pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Allergen Challenge Trial of IRL201104 in Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: IRL201104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confirmation of Correct Tracheal Tube Placement in Newborn Infants - a Randomized Control Trial
Status: COMPLETED
Conditions: Newborn Infant
Interventions: PROCEDURE: Flow waves|PROCEDURE: ECO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of GSK1399686 in Patients With Mild to Moderately Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: GSK1399686
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Status: COMPLETED
Conditions: Disorder of Bone Density and Structure, Unspecified
Interventions: DRUG: Recombinant human insulin like growth factor-1 (rhIGF-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrahepatic Reinfusion of CD133+ Stem Cells in Cirrhotic Patients
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: autologous highly purified CD133+ stem cells (SCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pragmatic Same-day COVID-19 Ring Prophylaxis for Adult Individuals Exposed to SARS-CoV-2 in Switzerland
Status: COMPLETED
Conditions: Prevention of COVID-19
Interventions: DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Deferasirox-calcium-vitamin D3 Therapy for Postmenopausal Osteoporosis (PMOP)
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Deferasirox and calcium-vitamin D3|DRUG: Calcium-vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Curcumin C-3 Complex in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Depression
Interventions: DIETARY_SUPPLEMENT: Super-Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of Single Dose Intravenous Moxifloxacin in Pediatric Patients
Status: COMPLETED
Conditions: Infections
Interventions: DRUG: Moxifloxacin (Avelox, BAY12-8039)|DRUG: Moxifloxacin (Avelox, BAY12-8039)|DRUG: Moxifloxacin (Avelox, BAY12-8039)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Duodenal-Ileal Diversion in Obese Patients Undergoing Primary Sleeve or Those With Inadequate Weight Loss After Sleeve
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid
Interventions: DEVICE: Self Forming Magnets (SFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Radiation Dose and Contrast Use During Cryoballoon Pulmonary Vein Isolation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Cryoballoon Pulmonary Vein Isolation - PVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy Of Instrument-Assisted Soft Tissue Mobilization At Lumbar Region Disc Herniations
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Instrument-assisted Soft Tissue Mobilization
Interventions: OTHER: Instrument-assisted soft tisue mobilization|OTHER: Traditional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Green Tea Extracts for Mild-to-moderate Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DIETARY_SUPPLEMENT: Green tea|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK Subtrial in Adolescent Patients With HAE Type I or II Participating in the KVD900-302 Trial
Status: RECRUITING
Conditions: Hereditary Angioedema
Interventions: DRUG: KVD900 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pravastatin for Acute Myocardial Infarction With Minimally to Mildly Increased Levels of Serum Cholesterol Study
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Chemoradiotherapy (CCRT) With Paclitaxel Plus Cisplatin in LA Non-small-cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Concurrent chemoradiotherapy (paclitaxel plus cisplatin plus radiotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DIAGNOSTIC_TEST: Cytogenetic analysis (FISH) for EZH2 gene deletion. -Real time PCR for PHF 19 gene expression.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
Status: RECRUITING
Conditions: NASH|Cirrhosis, Liver
Interventions: DRUG: Resmetirom|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Out-of-Hospital Intubation With Metal Single Use Laryngoscope Blades
Status: COMPLETED
Conditions: Cardiac Arrest|Coma|Major Trauma|Respiratory Distress|Shock
Interventions: DEVICE: MacIntosh Green Lite (metal single use laryngoscope blades)|DEVICE: MacIntosh Green Spec II (metal reusable laryngoscope blades)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Joint Mobilization on Alpha Motoneuron Reflex Excitability
Status: COMPLETED
Conditions: Muscle Spasticity|Spinal Cord Injury|Stroke|Craniocerebral Trauma
Interventions: OTHER: joint mobilization techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: [68Ga]Ga-P15-041 PET/CT in Variety of Bone Tumors
Status: RECRUITING
Conditions: Bone Tumor|Bone Metastases
Interventions: DRUG: [68Ga]Ga-P15-041
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quickstart of Nexplanon® at Medical Abortion
Status: COMPLETED
Conditions: Early Pregnancy Termination|Medical Abortion|Postabortion Contraception
Interventions: DRUG: Mifepristone|DRUG: etonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: GEMHDM2014 : Gem-HDM HDT and ASCT for Relapsed/ Refractory Lymphoma
Status: TERMINATED
Conditions: Hodgkin's Lymphoma - Relapsed/Refractory|Non-Hodgkin's Lymphoma - Aggressive|Follicular Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Melphalan|OTHER: ASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facial Serum and Mask and Ready-to-drink Jelly From Thai Rice
Status: NOT_YET_RECRUITING
Conditions: Rice Serum|Rice Mask|Rice Jelly
Interventions: OTHER: Study 1: Facial serum with alpha albutin|OTHER: Study 1: Facial serum with Tubtim Chumpae rice extract|OTHER: Study 2: Facial mask with Hom Pathum rice extract|OTHER: Study 3: Control jelly|OTHER: Study 3: Jelly with Tubtim Chumpae rice|OTHER: Study 3: Jelly with Hom Pathum rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of RO7303509 in Participants With Systemic Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: RO7303509|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling Shoulder Muscles on a Head Turning Task in Participants Aged 30-50 With Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Psychomotor Disorders
Interventions: OTHER: Dry Needling|OTHER: Sham Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Oral Ibuprofen on Anesthetic Efficacy of Inferior Alveolar Nerve Block With Supplemental Buccal and Lingual Infiltrations Using Articaine in Mandibular Molar Teeth With Irreversible Pulpitis
Status: NOT_YET_RECRUITING
Conditions: Mandibular Molar Teeth With Symptomatic Irreversible Pulpitis
Interventions: DRUG: Oral Ibuprofen (Abbott, Egypt)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Continuous and Pulsed Ultrasound Treatments in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DEVICE: ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study
Status: WITHDRAWN
Conditions: Periimplantitis|Oral Surgery
Interventions: DEVICE: Implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Implementation Enhancement Strategy To Improve Teachers' Intention to Implement Evidence-Based Practices
Status: COMPLETED
Conditions: Child Behavior Disorders|Implementation Science|Adolescent Problem Behavior at School|Healthcare Providers
Interventions: BEHAVIORAL: Pre-implementation enhancement strategies (SC-PIES)|OTHER: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate KIN-3248 in Participants With Advanced Tumors Harboring FGFR2 and//or FGFR3 Gene Alterations
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor, Adult|Intrahepatic Cholangiocarcinoma|Urothelial Carcinoma
Interventions: DRUG: KIN-3248
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Therapy in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DIETARY_SUPPLEMENT: Oral magnesium sulfate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Surgical Resectability After FOLFIRINOX Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Cancer: the Role of Diffusion Weighted Magnetic Resonance Imaging, Radiomics and Liquid Biopsy (PeRFormanCe Trial)
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DIAGNOSTIC_TEST: Imaging analysis of CT-scan and MRI with radiomics and genetic analysis of peripheral blood samples and questionnaires.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS-FNA with Corkscrew technique|DEVICE: Expect 19 G Flex needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Soft Tissue Profile Changes Following Autogenous Fat or Onlay Polyetheretherketone (PEEK) Augmentation Versus Sliding Genioplasty for Correction of Deficient Chin
Status: UNKNOWN
Conditions: Patients With Deficient Chin
Interventions: PROCEDURE: fat filler,PEEK,sliding genioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Dual Antiplatelet Therapy Versus Rivaroxaban In Atrial Fibrillation Patients Treated With Left Atrial Appendage Closure
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Appendage|Hemorrhage
Interventions: DRUG: Rivaroxaban 10 mg qd|DRUG: Rivaroxaban 15 mg qd|DRUG: DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Zn-DDC|DRUG: Lanalidomide with Zn-DDC|DRUG: Pomalidomide with Zn-DDC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease
Interventions: DEVICE: GENUS device (Active Settings)|DEVICE: GENUS device (Sham Settings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glycemic Outcomes and Safety With Minimed 780G System in Children With Type 1 Diabetes Aged 2-6 Years
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: DEVICE: Medronic 780G insulin pump
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The VL3 Videolaryngoscope for Elective Tracheal Intubation in Adults
Status: COMPLETED
Conditions: Difficult Airway Intubation
Interventions: DEVICE: Videolaryngoscopy with VL3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Application to Improve the Quality of Colonoscopy in Colorectal Cancer Screening Program (PrepColon APP)
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Premalignant Colon Lesions
Interventions: OTHER: Mobile application for colonoscopy preparation instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biomarkers of Sulforaphane/Broccoli Sprout Extract in Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: BroccoMax®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: End tidal CO2 (EtCO2)|DEVICE: Transcutaneous CO2 (TCO2)|DIAGNOSTIC_TEST: Capillary CO2 (CapCO2)|DIAGNOSTIC_TEST: Arterial blood gas (ABG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam
Status: COMPLETED
Conditions: Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Interventions: DRUG: Sevoflurane based inhalation anesthesia|DRUG: Remimazolam based total intravenous anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
Status: COMPLETED
Conditions: Muscle Soreness|Delayed-onset Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Polyherbal supplement: ReWin(d) vs Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lundbeck TOMs Orthostatic Hypotension
Status: COMPLETED
Conditions: Orthostatic Hypotension|Idiopathic Parkinson Disease
Interventions: DRUG: Droxidopa 100 MG [Northera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of Different Hypothermia Temperatures in Patients Recovered From Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Non-environmental Hypothermia|Cardiac Arrest
Interventions: PROCEDURE: Endovascular Cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Strategy for Unstable Coronary Plaque in Patients Presenting to Emergency Department for Chest Pain Suspected of Coronary Artery Disease
Status: RECRUITING
Conditions: Atherosclerosis
Interventions: DIAGNOSTIC_TEST: 18F-Na PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Retentive Strength of Denture Adhesives on Various RR Ridges
Status: COMPLETED
Conditions: Retentive Strength of Denture Adhesives
Interventions: DRUG: polymyxin b/trimethoprim ophthalmic, Carboxymethyl cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimized Biventricular Pacing Allograft Recipients
Status: TERMINATED
Conditions: Dilated Cardiomyopathy|Ischemic Cardiomyopathy
Interventions: DEVICE: BiVP|DEVICE: AAI Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy and Safety Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Osmotic Release Oral System (OROS) Methylphenidate Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Movement Pattern Training in People With Intra-articular, Prearthritic Hip Disorders
Status: COMPLETED
Conditions: Chronic Hip Joint Pain|Prearthritic Hip Disease
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) in Depression
Status: TERMINATED
Conditions: Depression
Interventions: DEVICE: rTMS 5 x weekly|DEVICE: rTMS 3 times weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic and Prognostic Accuracy of Gold Nanoparticles in Salivary Gland Tumours
Status: COMPLETED
Conditions: Carcinoma Ex Pleomorphic Adenoma of Salivary Glands|Pleomorphic Adenoma of Salivary Glands
Interventions: DIAGNOSTIC_TEST: CD24-Gold Nanocomposite expression using Real-time quantitative polymerase chain reaction|DIAGNOSTIC_TEST: non-conjugated CD24 expression using Real-time quantitative polymerase chain reaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib or Observation in Treating Patients Who Have Undergone First-Line Chemotherapy for Ovarian Cancer, Peritoneal Cancer, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICE T for Post GYN Surgery Pain
Status: COMPLETED
Conditions: Opioid Substitution Treatment
Interventions: DRUG: Ketorolac|DRUG: Opioids|OTHER: Ice Packs|DRUG: Tylenol|DRUG: Motrin|DRUG: dilaudid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effect of Choosing of Preoperative Intravenous Fluid Type on the Postoperative Nausea, Vomiting, Anxiety and Pain After Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Post Operative Pain|Nausea and Vomiting, Postoperative|Anxiety
Interventions: OTHER: preoperative IV 0.9% saline 200 ml|OTHER: preoperative dextrose 5% 200 ml|OTHER: preoperative and intraoperative dextrose 5% 200 ml
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization
Status: ACTIVE_NOT_RECRUITING
Conditions: Contraception
Interventions: PROCEDURE: Blood draw|DEVICE: ESSURE (BAY1454032)|PROCEDURE: Laparoscopic tubal sterilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mobile Cognitive Behavioral Therapy for Medical and Graduate Students
Status: RECRUITING
Conditions: Anxiety Disorders|Depression
Interventions: BEHAVIORAL: Clinician Delivered CBT|BEHAVIORAL: Supplemental MAYA App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Olaparib in Combination With AZD5363 (ComPAKT)
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: olaparib|DRUG: AZD5363
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anticholium® Per Se
Status: COMPLETED
Conditions: Shock, Septic|Sepsis|Perioperative Period
Interventions: DRUG: Physostigmine|DRUG: Isotonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lumbar Transcutaneous Electrical Nerve Stimulation on Exercise Performance in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: High-frequency transcutaneous electrical nerve stimulation|OTHER: Low-frequency transcutaneous electrical nerve stimulation|OTHER: Sham transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BR in Patients With CLL With Comorbidities and/or Renal Dysfunction
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Open-Label, Randomized, Parallel Group, Placebo-Controlled, Single-Center Study to Assess Anti-microbial Efficacy and Safety of DCN01 Compared to Unisol® Following Topical Periocular Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Ocular Infection
Interventions: DRUG: DCN01|DRUG: Unisol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Use of Dexketoprofen Trometamol, Pethidine Hcl, Tramadol Hcl and Their Combinations for Postoperative Pain Management in Laparoscopic Nissen Fundoplication
Status: UNKNOWN
Conditions: Laparoscopic Nissen Fundoplication
Interventions: DRUG: dexketoprofen trometamol|DRUG: tramadol hydrochloride|DRUG: pethidine hydrochloride|DRUG: dexketoprofen trometamol + tramadol hydrochloride|DRUG: dexketoprofen trometamol + pethidine hydrochloride|DRUG: vitamin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Prediction of the Effect of EECP on HR-NICE Patients
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: DEVICE: real EECP|DEVICE: sham EECP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 3-Year Clinical Evaluation Of Endocrown Restorations With Two Different Materials
Status: ACTIVE_NOT_RECRUITING
Conditions: Endodontically Treated Teeth
Interventions: OTHER: resin nanoceramic block|OTHER: zirconia-reinforced lithium silicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
Status: COMPLETED
Conditions: Corneal Staining
Interventions: DEVICE: Biotrue MPS|DEVICE: Investigational MPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reducing Medication Errors and Time to Drugs Delivery During Pediatric Cardiopulmonary Resuscitation: a Multicenter RCT
Status: COMPLETED
Conditions: Resuscitation|Pediatrics
Interventions: DEVICE: PedAMINES™ / Conventional Method|DEVICE: Conventional Method / PedAMINES™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: DRUG: vitamin A|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: L-carnitine vs Placebo for the Treatment of Muscle Cramps After Imatinib in Gastrointestinal Stromal Tumors
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors (GISTs)
Interventions: DRUG: L-carnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy
Status: UNKNOWN
Conditions: Intractable Epilepsy
Interventions: OTHER: Reduction of anti-epileptic medications|PROCEDURE: No drug change
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: To Evaluate the Effects of NMRA-335140 on Symptoms of Major Depression in Participants With Bipolar II Disorder.
Status: RECRUITING
Conditions: Major Depressive Episode Associated With Bipolar II Disorder
Interventions: DRUG: NMRA-335140 80 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore
Status: RECRUITING
Conditions: Oral Leukoplakia|Oral Leukoplakia of Tongue|Oral Leukoplakia of Gingiva|Oral Lichen Planus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Effectiveness of the Probiotic E. Coli Strain M17 in Treating Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DIETARY_SUPPLEMENT: E. Coli Strain M17 Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Inhaled nitric oxide|OTHER: Sham inhaled nitric oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of a Personalised Nutrition and Activity Programme for People With Lung Cancer Over 65 Years
Status: COMPLETED
Conditions: Lung Neoplasm Malignant|Mesothelioma; Lung
Interventions: OTHER: Tailored nutrition and physical activity programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEOadjuvant PembRolizumab In Stratified Medicine - ColoRectal Cancer
Status: RECRUITING
Conditions: Adenocarcinoma of the Colon
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Left Atrium Appendage Closure in NVAF Patients With High Risk of Ischemic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation|Stroke
Interventions: DEVICE: Left atrial appendage closure procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I, Randomized, Double-blinded, Placebo-Controlled Dose De-escalation Study to Evaluate Safety and Immunogenicity of Alum Adjuvanted Zika Virus Purified Inactivated Vaccine (ZPIV) in Adults in a Flavivirus Endemic Area
Status: COMPLETED
Conditions: Zika Virus Infection
Interventions: OTHER: Placebo|BIOLOGICAL: Zika Virus Purified Inactivated Vaccine (ZPIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: COSMIC Study - Comparing Open Scarf/Akin Osteotomy and Minimally Invasive Chevron/Akin. A Feasibility Study
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: PROCEDURE: Minimally Invasive Chevron/Akin osteotomy|PROCEDURE: Open Scarf/Akin osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric Endoscopy
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol (Group P)|DRUG: Propofol (Group DP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action-based Cognitive Remediation for First Episode Psychosis
Status: COMPLETED
Conditions: Cognitive Impairment|Psychosis
Interventions: BEHAVIORAL: Action-based cognitive remediation|OTHER: Waitlist Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Octreotide in Preventing Pancreatic Fistula After Pancreaticoduodenectomy (PD) in Patients With Soft Pancreas
Status: COMPLETED
Conditions: Pancreatic Fistula
Interventions: DRUG: Inj. Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesh Vs Pledgets for Repair of Paraesophageal Hernia
Status: RECRUITING
Conditions: Paraesophageal Hernia|GERD
Interventions: DEVICE: OviTex Mesh|OTHER: Pledgeted sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Intravenous Iron Sucrose in Patients With Hip Fracture to Prevent Perioperative Anemia
Status: UNKNOWN
Conditions: Hip Fracture|Surgical Intervention
Interventions: DRUG: Iron sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Multiple Dose Study Of PF-06678552 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06678552|DRUG: Placebo|DRUG: PF-06678552|DRUG: Placebo|DRUG: PF-06678552|DRUG: Placebo|DRUG: PF-06678552|DRUG: Placebo|DRUG: PF-06678552|DRUG: Placebo|DRUG: PF-06678552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Oral AB1010 in Adult Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: masitinib (AB1010)|DRUG: masitinib (AB1010)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cardiovascular Risk Markers in Psoriasis Patients Treated With Secukinumab
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Secukinumab|OTHER: Placebo|OTHER: Placebo|DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery
Status: UNKNOWN
Conditions: Mitral Regurgitation
Interventions: DEVICE: percutaneous treatment by implanting a Mitra Clip device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Origin of the Neonatal Gut Microbiota and Probiotic Intervention
Status: COMPLETED
Conditions: Microbiota
Interventions: DRUG: Probiotic Blend Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Use of Direct Oral Anticoagulants in UK Clinical Practice For Patients With a First Stroke Attributable to Nonvalvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban|DRUG: Apixaban|DRUG: Rivaroxaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aclidinium/Formoterol Fixed Combination Dose Finding Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide and formoterol|DRUG: Aclidinium bromide and formoterol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over an 8-week Treatment Period in Adult Subjects With Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Delgocitinib cream|DRUG: Delgocitinib cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Determine Blood Pressure Interaction Between TC-5214 and Anti-Hypertensive Medications (Calcium Channel Blockers, Beta Blockers, and ACE Inhibitors) in Patients With Chronic Hypertension
Status: TERMINATED
Conditions: Chronic Hypertension
Interventions: DRUG: TC-5214|DRUG: TC-5214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in Combination With Myo-inositol in Young Women With Polycystic Ovary Syndrome (PCOS) and Insulin Resistance
Status: COMPLETED
Conditions: PCOS|Polycystic Ovary Syndrome
Interventions: DRUG: Drospirenone Ethinyl estradiol|DRUG: Drospirenone Ethinyl estradiol Myo-inositol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Improving Informed Consent for Palliative Chemotherapy
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer|Metastatic Pancreatic Cancer|Unresectable Pancreatic Cancer
Interventions: OTHER: Investigational informed consent for chemotherapy|OTHER: Usual, standard-of-care informed consent for chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of Trunk Impairment on Fatigue and Balance
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: DIAGNOSTIC_TEST: Trunk Impairment Scale (TIS), PedsQLTM Multidimensional Fatigue Scale (PedsQL-MFS), Pediatric Balance Scale (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Early Postoperative CRRT After Liver Transplantation in ACLF Patients With Overt HE
Status: UNKNOWN
Conditions: Acute-On-Chronic Liver Failure|Hepatic Encephalopathy
Interventions: DEVICE: eCRRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of an Adherence Plan to Help HIV-Positive Patients Take Their First Anti-HIV Medications Correctly
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nelfinavir mesylate|DRUG: Efavirenz|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Computer Assisted Instrument Guidance (CAIG) for Orthopedic Peripheral Nerve Blocks
Status: COMPLETED
Conditions: Peripheral Nerve Blocks
Interventions: DEVICE: Peripheral Nerve Blocks with CAIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Two Modes of Mechanical Ventilation on Metabolic Demands and Respiratory Mechanics
Status: UNKNOWN
Conditions: Mechanical Ventilation
Interventions: PROCEDURE: BIPAP|PROCEDURE: APRV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Isolation of the Operative Field Influences the Survival Rate of Composite Restorations
Status: COMPLETED
Conditions: Dental Caries in Children
Interventions: PROCEDURE: Rubber dam isolation|PROCEDURE: Relative isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DERMALIX Efficacy on Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot|Diabetic Foot Ulcer
Interventions: OTHER: Standard Dressing|DEVICE: DERMALIX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare Endoscopic and Open Methods of Vein Harvesting for Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Autovenous Conduit for Coronary Artery Bypass Grafting
Interventions: PROCEDURE: Open vein harvesting|PROCEDURE: Endoscopic vein harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tissue Sample Collection From Patients With Fanconi Anemia
Status: COMPLETED
Conditions: Fanconi Anemia|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: OTHER: biologic sample preservation procedure|PROCEDURE: biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eradication of Helicobacter Pylori in the Management of Stage IE & IIE-1 Primary Low-grade B Cell Lymphoma of MALToma
Status: COMPLETED
Conditions: MALT Lymphoma
Interventions: OTHER: Omeprazole, Amoxicillin, Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala Application on Anxiety Level and Caregiver Burden in Palliative Care
Status: COMPLETED
Conditions: Palliative Care|Caregiver|Anxiety|Mandala|Caregiver Burden
Interventions: OTHER: Mandala|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Caregiver-Child Interaction and Health Behaviors
Status: COMPLETED
Conditions: Early Childhood Caries|Caregiver-Child Coercion
Interventions: BEHAVIORAL: Behavioral Intervention|OTHER: Cognitive Intervention|OTHER: Interpretation Bias Intervention|OTHER: Evaluative Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Empowering Economically Insecure Parents to Manage Child Anxiety
Status: NOT_YET_RECRUITING
Conditions: Project EMPOWER|Online Resources and Referrals
Interventions: BEHAVIORAL: Project EMPOWER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Beetroot Juice Ingestion and Vertical Jump Performance
Status: COMPLETED
Conditions: Dietary Supplements
Interventions: DIETARY_SUPPLEMENT: Beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Angioplasty Versus Primary Stenting for the Treatment of Femoropopliteal Artery Chronic Total Occlusions
Status: UNKNOWN
Conditions: Chronic Total Occlusion of Artery of the Extremities
Interventions: DEVICE: Balloon angioplasty|DEVICE: Primary stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COlchicine Improve EnDothElial Function in Non ST Elevation Myocardial Infarction Patients
Status: WITHDRAWN
Conditions: NSTEMI
Interventions: DRUG: Colchicine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants
Status: COMPLETED
Conditions: Healthy|Obese|Overweight
Interventions: DRUG: Orforglipron|DRUG: Simvastatin|DRUG: Digoxin|DRUG: Rosuvastatin|DRUG: Acetaminophen|DRUG: Midazolam|DRUG: Sodium Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amniotic Membrane for Recurrent Macular Hole
Status: UNKNOWN
Conditions: Macula Hole|Retinal Detachment|Myopic Macular Degeneration
Interventions: PROCEDURE: Recurrent opened macular hole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab+Ipilimumab+RT in MSS mCRC
Status: UNKNOWN
Conditions: Metastatic Microsatellite Stable Colorectal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Endotracheal Suction on the Occurrence of Meconium Aspiration Syndrome in Non-vigorous Meconium Stained Babies
Status: COMPLETED
Conditions: Meconium Aspiration Syndrome
Interventions: OTHER: No endotracheal suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Correlation of Pelvic Asymmetry and Joint Movement During Gait in Children With Cerebral Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Correlation of Pelvic Asymmetry and Joint Movement During Gait in Children With Cerebral Palsy
Interventions: DEVICE: three dimensional formetric system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Failure
Interventions: PROCEDURE: continuous, mechanical ventilatory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION