pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Peripheral Nerve Blockade|BEHAVIORAL: 10 meter walk test on post-operative day 1|OTHER: In person and over the phone questionnaire|DEVICE: Force transduction of quadriceps strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Hepatosplenic T-cell Lymphoma|Peripheral T-cell Lymphoma
Interventions: DRUG: prednisone|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: Vincristine|DRUG: pralatrexate|OTHER: laboratory biomarker analysis|GENETIC: comparative genomic hybridization|GENETIC: gene expression analysis|GENETIC: nucleic acid sequencing|GENETIC: mutation analysis|OTHER: immunohistochemistry staining method|GENETIC: microarray analysis|GENETIC: RNA analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dapagliflozin to Prevent the Incidence of Contrast Induced Nephropathy After Heart Catheterization and Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Left Cardiac Catheterization|Percutaneous Coronary Intervention|Acute Kidney Injury|Sodium-glucose Co-transporter 2 Inhibitors
Interventions: DRUG: Dapagliflozin 5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Napping in Pregnant Women With Sleep Disturbances on Offspring Neurodevelopment
Status: NOT_YET_RECRUITING
Conditions: Sleep
Interventions: BEHAVIORAL: lifestyle recommendations to nap regularly|OTHER: No recommendations to nap regularly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-Guided ONB for Transurethral Procedures - Interadductor Approach
Status: UNKNOWN
Conditions: Urinary Bladder Neoplasms|Transurethral Resection|Nerve Block
Interventions: DEVICE: Ultrasound|DRUG: lidocaine 2%|DRUG: 0.9% Natrium Chloratum with a 2nd generation cephalosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia in Remission|Hematopoietic Cell Transplantation Recipient|JAK2 Gene Mutation|Loss of Chromosome 17p|Mantle Cell Lymphoma|Minimal Residual Disease|Myelodysplastic Syndrome|Non-Hodgkin Lymphoma|Plasma Cell Myeloma|RAS Family Gene Mutation|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Hematologic Malignancy|Recurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Therapy-Related Acute Myeloid Leukemia|Therapy-Related Myelodysplastic Syndrome|TP53 Gene Mutation
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Irradiated Allogeneic Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: AS-101
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design
Status: RECRUITING
Conditions: Periprosthetic Osteolysis
Interventions: DIAGNOSTIC_TEST: dual energy x-ray absorptiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2, Dose-finding, Cross-over Study to Evaluate the Effect of a NES/E2 Transdermal Gel Delivery on Ovulation Suppression in Normal Ovulating Women
Status: COMPLETED
Conditions: Ovulation
Interventions: DRUG: NES/E2 gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|OTHER: Gallium Ga 68 Gozetotide|DRUG: Lutetium Lu 177 Vipivotide Tetraxetan|PROCEDURE: Positron Emission Tomography|PROCEDURE: Single Photon Emission Computed Tomography|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)|Cancer of Pancreas|Pancreatic Cancer, Adult|Pancreas Adenocarcinoma|Pancreatic Neoplasms|Pancreatic Cancer Non-resectable|Pancreatic Cancer Resectable
Interventions: DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Irinotecan Hydrochloride|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Software Treatment for Actively Reducing Severity of ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DEVICE: AKL-T01|DEVICE: AKL-T09
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Metoprolol as add-on Treatment to Standard of Care in Preventing Cardiomyopathy in Patients With DMD
Status: RECRUITING
Conditions: Muscular Dystrophy, Duchenne
Interventions: DRUG: Metoprolol Succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy
Status: TERMINATED
Conditions: Breast Cancer|Cancer
Interventions: DRUG: Venetoclax|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
Status: COMPLETED
Conditions: Cobalamin Deficiency
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Cyanocobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Maximal Repair Versus Bridging Reconstruction With BioBrace®
Status: RECRUITING
Conditions: Rotator Cuff Tears|Bioinductive Implant
Interventions: PROCEDURE: Bridging Reconstruction using BioBrace|PROCEDURE: Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness and Safety of Paliperidone Extended Release in Patients With Schizoaffective Disorder.
Status: COMPLETED
Conditions: Schizoaffective Disorder|Psychotic Disorder
Interventions: DRUG: Paliperidone ER|DRUG: Paliperidone ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Human Technology for Patients With Chronic Pain
Status: COMPLETED
Conditions: Chronic Musculoskeletal Pain
Interventions: BEHAVIORAL: Emotional Disclosure and Brain Education|BEHAVIORAL: Emotional Disclosure Only|BEHAVIORAL: Pain Information Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Assess the Pharmacokinetic Characteristics of Lodivixx Tab. 5/160mg in Healthy Male Subjects (N=27)
Status: COMPLETED
Conditions: Healthy Male Subjects
Interventions: DRUG: Exforge tab. 10/160mg|DRUG: Lodivixx tab. 5/160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dermotaxis v/s Loop Suture Technique for Closure of Fasciotomy Wounds : a Study of 50 Cases
Status: COMPLETED
Conditions: Inexpensive Closure of Fasciotomy Incisions Without the Need for Skin Grafting
Interventions: PROCEDURE: dermotaxis|PROCEDURE: loop suture technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Narrow Band Imaging Versus White Light for Colonoscopy Serrate Lesions Detection
Status: UNKNOWN
Conditions: Colon Cancer|Colon Sessile Serrated Adenoma/Polyp
Interventions: DEVICE: narrow band imaging withdrawal|DEVICE: white light withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Four Different Dosing Regimens of Cross-Linked Polyelectrolyte (CLP) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cross-Linked Polyelectrolyte (CLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ivabradine in Cirrhotic Cardiomyopathy
Status: RECRUITING
Conditions: Cirrhotic Cardiomyopathy|Left Ventricular Dysfunction|Cirrhosis, Liver|Portal Hypertension
Interventions: DRUG: Betablocker + ivabradine|DRUG: Betablocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracerebral Transplantation of Autologous MSC Combined With Scaffold Product for Chronic Intracerebral Hemorrhage
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: HUFF-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male Volunteers
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Fimasartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Erlotinib in Treating Patients With Liver Cancer That Cannot be Surgically Removed
Status: TERMINATED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer
Interventions: DRUG: erlotinib hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Loco-regional Adjuvant Radiation Therapy of Breast Cancer Combined With a Simultaneous Integrated Boost
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphedema|Fibrosis
Interventions: RADIATION: Loco-regional RT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Provide Continued Treatment for Patients With Hematologic Malignancies Previously Enrolled in Studies With Tafasitamab
Status: RECRUITING
Conditions: Hematologic Malignancies
Interventions: DRUG: Tafasitamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Index Cholecystectomy Versus Scheduled Cholecystectomy in Biliary Pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: PROCEDURE: Index cholecystectomy|PROCEDURE: Scheduled cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flexibility, Efficacy, and Safety of a Foldable Capsular Vitreous Body in the Treatment of Severe Retinal Detachment
Status: UNKNOWN
Conditions: Retinal Detachment
Interventions: DEVICE: foldable capsular vitreous body(FCVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke
Status: RECRUITING
Conditions: Stroke, Acute Ischemic
Interventions: DRUG: Tirofiban|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Perioperative Pain
Interventions: DRUG: Bupivacaine|DRUG: isotonic saline|DRUG: Bupivacaine + morphine|DRUG: Bupivacaine + morphine + ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK-0954A|DRUG: MK-954H|DRUG: Placebo to MK-0954A|DRUG: Placebo to MK-954H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Farinelli's Breathing Exercise in COPD Patients
Status: COMPLETED
Conditions: COPD Patients
Interventions: OTHER: Farinelli's Breathing Exercise|OTHER: Diaphragmatic Breathing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Conventional AF Ablation with PVI|PROCEDURE: FIRM-guided ablation plus PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Subdural EEG-electrode And Subdural hEmatoma (DISEASE)
Status: UNKNOWN
Conditions: Seizures|Subdural Hematoma
Interventions: DEVICE: invasive subdural grid electrode|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutrigenomics, PUFA, Iron and Cognition Amongst Under-two-year-old Indonesian Children
Status: UNKNOWN
Conditions: Cognitive Ability, General
Interventions: DIETARY_SUPPLEMENT: DHA/EPA and iron supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Feasibility of Slow-paced Respiration Therapy for Treatment of a Symptom Cluster in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Slow-paced respiration therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Plus Gemcitabine in Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Regorafenib|DRUG: Gemcitabine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Olfactory Training on the Brain Function in T2DM Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Mild Cognitive Impairment
Interventions: OTHER: Olfactory Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based A-CRA for Young Adults With Problematic Alcohol Use
Status: UNKNOWN
Conditions: Alcohol Abuse|Binge Drinking|Alcohol Use Disorder
Interventions: BEHAVIORAL: Internet-delivered Adolescent Community Reinforcement Approach (I-A-CRA)|BEHAVIORAL: Psychoeducation, information on use of alcohol and its effects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831
Status: UNKNOWN
Conditions: Covid19|Corona Virus Infection|Severe Acute Respiratory Syndrome|Severe Acute Respiratory Infection|Severe Acute Respiratory Syndrome (SARS) Pneumonia|Severe Acute Respiratory Syndrome of Upper Respiratory Tract|Neurodegeneration|Neuroinflammatory Response
Interventions: DRUG: Drug: NA-831 - 0.10 mg/kg|DRUG: Placebo- 0.10 mg/kg|DRUG: Drug: NA-831 - 0.20 mg/kg|DRUG: Placebo- 0.20 mg/kg|DRUG: Drug: GS-5734 - 1.00 mg/kg|DRUG: Placebo- 1.00 mg/kg|DRUG: Drug: GS-5734 - 2.00 mg/kg|DRUG: Placebo- 2.00 mg/kg|COMBINATION_PRODUCT: Drugs: NA-831 (0.10 mg/kg) plus GS-5734 (1.00 mg/kg)|COMBINATION_PRODUCT: Placebo 0.10 mg + 1.00 mg/kg|COMBINATION_PRODUCT: Drugs: NA-831 (0.20 mg/kg) plus GS-5734 (2.00 mg/kg)|COMBINATION_PRODUCT: Placebo 0.20 mg + 2.00 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Care for Heart Failure - Randomized Clinical Trial (RCT) (Pilot Phase)
Status: RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Virtual HF Care|OTHER: Routine HF Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Preoperative Warming of Patients on Postoperative Hypothermia and Shivering
Status: COMPLETED
Conditions: Hypothermia
Interventions: PROCEDURE: duration of preoperative active warming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial Comparing Tack Versus Histoacryl Mesh Fixation After Endoscopic TEP(Total Extraperitoneal) Repair for Bilateral Inguinal Hernia
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Tack fixation of mesh|PROCEDURE: Synthetic glue fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
Status: UNKNOWN
Conditions: Malocclusion
Interventions: DEVICE: Invisalign (7 day)|DEVICE: Invisalign (5 day)|DEVICE: OrthoPulse|DEVICE: Invisalign (3.5 day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Fixed-dose Combination Tablets Containing Estradiol and Nomegestrol Acetate
Status: WITHDRAWN
Conditions: Bioequivalence
Interventions: DRUG: Estradiol 1.5 mg/nomegestrol acetate 2.5 mg (Reference Product)|DRUG: Estradiol 1.5 mg/nomegestrol acetate 2.5 mg (Test Product)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Polyunsaturated Fatty Acids for Adjunctive Treatment of Refractory Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Fish oil (Super Omega-3, 4 caps/d) vs. placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Shoulder Joint Disorder|Ambulatory Surgical Procedures|Brachial Plexus Block
Interventions: DRUG: Dexamethasone|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)
Status: RECRUITING
Conditions: Squamous Cell Carcinoma|the Nasal Cavity|Paranasal Sinuses
Interventions: DRUG: Pembrolizumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders
Status: TERMINATED
Conditions: DeQuervains Tenosynovitis|Lateral Epicondylitis|Tennis Elbow|Trigger Finger|Tenosynovitis|Inflammatory Disease
Interventions: DRUG: Ketorolac|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Refractory/Relapsed Non-Hodgkin Lymphoma With TriCAR-T_CD19
Status: UNKNOWN
Conditions: Non-hodgkin Lymphoma,B Cell
Interventions: BIOLOGICAL: TriCAR-T-CD19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Roll-over Study to Allow Access to Certinib (LDK378) for Patients Who Are on Ceritinib Treatment in a Novartis-sponsored Study
Status: ACTIVE_NOT_RECRUITING
Conditions: ALK Positive Malignancies
Interventions: DRUG: ceritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMP321 (Eftilagimod Alpha) as Adjunctive to a Standard Chemotherapy Paclitaxel Metastatic Breast Carcinoma
Status: COMPLETED
Conditions: Adenocarcinoma Breast Stage IV
Interventions: BIOLOGICAL: IMP321 (eftilagimod alpha)|DRUG: Placebo|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
Status: RECRUITING
Conditions: Erectile Dysfunction
Interventions: DEVICE: VERTICA Active device|DEVICE: VERTICA Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Improvement Following Tongue-tie and Lip-tie Release
Status: COMPLETED
Conditions: Ankyloglossia|Breastfeeding
Interventions: PROCEDURE: Lingual Frenotomy and/or maxillary labial frenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of IFN α2b for Melanoma Patients
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: IFNα2b|DRUG: IFNα2b|DRUG: PEG- IFNα2b|DRUG: PEG- IFNα2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Methods of Colonic Transendoscopic Enteral Tubing
Status: UNKNOWN
Conditions: Colonic Transendoscopic Enteral Tubing
Interventions: PROCEDURE: colonic transendoscopic enteral tubing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Multicentre Trial to Determine the Efficacy and Safety of Milnacipran in the Treatment of Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: DRUG: milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of XOMA 052 on Insulin Production in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1
Interventions: DRUG: XOMA 052|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Superoxide Dismutase (GLISODin) to Decrease Melasma Severity.
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: Glisodin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: One Anastomosis Gastric Bypass With Excluded Stomach Fundoplication: FundoRing vs Nissen vs OAGB Without Fundoplication
Status: COMPLETED
Conditions: Obesity|GERD
Interventions: PROCEDURE: laparoscopic one anastomosis gastric bypass with excluded stomach fundoplication: FundoRingOAGB and suture cruroplasty|PROCEDURE: laparoscopic one anastomosis gastric bypass with excluded stomach Nissen fundoplication and suture cruroplasty|PROCEDURE: Standard laparoscopic one anastomosis gastric bypass with cruroplasty. Not used fundoplication.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Evaluate a Systematized Communication Model for Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer Stage IV|Breast Cancer Metastatic|Communication
Interventions: OTHER: Communication model
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study To Assess Safety, Tolerability And PK Of ATB-346 In Healthy Subjects
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: ATB-346|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Optimal Transition Program
Status: UNKNOWN
Conditions: ESRD|Hemodialysis
Interventions: OTHER: Analysis using descriptive statistics of patient clinical outcomes.|OTHER: Surveys with participants using validated survey tools.|OTHER: Evaluation of the program process including time, costs, referral rates, admission to the program and length of stay.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HYPNONAG : Therapeutic Communication Versus Traditional Method for Naso-gastric Intubation in Haematology
Status: RECRUITING
Conditions: Aplasia|Chemotherapy Effect
Interventions: OTHER: Standard intubation|OTHER: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines)
Status: UNKNOWN
Conditions: Small Intestinal Carcinoid Tumors
Interventions: GENETIC: Research of constitutional genetic alterations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impacts of Surgical Visibility Through Deep Neuromuscular Blockade on Intraocular Pressure in Patients Undergoing Robot-Assisted Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Robot-Assisted Laparoscopic Radical Prostatectomy
Interventions: PROCEDURE: deep neuromuscular blockade|PROCEDURE: moderate neuromuscular blockade|DRUG: Rocuronium|DRUG: Sugammadex|DRUG: Atracurium|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Value of Circulating Tumour DNA in Follow-up of Patients With an Advanced Gastroenteropancreatic or Lung Neuroendocrine Tumour Under Everolimus +- SSA Treatment
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: OTHER: Liquid biopsies|OTHER: Scans (CT, gallium-68 DOTATE/TOC/NOC PET-CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Effects of Diazepam and Lorazepam
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Diazepam|DRUG: Lorazepam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
Status: RECRUITING
Conditions: Influenza|Community-acquired Pneumonia|Cardiovascular Events
Interventions: BIOLOGICAL: Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4)|BIOLOGICAL: High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Steroids and Azathioprine in Advanced IgAN
Status: COMPLETED
Conditions: IgA Nephropathy|Chronic Kidney Disease
Interventions: DRUG: methylprednisolone|DRUG: azathioprine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Alemtuzumab in Auotoimmune Cytopenias
Status: TERMINATED
Conditions: Autoimmune Cytopenias
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panobinostat/Velcade in Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib (Velcade)|DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SteamOne - Prospective Registry Database for Rezum Water Vapor Therapy of the Prostate
Status: RECRUITING
Conditions: Benign Prostate Obstruction (BPO)
Interventions: OTHER: Collection and evaluation of clinical (CROMs) and patient-reported outcomes (PROMs)|OTHER: Analysis of uroflowmetry data by Kesem Health iUFlow medical uroflowmetry device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regulation of Cortisol Metabolism and Fat Patterning
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Menopausal Syndrome
Interventions: DRUG: Placebo injection|DRUG: Depo Lupron/Aromatase inhibitor|DRUG: Depo Lupron/placebo|DRUG: placebo|DRUG: Estrogen cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intervention in Chronic Pediatric Patients and Their Families.
Status: COMPLETED
Conditions: Type 1 Diabetes|Allergic Rhinitis|Allergic Asthma|Asthma|Short Stature|Food Allergy|Atopic Dermatitis|Rhinoconjunctivitis|Cystic Fibrosis|Primary Ciliary Dyskinesia|Pulmonary Disease
Interventions: OTHER: Ten Vida (10Vida)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: InterStim Therapy Programming Study
Status: COMPLETED
Conditions: Urgency Frequency|Urinary Urge Incontinence
Interventions: DEVICE: InterStim Therapy at rate 5.2 Hz|DEVICE: InterStim Therapy at rate 14 Hz|DEVICE: InterStim Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: A Study Using Intravenous Paxceed™ to Treat Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Micellar Paclitaxel for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Web-Based Emotion Regulation Training in a Transdiagnostic Sample
Status: RECRUITING
Conditions: Emotion Regulation|Anxiety Disorders|Depression|Eating Disorders|Borderline Personality Disorder
Interventions: BEHAVIORAL: Heidelberg Emotion Regulation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lowlands Saves Lives: A Randomized Trial Comparing CPR-quality Between Face-to-face vs. Lifesaver VR Training
Status: COMPLETED
Conditions: Cardiac Arrest|Cardiopulmonary Arrest|Out-Of-Hospital Cardiac Arrest
Interventions: OTHER: Lifesaver virtual reality training|OTHER: Face-to-face training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Research and Development of a New Technology for Detection of Abnormal Excretion of Intestinal Uric Acid Involved in the Incidence of Gout
Status: UNKNOWN
Conditions: Gout|Hyperuricemia|Gut Microbiota|Uric Acid|Genetic Loci|Single Nucleotide Polymorphism|Feces
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial
Status: COMPLETED
Conditions: Aneurysm
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of DisCoVisc Ophthalmic Viscosurgical Device (OVD) on Intraoperative Aberrometry Readings
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: BSS|DEVICE: DiscoVisc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)
Status: COMPLETED
Conditions: Stage IV or Recurrent Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Nivolumab|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibitory rTMS in Dystonic Wilson Patients
Status: COMPLETED
Conditions: Wilson Disease|Movement Disorders|Repetitive Transcranial Magnetic Stimulation
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|OTHER: pre and post-rTMS electroencephalogram|OTHER: WCRS|OTHER: handwriting scale DPRE|OTHER: visual analog scale of discomfort writing and parameters collected on touchpad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: cetuximab|DRUG: 5-FU|DRUG: irinotecan|DRUG: leucovorin|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of NicVAX® Co-administered With Varenicline (Champix®)
Status: COMPLETED
Conditions: Smoking Behavior|Smoking Lapse Behavior|Smoking Relapse Behavior
Interventions: BIOLOGICAL: NicVAX vaccine|BIOLOGICAL: Placebo|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Ketosis After Intake of Coconut Oil and Caprylic Acid-With and Without Glucose-After a 12-hour Fast
Status: COMPLETED
Conditions: Aged
Interventions: OTHER: Coconut oil|DIETARY_SUPPLEMENT: Caprylic acid|OTHER: Sunflower oil|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Therapeutic Hepatitis B Adenovirus Injection (T101) in Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Hepatitis B Virus (HBV)
Interventions: BIOLOGICAL: T101 Group|BIOLOGICAL: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML
Status: ACTIVE_NOT_RECRUITING
Conditions: AML With Monocytic Differentiation|CMML
Interventions: BIOLOGICAL: IO-202|BIOLOGICAL: IO-202 and Azacitidine|BIOLOGICAL: IO-202 and Azacitidine + Venetoclax|BIOLOGICAL: IO-202 and Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population
Status: COMPLETED
Conditions: Peptic Ulcers
Interventions: DRUG: Celecoxib|DRUG: Naproxen|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) - Outcome Study of Cryotherapy for Retinopathy of Prematurity
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: PROCEDURE: Trans-scleral Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Myocardial Strain Analysis in Anaesthetized Coronary Artery Disease Patients During Hyperoxia and Normoxaemia
Status: COMPLETED
Conditions: Coronary Artery Disease|Anesthesia
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intervention to Reduce Fear of Hypoglycemia and Optimize Type 1 Diabetes Outcomes
Status: COMPLETED
Conditions: Type1diabetes|Fear of Hypoglycemia
Interventions: BEHAVIORAL: Fear of Hypoglycemia|OTHER: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glossopharyngeal Nerve Block for Post -Tonsillectomy Pain Relief
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: bilateral ultrasound guided GPN block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors
Status: NOT_YET_RECRUITING
Conditions: Suicide|Suicide, Attempted
Interventions: DIAGNOSTIC_TEST: Clinician Decision Support Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Noninvasive High Frequency Oscillatory Ventilation on Improving CO2 Clearance in COPD Patients
Status: NOT_YET_RECRUITING
Conditions: COPD Exacerbation|Non-invasive Ventilation
Interventions: DEVICE: Non-invasive high-frequency oscillatory|DEVICE: Noninvasive Bilevel Positive Pressure Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etoricoxibe - Preemptive and Postoperative Analgesia for Abdominal and Thoracic Surgery
Status: TERMINATED
Conditions: Pain|Abdominal Surgery|Thoracic Surgery
Interventions: DRUG: Etoricoxibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ingesting or Rinsing Sucrose and Sucralose on Self-control, Cognitive Performance, and Blood Glucose
Status: COMPLETED
Conditions: Self-control|Cognitive Performance|Blood Glucose Response
Interventions: DIETARY_SUPPLEMENT: Ingestion of solution|DIETARY_SUPPLEMENT: Rinising of solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
Status: RECRUITING
Conditions: Cervical Spine Fusion
Interventions: DRUG: Bupivacain|DRUG: Dexamethasone|DRUG: Epinephrine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PF-07104091 as a Single Agent and in Combination Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Small Cell Lung Cancer|Ovarian Cancer|Breast Cancer
Interventions: DRUG: PF-07104091 monotherapy dose escalation|DRUG: PF-07104091 + palbociclib + fulvestrant|DRUG: PF-07104091 + palbociclib + letrozole|DRUG: PF-07104091 monotherapy dose expansion (ovarian)|DRUG: PF-07104091 monotherapy dose expansion (SCLC)|DRUG: PF-07104091 + Fulvestrant (post CDK4/6)|DRUG: PF-0704091 + Fulvestrant (post CDK4/6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing EMDR and CBT for Treatment of Resistant Depression
Status: RECRUITING
Conditions: Eye Movement Desensitization and Reprocessing|Cognitive Behavioral Therapy|Neurobiological Processing|Depression|Functional Magnetic Resonance Imaging|High Definition Electroencefalography|Heart Rate Variability
Interventions: BEHAVIORAL: EMDR|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GLP1 receptor agonist|DRUG: basal insulin|DRUG: SGLT2 inhibitor|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Coaching as a Tool for Improving Medication Adherence in Adult Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Health Coaching|OTHER: Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Determine the Frequency of Variants in the GBA/PSAP Genes in Patients With MM or MGUS
Status: NOT_YET_RECRUITING
Conditions: Monoclonal Gammopathy of Undetermined Significance|Myeloma Multiple
Interventions: BIOLOGICAL: Evaluation of the presence and number of mutated alleles of the GBA/PSAP genes in patients with MM or MGUS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Correlation Between the Pulmonary Function Parameters and the Circulatory Parameters (PSV, EDV, RI) of Retrobulbar Blood Vessels (CRA, PCA, and OA) in 48 T2DM Patients Did Not Combinate With DR
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: spirometer;Intraocular pressure;Color doppler imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunity Against SARS-CoV2 in Children and Their Parents / COVID-19
Status: COMPLETED
Conditions: COVID-19 Infection
Interventions: BIOLOGICAL: serology test|BIOLOGICAL: nasopharyngeal swab|BIOLOGICAL: rectal swab|BIOLOGICAL: saliva sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of L-cysteine in Prevention of Headache Attacks in Migraine Patients
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Acetium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Pilates Training in Parkinson Patients
Status: COMPLETED
Conditions: Parkinson Disease|Pilates|Core Stability|Balance|Quality of Life
Interventions: OTHER: Pilates Training|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Cisplatin and Bevacizumab in ER-, PR-, HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cisplatin|DRUG: bevacizumab|DRUG: doxorubicin|DRUG: cyclophosphamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of Pacifier Use in Preterm During Orogastric Tube Feeding
Status: UNKNOWN
Conditions: Premature|Pacifiers|Tube Feeding|Neonatal Nursing
Interventions: PROCEDURE: Pacifier|PROCEDURE: Breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE