pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture
Status: RECRUITING
Conditions: Femoral Neck Fractures|Prosthetic Infection
Interventions: COMBINATION_PRODUCT: antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus).|COMBINATION_PRODUCT: antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial for Effectiveness and Safety Evaluation of Hemodiafilter
Status: COMPLETED
Conditions: Renal Failure Chronic
Interventions: DEVICE: Hemodiafilter|DEVICE: Fresenius Medical Care AG & Co.KGaA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Antiperistaltic vs Isoperistaltic Billroth II + Braun Anastomosis for Postoperative Reflux
Status: UNKNOWN
Conditions: Gastric Cancer|Postoperative Complications
Interventions: PROCEDURE: Isoperistaltic Billroth II + Braun anastomosis|PROCEDURE: Antiperistaltic Billroth II + Braun anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects.
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: BRM421 Ophthalmic Solution|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Olanzapine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Rapid-Acting Intramuscular Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
Status: COMPLETED
Conditions: Cystoscopes|Baxter Anaesthesia Brand of Desflurane|Sevoflurane
Interventions: DRUG: Desflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Probiotic Treatment for Androgenetic Alopecia
Status: WITHDRAWN
Conditions: Androgenetic Alopecia|Female Pattern Baldness
Interventions: DIETARY_SUPPLEMENT: Daniel Alain Probiotic Treatment for Androgenetic Alopecia|DRUG: Topical minoxidil 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Recovery of Intestinal CD4+ and Th17 T Cells in HIV-infected Individuals on Short-term Antiretroviral Therapy
Status: UNKNOWN
Conditions: HIV Infection
Interventions: DRUG: Tenofovir-Emtricitabine plus Lopinavir/Ritonavir or Darunavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pilot Study of MSCs Iufusion and Etanercept to Treat Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Spondylitis|Spondylitis, Ankylosing|Ankylosis|Arthritis|Spondylarthritis|Spondylarthropathies|Spinal Diseases|Musculoskeletal Diseases|Bone Diseases
Interventions: BIOLOGICAL: Intravenous infusion of MSCs|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients
Status: COMPLETED
Conditions: Respiratory Failure|Mechanical Ventilation
Interventions: OTHER: Mechanical ventilation mode (PAV+ vs. ACV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CPI-613 (Devimistat) in Combination With Chemoradiation in Patients With Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma
Interventions: DRUG: CPI-613® (Dose level -1.0 250 mg/m^2)|DRUG: CPI-613® (Dose level 1.0 500 mg/m^2)|DRUG: CPI-613® (Dose level 2.0 1,000 mg/m^2)|DRUG: CPI-613® (Dose level 3.0 1,500 mg/m^2)|DRUG: CPI-613® Maximum Tolerated Dose (MTD)|DRUG: Gemcitabine|RADIATION: Intensity-modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultra-micronized Palmitoylethanolamide (Um-PEA) in Geriatric Patients With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: ultra-micronized palmitoylethanolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BOL-303259-X With Timolol 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension|Open Angle Glaucoma
Interventions: DRUG: BOL-303259-X|DRUG: Timolol maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Central Pain Among People With a Spinal Cord Injury by Evaluating Mechanisms Regulating Pain and Efficacy Testing of the TENS Apparatus
Status: UNKNOWN
Conditions: Pain|Healthy
Interventions: DEVICE: Thermal stimulation|DEVICE: Mechanical stimulation|DEVICE: Transcutaneous Electrical Nerve Stimulator (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Potential Efficacy of Convalescent Plasma to Treat Severe COVID-19 and Patients at High Risk of Developing Severe COVID-19
Status: COMPLETED
Conditions: Convalescent Plasma for COVID 19
Interventions: OTHER: convalescent plasma from recovered COVID 19 donor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms
Status: UNKNOWN
Conditions: PrEP|HIV Prevention|Adolescence|Cost-effectiveness
Interventions: BEHAVIORAL: Group-based Community Health Club|BEHAVIORAL: Individual-based Adherence Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bacterial Lysate In Preventing Asthma
Status: RECRUITING
Conditions: Wheezing|Bronchiolitis|Asthma in Children
Interventions: BIOLOGICAL: Bacterial Lysate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Respirophasic Carotid Artery Peak Velocity Variation as a Predictor of Fluid Responsiveness in Patients With Coronary Disease
Status: COMPLETED
Conditions: Coronary Artery Occlusive Disease
Interventions: OTHER: Volume expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rucaparib(CO-338;Formally Called AG-014699 or PF-0136738) in Treating Patients With Locally Advanced or Metastatic Breast Cancer or Advanced Ovarian Cancer
Status: COMPLETED
Conditions: brca1 Mutation Carrier|brca2 Mutation Carrier|Breast Cancer|Ovarian Cancer
Interventions: DRUG: rucaparib (CO-338; formally AG-014699 or PF-01367338)|GENETIC: protein expression analysis|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Unrelated Cord Blood Transplantation for Adult Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: Cord blood transplantation|RADIATION: TBI|DRUG: cyclophosphamide|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy for ACM Due to a PKP2 Pathogenic Variant
Status: RECRUITING
Conditions: Arrhythmogenic Cardiomyopathy|PKP2-ACM|PKP2-ARVC
Interventions: GENETIC: LX2020
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes
Status: COMPLETED
Conditions: Carotid Artery Stenosis|Strokes
Interventions: DRUG: Statin|DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Doxazosin to Alter the Abuse of Oxycodone
Status: TERMINATED
Conditions: Opioid-use Disorder
Interventions: DRUG: Intranasal Oxycodone|BEHAVIORAL: Cue Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of SAR240550 (BSI-201) Twice Weekly in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advance Solid Tumors
Interventions: DRUG: Iniparib (SAR240550 - BSI-201)|DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allo vs Hypomethylating/Best Supportive Care in MDS (BMTCTN1102)
Status: COMPLETED
Conditions: MDS
Interventions: PROCEDURE: Allogeneic Hematopoietic Cell Transplant|PROCEDURE: Hypomethylating Therapy / Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Methotrexate in Treating Young Patients With Solid Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: leucovorin calcium|DRUG: methotrexate|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Liuwei Dihuang Pill Versus Placebo in Presbycusis With Shen (Kidney)-Yin Deficiency
Status: RECRUITING
Conditions: Presbycusis|Age-related Hearing Loss|Hearing Disorders and Deafness
Interventions: DRUG: Liuwei Dihuang Pill (marketed product in China)|DRUG: Liuwei Dihuang Pill（placebo ）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ABT-335 (Choline Fenofibrate) Reverse Cholesterol Transport (RCT) Study
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: choline fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mills Manipulation and Mulligan PRP Affect Pain, Grip Strength and Function on Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Baseline Treatment along with Mill's manipulation|OTHER: Baseline Treatment along with Mill's manipulation and Mulligan's pain relief phenomena
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery and Muscle Function After Supplementation With Turmeric
Status: COMPLETED
Conditions: Muscle Soreness|Pain|Muscle Damage
Interventions: DIETARY_SUPPLEMENT: Turmipure Gold®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Consequences of Female Genital Mutilation on Married Women.
Status: NOT_YET_RECRUITING
Conditions: Female Genital Mutilation
Interventions: OTHER: Hamilton depression rating scale (HDRS)|OTHER: Hamilton anxiety rating scale (HARS)|OTHER: Mini international neuropsychiatric interview (MINI)|OTHER: Minnesota Multiphasic personality Inventory (MMPI)|OTHER: The Symptom Check-List-90-R (SCL-90-R)|OTHER: Socioeconomic scale (A.El Gilany, A.El Wehady and M.El Wasify)|OTHER: The female sexual function index (FSFI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Rimonabant Impact on the Regression of Asymptomatic Damage Caused by Cardiovascular Risk Factors
Status: TERMINATED
Conditions: Obesity|Microalbuminuria|Diabetes Mellitus, Type 2|Dyslipidemia
Interventions: DRUG: Rimonabant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Augmenting Hospitalization for Serious Mental Illness: Cognitive Bias Modification
Status: COMPLETED
Conditions: Depression|Bipolar Disorder|Anxiety Disorders|Psychiatric Disorder
Interventions: BEHAVIORAL: I-Change|BEHAVIORAL: Symptom Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Progressive Relaxation Exercises Applied to Caregivers on Caregiving Burden and Meaning of Life
Status: RECRUITING
Conditions: Hemiplegia
Interventions: BEHAVIORAL: Progressive relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Radiation Therapy in Combination With Darolutamide + Degarelix in Intermediate Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide|DRUG: Degarelix|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block Versus Intra-articular Steroid and Lignocaine in Knee Osteoarthritis Pain Management
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Adductor Canal Block|PROCEDURE: Intra-Articular Steroid and Lignocaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study to Evaluate the Use and Effectiveness of a Topical Ointment to Treat Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: OPA-15406|DRUG: Tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Relative Bioavailability Study of BH006 for Injection in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Bioavailability
Interventions: DRUG: BH006 for injection|DRUG: Fosaprepitant for injection+Palonosetron hydrochloride injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Informing Oral Nicotine Pouch Regulations to Promote Public Health
Status: NOT_YET_RECRUITING
Conditions: Tobacco-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Cigarette|DRUG: Nicotine Oral Pouch|DRUG: Nicotine Oral Pouch|DRUG: Nicotine Oral Pouch|DRUG: Nicotine Oral Pouch|DRUG: Smokeless Tobacco|OTHER: Survey Administration|OTHER: Text Message-Based Navigation Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
Status: COMPLETED
Conditions: Neurogenic Bladder|Spinal Cord Injuries|Quality of Life|Incontinence
Interventions: OTHER: Clean Intermittent Catheterization|OTHER: Indwelling Catheter|OTHER: Surgery|OTHER: Voiding
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect Of Bioelectric Therapy On Sternal Instability In Patients With Median Sternotomy After Heart Valve Surgery
Status: UNKNOWN
Conditions: Heart Valve Surgery
Interventions: OTHER: bioelectric therapy|OTHER: cardiac rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Study of Tin Mesoporphyrin for Neonatal Hyperbilirubinemia
Status: COMPLETED
Conditions: Glucosephosphate Dehydrogenase Deficiency|Hyperbilirubinemia|Hemolytic Disease of Newborn
Interventions: DRUG: tin mesoporphyrin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Repeated Bouts of Downhill Running and Curcumin Supplementation on Arterial Stiffness During Recovery
Status: WITHDRAWN
Conditions: Vascular Stiffness
Interventions: DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of Supervised Exercise Program Versus Mobile-Based Exercise Program in Juvenile Idiopathic Arthritis
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: OTHER: Pedi@ctivity Exercise Mobile Application Exercise Program|OTHER: Supervised Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mortality Reduction After Oral Azithromycin: Mortality Study
Status: COMPLETED
Conditions: Childhood Mortality
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRI for Non-Invasive Imaging in Neonates and Children
Status: COMPLETED
Conditions: Healthy|Cystic Fibrosis (CF)|Asthma|Bronchopulmonary Dysplasia (BPD)
Interventions: DRUG: Hyperpolarized Helium-3 MRI of the chest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of RO7239958 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Hepatitis B Virus Infection
Interventions: DRUG: RO7239958|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: White Spot Lesions Treatment in Orthodontic
Status: NOT_YET_RECRUITING
Conditions: White Spot Lesion
Interventions: DRUG: 5% sodium fluoride|DRUG: Intensive 5% sodium fluoride|DRUG: Casein Phosphopeptide-Amorphous Calcium Phosphate|DRUG: Resin infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Nevirapine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasoseptal Double Flap Versus Rescue Flap in Endoscopic Transsphenoidal Pituitary Surgery
Status: COMPLETED
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Endoscopic Transsphenoidal pituitary surgery : Double Nasoseptal Flap Technique|PROCEDURE: Endoscopic Transsphenoidal pituitary surgery : Rescue Flap Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Learn More About the Benefits and Side-effects of Drugs Rivaroxaban and Apixaban Compared to the Drug Warfarin for Stroke Prevention in Patients With Rapid and Irregular Heartbeat Which is Not Due to a Heart-valve Fault (Non-valvular Atrial Fibrillation) in the UK Routine Clinical Practice
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Apixaban (Eliquis)|DRUG: Warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Postoperative Treatment After Surgical Decompression for Lumbar Spinal Stenosis.
Status: RECRUITING
Conditions: Spinal Stenosis
Interventions: DEVICE: Device : Lombastab immo. wear for 6 weeks post-surgery the Lombastab Immo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Targeting GABA and Opioid Systems for a Pharmacotherapy for Methamphetamine Abuse
Status: COMPLETED
Conditions: Methamphetamine Abuse|Methamphetamine Dependence
Interventions: DRUG: Methamphetamine (Desoxyn®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AZD2171 to Treat Children and Adolescents With Solid Tumors or Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Refractory or Recurrent Solid Tumors|Acute Myelogenous Leukemia
Interventions: DRUG: Cediranib, AZD2171, RECENTIN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects Of Spinal Mobilization With Leg Movement on Pain And Disability in Patients With Lumbar Radiculopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Radiculopathy
Interventions: PROCEDURE: Spinal Mobilization With Leg Movement|PROCEDURE: Spinal Mobilization|PROCEDURE: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib Plus Penpulimab in Advanced Non-Small-Cell Lung Cancer Previously Treated With PD-1/PD-L1 Inhibitors
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Plus Penpulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Ixempra Versus Taxol in Adjuvant Therapy of Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Ixabepilone (Ixempra)|DRUG: Paclitaxel (Taxol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Stroke Riskometer Apps In Improving Awareness and Stroke Risk Probability
Status: UNKNOWN
Conditions: Stroke|Cardiovascular Diseases|Risk Factor, Cardiovascular
Interventions: DEVICE: Stroke Riskometer Application|OTHER: Informational Leaflets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Fat Quality on Glycemic Regulation and Gut Microbiota After a Short-time Intervention in Healthy Individuals
Status: COMPLETED
Conditions: Postprandial Blood Glucose|Gut Microbiota|Satiety
Interventions: OTHER: Saturated fat 14.9 E%|OTHER: Polyunsaturated fat 13.6 E%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Measuring the Effectiveness, Safety, and Tolerability of BMS-986278 in Participants With Lung Fibrosis
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: OTHER: BMS-986278 Placebo|DRUG: BMS-986278
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery
Status: COMPLETED
Conditions: Anesthesia , Analgesia
Interventions: DRUG: Dexmedetomidine|DRUG: Magnesium sulfate|DRUG: Narcotic Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of rTMS on Symptoms and Cognitive Function in Patients With Psychiatric Disorders
Status: COMPLETED
Conditions: Schizophrenia|Major Depressive Disorder
Interventions: DEVICE: rTMS in schizophrenia Controls|DEVICE: rTMS in schizophrenia patients|DEVICE: rTMS in major depressive disorders controls|DEVICE: rTMS in major depressive disorders patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Pancreatic Ductal Adenocarcinoma|Biliary Tract Cancers|Esophageal Squamous Cell Carcinoma|Triple Negative Breast Cancer|Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer|Head and Neck Squamous-Cell Carcinoma
Interventions: DRUG: ABBV-400
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Prehab for Lumbar Spinal Stenosis
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis|Prehabilitation
Interventions: OTHER: Prehab for LSS|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Interoceptive Exposure Training in Anorexia Nervosa
Status: ACTIVE_NOT_RECRUITING
Conditions: Anorexia Nervosa
Interventions: DRUG: Isoproterenol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety, Tolerability, and Preliminary Efficacy of HCL001 Cell Injection (Homologous Allogeneic Hepatocytes) in Patients With Decompensated Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Decompensated Cirrhosis
Interventions: DRUG: HCL001 cell (homologous allogeneic hepatocytes) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream
Status: COMPLETED
Conditions: Skin Care
Interventions: COMBINATION_PRODUCT: Skin Care Cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Neuromuscular Bandage Technique Against Jones Technique After the Supraespinatus Muscle Tendon Suture
Status: COMPLETED
Conditions: Pain
Interventions: PROCEDURE: KT|PROCEDURE: SCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Factors for Ablation of Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Catheter Ablation|Spectral Analysis|Vectorcardiography|Heart Rate Variability
Interventions: DEVICE: Catheter ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study.
Status: UNKNOWN
Conditions: Breast Cancer Stage IV
Interventions: DRUG: Palbociclib|DRUG: Ribociclib|DRUG: Abemaciclib|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Tamoxifen|DRUG: Fulvestrant|DRUG: Exemestane|DRUG: Alpelisib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Conservative Treatment of PAS With or Without IIL
Status: RECRUITING
Conditions: Placenta Accreta|Cesarean Hysterectomy|Pelvic Devascularization
Interventions: PROCEDURE: Ligation of the bilateral internal iliac arteries|PROCEDURE: Shehat's technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Comparative Efficacy of an Over the Counter Light Therapy Mask vs Over the Counter Topical Benzoyl Peroxide 2.5% and Used in Combination With Over the Counter Adapalene Gel 0.1% for Mild to Moderate Acne
Status: WITHDRAWN
Conditions: Acne
Interventions: DRUG: Neutrogena ® Light Therapy Acne Mask (MASK)|DRUG: Topical OTC benzoyl peroxide 2.5% gel and OTC adapalene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketoconazole, Dexamethasone, and Hydrocortisone in Treating Patients With Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: dexamethasone|DRUG: ketoconazole|DRUG: therapeutic hydrocortisone|PROCEDURE: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Incremental Initiation of Haemodialysis Preserve Native Kidney Function?
Status: UNKNOWN
Conditions: Kidney Failure|Dialysis
Interventions: PROCEDURE: Standard Haemodialysis|PROCEDURE: Incremental dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Training Program Provided to Primipara Pregnant Women Through the Motivational Interview Method on Their Fear of Childbirth, Childbirth Self-Efficacy and Delivery Mode
Status: COMPLETED
Conditions: Fear of Childbirth|Childbirth Self-efficacy|Mode of Delivery|Motivational Interview
Interventions: BEHAVIORAL: Antenatal education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Efficacy and Safety of MK2578 for the Treatment of Anemia in Patients With Kidney Disease (MK2578-003-AM03-EXT12)
Status: TERMINATED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: MK2578 1mcg for every 600 Units (U) of Epogen® (epoetin alfa) received per week at Baseline|DRUG: MK2578 1 mcg for every 350 U of Epogen (epoetin alfa) received per week at Baseline|DRUG: MK2578 1 mcg for every 200 U of Epogen (epoetin alfa) received per week at Baseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Topical Administration of Common Drugs on Postoperative Bleeding and Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Hemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: Bupivacaine|DRUG: Adrenaline|DRUG: tranexamic acid plus saline|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Follow-up of Patients With Alcoholic Liver Cirrhosis Who Had Administered Cellgram-LC in PMC-P-07 Study
Status: RECRUITING
Conditions: Alcoholic Cirrhosis
Interventions: BIOLOGICAL: Cellgram-LC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Functional Relevance of Dopamine Receptors in Healthy Controls and Patients With Schizophrenia: Characterization Through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography
Status: RECRUITING
Conditions: Schizoaffective Disorder|Schizophrenia
Interventions: DRUG: PET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity, Safety, Reactogenicity, Efficacy, Effectiveness and Lot Consistency of FluBlok
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluBlok®|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IV Ascorbic Acid in Peritoneal Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Vitamin C|GLUT3
Interventions: DRUG: Ascorbic acid|DRUG: FOLFOXIRI Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Anti-PD-1 Antibody in Patients With Advanced Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Camrelizumab|COMBINATION_PRODUCT: US/CT-guided Percutaneous Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empower-Grief: A Study on a Selective Intervention to Prevent Prolonged Grief Disorder
Status: RECRUITING
Conditions: Grief Disorder, Prolonged
Interventions: OTHER: EMPOWER|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate to Severe Systemic Sclerosis
Interventions: DRUG: KHK4827|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Reduction With ESD- Versus APC-TORe
Status: RECRUITING
Conditions: Obesity|Roux-en-y Anastomosis Site|Weight Gain
Interventions: PROCEDURE: E-TORe|PROCEDURE: c-TORe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Adverse Events and How Single Ascending Doses of ABBV-141 Move Through the Body of Healthy Adult Western and Asian Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: ABBV-141|DRUG: Placebo for ABBV-141|DRUG: ABBV-141|DRUG: Placebo for ABBV-141
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease
Status: WITHDRAWN
Conditions: Cytomegalovirus Infections|Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Cidofovir|DRUG: Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Usability and Satisfaction Test to the Wearable Walking-assist Robot (GEMS-H) in the Community-dwelling Healthy Adults
Status: COMPLETED
Conditions: Gait Disorders in Old Age
Interventions: DEVICE: Training with Gait Enhancing and Motivating System (GEMS-H) Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Implementation of Realistic Simulation as Patient Safety Improvement Method
Status: UNKNOWN
Conditions: Compliance Behavior
Interventions: BEHAVIORAL: Realistic simulation|BEHAVIORAL: control group|BEHAVIORAL: Simulation workshop|BEHAVIORAL: Test realistic simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Phosphate Binding With Sevelamer in Stage 3 Chronic Kidney Disease
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Cardiovascular Diseases
Interventions: DRUG: Sevelamer carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Liberal Versus Restrictive Transfusion During Symptomatic Moderate Anemia After Hip Arthroplasty
Status: TERMINATED
Conditions: Arthroplasty, Hip
Interventions: OTHER: Red blood cell transfusion|DRUG: Voluven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guidance Versus Electrical Stimulation for Continuous Popliteal-Sciatic Nerve Blocks
Status: COMPLETED
Conditions: Postoperative Pain|Foot Numbness
Interventions: PROCEDURE: Popliteal catheter placed via ultrasound or electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Transradial Access for Primary PCI in STEMI Patients to Prevent RAO
Status: RECRUITING
Conditions: ST Segment Elevation Myocardial Infarction
Interventions: PROCEDURE: distal radial artery|PROCEDURE: proximal radial aretry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Ketorolac|DRUG: Chlorhexidine 2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Stem Cell Therapy for the Treatment of Severe Coronary Ischemia
Status: COMPLETED
Conditions: Coronary Ischemia|Coronary Disease|Coronary Artery Disease|Coronary Atherosclerosis|Coronary Arteriosclerosis
Interventions: BIOLOGICAL: MESENDO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA)
Status: UNKNOWN
Conditions: Cholecystitis, Acute
Interventions: PROCEDURE: Laparoscopic Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carvedilol + VSL#3 Versus Endoscopic Variceal Ligation for Primary Prophylaxis of Esophageal Variceal Bleeding in Cirrhotic Patients Non Responder to Carvedilol.
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Carvedilol+VSL#3|PROCEDURE: Endoscopic variceal ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clobazam in Subjects With Lennox-Gastaut Syndrome
Status: COMPLETED
Conditions: Epilepsy|Epilepsy, Generalized|Seizures
Interventions: DRUG: Clobazam Low Dose|DRUG: Clobazam High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A REAl-life Study on Short-term DAPT in Patients With Ischemic Stroke or TIA
Status: UNKNOWN
Conditions: Ischemic Stroke|TIA
Interventions: DRUG: Aspirin|DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy
Status: COMPLETED
Conditions: Hepatic Encephalopathy|Cirrhosis
Interventions: DRUG: Rifaximin|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Patients starting a treatment with Doxorubicin and Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate
Status: UNKNOWN
Conditions: Labor Preterm Requiring Hospitalization
Interventions: DRUG: nifedipen|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Results of FilmArray® Gastro-intestinal Panel and Serum Procalcitonin in Acute Colitis and Infectious Diarrhea in the ER
Status: COMPLETED
Conditions: Acute Diarrhea|Acute Colitis of Presumed Infectious Origin
Interventions: DEVICE: Filmarray PCR multiplex-PCT assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Instr. vs. Non-instr. Posterolateral Spinal Fusion in Patients With Spinal Stenosis and Degenerative Listhesis
Status: COMPLETED
Conditions: Spinal Stenosis|Spondylolisthesis Degenerative|Spinal Fusion
Interventions: PROCEDURE: Instrumented posterolateral spine fusion.|PROCEDURE: Non-instrumented posterolateral spine fusion.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ultrapulse Carbon Dioxide Laser Treatment in Eyelid Tumors
Status: RECRUITING
Conditions: Eyelid Tumor|Xanthelasma Palpebrarum|Pigmented Nevi|Keratosis
Interventions: PROCEDURE: Ultra-pulsed Carbon Dioxide Laser
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Detecting and Addressing Preclinical Disability
Status: COMPLETED
Conditions: Back Pain|Coronary Artery Disease|Chronic Obstructive Pulmonary Disease|Diabetes|Hypertension|Multiple Sclerosis|Osteoporosis|Osteoarthritis|Rheumatoid Arthritis|Stroke
Interventions: OTHER: Tailored advice from a physiotherapist and/or an occupational therapist through the myOSCAR patient portal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impacts of Metabolic Variation on Neuroendocrine Control of Reproduction
Status: COMPLETED
Conditions: Neuroendocrine Reproductive Status
Interventions: DIETARY_SUPPLEMENT: effect of metabolic variations on LH pulsatility
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain-relieving Methods After Laparoscopic Hemicolectomy
Status: RECRUITING
Conditions: Postoperative Pain|Nerve Block
Interventions: PROCEDURE: Transabdominal plane block|PROCEDURE: Quadratus lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled, Multicenter, Noninferiority Clinical Study of Perioperative and Oncological Safety in Patients With Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Department of Anorectal Surgery, Changhai Hospital Affiliated to Naval Medical University
Interventions: PROCEDURE: Laparoscopic radical resection of low rectal cancer with transanal specimens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Botox Injection in Anterior Belly of Digastric on Skeletal Relapse Following Mandibular Advancement Surgery
Status: NOT_YET_RECRUITING
Conditions: Orthognathic Relapse
Interventions: DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interscalene vs. Superficial Cervical Block vs. Combination for Analgesia After Clavicle Fracture
Status: UNKNOWN
Conditions: Clavicle Fracture
Interventions: PROCEDURE: SCPB|PROCEDURE: ISB|PROCEDURE: SCPB + ISB|DRUG: Bupivacaine hydrogen chloride , epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Merged 3D Imaging Improve Contact Force and Long Term Procedure Outcome in Atrial Fibrillation?
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: FAM 3D map group|PROCEDURE: FAM-CT 3D map group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Access and Affordability of Adult Hearing Healthcare
Status: RECRUITING
Conditions: Hearing Loss
Interventions: BEHAVIORAL: Hearing Evaluation|DEVICE: Over-the-Counter Hearing Aid (OTC HA) Fitting and Orientation|BEHAVIORAL: Four Weeks of Aural Rehabilitation|DEVICE: Provision of Over-the-Counter Hearing Aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT