pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
Status: UNKNOWN
Conditions: Urolithiasis|Renal Colic|Osteopenia
Interventions: DIAGNOSTIC_TEST: CT scan|DIAGNOSTIC_TEST: 24 hour urine collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying Non-motor Symptoms in HSP
Status: COMPLETED
Conditions: SPG4
Interventions: DIAGNOSTIC_TEST: EuroQol five dimensions questionaire (EQ-5D)|DIAGNOSTIC_TEST: Modified Fatigue Impact Scale (MFI)|DIAGNOSTIC_TEST: Brief Pain Inventory (BPI)|DIAGNOSTIC_TEST: Becks Depression Inventory (BDI)|DIAGNOSTIC_TEST: Restless-leg Questionaire (RLS diagnostic criteria)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of a mNGS Workflow for Infection Diagnosis Using Oxford Nanopore Sequencing.
Status: UNKNOWN
Conditions: Bacterial Infections
Interventions: DIAGNOSTIC_TEST: Metagenomic next generation sequencing using Oxford Nanopore|DIAGNOSTIC_TEST: Standard microbiological diagnostic pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: PRospective Multicenter Observational Study on Transfusion Practice in Vv-ECMO Patients: The PROTECMO Study
Status: COMPLETED
Conditions: Extracorporeal Membrane Oxygenation Complication|Transfusion Related Complication|Hemorrhage|Anticoagulant-induced Bleeding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carfilzomib, Cyclophosphamide, Dexamethasone in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Protective Cream Against Radiodermatitis Caused by Radiotherapy.
Status: RECRUITING
Conditions: Radiodermatitis
Interventions: OTHER: experimental cream|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2|Extracorporeal Membrane Oxygenation|ARDS
Interventions: DEVICE: vv-ECMO
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Bone Grafts on Facial Gingival Profile in Maxillary Anterior Single Tooth Replacement
Status: COMPLETED
Conditions: Facial Gingival Profile
Interventions: PROCEDURE: bone graft inside socket only|PROCEDURE: bone graft inside and outside socket|PROCEDURE: no bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone In The Treatment of Heart Failure
Status: RECRUITING
Conditions: Heart Failure With Mid-range Ejection Fraction|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Experimental: Spironolactone|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DLCL002 Protocol for Patients With High Risk Aggressive B-cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma|High-grade B-cell Lymphoma|Transformed Lymphoma
Interventions: DRUG: Rituximab|DRUG: Etoposide|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Lenalidomide|DRUG: Cisplatin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-vivo Extraction of Lead, Cadmium and Tobacco Specific Nitrosamines From Swedish 'Snus' in Regular Snus Users
Status: COMPLETED
Conditions: Smoking Cessation|Harm Reduction
Interventions: PROCEDURE: Buccal Administration of nicotine|PROCEDURE: Buccal Administration of nicotine|PROCEDURE: Buccal Administration of nicotine|PROCEDURE: Buccal Administration of nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Tralokinumab When Delivered Subcutaneously at Different Flow Rates to Healthy Volunteers
Status: COMPLETED
Conditions: Asthma|Healthy Subjects or Volunteers
Interventions: BIOLOGICAL: Tralokinumab 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phosphate Metabolites in Brain of Humans Aged 50+
Status: COMPLETED
Conditions: Basic Science
Interventions: DIETARY_SUPPLEMENT: Peptamen® 1.5 Vanilla|DIETARY_SUPPLEMENT: Boost Plus® Vanilla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of a Psychotherapeutic Intervention Model in Nursing
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: NIC Psychotherapeutic Intervention(s) for Anxiety|DRUG: Psychopharmaceuticals (any drugs prescribed by the psychiatrist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Therapeutic Efficacy of Pimecrolimus Cream With Betamethasone Cream for Discoid Lupus Erythematosus
Status: COMPLETED
Conditions: Discoid Lupus Erythematosus
Interventions: DRUG: Pimecrolimus 1% cream|DRUG: betamethasone valerate 0.1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Validation of Endoscopic Bimodal Imager for the Bladder Cancer Detection
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DEVICE: Strorz (commercial)|DEVICE: CyPaM2 (experimental)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prognostic Factor in the Patients With Benign Prostatic Hyperplasia Who Undergo Holmium Laser Enucleation of the Prostate
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: PROCEDURE: holmium laser enucleation of the prostate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Pramipexole and Bromocriptine Combined With L-dopa in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Pramipexole|DRUG: Bromocriptine|DRUG: Placebo pramipexole|DRUG: Placebo bromocriptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combined Capsular Tension Ring and IOL Implantation for Management of Cataracts
Status: COMPLETED
Conditions: Intraocular Lens Rotation|Capsular Tension Ring
Interventions: DEVICE: capsular tension ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gedatolisib Plus Talazoparib in Advanced Triple Negative or BRCA1/2 Positive, HER2 Negative Breast Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: Gedatolisib|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft and Hard Tissue Changes Around Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Alveolar Ridge
Interventions: PROCEDURE: Placement of dental implant|PROCEDURE: Placement of stock healing abutment|PROCEDURE: Placement of customized CAD/CAM healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Translational Validation Study to Examine KFO179-1 Biomarker Scores for the Prediction and Prognosis of Advanced Primary Resectable Rectal Cancer Stages UICC-II-IV, With a 5-Fluorouracil-based Standard Radiochemotherapy Followed by Total Mesorectal Excision.
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: OTHER: Translational Research and multimodal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Expanded Access Open Label Protocol of Remune (HIV-1 Immunogen) in HIV-1-Infected Adults With CD4 Count 550 Cells /Ml and Greater.
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 Immunogen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Samples From Patients With Chronic Lymphocytic Leukemia Treated on Clinical Trial ECOG-2997
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: cytogenetic analysis|OTHER: flow cytometry|OTHER: fluorescence activated cell sorting|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Combination Therapies on Neck Pain & Muscle Tenderness in Patients With Upper Trapezius MTrPs
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain
Interventions: BEHAVIORAL: MET|BEHAVIORAL: ICT|BEHAVIORAL: Conventional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Vocal Contact (EVC) in the Neonatal Intensive Care Unit
Status: UNKNOWN
Conditions: Early Intervention|Prematurity
Interventions: BEHAVIORAL: Early Vocal Contact|BEHAVIORAL: Behavioral Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|Cardiac Disease
Interventions: DRUG: Glucagon like peptide 1 receptor agonist|DRUG: Sodium-glucose cotransporter 2 inhibitor|DRUG: Dipeptidyl Peptidase 4 Inhibitor|DRUG: Sulfonylurea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact Of The Nurse Enhanced Recovery After Surgery Coordinator On The Compliance In Colorectal Surgery (nursERAS-BCN)
Status: RECRUITING
Conditions: ERAS|Enhanced Recovery|Compliance, Treatment|Compliance, Patient|Nurse's Role|Colon Disease|Rectum Disease
Interventions: OTHER: Nurse Enhanced Recovery After Surgery participation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Randomized Trial of Uncemented Versus Cemented Hemiarthroplasty for Displaced Femoral Neck Fractures
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Uncemented primary bipolar hemiarthroplasty of the hip|PROCEDURE: Cemented primary bipolar hemiarthroplasty of the hip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK
Status: RECRUITING
Conditions: Drug-Drug Interaction
Interventions: DRUG: Methadone and Tizanidine|DRUG: Efavirenz, Methadone and Tizanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Setmelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Firebird 2 Stent in Treatment of Complex Coronary Lesions in Diabetes
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Firebird 2 Cobalt-Chromium Alloyed Sirolimus-Eluting Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthrosis
Interventions: DRUG: Tranexamic Acid - topical|DRUG: Placebo|DRUG: Tranexamic Acid - intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Mass Balance and Biotransformation of [14C]SHR4640 in Chinese Healthy Adult Male Volunteers.
Status: COMPLETED
Conditions: Healthy Adult Male Volunteers
Interventions: DRUG: [14C]SHR4640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
Status: TERMINATED
Conditions: Pre-Diabetes|Major Lung or Abdominal Surgery|Insulin Resistance
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Osteoarthritis, Shoulder
Interventions: DRUG: Liposomal bupivacaine|DRUG: Standard of care analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Palatal Lengthening Using Buccinator Myomucosal Flaps With Furlow Z-plasty Technique for Primary Cleft Palate Repair
Status: COMPLETED
Conditions: Cleft Palate, Unilateral, Complete
Interventions: PROCEDURE: furlow z plasty with buccinator myomucosal flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extra-Corporeal Shock Wave Lithotripsy for Renal and Upper Ureteral Stones in Adults Under Locally Infiltrate d Anaesthetics ; a Clinical Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Stone Ureter
Interventions: DRUG: locally infilterating anaethesia like lidocaine|DRUG: general anaethesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic Tranexamic Acid During Minimally Invasive Myomectomies
Status: RECRUITING
Conditions: Fibroid Uterus|Abnormal Uterine Bleeding|Myoma;Uterus
Interventions: DRUG: Tranexamic Acid|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D and Microvascular Function in Postmenopausal Women
Status: COMPLETED
Conditions: Menopause Related Conditions|Vitamin D Deficiency|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: Blood samples and Microvascular function assessment evaluated through laser-Doppler flowmetry by the LASER speckle contrast analysis (LASCA) device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cardiac Output in Preeclamptic
Status: RECRUITING
Conditions: Echocardiography
Interventions: DRUG: 1000 mL of ringer's acetate solution|DRUG: 250 mL 6% hydroxyethyl starch (Voluven) then 500 mL of ringer's acetate solution then 250 mL of 6% hydroxyethyl starch (Voluven)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation on Pain After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Intravenous lidocaine injection|DRUG: Intraperitoneal lidocaine irrigation group|DRUG: Intravenous normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recto-intercostal Fascial Plane Block and Pecto-intercostal Fascial Plane Block for Cardiac Surgery
Status: RECRUITING
Conditions: Cardiac Disease
Interventions: DRUG: RIFPB block|OTHER: Postoperative analgesia management|DRUG: PIFPB block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community-Based, Client-Centered Prevention Homes to Address the Rural Opioid Epidemic- Aim 3
Status: COMPLETED
Conditions: Drug Use Disorders|Hepatitis C|Harm Reduction|Opioid-use Disorder
Interventions: OTHER: Community-Based, Client-Centered Prevention Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Magnetic Tape on Perceived Spine Pain and Over Ankle Dorsiflexion in Patients With Low Back Pain
Status: COMPLETED
Conditions: Back Pain
Interventions: DEVICE: Magnetic Tape® aplicación|DEVICE: Kinesiology Tape application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in People With Indolent Systemic Mastocytosis
Status: COMPLETED
Conditions: Indolent Systemic Mastocytosis
Interventions: BIOLOGICAL: sarilumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility Usability and Effectiveness of Fully Immersive Horticultural-based Virtual Reality Cognitive Training for Community-dwelling Elderly
Status: RECRUITING
Conditions: Fully Immersive Virtual Reality
Interventions: DEVICE: Fully-immersive VR|BEHAVIORAL: Cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Approach to Upper Extremity Amputation to Augment Volitional Control and Restore Proprioception
Status: RECRUITING
Conditions: Amputation
Interventions: PROCEDURE: Modified amputation procedure|PROCEDURE: Standard amputation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft Donor Site
Status: COMPLETED
Conditions: Palatal Wound
Interventions: DEVICE: Allogenic amnion chorion membrane|DEVICE: Collagen dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Electrically Guided Needle Insertion: Transtracheal Injection
Status: WITHDRAWN
Conditions: Transtracheal Injection|Fibreoptic Intubation
Interventions: PROCEDURE: Transtracheal injection|PROCEDURE: Transtracheal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Jinghua Weikang Capsule in the Treatment of Reflux Esophagitis
Status: NOT_YET_RECRUITING
Conditions: Reflux Esophagitis
Interventions: DRUG: jinghua weikang capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of AL-38583 in the Reduction of Tear Eosinophil Count Following Conjunctival Allergen Challenge
Status: WITHDRAWN
Conditions: Allergic Conjunctivitis
Interventions: DRUG: AL38583 Ophthalmic Solution|DRUG: Maxidex|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Elagolix in Women With Endometriosis
Status: COMPLETED
Conditions: Endometriosis, Pain
Interventions: DRUG: Placebo|DRUG: Elagolix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Milk Oral Immunotherapy in Children to Treat Food Allergy
Status: COMPLETED
Conditions: Milk Hypersensitivity
Interventions: DIETARY_SUPPLEMENT: Milk Oral Immunotherapy|DRUG: Milk Protein Powder|OTHER: Food Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Cytokine Induced Killer Cells (CIK) for Patients With Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Adoptive Immunotherapy
Interventions: DRUG: Adoptive Immunotherapy|BIOLOGICAL: CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cocoa Polyphenols Supplementation on Cardiovascular Risk of Postmenopausal Women
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Placebo of Cocoa flavonoids|DIETARY_SUPPLEMENT: Cocoa flavonoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deep Radiomics-based Fusion Model Predicting Bevacizumab Treatment Response and Outcome in Patients With Colorectal Liver Metastases
Status: COMPLETED
Conditions: The Patients With CRLM Who Benefit More From Bevacizumab
Interventions: DIAGNOSTIC_TEST: Deep radiomics-based fusion model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regulation of Craving in Internet Gamers
Status: COMPLETED
Conditions: Internet Gaming Disorder
Interventions: OTHER: active tDCS on the dlPFC|OTHER: sham tDCS on the dlPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole|PROCEDURE: Alveolar ridge preservation using autogenous demineralized dentin graft alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Knowledge of a "Non-return to Work" Predictive Score Influence Vocational Rehabilitation?
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Risk Score for non-return to work
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study to Test the Safety and How Radium-223 Dichloride an Alpha Particle-emitting Radioactive Agent Works in Combination With Pembrolizumab an Immune Checkpoint Inhibitor in Patients With Stage IV Non-small Cell Lung Cancer With Bone Metastases
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY 88-8223)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Find the Best Dose of HS-10384 to Treat Vasomotor Symptoms in Postmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Vasomotor Symptoms
Interventions: DRUG: HS-10384 tablet Dose 1|DRUG: HS-10384 tablet Dose 2|DRUG: HS-10384-matched placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics and Efficacy of KRN23 in Adult Chinese Patients With TIO
Status: COMPLETED
Conditions: Tumor-Induced Osteomalacia (TIO)
Interventions: DRUG: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Freeze All Protocol Versus Fresh Embryo Transfer in Women Undergoing In-vitro Fertilization (IVF)
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: Freeze-all protocol|PROCEDURE: Fresh transfer protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical BMT With Post-Transplant Cyclophosphamide and Bendamustine
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myelogenous Leukemia|Myelodysplastic Syndromes|Chronic Myelogenous Leukemia|Lymphoma,Non-Hodgkin|Lymphoma, Hodgkin|Lymphoma, Follicular|Marginal Zone Lymphoma|Large Cell Lymphoma|Mantle-Cell Lymphoma|Gray Zone Lymphoma|Burkitt Lymphoma|High Risk Undifferentiated Acute Leukemia
Interventions: DRUG: Bendamustine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aspiration and Sclerotherapy During Laparoscopy Using 95% Ethanol for the Treatment of Endometriomas
Status: UNKNOWN
Conditions: Endometrioma|Endometriosis
Interventions: PROCEDURE: Aspiration and Sclerotherapy of endometriomas.|PROCEDURE: cystectomy of endometriomas.|DRUG: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Setting up a Cohort of Patients With Crohn's Disease and a Cohort of Patients Without Chronic Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: PROCEDURE: biological samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Butyrate Supplementation in Children With Autism Spectrum Disorder (ASD) and Functional Gastrointestinal Disorders
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DIETARY_SUPPLEMENT: Sodium Butyrate|DIETARY_SUPPLEMENT: Placebo (cornstarch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Mixed Gliomas
Status: COMPLETED
Conditions: Mixed Gliomas
Interventions: DRUG: Atengenal|DRUG: Astugenal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Hypo- and Normo-thermic Perfusion to Preserve Extended Criteria Donor Livers for Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplantation
Interventions: DEVICE: Liver Machine Perfusion (MP) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DEVICE: suprapubic tube ex 2 day|DEVICE: suprapubic tube ex 5 day|DEVICE: transurethral catheter ex 5 day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Profile of Action of Drug in the Body of NN9535 in Healthy Male Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture Combined With Fast-track Perioperative Program for Laparoscopic Colorectal Surgery
Status: UNKNOWN
Conditions: Postoperative Ileus
Interventions: PROCEDURE: Electroacupuncture|OTHER: Fast-track Perioperative program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation to Lower Neuropathic Pain in People With Multiple Sclerosis
Status: TERMINATED
Conditions: Multiple Sclerosis|Neuropathic Pain
Interventions: DEVICE: Active tDCS using tDCS device|DEVICE: SHAM tDCS using tDCS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults
Status: RECRUITING
Conditions: Malaria
Interventions: DRUG: Pvs230D1-EPA/Matrix-M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Typical Versus Atypical Antipsychotics; Occupation of Striatal Receptors and the Appearance of Extrapyramidal Symptomatology, in Healthy Volunteers
Status: UNKNOWN
Conditions: Pharmacogenetics|Healthy
Interventions: DRUG: Risperidone|DRUG: Placebo|DRUG: Haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Influence of Intravenous Lidocaine on the Action of the Neuromuscular Blocker Rocuronium
Status: COMPLETED
Conditions: Neuromuscular Block
Interventions: DRUG: Placebo|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Solace Stress Urinary inContinence Control Efficacy and Safety Study
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Solace Bladder Control (Vesair) Balloon|DEVICE: Solace Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of TMV-018 in Patients With Tumors of the Gastrointestinal Tract
Status: WITHDRAWN
Conditions: Gastrointestinal Cancer
Interventions: BIOLOGICAL: TMV-018 + 5-FC|BIOLOGICAL: TMV-018 + anti-PD-1|BIOLOGICAL: TMV-018 + 5-FC + anti-PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ONCOFID-P-B (PACLITAXEL-HYALURONIC ACID)
Status: RECRUITING
Conditions: Bladder Carcinoma in Situ (CIS)
Interventions: DRUG: ONCOFID P-B (PACLITAXEL-HYALURONIC ACID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-BNOTA-PRGD2 PET/CT in Evaluation of Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: 68Ga-BNOTA-PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Zollinger-Ellison Syndrome With Prevacid
Status: COMPLETED
Conditions: Zollinger-Ellison Syndrome|Multiple Endocrine Neoplasia
Interventions: DRUG: Lansoprazole (Prevacid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AsthmaVent - Effect of Mechanical Ventilation on Asthma Control in Children
Status: COMPLETED
Conditions: Childhood Asthma|Allergy
Interventions: DEVICE: Ventilation|DEVICE: Placebo Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NBTXR3 With or Without Cetuximab in LA-HNSCC
Status: RECRUITING
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma|Aged
Interventions: DRUG: NBTXR3|DRUG: Cetuximab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing PEG-3350 (Miralax) and Gatorade With PEG-ELS (Golytely) for Bowel Preparation Prior to Colonoscopy
Status: UNKNOWN
Conditions: Bowel Preparation for Colonoscopy
Interventions: DRUG: PEG-ELS (Golytely)|DRUG: PEG-ELS (Golytely)|DRUG: Miralax mixed with Gatorade|DRUG: Miralax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of the Laryngeal Mask Airway (LMA) Supreme and I-gel in Children
Status: COMPLETED
Conditions: Laryngeal Masks in Children
Interventions: DEVICE: LMA Supreme: control device|DEVICE: i-gel: comparison device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Y-3 for Injection in the Treatment of Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Y-3 for injection|DRUG: Placebo control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Nutritional Supplement Intervention Among Hemodialysis Patients With Sarcopenic Obesity
Status: UNKNOWN
Conditions: Chronic Kidney Disease Requiring Chronic Dialysis|Sarcopenic Obesity|Body Composition
Interventions: DIETARY_SUPPLEMENT: ReGen 18%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Misoprostol Treatment of Mid Trimester Incomplete Abortion by Midwives and Doctors in Uganda.
Status: COMPLETED
Conditions: Incomplete Abortion
Interventions: OTHER: Misoprostol treatment by Midwife|OTHER: Misoprostol treatment by Doctor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exemestane and Celecoxib in Postmenopausal Women at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Exemestane|DIETARY_SUPPLEMENT: Calcium carbonate|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the 'SensPoint' Lactate Meter in the Estimation of Foetal Scalp Blood and Umbilical Cord Blood Lactate
Status: WITHDRAWN
Conditions: Measurement of Fetal Blood Lactate
Interventions: DEVICE: EKF Diagnostics 'SensPoint' Lactate Meter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety and Pharmacokinetic Study of Intravenous Clonidine Versus Midazolam for Sedation in Paediatric Patients
Status: TERMINATED
Conditions: Sedation in Intensive Care
Interventions: DRUG: Clonidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Novel Anti-caries Chewing Gum
Status: NOT_YET_RECRUITING
Conditions: Dental Plaque|Dental Caries|Periodontal Disease
Interventions: DIETARY_SUPPLEMENT: Gum base containing xylitol and essencial oils|DIETARY_SUPPLEMENT: Gum base with no additives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Pruritus With Intramuscular Promethazine
Status: COMPLETED
Conditions: Pruritus|Pregnancy Related
Interventions: DRUG: Promethazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy for Metastatic Melanoma Using CD8 Enriched Tumor Infiltrating Lymphocytes
Status: TERMINATED
Conditions: Skin Cancer|Metastatic Melanoma
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: IL-12 transduced TIL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Durvalumab|DRUG: Paclitaxel|DRUG: Capivasertib|DRUG: Anastrozole|DRUG: Fulvestrant|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Extension Study of Cannabidiol (GWP42003-P) in Children and Adults With Dravet or Lennox-Gastaut Syndromes
Status: COMPLETED
Conditions: Epilepsy|Dravet Syndrome|Lennox-Gastaut Syndrome
Interventions: DRUG: GWP42003-P
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vicriviroc on HIV Ribonucleic Acid (RNA) Levels in Cerebrospinal Fluid (Study P05241)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Vicriviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NGS-MRD Assessment of Combination Immunotherapies Targeting B-ALL
Status: RECRUITING
Conditions: B-Cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Antigen-specific T cells CART/CTL and DCvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Effectiveness of the BaroSense Articulating Circular Endoscopic (ACE) Stapler for Plication of Dilated Post-surgical Gastric Anatomy
Status: WITHDRAWN
Conditions: Obese
Interventions: PROCEDURE: BaroSense ACE Stapler for plication of dilated post-surgical gastric anatomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Mitochondrial Oxidative Stress in DCM
Status: RECRUITING
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: MitoQ Compound|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internal Iliac Artery Ligation Before Cesarean Hysterectomy in Morbidly Adherent Placenta
Status: COMPLETED
Conditions: Blood Loss
Interventions: PROCEDURE: Internal iliac artery ligation|PROCEDURE: cesarean hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prehospital Resuscitation Intra Nasal Cooling Effectiveness Survival Study
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: DEVICE: Prehospital intra-nasal cooling with RhinoChill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a High Protein, High Fiber Dietary Supplement on Weight and Fat Loss
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: High protein, high fiber dietary supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lung Surgery With Enhanced Recovery VS. Lung Surgery Without Enhanced Recovery
Status: RECRUITING
Conditions: Lung Cancer|Surgery|ERAS
Interventions: PROCEDURE: Enhanced Recovery After Surgery (ERAS )|PROCEDURE: Traditional perioperative management without Enhanced Recovery After Surgery (ERAS )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Metabolic Effects of Ghrelin in Skeletal Muscle and Adipose Tissue
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Acyl ghrelin|DRUG: Placebo (Ringer acetate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a 9-valent Human Papillomavirus Vaccine in HIV-positive Women
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections|HPV Infection
Interventions: BIOLOGICAL: Human Papillomavirus 9-valent Vaccine, Recombinant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Administration of Magnesium Sulfate in Hysterectomy Cases
Status: COMPLETED
Conditions: Abdominal Hysterectomy|General Anesthesia|Magnesium Sulfate
Interventions: DRUG: magnesium sulfate group|DRUG: control group saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Probiotics and Influenza Vaccination Response
Status: COMPLETED
Conditions: Vaccine Response
Interventions: DIETARY_SUPPLEMENT: Probiotic effect on influenza vaccine response
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Determination of the RANKL/Osteoprotegerin Ratio in Patients With Systemic Lupus Erythematosus. Role in Osteoporosis and Cardiovascular Calcification
Status: COMPLETED
Conditions: Osteoporosis|Lupus Erythematosus, Systemic
Interventions: BIOLOGICAL: RANKL/OPG ratio|DEVICE: bone densitometry|DEVICE: fan beam CT scan|DEVICE: Doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Nasal Spray Solution Containing Human IgG1 Anti-COVID-19 Antibody Cocktail
Status: COMPLETED
Conditions: SARS CoV 2 Infection|SARS-CoV-2 Acute Respiratory Disease
Interventions: DEVICE: Human IgG1 anti-SARS-CoV-2 antibody cocktail|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NeoSAMBA: Neoadjuvant: Does the Sequence of Anthracycline and Taxane Matters: Before or After?
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: FAC x 3 followed by Docetaxel x 3|DRUG: Docetaxel x 3 followed by FAC x 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Nerve Block for Hip Fracture Pain Management at Emergency Department
Status: UNKNOWN
Conditions: Hip Fractures|Pain, Acute|Ultrasound Therapy; Complications
Interventions: PROCEDURE: Ultrasound guided Suprainguinal Iliac Fascia Nerve Block.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Cadonilimab Plus Chemotherapy for Locally Advanced Esophagogastric Junction and Gastric Cancer Trial
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Esophagogastric Junction Cancer
Interventions: DRUG: Cadonilimab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil to Reduce Persistent Fatigue in Patients Following Treatment for Cancer
Status: COMPLETED
Conditions: Cancer|Fatigue|Chemotherapy
Interventions: DRUG: Modafinil|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Metamin 3D on the Lipid and Glucose in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Metamin 3D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Multicenter, Non-randomized, Single Arm Clinical Trial to Evaluate the Safety and Efficacy of e-PTFE Grafts Inner Surface-treated With Paclitaxel as an Access for Hemodialysis in Patients With End-stage Renal Disease.
Status: UNKNOWN
Conditions: Hemodialysis Access Failure
Interventions: DEVICE: Paclitaxel-eluting graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy
Status: COMPLETED
Conditions: Sudden Cardiac Death|Heart Failure
Interventions: OTHER: Educational Video1|OTHER: Educational Video 2|OTHER: Usual Care 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE