pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of a Diagnostic Medical Device for the INR (International Normalized Ratio) Measurement
Status: COMPLETED
Conditions: Healthy|Heart Valves|Arrhythmias, Cardiac|Thromboembolism
Interventions: DEVICE: Self testing INR device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Economic Compensation to Increase Demand for Voluntary Medical Male Circumcision
Status: COMPLETED
Conditions: Voluntary Medical Male Circumcision|Circumcision Adult
Interventions: OTHER: Compensation for transport cost|OTHER: Compensation for lost wages|OTHER: Compensation for transport cost and lost wages|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Breast Cancer|Recurrent Breast Cancer
Interventions: DRUG: Experimental Arm A: Pemetrexed|DRUG: Experimental Arm A: Sorafenib|DRUG: Experimental Arm B: Pemetrexed|DRUG: Experimental Arm B: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Two Formulations of LX1033 in Healthy Human Subjects
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: 250 mg capsule|DRUG: 250 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scleroderma Treatment With Autologous Transplant (STAT) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Scleroderma
Interventions: BIOLOGICAL: Anti-Thymocyte Globulin|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Plerixafor|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.
Status: ENROLLING_BY_INVITATION
Conditions: Lymphoma, B-Cell|Lymphoma, Non-Hodgkin|Leukemia, B-cell|Graft Vs Host Disease|Solid Tumor
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy Associated With Exercise in Pain Control and Physical Function in Individuals With Knee Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis,Knee
Interventions: OTHER: EXERCISE PROTOCOL + CRYOTHERAPY|OTHER: EXERCISE PROTOCOL|OTHER: EXERCISE PROTOCOL + PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Pembrolizumab Following Weekly Paclitaxel for Platinum-resistant Ovarian, Fallopian Tube or Peritoneal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instructor-led Simulation Training Versus Self-directed Simulator Training During Simulated Neonatal Resuscitation
Status: COMPLETED
Conditions: Resuscitation|Neonatology
Interventions: OTHER: Video-assisted learning and self-directed training|OTHER: Simulation-based neonatal resuscitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: "Effects of Piezocision vs Micro-osteoperforations on the Rate of Maxillary Canine Retraction
Status: UNKNOWN
Conditions: Angle Class II, Division 1 Malocclusion
Interventions: PROCEDURE: Piezocision|PROCEDURE: Micro-osteoperforations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lyophilized Dried Cornus Mas L. on Anthropometric and Biochemical Parameters in Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance|Obesity|PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Cornelian Cherry (Cornus mas L.)|BEHAVIORAL: Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Chemoradiation With Immunotherapy in Inoperable œsophageal Cancer
Status: TERMINATED
Conditions: Inoperable œsophageal Cancer
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|OTHER: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Everolimus|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INSIGHTFUL-FFR Clinical Trial
Status: RECRUITING
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: PROCEDURE: Pressure Microcatheter guided strategy - PIOS MC|PROCEDURE: Pressure Wire guided strategy - PIOS - PW|PROCEDURE: Pressure Microcatheter guided strategy - Standard of care|PROCEDURE: Pressure Wire guided strategy - Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Oxaliplatin (GEMOX) in First Line Metastatic or Recurrent Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bladder Shaper Test
Status: COMPLETED
Conditions: Diagnosis of Urinary Tract Symptons
Interventions: DIAGNOSTIC_TEST: Bladder Shape Test|OTHER: Calibration images
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Shear Wave Elastography Technology to Evaluate the Efficacy of ESW in the Treatment of Patients With Chronic Plantar Fasciitis
Status: UNKNOWN
Conditions: Chronic Plantar Fasciitis
Interventions: DEVICE: Focused shockwave|OTHER: Home therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Validity, Reliability, and Feasibility of Two Smartphone Applications for Testing the Visual Acuity
Status: COMPLETED
Conditions: Vision Impairment|Blindness
Interventions: DEVICE: Assessment of distance and near visual acuity using "Vision Screening module" of "Easy Vision" application|DEVICE: Assessment of distance and near visual acuity using "Test Yourself module" of "Easy Vision" application|DEVICE: Assessment of distance and near visual acuity using "Peek Acuity" application|OTHER: Assessment of distance and near visual acuity using the conventional methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antithrombotic Triple Therapy in Humans
Status: COMPLETED
Conditions: Atrial Fibrillation|Acute Coronary Syndrome
Interventions: DRUG: Dabigatran, Ticagrelor, ASA|DRUG: Rivaroxaban, Ticagrelor, ASA|DRUG: Phenprocoumon, Ticagrelor, ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Flexible Mini Percutaneous Nephrolithotomy vs Retrograde Intra-renal Surgery
Status: RECRUITING
Conditions: Renal Stone
Interventions: PROCEDURE: flexible mini percutaneous nephrolithotomy|PROCEDURE: Retrograde intrarenal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WALANT in Distal Radius Fracture Osteosynthesis
Status: COMPLETED
Conditions: Radius Fracture Distal
Interventions: PROCEDURE: WALANT|PROCEDURE: Locoregional anesthesia and tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SURGICEL® Powder in Controlling Mild or Moderate Parenchymal or Soft Tissue Intraoperative Bleeding in Adult Subjects
Status: COMPLETED
Conditions: Hemorrhage
Interventions: DEVICE: SURGICEL Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Mobile System for Self-management of Schizophrenia (SOS)
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Mobile Application|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training Effectiveness in Sympathetic Activity and Functional Capacity in Patients With Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: RADIATION: Myocardial scintigraphy|DEVICE: Cardiopulmonary test|DEVICE: AVD-Glittre Test|DEVICE: Diaphragm ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Peanuts and Peanut Products on Glucose Control and Vascular Function
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Peanut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: Adebrelimab|DRUG: Lenvatinib|PROCEDURE: Hepatic Arterial Infusion Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Ivermectin and Doxycyline|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicomponent Intervention in Women at Risk of Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia|Grip Strength|Gait Speed|Body Composition
Interventions: OTHER: Multicomponent intervention of resistance exercises, dancing sessions and nutritional education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oral Adherence in Hematological Oncology Agents and Impact on Comorbid Therapy Adherence
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Multiple Myeloma|Multiple Chronic Conditions
Interventions: OTHER: Patient-reported outcome measure|OTHER: Comprehensive Medication Review|OTHER: Pharmacist communication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: nicotine|DRUG: menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Feasibility Study of Retinal Screening Using the RetinaVue 100 Camera in Outpatient Dialysis Centers
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Eye Diseases|Diabetic Retinopathy
Interventions: DEVICE: RetinaVue 100 camera
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics of Ruzasvir (MK-8408) in Participants With Hepatitis C Infection (MK-8408-003)
Status: COMPLETED
Conditions: Hepatitis C Infection
Interventions: DRUG: Ruzasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Forced Diuresis With Matched Hydration in Reducing Acute Kidney Injury During TAVI
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy|Aortic Valve Stenosis With Insufficiency
Interventions: DEVICE: Renal Guard|DRUG: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTSD and Self-regulation: Coping, Emotional Regulation and Cognitive Control and Their Relationships to Symptom Management
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: DIAGNOSTIC_TEST: questionnary administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy of Topialyse Baume barrière on Atopic Dermatis
Status: WITHDRAWN
Conditions: Atopic Dermatitis
Interventions: OTHER: Topialyse Baume Barrière
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 'Non-Invasive' Breath Test to Determine Anabolic Sensitivity in Females
Status: RECRUITING
Conditions: Dietary Protein|Female Protein Metabolism|Anabolic Sensitivity|Resistance Exercise|Young Adult Females
Interventions: BEHAVIORAL: Fed|BEHAVIORAL: Ex-Fed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer|Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Recurrent
Interventions: DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)
Status: COMPLETED
Conditions: Heterozygous Familial Hypercholesterolemia
Interventions: DRUG: LMT (atorvastatin, simvastatin, or rosuvastatin)|DRUG: alirocumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epigenetic Effects in Children With Cow's Milk Allergy Treated With Different Formulas
Status: RECRUITING
Conditions: Cow Milk Allergy
Interventions: DIETARY_SUPPLEMENT: EHCF+LGG|DIETARY_SUPPLEMENT: RHF|DIETARY_SUPPLEMENT: SF|DIETARY_SUPPLEMENT: EHWF|DIETARY_SUPPLEMENT: AAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dantrolene for Treatment of Hyperthermia in Subarachnoidal Hemorrhage (SAH)
Status: TERMINATED
Conditions: Hyperthermia
Interventions: DRUG: Dantrolene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Patient and Investigator Expectation on the Efficacy of Escitalopram in the Treatment Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Examining the Effects of a Remote Pulmonary Rehabilitation Program in the Severe Asthma Population.
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: BEHAVIORAL: Pulmonary rehab program|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: VEGF inhibitor PTC299
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: emixustat hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Leukemic Dendritic Cell Activated Donor Lymphocytes
Status: TERMINATED
Conditions: Leukemia, Myelocytic, Acute
Interventions: PROCEDURE: Apheresis|BIOLOGICAL: Stem Cell Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Tegafur/Uracil (UFUR®)Plus Thalidomide for the Treatment of Advanced or Metastatic Hepatocellular Carcinoma (HCC)
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Thalidomide(THADO), Tegafur/Uracil(UFUR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ramelteon Sublingual in Adult Patients With Acute Depressive Episodes Associated With Bipolar I Disorder
Status: TERMINATED
Conditions: Acute Depressive Episode
Interventions: DRUG: Ramelteon SL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Boiled Pasta|OTHER: Boiled Chickpeas with Oil|OTHER: Instant Mashed Potatoes|OTHER: Instant Mashed Potatoes with Egg Whites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of a Fifteen-minute Functional Exercise Intervention on Levels of Physical Fitness of Schoolchildren
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Fitness
Interventions: OTHER: Functional physical exercises|OTHER: Physical Education classes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of ISIS 113715 on Insulin Sensitivity, Glucose, and Lipid Metabolism and Energy Expenditure in Type 2 Diabetics
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ISIS 113715
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Bilevel positive airway pressure (BiPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With Nocturia
Status: COMPLETED
Conditions: Nocturia
Interventions: BEHAVIORAL: SyBeMeP (Systemized Behavioural Modification education Program)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Side Effects to FOLFOXIRI + Tocotrienol/Placebo as First Line Treatment of Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan 165 mg/m2 iv|DRUG: Oxaliplatin 85 mg/m2 iv|DRUG: Calcium folinate 200 mg/m2 iv|DRUG: 5-fluorouracil 3200 mg/m2|DIETARY_SUPPLEMENT: Tocotrienol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of ON 01910.Na in Refractory Myelodysplastic Syndrome Patients With Excess Blasts
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|MDS|RAEB|Chronic Myelomonocytic Leukemia
Interventions: DRUG: ON 01910.Na
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EGb 761® on Patients With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: EGb 761® (Tanakan®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Discriminating Power of a Blood Biomarker for Omega-3 Polyunsaturated Fatty Acid Content of the Retina for Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: BIOLOGICAL: blood sampling|BIOLOGICAL: faecal sampling (optional)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease
Status: RECRUITING
Conditions: Chronic Venous Insufficiency|Chronic Venous Thrombosis|Iliac Vein Stenosis|Iliac Vein Obstruction|Post Thrombotic Syndrome
Interventions: PROCEDURE: Deep venous stenting|COMBINATION_PRODUCT: Best medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Monotherapy Following Tri-modality Treatment for Selected Patients With Muscle-invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer|Bladder Neoplasms|Bladder Tumors|Urinary Bladder Cancer|Neoplasms, Bladder
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of DS-1093 in Healthy Subjects
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: DS-1093|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-, Peri- and Postnatal Programming and Origins of Disease: Early Targeting the Epidemics of Allergy and Overweight
Status: UNKNOWN
Conditions: Allergic Disease|Obesity|Immunology
Interventions: BEHAVIORAL: Dietary counselling and placebo|BEHAVIORAL: Dietary counselling and probiotics|DIETARY_SUPPLEMENT: Placebo capsules|DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Prebiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid-based Versus Opioid-free Anaesthesia for Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Surgical Procedure, Unspecified|Laparoscopic Cholecystectomy
Interventions: DRUG: Dexmedetomidine injection|DRUG: Nalbuphine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Retreated Clevudine in Chronic HBV Patients Who Received Clevudine in L-FMAU-201
Status: TERMINATED
Conditions: Hepatitis B
Interventions: DRUG: Clevudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Tuberculosis and Vitamin D
Status: UNKNOWN
Conditions: Tuberculosis
Interventions: DRUG: Cholecalciferol|DRUG: Lactose granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Cardiac Biomarker Assay
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Acute Myocardial Infarction
Interventions: DEVICE: ARCHITECT STAT High Sensitive Troponin I Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Health Effects of Short-term Use of E-cigarettes on Pulmonary and Cardiovascular System
Status: COMPLETED
Conditions: E-cigarette
Interventions: BEHAVIORAL: Cigarette smoking|BEHAVIORAL: E-cigarette use|BEHAVIORAL: Simulation of the use of e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan With Docetaxel in Treating Patients With Recurrent or Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: docetaxel|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Drug Delivery System - Silk Fibroin Film Loaded or Not With Insulin on Palatal Mucosa Wound Healing
Status: UNKNOWN
Conditions: Wound Healing|Insulin|Palate; Wound
Interventions: PROCEDURE: Palatal Wound|DEVICE: Palatal Wound treated with Silk Fibroin Film|DEVICE: Palatal Wound treated with Insulin-loaded Silk Fibroin Film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Geographic Atrophy|Age-related Macular Degeneration
Interventions: DRUG: LFG316|DRUG: Sham|DRUG: LFG316 Lower dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Quality of Ocular Akinesia (Onset and Duration)
Interventions: DRUG: Atracurium|DRUG: Lidocaine 2%|DRUG: Bupivacaine 0.5%|DRUG: hyaluronidase powder|PROCEDURE: per-caruncular peribulbar injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doravirine (DOR) in Human Immunodeficiency Virus (HIV)-Infected Children Ages 4 Weeks to <12 Years and <45 kg (MK-1439-066)
Status: RECRUITING
Conditions: Human Immunodeficiency Virus (HIV) Infection
Interventions: DRUG: Doravirine|DRUG: 2 NRTIs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder
Status: COMPLETED
Conditions: Binge-Eating Disorder
Interventions: DRUG: Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rocuronium and Org 25969 With Cisatracurium and Neostigmine (19.4.310)(P05931)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex|DRUG: neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Banana Leaf Dressing on Donor Site Wounds
Status: UNKNOWN
Conditions: Burn
Interventions: DEVICE: Banana Leaf Dressing|DRUG: Hydrocolloid Dressing (DuoDERM CGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: enHEART - Exploring Full Content of Optical Signals to Enhance Cardiac Arrhythmia Screening
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation|Atrial Flutter|Atrioventricular Block|Nodal Tachycardia|Atrioventricular Tachycardia|Ventricular Tachycardia|Premature Ventricular Contraction|Premature Atrial Complex
Interventions: OTHER: Validating and improving PPG-based algorithms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Relationship Between Serum Gasdermin-D Levels and Pyroptosis and Preterm Labor
Status: COMPLETED
Conditions: Gasdermin D Levels in Preterm Labor
Interventions: OTHER: Gasdermin-d
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of ZGGS18 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: ZGGS18 for Injection|BIOLOGICAL: ZGGS18 for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Placebo Controlled Study of OXN PR for Severe Parkinson's Disease Associated Pain
Status: COMPLETED
Conditions: Parkinson's Disease With Severe Pain
Interventions: DRUG: Oxycodone/Naloxone Prolonged Release tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of VS-505(AP301) to Treat Hyperphosphatemia in Hemodialysis Patients
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: VS-505|DRUG: Sevelamer Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anxiety Self-Management for ICU Patients Receiving Mechanical Ventilation
Status: COMPLETED
Conditions: Anxiety
Interventions: BEHAVIORAL: Anxiety Self-Management, Patient preferred relaxing music|BEHAVIORAL: Control 1: Noise-cancelling headphones|BEHAVIORAL: Control 2: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia A
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: turoctocog alfa pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Targeting Motivational Negative Symptoms
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Bipolar Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Switch - Individual sessions|BEHAVIORAL: Switch - Group programme
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Invasive Cervical Cancer: The Importance of Expectant Management in Young Women With High-grade Pre-cancerous Lesions
Status: COMPLETED
Conditions: High-Grade Squamous Intraepithelial Lesions
Interventions: OTHER: Data extraction from medical files|BIOLOGICAL: Immunohistochemistry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Peers and Technology for Adherence, Access, Accountability, and Analytics (PT4A)
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Disease|Hypertension
Interventions: OTHER: Peer Delivery of Medications|OTHER: Health Information Technology (HIT) Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Safety, Tolerability, and Changes in Biomarker and Clinical Outcome Assessments of Losmapimod for FSHD1 With Extension
Status: ACTIVE_NOT_RECRUITING
Conditions: Facioscapulohumeral Muscular Dystrophy 1
Interventions: DRUG: Losmapimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen as a Possible Preventer of Post Bronchoscopy Fever
Status: COMPLETED
Conditions: Post Bronchoscopy Fever
Interventions: DRUG: ibuprofen|DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exenatide for Smoking Cessation and Prevention of Weight Gain
Status: RECRUITING
Conditions: Smoking Cessation|Weight Gain
Interventions: DRUG: Exenatide 2 milligram (mg) Injection|DRUG: Placebo|DRUG: Nicotine patch|BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: everolimus|DRUG: temozolomide|GENETIC: microarray analysis|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Daunorubicin Cytarabine Liposomes in Naive AML Patients
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Daunorubicin Cytarabine liposome for injection|DRUG: Vyxeos、Daunorubicin Cytarabine liposome for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eyelid Androgen Treatment in Dry Eye
Status: RECRUITING
Conditions: Aqueous Tear Deficiency|Meibomian Gland Dysfunction of Bilateral Eyes (Disorder)
Interventions: DRUG: Testosterone gel 4.5%|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Boostrix Polio Vaccine as a Booster Dose in 5 to 6-year-old Children.
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Diphtheria|Poliomyelitis
Interventions: BIOLOGICAL: Boostrix Polio™ 711866|BIOLOGICAL: Priorix Tetra TM 208136|BIOLOGICAL: Tetravac TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Different DAV132 Dose Regimens in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Moxifloxacin|DEVICE: DAV132|OTHER: Negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Cediranib in Combination With Olaparib in Patients With Recurrent Platinum-Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Platinum Resistant Ovarian Cancer
Interventions: DRUG: cediranib and olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Phase 2 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children
Status: COMPLETED
Conditions: Pediatric Growth Hormone Deficiency
Interventions: DRUG: MOD-4023|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia
Status: RECRUITING
Conditions: Tetraplegia/Tetraparesis
Interventions: PROCEDURE: BES + TS|PROCEDURE: Experimental: BES+sham TS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Decision Support for Adults Facing Implantable Cardioverter-Defibrillator Pulse Generator Replacement
Status: COMPLETED
Conditions: Death, Sudden, Cardiac|Death, Sudden|Cardiovascular Diseases
Interventions: BEHAVIORAL: Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of AK0529 to Evaluate Pharmacokinetics and Safety in Chinese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AK0529|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effect of Triheptanoin Compared With Even-chain, MCT on MCEs in Pediatric Patients With LC-FAOD
Status: RECRUITING
Conditions: Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)
Interventions: DRUG: Triheptanoin|DIETARY_SUPPLEMENT: MCT Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Central Line Hub Contamination Using a Novel Capping Device
Status: UNKNOWN
Conditions: Catheter-related Bloodstream Infection Due to Central Venous Catheter
Interventions: DEVICE: Disinfecting Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose-Escalation Study Evaluating the Combination of Trastuzumab Emtansine (T-DM1) With Neratinib in Women With Metastatic HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Neratinib|DRUG: T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Monocentric Study Assessing the Efficacy of the Nitrosylated Hemoglobin as Biomarker for Detecting the Development of a Cardiovascular Complication During or After Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Complications
Interventions: DIAGNOSTIC_TEST: Blood sampling for HbNO assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Screening For BCRL In Targeted Therapy For Breast Cancer
Status: RECRUITING
Conditions: Lymphedema|Lymphedema Arm|Lymphedema of Upper Arm|Lymphedema of Upper Limb|Lymphedema of the Hands|Edema|Edema Arm|Breast Cancer Lymphedema|Breast Cancer Metastatic|Breast Cancer Stage|Breast Cancer
Interventions: DEVICE: Perometer|DEVICE: SOZO device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Clinical Efficacy and Safety of Nuvastatic™ - C5OSEW5050ESA in Diabetic Retinopathy.
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Nuvastatic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sensory Attention Focused Exercise in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: OTHER: Sensory Attention Focused Exercise (SAFEx)|OTHER: Sensory Attention Focused Exercise (SAFEx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Azithromycin and Artesunate in Pregnant Women
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Sulfadoxine-Pyrimethamine|DRUG: Azithromycin|DRUG: Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Guanfacine in Children With Tic Disorders
Status: COMPLETED
Conditions: Tourette Disorder|Tourette Syndrome
Interventions: DRUG: placebo|DRUG: extended-release guanfacine (Intuniv)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soy Isoflavones in Preventing Head and Neck Cancer Recurrence in Patients With Stage I-IV Head and Neck Cancer Undergoing Surgery
Status: COMPLETED
Conditions: Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Laryngeal Verrucous Carcinoma|Recurrent Lip and Oral Cavity Squamous Cell Carcinoma|Recurrent Oral Cavity Verrucous Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Stage I Hypopharyngeal Squamous Cell Carcinoma|Stage I Laryngeal Squamous Cell Carcinoma|Stage I Laryngeal Verrucous Carcinoma|Stage I Lip and Oral Cavity Squamous Cell Carcinoma|Stage I Oral Cavity Verrucous Carcinoma|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Hypopharyngeal Squamous Cell Carcinoma|Stage II Laryngeal Squamous Cell Carcinoma|Stage II Laryngeal Verrucous Carcinoma|Stage II Lip and Oral Cavity Squamous Cell Carcinoma|Stage II Oral Cavity Verrucous Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma|Stage III Laryngeal Squamous Cell Carcinoma|Stage III Laryngeal Verrucous Carcinoma|Stage III Lip and Oral Cavity Squamous Cell Carcinoma|Stage III Oral Cavity Verrucous Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IV Hypopharyngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Verrucous Carcinoma|Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma|Stage IVA Oral Cavity Verrucous Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Tongue Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Soy Isoflavones|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study
Status: COMPLETED
Conditions: Poorly Differentiated Malignant Neuroendocrine Carcinoma|Neuroendocrine Carcinoma, Grade 3|Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3|Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma] That Switched to G3|Neuroendocrine Tumor, Grade 3 and Disease Progression as Measured by Response Evaluation Criteria in Solid Tumors (RECIST 1.1.)
Interventions: DRUG: Everolimus (Afinitor®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcinosis Cutis: Therapeutic Effects of Extracorporeal Shock Wave Therapy (ESWT)
Status: COMPLETED
Conditions: Calcinosis Cutis in Connective Tissue Disease
Interventions: DEVICE: shock wave therapy with Modulith SLK (Storz)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topically Applied AMTX-100 CF for Adult Patients With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: 1.1% w/w AMTX-100 CF-part1|DRUG: Placebo|DRUG: 1.1% w/w AMTX-100 CF3-part2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Effectiveness of Continuous Non-invasive Haemodynamic Monitor by Compared to Invasive Blood Pressure and Pulse Oximeter Monitoring on Patients Undergoing General Anesthesia Surgeries for More Than 60 Minutes
Status: NOT_YET_RECRUITING
Conditions: General Anesthesia|Blood Pressure|Pulse Rate|Arterial Line
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Solifenacin Succinate Compared to Tolterodine in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Solifenacin succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT