pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: IMPACT OF THE BIOLOGICAL RATIO ON MEDICAL DECISION MAKING IN WOMEN SUSPECTED OF PREECLAMPSIA
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DIAGNOSTIC_TEST: soluble fms-like tyrosine kinase (sFlt-1) / placental growth factor (PlGF) ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC
Status: UNKNOWN
Conditions: Asymptomatic Brain Metastases of Non Small Cell Lung Cancer
Interventions: DRUG: EGFR-TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intra-articular Versus Subacromial Steroid Injections on Clinical Outcomes in Adhesive Capsulitis
Status: WITHDRAWN
Conditions: Adhesive Capsulitis
Interventions: DRUG: Lidocaine + Kenalog|DRUG: Lidocaine + Kenalog|DRUG: Lidocaine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Standardized Time- and Score-oriented Treatment of Moderate and Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: DRUG: Pimecrolimus|DRUG: Tacrolimus|DRUG: Prednisolone|DRUG: Ciclosporin A|DRUG: Dermatop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND)
Status: COMPLETED
Conditions: Fetal Alcohol Syndrome|Alcohol-related Neurodevelopmental Disorder
Interventions: BEHAVIORAL: neurocognitive habilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Evaluation of a Peer Counseling Breastfeeding Support Program for Mother-preterm Infant Dyads
Status: COMPLETED
Conditions: Infant Premature
Interventions: BEHAVIORAL: breastfeeding mother-to-mother support|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LXI-15029 in Patients With Advanced Malignant Solid Tumors
Status: UNKNOWN
Conditions: Advanced Breast Cancer
Interventions: DRUG: LXI-15029|DRUG: LXI-15029+Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Strong Ion Difference Fluid vs Hartmann's Solution on Acid-Base Status in Sepsis
Status: COMPLETED
Conditions: Septicemic Shock
Interventions: COMBINATION_PRODUCT: High SID fluid|COMBINATION_PRODUCT: Hartmann's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DIETARY_SUPPLEMENT: Prebiotic Bar +CPT|BEHAVIORAL: Non-Prebiotic Bar +CPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Deep Breathing Excer. With & Without PMR on Post C Section LBP, QOS & PA
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: OTHER: Deep breathing excercises|OTHER: Deep breathing exercises +and progressive muscle relaxation techniques|OTHER: Deep breathing exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Effects of Integrating ECD Activities Into Bangladesh Government's Urban Lactating Mothers Allowance Program for the Poor on Children's Cognition and Behavior in Rangpur City Corporation, Bangladesh
Status: UNKNOWN
Conditions: Early Childhood Development
Interventions: OTHER: Lactating allowance and psycho social stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intraoperative Electromyographic Monitoring of the Recurrent Laryngeal Nerve in Thyroid Surgery
Status: UNKNOWN
Conditions: Thyroid Surgery|Recurrent Laryngeal Nerve|Electromyographic Monitoring
Interventions: DEVICE: Medtronic Xomed Nerve Integrity Monitor (NIM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Mindfulness Program on Perceived Wellness, Eating Habits and Relationship to Food
Status: UNKNOWN
Conditions: Diet, Healthy|Food Habits|Mental Fatigue|Mental Stress|Mental Health Issue|Nutrition Poor|Nutrition Disorders|Eating, Compulsive|Eating Behavior|Eating Disorder Weight Fixation|Eating Disorders|Nutrition, Healthy|Dietary Habits
Interventions: BEHAVIORAL: Nutrition and Mental health counseling|BEHAVIORAL: Nutrition and Mental health counseling with Nourish Carolina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of Repeat Administration of FX006 Administered to Patients With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: FX006 32 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Fallopian Tube Clear Cell Adenocarcinoma|Fallopian Tube Endometrioid Adenocarcinoma|Fallopian Tube Mucinous Adenocarcinoma|Fallopian Tube Serous Adenocarcinoma|Fallopian Tube Transitional Cell Carcinoma|Fallopian Tube Undifferentiated Carcinoma|FIGO Stage III Ovarian Cancer|FIGO Stage IIIA Ovarian Cancer|FIGO Stage IIIA1 Ovarian Cancer|FIGO Stage IIIA1(i) Ovarian Cancer|FIGO Stage IIIA1(ii) Ovarian Cancer|FIGO Stage IIIA2 Ovarian Cancer|FIGO Stage IIIB Ovarian Cancer|FIGO Stage IIIC Ovarian Cancer|FIGO Stage IVA Ovarian Cancer|FIGO Stage IVB Ovarian Cancer|Malignant Ovarian Brenner Tumor|Ovarian Clear Cell Adenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Adenocarcinoma|Ovarian Seromucinous Carcinoma|Ovarian Serous Adenocarcinoma|Ovarian Transitional Cell Carcinoma|Ovarian Undifferentiated Carcinoma|Primary Peritoneal Carcinoma|Primary Peritoneal Serous Adenocarcinoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Biphasic Insulin Aspart 30 on Blood Glucose Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose of GAP-134 as a 24-hour IV Infusion in Healthy Japanese Males
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: GAP-134
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infections|HIV Infections
Interventions: BIOLOGICAL: tgAAC09|BIOLOGICAL: tgAAC09|BIOLOGICAL: tgAAC09|OTHER: Formulation buffer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: WEE1 Inhibitor MK-1775, Docetaxel, and Cisplatin Before Surgery in Treating Patients With Borderline Resectable Stage III-IVB Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery|DRUG: WEE1 Inhibitor AZD1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Multicenter Study to Evaluate the Acid-inhibitory and Dose-response Efficacy of TAK-438 (20 mg, 40 mg) in Patients With Proton Pump Inhibitor (PPI) - Resistant Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: TAK-438|DRUG: TAK-438
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Assessment of Risk Factors for Appropriate ICD (Implantable Cardioverter-defibrillator) Intervention in Patients With Ischemic Cardiomyopathy
Status: COMPLETED
Conditions: ICD|Cardiomyopathy Ischemic|Primary Prevention
Interventions: DEVICE: ICD implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Visual Screening in Ontario
Status: COMPLETED
Conditions: Amblyopia
Interventions: OTHER: Crowded HOTV Acuity Test|OTHER: Preschool Randot Stereoacuity Test|DEVICE: Plusoptix Autorefractor|OTHER: Comprehensive Eye Exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sintilimab Plus Chemotherapy Followed by dCRT in Locally Advanced ESCC
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Sintilimab plus Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHR1701 Alone or in Combination With SHR2554 in Relapsed or Refractory Classical Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed or Refractory Hodgkin Lymphoma
Interventions: DRUG: SHR2554+ SHR1701|DRUG: SHR-1701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts
Status: RECRUITING
Conditions: Tuberculosis|Latent Tuberculosis
Interventions: DRUG: Rifampin and Isoniazid|DRUG: isoniazid and rifapentine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Financial Incentives to Increase Live Kidney Donor Follow-up Compliance
Status: ACTIVE_NOT_RECRUITING
Conditions: Living Donors|Nephrectomy|Kidney
Interventions: OTHER: Financial Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: Subetta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Inhaled Versus Intravenous Milrinone for Patients Undergoing Mitral Valve Replacement Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Valve Replacement|Pulmonary Hypertension|Inhaled Milrinone|Intravenous Milrinone
Interventions: DRUG: Inhaled Milrinone|DRUG: IV Milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: RHYTHM-I: Investigating Hypoxia in Rectal Tumours
Status: COMPLETED
Conditions: Hypoxia in Rectal Cancer
Interventions: OTHER: Pimonidazole|OTHER: F-MISO PET|OTHER: pCT|OTHER: Functional MRI|PROCEDURE: Biopsy|PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epidural Analgesia Versus IV Analgesia in Lumbar Spine Fusions
Status: TERMINATED
Conditions: Lumbar Spine Fusion|Pain|Back Pain
Interventions: OTHER: Epidural Catheter - Dilaudid|DRUG: Dilaudid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of the Effectiveness of Nursing Care Education Provided With Immersive Virtual Reality
Status: RECRUITING
Conditions: Virtual Reality|Nursing Care|Colorectal Surgery|Nursing Student|Education
Interventions: OTHER: simulation group|OTHER: immersive virtual reality|OTHER: observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Porfiromycin Used as an Adjuvant to Radiation Therapy in Postoperative Head and Neck Cancer Patients
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Porfiromycin|DRUG: Placebo|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sandostatin LAR® Depot in Patients With Primary Insulin Hypersecretion (PIH) and at Least Moderate Obesity
Status: COMPLETED
Conditions: Primary Insulin Hypersecretion|Obesity
Interventions: DRUG: Sandostatin LAR Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A to Treat Arm Tremor
Status: COMPLETED
Conditions: Essential Tremor of the Upper Limbs
Interventions: DRUG: IncobotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Contribution of Monophosphoryl Lipid A (MPL) to a Grass Pollen Allergy Vaccine
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Grass MATA MPL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography and Microperimetry Biomarker Evaluation in Patients With Geographic Atrophy Study
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Geographic Atrophy|Visual Field Defect, Central Scotoma of Both Eyes
Interventions: DIAGNOSTIC_TEST: Natural history study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL)
Status: TERMINATED
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma|Lymphoma, Non-Hodgkin
Interventions: DRUG: JCAR017|DRUG: Lymphodepleting|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Attitudes Towards Organ Donation in the United States on MTurk
Status: COMPLETED
Conditions: Individual Difference
Interventions: BEHAVIORAL: Online Individualistic Prime (statement writing)|BEHAVIORAL: Online Collectivistic Prime (statement writing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neural, Behavioural, and Clinical Effects of tDCS in PDOC; Feasibility Study
Status: UNKNOWN
Conditions: Consciousness Disorder|Brain Injuries|Vegetative State|Minimally Conscious State
Interventions: OTHER: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)
Status: RECRUITING
Conditions: Cholangiocarcinoma|Multiple Myeloma|Colon Cancer|Rectal Cancer
Interventions: OTHER: Return of Genetic Results: Biomarker information from cancer cells|OTHER: Return of Genetic Results: Inherited mutations related to cancer|OTHER: Return of Genetic Results: Inherited mutations related to other medical issues
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Abdominal Plane Blocks in Postoperative Pain Control in Patients Undergoing LSG
Status: COMPLETED
Conditions: Bariatric Surgical Procedures|Anesthesia and Analgesia|Anesthesia, Regional
Interventions: PROCEDURE: TAP block group|PROCEDURE: m-TAPA block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Different Hydrocortisone Replacement Doses on the Partitioning and Flexibility of Ectopic Lipids in Patients With Corticotropic Hypopituitarism
Status: TERMINATED
Conditions: Hypopituitarism|Hydrocortisone|Lipids|Fatty Acids, Nonesterified|Insulin Sensitivity
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Post-market Evaluation of an Echogenic Catheter
Status: UNKNOWN
Conditions: Peripheral Nerve Block Procedure
Interventions: DEVICE: EchoGlo Nerve Block Catheter|DEVICE: Pajunk® Nerve Block Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CAD-9303 in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: CAD-9303|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Chronic Exposure of the Population Living on the Atlantic Coast and on the Caribbean Coast, in Martinique, During the Stranding Period and Outside the Stranding Period of Sargassum Seaweeds
Status: COMPLETED
Conditions: Obstructive Ventilatory Disorders
Interventions: PROCEDURE: FeNO (fractional exhaled nitric oxide)|PROCEDURE: Spirometry|OTHER: Physical examination|OTHER: Interrogation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Paclitaxel in Treating Patients With Recurrent or Persistent Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: SEL|DRUG: FIR|DRUG: CILO|DRUG: Placebo to match FIR|DRUG: Placebo to match CILO|DRUG: Placebo to match SEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of ORMD-0801 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: ORMD-0801|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Combination Chemotherapy, and Radiation Therapy Before Surgery in Treating Adult Patients With Locally Advanced Gastroesophageal Junction or Gastric Cardia Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Gastric Cardia Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Stage IB Gastric Cancer AJCC v7|Stage II Gastric Cancer AJCC v7|Stage IIA Gastric Cancer AJCC v7|Stage IIB Gastric Cancer AJCC v7|Stage IIIA Gastric Cancer AJCC v7|Stage IIIB Gastric Cancer AJCC v7
Interventions: DRUG: Carboplatin|PROCEDURE: Computed Tomography|DRUG: Fluorouracil|OTHER: Laboratory Biomarker Analysis|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Pancreatic Cancer Screening
Status: RECRUITING
Conditions: Pancreatic Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Cholangiopancreatography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Endoscopic ultrasound|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Piloting the Feasibility of FLT-PET/CT Non-Small Cell Lung Cancer Managed With SBRT
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer (NSCLC)
Interventions: PROCEDURE: FLT-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Hemay005 in Patients With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Active Ankylosing Spondylitis
Interventions: DRUG: Hemay005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of DRM02 in Subjects With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: DRM02|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone and Its Metabolites in GID
Status: COMPLETED
Conditions: Transsexualism
Interventions: DRUG: testosterone undecanoate alone|DRUG: testosterone undecanoate plus letrozole|DRUG: testosterone undecanoate plus dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Preliminary Efficacy of Unilateral Latanoprost-loaded Punctual Plug -EXP-LP
Status: UNKNOWN
Conditions: Glaucoma|Ocular Hypertension|IOP
Interventions: DEVICE: drug delivery system|DRUG: XALATAN®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) and Its Metabolites in Blood
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Hydroxyprogesterone caproate 250 mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Dermatofibrosarcoma Protuberans in Patients 10 Years and Younger
Status: COMPLETED
Conditions: Dermatofibrosarcoma Protuberans
Interventions: PROCEDURE: MOHS micrographic surgery|PROCEDURE: Wide local excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractionated Stem Cell Infusions in Myeloma Patients Undergoing Autologous Stem Cell Transplant
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Fractionated Stem Cell Infusions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Stage II
Interventions: DRUG: Ribociclib (neoadjuvant)|DRUG: Chemotherapy (adjuvant)|DRUG: Ribociclib (adjuvant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compared to MRI
Status: COMPLETED
Conditions: Development of Standardized Assessment TAVI and MitraClip Procedures by Echocardiography|Aortic Stenosis|Mitral Valve Insufficiency
Interventions: DEVICE: Echography GE Healthcare Vivid E9
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity and Safety of GlaxoSmithKline Biologicals' Infanrix™-IPV+Hib Vaccine
Status: COMPLETED
Conditions: Poliomyelitis|Tetanus|Acellular Pertussis|Diphtheria|Haemophilus Influenzae Type b
Interventions: BIOLOGICAL: Infanrix™-IPV+Hib|BIOLOGICAL: Infanrix™ IPV|BIOLOGICAL: Hiberix™|BIOLOGICAL: Synflorix™|BIOLOGICAL: Rotarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Mircera in Hemoglobin Control of Patients Transitioning to Dialysis.
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta|DRUG: epoetin alfa|DRUG: darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study on Dual And Triple Therapies Based on Peginterferon Alfa (e.g. Pegasys) in Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peg-IFN Alfa-2a|DRUG: Peg-IFN Alfa-2b|DRUG: Ribavirin|DRUG: Boceprevir|DRUG: Telaprevir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Study To Evaluate The Efficacy And Safety Of An Investigational Drug In Adolescent And Adult Subjects With Asthma Uncontrolled on Moderate-Dose ICS Therapy.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GW685698X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Resistant Starch Bagels on Risk Factors of Type 2 Diabetes and Colorectal Cancer
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Resistant Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetic Properties of 200 and 400 mg Acyclovir Tablet in Indonesia Healthy Subject
Status: COMPLETED
Conditions: Drug Use
Interventions: DRUG: Acyclovir 200 MG|DRUG: Acyclovir 400 MG|DRUG: Zovirax 200 MG Tablet|DRUG: Zovirax 400 MG Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib and Green Tea Extract (Polyphenon® E) in Preventing Cancer Recurrence in Former Smokers Who Have Undergone Surgery for Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: Polyphenon E|DRUG: erlotinib hydrochloride|OTHER: Erlotinib placebo|OTHER: Polyphenon E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of an Adapted Sports Program Based on Fencing to Reduce Physical Deconditioning in Adult Hematology Patients
Status: RECRUITING
Conditions: Leukemia|Lymphoma
Interventions: OTHER: Adapted sport program based on fencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing the Impact of Contraceptives on Bone Health Using 41Ca
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Disorders of Bone Development and Growth
Interventions: DRUG: Combined Oral Contraceptive (COC)|DRUG: Contraceptive Vaginal Ring (CVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging
Status: TERMINATED
Conditions: Coronary Atherosclerosis|Coronary Artery Disease|Contrast-induced Nephropathy|Cerebrovascular Disease|Alzheimer Disease|Chronic Coronary Insufficiency|Stable Chronic Angina
Interventions: RADIATION: Coronary computed tomography angiography|RADIATION: Quantitative coronary angiography, intravascular imaging with percutaneous intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Adult Diffuse Large B-Cell Lymphoma|B-Cell Non-Hodgkin Lymphoma|Follicular Lymphoma|Mantle Cell Lymphoma|Non-Hodgkin Lymphoma|T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Bortezomib|DRUG: Carmustine|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Melphalan|DRUG: Rituximab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha-1 Blockade for Alcohol Use Disorder (AUD)
Status: RECRUITING
Conditions: Alcohol Use Disorder (AUD)
Interventions: DRUG: Doxazosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic Total Occlusions
Status: RECRUITING
Conditions: Multi Vessel Coronary Artery Disease|Non-ST Elevation Myocardial Infarction|Unstable Angina|Stable Angina|Coronary Artery Disease|Percutaneous Coronary Intervention|Optical Coherence Tomography
Interventions: DEVICE: PCI with OCT guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Corticoids For Empyema And Pleural Effusion In Children
Status: COMPLETED
Conditions: Parapneumonic Pleural Effusion|Empyema
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Different Feeding Modes on Patients With Intracerebral Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: BEHAVIORAL: Basic treatment|DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: GSK1292263|DRUG: GSK1292263 matching placebo|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Influence of Proteins on the Bioavailability of Carotenoids
Status: COMPLETED
Conditions: Absorption; Chemicals|Healthy Diet|Metabolism
Interventions: OTHER: Intervention with soy protein isolate|OTHER: Intervention with whey protein|OTHER: Intervention without protein addition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies
Status: RECRUITING
Conditions: Advanced Cancer|Ovarian Cancer|Lung Cancer|Colon Cancer|Plasma Cell Neoplasm|Multiple Myeloma|HNSCC|Microsatellite Stable Colorectal Carcinoma|MSS-CRC
Interventions: DRUG: Dose escalation: COM902 monotherapy.|COMBINATION_PRODUCT: Evaluation of safety/tolerability: COM902 in combination with COM701 (both at the RDFE)|DRUG: Cohort expansion: COM902 (RDFE) monotherapy.|DRUG: Cohort expansion: COM902 in combination with COM701 (both at the RDFE).|COMBINATION_PRODUCT: Cohort expansion: Triplet combination of COM902 + COM701 + Pembrolizumab.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: PF-04449913
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety|Post-traumatic Stress Disorder|Stress|Worries; Pain or Disability|Breath Shortness
Interventions: BEHAVIORAL: Blueprint|BEHAVIORAL: Education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Three Different Formulations of Prednisolone Acetate 1%
Status: COMPLETED
Conditions: Glaucoma|Cataract
Interventions: DRUG: Pred Forte|DRUG: EconoPred Plus|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull
Status: COMPLETED
Conditions: Athletes
Interventions: OTHER: Performance-Enhancing Substances|OTHER: Placebo|OTHER: Baseline (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Objective Verification of Physiologic Changes During Accommodation Under Binocular, Monocular, and Pinhole Conditions
Status: COMPLETED
Conditions: Accommodation
Interventions: DEVICE: the WAM-5500 binocular autorefractor/keratometer (Grand Seiko Co. Ltd., Hiroshima, Japan)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Image Guided Surgery for Margin Assessment of Head and Neck Cancer Using Cetuximab-IRDye800CW cONjugate
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma|Margin Assessment
Interventions: DRUG: Cetuximab-IRDye800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acupuncture in Chemotherapy-induced Peripheral Neuropathy in Women With Breast Cancer
Status: RECRUITING
Conditions: Peripheral Neuropathy
Interventions: PROCEDURE: Acupuncture|DRUG: treatment of physician choice, according to the standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Manipulation and Neuromuscular Performance on Amateur Cyclists
Status: WITHDRAWN
Conditions: Manual Therapies
Interventions: PROCEDURE: Spinal manipulative therapy|OTHER: Sham spinal manipulative therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Icodextrin on the Treatment Outcome of Peritoneal Dialysis Patients During Acute Peritonitis
Status: COMPLETED
Conditions: Peritonitis
Interventions: DRUG: Icodextrin|DRUG: glucose-based peritoneal dialysate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Prevention of Methicillin Resistant Staphylococcus Aureus (MRSA) Transmission in the Community
Status: COMPLETED
Conditions: MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Interventions: DRUG: Unsupervised Decolonization|DRUG: Supervised Decolonization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.
Status: COMPLETED
Conditions: Central Nervous System Sensitization|Pain|Hyperalgesia
Interventions: DRUG: Target-controlled naloxone-infusion|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: aleglitazar+metformin|DRUG: placebo+metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Decision Support Among Surrogate Decision Makers of the Chronically Critically Ill (INVOLVE)
Status: COMPLETED
Conditions: Critical Illness
Interventions: BEHAVIORAL: INVOLVE|BEHAVIORAL: Informational Support|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interscalene Block With and Without Liposomal Bupivacaine in Shoulder Surgery
Status: COMPLETED
Conditions: Rotator Cuff Tear|Postoperative Pain
Interventions: DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy and Safety of Intravenous Sulbactam-ETX2514 in the Treatment of Patients With Infections Caused by Acinetobacter Baumannii-calcoaceticus Complex
Status: COMPLETED
Conditions: Acinetobacter Baumannii-calcoaceticus Complex|Hospital-acquired Bacterial Pneumonia|Ventilator-associated Bacterial Pneumonia|Bacteremia|Colistin Resistant ABC
Interventions: DRUG: Sulbactam|DRUG: Durlobactam|DRUG: Colistin|DRUG: Imipenem/Cilastatin 500 mg/500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oropharyngeal Administration of Mother's Milk in Preterm Infants and Neonatal Infection
Status: COMPLETED
Conditions: Preterm Infant|Neonatal SEPSIS|Neonatal Feeding Disorder
Interventions: PROCEDURE: Oropharyngeal Administration of Mother's Milk (OPAMM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Retrospective Study of C-kit Mutation Status in Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib.
Status: UNKNOWN
Conditions: Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib
Interventions: PROCEDURE: Tumor biopsies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapeutic Hepatitis B Vaccine (Mimogen-based) Joint Entecavir in Treating Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: Therapeutic HBV vaccine|DRUG: entecavir|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BMS-247550 in Treating Patients With Liver or Gallbladder Cancer
Status: TERMINATED
Conditions: Adult Primary Cholangiocellular Carcinoma|Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Localized Extrahepatic Bile Duct Cancer|Localized Gallbladder Cancer|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: ixabepilone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Intravenous Iron Therapy in Patients With Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Anemia|Surgery|Iron Deficiency Anemia|Surgery--Complications
Interventions: DRUG: Ferric carboxymaltose|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Dimebon tablet for oral administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to Influenza Virus Vaccination in Patients Immunocompromised Due to Chemotherapy
Status: COMPLETED
Conditions: Mamma Carcinoma|Heart Failure
Interventions: BIOLOGICAL: influenza virus vaccine (influvac or vaxigrip)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Diagnosis of Coronary Artery Stenoses by Doppler Echocardiography
Status: COMPLETED
Conditions: Stable Angina Pectoris|Unstable Angina Pectoris|Acute Myocardial Infarction
Interventions: PROCEDURE: Doppler echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Incidence of Jarisch-Herxheimer Reaction in Leptospirosis Patients in New Caledonia
Status: UNKNOWN
Conditions: Leptospirosis|Jarisch Herxheimer Reaction
Interventions: OTHER: Blood collection|OTHER: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Coronary Rotational Atherectomy Elective vs. Bailout in Severely Calcified Lesions and Chronic Renal Failure
Status: UNKNOWN
Conditions: Coronary Artery Disease|Chronic Renal Failure
Interventions: DEVICE: Percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-immunogenic Recombinant Staphylokinase vs Placebo in Patients With Intermediate High-risk Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism
Interventions: DRUG: Non-immunogenic recombinant staphylokinase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Outcomes of SILS+1 Versus CLS for Distal Gastric Cancer
Status: UNKNOWN
Conditions: Surgery
Interventions: PROCEDURE: single-incision plus one-port laparoscopic surgery|PROCEDURE: conventional laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block and Effect of 10 Versus 30 ml Ropivacaine on Muscle Strength: a Randomized Study in Healthy Volunteers
Status: COMPLETED
Conditions: Muscle Strength|Healthy Volunteers
Interventions: PROCEDURE: Adductor canal block with ropivacaine 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Prebiotics on Cognitive Functioning and Weight Gain in Psychosis
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DIETARY_SUPPLEMENT: prebiotics|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of the Combination of L-Arabinose and Indigestible Dextrin on Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Oolong tea containing L-arabinose and indigestible dextrin|DIETARY_SUPPLEMENT: Oolong tea (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Add-on to Micamlo BP Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan + amlodipine|DRUG: hydrochlorothiazide|DRUG: Telmisartan + amlodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Pirtobrutinib (LOXO-305) on Repaglinide (CYP2C8 Substrate) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Repaglinide|DRUG: Pirtobrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Depressed Mood Improvement Through Nicotine Dosing-3 (Depressed MIND3) Extension
Status: RECRUITING
Conditions: Depressive Disorder
Interventions: DRUG: Transdermal Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE