pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Study of MP-435 in Combination With Methotrexate (MTX) in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MP-435(dose1) + Methotrexate|DRUG: Placebo + Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Food Supplementation With a Combined Food Supplement on Lipid Pattern, Indexes of Non-alcoholic Fatty Liver Disease and Systemic Inflammation
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human Single and Multiple Dose of GLPG1837
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1837 single ascending doses|DRUG: Placebo single dose|DRUG: GLPG1837 multiple ascending doses|DRUG: Placebo multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intracoronary Ad5FGF-4 in Patients With Stable Angina (AGENT-3)
Status: COMPLETED
Conditions: Angina Pectoris
Interventions: GENETIC: Ad5FGF-4 vs. Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MISSION-CJ for Justice-Involved Homeless Veterans
Status: RECRUITING
Conditions: Substance Use Disorder|Mental Health Disorder|Homelessness
Interventions: BEHAVIORAL: Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking- Criminal Justice|BEHAVIORAL: Maintaining Maintaining Independence and Sobriety through Systems Integration Outreach and Networking Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DEVICE: MagPro X100 Stimulator, B70 Fluid-Cooled Coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Human Anti-Cytomegalovirus Monoclonal Antibody
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: TCN-202|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS to Decrease Opioid Relapse (UG3)
Status: COMPLETED
Conditions: Opioid Dependence|Craving
Interventions: DEVICE: tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Proprioceptive Exercises in Soccer.
Status: UNKNOWN
Conditions: Knee Injuries
Interventions: OTHER: Routine training|OTHER: Routine training + proprioceptive exercise in warm-up|OTHER: Routine training + proprioceptive exercise in cool-down
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia
Status: COMPLETED
Conditions: Anesthesia, Spinal|Cesarean Section|Echocardiography|Cardiac Output
Interventions: RADIATION: Transthoracic Echocardiography|PROCEDURE: Spinal Anesthesia|DRUG: Intrathecal Bupivacaine|DRUG: Intrathecal Fentanyl|DRUG: Crystalloid Coload 1000 mL|PROCEDURE: Cesarean Delivery|DRUG: Intravenous Ephedrine|DRUG: Oxytocin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Hypnoacupuncture on Early Perioperative Recovery
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Acute Postoperative Pain
Interventions: OTHER: ACUPUNCTURE|OTHER: ANTIEMETICS|OTHER: NOTHING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial To Evaluate The Efficacy And Safety Of Fesoterodine In Patients With Symptoms Of Overactive Bladder Including Nocturnal Urinary Urgency
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Preceding LPS Administration on the Fluenz-induced Immune Response
Status: COMPLETED
Conditions: Innate Immune Response|Immune Tolerance
Interventions: BIOLOGICAL: Fluenz|OTHER: placebo|OTHER: LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Efficacy and Safety of Ruxolitinib in Patients With COVID-19 Associated Cytokine Storm
Status: COMPLETED
Conditions: Cytokine Storm (Covid-19)
Interventions: DRUG: Ruxolitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring Outcomes In Patients With Pulmonary Arterial Hypertension Not on Active Treatment (MOTION)
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (Adempas, BAY63-2521)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Grains of Paradise (Aframomum Melegueta) on REE
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Grains of Paradise (Aframomum Melegueta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity, Safety, and Efficacy of Zarzio®/Filgrastim HEXAL® in Patients With Severe Chronic Neutropenia
Status: TERMINATED
Conditions: Severe Chronic Neutropenia
Interventions: BIOLOGICAL: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Lixivaptan in Subjects Previously Treated With Tolvaptan for Autosomal Dominant Polycystic Kidney Disease
Status: TERMINATED
Conditions: Polycystic Kidney Disease, Adult|ADPKD
Interventions: DRUG: Lixivaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Anxiety Management With Oral Narcotic for Pediatric Suture Repair
Status: COMPLETED
Conditions: Children|Lacerations|Procedures|Child|Pain
Interventions: DRUG: hydrocodone/acetaminophen|DRUG: Sugar water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK and Drug Interaction Study of Utidelone Plus Capecitabine in Patients With Advanced Breast Cancer
Status: COMPLETED
Conditions: Advanced and Metastatic Breast Cancer
Interventions: DRUG: Utidelone Injection; capecitabine|DRUG: Utidelone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Changes in Body Composition When Ingesting a Dairy Compound Enriched With Leucine
Status: COMPLETED
Conditions: Elderly Person|Body Composition|Physical Exercise
Interventions: DIETARY_SUPPLEMENT: dietary supplement consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy for 3 Months or 6 Months in Treating Patients With Stage III Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: CAPOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer
Status: TERMINATED
Conditions: Gastroesophageal Junction Adenocarcinoma|Stage IB Esophageal Adenocarcinoma AJCC v7|Stage II Esophageal Adenocarcinoma AJCC v7|Stage IIA Esophageal Adenocarcinoma AJCC v7|Stage IIB Esophageal Adenocarcinoma AJCC v7|Stage IIIA Esophageal Adenocarcinoma AJCC v7|Stage IIIB Esophageal Adenocarcinoma AJCC v7
Interventions: DRUG: Carboplatin|RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Taladegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating SGI-110 in Combination With Ipilimumab in Unresectable or Metastatic Melanoma Patients
Status: UNKNOWN
Conditions: Metastatic Melanoma
Interventions: DRUG: SGI-110|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet Intervention and GEnetic STudy (DIGEST-Pilot)
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Inflammation|Dyslipidemias|Blood Pressure|Hyperglycemia
Interventions: OTHER: Prudent Diet|OTHER: Typical Western Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AfyaJamii (Parenting Well): Evaluating the Feasibility of a Group Antenatal/Well-child Care Model in Pregnancy in Kenya
Status: COMPLETED
Conditions: Pregnancy Related|Group, Peer
Interventions: BEHAVIORAL: AfyaJamii
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre TAVI Membranous Septum Measurement Predicts High Grade Iatrioventricular Conduction Disorders in Patients With Specific Pacemaker Implanted After TAVI. The STIM TAVI-MS Study
Status: COMPLETED
Conditions: Conduction Disturbance|Trans Aortic Valve Implantation (TAVI)
Interventions: DIAGNOSTIC_TEST: Trans aortic valve implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Story-Centred Care Intervention Program in Older Persons Living in Long-term Care Facilities
Status: COMPLETED
Conditions: Depression
Interventions: OTHER: Story-centred care intervention program|OTHER: Health consultation control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Falls Risk Questionnaire in Older Adults With Cancer
Status: COMPLETED
Conditions: Cancer|Geriatric Assessment
Interventions: OTHER: Falls Risk Questionnaire|OTHER: Cancer and Aging Research Group Geriatric Assessment|OTHER: Falls Efficacy Scale-International (FES-1)|OTHER: Health Related Quality of Life using the Functional Assessment of Cancer Therapy - Gynecologic Oncology Group Neurotoxicity Scale (FACT GOG/NTX)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Anti-Angiogenesis Agent Axitinib in Patients With Stage III Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma|Malignant Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma
Interventions: PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|DRUG: Axitinib|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Decaffeinated Green Tea Polyphenol Intake on the Risk of Precocious Puberty Among Obese Girls
Status: UNKNOWN
Conditions: Pediatric Obesity|Puberty, Precocious
Interventions: DIETARY_SUPPLEMENT: Decaffeinated Green Tea Polyphenol|OTHER: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of DERMAGEN® vs Conventional Treatment to Treat Diabetic Neuropathic Foot Ulcer
Status: UNKNOWN
Conditions: Diabetes|Foot Ulcer
Interventions: OTHER: Dermagen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Microbiological Evaluation of Laser Assisted New Attachment Procedure (LANAP) Using Nd:Yag vs. Diode Laser in the Management Of Stage II Periodontitis
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: DEVICE: Laser Assisted New Attachment Procedure using ND:YAG laser|DEVICE: Laser Assisted New Attachment Procedure using diode laser|PROCEDURE: Scaling and Root Planing using ultrasonic and curettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: iSIPsmarter: A Pilot RCT to Evaluate a Web-based Behavioral Intervention to Reduce Sugary Beverages Among Black Adults
Status: RECRUITING
Conditions: Diet Habit|Sugar-Sweetened Beverages
Interventions: BEHAVIORAL: iSIPsmarter|BEHAVIORAL: Patient Education (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Changes of Swallowing Function and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Therapy and Neuromuscular Electrical Stimulation in Stroke Patients With Dysphagia
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: swallowing therapy|OTHER: IOPI therapy|OTHER: neuromuscular electrical stimulation (NMES) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19
Status: COMPLETED
Conditions: Healthy|Chronic Stable Illness
Interventions: DRUG: REGN10933+REGN10987|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME)
Status: TERMINATED
Conditions: Diabetic Macular Edema
Interventions: DRUG: KSI-301|DRUG: Aflibercept|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peanut Reactivity Reduced by Oral Tolerance in an Anti-IgE Clinical Trial
Status: COMPLETED
Conditions: Peanut Allergy|Food Allergy
Interventions: DRUG: Omalizumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adductor Canal Block in Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Analgesia
Interventions: DRUG: Bupivacaine plus Normal Saline|DRUG: Bupivacain and ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1b/2a, Open-label,Randomized, Safety, Tolerability, Dose Finding, PK/PD, and Preliminary Efficacy Study of SC Hanferon™ in Combination With Ribavirin in Treatment-naïve Subjects With Genotype 1 Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection|Genotype 1
Interventions: DRUG: recombinant variant of interferon-alpha 2b|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha Entrainment for Pain and Sleep (Extension)
Status: RECRUITING
Conditions: Pain, Chronic|Sleep Disturbance
Interventions: DEVICE: Audio or visual alpha (10Hz) stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease
Status: TERMINATED
Conditions: Gaucher Disease
Interventions: DRUG: AVR-RD-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
Status: UNKNOWN
Conditions: Chronic Disease|Obesity|Hypertension|Diabetes|Self Care|Medication Adherence
Interventions: BEHAVIORAL: Active and Healthy Brotherhood (AHB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Mindful Body Awareness With Medication Treatment for Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Mindful Awareness in Body-oriented Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: New Biomarkers in the Prediction of Chemotherapy-induced Cardiotoxicity.
Status: RECRUITING
Conditions: Cardiotoxicity|Chemotherapy Effect|Chemotherapy Induced Systolic Dysfunction
Interventions: DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Cardio MRI|DIAGNOSTIC_TEST: 24-hours monitoring of ECG|DIAGNOSTIC_TEST: 24 hours monitoring of BP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Mindfulness Based Stress Reduction (MBSR) Programme for Reducing the Stress Level of Nursing Student
Status: COMPLETED
Conditions: Stress|Emotion Regulation
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction|OTHER: continuing a routine life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Postoperative Concurrent Chemoradiotherapy With Docetaxel for High-Risk Squamous Cell Carcinoma of Head and Neck
Status: COMPLETED
Conditions: Head-and-neck Cancer|Squamous Cell Carcinoma
Interventions: DRUG: Docetaxel|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mode of Action Study of Omalizumab in Patients With Chronic Idiopathic Urticaria (CIU) Who Fail to Respond to Antihistamine Treatment
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: IGE025|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Disease|Iron-deficiency Anemia
Interventions: DRUG: IV Iron|DRUG: Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Busulfan|DRUG: Cladribine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Peripheral Blood Stem Cell Transplantation|OTHER: Pharmacological Study|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With AVD in the First-line Treatment for Patients With Advanced Classical Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma
Interventions: DRUG: Camrelizumab|DRUG: Epirubicin|DRUG: Vincristine|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Balance Training And Dynamic Neuromuscular Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Status: RECRUITING
Conditions: Ankle Inversion Sprain|Chronic Instability of Joint|Chronic Pain|Athlete Foot
Interventions: PROCEDURE: Dynamic Neuromuscular Stabilization Training (DNS)|PROCEDURE: Balance Training|PROCEDURE: Conventional Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the Safety and Efficacy of the R/R B-NHL Regimen With BTK Inhibitor+Anti-CD19 CAR-T Cells
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: regimen with BTK inhibitor +Anti-CD19 CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Antiviral Efficacy of Telbivudine in Hepatitis B Antigen Positive (HbeAg-positive) Compensated Chronic Hepatitis B (CHB)
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Blocks for Total Hip Arthroplasty
Status: COMPLETED
Conditions: THA
Interventions: DRUG: Marcaine 0.25 % Injectable Solution|DRUG: Marcaine 0.25 % Injectable Solution|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Levetiracetam in Japanese Pediatric Patients With Generalized Tonic-clonic Seizures
Status: COMPLETED
Conditions: Epilepsy|Generalized Tonic-clonic Seizures
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET/MRI in the Diagnosis of Chronic Pain
Status: RECRUITING
Conditions: Neuropathic Pain|Nociceptive Pain|Mixed Pain (Nociceptive and Neuropathic)|Spinal Pain|Radiculopathy|Myelopathy|Neurogenic Claudication
Interventions: DRUG: [18F]FTC-146
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using the VisuMax Femtosecond Laser System to Perform SMILE Optimized for Presbyopia by Modulation of Postoperative Spherical Aberration
Status: ENROLLING_BY_INVITATION
Conditions: Myopia|Myopic Astigmatism|Presbyopia
Interventions: PROCEDURE: HiSMILE treatment option
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of a Family Heart Health Educational Program (The FIT-Heart Study)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Family Passport to Heart Health Program|BEHAVIORAL: General Educational Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin's Effect on the Advantageous- and Disadvantageous-inequity
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Intranasal oxytocin|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Influenza Vaccination on Global Systemic Inflammatory Markers in Patients With Stable Coronary Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Inflammatory Response|Atherosclerosis
Interventions: BIOLOGICAL: Influenza Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Different Remineralizing Agents in Treatment of White Spot Lesions
Status: UNKNOWN
Conditions: Remineralization
Interventions: DRUG: Monomeric self - assembling peptide P11-4|DRUG: Tricalcium phosphate fluoride varnish, 5% F-|DRUG: fluoride varnish (5% sodium fluoride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy, Safety and Tolerability of HLX26 and Serplulimab in Patients With mCRC
Status: SUSPENDED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: HLX26|DRUG: HLX10
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensitivity to Intravenous Nicotine: Genetic Moderators
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: saline|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet
Status: TERMINATED
Conditions: Respiratory Insufficiency|Respiratory Distress Syndrome, Adult|Chronic Obstructive Pulmonary Disease|Pulmonary Edema
Interventions: DEVICE: Helmet|DEVICE: Full-face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial Comparing Efficacy and Safety After Intensification With Either Insulin Aspart Once Daily as add-on or Changing to Basal Bolus Treatment With Insulin Degludec and Insulin Aspart in Subjects With Type 2 Diabetes Previously Treated With Insulin Degludec/Insulin Aspart Twice Daily
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/insulin aspart|DRUG: insulin degludec|DRUG: insulin aspart|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of PI3 (Phosphatidylinositol-3)-Kinase Inhibitor Copanlisib With Gemcitabine or Cisplatin Plus Gemcitabine in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Gemcitabine|DRUG: BAY80-6946|DRUG: Cisplatin|DRUG: NaCl|DRUG: BAY80-6964 fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
Status: COMPLETED
Conditions: Antibiotic Resistant Strain
Interventions: BIOLOGICAL: Encapsulated fecal microbiota preparation|BIOLOGICAL: Encapsulated placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis
Status: COMPLETED
Conditions: Anterior Uveitis|Arthritis, Juvenile Idiopathic|Iritis|Immunosuppression
Interventions: DRUG: Daclizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: COMPLETED
Conditions: Biliary Tract Diseases|Pancreatic Diseases
Interventions: DRUG: alfentanil|DRUG: remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode Laser
Status: COMPLETED
Conditions: Periodontal Pocket
Interventions: DEVICE: medency diode laser|DRUG: spirazole forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infections
Status: RECRUITING
Conditions: Bacterial Infections
Interventions: DRUG: Omadacycline Injection [Nuzyra]|DRUG: Omadacycline Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inhaled Milrinone Use in Patients Receiving HeartMate II LVAD: A Pilot Study
Status: COMPLETED
Conditions: End Stage Heart Disease|Right Ventricular Dysfunction
Interventions: DRUG: Inhaled, nebulized, Milrinone|DRUG: inhaled nebulized milrinone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Link Between the Peripheral Mononuclear Cells' Capacity to Induce Insulin Resistance and Hyperinsulinemia
Status: COMPLETED
Conditions: Insulin Resistance|Hyperinsulinism|Immune System
Interventions: DIAGNOSTIC_TEST: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single-Dose Fed Bioequivalence Study of Nisoldipine Extended-Release Tablets (40 mg; Mylan) and Sular® Extended-Release Tablets (40 mg; First Horizon) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nisoldipine Extended-release Tablets, 40 mg|DRUG: Sular Tablets, 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Hospitalization or Out-treatment ManagEment of Patients With Pulmonary Embolism: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: OTHER: HESTIA|OTHER: sPESI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Behavior Therapy vs Exposure in Vivo in the Treatment of Panic Disorder With Agoraphobia
Status: TERMINATED
Conditions: Panic Disorder With Agoraphobia
Interventions: BEHAVIORAL: Cognitive behavior therapy|BEHAVIORAL: Exposure in-vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of WJ-derived Mesenchymal Stem Cells in Combination With Parathyroid Hormone for Vertebral Compression Fracture
Status: UNKNOWN
Conditions: Vertebral Compression Fracture|Osteoporotic Fractures
Interventions: DRUG: WJ-MSC|DRUG: Teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Anlotinib Combined With Docetaxel in Patients With Wild-type Advanced Non-squamous Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Hydrochloride plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Trifarotene Cream, 0.005% To AKLIEF ® (Trifarotene 0.005% Cream) In The Treatment Of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Trifarotene 0.005 % Topical Cream|DRUG: AKLIEF®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Metoclopramide for Gastric Visualization in Active Upper GI Bleeding
Status: RECRUITING
Conditions: Upper GI Bleeding
Interventions: DRUG: Metoclopramide Sulfone|DRUG: Normal Saline 10 mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Ib Trial for the Evaluation of SAR260301 in Monotherapy or in Combination With Vemurafenib in Patients With Various Advanced Cancer
Status: COMPLETED
Conditions: Neoplasm Malignant
Interventions: DRUG: SAR260301|DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on Autologous Platelet-rich Plasma (PRP) Treatment for Refractory Benign Airway Stenosis
Status: UNKNOWN
Conditions: Benign Airway Stenosis
Interventions: PROCEDURE: PRP|PROCEDURE: Conventional treatment for benign airway stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Physiotherapy Program in Obese and Non-obese Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Obesity
Interventions: BEHAVIORAL: standard physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Anlotinib Combined With Icotinib as the First-line Treatment in Patients With EGFR Mutation-positive NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Anlotinib Plus Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Effects of an Experimental Drug on Postmenopausal Osteoporosis (MK-0822-004)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Odanacatib|DRUG: Odanacatib|DRUG: Odanacatib|DRUG: Odanacatib|DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Calcium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ingesting Multiple Boluses of Collagen on Muscle & Skin Connective Protein Synthesis in Vivo in Humans
Status: NOT_YET_RECRUITING
Conditions: Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Collagen protein|BEHAVIORAL: Resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Removal of Doravirine by Hemodialysis in HIV-Infected Patients With End-stage Renal Disease (ESRD)
Status: COMPLETED
Conditions: HIV-infected Participants With ESRD Undergoing Routine Hemodialysis
Interventions: DRUG: Doravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Method of Calculating the Shortest Incision for Internal Fixation of Zygomatic Arch Fracture
Status: COMPLETED
Conditions: Zygomatic Fractures
Interventions: PROCEDURE: sideburns mini incision|PROCEDURE: coronal scalp incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Combined Laparoscopic and Hysteroscopic Repair of CS Niche
Status: RECRUITING
Conditions: Cesarean Scar Niche
Interventions: PROCEDURE: laparoscopic repair of cesarean scar niche|PROCEDURE: Combined hysteroscopic and laparoscopic repair of cesarean scar niche
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Cannabidiol, Meal Ingestion, and Liver Function
Status: COMPLETED
Conditions: Metabolism|Liver Function|Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Cannabidiol (CBD) powder formulation|DIETARY_SUPPLEMENT: Cannabidiol (CBD) Oil based tincture formulation|DIETARY_SUPPLEMENT: Cannabidiol (CBD) Gum Arabic, maltodextrin base formulation|DIETARY_SUPPLEMENT: Cannabidiol (CBD) Gum Arabic, sorbitol base formulation|DIETARY_SUPPLEMENT: Cannabidiol (CBD) Isolate in water formulation|DIETARY_SUPPLEMENT: CBD matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ESP Block for Laparoscopic Nephrectomy Surgeries
Status: TERMINATED
Conditions: Kidney Cancer|Post-surgical Pain
Interventions: DRUG: Ropivacaine injection|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neighborhood Park Youth Sports Program Fee Waiver and Intensive Family Outreach
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Activity
Interventions: BEHAVIORAL: Experimental: Fee Waiver|BEHAVIORAL: Fee Waiver Plus Intensive Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Melatonin on Insomnia Symptoms in Older Adults
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: Melatonin 0.4 mg|DRUG: Melatonin 4.0 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Shot With Dexmedetomidine Versus Continuous Ultrasound-guided Erector Spinae Plane Block for Postoperative Pain Control After Percutaneous Nephrolithotomy
Status: UNKNOWN
Conditions: Stone, Kidney
Interventions: DRUG: single shot ESBP with dexmedtomidine|DRUG: continous ESPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: En-mass Retraction by Lingual Retractor Versus Clear Aligner Appliances
Status: NOT_YET_RECRUITING
Conditions: Maxillary Prognathism
Interventions: DEVICE: Lingual Retractor Appliance|DEVICE: clear aligner
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-guided Acceptance and Commitment Therapy-based Digital Smartphone Application for Management of Fibromyalgia
Status: NOT_YET_RECRUITING
Conditions: Fibromyalgia
Interventions: DEVICE: Self-guided digital Acceptance and Commitment Therapy|DEVICE: FM symptom tracking app (FM-ST)|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEK Inhibitors for the Treatment of Hypertrophic Cardiomyopathy in Patients With RASopathies
Status: RECRUITING
Conditions: Cardiomegaly|Noonan Syndrome
Interventions: DRUG: Trametinib tablet|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SM04554 Applied Topically to the Scalp of Male Subjects With Androgenetic Alopecia Analyzed by Biopsy of the Scalp Prior To and Post Dosing
Status: COMPLETED
Conditions: Androgenetic Alopecia
Interventions: DRUG: Topical SM04554 solution|DRUG: Topical Vehicle solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Extension Study to Evaluate Continuous Safety and Efficacy of BIIB059 (Litifilimab) in Adults With Active Subacute Cutaneous Lupus Erythematosus (CLE) and/or Chronic CLE With or Without Systemic Manifestations and Refractory and/or Intolerant to Antimalarial Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Subacute Cutaneous Lupus Erythematosus|Chronic Cutaneous Lupus Erythematosus
Interventions: DRUG: BIIB059 (litifilimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapleural Urokinase for Retained Hemothorax
Status: UNKNOWN
Conditions: Retained Hemothorax
Interventions: DRUG: urokinase|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Follow Up of an Online Hearing Support for First-time Hearing Aid Users
Status: ENROLLING_BY_INVITATION
Conditions: Hearing Loss|Hearing Impairment|Hearing Disorders
Interventions: BEHAVIORAL: Swedish I-ACE|BEHAVIORAL: Clinical visit|OTHER: No follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Telehealth Technology in Asthma Management
Status: NOT_YET_RECRUITING
Conditions: Asthma Exacerbation|Quality of Life|Medication Adherence
Interventions: OTHER: CANATEXTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Lenvatinib and Pembrolizumab in Endocrine Resistant Breast Cancer With Letrozole
Status: RECRUITING
Conditions: Hormone Receptor-Positive HER2-Negative Advanced Breast Cancer
Interventions: DRUG: Oral lenvatinib + Intravenous (IV) pembrolizumab + Oral letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clınıcal Results of Evelator and Free Knot Methods In Medial Menıscus Posterior Root Tears
Status: COMPLETED
Conditions: Meniscus Tear|Meniscus Lesion
Interventions: PROCEDURE: ARTROSCOPİC SURGERY WITH ELEVATOR SYSTEM|PROCEDURE: ARTROSCOPİC SURGERY WITHOUT ELEVATOR SYSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Two Different Suprascapular Nerve Block Techniques in Patients With Chronic Shoulder Pain
Status: UNKNOWN
Conditions: Chronic Shoulder Pain
Interventions: PROCEDURE: US guided, SSNB with 1ml methylprednisolone acetate (1ml / 40mg) and 5 ml 0.5% bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting-stents for Unprotected Left Main Stem Disease (ISAR-LEFT-MAIN)
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Sirolimus-eluting stent|DEVICE: Paclitaxel-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph I/II Study of CAR19 Regulatory T Cells (CAR19-tTreg) for R/R CD19+ B-ALL
Status: WITHDRAWN
Conditions: Lymphoma Leukemia
Interventions: DRUG: allogeneic CAR19 regulatory T cells (CAR19-tTreg)|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy
Status: UNKNOWN
Conditions: Acid Reflux Esophagitis|Non-acid Reflux Esophagitis
Interventions: DRUG: Lanreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on Sensitive Symptoms of Distal Diabetic Peripheral Neuropathy
Status: RECRUITING
Conditions: Electroacupuncture|Acupuncture|Diabetic Polyneuropathy|Diabetic Peripheral Neuropathy|Diabetic Peripheral Neuropathic Pain|Nerve Conduction
Interventions: PROCEDURE: Electroacupuncture|PROCEDURE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Curative Image Guided Radiotherapy for Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: RADIATION: radiotherapy daily verification reduced safety margins|RADIATION: radiotherapy weekly verification standard safety margins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial Effect of Tropolone Containing Versus Tropolone Free Mouthwash
Status: RECRUITING
Conditions: Dental Diseases
Interventions: COMBINATION_PRODUCT: Listerine total care zero|COMBINATION_PRODUCT: Chlorhexidine Mouthwash (0.2%).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BREATHE-Peds Pilot- II III Trial and Post Trial
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: BREATHE-Peds Intervention|BEHAVIORAL: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: General Anesthesia and Regional Cerebral Oxygenation inSpine Surgery Prone Position
Status: COMPLETED
Conditions: Spinal Disease
Interventions: DRUG: Maintenance of general anesthesia by Sevoflurane|DRUG: Maintenance of general anesthesia by Desflurane|DRUG: Anesthesia was maintained by inhalational anesthesia (total intravenous anesthesia by lidocaine, propfol and fentanyl infusions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER