pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Gut Hormone LEAP2 in Metabolism and Eating Behaviour: Fixed Meal Testing
Status: RECRUITING
Conditions: Eating Behavior|Obesity|Appetitive Behavior
Interventions: DIETARY_SUPPLEMENT: 0 kcal liquid meal|DIETARY_SUPPLEMENT: 600 kcal liquid meal|DIETARY_SUPPLEMENT: 900 kcal liquid meal (only for group without obesity)|DIETARY_SUPPLEMENT: 1200 kcal liquid meal|DIETARY_SUPPLEMENT: 1800 kcal liquid meal (only for group with obesity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of PF-06480605 in Adult Participants With Moderate to Severe Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn Disease
Interventions: DRUG: Investigational Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implication of Metabolic and Genomic Modifications in Elderly Subjects
Status: COMPLETED
Conditions: Insulin Sensitivity|Aging
Interventions: DRUG: euglycemic hyperinsulinemic clamp|PROCEDURE: muscle biopsy|DEVICE: indirect calorimetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Comparing Ultrasound-guided FICNB Block to Systemic Analgesia in Treatment of Pediatric Femur Fracture
Status: COMPLETED
Conditions: Femur Fracture
Interventions: PROCEDURE: Ultrasound-Guided Fascia Iliaca Compartment Nerve Block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Collagenase and Needle Aponeurotomy: Single Modality Versus Combination Treatment for Dupuytren's Disease
Status: WITHDRAWN
Conditions: Dupuytren Contracture
Interventions: DRUG: Collegenase injection|PROCEDURE: Needle aponeurotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Epidural Block on the Prognosis in Patients With Pancreatic Cancer Undergoing Distal Pancreatectomy
Status: UNKNOWN
Conditions: Cancer of Pancreas
Interventions: OTHER: GEA|OTHER: PCEA|OTHER: GA|OTHER: PCIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Cultivating Self-compassion Improve Resilience to Criticism and Improve Mental Health in Adults With ADHD?
Status: UNKNOWN
Conditions: ADHD|Depression|Stress|Self-Criticism|Anxiety|Wellbeing|Self-compassion
Interventions: BEHAVIORAL: Online self-compassion intervention|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Effects of Inspiratory Muscle Training in Cerebral Palsy
Status: COMPLETED
Conditions: Aging|Cerebral Palsy|Muscle Weakness|Older People--Abuse of|Physical Inactivity|Respiratory Tract Problem
Interventions: DEVICE: INSPIRATORY MUSCLE TRAINING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin Therapy in Smith-Lemli-Opitz Syndrome
Status: COMPLETED
Conditions: Smith-Lemli-Opitz Syndrome
Interventions: DRUG: Simvastatin Susp.|DRUG: OraPlus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Surufatinib Combined With Chemotherapy as Neoadjuvant Treatment in Osteosarcoma
Status: RECRUITING
Conditions: Osteosarcoma
Interventions: DRUG: Surufatinib plus chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Collagen Efficacy on Skin Anti-aging in 30 to 50-Year-Old Women
Status: COMPLETED
Conditions: Skin Laxity|Skin Fold
Interventions: DIETARY_SUPPLEMENT: WonderLab Collagen Tripeptide Drink|DIETARY_SUPPLEMENT: Ordinary Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fucoidan Improves the Metabolic Profiles of Patients With Non-alcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: OTHER: 275mg Oligo Fucoidan + 275mg HS Fucoxanthin|OTHER: placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Regisry of the Stroke Patients in Assiut University Hospital
Status: UNKNOWN
Conditions: All Patients With Ischemic Cerebrovascular Stroke Aged ≥18 Years of Both Sex
Interventions: DRUG: tissue plasminogen activator|PROCEDURE: thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HAIC Plus Targeted Therapy and/or PD-1 Inhibitors for Unresectable Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin, fluorouracil, and leucovorin (FOLFOX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale
Status: RECRUITING
Conditions: Lung Cancer|Lung Neoplasms/Diagnosis
Interventions: BEHAVIORAL: MyLungHealth|BEHAVIORAL: DecisionPrecision+
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Patient Oriented Discharge Summary Impact Study
Status: TERMINATED
Conditions: Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Pneumonia|Hip Fracture|Total Hip Replacement|Total Knee Replacement
Interventions: OTHER: Patient Oriented Discharge Summary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neratinib + Valproate in Advanced Solid Tumors, w/Expansion Cohort in Ras-Mutated Ca
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: Neratinib|DRUG: Divalproex Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Identification of Cardiac Involvement in Patients With Carcinoid: Clinical and Prognostic Implications
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: OTHER: Evaluation of blood levels of biomarkers of cardiac damage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective Study Evaluating Seroprevalence and Seroconversion of Antibodies Against Adeno-associated Virus (AAV)
Status: TERMINATED
Conditions: Hemophilia A
Interventions: PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Development of a Novel Method to Study in Vivo Fatty Acid Metabolism Using Stable Isotope Labeled Fatty Acids in Humans
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: OTHER: Oleic Diet|OTHER: Palmitic Diet|OTHER: Stearic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia
Status: UNKNOWN
Conditions: Myopia
Interventions: PROCEDURE: Corneal lenticule extraction for advanced refractive correction (CLEAR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pulsating ElectroMagnetive Treatment (PEMF) at Treatment Resistant Depression
Status: COMPLETED
Conditions: Treatment Resistant Depression
Interventions: DEVICE: Re5 Pulsating ElectroMagnetic Fields|DEVICE: Re5 Pulsating ElectroMagnetic Fields (PEMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraprostatic Botulinum Toxin Type "A" Injection in Patients With Benign Prostatic Hyperplasia and Unsatisfactory Response to Medical Therapy
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)|Benign Prostatic Enlargement (BPE)
Interventions: DRUG: BOTOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001)
Status: TERMINATED
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: MK-2118 (IT)|DRUG: MK-2118 (SC)|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INAVAC Vaccine Phase III (Immunobridging Study) in Healthy Population Aged 12 to 17 Years Old
Status: RECRUITING
Conditions: COVID-19 Pandemic|COVID-19 Vaccines
Interventions: BIOLOGICAL: INAVAC (Vaksin Merah Putih - UA-SARS CoV-2 (Vero Cell Inactivated) 5 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of the Effects of DHA in the Treatment of Seizure Disorders
Status: TERMINATED
Conditions: Epilepsy (Treatment Refractory)
Interventions: DIETARY_SUPPLEMENT: Fish Oil|OTHER: Safflower Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Pelvic Muscle Training and Pilates Exercises for UI in Postmenopausal Women
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: PFMT|OTHER: PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Human Mesenchymal Stem Cells for Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Dementia
Interventions: DRUG: Human Mesenchymal Stem Cells and Lactated Riunger's Solution|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sensation of Dyspnea and Experience of Patients With Heart Failure
Status: RECRUITING
Conditions: Decompensated Heart Failure
Interventions: DEVICE: Immersive Virtual Reality glasses|OTHER: early mobilization protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Monotherapy With Endocrine Therapy or Accelerated Partial Breast Irradiation Following Lumpectomy for Low Risk Breast Cancer Patients Over 65 (CAMERAN)
Status: RECRUITING
Conditions: Breast Cancer|Quality of Life
Interventions: RADIATION: Accelerated Partial Breast Irradiation (APBI)|DRUG: tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy, Pharmacokinetics, Pharmacodynamics and Safety of CT-P53 and Ocrevus in Patients With Relapsing-remitting Multiple Sclerosis
Status: RECRUITING
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: BIOLOGICAL: CT-P53|BIOLOGICAL: US-Ocrevus|BIOLOGICAL: EU-Ocrevus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self Assessment of Fetal Ultrasound Images
Status: UNKNOWN
Conditions: Impact of Self Assessment of Foetal Ultrasound Images on Image Quality
Interventions: BEHAVIORAL: Self assessment of ultrasound fetal biometry images|BEHAVIORAL: assessment of ultrasound fetal biometry images by expert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Anodal and Cathodal Transcranial Direct Current Stimulation in Stroke Recovery
Status: UNKNOWN
Conditions: Stroke
Interventions: PROCEDURE: transcranial direct current stimulation (Anodal)|PROCEDURE: transcranial direct current stimulation (Cathodal)|PROCEDURE: transcranial direct current stimulation (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into the Effect of Dapagliflozin on Ketogenesis in Type 1 Diabetes
Status: COMPLETED
Conditions: Evaluate Ketogenic Stress
Interventions: DRUG: Exenatide/Exenatide extended release|DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study of TD-9855 to Treat Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: TD-9855 Group 1|DRUG: TD-9855 Group 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GHSG-AFM13 An Open-label, Multicenter Phase II Trial With AFM13 in Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: AFM13
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity and Specificity of Color Doppler Directed Temporal Artery Biopsy as Compared to Standard Random Biopsy in the Diagnosis of Temporal Arteritis
Status: UNKNOWN
Conditions: Temporal Arteritis|Duplex of Temporal Artery|Biopsy of Temporal Artery
Interventions: PROCEDURE: biopsy of temporal artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Patent Foramen Ovale and the Risk of Postoperative Delirium Following Elective Hip and Knee Arthroplasty Surgeries
Status: COMPLETED
Conditions: Foramen Ovale, Patent|Delirium|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: OTHER: TTE Bubble Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Safety and Efficacy of Meplazumab for Injection Patients COVID-19
Status: WITHDRAWN
Conditions: COVID-19
Interventions: BIOLOGICAL: Meplazumab foe injection|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Dissolution of Cholesterol Gallstones Using Oral Aramchol - A Proof of Concept Phase IIa Study
Status: TERMINATED
Conditions: Gallstones
Interventions: DRUG: Aramchol|DRUG: Placebo|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Nosocomial Bacteremia Among Zambian Neonates
Status: COMPLETED
Conditions: Neonatal Sepsis|Neonatal Mortality
Interventions: DRUG: Chlorhexidine gluconate (CHG)|BEHAVIORAL: Hand hygiene (HH)|BEHAVIORAL: Infection control training|OTHER: Infection control reminders via SMS text
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Probiotic VSL#3 on Expression of Small Intestinal Renin-angiotensin System
Status: COMPLETED
Conditions: the Local Renin-angiotensin System (RAS) in Small Intestinal Mucosa in Man
Interventions: BIOLOGICAL: VSL#3|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Combined Prasugrel and Bivalirudin Versus Clopidogrel and Heparin in Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Prasugrel|DRUG: Bivalirudin|DRUG: Clopidogrel|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center)
Status: COMPLETED
Conditions: Depression|Acute Pain|Chronic Pain
Interventions: OTHER: Pharmacogenetic testing|OTHER: Clinical decisions support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community
Status: ENROLLING_BY_INVITATION
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: C-Raven Virtual Tobacco Cessation Counseling|DRUG: Nicotine Replacement Product|OTHER: Community Health Worker|OTHER: Lung Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate, Prednisone, and Apalutamide in Treating Patients With Hormone-Naive Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Prostate Carcinoma Metastatic in the Bone|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Abiraterone Acetate|DRUG: Apalutamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Efficacy and Safety of Botulinum Toxin A (Botox-Allergan Inc) in Migraine Headaches
Status: COMPLETED
Conditions: Refractory Migraine
Interventions: DRUG: Botox|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Implementation of a Telemedicine Program on Patients Diagnosed With Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma|Telemedicine|Adherence, Treatment|Quality of Life|Control
Interventions: DEVICE: The mobile application ESTOI for Asthmatic patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AN2728 Topical Ointment, 2% in Children, Adolescents, and Adults (Aged 2 Years and Older) With Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: AN2728 Topical Ointment, 2%|DRUG: Matching vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Positron Emission Tomography (PET) Study to Determine the Effect of TAK-041 on Amphetamine-Induced Dopamine Release in the Central Nervous System (CNS)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Amphetamine|DRUG: TAK -041|DRUG: [11C] (+)-4-propyl-(+)-4-propyl-9-hydroxynaphthoxazine (PHNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Crossover Trial of Bright Light Therapy in Crohn's Disease on Intestinal Barrier Homeostasis
Status: RECRUITING
Conditions: Inflammatory Bowel Disease
Interventions: DEVICE: Bright Light Therapy|DEVICE: Placebo Retimer Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanded PK and PD of Insulin Glulisine Versus Insulin Aspart in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: insulin glulisine, insulin aspart|DRUG: insulin aspart, insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Centrifugation vs. Multiple-pass Hemofiltration of the Residual Cardiopulmonary Bypass Volume
Status: COMPLETED
Conditions: Coronary Artery Disease|Heart Valve Diseases
Interventions: PROCEDURE: Centrifugation|PROCEDURE: Multiple-pass hemofiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Systane Ultra|OTHER: Bausch and Lomb Sensitive Eyes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Outcome and Analgesia in TKA: Radiofrequency vs Continuous Adductor Canal Block
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Pulsed and Continuous Radiofrequency|DRUG: Continuous Adductor Canal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study, Betaseron Versus Copaxone for Relapsing Remitting or CIS Forms of MS Using Triple Dose Gad 3 T MRI
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Betaseron|DRUG: Copaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Extension Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B
Status: COMPLETED
Conditions: Hemophilia B
Interventions: BIOLOGICAL: rIX-FP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Inpatient Stoma-Nurse Teaching Versus Stoma Teaching Video Combined With Inpatient Stoma-Nurse Teaching
Status: UNKNOWN
Conditions: Ileostomy - Stoma|Colostomy Stoma
Interventions: OTHER: Ostomy Education Video|OTHER: Control - Standard ostomy education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Self-directed Adapted Gaming Exercises for Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident
Interventions: BEHAVIORAL: Repetitive, task-specific upper limb practice|OTHER: Conventional care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TIMBER Psychotherapy and Ketamine Single Infusion in Chronic PTSD
Status: UNKNOWN
Conditions: PTSD
Interventions: DRUG: Ketamine|BEHAVIORAL: TIMBER Psychotherapy|DRUG: Placebo (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetazolamide on REM OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Placebo oral capsule|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral and Nasal Feeding on Cerebral Small Vessel Disease
Status: RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: DEVICE: Nasogastric Tube Feeding|DEVICE: Intermittent Oro-esophageal Tube Feeding|BEHAVIORAL: comprehensive rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Effectiveness of EVICEL as an Adjunct to Sutured Dural Repair
Status: COMPLETED
Conditions: Dura Defects
Interventions: BIOLOGICAL: Evicel|OTHER: Sutures only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Effect of GM-CSF on Macrophages in Ependymoma
Status: COMPLETED
Conditions: Ependymoma, Recurrent Childhood|Ependymoma
Interventions: DRUG: Granulocyte Macrophage Colony Stimulation Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antioxidant Supplementation in Trauma Patients
Status: TERMINATED
Conditions: Multiple Trauma
Interventions: DIETARY_SUPPLEMENT: powdered antioxidant|DIETARY_SUPPLEMENT: powdered cornstarch placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: MDR-JuggerKnot Mini Soft Anchor in Maxillofacial TMJ
Status: WITHDRAWN
Conditions: TMJ Disc Disorder|TMJ Pain|TMJ Sounds on Opening/Closing the Jaw|TMJ Disease
Interventions: DEVICE: JuggerKnot Mini Soft Anchor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Oral Carbohydrate Administration on Postoperative Well-being
Status: COMPLETED
Conditions: Colorectal Cancer|Glucometabolic Response|Subjective Goodness|Life Quality
Interventions: DIETARY_SUPPLEMENT: Carbonhydrate rich drink|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-Müllerian Hormone (AMH) Measured With Fully Automated Assay Versus AFC in the Prediction of Ovarian Response
Status: COMPLETED
Conditions: Ovarian Response
Interventions: DRUG: 150 IU of HMG in patients with age ≤ 35 years|DRUG: 225 IU of HMG in patients with age > 35 years
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Decitabine + BUCY vs BUCY Conditioning Regimen for TP53+ Myeloid Tumors Undergoing Allo-HSCT
Status: UNKNOWN
Conditions: TP53|Myeloid Tumors|Conditioning|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Decitabine|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen for the Treatment of Unfavorable Bleeding in Contraceptive Implant Users
Status: COMPLETED
Conditions: Menstruation Disturbances
Interventions: DRUG: Tamoxifen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prognostic Factors for Treatment Responses in Patients With Active Lupus Nephritis at Sohag University Hospital
Status: UNKNOWN
Conditions: We Aim to Examine the Predictors of Sustained Complete Renal Remission in Patients With Lupus Nephritis at Sohag University Hospital
Interventions: DRUG: sandimmun
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Green Tea Mouthwash on Generalized Plaque- Induced Gingivitis
Status: COMPLETED
Conditions: Plaque Induced Gingivitis
Interventions: OTHER: green tea mouthwash|OTHER: green tea mouthwash|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluids Affecting Bladder Urgency and Lower Urinary Symptoms
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Urgency|Urinary Bladder, Overactive|Urinary Incontinence, Urge|Caffeine|Alcohol Drinking|Lower Urinary Tract Symptoms
Interventions: BEHAVIORAL: Reducing Potentially Irritating Beverages|BEHAVIORAL: Adopting the USDA Healthy Eating Habits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Optical Coherence Tomography-derived Minimal Lumen Area, Invasive Fractional Flow Reserve and FFRCT
Status: RECRUITING
Conditions: Coronary Stenosis
Interventions: DIAGNOSTIC_TEST: OCT, FFR, CTA and FFRCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Impact of Clacoterone 1% Cream on Skin Barrier Properties in Acne Prone Patients
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Winlevi (clascoterone) 1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science
Status: UNKNOWN
Conditions: Malignant Tumor of Small Intestine Metastatic to Liver
Interventions: DRUG: Bushen-Jianpi Dedoction|DRUG: cinobufotalin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Validation of Advanced Colorectal Neoplasm Risk Categories in a Prospective Cohort in Mexico
Status: RECRUITING
Conditions: Colorectal Cancer Screening
Interventions: DIAGNOSTIC_TEST: Fecal inmunochemical test|DIAGNOSTIC_TEST: Colonoscopy|BIOLOGICAL: Optional collection of tissue, blood and urine for future biomedical research
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of SLN Block for Chronic Cough
Status: COMPLETED
Conditions: Cough|Superior Laryngeal Nerve Block|Neurogenic Cough
Interventions: PROCEDURE: Superior laryngeal nerve block|PROCEDURE: Injection of placebo (saline)|PROCEDURE: Injection of steroid-lidocaine mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability and Food-Effect Study of the Fixed Dose Combination of GSK3640254 and Dolutegravir (DTG) in Healthy Participants
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: DTG|DRUG: GSK3640254/DTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: Macitentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mushroom Blend on Oxygen Kinetics
Status: COMPLETED
Conditions: Oxygen Utilization|Oxygen Kinetics
Interventions: DIETARY_SUPPLEMENT: Mushroom Blend|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Percutaneous Posterior Tibial Nerve Stimulation in Post-operative Voiding Dysfunction After Deep Endometriosis Surgery
Status: COMPLETED
Conditions: Endometriosis|Dysuria
Interventions: PROCEDURE: Self-catheterization only|DEVICE: Posterior tibial nerve stimulation + self-catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom-driven Referral for Evaluation of Chronic Thromboembolic Disease or Pulmonary Hypertension in Patients With Previous Acute Pulmonary Embolism
Status: UNKNOWN
Conditions: Chronic Thromboembolic Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: CTEPH/CTED work-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H3733 Liquid Oral Dosage Form|DRUG: ABI-H3733 Solid Oral Dosage Form|DRUG: Placebo to ABI-H3733 Liquid Oral Dosage Form|DRUG: Placebo to ABI-H3733 Solid Oral Dosage Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creative Practice as Mutual Recovery
Status: COMPLETED
Conditions: Individuals Experiencing Mild or Moderate Mental Health Issues
Interventions: OTHER: Group drumming (participatory)|OTHER: Group drumming (live)|OTHER: Group drumming (recorded)|OTHER: Comparative activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT
Status: COMPLETED
Conditions: AML|ALL|Undifferentiated Leukemia|Biphenotypic Leukemia|Refractory Anemia|Refractory Anemia With Ringed Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Ref. Cytopenia w Multilineage Dysplasia & Ringed Sideroblasts|Refractory Anemia With Excess Blasts-1 (5-10% Blasts)|Refractory Anemia With Excess Blasts-2 (10-20% Blasts)|Myelodysplastic Syndrome, Unclassified|MDS Associated With Isolated Del (5q)
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Effectiveness of Hairfinity on Improving Hair Health and Rate of Growth
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DIETARY_SUPPLEMENT: Hairfinity #1|DIETARY_SUPPLEMENT: Hairfinity #2|DIETARY_SUPPLEMENT: Hairfinity #3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Birth Ball Versus Meperidine and Haloperidol Injection for Pain Relief During First Stage of Labour
Status: UNKNOWN
Conditions: Parturition|Humanizing Deliver|Labor Pain|Natural Childbirth|Labor Onset|First Labor Stage
Interventions: DRUG: pethidine and haloperidol injection|OTHER: birth ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Percutaneous Needle Electrolysis (PNE) on Tendinopathy
Status: RECRUITING
Conditions: Posterior Tibial Tendon Dysfunction
Interventions: OTHER: Percutaneous needle electrolysis|OTHER: Therapeutic exercise|OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide phosphate|DRUG: ifosfamide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography (PET) Imaging of Glial Activation in Psychotic Disease States
Status: TERMINATED
Conditions: Schizophrenia|Bipolar Disorder
Interventions: DRUG: [11C]DPA-713
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sticky Bone Compared to A-PRF(Platlet Rich Fibrin) Effect on Alveolar Ridge Preservation
Status: COMPLETED
Conditions: A-PRF|ALLOGRAFT
Interventions: PROCEDURE: A-PRF|PROCEDURE: ALLOGRAFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perturbing of HIV Reservoir With Immune Stimulation
Status: COMPLETED
Conditions: AIDS|HIV
Interventions: BIOLOGICAL: Fluarix|BIOLOGICAL: Pneumovax|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing the Efficacy and Safety of Once-Daily Fuzeon (Enfuvirtide) Dosing Versus the Currently Recommended Twice-Daily Dosing in Human Immunodeficiency Virus-Type 1 (HIV-1) Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Optimized Background ARVs|DRUG: enfuvirtide [Fuzeon]|DRUG: enfuvirtide [Fuzeon]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma
Status: COMPLETED
Conditions: Grade IV Glioma|Grade IV Astrocytoma|Glioblastoma Multiforme
Interventions: BIOLOGICAL: TVI-Brain-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effective Treatments for Thoracic Aortic Aneurysms (ETTAA Study): A Prospective Cohort Study
Status: UNKNOWN
Conditions: Thoracic Aortic Aneurysm
Interventions: PROCEDURE: Stent Grafting (ESR)|PROCEDURE: Open Surgery (OSR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients
Status: RECRUITING
Conditions: Enterobacterial Infections|Oncologic Disease|Inflammatory Disease|Invasive Fungal Infections
Interventions: COMBINATION_PRODUCT: 18F-FDS PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanical Complications of Acute Myocardial Infarction During COVID-19 Pandemics
Status: COMPLETED
Conditions: Ventricular Septal Rupture|Papillary Muscle Rupture|Free Wall Rupture, Heart
Interventions: PROCEDURE: Surgical repair|PROCEDURE: Percutaneous treatment|PROCEDURE: Mitral valve surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Obinutuzumab|DRUG: Venetoclax|DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetaphil Restoraderm Effect on Young Children With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Cetaphil® Restoraderm® moisturizer + Cetaphil® Restoraderm® body wash|OTHER: Cetaphil® Restoraderm® body wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Deep Brain Stimulation of the Nucleus Accumbens and the Ventral Anterior Internal Capsule for Severe Alcohol Addiction
Status: UNKNOWN
Conditions: Addiction
Interventions: OTHER: Deep brain stimulation|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consolidation Sintilimab After Concurrent Chemoradiation in Patients With Unresectable Stage III NSCLC
Status: UNKNOWN
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: Consolidation Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Budesonide Hydrofluoroalkane (HFA) vs Chlorofluorocarbon (CFC) Pressurized Metered Dose Inhalers (pMDI) in Patients With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide HFA|DRUG: Budesonide CFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of TPV/r to DRV/r in Triple Class Experienced Patient With Resistance to > 1 PI
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Tipranavir|DRUG: Darunavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b|Tetanus|Hepatitis B|Whole Cell Pertussis|Diphtheria|Poliomyelitis Vaccines
Interventions: BIOLOGICAL: GSK2036874A vaccine|BIOLOGICAL: Zilbrix™/Hib vaccine|BIOLOGICAL: Poliorix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Music Therapy on the Anxiety Level of Patients During the Administration of Ocular Intravitreal Injections
Status: COMPLETED
Conditions: Anxiety and Fear
Interventions: OTHER: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective and Comparative Evaluation of a Medical Device Composed of a Perineal Probe Connected to a Mobile Application in the Management of Stress Urinary Incontinence.
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence
Interventions: DEVICE: EMY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albumin-Bound Paclitaxel Combined With Carboplatin as Neoadjuvant Chemotherapy in Luminal B/HER-2 Negative Breast Cancer
Status: UNKNOWN
Conditions: HER-2 Negative Breast Cancer
Interventions: DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window (ImpACT-24A)
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Active Stimulation|DEVICE: Sham Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DY002: Safety and Effectiveness of DYME as an Agent for Selective Staining of the Anterior Capsule During Cataract Surgery
Status: TERMINATED
Conditions: Mature Cataracts
Interventions: DRUG: DYME|DRUG: DYME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cesarean Scar Pregnancy Managed by Dilatation and Evacuation (D&E) Versus Hysteroscopic Surgery
Status: UNKNOWN
Conditions: Scar; Previous Cesarean Section
Interventions: PROCEDURE: hysteroscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Efficacy Study of MP-214 in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Cariprazine 3 mg|DRUG: Cariprazine 6 mg|DRUG: Cariprazine 12.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of in Situ Regeneration of Endometrium
Status: RECRUITING
Conditions: Infertility, Female, of Uterine Origin|Endometrial Fibrosis
Interventions: DRUG: CBD-bFGF|DRUG: Collagen/BMMNCs|DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ibrutinib|DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of n-3 LCPUFA on Immune Function and Cardiovascular Risk Factors
Status: UNKNOWN
Conditions: Cardiovascular Heart Disease|Metabolic Syndrome
Interventions: BEHAVIORAL: Fish oil (Bio-Marine, Pharma Nord)|BEHAVIORAL: n-6 PUFA intake (Margarine+sunflower oil vs. butter product+rapeseed oil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Intracuff Alkalinized Lidocaine on Coughing Incidence at Extubation
Status: COMPLETED
Conditions: Coughing|Extubation|Lidocaine|Endotracheal Cuff
Interventions: PROCEDURE: Endotracheal intubation with injection of liquid in the cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Value of HS-CRP in Stable Angina.
Status: COMPLETED
Conditions: Stable Angina|Positive ETT
Interventions: PROCEDURE: coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC