pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mindfulness Based Resilience Training
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: MBRT ClassRoom and Phone Application|BEHAVIORAL: Phone application only|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of Protective Stoma After Primary Anastomosis for Generalized Peritonitis Due to Perforated Diverticulitis
Status: RECRUITING
Conditions: Peritonitis
Interventions: PROCEDURE: Primary anastomosis without protective stoma|PROCEDURE: Anastomosis with protective stoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Cetuximab in Treating Patients With Liver Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gum Chewing And Bowel Motility in Patients Undergoing Cesarean Section. Kasr el Ainy Experience
Status: UNKNOWN
Conditions: Gum Chewing|Bowel Function
Interventions: BIOLOGICAL: sugarless gum|OTHER: traditional management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Stroke Patients' Outpatient Rehabilitation Therapy (SPORT)
Status: COMPLETED
Conditions: Stroke|Incentives|Stroke Rehabilitation
Interventions: BEHAVIORAL: Transportation incentives|BEHAVIORAL: Transportation and rehabilitation services incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Study of Pembrolizumab With Entinostat to Treat Metastatic Melanoma of the Eye
Status: COMPLETED
Conditions: Metastatic Uveal Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Entinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: levodopa/carbidopa/entacapone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Tumor Biopsy-driven Study to Understand the Relationship Between Biomarkers and Clinical Response in Patients With Head and Neck Cancer Receiving REGN2810 (Anti-PD-1)
Status: COMPLETED
Conditions: Recurrent Squamous Cell Carcinoma of Head|Recurrent Squamous Cell Carcinoma of Neck|Metastatic Squamous Cell Carcinoma of Head|Metastatic Squamous Cell Carcinoma Neck
Interventions: DRUG: REGN2810
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome
Status: RECRUITING
Conditions: Obstructive Defecation Syndrome|Chronic Constipation|Rectal Prolapse
Interventions: PROCEDURE: Modified Laparoscopic Ventral Mesh Rectopexy|PROCEDURE: Modified Laparoscopic Ventral Mesh Rectopexy Combined with Stapled Trans-anal Rectal Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants
Status: WITHDRAWN
Conditions: Hepatic Impairment
Interventions: DRUG: TNO155
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ivermectin Nasal Drops in Post COVID-19 Parosmia
Status: UNKNOWN
Conditions: Parosmia
Interventions: DRUG: Ivermectin Topical|DRUG: Budesonide Nasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of ctDNA for NED Status in mCRC and Its Utility in Guiding Therapeutic Intervention
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|No Evidence of Disease Status|ctDNA Monitoring
Interventions: OTHER: ctDNA and adjuvant therapy|OTHER: ctDNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With Refractory Focal Epilepsy
Status: NOT_YET_RECRUITING
Conditions: Focal Onset Seizures
Interventions: DRUG: RAP-219
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Analgesia for Bladder Botox Injections
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence|Urinary Incontinence, Urge|Overactive Bladder
Interventions: DRUG: Phenazopyridine|DRUG: 1% lidocaine with sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interface Selection for Adaptive Servo Ventilation
Status: RECRUITING
Conditions: Central Sleep Apnea|ASV
Interventions: DEVICE: Switch from oronasal to nasal mask during ASV treatment|DEVICE: Switch from nasal to oronasal mask during ASV treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Breast Cancer
Interventions: DRUG: 99mTc-NTP 15-5 at a diagnostic activity of 5 MBq/kg|DRUG: 99mTc-NTP 15-5 at a diagnostic activity of 10 MBq/kg|DRUG: 99mTc-NTP 15-5 at a diagnostic activity of 15 MBq/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation
Status: COMPLETED
Conditions: Tuberculosis|Tuberculosis, Pulmonary
Interventions: DRUG: PBTZ169 Formulation|DRUG: Placebo|DRUG: PBTZ169 NCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wildtype or Unknown Non-Squamous NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Selumetinib|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Amlodipine/Atorvastatin Co-Administration To Amlodipine Alone In Patients With Hypertension And Dyslipidemia
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: atorvastatin|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study in Healthy Volunteers to Investigate the Cross-talk Between Local Drug Concentrations in the Skin and Systemic Concentrations During Topical Bioequivalence Studies Using Dermal Sampling Techniques
Status: COMPLETED
Conditions: Healthy|Dermal Pharmacokinetic Measurement
Interventions: PROCEDURE: Intravenous infusion of lidocaine|DRUG: Lidocaine 2.5% and Prilocaine 2.5% cream", USP (2.5% lidocaine, 2.5% prilocaine, Actavis Pharma incorporated, USA)|DRUG: Lidocorit 2%-Ampullen" (Gebro Pharma Gesellschaft mit beschränkter Haftung, Austria)|DEVICE: Dermal open flow microperfusion|DEVICE: Dermal Microdialysis|PROCEDURE: Blood sampling in dermal sampling visit|PROCEDURE: Blood sampling in clearance visit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Validation Study in Allergic Conjunctivitis to Birch Pollen During Allergen Challenge in ALYATEC EEC
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: OTHER: Exposure to birch pollen in EEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness and Safety of Chinese Medicine to Treat Hand, Foot, and Mouth Disease
Status: COMPLETED
Conditions: Hand, Foot, and Mouth Disease
Interventions: DRUG: Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge)|DRUG: Xiyanping injection plus western therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Risk-adapted Treatment for T-lineage ALL of Young Adults (18-59 Years Old)
Status: RECRUITING
Conditions: T-cell Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Longitudinal Study of Patients With Idiopathic Pulmonary Arterial Hypertension, Family or Taking Anorectics
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: PROCEDURE: Right Heart Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Double-blind and Placebo-controlled Study on Intervention Effect of Medium and Long Chain Fatty Acid Triglyceride on Glycolipid Homeostasis in Patients With Metabolic Syndrome and Mechanisms
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: MLCT supplementation|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single Dose Safety Study of Quadrivalent HPV Vaccine in Chinese Female Subjects (V501-035)
Status: COMPLETED
Conditions: HPV Infections
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy of Herbal Medicine (Shaoyao Gancao Decoction Jiawei) in Sleep-related Leg Cramps
Status: COMPLETED
Conditions: Sleep-related Leg Cramps
Interventions: DRUG: Shaoyao Gancao Decoction Jiawei
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19-CAR-T Cells in Subjects With Relapsed/Refractory B Cell Malignancies
Status: RECRUITING
Conditions: B-Cell Malignancy
Interventions: GENETIC: Anti-CD19-CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study To Compare The Effect of Panzyga Versus Placebo in Patients With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS/PANDAS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Acute-Onset Neuropsychiatric Syndrome
Interventions: BIOLOGICAL: Panzyga|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Description and Modeling of Swallowing Disorders After a Stroke
Status: UNKNOWN
Conditions: Stroke|Swallowing Disorders
Interventions: OTHER: Neurological evaluation|OTHER: Laryngological evaluation|OTHER: MRI evaluation|OTHER: Breathing investigation|OTHER: MRI and articulatory investigation|OTHER: Postural investigation|OTHER: Voice and soundscape investigation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Omalizumab in Adults (18-60 Years of Age) With Moderate-Severe, Persistent Allergic Asthma, Despite Receiving Inhaled Corticosteroids and Long Acting Beta-agonists
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: omalizumab at a dose of 0.016mg/kg/IU/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Articaine and Lidocaine in Extraction of Wisdom Teeth of Upper and Lower Jaws
Status: ENROLLING_BY_INVITATION
Conditions: Wisdom Tooth|Dental Impaction
Interventions: DRUG: Different dental anesthetic agents during wisdom tooth surgery (Orabloc®, Octocaine®, and Xylestesin-A®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Laboratory-Treated Autologous Lymphocytes and Aldesleukin After Cyclophosphamide and Fludarabine in Treating Patients With Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: Tumor Infiltrating Lymphocytes (TIL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Efficacy and Safety of AKST4290 in Subjects With Parkinson's Disease on Stable Dopaminergic Treatment
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: AKST4290|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategies for IgG4-RD Patients With Superficial Organ Involvement
Status: RECRUITING
Conditions: Autoimmune Diseases
Interventions: DRUG: Diprospan plus iguratimod|DRUG: Diprospan plus leflunomide|DRUG: Prednisone plus leflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of the Risk of Complete Sternotomy Scar Dehiscence in Cardiac Surgery: A Clinical Investigation Comparing Negative Pressure Wound Therapy (NPWT) vs. Standard Dressing
Status: RECRUITING
Conditions: Complete Vertical Midline Sternotomy / Cardiac Surgery
Interventions: DEVICE: Dressing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) Radioligand
Status: TERMINATED
Conditions: Dementia
Interventions: DRUG: 11C-ER176|DRUG: 11C-PIB|DIAGNOSTIC_TEST: Positron Emission Tomography (PET) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Systolic Heart Failure|Myocardial Disease|Cardiomyopathy
Interventions: DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Cervical Spine Surgery
Status: RECRUITING
Conditions: Spine Fusion|Spine Disease|Spinal Disease
Interventions: DRUG: 0.9%sodium chloride|DRUG: 0.2% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALG-125755 to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single Doses in Healthy Volunteers, and Single and Multiple Doses in CHB Subjects
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ALG-125755|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Acne
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: DIETARY_SUPPLEMENT: D Max Drops|DRUG: Azithromycin 250 milligram Oral Capsule|DRUG: Adapalene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nivolumab vs Placebo in Patients With Acute Myocardial Infarction: A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Acute Anterior ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Nivolumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partially Replicate Bioequivalence Study of Quetiapine 25 mg in Healthy Volunteers Under Fasting Condition
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test product (T) 25 mg Film Coated Tablets|DRUG: Reference product (R) 25 mg Film Coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Linking Inter-professional Newborn and Contraception Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Family Planning|Contraception|PostPartum
Interventions: BEHAVIORAL: LINCC intervention - enable co-schedule feature
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Test the Phototoxicity of Sunscreen Products
Status: COMPLETED
Conditions: Sunscreen Agents
Interventions: DRUG: SPF 50 Y65 110 (BAY987519)|DRUG: SPF 50 Y51 002 (BAY987519)|DRUG: SPF 15 V27 104 (BAY987519)|DRUG: Sodium chloride [NaCl]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Maintenance Therapy: Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Maintenance lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AIMIGo 12L ECG Synthesis Software Pivotal Study for Arrythmia Detection
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation|Atrial Flutter|Bradycardia|Tachycardia
Interventions: DEVICE: Vectorcardiography (VECG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Efficacy Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: MSI-1256F (Squalamine Lactate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Intracerebral Hemorrhage|Cerebral Edema|Stroke Hemorrhagic|Intracerebral Hemorrhage, Hypertensive|Intracerebral Hemorrhage Intraparenchymal
Interventions: DRUG: Fingolimod 0.5 mg|DRUG: Placebo|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2
Status: RECRUITING
Conditions: COVID-19|SARS CoV 2 Infection
Interventions: OTHER: Survey|OTHER: Medical History Review|OTHER: Sample Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1/II, Safety and Immunogenicity Study of AERAS-404 in BCG-Primed Infants
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: AERAS-404|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simultaneous Corneal Wavefront-Guided Trans-PRK and Corneal Collagen Crosslinking After ICRS Implantation for Moderate Keratoconus
Status: COMPLETED
Conditions: Moderate Keratoconus
Interventions: PROCEDURE: combined corneal wavefront-guided transepithelial photorefractive keratectomy (tPRK)|PROCEDURE: accelerated corneal collagen cross-linking (CXL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Hyper CVAD Protocol (Standard of Care Multi-Agent Chemotherapy)|DRUG: Calaspargase Pegol|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of High Tone Power Therapy on Spasticity and Gait Kinematics in Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DEVICE: high tone power therapy|DEVICE: transcutaneous electrical nerve stimulation (TENS)|OTHER: selected physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Rivaroxaban and Aspirin in PAD After Endovascular Revascularization
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Rivaroxaban and Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib
Status: COMPLETED
Conditions: Colorectal Neoplasms|Gastrointestinal Stromal Tumors
Interventions: DRUG: Esomeprazole 40mg concomitantly|DRUG: Esomeprazole 40mg before|DRUG: Regorafenib 160mg or 120mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Anesthesia to Reduce Incidence of Postoperative Delirium
Status: UNKNOWN
Conditions: Postoperative Delirium
Interventions: DEVICE: Bispectral index, as measured by a BIS processor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using ROMIPLOSTINE for Persistent Thrombocytopenia With Transfusion-dependent Patients Who Received Allogeneic Hematopoietic Stem Cell
Status: COMPLETED
Conditions: Persistent Thrombocytopenia Following Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Interventions: DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamics of the Immune Response in Children to the 23-valent Pneumococcal Capsular Polysaccharide Vaccine (Pneumovax)
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: Pneumovax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Post-Transplant Low-Dose Inotuzumab Ozogamicin to Prevent Relapse of Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Acute Lymphoid Leukemia
Interventions: DRUG: Inotuzumab ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Cutaneous Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: Autologous Dendritic Cells loaded with MAGE-A3, MelanA and Survivin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: LY900014|DRUG: Insulin Lispro|DRUG: Insulin Glargine|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: AAV2/5-hPDE6B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Methylnaltrexone|OTHER: Placebo|DRUG: Morphine|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel School-clinic-community Online Model of Child Obesity Treatment in Singapore During COVID-19
Status: COMPLETED
Conditions: Pediatric Obesity|Clinical Trial
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: online KKH Sports Singapore Program with Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexamethasone on Supraclavicular Brachial Plexus Block for Shoulder Arthroscopy
Status: COMPLETED
Conditions: Shoulder Arthroscopy|Pain
Interventions: DRUG: IV Saline|DRUG: IV Dexamethasone 4mg|DRUG: IV Dexamethasone 6mg|DRUG: IV Dexamethasone 8mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease?
Status: RECRUITING
Conditions: Rumination|Depressive Symptoms|Blood Pressure
Interventions: BEHAVIORAL: Rumination-Focused Cognitive Behavior Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC73077 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: HEC73077 tablets|DRUG: HEC73077 placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab (Lucentis) for Polypoidal Choroidal Vasculopathy
Status: COMPLETED
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: ranibizumab 0.5 or 0.3 mg/0.05 cc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children
Status: COMPLETED
Conditions: Benign Childhood Epilepsy With Centro-Temporal Spikes
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chewed vs. Crushed Lanthanum Carbonate in Hemodialysis Patients
Status: COMPLETED
Conditions: Hyperphosphatemia|Kidney Disease
Interventions: DRUG: Lanthanum Carbonate Chewable Product|DRUG: Lanthanum carbonate crushed powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Linagliptin (BI 1356) in Black/African Americans With Type 2 Diabetes With a MTT Sub-study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Linagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)
Status: RECRUITING
Conditions: Type 2 Diabetes|Chronic Inflammation|Intestinal Permeability
Interventions: DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surufatinib Combined With Serplulimab Plus Chemotherapy in the Treatment of Extensive-stage Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Surufatinib,Serplulimab,Etoposide,Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of NanO2(TM) Combined With Radiation and Temozolomide in Patients With Newly Diagnosed GBM
Status: RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: NanO2TM|DRUG: Placebo Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Radiofrequency Ablation of the Genicular Nerve Versus Physical Therapy for Chronic Knee Osteoarthritis
Status: RECRUITING
Conditions: Chronic Knee Osteoarthritis
Interventions: OTHER: radiofrequency ablation|OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration Effect of Local Anesthetics on Femoral Nerve Block Efficiency
Status: COMPLETED
Conditions: Anesthesia, Conduction|Arthroplasty, Replacement, Knee|Pain, Postoperative|Anesthesia and Analgesia
Interventions: PROCEDURE: Ultrasound Guided Femoral Nerve Block|OTHER: Dressing|DRUG: Bupivacaine 0.25% Injectable Solution|DRUG: Bupivacaine 0.125% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a French-version of the Leeds Food Preference Questionnaire in Normal Weight and Patients With Obesity
Status: TERMINATED
Conditions: Normal Weight Adults|Adults With Obesity
Interventions: BEHAVIORAL: Visit 1|BEHAVIORAL: Visit 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department
Status: COMPLETED
Conditions: Migraine
Interventions: BEHAVIORAL: PMR (Progressive muscle relaxation therapy)|BEHAVIORAL: Monitored Usual Care (MUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PI3Kβ Selective Inhibitor With Paclitaxel, Advanced Gastric Adenocarcinoma
Status: COMPLETED
Conditions: Advanced Gastric Adenocarcinoma
Interventions: DRUG: GSK2636771|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthetic Infiltration or Erector Spina Plan Block on Stress Hormone Response
Status: COMPLETED
Conditions: Post Operative Pain|Erector Spinae Plane Block|Inguinal Hernia
Interventions: PROCEDURE: wound site local anesthesic infiltration|PROCEDURE: Erector spina plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Pharmacokinetics of Primapur and Gonal-f
Status: COMPLETED
Conditions: Area Under Curve|Pharmacokinetics|Absorption
Interventions: DRUG: Follitropin alfa (Primapur)|DRUG: Follitropin alfa (Gonal-F)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity Study in Adults of AZD1222 and rAd26-S Administered as Heterologous Prime Boost Regimen for the Prevention of Coronavirus Disease 2019 (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: AZD1222|BIOLOGICAL: rAd26-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase IIa Clinical Study of Recombinant Mycobacterium Tuberculosis Allergen ESAT6-CFP10
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: 1μg/ml ESAT6-CFP10 and tuberculin purified protein derivative|BIOLOGICAL: 5μg/ml ESAT6-CFP10 and tuberculin purified protein derivative|BIOLOGICAL: 10μg/ml ESAT6-CFP10 and tuberculin purified protein derivative|BIOLOGICAL: 20μg/ml ESAT6-CFP10 and tuberculin purified protein derivative|BIOLOGICAL: 1μg/ml ESAT6-CFP10 and placebo|BIOLOGICAL: 5μg/ml ESAT6-CFP10 and placebo|BIOLOGICAL: 10μg/ml ESAT6-CFP10 and placebo|BIOLOGICAL: 20μg/ml ESAT6-CFP10 and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury|Vestibular Neuropathy
Interventions: DEVICE: Incremental Velocity Error (IVE)|BEHAVIORAL: Traditional Vestibular Rehabilitation (VPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Hodgkin's Lymphoma|Non-Hodgkin's Disease|Acute Leukemia|Multiple Myeloma
Interventions: BIOLOGICAL: Rituximab|DRUG: Cyclosporine|DRUG: Allogenic stem cell transplant (ASCT)|DRUG: Conditioning Chemotherapy|DRUG: TMS|DRUG: FLAG|DRUG: EPOCH-F|BIOLOGICAL: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RA101495 in Subjects With Generalized Myasthenia Gravis
Status: COMPLETED
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: zilucoplan (RA101495)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Minimal Residual Disease
Interventions: DRUG: Fludarabine Phosphate|DRUG: Cyclophosphamide|DRUG: Cetuximab|DRUG: TROP2-CAR-NK Cells|DRUG: Rimiducid (AP1903)|PROCEDURE: Lymphodepleting Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)
Status: COMPLETED
Conditions: Leukemia, Acute Lymphoblastic|Myeloid Leukemia, Acute|Biphenotypic Acute Leukemia|Lymphoblastic Lymphoma|Myelodysplastic Syndromes|Myeloproliferative Neoplasm
Interventions: DRUG: Fludarabine|DRUG: Bendamustine Hydrochloride|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus 5Mg Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib in Patients With Advanced Gastric Cancer and Treated With FOLFIRI
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: DRUG: Sunitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of CYP3A4 Inhibition on the Single Dose Pharmacokinetics of ASTX660 and the Effect of a Single Dose of ASTX660 on the Pharmacokinetics of the CYP3A4 Substrate Midazolam
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: ASTX660|DRUG: Midazolam|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study With Afuresertib and Paclitaxel in Platinum Resistant Ovarian
Status: COMPLETED
Conditions: Platinum-resistant Ovarian Cancer
Interventions: DRUG: Paclitaxel|DRUG: Afuresertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Thermic Devices in the Treatment of Meibomian Gland Dysfunction
Status: RECRUITING
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Mibo Thermoflo|OTHER: Warm compresses and eyelid massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation
Status: WITHDRAWN
Conditions: Stroke
Interventions: DRUG: Placebo|DRUG: Levodopa / Carbidopa|DEVICE: Armeo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VITamine D Supplementation in RenAL Transplant Recipients - VITALE
Status: COMPLETED
Conditions: Renal Transplant Candidate for Right Kidney
Interventions: DRUG: Cholecalciferol 100 000 UI|DRUG: Cholecalciferol 12 000 UI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Partners in Caring for Anxious Youth
Status: RECRUITING
Conditions: Anxiety, Separation|Anxiety, Generalized|Anxiety, Social
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DRUG: Combination therapy (COMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia
Status: COMPLETED
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Hypoxemia
Interventions: DRUG: Inhaled Low molecular weight heparin|DRUG: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Follow-up of Treatment With Remestemcel-L in Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute GVHD
Status: COMPLETED
Conditions: Grade B Acute Graft Versus Host Disease|Grade C Acute Graft Versus Host Disease|Grade D Acute Graft Versus Host Disease
Interventions: BIOLOGICAL: Remestemcel-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metabolic Effect of an Innovative Chitosan Formulation
Status: UNKNOWN
Conditions: Hypercholesterolemia|Overweight and Obesity
Interventions: DEVICE: Medical Device (Kaptufat®)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Falls Reduction of a Multimodal Intervention in Frail and Pre-frail Elderly Community-dwelling People
Status: UNKNOWN
Conditions: Accidental Falls
Interventions: OTHER: Multicomponent physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma Histology
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell|Carcinoma, Adenosquamous|Carcinoma, Large Cell|Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: CP-751,871 (Figitumumab)|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analysis of Risk Factors for Recurrent Pregnancy Loss and Prediction of Pregnancy Loss Risk
Status: NOT_YET_RECRUITING
Conditions: Recurrent Miscarriage
Interventions: DIAGNOSTIC_TEST: Hematologic features|DIAGNOSTIC_TEST: Ultrasound indices of uterine artery blood flow|OTHER: Demographic characteristics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study of Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells, for the Treatment of Pediatric Participants Who Have Failed to Respond to Steroid Treatment for Acute Graft-Versus-Host Disease (aGVHD)
Status: COMPLETED
Conditions: Grade B aGVHD|Grade C aGVHD|Grade D aGVHD
Interventions: DRUG: remestemcel-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRSOPA-Drills to Improve Mask Ventilation in the Delivery Room
Status: COMPLETED
Conditions: Apnea|Bradycardia
Interventions: PROCEDURE: Control group|PROCEDURE: MR SOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cementless Alumina-Alumina Total Hip and Hybrid
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Avascular Necrosis
Interventions: DEVICE: Alumina/Alumina|DEVICE: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Cardiac Death|Hemorrhage|Cerebrovascular Accident|Myocardial Infarction
Interventions: DEVICE: BES (biodegradable polymer biolimus-eluting stent)|DRUG: Prasugel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Squamous Cell Carcinoma|Carcinoma of Head/Neck
Interventions: DRUG: Taxotere|DRUG: Cisplatin|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: G-CSF|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Clinical Study on Shuganjieyu Capsule Combined With Fluoxetine in the Treatment of Depression
Status: UNKNOWN
Conditions: Outpatients / Inpatients With Depression
Interventions: DRUG: Shuganjieyu capsule|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Incremental Doses of a Sugar Replacer Blend on Gastrointestinal Tolerance in Chocolate
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Tolerance|Healthy Population
Interventions: OTHER: Milk Chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Resilience Psychoeducation Program Based on Positive Psychotherapy on Nurses
Status: COMPLETED
Conditions: Psychological Stress
Interventions: BEHAVIORAL: Participants in the 8-week program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing Radiochemotherapy With Folfox 4 Regimen or 5FU-Cisplatin in Patients With Inoperable Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DRUG: FOLFOX 4|DRUG: 5-FU / Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Efficacy and Safety of REGPARA Drug in Dialysis Patients Have High Blood Levels of Parathyroid
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary
Interventions: DRUG: calcium sensing receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Cost Effectiveness of MYCOPD in Patients With Mild and Moderate Newly Diagnosed COPD
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: myCOPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Education Provided With Pecha Kucha Method on Cancer Patients Receiving Chemotherapy on Symptom Management and Quality of Life
Status: RECRUITING
Conditions: Symptom Management|Life Quality
Interventions: BEHAVIORAL: symptom management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Optimal Route of Fecal Microbiota Transplantation for Irritable Bowel Syndrome
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome|Microbial Substitution
Interventions: OTHER: Fecal microbiota transplant or plasebo through endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT