pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Preliminary Validation of an in Vitro Diagnosis-medical Device for Hepatitis B Screening
Status: COMPLETED
Conditions: Hepatitis B|Healthy|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Demonstrator MAGIA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Adult Glioblastoma|Adult Gliosarcoma
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Cediranib Maleate|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety for Cimicifuga/Hypericum Product
Status: UNKNOWN
Conditions: Perimenopausal Disorder
Interventions: DRUG: Cimicifuga + Hiperico|DRUG: Cimicifuga Herbarium|DRUG: Aplause®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coping With Chronic Fatigue Syndrome: Development of a Community-based Patient Education Program
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Coping|Patient Education
Interventions: BEHAVIORAL: Patient education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Success Rate Between Distal Radial Approach and Radial Approach in STEMI
Status: COMPLETED
Conditions: Distal Radial Artery Approach|ST Elevation Myocardial Infarction
Interventions: PROCEDURE: Distal radial artery|PROCEDURE: Radial artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin|DRUG: Placebo|DRUG: Metformin|DRUG: Sulphonylruea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Computerized Cognitive Stimulation Intervention Adapted to the Level of Cognitive Reserve
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Cognitive Dysfunction
Interventions: BEHAVIORAL: Computerized cognitive stimulation program|BEHAVIORAL: Face-to-face training-explanatory session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits
Status: UNKNOWN
Conditions: Constipation
Interventions: DIETARY_SUPPLEMENT: Prebiotic fructans|DIETARY_SUPPLEMENT: Non-prebiotic maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GMK-UNI Anatomical UKA: Fixation of Cemented vs Cementless Designs
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Unicompartmental Knee Arthroplasty (UKA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Risk of Acute Kidney Injury in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: serum cystatin C|DIAGNOSTIC_TEST: serum beta-microglubulin|DIAGNOSTIC_TEST: urine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Vitamin D Supplementation on Muscle Power in Elite Cyclist
Status: COMPLETED
Conditions: Muscle Power
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topotecan and Radiation Therapy in Treating Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Esophageal Cancer|Lung Cancer|Lymphoma
Interventions: DRUG: topotecan hydrochloride|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prebiotic in Preventing Low Birth Weight
Status: COMPLETED
Conditions: Birth Weight <2500gm|Genitourinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: Fructooligosaccharide|DIETARY_SUPPLEMENT: Pocari-Sweat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Furosemide Plus Small HSS in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)
Status: COMPLETED
Conditions: Heart Failure，Congestive
Interventions: DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety, Tolerability and Efficacy of Idebenone in Duchenne Muscular Dystrophy (DELPHI Extension)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Idebenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Acute Dystonia or Parkinsonism
Status: COMPLETED
Conditions: Schizophrenia|Extrapyramidal Syndrome
Interventions: DRUG: Risperidone and Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Matched Targeted Therapy For High-Risk Leukemias and Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent, Refractory, or High Risk Leukemias|Matched Targeted Therapy
Interventions: GENETIC: Leukemia Profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lipoabdominoplasty With Anatomic Definition Versus Traditional Abdominoplasty
Status: UNKNOWN
Conditions: Abdomen Enlarged
Interventions: PROCEDURE: modified saldhana's technique|PROCEDURE: Traditional abdominoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PEP005 Gel - Evaluation of Local Tolerability After Exposure to Ingenol Mebutate Gel Followed by Hand Washing in Healthy Subjects
Status: COMPLETED
Conditions: Healthy|Actinic Keratosis
Interventions: DRUG: PEP005 Gel|DRUG: PEP005 Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of QGE031 Compared With Placebo in Patients Aged 18-75 Years With Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: QGE031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Our Whole Lives Gemini: Virtual Integrative Medical Group Visits for Managing Chronic Pain
Status: RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Our Whole Lives (OWL)|BEHAVIORAL: Low Dose Mindfulness Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D and Its Metabolites Quantification in Adipose Tissues of Obese and Non-obese Patients.
Status: RECRUITING
Conditions: Obesity; Endocrine
Interventions: BIOLOGICAL: subcutaneous and visceral adipose tissue biopsies|BIOLOGICAL: blood samples analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of Oxytocin and Interoception in Functional Neurological Disorder
Status: RECRUITING
Conditions: Functional Neurological Disorder
Interventions: DEVICE: Respiration resistance sensitivity task (RRST)|BEHAVIORAL: Heartbeat Tracking (HBT)|DEVICE: Heartbeat evoked potential (HEP)|DEVICE: Libet task
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study for Subjects With Relapsed/Refractory Non- Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non Hodgkin's Lymphoma Refractory/Relapsed
Interventions: DRUG: N803|BIOLOGICAL: CD19t-haNK suspension|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Sciatica|Lumbosacral Radiculopathy
Interventions: DRUG: MDT-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Mobile Cognitive Behavioral Therapy Application
Status: RECRUITING
Conditions: Anxiety Disorders and Symptoms|Depression|Bipolar Disorder|Symptoms
Interventions: BEHAVIORAL: Personalized MAYA Mobile App|BEHAVIORAL: General MAYA Mobile App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Profile of M108 Monoclonal Antibody in Patients With Advanced Unresectable Solid Tumors in China
Status: RECRUITING
Conditions: Advanced Unresectable Solid Tumors
Interventions: DRUG: M108|DRUG: M108
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transapical Beating-heart Myectomy for the Treatment of Apical Hypertrophic Cardiomyopathy
Status: RECRUITING
Conditions: Apical Hypertrophic Cardiomyopathy
Interventions: DEVICE: Transapical beating-heart septal myectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Seneca Valley Virus in Patients With Solid Tumors With Neuroendocrine Features
Status: UNKNOWN
Conditions: Carcinoid|Neuroendocrine
Interventions: DRUG: Seneca Valley Virus (biological agent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy and Safety of Gelaspan
Status: COMPLETED
Conditions: Hypovolemia
Interventions: DRUG: Gelaspan 4%|DRUG: Gelofusine 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Assess if CC-930 is Safe in Treating Subjects With Discoid Lupus Erythematosus
Status: TERMINATED
Conditions: Discoid Lupus
Interventions: DRUG: CC-930|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anti-inflammatory Effects of Seroflo and Seretide in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Sereflo|DRUG: Seretide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Evaluate TREXIMET in Adolescents With Migraine and Healthy Subjects Administered at Three Doses.
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: This is a pharmacokinetic study (Treximet)|DRUG: This is a pharmacokinetic study (Treximet)|DRUG: This is a pharmacokinetic study (Treximet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Survey to Collect Treatment Experience Feedback From Patients, Physicians, Nurses and Carers After Switching to Paliperidone Palmitate 3-monthly
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone Palmitate 3-Month Formulation (PP3M)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Immune Response of a HIV Candidate Vaccine After Administration of One Chloroquine Dose
Status: COMPLETED
Conditions: AIDS
Interventions: BIOLOGICAL: GSK Biologicals' HIV vaccine (732461)|DRUG: Chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Twins Nutrition Study (TwiNS): Vegan vs. Omnivore
Status: COMPLETED
Conditions: Lipid Metabolism|Glucose Intolerance|Weight Change, Body|Microbiome|Inflammation|Immune Function
Interventions: BEHAVIORAL: Vegan diet|BEHAVIORAL: Omnivore diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Treatment of Substance Abuse and Child Maltreatment
Status: COMPLETED
Conditions: Substance Use|Child Maltreatment
Interventions: BEHAVIORAL: Reinforcement for drug & alcohol abstinence|BEHAVIORAL: Parenting intervention|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572)
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PENG Versus Femoral Nerve Block in Neck of Femur Fracture
Status: UNKNOWN
Conditions: Neck of Femur Fracture
Interventions: DRUG: Lidocain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nudges and Incentives to Enhance the Opioid Treatment Workforce
Status: COMPLETED
Conditions: Opioid Abuse (Disorder)
Interventions: BEHAVIORAL: Phase 1 Condition 1|BEHAVIORAL: Phase 1 Condition 2|BEHAVIORAL: Phase 1 Condition 3|BEHAVIORAL: Phase 1 Condition 4|BEHAVIORAL: Phase 2 Condition 1|BEHAVIORAL: Phase 2 Condition 2|BEHAVIORAL: Phase 2 Condition 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Hemodynamic Effects and Pharmacokinetics of CXL-1020 in Patients With Stable Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CXL-1020|DRUG: CXL-1020|DRUG: Placebo for CXL-1020 Cohort 1|DRUG: Placebo for CXL-1020 Cohort 2|DRUG: CXL-1020 Dose for Echo Cohort A|DRUG: CXL-1020 Doses for Echo Cohort B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GemOx and Vandetanib in Advanced Solid Malignancy
Status: COMPLETED
Conditions: Advanced Incurable Solid Malignancy
Interventions: DRUG: Vandetanib|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Evaluation of the Pregnant Moms' Empowerment Program
Status: COMPLETED
Conditions: Violence|Depression|Posttraumatic Stress Disorder|Parenting|Infant Development|Child Behavior
Interventions: BEHAVIORAL: Pregnant Moms' Empowerment Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sleep Duration Required to Restore Performance During Chronic Sleep Restriction
Status: COMPLETED
Conditions: Sleep|Sleep Deprivation|Insufficient Sleep Syndrome
Interventions: BEHAVIORAL: Sleep:wake 1|BEHAVIORAL: Sleep:wake 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DRUG: Niacin\Laropiprant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery
Status: COMPLETED
Conditions: Pain, Acute|Opioid Misuse|Obstetric Pain|Cesarean Section Complications
Interventions: OTHER: Deterra activated charcoal pouch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Merz Cheek Fullness Assessment Scale in the Treatment of Midface Volume Deficit
Status: COMPLETED
Conditions: Moderate to Severe Midface Volume Deficit
Interventions: DEVICE: Belotero® Volume Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: PROCEDURE: Laser interstitial thermal therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cannabidiol (CBD) Versus Placebo as an Adjunct to Treatment in Early Psychosis
Status: RECRUITING
Conditions: Early Psychosis
Interventions: DRUG: Cannabidiol oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Pharmacotherapy for Dual Dependence
Status: UNKNOWN
Conditions: Alcohol Dependence|Cocaine Dependence
Interventions: DRUG: Topiramate + Cognitive Behavioral Therapy|DRUG: Placebo + Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Comparison of Two Methods of Securing Endotracheal Tubes in Intensive Care : Elastic Adhesive Strips vs Lace In A Protective Sheath."
Status: COMPLETED
Conditions: Intubation Complication
Interventions: DEVICE: Elastic Adhesive Strips|DEVICE: Lace in A Protective Sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Radionuclide Therapy for Metastatic Melanoma [131I] ICF01012
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: [131I]ICF01012 (therapeutic dose level 1)|DRUG: [131I]ICF01012 (therapeutic dose level 2)|DRUG: [131I]ICF01012 (therapeutic dose level 3)|DRUG: [131I]ICF01012 (therapeutic dose level 4)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Picosecond and Q-switched Laser for Benign Pigmented Lesions Treatment
Status: UNKNOWN
Conditions: Benign Pigmented Lesions
Interventions: DEVICE: Picosecond laser|DEVICE: Q-switched Nd:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How NNC0174-0833 Behaves in Japanese and Caucasian Volunteers Who Are Normal Weight, Overweight or With Obesity
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: NNC0174-0833|DRUG: Placebo (NNC0174-0833)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of CAR-T in the Treatment of Relapsed and Refractory Hematopoietic and Lymphoid Tissue Tumors in Children
Status: RECRUITING
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Auto CAR-T|DRUG: Cyclophosphamide,Fludarabine|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DRUG: Maltodextrin|DRUG: Synbiotic|DRUG: Sevelamer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial of ADR-001 for IgA Nephropathy
Status: COMPLETED
Conditions: Glomerulonephritis , IGA
Interventions: BIOLOGICAL: infusion of ADR-001 (Mesenchymal stem cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The NOrwegian Tennis Elbow (NOTE) Study
Status: COMPLETED
Conditions: Lateral Epicondylitis|Tennis Elbow|Tendinopathy, Elbow
Interventions: OTHER: Heavy Slow Exercises|DEVICE: Extracorporeal Shock wave therapy|OTHER: Information and advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aggrastat Truncated Length Against Standard Therapies in Percutaneous Coronary Intervention
Status: WITHDRAWN
Conditions: Myocardial Infarction|Acute Coronary Syndromes|Unstable Angina|Percutaneous Coronary Intervention
Interventions: DRUG: Tirofiban (Aggrastat)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, and Immunogenicity Study of GLS-6150 in Healthy Volunteers and in Persons Previously Treated for Hepatitis C Virus Infection
Status: COMPLETED
Conditions: HCV Infection
Interventions: BIOLOGICAL: GLS-6150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the Elderly
Status: NOT_YET_RECRUITING
Conditions: Oropharynx Cancer|Frailty
Interventions: RADIATION: Modified dose and fields intensity modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bilateral Erector Spina Plane Block on Postoperative Analgesia in Cesarean Section Under SpinalAnaesthesia
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: OTHER: Spinal anesthesia + bilateral erector spine plane block|OTHER: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Face Masks to Reduce SARS-CoV-2 Infections (COVID-19) in Bangladesh
Status: WITHDRAWN
Conditions: Covid19
Interventions: DEVICE: Face mask|BEHAVIORAL: Face mask awareness|BEHAVIORAL: Face mask promotion through community values or individual information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Baby CHAMP Study (Children With Hemiparesis Arm and Movement Project)
Status: COMPLETED
Conditions: Hemiparesis|Cerebral Palsy
Interventions: BEHAVIORAL: Neurorehabilitation therapy with cast|BEHAVIORAL: Neurorehabilitation therapy with splint|BEHAVIORAL: Neurorehabilitation bimanual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Sunitinib Versus Placebo in Combination With Lanreotide in Patients With Progressive Advanced/Metastatic Midgut Carcinoid Tumors
Status: UNKNOWN
Conditions: Carcinoid Tumors
Interventions: DRUG: Lanreotide|DRUG: Placebo (for sunitinib)|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthesia on Postoperative Pain in Vaginal Hysterectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Marcaine 0.5 % Injectable Solution|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Early-Stage Breast Carcinoma|Invasive Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: DRUG: Anastrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angioplasty-stenting vs Optimal Medical Treatment on Post-thrombotic Syndrome Reduction
Status: RECRUITING
Conditions: Post Thrombotic Syndrome
Interventions: PROCEDURE: 60 patients benefit from immediate venous angioplasty stenting plus medical treatment, i.e. elastic compression and anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Plerixafor for Rescue of Poor Mobilizers in Autologous Stem Cell Transplant
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkins Lymphoma|Hodgkins Disease
Interventions: DRUG: G-CSF plus Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoapplication Versus Anti-VEGF Before Diabetic Vitrectomy
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy|Vitreous Hemorrhage|Tractional Retinal Detachment
Interventions: DRUG: Bevacizumab Injection [Avastin]|PROCEDURE: Peripheral Retinal Cryoapplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of EN001 in Patients With Duchenne Muscular Dystrophy
Status: NOT_YET_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: EN001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microbial and Periodontal Changes Associated With Conventional Versus Self Ligating Brackets
Status: UNKNOWN
Conditions: Pocket Depth|Plaque Accumulation|Gigival Bleeding
Interventions: DEVICE: conventional stainless steel orthodontic brackets ligated with stainless steel ligature (Oromco - USA)|DEVICE: passive self-ligating stainless steel orthodontic brackets (Oromco - USA)|DEVICE: active self-ligating stainless steel orthodontic brackets (Oromco - USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II AMA-1 Malaria Vaccine FMP2.1/AS02A Trial in Mali
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: FMP2.1/AS02A|BIOLOGICAL: Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: REmote COnditioning in Out-of-Hospital Cardiac Arrest
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: No remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Medical Device Software "Lipidica 1.0" for Processing Data Generated by Lipidomic Analysis in Pancreatic Cancer Screening
Status: NOT_YET_RECRUITING
Conditions: Pancreas Cancer|Pancreatic Ductal Adenocarcinoma|Hereditary Diseases|Pancreatitis, Chronic
Interventions: DEVICE: software Lipidica|PROCEDURE: endoscopic ultrasonography|PROCEDURE: magnetic resonance|DIAGNOSTIC_TEST: laboratory examination|PROCEDURE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics of IDX719 in Participants With Normal and Impaired Hepatic Function (MK-1894-008)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: IDX719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: fMRI Study Examining Effects of D-cycloserine in Specific Phobia
Status: COMPLETED
Conditions: Phobias
Interventions: DRUG: D-cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Congestion Syndrome Post Tubal Ligation Versus Salpingectomy Performed During Caesarean Section
Status: RECRUITING
Conditions: Pelvic Congestion Syndrome
Interventions: PROCEDURE: salpingectomy during caesarean section|PROCEDURE: tubal ligation during caesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prasugrel and Ticagrelor in ST-segment Elevation Myocardial Infarction
Status: TERMINATED
Conditions: ST-Segment Elevation Myocardial Infarction
Interventions: DRUG: Prasugrel 60 mg|DRUG: Ticagrelor 180 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome
Status: COMPLETED
Conditions: Sjögren Syndrome
Interventions: DRUG: CFZ533|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish Healthcare
Status: COMPLETED
Conditions: Aphasia|Apraxia of Speech|Stroke
Interventions: BEHAVIORAL: MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of speech)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas
Status: RECRUITING
Conditions: LGLL - Large Granular Lymphocytic Leukemia|Primary Cutaneous T-Cell Lymphoma - Category|Primary Cutaneous CD8-Positive Aggressive Epidermotropic T-Cell Lymphoma|Hepatosplenic T-cell Lymphoma|Subcutaneous Panniculitis-Like T-Cell Lymphoma|Aggressive NK Cell Leukemia|Systemic EBV1 T-cell Lymphoma, if CD8 Positive|Hydroa Vacciniforme-Like Lymphoproliferative Disorder|Extranodal NK/T Cell Lymphoma, Nasal Type|Enteropathy-Associated T-Cell Lymphoma|Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma|Indolent Chronic Lymphoproliferative Disorder (CLPD) (CD8+ or NK Derived) of the GI Tract|Other CD8+/NK Cell Driven Lymphoma Not Listed Above
Interventions: DRUG: DR-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nephroprotective Effect of Nicorandil in Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: Nicorandil 10 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Novel Strategy for Early Detection of Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Esophageal Squamous Dysplasia
Interventions: DEVICE: EsophaCap Sponge|PROCEDURE: Chromoendoscopy|DEVICE: EsoCAN assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Omega-3-Index Response to Eating Poultry Foods Naturally Enriched With Omega-3 Polyunsaturated Fatty Acids
Status: RECRUITING
Conditions: Healthy Nutrition|Healthy Adults
Interventions: OTHER: Omega-3 polyunsaturated fatty acid, naturally enriched, poultry foods (chicken-meat and eggs)|OTHER: Control poultry foods (chicken-meat and eggs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children
Status: RECRUITING
Conditions: Behavior Problem
Interventions: DRUG: Dexmedetomidine Hydrochloride|DRUG: Midazolam|DRUG: normal Saline|DRUG: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of PTP-001 (MOTYS) for Symptomatic Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: PTP-001|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose of Diltiazem for Rate Control of Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: low dose diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy (55 Gy/16 Fractions/4 Weeks) for Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RN1001(Avotermin) in Healthy Male Subjects
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Avotermin (RN1001)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pharmacokinetic/Pharmacodynamic (PK/PD) and Safety Evaluation of Oseltamivir [Tamiflu] in the Treatment of Infants 0 to <12 Months of Age With Confirmed Flu Infection
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Tamiflu
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media Navigation Aid Kits for Urinary Incontinence
Status: RECRUITING
Conditions: Urinary Incontinence|Stress Incontinence, Female|Urge Incontinence
Interventions: OTHER: Social Media Navigation Aid Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome
Status: SUSPENDED
Conditions: Myelodysplastic Syndromes|Graft Vs Host Disease|Graft-versus-host-disease
Interventions: DRUG: Busulfan|DRUG: Melphalan|DRUG: Fludarabine|DEVICE: CliniMACS CD34+ enriched, T-cell depleted peripheral blood stem cell (PBSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of DNK333 in Patients With COPD and Cough
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: DNK333 100 mg twice daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Instrument Assisted Soft Tissue Mobilization in Patients With Chronic Mechanical Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain
Interventions: PROCEDURE: Instrument Assisted Soft Tissue Mobilization|PROCEDURE: myofascial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: conventional DMARD combination|BIOLOGICAL: MTX plus anti-TNF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Proof of Concept Study in Patients With Parkinson's Disease and End-of-dose Wearing-off (COMPOC)
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Stalevo|DRUG: levodopa MR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies
Status: COMPLETED
Conditions: Thoracic Neoplasm|Liver Cancer|Ventilator Lung|Radiotherapy; Complications
Interventions: DIAGNOSTIC_TEST: Non-invasive mechanically-assisted ventilation|DIAGNOSTIC_TEST: Dynamic MRI acquisition|DIAGNOSTIC_TEST: Planning 4D-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Weight Loss and Appetite Reduction After Percutaneous Electrical Stimulation Dermatome T6
Status: COMPLETED
Conditions: Weight Loss
Interventions: PROCEDURE: PENS T6|PROCEDURE: TENS T11/T12|DIETARY_SUPPLEMENT: Hypocaloric 1200 Kcal/day diet|DIETARY_SUPPLEMENT: Normocaloric 2000 Kcal/day diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Obesity, Morbid|Brown Fat|Metabolic Disease|Diabetes Mellitus|Insulin Resistance|Abdominal Subcutaneous Fat
Interventions: PROCEDURE: Bariatric surgery|BEHAVIORAL: Dietitian led life style modification intervention|BEHAVIORAL: Conventional care (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: MK-1484|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation After Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Transcutaneous Electric Nerve Stimulation|Pain
Interventions: DEVICE: Transcutaneous electrical nerve stimulation|DEVICE: Continuous passive movement device|OTHER: Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplemental Choline and Brain Development in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Phosphatidylcholine|DIETARY_SUPPLEMENT: Corn oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Does Follow-up With Serum Beta Human Chorionic Gonadotropin (BhCG) Simplify Medical Abortion?
Status: COMPLETED
Conditions: Medical Abortion
Interventions: OTHER: serum BhCG follow-up|OTHER: ultrasonographic follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness and Neuropsychological Predictors of Guided Self-Help for Obsessive-Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: "OCFighter"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis|Postlung Transplant (Bronchiolitis Obliterans)|Chronic Graft Versus Host Disease
Interventions: DRUG: itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Reusable Multifocal Optical Design in a Presbyopic Population
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: senofilcon A Multifocal|DEVICE: senofilcon A Sphere|DEVICE: etafilcon A Multifocal|DEVICE: etafilcon A Sphere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial
Status: RECRUITING
Conditions: MF,PMF,PPV-MF,PET-MF
Interventions: DRUG: Flonoltinib 50mg|DRUG: Flonoltinib 100mg|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Promoting Resilience in Stress Management (PRISM) Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Bone Marrow Neoplasms|Anxiety|Depression|Quality of Life|Adherence, Medication|Coping Skills|Adolescent Behavior
Interventions: BEHAVIORAL: PRISM (Promoting Resilience in Stress Management)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MAP-guided Preemptive Therapy of aGvHD by Ruxolitinib
Status: NOT_YET_RECRUITING
Conditions: GVHD|Acute Stem Cell Transplant Complications
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Relationship Between Executive Function and Diet Adherence in Patients With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Food-related inhibitory control training based on computer|BEHAVIORAL: Non-food-related inhibitory control training based on computer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis (NASH)|Overweight or Obesity
Interventions: DRUG: FT-4101|DRUG: FT-4101 placebo|OTHER: Deuterated Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Leflunomide Efficacy and Hepatotoxicity in Patients With Rheumatoid Arthritis Through Pharmacokinetic and Genetic Approaches
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Leflunomide 20Mg Tab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: APRETUDE|DRUG: Cabotegravir OLI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION