pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dasatinib in Treating Patients With Relapsed Small Cell Lung Cancer
Status: COMPLETED
Conditions: Extensive Stage Small Cell Lung Cancer|Limited Stage Small Cell Lung Cancer|Recurrent Small Cell Lung Cancer
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Dex-methylphenidate Extended Release in Children (6-12 Years) With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Dex-methylphenidate hydrochloride extended-release (Focalin XR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is There Any Correlation Between Plasmatic Zonulin and Expression of Intestinal Tight Junction Proteins in IBS Patients?
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: PROCEDURE: colonoscopy with biopsies in the left colon to assess intestinal permeability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Phase I/II Study of Retroviral-Mediated Transfer of Iduronate-2-Sulfatase Gene Into Lymphocytes of Patients With Mucopolysaccharidosis II (Mild Hunter Syndrome)
Status: COMPLETED
Conditions: Mucopolysaccharidosis II
Interventions: GENETIC: lymphocyte gene therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Migraine Inducing Effect of Levcromakalim in Patients With Migraine With Aura
Status: COMPLETED
Conditions: Headache, Migraine|Aura
Interventions: DRUG: Levcromakalim|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combined Intra-articular Shoulder Injection and Stellate Ganglion Block in Chronic Post-mastectomy Shoulder Pain
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: COMBINATION_PRODUCT: Platelet rich plasma|DRUG: ketamine and bupivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment for Long-Term Cardiovascular Impairment Associated With Trastuzumab Cardiotoxicity in HER2-Positive Breast Cancer Survivors
Status: COMPLETED
Conditions: Trastuzumab Cardiotoxicity|HER2-Positive Breast Cancer Survivors
Interventions: DEVICE: 2D Echocardiogram|DEVICE: Cardiopulmonary exercise testing and post-CPET cardiac function
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Remote Physiological Monitoring Program of Children With Heart Disease
Status: RECRUITING
Conditions: Pediatric ALL|Congenital Heart Disease|Single-ventricle|Biventricular Congestive Heart Failure|Heart Failure|Heart Failure，Congestive|Transplant; Failure, Heart
Interventions: DEVICE: Remote physiological monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Carriere Motion Appliance* Versus In-office Sectional Appliance
Status: TERMINATED
Conditions: Angle Class 2 Malocclusion
Interventions: OTHER: In-office fabricated appliance|DEVICE: Carriere Motion Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hollings Cancer Center Varenicline Sampling Study
Status: COMPLETED
Conditions: Smoking|Smoking Cessation|Smoking, Tobacco|Smoking, Cigarette
Interventions: DRUG: Varenicline 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bone Marrow Cells With Core Decompression for AVN Treatment
Status: COMPLETED
Conditions: Avascular Necrosis of the Femoral Head
Interventions: PROCEDURE: core decompression with local bone marrow mononuclear cells injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Digital Intervention to Increase COVID-19 Vaccination Among Individuals With Anxiety or Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Misinformation|Vaccine Hesitancy|Anxiety|Depression|COVID-19
Interventions: BEHAVIORAL: Attitudinal inoculation|BEHAVIORAL: Cognitive-behavioral therapy-informed intervention|BEHAVIORAL: Conventional public health messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hybrid Revascularisation by Combined Coronary Artery Bypass Graft (CABG) and PCI in Multivessel Coronary Disease
Status: TERMINATED
Conditions: Coronary Artery Disease (CAD)
Interventions: PROCEDURE: LIMA-LAD surgical revascularization|PROCEDURE: PCI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Innovative Silicone Wound Dressing for the Management of Atrophic Vaginitis
Status: COMPLETED
Conditions: Atrophic Vaginitis
Interventions: DEVICE: Film forming silicone gel (7-0940)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cannabinoids to Placebo in Management of TMJ Pain and Myofascial Pain in the TMJ Region
Status: COMPLETED
Conditions: TMJ Disorder|Myofacial Pain|TMD
Interventions: OTHER: CBD Oil|OTHER: Hemp Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Substudy 02B: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With First Line (1L) Advanced Melanoma (MK-3475-02B/KEYMAKER-U02)
Status: RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Vibostolimab|BIOLOGICAL: Pembrolizumab/Quavonlimab|DRUG: Lenvatinib|BIOLOGICAL: Favezelimab/Pembrolizumab|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
Status: RECRUITING
Conditions: Acute Biphenotypic Leukemia|Acute Leukemia|Acute Leukemia of Ambiguous Lineage|Acute Lymphoblastic Leukemia|Acute Undifferentiated Leukemia|Allogeneic Hematopoietic Stem Cell Transplantation Recipient|Blastic Plasmacytoid Dendritic Cell Neoplasm|Blasts Under 25 Percent of Bone Marrow Nucleated Cells|Blasts Under 5 Percent of Bone Marrow Nucleated Cells|Mixed Phenotype Acute Leukemia|Myelodysplastic Syndrome With Excess Blasts-1|Myelodysplastic Syndrome/Acute Myeloid Leukemia
Interventions: RADIATION: Total-Body Irradiation|DRUG: Thiotepa|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Busulfan|PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Tacrolimus|DRUG: Methotrexate|PROCEDURE: Naive T Cell-Depleted Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of Recombinant COVID-19 Vaccine Betuvax-CoV-2
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Betuvax-CoV-2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravaginal Isosorbide Mononitrate in Addition to Misoprostol Versus Misoprostol Only for Induction of Labor
Status: UNKNOWN
Conditions: Induction of Labor
Interventions: DRUG: Isosorbide Mononitrate 40 MG to study group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in Infants and Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV ΔNS2 Δ1313 I1314L Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mesalazine and/or Lactobacillus Casei in the Diverticular Disease of the Colon
Status: COMPLETED
Conditions: Diverticular Disease of the Colon
Interventions: DRUG: Mesalazine plus Lactobacillus casei|DRUG: Mesalazine placebo plus Lactobacillus casei placebo|DRUG: Mesalazine 800 mg|DRUG: Lactobacillus casei
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea in Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DIAGNOSTIC_TEST: polysomnography and oxygen saturation exam|BIOLOGICAL: calculation of VOC frequency between the first polysomnography and the end of the first year of continuous positive airway pressure treatment|BIOLOGICAL: Blood samples|OTHER: Physiological measurements|OTHER: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of an Intervention Combining Self-care and Hypnosis on the Well-being of Cancer Patients and Their Partners
Status: COMPLETED
Conditions: Non-Metastatic Neoplasm
Interventions: BEHAVIORAL: Self-hypnosis + Self-care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Rectal Adenocarcinoma
Interventions: DRUG: APX005M, mFOLFOX, and Radiation Therapy 5Gy x 5 days|DRUG: mFOLFOX and Radiation Therapy 5Gy x 5 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Anakinra in Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Anakinra 100Mg/0.67Ml Inj Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SBRT in the Reirradiation for Ultra-central Thoracic Malignant Tumors
Status: RECRUITING
Conditions: Stereotactic Body Radiation Therapy|Irradiation; Reaction|Thoracic Tumor|Recurrent Cancer
Interventions: RADIATION: stereotacitic body radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Olmesartan Medoxomil Tablet Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Torrent's Olmesartan Medoxomil Tablets 40 mg|DRUG: Daiichi Sankyo Inc's Benicar Tablets 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combining a Neuromuscular Electrical Stimulation Intervention With Nutritional Support in Deconditioned Patients With Advanced Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Cancer Digestive
Interventions: OTHER: NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of ATG-F on Engraftment, Graft Versus Host Disease (GVHD) and Graft Versus Leukemia (GVL) Effect in Haplo-identical SCT
Status: TERMINATED
Conditions: Allogeneic Haplo-Stem Cell Transplatation (SCT)|Graft Versus Host Disease
Interventions: DRUG: ATG-F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loop Gain in the Reversion of OSA Treated by Either CPAP or Cardiac Valve Replacement
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea of Adult|Heart Valve Diseases
Interventions: DEVICE: continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery
Status: COMPLETED
Conditions: Kidney Failure, Acute|Renal Replacement Therapy
Interventions: DRUG: Sodium bicarbonate|OTHER: Normal saline|OTHER: Bicarbonate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Incomplete Spinal Cord Injury
Interventions: DEVICE: Anodal tsDCS|DEVICE: Cathodal tsDCS|DEVICE: Sham tsDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Lightweight Ambulatory Oxygen Systems for Individuals With Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: E-Cylinder|DEVICE: Lightweight Cylinder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Vitamin D-fortified Bread in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: fortified bread|DIETARY_SUPPLEMENT: supplement|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Magnetic Stimulation Theta Burst (TMS), Depression and Smoking.
Status: RECRUITING
Conditions: Major Depressive Disorder|Smoking Reduction
Interventions: DEVICE: Theta Burst Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Arm Pilot Study of Pulsed Field Ablation in the Treatment of Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Catheter ablation to treat paroxysmal atrial fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre Diabetes
Interventions: OTHER: Hyperinsulemic euglycemic clamp|PROCEDURE: Muscle Biopsy|DIETARY_SUPPLEMENT: Oral abscisic acid (ABA)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Maintenance NeuroStar Transcranial Magnetic Stimulation (TMS) in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: NeuroStar TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatitis B Vaccination in HIV-infected Adults With Low CD4 Cell Counts
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Recombinant Hepatitis B vaccine [(CIGB) La Habana, Cuba]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of the Full Face Applications of Variable Doses of a Commercial Botulinum Toxin Type a (Dysport®)
Status: COMPLETED
Conditions: Sun-induced Wrinkles
Interventions: DRUG: Botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS Combined With Therapeutic Exercise in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Real tDCS|DEVICE: Sham tDCS|DEVICE: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-2225 / ACE-1334 in Participants With Systemic Sclerosis With and Without Interstitial Lung Disease (MK-2225-002)
Status: TERMINATED
Conditions: Systemic Sclerosis With and Without Interstitial Lung Disease
Interventions: BIOLOGICAL: MK-2225|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilation Imaging to Improve the Quality of Life for Patients With Lung Cancer Treated With Radiation Therapy
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Healthy lung sparing treatment plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Acute Lung Injury Ventilator Evaluation (ALIVE)
Status: TERMINATED
Conditions: Acute Lung Injury|Adult Respiratory Distress Syndrome
Interventions: OTHER: Low-tidal-volume ventilation|OTHER: Airway Pressure Release Ventilation (APRV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Fecal Immunochemical Test|OTHER: Interview|BEHAVIORAL: Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People
Status: UNKNOWN
Conditions: Diabetes Mellitus|Gastroparesis
Interventions: DRUG: Lixisenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine
Status: COMPLETED
Conditions: Rotavirus Vaccine
Interventions: BIOLOGICAL: RV3-BB|BIOLOGICAL: Trivalent P2-VP8|BIOLOGICAL: Rotarix|BIOLOGICAL: RV3-BB birth dose|BIOLOGICAL: Trivalent P2-VP8 Booster dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Omadacycline vs. Placebo in Adults With NTM Pulmonary Disease Caused by Mycobacterium Abscessus Complex (MABc)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mycobacterium Infections, Nontuberculous|Mycobacterium Abscessus Infection|Nontuberculous Mycobacterial Lung Disease|Nontuberculous Mycobacterial Pulmonary Infection
Interventions: DRUG: Omadacycline Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Switching From Regimens of ABC/3TC + a 3rd Agent to E/C/F/TAF Fixed-Dose Combination (FDC) in Virologically-Suppressed HIV 1 Infected Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: E/C/F/TAF|DRUG: ABC/3TC|DRUG: Third Antiretroviral Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography (PET) With 3,4-dihydroxy-6-18F-fluoro-L-enylalanine (18F-FDOPA) Study
Status: COMPLETED
Conditions: Cancer (High-grace Glioma)
Interventions: PROCEDURE: Surgical neuronavigation with 18F-DOPA PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of P276-00 in Combination With Radiation in Subjects With Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: P276-00|RADIATION: External beam radiotherapy (EBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interscalene Block Versus Erector Spinae Plane Block for Shoulder Arthroscopy Anesthesia
Status: RECRUITING
Conditions: Interscalene Block|Erector Spinae Plane Block|Arthroscopy
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Interscalene brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and Efficacy of the CardioPulseTM PuLsed fiEld Ablation SystEm in Patients With Paroxysmal Atrial Fibrillation (PLEASE-AF Study)
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: CardioPulsesTM pulsed field ablation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring
Status: RECRUITING
Conditions: Dupuytren Contracture
Interventions: PROCEDURE: Pretendinous cord excision|PROCEDURE: Division/manipulation of the cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetic Retinopathy Vitrectomy Study (DRVS)
Status: COMPLETED
Conditions: Diabetic Retinopathy|Retinal Detachment|Vitreous Hemorrhage
Interventions: PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Effectiveness of the Investigational Product in Improvement of the Appearance of Wrinkles and General Aspect of the Skin
Status: COMPLETED
Conditions: Skin Aging
Interventions: DEVICE: MEDGEL ANTIAGE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Study to Identify Sentinel Lymph Nodes in Women With Stage I or Stage II Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: patent blue V dye|PROCEDURE: lymphangiography|PROCEDURE: radionuclide imaging|PROCEDURE: sentinel lymph node biopsy|RADIATION: technetium Tc 99m sulfur colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Investigate How Solifenacin Fluid is Taken up, How Long it Stays in the Body and How Effective and Safe it is in Treating Children Aged From 6 Months to Less Than 5 Years With Symptoms of Neurogenic Detrusor Overactivity (NDO)
Status: COMPLETED
Conditions: Neurogenic Detrusor Overactivity|Pediatric
Interventions: DRUG: Solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigid Thoracoscopy Versus CT-Guided Pleural Needle Biopsy
Status: COMPLETED
Conditions: Pleural Effusion|Pleural Diseases
Interventions: PROCEDURE: Ct-guided pleural needle biopsy|PROCEDURE: Thoracoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Evaluate the Immunogenicity and Safety of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) in Adults Aged 18 to 55 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: batch 1 of Group ACYW135 Meningococcal Conjugate Vaccine (CRM197) (MCV4)|BIOLOGICAL: batch 2 of MCV4|BIOLOGICAL: batch 3 of MCV4|BIOLOGICAL: Meningococcal (Groups A, C, Y, and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Six-month Performance of Meniscal Wall Infiltration Under Ultrasound to Treat Stable Degenerative Meniscal Injuries.
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Injection of corticosteroids (Diprostène®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Doppler Sonography, MR Venography, Plethysmography for the Diagnosis of CCSVI
Status: COMPLETED
Conditions: Chronic Cerebrospinal Venous Insufficiency
Interventions: OTHER: Doppler sonography of internal jugular veins|OTHER: Magnetic resonance venography of internal jugular veins|OTHER: Air-plethysmography of the neck|OTHER: Catheter venography of internal jugular veins
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a Multicomponent Exercise Program With Virtual Reality (MEP-VR) vs Standard Approaches on Functional and Cognitive Domains in Hospitalized Geriatric Patients: Study Protocol for a Randomized Controlled Trial.
Status: RECRUITING
Conditions: Hospital Acquired Condition|Frailty
Interventions: BEHAVIORAL: MEP-only group|BEHAVIORAL: MEP-VR group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Molecular Taxonomy of Surgically-harvested Ocular Tissues Defined by Single-cell Transcriptomics
Status: UNKNOWN
Conditions: Diabetic Retinopathy|Proliferative Vitreoretinopathy|Pterygium|Glaucoma
Interventions: PROCEDURE: ocular surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of NI-1801 in Patients With Mesothelin Expressing Solid Cancers
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Triple Negative Breast Cancer|Non-squamous Non-small-cell Lung Cancer
Interventions: BIOLOGICAL: NI-1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RosaC-RF : Bipolar Radiofrequency vs Doxycycline in Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DEVICE: Radiofrequence|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole
Status: UNKNOWN
Conditions: Hydatidiform Mole
Interventions: PROCEDURE: Suction and evacuation|PROCEDURE: Suction and evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change
Status: COMPLETED
Conditions: Alcohol Use, Underage|Alcohol Problem Drinking|Substance Use
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention|BEHAVIORAL: Control (CTL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Body Versus Machine: Deep Breathing Versus Vagus Stimulation for the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Chronic Widespread Pain|Fibromyalgia
Interventions: DEVICE: Transcutaneous Vagal Nerve Stimulation (tVNS)|OTHER: Motivational nondirective resonance breathing (MNRB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Irinotecan -Eluting LC Bead-M1 (DEBIRI-M1) for Patients With Liver Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: DEBIRI|DEVICE: LC Bead M1|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrocortisone for Prevention of Septic Shock
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: Placebo|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate FN-1501 Monotherapy in Patients With Advanced Solid Tumors and R/R AML
Status: TERMINATED
Conditions: Advanced Cancer|Solid Tumors|Acute Myeloid Leukemia Refractory|Acute Myeloid Leukemia, in Relapse
Interventions: DRUG: FN-1501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects
Status: COMPLETED
Conditions: Severe Asthma
Interventions: DRUG: Mepolizumab Injection (BAT2606 Injection)|DRUG: Mepolizumab Injection (EU-licensed Nucala)|DRUG: Mepolizumab Injection (US-licensed Nucala)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Didactic Intervention in Anticoagulated Patients (TAOPE Study)
Status: UNKNOWN
Conditions: Health Education|Patient Education as Topic|Blood Coagulation Tests
Interventions: BEHAVIORAL: Patient education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Observational Prospective Study on Patients With Symptomatic Uterine Fibroids Treated With VizAblate® Intrauterine-ultrasound Guided RF Ablation
Status: TERMINATED
Conditions: Menorrhagia|Leiomyoma|Uterine Fibroids|Uterine Fibroma|Uterine Neoplasms
Interventions: DEVICE: VizAblate System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IV Contrast-Enhanced Cone Beam Computed Tomography (CBCT) in Radiotherapy
Status: TERMINATED
Conditions: Pelvic Cancer|Abdominal Cancer
Interventions: DRUG: Omnipaque 300mg/mL Solution for Injection|RADIATION: Cone Beam CT|RADIATION: Radiation Therapy|DRUG: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Status: COMPLETED
Conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma
Interventions: DRUG: Daratumumab|DRUG: Vincristine|DRUG: Prednisone|DRUG: Doxorubicin|BIOLOGICAL: Peg-asparaginase|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: 6-mercaptopurine|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Different Puncture Techniques in EBUS-TBNA
Status: RECRUITING
Conditions: Lung Cancer|Sarcoidosis|Tuberculosis
Interventions: PROCEDURE: Endobronchial ultrasound-guided transbronchial needle Slow-pull capillary sampling|PROCEDURE: Endobronchial ultrasound-guided transbronchial needle aspiration|PROCEDURE: Endobronchial ultrasound-guided transbronchial needle capillary sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Performance of Thermoviscous Bulk Fill Resin Composites in Comparison to Conventional Packable Bulk Fills
Status: UNKNOWN
Conditions: Caries,Dental
Interventions: OTHER: thermoviscous bulkfill composite (Viscalor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIMOX - Induction of Oxidative Stress
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Safety & Immunogenicity of GSK Biologicals' DTPa/Hib Vaccine vs Separate Administration of DTPa and Hib.
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Acellular Pertussis
Interventions: BIOLOGICAL: Infanrix™/Hib|BIOLOGICAL: Infanrix|BIOLOGICAL: Hiberix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open Study to Evaluate the Efficacy, Safety of Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Clevudine 30mg|DRUG: Clevudine 20mg+Adefovir dipivoxil 10mg|DRUG: Clevudine 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Optimark (Gadoversetamide) in Pediatric Patients
Status: COMPLETED
Conditions: Pathological Processes
Interventions: PROCEDURE: MRI|PROCEDURE: MRI|DRUG: Gadoversetamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Observational Study With Metronomic Oral Vinorelbine in Elderly Patients With Locally Advanced / Metastatic Non-small-cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Locally Advanced/ Metastatic NSCLC
Interventions: DRUG: Vinorelbine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patient-reported Experiences and Quality of Life Outcomes in the TB-PRACTECAL Clinical Trial
Status: COMPLETED
Conditions: Multidrug Resistant Tuberculosis
Interventions: DRUG: Bedaquiline|DRUG: Pretomanid|DRUG: Moxifloxacin|DRUG: Linezolid|DRUG: Clofazimine|DRUG: Directly observed therapy (DOT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating a Pharmacokinetic Drug Interaction Between LGEV1801 and LGEV1802
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Valsartan|DRUG: Ezetimibe/Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLeeding Events and Maintenance DoSe of PraSugrel
Status: TERMINATED
Conditions: Adverse Reaction to Antiplatelet Agent|Acute Coronary Syndrome
Interventions: DRUG: Prasugrel dose 5 mg/day|DRUG: Prasugrel dose 10 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery
Status: COMPLETED
Conditions: Diabetes|Hyperglycemia|Surgical Site Infection
Interventions: DRUG: Tight Glycemic|DRUG: Conventional Glycemic|DRUG: Standard Glycemic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevalence of Thyroid Function Abnormalities in HIV-infected Patients
Status: UNKNOWN
Conditions: Thyroid|HIV Infections
Interventions: OTHER: Assay of TSH, FT3 and FT4 by immuno-radiometric method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Perioperative Analgesia in Neonates
Interventions: PROCEDURE: the standard procedure - without regional anaesthesia|PROCEDURE: infraorbital peripheral blockade with or without nasal peripheral blockade according to the preference of the anesthesiologist and surgeon
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect on paO2 of Adding an Aerosol Mask Above the Nasal Canulas
Status: UNKNOWN
Conditions: Hypoxemic Respiratory Failure|Emergencies|Covid19
Interventions: DEVICE: Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DNA Methylation Testing for the Screening of Uterine Cervical Lesion
Status: UNKNOWN
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia|DNA Methylation|High-risk Human Papillomavirus|Cytology
Interventions: DIAGNOSTIC_TEST: Host DNA methylation testing|DIAGNOSTIC_TEST: Cervical cytology and/or high-risk human papillomavirus assays
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Critical Errors, Overall Errors, Training/Teaching Time, and Preference Attributes of the ELLIPTA Versus BREEZHALER Dry Powder Inhalers (DPIs) in Adult Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: ELLIPTA|DEVICE: BREEZHALER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF
Status: COMPLETED
Conditions: Acute-On-Chronic Liver Failure
Interventions: BIOLOGICAL: HepaStem
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG-rhG-CSF Compared With rhG-CSF in Lymphoma Patients After Autologous Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: PEG-rhG-CSF|DRUG: rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Single Dose of a Polyphenol-enriched Brown Seaweed Powder in Human
Status: COMPLETED
Conditions: Glycemic Index
Interventions: DIETARY_SUPPLEMENT: Brown seaweed powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Blueberries on Vascular Function in Healthy Men
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Blueberries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Transcutaneous Vagal Stimulation (TVS) on Endothelial Function in PAD
Status: COMPLETED
Conditions: Peripheral Artery Disease|Endothelial Dysfunction|Autonomic Imbalance
Interventions: DEVICE: TVS|DEVICE: Sham TVS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Multi-tined Cannula Versus a Conventional Cannula for Cervical Medial Branch Radiofrequency Ablation in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Radiofrequency Ablation|Facet Joint Pain
Interventions: DEVICE: Radiofrequency ablation of cervical medial branches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Bepotastine besilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Apnea Testing in CHildren Trial
Status: RECRUITING
Conditions: Sleep Apnea, Obstructive|Sleep Disorder|Sleep Apnea Syndromes|Sleep Disturbance
Interventions: DIAGNOSTIC_TEST: Home sleep apnea test|DIAGNOSTIC_TEST: In-lab polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Turmeric Gel as Alternative Non-vital Pulpotomy Medicament in Primary Teeth
Status: COMPLETED
Conditions: Non-Vital Tooth
Interventions: DRUG: Turmeric Gel|DRUG: Formocresol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Bone Marrow Stem Cell Transplantation in Liver Failure
Status: UNKNOWN
Conditions: Liver Failure
Interventions: PROCEDURE: Allogenic bone marrow stem cells transplantation|DRUG: Conserved therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instrumentation Time Efficiency and Histologically the Debriding Efficacy.
Status: UNKNOWN
Conditions: Necrosis
Interventions: PROCEDURE: Clean and shape Control group|PROCEDURE: Cleand and shape Group 1|PROCEDURE: Clean and shape Group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Agility Training for Older Adults to Improve Fall Risk Factors
Status: RECRUITING
Conditions: Age-Related Loss of Skeletal Muscle Mass|Aging|Sarcopenia|Cognitive Decline
Interventions: BEHAVIORAL: Agility training|BEHAVIORAL: Exercise recommendations|BEHAVIORAL: Exercise diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AB521|DRUG: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Peanut Consumption on Brain Function
Status: COMPLETED
Conditions: Brain Vascular Function|Cerebral Blood Flow|Brain Insulin Sensitivity|Cognitive Performance
Interventions: DIETARY_SUPPLEMENT: Skin roasted peanuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capsula Closure vs. Non-Capsula Closure: Hip Arthroscopy in Danish Patients With Femoroacetabular Impingement (FAI)
Status: RECRUITING
Conditions: Hip Injuries
Interventions: PROCEDURE: Capsula Closure|PROCEDURE: Non-Capsula Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevalence of OSA in COPD and the Clinical Impact of OSA Diagnosis and Treatment
Status: UNKNOWN
Conditions: Prevalence of OSA in Patients Hospitalized With COPD Exacerbation
Interventions: DEVICE: WatchPAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study to Evaluate Safety and Immunogenicity of Bacillus Calmette-Guerin (BCG) Delivery Via Novel Micronjet600 Device Compared to Those Via Conventional Needle
Status: COMPLETED
Conditions: Tuberculosis|BCG Vaccination
Interventions: DEVICE: BCG vaccination with MicronJet600|DEVICE: BCG vaccination with conventional needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mycose AdminiStration for HealIng Alzheimer NEuropathy (MASHIANE)
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DRUG: Trehalose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Relugolix/E2/NETA FDC|DRUG: Relugolix|DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled, Double-Blind, Study to Determine the Safety and Efficacy of SDX in Patients With IH
Status: COMPLETED
Conditions: Idiopathic Hypersomnia
Interventions: DRUG: Serdexmethylphenidate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics, of VX-993
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-993|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Knowledge, Attitudes and Practices of Paediatric Cardiologists About Cardiac Rehabilitation in Children With Congenital Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Physician's Role
Interventions: OTHER: Questionnaire on knowledge, attitudes and practices of paediatric cardiologists about cardiac rehabilitation in children with congenital heart disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p