pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ABEMA Alone or in COMBO With MK-6482
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: MK-6482
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rifamycin SV-MMX® 400 mg b.i.d. vs. Rifamycin SV-MMX® 600 mg t.i.d. vs. Placebo in Acute Uncomplicated Diverticulitis
Status: COMPLETED
Conditions: Uncomplicated Diverticulitis
Interventions: DRUG: Rifamycin SV-MMX® 400 mg b.i.d.|DRUG: Rifamycin SV-MMX® 600 mg t.i.d.|DRUG: Rifamycin SV-MMX® Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytomegalovirus (CMV) Reactivation in Allogeneic HSCT Recipient
Status: ENROLLING_BY_INVITATION
Conditions: Cytomegalovirus Infections|Haematological Malignancy|Organ or Tissue Transplant; Complications|Immune Suppression
Interventions: DIAGNOSTIC_TEST: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis
Status: UNKNOWN
Conditions: Renal Failure|Bacterial Infections|Critical Illness
Interventions: DRUG: Ceftazidime-avibactam
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lowering Serum Uric Acid to Prevent Acute Kidney Injury
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DRUG: Rasburicase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Bacopa Monnieri and Nardostachys Jatamansi to Treat Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Bacopa monnieri|DRUG: Nardostachys jatamansi|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Effect of Screening Using Imaging (CT/ EUS) on Early Detection of Pancreatic Ductal Adenocarcinoma (PDAC) in Patients With New Onset Diabetes (NOD)" - A Prospective Pilot Observational Study
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: PROCEDURE: A blood sample for CA 19-9 (cancer detection test)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Tension Free Primary Closure, Karydaks and Limberg Flap Methods
Status: COMPLETED
Conditions: Pilonidal Disease|Recurrence|Complication
Interventions: PROCEDURE: tension free primary closure|PROCEDURE: karydakis|PROCEDURE: Limberg flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity
Status: UNKNOWN
Conditions: Neurotoxicity|Gastrointestinal Neoplasms
Interventions: OTHER: electro-acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bone Marrow Derived Autologous Cells Treatment of Cerebral Palsy in Subjects Above 15 Years
Status: UNKNOWN
Conditions: Ataxic Infantile Cerebral Palsy
Interventions: BIOLOGICAL: stem cell (MNCs )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Stress Management for People With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Coping skills training|BEHAVIORAL: Written emotional disclosure|BEHAVIORAL: Arthritis education|BEHAVIORAL: Health behavior writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose:
Clinical trial: Long-acting G-CSF for Febrile Neutropenia
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer|Colony Stimulating Factors|Febrile Neutropenia|Myelosuppression Adult|Adverse Event|Cost-effectiveness
Interventions: DRUG: long-acting granulocyte colony stimulating factor|DRUG: Short-term granulocyte colony stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Combination Chemotherapy In Treating Patients With Limited Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial of a Topical Anesthetic to Evaluate Pain and Anxiety During Venipuncture
Status: COMPLETED
Conditions: Pain|Anxiety
Interventions: DRUG: 4% lidocaine topical anesthetic cream|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of AZD7762 in Combination With Gemcitabine
Status: TERMINATED
Conditions: Cancer|Solid Tumors|Advanced Solid Malignancies
Interventions: DRUG: AZD7762|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Tolerability of AZD2171 After Multiple Doses in Patients With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Advanced Prostate Adenocarcinoma
Interventions: DRUG: AZD2171
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet Composition and Physical Inactivity on Insulin Sensitivity and β-cell Function
Status: COMPLETED
Conditions: Physical Inactivity|Dietary Protein
Interventions: BEHAVIORAL: normal protein diet|BEHAVIORAL: high protein intake
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Bioactive Glass-ceramic Intervertebral Spacer (Bonglass-SS) in Posterior Lumbar Interbody Fusion
Status: UNKNOWN
Conditions: Degenerative Disk Disease
Interventions: DEVICE: 4 CIS one-touch titanium cage|DEVICE: Bonglass-SS SSLPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of AUY922 in Non-small-cell Lung Cancer Patients Who Have Received Previous Two Lines of Chemotherapy.
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: AUY922
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: UVA Brain and Aortic Aneurysm Study
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Abdominal Aortic Aneurysm
Interventions: OTHER: Imaging-Ultrasound|OTHER: Imaging-MRA|GENETIC: DNA, RNA testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of NGM282 in Patients With Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis
Interventions: BIOLOGICAL: NGM282|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia
Status: COMPLETED
Conditions: Postoperative Nausea
Interventions: DRUG: Fosaprepitant 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mild vs Moderate Hypothermic Circulatory Arrest With Unilateral Anterograde Cerebral Perfusion in Hemiarch Replacement
Status: COMPLETED
Conditions: Aortic Aneurysm
Interventions: PROCEDURE: Hypothermic circulatory arrest with unilateral selective anterograde cerebral perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Acupuncture for Treatment of Chemotherapy-induced Peripheral Neuropathy (CIPN).
Status: COMPLETED
Conditions: Neoplasm|Adult Disease|Neuropathy
Interventions: PROCEDURE: Acupuncture|BEHAVIORAL: Orientation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Aminobiphosphonates and Statins on Circulating Vgamma9Vdelta2-T Cells
Status: COMPLETED
Conditions: Bone Metastases of a Malignant Tumor
Interventions: DRUG: Aminobiphosphonate|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Antioxidant Status in Chronic Hepatitis C Patients Before and After Antioxidant Supplementation: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Hepatitis C|Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Antioxidant Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PINNACLE® DM RSA Study
Status: TERMINATED
Conditions: Osteoarthritis|Degenerative Arthritis|Revision Arthroplasty
Interventions: DEVICE: Total Hip Arthroplasty|DEVICE: Revision Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Culturally Adapted Psychological Intervention for the Management of Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Culturally adapted Cognitive Behavior Therapy for IBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Anti-microbial Spray Dressing in Preventing Tenckhoff Catheter Exit Site Infection for End Stage Renal Failure Patients
Status: UNKNOWN
Conditions: Signs and Symptoms of Exit Site Infection|Physical Damage of the Tenckhoff Catheter|Skin Allery
Interventions: OTHER: JUC spray dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients
Status: COMPLETED
Conditions: Multidrug-resistant Tuberculosis|Extensively Drug-resistant Tuberculosis
Interventions: DRUG: Addition of different doses of clarithromycin.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Cisplatin, and Amifostine in Treating Patients With Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Drug/Agent Toxicity by Tissue/Organ|Lung Cancer
Interventions: DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorders
Status: COMPLETED
Conditions: Macular Degeneration|Retinal Vein Occlusion|Diabetic Retinopathy
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Islet Allotransplantation With Steroid Free Immunosuppression
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia|Metabolic Diseases
Interventions: PROCEDURE: islet transplantation|DRUG: daclizumab - sirolimus - tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elacytarabine Mass Balance Study in Healthy Volunteers
Status: COMPLETED
Conditions: Not Applicable as This is a Mass Balance/Pharmacokinetic Study Performed in Healthy Subjects
Interventions: DRUG: [14C]-Elacytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Allogenic Bone Marrow Stem Cells Transplantation in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: PROCEDURE: Allogenic bone marrow stem cells transplantation|DRUG: Conserved therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Roflumilast in Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: 0.5% Roflumilast Cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Mitoxantrone Hydrochloride Liposome Injection Combined With Capecitabine Versus Capecitabine Monotherapy in Patients With Recurrent Metastatic Nasopharyngeal Carcinoma Who Failed Platinum-containing Treatment
Status: NOT_YET_RECRUITING
Conditions: Recurrent Metastatic Nasopharyngeal Carcinoma
Interventions: DRUG: Mitoxantrone hydrochloride liposome injection|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Anesthesia for Uterine Curettage
Status: COMPLETED
Conditions: Uterine Curettage|Abortion, Induced
Interventions: DRUG: Lidocaine|DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Between Two 1% Clindamycin/5% Benzoyl Peroxide Topical Gel Formulations
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: 1% Clindamycin/5% Benzoyl Peroxide Topical Gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in People With Idiopathic CD4 T Cell Lymphocytopenia
Status: RECRUITING
Conditions: Idiopathic CD4 T Cell Lymphocytopenia
Interventions: BIOLOGICAL: Gardasil 9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcricoid Injection vs. Spray as You go Method for Local Anaesthesia During EBUS-TBNA
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: DRUG: Transcricoid Injection|DRUG: Spray as you go
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Tolerability of AP 12009, Administered I.V. in Patients With Advanced Tumors Known to Overproduce TGF-beta-2
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Melanoma|Colorectal Neoplasms
Interventions: DRUG: AP 12009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.
Status: COMPLETED
Conditions: Heart Transplant Recipients
Interventions: PROCEDURE: OCT and coronary angiography|PROCEDURE: Right heart cat.|RADIATION: PET|PROCEDURE: Echocardiography|PROCEDURE: exercise test|OTHER: blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Allogeneic Hematopoietic Stem Cell Transplantation With Reduced Intensity Pre-transplant Conditioning for the Treatment of High-risk Hematological Malignancies (V3)
Status: TERMINATED
Conditions: Hematological Malignancies
Interventions: DRUG: Regimen A|DRUG: Regimen B|DRUG: Regimen C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De Novo Everolimus-based Therapy for Renal Transplantation Using Rituximab Induction
Status: TERMINATED
Conditions: Renal Insufficiency
Interventions: DRUG: rituximab and everolimus|DRUG: thymoglobulin and tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of Human Growth Hormone (hGH) vs Placebo in Intensively Treated Haemato-Oncology Patients.
Status: COMPLETED
Conditions: Multiple Myeloma|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Human Growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Diabetes Exercise and Lifestyle Trial
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: High volume combined aerobic/resistance exercise|BEHAVIORAL: Low volume combined aerobic/resistance exercise|BEHAVIORAL: High volume combined A/R exercise, printouts, pedometers|BEHAVIORAL: Low volume combined A/R exercise, printouts, pedometers|BEHAVIORAL: Printed PA information, pedometers and step log group|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer|Oropharyngeal Cancer|Hypopharyngeal Cancer|Upper Aerodigestive Tract Neoplasms
Interventions: PROCEDURE: da Vinci® Robotic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethacrynic Acid Elimination in Non-Muscle Invasive Bladder Cancer Patients Undergoing Transurethral Resection
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Ethacrynic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Determine the Safety of Regorafenib, Hydroxychloroquine, and Entinostat Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: hydroxychloroquine|DRUG: entinostat|DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zinc and Biobehavioral Development in Early Childhood
Status: COMPLETED
Conditions: Child Development
Interventions: DIETARY_SUPPLEMENT: zinc|DIETARY_SUPPLEMENT: iron + copper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Stereotactic Body Radiotherapy With Concurrent Pembrolizumab in Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Metastatic Urothelial Cancer
Interventions: DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Renin treatment-guided Therapeutics|OTHER: Referral Hypertension specialist|DRUG: Aldosterone Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure (IOP) Lowering Efficacy of Transdermal Latanoprost Therapy
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: 0.005% Latanoprost dosed once.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIFE - Lung Cancer, Immunotherapy, Frailty, Effect
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer|Quality of Life|Brain Metastases|Venous Thromboembolism
Interventions: DIAGNOSTIC_TEST: CT-scans extended|DIAGNOSTIC_TEST: MRI scan of the brain|OTHER: Prospective registration of irAEs|BEHAVIORAL: Quality of Life questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dry Needling on Muscle Function in Patients With Hip Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: OTHER: Dry needling|OTHER: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal Bleeding
Status: RECRUITING
Conditions: Cirrhosis, Liver|Hypertension, Portal|Variceal Hemorrhage
Interventions: OTHER: No use of prophylactic antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Fusion With Porous Versus Non-Porous Cages
Status: RECRUITING
Conditions: Spinal Fusion|Lumbar Fusion|Arthrodesis|Spondylolisthesis|Pseudarthrosis
Interventions: DEVICE: CONDUIT Porous Titanium Spinal Cage|DEVICE: PROTI 360 Titanium-Coated PEEK Spinal Cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study of Pyrotinib in Patients With HER2 Positive Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Neoplasm, Breast|Breast Diseases
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study of OPT-302 With Aflibercept for Persistent Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: BIOLOGICAL: Aflibercept|BIOLOGICAL: OPT-302|OTHER: Sham intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of Gabapentin for Post-operative Pain After Cesarean Section
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Gabapentin|OTHER: lactose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Phase II Study of Ixabepilone Alone and Ixabepilone Plus Cetuximab as First-Line Treatment for Female Subjects With Triple Negative Locally Advanced Non-resectable and/or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Locally Advanced Non-resectable Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: ixabepilone|DRUG: ixabepilone + cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Step Up For Health Study: A Pedometer and Website Intervention in Those With Prediabetes
Status: TERMINATED
Conditions: Prediabetes|Impaired Glucose Tolerance
Interventions: BEHAVIORAL: Website intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Open Label, 4 Week Study of ITCA 650 in Adults With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ITCA 650 (exenatide in DUROS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Basic-clinical Translational Research in Hepatitis B Virus (HBV)-Specific Antigen Peptides and HepG2 Cell Lysate Co-activated Dendritic Cells Combined With Transarterial Chemoembolization (TACE) in HBV-related HCC Treatment (BTRHBVAPHCLCDCCTCHBVHCCT)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: ADCC & TACE|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zidovudine Plus Interleukin-2 and Ganciclovir in Treating Patients With AIDS-Related Primary Central Nervous System Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: aldesleukin|DRUG: ganciclovir|DRUG: zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between Foraseq And Formoterol/Budesonide Inhalation Capsules in Patients With Asthma
Status: COMPLETED
Conditions: ASTHMA
Interventions: DRUG: Formoterol/Budesonide|DRUG: Foraseq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanolic Extract of Aloe Vera Versus Chlorohexidine as Cavity Disinfectant.
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: Ethanolic extract of Aloe vera gel cavity disinfectant|OTHER: Chlorohexadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures
Status: RECRUITING
Conditions: HIV Infections
Interventions: DRUG: VOCABRIA 30Mg Tablet|DRUG: EDURANT 25Mg Tablet|DRUG: Cabotegravir Injectable Suspension|DRUG: Rilpivirine Injectable Suspension|BIOLOGICAL: Intact proviral DNA assay|BIOLOGICAL: Full-length sequencing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Understand the Effect of Low-Fat and High-Fat Meals on the Medicine Called PF-07284890 in Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-07284890 Treatment A|DRUG: PF-07284890 Treatment B|DRUG: PF-07284890 Treatment C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Nutrition Counselling on Old Age People's Nutritional Status and Quality of Life in Bahir Dar City, North West Ethiopia
Status: UNKNOWN
Conditions: Malnutrition|Quality of Life
Interventions: BEHAVIORAL: Nutritional counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Efficacy of Dexloxiglumide for the Relief of Symptoms of Functional Dyspepsia.
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: dexloxiglumide|DRUG: Nexium (esomeprazole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Reactogenicity and Immunogenicity of the repRNA(QTP104) Vaccine Against SARS-CoV-2(COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|SARS-CoV-2
Interventions: BIOLOGICAL: QTP104 1ug|BIOLOGICAL: QTP104 5ug|BIOLOGICAL: QTP104 25ug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Telerehabilitation of Balance Clinical and Economic Decision Support System
Status: NOT_YET_RECRUITING
Conditions: Stroke|Mild Cognitive Impairment|Vestibular Diseases|Long Covid19
Interventions: DEVICE: Full/High Tech Telerehabilitation decision support system|DEVICE: Basic/Low Tech Telerehabilitation decision support system|PROCEDURE: OTAGO Home exercise program|PROCEDURE: Vestibular rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voice and Swallow Outcomes After Office-based Injection Laryngoplasty in Patients With Glottal Insufficiency
Status: NOT_YET_RECRUITING
Conditions: Voice and Swallow Outcomes After Injection Laryngoplasty in Patients With Glottal Insufficiency
Interventions: DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methadone for 'Adenocarcinopathic' Pain Treatment
Status: WITHDRAWN
Conditions: Cancer Pain|Adenocarcinoma
Interventions: DRUG: Methadone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Molecular, Histologic, and Clinical Analysis of Negative Pressure Wound Therapy (NPWT) for Split-thickness Skin Graft (STSG) Donor Sites
Status: WITHDRAWN
Conditions: Split-thickness Skin Graft Donor Sites|Burns
Interventions: DEVICE: Modified NPWT dressing|DEVICE: Tegaderm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Trial of Adjuvant Oral Glucocorticoid Pulse Therapy in Pemphigus
Status: COMPLETED
Conditions: Pemphigus
Interventions: DRUG: dexamethasone (50mg 1dd6, 3 consecutive days/month)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: SKB264|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Capecitabine|DRUG: Eribulin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine For Neuroprotection During Cardiac Surgery
Status: COMPLETED
Conditions: Cognitive Decline
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Status: COMPLETED
Conditions: Pediatric Obesity|Lower Extremity Biomechanics
Interventions: OTHER: Strength and neuromuscular exercise programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, and Effects of CHI-202 to Support Recovery From Physical Activity
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness (DOMS)
Interventions: DIETARY_SUPPLEMENT: CHI-202|DIETARY_SUPPLEMENT: CHI-101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Immunogenicity and Safety of Quadrivalent Influenza Vaccine in Children and Adolescents
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: NBP607-QIV|BIOLOGICAL: Agrippal S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamics Of Satralizumab In Patients With Anti-N-Methyl-D-Aspartic Acid Receptor (NMDAR) Or Anti-Leucine-Rich Glioma-Inactivated 1 (LGI1) Encephalitis
Status: RECRUITING
Conditions: NMDAR Autoimmune Encephalitis|LGI1 Autoimmune Encephalitis
Interventions: DRUG: Satralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PneuMum: Pneumococcal Vaccination of Australian Indigenous Mothers
Status: COMPLETED
Conditions: Middle Ear Effusion|Tympanic Membrane Perforation|Acute Otitis Media|Pneumococcal Infections
Interventions: BIOLOGICAL: 23vPPV, dTpa (Pneumovax, Boostrix)|BIOLOGICAL: 23vPPV, dTpa (Pneumovax, Boostrix)|BIOLOGICAL: 23vPPV, dTpa (Pneumovax, Boostrix)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A (M)Ulti-center, Prospective, (O)Pen Label, Uncontrolled Feasibility (S)Tudy to Assess the Safety and Effectiveness of an Automatic Low Flow (A)Scites (Alfa) Pump (I)n Patients With (C)Irrhosis and Refractory or Recurrent Ascites
Status: COMPLETED
Conditions: Cirrhosis|Ascites
Interventions: DEVICE: alfapump system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esmolol Pretreatment on Pain During Injection of Propofol
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Normal saline|DRUG: Esmolol|DRUG: Remifentanil|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ultra-Sound Guided Pre-emptive Nerve Block on Post-operative Pain Following Open Inguinal Hernia Repair.
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Ultra sound guided nerve block|PROCEDURE: Usual infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Human Albumin Infusion on VEGF Levels in Women at Risk for Ovarian Hyperstimulation Syndrome
Status: WITHDRAWN
Conditions: Ovarian Hyperstimulation Syndrome
Interventions: DRUG: Human Albumin Infusion|DRUG: Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Study of Pharmacokinetic-Guided Docetaxel in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide
Status: COMPLETED
Conditions: Breast Cancer|Breast Cancer Female
Interventions: DRUG: Standard of Care: Docetaxel|DRUG: Standard of Care: Cyclophosphamide|OTHER: Function Assessment of Cancer Therapy (FACT) Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUSTAIN - Study of Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Age Related Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of BI 1810631 in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1810631|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HIV-1 Rgp-160 Administered by Mucosal Routes in Healthy Volunteers
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 gp 160|BIOLOGICAL: DC-Chol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adipose-derived Stem Cells (ADSCs) for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Elixcyte 8 ml|DEVICE: Hya Joint Plus|BIOLOGICAL: Elixcyte 4 ml|BIOLOGICAL: Elixcyte 2 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Home-based Aromatherapy for BPSD
Status: COMPLETED
Conditions: Behavioural and Psychiatric Symptoms of Dementia
Interventions: OTHER: Home-based aromatherapy programme|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer
Status: RECRUITING
Conditions: Recurrent Endometrial Carcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: Anastrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Adjuvant Effect of Shock Wave Therapy in the Insertional Achilles Tendinopathy
Status: COMPLETED
Conditions: Achilles Tendinitis|Tendinopathy
Interventions: DEVICE: Shock Wave Therapy|OTHER: Eccentric Exercises|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol
Status: COMPLETED
Conditions: Gout|Hyperuricemia|Arthritis|Joint Disease
Interventions: DRUG: ulodesine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aventus Thrombectomy System Pulmonary Embolism Clinical Study
Status: RECRUITING
Conditions: Pulmonary Embolism|Embolism|Embolism and Thrombosis|Vascular Diseases|Cardiovascular Diseases|Lung Diseases|Respiratory Tract Diseases
Interventions: DEVICE: Thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Monitoring of Patients Receiving CDK 4/6 Inhibitors for Hormone Receptor (HR) Positive, HER2 Negative Metastatic Breast Cancer (MBC) With or Without the Addition of DiviTum® Serum Thymidine Kinase 1 (TK1) Activity Testing
Status: RECRUITING
Conditions: Breast Cancer|Cancer of the Breast
Interventions: DEVICE: DiviTum® TKa assay|OTHER: Study Care Plans
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of ANX005 in Subjects With Guillain-Barré Syndrome
Status: RECRUITING
Conditions: Guillain-Barre Syndrome
Interventions: DRUG: ANX005|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label, Dose Escalation Phase I Study of AZD2281
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: KU-0059436 (AZD2281)(PARP inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot "Window-3" Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Rituximab|OTHER: Brexucabtagene Autoleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19: Healthy Oregon (Oregon Saludable): Together We Can (Juntos Podemos)
Status: COMPLETED
Conditions: Health Behavior|Health Care Utilization
Interventions: BEHAVIORAL: Promotores de Salud|BEHAVIORAL: Services as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Three Hepatitis B Vaccination Regimens in HIV-Positive Youth
Status: COMPLETED
Conditions: HIV Infection|Hepatitis B
Interventions: BIOLOGICAL: Engerix-B 20 mcg|BIOLOGICAL: Engerix-B 40 mcg|BIOLOGICAL: Twinrix 720 EIA HAV Ag plus 20 mcg HBsAg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: PROCEDURE: Implant Procedure|DRUG: Conventional Synthetic DMARD|DEVICE: Active stimulation|DEVICE: Non-active stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti TNFa Upon Deep Endometriosis Associated Pain
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: anti TNFa monoclonal antibody - Infliximab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: REL-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the Hygiene Rules
Status: RECRUITING
Conditions: Xerostomia
Interventions: DEVICE: sialendoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of ChatGPT in Vestibular Schwannoma Management
Status: NOT_YET_RECRUITING
Conditions: Vestibular Schwannoma
Interventions: BEHAVIORAL: Use of chatGPT for 1 week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupivacaine
Status: COMPLETED
Conditions: Male Infertility
Interventions: DRUG: Liposomal Bupivacaine|DRUG: Standard Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Active Tuberculosis Using Ultra Low-dose Chest CT
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary|Latent Tuberculosis
Interventions: RADIATION: Ultra low dose chest computed tomography (ULDCT)|RADIATION: Chest X-ray|DIAGNOSTIC_TEST: Interferon-gamma Release Assay (IGRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Temperature and Healing in Treatment of Gingival Enlargement
Status: COMPLETED
Conditions: Gingival Enlargement
Interventions: PROCEDURE: Er:YAG LASER, Nd:YAG laser, elctrosurgery, conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Vytorin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Androgen Priming Before COS Using Aromatase Inhibitor and hCG During Early-Follicular-Phase GnRH Antagonist Administration - a Randomized Controlled Trial
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Downregulation and androgen priming by use of GnRH antagonist, aromatase inhibitor and hCG before COH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Harmonics-based in Vivo Optical Virtual Biopsy
Status: RECRUITING
Conditions: Healthy Participants With Different Skin Types and Different Ages|Diseased Participants With Different Skin Types and Different Ages|Participants Suffered From Diabetes With Different Skin Types and Different Ages
Interventions: DEVICE: Harmonic Generation Microscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Coral Bone Graft Verses Xenograft With Immediate Implant in Maxillary Anterior Esthetic Zone
Status: TERMINATED
Conditions: Badly Decayed Anterior Maxillary Teeth
Interventions: DEVICE: coral bone graft and xenograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lu AF35700 in Patients With Early-in-disease or Late-in-disease Treatment-resistant Schizophrenia
Status: TERMINATED
Conditions: Treatment-resistant Schizophrenia
Interventions: DRUG: Lu AF35700|DRUG: Risperidone|DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tooth Wear:m Tooth Wear : Diagnosis- Treatment Decision
Status: UNKNOWN
Conditions: Dental Wear
Interventions: DEVICE: Clearfil Majesty TM|DEVICE: Vita-Enamic®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT