pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients
Status: COMPLETED
Conditions: Tooth; Lesion, White Spot Lesions
Interventions: DRUG: elmex® gelée|DRUG: negative control (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA
Status: COMPLETED
Conditions: Asymptomatic Hyperuricemia
Interventions: DRUG: Verinurad|DRUG: Febuxostat|DRUG: Dapagliflozin|OTHER: Dapagliflozin matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)
Status: COMPLETED
Conditions: Cancer|Lymphoma|Leukemia
Interventions: DRUG: palifermin|RADIATION: Total Body Irradiation|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Isoniazid Prophylaxis Based on Risk Factors of Tuberculosis in Living Kidney Transplantation Recipients
Status: COMPLETED
Conditions: Kidney Transplantation|Tuberculosis|Isoniazid Toxicity
Interventions: DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Consumption of Supplements and Enriched Olive Paste on Bone Metabolism Indices
Status: COMPLETED
Conditions: Osteopenia or Osteoporosis
Interventions: OTHER: Functional olive paste|OTHER: Calciovitmag (CDCaMg)|OTHER: Phosporovitmag (PDCaMg)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Response of the Myocardium to Hypertrophic Conditions in the Adult Population
Status: RECRUITING
Conditions: Left Ventricular Hypertrophy|Hypertension|Myocardial Fibrosis
Interventions: OTHER: Cardiovascular Magnetic Resonance|OTHER: Echocardiogram|OTHER: Electrocardiogram|DEVICE: Ambulatory Blood Pressure Monitoring|OTHER: Retinal Photography (Optional)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis Hand
Interventions: BIOLOGICAL: SclerFIX-IP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Antimalarial Drugs Used in Pregnancy in Tanzania
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: SP|DRUG: SP + amodiaquine|DRUG: AQ + artesunate|DRUG: chlorproguanil-dapsone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Pimasertib|DRUG: Placebo|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Colon Cancer|Lung Cancer|Gastric Cancer|Solid Tumors
Interventions: DRUG: Veliparib (ABT-888)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Trial to Improve Multisensory Neural Processing, Language & Motor Outcomes in Preterm Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Infant
Interventions: BEHAVIORAL: Therapist skin-to-skin Care|DEVICE: Contingent parent's voice exposure|BEHAVIORAL: Parental skin-to-skin care|DEVICE: Recorded parent's voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clearum High Flux Hemodialyzer Used in Hemodialysis for Subjects With End-Stage Renal Disease
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DEVICE: Clearum HF Hemodialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Determinants of the Progression of Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DIAGNOSTIC_TEST: Doppler-echocardiography|RADIATION: Computed tomography|OTHER: Magnetic resonance imaging|BIOLOGICAL: Fasting blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.
Status: RECRUITING
Conditions: Contrast-induced Acute Kidney Injury (CI-AKI) Following Coronary Angiogram (CI-AKI)|Contrast-induced Nephropathy Following Coronary Angiogram (CIN)
Interventions: OTHER: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Evolocumab on Vascular Function
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Evolocumab Prefilled Syringe|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Pharmacokinetic Clenil Study With AeroChamber Plus™ or Volumatic™ Spacer Devices
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Clenil® Modulite® via AeroChamber Plus™|DRUG: Clenil® Modulite® via Volumatic™ spacer|DRUG: Clenil® Modulite® via AeroChamber Plus™ plus charcoal block|DRUG: Clenil® Modulite® administered via Volumatic™ spacer plus charcoal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I)
Status: COMPLETED
Conditions: Safety and Tolerability|Compare SHINGRIX Vaccine Response Rates|Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: BIOLOGICAL: Zoster Vaccine Recombinant, Adjuvanted
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Buspirone Plus Omeprazole for Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Buspirone|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients
Status: TERMINATED
Conditions: Second or Third Degree Burns
Interventions: DRUG: Fenofibrate|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: DC-806|DRUG: Midazolam|DRUG: Repaglinide|DRUG: Digoxin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Licorice Root Extract and Docetaxel in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: licorice root extract|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Cognition Via Exercise and Nutrition
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Function 1, Social
Interventions: BEHAVIORAL: BAILAMOS dance program plus MIND diet|BEHAVIORAL: BAILAMOS dance program plus Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Use of Entecavir for HBsAg Negative/HBcAb Positive/Hepatitis B Virus DNA Negative Patients With Lymphoma
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: Entecavir prophylaxis|DRUG: Observation arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ONO-4578-06:Phase I Study of ONO-4578 and Letrozole Plus CDK4 /6 Inhibitors in Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Receptor-positive Breast Cancer|HER2-negative Breast Cancer|Metastatic Breast Cancer|Recurrent Breast Cancer
Interventions: DRUG: ONO-4578|DRUG: letrozole|DRUG: Palbociclib|DRUG: abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel)
Status: TERMINATED
Conditions: Fracture Fixation|Intra-Articular Fractures|Acetabulum
Interventions: DEVICE: Vitagel|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sanofi H1N1 Influenza Vaccine Administered at Two Dose Levels in Adult and Elderly Populations
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated H1N1 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial
Status: COMPLETED
Conditions: Suicide|Suicide and Self-harm|Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Mobile Application to Prevent Suicide (MAPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REBIRTH Active School 2.0 . A School Based Physical Activity Program
Status: RECRUITING
Conditions: Primary School Children
Interventions: BEHAVIORAL: Rebirth active SCHOOL 2.0 movement program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Interleukin-2 (IL-2) Plus Anti-HIV Therapy in HIV-Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Aldesleukin|DRUG: HAART
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer Metastatic|Colorectal Cancer Metastatic
Interventions: DRUG: Neoantigen Vaccine with Poly-ICLC adjuvant|DRUG: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anti-angiogenic Therapy With IV Bevacizumab in Patients With Symptomatic Cerebral Arteriovenous Malformations
Status: NOT_YET_RECRUITING
Conditions: Cerebral AV Malformation
Interventions: DRUG: Bevacizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects AZD8529 on Cognition and Negative Symptoms in Schizophrenics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: AZD8529|DRUG: Placebo to match AZD8529
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: the Dietary Effects of VitaSugar/VitaFiber-IMO in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Isomaltooligosaccharide (digestion-resistant carbohydrates)|OTHER: Isomaltooligosaccharide (digestion-resistant carbohydrates)|OTHER: Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Use of Topical Anaesthetic in the Banding of Internal Haemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Instillagel|OTHER: KY Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-Therapy Study of Experimental Medication BMS-986242 Given in Combination With Nivolumab in Patients With Advanced Cancer
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: BMS-986242|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Lithotripsy Versus Visual Cystolitholapaxy in The Management of Patients Presenting With Calcular Acute Urinary Retention: A Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Urinary Calculi
Interventions: PROCEDURE: ESWL|PROCEDURE: Endoscopic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GS-6624
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dexmedetomidine and Delirium in Elderly Patients
Status: UNKNOWN
Conditions: Delirium, Dexmedetomidine, Postoperative PCA
Interventions: DRUG: Dexmedetomidine|DRUG: Fentanyl-based PCA infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treating Primary Progressive Aphasia (PPA) Using tDCS
Status: RECRUITING
Conditions: Primary Progressive Aphasia
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham tDCS|BEHAVIORAL: Modified Contraint-Induced Language Therapy (mCILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Childhood Maltreatment, Traumatic Experiences and Stress-associated Parameters in Schizophrenia Spectrum Disorders
Status: COMPLETED
Conditions: Schizophrenia Spectrum Disorder|PTSD
Interventions: BEHAVIORAL: Narrative Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema
Status: RECRUITING
Conditions: Alpha 1-Antitrypsin Deficiency|Emphysema
Interventions: DRUG: INBRX-101|DRUG: Zemaira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Significance of Hepatic Biomarkers in Lung Cancer Patients Treated With Immune Checkpoint Inhibitors
Status: WITHDRAWN
Conditions: Immune Checkpoint Inhibitor|Lung Cancer|Liver Biomarkers|Transaminases
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Misoprostol Versus Dilapan-S for Cervical Preparation
Status: COMPLETED
Conditions: Cervical Ripening
Interventions: DRUG: misoprostol|DEVICE: Dilapan-S, vitamin B-12
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment of BV With First Deqularum and Then Direkt After Clindamycin
Status: UNKNOWN
Conditions: Infection, Bacterial
Interventions: DRUG: treatment of BV with first Deqularum and then direkt after with vaginal clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab 100 mg|DRUG: Placebo for guselkumab|DRUG: Adalimumab|DRUG: Placebo for adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Monitoring and Home-based Health Care for Treatment of Bone Marrow Transplant Patients
Status: COMPLETED
Conditions: Bone Marrow Transplant
Interventions: DEVICE: BioIntellisense BioSticker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Morphine for Dyspnea in Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: Morphine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation
Status: NOT_YET_RECRUITING
Conditions: Bladder Hyperactivity|Sacral Neuromodulation
Interventions: DEVICE: Medical device for SNM: Interstim II, Interstim micro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Long-term Health Status and Quality of Life in Adult Survivors With Philadelphia-negative Acute Lymphoblastic Leukemia/Lymphoma Treated With an Intensive Pediatric or Pediatric-inspired Protocol
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|Acute Lymphoblastic Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PeAF-BOX: Feasibility, Safety and Efficacy of PVI + Box Ablation in Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Left atrial combined pulmonary vein isolation and posterior wall isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial and Focused ESWT in the Treatment of Coccydynia According to Age and Body Mass Index
Status: COMPLETED
Conditions: Coccyx Disorder
Interventions: DEVICE: ESWT (wave type: focused)|DEVICE: ESWT (wave type: radial)|DEVICE: ESWT (wave type: sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Semi-recumbent Position With Exercise Training on Long-term Ventilator-dependent Patients
Status: COMPLETED
Conditions: Mechanical Ventilation|Difficult Intubation|Position|Exercise
Interventions: BEHAVIORAL: 45 Degree Semi-recumbent Position With Upper Limb Exercise Training|BEHAVIORAL: no 45 Degree Semi-recumbent Position With Upper Limb Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics of an Oral Contraceptive Containing Levonorgestrel and Ethinyl Estradiol When Co-administered With GSK1265744 in Healthy Adult Female Subjects
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Hepatitis
Interventions: DRUG: Ethinyl Estadiol|DRUG: Levonorgestrel|DRUG: GSK1265744
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Use of Rituximab in Acute Thrombotic Thrombocytopenic Purpura (TTP)
Status: COMPLETED
Conditions: Thrombotic Thrombocytopenic Purpura (TTP)
Interventions: DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancement of in-Vitro GC Function in Patients With COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Fluticasone Propionate|DRUG: placebo|DRUG: Theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy in Borderline Resectable and Locally Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Pancreatic Adenocarcinoma|Chemotherapy Effect|Borderline Resectable Pancreatic Adenocarcinoma|Pancreatectomy
Interventions: DRUG: Folfirinox
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Reality-Base Intelligent Orientation and Mobility Specialists Trial
Status: RECRUITING
Conditions: Low Vision, Both Eyes
Interventions: BEHAVIORAL: Orientation and Mobility Training with VR-IOMSs|BEHAVIORAL: Orientation and Mobility Training with COMS|BEHAVIORAL: No Orientation and Mobility Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Thoracic Manipulation on Hip Adductor, Extensor, and Latissimus Dorsi Force in Those With Adductor Weakness
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: PROCEDURE: High velocity low amplitude thoracic spine manipulation|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: REspiratory MEchanics for Delivering Individualised Exogenous Surfactant
Status: NOT_YET_RECRUITING
Conditions: Respiratory Distress Syndrome in Premature Infant
Interventions: OTHER: Surfactant administration following lung mechanics assessment in addition to clinical assessment|OTHER: Surfactant administration following clinical assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Deproteinized Bovine Bone Mixed With Injectable Platelet Rich Fibrin Versus a Sole Deproteinized Bovine Bone "TUTOGEN BONE" in Sinus Floor Elevation With Simultaneous Implant Placement. A Randomized Clinical Trial
Status: UNKNOWN
Conditions: Sinus Floor Elevation
Interventions: PROCEDURE: sinus lift, implant placement, sole bovine bone|PROCEDURE: sinus lift, implant placement, injectable PRF + bovine bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Stem Cell Transplantation in Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: autologous hematopoiesis stem cell transplantation|DRUG: Aspirin|DRUG: Warfarin|DRUG: Atorvastatin|DRUG: Edaravone|DRUG: Aspirin|DRUG: Warfarin|DRUG: Atorvastatin|DRUG: Edaravone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites
Status: COMPLETED
Conditions: Cirrhosis|Ascites|Peritonitis
Interventions: DRUG: Rifaximin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Exercise in Diastolic Heart Failure
Status: COMPLETED
Conditions: Diastolic Heart Failure|Heart Failure With Preserved Ejection Fraction
Interventions: BEHAVIORAL: Functional circuit training and lifestyle counseling|BEHAVIORAL: Health education and independent walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clonidine With Morphine in Patient Controlled Analgesia Pump in Vaso-Occlusive Crisis in Sickle Cell Disease Patient
Status: RECRUITING
Conditions: Sickle Cell Disease|Vaso-occlusive Pain Episode in Sickle Cell Disease
Interventions: DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of McGrath, Pentax and Macintosh Laryngoscopes for Nasotracheal Intubation in Pediatrics
Status: COMPLETED
Conditions: Intubation Time|Intubation Difficulty Scale
Interventions: DEVICE: Macintosh laryngoscope|DEVICE: McGrath videolaryngoscope|DEVICE: Pentax videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Evaluate the Safety and Feasibility of spCART-269 Injection in the Treatment of MM
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Targeting CD269 chimeric antigen receptor engineered T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion
Status: UNKNOWN
Conditions: Lung Cancer|Breast Cancer|Malignant Pleural Effusion
Interventions: DRUG: microparticles packaging methotrexate (MPs-MTX)|DRUG: recombinant human interleukin-2(rhIL-2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: DEVICE: High-frequency (10Hz) rTMS|DEVICE: Anodal tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0415 Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-field Magnetic Resonance Imaging in Pediatric Post Covid-19
Status: UNKNOWN
Conditions: COVID-19|COVID-19 Respiratory Infection|Long COVID
Interventions: DIAGNOSTIC_TEST: Low-field magnetic resonance imaging|DIAGNOSTIC_TEST: Nailfold capillaroscopy|DIAGNOSTIC_TEST: Spiroergometry|DIAGNOSTIC_TEST: Realtime deformability cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Illiteracy and Vulnerability to Alzheimer's Disease: Evaluation of Amyloid Pathology by PET Imaging
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: RADIATION: Fluorodeoxyglucose-PET|RADIATION: florbetapir F 18-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Caesarean Delivery With or Without an Indwelling Bladder Catheter. A Randomised Trial.
Status: TERMINATED
Conditions: Cesarean Section; Infection|Catheter-Related Infections
Interventions: PROCEDURE: Without placement of a catheter|PROCEDURE: With placement of a catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharyngeal Size in Patients With Obstructive Tonsils Under Orthodontic Treatment
Status: COMPLETED
Conditions: Sleep Apnea Syndrome|Malocclusion
Interventions: DEVICE: Bioajusta X Orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
Status: ENROLLING_BY_INVITATION
Conditions: Anesthesia|Analgesia
Interventions: PROCEDURE: Epidural|PROCEDURE: Dural Puncture Epidural (DPE) technique|PROCEDURE: Combined Spinal-Epidural (CSE) technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-endodontic Pain Survey
Status: COMPLETED
Conditions: Postoperative Pain|Endodontic Disease|Obturation
Interventions: PROCEDURE: Non-surgical root canal treatment filled with WVT|PROCEDURE: Non-surgical root canal treatment filled with SBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Referral From Primary Health Care Centers to a Physical Activity Program. A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Sedentary General Population
Interventions: BEHAVIORAL: Physical activity intervention|BEHAVIORAL: Health educational program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DEVICE: Novel Smart Speculum|DEVICE: Standard speculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Antioxidant Micronutrients in Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Amodiaquine + Artesunate|DRUG: Amodiaquine + Artesunate|DRUG: Lumefantrine + Artemether|DIETARY_SUPPLEMENT: Artesunate + vitamin A|DIETARY_SUPPLEMENT: Artesunate + vitamin E|DIETARY_SUPPLEMENT: Artesunate + Zinc|DIETARY_SUPPLEMENT: Artesunate + selenium|DIETARY_SUPPLEMENT: Amodiaquine + vitamin A|DIETARY_SUPPLEMENT: Amodiaquine + Vitamin E|DIETARY_SUPPLEMENT: Amodiaquine + Zinc|DIETARY_SUPPLEMENT: Amodiaquine + Selenium|DIETARY_SUPPLEMENT: Artesunate + vitamin A + vitamin E|DIETARY_SUPPLEMENT: Artesunate + Vitamin A + Zinc|DIETARY_SUPPLEMENT: Artesunate + Vitamin A + Selenium|DIETARY_SUPPLEMENT: Artesunate + Vitamin E + Selenium|DIETARY_SUPPLEMENT: Artesunate + Vitamin E + Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Central Serous Chorioretinopathy Via Electromagnetic Stimulation and Platelet- Rich Plasma
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy|Chronic Central Serous Chorioretinopathy
Interventions: COMBINATION_PRODUCT: Source of growth factors: autologous platelet-rich plasma (aPRP) + repetitive electromagnetic stimulation for iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, First-in-human Study of VX-634
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: VX-634|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine the Bioequivalence of Two Formulations of Tamsulosin HCl Capsules in Fasted Male.
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: tamsulosin capsules|DRUG: tamsulosin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Phase I Study of BFI-751 Compared With EU and US-STELARA® in Healthy Adults
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BFI-751|DRUG: EU-STELARA®|DRUG: US-STELARA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Additional Oral Preparation on the Quality of Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation Quality
Interventions: DRUG: Additional oral preparation (3L of PEG+Asc, "Coolprep®")|DRUG: Standard oral preparation (2L of PEG+Asc, "Coolprep®")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Toripalimab Injection (JS001) + Cetuximab in Treatment of Advanced Head and Neck Squamous Cell Cancer
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Cancer
Interventions: DRUG: Toripalimab Injection|DRUG: Cetuximab Solution for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Safety of Q8003 Versus Morphine Equivalent Doses of Its Components (Oxycodone and Morphine) in Bunionectomy Patients
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Q8003 (morphine sulfate and oxycodone hydrochloride)|DRUG: Morphine sulfate|DRUG: Oxycodone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC)
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: TACE protocol|DRUG: Neoadjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-1
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Hyperparathyroidism|End-stage Kidney Disease (ESKD)
Interventions: DRUG: PLS240|DRUG: Placebo|DRUG: Open-Label Extension PLS240
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Postoperative Recovery (QoR-15T) in Patients Undergoing Video-Assisted Thoracoscopic Surgery (VATS)
Status: RECRUITING
Conditions: Video-Assisted Thoracic Surgery
Interventions: OTHER: Preoperative Quality of Recovery-15 (QoR-15T)|OTHER: Postoperative 24th hour Quality of Recovery-15 (QoR-15T)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Laser Light Therapy After Impacted Third Molar Removal
Status: UNKNOWN
Conditions: Trismus|Edema|Pain
Interventions: DEVICE: Extra-oral laser irradiation|DEVICE: Intra-oral laser irradiation|DEVICE: Extra-oral placebo|DEVICE: Intra-oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vocal-cord vs. Complete Laryngeal Radiotherapy for Early Glottic Cancer
Status: RECRUITING
Conditions: Cancer Neck|Larynx Cancer|Glottis Tumor
Interventions: RADIATION: Vocal-cord Radiotherapy|RADIATION: Complete Larynx Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Conventional Therapy and Low Level Laser Therapy on Pain and Function in Patients With Temporomandibular Joint Dysfunction
Status: COMPLETED
Conditions: Low Level Laser Therapy|Temporomandibular Joint Dysfunction
Interventions: OTHER: conventional therapy|OTHER: low level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ALK21-014: Efficacy and Safety of Medisorb® Naltrexone (VIVITROL®) After Enforced Abstinence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: VIVITROL 380 mg|DRUG: Placebo for VIVITROL 380 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation Alone or in Combination With Substrate Modulation After Electric Cardioversion Failure
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary Vein Isolation (PVI) alone|PROCEDURE: PVI procedure associated with substrate modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation
Status: NOT_YET_RECRUITING
Conditions: Cytomegalovirus (CMV)|Kidney Disease|Kidney Failure
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer Surgery
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Total Operative time|PROCEDURE: Margin assessment|PROCEDURE: Conversion rate to open surgery|PROCEDURE: Baseline demographics|PROCEDURE: Preoperative data|PROCEDURE: Postoperative data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess Efficacy, Safety, Treatment Adherence and Quality of Life Impact of Mometasone Furoate in Asthmatic Patients (Study P04879)(TERMINATED)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Mometasone Furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of Curalin As Add-On Therapy in Adults With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Curalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the iD-SystemTM, One-Handed Disposable Internal Defibrillation System.
Status: COMPLETED
Conditions: Ventricular Fibrillation|Ventricular Tachycardia
Interventions: PROCEDURE: Internal defibrillation during cardiac surgery, using the iD-system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Aeriseal ® in the Management of Collateral Ventilation Positive COPD Patients Undergoing ELVR Utilizing Endobronchial Valves.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Lung Sealant|DEVICE: Endobronchial Valve (EBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Urgency Through Relaxation Exercises
Status: COMPLETED
Conditions: Overactive Bladder|Urgency Urinary Symptoms|Urgency Incontinence
Interventions: BEHAVIORAL: Paced Respiration|BEHAVIORAL: Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Flaps for Nasal Surgical Wounds RCT
Status: NOT_YET_RECRUITING
Conditions: Surgical Wound
Interventions: PROCEDURE: Nasalis Sling Flap|PROCEDURE: Lobed Transposition Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study on Tolerance, Pharmacokinetics and Drug Interaction of YK-1169 in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Group 1:YK-1169|DRUG: Group 2:YK-1169/Placebo Injection|DRUG: Group 3:YK-1169/Placebo|DRUG: Group 4:YK-1169/Placebo|DRUG: Group 5:YK-1169/Placebo Injection|DRUG: Group 6:YK-1169/Cefepime hydrochloride for injection/Avibactam for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: KRAS NP_004976.2:p.G12D|Metastatic Pancreatic Adenocarcinoma|Pancreatic Ductal Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Mesenchymal Stromal Cells-derived Exosomes with KRAS G12D siRNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a New Imaging Agent to Identify Cancer
Status: RECRUITING
Conditions: HER-2 Positive Malignant Carcinoma of Breast|HER-2 Protein Overexpression|HER2-positive Metastatic Breast Cancer
Interventions: COMBINATION_PRODUCT: 89Zr-ss-pertuzumab PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Viloxazine and Its Metabolite 5-Hydroxy-viloxazine Glucuronide Into Breast Milk in Healthy Lactating Women
Status: COMPLETED
Conditions: Healthy Lactating Women
Interventions: DRUG: SPN-812 (600mg, QD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cervical Exercise in Peripheral Vestibular Disorders
Status: COMPLETED
Conditions: Vestibular Disorder|Peripheral Vestibular Disorder
Interventions: OTHER: Only vestibular rehabilitation|OTHER: Cervical exercises in addition to vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Fexinidazole Dosing Regimens for the Treatment of Adult Patients With Chagas Disease
Status: UNKNOWN
Conditions: Chagas Disease|Trypanosomiasis, South American|South American Trypanosomiasis|Disease, Chagas
Interventions: DRUG: Fexinidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Task-oriented Game Therapy Using Enhances Functions in Children With Cerebral Palsy.
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Task-oriented Fruit ninja game|OTHER: sham-controlled therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Safety and Immunogenicity Phase I Study of HLX14 Versus Prolia® in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: HLX14|DRUG: EU-Prolia®|DRUG: US-Prolia®|DRUG: CN-Prolia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Combined Hypo Gastric Neural Plexus Block and Uterosacral Nerve Block for Patients With Chronic Idiopathic Pelvic Pain
Status: RECRUITING
Conditions: Chronic Idiopathic Pain Syndrome
Interventions: DRUG: MARCAINE AND BETAMETHAZONE 1|DRUG: MARCAINE AND BETAMETHAZONE 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing PREschooler Care, Community Resources, Advocacy, Referral, Education (PRE-CARE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention Deficit/Hyperactivity Disorder|Inattention
Interventions: OTHER: Screening|OTHER: Resource Packet|OTHER: Resource Navigation|OTHER: Care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Reactivity After an Eastern Asian Loading Dose of Prasugrel in Taiwanese ACS Patients
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Hemorrhage|Treatment Side Effects
Interventions: DIAGNOSTIC_TEST: P2Y12-reaction-units (PRU) by VerifyNow-P2Y12 assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
Status: NOT_YET_RECRUITING
Conditions: Insulin Resistance|Polycystic Ovary Syndrome|Hyperinsulinism|Obesity|Metabolic Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound in Evaluating Muscle-Glycogen Content in Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Cachexia|Malignant Solid Neoplasm
Interventions: PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration|PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Therapeutic Effect of the Natural Mineral Water of the Well B-308 OKK in Győr (Gyirmót) on Knee Osteoarthrosis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: medicinal water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT