pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Soft Tissue Mobilization Techniques on PMS
Status: RECRUITING
Conditions: Premenstrual Syndrome|Premenstrual Pain|Chronic Pelvic Pain
Interventions: OTHER: Progressive Muscle Relaxation Group:|OTHER: Myofascial Release Technique Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Of A Physiotherapy Treatment Plan In Lateral Epicondylalgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Humeral Epicondylitis, Lateral
Interventions: DEVICE: Dry needling|DEVICE: Topical gel|DRUG: NSAIDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mexiletine in Sporadic Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Sporadic Amyotrophic Lateral Sclerosis
Interventions: DRUG: Mexiletine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: CNTX-4975
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monotherapy IVIG Gamunex-C for HMG-CoA Reductase Auto-Antibody Positive Necrotizing Myopathy Treatment (The MIGHT Trial)
Status: WITHDRAWN
Conditions: Immune-Mediated Necrotizing Myopathy
Interventions: DRUG: Gamunex-C|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Vibration Versus Functional Strength Training On Balance In Children With Hemiparetic Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Hemiparesis
Interventions: DEVICE: whole body vibration|OTHER: Functional strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Stage III Fallopian Tube Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Primary Peritoneal Cancer AJCC v7|Stage IIIA Fallopian Tube Cancer AJCC v7|Stage IIIA Ovarian Cancer AJCC v6 and v7|Stage IIIA Primary Peritoneal Cancer AJCC v7|Stage IIIB Fallopian Tube Cancer AJCC v7|Stage IIIB Ovarian Cancer AJCC v6 and v7|Stage IIIB Primary Peritoneal Cancer AJCC v7|Stage IIIC Fallopian Tube Cancer AJCC v7|Stage IIIC Ovarian Cancer AJCC v6 and v7|Stage IIIC Primary Peritoneal Cancer AJCC v7|Stage IV Fallopian Tube Cancer AJCC v6 and v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Primary Peritoneal Cancer AJCC v7
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|BIOLOGICAL: Pembrolizumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Low-value Care for Trauma Admissions
Status: NOT_YET_RECRUITING
Conditions: Trauma Injury
Interventions: BEHAVIORAL: Audit & feedback with educational outreach and facilitation|BEHAVIORAL: Simple audit & feedback (usual practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stereotactic Magnetic Resonance Guided Radiation Therapy
Status: SUSPENDED
Conditions: Pancreas Cancer|Lung Cancer|Renal Cancer|Adrenal Metastases|Prostate Cancer|Liver Metastases|Oligoprogressive Nodal Metastases|Metachronous Nodal Metastases|Synchronous Nodal Metastases|Mesothelioma|Spine Metastases|Brain Metastases|Borderline Resectable Pancreatic Carcinoma
Interventions: RADIATION: MR-guided Linac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Study of Efficacy and Safety of Clevudine
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Clevudine|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: ifosfamide|DRUG: mesna|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Study of the Effects of Serum and Follicular Fluid Relaxin Levels on Ovarian Function in IVF Cycles"
Status: COMPLETED
Conditions: Infertility|Reproductive Techniques, Assisted|Oocyte Maturation
Interventions: DIAGNOSTIC_TEST: Relaxin ELISA Kit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Phase IIa Study of CVXL-0107 in Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson Disease
Interventions: DRUG: CVXL-0107|DRUG: Placebo|DRUG: Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
Status: RECRUITING
Conditions: Frail Elderly Syndrome|Primary Prevention|Postoperative Delirium|Frailty
Interventions: OTHER: Non-pharmacological intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Non Hodgkin Lymphoma
Interventions: DRUG: IPH6501
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LXI-15028 Comparing With Lansoprazole in the Treatment of Duodenal Ulcer
Status: COMPLETED
Conditions: Duodenal Ulcer
Interventions: DRUG: LXI-15028 50mg group|DRUG: Lansoprazole 30mg group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy
Status: RECRUITING
Conditions: Thymoma|Thymic Carcinoma
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial to Assess the Feasibility of Implementing Objective Parameters in Patients Affected by Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: patients assuming nutraceutical containing HA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Halophyte-based Cream on Pain and Itch
Status: COMPLETED
Conditions: Pain, Acute|Itch
Interventions: OTHER: Halophites-based cream 24 hours|OTHER: Halophites-based cream 48 hours|OTHER: Vehicle cream 24 hours|OTHER: Vehicle cream 48 hours|OTHER: Histamine 1%|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-cesarean Post Placental Introducer Withdrawal IUD Insertion Technique
Status: COMPLETED
Conditions: Intrauterine Contraceptive Device Complication
Interventions: PROCEDURE: IUD insertion during cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: iRF System Hepatic Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety of and Immune Response to the PENNVAX-B DNA Vaccine With and Without IL-12 in HIV-uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PENNVAX-B|BIOLOGICAL: IL-12 DNA plasmids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Levetiracetam Intravenous 15 Minute Infusion in Subjects Suffering From Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clobetasol Propionate 0.05% Shampoo in Association With Antifungal Shampoo in Scalp Seborrheic Dermatitis
Status: COMPLETED
Conditions: Scalp Seborrheic Dermatitis
Interventions: DRUG: clobetasol propionate shampoo (4/week) - ketoconazole shampoo (2/week)|DRUG: clobetasol propionate shampoo (2/week) - ketoconazole shampoo (2/week)|DRUG: clobetasol propionate shampoo (2/week)|DRUG: ketoconazole shampoo (2/week)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using High-flow Nasal Oxygen-delivery System in Patients Under Intravenous General Anesthesia
Status: UNKNOWN
Conditions: Pulmonary Atelectases|Lung Injury|General Anesthesia
Interventions: DEVICE: high-flow nasal oxygen|DEVICE: Oxygen mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acute Exercise Type and Cognitive Function: An Event-related Potential Study
Status: UNKNOWN
Conditions: Exercise Training|Neurocognitive Function
Interventions: BEHAVIORAL: aerobic exercise group (AE)|BEHAVIORAL: aerobic exercise with virtual reality group (AE-VR)|BEHAVIORAL: combined exercise group (CE)|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bilateral Transversus Thoracic Muscle Plane Block as Analgesic in Open Heart Surgeries by US.
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: 0.25% bupivacaine.|DEVICE: 0.9%saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regorafenib and Cetuximab in Patients With Advanced Malignancy
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: Regorafenib|DRUG: Cetuximab|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Psychological Group Interventions
Status: UNKNOWN
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Online Group CBT intervention|BEHAVIORAL: SilverCloud guided|BEHAVIORAL: SilverCloud Unguided|BEHAVIORAL: Mood Flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Differentiated Resistance Training of the Paravertebral Muscles in Patients With Unstable Spinal Bone Metastasis Under Concomitant Radiotherapy
Status: UNKNOWN
Conditions: Vertebral Bony Metastases
Interventions: OTHER: Isometric resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Busulfan|DRUG: Cladribine|DRUG: Fludarabine Phosphate|PROCEDURE: Hematopoietic Cell Transplantation|DRUG: Thiotepa|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Head and Neck Cancer|Esophageal Cancer|Other Metastatic Solid Tumors
Interventions: DRUG: JAB-3068
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laryngeal Mask Cuff Pressure in Geriatric Patients
Status: COMPLETED
Conditions: Anaesthesia
Interventions: PROCEDURE: The placement according to the manufacturer's instructions|PROCEDURE: Cuff inner pressure was held below 44 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Ankle Arthrodesis Nail for 2-level Pathologic Tibial Fracture
Status: UNKNOWN
Conditions: Bone Metastases|Fracture Nonunion|Bone Lesion
Interventions: PROCEDURE: osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PLASMA 2 Trial: Examination of Once Daily (QD) Dosing of A-002 In Subjects With Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: A-002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP Pancreatitis
Status: RECRUITING
Conditions: Post-ERCP Acute Pancreatitis
Interventions: DRUG: Tacrolimus capsule|DRUG: Placebo|DRUG: Rectal Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rotator Cuff Repair With Magnesium Pin
Status: NOT_YET_RECRUITING
Conditions: Arthroscopic Rotator Cuff Repair
Interventions: PROCEDURE: magnesium pin in additional to the suture anchor|PROCEDURE: routine suture anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)
Status: TERMINATED
Conditions: Advanced Cancer|Pancreatic Cancer|Renal Cell Cancer|Non Small Cell Lung Cancer|Colorectal Carcinoma|Endometrial|Uterine
Interventions: DRUG: Temsirolimus|DRUG: Irinotecan|DRUG: Irinotecan + capecitabine|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: Extended Vision IOL|DEVICE: Neutral Aspheric Monofocal IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration
Status: COMPLETED
Conditions: Cancer Pain
Interventions: DRUG: PCA IV Hydromorphone (continuous dose = 0)|DRUG: PCA IV Hydromorphone (continuous dose ≠ 0)|DRUG: Oral morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Clinical Study of the Pharmacokinetics and Safety of Elsulfavirine, 200 mg Tablets, With Single and Multiple Oral Administration in Healthy Volunteers
Status: COMPLETED
Conditions: Covid19|HIV-1-infection
Interventions: DRUG: Elsulfavirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma|Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Metformin|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Posterior Oblique Sling Strengthening Exercises on Pain & Flexibility Among Runners With
Status: RECRUITING
Conditions: Iliotibial Band Syndrome
Interventions: OTHER: Hip abductors stretching and strengthening exercises|OTHER: Posterior oblique sling strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Augmented Reality on Dental Anxiety and Pain Perception in Children
Status: ENROLLING_BY_INVITATION
Conditions: Anxiety|Pain
Interventions: BEHAVIORAL: Distraction by dentist|BEHAVIORAL: Distraction by cartoon movie|BEHAVIORAL: AG-active distraction group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transient Elastography DEdicated to Cosmetology And Dermatology (TEDECAD)
Status: COMPLETED
Conditions: Venous Insufficiency|Lymphedema
Interventions: DEVICE: Cutometer|DEVICE: High resolution ultrasonography (echography)|DEVICE: Elastography|PROCEDURE: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation
Status: UNKNOWN
Conditions: Patient With Nasolacrimal Duct Obstruction|External Dacryocystorhinostomy Operation
Interventions: DRUG: Bupivacaine|DRUG: Nitroglycerine|DRUG: Propofol|DRUG: Fentanyl|DRUG: Atracurium Besylate|PROCEDURE: Mechanical ventilation|DRUG: Sevoflurane|DRUG: Lactated Ringers|OTHER: Head-up tilt|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Activation of the Sphingosine-1-phosphate (S1P) to S1P1 Receptor Subtype (S1PR1) Axis in Patients With Endometriosis: Identification of Potential Relevant Biomarkers to Diagnose and Treat
Status: COMPLETED
Conditions: Endometriosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of PRP Treatment to the IA vs. IA and EA Environments in Patients Diagnosed With Hip Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis, Hip|Osteoarthritis|Degeneration
Interventions: BIOLOGICAL: Leukocyte-poor platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
Status: COMPLETED
Conditions: Covid19|Kidney Transplant Infection|Risk Factor, Cardiovascular|Immunosuppression|Outcome, Fatal|Graft Failure
Interventions: OTHER: Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience from the Middle East
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Polychemotherapy With XELOXIRI-3 in Elderly or Frail Patients With Advanced Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: XELOXIRI-3|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Community Based Depression Management and Child Development
Status: COMPLETED
Conditions: Maternal Depressive Symptom and Child Development
Interventions: BEHAVIORAL: Cognitive behavioral therapy: Alter of negative thinking, positive thinking and social support and psychosocial stimulation: play stimulation and parenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune Diseases
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus (SLE)|Sjogren's Syndrome|Systemic Sclerosis|Inflammatory Myopathy|ANCA Associated Vasculitis|Antiphospholipid Syndrome
Interventions: BIOLOGICAL: anti-CD19-CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep braIn Stimulation for Tremor TractographIC Versus Traditional
Status: UNKNOWN
Conditions: Essential Tremor
Interventions: DEVICE: Conventional AC-PC based implantation of ACTIVA INS DBS system|DEVICE: MR-tractography guided implantation of ACTIVA INS DBS system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Methadone Maintenance Treatment Outcome Study in Three Provinces in China
Status: COMPLETED
Conditions: HIV|Hepatitis C|Syphilis|Herpes Simplex Type II
Interventions: BEHAVIORAL: MMT provider dosage training|BEHAVIORAL: targeted counseling|OTHER: national guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Comparison of Two Daily Disposable Contact Lenses
Status: COMPLETED
Conditions: Refractive Errors
Interventions: DEVICE: Verofilcon A contact lenses|DEVICE: Somofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Low Molecular Weight Heparins in Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: LMWH|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Atrial ablation for subject scheduled for a de novo endocardial ablation of symptomatic, drug-refractory PsAF.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alteration of Deep Brain Stimulation Parameters for Dystonia
Status: UNKNOWN
Conditions: Dystonia
Interventions: PROCEDURE: Alteration of deep brain stimulator settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Association Between CYP2D6 Genetic Polymorphisms and the Treatment Effect of Tamoxifen
Status: TERMINATED
Conditions: Breast Cancer|Metastatic Disease
Interventions: DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Type VI Secretion System in Klebsiella Pneumoniae
Status: RECRUITING
Conditions: Detection of Type VI Secretion System in K.Pneumoniae|Detection of Relation to Ab Resistance, Biofilm
Interventions: DIAGNOSTIC_TEST: Routine bacteriological cultures|DIAGNOSTIC_TEST: Identification of the organism and antibiotic sensitivity will be done by VITEK II|DIAGNOSTIC_TEST: Detection of biofilm formation|DIAGNOSTIC_TEST: Molecular detection by PCR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Efficacy and Safety Evaluation of Irbesartan and Amlodipine Combined Therapy in Essential Hypertension Patients
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Irbesartan/Amlodipine low|DRUG: Irbesartan/Amlodipine high|DRUG: Irbesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy Plus Root Debridement in Gum Disease Treatment V2
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: light activated dye photodynamic therapy (PDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-mode Rehabilitation of Abdominal Tumor Patients Undergoing Concurrent Chemoradiotherapy
Status: UNKNOWN
Conditions: Concurrent Chemoradiotherapy;Nutrition；Multimodal Rehabilitation
Interventions: BEHAVIORAL: Multimodal rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Ivermectin Mass Drug Administrations for MALaria Control II
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: DRUG: Ivermectin|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers
Status: COMPLETED
Conditions: Psychological Effects of Study Drug
Interventions: DRUG: Lactose (inactive placebo)|DRUG: 3,4-methylenedioxymethamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Application of ctDNA in Evaluation of Neoadjuvant Chemotherapy Efficacy and Exploration of Chemoresistance Mechanisms in Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Patients With Non-metastatic Pancreatic Cancer|Evaluation of Tumor Resectability Shall be Made in Consensus at Multidisciplinary Meetings, According to NCCN Guideline Version 1.2022 Pancreatic Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: ctDNA detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Actovegin in Post-stroke Cognitive Impairment (PSCI)
Status: COMPLETED
Conditions: Post-Stroke Cognitive Impairment (PSCI)
Interventions: DRUG: Actovegin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Diagnostics of Extraesophageal Reflux With the Restech System
Status: COMPLETED
Conditions: Nasal Diseases|Nasal Polyps|Laryngopharyngeal Reflux
Interventions: DEVICE: pH monitoring (Restech)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lung Deposition Via Different Inhalation Devices
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Pulmicort pMDI HFA|DRUG: Budesonide pMDI HFA|DRUG: Pulmicort Repulses|DRUG: Pulmicort Turbohaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cadonilimab Combined With Regorafenib as A Third-line Treatment in Patients With MSS CRLM
Status: RECRUITING
Conditions: CRC
Interventions: DRUG: Candonilimab (AK104)|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone/Pancreatic Clamp P&F
Status: WITHDRAWN
Conditions: Insulin Resistance|Prediabetic State|Non-Alcoholic Fatty Liver Disease|Overweight and Obesity
Interventions: DRUG: Insulin human|DRUG: Octreotide Acetate|DRUG: Glucagon|DRUG: Human Growth Hormone|DRUG: Dexamethasone Oral|OTHER: [6,6-2H2] D-glucose|DRUG: 20% D-glucose (aq)|DIETARY_SUPPLEMENT: BOOST Plus|DEVICE: Harvard Apparatus PHD ULTRA CP syringe pump|DEVICE: Yellow Springs Instruments (YSI) 2500 Biochemistry Glucose/Lactate Analyzer|OTHER: Normal saline|OTHER: Human albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: China Antihypertensive Trial in Acute Ischemic Stroke II
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: OTHER: Early antihypertensive treatment|OTHER: Delayed antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sequential CAR-T Cell Treating Leukemia Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Lymphoblastic Leukemia, in Relapse|Refractory Acute Lymphoid Leukemia
Interventions: BIOLOGICAL: chimeric antigen receptor T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOX6m Plus SIR-Spheres Microspheres vs FOLFOX6m Alone in Patients With Liver Mets From Primary Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: FOLFOX6m|DEVICE: SIR-Spheres microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women
Status: RECRUITING
Conditions: Arterial Hypertension|Postmenopausal; Menorrhagia|Cardiovascular Diseases
Interventions: BEHAVIORAL: Resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Combination Chemotherapy in Treating Patients With Previously Untreated Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle-Cell Lymphoma
Interventions: BIOLOGICAL: G-CSF|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Leucovorin|DRUG: Mesna|DRUG: Methotrexate|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Allograft Tolerance Through Mixed Chimerism
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DRUG: MEDI-507|DRUG: Rituximab|RADIATION: Total Body Irradiation|RADIATION: Thymic Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gingival Grafts During the Implantation Process on the Peri-implant Mucosa
Status: COMPLETED
Conditions: Dental Implants|Transplants
Interventions: OTHER: Efficacy of free gingival grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness|OTHER: Efficacy of connective tissue grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness|OTHER: No types of grafts will be made to improve the quality of the peri-implant mucosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Porcine Dermal Matrix in the Treatment of Multiple Adjacent Gingival Recessions
Status: COMPLETED
Conditions: Recession, Gingival
Interventions: PROCEDURE: Surgery 1|PROCEDURE: Surgery 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glass Ionomer Sealant Versus Fluoride Varnish on Occlusal Caries Prevention
Status: UNKNOWN
Conditions: Pit and Fissure Caries|Glass Ionomer Cements|Tooth, Deciduous|Child
Interventions: PROCEDURE: 5% sodium fluoride varnish (NaF)|PROCEDURE: Glass ionomer sealant (GIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: SmokefreeSGM|BEHAVIORAL: SmokefreeTXT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Behavioral Intervention To Improve Hypertension Control In Veterans
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: SMI|BEHAVIORAL: HEI|BEHAVIORAL: UC|BEHAVIORAL: SMI|BEHAVIORAL: HEI|BEHAVIORAL: UC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Fixation Technique On Thoracic Epidural Catheter Displacement
Status: RECRUITING
Conditions: Thoracic Epidural
Interventions: OTHER: Thoracic Epidural Catheter Fixation Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Comparing Two Established Gastrointestinal Suture Techniques - One-layer-continuous Versus Double-layer-continuous Suture
Status: TERMINATED
Conditions: Colo-colonic Anastomoses|Ileo-colonic Anastomoses
Interventions: PROCEDURE: double layer-suture|PROCEDURE: Single-layer suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humoral and Cellular Immune Responses After Influenza Vaccination in Patients With Postcancer Fatigue and in Patients With Chronic Fatigue Syndrome
Status: COMPLETED
Conditions: Postcancer Fatigue|Chronic Fatigue Syndrome
Interventions: BIOLOGICAL: Seasonal influenza vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Buprenorphine Maintenance Treatment of Opioid Dependence in Primary Care: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Opioid-Related Disorders|Heroin Dependence
Interventions: DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study in Chinese Children With a Low Level of Hormone to Grow. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day.
Status: COMPLETED
Conditions: Growth Hormone Deficiency in Children
Interventions: DRUG: somapacitan|DRUG: Norditropin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efavirenz-based Versus Nevirapine-based Antiretroviral Therapy Among HIV-infected Patients Receiving Rifampin
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: efavirenz|DRUG: nevirapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-organ Responses to CHronic Physical Activity and INactivity
Status: RECRUITING
Conditions: Sedentary Behavior|Metabolic Syndrome|Age-related Cognitive Decline|Age-Related Sarcopenia
Interventions: BEHAVIORAL: Decreased Physical Activity|BEHAVIORAL: Increased Physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study in Healthy Adults to Quantify Lung Deposition and Distribution of Radio-labelled S-770108 Inhalation Powder Formulation Delivered by a Novel Inhaler Device
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Radio-labelled S-770108|DEVICE: S-770108 Inhaler A1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer.
Status: COMPLETED
Conditions: Esophageal Anastomotic Leak|Tissue Pressure of Oxygen
Interventions: PROCEDURE: Preoperative Arterial Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influenza Challenge Study to Determine the Optimal Infection Dose and Safety of a Recombinant H3N2 (A/Texas/71/2017 (H3N2, Clade 3C3a) Influenza Strain
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza RG-A/Texas/71/2017 (H3N2) Challenge|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients
Status: COMPLETED
Conditions: Pruritis
Interventions: DRUG: Sarna|DRUG: Cetaphil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open-Label, Randomized Crossover Trial to Assess Subject Preference for Alprazolam Orally Disintegrating Tablets Compared to Conventional Alprazolam Tablets in Subjects With Anxiety
Status: COMPLETED
Conditions: ANXIETY
Interventions: DRUG: Alprazolam orally disintegrating tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Empagliflozin, Metformin HCl, Linagliptin (fixed dose combination)|DRUG: Empagliflozin|DRUG: Linagliptin|DRUG: Metformin HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: GENETIC: GINAKIT Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOX Chemotherapy Plus Fruquintinib and Sintilimab After First-line Treatment in Unresectable Hepatocellular Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Immunotherapy|Anti-angiogenic Therapy|FOLFOX Systemic Chemotherapy|Second-line Treatment
Interventions: DRUG: FOLFOX systemic chemotherapy plus fruquintinib and sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Messaging for Vaccination
Status: COMPLETED
Conditions: Vaccination Refusal|COVID-19 Pandemic
Interventions: BEHAVIORAL: Doctor Videos|BEHAVIORAL: Sharing Videos|BEHAVIORAL: Sharing Videos (Influencers)|BEHAVIORAL: Vaccine Ambassador|BEHAVIORAL: Video framing|BEHAVIORAL: Video order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of CHOP-R Followed by Zevalin and Rituxan in Follicular Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DRUG: Chemotherapy and Radioimmunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial Evaluating the Use of Fondaparinux in Percutaneous Coronary Intervention (PCI)(63133)(WITHDRAWN)
Status: WITHDRAWN
Conditions: Myocardial Infarction|Coronary Disease
Interventions: DRUG: fondaparinux sodium|DRUG: heparin|PROCEDURE: percutaneous coronary intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of KAI-9803 to Treat Subjects With ST Elevation Myocardial Infarction [Heart Attack]
Status: COMPLETED
Conditions: Myocardial Infarction|Cardiovascular Diseases|Pathologic Processes
Interventions: DRUG: KAI-9803
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes
Status: ACTIVE_NOT_RECRUITING
Conditions: Herpes Simplex
Interventions: BIOLOGICAL: Non-adjuvanted HSV formulation 1|BIOLOGICAL: Non-adjuvanted HSV formulation 2|BIOLOGICAL: Non-adjuvanted HSV formulation 3|BIOLOGICAL: HSV formulation 1 with adjuvant 1|BIOLOGICAL: HSV formulation 2 with adjuvant 1|BIOLOGICAL: HSV formulation 3 with adjuvant 1|BIOLOGICAL: HSV formulation 1 with adjuvant 2|BIOLOGICAL: HSV formulation 2 with adjuvant 2|BIOLOGICAL: HSV formulation 3 with adjuvant 2|DRUG: Placebo|BIOLOGICAL: HSVTI_F1|BIOLOGICAL: HSVTI_F2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Ginger Root|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gene Expression in Patients With Advanced or Metastatic Colorectal Cancer Receiving Bevacizumab
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: immunologic technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Risperidone Monotherapy in Ambulatory Bipolar Disorder With Concurrent Moderately Severe Anxiety and Lifetime Panic or Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Anxiety Disorder
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Nutritional Ketosis in VLCAD Deficiency
Status: COMPLETED
Conditions: VLCAD Deficiency|Fatty Acid Oxidation Defects
Interventions: DIETARY_SUPPLEMENT: ketone ester drink|BEHAVIORAL: exercise|PROCEDURE: muscle biopsy|DIAGNOSTIC_TEST: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Interventional Multidisciplinary Approach to Individualize Blood Pressure Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Uncontrolled Hypertension
Interventions: DIAGNOSTIC_TEST: Therapeutic drug monitoring|DEVICE: Home blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Liraglutide in Young Adults With Type 2 DIAbetes (LYDIA)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Cardiovascular Disease
Interventions: DRUG: Liraglutide|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Carbohydrate Consumption at Breakfast on Food Intake, Glycemic Response, and Subjective Appetite
Status: COMPLETED
Conditions: Childhood Obesity|Breakfast
Interventions: OTHER: Mashed potatoes|OTHER: Traditional breakfast|OTHER: Breakfast skipping|OTHER: French fries|OTHER: Beans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iloprost Power Disc-15 in Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Iloprost PD-6|DRUG: Iloprost PD-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Using Neoadj Chemo-Rad & EGFR-tyrosine Kinase Inhibitor for Potentially Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Tarceva
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT