pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Status: UNKNOWN
Conditions: Complex Regional Pain Syndromes|Fibromyalgia|Stroke|Traumatic Brain Injury|Osteoarthritis|Back Pain|Sciatica
Interventions: DEVICE: Virtual Environment Biofeedback|DEVICE: Treadmill walking with no Virtual Environment Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Magnesium and Ketorolac in Ultrasound Supraclavicular Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Magnesium sulfate|DRUG: Ketorolac Tromethamine|PROCEDURE: supraclavicular block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the in Use Tolerance of E45 Eczema Repair Emollient in Babies and Children With (Very(Dry/Atopic Skin
Status: COMPLETED
Conditions: Atopic Dermatitis / Eczema
Interventions: DEVICE: E45 Eczema Repair Emollient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Coronary Artery Calcification Using Gated Stationary Chest Tomosynthesis
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Gated Stationary Chest Tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients
Status: ENROLLING_BY_INVITATION
Conditions: Botulism
Interventions: BIOLOGICAL: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Continuous Non-invasive Blood Pressure Monitoring on Hypotension in Patients Having Non-cardiac Surgery
Status: COMPLETED
Conditions: Blood Pressure|Perioperative Hypotension
Interventions: DEVICE: Continuous non-invasive blood pressure monitoring|DEVICE: Intermittent non-invasive blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: High Flux Hemodialysis Thrice Versus Once
Status: UNKNOWN
Conditions: End-Stage Renal Disease
Interventions: DEVICE: high flux hemodialyzer (FX-60, FX-80 or FX-100)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia|Refractive Errors|Eye Diseases
Interventions: DEVICE: Novel LEDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vasopressin for Septic Shock Pragmatic Trial
Status: ENROLLING_BY_INVITATION
Conditions: Septic Shock
Interventions: DRUG: Vasopressin|OTHER: Recommendation to use a lower initiation threshold for vasopressin|OTHER: Recommendation to use a higher initiation threshold for vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracyclines
Status: RECRUITING
Conditions: Cardiotoxicity
Interventions: DRUG: Empagliflozin 10 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT Tumors
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: PROCEDURE: Metastases Resection ( multiple steep surgery possible)|DRUG: 5-Fluorouracile|DRUG: leucovorin L|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploration of Dalpiciclib + Tucidinostat in HR+/HER2- Advanced Breast Cancer After Failure of CDK4/6 Inhibitor
Status: NOT_YET_RECRUITING
Conditions: HR+/HER2- Advanced Breast Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Tucidinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Digital Health Program for Non-Communicable Disease Prevention in a Workplace Setting in Thailand
Status: NOT_YET_RECRUITING
Conditions: Chronic Disease|Noncommunicable Diseases
Interventions: BEHAVIORAL: A Digital Health Program for Non-Communicable Disease Prevention in a Workplace Setting in Thailand
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation
Status: COMPLETED
Conditions: Procedural Sedation
Interventions: DRUG: Propofol|DRUG: 1:1 Propofol/Ketamine|DRUG: 4:1 Propofol/Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pathophysiology of Gas Exchange and Time Course Changes in Spontaneously Breathing Patients With Acute Respiratory Failure Due to COVID-19. A Multicenter Prospective Study.
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: OTHER: Pathophysiology of gas exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pulsed Low Dose Rate Radiation Therapy for Gastric Cancer Patients With Peritoneal Metastasis
Status: UNKNOWN
Conditions: Radiotherapy|Radiotherapy Side Effect|Stomach Neoplasms
Interventions: RADIATION: pulsed low dose rate radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes After Dry Needling on Cervical Muscles, and Quality of Life, in Patients With Fibromyalgia Syndrome.
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Dry Needling Therapy|OTHER: Myofascial Release Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atomoxetine/Attention Deficit/ Hyperactive Disorder (ADHD)/Substance Use Disorder (SUD)in a Residential Treatment Facility
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers for Early Detection of Lung Cancer in Patients With Lung Cancer, Participants at High-Risk for Developing Lung Cancer, or Healthy Volunteers
Status: UNKNOWN
Conditions: Lung Cancer|Tobacco Use Disorder
Interventions: OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: sputum cytology|PROCEDURE: Fourier transform infrared spectroscopy|PROCEDURE: diagnostic bronchoscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Trial (RCT) of a Motivational Decision Support System
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Web-based motivational decision support system|BEHAVIORAL: NCI Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ketorolac|DRUG: Bupivacaine|DRUG: ketorolac + bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Addition of Uterosacral Ligament Plication to Pectopexy Operation on Anatomical and Subjective Symptoms
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: pectopexy operation|PROCEDURE: uterosacral ligaments plication operation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fetal Brain Care: Therapies for Brain Neurodevelopment in Fetal Growth Restriction
Status: RECRUITING
Conditions: Fetal Growth Retardation|Intrauterine Growth Restriction
Interventions: DIETARY_SUPPLEMENT: Lactoferrin and DHA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Promoting Women's Health: A Gender Specific Smoking Cessation Program for Female Smokers in Hong Kong
Status: RECRUITING
Conditions: Smoking Cessation
Interventions: DRUG: nicotine gum or nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Food Choices in Healthy Weight Women
Status: COMPLETED
Conditions: Addictive Behavior|Food Preferences|Food Habits|Healthy|Habituation
Interventions: OTHER: CAKE|OTHER: APRICOTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gatifloxacin|DRUG: Moxifloxacin|DRUG: Besifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: ZD4054 (Zibotentan) or Placebo Plus Chemotherapy in Patients With Advanced Ovarian Cancer
Status: TERMINATED
Conditions: Patients With Advanced Ovarian Cancer Sensitive to Platinum-based Chemotherapy
Interventions: DRUG: ZD4054 Zibotentan|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of the Distribution of Nitrate Reducing Bacteria in the Human Oral Cavity
Status: UNKNOWN
Conditions: No Dental Disease|Non-smoking
Interventions: OTHER: beetroot Juice|OTHER: Buxton water|OTHER: antiseptic mouthwash then beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sustained Lung Inflation in Preterm Infants
Status: COMPLETED
Conditions: Preterm Infant
Interventions: PROCEDURE: Sustained lung inflation (SLI)|PROCEDURE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: LIBERTY: Liquid Biopsy to Diagnose and Monitor CNS Involvement in High-risk B Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non-hodgkin Lymphoma, B Cell
Interventions: DIAGNOSTIC_TEST: ctDNA detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches
Status: ENROLLING_BY_INVITATION
Conditions: Blood Culture Rates|Antibiotic Stewardship|Implementation Science
Interventions: BEHAVIORAL: Checklist|BEHAVIORAL: Targeted Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: The Clotting Effects of Pentastarch and Normal Saline in Obstetric Patients
Status: COMPLETED
Conditions: Elective Cesarean Section
Interventions: DRUG: Pentaspan®|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of CyberKnife Stereotactic Radiosurgery to Prostate Tumors
Status: UNKNOWN
Conditions: Prostate Cancer|Cancer of the Prostate|Prostate Neoplasm
Interventions: RADIATION: CyberKnife Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology
Status: RECRUITING
Conditions: Astrocytoma|Ependymoma|Ganglioglioma|Oligodendroglioma|Optic Nerve Glioma|Meningioma|Nerve Sheath Neoplasms|Adenoma|Craniopharyngioma|Hemangiopericytoma|Germinoma|Neurilemmoma
Interventions: OTHER: ProTRAIT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Participation (Within USA) Trial of Sana Pain Reliever
Status: COMPLETED
Conditions: Neuropathic Pain|Chronic Pain|Pain
Interventions: DEVICE: Sana Pain Reliever|DEVICE: Sham SPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effectiveness and Safety of Carrelizumab Combined With Apatinib Mesylate and Radiotherapy in the Treatment of Advanced Liver Cancer
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Camrelizumab Apatinib Mesylas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Use of Oxycodone During the Acute Phase of Herpes Zoster on Preventing Postherpetic Neuralgia
Status: UNKNOWN
Conditions: Herpes Zoster|Post-herpetic Neuralgia
Interventions: DRUG: Oxycodone|DRUG: Gabapentin|DRUG: Famciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remimazolam vs Midazolam Cognitive and Motor Recovery After Intravenous Conscious Sedation for Dental Extractions.
Status: RECRUITING
Conditions: Tooth Extraction
Interventions: DRUG: Remimazolam|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient and Observer Reported Outcome Measurements in Inborn Errors of Metabolism
Status: COMPLETED
Conditions: Inborn Errors of Metabolism|Urea Cycle Disorder|Maple Syrup Urine Disease|Phenylketonurias|Methylmalonicacidemia|OTC Deficiency|Aminoacidopathy|Patient Reported Outcome Measurements
Interventions: OTHER: Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gait Analysis of a Lateral-Pivot Design Total Knee Replacement
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DEVICE: DJO Empowr PS Knee System|DEVICE: Stryker Triathlon Total Knee System|DEVICE: Biomet Vanguard Complete Knee System|DEVICE: Control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition
Status: WITHDRAWN
Conditions: Diarrhea, Malnutrition|Other Nutritional Deficiencies
Interventions: DRUG: Alanyl-glutamine|DRUG: Glycine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Improved "Injera" Baking Stove Use on Childhood Acute Respiratory Infection Prevention in Northwest Ethiopia
Status: UNKNOWN
Conditions: Acute Respiratory Infection|Pneumonia Childhood
Interventions: DEVICE: Improved "Injera" Baking Biomass Stove
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Remdesivir|DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Shockwave Treatment for Proximal Fifth Metatarsal Stress Fracture in Soccer Players
Status: COMPLETED
Conditions: Stress Fracture Metatarsal
Interventions: PROCEDURE: Intramedullary screw fixation|DEVICE: Focused Shock Wave Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Root Resorption and Dehiscence Formation Between Two Methods of Leveling and Alignment of Lower Teeth
Status: COMPLETED
Conditions: Crowding of Anterior Mandibular Teeth
Interventions: PROCEDURE: Corticision|OTHER: Traditional Non-accelerated Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Intervention Protocol With Inspirometer Versus 2 Modalities of Pulmonary Intervention: INSPUL-REHAB
Status: UNKNOWN
Conditions: Breathing Exercises
Interventions: DEVICE: Respiratory muscle training 1|OTHER: Respiratory muscle training 2|OTHER: Respiratory muscle training 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pain Neurophysiology Education in Combination With Motor Control Training for Unspecific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: BEHAVIORAL: motor control training|BEHAVIORAL: pain neurophysiology education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing ATB200/AT2221 With Alglucosidase Alfa/Placebo in Adult Subjects With Late-onset Pompe Disease
Status: COMPLETED
Conditions: Pompe Disease (Late-onset)
Interventions: BIOLOGICAL: Cipaglucosidase Alfa|DRUG: Miglustat|BIOLOGICAL: Alglucosidase Alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or Placebo
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Seroquel (quetiapine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodiumhexametaphosphate Versus MTA as Pulp Capping Material for Immature Permanent Teeth
Status: NOT_YET_RECRUITING
Conditions: Pulp Disease, Dental
Interventions: OTHER: Pulp capping|DRUG: Sodiumhexametaphosphate|OTHER: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Pazopanib Tablets in Patients Who Have Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Telehealth In-home Messaging to Improve GI (Gastrointestinal) Endoscopy Completion Rates
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Use of Interactive Voice Response (IVR) system to improve adherence to GI appointments and prep procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Novel Epothilone (BMS-247550) in Patients With Metastatic Breast Cancer (MBC)
Status: COMPLETED
Conditions: Breast Cancer|Metastases
Interventions: DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Volume and Pressure-Controlled Ventilation on Cerebral SpO2, PI, and PVI Index in Septoplasty
Status: COMPLETED
Conditions: Ventilation Mode|Pleth Variability Index|Perfusion Index|Regional Cerebral Oxygen Saturation
Interventions: DIAGNOSTIC_TEST: Cerebral Oxygen Saturation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Ischemic Conditioning for Reducing Stroke Risk of Symptomatic Vertebrobasilar Lesion of Atherosclerosis
Status: UNKNOWN
Conditions: Vertebrobasilar Ischemia
Interventions: DEVICE: ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of BAY3427080 (NT-814) in the Treatment of Moderate to Severe Post-menopausal Vasomotor Symptoms
Status: COMPLETED
Conditions: Menopause|Hot Flashes|Night Waking
Interventions: DRUG: Elinzanetant (BAY3427080)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DynaCT Imaging in EVAR: Comparing Clinical Benefit of DynaCT to Multidetector CT as the Current Gold Standard.
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: PROCEDURE: DynaCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Canadian Open-Label Study to Evaluate the Safety and Effectiveness of Adalimumab When Added to Inadequate Therapy for the Treatment of Psoriatic Arthritis (PsA) (ACCLAIM)
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Single Dose D-Cycloserine on Cognitive Outcome in Moderate Traumatic Brain Injury (TBI) Patients
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DRUG: D-cycloserine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Limitations of Offering Community Based Rapid HIV Testing to Men Who Have Sex With Men (MSM)
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: blood test: rapid finger-stick blood specimen test|BIOLOGICAL: blood test: conventional test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Of Two Oral Preparations Of 2 Mg Alprazolam In Healthy Volunteers Under Fasting Conditions
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Alprazolam|DRUG: Alprazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Safety Study for RWJ-333369 as Adjunctive Therapy in Korean and Japanese Patients With Partial Onset Seizures
Status: TERMINATED
Conditions: Seizures
Interventions: DRUG: RWJ-333369|DRUG: RWJ-333369|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stepped Care Versus Group Cognitive Behaviour Therapy for Paediatric Anxiety in Primary Care
Status: NOT_YET_RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Step-by-step|BEHAVIORAL: Cool Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Therapeutic Mobile App for Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression
Interventions: DEVICE: Gamified Attention Bias Modification|DEVICE: Gamified Placebo Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of 12-weeks of Sovaprevir, ACH-3102, and Ribavirin in Treatment-naive GT-1 HCV Participants
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sovaprevir|DRUG: ACH-3102|DRUG: Ribavirin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-blind, Placebo Controlled, Multi-center and Tolerability of RBP-7000 in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: RBP-7000|DRUG: Placebo|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation With a Highly-Concentrated Docosahexaenoic Acid (DHA) Triglyceride in Patients With Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: DIETARY_SUPPLEMENT: Highly-concentrated DHA triglyceride (Tridocosahexanoin-AOX 70%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tamoxifen Versus Toremifene in CYP2D6 IM/PM of Premenopausal Patients With ER-positive Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: Tamoxifen|DRUG: Toremifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab Maintenance Therapy After Autologous Stem Cell Transplant in Hodgkin Lymphoma Pts at Relapse/Progression Risk
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Life's End Benefits of Cannabidiol and Tetrahydrocannabinol
Status: RECRUITING
Conditions: Agitation|Dementia
Interventions: DRUG: T2:C100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Refractory Plasma Cell Myeloma
Interventions: DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Vascular Inflammation|Coronary Atherosclerosis
Interventions: BIOLOGICAL: adalimumab|DEVICE: UVB Phototherapy|OTHER: Topical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3)
Status: COMPLETED
Conditions: Huntington Disease|Parkinson Disease
Interventions: BEHAVIORAL: MindTrails
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Testosterone on Mood and Quality of Life
Status: COMPLETED
Conditions: Gonadal Disorders|Depressive Disorder|Hypogonadism
Interventions: DRUG: Testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Sport Project; Preventing Eating Disorders in Sport
Status: COMPLETED
Conditions: Eating Disorders|Body Dissatisfaction|Disordered Eating|Adolescent - Emotional Problem|Athletic Injuries
Interventions: BEHAVIORAL: Healthy Sport Project
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study With Minimal Residual Disease (MRD) Driven Adaptive Strategy in Treatment for Newly Diagnosed Multiple Myeloma (MM) With Upfront Daratumumab-based Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study
Status: RECRUITING
Conditions: NSCLC|SCLC|Colorectal Cancer|Pancreas Cancer|TNBC - Triple-Negative Breast Cancer|DLBCL - Diffuse Large B Cell Lymphoma|Squamous Cell Carcinoma of Head and Neck
Interventions: BIOLOGICAL: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Ciprofloxacin Extended-Release Tablets 1000 mg and Cipro® XR Tablets 1000 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ciprofloxacin Extended-Release Tablets 1000 mg|DRUG: Cipro® XR Tablets 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Follicular Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Zanubrutinib|DRUG: Rituximab|DRUG: Lenalidomide|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Proteasome Inhibitor PR-171 (Carfilzomib for Injection) in Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia|Non-Hodgkin's Lymphoma|Hodgkin's Disease|Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Yttrium-90 in Treating Patients With Liver Cancer Undergoing Surgical Resection
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Nivolumab|RADIATION: Yttrium Y 90 Glass Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transitional Care Model Evaluation 2020
Status: ACTIVE_NOT_RECRUITING
Conditions: CHF - Congestive Heart Failure|COPD|Pneumonia
Interventions: BEHAVIORAL: Transitional care model (TCM)|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BAY38-9456 - Supportive Trial for Spinal Injury
Status: COMPLETED
Conditions: Erectile Dysfunction|Sexual Dysfunction|Spinal Cord Injury
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Different Forms of Glucocorticoid on the Recovery of Reproductive Function in Patients With 21α-hydroxylase Deficiency
Status: UNKNOWN
Conditions: Congenital Adrenal Hyperplasia
Interventions: DRUG: Hydrocortisone|DRUG: Prednisone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Peas in Soup on Blood Glucose Control
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-prandial Glycaemia
Interventions: DIETARY_SUPPLEMENT: Whole yellow pea soup|DIETARY_SUPPLEMENT: Split yellow pea soup|DIETARY_SUPPLEMENT: Potato soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Risk of Surgical Site Infections Between Dressings Stopped at Postoperative Day 1 vs Dressings Stopped at Postoperative Day 6+/-1 After Elective Abdominal Surgery
Status: NOT_YET_RECRUITING
Conditions: Elective Abdominal Surgery
Interventions: PROCEDURE: Postoperative day 1 dressing|PROCEDURE: Postoperative day 6+/-1 dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mitoxantrone Hydrochloride Liposome Combination Regimen in the Treatment of High-risk/Extramedullary Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Lipo-MIT combination regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasted Bioavailability Study of Cilostazol Tablets, 100 mg
Status: COMPLETED
Conditions: Therapeutic Equivalency
Interventions: DRUG: Cilostazol 100 mg Tablets|DRUG: Cilostazol (Pletal®) 100 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Concentrated Citrate Locking to Reduce the Incidence of CVC-related Complications in Hematological Patients
Status: TERMINATED
Conditions: Hematological Malignancies|Bacteremia|Thrombosis
Interventions: PROCEDURE: heparin|PROCEDURE: concentrated citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tissue Distribution, Pharmacokinetics, Safety, and Tolerability After a Single Dose of TNP-2092 in Participants Undergoing Primary Total Hip or Knee Arthroplasty
Status: COMPLETED
Conditions: Prosthetic Joint Infection
Interventions: DRUG: TNP-2092
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gram Stain of the First Urine After Puncture in Percutaneous Nephrolithotomy
Status: RECRUITING
Conditions: Percutaneous Nephrolithotomy
Interventions: DIAGNOSTIC_TEST: Gram staining of the first urine after intraoperative renal puncture to predict the systemic inflammatory response after percutaneous nephrolithotomy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Green Tea Extract on Soluble RAGE in Patients With Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy Type 2
Interventions: DRUG: green tea extract|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Geriatric Assessment and Head and Neck Elderly Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinomas (HNSCCs)
Interventions: OTHER: CGA and geriatric follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Swaddling and Inhaling Breast Milk Odour on the Pain and Comfort
Status: COMPLETED
Conditions: Infant, Newborn|Pain Perception
Interventions: OTHER: swaddled|OTHER: mother's breast milk odor|OTHER: both swaddled and made to inhale mother's breast milk odor|OTHER: No procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Deep Breathing Excercises With and Without PMR on Depression & QOL in Females With Hystrectomy
Status: COMPLETED
Conditions: Post-Hysterectomy Vaginal Vault Prolapse
Interventions: OTHER: Deep breathing excercises|OTHER: Deep breathing exercises +and progressive muscle relaxation techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Anticoagulation in Haemodialysis Patients
Status: TERMINATED
Conditions: Kidney Failure, Chronic
Interventions: BIOLOGICAL: No oral anticoagulation|DRUG: Oral anticoagulation with vitamin K antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine Followed by a Cancer Antigen Vaccine for Patients With Neuroblastoma and Sarcoma
Status: COMPLETED
Conditions: Neuroblastoma|Ewings Sarcoma|Osteogenic Sarcoma|Rhabdomyosarcoma|Synovial Sarcoma
Interventions: BIOLOGICAL: Autologous dendritic cell vaccine with adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 4, Randomized, Double-blind, Placebo-controlled,Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: SAR231893|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wrist Arthroscopy Study
Status: COMPLETED
Conditions: Wrist Arthropathy
Interventions: DIAGNOSTIC_TEST: Diagnostic Arthroscopy using the Arthrex NanoScope|DIAGNOSTIC_TEST: Diagnostic Arthroscopy using standard arthroscopic instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Neuroprosthesis for Prolonged Standing After SCI Using Multi-Contact Peripheral Nerve Electrodes
Status: COMPLETED
Conditions: Spinal Cord Injury|Paralysis|Tetraplegia|Paraplegia
Interventions: DEVICE: IST-16 (16-Channel implanted stimulator-telemeter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate the Drug-drug Interaction of BMS-986196 With Oral Contraceptives in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy Female Volunteers
Interventions: DRUG: BMS-986196|DRUG: Loestrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Dexamethasone on the Duration of Sensory and Motor Block Following Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia|Prolonged Sensory Block|Prolonged Motor Block
Interventions: DRUG: Dexamethasone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Biological Characterization Study of an Autograft Nanofat (Nanocarabio)
Status: COMPLETED
Conditions: Rhizarthrosis
Interventions: PROCEDURE: collecting a Nanofat-type microfat autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder
Status: RECRUITING
Conditions: Urinary Bladder Neoplasms
Interventions: BIOLOGICAL: Cetrelimab|DRUG: TAR-200|DRUG: Cisplatin|DRUG: Gemcitabine|RADIATION: Conventional radiation therapy|RADIATION: Hypo-fractioned radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Using a Novel Bi-directional Device
Status: COMPLETED
Conditions: Bilateral Nasal Polyposis
Interventions: DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer
Status: RECRUITING
Conditions: Advanced Head and Neck Squamous Cell Carcinoma|Advanced Hypopharyngeal Squamous Cell Carcinoma|Advanced Laryngeal Squamous Cell Carcinoma|Advanced Oropharyngeal Squamous Cell Carcinoma|Squamous Cell Carcinoma of Unknown Primary
Interventions: DRUG: Cisplatin|DRUG: Cisplatin|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip
Status: COMPLETED
Conditions: Osteoarthritis of the Shoulder|Osteoarthritis of the Hip
Interventions: DRUG: FX006 32 mg|DRUG: TAcs 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Interleukin-2 in Treating Patients With Stage III, Stage IV, or Recurrent Follicular Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: autologous tumor cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Intensive Glycemic Control For Diabetic Foot Ulcer Healing
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Insulin Glargine|DRUG: Diabetic DM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VI-1121 for the Treatment Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: VI-1121|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Responsiveness and Outcome in Coronary Artery Bypass Graft (CABG) Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Triple Vessel|Myocardial Ischemia|Thrombosis|Antithrombotic Drugs [Platelet-aggregation Inhibitors] Causing Adverse Effects in Therapeutic Use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREvention of VENous ThromboEmbolism Following Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer|Venous Thromboembolism|Lymphocele After Surgical Procedure|Deep Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: Subcutaneous Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: JET-RANGER Trial - JETStream Atherectomy With Adjunctive Paclitaxel-Coated Balloon Angioplasty vs Plain Old Balloon Angioplasty Followed by Paclitaxel-Coated Balloon
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Jetstream Atherectomy with randomization to the Ranger or IN.PACT DCB Arm or the POBA+DCB (Ranger or IN.PACT) Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pain Management Following Sinus Surgery
Status: TERMINATED
Conditions: Nasal Sinus; Inflammation|Opioid Abuse|Pain, Postoperative
Interventions: DRUG: Ibuprofen 600Mg Tablet|OTHER: Standard Regimen | Tylenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amount of Correction of Torsional Deformity in Blount's Disease After Coronal Plane Deformity Correction by 8 Plate Hemiepiphysiodesis
Status: UNKNOWN
Conditions: Blount Disease
Interventions: PROCEDURE: 8 plate hemiepiphysiodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Fruquintinib Combined With Raltitrexed in the Treatment of Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Upper Limb Training in Chronic Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Queen Square Upper Limb Neurorehabilitation Programme|DEVICE: Immersive gaming therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Positive End Expiratory Pressure (PEEP) During Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Brain Ischemia
Interventions: OTHER: PEEP|OTHER: ZEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Radiation Therapy, Hormonal Therapy and Concurrent Docetaxel for High Risk Pathologic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|RADIATION: Radiation Therapy|DRUG: Casodex and Zoladex (or Lupron)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT