pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Oral Vitamin D Supplements on Fusion Outcome in Patients Receiving Elective Lumbar Spinal Fusion
Status: COMPLETED
Conditions: Vitamin D|Spinal Fusion|Lumbar Spine Disease
Interventions: DIETARY_SUPPLEMENT: vitamin D3|DIETARY_SUPPLEMENT: calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Pharmacokinetics Study of MLN0128 as a Single Agent and in Combination With Paclitaxel in Adults With Advanced Nonhematologic Malignancies
Status: COMPLETED
Conditions: Non-hematologic Malignancy
Interventions: DRUG: Sapanisertib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Relief of Dry Eye Symptoms With the Use of TheraTears® Products (DUNLIN)
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: TheraTears® Lubricant Eye Drop|DRUG: TheraTears® preservative-free single-use containers|DIETARY_SUPPLEMENT: TheraTears® Nutrition|OTHER: TheraTears® TheraLid® Eyelid Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the BD Onclarity™ HPV Assay on the BD Viper™ LT System With Cervical Specimens
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: DEVICE: BD Onclarity™ HPV assay on BD Viper™ LT|PROCEDURE: Colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RO4607381 in Patients With Coronary Heart Disease (CHD) or a CHD Risk Equivalent.
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: Placebo|DRUG: dalcetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Symptomatic Effects of Nocturnal Sodium Oxybate in Parkinson's Disease
Status: COMPLETED
Conditions: Sleep-wake Disturbances in Motor-phase Parkinson's Disease
Interventions: DRUG: Sodium Oxybate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 Vaccine
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK Biologicals' candidate Plasmodium falciparum malaria vaccine 257049|BIOLOGICAL: Engerix™-B|BIOLOGICAL: Hiberix®|BIOLOGICAL: Prevnar™|DRUG: sulfadoxine-pyrimethamine|DRUG: amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Traumatologic Acute Pain Management With Fentanyl Transdermal Therapeutic System (TTS)
Status: COMPLETED
Conditions: Hip Fractures (ICD-10 72.01-72.2)
Interventions: DRUG: Fentanyl Transdermal System|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients
Status: RECRUITING
Conditions: Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Daunorubicin Hydrochloride|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Long-term Evaluation of Glucosamine Sulphate Study
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Glucosamine sulphate and chondroitin|DIETARY_SUPPLEMENT: Glucosamine sulphate|DIETARY_SUPPLEMENT: Chondroitin sulphate|DIETARY_SUPPLEMENT: Placebo capsules for glucosamine and chondroitin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-121/TEZ/D-IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled, Double-Blind Study to Assess Safety and Efficacy of PCN-101 in TRD
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DRUG: PCN-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated Bilateral rTMS on Geriatric Depression
Status: TERMINATED
Conditions: Transcranial Magnetic Stimulation|Depressive Disorder, Major
Interventions: DEVICE: Repeated Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients
Status: UNKNOWN
Conditions: Meibomian Gland Massage is Important to Delay the Development of Meibomian Gland Dysfunction
Interventions: DRUG: Benoxyl
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Drug Omega 3|DRUG: Drug Omega-3 Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Joint Injections for Osteoarthritic Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Dextrose Prolotherapy|PROCEDURE: Saline Prolotherapy|OTHER: At-home physical therapy exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Dexibuprofen Syrup
Status: COMPLETED
Conditions: Fever|Respiratory Tract Infection
Interventions: DRUG: Dexibuprofen|DRUG: Dexibuprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluoxetine Mitigation Mental Health Study for Patients With Musculoskeletal Trauma
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Injury
Interventions: DRUG: Fluoxetine|DRUG: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles Infusion Treatment for ARDS
Status: WITHDRAWN
Conditions: ARDS, Human
Interventions: DRUG: Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicles|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Onion Peel Extract on Endothelial Function
Status: COMPLETED
Conditions: Healthy|Overweight|Obese
Interventions: DRUG: Placebo|DRUG: Onion peel extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prosthetic Smart Socket Technology to Improve Patient Interaction, Usability, Comfort, Fit, and Function.
Status: UNKNOWN
Conditions: Complications of the Amputated Limb
Interventions: DEVICE: Prosthetic smart socket technology with patient prompting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Plasma Exchange (PLEX) and Convalescent Plasma (CCP) in COVID-19 Patients With Multiorgan Failure
Status: UNKNOWN
Conditions: Respiratory Failure|Renal Failure, Acute
Interventions: PROCEDURE: Plasma exchange and convalescent plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Therapy With Autologous Cytokine-induced Killer Cells for Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: BIOLOGICAL: Autologous cytokine-induced killer cell|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Moderate-dose Hypofractionated RT Combined With Pembrolizumab for HCC With Diffuse Tumor Thrombosis
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Radiotherapy|Pembrolizumab|Tumor Thrombosis
Interventions: RADIATION: Moderate-dose Hypofractionated Intensity-modulated Radiotherapy|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid in Radical Resection and Endoprosthetic Reconstruction
Status: COMPLETED
Conditions: Musculoskeletal Cancer|Sarcoma,Soft Tissue
Interventions: DRUG: Tranexamic Acid (TXA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Treatment in Lupus Nephritis
Status: WITHDRAWN
Conditions: Lupus Nephritis
Interventions: DRUG: cyclosporine +mycophenolic acid+prednison|DRUG: Mycophenolic Acid + prednison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Mechanisms of Psychosocial Aspects of Acupuncture Therapy
Status: RECRUITING
Conditions: Physician-patient Relationship|Fibromyalgia|Acupuncture Therapy
Interventions: DEVICE: Electroacupuncture Analgesia|DEVICE: Hokanson Rapid Cuff Inflator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Bracketing|DRUG: Neoadjuvant therapy|PROCEDURE: Post-treatment volume margin resection|PROCEDURE: Pre-treatment volume margin resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Ocular Demodicosis by Cleansing the Eyelid Margins Combined With Tea Tree Oil Ointment
Status: UNKNOWN
Conditions: Mite-Borne
Interventions: OTHER: cleansing the eyelid margins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Methylphenidate Hydrochloride on Pain and Auditory Sensitivity in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacological Action (PA)
Interventions: DRUG: methylphenidate hydrochloride|DRUG: Sugar pill (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Elution in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Replacement
Interventions: DRUG: hand mixed vancomycin|DRUG: hand mixed tobramycin|DEVICE: pre-mixed tobramycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Total Intravenous Anesthesia With Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Robot-assisted Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Robotic Radical Prostatectomy
Interventions: DRUG: Propofol anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bone Loss, Alveolar
Interventions: DEVICE: Zimmer T3 Short Ex Hex With Discrete Crystalline Deposition|DEVICE: Zimmer T3 with DCD Ex Hex Parallel Walled implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Manual Cervical Traction and Natural Apophyseal Glides for Cervical Radiculopathy Patients
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Natural apophyseal glides|OTHER: Cervical manual traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating SINE KPT-330 in Treating Patients With Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma
Interventions: DRUG: selinexor|OTHER: Correlative studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignancies|NSCLC|Ovarian Cancer|Urothelial Cancer|Solid Tumors
Interventions: DRUG: Avelumab|DRUG: Lorlatanib|DRUG: Talazoparib|DRUG: Pemetrexed|DRUG: Axitinib|DRUG: CMP 001|DRUG: Utomilumab|DRUG: PF04518600
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin|DRUG: Metformin HCl|DRUG: Alogliptin and Metformin Fixed-Dose Combination (FDC)|DRUG: Alogliptin Placebo|DRUG: Metformin Placebo|DRUG: Alogliptin and Metformin FDC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR1701 Plus Chemotherapy in Patients With Gastric or Gastroesophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric or Gastroesophageal Junction Cancer
Interventions: DRUG: SHR-1701、CAPOX|DRUG: Placebo、CAPOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Carvedilol Tablets 12.5 mg to Coreg® Tablets 12.5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol Tablets 12.5 mg|DRUG: Coreg® Tablets 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy|Pain
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX Plus PF-04136309 in Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: Fluorouracil|OTHER: laboratory biomarker analysis|OTHER: flow cytometry|OTHER: immunohistochemistry staining method|OTHER: pharmacological study|DRUG: PF-04136309
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Indomethacin in Monosymptomatic Enuresis Nocturnal
Status: COMPLETED
Conditions: Enuresis
Interventions: DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TENS and Orthognathic Surgery
Status: RECRUITING
Conditions: Orthognathic Surgery
Interventions: BEHAVIORAL: TENS|BEHAVIORAL: sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women
Status: UNKNOWN
Conditions: Dyspareunia|Menopause|Sexual Dysfunction
Interventions: DRUG: Estriol|DRUG: Distal estriol|DRUG: Vaginal Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ABG+/GarlACE Effects on Cardiovascular Risk Factors in Subjects With Grade I Hypertension
Status: RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Low dose|DIETARY_SUPPLEMENT: High dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Image -Guided Stereotactic Radiation Therapy (IG-SRT) in Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DEVICE: Endorectal Balloon|DEVICE: Rectal Spacer|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Intervention Program Based on Motivational Interview
Status: RECRUITING
Conditions: Periodontitis|Periodontal Diseases|Motivational Interviewing
Interventions: BEHAVIORAL: Motivational Interview Group (MIG)|PROCEDURE: Conventional treatment group (CTG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Effects of a Holistic Yoga Program and a Wellness Program on PTSD Symptoms
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Holistic Yoga Program|BEHAVIORAL: Wellness Lifestyle Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alvimopan For The Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Status: COMPLETED
Conditions: Bowel Dysfunction|Constipation
Interventions: DRUG: Placebo|DRUG: Alvimopan|DRUG: Alviompan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Budesonide Inhalation on Arterial Blood Oxygenation and Intrapulmonary Shunt During OLV
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: preoperative budesonide inhalation|DRUG: preoperative normal saline inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Investigation of the Quality of Life Benefit of Using a Home Walking Exoskeleton for a Population of Multiple Sclerosis Patients.
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: Keeogo|OTHER: adviced home practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study Between Three Different Plating Techniques in Management of Mandibular Parasymphyseal Fractures.
Status: COMPLETED
Conditions: Mandibular Fractures
Interventions: DEVICE: 2.0 miniplates|DEVICE: 2.3 high profile miniplates|DEVICE: 3D miniplates
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An European Union (EU) Post-Approval Registry of the TREO® Stent-Graft
Status: TERMINATED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: TREO Stent-Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Vaccine Trial for Patients With Stage IIIB, IV, or Recurrent Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: BIOLOGICAL: autologous dendritic cell adenovirus CCL21 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: Toripalimab, pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Follicular Lymphoma|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Refractory Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Small Lymphocytic Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-irradiation With Fractionated Stereotactic Radiosurgery Plus Cetuximab in Patients With Recurrent Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Cetuximab|DEVICE: Stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong
Status: RECRUITING
Conditions: Depressive Symptoms
Interventions: BEHAVIORAL: Smartphone-based Daily Ecological Momentary Intervention|BEHAVIORAL: Smartphone-based Weekly-delivered Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine,Cyclophosphamide and Rituximab Followed by Zevalin for Non-Follicular Indolent Lymphomas.
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients
Status: UNKNOWN
Conditions: ph+ Acute Lymphoblastic Leukemia
Interventions: DRUG: Dasatinib|DRUG: prednisone|DRUG: dexamethasone|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Versus No Surgery for Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: PROCEDURE: Arthroscopic surgery|OTHER: Physical and medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remotely Supervised Transcranial Direct Current Stimulation (tDCS) for Primary Progressive Aphasia (PPA)
Status: COMPLETED
Conditions: Primary Progressive Aphasia
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|BEHAVIORAL: Word-Naming Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Evolocumab (AMG 145) in Adults With Hyperlipidemia on Stable Doses of a Statin
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial
Status: COMPLETED
Conditions: Respiratory Failure|Respiratory Failure With Hypoxia|Endotracheal Intubation
Interventions: OTHER: Manual Ventilation|OTHER: No Manual Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Trial on the Effect of Elotuzumab in VRD Induction /Consolidation and Lenalidomide Maintenance in Patients With Newly Diagnosed Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: elotuzumab|DRUG: Lenalidomide|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Cilostazol Loading in Elective Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Pentoxifylline at Improving Blood Vessel Function in HIV-infected People Not Receiving Antiretroviral Medications
Status: COMPLETED
Conditions: HIV|Cardiovascular Diseases|Atherosclerosis
Interventions: DRUG: Pentoxifylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OASIS: Peer Support for T2DM in Appalachia (Peer Participant)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Peer Coach Training - Weekly|BEHAVIORAL: Peer Coach Training - Biweekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Energy Intake, Exercise and Energy Replacement
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: CON . control condition without exercise / rest condition|BEHAVIORAL: EX. Condition with an acute exercise set in the middle of the morning|BEHAVIORAL: EX+R. condition with an acute exercise set in the morning and followed by a energy replacement snack
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Atrial Fibrillation by Low-dose Landiolol Administration After Cardiac Surgery
Status: COMPLETED
Conditions: Atrial Fibrillation|Cardiac Surgery
Interventions: DRUG: Landiolol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Early Manual Therapy on Functional Outcomes After Volar Plating of Distal Radius Fractures
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: OTHER: Early Manual Therapy|OTHER: Routine Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Semirigid Cervical Collar and Nasotracheal Intubation by Glidescope in Cervical Spine Surgery
Status: COMPLETED
Conditions: Orthosis
Interventions: DEVICE: Miami cervical collar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses
Status: COMPLETED
Conditions: Contact Lens Base Curve (BC) Fit and Comfort
Interventions: DEVICE: Contact Lenses with 8.5 BC|DEVICE: Contact Lenses with 9.0 BC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Topical Diclofenac and Topical DFMO Chemoprevention Trial in Subjects With a History of Skin Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-melanoma Skin Cancer
Interventions: DRUG: Solaraze and Vaniqa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood Loss
Status: UNKNOWN
Conditions: Menorrhagia
Interventions: DRUG: Tranexamic Acid 500 MG|DRUG: Calcium Dobesilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of ADVATE Reconstituted in 2 mL Sterile Water for Injection
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Antihemophilic factor, recombinant, manufactured protein-free (rAHF-PFM). (Antihemophilic factor is also known as Factor VIII)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vigamox Treatment for Ocular Graft-Versus-Host Disease
Status: WITHDRAWN
Conditions: Ocular Graft-versus-host Disease
Interventions: DRUG: Vigamox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Pulse Field Ablation System for the Treatment of Paroxysmal Atrial Fibrillation in 11 Centers in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Pulse ablation catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of H-FICB ＆ PENG Block in Elderly Patients' THA on the Post-operative Quality of Recovery
Status: UNKNOWN
Conditions: Nerve Block|Quality of Recovery
Interventions: PROCEDURE: ultrasound-guided high fascia iliaca compartment block|PROCEDURE: ultrasound-guided pericapsular nerve group (PENG) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Plus Combination Chemotherapy in Treating Patients With Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: etoposide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized tDCS for the Treatment of Migraine
Status: UNKNOWN
Conditions: Migraine Disorders
Interventions: PROCEDURE: anodal tDCS on M1|PROCEDURE: cathodal tDCS on M1|PROCEDURE: anodal tDCS on V1|PROCEDURE: cathodal tDCS on V1|PROCEDURE: anodal tDCS on M1 and cathodal on V1|PROCEDURE: cathodal tDCS on M1 and anodal on V1|PROCEDURE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intralipid® 20% for Reversal of Local Anesthetics
Status: RECRUITING
Conditions: Anesthesia, Local
Interventions: DRUG: Lidocaine 2%|DRUG: Lidocaine 1%|DRUG: Bupivacaine 0.25%|DRUG: Bupivacaine 0.5%|DRUG: Intralipid, 20% Intravenous|OTHER: Saline intravenously|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: SUN-101 50 mcg BID eFlow (CS) nebulizer|DRUG: Spiriva® 18 mcg QD Handihaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration and Activity of Lapatinib in Vestibular Schwannomas
Status: COMPLETED
Conditions: Vestibular Schwannoma|NF2|Neurofibromatosis 2|Acoustic Neuroma|Auditory Tumor
Interventions: DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Pomegranate Extract on the Microbiome and Skin Biophysical Properties
Status: COMPLETED
Conditions: Human Microbiome
Interventions: DIETARY_SUPPLEMENT: Pomella|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Serratus Posterior Superior Interfascial Plane Block for Thoracoscopic Surgery
Status: WITHDRAWN
Conditions: Lung Diseases
Interventions: DRUG: Analgesia management; group S and C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics in Prevention of Spontaneous Bacterial Peritonitis in Compensated Liver Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis|Upper Gastrointestinal Bleeding
Interventions: DRUG: Third generation cephalosporin antibiotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensification With Enfuvirtide in Naive HIV-infected Patients (ANRS130)
Status: COMPLETED
Conditions: HIV Infections|AIDS
Interventions: DRUG: enfuvirtide|DRUG: emtricitabine/tenofovir|DRUG: lopinavir or efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Optimised Use of Romozosumab Study
Status: RECRUITING
Conditions: Osteoporosis
Interventions: DRUG: Romosozumab|DRUG: Zoledronate|DRUG: Romosozumab|DRUG: Zoledronate|DRUG: Romosozumab|DRUG: Zoledronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of 6% HES130/0.4
Status: COMPLETED
Conditions: Hypovolemia|Hemorrhage
Interventions: DRUG: 6% hydroxyethyl starch 130/0.4|DRUG: 6% hydroxyethyl starch 70/0.5 (Salinhes®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Bone Marrow Transplant in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Multiple Myeloma and Malignant Plasma Cell Neoplasms|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: cyclophosphamide|RADIATION: TBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating Compatibility and Safety of FIAsp and Insulin Aspart With an External Continuous Subcutaneous Insulin Infusion System in Adult Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Faster-acting insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Safety of FlutiForm® pMDI 125/5 µg (2 Puffs Bid) Versus Symbicort® Turbohaler® 200/6 µg (2 Puffs Bid) in Adolescent and Adult Subjects With Moderate to Severe Persistent, Reversible Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Flutiform|DRUG: Symbicort Turbohaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Compare the Clinical Outcomes, Pain and Patient Quality of Life for Hernia Patients
Status: COMPLETED
Conditions: Hernia|Incisional Hernia|Hernia, Inguinal, Indirect|Hernia, Inguinal, Direct|Inguinal Hernia
Interventions: PROCEDURE: Hernia repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Night Owl Metabolism
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes|Overweight|Impaired Glucose Tolerance
Interventions: DIAGNOSTIC_TEST: Timing of OGTT|BEHAVIORAL: Timing of Standardized Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies
Status: TERMINATED
Conditions: Lymphoma, B-Cell|Chronic Lymphocytic Leukemia
Interventions: DRUG: FT596|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab|DRUG: Obinutuzumab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Stimulant Medication on Brain Processes for Decision Making in Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit-Hyperactivity Disorder
Interventions: DRUG: Ritalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DN24-02 as Adjuvant Therapy in Subjects With High Risk HER2+ Urothelial Carcinoma
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: DN24-02|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults
Status: RECRUITING
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: DRUG: T2026|DRUG: Placebo|DRUG: Oral ecnoglutide tablet|DRUG: Oral ecnoglutide tablet|DRUG: Oral ecnoglutide tablet|DRUG: Oral ecnoglutide tablet|DRUG: Oral ecnoglutide tablet|DRUG: Oral ecnoglutide tablet|DRUG: T2026|DRUG: Placebo|DRUG: T2026|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Neuroprotection in Pediatric Cardiac Surgery
Status: UNKNOWN
Conditions: Congenital Heart Disease
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Predicting Treatment Outcomes in Refractory Constipation Through Brain Connectivity Evaluation
Status: RECRUITING
Conditions: Constipation - Functional|Refractory Constipation|Fluoxetine|fMRI|Brain Connectivity|Treatment Efficacy|Somatic Symptom|Mental Symptom
Interventions: DIAGNOSTIC_TEST: BOLD-fMRI|DRUG: Regular treatment of functional constipation|DRUG: fluoxetine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of PENNSAID® for Pain Management in the Emergency Department
Status: WITHDRAWN
Conditions: Pain|Ankle Sprain
Interventions: DRUG: PENNSAID|DRUG: Diclofenac hydroxyethylpyrrolidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prolonged Exposure Therapy for PTSD and Opioid Use Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Opioid-use Disorder
Interventions: BEHAVIORAL: Prolonged Exposure Therapy|BEHAVIORAL: Attendance-based monetary incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Proactive Telephone Follow-up With Patients After Completion of Primary Cancer Treatment
Status: RECRUITING
Conditions: Breast Cancer|Colorectal Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Proactive nurse-led telephone follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic One Anastomosis Gastric Bypass
Status: ACTIVE_NOT_RECRUITING
Conditions: Morbid Obesity|Postoperative Complications|Weight Loss
Interventions: PROCEDURE: Minigastric bypass|PROCEDURE: Gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess Single Dosage Strength Of GW685698/GW642444 Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW685698/GW642444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: HVPG-Guided Therapy vs Carvedilol Plus Endotherapy for the Prevention of Esophageal Variceal Rebleeding in Cirrhotic Patients
Status: UNKNOWN
Conditions: Liver Cirrhoses|Variceal Hemorrhage|Esophageal Varices
Interventions: PROCEDURE: Transjugular intrahepatic portosystemic shunt|DRUG: Carvedilol|PROCEDURE: Endoscopic variceal ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention Inhalation of Bacterial by Using Endotracheal Tube Balloon Polyvinyl Chloride or Polyurethane
Status: COMPLETED
Conditions: Acute Respiratory Failure|Mechanical Ventilation Complication
Interventions: DEVICE: Experimental 1|DEVICE: Experimental|DEVICE: experimental 3|DEVICE: Active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Versus Antibiotics in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: 3D Analysis of the Effects of tDCS (Transcranial Direct Current Stimulation) on a Functional Task in High Level Athletes
Status: COMPLETED
Conditions: Healthy|Athlete
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diet and Learning Abilities in Norwegian Youths
Status: COMPLETED
Conditions: Cognitive Performance|Health Behavior|Nutrient Status
Interventions: OTHER: Schoolmeal with fatty fish|OTHER: Schoolmeal without fish|DIETARY_SUPPLEMENT: Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clinical Benefits of a Blood Glucose Monitoring System in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: OneTouch® Ultra®2 System|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training
Status: COMPLETED
Conditions: Congenital Heart Disease|Single Ventricle
Interventions: DEVICE: THRESHOLD(TM) INSPIRATORY MUSCLE TRAINER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Bioequivalence Study Between Amphotericin B Liposome for Injection and AmBisome® in Healthy Subjects
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Amphotericin B liposome for injection|DRUG: AmBisome®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Citrate 4% Versus Heparinised Saline in Preventing Peripherally Inserted Central Catheter (PICC) Occlusions
Status: UNKNOWN
Conditions: Occlusion
Interventions: DRUG: Citrate 4%|DRUG: Heparinised saline (10U/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate Multiple Ascending Doses of AZD5004 in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: AZD5004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Carbohydrate on Serum S-100β Protein and Development of Postoperative Delirium in Elderly Patients
Status: COMPLETED
Conditions: Insulin Resistance|Inflammation|Delirium
Interventions: DIETARY_SUPPLEMENT: Allocated to Carbohydrated group|DIETARY_SUPPLEMENT: Allocated to Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inhaled Tacrolimus, Add-on to Inhaled Corticosteroids & Long Acting B2 Agonists in Moderate to Severe Persistent Asthma
Status: COMPLETED
Conditions: Asthma, Bronchial|Bronchial Asthma
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT