
Interventions: OTHER: Peer mentoring|OTHER: Nurse mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electrochemical and Electrophysiological Study
Status: ENROLLING_BY_INVITATION
Conditions: Cognition|Medically Intractable Epilepsy
Interventions: OTHER: Behavioral testing under intracranial monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pivotal Trial of Dermagraft(R) to Treat Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Dermagraft(R)|DEVICE: Profore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Veterans With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Recurrent
Interventions: BEHAVIORAL: Hyp-8|BEHAVIORAL: Hyp-2 w recordings|BEHAVIORAL: Hyp-8|BEHAVIORAL: Hyp-8 w recordings|BEHAVIORAL: Hyp-2 w recordings|BEHAVIORAL: Hyp-8|BEHAVIORAL: Hyp-8 w recordings|BEHAVIORAL: BIO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biweekly Docetaxel in Combination With Capecitabine as First-Line Treatment in Patients With Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: DRUG: docetaxel and capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT