pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Peer to Community (P2C) Model: A Pilot Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Social Inclusion|Mental Illness|Substance Use Disorders
Interventions: BEHAVIORAL: Peer to Community (P2C) Model|BEHAVIORAL: Care as Usual (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Photobiomodulation Using LED Lamp for Curative Treatment of Radio-induced Mucositis.
Status: COMPLETED
Conditions: Oral Cancer|Oropharyngeal Cancer
Interventions: PROCEDURE: LED photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NC Testing in LC & POTS
Status: NOT_YET_RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome|Post Acute Sequelae of SARS CoV 2 Infection
Interventions: OTHER: IV normal saline (999 mL infusion)|OTHER: IV normal saline (50 mL infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histerectomy Vs Partial Myometrial Resection for Placenta Accreta Spectrum
Status: COMPLETED
Conditions: Placenta Accreta
Interventions: PROCEDURE: Hysterectomy|PROCEDURE: Partial Myometrial Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Carvedilol 12.5 mg Tablets Under Non-fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol 12.5 mg Tablets, single dose|DRUG: Coreg® 12.5 mg Tablets , single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNH
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Danicopan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlating Improvement in PCOS Symptoms to the Percentage of Body Weight Lost in Females Also Living With Obesity
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary Syndrome|Obesity
Interventions: BEHAVIORAL: STREAM program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Riluzole in Hereditary Cerebellar Ataxia
Status: COMPLETED
Conditions: Cerebellar Ataxia
Interventions: DRUG: riluzole|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Diaphragm Muscle Thickness and Fibromyalgia
Status: RECRUITING
Conditions: Fibromyalgia|Anxiety|Depression|Diaphragm Issues
Interventions: DIAGNOSTIC_TEST: Fibromyalgia study form|DIAGNOSTIC_TEST: Pulmonary function test|DIAGNOSTIC_TEST: Ultrasonographic Diaphragm Thickness Measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vortioxetine (Lu AA21004) 10 and 20 mg for Treatment of Major Depressive Disorder With Sexual Dysfunction
Status: COMPLETED
Conditions: Treatment Outcome
Interventions: DRUG: Vortioxetine|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of VX-210 in Subjects With Acute Traumatic Cervical Spinal Cord Injury
Status: TERMINATED
Conditions: Cervical Spinal Cord Injury
Interventions: DRUG: VX-210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-005)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: Opevesostat|DRUG: Dexamethasone|DRUG: Fludrocortisone acetate|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Comparison of Two New Bronchial Blockers vs. Double Lumen Tubes in One Lung Ventilation
Status: COMPLETED
Conditions: Thoracic Surgery, Lung Isolation
Interventions: DEVICE: Double lumen tube|DEVICE: Fuji blocker|DEVICE: EZ blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of SPD489 in Combination With an Antidepressant in the Treatment of Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: SPD489 (Lisdexamfetamine dimesylate )|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic and Safety Study of BCS in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Benzalkonium Chloride Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of N-Acetylcysteine on Neutrophil Lymphocyte Ratio And Length of Stay In COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eye-Control Trial: Wearable Eye-Tracking Device as Means of Communication
Status: COMPLETED
Conditions: Acute Respiratory Failure Requiring Mechanical Ventilation
Interventions: DEVICE: EyeControl Eye-tracking Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss
Status: COMPLETED
Conditions: Hearing Loss|Ear Diseases|Hearing Disorders|Otorhinolaryngologic Diseases|Asymmetrical Hearing Loss|Single-Sided Deafness
Interventions: DEVICE: HiResolution Bionic Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: iCorMicA - Stratified Medicine in Angina
Status: RECRUITING
Conditions: Microvascular Angina|Angina, Stable|Ischemia With No Obstructive Coronary Arteries (INOCA)|Coronary Microvascular Dysfunction (CMD)|Ischaemic Heart Disease|Non-Obstructive Coronary Atherosclerosis|Coronary Artery Disease|Vasospastic Angina|Coronary; Ischemic|Angina Attacks
Interventions: DIAGNOSTIC_TEST: Disclosure of IDP results|OTHER: IDP performed but results not disclosed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Preventing Recurrent UTI With Vaginal Estrogen
Status: ENROLLING_BY_INVITATION
Conditions: Recurrent Urinary Tract Infection|Urinary Tract Infections|Cystitis Recurrent
Interventions: DRUG: Vaginal estradiol tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: French Assessment of MRD by Liquid Biopsies in PDAC Patients (FRENCH.MRD.PDAC)
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer Resectable|Pancreatic Ductal Adenocarcinoma|Minimal Residual Disease|Liquid Biopsy|ctDNA
Interventions: BIOLOGICAL: Blood sample/Liquid Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tonsil Surgery in Recurrent or Chronic Tonsillitis
Status: COMPLETED
Conditions: Tonsillitis Recurrent|Tonsillitis Chronic
Interventions: PROCEDURE: Tonsillectomy|PROCEDURE: Tonsillotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Multiple Myeloma|Myelodysplastic Syndrome|Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Palifermin|BIOLOGICAL: Lupron|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: Total-Body Irradiation (TBI)|DRUG: Thiotepa|DRUG: Cyclophosphamide|DRUG: Degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Veil Preserving HoLEP vs. Stanadard HoLEP
Status: COMPLETED
Conditions: Post Prostatectomy Incontinence
Interventions: PROCEDURE: Veil sparring HoLEP|PROCEDURE: Standard HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
Status: COMPLETED
Conditions: Diabetes|Heart Failure
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking Into Blood Levels of NNC0174-0833 in People With Normal and Impaired Kidney Function
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: NNC0174-0833
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination
Status: TERMINATED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Brinzolamide 1%/brimonidine tartrate 0.2% ophthalmic suspension|DRUG: Brinzolamide ophthalmic suspension, 1%|DRUG: Brimonidine tartrate ophthalmic solution, 0.2%|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic Dysarthria
Interventions: DEVICE: Vibro Tactile Gadget
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation
Status: WITHDRAWN
Conditions: Tooth Loss
Interventions: OTHER: Particulate bone graft|OTHER: Autogenous dental pulp tissue|OTHER: Resorbable collagen membrane|OTHER: Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TD-1607 SAD Study in Healthy Subjects
Status: COMPLETED
Conditions: Serious Infections Due to Known or Suspected Gram-positive Pathogens
Interventions: DRUG: TD-1607|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Non Myeloablative (Flu-TBI) and Reduced Intensity (FLU-BU-ATG) Conditioning in Allogenic Transplantation
Status: COMPLETED
Conditions: Allograft|Allogeneic Cell Transplantaion|Hematological Malignancy|Solid Tumor
Interventions: DRUG: reduced intensity conditionings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
Status: COMPLETED
Conditions: Neurofibromatosis Type 2|Vestibular Schwannomas|Meningiomas
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Milnacipran for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Placebo|DRUG: Milnacipran 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Meritup Oral Solution to Decrease Fatigue in Metastatic Breast Cancer Patients Receiving Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: COMBINATION_PRODUCT: Meritup oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
Status: RECRUITING
Conditions: Juxtarenal Aortic Aneurysms|Suprarenal Aortic Aneurysms|Type IV Thoracoabdominal Aortic Aneurysms
Interventions: DEVICE: Custom-made Zenith® Fenestrated AAA Endovascular Graft:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: KRAS G12C Mutant Solid Tumors|Carcinoma, Non-Small Cell Lung|Carcinoma, Non-Small-Cell Lung|Non-Small Cell Lung Cancer|Non-Small Cell Lung Carcinoma|Nonsmall Cell Lung Cancer|Colorectal Cancer|Colorectal Carcinoma|Colorectal Neoplasms|Colorectal Tumors|Neoplasms, Colorectal
Interventions: DRUG: JDQ443|DRUG: trametinib|DRUG: Ribociclib|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of A Computerized Working Memory Training Program On Attention, Working Memory, And Academics, In Adolescents With Severe ADHD/LD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Learning Disorders
Interventions: OTHER: Cogmed Working Memory Training Program.|OTHER: Academy of Math|OTHER: Special Education/Individualized Tutoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Altering Activation Patterns Post-stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Muscle Spasticity|Hemiparesis
Interventions: DRUG: Cyproheptadine|DRUG: Placebo for Cyproheptadine|OTHER: Active Movement Practice (AMP)|OTHER: Passive Cyclical Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Standard Chemotherapy With Trastuzumab, Plus or Minus Pertuzumab, for Pre-treated Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Malignant Tumor of the Breast
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Vinorelbine, Paclitaxel, Nab-Paclitaxel , Docetaxel, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Dental Care Revolution: Health Education Using AI or Humanized Counseling on Plague Control and Periodontal Treatment Outcome in Patients With Periodontal Disease
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: BEHAVIORAL: The AI-assisted tool used in this study was called Dental Monitoring (DM).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of QT and QTc Intervals in Patients Administered Immediate Release Paliperidone
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Immediate release (IR) Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Function in Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivor With History of Anthracycline Chemotherapy
Interventions: DIETARY_SUPPLEMENT: Beetroot juice|DIETARY_SUPPLEMENT: Black currant juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of a Single Dose of REGN5713-5714-5715 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers|Birch Pollen Allergy
Interventions: DRUG: REGN5713-5714-5715|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Status: RECRUITING
Conditions: Healthy Subjects|Stuttering, Developmental
Interventions: BEHAVIORAL: Delaying speech initiation|BEHAVIORAL: Auditory errors and pre-speech auditory modulation|BEHAVIORAL: Contributions of the speech premotor cortex to pre-speech auditory modulation|BEHAVIORAL: Delaying auditory feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV)
Status: WITHDRAWN
Conditions: Cardiac Allograft Vasculopathy
Interventions: DRUG: Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tVNS for Cognitive Impairments in Community-Dwelling Elderly
Status: UNKNOWN
Conditions: Aging
Interventions: DEVICE: Active tVNS|DEVICE: Sham tVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation (tDCS) Enhancement of Trauma-focused Therapy for Posttraumatic Stress Disorder
Status: UNKNOWN
Conditions: Post-traumatic Stress Disorder (PTSD)
Interventions: DEVICE: Trauma Focused Therapy + tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Pharmacokinetic Profiles of Four Extended Release Paracetamol Formulations
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Paracetamol|DRUG: Paracetamol formulation 1|DRUG: Paracetamol Formulation 2|DRUG: Paracetamol formulation 3|DRUG: Paracetamol formulation 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy
Status: COMPLETED
Conditions: Cholangiocarcinoma of the Gallbladder|Localized Gallbladder Cancer|Unresectable Gallbladder Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: everolimus|DRUG: gemcitabine hydrochloride|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Regain of Gastrointestinal Motility After General Anaesthesia Versus Spinal Anaesthesia in Caesarean Section
Status: UNKNOWN
Conditions: G.I.T. Motility After General Versus Spinal Anaesthesia
Interventions: PROCEDURE: general anasthesia,spinal anasthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded NIPT for Pregnancy Complications
Status: ACTIVE_NOT_RECRUITING
Conditions: Fetal Growth Restriction|Preeclampsia Severe
Interventions: GENETIC: Expanded panel cell free DNA testing (non-invasive prenatal testing)|GENETIC: Placental biopsy|GENETIC: Umbilical cord blood
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Matching Cognitive Remediation to Cognitive Deficits in Substance-Abusing Inmates
Status: COMPLETED
Conditions: Psychopathy|Personality Disorders
Interventions: OTHER: Cognitive Remediation|OTHER: Cognitive Remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clonidine in Femoral Nerve Block Surgery in Children
Status: WITHDRAWN
Conditions: Other Reconstructive Surgery
Interventions: DRUG: Ropivacaine|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Keberkesanan Modul Intervensi Berasaskan Sensori Dalam Kalangan Kanak-kanak Dengan Autisme/The Effectiveness of Sensory-based Intervention in Children With Autism Spectrum Disorders.
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Sensory-based intervention module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma
Status: TERMINATED
Conditions: Asthma|Status Asthmaticus
Interventions: DRUG: Dose Group 1|DRUG: MN-221 placebo|DRUG: Dose Group 2|DRUG: Dose Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Surgery With or Without Lymphadenectomy and Radiation Therapy in Treating Patients With Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Positive Changes in Quality of Life of Older Cancer Patients and Their Caregivers
Status: WITHDRAWN
Conditions: Psychosocial Effects of Cancer and Its Treatment|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: questionnaire administration|OTHER: study of socioeconomic and demographic variables|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Immune Thrombocytopenia
Status: RECRUITING
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Orelabrutinib( lower dose)|DRUG: Orelabrutinib( higher dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LGD-6972 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LGD-6972-5 mg|DRUG: LGD-6972-10 mg|DRUG: LGD-6972-15 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Cancer Stem Cell High-Throughput Drug Screening for Glioblastoma
Status: RECRUITING
Conditions: Newly Diagnosed Glioblastoma
Interventions: DRUG: combinations of up to 3 FDA approved drugs from a panel of compounds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Bevacizumab With FOLFOX or FOLFIRI.
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: PROCEDURE: Metastases resection|DRUG: Bevacizumab|DRUG: 5 FU|DRUG: Oxaliplatin|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia
Status: RECRUITING
Conditions: Respiratory Infection|Pneumonia|Community-acquired Pneumonia|Acute Respiratory Distress Syndrome|COVID-19|Viral Pneumonia|Bacterial Pneumonia|Fungal Pneumonia
Interventions: DRUG: Trimodulin|DRUG: Placebo (human albumin 1%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous (IV) AMD3100 for Mobilization and Matched Related Transplant for Advanced Hematological Malignancies
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: DRUG: AMD3100|PROCEDURE: Leukopheresis|PROCEDURE: Stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Ketogenic Diet on Acute Stroke
Status: COMPLETED
Conditions: Acute Stroke
Interventions: DIETARY_SUPPLEMENT: Ketocal 4:1 (Nutricia)|DIETARY_SUPPLEMENT: Control diet: Regular diet offered at the hospitals|DIETARY_SUPPLEMENT: Ketogenic meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e- Ab Sensor - Based Real-time Diagnosis of Enterovirus Type 71
Status: UNKNOWN
Conditions: EV71
Interventions: DEVICE: Electrosensing antibody probing system (e- Ab sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study of Combined Radical Operation With Postoperative Adjuvant Chemotherapy and Prophylactic Cranial Irradiation in pT1-2N0M0 Stage of Small Cell Lung Cancer
Status: RECRUITING
Conditions: Small-cell Lung Cancer
Interventions: PROCEDURE: prophylactic cranial irradiation (PCI)|PROCEDURE: lobectomy + mediastinal lymph node dissection or systematic lymph node sampling|DRUG: postoperative adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: M3-JIA: Making Mindfulness Matter for Children With JIA
Status: NOT_YET_RECRUITING
Conditions: Juvenile Idiopathic Arthritis|Children|Mental Health|Mental Well-being
Interventions: BEHAVIORAL: M3 Intervention group|BEHAVIORAL: M3 Waitlist Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Colorectal Cancer|Neuropathy|Neurotoxicity
Interventions: DRUG: calcium gluconate|DRUG: magnesium sulfate|OTHER: placebo|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor, Adult|Breast Cancer|Non Small Cell Lung Cancer|Head and Neck Cancer|Ovarian Cancer
Interventions: DRUG: CX-2009
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy in Patients With Myocardial Infarction and Persistent Total Occlusion of Infarct Related Artery
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Intracoronary stem cells injection|PROCEDURE: coronary dilatation and stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Multiple Doses of BIIL 284 BS on the Pharmacokinetics of Prednisone in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIL 284 BS|DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-HIV Cellular Therapy Based on Dendritic Cells Pulsed With Chemically Inactivated Virus
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: DC|BIOLOGICAL: DC10e6+HIV-AT2|BIOLOGICAL: DC10e7+HIV-AT2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Ixabepilone|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCH 54031 PEG12000 Interferon Alfa-2b (PEG Intron, MK-4031) vs. INTRON®A (SCH 30500, MK-2958) as Adjuvant Therapy for Melanoma (C98-135, MK-4031-002)
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: PEG-Intron|BIOLOGICAL: INTRON A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation to Treat Patients With Heart Failure With Preserved Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Normal Ejection Fraction
Interventions: DEVICE: low level transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Trial of the Recombinant Zoster Vaccine （CHO Cell）, LYB004 in Adults Aged 50 to 70 Years
Status: RECRUITING
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: LYB004 25µg|BIOLOGICAL: LYB004 50µg|BIOLOGICAL: SHINGRIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of 28431754 (Canagliflozin) on Gastrointestinal Glucose Absorption and Metabolism in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin/Placebo Placebo/Canagliflozin|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: NEURESCUE Device as an Adjunct to In-Hospital Cardiac Arrest (ARISE)
Status: RECRUITING
Conditions: Cardiac Arrest|Cardiopulmonary Arrest|Cardiovascular Diseases
Interventions: DEVICE: NEURESCUE device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin solution 100 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: RESOLUTE ONYX Post-Approval Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System|DEVICE: Resolute Onyx™ Zotarolimus-Eluting Coronary Stent System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
Status: RECRUITING
Conditions: Leukemia
Interventions: DRUG: Cytarabine|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Me-CCNU|DRUG: Rabbit antithymocyte globulin|PROCEDURE: Allogeneic HSCT|DRUG: Cyclosporin A|DRUG: Mycophenolate Mofetil|DRUG: MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Arthrocentesis and Occlusal Splint Therapy for Closed Locks of the TMJ
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Arthrocentesis of the temporomandibular joint
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf® Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.
Status: NOT_YET_RECRUITING
Conditions: Kidney Transplantation|Mycophenolate Mofetil
Interventions: DRUG: Mycophenolate Mofetil (MMF) Maintenance Group|DRUG: Mycophenolate Mofetil (MMF) Withdrawal Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Centanafadine SR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining rTMS and Video Game-based Dexterity Training to Improve Dexterity in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Transcranial magnetic stimulation|OTHER: Sham transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Acetaminophen|DRUG: Bupivacain|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Cognitive Effects of Electroconvulsive Therapy Via Machine Learning and Neuroimaging
Status: UNKNOWN
Conditions: ECT|Depression|Cognitive Impairment|Memory Impairment
Interventions: DEVICE: Electroconvulsive Therapy|DRUG: Medication - Treatment as usual
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobile Microwave-based Diagnosis and Monitoring of Stroke
Status: RECRUITING
Conditions: Stroke, Acute|Intracerebral Hemorrhage
Interventions: DIAGNOSTIC_TEST: Hemorrhagic stroke group (group A)|DIAGNOSTIC_TEST: Ischemic stroke group (group B)|DIAGNOSTIC_TEST: Stroke mimic group (group C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Gene Transfer Study for Late-Onset Pompe Disease (RESOLUTE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pompe Disease|Pompe Disease (Late-onset)|Glycogen Storage Disease Type 2|Glycogen Storage Disease Type II|LOPD|Lysosomal Storage Diseases|Acid Maltase Deficiency
Interventions: GENETIC: SPK-3006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Torsemide Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: To Determine Bioequivalence Under Fasting Conditions
Interventions: DRUG: Torsemide|DRUG: Demadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Echocardiography Based Algorithm for Spinal Anaesthesia
Status: UNKNOWN
Conditions: Hypotension
Interventions: DEVICE: Echocardiography|DEVICE: Treatment of spinal hypotension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Labor Induction and Maternal BMI, Comparison of Different Pre-induction Cervical Ripening Methods
Status: UNKNOWN
Conditions: Obesity|Labor Complications
Interventions: DEVICE: Cook double balloon catheter|DRUG: PGE1 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Progressive Exercise on Shoulder Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Shoulder Impingement|Tendinopathy
Interventions: OTHER: Neuromuscular resistance exercise program|OTHER: Control exercise program with elastic band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Study of Intravitreal Aflibercept, Bevacizumab, and Ranibizumab for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: 2.0 mg intravitreal aflibercept|DRUG: 1.25 mg intravitreal bevacizumab|DRUG: 0.3 mg intravitreal ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Triamcinolone Acetonide Mucoadhesive Films With Licorice Mucoadhesive Films
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: Triamcinolone Acetonide|DRUG: licorice mucoadhesive films
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)
Status: RECRUITING
Conditions: Sickle Cell Disease|Hydroxyurea Failure|Hydroxyurea Intolerance|Hemoglobinopathies|Hematological Diseases
Interventions: BIOLOGICAL: CTX001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: International Study to Predict Optimised Treatment - in Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Sertraline|DRUG: Venlafaxine-XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Fosaprepitant Dimeglumine in Preventing Chemotherapy-Induced Nausea and Vomiting (MK-0517-031)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting (CINV)
Interventions: DRUG: Fosaprepitant dimeglumine|DRUG: Fosaprepitant Placebo|DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: Dexamethasone Placebo|DRUG: Ondansetron Placebo|DRUG: Rescue Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Physical Evaluation|DIAGNOSTIC_TEST: Dual-energy X-ray absorptiometry scans|DIAGNOSTIC_TEST: Trabecular Bone Score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC)
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis|Trisomy 7|Cholangiocarcinoma|Chemoprevention
Interventions: DRUG: Erlotinib (Tarceva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of SP-8203 in Patients With Ischemic Stroke Requiring rtPA
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: SP-8203|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of EPI-743 for Treatment of Rett Syndrome
Status: COMPLETED
Conditions: Rett Syndrome
Interventions: DRUG: EPI-743|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Results of Heart Bypass Surgery Using New Approaches to Surgery and Medication
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: No-touch SVG harvest vs conventional SVG harvest technique|DIETARY_SUPPLEMENT: Fish oil supplementation vs placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression
Status: TERMINATED
Conditions: Psychosis|Dementia|Aggression|Agitation|Alzheimer Dementia
Interventions: DRUG: MP-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Vertistop® D and Vertistop® L in the Prevention of BPPV Recurrence
Status: COMPLETED
Conditions: Benign Paroxysmal Positional Vertigo|Vitamin D|Antioxidants
Interventions: DRUG: Vertistop® D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Trial of Behavioral Economic Approaches to Reduce Unnecessary Opioid Prescribing
Status: COMPLETED
Conditions: Acute Pain
Interventions: BEHAVIORAL: Individual audit feedback|BEHAVIORAL: Peer comparison feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A RCT Evaluating the Clinical Benefit of a Silver Dressing in the Treatment of Venous Leg Ulcers
Status: RECRUITING
Conditions: Wound Heal
Interventions: DEVICE: Biatain Ag|DEVICE: Cutimed Siltec Sorbact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the ScalpelCric Set and Comparison With Two Further Techniques of Cricothyrotomy
Status: COMPLETED
Conditions: Cricothyroidotomy
Interventions: DEVICE: Scalpel Bougie technique (plastic laryngeal model)|DEVICE: Seldinger technique (plastic laryngeal model)|DEVICE: Surgical technique (plastic laryngeal model)|DEVICE: Scalpel Bougie technique (porcine laryngeal model)|DEVICE: Surgical technique (porcine laryngeal model)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Carbamylated Erythropoietin (CEPO) to Treat Patients With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Lu AA24493 (CEPO)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Optimal Dose Selection of Intranasal Dexmedetomidine During Breast Lumpectomy Under Local Anaesthesia
Status: COMPLETED
Conditions: Intranasal Dexmedetomidine Breast Cancer Local Anaesthesia
Interventions: DRUG: 0.9% saline|DRUG: dexmedetomidine 1µg.kg-1|DRUG: dexmedetomidine 1.5µg.kg-1|DRUG: Dexmedetomidine 2µg.kg-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Platelet-rich Plasma Intradermal Injection Combined With 308 nm Excimer Light for Treating Stable Acral Vitiligo
Status: RECRUITING
Conditions: Vitiligo
Interventions: COMBINATION_PRODUCT: PRP+308nm|COMBINATION_PRODUCT: NS+308nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient
Status: COMPLETED
Conditions: Stroke|Healthy
Interventions: DEVICE: transcranial direct current stimulation (tDCS)|PROCEDURE: constraint induced movement therapy (CIMT)|DEVICE: transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Nutritional Supplements for Treatments of Dry Eye
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DIETARY_SUPPLEMENT: Hydroeye|OTHER: Inactive Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Sequential Immunization of Recombinant SARS-CoV-2 Fusion Protein Vaccine
Status: UNKNOWN
Conditions: COVID-19 Pandemic
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Fusion Protein Vaccine 10μg|BIOLOGICAL: Recombinant SARS-CoV-2 Fusion Protein Vaccine 25μg|BIOLOGICAL: SARS-Cov-2 Vaccine Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION