pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BFR DISTRAD: Blood Flow Restricted Training During Rehabilitation Following Distal Radius Fracture Repair
Status: UNKNOWN
Conditions: Distal Radius Fracture|Rehabilitation
Interventions: DEVICE: occlusion training with tourniquet (DELFI PTS ii portable tourniquet system)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of ERY974 in Patients With Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: ERY974|DRUG: Tocilicumab|DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Standard carbon ion beam radiotherapy|RADIATION: Carbon ion beam radiotherapy simultaneously dose boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure After Preserflo / Innfocus Microshunt Implantation vs Trabeculectomy
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma|Pseudoexfoliation Glaucoma
Interventions: DEVICE: Preserflo / Innfocus Microshunt|OTHER: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrate Supplementation and Muscle Blood Flow
Status: COMPLETED
Conditions: Vasodilation|Blood Pressure|Active Hyperemia|Aging
Interventions: DIETARY_SUPPLEMENT: Super Beets|DIETARY_SUPPLEMENT: Beetroot powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
Status: RECRUITING
Conditions: Healthy|Type 2 Diabetes|Obesity
Interventions: DRUG: Dextrose|DRUG: Clinisol 15%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-PD-1 Antibody Combined With Histone Deacetylase Inhibitor in Patients With Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Cervix Cancer|Cervix Neoplasm
Interventions: DRUG: Toripalimab + Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Add-on Effects of Valsartan on Morbi- Mortality (KYOTO HEART Study)
Status: COMPLETED
Conditions: Hypertension|Ischemic Heart Disease|Congestive Heart Failure|Stroke
Interventions: DRUG: Valsartan|DRUG: Non-ARB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tas-102 and Radioembolization With 90Y Resin Microspheres for Chemo-refractory Colorectal Liver Metastases
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer|Liver Metastases
Interventions: DRUG: Tas-102|DEVICE: SIR-Sphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Posterior Composite Tooth Fillings in Adults
Status: COMPLETED
Conditions: Dental Caries|Dental Restoration Failure
Interventions: DEVICE: Filtek One|DEVICE: Filtek Z250
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activator vs the EF Class II Standard in the Treatment of Severe Overjet in Angle Class II Division 1 Malocclusion
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: OTHER: Skeletal, dental, soft tissue index changes in Activator group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Esketamine on Postoperative Sleep Disturbance of Patients Undergoing Spinal Surgery
Status: RECRUITING
Conditions: Esketamine|Sleep Disturbance|Spinal Surgery
Interventions: DRUG: Esketamine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise and Posture in Individuals With Osteoporosis
Status: WITHDRAWN
Conditions: Osteoporosis
Interventions: BEHAVIORAL: Instructional handouts|BEHAVIORAL: Physical therapist instruction and monitoring via teleconferencing|BEHAVIORAL: Web-based instructional videos|BEHAVIORAL: Posture training|BEHAVIORAL: Marching in place
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Recombinant Pichia Pastoris AMA1-DiCo Candidate Malaria Vaccine With GLA-SE and Alhydrogel ® as Adjuvant in Healthy Malaria Non-Exposed European and Malaria Exposed African Adults
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: BIOLOGICAL: Group A1 : 50µg AMA1-DiCo + Alhydrogel|BIOLOGICAL: Group A2 : 50 µg AMA1-DiCo+ GLA-SE|BIOLOGICAL: Group B2 : Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Services Integration in Gynecological Oncology Clinics
Status: COMPLETED
Conditions: Gynecologic Oncology Patient
Interventions: BEHAVIORAL: Integrated psychological care|OTHER: Surveys|PROCEDURE: Blood draw|PROCEDURE: Fresh tissue from ovary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia
Status: RECRUITING
Conditions: Fetal Hemoglobin|Thalassemia Major|Genetic Disease
Interventions: DRUG: Thalidomide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adalimumab Intralesional in Intestinal Strictures of Crohn's Disease Patients
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Adalimumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation Therapy in Schizophrenia: Effects on Epigenetics
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Remediation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Thrombus on Transesophageal Echocardiography
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Flutter|Transesophageal Echocardiography|Ablation|Cardioversion|Thrombus; Embolism
Interventions: DIAGNOSTIC_TEST: Transesophageal echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Claudication Severity on Functional Outcomes
Status: RECRUITING
Conditions: Intermittent Claudication
Interventions: OTHER: Pain Free Exercise (PF)|OTHER: Moderate Claudication Pain Exercise (MOD-P)|OTHER: Maximal Claudication Pain Exercise (MAX-P)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Glucose Response to Meals of Varying Glycemic Index in Youth With Type 1 & 2 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes|Impaired Glucose Metabolism
Interventions: BEHAVIORAL: Diet|OTHER: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: XR-NTX (Extended-Release Naltrexone)|DRUG: Oral Naltrexone (O-NTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-man Trial of NNC0142-0002 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: placebo|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: NNC0142-0002|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Icaritin Soft Capsule Versus Huachansu Tablet in the First-line Treatment of Unresectable Hepatocellular Carcinoma With Poor Conditions and Biomarker Enrichment (Biomarker Enrichment Study of Poor Prognosis HCC Patients, BESTPOP)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Icaritin|DRUG: Huachansu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics
Status: COMPLETED
Conditions: Primary Hyperparathyroidism
Interventions: DEVICE: Fluobeam(TM) Imaging System (Fluoptics)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEAVE Safe With DOACs
Status: COMPLETED
Conditions: Cardiovascular Diseases|Venous Thromboembolism|Atrial Fibrillation|Bleeding|Stroke
Interventions: OTHER: Clinical Pharmacist Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Physiological, Behavioural and Subjective Measures of Listening Effort
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid without NR enabled|DEVICE: Hearing Aid with NR(1)|DEVICE: Hearing Aid with NR(2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paradigm I Clinical Trial: Study of the PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemia Attack or Paradoxical Embolism
Status: UNKNOWN
Conditions: Patent Foramen Ovale
Interventions: DEVICE: PFX Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Compare the Effect of Insulin Degludec and Insulin Glargine on Blood Sugar Levels in People With Type 2 Diabetes - the SWITCH PRO Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec|DRUG: Insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study
Status: RECRUITING
Conditions: Primary Open Angle Glaucoma
Interventions: DRUG: Dietary supplements - Nicotinamide and Pyruvate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of Maintenance Treatment of Apatinib in Advanced Gastric Cancer Patients Have Completed Postoprative Adjuvant Chemotherapy
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib Mesylate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rib Microtia and the Erector Spinae Plane (ESP) Block
Status: NOT_YET_RECRUITING
Conditions: Microtia, Congenital|Microtia|Anesthesia, Local|Anesthesia
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urine Albendazole Levels for Coverage Assessment
Status: COMPLETED
Conditions: Helminthiasis
Interventions: DRUG: Albendazole Pill|OTHER: High fat content diet|OTHER: Moderate fat content die
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term Intraocular Lens (IOL) Decentration and Tilt in Eyes With Pseudoexfoliation Syndrome (PES) Following Cataract Surgery
Status: COMPLETED
Conditions: Cataract|Pseudoexfoliation Syndrome|Pseudophakia
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Avatar Therapy in Comparison to Cognitive Behavioral Therapy for Treatment-resistant Schizophrenia
Status: COMPLETED
Conditions: Auditory Hallucination, Verbal|Treatment-resistant Schizophrenia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Avatar Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Tolerability, Steady-state Pharmacokinetics and Erythrocyte COMT Inhibition of BIA 3-202
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Nebicapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transdiagnostic Individual Behavioral Activation and Exposure Therapy
Status: RECRUITING
Conditions: Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Individual Behavioral Activation Therapy (IBAT)|BEHAVIORAL: The PASCET Program for Youth Depressive Disorders|BEHAVIORAL: The Coping Cat Program for Youth Anxiety Disorders|OTHER: 14-week waitlist (WL) condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Interchangeability of ABP 654 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Ustekinumab|DRUG: ABP 654
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Treatment of Diabetic Foot Ulcers Using a Nitric Oxide Releasing Patch: PATHON
Status: COMPLETED
Conditions: Diabetic Foot
Interventions: DRUG: Controlled nitric oxide releasing patch|DRUG: placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different SARS-CoV-2 Vaccine Schedules and Vaccination Intervals on Reactogenicity and Humoral Immunogenicity
Status: COMPLETED
Conditions: SARS-CoV2 Infection|Immunisation Reaction|Antibody Hypersensitivity|Tolerance
Interventions: DRUG: IM injection of vaccination (mRNA vaccination)|DRUG: IM injection of vaccination (vector based vaccination)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Covid-19, Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) and Influenza Treatment System With Machine Learning
Status: COMPLETED
Conditions: COVID-19|Post-COVID-19 Syndrome|Influenza
Interventions: OTHER: Autonomous Treatment System for Covid-19, Post-Acute Sequelae of SARS-CoV-2 Infection and Influenza Based on Machine Learning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cetuximab in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: cetuximab|GENETIC: molecular diagnostic method|OTHER: immunologic technique|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Performance of Two Monthly Replacement Toric Soft Contact Lenses
Status: COMPLETED
Conditions: Ametropia|Astigmatism
Interventions: DEVICE: Lehfilcon A toric contact lenses|DEVICE: Comfilcon A toric contact lenses|DEVICE: CLEAR CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Doses of Dexmedetomidine on Cerebral Oxygen Saturation and Postoperative Anxiety in Elderly Patients
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Hypotonic Treprostinil Subcutaneous Infusion for Control of Treprostinil Related Site Pain
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: HypotonicTreprostinil Solution|DRUG: Eutonic Treprostinil Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EVAluation of the Non Inferiority of Interpretability of Cardiokin Compared to Holter
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Cardioskin|DEVICE: Holter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: [14C-ETC-1002]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile Messages Affects Adherence of Stent Removal or Exchange in Patients With Benign Pancreaticobiliary Diseases
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: short message service group|OTHER: conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of STR001-IT and STR001-ER in Patients With SSHL
Status: COMPLETED
Conditions: Acute Hearing Loss
Interventions: DRUG: STR001-IT and STR001-ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of Kaletra Soft-Gel Capsules and Kaletra Tablets in an African American Cohort
Status: COMPLETED
Conditions: HIV-1|AIDS
Interventions: DRUG: Kaletra soft-gel capsules switched to Kaletra tablets|DEVICE: MOS-HIV Health and Medication Satisfaction Survey, Global Conditioning Improvement and Therapy Preference Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetic Trial in Healthy HIV-Negative Women to Assess the Delivery of Dapivirine From a Vaginal Ring
Status: COMPLETED
Conditions: HIV Infections
Interventions: COMBINATION_PRODUCT: Dapivirine Vaginal Ring|COMBINATION_PRODUCT: Placebo vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: LN-RADS, RECIST 1.1 and Node-RADS Classification in the Assessment of Lymph Nodes
Status: RECRUITING
Conditions: Lymph Node Neoplasm|Lymph Node Metastasis
Interventions: OTHER: Lymph node assessment according to RECIST 1.1 in CT|OTHER: Lymph node assessment according to Node-RADS in CT|OTHER: Lymph node assessment according to LN-RADS in CT|OTHER: Lymph node assessment according to RECIST 1.1 in MRI|OTHER: Lymph node assessment according to Node-RADS in MRI|OTHER: Lymph node assessment according to LN-RADS in MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Potent Antiviral Therapy for Critically Ill HIV Infected Patients Admitted to Intensive Care
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Nelfinavir mesylate|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial Investigating the Efficacy and Safety of a Vaginal Insert in Pregnant Women at Term
Status: COMPLETED
Conditions: Cervical Ripening
Interventions: DRUG: Dinoprostone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test Lung Stretch Therapy (Hyperinsufflation) in Children With Collagen VI Muscular Dystrophy
Status: COMPLETED
Conditions: Congenital Muscular Dystrophy
Interventions: OTHER: Hyperinsufflation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Impact of Admission With Covid-19 During the SARS-CoV-2 Pandemic: Naturalistic Cohort Study With a Digital Intervention
Status: UNKNOWN
Conditions: Anxiety Disorders|Post Traumatic Stress Disorder|Depressive Disorder|Covid19
Interventions: OTHER: Feeling Good Digital App
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial to Assess Vitamin D Requirements in Lactating Women
Status: COMPLETED
Conditions: Vitamin D Deficiency|Vitamin D Insufficiency
Interventions: DIETARY_SUPPLEMENT: 20µg Vitamin D3|DIETARY_SUPPLEMENT: 20µg Vitamin D3 + 500 mg Calcium|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 68Ga-FAPI-04 PET Imaging in Early Response Evaluation of Rectal Cancer Patients Treated With Immunotherapy
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: 68Ga-FAPI-04|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study for IFE4PrEP Intervention on PrEP Uptake by Southern African American Women
Status: COMPLETED
Conditions: HIV Prevention
Interventions: BEHAVIORAL: Gain framing plus demographically targeted photos|BEHAVIORAL: Loss framing plus demographically targeted photos|BEHAVIORAL: Gain framing plus not demographically targeted photos|BEHAVIORAL: Loss framing plus not demographically targeted photos
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Azacitidine Combined With Venetoclax in Previously Untreated Higher-risk Myelodysplastic Syndromes
Status: RECRUITING
Conditions: Untreated Myelodysplastic Syndrome
Interventions: DRUG: Onureg + Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot-Assisted Minimally Invasive Surgery for Brainstem Hemorrhage
Status: NOT_YET_RECRUITING
Conditions: Brain Stem Hemorrhage|Robotic Surgical Procedures|Stereotactic Techniques
Interventions: PROCEDURE: Robot-Assisted Stereotactic Brainstem Hematoma Puncture|DRUG: Conservative non-surgical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Front-of-Package Nutrition Labels
Status: NOT_YET_RECRUITING
Conditions: Nutrition|Food Selection|Food Preferences|Dietary Habits|Healthy Diet
Interventions: BEHAVIORAL: Positive Labels|BEHAVIORAL: Spectrum Labels|BEHAVIORAL: FDA High In Labels|BEHAVIORAL: FDA Traffic Light Labels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Semi-vegetarian Diet in Inflammatory Bowel Disease Patients With Clinical Remission
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Calprotectin|Fecal Microbiota|Vegetarian Diet
Interventions: OTHER: Semi-vegetarian diet and increase fiber consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Chemotherapy Plus Toripalimab for Epstein-Barr Virus-associated Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Adenocarcinoma of the Stomach|Adenocarcinoma of Esophagogastric Junction|Epstein-Barr Virus-Associated Gastric Carcinoma
Interventions: DRUG: Toripalimab|DRUG: Oxaliplatin|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melphalan and Radiation Therapy Followed By Lenalidomide in Treating Patients Who Are Undergoing Autologous Stem Cell Transplant for Stage I, Stage II, or Stage III Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma|Smoldering Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: RADIATION: total marrow irradiation|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation|BIOLOGICAL: filgrastim|GENETIC: fluorescence in situ hybridization|GENETIC: cytogenetic analysis|DRUG: cyclophosphamide|PROCEDURE: autologous-autologous tandem hematopoietic stem cell transplantation|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endogenous Glucoseproduction in Patients With Type 2 Diabetes Mellitus During Oral Glucose and iv. Glucose Infusion
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BIOLOGICAL: isoglycemic intravenous glucose infusion and Glucagon infusion, day C|BIOLOGICAL: Oral glucose tolerance test, day A|BIOLOGICAL: intravenous iv glucose infusion, day B
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib Tosylate, Cisplatin, and Docetaxel in Treating Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary
Interventions: DRUG: sorafenib tosylate|DRUG: cisplatin|DRUG: docetaxel|OTHER: Correlative Studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epigenetics and MDMA-Assisted Psychotherapy for PTSD
Status: ACTIVE_NOT_RECRUITING
Conditions: PTSD
Interventions: DRUG: MDMA|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: S8809-S9800-S9911-S9704-A Study of Blood and Tissue Samples From Patients With Follicular Lymphoma Treated With Rituximab, Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine, and Prednisone
Status: COMPLETED
Conditions: Lymphoma
Interventions: GENETIC: DNA analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients
Status: COMPLETED
Conditions: Parkinsonian Syndrome|Parkinson Disease(PD)|Multiple System Atrophy (MSA)|Progressive Supranuclear Palsy (PSP)|Essential Tremor
Interventions: DRUG: DaTSCAN™ Ioflupane (123I) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
Status: TERMINATED
Conditions: Schizophrenia|Memory Disorders|Cognition Disorders
Interventions: DRUG: Atomoxetine|PROCEDURE: Functional magnetic resonance imaging|PROCEDURE: Neuropsychological Testing|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation With Percutaneous Electrical Nerve Field Stimulation for Adults With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DEVICE: Auricular percutaneous neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis|Portal Hypertension|Variceal Hemorrhage|Bleeding|Esophageal and Gastric Varices
Interventions: DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
Status: UNKNOWN
Conditions: Combination of General Anesthesia to Spinal and Epidural Techniques
Interventions: DEVICE: spinal-epidural device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Aprepitant in Autologous Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Vomiting
Interventions: DRUG: Tropisetron|DRUG: Dexamethasone|DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-Palliative Care Intervention for Patients With Chronic Graft-Versus-Host Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Graft-versus-host Disease|Chronic GVHD|cGVHD
Interventions: OTHER: Tele-palliative care visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot
Status: COMPLETED
Conditions: Ankle and or Hindfoot Injury
Interventions: OTHER: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RH-1 in Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Advanced Solid Tumors|Non-Hodgkin's Lymphoma
Interventions: DRUG: RH-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Intubation With Difficult Airway
Status: UNKNOWN
Conditions: Trauma|Intubation, Endotracheal
Interventions: DEVICE: MAC|DEVICE: Coopdech|DEVICE: AirTraq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|Hepatocellular Carcinoma|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: cemiplimab|DRUG: Platinum Doublet|DRUG: fianlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Delayed Cord Clamping and Milking on the Amount of Stem Cells In Preterm
Status: UNKNOWN
Conditions: Umbilical Cord; Clamping Time
Interventions: PROCEDURE: Delayed umbilical cord clamping|PROCEDURE: Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Assess the Effects of Brolucizumab in Adult Patients With Neovascular Age Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age Related Macular Degeneration
Interventions: DRUG: RTH258/Brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study to Evaluate the Drug Interaction Between SHR0302 and CYP Substrates in Healthy Volunteers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: SHR0302 Tablets|DRUG: Midazolam Maleate Tablets|DRUG: Warfarin Sodium Tablets|DRUG: Omeprazole Enteric Capsules|DRUG: Vitamin K1 Tablets|DRUG: Repaglinide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Therapeutic Music Combined With Loaded Sit-to-Stand Resistance Exercise for Children With Spastic Diplegia
Status: COMPLETED
Conditions: Cerebral Palsy|Paraparesis, Spastic
Interventions: BEHAVIORAL: Loaded sit-to-stand exercise|BEHAVIORAL: Synchronized music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
Status: UNKNOWN
Conditions: Physical Activity|Obesity|Children|Academic Underachievement Disorder|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: MOVI-KIDS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nebido Versus Placebo in Elderly Men With Typical Symptoms of Late Onset Hypogonadism Over a Period of 54 Weeks
Status: WITHDRAWN
Conditions: Hypogonadism
Interventions: DRUG: NEBIDO|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Nutrient Supplementation in High-intensity Functional Training
Status: COMPLETED
Conditions: Exercise Training|Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Fish nutrients|DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of the I-gel Laryngeal Mask and the Classic Laryngeal Mask in Patients With a BMI>25
Status: COMPLETED
Conditions: Surgery|Intubation
Interventions: DEVICE: I-gel|DEVICE: LMA-Unique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexamethasone for Ropivacaine Axillary Block
Status: COMPLETED
Conditions: Postoperative Pain|Anesthesia|Forearm Injuries
Interventions: DRUG: intravenous dexamethasone|DRUG: intravenous placebo|DRUG: perineural ropivacaine|OTHER: ultrasound guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injections Versus Glucagon Like Peptide 1 Receptor Agonist in Weight Loss
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions
Status: WITHDRAWN
Conditions: Corneal Neovascularization|Corneal Graft Failure|Anterior Segment Inflammation
Interventions: DRUG: Gamunex-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Program Using Ride-on Toys to Improve Upper Extremity Function in Children With Hemiplegia
Status: RECRUITING
Conditions: Hemiplegia|Cerebral Palsy|Children, Only
Interventions: DEVICE: SPEED Training|BEHAVIORAL: CRAFT Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Training and Isoflavone Supplementation On Pelvic Floor in Women in the Postmenopausal Period
Status: COMPLETED
Conditions: Pelvic Floor
Interventions: OTHER: Exercise|OTHER: isoflavone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: HoPe: Home Treatment and Peer Support for Acute Mental Health Crisis
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Mental Health Condition With Indication of Hospital Admission
Interventions: BEHAVIORAL: Home Treatment with Peer Support|BEHAVIORAL: Home Treatment without Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: COMBINATION_PRODUCT: EZ 10 mg/Ator 10 mg|COMBINATION_PRODUCT: EZ 10 mg/Ator 20 mg|DRUG: Atorvastatin|DRUG: Placebo for FDC EZ/Ator|DRUG: Placebo for atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Reduce Perceived Cognitive Impairment in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Neuropsychological Feedback & Psychoeducation (Cognition)|BEHAVIORAL: Psychoeducation (Health)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pannus Retraction for Ultrasound Evaluation of the Obese Gravida: A Pilot Study
Status: COMPLETED
Conditions: Obesity|Pregnancy Complications|Fetal Anomaly|Pannus
Interventions: DEVICE: traxi® Panniculus Retractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Treatment in Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: RADIATION: External Beam Radiation|DRUG: Gemcitabine neoadjuvant|PROCEDURE: Surgery|DRUG: Gemcitabine adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ASEA on Energy Expenditure and Fat Oxidation in Humans
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Salt Water|DIETARY_SUPPLEMENT: ASEA water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Restasis for Treatment of Brittle Nails
Status: COMPLETED
Conditions: Brittle Nails
Interventions: DRUG: Restasis (cyclosporine ophthalmic emulsion) 0.05%|DRUG: Refresh® Dry Eye therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Pemigatinib in Patients With Advanced Malignancies With FGF/FGFR Alterations
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.
Status: RECRUITING
Conditions: Retinitis Pigmentosa|Cone Dystrophy|Usher Syndromes|Retina; Dystrophy
Interventions: DIAGNOSTIC_TEST: Retina Analysis-mosaic|DIAGNOSTIC_TEST: Autofluorescence|DIAGNOSTIC_TEST: OCT- 1 micra|PROCEDURE: Genotype analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RAD001 in Pheochromocytoma or Nonfunctioning Carcinoid
Status: COMPLETED
Conditions: Pheochromocytoma|Extra-adrenal Paraganglioma|Non-functioning Carcinoid
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Hypofractionated Radiotherapy in the Treatment of Malignant Pleural Mesothelioma
Status: RECRUITING
Conditions: Malignant Pleural Mesothelioma
Interventions: RADIATION: Accelerated hypofractionation with Tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Real-time Feedback on Physical Activity Patterns in Flemish Employees
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: DEVICE: SenseWear display|DEVICE: Pedometer|DEVICE: SenseWear Armband|BEHAVIORAL: Personal Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ABT-267 in Both Healthy Volunteers and Hepatitis C Virus (HCV) Genotype 1 Infected Subjects
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ABT-267|DRUG: Placebo|PROCEDURE: Blood Sample Collection|DRUG: Cytochrome P450 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled, Randomized, Safety and Efficacy Study to Evaluate the Change in Hemoglobin A1c Levels in Type 2 Diabetic Subjects While Taking Nutralin
Status: WITHDRAWN
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: Nutralin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the Traditional Chinese Medicine Fangji Huangqi Pill Combined With Mobic on Active Knee Osteoarthritis
Status: UNKNOWN
Conditions: Fangji Huangqi Pill|Knee Osteoarthritis
Interventions: DRUG: Fangji Huangqi pill or Fangji Huangqi pill placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole for Treatment of GERD in Pediatric Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)|Erosive Esophagitis|Non-erosive Esophagitis
Interventions: DRUG: Esomeprazole (Nexium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Unilateral Right, Unilateral Left and Bilateral Applications of Transcutaneous Auricular Vagus Nerve Stimulation on Autonomic Nervous System Activity in Healthy People
Status: UNKNOWN
Conditions: Health, Subjective
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC)
Status: RECRUITING
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Etoposide, doxorubicin, cisplatin and Mitotane plus Megestrol Acetate 160 MG|DRUG: Etoposide, doxorubicin, cisplatin and Mitotane plus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT