pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Exploratory Tumor Biopsy-driven Study to Understand the Relationship Between Biomarkers and Clinical Response in Melanoma Patients Receiving REGN2810 (Anti-PD-1)
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: REGN2810
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotypic Characterization Tumor-infiltrating Lymphocytes at Diagnosis and After Chemotherapy in Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer Stage IIIC|Fallopian Tube Cancer Stage IIIC|Fallopian Tube Cancer Stage IV|Ovarian Cancer Stage IV
Interventions: PROCEDURE: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Exercise Intervention in Patients With Spondylolisthesis Related LBP
Status: COMPLETED
Conditions: Low Back Pain|Spondylolisthesis
Interventions: PROCEDURE: Exercise intervention|PROCEDURE: Exercise and e-stim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RYGB AL 150cm BPL 100cm vs RYGB AL 100cc BPL 150cm
Status: UNKNOWN
Conditions: Weight Loss
Interventions: PROCEDURE: AL 150 BPL100|PROCEDURE: AL 100 BPL 150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability and Pharmacokinetics of EYP001a in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: EYP001a|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect Of Whole-Body Vibration And Walk in Osteoporosis/Osteopenia
Status: COMPLETED
Conditions: Osteoporosis
Interventions: OTHER: Training in the vibrating platform|OTHER: Walk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Multiple Myeloma|Non-Hodgkin Lymphoma|Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Chronic Myeloid Leukemia
Interventions: DRUG: OPB-51602
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Electronic Information Kiosks Enhance Patient Accrual for Cancer Clinical Trials? A Pilot and Feasibility Study
Status: COMPLETED
Conditions: Malignant Neoplasm
Interventions: OTHER: Clinical Trial Kiosk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexamethasone Iontophoretic Patch for the Treatment of Pain Associated With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|(Tennis Elbow)
Interventions: DRUG: Dexamethasone Iontophoretic Patch (low dose)|DRUG: Dexamethasone Iontophoretic Patch (high dose)|DRUG: Dexamethasone Passive Patch|DRUG: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electric Nerve Stimulation (TENS) in Children With Enuresis
Status: COMPLETED
Conditions: Enuresis|Nocturnal Enuresis|Urinary Incontinence
Interventions: DEVICE: Transcutaneous Electric Nerve Stimulation (TENS) - active|DEVICE: Transcutaneous Electric Nerve Stimulation (TENS) - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature
Status: COMPLETED
Conditions: Major Surgery Under General Anesthesia
Interventions: OTHER: Ambient Temperature 19°C|OTHER: Ambient Temperature 21°C|OTHER: Ambient Temperature 23°C|DEVICE: Forced-air cover (Bair hugger 63500, 3M)|OTHER: Passive insulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Exenatide|DRUG: Glargine|DRUG: Rapid-acting insulin analogs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Pattern During Neurally Adjusted Ventilator Assist (NAVA) in Preterm Infants
Status: COMPLETED
Conditions: Respiratory Distress Syndrome In Premature Infants|Preterm Infants
Interventions: DEVICE: Increasing and decreasing NAVA levels with 10-min intervals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer|Estrogen-receptor Positive Breast Cancer|Cancer, Breast|Breast Cancer Female|Breast Adenocarcinoma|Estrogen Receptor Positive Tumor|ER Positive
Interventions: DRUG: H3B-6545
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MDX-010 in Treating Patients With Recurrent or Refractory Lymphoma
Status: TERMINATED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|B-cell Chronic Lymphocytic Leukemia|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: BIOLOGICAL: ipilimumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Radiation to Prevent Complications of Back Surgery
Status: COMPLETED
Conditions: Failed Back Surgery Syndrome|Postlaminectomy Syndrome|Postdiscectomy Epidural Fibrosis
Interventions: PROCEDURE: Lumbar nerve root decompression|PROCEDURE: Preoperative low-dose external beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Mamma HiToP Study
Status: RECRUITING
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: HiToP 191 PNP|DEVICE: Placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venous Thromboembolism Prophylaxis After Gynecological Pelvic Cancer Surgery With Rivaroxaban vs Enoxaparin
Status: UNKNOWN
Conditions: Cancer|Rivaroxaban|Venous Thromboembolism|Thromboprophylaxis
Interventions: DRUG: Rivaroxaban|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Efficacy and Safety of Amicomed®, for the Management of Essential Hypertension
Status: NOT_YET_RECRUITING
Conditions: Essential Hypertension|Primary Hypertension
Interventions: DEVICE: Amicomed®|DEVICE: Digital Placebo|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BF2.649 in Patients With OSA and Treated by CPAP But Still Complaining of EDS
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Excessive Daytime Sleepiness
Interventions: DRUG: BF2.649|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ChulaCov19 Vaccine in Healthy Adults
Status: COMPLETED
Conditions: COVID-19 Vaccine|Safety Issues
Interventions: BIOLOGICAL: ChulaCov19 vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacodynamic Study Comparing the Effects of Two Different Forms of Omeprazole (P07812) (COMPLETED)
Status: COMPLETED
Conditions: Intragastric Acidity
Interventions: DRUG: Zegerid|DRUG: Prilosec OTC™ Tablets|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET)
Status: RECRUITING
Conditions: Essential Tremor
Interventions: DRUG: 60 mg ulixacaltamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Outcomes of Surgical Management of Deep Endometriosis Infiltrating the Rectum
Status: UNKNOWN
Conditions: Endometriosis, Rectum
Interventions: PROCEDURE: Rectal/colorectal segmental resection|PROCEDURE: Rectal nodule excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effect Of Inhaling A Single Dose Of GW642444M In COPD Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444M|DRUG: GW642444H|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intramuscular Ketamine Versus Aripiprazole and Escitalopram in the Treatment of Resistant Depression
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: DRUG: Ketamine|DIAGNOSTIC_TEST: Cognition|OTHER: Suicide risk|OTHER: Depression thoughts|OTHER: Quality of life and disability|OTHER: Clinical and epidemiological factors|DEVICE: Safety of ketamine IM|OTHER: Tolerability of ketamine IM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Health Promotion Project for Workers at National Taiwan University Hospital
Status: UNKNOWN
Conditions: Abdominal Obesity Metabolic Syndrome|Subjects With Poor Fitness Status
Interventions: OTHER: Intensive exercise|OTHER: Home exercise|OTHER: Control group live as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of an Injectable Hyaluronic Acid-based Filler, Art Filler® Volume: Comparative Single-blind Study of the Non-inferiority Versus Juvéderm® Voluma on the Midface, Temple and Jaw-line and Non-comparative Study on the Chin. (AF3)
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Face correction with injectable fillers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Compare Between CT-P41 and US-licensed Prolia in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Women With Osteoporosis
Interventions: BIOLOGICAL: CT-P41|BIOLOGICAL: US-licensed Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Paliperidone Enantiomer Disposition With Different Formulations and the Bioavailability of Immediate- and Extended-release Paliperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: IR OROS paliperidone and ER OROS paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)
Status: RECRUITING
Conditions: Malignant Female Reproductive System Neoplasm|Malignant Solid Neoplasm|Recurrent Malignant Female Reproductive System Neoplasm|Recurrent Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|DRUG: Neratinib Maleate|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare Sequential and Quadruple Therapy for the Eradication of Helicobacter Pylori in Korea
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Pantoprazole|DRUG: Amoxicillin|DRUG: Clarithromycin|DRUG: Metronidazole|DRUG: Tetracycline|DRUG: Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Sorafenib|DRUG: Erlotinb
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vorinostat and Gefitinib in Relapsed/ or Refractory Patients With Advanced Non-small Cell Carcinoma (NSCLC)
Status: UNKNOWN
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Study treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Multiple Dose Levels of SRT2379 on Endotoxin-Induced Inflammation
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: SRT2379|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measurement of Forces Applied Using a Macintosh Direct Laryngoscope Compared to GlideScope Video Laryngoscope
Status: COMPLETED
Conditions: Moderately Difficult to Intubate
Interventions: DEVICE: Intubation with GlideScope Video Laryngoscope or Macintosh Direct Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Sleep Quality of Patients Anesthesia With Propofol or Sevoflurane Undergoing Thyroidectomy
Status: COMPLETED
Conditions: Postoperative Sleep Quality
Interventions: DRUG: propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AZT-04 for Cosmetic Use
Status: COMPLETED
Conditions: Study of Three Doses of AZT-04 for Skin Appearance
Interventions: OTHER: AZT-04
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Duloxetine for LBP
Status: RECRUITING
Conditions: Back Pain, Low
Interventions: DRUG: Naproxen|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients
Status: COMPLETED
Conditions: Neurofibromatosis 2
Interventions: DRUG: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: A-Phase: tirofiban; Z-Phase simvastatin|DRUG: Duration of Treatment: A-Phase: minimum suggested 48 hours, maximum suggested 108 hours. Z-Phase: 2 years|DRUG: Comparator: A-Phase: low molecular weight heparin, unfractionated heparin|DRUG: Duration of Treatment: A-Phase: low molecular weight heparin, 2 to 8 days; unfractionated heparin, minium suggested 48 hours, maximum 108 hours|DRUG: Duration of Treatment: Z-Phase, 2 years.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Medrol Dosepak for Outpatient Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-response Study of Paricalcitol Injection in Chronic Kidney Disease Patients Receiving Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease on Hemodialysis|Secondary Hyperparathyroidism
Interventions: DRUG: Maxacalcitol|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexamethasone on Cortisol Levels in Patients Undergoing Thyroid Surgery
Status: WITHDRAWN
Conditions: Adrenal Insufficiency
Interventions: DRUG: Dexamethasone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Vaccination of Melanoma Patients With Total or CD25-depleted Peripheral Blood Mononuclear Cell (PBMC)
Status: TERMINATED
Conditions: Melanoma
Interventions: BIOLOGICAL: PBMC re-infusion|BIOLOGICAL: CD25 depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Climacteric Symptoms With a Complex Homeopathic Remedy
Status: COMPLETED
Conditions: Menopause|Anxiety Disorders|Depression
Interventions: DRUG: ovaria comp 10 globuli 3 times per day 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Integrated Attention Program (DAIP) in People With Severe Dual Diagnosis
Status: UNKNOWN
Conditions: Diagnosis, Dual (Psychiatry)
Interventions: BEHAVIORAL: D-AIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biofeedback Gait Training on Gait Quality in Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: OTHER: Gait training with biofeedback|OTHER: Gait training without biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paracetamol UNIFLASH for Buccal Use Phase III Trial in Acute Pain Due to a Tooth Extraction
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Paracetamol Uniflash 125mg|DRUG: Panadol 500 MG Oral Tablet X1|DRUG: Panadol 500 MG Oral Tablet X2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gynaecological Follow-up of a Subset of HPV-015 (NCT00294047) Study Subjects
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: PROCEDURE: Gynaecological follow-up|BIOLOGICAL: Cervarix|BIOLOGICAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Walnut Shell Glasses Moxibustion for Dry Eye Syndrome
Status: UNKNOWN
Conditions: Dry Eye
Interventions: PROCEDURE: Walnut Shell Glasses Moxibustion|DRUG: Sodium hyaluronate eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Hepatic Steatosis on the Therapeutic Effect of Entecavir in Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis B|Hepatic Steatosis
Interventions: DRUG: entecavir|DRUG: entecavir|DRUG: essentiale + entecavir|DRUG: Vitamin E + entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics
Status: COMPLETED
Conditions: Alcohol Use Disorder|Bipolar Disorder
Interventions: DRUG: N-Acetylcysteine|DRUG: Gabapentin|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative and Efficacy Study of ACTHar Gel Alone or in Combination With Tacrolimus in Fibrillary Glomerulopathy
Status: WITHDRAWN
Conditions: Renal Disease
Interventions: DRUG: Acthar 80 UNT/ML Injectable Solution|DRUG: Oral Tab Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DUMAS: Neo-Adjuvant Immunotherapy for Pancoast Tumors
Status: RECRUITING
Conditions: NSCLC|Pancoast Tumor
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ia/Ib Open Label，Clinical Study Evaluating the Safety, Tolerability and Preliminary Efficacy of AK127 in Combination With AK104 in Patients With Advanced Malignant Tumors
Status: RECRUITING
Conditions: Advanced Malignant Tumors
Interventions: DRUG: AK127 Q3W IV infusion ,AK104 10mg/kg Q3W IV infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regadenoson Real Time Perfusion Imaging Trial-Optison
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Perfusion Abnormalities
Interventions: DRUG: Regadenoson; Optison
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Laser Therapy in Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DEVICE: high-intensity laser therapy & exercises|DEVICE: Shame laser & exercises|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4451
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: AZD4451|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Moringa Powder Acceptability Trial Among Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Consumption|Acceptability|Side Effect
Interventions: OTHER: Moringa Powder - Low Dose|OTHER: Moringa Powder - Medium Dose|OTHER: Moringa Powder - High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Of PF-04691502 (PI3K/mTOR Inhibitor) In Combination With Exemestane Compared With Exemestane Alone In Patients With Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DRUG: PF-04691502|DRUG: Exemestane|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of US and Evoked Motor Response-guided Placement of Continuous Femoral Nerve Block Following TKA
Status: COMPLETED
Conditions: Anesthesia|Pain|Nerve Pain|Knee Arthroplasty|Nerve Block
Interventions: DEVICE: Ultrasound|DEVICE: Ultrasound + Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized and Controlled Clinical Trial to Evaluate Bacterial Adhesion on Multi-Im® Transepithelial Components
Status: UNKNOWN
Conditions: Biofilm Formation
Interventions: DEVICE: Multi-Im Machined transepithelial component.|DEVICE: Multi-Im Nanogolden transepithelial component|DEVICE: Multi-Im Ti-Golden transepithelial component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib and Bendamustine in Chronic Lymphocytic Leukemia
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Dasatinib|DRUG: Combination of Bendamustine + Dasatinib|DRUG: Dasatinib|DRUG: Combination of Bendamustine + Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface
Status: COMPLETED
Conditions: Conjunctiva|Cornea
Interventions: PROCEDURE: conjunctival biopsy after micropulse transscleral laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Improves Sleep in Patients Undergoing Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Heart Valve Diseases|Cardiopulmonary Bypass
Interventions: OTHER: electronic acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome
Status: COMPLETED
Conditions: Down Syndrome|Polyendocrinopathies, Autoimmune|Respiratory Tract Infections|Autoimmunity
Interventions: OTHER: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Asthma Data Innovation Demonstration Project
Status: COMPLETED
Conditions: Asthma|Bronchial Diseases|Respiratory Tract Diseases|Lung Diseases, Obstructive|Lung Diseases|Respiratory Hypersensitivity|Hypersensitivity, Immediate|Hypersensitivity|Immune System Diseases
Interventions: DEVICE: Propeller Health intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Impact of High-protein Oral Supplement With Liposomal Curcumin on Inflammation Markers and Oxidative Stress in Adults Undergoing Hemodialysis.
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease 5D
Interventions: DIETARY_SUPPLEMENT: Liposomal curcumin|DIETARY_SUPPLEMENT: Food colorant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: [18]F-FAZA PET Imaging Study in Patients With Cancer of the Head & Neck, Lung, Renal Cell, Brain, Lymphoma and Neuroendocrine Tumours
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Neuroendocrine Tumours
Interventions: DRUG: 18F-FAZA PET Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Instrument Assisted Soft Tissue Mobilization on Respiratory Functions in Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD|Pulmonary Function|Soft Tissue Mobilization
Interventions: OTHER: IASTM+respiratory Exercise|OTHER: Respiratory Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Endocrine Therapy in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Node-Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Invasive Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramipril, Endothelial Function and Endothelial Progenitor Cells in Patients With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reading Remediation and Outcomes in Detention
Status: UNKNOWN
Conditions: Specific Learning Disorder (MeSH Unique ID: D000067559)|Dyslexia (MeSH Unique ID: D004410)|Conduct Disorder (MeSH Unique ID: D019955)
Interventions: BEHAVIORAL: Strategies Enhancing Reading in Older Underperf. Students
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Year Long Study to Evaluate the Safety of the Combination of Valsartan (320 mg) and Amlodipine (5 mg) in Patients With Hypertension
Status: COMPLETED
Conditions: HYPERTENSION
Interventions: DRUG: valsartan + amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Mindfulness-Based Stress Reduction Program in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Mindfulness|Upper Motor Neuron Lesion
Interventions: OTHER: Mindfulness-Based Stress Reduction (MBSR) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness, Safety, and Pharmacokinetics of TMC435 in Combination With Peginterferon Alfa-2a and Ribavirin in Hepatitis-C Infected Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: TMC435|DRUG: PegIFNα-2a|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CEND-1 in Combination With Nabpaclitaxel and Gemcitabine in Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: CEND-1|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVIDVaxStories: Randomized Trial to Reduce COVID-19 Vaccine Hesitancy in Populations of Color
Status: RECRUITING
Conditions: Vaccine Hesitancy
Interventions: BEHAVIORAL: Storytelling|BEHAVIORAL: Learn More (Active Comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging
Status: RECRUITING
Conditions: HIV Infections|Men|Treatment Adherence
Interventions: BEHAVIORAL: U=U testing messaging scripts|BEHAVIORAL: U=U adherence messaging scripts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bilateral Uterine Artery Ligation During the Cesarean Delivery of Twins
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: bilateral uterine artery ligation|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigating the Adhesion of New Adhesive to the Skin
Status: UNKNOWN
Conditions: Ileostomy - Stoma
Interventions: OTHER: Standard adhesive 1|OTHER: Standard adhesive 2|OTHER: PL4|OTHER: PL16-L
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Gliosarcoma
Interventions: DRUG: Lomustine|RADIATION: Photon Beam Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SR-WBV Training for Frail Elderly in the Skilling up Stage
Status: COMPLETED
Conditions: Poor Performance Status|Muscle Weakness
Interventions: DEVICE: SR-WBV|DEVICE: SR-WBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Project SMART Automated Pillbox Study
Status: COMPLETED
Conditions: HIV/AIDS|Cocaine Use
Interventions: DEVICE: Group A_No feedback|DEVICE: Group B_Automated feedback|DEVICE: Group C_Automated feedback + Clinician feedback|DEVICE: Group D_Automated feedback + Social Network feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Microbiome of Urologic Chronic Pelvic Pain Syndrome
Status: WITHDRAWN
Conditions: Prostatitis|Chronic Prostatitis|Interstitial Cystitis|Painful Bladder Syndrome|Bladder Pain Syndrome
Interventions: PROCEDURE: Genitourinary Specimen Collection|PROCEDURE: Collect midstream urine samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer
Status: COMPLETED
Conditions: Locally Advanced Rectal Cancer (LARC)
Interventions: DRUG: nal-IRI|PROCEDURE: Surgical resection|OTHER: Watch-and-wait|DRUG: 5-FU/LV|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of NeuroMuscular Taping on Painful Hemiplegic Shoulder
Status: COMPLETED
Conditions: Hemiplegia
Interventions: OTHER: Standard physical therapy program|OTHER: NeuroMuscular Taping (NMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 12 weekS Adjuvant dOcetaxel Plus trastuzumaB in Patients With Small, Node-negative, HER2-positive Breast cancER (SOBER)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of IPS Empress CAD Versus Polished Celtra Duo Ceramic Laminate Veneers
Status: UNKNOWN
Conditions: Tooth Discoloration|Tooth Fractures|Diastema
Interventions: OTHER: IPS Empress CAD|OTHER: polished Celtra Duo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of His-Ventricular (HV) Interval Optimisation in Cardiac Resynchronisation Therapy
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: His-Ventricular (HV) optimisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Market Clinical Follow-up Study of A-SPINE's Products
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Kyphosis|Scoliosis|Trauma|Tumor|Stenosis|Pseudoarthrosis of Spine|Deformity
Interventions: DEVICE: (1) SmartLoc (2) SmartLoc Evo (3) Winloc(4) Vigor PEEK Cervical Disc Spacer (5) Combo C (6) Polymer Lumbar Disc Spacer (7) X'Plo (8) Rainboo (9) Combo L
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phototherapy Applied in Combination With Aerobic Training
Status: COMPLETED
Conditions: Excessive Physical Exercise, Unspecified
Interventions: DEVICE: Active and Active Phototherapy|DEVICE: Active and Placebo Phototherapy|DEVICE: Placebo and active Phototherapy|DEVICE: Placebo and Placebo Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Methylnaltrexone vs Erythromycin for Facilitating Gastric Emptying Time in Critically Ill Patients
Status: TERMINATED
Conditions: Gastroparesis
Interventions: DRUG: Erythromycin|DRUG: Methylnaltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Vestibular Electrical Stimulation in Vestibular Rehabilitation
Status: COMPLETED
Conditions: Vestibular Diseases|Vestibular Disorder|Vestibular Vertigo
Interventions: OTHER: Vestibular Rehabilitation|OTHER: Vestibular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study to Assess Drug-drug Interaction Between Sitravatinib and a P-gp Inducer and an Inhibitor.
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DRUG: Sitravatinib 50 mg|DRUG: Sitravatinib 100 mg|DRUG: Itraconazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase Ib/II in Patients With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: 0.05 mL/kg DDFPe|DRUG: 0.05 mL/kg Placebo|DRUG: 0.10 mL/kg DDFPe|DRUG: 0.10 mL/kg Placebo|DRUG: 0.17 mL/kg DDFPe|DRUG: 0.17 mL/kg Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Adipose Graft Transposition Procedure (AGTP) in Patients With a Myocardial Scar: The AGTP II Trial
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: PROCEDURE: AGTP-treatment|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Patient Satisfaction With Pataday or Bepreve
Status: COMPLETED
Conditions: Eye Allergies
Interventions: DRUG: Olopatadine hydrochloride 0.2%|DRUG: Bepotastine besilate ophthalmic solution 1.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aggressive Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma|Previously Treated Myelodysplastic Syndrome|Recurrent Chronic Lymphocytic Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Indolent Adult Non-Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Plasma Cell Myeloma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hodgkin Lymphoma|Refractory Plasma Cell Myeloma|Refractory Small Lymphocytic Lymphoma|Waldenstrom Macroglobulinemia
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|BIOLOGICAL: Natural Killer Cell Therapy|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adrenocorticotropic Hormone (ACTH) for Post-op Inflammation in Proliferative Vitreoretinopathy (PVR)
Status: COMPLETED
Conditions: Proliferative Vitreoretinopathy
Interventions: DRUG: Adrenocorticotropic Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Persica 002 Phase 1b PP353 vs Placebo in the Treatment of Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: DRUG: PP353|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Pharmacokinetics of HLX70 in Healthy Adult Volunteers
Status: WITHDRAWN
Conditions: COVID 19
Interventions: DRUG: HLX70|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of the Efficacy of Peripheral Nerve Blocks in Major Open Gynaecological Cancer Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Complications|Analgesia|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Patients undergoing subcostal transversus abdominis plane block and posterior transversus abdominis plane block|PROCEDURE: Patients undergoing rectus sheat block and posterior transversus abdominis plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease: Effects After Long-term Treatment
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DEVICE: FlowOx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Navigational Investigation of Molecular Profile-Related Evidence Determining Individualized Cancer Therapy for Patients With Incurable Hematologic Malignancies (I-PREDICT Heme)
Status: TERMINATED
Conditions: Hematologic Cancer
Interventions: OTHER: Molecularly targeted treatment matched to genomic/immunophenotypic tumor profile (chosen by treating physician)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Submucosal Dissection Registry
Status: RECRUITING
Conditions: Neoplasm, Stomach|Neoplasm, Colorectal|Neoplasm, Esophagus|Neoplasm, Duodenal
Interventions: PROCEDURE: Endoscopic submucosal dissection (ESD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioral Study of Effects of Low-Level Light Therapy on Mood and Reaction Time
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Left Low Level Light Therapy|OTHER: Attention bias modification|DEVICE: Right Low Level Light Therapy|DEVICE: Sham Low Level Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis
Status: UNKNOWN
Conditions: Insulinoma|Nesidioblastosis
Interventions: DRUG: 68Ga-NOTA-exendin-4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Use of Galantamine Versus Nootropics (Memory Enhancing Drugs) in Patients With Alzheimer's Dementia Under Conditions of Daily Routine
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease|Dementia, Vascular
Interventions: DRUG: Galantamine|DRUG: Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adaptive Treatment Strategies for Improving Engagement With a Web-Based Smoking Intervention in Socially Anxious Smokers
Status: WITHDRAWN
Conditions: Social Anxiety Disorder|Tobacco Use Disorder
Interventions: BEHAVIORAL: Phase 1: Web-based intervention (MyWebQuit) with 1-way text messages|BEHAVIORAL: Phase 1: Web-based intervention (MyWebQuit) with interactive, 2-way text messages|BEHAVIORAL: Phase 2: re-engagement text messages|BEHAVIORAL: Phase 2: re-engagement emails
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Mindfulness, Mobilization of Resources, or Biofeedback on Stress Before OSCE
Status: COMPLETED
Conditions: Exam Stress|Stress, Psychological|Stress, Physiological
Interventions: OTHER: Mindfulness meditation|OTHER: Mobilization of inner resources|OTHER: Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION