pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Relationship Between Postoperative Oxygenation and STOP-BANG Questionnaire and 4-V Tool
Status: COMPLETED
Conditions: Hypoxia|Bariatric Surgery
Interventions: PROCEDURE: hypoxia|PROCEDURE: normooxy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase IIb/III Study of Prof-001 for the Treatment of Patients With Recurrent Vulvovaginal Candidiasis (RVVC)
Status: UNKNOWN
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DRUG: Prof-001|DRUG: Fluconazole 150 mg|DRUG: Placebo cream|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Smartphone App on the Quality of Pediatric Colonoscopy Preparations
Status: COMPLETED
Conditions: Pediatric ALL
Interventions: DEVICE: Smartphone App "SB Colonoscopy Prep"|OTHER: Written Instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CBT-1® in Combination With Doxorubicin in Patients With Metastatic, Unresectable Sarcomas Who Previously Progressed on Doxorubicin
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: CBT-1®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Palatal Temporary Anchorage Device for Anterior Open Bite
Status: RECRUITING
Conditions: Anterior Openbite
Interventions: DEVICE: Single Palatal TAD|DEVICE: Two buccal TADs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eradication of H. Pylori Therapy Individualized by the Mutation of 23S rRNA of H. Pylori
Status: UNKNOWN
Conditions: H. Pylori Infection
Interventions: DRUG: Eradication of H. pylori
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Corticosteroid Injection Into Coracohumeral Ligament in Patients With Adhesive Capsulitis of the Shoulder
Status: UNKNOWN
Conditions: Direct Coracohumeral Ligament Steroid Injection
Interventions: PROCEDURE: Intraarticular triamcinolone injection|PROCEDURE: Intraarticular Xylocaine injection|PROCEDURE: Coracohumeral ligament triamcinolone injection|PROCEDURE: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Treatment of Stent Underexpansion Caused by Calcification Using Intravascular Lithotripsy
Status: NOT_YET_RECRUITING
Conditions: Intravascular Lithotripsy
Interventions: DEVICE: intravascular lithotripsy|DEVICE: high-pressure ballon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: HSK21542 Injection|DRUG: Tramadol hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erector Spina Muscle Distance From the Skin at Different Thoracal Elevations
Status: COMPLETED
Conditions: Pain, Postoperative|Pain, Back
Interventions: OTHER: Comparison of the distance of the Erector Spina muscle from the skin at different thoracal levels and different posıtıons under ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect Of Supportive Approach According To Kolcaba Comfort Theory Applied To Parents Of Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: theory-based education-consulting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: PCSK9 inhibitor in combination with standard advanced first-line regimen group|DRUG: standard advanced first-line regimen group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Sarcoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: estramustine phosphate sodium|DRUG: paclitaxel|DRUG: vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of SF1126, a PI3 Kinase (PI3K) Inhibitor, Given By Intravenous (IV) Infusion in Patients With Solid Tumors
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors|Cancer|Solid Cancers
Interventions: DRUG: SF1126
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence, Etiology and Therapy of Micturition Disorders of Children With a Mental and/or Motoric Disability
Status: COMPLETED
Conditions: Micturition Disorder
Interventions: PROCEDURE: Questionnaire and micturition and drinking diaries|PROCEDURE: Clinical and functional examination (uroflowmetry, bladder scan and video-urodynamic examination)|BEHAVIORAL: Adaptation of the drinking scheme|DRUG: Anticholinergic therapy|BEHAVIORAL: Micturition clock
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of Foot Reflexology Massage on Heart Rate Variability and Arterial Pulse Waveform
Status: COMPLETED
Conditions: Massage|Anaerobic Exercise|Aerobic Exercise
Interventions: OTHER: Foot reflexology massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Protocols of Optimization of X Ray Radiations in Pediatric Interventional Neuroradiology
Status: TERMINATED
Conditions: Occlusion or Malformation of a Cerebral Vessel
Interventions: DEVICE: protocol of optimization ALARA|DEVICE: protocol of optimization Philips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Kerr SonicFill™ 2 vs 3M ESPE Filtek™ Supreme Ultra Universal Restorative
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: SonicFill™ 2|DEVICE: Filtek™ Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib, Tamoxifen, and Cisplatin in Treating Patients With High-Risk Stage III Melanoma
Status: UNKNOWN
Conditions: Melanoma (Skin)
Interventions: DRUG: cisplatin|DRUG: sorafenib tosylate|DRUG: tamoxifen citrate|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Comprehension and Execution of Medication Prescriptions in Parkinsonian Patients and Healthy Volunteers
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: reading a table format prescription on a touch screen|OTHER: reading a textual format prescription on a touch screen|OTHER: filling a virtual pillbox displayed on the screen as prescribed in the prescription|OTHER: eye-tracker|OTHER: cognitive tests and questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Stepwise Labor Induction Following Failure of Prostaglandin Vaginal Insert for Labor Induction
Status: UNKNOWN
Conditions: Induction of Labor
Interventions: DRUG: Administration of Propess|DEVICE: balloon|DRUG: Intravenous oxytocin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Diesel Exhaust Particulate Exposures on Endothelial Function in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: N-acetylcysteine, ascorbate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Monitor Response to Treatment in Neuroblastoma Using 3&Apos;-Deoxy-3&Apos;-Fluorothymidine- Positron Emission Tomography (FLT-PET)
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DEVICE: FLT-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The NURLIFE Program for the Management of Bariatric Surgery Patients
Status: NOT_YET_RECRUITING
Conditions: Bariatric Surgery Candidate|Nurse-Patient Relations
Interventions: BEHAVIORAL: NURLIFE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Tocolytical Medications on Hemodynamics (Central and Peripheral) and Vascular Function in a Pilot Study to Determine the Design of the Final Study and the Final Study Itself
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ritodrine|DRUG: Atosiban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsule Versus Paclitaxel for Injection (Albumin Bound) in Subjects With Triple Negative Breast Cancer (TNBC)
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: TQB2450|DRUG: Anlotinib|DRUG: Paclitaxel for Injection (albumin bound)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors
Status: COMPLETED
Conditions: Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib|DRUG: pemetrexed disodium|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Effects of the Nutritional Supplement Sulforaphane on Doxorubicin-Associated Cardiac Dysfunction
Status: RECRUITING
Conditions: Anthracycline Related Cardiotoxicity in Breast Cancer
Interventions: DRUG: sulforaphane|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With HIV-Related Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|DRUG: didanosine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|DRUG: prednimustine|DRUG: zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prevalence of Replication of Human Herpes Virus 6 (HHV6) in Blood and Skin During Exanthemia, in Patients With Hemopathy. Is There a Correlation With the Etiology of the Exanthema?
Status: UNKNOWN
Conditions: HHV6|Exanthema|Hemopathy
Interventions: OTHER: Measurement of the prevalence of the positivity of cutaneous HHV6 quantitative PCR in the cohort studied.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Aricept (donepezil SR 23 mg)|DRUG: Aricept (donepezil IR 10 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Postmarket Surveillance Study of the Paradigm Spine Dynamic Stabilization System (DSS)
Status: TERMINATED
Conditions: Spondylolisthesis|Neurologic Deficits|Kyphosis|Pseudarthrosis
Interventions: DEVICE: Dynamic Stabilization System (DSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Tolerability and Effectivity of Two Combination Topical Acne Products
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Acnatac® Gel left face|DRUG: Epiduo® Gel right face|DRUG: Acnatac® Gel right face|DRUG: Epiduo® Gel left face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Epirubicin With Estramustine Phosphate and Celecoxib for the Treatment of Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Epirubicin|DRUG: Estramustine Phosphate|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Titanium Fusion Implant in Combination With Trans-iliac Screws for Insufficiency Fractures of the Pelvis
Status: RECRUITING
Conditions: Pelvic Fracture|Insufficiency Fractures|Mobility Limitation
Interventions: DEVICE: iFuse-3D implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Propofol and Fentanyl vs Propofol for Sedation in TRUS Biopsy
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Control|DRUG: Fentanyl|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effectiveness of Modified Toy Cars Training With Various Intensity of Postural Combinations
Status: COMPLETED
Conditions: Young Children With Motor Disabilities
Interventions: BEHAVIORAL: Ride-On Cars Training with Different Postures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Uterus for Uterine infertiLIty From Living Donor or Deceased Donor
Status: RECRUITING
Conditions: Uterine Factor Infertility
Interventions: PROCEDURE: Live donor uterus transplantation|PROCEDURE: Deceased donor uterus transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Thorough QT Study of Telotristat Etiprate
Status: COMPLETED
Conditions: QT Interval
Interventions: DRUG: Telotristat etiprate|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interim Digital PET/CT in Predicting Outcomes for Participants With Locally Advanced Oropharyngeal Cancer Undergoing Chemoradiation Therapy
Status: WITHDRAWN
Conditions: Oropharyngeal Squamous Cell Carcinoma|HPV Positive Oropharyngeal Squamous Cell Carcinoma
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients
Status: COMPLETED
Conditions: Left Ventricular Insufficiency
Interventions: DRUG: CD-NP|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
Status: NOT_YET_RECRUITING
Conditions: Hypertension|Diabetes|Postpartum|Pregnancy|Anxiety|Depression|Obesity
Interventions: OTHER: Facilitated Transition to Primary Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: EGEA4 THE 30 YEAR FOLLOW UP OF THE EGEA STUDY
Status: RECRUITING
Conditions: Healthy Volunteer EGEA4 Cohort
Interventions: OTHER: blood test, food collection, hair collection, calcium scan, etc.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of TENS Unit in the Management of Endometriosis Pain
Status: RECRUITING
Conditions: Endometriosis|Pelvic Pain
Interventions: DEVICE: Ovira Transcutaneous Electrical Nerve Stimulation Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementing an Evidence-based Exercise Program to Reduce Falls in Community-dwelling Older Adults (Otago)
Status: UNKNOWN
Conditions: Old Age; Debility|Fall
Interventions: BEHAVIORAL: Otago Exercise Programme+ (OEP+)|BEHAVIORAL: Otago Exercise Programme (OEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Rituximab|DRUG: Placebo|DRUG: Methylprednisolone|DRUG: Methotrexate|DRUG: Folic acid or folate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study.
Status: UNKNOWN
Conditions: Bone Neoplasm of Hip (Diagnosis)|Orthopedic Disorder|Bone Metastases|Proximal Femoral Metaphyseal Abnormality
Interventions: DIAGNOSTIC_TEST: CTFEA|OTHER: Conventional decision algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IPS Differentiated Cardiomyocytes Vein Transplantation for Chronic Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Chronic Heart Failure
Interventions: BIOLOGICAL: iPS differentiated cardiomyocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steady State Pharmacokinetics of Telmisartan, Ramipril or the Combination Following Repeated Oral Doses to Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D2C7-IT + 2141-V11 Combination Post-resection in rGBM
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma IDH Wildtype
Interventions: DRUG: D2C7-IT|DRUG: 2141 V11
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of L-dopa In Subacute Back Pain Population
Status: COMPLETED
Conditions: Sub-acute Back Pain
Interventions: DRUG: Naproxen|DRUG: Carbidopa/Levodopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retraining of the Amygdala and Insula for the Treatment of Persistent Covid
Status: RECRUITING
Conditions: Mental Health Wellness
Interventions: BEHAVIORAL: AIR + Mindfulness|BEHAVIORAL: Relaxation condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognition After Radiotherapy in CNS- and Skull-base Tumors
Status: RECRUITING
Conditions: Cognition|Brain Tumor|Magnetic Resonance Imaging|Meningioma|Glioma|Pituitary Adenoma
Interventions: BEHAVIORAL: Neurocognitive tests: WAIS digit span, HVLT-R, COWAT, MOCA, WAIS digit symbol substitution, TMT A&B, Stroop Color Word Test|DIAGNOSTIC_TEST: MRI|BEHAVIORAL: Questionnaires: EORTC QLQ C30 & BN20, STAI, CFQ, BDI-II, BRIEF-A, FACIT-F, PSQI|OTHER: Toxicity scoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of a Novel Ointment to Treat Plaque Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: AN2728|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized or Conventional Transfusion Strategies During Peripheral VA-ECMO
Status: RECRUITING
Conditions: Cardiogenic Shock|Extracorporeal Membrane Oxygenation|Transfusion Related Complication|Anemia|Oxygen Delivery
Interventions: DRUG: Packed Red Blood Cells (PRBCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Hypertonic Dextrose Water Injection for Supraspinatus Tendinosis Patients
Status: COMPLETED
Conditions: Chronic Shoulder Pain
Interventions: DEVICE: hypertonic dextrose water|DEVICE: Normal saline and Lidocaine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study for Latina Women After Breast Cancer Treatment
Status: COMPLETED
Conditions: Cancer-related Problem/Condition|Quality of Life|Stress, Emotional
Interventions: BEHAVIORAL: "My Guide" (psychoeducation & self-management program)|BEHAVIORAL: "My Health" (health education program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double Duty Interventions and Its Impact on Double Burden of Malnutrition in Children Under Five Years
Status: RECRUITING
Conditions: Malnutrition|Malnutrition, Child|Obesity|Undernutrition|Thinness
Interventions: BEHAVIORAL: double duty intervention packages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Docetaxel Combined With Cirmtuzumab in Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Cirmtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weather Sensitivity and the Effects of Walking in Nature on Stress Response of Individuals With Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Disease|Cardiac Rehabilitation|Nature, Human|Stress Reaction|Cognitive Function 1, Social
Interventions: OTHER: Walking outdoor|OTHER: Walking indoor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Clinical Efficacy of Moxibustion With Regulating Yin and Yang in the Treatment of Menopausal Obesity
Status: UNKNOWN
Conditions: Obesity
Interventions: DEVICE: Yin and Yang Regulating Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: cladribine|DRUG: cytarabine|DRUG: etoposide|DRUG: methotrexate|DRUG: mitoxantrone hydrochloride|DRUG: therapeutic hydrocortisone|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: low-LET cobalt-60 gamma ray therapy|RADIATION: low-LET electron therapy|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zarnestra and Gleevec in Chronic Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Chronic
Interventions: DRUG: Zarnestra (R115777)|DRUG: Gleevec (Imatinib mesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Care Physician: Integrated Inpatient and Outpatient Care for Patients at High Risk of Hospitalization
Status: ACTIVE_NOT_RECRUITING
Conditions: Medicare Patients|High Risk of Hospitalizations
Interventions: OTHER: Comprehensive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Anakinra Treatment for Patients With Post Acute Covid Syndrome
Status: RECRUITING
Conditions: Post-Acute COVID-19 Syndrome|Post-Acute COVID-19|Long COVID
Interventions: DRUG: Placebo|DRUG: Anakinra 149 MG/ML Prefilled Syringe [Kineret]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety and Tolerability of Lu AF20513 and the Antibody Response in Patients With Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Lu AF20513
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Hypertension
Interventions: DRUG: Placebo|DRUG: BI 10773|DRUG: Placebo|DRUG: BI 10773|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation (SCT) With Treosulfan, VP-16 and Cyclophosphamid for Patients With Acute Lymphoblastic Leukemia (ALL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: cisplatin|DRUG: cytarabine|DRUG: methylprednisolone|DRUG: pixantrone dimaleate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Efficacy of Intralesional Triamcinolone Versus Candida Albicans Antigen in Treating Alopecia Areata
Status: RECRUITING
Conditions: Alopecia Areata
Interventions: DRUG: Candida Albicans Antigen Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib for the Treatment of Refractory Chronic Graft-vs-Host Disease(cGVHD)
Status: UNKNOWN
Conditions: Chronic Graft-versus-host Disease
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tetracycline Pleurodesis on Prevention of Primary Spontaneous Pneumothorax Recurrence
Status: COMPLETED
Conditions: Primary Spontaneous Pneumothorax
Interventions: PROCEDURE: Chemical pleurodesis|DRUG: Tetracycline Topical Ointment|DRUG: Normal saline|DRUG: Lidocaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Study of Comprehensive Rehabilitation Program in Postoperative NSCLC Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: Rehabilitation Training|OTHER: Rehabilitation Education|DRUG: TCM|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1
Status: RECRUITING
Conditions: Unresectable Head and Neck Squamous Cell Carcinoma|Metastatic Head and Neck Cancer|Recurrent Head and Neck Cancer
Interventions: BIOLOGICAL: BNT113|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-assessment of Olfactory Disorders for French Speaking Patients
Status: COMPLETED
Conditions: Post-viral Anosmia|Post-traumatic Anosmia|Chronic Rhinosinusitis|Idiopathic Anosmia|Age-related Loss of Smell
Interventions: BEHAVIORAL: Self-assessment of olfactory disorders through two questionnaires.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Distribution of Rubidium-82, Nitrogen-13 Ammonia, and Fluorine-18 Fluorodeoxyglucose in Normal Volunteers
Status: COMPLETED
Conditions: Heart Disease
Interventions: OTHER: Rb-82 Pet scans|OTHER: F-18 FDG Pet scans|OTHER: N-13 ammonia Pet scans|DRUG: Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of Acquiring Hyperpolarized Imaging in Patients With Meningioma
Status: RECRUITING
Conditions: Meningioma
Interventions: DRUG: Hyperpolarized carbon C 13 pyruvate|PROCEDURE: Magnetic Resonance Image (MRI)|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study)
Status: COMPLETED
Conditions: Chronic Ischemic Heart Disease|Left Ventricular Dysfunction|Angina|Ischemic Cardiomyopathy
Interventions: BIOLOGICAL: Adult stem cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NOrthwestern Tempus AI-enaBLed Electrocardiography (NOTABLE) Trial
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Cardiovascular Diseases|Arrhythmia|Valvular Disease
Interventions: OTHER: TEMPUS AI-enabled ECG-based Screening Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Caffeine in Children With Obstructive Sleep Apnea, Dose Response Study
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Enlargement of Tonsil or Adenoid
Interventions: DRUG: Caffeine and sodium Benzoate 10 mg/kg IV|DRUG: Caffeine and Sodium Benzoate 20 mg/kg IV|DRUG: 0.9 NS Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating MyPath to Enhance Reproductive Autonomy and Liberate Decision-making
Status: TERMINATED
Conditions: Substance Use Disorders|Reproductive Issues|Contraception
Interventions: BEHAVIORAL: MyPath tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Loteprednol Ophthalmic Base Compared to Loteprednol Ophthalmic Suspension vs Placebo in an Allergen Challenge
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Loteprednol etabonate base (QD)|DRUG: Loteprednol etabonate base (BID)|DRUG: Loteprednol etabonate base (QID)|DRUG: Loteprednol etabonate suspension|DRUG: Vehicle of loteprednol etabonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Clinical Activity and Safety of JNJ-64041809, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Combination With Apalutamide Versus Apalutamide in Subjects With Metastatic Castration-resistant Prostate Cancer
Status: WITHDRAWN
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: JNJ-809|DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of MIND-BE Program on Mental Health Parameters (Mindfulness Based Empowerment)
Status: COMPLETED
Conditions: Resilience|Posttraumatic Growth|Mindfulness|Self-compassion|Mental Health
Interventions: OTHER: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Challenging Macular Holes Using Plasma Rich in Growth Factors
Status: RECRUITING
Conditions: Macular Holes
Interventions: BIOLOGICAL: Plasma rich in growth factors ( PRGF )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Voice Biomarkers Predictive of Depression and Anxiety
Status: COMPLETED
Conditions: Depression, Anxiety|Healthy|Mental Health Wellness 1
Interventions: DIAGNOSTIC_TEST: Patient Health Questionnaire-9|DIAGNOSTIC_TEST: Generalized Anxiety Disorder-7|DIAGNOSTIC_TEST: Hamilton Depression Rating Scale|DIAGNOSTIC_TEST: Hamilton Anxiety Rating Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Changes In Thermal Pain Response Following Single Oral Dose of Beta-Cary
Status: WITHDRAWN
Conditions: Beta-Caryophyllene
Interventions: DRUG: Low Dose Beta-Caryophyllene|DRUG: Medium Dose Beta-Caryophyllene|DRUG: High Dose Beta-Caryophyllene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Using fMRI to Determine if Cerebral Hemodynamic Responses to Pain Change Following Thoracic Spine Manipulation in Individuals With Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Thoracic spine manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Improving Anticoagulation Control in VISN 1
Status: COMPLETED
Conditions: Anticoagulants|Atrial Fibrillation|Venous Thromboembolism
Interventions: OTHER: Multifaceted behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Indacaterol in Adults (40 Years and Above) With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Indacaterol 150 µg|DRUG: Indacaterol 300 μg|DRUG: Placebo to indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Anaplastic Astrocytoma|Anaplastic Ependymoma|Anaplastic Oligodendroglioma|Gliosarcoma|Mixed Glioma|Recurrent Adult Brain Neoplasm|Recurrent Glioblastoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lapatinib|DRUG: Lapatinib Ditosylate|OTHER: Pharmacological Study|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enteric Nervous System in Alzheimer Disease
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: PROCEDURE: Rectosigmoidoscopy with colonic biopsies|PROCEDURE: Colonoscopy with colonic biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Khoury Technique Versus Titanium Reinforced PTFE Membrane in 3D Alveolar Bone Augmentation
Status: COMPLETED
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: Alveolar ridge augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genome Driven Primary Care Clinics - an RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Health Services Administration|Genetic Predisposition|Microbial Colonization
Interventions: GENETIC: Mutation arrays, NGS panels, GWAS, WES, WGS,|DEVICE: wearable monitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Chronic Pain|Opioid Use|Adductor Canal Block|Total Knee Arthroplasty
Interventions: DEVICE: ambIT pump with catheter|DEVICE: ambIT pump with sham catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda
Status: COMPLETED
Conditions: Hypertension; Community Health Workers
Interventions: BEHAVIORAL: Community health worker delivered multicomponent intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of Ocrelizumab in Adults With Primary Progressive Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Primary Progressive
Interventions: DRUG: Ocrelizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prognosis in Endometrial Cancer Treated With Different Surgical Methods: Laparoscopy, Robotic-assisted Laparoscopy and Laparotomy
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: PROCEDURE: Laparoscopic staging|PROCEDURE: Robotic staging|PROCEDURE: Laparotomic staging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Regulation of Intestinal Flora by Compound Probiotics in Patients With Chronic Hepatitis B
Status: NOT_YET_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Select the Dose and Evaluate Safety and Efficacy of Monoclonal Antibody in Adult With Recently Diagnosed Asymptomatic to Moderately Severe COVID-19.
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: MAD0004J08|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of AJ1-11095 in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) Who Have Been Failed by a Type I JAK2 Inhibitor (JAK2i)
Status: NOT_YET_RECRUITING
Conditions: Primary Myelofibrosis|Post-Essential Thrombocythemia Myelofibrosis|Post-Polycythemia Vera Myelofibrosis|PMF|PPV-MF|PET-MF
Interventions: DRUG: AJ1-11095
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIIb Study to Evaluate the Efficacy of Umeclidinium/Vilanterol (UMEC/VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UMEC/VI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids in Bipolar Affective Disorder
Status: WITHDRAWN
Conditions: Bipolar Affective Disorder
Interventions: DRUG: Synthetic cannabinoids (1:1 ratio of THC % CBD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: GSK3901961|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study for Ondansetron Hydrochloride Tablets 8 mg Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ondansetron Hydrochloride|DRUG: Ondansetron Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Proprioceptive Focal Stimulation (EQUISTASI) on Gait Parameters in Parkinson. Italian Multicentric Study
Status: COMPLETED
Conditions: Parkinson Disease|Gait, Shuffling|Effects of Vibration
Interventions: DEVICE: Equistasi|DEVICE: Inactive Equistasi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stepwise Positive End Expiratory Pressure Elevation For Lung Recruitment in Acute Respiratory Distress Syndrome (ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: Recruitment maneuver|PROCEDURE: recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VNP40101M in Treating Patients With Richter Syndrome or Refractory or Relapsed Chronic Lymphocytic Leukemia or Other Lymphoproliferative Disorders
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: laromustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer|Prostatic Neoplasms|Castrate-resistant Prostate Cancer (CRPC)|Androgen-insensitive Prostate Cancer|Hormone-refractory Prostate Cancer|Metastatic Disease
Interventions: DRUG: Temsirolimus|DRUG: Casodex (bicalutamide)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RE-MODEL Dabigatran Etexilate 150mg or 220mg Once Daily (o.d.) Versus (v.s.) Enoxaparin 40mg o.d. for Prevention of Thrombosis After Knee Surgery
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Thromboembolism
Interventions: DRUG: enoxaparin|DRUG: dabigatran etexilate|DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Application of Emotion Release Technology in Anxiety Patients Before Daytime Thyroid Surgery
Status: COMPLETED
Conditions: Anxiety|Day Surgery|Preoperative Nursing Care|Emotional Freedom Technique
Interventions: OTHER: emotional freedom technique (EFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Rapid Microscopic Diagnostic System for Different Vaginitis Conditions
Status: RECRUITING
Conditions: Bacterial Vaginosis|Candida Albicans Vulvovaginitis|Candida Vulvovaginitis|Trichomonas Vaginitis|Atrophic Vaginitis|Desquamative Inflammatory Vaginitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Boosting Refugee Integration Through Psychological Intervention: a Pilot Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Psychological Distress|PTSD|Trauma, Psychological
Interventions: BEHAVIORAL: Problem Management Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autonomic and Hemodynamic Responses to Inspiratory Muscle Exercise in Pre Hypertensive and Hypertensive Individuals
Status: COMPLETED
Conditions: Prehypertension|Hypertension
Interventions: OTHER: IME|OTHER: Sham IME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT