pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: IRB-HSR# 14299: The Use of the Intrathoracic Pressure Regulator (ITPR) to Improve Cerebral Perfusion Pressure in Patients With Altered Intracranial Elastance
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: DEVICE: ITPR -5 mm Hg then -9 mm Hg|DEVICE: ITPR -9 & then -5mm Hg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Betalains on Cardiovascular Health and Quality of Life
Status: RECRUITING
Conditions: Vascular Stiffness|Vasodilation|Sleep|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Betalains|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized Trial for Patients With Platinum Resistant Ovarian, Fallopian or Primary Peritoneal Cancer.
Status: COMPLETED
Conditions: Genital Neoplasms, Female|Fallopian Tube Neoplasms|Ovarian Neoplasms|Pelvic Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single & Multiple Ascending Dose Study of SAR443820 in Healthy Adult Participants
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (Healthy Volunteers)
Interventions: DRUG: SAR443820|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anecortave Acetate in Patients With Exudative Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 30 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/mL|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of Hepatitis B, C and D and HIV Along the Maroni River Bordering French Guiana and Suriname (MaHeVi)
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis C|Hepatitis D|HIV Infections|Prevalence|Epidemiology
Interventions: OTHER: Questionnaire|OTHER: Biocollection|OTHER: Delivery of results|OTHER: Results and advices on transmission prevention methods|OTHER: Confirmation of results on a blood test (In the event of a positive result)|OTHER: Information for care|OTHER: Monitoring and treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Accuracy of Implant Placement for Patients With Mandibular Reconstruction Using Dynamic Navigation and Static Guides
Status: NOT_YET_RECRUITING
Conditions: Mandibular Deficiency
Interventions: PROCEDURE: The guidance of dynamic navigation|PROCEDURE: The guidance of static template
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interviewing Technique on Smoking Urge and Smoking Cessation Success in Teachers
Status: COMPLETED
Conditions: Smoking|Motivational Interviewing|School Health|Nursing
Interventions: BEHAVIORAL: MOTIVATIONAL INTERVIEWING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Food Matrix Effect on Flavanol Absorption, Metabolism and Excretion: Methylxanthines
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: CF Control|OTHER: CF-Theobromine|OTHER: CF-Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of the Effectiveness of Proprioceptive Neuromuscular Facilitation Techniques in Text Neck Syndrome
Status: COMPLETED
Conditions: Neck Muscle Issue
Interventions: OTHER: Exercise program including active cervical range of motion, strengthening, and posture correction exercises and ergonomic modifications|OTHER: PNF exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning Transplant Using Haploidentical Donors
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Myelofibrosis|CMML|Multiple Myeloma
Interventions: DRUG: Fludarabine|DRUG: Melphalan|DRUG: Cyclophosphamide|PROCEDURE: peripheral blood stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Optimized BNCT for Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer|Squamous Cell Carcinoma
Interventions: RADIATION: Accelerator-based BNCT with borofalan(10B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis
Status: NOT_YET_RECRUITING
Conditions: Allogeneic Disease|GVHD,Acute|Graft Failure
Interventions: BIOLOGICAL: WJ-MSC infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Diagnostic and Prognostic Role of PET (PET/CT and PET/MRI) in Gynecological Tumors.
Status: RECRUITING
Conditions: Gynecological Tumors
Interventions: DIAGNOSTIC_TEST: the diagnostic and prognostic value of PET/MRI and PET/CT with 18F-FDG in patients presenting with gynecological tumors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability and Pharmacokinetics of KX826 in Healthy Male Subjects With Androgenetic Alopecia Following Topical Single Ascending Dose Administration
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: KX0826|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Realistic Computational Electrophysiology Simulations for the Targetted Treatment of Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Atrial cardiac magnetic resonance imaging|DIAGNOSTIC_TEST: Atrial electro-anatomic mapping|OTHER: Atrial fibrillation symptom questionnaire|DIAGNOSTIC_TEST: Patch-based 2 week ambulatory monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Attenuation Correction Accuracy in Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI)
Status: TERMINATED
Conditions: PET/CT
Interventions: DEVICE: Positron Emission Tomography-Magnetic Resonance Imaging (PET-MRI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Mesenchymal Stem Cells and Spinal Fusion
Status: COMPLETED
Conditions: Lumbar Spondylolisthesis Involving L4-L5, and/or|Degenerative Discopathy Involving L4-L5
Interventions: BIOLOGICAL: XCEL-MT-OSTEO-ALPHA|PROCEDURE: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine as Adjuvant for Bupivacaine in Ultrasound Guided Infraorbital Nerve Block for Cleft Lip Repair
Status: COMPLETED
Conditions: Cleft Lip
Interventions: DRUG: Dexmedetomidine group|DRUG: Dexamethasone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stepped vs Stratified Care for Pediatric Anxiety Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Internet-delivered cognitive behavioral therapy (ICBT)|BEHAVIORAL: In-person cognitive behavioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Perioperative Adiponectin and Postoperative Inflammatory Response After Major Abdominal Surgery
Status: RECRUITING
Conditions: Obesity, Abdominal|Surgery|Systemic Inflammatory Response Syndrome|Postoperative Complications
Interventions: DIAGNOSTIC_TEST: serum levels of adiponectin|DIAGNOSTIC_TEST: IL-6|OTHER: Postoperative systemic infflamation|OTHER: Postoperative complications
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Low Intensity Ultrasound Therapy on Chronic Pain Due to Osteoarthritis of the Knee.
Status: UNKNOWN
Conditions: Osteoarthritis in the Knee
Interventions: PROCEDURE: Low Intensity Ultrasound Therapy|OTHER: Enhancing CBD oil penetration into joints by sonophresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RHPRG4 FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD)
Status: NOT_YET_RECRUITING
Conditions: Ocular Graft-versus-host Disease
Interventions: DRUG: rhPRG4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 403 in Subjects With Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: AMG 403|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Trivalent Recombinant Hemagglutinin Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Vaccine, recombinant Hemagglutinin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early IntraVenous Administration of Nutritional Support
Status: UNKNOWN
Conditions: Cancer of Stomach|GastroEsophageal Cancer
Interventions: OTHER: Nutritional counseling alone|OTHER: Early supplemental parenteral nutrition plus nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness and Safety of BiSAAE for Resistant Hypertension.
Status: NOT_YET_RECRUITING
Conditions: Resistant Hypertension
Interventions: PROCEDURE: BiSAAE|PROCEDURE: traditional triple antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Sickle-Cell Disease With Crisis
Interventions: GENETIC: Drug Product is administered by IV infusion following myeloablative conditioning with busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hot Flash and Night Sweat Virtual Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: Bonafide-HF3.0|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Eight-week RCT of Home-based Pilates for Symptoms of Anxiety, Depression, and Fatigue Among People With MS
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Home-based Pilates|OTHER: Delayed-start Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Natural Versus Programmed Frozen Embryo Transfer (NatPro)
Status: RECRUITING
Conditions: Pregnancy Related|Pre-Eclampsia
Interventions: PROCEDURE: Modified natural cycle|PROCEDURE: Programmed cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stellate Ganglion Block
Status: NOT_YET_RECRUITING
Conditions: Esophagectomy|Pneumonectomy|Lobectomy
Interventions: DRUG: 0.5% bupivacaine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination of Terbutaline and Danazol as the Treatment of Corticosteroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Terbutaline|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does BRV Have Faster Onset Time & Greater Effect Than LEV in Epilepsy Pts Using PPR Pharmacodynamic Efficacy Endpoint
Status: COMPLETED
Conditions: Photosensitive Epilepsy
Interventions: DRUG: BRV vs LEV in randomized double blinded, crossover fashion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of YYB101 With Irinotecan, Patients Who Are Metastatic or Recurrent Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic|Colorectal Cancer Recurrent
Interventions: DRUG: YYB101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosol Cyclosporine in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Cyclosporine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metastasis-directed Therapy in Oligoprogressive Castration-refractory Prostate Cancer
Status: RECRUITING
Conditions: Castration-resistant Prostate Cancer|Oligoprogressive
Interventions: RADIATION: Radiotherapy|PROCEDURE: metastasectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Colesevelam Hydrochloride|DRUG: Ezetimibe|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Foods Within a Meal and Food Liking Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Diet Habit|Obesity
Interventions: BEHAVIORAL: Order 1|BEHAVIORAL: Order 2|BEHAVIORAL: Order 3|BEHAVIORAL: Order 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Developing a New, Dynamic, Therapeutic Pacemaker Algorithm for Stabilising Periodic Breathing in Chronic Heart Failure.
Status: UNKNOWN
Conditions: Periodic Breathing
Interventions: DEVICE: Pacemaker manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rifapentine Plus Moxifloxacin for Treatment of Pulmonary Tuberculosis
Status: TERMINATED
Conditions: Tuberculosis
Interventions: DRUG: Rifapentine, Moxifloxacin, Pyrazinamide, Isoniazid|DRUG: Isoniazid, Rifampin, Pyrazinamide, Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zithromax EV in Community-Acquired Pneumonia (CAP)
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Azithromycin|DRUG: Ampicillin/sulbactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of the Commercially Available Medtronic Resolute Integrity Zotarolimus-Eluting Coronary Stent System
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Resolute Integrity Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Endocrinologists Health Education Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Intensive training for endocrinologists in T2DM management|OTHER: Regular training for endocrinologists in T2DM management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Cisplatin, and Radiation Therapy in Treating Patients With Locally Advanced Esophageal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: Docetaxel and Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery
Status: COMPLETED
Conditions: Postoperative Pain Management
Interventions: DRUG: Morphine Sulfate|DRUG: Intravenous paracetamol|DRUG: Intravenous ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of STI-5656 (Abivertinib Maleate) in Subjects Hospitalized With COVID-19
Status: COMPLETED
Conditions: Covid-19
Interventions: DRUG: Abivertinib|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety of Allogeneic Umbilical Cord Blood Infusions in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: sibling umbilical cord blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Switching From Twice Daily Tacrolimus To Once Daily Formulation On Cardiovascular Risk
Status: COMPLETED
Conditions: Immunosuppression|Cardiovascular Diseases|Kidney Transplantation
Interventions: DRUG: Once Daily Tacrolimus|DRUG: Twice Daily Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CIMT and taVNS for Hemiplegia in Infants
Status: COMPLETED
Conditions: Infant Development|Hemiplegia|Constraint Induced Movement Therapy
Interventions: DEVICE: transcutaneous auricular vagus nerve stimulation|OTHER: Constraint induced movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: First-In-Human Study of Monoclonal Antibody BMS-986218 by Itself and in Combination With Nivolumab in Participants With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: BMS-986218|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Gait Training Device to Support Body Weight
Status: UNKNOWN
Conditions: Stroke|Brain Injuries, Traumatic|Spinal Cord Injuries|Gait Disorders, Neurologic
Interventions: DEVICE: Lite Run Gait Trainer|DEVICE: Current Harness System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Organ Protection of Astragalus in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: low dose Astragalus|DRUG: high dose astagalus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity of Fluarix™ (Influsplit SSW®) 2007/2008 in People 18 Years Old or Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™/Influsplit SSW® 2007/2008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-Term Efficacy and Safety of Aflibercept Intravitreal Injections for the Treatment of Diabetic Macular Edema
Status: COMPLETED
Conditions: Clinically Significant Diabetic Macular Edema
Interventions: PROCEDURE: Assigned Intervention|DRUG: aflibercept 2.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Injury|Myocarditis|COVID-19 Vaccination|SARS-CoV-2|Cardiac MRI
Interventions: DIAGNOSTIC_TEST: Cardiac PET/MRI|DIAGNOSTIC_TEST: Blood Biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Perilipin, Leptin, Adipolipin, Adiponectin, Resistin, Visfatin, Estrone Levels Pre-post Omentectomy
Status: COMPLETED
Conditions: Gynecologic Cancer
Interventions: OTHER: Preoperative level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Tolerability of Ranibizumab in Mono/Bilateral Wet Age Related Macular Degeneration (w-AMD) Patients in Eyes With BCVA<2/10 and/or 2nd Affected Eye
Status: COMPLETED
Conditions: Wet Age Related Macular Degeneration
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.
Status: NOT_YET_RECRUITING
Conditions: Intraoperative Bleeding
Interventions: DRUG: Intravenous Infusion of propofol, lidocaine, Magnesium sulfate|DRUG: Intravenous infusion of ketamine, lidocaine, Magnesium sulfate|DRUG: Intravenous infusion of dexmedetomidine, lidocaine, Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Technology-Supported Treatment of Sleep Apnea in Prediabetes
Status: RECRUITING
Conditions: Sleep Apnea|PreDiabetes|Overweight or Obesity
Interventions: BEHAVIORAL: Diet and exercise coaching|OTHER: CPAP Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The MIND-GUT Digital Pilot Intervention Study
Status: NOT_YET_RECRUITING
Conditions: Obesity|Depressive Symptoms|Anxiety|Stress|Eating Habit|Dysbiosis
Interventions: BEHAVIORAL: Dietary intervention based on the MIND diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II, Single-arm Study of AZD1775 Monotherapy in Relapsed Small Cell Lung Cancer Patients With MYC Family Amplification or CDKN2A Mutation Combined With TP53 Mutation
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: AZD1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study in Nosocomial Pneumonia Suspected or Confirmed to be Due to Pseudomonas
Status: TERMINATED
Conditions: Pneumonia
Interventions: DRUG: Murepavadin|DRUG: One anti-pseudomonal antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durolane Compared to Saline in Patients With Unilateral Knee Osteoarthritis
Status: COMPLETED
Conditions: Unilateral Knee Osteoarthritis
Interventions: DEVICE: Durolane injection|OTHER: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: everolimus|DRUG: panobinostat|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
Status: COMPLETED
Conditions: Orthostatic Hypotension|Spinal Cord Injuries
Interventions: DRUG: 1.25 mg enalaprilat IV|OTHER: Head up tilt (HUT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Frozen Embryo Transfer (FET) in Natural Cycles or in Natural Cycles Controlled by Human Chorionic Gonadotropin (hCG) Administration
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: HCG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Sphincter Sparing Total Mesorectal Excision for Ultra-low Rectal Cancer After Initial Chemo-radiotherapy (MISS-TRICR).
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: laparoscopic intersphincteric resection (LISR group)|PROCEDURE: Transanal minimally invasive Total mesorectal excision (TAMIS group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Rotavirus Vaccine (Rotavin-M1) Among Healthy Adults
Status: COMPLETED
Conditions: Diarrhea|Vomit|Fever|Nausea|Irritability
Interventions: DRUG: Rotavin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: sugammadex|DRUG: Neostigmine|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 Versus Insulin Lispro (Humalog) on High Blood Sugar in Participants With Type 1 Diabetes Who Use Insulin Pumps
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of a Wireless Patch System (WPS) to Measure Gastrointestinal Motility and Gastric Emptying
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: DIAGNOSTIC_TEST: Scintigraphic gastric emptying scan|DEVICE: Wireless patch system (WPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetic Study of Cabazitaxel in Patients With Advanced Solid Tumors and Liver Impairment
Status: COMPLETED
Conditions: Neoplasm Malignant
Interventions: DRUG: Cabazitaxel (XRP6258)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalised Diet, Exercise and Emotional Support for Lung Cancer Patients Having Chemotherapy, Radiotherapy or Immunotherapy Treatment
Status: RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: Assessment of level of readiness and need for personalised prehabilitation|OTHER: Formation of a personalised prehabilitation plan|OTHER: Daily diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Atorvastatin Versus Rosuvastatin Intensive Statin Regimens on Chinese Elderly Patients Undergoing PCI
Status: UNKNOWN
Conditions: Focus of Study
Interventions: DRUG: Atorvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Placebo|DRUG: Placebo|DRUG: BI 409306|DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MAD Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PB-119 to Subjects With T2DM
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: BIOLOGICAL: PB-119 injection|BIOLOGICAL: PB-119 injection placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Metformin XR|DRUG: Dapagliflozin|DRUG: Placebo matching with Dapagliflozin|DRUG: Placebo matching with Saxagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Armodafinil in Adults With Excessive Sleepiness Associated With Shift Work Disorder
Status: COMPLETED
Conditions: Excessive Sleepiness
Interventions: DRUG: Armodafinil|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial on Vascular Inflammation in Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis|Vascular Inflammation|Coronary Atherosclerosis
Interventions: OTHER: FDG-PET Scan|OTHER: MDCT|OTHER: biopsy and blood collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: batiraxcept|DRUG: Nab paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DUR-928 in Patients With Alcoholic Hepatitis
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: DUR-928 (Moderate AH)|DRUG: DUR-928 (Severe AH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of TG4023 Combined With Flucytosine in Liver Tumors
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: MVA-FCU1, flucytosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dermacyd PH_DESILSTY_FR (Lactic Acid) - Compatibility - Stay on Frutal
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: LACTIC ACID(ND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triclosan Toothpaste as a Preventive Strategy of Mucositis in Smokers
Status: COMPLETED
Conditions: Dental Implants|Cigarette Smoking
Interventions: OTHER: Placebo toothpaste|OTHER: triclosan/copolymer/fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)
Status: COMPLETED
Conditions: Venous Thromboembolism|Bleeding
Interventions: GENETIC: Pharmacogenetic-based warfarin dosing|OTHER: Usual care warfarin dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Surgical Procedures vs Sham Surgery for Patients With Femoroacetabular Impingement and/or Labral Tears.
Status: RECRUITING
Conditions: Surgery
Interventions: PROCEDURE: Arthroscopic surgical procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Zotarolimus-Eluting Stent vs Sirolimus-Eluting Stent for Diabetic Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes
Interventions: DEVICE: Endeavor Resolute stent|DEVICE: Cypher stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study
Status: RECRUITING
Conditions: Septic Shock|Endotoxemia
Interventions: DEVICE: Toraymyxin PMX 20R Extracorporeal Hemoperfusion Cartridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety,Usability and Compliance of Using C-Scan System for Providing Information on Colonic Polypoid Lesions and Masses
Status: COMPLETED
Conditions: Colo-rectal Cancer
Interventions: DEVICE: C-Scan procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Intensity Modulated Radiation Therapy After Surgery in Early Stage of Esophageal Carcinoma;
Status: UNKNOWN
Conditions: Esophageal Neoplasm|Esophageal Cancer TNM Staging Primary Tumor (T) T2|Esophageal Cancer TNM Staging Primary Tumor (T) T3|Esophageal Cancer TNM Staging Regional Lymph Nodes (N) N0|Esophageal Cancer TNM Staging Distal Metastasis (M) M0
Interventions: RADIATION: Prophylactic postoperative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Baclofen Vs Naltrexon in Achieving & Maintaining Abstinence in Alcohol Dependence.
Status: NOT_YET_RECRUITING
Conditions: Alcohol Liver Disease
Interventions: DRUG: Naltrexon|DRUG: Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Implant Treatment and/or Dietary Advice on the Nutrition of Edentulous Ageing Subjects
Status: RECRUITING
Conditions: Edentulous Jaw|Periodontitis
Interventions: PROCEDURE: Implant-supported full-arch fixed dental prostheses（dental intervention,DE）|BEHAVIORAL: Dietary intervention tailored to the dental status (dietary intervention, DI)|PROCEDURE: Delayed implant-supported full-arch fixed dental prostheses（dental intervention,DE）|BEHAVIORAL: Delayed dietary intervention tailored to the dental status (dietary intervention, DI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow up Study of Patients on Fingolimod Who Were Enrolled in the Original Biobank Study (CFTY720DDE01)
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Avocado Honey (Apis Mellifera) on Anthropometric and Biochemical Parameters in Healthy Subjects: A Pilot Study
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DIETARY_SUPPLEMENT: The consumption of avocado honey was analyzed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Juvenile Idiopathic Arthritis (JIA)
Interventions: DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Determine Safety/Efficacy of Lucentis For Treatment Of Retinal Angiomatous Proliferation Secondary To Age Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Lucentis|DRUG: Ranibizumab|DRUG: Ranibizumab (Lucentis)|DRUG: Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of H. Pylori Eradication on Alleviating Symptoms in Functional Dyspepsia Patients
Status: RECRUITING
Conditions: Helicobacter Pylori-positive With Functional Dyspepsia
Interventions: DRUG: K-CAB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Vaccination of Prostate Cancer Patients With Self Dendritic Cells Expressing MUC1
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: DC-Tn-MUC1: autologous dendritic cells expressing Tn-MUC1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of Verapamil in Refractory Epilepsy
Status: UNKNOWN
Conditions: Epilepsy|Seizures
Interventions: DRUG: Verapamil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Adipose Tissue Injections for Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Autologous adipose tissue injection|DRUG: Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study for Yondelis (Trabectedin) in Patients With Advanced Relapsed Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Trabectedin|DRUG: DOXIL|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Phentolamine Mesylate as a Reversing Agent for Local Anesthesia in Children
Status: UNKNOWN
Conditions: Soft Tissue Injuries
Interventions: DRUG: OraVerse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intervention on Socio-emotional Development and Well-being Through ICTs in Early Adulthood
Status: RECRUITING
Conditions: Emotion Regulation
Interventions: BEHAVIORAL: Participation in a socio-emotional competence program through a technological platform (EMOWELL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Feasibility and Preliminary Effects of MR-005 in Persons With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DEVICE: Walking Program with a Music-based, Rhythm-modulating Wearable Sensor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intensive Nutritional Support in Subacute Stroke Patient
Status: COMPLETED
Conditions: Stroke|Rehabilitation|Nutrition
Interventions: DRUG: Omapone Peri 724mL or Winuf Peri 654mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiopathology of Neuromuscular Function Related to Fatigue in Chronic Renal Disease
Status: UNKNOWN
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5|Fatigue
Interventions: OTHER: Handgrip fatigability test|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous Bone Marrow Stem Cells Infusion for the Treatment of Liver Diseases.
Status: UNKNOWN
Conditions: Liver Diseases
Interventions: PROCEDURE: Autologous bone marrow stem cells infusion|DRUG: drugs such as Ursodeoxycholic Acid tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical Trial
Status: RECRUITING
Conditions: Vaginosis, Bacterial
Interventions: DEVICE: Blue Light Emitting Diode (LED) 401 +/- 5nm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Safety Study of BIIB014 in Combination With Levodopa in Moderate to Late Stage Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIIB014|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Registry of Coronary Lithotripsy in Spain.
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Arteriosclerosis|Arterial Occlusive Diseases|Vascular Diseases|Coronary Artery Disease
Interventions: OTHER: Intracoronary lithotripsy (ICL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Two-part Study of the Effects of MK-1029 in Allergen-Challenged Asthmatics (MK-1029-003)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK-1029 10 mg|DRUG: MK-1029 100 mg|DRUG: Placebo for MK-1029 10 mg|DRUG: Placebo for MK-1029 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture is Effective in Cardiac Deconditioning Induced by Head-down Bed Rest
Status: COMPLETED
Conditions: Cardiovascular Abnormalities|Weightlessness
Interventions: DEVICE: electronic acupuncture treatment instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pivotal, Multicenter, Observer-Blind, Randomized Study of Influenza A (H1N1)2009 Monovalent Subunit Vaccine With and Without Adjuvant in Children Ages 6 to <36 Months
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: MF59-eH1N1_f|BIOLOGICAL: MF59-eH1N1_f|BIOLOGICAL: MF59-eH1N1_f|BIOLOGICAL: MF59-eH1N1_f
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective, Observational Study of Wellinks Effect on COPD Hospital Readmissions
Status: RECRUITING
Conditions: COPD|Respiratory Tract Disease|Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive|Lung Diseases
Interventions: OTHER: Wellinks
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies
Status: COMPLETED
Conditions: Soft Tissue Sarcoma|Lymphoma|Leukemia|Wilms' Tumor|Osteosarcoma
Interventions: DRUG: Liposomal Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect and Safety of Low Dose Nebulized Epinephrine in Croup
Status: UNKNOWN
Conditions: Croup|Epinephrine, Administration, Inhalation
Interventions: DRUG: conventional dose epinephrine|DRUG: low dose epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non Inferiority Trial of Locally Manufactured 'Hepa-B' Vaccine in Bangladesh.
Status: COMPLETED
Conditions: Hepatitis B Infection
Interventions: BIOLOGICAL: Hepa-B|BIOLOGICAL: Engerix B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION