pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Mepolizumab as Add-on Treatment IN Participants With COPD Characterized by Frequent Exacerbations and Eosinophil Level
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Placebo|BIOLOGICAL: Mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Optimizing Research of Lamivudine Therapy
Status: COMPLETED
Conditions: Compensated Chronic Hepatitis B
Interventions: DRUG: lamivudine|DRUG: lamivudine|DRUG: lamivudine, adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP)
Status: RECRUITING
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Anodal tDCS combined with active physiotherapy|DEVICE: Sham anodal tDCS combined with active physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Study of Nivolumab Compared to Sorafenib as a First Treatment in Patients With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Functional Training on Field Hockey Players Physical Fitness, Hockey Skills and Functional Movement
Status: COMPLETED
Conditions: Physical Inactivity
Interventions: OTHER: Functional training|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Financial Toxicity and Quality of Life in Patients With TGCT
Status: RECRUITING
Conditions: Testicular Neoplasm
Interventions: OTHER: Comprehensive Score for financial toxicity (COST)|OTHER: Functional Assessment of Cancer Therapy: General (FACT-G)|OTHER: EORTC QLQ C-30|OTHER: EORTC QLQ-TC26.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanisms of Impaired HIV-associated B Cell and Pneumococcal Vaccine Responses
Status: UNKNOWN
Conditions: HIV|Pneumococcal Infections|Pneumococcal Vaccines
Interventions: BIOLOGICAL: PCV-13|BIOLOGICAL: PPSV-23
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase III Study of Camrelizumab in Combination With Chemotherapy in Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Camrelizumab|DRUG: Placebos|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Silicone Oil Tamponade for Vitrectomy of Hypermyopic Foveoschisis.
Status: RECRUITING
Conditions: Hypermyopic Foveoschisis
Interventions: PROCEDURE: PPV with SO tamponade|PROCEDURE: PPV with fovea-sparing ILMP and gas tamponade|PROCEDURE: PPV with gas tamponade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Management of Metabolic Bone Disease in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Skeletal Anomalies|Kidney Transplant; Complications
Interventions: DIAGNOSTIC_TEST: measurements to evaluate metabolic bone disease|DIAGNOSTIC_TEST: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray
Status: TERMINATED
Conditions: Motion Sickness
Interventions: DRUG: Scopolamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Triflusal on Cognitive Functions in Subjects Under Chronic Stress
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Triflusal|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis
Status: COMPLETED
Conditions: Periodontitis Chronic Generalized Moderate
Interventions: DRUG: Cymbopogon citratus (lemongrass) oil gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: MK-8892|DRUG: Placebo for MK-8892
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Repeat-Dose Rifampin on the Pharmacokinetics (PK) of PF-06651600
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-06651600|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Bioavailability Study of Aripiprazole 10 mg Oral Soluble Film vs Abilify® 10 mg Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders
Status: WITHDRAWN
Conditions: Stem Cell Transplantation
Interventions: DRUG: Fludarabine|DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Bortezomib|DRUG: Rituximab|DRUG: Busulfan|DRUG: Cyclophosphamide (Cy)|DRUG: Tacrolimus (or cyclosporine)|DRUG: Mycophenolate mofetil (MMF)|DRUG: Rabbit ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Test the Growth-Promoting Effect of Fortified Spreads When Used as Complementary Food for Infants
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: fortified spread (RUTF)|DIETARY_SUPPLEMENT: maize and soy flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Integrative and Complementary Health Practices (PICS)
Status: RECRUITING
Conditions: Neoplasms|Epilepsy
Interventions: OTHER: Without laying on of hands subgroup|OTHER: Laying on of hands without Spiritual connection|OTHER: Laying on of hands by Spiritual "Passe"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy
Status: RECRUITING
Conditions: Congenital Cataract
Interventions: PROCEDURE: PCCC procedure without A-vit|PROCEDURE: PCCC+A-Vit procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of Pre-operative Use of 3D Printing for Endovascular Treatment of Unruptured Intracranial Aneurysms With Intrasaccular Flow Disruptor
Status: NOT_YET_RECRUITING
Conditions: Intracranial Aneurysm
Interventions: PROCEDURE: 3D anatomical model of aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exploring the Psychophysics of Keratoconus Using the Moorfields Acuity Chart
Status: COMPLETED
Conditions: Keratoconic Subjects
Interventions: DEVICE: Moorfields Acuity Chart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Baricitinib (LY3009104) in Participants From 2 Years to Less Than 18 Years Old With Active JIA-Associated Uveitis or Chronic Anterior Antinuclear Antibody-Positive Uveitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Uveitis
Interventions: DRUG: Baricitinib|DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) and Virtual Reality Task in Parkinson Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: tDCS-active|DEVICE: tDCS-sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study to Evaluate the Efficacy and Safety of MEDI8852 in Adults Who Are Hospitalized With Type A Influenza.
Status: WITHDRAWN
Conditions: Influenza - Type A Strains
Interventions: DRUG: Oseltamivir|DRUG: MEDI8852|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IP ALT-803 Followed by SQ ALT-803 for Ovarian Cancer
Status: COMPLETED
Conditions: FIGO Stage III and IV Ovarian Cancer|FIGO Stage III and IV Fallopian Tube Cancer|FIGO Stage III Primary Peritoneal Cancer
Interventions: BIOLOGICAL: ALT-803 Subcutaneous|BIOLOGICAL: ALT-803 Intraperitoneal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soy-Ready to Use Therapeutic Food (RUTF) in Severely Malnourished Children
Status: COMPLETED
Conditions: Severe Acute Malnutrition|Severe Wasting|Community Based Nutritional Management
Interventions: DIETARY_SUPPLEMENT: Soy-based RUTF (in double blind design)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Plasma and Platelet microRNAs in Clopidogrel Low Response Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: acetylsalicylic acid (ASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tier - Palliative Care For Patients With Advanced Heart Failure or Cancer
Status: RECRUITING
Conditions: Advanced Heart Failure|Advanced Non-colorectal Gastro-intestinal Cancer|Advanced Lung Cancer
Interventions: BEHAVIORAL: Tier - Palliative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy For Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rosiglitazone Extended Release 2mg|DRUG: Rosiglitazone Extended Release 8mg|OTHER: Placebo|OTHER: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of an ERAS Protocol in Gynecological Surgery
Status: COMPLETED
Conditions: Surgery|Hysterectomy|Gynecologic Disease|Gynecologic Cancer|Anesthesia
Interventions: OTHER: Changes in preoperative care|OTHER: Changes in intraoperative care|OTHER: Changes in postoperative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Medium Cut-Off Hemodialysis on Protein Energy Wasting: The EMCOPEW Study
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease (ESRD)
Interventions: OTHER: Hemodialysis sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Psychological Intervention For Brain Tumor Caregivers
Status: COMPLETED
Conditions: Malignant Glioma|Anxiety|Caregiver Burden|Malignant Brain Tumor
Interventions: BEHAVIORAL: Psychosocial Intervention Group|BEHAVIORAL: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of Shared Decision-Making With Decision Aids on Acoustic Neuroma Treatment Choice: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Neuroma, Acoustic
Interventions: OTHER: Decision aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Effectiveness of Family DSMES and Standard DSMES Among Diverse Populations
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Family Diabetes Self-Management Education and Support|BEHAVIORAL: Standard Diabetes Self-Management Education and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endovascular Aortic Repair for Aortic Dissection
Status: UNKNOWN
Conditions: Aorta Dissection|Aorta Aneurysm
Interventions: DEVICE: Stent Graft (Medtronic, Microport, Ankura)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remifentanil on Cardiac Function in Patients With Diastolic Dysfunction
Status: UNKNOWN
Conditions: Diastolic Dysfunction
Interventions: DRUG: Remifentanil 2 MG|DIAGNOSTIC_TEST: Echocardiographic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Systemic VEGF Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Visual Impairment Due to Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Hypothermia to Treat Neonatal Hypoxic-Ischemic Encephalopathy
Status: COMPLETED
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: DEVICE: Cooling cap (YJW608-04B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety,Tolerability,Pharmacodynamics & Pharmacokinetics of JTE-451 in Active Plaque Psoriasis Subjects
Status: COMPLETED
Conditions: Plaque Psoriasis|Psoriasis|Skin Diseases
Interventions: DRUG: JTE-451|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy of Sclerotomy Sites for Prevention of Late Postvitrectomy Diabetic Hemorrhage
Status: COMPLETED
Conditions: Late Postvitrectomy Diabetic Hemorrhage.
Interventions: PROCEDURE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetics and Acceptability of PC-1005 for Vaginal Use
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: PC-1005|DRUG: HEC gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3192767 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3192767|DRUG: Basal Insulin Peglispro|DRUG: Insulin Glargine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Termination of Early Pregnancy in Scarred Uterus With Lletrozole and Misoprostol Compared to Misoprostol Alone
Status: UNKNOWN
Conditions: Termination of Early Pregnancy in Scarred Uterus
Interventions: DRUG: Letrozole 2.5mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Characterise the Physiology of Weight Loss and Regain Under Dietary, Behavioural and Pharmacological Interventions in Healthy Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: sibutramine|OTHER: sibutramine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Platform Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With aOX40 (GSK3174998) in Participants With RRMM
Status: TERMINATED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Belantamab Mafodotin|DRUG: GSK3174998
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Chronic Knee Pain
Interventions: DRUG: 6% aqueous phenol|DRUG: MethylPREDNISolone 40 MG|DRUG: Intraarticular Knee Placebo|DRUG: Genicular Nerve Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastric Electrical Stimulation (GES) and Pyloroplasty for the Treatment of Gastroparesis
Status: RECRUITING
Conditions: Gastroparesis
Interventions: DEVICE: Gastric Electrical Stimulation (GES) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fermented and Non-fermented Soy Based Food in Appetite and Satiety Biomarker Among Young Obesity
Status: COMPLETED
Conditions: Obesity, Abdominal|Weight Loss
Interventions: BEHAVIORAL: meal test response
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: AZD8055 for Adults With Recurrent Gliomas
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Malignant Glioma|Brainstem Glioma
Interventions: DRUG: AZD8055
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Bexxar in Relapsed/Refractory DLCL
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Bexxar|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Potassium Iodide (KI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GAit, MEmory, Dietary and Vitamin D
Status: COMPLETED
Conditions: Memory Complaint Without Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Yogurt supplemented with vitamin D and calcium|DIETARY_SUPPLEMENT: Yogurt not supplemented with vitamin D and calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)
Status: COMPLETED
Conditions: Amnestic Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DRUG: Insulin (Humulin® R U-100)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of BMS-986165 in Participants With Normal Liver Function and Participants With Mild to Severe Liver Damage
Status: COMPLETED
Conditions: Liver Dysfunction|Healthy Volunteers
Interventions: DRUG: BMS-986165
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Motor and Cognitive Training in Pre-frail Elderly
Status: RECRUITING
Conditions: Pre-frail Elderly
Interventions: DEVICE: combined motor and cognitive training|DEVICE: motor training alone|DEVICE: cognitive training alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Approach to Resection of Glioblastoma (GBM) by 5-Aminolevulinic Acid (5-ALA) and Intraoperative Magnetic Resonance Imaging (MRI)
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: PROCEDURE: diagnostic 5-ALA and MRI for tumor resection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Healing Potentiality of Trypsin and Alpha Chemo Trypsin in Mandibular Molars With Chronic Apical Abscess
Status: NOT_YET_RECRUITING
Conditions: Mandibular Abscess
Interventions: DRUG: Alphintern® , tablet, Amoun, Egypt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optic Nerve Head Structural Response to IOP Elevation in Patients With Keratoconus
Status: RECRUITING
Conditions: Keratoconus|Glaucoma
Interventions: DEVICE: Ophthalmodynamometer|DEVICE: Goldmann applanation tonometer|DEVICE: Pentacam|DEVICE: ORA|DEVICE: Optical Coherence Tomography (OCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Status: RECRUITING
Conditions: Aortic Dissection|Aortic Aneurysm|Intramural Hematoma|Penetrating Aortic Ulcer
Interventions: DEVICE: NEXUS Aortic Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin
Status: COMPLETED
Conditions: Complications of Diabetes Mellitus|Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Diacerein|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Lapatinib in Combination With Oxaliplatin and Capecitabine in Subjects With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Neoplasms, Colorectal
Interventions: DRUG: lapatinib|DRUG: oxaliplatin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GP Chemotherapy in Combination With Anti-PD-1 and Anti-TIGIT in Unresectable Advanced BTC
Status: ACTIVE_NOT_RECRUITING
Conditions: Biliary Tract Carcinoma
Interventions: DRUG: GP+PD-1+Tight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hookworm Therapy for Coeliac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: OTHER: Gluten micro-challenge|OTHER: Inadvertent gluten challenge|OTHER: Moderate gluten challenge|OTHER: Liberal diet|OTHER: Necator americanus-hookworm larvae L3-10|OTHER: Tabasco® Sauce|OTHER: Necator americanus-hookworm larvae L3-20|OTHER: Gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega-3/Omega-6 Fatty Acids for Attention-Deficit/Hyperactivity Disorder (ADHD): A Trial in Children and Adolescents
Status: COMPLETED
Conditions: ADHD|Reading/Writing Disorder
Interventions: DIETARY_SUPPLEMENT: Omega 3/6 fatty acids|DIETARY_SUPPLEMENT: Placebo (olive oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STOPFLU: Is it Possible to Reduce the Number of Days Off in Office Work by Improved Hand-hygiene?
Status: COMPLETED
Conditions: Respiratory Infection|Gastroenteritis
Interventions: BEHAVIORAL: Hand washing|BEHAVIORAL: Disinfectant rubbing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Dantrolene to Improve Analgesia in Posterior Lumbar Surgery
Status: COMPLETED
Conditions: Lumbar Spine Injury
Interventions: DRUG: Dantrolene|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a DASH-Style Diet on Urinary Risk Factors for Kidney Stone Disease
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: OTHER: DASH-Style Diet|OTHER: Western-Style Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Palatability Testing of a New Paediatric Formulation of Valacyclovir
Status: COMPLETED
Conditions: Varicella Zoster Virus Infection|Herpes Simplex Virus Infection
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Titan Versus Everolimus Intracoronary Stent (Xience V) in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus|Percutaneous Coronary Intervention
Interventions: DEVICE: Titanium bare metal stent (Titan2®)|DEVICE: Everolimus Drug Eluting Stent (Xience-V®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Nitisinone Formulations Compared to Orfadin
Status: COMPLETED
Conditions: Hereditary Tyrosinemia, Type I
Interventions: DRUG: Nitisinone|DRUG: Nitisinone 10 mg Tablet High Compritol|DRUG: Orfadin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents Versus Everolimus-Eluting Stents in Coronary Artery Disease Patients With Diabetes Mellitus Global
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DEVICE: Abluminus DES+ Sirolimus Eluting Stent System (SES)|DEVICE: XIENCE Everolimus Eluting Coronary Stent System (XIENCE family)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Alveolar Ridge Preservation With Layered Collagen and Xenograft
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Ridge Preservation
Interventions: PROCEDURE: deep collagen layer, xenograft and collagen membrane|PROCEDURE: xenograft and collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of HUK in Acute Stroke Patients: MRS and CTP
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Human urinary kallidinogenase (HUK)|DRUG: aspirin® , clopidogrel® , atorvastatin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic Encephalopathy
Status: TERMINATED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: sodium phenylacetate and sodium benzoate injection 10% / 10%|DRUG: sodium phenylacetate and sodium benzoate injection 10% / 10%|DRUG: placebo solution (10% dextrose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Efficacy of Full-time Occlusion Therapy in Severe Amblyopia at Different Ages
Status: UNKNOWN
Conditions: Amblyopia|Strabismus
Interventions: DEVICE: Occlusion therapy by Eye Patch|DEVICE: Occlusion therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients
Status: UNKNOWN
Conditions: Retinitis Pigmentosa|Retinal Degeneration|Cannabis
Interventions: DRUG: cannabis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)
Status: RECRUITING
Conditions: Metastatic Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: Darolutamide (BAY1841788)|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Toric Intraocular Lenses for Treating Corneal Astigmatism in Patients With Cataract and Previous DALK
Status: COMPLETED
Conditions: Corneal Astigmatism in Cataract Patients and Previous DALK
Interventions: DEVICE: Customized toric IOL for post-DALK atigmatism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uroflow Measurement With Electromyography (EMG) to Identify Lower Urinary Tract Symptoms (LUTS): Conducted on Healthy Children
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Urologic Diseases
Interventions: DIAGNOSTIC_TEST: Uroflow|DIAGNOSTIC_TEST: Uroflow/EMG|DIAGNOSTIC_TEST: US
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short-Delay Cord Clamping Compared to Extended- Delay Cord Clamping in Term Neonates That Require Resuscitation.
Status: COMPLETED
Conditions: Placental Transfusion
Interventions: PROCEDURE: Short Delay Cord Clamping|PROCEDURE: Extended Delay Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Carcinoid Syndrome
Interventions: DRUG: Sandostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Automatic Real-time Diagnosis of Gastric Mucosal Disease Using pCLE With Artificial Intelligence
Status: COMPLETED
Conditions: Gastric Diseases|Artificial Intelligence|Confocal Laser Endomicroscopy
Interventions: DIAGNOSTIC_TEST: The diagnosis of Artificial Intelligence and endoscopist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of Wagner 2 DFUs
Status: TERMINATED
Conditions: Diabetic Foot
Interventions: BIOLOGICAL: SkinTE|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Alone Versus Combined With Intravitreal Bevacizumab for Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare Time to Response in the Symptoms of Anxiety to Concomitant Treatment With Niravam™ and an SSRI or SNRI to Treatment With an SSRI or SNRI Alone in Subjects With Generalized Anxiety Disorder or Panic Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|Panic Disorder
Interventions: DRUG: Niravam|DRUG: SSRI/SNRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy in Men With Low Testosterone Levels and Metabolic Syndrome or Early Stages of Type 2 Diabetes
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DRUG: Transdermal testosterone therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Ventilation of Obese Patients During Oral Surgical Procedures
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: low PEEP|PROCEDURE: ARM|PROCEDURE: high PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ferumoxytol in Magnetic Resonance Imaging of Pediatric Patients With Brain Tumors
Status: WITHDRAWN
Conditions: Brain Neoplasm
Interventions: DRUG: Ferumoxytol|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of the ToothWave Power Toothbrush for Extrinsic Stain Reduction
Status: COMPLETED
Conditions: Tooth Discoloration
Interventions: DEVICE: ToothWave|DEVICE: powered toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SARS-CoV-2 Antibodies Based IVIG Therapy for COVID-19 Patients
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 antibody based IVIG therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: This Study Tests BI 1467335 in Healthy Male Volunteers. The Study Tests How Different Doses of BI 1467335 Are Taken up and Handled by the Body
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]BI 1467335|DRUG: BI 1467335
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Clinically Occult Glioma Cells and Characterization of Glioma Behavior Through Machine Learning Analysis of Advanced Imaging Technology
Status: UNKNOWN
Conditions: Glioma
Interventions: PROCEDURE: MRS Imaging|PROCEDURE: PET Scanning|PROCEDURE: Diffusion Tensor Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CYTALUX™for the Intraoperative Imaging of Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Cytalux™ (pafolacianine) for fluorescent imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prediction Model of Occult Omental Metastasis in Patients With Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Omental Metastasis
Interventions: OTHER: Without any intervention, we only divided gastric cancer patients into two groups based on postoperative pathology, and analyzed their basic characteristics and risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Verapamil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II A Trial of Curcumin Among Patients With Prevalent Subclinical Neoplastic Lesions (Aberrant Crypt Foci)
Status: COMPLETED
Conditions: Healthy, no Evidence of Disease|Tobacco Use Disorder
Interventions: OTHER: laboratory biomarker analysis|OTHER: pharmacological study|DRUG: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: By Pass Surgery With Stem Cell Therapy in Chronic Ischemic Cardiopathy
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: PROCEDURE: Autologous bone marrow derived stem cells myocardial transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
Status: COMPLETED
Conditions: Major Depressive Disorder|Bipolar Disorder
Interventions: OTHER: chronobiological augmentation|DRUG: sertraline, lithium|RADIATION: one night of sleep deprivation and two FDG PET scans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block to Treat Long COVID 19 Case Series
Status: COMPLETED
Conditions: Long COVID|Long Covid19|Post-COVID-19 Syndrome|Post Acute COVID-19 Syndrome|Dysautonomia|Anosmia|Dysgeusia|Brain Fog|Muscle Pain|Shortness of Breath|Dizziness|Fatigue Post Viral|Cough|Menstrual Cycle Abnormal|Pain
Interventions: PROCEDURE: Stellate Ganglion Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Adult Patients With Brain Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Glutamine on Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DIETARY_SUPPLEMENT: glutamine supplementation|DIETARY_SUPPLEMENT: fantomalt supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Atrial Fibrillation Study in Patients Undergoing Coronary Artery Bypass Grafting. (RASCABG 1 Study)
Status: COMPLETED
Conditions: Atrial Fibrillation|Coronary Artery Bypass Grafting
Interventions: DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Assessing the Safety, Immune Response, and Early Efficacy of a Candida Vaccine in Women With Recurrent Vulvovaginal Candidiasis: A Randomized Controlled Study
Status: RECRUITING
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: BIOLOGICAL: Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Individual Psychosocial Interventions for Cancer Patients
Status: COMPLETED
Conditions: Advanced Solid Tumor Diseases
Interventions: BEHAVIORAL: Individual Meaning-Centered Psychotherapy (IMCP)|BEHAVIORAL: standard Individual Supportive Psychotherapy (ISP)|BEHAVIORAL: enhanced usual care (EUC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previously Enrolled in A536-04 (A536-06/MK-6143-004)
Status: COMPLETED
Conditions: β-Thalassemia
Interventions: DRUG: luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL
Status: COMPLETED
Conditions: Small Lymphocytic Lymphoma|CLL (Chronic Lymphocytic Leukemia)
Interventions: DRUG: Fludarabine Phosphate|BIOLOGICAL: Ofatumumab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Pharmacokinetics (PK) of Single Intravenous (IV) Dose of Vedolizumab 300 Milligram (mg) in Healthy Adult Chinese Participants
Status: COMPLETED
Conditions: Colitis, Ulcerative|Crohn Disease
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cohort Study of Risk Reducing Salpingectomy
Status: COMPLETED
Conditions: Sterilization, Tubal|Salpingectomy|Ovary|Prevention & Control
Interventions: PROCEDURE: Salpingectomy|PROCEDURE: Traditional sterilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3321367 Alone or With LY3300054 in Participants With Advanced Relapsed/Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: LY3321367|DRUG: LY3300054
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Infusion or Quadratus Lumborum Block and Intrathecal Morphine, Versus Intrathecal Morphine Alone
Status: TERMINATED
Conditions: Gynecologic Cancer
Interventions: DRUG: Lidocaine Bolus Infusion|PROCEDURE: QL block|DRUG: Saline Bolus Infusion|PROCEDURE: Simulated QL block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Thought Field Therapy (TFT) be Helpful for Patients With an Anxiety Disorder?
Status: COMPLETED
Conditions: Agoraphobia|Social Phobia|PTSD
Interventions: BEHAVIORAL: Thought Field Therapy (TFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry
Status: NOT_YET_RECRUITING
Conditions: Chronic Heart Failure|Fluid Overload|Acute Decompensated Heart Failure|Edema
Interventions: DEVICE: AquaPass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib, Fludarabine Phosphate, Cyclophosphamide, and Obinutuzumab in Treating Patients With Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|DRUG: Ibrutinib|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients With Tuberculosis (ANRS129)
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: efavirenz|DRUG: tenofovir DF|DRUG: emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Coconut Oil With Peppermint Essential for Oral Hygiene Routine
Status: RECRUITING
Conditions: Fluoride Adverse Reaction
Interventions: OTHER: AVIVA-PURE-CocoPull-Organic-made in USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Pirfenidone in CTD-ILD
Status: RECRUITING
Conditions: Pirfenidone|Connective Tissue Diseases|Interstitial Lung Disease
Interventions: DRUG: Pirfenidone|DRUG: glucocorticoid and immunosuppressant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Hyperandrogenism in Normal and Excessive Body Weight Adolescent Girls and Their Relation to Diet (HAstudy)
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Lifestyle intervention|OTHER: Effects of AIDiet intervention to improve diet quality, immuno-metabolic health in normal and overweight PCOS girls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ammonia N-13 Myocardial Blood Flow Absolute Quantification by PET in Patients With Known or Suspected CAD (Ammonia MAP)
Status: COMPLETED
Conditions: Myocardial Ischemia|Coronary Disease|Coronary Artery Disease|Heart Diseases|Cardiovascular Diseases|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases
Interventions: DIAGNOSTIC_TEST: Myocardial Perfusion Imaging Study|DRUG: AMMONIA N-13 37.5 mCi in 1 mL INTRAVENOUS INJECTION [Ammonia N 13]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study To Evaluate The Effect Of Multiple Doses of CTP-543 On The Pharmacokinetics Of Single Doses of Midazolam In Healthy Subjects
Status: COMPLETED
Conditions: Health Volunteers
Interventions: DRUG: Midazolam|DRUG: CTP-543
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER