pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cisplatin/Vinorelbine/Bevacizumab Followed by Docetaxel/Gemcitabine/Bevacizumab Versus the Cisplatin/Docetaxel/Bevacizumab Combination in Locally Advanced or Metastatic NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Vinorelbine|DRUG: Cisplatin|DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Bevacizumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amitriptyline or Pregabalin to Treat Neuropathic Pain in Incurable Cancer
Status: UNKNOWN
Conditions: Cancer|Neuralgia
Interventions: DRUG: amitriptyline|DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Semaglutide 2.4 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Functional Dyspepsia
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DEVICE: taVNS|DEVICE: tnVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis
Status: RECRUITING
Conditions: Relapsing-remitting Multiple Sclerosis (RRMS)
Interventions: DRUG: CLS12311 low|DRUG: CLS12311 medium|DRUG: CLS12311 high|DRUG: uncoupled RBCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Generality of Laboratory-based Findings and Their Moderators in the ITC Study
Status: RECRUITING
Conditions: Cigarette Smoking|Nicotine Vaping
Interventions: OTHER: All nicotine/ tobacco products at market price|OTHER: Nicotine vaping products at 1/2 market price|OTHER: Heated tobacco products at 1/2 market price.|OTHER: Nicotine pouch products at 1/2 market price.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oncological and Functional Outcomes of Laparoscopic Partial Nephrectomy in Renal Cell Carcinoma Stages T1 Versus T2a: Prospective Comparative Study.
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: PROCEDURE: laparoscopic partial nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEMI Treated With Primary Angioplasty and Intravenous Lovenox or Unfractionated Heparin (UFH)
Status: COMPLETED
Conditions: Primary PCI - STEMI
Interventions: DRUG: Enoxaparin|DRUG: UFH (unfractionated heparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Status and Bouillon Use in Northern Ghana
Status: COMPLETED
Conditions: Iron Deficiency|Vitamin A Deficiency|Vitamin B 12 Deficiency|Folate Deficiency|Zinc Deficiency|Dietary Habits|Anemia
Interventions: OTHER: N/A (observational study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hyperbaric Radiation Sensitization of Head and Neck Cancers
Status: NOT_YET_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Hyperbaric oxygen|DEVICE: Hyperbaric chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DRUG: MBG453
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Term Efficacy and Mechanisms of Change of a Worry Postponement Intervention for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Worry Postponement|BEHAVIORAL: Worry Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy and Safety of Tenofovir Used Alone or in Combination With Pegylated Interferon Alpha-2b in Participants With Chronic Hepatitis B and Elevated Alanine Aminotransferase (MK-4031-384)
Status: WITHDRAWN
Conditions: Hepatitis B
Interventions: DRUG: Tenofovir|BIOLOGICAL: Pegylated interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of FLT-PET and DWI-MRI in Patients With NSCLC Treated With a Platinum-based Doublet as Preoperative Chemo
Status: UNKNOWN
Conditions: Non-small Cell Lung Carcinoma
Interventions: OTHER: 18F-FLT-PET/CT and DWI-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Alpha, gamma, beta, and delta (mixed) tocopherols|DRUG: alpha lipoic acid|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Readiness for Basic Life Support in Schools
Status: UNKNOWN
Conditions: Health Education|First Aid|Cardiopulmonary Resuscitation
Interventions: BEHAVIORAL: Protocol UN Lifeguard Kids in the Tunja version|BEHAVIORAL: Educational session accident prevention and wound management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Olaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated Tumors
Status: RECRUITING
Conditions: BRCA1 Mutation|BRCA2 Mutation|BRCA Mutation|PALB2 Gene Mutation|Checkpoint Kinase 2 Gene Mutation|ATM Gene Mutation
Interventions: DRUG: Olaparib|DRUG: ASTX727
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study
Status: TERMINATED
Conditions: Breast Neoplasm Female|Lymphoma|Cardiotoxicity|Anthracyclines|Physical Activity
Interventions: OTHER: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Yangxin Shengmai Granules for the Treatment of Stable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Heart Disease|Stable Angina
Interventions: DRUG: Yangxin Shengmai|DRUG: Yangxin Shengmai placebo|DRUG: nitroglycerin tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: BIOLOGICAL: Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|RADIATION: External Beam Radiation Therapy|PROCEDURE: Leukapheresis|PROCEDURE: Lymphodepletion Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops
Status: COMPLETED
Conditions: Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers|Choroidal Neovascularization
Interventions: DRUG: SYL18001 sodium Low dose q.d|DRUG: SYL18001 sodium Middle dose q.d|DRUG: SYL18001 sodium High dose q.d|DRUG: SYL18001 sodium High dose b.i.d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemiplegic Shoulder Pain Management Using Shoulder pRF and Corticosteroid Injection
Status: UNKNOWN
Conditions: Stroke|Shoulder Pain
Interventions: DRUG: Methylprednisolon, Lidocaine|OTHER: Pulsed radiofrequency, Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Tracer (68Ga-DOTATATE and 18F-FDG) PET Imaging in G2 & G3 Gastroenteropancreatic Neuroendocrine Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: F18-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Endovenous Microwave Ablation for Treatment of Varicose Veins
Status: RECRUITING
Conditions: Vascular Diseases, Peripheral|Venous Insufficiency of Leg|Varicose Veins of Lower Limb
Interventions: PROCEDURE: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients With Painful Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: placebo|DRUG: GZ389988|DRUG: acetaminophen or paracetamol|DRUG: fixed combination of paracetamol + codeine|DRUG: fixed combination of paracetamol + tramadol hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Music Therapy on Level of Consciousness
Status: RECRUITING
Conditions: Neurologic Disorder|Traumatic Brain Injury|Disorder of Consciousness
Interventions: BEHAVIORAL: Music Stimulation|BEHAVIORAL: Alternative Stimulation|BEHAVIORAL: No Auditory Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion Stents
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension, Portal|Ascites
Interventions: DEVICE: Gore® Viatorr® Endoprosthesis with controlled expansion|PROCEDURE: Large Volume Paracentesis with albumin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Maternal Arterial Hypotension After Spinal Anesthesia by Passive Leg Raise Test.
Status: RECRUITING
Conditions: Cesarean|Spinal Anesthesia
Interventions: OTHER: Clinical hemodynamic and echocardiographic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Economic Approaches to Increase Colorectal Cancer Screening
Status: COMPLETED
Conditions: Cancer of the Colon
Interventions: BEHAVIORAL: Email outreach|BEHAVIORAL: Active choice|BEHAVIORAL: Financial incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of a Once Daily Dose of Atomoxetine (ATX) on ADHD-Related Insomnia in Children and Adolescents
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Insomnia
Interventions: DRUG: atomoxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dynamic Cupping Versus Myofascial Release Therapy in Patients With Mechanical Neck Pain
Status: RECRUITING
Conditions: Mechanical Neck Pain
Interventions: PROCEDURE: dry cupping massage|PROCEDURE: Myofacial release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct-Current Stimulation in Childhood Dystonia
Status: UNKNOWN
Conditions: Childhood Onset Dystonias
Interventions: DEVICE: TDCS (Transcranial Direct-current Stimulation)|DEVICE: sham TDCS (Transcranial Direct-current Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resection of Pulmonary Metastasis in Clear Cell Renal Cell Carcinoma +/-Adjuvant Sunitinib Therapy (SMAT)
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Pulmonary Metastases
Interventions: DRUG: Sunitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Plantar Sensitivity Training and Aerobic Exercise Training in Patients With Multiple Sclerosis (PlaSTAcET Study)
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: plantar sensitivity training|OTHER: aerobic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Trial of Single Subcutaneous Doses of NNC 0113-0217 to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab in Participants With Familial Adenomatous Polyposis
Status: COMPLETED
Conditions: Adenomatous Polyposis Coli
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Modulation as Antidepressant Randomized Trial
Status: COMPLETED
Conditions: Depression|Healthy
Interventions: DEVICE: Phase-targeted auditory stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Feasibility of MR-Guided High Intensity Focused Ultrasound (MR-HIFU) Ablation of Osteoid Osteoma in Children
Status: COMPLETED
Conditions: Osteoid Osteoma
Interventions: DEVICE: MR-HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Milled Resin Composite in Restoration of Endodontically Treated Posterior Teeth Over One Year
Status: COMPLETED
Conditions: Endodontically Treated Teeth
Interventions: OTHER: Reinforced composite for the fabrication of permanent, indirect restorations using a CAD/CAM grinding process.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in the Treatment of Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: Raw, lacto-fermented sauerkraut|DIETARY_SUPPLEMENT: Mutaflor|OTHER: Pasteurized sauerkraut|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the HeartHab Application on Exercise Capacity in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Use of HeartHab application followed by usual care|OTHER: Usual care followed by the use of HeartHab application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fractional Flow Reserve or 3D-Quantitative-Coronary-Angiography Based Vessel-FFR Guided Revascularization
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: vFFR guided revascularization|DEVICE: FFR guided revascularization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin Traction Versus Position Splint in Patients With Hip Fracture
Status: COMPLETED
Conditions: Hip Fractures|Complication of Traction Procedure|Pain|Splints
Interventions: DEVICE: Derotation splint|DEVICE: elastic bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NATURE (EnVast as an Adjunct PPCI in Subjects Presenting With STEMI)
Status: RECRUITING
Conditions: Segment Elevation Myocardial Infarction (STEMI)
Interventions: DEVICE: enVast stent|PROCEDURE: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Tolerability of Exogenous Ketosis Induced by Free Beta-hydroxybutyrate.
Status: UNKNOWN
Conditions: Exogenous Ketosis
Interventions: DIETARY_SUPPLEMENT: Free Beta-hydroxybutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Effects of 90 mg Intravenous Infusions of GC4419 on the Single Dose Pharmacokinetics of Dextromethorphan in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dextromethorphan HBr|DRUG: GC4419
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Noninvasive Ventilation On Functional Capacity Of Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Noninvasive Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Safety and Effectiveness of Lutetium-177 Octreotate Therapy in Neuroendocrine Tumours
Status: RECRUITING
Conditions: Carcinoma, Neuroendocrine
Interventions: DRUG: [177]Lu-DOTA-TATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain
Status: COMPLETED
Conditions: Acute Pain|Bunion|Abdominoplasty
Interventions: DRUG: Wafermine™ 50 mg|DRUG: Wafermine™ 75 mg|DRUG: Placebos|DRUG: Wafermine™ 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Visceral Adiposity in HIV Mono-infected Patients With NAFLD
Status: UNKNOWN
Conditions: Visceral Steatosis|Hiv|NAFLD
Interventions: DEVICE: Bone densitometry|OTHER: Questionnaires|DEVICE: Review of medical chart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Comparing Halobetasol Propionate and Tazarotene Topical Lotion 0.01%/0.045% to Duobrii® Lotion (Halobetasol Propionate and Tazarotene Lotion), 0.01%/0.045% (Reference Listed Drug) in the Treatment of Moderate to Severe Plaque Psoriasis.
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Halobetasol Propionate and Tazarotene Lotion 0.01%/0.045%|DRUG: Duobrii® Lotion (Halobetasol propionate and tazarotene lotion), 0.01%/0.045%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HR Versus RFA for HCC in Patients With PHT
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular|Liver Neoplasms|Neoplasms, Glandular and Epithelial
Interventions: PROCEDURE: Hepatic Resection|PROCEDURE: Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTM202 for the Treatment of Environmental Enteric Dysfunction (EED)
Status: COMPLETED
Conditions: Environmental Enteric Dysfunction
Interventions: DIETARY_SUPPLEMENT: PTM202|DIETARY_SUPPLEMENT: micro-nutrient sprinkles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Reactogenicity of PCV13 Among Infants and Children in Burkina Faso
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Prevnar13 (manufactured by Pfizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Disorder, Major|Obesity
Interventions: DRUG: Simvastatin 40mg|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Dose-Response Study of Rivoglitazone in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Rivoglitazone HCl|DRUG: rivoglitazone HCl|DRUG: rivoglitazone HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incision and Loop Drainage Utilizing a Novel Technique for Management of Cutaneous Abscess in an Adult Population
Status: WITHDRAWN
Conditions: Abscess|Drain Abscess
Interventions: PROCEDURE: incision and loop drainage|DEVICE: traditional incision and drainage (I&D)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Randomized, Double-blind, Double-dummy Clinical Study to Evaluate the Safety and Efficacy of Prulifloxacin Film-coated Tablet for the Treatment of Acute Exacerbations of Chronic Bronchitis With Levofloxacin Hydrochloride Tablet as Active Control
Status: UNKNOWN
Conditions: Acute Exacerbations of Chronic Bronchitis
Interventions: DRUG: Prulifloxacin|DRUG: Levofloxacin|DRUG: Levofloxacin Placebo|DRUG: Prulifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women
Status: COMPLETED
Conditions: Alcohol; Harmful Use|Binge Drinking|Risk Behavior|HIV Infection
Interventions: BEHAVIORAL: Computerized brief alcohol intervention + IVR booster calls|BEHAVIORAL: Computerized brief alcohol intervention|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Efficacy of Topical Medications Containing Benzoyl Peroxide and Sulfur in the Regression in the Short Time (24 Hours) of Moderate Acne Vulgaris Grade II (Pimples)
Status: UNKNOWN
Conditions: Treatment of Acne Vulgaris Grade II in a Short Period of Time.
Interventions: DRUG: Benzoyl peroxide and sulfur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PReSeRVE-HD: Observational Study of the Merit HeRO® Graft and Super HeRO® in Patients on Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease|Hemodialysis Access Failure
Interventions: DEVICE: HeRO® Graft System or Super HeRO® System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Acute Effect of Novel Olive Oil on Postprandial Oxidative Stress Biomarkers (BioliveCT)
Status: COMPLETED
Conditions: Cardiometabolic Risk
Interventions: OTHER: Functional olive oil, enhanced with orange peel extract|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Hippotherapy Simulators on Trunk Control and Upper Extremity Functions in Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Hippotherapy group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: DRUG: empagliflozin|DRUG: metformin|DRUG: sulfonylurea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REgulatory T Cell infuSion fOr Lung Injury Due to COVID-19 PnEumonia
Status: COMPLETED
Conditions: COVID19|ARDS
Interventions: BIOLOGICAL: CK0802|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Laryngeal Injury|Hoarseness|Cough|Sore-throat|Intubation Complication|Bucking, Anesthesia Related
Interventions: DEVICE: Triglotix®|DEVICE: Conventional endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy
Status: RECRUITING
Conditions: Biliary Tract Cancer|DNA Damage Repair Deficiency
Interventions: DRUG: Durvalumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstetrical Analgesia in the Estaing Hospital Maternity. A Prospective Database to Study the Determinants of Labor Pain and the Resulting Maternal Non Satisfaction.
Status: UNKNOWN
Conditions: Epidural Analgesia|Hospital Follow-up
Interventions: OTHER: analgesia for labor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: DS-2330b PIB|DRUG: Placebo|DRUG: Sevelamer|DRUG: DS-2330b Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ALK21-003EXT: An Extension of Study ALK21-003 (NCT01218958) to Test the Long-term Safety of Medisorb® Naltrexone (VIVITROL®)
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Medisorb naltrexone 190 mg|DRUG: Medisorb naltrexone 380 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib Plus Fulvestrant With Pyrotinib in Hormone Receptor-positive, HER2-low Advanced Breast Cancer That Progressed on Previous CDK4/6i Plus AI Therapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Pyrotinib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Potential Effect of Innovative Treatment by Adjuvant Injection of Stromal Vascular Fraction From Autologous Adipose Tissue of URethral Stenosis With Endoscopic Urethrotomy
Status: RECRUITING
Conditions: Urethral Stenosis
Interventions: PROCEDURE: lipoaspiration|PROCEDURE: urethrotomy|DRUG: autologous ADSVF administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Lens Design on Particulate Exchange in the Post-lens Tear Film
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: etafilcon a Test 1|DEVICE: etafilcon A Test 2|DEVICE: etafilcon A Test 3|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy
Status: WITHDRAWN
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: avelumab|BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: 5Fluorouracil (5-FU)|DRUG: fulvestrant|DRUG: leucovorin|DRUG: nab-paclitaxel|DRUG: Lovaza|RADIATION: Stereotactic Body Radiation Therapy|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: ETBX-021|BIOLOGICAL: ETBX-051|BIOLOGICAL: ETBX-061|BIOLOGICAL: GI-4000|BIOLOGICAL: GI-6207|BIOLOGICAL: GI-6301|BIOLOGICAL: haNK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric|Pediatric Cancer
Interventions: BEHAVIORAL: Active Music Engagement|BEHAVIORAL: Audio Storybooks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: desferal|DRUG: Isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga-Pilates Exercise & the Effects on Urethral Rhabdosphincter Morphology and Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: BEHAVIORAL: Yoga-Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ObsErvational Study of the Practical Cinical UTility of the NuQ.® H3.1 Nucleosome Levels in Adult Patients With Sepsis to Facilitate Early Diagnosis and Prognostication. (EPICETUS)
Status: RECRUITING
Conditions: Sepsis
Interventions: DIAGNOSTIC_TEST: NuQ H3.1 Nucleosome Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides
Status: WITHDRAWN
Conditions: Hypertriglyceridemia
Interventions: DRUG: 290 mg DCCR|DRUG: 435 mg DCCR|DRUG: 135 mg fenofibric acid|DRUG: Placebo|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADAPT for Adolescents Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: SOC-REC/SOC-OIC|BEHAVIORAL: SOC-REC/CCT|BEHAVIORAL: SOC-REC/IP-NAV|BEHAVIORAL: E-NAV/SOC-OIC|BEHAVIORAL: E-NAV/CCT|BEHAVIORAL: E-Nav/IP-NAV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Balloon Lithoplasty for Preparation of Severely Calcified Coronary Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Percutaneous Coronary Intervention|Coronary Artery Calcification|Coronary Artery Disease
Interventions: DEVICE: Lithoplasty|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Lutein Supplementation on Macular Pigment Optical Density and Visual Acuity in Patients With Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: lutamax (leutein)|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ACY-1215 + Nab-paclitaxel in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Breast Carcinoma
Interventions: DRUG: ACY-1215|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Related Memory Consolidation in Children With Age Related Focal Epilepsy.
Status: RECRUITING
Conditions: Benign Epilepsy With Centro Temporal Spikes (BECTS)|Atypical Benign Partial Epilepsy (ABPE)|Epileptic Encephalopathy With Continuous Spike and Waves During Sleep (ECSWS)
Interventions: BEHAVIORAL: Neuropsychological testing|BEHAVIORAL: Neuropsychological procedure|OTHER: Video EEG and polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Postbiotics Supplementation on Exercise-induced Oxidative Stress.
Status: RECRUITING
Conditions: Postbiotics Supplement
Interventions: DIETARY_SUPPLEMENT: Postbiotics supplementation|DIETARY_SUPPLEMENT: Placebo supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effect of Standardized Exercise on Cardiopulmonary Function in Patients With Permanent Pacemaker Implantation
Status: COMPLETED
Conditions: Pacemaker DDD|Cardiopulmonary Endurance
Interventions: OTHER: Supervise and guide regular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phototherapy and Cryotherapy in Post-exercise Skeletal Muscle Recovery
Status: COMPLETED
Conditions: Post-exercise Muscle Recovery
Interventions: OTHER: PBMT|OTHER: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Tight Glycaemic Control in Acute Myocardial Infarction
Status: TERMINATED
Conditions: Myocardial Infarct|Hyperglycemia
Interventions: DRUG: Insulin (tight blood glucose control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Low-Grade Astrocytoma
Status: TERMINATED
Conditions: Low-Grade Astrocytoma, Nos
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Folfox4 Only Versus Folfox4 Plus Transhepatic Arterial Chemotherapy (TAC) in the Treatment Unresectable Liver Metastasis of Colorectal Cancer
Status: COMPLETED
Conditions: Unresectable Liver Metastasis of Colorectal Cancer
Interventions: PROCEDURE: tac + folfox4|PROCEDURE: Folfox4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics to Prevent Relapse After Hospitalization for Mania
Status: COMPLETED
Conditions: Bipolar Disorder|Schizoaffective Disorder
Interventions: DIETARY_SUPPLEMENT: Probiotic Supplement|DIETARY_SUPPLEMENT: Inert Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa
Status: COMPLETED
Conditions: Acute Otitis Externa
Interventions: DRUG: Ciprodex®|DRUG: EXL CDOS (Ciprofloxacin 0.3% and Dexamethasone 0.1%) Sterile Otic Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Training and Clinical Status in Patients With Post Discharge Symptoms After Covid-19
Status: COMPLETED
Conditions: Covid19|SARS-CoV2|Fatigue Syndrome, Chronic|Stress, Psychological|Pain, Chronic
Interventions: BEHAVIORAL: Resistance training|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single-center Clinical Study on the Safety and Effect of Bronchoscopic Cryotherapy in Patients With Chronic Cough
Status: RECRUITING
Conditions: Chronic Cough
Interventions: PROCEDURE: General treatment|PROCEDURE: Cryotherapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1
Status: COMPLETED
Conditions: Neurofibromatosis 1|Cutaneous Neurofibroma
Interventions: DRUG: Diclofenac Sodium|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous CD34+ Hematopoietic Stem Cells Transduced ex Vivo With Elongation Factor 1 Alpha Shortened (EFS) Lentiviral Vector Encoding for the Human ADA Gene
Status: COMPLETED
Conditions: ADA-SCID
Interventions: GENETIC: Infusion of autologous EFS-ADA LV CD34+ (OTL-101)|DRUG: busulfan|DRUG: PEG-ADA ERT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-individual Comparison of Efficacy and Safety of Metvix® Natural Daylight Photodynamic Therapy Versus Conventional Metvix® Photodynamic Therapy in Subject With Mild Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Metvix and natural daylight PDT|DRUG: Metvix and conventional PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Occlusafe® Assisted MW Alone or With DEB-TACE Compared to MW With DEB-TACE in the Treatment of HCC
Status: RECRUITING
Conditions: HCC
Interventions: PROCEDURE: Microwave ablation + Occlusafe + DEB-TACE|PROCEDURE: Microwave ablation + Occlusafe|PROCEDURE: Microwave ablation + DEB-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Preimplantation Portal Vein and Hepatic Artery Flushing With Tacrolimus
Status: COMPLETED
Conditions: Early Allograft Dysfunction|Ischemic Reperfusion Injury|Liver Transplantation|Hyperfibrinolysis
Interventions: DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Chronic Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
Status: RECRUITING
Conditions: Oropharyngeal Dysphagia|Stroke|Stroke, Complication|Swallowing Disorder
Interventions: DEVICE: rTMS + capsaicin 150μM (natural TRPV1 agonist)|DEVICE: tDCS + capsaicin 150μM (natural TRPV1 agonist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAINBOW Study: RAnibizumab Compared With Laser Therapy for the Treatment of INfants BOrn Prematurely With Retinopathy of Prematurity
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Ranibizumab|PROCEDURE: Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Acupuncture on Pain Related to the Screening of Premature Retinopathy (ROP) by Digital Camera
Status: COMPLETED
Conditions: Laser Stimulation
Interventions: DEVICE: Laser stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Effect of Telmisartan (Micardis® 80 mg/ MicardisPlus® 80/12.5 mg) on Blood Pressure and Cardiovascular Risk Factor Index in High Risk Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Progesterone and Doppler in Recurrent Abortion
Status: UNKNOWN
Conditions: Abortion in First Trimester
Interventions: DRUG: Progesterone Suppositories Vaginal|DRUG: Dydrogesterone Oral Tablet|DEVICE: doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of MRI With PET / CT in the Evaluation of Response to Neoadjuvant Therapy Based on the Molecular Subtypes of Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy Effect
Interventions: DRUG: Chemotherapy|DIAGNOSTIC_TEST: Magnetic Resonance Imaging (MRI)|DIAGNOSTIC_TEST: Positron emission tomography - Copmputer Tomography (PET-CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Effect of Fingolimod on Circulating Immunocompetent Mononuclear Cells in Patients With Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunonutrition Supplementation for Improved Burn Wound Healing in Older Adults
Status: ENROLLING_BY_INVITATION
Conditions: Burn Wound
Interventions: DIETARY_SUPPLEMENT: Impact Advanced Recovery|DIETARY_SUPPLEMENT: Boost High Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Lorlatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients
Status: RECRUITING
Conditions: Leukemia, Acute|Myelodysplastic Syndromes|Myelomonocytic Leukemia, Chronic|T-cell Prolymphocytic Leukemia|CML|Myeloproliferative Disorders|Multiple Myeloma|Plasma Cell Leukemia
Interventions: DRUG: Itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids and Nutritional Support in Gastrointestinal Cancer
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: omega-3|DIETARY_SUPPLEMENT: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Safety, Tolerability, and Efficacy of CordSTEM-DD in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain|Disc Degeneration
Interventions: BIOLOGICAL: CordSTEM-DD (0.7 x 10^7 cells)|BIOLOGICAL: CordSTEM-DD (2.1 x 10^7 cells)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ACT-451840:|OTHER: Plasmodium falciparum-infected human erythrocytes:|DRUG: Artemether 20 mg and lumefantrine 120mg combination tablet:|DRUG: Primaquine:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dentoskeletal Effects of the Expander With Differential Opening and the Fan-type Expander
Status: COMPLETED
Conditions: Malocclusion|Crossbite (Posterior)
Interventions: DEVICE: Differential Expansion|DEVICE: Fan-Fype Expander
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT