pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effects of Red Spinach Extract on Physical Performance Following Chronic Resistance Training in Trained Males
Status: COMPLETED
Conditions: Sports
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Red Spinach Extract (RSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)
Status: TERMINATED
Conditions: Immune Reconstitution Inflammatory Syndrome|Leukoencephalopathy, Progressive Multifocal
Interventions: DRUG: Methylprednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Language Therapy With rTMS in Aphasia
Status: COMPLETED
Conditions: Aphasia
Interventions: BEHAVIORAL: Intensive Language-Action Therapy (ILAT)|DEVICE: Repetitive navigated Transcranial Magnetic Stimulation during naming training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of Different Antidepressants With Dietary Supplements
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: L-methylfolate|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PATHWAY-RCT: Preventing Admission To Hospital With Attr cardiomyopathY
Status: NOT_YET_RECRUITING
Conditions: Cardiac Amyloidosis
Interventions: COMBINATION_PRODUCT: Telemonitoring service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate Efficacy and Safety of ASC and Fibringlue or Fibringlue in Patients With Crohn's Fistula
Status: RECRUITING
Conditions: Crohn's Fistula
Interventions: BIOLOGICAL: ASC|DRUG: Fibringlue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Measurement of Natural Killer Cell Activity in Whole Blood in Men Being Screened for Prostate Cancer With Biopsy
Status: TERMINATED
Conditions: Immunity, Innate|Prostatic Neoplasm
Interventions: DIAGNOSTIC_TEST: IVDD for NK cell activity in whole blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Azilsartan Medoxomil, Once Daily (QD), Co-Administered With Amlodipine in Participants With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan Medoxomil and amlodipine|DRUG: Azilsartan Medoxomil and amlodipine|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Food on the Bioavailability of Telmisartan / Ramipril Fixed Dose Combination in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan/Ramipril, fixed dose combination tablet|OTHER: high fat, high caloric meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnosis for Sleep Quality in Caregivers of Individuals With Alzheimer's Disease
Status: COMPLETED
Conditions: Poor Quality Sleep|Caregiver Stress|Alzheimer's Disease (Incl Subtypes)
Interventions: BEHAVIORAL: Self-Administered Hypnosis|BEHAVIORAL: Self-Administered White Noise Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BPI-361175 Tablets in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Carcinoma
Interventions: DRUG: BPI-361175
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel in mCRPC Patients With AR-V7 Positive Circulating Tumor Cells (CTCs)
Status: UNKNOWN
Conditions: Circulating Tumor Cell|Metastatic Prostate Cancer
Interventions: DRUG: Cabazitaxel|OTHER: Antihistamine|OTHER: Corticosteroid|OTHER: H2 antagonist|OTHER: Antiemetic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in DMARD-naïve Patients With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis, DMARD-naive and Early Disease Patients
Interventions: DRUG: CR6086|DRUG: Methotrexate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain, Opioids and Pro-Inflammatory Immune Responses
Status: TERMINATED
Conditions: Pro-inflammatory Activity|Immunologic Activity Alteration
Interventions: DRUG: Fentanyl|OTHER: Cold pressor test|OTHER: Fentanyl plus cold pressor test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717.
Status: RECRUITING
Conditions: Prion Disease
Interventions: DRUG: ION717|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy
Status: COMPLETED
Conditions: Cytokine Release Syndrome
Interventions: DRUG: Itacitinib|DRUG: Immune effector cell therapy|DRUG: Placebo|BIOLOGICAL: Yescarta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study for the Efficacy and Safety of Ropeginterferon Alfa-2b in Moderate COVID19.
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: P1101 (Ropeginterferon alfa-2b)|PROCEDURE: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: DF289|DRUG: DF277|DRUG: DF289 plus DF277
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Additional Use of Preoperative Azithromycin Decrease Posthysterectomy Infections
Status: RECRUITING
Conditions: Infection Post Op|Hysterectomy|Antibiotics|Prophylactic
Interventions: DRUG: Azithromycin Pill + Cefuroxime|DRUG: Placebo + Cefuroxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Tolerability of COR-101 in Hospitalized Patients With Moderate to Severe COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: COR-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Bevel Direction of Puncture Needle on Success Rate and Complications During Central Venous Catheterization
Status: COMPLETED
Conditions: Central Venous Catheterization
Interventions: DEVICE: bevel direction during central venous catheterization|DEVICE: bevel direction during central venous catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Seated Physical Activity in Ageing
Status: UNKNOWN
Conditions: Frail Elderly Syndrome|Frailty|Physical Activity
Interventions: OTHER: Exercise Intervention 1: Move It Or Lose It (MIOLI)|OTHER: Exercise Intervention 2: Machine-based resistance training intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Compare VMP With HDM Followed by VRD Consolidation and Lenalidomide Maintenance in Patients With Newly Diagnosed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib, Melphalan, Prednisone (VMP)|DRUG: 1 or 2 cycle(s) HDM (High Dose Melphalan)|DRUG: 2 cycles of Bortezomib, Lenalidomide, Dexamethasone (VRD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S9920 Busulfan Compared With Cyclophosphamide in Patients Undergoing Total-Body Irradiation Plus Peripheral Stem Cell Transplantation for Advanced Myelodysplastic Syndrome or Related Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: methotrexate|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Modulation of ABCC9 Pathways by Nicorandil for the Treatment of Hippocampal Sclerosis of Aging
Status: RECRUITING
Conditions: Dementia|Mild Cognitive Impairment
Interventions: DRUG: Nicorandil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Adaptive Multisite Prevention of University Student Suicide
Status: RECRUITING
Conditions: Suicide
Interventions: BEHAVIORAL: Treatment As Usual (TAU)|BEHAVIORAL: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1|BEHAVIORAL: Dialectical Behavior Therapy (DBT) - Phase 2|BEHAVIORAL: Maintenance/Monitoring - Phase 2|BEHAVIORAL: Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relative Bioavailability, Safety and Tolerability of Two Tablet Formulations of BIIL 284 BS
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 BS Tablet FF|DRUG: BIIL 284 BS tablet C|OTHER: standard breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS
Status: COMPLETED
Conditions: Acute Pancreatitis|Systemic Inflammatory Response Syndrome
Interventions: DRUG: CM-4620 Injectable Emulsion or CM-4620-IE|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation in the Pain Management of Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Radio-frequency ablation|DRUG: Intra-articular steroids|DEVICE: Pulsed Radio-frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Rehabilitation Outcomes After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty|Osteoarthritis
Interventions: BEHAVIORAL: Functional Strength Integration (FSI)|BEHAVIORAL: Control Group (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additive Effects of Dental Bite Pads During Gymnastic Exercises for the Relief of Chronic Non-specific Neck Pain in Working Women and Men at a VDU Workplace
Status: COMPLETED
Conditions: Chronic Neck Pain|TMD|Temporomandibular Dysfunction
Interventions: DEVICE: gymnastics plus silicon dental bite pad|OTHER: gymnastics only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Open-Label Study to Assess the Safety and Preliminary Efficacy of PRF 110 in Open Herniorrhaphy Surgery
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: PRF110- oily solution (Ropivacaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Manipulation on Coccydynia
Status: COMPLETED
Conditions: Coccyx Disorder|Pelvic Floor; Weak|Stretch
Interventions: OTHER: Exercises|OTHER: Coccyx Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Multicentre, Randomized, Two-arm Blinded Study to Assess the Efficacy and Safety of Two LXE408 Regimens for Treatment of Patients With Primary Visceral Leishmaniasis
Status: RECRUITING
Conditions: Primary Visceral Leishmaniasis
Interventions: DRUG: LXE408|OTHER: Placebo|DRUG: AmBisome®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid, Hemorrhage and Transfusions After Combined Aortic Valve Replacement and Coronary Artery Bypass Surgery.
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DRUG: Tranexamic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Chemoradiotherapy Sequential Fluzoparib in Pan-solid Tumors
Status: NOT_YET_RECRUITING
Conditions: PARP Inhibitor for Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Fluzoparib monotherapy or Fluzoparib with Camrelizumab(Only non-small cell lung cancer arm) ,or Fluzoparib combined with capecitabine (only rectal cancer arm))
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Joint Infant and Young Child Nutrition Program and Malnutrition Prevention
Status: COMPLETED
Conditions: Growth Failure|Good Infant and Young Child Feeding Practices
Interventions: OTHER: MNP + IYCN counseling + cooking demonstrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Tinospora Crispa-extract Product Compared With the Acetaminophen
Status: COMPLETED
Conditions: Patients With Body Temperature Between 37.8-38.5|No Sign of Infection|No Liver and Kidney Problem
Interventions: DRUG: Tinospora Crispa-extract Product|DRUG: Acetaminophen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurostimulation for the Treatment of Post-Stroke Aphasia
Status: RECRUITING
Conditions: Post-stroke Aphasia
Interventions: DEVICE: tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for Non-invasive Ventilation After Chest Trauma
Status: COMPLETED
Conditions: Thoracic Injuries
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vildagliptin Versus NPH Insulin add-on to Glimepiride in Type 2 Diabetes Mellitus Patients.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LAF237|DRUG: Protaphane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Tools to Diagnose Invasive Aspergillosis Infections in ICU Patients With COVID-19 and Other Conditions.
Status: RECRUITING
Conditions: Invasive Pulmonary Aspergillosis
Interventions: BIOLOGICAL: respiratory sample|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: N-DOSE: A Dose Optimization Trial of Nicotinamide Riboside in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) and Head and Neck Cancer Pain (HNC) (TENS & HNC)
Status: COMPLETED
Conditions: Head Cancer|Neck Cancer|Pain
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Double-masked Uveitis Treatment
Status: COMPLETED
Conditions: Uveitis; Posterior, Disorder
Interventions: DRUG: DE-109 44 ug|DRUG: DE-109 440 ug|DRUG: DE-109 880 ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Three Periodontal Therapies in Current Smokers and Non-Smokers
Status: COMPLETED
Conditions: Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: Scaling and root planing|DRUG: Metronidazole|DRUG: Amoxicillin|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI
Status: COMPLETED
Conditions: Tbi|Intracranial Edema|Brain Edema|Craniocerebral Trauma|Head Injury|Brain Hemorrhage, Traumatic|Subdural Hematoma|Brain Concussion|Head Injuries, Closed|Epidural Hematoma|Cortical Contusion|Wounds and Injuries|Disorders of Environmental Origin|Trauma, Nervous System|Brain Injuries
Interventions: BEHAVIORAL: Therapist Guided Face to Face Family Problem Solving|BEHAVIORAL: Therapist Guided Online Family Problem Solving|BEHAVIORAL: Self-Guided Online Family Problem Solving
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Sympathetic Activity and Splanchnic Capacitance in Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Trimethaphan|DRUG: Nitroglycerin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: IntraVitreal Triamcinolone Acetonide: Preventing Raised Eye-pressure by Tracking Elevations After Topical Steroids
Status: UNKNOWN
Conditions: Vitreoretinal Disease|Ocular Hypertension
Interventions: DRUG: Prednisolone 1% topical eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of Combined Deferasirox, Vitamin D and Azacytidine in High Risk MDS
Status: UNKNOWN
Conditions: MDS
Interventions: DRUG: Deferasirox, Vitamin D and Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Immersive Virtual Reality Combined With Task-Specific Training on Hemiplegic Arm Function Following Stroke: A Single Case Series Study.
Status: RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: VR immersive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Locally Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: JBI-802
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
Status: ENROLLING_BY_INVITATION
Conditions: Traumatic Brain Injury|Post-traumatic Epilepsy
Interventions: BEHAVIORAL: In-Person Outcome Assessment|PROCEDURE: 3T Magnetic Resonance Imaging (MRI)|BEHAVIORAL: Clinical Visit|PROCEDURE: Blood Draw|PROCEDURE: EEG|BEHAVIORAL: Telephone Outcome Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Manikin To Patient Intubation: Does It Translate?
Status: COMPLETED
Conditions: Intubation; Difficult or Failed
Interventions: PROCEDURE: Intervention: Receives Training|OTHER: Intervention: Control No Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gemcitabine and Radiation Therapy in Treating Patients With Cancer of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Pre-exercise Feeding on Bone Turnover Biomarkers
Status: NOT_YET_RECRUITING
Conditions: Osteopenia or Osteoporosis
Interventions: OTHER: Breakfast only|OTHER: FAST|OTHER: FED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine Versus Placebo in Primary Sjögren's Syndrome
Status: COMPLETED
Conditions: Primary Sjögren's Syndrome
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent
Status: TERMINATED
Conditions: Major Depressive Disorder With Suicidal Ideation With Intent
Interventions: DRUG: MIJ821 Intravenous Injection|DRUG: Placebo Intravenous Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate in Treating Patients With Melanoma
Status: COMPLETED
Conditions: Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: methylphenidate hydrochloride|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Study to Compare the Bioavailability of Three Halobetasol Propionate 0.05% Topical Creams
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Halobetasol Propionate 0.05% Cream-Reference Product|DRUG: Halobetasol Propionate 0.05% Cream-Test product 1|DRUG: Halobetasol Propionate 0.05% Cream-Test Product 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multicenter Study Evaluating the Performance of the Assay of Anti-hinge Region Antibodies in the Diagnosis of Progressive Forms of IgA Nephropathy
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: sargramostim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|DRUG: pegaspargase|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRO1184 for Advanced Solid Tumors
Status: RECRUITING
Conditions: Platinum-Resistant Ovarian Cancer|Platinum Sensitive Ovarian Cancer (PSOC)|High Grade Epithelial Ovarian Cancer|High Grade Serous Ovarian Cancer|Primary Peritoneal Carcinoma|Fallopian Tube Cancer|Endometrial Cancer|Non-small Cell Lung Cancer|Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer (NSCLC)|Mesothelioma|Breast Adenocarcinoma|Triple Negative Breast Cancer|Hormone Receptor-positive/Her2 Negative Breast Cancer
Interventions: DRUG: PRO1184|DRUG: PRO1184 intravenous infusion of PRO1184|DRUG: PRO1184 intravenous infusion of PRO1184|DRUG: PRO1184 intravenous infusion of PRO1184
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging Combining Biomarkers for Identifying Long-term Cognitive Dysfunction and Delirium
Status: NOT_YET_RECRUITING
Conditions: Postoperative Cognitive Dysfunction|Postoperative Delirium|Cerebral Small Vessel Diseases|Covert Postoperative Stroke
Interventions: DIAGNOSTIC_TEST: multimodal MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Interscalene and Combined Costoclavicular-suprascapular Blocks for Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Surgery|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Suprascapular Nerve Block with 5ml bupivicaine 0.5%|PROCEDURE: costoclavicular Block 10ml bupivicaine 0.5%|PROCEDURE: Interscalene Brachial Plexus Block 15ml bupivicaine 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Dose Escalation|Safety|Preliminary Efficacy|Advanced Solid Tumors|Metastatic Breast Cancer|Advanced Pancreatic Adenocarcinoma|Metastatic Colorectal Cancer|Recurrent Glioblastoma Multiforme|Gastric Cancer|Gastroesophageal Junction Cancer|Triple Negative Metastatic Breast Cancer|Hormone Receptor Positive (ER+/PR+, and Her2-) Metastatic Breast Cancer
Interventions: DRUG: LDE225|DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes
Status: RECRUITING
Conditions: Anxiety Disorder|Depression|Genetic Disorder|Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia
Status: COMPLETED
Conditions: Preeclampsia Severe|Preeclampsia Postpartum
Interventions: DRUG: Vitamin C|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss
Interventions: DEVICE: Topcon Specular Microscope SP-1P|DEVICE: Konan Specular Microscope CELLCHEK XL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Observational Study on Efficacy, Safety and Convenience of Using Mixtard® 30 NovoLet® Alone or Combined With OHA in Treatment of Type 2 Diabetes in Routine Clinical Practice
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic human insulin 30
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anticoagulation Therapy Timing in Atrial Fibrillation After Acute and Chronic Subdural Hematoma
Status: TERMINATED
Conditions: Subdural Hematoma|Atrial Fibrillation
Interventions: DRUG: Direct Acting Oral Anticoagulant starting at Day 30|DRUG: Direct Acting Oral Anticoagulant starting at Day 90
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib Combined With Capecitabine Metronomic Therapy in HER2-postitive Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Pyrotinib|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic Dermatitis: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Chronic Actinic Dermatitis
Interventions: DRUG: Azathioprine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Daily Ultraviolet Therapy to Reduce Cardiovascular Risk Factors
Status: TERMINATED
Conditions: Hypertension
Interventions: DEVICE: Ultraviolet A radiation|DEVICE: Sham irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of INCB054707
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: INCB054707|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Using Pericardial Membrane Versus Titanium Mesh" in Horizontal Alveolar Ridge Augmentation
Status: COMPLETED
Conditions: Horizontal Ridge Augmentation, Histological and Clinical Result
Interventions: PROCEDURE: horizontal alveolar ridge augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on the Influence of Mukbang on Brain Activation in Children With Cancer Based on fMRI
Status: NOT_YET_RECRUITING
Conditions: Children With Cancer
Interventions: COMBINATION_PRODUCT: fMRI + Mukbang videos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic Esophagitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: DIETARY_SUPPLEMENT: Eosinophilic Esophagitis (EoE) food introduction-1st|DIETARY_SUPPLEMENT: Eosinophilic Esophagitis (E0E) food introduction-2nd|DIETARY_SUPPLEMENT: Eosinophilic Esophagitis (EoE) Food introduction-3rd dose|DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Interim 18F-FDG-PET and 18F-FLT-PET for Predicting Treatment Response and Survival in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DIAGNOSTIC_TEST: 18F-fluorothymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Analysis of the Effects of the Osteopathic Manipulative Treatment in Carriers of Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Conventional Group|OTHER: Osteopathic Group|DRUG: Ibuprofen|DRUG: Cyclobenzaprine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Specified Drug-use Survey of the Granular Capsule Formulation of Omega-3 Fatty Acid Ethyl Esters: OCEAN3
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Omega-3 fatty acid ethyl esters|DRUG: Standard antihyperlipidemic therapy other than administration of omega-3 fatty acid ethyl esters (Lotriga).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate How Patients Regard the Benefits and Risks of Low-dose Aspirin for the Prevention of Heart and Blood Vessels Disease and for the Prevention of Cancer of the Colon and Rectum
Status: COMPLETED
Conditions: Cardiovascular Disease|Colorectal Cancer
Interventions: DRUG: Acetylsalicylic acid (Aspirin, BAYE4465)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Bioavailability of Extended Release Metformin HCl Tablet Versus Glucophage XR® Tablets in Healthy Human Volunteers Under Fasting Condition
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: O6-benzylguanine and Carmustine in Treating Patients With Recurrent, Metastatic, or Locally Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helical Tomotherapy, Fludarabine Phosphate, and Melphalan Followed By Allo-HSCT in Hematological Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: fludarabine phosphate|DRUG: melphalan|PROCEDURE: allogeneic hematopoietic stem cell transplantation|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy (COMBO)
Status: TERMINATED
Conditions: Smoking Cessation
Interventions: DRUG: Varenicline|DRUG: Oral Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Medication Reminders|BEHAVIORAL: Tobacco Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADESPI: Adherence to Spiriva® in Patients With COPD (Chronic Obstructive Pulmonary Disease), Measured by Morisky-8 (MMAS-8) Scale, in Routine Medical Practice
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: PROCEDURE: Education
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Central Nervous System Nongerminomatous Germ Cell Tumor|Childhood Central Nervous System Germinoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|RADIATION: Intensity-Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzumab +Pertuzumab, or Combination Trastuzumab + Lapatinib
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Trastuzumab|DRUG: pertuzumab|DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: S-1 Combined With IMRT Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: BI 207127 high fat|DRUG: BI 207127 with Omeprazole|DRUG: BI 207127|DRUG: BI 207127 low fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Picosecond and Nanosecond Q-switched Lasers for Tattoo Removal
Status: COMPLETED
Conditions: Tattoo Removal
Interventions: DEVICE: Picosecond Q-switched Laser Treatment|DEVICE: Nanosecond Q-switched Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Immunomodulatory Effects of Oral Nanocurcumin in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Nanocurcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Laser Interstitial Thermal Therapy Under "Real Time" MRI Guidance for "Minimal Invasive" Treatment of Liver Metastasis
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Liver Neoplasms|Digestive System Neoplasms
Interventions: DEVICE: MR-guided Laser Interstitial Thermal Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DMTA07 Combine With Amlodipine Treatment in Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: AM 5 + DM 0|DRUG: AM 5 + DM 2.5|DRUG: AM 5 + DM 7.5|DRUG: AM 5 + DM 30
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualized Physical Activity and Carotid Plaque Instability
Status: COMPLETED
Conditions: Carotid Atherosclerosis
Interventions: DEVICE: individualized home-based physical activity|OTHER: MRI|BIOLOGICAL: blood sampling|OTHER: Questionnaires|OTHER: 6-minute walk test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Soleus Loading Response During Walking
Status: RECRUITING
Conditions: Healthy|Spastic Hemiparesis|Stroke
Interventions: DEVICE: Soleus loading response in able-bodied participants|DEVICE: Soleus loading response in participants with hemiparesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label, Non-Randomized Trial to Evaluate the Tolerability and Safety of Viramune (Nevirapine) in Adult and Pediatric Patients With Progressive HIV Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Prevalence Of Deleterious Oral Habits Among a Group of School Children in Cairo, Egypt: Cross-Sectional Study
Status: NOT_YET_RECRUITING
Conditions: Habits|Bruxism|Sucking Behavior|Nail Biting
Interventions: OTHER: thired domain of nordic orofcial test-screen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tariquidar-ondansetron Combination in Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Ondansetron 16 mg with Tariquidar|DRUG: Ondansetron 16 mg with Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VEGF Trap in Treating Patients With Solid Tumors or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: ziv-aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Office Based Treatment of Opioid Use Disorder With Technology
Status: UNKNOWN
Conditions: Opioid-use Disorder
Interventions: DEVICE: BupreCare|DRUG: Buprenorphine/naloxone|OTHER: MEMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of MRI for Allergic Broncho-Pulmonary Aspergilloses
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergilloses
Interventions: DEVICE: MRI|DEVICE: CT scan (standard reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicentre, Randomized as a Double Blind Study, Triple Placebo, Comparative of the Efficacy and Safety of an Association Secnidazol-Ciprofloxacin Compared With Amoxicillin-Clavulanic Acid for the Treatment of Uncomplicated Episode of Diverticular Sigmoïditis Among Adults
Status: TERMINATED
Conditions: Diverticular Sigmoïditis
Interventions: DRUG: Secnidazole, ciprofloxacine|DRUG: Amoxicillin-Clavulanic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lumbar and Sacroiliac Manipulation on Football Players
Status: COMPLETED
Conditions: Sports Physical Therapy|Neuromuscular Subluxation of Joint
Interventions: OTHER: Lumbar spinal manipulation|OTHER: Sacroiliac joint manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Thymalfasin Adjuvant Therapy in Hepatitis B Virus (HBV)-Related Hepatocellular Carcinoma (HCC) After Curative Resection
Status: UNKNOWN
Conditions: Curable Hepatitis B Virus-Related Hepatocellular Carcinoma
Interventions: PROCEDURE: curative resection|DRUG: thymalfasin|DRUG: nucleoside analog (suggest to use entecavir)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Pleural Mesothelioma|Unresectable Malignant Neoplasm
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps
Status: COMPLETED
Conditions: Traumatic Lumbar Puncture
Interventions: PROCEDURE: Bedside Ultrasound-Assisted Site Marking|DEVICE: Mindray M7 Ultrasound|PROCEDURE: Routine lumbar puncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: ACU-4429|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer
Status: COMPLETED
Conditions: Thrombosis|Atherothrombosis|Myocardial Infarction|STEMI|NSTEMI - Non-ST Segment Elevation MI|DVT|Pulmonary Embolism|Stroke|Transient Ischemic Attack|Prosthetic Valve Thrombosis|PET
Interventions: DIAGNOSTIC_TEST: 18F-GP1 PET CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE