pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Efficacy of Nebulizing Budesonide and Intravenous Dexamethasone Before Extubation on Prevention of Post-extubation Complications in Intensive Care Unit Patients
Status: UNKNOWN
Conditions: Respiratory Sounds
Interventions: DRUG: Budesonide|DRUG: Dexamethasone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Long-term Study to Evaluate the Safety of Eplerenone in the Treatment of Hypertension in Children Aged 6 to 16 Years
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevelamer, FGF-23 and Endothelial Dysfunction in Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: We Investigated the Relationship Between Plasma FGF23 Levels and Endothelial Dysfunction in a Sizable Series of Incident Stage 3-4 CKD Patients.
Interventions: DRUG: Sevelamer|DRUG: calcium acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Nano-Pulse Stimulation (NPS) in Seborrheic Keratosis Optimization Study
Status: TERMINATED
Conditions: Lesion Skin|Seborrheic Keratosis|Skin Lesion|Benign Skin Tumor
Interventions: DEVICE: Nano-Pulse Stimulation (NPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beneficial Effects of Grape Seed Proanthocyanidin Extrat on Progression of Atherosclerotic Plaques in Clinical Use
Status: COMPLETED
Conditions: Atherosclerosis of Arteries of the Extremities, Unspecified
Interventions: DRUG: GSPE|OTHER: lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Regular Use Tiotropium and Tolerance to Bronchoprotection in Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Tiotropium Bromide|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Randomized Double-blind Placebo-controlled Trial of Intralesional Botulinum Toxin A Injection for Recalcitrant Alopecia Totalis and Alopecia Universalis
Status: COMPLETED
Conditions: Recalcitrant Alopecia Totalis|Recalcitrant Alopecia Universalis
Interventions: DRUG: Botulinum toxin A|DRUG: Normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Myelomonocytic Leukemia|Neurofibromatosis Type 1
Interventions: PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Cigarette Smoking
Interventions: DRUG: Nicotine replacement therapy|DRUG: Bupropion|BEHAVIORAL: cognitive-behavioral smoking cessation counseling|BEHAVIORAL: Mobile Contingency Management|BEHAVIORAL: Stay Quit Coach|BEHAVIORAL: SMS text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NICU Asthma Education and Secondhand Smoke Reduction Study
Status: COMPLETED
Conditions: Respiratory Illness
Interventions: BEHAVIORAL: Secondhand Smoke Reduction and Smoking Cessation Counseling|BEHAVIORAL: Asthma Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Sand on Knee Load and Muscle Activity During a Single Leg Landing Task
Status: COMPLETED
Conditions: Single Leg Hop Sand Surface|Single Leg Hop Grass Surface|Single Leg Hop Firm Surface
Interventions: OTHER: Sand|OTHER: artificial grass|OTHER: firm ground
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorpromazine and Standard of Care in Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Chlorpromazine|DRUG: Temozolomide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Comprehensive Diagnosis and Treatment for Children Precocious Puberty
Status: COMPLETED
Conditions: Central Precocious Puberty
Interventions: DRUG: Triptorlin or Leuprorelin|DRUG: Zhibo dihuang pills|DRUG: Dabu ying pills
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Intervention of Idecalcitol Combined With Whey Protein Powder and Exercise for Sarcopenia
Status: RECRUITING
Conditions: Sarcopenia
Interventions: BEHAVIORAL: exercise|DIETARY_SUPPLEMENT: whey protein powder|DRUG: Eldecalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion (HAI) With Floxuridine (FUDR) and Dexamethasone (Dex) Combined With Systemic Gemcitabine and Oxaliplatin in Patients With Unresectable Intrahepatic Cholangiocarcinoma (ICC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma|Peripheral Cholangiocarcinoma|Cholangiolar Carcinoma|Cholangiocellular Carcinoma
Interventions: DRUG: Floxuridine (FUDR)|DRUG: dexamethasone|DRUG: Gemcitabine|DRUG: Oxaliplatin|OTHER: MRI|OTHER: Research blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on Symptoms of Female Pelvic Organ Prolapse(Level II - III)
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: electroacupuncture|OTHER: sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis
Status: RECRUITING
Conditions: Chronic Pancreatitis
Interventions: PROCEDURE: EUS-guided celiac plexus block|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
Status: COMPLETED
Conditions: Facial Rhytides|Crow's Feet Lines|Glabellar Lines
Interventions: DRUG: normal saline|BIOLOGICAL: onabotulinumtoxinA 44 U|BIOLOGICAL: onabotulinumtoxinA 24 U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of LCZ696 in Subjects With Mild and Moderate Renal Impairment Compared to Healthy Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Mild and Moderate Renal Impairment
Interventions: DRUG: LCZ696
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy of Sodium-glucose Co-transporter 2 Inhibitor or Dipeptidyl Peptidase-4 Inhibitor in Type 2 Diabetes Patients With Premix Insulin
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: DRUG: SGLT2 inhibitor (Empagliflozin 25 MG)|DRUG: DPP4 inhibitor (Linagliptin 5 MG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FDOPA PET in Neuroendocrine Tumours
Status: NO_LONGER_AVAILABLE
Conditions: Thyroid Cancer, Medullary|Carcinoid Tumor|Pheochromocytoma|Paraganglioma|Insulinoma|Neuroblastoma
Interventions: DRUG: [18 F]-6-L-fluorodihydroxyphenylalanine (18F-FDOPA)
Study Type: EXPANDED_ACCESS
Clinical trial: ElastoMeric Infusion Pumps for Hospital AntibioTICs
Status: ACTIVE_NOT_RECRUITING
Conditions: Infection, Bacterial
Interventions: DEVICE: To assess the feasibility of giving intravenous antibiotics to adult inpatients using elastomeric infusion pumps (EMPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Hypofractionated Radiotherapy Versus Stereotactic Irradiation With Hyaluronic Acid
Status: COMPLETED
Conditions: Prostatic Adenocarcinoma
Interventions: RADIATION: Moderate hypofractionated radiotherapy|RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab or Glofitamab in Combination With CC-220 and CC-99282 in Participants With B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: SC Mosunetuzumab|DRUG: IV Glofitamab|DRUG: CC-220|DRUG: CC-99282|DRUG: Obinutuzumab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Apixaban|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficiency of Gonadotropin-releasing Hormone (GnRH) Agonist in Preventing Chemotherapy Induced Ovarian Failure
Status: COMPLETED
Conditions: Fertility Preservation|Alkylating Agents|Lymphoma
Interventions: DRUG: Triptorelin|DRUG: Norethisterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalnce Study of Loratadine / Pseudoephedrine Sulfate 10/ 240 mg Extended-Release Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Loratadine 10mg /Pseudoephedrine Sulfate 240 mg Extended-Release Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study Comparing the Supraglottic Airway Devices and Endotracheal Tube During Controlled Ventilation for Laparoscopic Surgery
Status: UNKNOWN
Conditions: The Comparison of the I-gel and Endotracheal Tube About in Different Ventilation Settings During Laparoscopic Surgery
Interventions: DEVICE: i-gel|DEVICE: endotracheal tube|DRUG: lidocaine, propofol, fentanyl and cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tecemotide (L-BLP25) in Participants With Stage III Unresectable Non-small Cell Lung Cancer (NSCLC) Following Primary Chemoradiotherapy
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Tecemotide (L-BLP25)|DRUG: Single low dose cyclophosphamide|BIOLOGICAL: Placebo|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Warming Prevents Postoperative Hypothermia in Laparoscopic Gynecologic Surgery. A Randomized Control Trial
Status: COMPLETED
Conditions: Hypothermia Following Anesthesia|Hypothermia|Hypothermia, Accidental|Body Temperature Changes|Hypothermia Due to Anesthetic
Interventions: DEVICE: 3M Bair Paws Warming System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Arthritis
Interventions: DRUG: Adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS and Cognitive Training for Mild Cognitive Impairment and Alzheimer's Dementia
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DEVICE: Active Transcranial Direct Current Stimulation (tDCS)|DEVICE: Sham Transcranial Direct Current Stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Difluprednate vs. a Prednisolone Acetate - Phenylephrine on Post-operative Inflammation Following Cataract Surgery.
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Difluprednate Ophthalmic Emulsion 0.05%|DRUG: Prednisolone Acetate 1% Phenylephrine hydrochloride 0,12% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Efficacy and Safety of SM03 in Patients With Active Rheumatoid Arthritis Receiving MTX
Status: UNKNOWN
Conditions: Rheumatoid Arthritis(RA)
Interventions: DRUG: SM03|DRUG: Placebo|DRUG: MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety & Efficacy of Leukine® in the Treatment of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Sagramostim|DRUG: Saline -- placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing GSK1349572 50mg Plus Abacavir/Lamivudine Once Daily to Atripla (Also Called The SINGLE Trial)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I
Interventions: DRUG: Dolutegravir|DRUG: Atripla|DRUG: Abacavir/Lamivudine|DRUG: Abacavir/Lamivudine Placebo|DRUG: Dolutegravir placebo|DRUG: Atripla placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of RP101 in Post-menopausal Women With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: RP101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Insulin like growth factor, type 1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Oral Palbociclib (PD-0332991), A CDK4/6 Inhibitor, As Single Agent In Japanese Patients With Advanced Solid Tumors Or In Combination With Letrozole For The First-Line Treatment Of Postmenopausal Japanese Patients With ER (+) HER2 (-) Advanced Breast Cancer
Status: COMPLETED
Conditions: Neoplasms|Breast Neoplasms
Interventions: DRUG: PD-0332991|DRUG: PD-0332991|DRUG: letrozole|DRUG: PD-0332991|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients
Status: COMPLETED
Conditions: Cardiorenal Syndrome|Chronic Allograft Nephropathy
Interventions: DRUG: Paricalcitol|DRUG: Calcitriol|DRUG: Cholecalciferol|DIETARY_SUPPLEMENT: Supplemental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Of Lenalidomide As Maintenance Therapy In Patients With Newly Diagnosed Multiple Myeloma Following A Tandem Autologous-Allogeneic Transplant
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Clinical Activity and Safety of Oral NX-13 in Moderate to Severe Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: NX-13 250mg|DRUG: NX-13 750mg|DRUG: NX-13 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Harm Reduction Strategies for Gay, Bisexual and Other Men Who Have Sex With Men Engaging in Chemsex
Status: ENROLLING_BY_INVITATION
Conditions: Harm Reduction
Interventions: BEHAVIORAL: Mobile app to reduce harm of chemsex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin
Status: COMPLETED
Conditions: Familial Hypercholesterolemia
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics Supplementation and Intestinal Microbiome in Neonates With Gastrointestinal Surgery
Status: TERMINATED
Conditions: Probiotics|Infant, Newborn|Surgical Procedures, Operative|Gastro-Intestinal Disorder
Interventions: BIOLOGICAL: FloraBaby|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting in Patients With Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Atrial Fibrillation|Obstructive Sleep Apnea|Coronary Artery Bypass Grafting
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Compression Stockings on Obstructive Sleep Apnea in Patients Under Hemodialysis
Status: COMPLETED
Conditions: Renal Failure Chronic Requiring Dialysis|Obstructive Sleep Apnea
Interventions: DEVICE: Compression Stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitor Treatment Stop
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: esomeprazole|PROCEDURE: Helicobacter pylori c-13 breath test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monofocal IOL Visual Outcomes When Targeting Mini Monovision
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: Eyhance IOL|DEVICE: Eyhance IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Efficacy and Safety of DA-1241 in Subjects With Presumed NASH
Status: ACTIVE_NOT_RECRUITING
Conditions: NON-ALCOHOLIC STEATOHEPATITIS
Interventions: DRUG: DA-1241|DRUG: Sitagliptin|DRUG: DA-1241 Placebo|DRUG: Sitagliptin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngoscope-assisted Lightwand Intubation and Cervical Spine Motion
Status: UNKNOWN
Conditions: Intubation; Difficult
Interventions: DEVICE: laryngoscope-assisted lightwand intubation|DEVICE: traditional lightwand intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Bronchial Colonization With Fungi and Late Respiratory Acquired Pneumonia
Status: COMPLETED
Conditions: Ventilator Acquired Pneumonia
Interventions: PROCEDURE: biological sampling|PROCEDURE: sampling blood|PROCEDURE: endotracheal aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Moderately to Severely Active Rheumatoid Arthritis
Interventions: DRUG: HLX01|DRUG: Methotrexate（MTX）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imiquimod and Influenza Vaccine for Immunocompromised Patients
Status: COMPLETED
Conditions: Influenza Vaccine
Interventions: BIOLOGICAL: Intanza|BIOLOGICAL: Mutagrip|DRUG: Aldara
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Point-of-Care Adipose-derived Cells for Hair Growth
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: PROCEDURE: Stromal Vascular Fraction Cells (SVF Cells) Injection|PROCEDURE: Liposuction|OTHER: Hair Measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetirizine Hydrochloride Tablets, 10 mg Bioequivalence Study of Dr.Reddy's Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cetirizine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining Broad Based Light (BBL), Fractionated 1927 (MOXI) and Dual Wavelength 2940/1470 (HALO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pigment Skin
Interventions: DEVICE: Sciton Joule System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-dose, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DDO-3055 Tablets in Healthy Subjects.
Status: UNKNOWN
Conditions: Renal Anemia
Interventions: DRUG: DDO-3055 tablets；Placebo|DRUG: DDO-3055 tablets；Placebo|DRUG: DDO-3055 tablets；Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Use of Oxygen Reserve Index in Preventing Hyperoxia in the Intensive Care Unit.
Status: COMPLETED
Conditions: Hyperoxia|Complication|Mechanical Ventilation Complication
Interventions: PROCEDURE: Titration of fraction of inspired oxygen (FiO2) guided by ORI and oxygen saturation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Drug-Drug Interaction of TQ05105 Tablets
Status: NOT_YET_RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: TQ05105 tablets|DRUG: Itraconazole capsule|DRUG: Rifampicin Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Commonly Used Antibiotic, Doxycycline, in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome (PCOS)|Irregular Menstrual Cycles|Androgen Excess
Interventions: DRUG: doxycycline|OTHER: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Oral Steroid Alone Versus Oral Steroid Plus Intratympanic Steroid Injection in Bell's Palsy
Status: NOT_YET_RECRUITING
Conditions: Bell Palsy
Interventions: DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: Portico transcatheter aortic valve|DEVICE: Commercially available transcatheter aortic valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Clerio Vision LIRIC-modified Bifocal Contact Lens|DEVICE: Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens|DEVICE: Johnson & Johnson 1-Day Acuvue Moist Contact Lens|DEVICE: Clerio Vision Single Vision Contact Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BOTOX® Open-Label Treatment in Pediatric Upper Limb Spasticity
Status: COMPLETED
Conditions: Pediatrics|Muscle Spasticity|Cerebral Palsy|Stroke
Interventions: BIOLOGICAL: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Relatlimab in Combination With Nivolumab in Participants With Advanced Liver Cancer Who Have Never Been Treated With Immuno-oncology Therapy After Prior Treatment With Tyrosine Kinase Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Hepatoma|Liver Cancer, Adult|Liver Cell Carcinoma|Liver Cell Carcinoma, Adult
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surgery
Status: UNKNOWN
Conditions: Persistent Post-surgical Pain|Neuropathic Pain|Cancer Pain
Interventions: DRUG: Protective analgesia|OTHER: Pain education|BEHAVIORAL: Psychological support|PROCEDURE: Paravertebral block/local anaesthetic infiltration|OTHER: Daily visits from pain team whilst in hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: General Anesthesia, Versus Axillary Block for Ambulatory Hand Surgery: Randomized Prospective Study
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: fentanyl 2µg/kg intravenously and maintained with isoflurane|PROCEDURE: Axillary nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Farlong® NotoGinseng™ (Ginseng Plus®) on Cholesterol and Blood Pressure
Status: COMPLETED
Conditions: Hyperlipidemias|Hypertension
Interventions: DIETARY_SUPPLEMENT: Farlong NotoGinseng™ (Farlong Ginseng Plus® Panax Notoginseng extract)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Platelet Rich Plasma Following Hysteroscopic Adhesolysis
Status: COMPLETED
Conditions: Intra-uterine Adhesions
Interventions: PROCEDURE: Platelet Rich Plasma|PROCEDURE: intra-uterine balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perinatal Care and Medication Assisted Treatment: Carbon/Emery Counties
Status: COMPLETED
Conditions: Opioid-use Disorder|Pregnancy Related
Interventions: OTHER: Perinatal Opioid Use Disorder Education and Enhanced Perinatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Combined Robotic Hand Therapy and Conventional Therapy in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Robot Assisted Therapy|Robotic Rehabilitation
Interventions: PROCEDURE: Robot assisted therapy|PROCEDURE: Conventional Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Application of Image-Guided Liver Surgery
Status: TERMINATED
Conditions: Hepatocellular Cancer
Interventions: DEVICE: Explorer Liver Image Guided System|DEVICE: Explorer Liver Passive Tracking|PROCEDURE: Liver surgery|PROCEDURE: Liver abalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency
Status: RECRUITING
Conditions: Primary Immune Deficiency
Interventions: BIOLOGICAL: GC5107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iliohypogastric and Ilioinguinal Nerve Block for Acute and Chronic Pain Relief After Cesarean Section.
Status: COMPLETED
Conditions: Iliohypogastric and Ilioinguinal Nerve Block for Acute and Chronic Pain in Cesarean Section
Interventions: PROCEDURE: Iliohypogastric and ilioinguinal nerve block|PROCEDURE: Controlled Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Ad26.Mos4.HIV|BIOLOGICAL: Clade C and Mosaic gp140 HIV bivalent vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Short-term Prehabilitation Program : Interest of on Resumption of Function at 2 Months
Status: WITHDRAWN
Conditions: Thoracic Diseases|Urologic Diseases
Interventions: BEHAVIORAL: Short term prehabilitation (2 weeks)|OTHER: No specific intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: TRV130 1.5 mg|DRUG: TRV130 3 mg|DRUG: TRV130 4.5 mg|DRUG: Morphine 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anlotinib and Radiotherapy in Resectable Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma|High Risk of Recurrence|Anlotinib|Radiotherapy
Interventions: DRUG: Anlotinib|RADIATION: Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of TQB2618 Injection Combined With TQB2450 Injection in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: TQB2618 injection and TQB2450 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Calmoseptine Ointment and Desitin Diaper Rash Paste in Diaper Dermatitis in Neonates and Infants
Status: COMPLETED
Conditions: Diaper Dermatitis
Interventions: DRUG: Calmoseptine Ointment|DRUG: Destin Maximum Strength 40% Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Educating Brain Tumor Patients Using Patient-specific Actual-size Three-dimensional Printed Models
Status: UNKNOWN
Conditions: Brain Tumor|Glioma|Glioblastoma|Astrocytoma|Neoplasm, Brain|Oligodendroglioma|Patient Education as Topic|Decision Making, Shared
Interventions: DEVICE: Three-dimensional printed model
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Nucleos(t)ide (NUC)|DRUG: CpAM (RO7049389)|DRUG: TLR7 (RO7020531)|DRUG: siRNA (RO7445482)|DRUG: PEG-IFN|DRUG: PD-L1 LNA (RO7191863)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care
Status: NOT_YET_RECRUITING
Conditions: Asthma|Asthma in Children
Interventions: BEHAVIORAL: Hospital to Home Transition (H2H)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Study of Aerobic Exercise in Older Adults
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BEHAVIORAL: Nonexercise control group|BEHAVIORAL: Aerobic Exercise Group 1|BEHAVIORAL: Aerobic Exercise Group 2|BEHAVIORAL: Aerobic Exercise Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients
Status: COMPLETED
Conditions: Liver Transplantation|Kidney Transplantation
Interventions: DRUG: Tacrolimus granules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in HBV-related Liver Transplant Recipients
Status: COMPLETED
Conditions: Hepatitis B Infection
Interventions: BIOLOGICAL: GC1102 50,000 IU|BIOLOGICAL: GC1102 80,000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation With MRI-Guided SBRT Boost in Renal Cell Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Microwave Ablation (MWA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of Genome Editing by the Zinc Finger Nuclease (ZFN) Therapeutic SB-318 in Subjects With MPS I
Status: TERMINATED
Conditions: MPS I
Interventions: BIOLOGICAL: SB-318
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Idalopirdine in Healthy Subjects
Status: WITHDRAWN
Conditions: Bioequivalence
Interventions: DRUG: Idalopirdine commercial tablet (test)|DRUG: Idalopirdine clinical tablet (reference)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginally Assisted Laparoscopic Sacropolpopexy
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Vaginally assisted laparoscopic sacrocolpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economics for Activity Motivation in Adolescents (BEAM)
Status: RECRUITING
Conditions: Type 2 Diabetes|PreDiabetes|Insulin Resistance|Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: 1RLD|BEHAVIORAL: 1RLW|BEHAVIORAL: 1RGD|BEHAVIORAL: 1RGW|BEHAVIORAL: 2RLD|BEHAVIORAL: 2RLW|BEHAVIORAL: 2RGD|BEHAVIORAL: 2RGW|BEHAVIORAL: 1FLD|BEHAVIORAL: 1FLW|BEHAVIORAL: 1FGD|BEHAVIORAL: 1FGW|BEHAVIORAL: 2FLD|BEHAVIORAL: 2FLW|BEHAVIORAL: 2FGD|BEHAVIORAL: 2FGW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes.
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Vitamine C|DRUG: Liraglutide 6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation
Status: WITHDRAWN
Conditions: Hypoxia|Hypercapnia
Interventions: DRUG: L-NMMA|DRUG: Ketorolac|DRUG: Ascorbic Acid|PROCEDURE: Intravenous Catheter|PROCEDURE: Transcranial Doppler Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study to Assess the Efficacy & Safety of Gemcitabine + Nab Paclitaxel With or Without Dociparstat in Metastatic Pancreatic Cancer Patients
Status: TERMINATED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|DRUG: Dociparstat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Papilloma Virus (HPV) Self-collection and Women Adherence
Status: UNKNOWN
Conditions: Cervical Cancer|HPV Infection
Interventions: DIAGNOSTIC_TEST: CERVICAL HPV|DIAGNOSTIC_TEST: SELF SAMPLING HPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase 1 Protocol of 5-Azacytidine and Erlotinib in Advanced Solid Tumor Malignancies
Status: COMPLETED
Conditions: Advanced Solid Tumor Malignancies
Interventions: DRUG: 5-azacytidine, erlotinib|DRUG: Erlotinib PO and Vidaza IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Drivers of Mobility Resilience: The Dopaminergic System - Placebo-Controlled Arm
Status: COMPLETED
Conditions: Parkinsonian Signs in Older Persons
Interventions: DRUG: Carbidopa 25 mg|DRUG: Carbidopa-Levodopa 25/100 mg|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-Drug Interaction Between Colchicine and Ritonavir
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine|DRUG: Ritonavir|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo
Status: ACTIVE_NOT_RECRUITING
Conditions: Monkeypox Virus Infection
Interventions: BIOLOGICAL: JYNNEOS (Liquid Formulation)|BIOLOGICAL: JYNNEOS (Lyophilized Formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Healthy Subjects to Assess the Effect of LY450139 on Amyloid Beta Peptide Production Rate and or Dose Response.
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: LY450139|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Stress Management Intervention in Inner City Adolescents With Asthma
Status: UNKNOWN
Conditions: Asthma|Psychosocial Stress
Interventions: BEHAVIORAL: Stress management program|OTHER: Peer viewed movies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Staccato Alprazolam and Photoparoxysmal Response
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: A=Placebo|DRUG: B=Inhaled Alprazolam 0.5 mg|DRUG: C=Inhaled Alprazolam 1 m|DRUG: D= Inhaled Alprazolam 2 mg|DRUG: E=Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Right Question Project (RQP) Health Education Strategy in a Mental Health Setting
Status: COMPLETED
Conditions: Diagnosis, Psychiatric
Interventions: BEHAVIORAL: RQP patient health education module
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Discontinuation of Levothyroxine Therapy for Patients With Subclinical Hypothyroidism
Status: COMPLETED
Conditions: Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Brief Marijuana Interventions With a Behavioral Economic Supplement
Status: COMPLETED
Conditions: Marijuana Use
Interventions: BEHAVIORAL: Brief Motivational Intervention (BMI)|BEHAVIORAL: Substance-Free Activity Session (SFAS)|BEHAVIORAL: Relaxation Session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Structural and Functional Evaluation of the Visual Pathway
Status: UNKNOWN
Conditions: Pituitary Adenoma|Visual Impairment|Sellar Tumor|Neuroimaging
Interventions: DIAGNOSTIC_TEST: resting state fMRI|DIAGNOSTIC_TEST: visual tasking state fMRI|DIAGNOSTIC_TEST: diffusion tensor imaging|DIAGNOSTIC_TEST: automated visual field|DIAGNOSTIC_TEST: visual acuity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pacritinib for Patients With Lower-Risk Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Pacritinib|DRUG: 5-azacitidine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 2 Different Regimens of Tetravalent Ad26.Mos4.HIV Prime Followed by Boost With Modified Vaccinia Ankara (MVA)-Mosaic OR Ad26.Mos4.HIV Plus a Combination of Mosaic and Clade C gp140 Protein in Human Immunodeficiency Virus (HIV) Type 1 Infected Adults on Suppressive Antiretroviral Treatment
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: BIOLOGICAL: Ad26.Mos4.HIV|BIOLOGICAL: MVA-Mosaic|BIOLOGICAL: Clade C gp140 + Mosaic gp140|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Quantifying the Impact of the Peanut Ball on the Duration of the Active Stage of Labor
Status: UNKNOWN
Conditions: Labor Onset and Length Abnormalities|Prolonged Labor|Labor Long|Labor; Poor
Interventions: DEVICE: Positioning with peanut ball|OTHER: Traditional positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of a Printed Decision Aid on Cataract Surgery Choice
Status: UNKNOWN
Conditions: Age Related Cataracts
Interventions: OTHER: A decision aid booklet about cataract surgery choice|OTHER: An usual booklet about cataract and cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Corticosteroid Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Status: TERMINATED
Conditions: Chronic Rhinosinusitis Without Nasal Polyps
Interventions: DRUG: Prednisone|DRUG: Topical mometasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Management of Periappendicular Abscess
Status: COMPLETED
Conditions: Appendicitis|Abdominal Abscess
Interventions: PROCEDURE: Laparoscopic appendectomy|PROCEDURE: Conservative management with percutaneous drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nexpowder Application to Prevent Delayed Bleeding After Colorectal Endoscopic Mucosal Resection
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DEVICE: Endoscopic mucosal resection with nexpowder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT