pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hot Nasal Packing With Hot Saline Irrigation for Hemostasis After Adenoidectomy
Status: UNKNOWN
Conditions: Hemostasis After Adenoidectomy
Interventions: PROCEDURE: Hot nasal packing with hot saline irrigation for hemostasis after adenoidectomy|PROCEDURE: Cold nasal packing with cold saline irrigation for hemostasis after adenoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: cisplatin|DRUG: lomustine|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Assess the Effectiveness of Benzocaine in NRL Condoms in Healthy Adult Men Who Feel They Ejaculate Too Quickly During Vaginal Sex
Status: RECRUITING
Conditions: Ejaculation Delayed
Interventions: DEVICE: Test condom A (NRL condom with 5% benzocaine paste)|DEVICE: Test condom B (NRL condom with 3% benzocaine paste)|DEVICE: Control NRL condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Two-Session Couples Class to Improve Relationship Health
Status: TERMINATED
Conditions: Stress
Interventions: BEHAVIORAL: Mindfulness Compassion (MC)|BEHAVIORAL: Mindfulness Gratitude (MG)|BEHAVIORAL: Mindfulness Value-Based Living (MV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns
Status: COMPLETED
Conditions: Smoking|Tobacco Use
Interventions: BEHAVIORAL: Low Power|BEHAVIORAL: High Power|BEHAVIORAL: Low Concentration|BEHAVIORAL: High Concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding
Status: COMPLETED
Conditions: Bleeding|Blood Loss, Surgical|Cardiovascular Surgical Procedures|Prothrombin Complex Concentrates|Fresh Frozen Plasma
Interventions: DRUG: Prothrombin complex concentrate (Human)|BIOLOGICAL: Fresh frozen plasma (FFP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Intensive Education and Coaching on Compliance for Oral Ganciclovir in the Prophylaxis of CMV: an Open Randomised Trial
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BEHAVIORAL: instructions and coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Clinical Trial to Evaluate: Part A. The Safety of MTP-PE/MF59 Adjuvant Emulsion. Part B. The Safety and Immunogenicity of Env 2-3, a Yeast Derived Recombinant Envelope Protein of Human Immunodeficiency Virus-1, in Combination With MTP-PE/MF59
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: MTP-PE/MF59|BIOLOGICAL: Env 2-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness
Status: COMPLETED
Conditions: Primary Biliary Cholangitis|Liver Stiffness
Interventions: DRUG: Setanaxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial for Extraction of Difficult Bile Duct Stones
Status: COMPLETED
Conditions: Common Bile Duct Stones
Interventions: PROCEDURE: Single-operator cholangioscopy-guided laser lithotripsy|PROCEDURE: Balloon Sphincteroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Two Manipulative Protocols in Treatment of Hip Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Hip
Interventions: PROCEDURE: manual or manipulative therapy|PROCEDURE: Manual / Manipulative Therapy|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Fractional Bi-Polar Radio-Frequency for Symptoms of Vulvovaginal Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaginal Atrophy
Interventions: DEVICE: MorpheusV Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XZP-5809-TT1 Tablets in Patients With T790M Mutation-positive Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: XZP-5809-TT1 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of an Adaptive Treatment for Weight Loss in People With Prediabetes
Status: COMPLETED
Conditions: PreDiabetes|Obesity
Interventions: BEHAVIORAL: High Carbohydrate Diet|BEHAVIORAL: Reduced Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage
Status: COMPLETED
Conditions: Intracranial Hemorrhage
Interventions: DEVICE: Apollo Device|DEVICE: Artemis Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of Pregnant Women After a Mass Vaccination of Oral Cholera Vaccine (ShancholTM) in Nsanje Malawi
Status: TERMINATED
Conditions: Miscarriage|Stillbirth|Cholera
Interventions: BIOLOGICAL: Shanchol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Levocarnitine Supplementation for the Management of Fatigue in Levothyroxine-Treated Hypothyroid Patients
Status: UNKNOWN
Conditions: Patient Compliance
Interventions: DRUG: Levocarnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of High Tone Power Therapy on Neurophysiological Measures and Function Outcome in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy Peripheral
Interventions: DEVICE: High tone power therapy|OTHER: Selected Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅰa Study of Remimazolam Tosylate in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Remimazolam Tosylate|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Periodontal Disease in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Periodontitis
Interventions: PROCEDURE: supra/sub gingival root surface debridement|PROCEDURE: supra-gingival scaling and polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study With Andes-1537 in Patients With Specific Types of Advanced Solid Tumor
Status: COMPLETED
Conditions: Tumor, Solid|Gall Bladder Cancer|Cervical Cancer|Gastric Cancer|Pancreatic Cancer|Colorectal Cancer
Interventions: DRUG: Andes-1537 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine, Cisplatin, Plus Lenalidomide as First-line Therapy for Patients With Metastatic Urothelial Carcinoma
Status: TERMINATED
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplantation Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells With Intensive Atorvastatin in AMI Patients
Status: UNKNOWN
Conditions: Myocardial Infarction|Stem Cell Transplantation|Angioplasty, Transluminal, Percutaneous Coronary
Interventions: DRUG: Atorvastatin|DRUG: Intensive Atorvastatin|DRUG: Low dose BMMSC|DRUG: Middle dose BMMSC|DRUG: High dose BMMSC|DRUG: Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of GABAA Receptor Modulation by AP-325 on Insulin Secretion in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Type2 Diabetes
Interventions: DRUG: AP-325|DRUG: Placebo matching AP-325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib and Serplulimab Combined With AG Regimen Compare With AG Regimen as Conversion Therapy for Patients With Locally Advanced Pancreatic Cancer (SAGE)
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Pancreatic Cancer
Interventions: DRUG: Surufatinib + Serplulimab+Albumin-paclitaxel + Gemcitabine|DRUG: Albumin-paclitaxel + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Language Development|Neurocognitive Disorders|Child Language
Interventions: DEVICE: EEG-HR|DIAGNOSTIC_TEST: ADI-R|DIAGNOSTIC_TEST: ADOS-2|DIAGNOSTIC_TEST: IDE|DIAGNOSTIC_TEST: MSEL|DIAGNOSTIC_TEST: Dunn
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Acarbose+Saxagliptin Compared With Metformin+Saxagliptin in Patients With Type 2 Diabetes
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Acarbose|DRUG: Metformin|DRUG: Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pelvic Floor Exercise on Urinary Incontinence and Quality of Sex Life
Status: COMPLETED
Conditions: Pelvic Floor Muscle Weakness|Urinary Incontinence
Interventions: OTHER: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of the Manual Exploration as a Supplement to the Coelioscopy in the Evaluation of the Resectability of Peritoneal Carcinosis
Status: COMPLETED
Conditions: Ovarian Cancer With Peritoneal Carcinosis
Interventions: PROCEDURE: GelPort|PROCEDURE: laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Akt Inhibitor MK2206 in Treating Patients With Progressive, Recurrent, or Metastatic Adenoid Cyst Carcinoma
Status: COMPLETED
Conditions: Recurrent Oral Cavity Adenoid Cystic Carcinoma|Recurrent Salivary Gland Carcinoma|Salivary Gland Adenoid Cystic Carcinoma|Stage IVA Major Salivary Gland Cancer AJCC v7|Stage IVA Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7|Stage IVB Major Salivary Gland Cancer AJCC v7|Stage IVB Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7|Stage IVC Major Salivary Gland Cancer AJCC v7|Stage IVC Oral Cavity Adenoid Cystic Carcinoma AJCC v6 and v7
Interventions: DRUG: Akt Inhibitor MK2206|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differences in Preparation for Small Bowel Capsule Endoscopy
Status: UNKNOWN
Conditions: Capsule Endoscopy|Inflammatory Bowel Diseases|Celiac Disease
Interventions: DRUG: Klean Prep|OTHER: Clear liquids only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy, Pharmacodynamics, Safety, and Immunogenicity of FKS518 in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: FKS518|DRUG: US-licensed Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Attenuates Inflammation in Human Cerebral Aneurysms
Status: COMPLETED
Conditions: The Focus of the Study is to Monitor MRI Signal Changes and Inflammatory Biomarkers With Use of Aspirin in Patients With Unruptured Cerebral Aneurysm
Interventions: DRUG: aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of a Comprehensive Health Coaching Program in Advanced Chronic Obstructive Pulmonary Disease.
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease Severe|Chronic Obstructive Pulmonary Disease End Stage
Interventions: BEHAVIORAL: Comprehensive Health Coaching Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Solifenacin and Mirabegron in Treatment of Overactive Bladder Symptoms in Men After TURP
Status: UNKNOWN
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: Solifenacin 5Mg|DRUG: Mirabegron 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravascular Imaging- Versus Angiography-Guided Percutaneous Coronary Intervention For Complex Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis
Interventions: PROCEDURE: Percutaneous coronary intervention for complex lesion|DEVICE: Drug-eluting stent|DEVICE: Intravascular imaging (IVUS or OCT)|DEVICE: Drug-coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D
Status: RECRUITING
Conditions: Hypoglycemia|Type 1 Diabetes
Interventions: DRUG: Dasiglucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bismuth Subsalicylate's Role in the Prevention of Travelers' Diarrhea
Status: TERMINATED
Conditions: Diarrhea Travelers|Antibiotic Resistant Infection
Interventions: DRUG: Bismuth subsalicylate|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of ALRN-6924 in Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: ALRN-6924|DRUG: ALRN-6924 in combination with cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone and Misoprostol for Fetal Demise
Status: COMPLETED
Conditions: Anembryonic Pregnancy|Gestation Abnormality|Intrauterine Fetal Demise Term
Interventions: DRUG: mifepristone/misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of İnferior Vena Cava Diameter and Collapsibility Index on Fluid Management
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypovolemia
Interventions: PROCEDURE: peroperative inferior vena cava measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Nepafenac Versus Ketorolac Eye Drops in Prevention of Intraoperative Miosis During Cataract Surgery
Status: UNKNOWN
Conditions: Cataract|Miosis
Interventions: DRUG: Ketorolac Ophthalmic|DRUG: Nepafenac Ophthalmic|DRUG: Cyclopentolate Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Selected Factors on the Cardiovascular System in Chronic Kidney Disease
Status: COMPLETED
Conditions: Atherosclerosis of Artery|Inflammation|Chronic Kidney Diseases|Dialysis; Complications|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: laboratory parameters - complete blood count|OTHER: body mass index (BMI) [kg/m^2] calculation|DIAGNOSTIC_TEST: selected parameters of oxidative stress (1)|DIAGNOSTIC_TEST: metalloproteinases|DIAGNOSTIC_TEST: parameters of lipids metabolism in the serum|DIAGNOSTIC_TEST: parameters of iron metabolism|DIAGNOSTIC_TEST: selected inflammatory markers|DEVICE: carotid intima-media thickness (IMT)|DEVICE: non-invasive cardiological examinations|DEVICE: vessel stiffness assessment|OTHER: cardiovascular (CV)-related death recording during 2-year follow-up|DIAGNOSTIC_TEST: glucose (Glu)|DIAGNOSTIC_TEST: klotho|DIAGNOSTIC_TEST: fibroblast growth factor 23 (FGF-23)|DIAGNOSTIC_TEST: parameters of calcium and phosphate metabolism|DIAGNOSTIC_TEST: liver enzymes activity assessment|DIAGNOSTIC_TEST: total protein and albumin|DIAGNOSTIC_TEST: creatinine and urea|DIAGNOSTIC_TEST: selected parameters of oxidative stress (2)|DIAGNOSTIC_TEST: selected parameters of oxidative stress (3) sRAGE|DIAGNOSTIC_TEST: selected parameters of oxidative stress (4) MG, CEL, carbamyl protein groups|DIAGNOSTIC_TEST: selected electrolytes assessment|DIAGNOSTIC_TEST: NT-pro-brain natriuretic peptide (NT-proBNP)|OTHER: estimated glomerular filtration rate (eGFR) calculation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Inspiratory Muscle Training on the Functional Gait Performance of Individuals After Stroke
Status: COMPLETED
Conditions: Stroke|Inspiratory Muscle Training|Quality of Life|Gait
Interventions: OTHER: Inspiratory Muscle Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BI 1356 (Linagliptin) in Combination With Metformin and a Sulphonylurea in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: linagliptin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SHARE: Sharing Healthcare Wishes in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Impairment
Interventions: BEHAVIORAL: Sharing Healthcare Wishes in Primary Care (SHARE)|BEHAVIORAL: Minimally Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FP-101 for the Treatment of Hot Flashes in Postmenopausal Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: FP-101|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: Atezolizumab 840 MG in 14 ML Injection|DRUG: Atezolizumab 1200 MG in 20 ML Injection|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide|PROCEDURE: Biopsy Arm A|PROCEDURE: Biopsy Arm B|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury|Knee Injury
Interventions: PROCEDURE: Standard Plyometric Training|PROCEDURE: Plyometric Training with BWS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LAS41003 in the Treatment of Inflammatory Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: LAS41003|DRUG: LAS189961|DRUG: LAS189962
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Long-acting Injectable Medications for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: haloperidol decanoate|DRUG: paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immune Response to Adjuvanted A(H1N1)v Influenza Vaccine in HIV-1 Infected and Immunosuppressed Adult Patients
Status: UNKNOWN
Conditions: HIV-1 Infection|Cancer|Immunosuppression
Interventions: OTHER: serologic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gastrointestinal Endoscopy Artificial Intelligence Cloud Platform in Gastrointestinal Endoscopy Screening
Status: UNKNOWN
Conditions: Diagnoses Disease|Quality Control|Endoscopy|Artificial Intelligence
Interventions: DEVICE: The Artificial intelligence Cloud Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Hormonal Therapy Compared to Neoadjuvant Chemotherapy in Stage IIIB/C and IV Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Aromatase Inhibitors (Arimidex)|DRUG: Tamoxifen|PROCEDURE: SOB|DRUG: FAC|DRUG: Aromatase Inhibitors (Femara)|DRUG: Aromatase Inhibitors (Aromasin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Intervention in COPD Dyads
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Mindfulness-based stress reduction intervention|BEHAVIORAL: Information on stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between AOT and Functional Training on Balance, Mobility and Cognition in Diplegic Cerebral Palsy
Status: RECRUITING
Conditions: Diplegic Cerebral Palsy
Interventions: OTHER: Action Observation Theraoy|OTHER: Functional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stabilized Whole Rice Bran (SWRB) for Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Stabilised Whole Rice Bran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma in Corneal Surface Diseases
Status: NOT_YET_RECRUITING
Conditions: Persistent Corneal Epithelial Defects|Dry Eye
Interventions: DRUG: Autologous platelet rich plasma eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulation-based Education for Managing Stress in ICU Nurses
Status: COMPLETED
Conditions: Professional Stress
Interventions: OTHER: Simulation during the study (5-day specific training with dedicated scenario done by an ICU expert simulation team)|OTHER: questionnaire to define the presence of job strain at 6 months|OTHER: questionnaire to define the presence of job strain at 12 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Safety and Efficacy of the OPTIMIZER® System in Subjects With Moderate-to-Severe Heart Failure: FIX-HF-5C
Status: COMPLETED
Conditions: NYHA Class III Heart Failure|NYHA Class IV Heart Failure
Interventions: DEVICE: Optimizer System|OTHER: No intervention: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of Polymerized, Mannan-Conjugated Dermatophagoides Allergen Extract
Status: NOT_YET_RECRUITING
Conditions: Allergic Rhinitis|Allergic Asthma|Allergic Rhinoconjunctivitis|Allergy to House Dust Mite
Interventions: BIOLOGICAL: 3,000 MM09|BIOLOGICAL: 9,000 MM09|OTHER: Placebo sublingual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
Status: RECRUITING
Conditions: Infertility Primary
Interventions: OTHER: Magenta AI image analysis tool
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Divalproex Extended Release Monotherapy in Ambulatory Bipolar Spectrum Disorder With Moderate-to-Severe Hypomania or Mild Mania
Status: COMPLETED
Conditions: Bipolar Spectrum Disorder With Moderate-to- Severe Hypomania or Mild Mania
Interventions: DRUG: Divalproex|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Acceptability, and Pharmacokinetic (PK) Study of Cabotegravir (CAB) in Healthy Human Immunodeficiency Virus (HIV)-Uninfected Chinese Men
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Oral CAB|DRUG: CAB LA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: LSD|DRUG: Ketanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of an Ultrasonic Denture Hygiene Intervention Program Among Community-dwelling Elders
Status: COMPLETED
Conditions: Denture|Removable Partial Denture|Denture Cleansers|Cetylpyridinium Chloride
Interventions: DEVICE: Ultrasonic cleaning|DEVICE: Ultrasonic cleaning|OTHER: Conventional denture hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T-19 Cells for Patients With CD19+ Relapse/Refractory B-ALL
Status: RECRUITING
Conditions: CD19+ Relapse/Refractory B-ALL
Interventions: BIOLOGICAL: CAR-T-19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Versus Nonselective Alpha-blockade Prior to Pheochromocytoma Resection - Systematic Review and Meta-analysis
Status: COMPLETED
Conditions: Pheochromocytoma
Interventions: DRUG: Selective alpha-1-antagonist|DRUG: Non-selective alpha-1-antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-Calorie Diets on Type 2 Diabetes Remission
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity|Overweight
Interventions: OTHER: Formula diet|OTHER: Food-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3h of PNE on BDNF and Pain Levels
Status: RECRUITING
Conditions: Chronic Pain|Musculoskeletal Pain
Interventions: BEHAVIORAL: Pain neuroscience grupal education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of GLP-1 for Diabetic Bariatric Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide (1 Mg Dose)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Efficacy and Safety Study of AQX-1125 in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: AQX-1125|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: PF-04937319 once-daily|DRUG: PF-04937319 split-dose|DRUG: Sitagliptin once-daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility Study Into the Contraceptive Effect of Estetrol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: estetrol|DRUG: estetrol|DRUG: estetrol and desogestrel|DRUG: estetrol and progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Expected Benefit of Extra-corporeal-shockwave Therapy (ESWT) Treatment to Standard Care in Treating Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot
Interventions: DEVICE: shock wave therapy|DEVICE: dermagold shockwave|PROCEDURE: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of AZD9898
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: AZD9898|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DRUG: SAS0421a|DRUG: SAS0421b|DRUG: SAS0421c|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Bitopertin to Evaluate the Safety, Tolerability, Efficacy, and PPIX Concentrations in Participants With EPP
Status: ACTIVE_NOT_RECRUITING
Conditions: Erythropoietic Protoporphyria
Interventions: DRUG: DISC-1459|DRUG: DISC-1459|DRUG: Placebo|DRUG: DISC-1459
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemonitoring of Patients With COPD in Carinthia
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive (COPD)
Interventions: OTHER: self-monitoring for patients with severe COPD|OTHER: nurse-monitoring for patients with severe COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Intervention on Psychosocial Health in Women With Unsuccessful IVF Experience
Status: NOT_YET_RECRUITING
Conditions: Infertility|Failed in Vitro Fertilisation
Interventions: OTHER: Web-based support program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: UMCCOP 02-01 Ginger in Treating Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Nausea and Vomiting|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ginger extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Probiotics and the Development of Clostridium Difficile Associated Diarrhea in Patients Receiving Antibiotics
Status: UNKNOWN
Conditions: Development of Clostridium Difficile Associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Theralac probiotic|DIETARY_SUPPLEMENT: Culturelle probiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of an Integrated Programme in Promoting the Regular Physical Activity Among Childhood Cancer Survivors
Status: COMPLETED
Conditions: Malignant Childhood Neoplasm
Interventions: BEHAVIORAL: health talk and adventure-based training|BEHAVIORAL: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Efficacy of Plan Blocks in Laparoscopic Hysterectomies
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetic Profile, Pharmacodynamic Effects, Acceptability and Tolerability of an Oral Amiodarone Solution of 15 mg / mL in Children With Supra Ventricular Tachycardia
Status: WITHDRAWN
Conditions: Supraventricular Tachycardia
Interventions: BIOLOGICAL: Assess the absorption of oral amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006)
Status: ACTIVE_NOT_RECRUITING
Conditions: PIK3CA-Related Overgrowth Spectrum (PROS)/Proteus Syndrome (PS)
Interventions: DRUG: Miransertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BMS-754807 Combined With Letrozole or BMS-754807 Alone in Patients With Hormone Receptor-Positive Breast Cancer and Resistance to Non-Steroidal Aromatase Inhibitors
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: BMS-754807|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Omalizumab Treatment on ICS Reduction for Severe IgE-mediated Asthma
Status: TERMINATED
Conditions: Severe IgE-mediated Asthma
Interventions: DRUG: Omalizumab|DRUG: Budesonide|DRUG: Formoterol|DRUG: Budesonide|DRUG: Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN)
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Pregabalin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How Different Doses of a New Medicine NNC0148-0287 C (Insulin 287) Work on the Blood Sugar in People With Type 1 Diabetes When it is Taken Once a Week
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin icodec|DRUG: IGlar U100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Therapeutics for Behavior Problems
Status: RECRUITING
Conditions: Problem Behavior|Child Behavior
Interventions: BEHAVIORAL: UseIt! App|BEHAVIORAL: Coach|BEHAVIORAL: SmilingMind App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Anti-CCR4 Monoclonal Antibody (Mogamulizumab) and Total Skin Electron Beam Therapy (TSEB) in Patients With Stage IB-IIB Cutaneous T-Cell Lymphoma
Status: RECRUITING
Conditions: Stage IB-IIB Cutaneous T-Cell Lymphoma
Interventions: DRUG: Mogamulizumab|RADIATION: Total Skin Electron Beam Therapy (TSEB)|DRUG: Mogamulizumab (subsequent cycles post TSEB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients
Status: COMPLETED
Conditions: Cystoid Macular Edema, Postoperative|Diabetes Mellitus
Interventions: DRUG: Ketorolac tromethamine ophthalmic solution 0.45%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of FB2001 for Inhalation in Patients With Mild to Moderate COVID-19
Status: RECRUITING
Conditions: Mild to Moderate COVID-19
Interventions: DRUG: FB2001|DRUG: FB2001 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Follow-up Versus Fluid Bolus in RESPONSE to Oliguria in the Critically Ill
Status: COMPLETED
Conditions: Critically Ill|Acute Kidney Injury|Sepsis|Oliguria
Interventions: OTHER: follow-up without intervention|OTHER: fluid bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IPV Clinical Trial - The Gambia
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: DRUG: IPV IM Needle|DRUG: IPV ID Needle|DRUG: IPV IM Device|DRUG: IPV ID Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Status: NOT_YET_RECRUITING
Conditions: Endometritis; Chronic|Subfertility
Interventions: DIAGNOSTIC_TEST: Microbiome study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of Factors Involved in the Regulation of Immune Responses After Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: BIOLOGICAL: Blood Sample|BIOLOGICAL: Bone marrow aspiration|BIOLOGICAL: Blood sample|BIOLOGICAL: Allogeneic hematopoietic stem cell sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy Study of Apremilast (CC-10004) in Subjects With Erosive Hand Osteoarthritis
Status: COMPLETED
Conditions: Erosive Osteoarthritis of the Hand
Interventions: DRUG: Apremilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dolutegravir and Darunavir Evaluation in Adults Failing Therapy
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: NRTIs|DRUG: Dolutegravir|DRUG: Darunavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Center of Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease
Status: COMPLETED
Conditions: Heart Disease|Brain Vascular Accident|Carotid Artery Disease|Carotid Stenosis
Interventions: DEVICE: Angioguard XP distal protection device|PROCEDURE: Heart Catheterization -Angioplasty|DEVICE: stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypofractionated Vs Conventional Fractionated Postmastectomy Radiotherapy for High Risk Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Hypofractionated|RADIATION: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: NLY01|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AXIOS CHINA (E7148)
Status: COMPLETED
Conditions: Pancreatic Pseudocyst and Walled-off Necrosis
Interventions: DEVICE: HOT AXIOS Stent and Electrocautery- Enhanced Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Clinical Trial of Neoadjuvant Relatlimab and Nivolumab in High Risk, Clinical Stage II Cutaneous Melanoma
Status: RECRUITING
Conditions: Stage II Melanoma
Interventions: DRUG: Relatlimab and nivolumab fixed dose combination (FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution
Status: ACTIVE_NOT_RECRUITING
Conditions: Keratoconus|Pellucid Marginal Corneal Degeneration|Corneal Degeneration|Corneal Ectasia
Interventions: COMBINATION_PRODUCT: PXL-330 Platinum device for crosslinking with Peschke riboflavin solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Program for Climacteric Women
Status: NOT_YET_RECRUITING
Conditions: Climacteric Syndrome|Postmenopausal Symptoms|Menopause|Perimenopausal Disorder
Interventions: OTHER: multimodal physiotherapy programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose Response of Calcium Co-ingested With Protein on GLP-1 Concentrations
Status: COMPLETED
Conditions: GLP-1 Concentration
Interventions: DIETARY_SUPPLEMENT: Dose response of Capolac®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial of the Ostial Versus the Extra-Ostial Ablation Strategy for Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrhythmia
Interventions: PROCEDURE: Catheter ablation (pulmonary vein isolation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced Cervical Cancer
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: RADIATION: Radiation therapy|DRUG: Carboplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head
Status: COMPLETED
Conditions: Brain Injuries, Traumatic|Concussion, Brain|Headaches Chronic|Headache|Post-Traumatic Headache|Mild Traumatic Brain Injury|Transcranial Magnetic Stimulation
Interventions: DEVICE: rTMS - Real Air Film Coil|DEVICE: rTMS - Sham Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of Soluble Dietary Fiber Supplementation
Status: COMPLETED
Conditions: Hypomotility|Constipation
Interventions: DRUG: Pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Bioequivalence of Pfizer Korea Inc. "XELJANZ 5Mg Tablet" in Healthy Volunteers
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: XELJANZ 5Mg Tablet|DRUG: Chong Kun Dang Tofacitinib Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shockwave Lithotripsy, Electroconductive and Electrohydraulic Types
Status: COMPLETED
Conditions: Urolithiasis
Interventions: DEVICE: Electroconductive and Electrohydraulic types
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT