pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Assess Absolute Bioavailability (ABA) of TAK-831 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]TAK-831 in Male Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-831 Oral Tablet|DRUG: [14C]TAK-831 IV Infusion|DRUG: [14C]TAK-831 Oral Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Neoadjuvant Chemotherapy Plus Anlotinib in Stage III(N2) Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: Stage III Non-small-cell Lung Cancer
Interventions: DRUG: Anlotinib hydrochloride|DRUG: platinum-based chemotherapy medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilberry (European Blueberries) and Grape Polyphenols on Cognition and Blood Parameters
Status: UNKNOWN
Conditions: Memory|Gene Expression
Interventions: DIETARY_SUPPLEMENT: bilberry (European blueberries) and red grape juice|DIETARY_SUPPLEMENT: placebo juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecularly Targeted Therapy in Treating Patients With BRAF Wild-type Melanoma That is Metastatic
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: OTHER: cytology specimen collection procedure|DRUG: MEK 162 therapy or molecularly targeted therapy|PROCEDURE: therapeutic procedure|OTHER: laboratory biomarker analysis|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness and Safety of a Passive Industrial Exoskeleton for Back Support
Status: COMPLETED
Conditions: Prevention of Diseases of the Musculoskeletal System
Interventions: DEVICE: Passive industrial exoskeleton for back support|OTHER: The protocol will be performed without exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Blood Mangement (PBM) Using IV Iron in Patients With Gynecologic Cancer
Status: NOT_YET_RECRUITING
Conditions: Gynecologic Cancer
Interventions: DRUG: Ferric Carboxymaltose 50Mg/Ml Inj 20Ml|DRUG: RBC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Antibiotic Durations for Gram-negative Bacteremia
Status: COMPLETED
Conditions: Bacteraemia Caused by Gram-Negative Bacteria
Interventions: OTHER: "Fixed long" antibiotic course of 14 days|OTHER: "Fixed short" antibiotic course of 7 days|OTHER: "Individualized duration" of antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers
Status: WITHDRAWN
Conditions: Ebola Hemorrhagic Fever
Interventions: DRUG: AVI-7537|OTHER: Normal Saline Solution (NSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Hemodynamic Optimization of High Risk Patients Undergoing Elective Major Surgical Procedures
Status: WITHDRAWN
Conditions: Hemorrhage
Interventions: OTHER: Augment O2 Delivery by hemodynamic protocol|PROCEDURE: High Risk Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT of PR-ESSENCE - a Problem Solving Model for Youth With Challenging Behavior in Special (SiS) Treatment Homes
Status: RECRUITING
Conditions: Behavior Problems|Neurodevelopmental Disorders
Interventions: BEHAVIORAL: PR-ESSENCE|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimized Duration of Clopidogrel Therapy Following Treatment With the Endeavor - Optimize Trial
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Dose Spinal Bupivacaine for Total Knee Replacement and Recovery Room Wait Time
Status: COMPLETED
Conditions: Spinal Anesthesia|Total Knee Arthroplasty
Interventions: DRUG: Low dose bupivicaine in spinal anesthetic|DRUG: Standard dose bupivacaine in spinal anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Logan Basic Technique Measured by Surface Electromyography (EMG)
Status: COMPLETED
Conditions: Spinal Manipulation
Interventions: PROCEDURE: Logan Basic Technique and Surface EMG|OTHER: Surface EMG|PROCEDURE: Logan Basic Technique Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lyon and Schroth Techniques on Adolescent İdiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: OTHER: Schroth Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Response to Adversity: A Brief Stress Resilience Training
Status: COMPLETED
Conditions: Loneliness|Depression
Interventions: BEHAVIORAL: Mindful response to adversity brief training|BEHAVIORAL: Strengths-based response to adversity brief training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Denosumab With Eldecalcitol or Native Vitamin D in Postmenopausal Women With Osteoporosis.
Status: RECRUITING
Conditions: Osteoporosis in Postmenopausal Women
Interventions: DRUG: Eldecalcitol|DRUG: Native Vitamin D|DRUG: Denosumab|DRUG: Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Effects of M-health App in Obesity Multidisciplinary Outpatient Clinic
Status: UNKNOWN
Conditions: Obesity|m-Health|NAFLD
Interventions: DEVICE: m-Health app|OTHER: conventional outpatient obesity management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Urine Assay to Measure Tenofovir Levels in Patients Taking Tenofovir Alafenamide
Status: COMPLETED
Conditions: Hiv
Interventions: DRUG: FTC/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison of Videolaryngoscope and Direct Laryngoscope in IOP Changes, Throat Pain, IT and Hemodynamic Variables
Status: COMPLETED
Conditions: Intraocular Pressure|Intubation;Difficult
Interventions: PROCEDURE: direct laryngoscope|PROCEDURE: videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nivolumab Monotherapy or Nivolumab Plus Ipilimumab, for Unresectable Malignant Pleural Mesothelioma (MPM) Patients
Status: COMPLETED
Conditions: Mesothelioma
Interventions: DRUG: Nivolumab|DRUG: Nivolumab + Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative|Childhood Myelodysplastic Syndromes|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Disseminated Neuroblastoma|Malignant Neoplasm|Ovarian Choriocarcinoma|Ovarian Embryonal Carcinoma|Ovarian Immature Teratoma|Ovarian Mature Teratoma|Ovarian Mixed Germ Cell Tumor|Ovarian Monodermal and Highly Specialized Teratoma|Ovarian Polyembryoma|Ovarian Yolk Sac Tumor|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Malignant Testicular Germ Cell Tumor|Recurrent Mantle Cell Lymphoma|Recurrent Neuroblastoma|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Refractory Chronic Lymphocytic Leukemia|Refractory Multiple Myeloma|Relapsing Chronic Myelogenous Leukemia|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage II Ovarian Epithelial Cancer|Stage III Malignant Testicular Germ Cell Tumor|Stage III Multiple Myeloma|Stage III Ovarian Epithelial Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Ovarian Epithelial Cancer|Testicular Choriocarcinoma|Testicular Choriocarcinoma and Embryonal Carcinoma|Testicular Choriocarcinoma and Seminoma|Testicular Choriocarcinoma and Teratoma|Testicular Choriocarcinoma and Yolk Sac Tumor|Testicular Embryonal Carcinoma|Testicular Embryonal Carcinoma and Seminoma|Testicular Embryonal Carcinoma and Teratoma|Testicular Embryonal Carcinoma and Teratoma With Seminoma|Testicular Embryonal Carcinoma and Yolk Sac Tumor|Testicular Embryonal Carcinoma and Yolk Sac Tumor With Seminoma|Testicular Teratoma|Testicular Yolk Sac Tumor|Testicular Yolk Sac Tumor and Teratoma|Testicular Yolk Sac Tumor and Teratoma With Seminoma
Interventions: DRUG: ipilimumab|DRUG: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tanezumab and Nerve Function In Arthritis Patients
Status: TERMINATED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: tanezumab|BIOLOGICAL: tanezumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Model-informed Dose De-escalation of Infliximab in Patients With Inflammatory Bowel Diseases
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: DRUG: Infliximab|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACTH for Fatigue in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: ACTH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tipifarnib in Subjects With Chronic Myelomonocytic Leukemia, Other MDS/MPN, and Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myelomonocytic, Chronic
Interventions: DRUG: Tipifarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Evaluation of the Effects of Dexmedetomidine in Diastolic Dysfunction
Status: COMPLETED
Conditions: Under General Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: normal saline(Saline 0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Chloroprocaine 3% - Epidural Anesthesia in Unplanned Caesarean Section
Status: TERMINATED
Conditions: Unplanned Caesarean Section
Interventions: DRUG: Chloroprocaine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexmedetomidine in the Analgesic Prophylaxis , in Patients Undergoing Cardiovascular Surgery
Status: UNKNOWN
Conditions: Cardiopathy|Coronary Artery Disease|Valve Heart Disease|Pain
Interventions: DRUG: Dexmedetomidine|DRUG: 0,9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Clinic Study of 18F-Al-NOTA-PRGD2 in Cancer Diagnostics
Status: UNKNOWN
Conditions: Tumors|Carcinoma, Bronchogenic|Breast Carcinoma|Cancer of Head and Neck|Lymphoma, Malignant|Soft Tissue Neoplasms
Interventions: DRUG: 18F-Al-NOTA-PRGD2 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Water-soluble Ubiquinol Supplementation on Blood Glucose, Lipids, Oxidative Stress, and Inflammation in Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DIETARY_SUPPLEMENT: water-soluble ubiquinol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Medium Chain Fatty Acids on Cognitive Function During Acute Hypoglycemia in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DIETARY_SUPPLEMENT: Medium chain fatty acid (Octanoic and Decanoic acid)|OTHER: Splenda (Placebo Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dasatinib in Adult Patients With Chronic Myeloid Leukemia in China: A Multicenter, Registry Study
Status: COMPLETED
Conditions: Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Interventions: DRUG: Dasatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Changes in Smokers Using on!® Nicotine Pouches
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: OTDN Product 1|OTHER: OTDN Product 2|OTHER: OTDN Product 3|OTHER: No Tobacco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of a Partially Hydrolyzed Formula, Containing Lactobacillus Reuteri, for Infant Colic
Status: UNKNOWN
Conditions: Infant Colics
Interventions: DIETARY_SUPPLEMENT: Milk formula NAN Sensitive, Nestle|DIETARY_SUPPLEMENT: Milk formula Optipro, Nestle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: sarilumab SAR153191 (REGN88)|DRUG: tocilizumab|DRUG: hydroxychloroquine|DRUG: methotrexate|DRUG: sulfasalazine|DRUG: leflunomide|DRUG: subcutaneous placebo|DRUG: intravenous placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS
Status: COMPLETED
Conditions: Nonmalignant Neoplasm|Tuberous Sclerosis|Lymphangioleimyomatosis|Kidney Angiomyolipoma
Interventions: DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Status: RECRUITING
Conditions: Carcinoma, Hepatocellular|Cirrhosis
Interventions: OTHER: Abbreviated Magnetic Resonance Imaging with serum AFP|OTHER: Abdominal Ultrasound Screening with serum AFP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open Label Study of Itacitinib Administered Orally in Patients With Myelofibrosis
Status: COMPLETED
Conditions: MPN (Myeloproliferative Neoplasms)
Interventions: DRUG: itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of a Vaccine Against Essential Hypertension
Status: COMPLETED
Conditions: Mild Essential Hypertension|Moderate Essential Hypertension
Interventions: BIOLOGICAL: CYT006-AngQb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety and Tolerability of Multiple Doses of PF-02545920 in Subjects With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizo-affective Disorder
Interventions: DRUG: PF-02545920
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel, Bevacizumab and Vorinostat for Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Vorinostat, Bevacizumab, Carboplatin, Paclitaxel|DRUG: Vorinostat, Bevacizumab, Carboplatin, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Study #1 of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Ozanimod|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Dronabinol Oral Solution Versus Branded Capsule 5 mg Under Fasting Conditions
Status: COMPLETED
Conditions: Bioavailability
Interventions: DRUG: Dronabinol Capsules, 5 mg|DRUG: Dronabinol Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Transcorneal Electrical Stimulation for the Treatment of Retinitis Pigmentosa - a Safety and Efficacy Multicenter Study
Status: WITHDRAWN
Conditions: Retinitis Pigmentosa
Interventions: DEVICE: Transcorneal Electrical Stimulation using Okustim device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mipolixin® Compared to Poliprotect® in Moderate Functional Dyspepsia and Heartburn.
Status: COMPLETED
Conditions: Dyspepsia|Heartburn
Interventions: DEVICE: Mipolixin®|DEVICE: Poliprotect®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neonatal Resuscitation With Supraglottic Airway Trial
Status: UNKNOWN
Conditions: Asphyxia Neonatorum
Interventions: DEVICE: Supraglottic airway|DEVICE: Face-mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticotropin Releasing Hormone (CRH) Responsiveness in Children With Functional Dyspepsia
Status: WITHDRAWN
Conditions: Functional Dyspepsia
Interventions: DRUG: Acthrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Efficacy of the Consumption of a Heat-treated Lactobacillus Paracasei (GM080) on Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: GM080|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
Status: COMPLETED
Conditions: Ureteral Injury
Interventions: DRUG: Pyridium|DRUG: Riboflavin|DRUG: Thiamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nurse-led Reminder Program for Therapy Adherence, Clinical Outcomes and Trust in Nurses in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: BEHAVIORAL: Nurse-led reminder program through email
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Femtosecond Laser System as Compared to Continuous Curvilinear Capsulorhexis for Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: FS Laser Surgery|PROCEDURE: CCC Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Versus Minimal Surveillance of Patients With Resected Dukes B2-C Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Cancer|Surveillance
Interventions: OTHER: surveillance program after completion of primary treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Post-Operative Enteral Feeding in Patients With Advanced Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DIETARY_SUPPLEMENT: Early post-operative enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic
Status: COMPLETED
Conditions: Athlete|Sedentary Behavior
Interventions: DIETARY_SUPPLEMENT: Synbiotic complement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telerehabilitation-based Motor Imagery in Nonspecific Low Back Pain
Status: RECRUITING
Conditions: Motor Imagery
Interventions: BEHAVIORAL: Telerehabilitation-based motor imagery training|BEHAVIORAL: Stabilization exercises group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Intracerebral Hemorrhage
Interventions: DRUG: Apixaban Oral Tablet|DRUG: Dabigatran|DRUG: Edoxaban Tablets|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Outcome Measure at Stryker Spine
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease|Degenerative Scoliosis
Interventions: DEVICE: Spinal Fusion|DEVICE: Spinal Fusion|DEVICE: Spinal Deformities Correction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deciphering Preserved Autonomic Function After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Autonomic Imbalance|Autonomic Dysreflexia|Orthostatic Hypotension
Interventions: DIAGNOSTIC_TEST: Tests of sympathetic inhibition|DIAGNOSTIC_TEST: Tests of sympathetic activation|DIAGNOSTIC_TEST: Testing of autonomic dysreflexia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Sulfatinib on Relapsed or Refractory Drug Resistant Osteosarcoma
Status: NOT_YET_RECRUITING
Conditions: Osteosarcoma
Interventions: DRUG: Sulfatinib|DRUG: Etoposide|DRUG: Isophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological and Psychosocial Intervention With War-Affected Children
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depression|Anxiety|Conduct|Pro-social Behavior
Interventions: BEHAVIORAL: Trauma Focused Cognitive Behavioral Therapy|BEHAVIORAL: Child Friendly Space
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism
Status: TERMINATED
Conditions: Autism|Pervasive Developmental Disorder
Interventions: DRUG: oral zinc and vitamin C supplements|OTHER: oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco
Status: RECRUITING
Conditions: Smoking Cessation|Marijuana Use
Interventions: BEHAVIORAL: Behavioral: Quitline treatment as usual|BEHAVIORAL: QL Marijuana Check-Up intervention (QL-MJCU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus
Status: UNKNOWN
Conditions: High Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR Kit
Interventions: DEVICE: performance evaluation study of RealDetect RT-PCR Kit for COVID-19 detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pioglitazone to Treat Fatty Liver in People With HIV Infection
Status: COMPLETED
Conditions: HIV Infections|Hepatic Steatosis|Insulin Resistance
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre Procedural Biomarkers Might Predict Recurrent Atrial Fibrillation After Catheter Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DIAGNOSTIC_TEST: Measuring Serum bio-markers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: IV Iron Sucrose vs Oral FeSO4 in Treating IDA in Pediatric IBD
Status: WITHDRAWN
Conditions: Iron Deficiency Anemia|Inflammatory Bowel Disease
Interventions: DRUG: Intravenous iron sucrose|DRUG: Oral ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pictorial Warning Labels, Numeracy, and Memory for Numeric Cigarette Health-risk Information Over Time
Status: COMPLETED
Conditions: Smoking, Cigarette|Smoking Cessation
Interventions: BEHAVIORAL: text-only PWL|BEHAVIORAL: low-emot PWL|BEHAVIORAL: high-emot PWL|BEHAVIORAL: immed posttest|BEHAVIORAL: delay posttest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Y Zevalin and BEAM in Autologous Stem Cell Transplantation (ASCT) for Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Y Zevalin|DRUG: In Zevalin|DRUG: Rituxan|DRUG: BCNU|DRUG: VP -16|DRUG: Ara-C|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Power Ball on Proximal Muscle and Refractive Errors in Developmental Delay.
Status: RECRUITING
Conditions: Developmental Delay
Interventions: OTHER: conventional therapy|OTHER: conventional therapy along with standard therapy and stability exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction II
Status: RECRUITING
Conditions: Bacterial Keratitis
Interventions: DRUG: Difluprednate Ophthalmic|DRUG: Rose Bengal|DRUG: Moxifloxacin Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyloid Cardiomyopathy, Transthyretin-Related
Interventions: DRUG: 99mTc-PYP or 99m Tc-HDP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Progesterone Augmentation of Nicotine Replacement Therapy Study
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Progesterone (200 mgs BID)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Famciclovir Single 1500 mg Dose in Adolescents With Recurrent Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DRUG: Famciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Meibomian Gland Related Therapy on the Morphology of Meibomian Gland
Status: WITHDRAWN
Conditions: Xerophthalmia
Interventions: DEVICE: Intense pulsed light therapy|OTHER: Hot compress massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of PNF and Electrical Muscle Stimulation on Spasticity and Hand Function in Stroke Patients.
Status: COMPLETED
Conditions: Stroke|Proprioceptive Disorders|Balance; Distorted
Interventions: OTHER: experimental group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy, Safety, and Tolerability of Met DR in Subjects With T2DM Over 12 Weeks
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Met DR|DRUG: Met XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SI-B003, a PD-1/CTLA-4 Bispecific Antibody, in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: SI-B003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Capecitabine Plus Aflibercept to Treat Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Capecitabine and aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paracetamol Plus Tramadol Versus Fentanyl As Preemptive Analgesia For Enhanced Recovery After Day Case Surgeries
Status: ENROLLING_BY_INVITATION
Conditions: Preemptive Paracetamol Plus Tramadol and Preemptive Fentanyl
Interventions: DRUG: tramadol plus paracetamol|DRUG: Fentanyl|DRUG: propofol and muscle relaxant (cisatracurium)|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pausing Antiretroviral Treatment Under Structured Evaluation
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: 3BNC117-LS-J|DRUG: 10-1074-LS-J|DRUG: Placebo for 3BNC117-LS-J|DRUG: Placebo for 10-1074-LS-J
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery
Status: COMPLETED
Conditions: Pediatric Cardiac Surgery|Complication of Extracorporeal Circulation
Interventions: DRUG: Tranexamic acid|DRUG: Epsilon Aminocaproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
Status: NOT_YET_RECRUITING
Conditions: Endophthalmitis
Interventions: DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effect of Vaseline and Bepanthen® "Wund- Und Heilsalbe" on the Wound Healing Following Laser Therapy
Status: COMPLETED
Conditions: Photodamaged Skin
Interventions: DEVICE: CO2-laser|DRUG: Vaseline|DRUG: Bepanthen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adaptation of the PCIP for Children Aged 6 to 11
Status: SUSPENDED
Conditions: Post-Traumatic Stress Disorder in Children|Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: Primary Care Intervention for PTSD (PCIP) Youth aged 6 -11|BEHAVIORAL: Waitlist Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Prospective, Multicenter Study to Compare Enteral Nutrition to Parenteral Nutrition as Feeding Support in Patients Presenting Malignant Hemopathy Who Underwent an Allogeneic Hematopoietic Stem Cell Transplantation.
Status: UNKNOWN
Conditions: Myeloablative Allo-SCT
Interventions: DRUG: Enteral nutrition alanyl-glutamin, Dipeptiven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Clinical Trial of PepCan in Head and Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: PepCan|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photoacoustic Computed Tomography for Pre-Operative Reconstructive Flap Angiography
Status: WITHDRAWN
Conditions: Other Reconstructive Surgery|Plastic Surgery
Interventions: DIAGNOSTIC_TEST: Photoacoustic Computed Tomography (PACT) Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Mesenchymal Stem Cells in the Treatment of Relapsed/Refractory Severe Acquired Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: BIOLOGICAL: Intravenous bone marrow mesenchymal stem cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Carboplatin, 5-FU and Cetuximab in Elderly Fit (no Frailty) Patients With Recurrent/Metastatic HNSCC
Status: COMPLETED
Conditions: Metastatic or Recurrent Head and Neck Squamous Cell Cancer
Interventions: DRUG: Carbo, 5FU, Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic, Safety, Tolerability, and Immunogenicity Study of SB8 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: SB8|BIOLOGICAL: EU sourced Avastin®|BIOLOGICAL: US Sourced Avastin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the Xoft® Axxent® Electronic Brachytherapy System for the Treatment of Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DEVICE: Treatment with Electronic Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study After 11 Years of Patients Who Were Included in the BENEFIT Trial (304747) With a First Demyelinating Event Suggestive of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Several diagnostic procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Capmatinib Efficacy in Comparison With Docetaxel in Previously Treated Participants With Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Capmatinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin
Status: COMPLETED
Conditions: Pharmacokinetics|Healthy Volunteers
Interventions: DRUG: Rosuvastatin|DRUG: Nirmatrelvir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Digital Tool Enhancing GPs' Information Management for Patients With Multimorbidity - a Pilot Study
Status: RECRUITING
Conditions: Asthma|Breast Neoplasms|Coronary Disease|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Pulmonary Disease, Chronic Obstructive|Comorbidities and Coexisting Conditions
Interventions: OTHER: gp-multitool.de
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis
Status: UNKNOWN
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Atorvastatin|DRUG: L-Carnitine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the VividTrac® Videolaryngoscope to Direct Laryngoscopy in Adults Under Manual Inline Stabilization
Status: WITHDRAWN
Conditions: Endotracheal Intubation
Interventions: DEVICE: laryngoscopy|PROCEDURE: Manual Inline Stabilization|DEVICE: VividTrac®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Study of Eribulin Followed by AC as Preoperative Therapy for HER2-negative Inflammatory Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Breast Cancer|Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
Interventions: DRUG: Eribulin|DRUG: Adriamycin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Methylated Vitamin B Complex on Depression
Status: COMPLETED
Conditions: Depression
Interventions: DIETARY_SUPPLEMENT: Max Stress B|DIETARY_SUPPLEMENT: Placebo Max Stress B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine and Ovarian Reserve
Status: COMPLETED
Conditions: Fertility Issues|Vaccine Adverse Reaction
Interventions: BIOLOGICAL: SARS-CoV-2 virus vaccines|DIAGNOSTIC_TEST: AMH sampling|DIAGNOSTIC_TEST: anti Covid-19 antibody levels (Serology)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
Status: NOT_YET_RECRUITING
Conditions: Chronic Liver Disease and Cirrhosis|Liver Cancer|Non-Alcoholic Fatty Liver Disease|Non-Alcoholic Steatohepatitis|Viral Hepatitis B|Viral Hepatitis C|Viral Hepatitis D
Interventions: PROCEDURE: Blood sample during surgery|PROCEDURE: Taking an additional biopsy|DIAGNOSTIC_TEST: Blood sample during diagnostic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of TBC1D4 in Exercise- and Insulin-induced Glucose Metabolism in Human Skeletal Muscle
Status: COMPLETED
Conditions: Exercise|Insulin Sensitivity|Skeletal Muscle
Interventions: OTHER: Acute exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of MCT Oil for Enhancement of Weight Loss in Obese Patients
Status: COMPLETED
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: 1170-1870 kcal/day liquid diet|PROCEDURE: Gastric bypass surgery|PROCEDURE: Biopsy.visceral adipose tissue|PROCEDURE: Biopsy.omental adipose tissue|PROCEDURE: Biopsy. subcutaneous abdominal adipose tissue|PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Effect of Sanyinjiao (SP6) Acupressure on Early Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DEVICE: acupressure by ankle band
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Based Chemotherapy Plus or Minus Induction Chemotherapy to Decrease Events in Head and Neck Cancer (DeCIDE)
Status: COMPLETED
Conditions: Cancer of the Pharynx|Cancer of the Larynx|Cancer of the Nasal Cavity|Paranasal Sinus Neoplasms|Cancer of the Oral Cavity
Interventions: DRUG: docetaxel|DRUG: cisplatin|DRUG: hydroxyurea|DRUG: fluorouracil|PROCEDURE: chemotherapy|PROCEDURE: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Denagliptin In Subjects With Type 2 Diabetes Mellitus (T2DM)
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: denagliptin (GW823093)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Dynamic F-DOPA PET for Differential Diagnosis Between Recurrence and Radionecrosis of Brain Metastasis
Status: RECRUITING
Conditions: Brain Metastases|Radiation Necrosis
Interventions: OTHER: early 18F-FDOPA uptake
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuroscience-informed Treatment to Remotely Target Reward Mechanisms in Post-acute Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa
Interventions: BEHAVIORAL: Positive Affect Treatment for Anorexia Nervosa (PAT-AN):|BEHAVIORAL: Psychoeducational and Behavioral Therapy (PBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Performance and Safety of Expedial and Compare it to Expanded Polytetrafluoroethylene (ePTFE) Vascular Access Grafts
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Expedial Vascular Access Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Local/ MAC Anesthesia in Lumbar Decompression
Status: RECRUITING
Conditions: Lumbar Spinal Stenosis
Interventions: DRUG: Propofol Injection|DRUG: Lidocaine Hydrochloride, Injectable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vulnerability of Carotid Artery Plaques and Prediction of Cardio-Cerebrovascular Event Risk Using Ultrasonic Imaging
Status: NOT_YET_RECRUITING
Conditions: Carotid Plaque|Ischemic Stroke|Cardiovascular Events
Interventions: OTHER: Cardiovascular and cerebrovascular diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p