pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of Mobile Teledermatology in the Care of Acne Patients
Status: COMPLETED
Conditions: Acne
Interventions: OTHER: Mobile Teleconsultation Arm (MTA)|OTHER: Outpatient Consultation Arm (OCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Appropriate Laryngeal Mask Airway Size in Patients With Overweight: A Comparison of the Actual Body Weight and Ideal Body Weight
Status: COMPLETED
Conditions: General Anesthesia
Interventions: DEVICE: actual body weight based size|DEVICE: ideal body weight based size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Reasons and Consequences of Bleeding in Late Teens and Early Adulthood Patients With Severe Hemophilia A
Status: COMPLETED
Conditions: Hematologic Disease|Blood Coagulation Disorders
Interventions: BEHAVIORAL: Recombinant Factor VIII (Kogenate, BAY 14-2222)|BEHAVIORAL: Recombinant Factor VIII (Kogenate, BAY 14-2222)|BEHAVIORAL: Recombinant Factor VIII (Kogenate, BAY 14-2222)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-inflammatory Steroids in the Prevention of Tooth Sensitivity
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: Dexamethasone acetate|DRUG: Potassium Nitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Electrical Stimulation in the Treatment of Acute Anxiety Induced by Stressful Life Events: A Pilot Study
Status: UNKNOWN
Conditions: Anxiety
Interventions: DEVICE: NeuroConn DC Stimulator Plus tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of MP-424, Interferon Beta (IFN Beta), and Ribavirin(RBV) in Treatment-Naïve or Having Received Interferon Based Therapy With Chronic Hepatitis C (CHC)
Status: COMPLETED
Conditions: Chronic Hepatitis C(CHC)
Interventions: DRUG: MP-424|DRUG: RBV(24 weeks)|DRUG: IFN beta(24 weeks)|DRUG: RBV(48 weeks)|DRUG: IFN beta(48 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orchestra in Class, a Novel Booster for Executive Functions and Brain Development in Young Primary School Children
Status: RECRUITING
Conditions: Development, Child|Executive Functions|Interventions|Music|Arts|Brain Plasticity|Behavior|Brain Imaging|Magnetic Resonance Imaging|Functional Magnetic Resonance Imaging|Structural Brain Connectivity
Interventions: BEHAVIORAL: Orchestra in Class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Renal and Digestive Tolerance of a Food Supplement, Phytalgic, in Elderly Volunteers - A Multicentric Open Trial
Status: COMPLETED
Conditions: Renal Tolerance|Digestive Tolerance
Interventions: DIETARY_SUPPLEMENT: Phytalgic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Contribution of Muscle and Disc Elastography in the Evaluation of Biomechanical Modifications of the Neuromuscular Spine Fixed by Bipolar Construct
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuromuscular Scoliosis
Interventions: OTHER: Ultrasound elastography (USE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Pulmonary Vein Isolation With the Cryoballoon and Radiofrequency Energy(Contact Force) in the Treatment of Persistent Atrial Fibrillation (AF) (Cryo Vs CF in PerAF)
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Cryoballoon|DEVICE: Radiofrequency Energy(Contact Force)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ITCA 650 Compared to Sitagliptin as add-on Therapy for the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ITCA 650 60 mcg/day|DRUG: sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Scan-Guided Watchful Waiting or Neck Dissection of Locally Advanced Lymph Node Metastases in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Primary Head And Neck Cancer
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: positron emission tomography/computed tomography|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Open Label Phase Two Study of Enzalutamide With Concurrent Administration of Radium Ra 223 Dichloride in Castration-Resistant (Hormone-Refractory) Prostate Cancer Subjects With Symptomatic Bone Metastasis
Status: COMPLETED
Conditions: Prostate Carcinoma Metastatic to the Bone
Interventions: DRUG: Enzalutamide|RADIATION: Radium ra 223 dichloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopurinol to Prevent Cirrhosis Related Morbidities
Status: COMPLETED
Conditions: Cirrhosis
Interventions: DRUG: Placebo|DRUG: Allopurinol 300 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Supplementation With Vitamin D Improves Leptin Resistance
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate
Status: COMPLETED
Conditions: Transurethral Prostatectomy
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: PROCEDURE: Implantation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss
Status: COMPLETED
Conditions: Obesity|Weight Loss
Interventions: DIETARY_SUPPLEMENT: Weight loss group (Full meal replacement products)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Role of a New Prosthodontics Device in Hard and Soft Tissue Changes After Subcrestal Implant Placement
Status: COMPLETED
Conditions: Edentulous Alveolar Ridge
Interventions: DEVICE: Gingival Former Abutment|PROCEDURE: Subcrestal Implant|DEVICE: Healing Abutment|DEVICE: Prosthetic Crown|PROCEDURE: Crestal Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
Status: COMPLETED
Conditions: Opiate Addiction|Medication Non-adherence|Addiction|Opioid Dependence
Interventions: DEVICE: AiCure monitoring and intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Internal Radiation Therapy and 188Re-SSS Lipiodol Treatment for Liver Cancer (Lip-Re2)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: COMBINATION_PRODUCT: Selective Internal Radiation Therapy with 188Re-SSS lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Bimatoprost 0.01% in Primary Open-Angle Glaucoma (POAG) or Ocular Hypertension (OH)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Bimatoprost 0.01%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Abscess|Wound Infection|Surgical Site Infection|Cellulitis
Interventions: DRUG: Dalbavancin|DRUG: Dalbavancin-matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Electrophysiological Evaluation of the Effectiveness for Manual Lymphatic Drainage
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Electrophysical Evaluation|Manual Lymphatic Drainage
Interventions: OTHER: manual lymphatic drainage (massage)|OTHER: Splint treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine and Rituximab for the Treatment of Splenic Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Marginal Zone B-cell Lymphoma
Interventions: DRUG: Bendamustine and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
Status: COMPLETED
Conditions: Infertility, Female
Interventions: OTHER: SSA sperm selection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pasta Formulations, Portion Sizes and Their Effect on Appetite
Status: COMPLETED
Conditions: Healthy|Appetite
Interventions: OTHER: Control, small|OTHER: Experimental B, small|OTHER: Experimental pasta C, small|OTHER: control, medium|OTHER: experimental pasta B, medium|OTHER: experimental pasta C, medium|OTHER: NL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICC
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: oxaliplatin , fluorouracil, and leucovorin|DRUG: gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of MK-1602 in the Treatment of Acute Migraine (MK-1602-007)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: MK-1602|DRUG: Placebo|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E for Extremely Preterm Infants
Status: COMPLETED
Conditions: Infant, Newborn|Infant, Small for Gestational Age|Infant, Very Low Birth Weight|Infant, Premature|Intracranial Hemorrhages
Interventions: DRUG: Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Autologous Mesenchymal Stem Cell Transplantation (Effects and Side Effects) in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: intravenous injection of mesenchymal stem cells|BIOLOGICAL: injection of cell free media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Timi3 Ultrasound on Myocardial Blow Flow in the Hibernating Myocardium
Status: TERMINATED
Conditions: Myocardial Ischemia
Interventions: DEVICE: Timi3 Transthoracic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Simvastatin (Zocor)|DRUG: 10mg/10mg of Ezetimibe/Simvastatin (Vytorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccination Perception in Inflammatory Conditions - Flu, Pneumonia and COVID-19
Status: COMPLETED
Conditions: Inflammatory Disease|Rheumatoid Arthritis|Psoriatic Arthritis|Systemic Lupus Erythematosus|Ankylosing Spondylitis|Vasculitis|Reactive Arthritis|Inflammatory Bowel Diseases
Interventions: OTHER: Semi-structured qualitative interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers
Status: COMPLETED
Conditions: Phase 1
Interventions: DRUG: PF-04965842|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anxiety in Parkinson's: Use of Quantitative Methods to Guide Rational Treatment
Status: TERMINATED
Conditions: Anxiety Disorders|Parkinson Disease
Interventions: DRUG: rotigotine transdermal patch|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Small Airway Function of Fluticasone/Formoterol (Flutiform®) and Fluticasone/Salmeterol
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Fluticasone/Formoterol|DRUG: Fluticasone/Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of AR-67 (7-t-butyldimethylsilyl-10-hydroxycamptothecin) Given on Days 1, 4 8, 12 & 15 of an Every 21-day Cycle in Adult Patients With Refractory or Metastatic Solid Malignancies
Status: COMPLETED
Conditions: Solid Malignancies
Interventions: DRUG: 7-t-butyldimethylsilyl-10-hydroxycamptothecin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib and Docetaxel in Metastatic Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: Dasatinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specific Versus Empirical Anthelminthic Treatment in Eosinophilia
Status: NOT_YET_RECRUITING
Conditions: Eosinophilia
Interventions: DRUG: Albendazole|DRUG: Ivermectin or albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-flow Nasal Cannula and Exercise Tolerance in COPD
Status: COMPLETED
Conditions: COPD|Rehabilitation|Exercise
Interventions: OTHER: High flow nasal therapy|OTHER: Non-invasive ventilation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Investigation to Assess the Effectiveness of Benzocaine Condoms in Healthy Adult Men
Status: WITHDRAWN
Conditions: Ejaculation Delayed
Interventions: DEVICE: Test condom A (NRL condom with 5% benzocaine paste)|DEVICE: Test condom B (NRL condom with 3% benzocaine paste)|DEVICE: Control NRL condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multidisciplinary Return-to-work Rehabilitation and Return-to Work Follow-up
Status: COMPLETED
Conditions: Complex Symptom Disorders
Interventions: BEHAVIORAL: Return-to-work Rehabilitation + Follow up|BEHAVIORAL: Return-to-work rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genetic Testing Plus Irinotecan in Treating Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Primary CNS Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Primary Central Nervous System Non-Hodgkin Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Adult T-cell Leukemia/Lymphoma|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest
Status: COMPLETED
Conditions: Cardiopulmonary Arrest|Pediatric ALL|Resuscitation
Interventions: OTHER: AHA resuscitation sequence|OTHER: ERC resuscitation sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Regimen With QL1706 Plus Chemo ± Bev in PDAC Patients
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: QL1706|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fatigue in Lupus Intervention Programmes (FLIP)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Standard Care|BEHAVIORAL: 4 week FMP|BEHAVIORAL: 7 week FMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Loncastuximab tesirine 150 µg/Kg|DRUG: Loncastuximab tesirine 75µg/Kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Spesolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of TAT4 Gel for Reduction of Nasolabial Folds
Status: UNKNOWN
Conditions: Nasolabial Folds
Interventions: DRUG: TAT4 Gel|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Durvalumab(MEDI4736) + Tremelimumab in Pulmonary Sarcomatoid Carcinoma
Status: COMPLETED
Conditions: HNSCC|Head and Neck Neoplasms
Interventions: DRUG: Durvalumab,Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy
Status: RECRUITING
Conditions: Rectocele; Female|Pelvic Organ Prolapse
Interventions: COMBINATION_PRODUCT: posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venclose digiRF System Post Market Study
Status: ENROLLING_BY_INVITATION
Conditions: Venous Reflux|Chronic Venous Insufficiency
Interventions: DEVICE: Venclose System (digiRF generator w EVSRF catheter)|DEVICE: Venclose MAVEN System (digiRF generator w MAVEN catheter)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: Dolcanatide|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus
Status: COMPLETED
Conditions: Dyspepsia|Diabetes Mellitus With Gastrointestinal Symptoms
Interventions: DRUG: Exendin 9-39|DRUG: Microlipid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Focused Ultrasound and Exosomes to Treat Depression, Anxiety, and Dementias
Status: SUSPENDED
Conditions: Refractory Depression|Anxiety Disorders|Neurodegenerative Diseases
Interventions: OTHER: Exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Pre-Mixed Insulin With Insulin Glargine Combined With Rapid-Acting Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lispro Mixture Therapy|DRUG: Glargine Basal-Bolus Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Recombinant Human N-acetylgalactosamine 4-sulfatase (rhASB) in Patients With MPS VI
Status: COMPLETED
Conditions: Mucopolysaccharidosis VI
Interventions: DRUG: Placebo|DRUG: N-acetylgalactosamine 4-sulfatase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tapentadol vs Tramadol in Total Knee Arthroplasty
Status: RECRUITING
Conditions: Total Knee Replacement|Post-operative Pain|Chronic Pain
Interventions: DRUG: Tapentadol|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SUBLIVAC FIX Phleum Pratense DT/DRF
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: SUBLIVAC FIX phleum prat.|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-volume vs High-volume Polyethylene Glycol Based Bowel Preparation for Colonoscopy in People Receiving Hemodialysis
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Colon Polyp|Dialysis; Complications|Colon Cancer
Interventions: DRUG: 2-liters polyethylene glycol with citrate and simethicone|DRUG: 4-liters polyethylene glycol with simethicone|DIETARY_SUPPLEMENT: Low-residue diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung and Liver Disease|Infantile Liver Failure Syndrome 1|Neurologic, Endocrine and Pancreatic Disease, Multisystem, Infantile-Onset 2|Rajab Interstitial Lung Disease With Brain Calcifications 2
Interventions: OTHER: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Optimal Effect Site Concentration of Propofol for Conscious Sedation in Elderly Male Patients Undergoing Urologic Surgery Under Spinal Anesthesia With or Without Intrathecal Fentanyl
Status: COMPLETED
Conditions: Conscious Sedation Under Spinal Anesthesia
Interventions: DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Nutraceutical Properties and Health Benefits of Traditional Components of the Mediterranean Diet
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Hazelnuts|DIETARY_SUPPLEMENT: Chocolate|DIETARY_SUPPLEMENT: Red wine|DIETARY_SUPPLEMENT: Olive Oil|DIETARY_SUPPLEMENT: Wild mixed greens|DIETARY_SUPPLEMENT: Chestnut|OTHER: No Dietary Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: CBT for Adherence and Depression in Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Depression
Interventions: BEHAVIORAL: Enhanced treatment as usual plus adherence training|BEHAVIORAL: Enhanced treatment as usual plus CBT-AD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioactive Glass as Bone Graft Substitute in Operative Treatment of Bone - a 10 Years Follow-up Study
Status: COMPLETED
Conditions: Depressed Lateral Condyle Fracture|Benign Bone Tumour Cavity|Spinal Fusion
Interventions: DEVICE: Bioactive glass and/or autogenous bone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Intravitreal Ranibizumab for Persistent Diabetic Vitreous Haemorrhage:
Status: COMPLETED
Conditions: Diabetes Complications
Interventions: DRUG: Ranibizumab|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Abdominal Aortic Aneurysm Sac Embolization During EVAR
Status: NOT_YET_RECRUITING
Conditions: Abdominal Aortic Aneurysm Without Rupture
Interventions: DEVICE: EVAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TReatment of Pulmonary Hypertension Group II Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Hypertension (PH) Due to Left Heart Disease
Interventions: DEVICE: Pulmonary Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3, Multi-Center Study Evaluating PL9643 in Patients With Dry Eye
Status: UNKNOWN
Conditions: Dry Eye|Dry Eye Syndromes
Interventions: DRUG: Vehicle Opthalmic Solution|DRUG: PL9643 Opthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Orthostatic Intolerance
Status: ACTIVE_NOT_RECRUITING
Conditions: Tachycardia|Chronic Orthostatic Intolerance
Interventions: DRUG: Acetazolamide|DRUG: Atomoxetine|OTHER: NO Drug|DRUG: Clonidine|DRUG: Entacapone|DRUG: Entacapone & Propranolol|DRUG: Atomoxetine & Propranolol|DRUG: Indomethacin|DRUG: Mecamylamine|DRUG: Isosorbide Dinitrate|DIETARY_SUPPLEMENT: Melatonin|DRUG: Midodrine|DRUG: Modafinil|DRUG: Octreotide|RADIATION: Placebo|DRUG: Propranolol|DRUG: Modafinil & Propranolol|DRUG: Sertraline|PROCEDURE: IV Saline|OTHER: Drinking Water|DEVICE: Breathing Device|DRUG: memantine|DEVICE: Abdominal binder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Patient's Own AD-MSC and AD-HSC Transplantation in Patients With Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Severe Aplastic Anemia
Interventions: DRUG: Rabbit antithymoglobulin (ATG)|PROCEDURE: Adipose derived mesenchymal stem cells ( AD-MSCs)|PROCEDURE: AD-MSC transdifferentiated HSCs (AD-HSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Xyrem|DRUG: Xyrem Placebo|DRUG: Modafinil at established dose|DRUG: Modafinil (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CMP-CPS-001 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: CMP-CPS-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tui-na and Oral Chinese Medicine on KOA
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Tui-na|DRUG: Du-Huo-Ji-Sheng-Tang (DHJST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancement of Residual Limb Proprioception and Rehabilitation Training Methods With a Vibrotactile Device.
Status: UNKNOWN
Conditions: Transtibial Amputation
Interventions: BEHAVIORAL: Internal Focus of Attention|BEHAVIORAL: External Focus of Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Autologous Cord Blood Mononuclear Cells for Prevention of Bronchopulmonary Dysplasia or Death in Extremely Preterm Neonates
Status: RECRUITING
Conditions: BPD
Interventions: BIOLOGICAL: autologous cord blood mononuclear cells|BIOLOGICAL: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy, Irinotecan, and Cetuximab in Treating Patients Who Are Undergoing Surgery for Stage III or Stage IV Rectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: irinotecan hydrochloride|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Effects of Salvia Miltiorrhiza Extract (Danshen)
Status: UNKNOWN
Conditions: Dyslipidemias|Hypertension|Vasodilation|Oxidative Stress|Inflammation
Interventions: DIETARY_SUPPLEMENT: Salvia miltiorrhiza extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal Intubation
Status: RECRUITING
Conditions: Intubation, Intratracheal|Adverse Effects
Interventions: DRUG: Ciprofol|DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction
Status: RECRUITING
Conditions: Refractive Errors
Interventions: DIAGNOSTIC_TEST: Mobile medical application to self administer a subjective refraction test|DIAGNOSTIC_TEST: Standard of care refraction test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Volociximab in Combination With DTIC in Patients With Metastatic Melanoma Not Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Melanoma|Metastases
Interventions: DRUG: M200 (volociximab) in Combination with Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Conditioning on Bimanual Skill Learning and Corticospinal Excitability in Children With Unilateral Cerebral Palsy
Status: RECRUITING
Conditions: Unilateral Cerebral Palsy
Interventions: BEHAVIORAL: Bimanual Cup Stacking Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅰ Clinical Trial of Gerilimzumab Injection in Healthy Subjects
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: GB224 2mg|BIOLOGICAL: GB224 5mg|BIOLOGICAL: GB224 10mg|BIOLOGICAL: GB224 15mg|BIOLOGICAL: GB224 20mg|BIOLOGICAL: GB224 30mg|OTHER: Placebo, 2mg|OTHER: Placebo, 5mg|OTHER: Placebo, 10mg|OTHER: Placebo, 15mg|OTHER: Placebo, 20mg|OTHER: Placebo, 30mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Westmead Feelings Program Intervention for Chinese Children With Autism Spectrum Disorder in Hong Kong
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: The Hong Kong version of Westmead Feeling Program 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronically-infected HCV Genotype 2 and 3 Treatment-naive Subjects: Part A: Safety and Efficacy of INX-08189 With Peg IFN Alfa-2a and Ribavirin. Part B: INX-08189 in Interferon Free Treatment With Daclatasvir and/or Ribavirin
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: INX-08189|DRUG: INX-08189|DRUG: INX-08189|DRUG: Placebo matching with INX-08189|BIOLOGICAL: Pegylated interferon alfa-2a|DRUG: Ribavirin|DRUG: INX-08189|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The High Density Lipoprotein and Endothelial Function, Niacin and Nitric Oxide Study (The High-Ennd Study)
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Extended-Release Niacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars
Status: COMPLETED
Conditions: Decay, Dental|Impacted Third Molar Tooth
Interventions: DIAGNOSTIC_TEST: Radiologic examination on orthopantomogram|DIAGNOSTIC_TEST: Clinical examination after surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Smartphone App for Smoking Cessation in China
Status: COMPLETED
Conditions: Cigarette Smoking|Smartphone App-based Smoking Cessation
Interventions: BEHAVIORAL: smartphone app for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Training for Patients With Hypermobility Spectrum Disorders and Shoulder Symptoms: a Feasibility Study
Status: COMPLETED
Conditions: Hypermobility Syndrome Shoulder|Shoulder Pain Chronic
Interventions: OTHER: Progressive heavy shoulder resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant
Status: NOT_YET_RECRUITING
Conditions: Graft Vs Host Disease|Graft-versus-host-disease|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Non-hematologic Malignancy|Hematologic Malignancy
Interventions: DEVICE: CliniMACS® device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Rotigotine Patch Treatment on Cardiovascular Markers in Idiopathic Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)
Interventions: DRUG: Rotigotine|DRUG: Placebo patchs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Low Blood Pressure in Persons With Tetraplegia
Status: COMPLETED
Conditions: Hypotension|Spinal Cord Injury
Interventions: DRUG: N-Nitro L-arginine-methylester (L-NAME)|PROCEDURE: Head-up Tilt maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nutritional Supplement VIUSID/ALZER in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DIETARY_SUPPLEMENT: VIUSID/ALZER|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Recreational Games on Happiness, Life Satisfaction, Loneliness, and Somatisation in Elderly Individuals
Status: COMPLETED
Conditions: Happiness|Life Satisfaction|Loneliness|Somatization
Interventions: BEHAVIORAL: Recreational Games
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: Bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: 25 mg PF-04991532|DRUG: 75 mg PF-04991532|DRUG: 150 mg PF-04991532|DRUG: 300 mg PF-04991532|DRUG: Sitagliptin 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Status: COMPLETED
Conditions: Paresis
Interventions: DRUG: Ropivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Effect of Giving Dulaglutide Using an Auto-injector Versus a Manual Syringe
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: Dulaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Analysis of Right Ventricular Remodeling in Response to Prolonged Strength Training Using 3D-echocardiography
Status: COMPLETED
Conditions: Cardiac Remodeling, Ventricular|Right Ventricular Hypertrophy
Interventions: OTHER: Strength physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Occlusal Stabilization Splints Equilibrated by Different Techniques and Their Effect on TMD
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders
Interventions: DEVICE: occlusal stabilization splints
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)
Status: COMPLETED
Conditions: Infectious Disease
Interventions: DRUG: MK-7655|DRUG: Imipenem + Cilastatin|DRUG: Caffeine|DRUG: Midazolam|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV
Status: UNKNOWN
Conditions: COPD Exacerbation|Noninvasive Ventilation|Long Term Oxygen Therapy|Chronic Respiratory Failure
Interventions: OTHER: Protocol for structured discharge and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 12 Week Study of the Safety/Efficacy of Asenapine When Added to Lithium/Valproate in the Treatment of Bipolar Disorder (A7501008 / P05844 / MK-8274-017)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Asenapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicorandil on Cardiac Infarct Size in Patients With ST-segment Elevation Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Nicorandil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block Versus Erector Spinae Plane Block
Status: COMPLETED
Conditions: Postoperative Pain|Laparotomy
Interventions: PROCEDURE: transversus abdominis plane block|PROCEDURE: erector spinae plane block|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacogenomics for Improving Pediatric ADHD Treatment
Status: TERMINATED
Conditions: Attention Deficit Disorders With Hyperactivity
Interventions: DIAGNOSTIC_TEST: Pharmacogenomics report
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure
Status: COMPLETED
Conditions: Obesity|Pre-hypertension|Hypertension
Interventions: OTHER: Resistance exercise training|OTHER: Hypocaloric diet|OTHER: Resistance exercise training & diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Performance of the SPIRION Laryngeal Pacemaker in BVFP Patients Without Glottal Enlargement
Status: RECRUITING
Conditions: Bilateral Vocal Cord Paralysis
Interventions: DEVICE: SPIRION Laryngeal Pacemaker System Implantation and follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Human protein C concentrate|DRUG: Activated protein C|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase1, Placebo-Controlled, Randomized, Double-blind, Single-ascending Dose Study in Healthy Subjects.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: S1226 (4%)|DRUG: Saline (for 4%)|DRUG: S1226(8%)|DRUG: Saline (for 8%)|DRUG: S1226(12%)|DRUG: Saline (for 12%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: