pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exploring the Effectiveness of Digital Anti-stigma Therapy on Illness Perception and Perceived Stigma in Patients With Schizophrenia and Their Primary Caregivers
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia
Interventions: OTHER: Participants will use 3D glasses to view VR educational information|OTHER: routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Pain and Stress Perception and Dry Needling Technique Application
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Dry needling of lumbar iliocostalis muscle|OTHER: Sham dry needling lumbar iliocostalis muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of CO-OP Approach on Activity and Participation of Brazilian Children With Developmental Coordination Disorder
Status: COMPLETED
Conditions: Motor Skills Disorders|Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: standard CO-OP Approach|BEHAVIORAL: standard CO-OP Approach plus coaching parents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant I.V. Iron Therapy During Erythropoetin Treatment of Anemic Patients With Lymphoproliferative Disorders.
Status: COMPLETED
Conditions: Anemia|Multiple Myeloma|Non Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: Neo-Recormon and Venofer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety and Tolerability Study in Subjects With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Bapineuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of PXS-5505 Combined With First Line Atezolizumab Plus Bevacizumab For Treating Patients With Unresectable Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma|Cancer of Liver
Interventions: DRUG: PXS-5505 and Atezolizumab and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Alectinib|DRUG: Atezolizumab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Entrectinib|DRUG: Cobimetinib|DRUG: Vemurafenib|DRUG: Bevacizumab|DRUG: Divarasib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information Processing Modification in PTSD (Oct. 18)
Status: COMPLETED
Conditions: Stress Disorders, Post-traumatic
Interventions: BEHAVIORAL: Attention Bias Modification (ABM)|BEHAVIORAL: Attention Control Condition (ACC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Teriparatide Compared to Risedronate on Back Pain in Women With a Spine Fracture Caused by Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal|Back Pain|Spinal Fracture
Interventions: DRUG: teriparatide|DRUG: risedronate|DRUG: placebo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decrease Emergence Agitation and Provide Pain Relief for Children Undergoing Tonsillectomy & Adenoidectomy
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: dexmedetomidine|DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Real-life Effectiveness and Cost-effectiveness of Qvar Versus FP and BDP in the Management of COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Extra-fine hydrofluoroalkane beclomethasone MDI|DRUG: Chlorofluorocarbon beclomethasone metered dose inhaler|DRUG: Fluticasone propionate metred dose inhaler|DRUG: Fluticasone propionate metred dose inhaler|DRUG: Hydrofluoroalkane beclomethasone metred dose inhaler|DRUG: Chlorofluorocarbon beclomethasone dipropionate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Interscalene Brachial Plexus Block With Liposomal Bupivacaine for Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Shoulder Pain|Rotator Cuff Tear
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine 0.25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CardioBBEAT - Randomized Controled Trial to Evaluate the Health Economic Impact of Remote Patient Monitoring
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DEVICE: Remote patient monitoring (Motiva)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TDENV PIV and LAV Dengue Prime-boost Strategy Using AS03B Adjuvant
Status: WITHDRAWN
Conditions: Dengue
Interventions: BIOLOGICAL: TDENV-PIV|BIOLOGICAL: TDENV-F17|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2a to Evaluate the Safety of MEDI8852 in Adults With Uncomplicated Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Oseltamivir|DRUG: MEDI8852|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Playmaker 3D Printed Knee Extender
Status: TERMINATED
Conditions: ACL|ACL Injury
Interventions: DEVICE: 3D printed knee extender device|OTHER: Standard Prehabilitation Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D as add-on Therapy for Vitamin D Insufficient Patients With Severe Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma
Status: COMPLETED
Conditions: Advanced Bladder Urothelial Carcinoma|Advanced Ureter Urothelial Carcinoma|Metastatic Bladder Urothelial Carcinoma|Metastatic Renal Pelvis Urothelial Carcinoma|Metastatic Ureter Urothelial Carcinoma|Metastatic Urethral Urothelial Carcinoma|Metastatic Urothelial Carcinoma|Recurrent Bladder Urothelial Carcinoma|Recurrent Renal Pelvis Urothelial Carcinoma|Recurrent Ureter Urothelial Carcinoma|Recurrent Urethral Urothelial Carcinoma|Stage III Bladder Cancer AJCC v8|Stage III Renal Pelvis Cancer AJCC v8|Stage III Ureter Cancer AJCC v8|Stage III Urethral Cancer AJCC v8|Stage IV Bladder Cancer AJCC v8|Stage IV Renal Pelvis Cancer AJCC v8|Stage IV Ureter Cancer AJCC v8|Stage IV Urethral Cancer AJCC v8|Stage IVA Bladder Cancer AJCC v8|Stage IVB Bladder Cancer AJCC v8|Unresectable Bladder Urothelial Carcinoma|Unresectable Renal Pelvis Urothelial Carcinoma|Unresectable Ureter Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Glycosylated Recombinant Human Interleukin-7|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography and Computed Tomography Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: DS-1062a|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Game: A Scale to Evaluate the Perioperative Cognitive Function
Status: COMPLETED
Conditions: Cognition Disorders|Impaired Cognition|Self-Assessment
Interventions: DEVICE: MentalPlus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Zilebesiran in Japanese Patients With Mild to Moderate Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild to Moderate Hypertension
Interventions: DRUG: Zilebesiran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Aberrometry vs Conventional Intraocular Lens Calculation, a Prospective Study.
Status: RECRUITING
Conditions: Intraocular Lens Implantation|Cataract|Humans|Ocular, Refraction
Interventions: DEVICE: Intraoperative aberrometer|OTHER: Preoperative intraocular lens calculation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nitrous Oxide Induction Induces Amnesia in Pediatric Patients
Status: COMPLETED
Conditions: Amnesia
Interventions: BEHAVIORAL: Explicit and Implicit memory|DRUG: 0% nitrous oxide, 30% nitrous oxide and 60% nitrous oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Pneumococcal Vaccination of Multiple Myeloma Patients on Novel Agents
Status: COMPLETED
Conditions: Multiple Myeloma|Pneumococcal Infection|Febrile Neutropenia|Pneumococcal Pneumonia
Interventions: BIOLOGICAL: Vaccination with pneumococcal conjugate vaccine (PCV13)|DRUG: Standard Antibacterial Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Bevacizumab With Carboplatin and Paclitaxel Chemotherapy for the First-Line Treatment of Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Potential of Candesartan to Retard the Progression of Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DRUG: candesartan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Certified Nursing Assistants' Wellbeing
Status: COMPLETED
Conditions: Stress and Burnout
Interventions: BEHAVIORAL: 8-Week Mindful Self-Compassion (MSC)|BEHAVIORAL: 6-Week Mindful Self-Compassion (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topotecan in Treating Patients With Gynecologic Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Fallopian Tube Cancer|Ovarian Cancer|Sarcoma|Vaginal Cancer|Vulvar Cancer
Interventions: DRUG: topotecan hydrochloride|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction
Status: COMPLETED
Conditions: Acute ST Elevation Myocardial Infarction
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Hypoabsorption Techniques for the Treatment of Type III Obesity (OASIS)
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: metabolic surgery (SADIS and OAGB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation
Status: RECRUITING
Conditions: Thalassemia Major
Interventions: DIETARY_SUPPLEMENT: Taurine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of Diractin® for the Treatment of Osteoarthritis (OA) of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ketoprofen in Diractin®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib (Velcade®), Lenalidomide (Revlimid®) and IV Busulfan (Busilvex®) in Patients Under 65 Years Old
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: bortezomib (Velcade ®)|DRUG: lenalidomide (Revlimid®)|DRUG: busulfan (Busilvex ®)|DRUG: Dexamethasone acetate|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baker Gordon Syndrome Natural History Study
Status: RECRUITING
Conditions: Rare Diseases|Autism or Autistic Traits|Development Delay|SYT-SSX Fusion Protein Expression|Sleep Disorder|Epilepsy, Generalized|Motor Delay
Interventions: DIAGNOSTIC_TEST: Brain Magnetic Resonance Imaging (MRI)|GENETIC: Whole Genome Sequencing|OTHER: Induced Pluripotential Stem Cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Effect of θ Burst Magnetic Stimulation on Clinical Symptoms of Alzheimer Disease
Status: COMPLETED
Conditions: Repetitive Transcranial Magnetic Stimulation
Interventions: OTHER: θ burst transcranial magnetic stimulation|DRUG: Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions to Increase HBV Vaccinations in Sexually Transmitted Disease (STD) Clinics
Status: COMPLETED
Conditions: Hepatitis B Virus
Interventions: BEHAVIORAL: Non-Framed-Offered|BEHAVIORAL: Non-Framed-Recommended|BEHAVIORAL: Gain-Framed-Offered|BEHAVIORAL: Gain-Framed-Recommended|BEHAVIORAL: Loss-Framed-Offered|BEHAVIORAL: Loss-Framed-Recommended
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: E1K Intra Articular(IA) Treatment for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthrosis
Interventions: DRUG: E1K 1,200 ㎍/joint|DRUG: E1K 2,400 ㎍/joint|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of a New Daily Disposable Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: delefilcon A contact lens|DEVICE: filcon II 3 contact lenses|DEVICE: narafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart Function
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lucerastat (Treatment A)|OTHER: Placebo|DRUG: Moxifloxacin|DRUG: Lucerastat (Treatment B)|DRUG: Lucerastat (Treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase II Study of the Association of Glivec® Plus Gemzar® in Patients With Unresectable, Refractory, Malignant Mesothelioma
Status: UNKNOWN
Conditions: Mesothelioma
Interventions: DRUG: Imatinib mesylate plus Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Beneficial Effects of a Probiotic Product in Healthy Adult Subjects.
Status: COMPLETED
Conditions: Disbiosis|Abdominal Pain|Constipation|Diarrhea|Stress
Interventions: DIETARY_SUPPLEMENT: Lactoflorene plus|DIETARY_SUPPLEMENT: Placebo Lactoflorene plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIYELA - Bexsero Immunisation in Young Women in Africa
Status: NOT_YET_RECRUITING
Conditions: Gonorrhea|Gonorrhea of Pharynx|Gonorrhea of Anus|Gonorrhea of Cervix
Interventions: BIOLOGICAL: Bexsero|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I, Multicenter, Randomized, Double-Blind, Placebo-Controlled HIV-1 Vaccine Trial to Evaluate the Safety and Immunogenicity of MN Recombinant Soluble gp120/HIV-1 (rsgp120/HIV-1) (Genentech) in Combination With QS21 Adjuvant and/or Alum in Healthy Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Aluminum hydroxide|BIOLOGICAL: QS-21|BIOLOGICAL: rgp120/HIV-1MN
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Solifenacin Succinate Versus Fesoterodine A Comparison Trial for Urgency Symptoms
Status: UNKNOWN
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: solifenacin succinate|DRUG: fesoterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Antiplatelet Therapy During Percutaneous Coronary Intervention in Patients With Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Abciximab|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Protective Effect of α-Keto Acid With Low-protein Diet on Renal Function in PD Patients
Status: COMPLETED
Conditions: Peritoneal Dialysis
Interventions: DIETARY_SUPPLEMENT: α-Keto Acid with low protein diet|DIETARY_SUPPLEMENT: Normal protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic and Prognostic Utility of Pentraxin 3 in Patients With Acute STEMI Undergoing Primary PCI
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: pentraxin 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy
Status: COMPLETED
Conditions: Anesthesia|Pediatrics|Biliary Atresia
Interventions: DRUG: Norepinephrine Bitartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Feasibility and Cost-effectiveness of Genotype-directed Individualized Dosing of Fluoropyrimidines
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Fluoropyrimidine (capecitabine or 5-fluorouracil)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Multicenter Study of Talimogene Laherparepvec in Classic or Endemic Kaposi Sarcoma
Status: UNKNOWN
Conditions: Kaposi Sarcoma
Interventions: DRUG: Talimogene laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: anti-IGF-1R recombinant monoclonal antibody MK-0646|DRUG: cisplatin|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Evaluate the Safety, Tolerability and PK of GB1211 in Healthy Subjects
Status: COMPLETED
Conditions: Safety and Tolerability
Interventions: DRUG: GB1211|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Imiquimod and Tumor Lysate Vaccine Immunotherapy in Adults With High Risk or Recurrent Grade II Gliomas
Status: COMPLETED
Conditions: High Risk WHO Grade II Glioma|Recurrent/Post-Chemotherapy WHO Grade II Glioma
Interventions: BIOLOGICAL: Tumor Lysate Vaccine|DRUG: Imiquimod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irofulven in Treating Patients With Recurrent or Persistent Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: irofulven
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Antiviral Efficacy, Pharmacokinetics and Safety of BILN 2061 ZW in Patients With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BILN 2061 W, low dose|DRUG: BILN 2061 W, medium dose|DRUG: BILN 2061 W, high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of PEA-LUT on Frontal Lobe Functions and GABAergic Transmission in Long-Covid Patients
Status: COMPLETED
Conditions: Fatigue|Cognitive Deficit|COVID-19|Neurophysiologic Abnormality
Interventions: DIETARY_SUPPLEMENT: palmitoylethanolamide co-ultramicronized with antioxidant flavonoid luteolin (PEA-LUT)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of TAP (Transversus Abdominis Plane) Block for Abdominal Aortic Surgery
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm|Abdominal Aortic Stenosis|Syndrome, Leriche
Interventions: OTHER: ropivacaine|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Zimmer Puros® Allograft vs. Creos™ Allograft for Alveolar Ridge Preservation
Status: COMPLETED
Conditions: Alveolar Bone Grafting|Allograft|Dental Extraction|Dental Implant|Socket Preservation
Interventions: DEVICE: Zimmer Puros Cancellous Allograft|DEVICE: Nobel Biocare Creos Cancellous Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complete Shielding of Multivitamins to Reduce Toxic Peroxides in the Parenteral Nutrition: A Pilot Study
Status: COMPLETED
Conditions: Parenteral Nutrition|Infant, Premature, Diseases|Infant, Newborn, Disease|Lung Diseases|Respiratory Tract Disease|Bronchopulmonary Dysplasia|Pathologic Processes
Interventions: OTHER: Photo-protection|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
Status: RECRUITING
Conditions: Functional Mitral Regurgitation|Heart Failure|Mitral Valve Insufficiency|Heart Diseases|Cardiovascular Diseases|Heart Valve Diseases
Interventions: DEVICE: Carillon Mitral Contour System|OTHER: Guideline Directed Heart Failure Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicine Including a 12 Weeks Extension and an Open-label 48 Weeks Extension Study
Status: COMPLETED
Conditions: Acute Gout
Interventions: DRUG: Canakinumab 150 mg|DRUG: Triamcinolone acetonide 40 mg|DRUG: Placebo to canakinumab|DRUG: Placebo to triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 6(S)-5-MTHF Among Serotonin Reuptake Inhibitor(SSRI)-Resistant Outpatients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: OTHER: 6(S)-5-MTHF (a Medical Food)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of A4368 in Healthy Subjects
Status: COMPLETED
Conditions: Health Subjects
Interventions: DRUG: A4368 or placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Intubation Devices
Status: UNKNOWN
Conditions: Intubation
Interventions: DEVICE: The Miller Laryngoscope|DEVICE: The Bonfils intubation fibrescope|DEVICE: The GlideScope Ranger|DEVICE: The Supraglottic Airway Laryngopharyngeal Tube (SALT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T-GENVIH-003 LTFU (Long Term Follow Up) Study
Status: COMPLETED
Conditions: Hernia|Hernia, Ventral|Pathological Conditions, Anatomical|Hernia, Abdominal
Interventions: DEVICE: Integra® Gentrix® Surgical Matrix
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bendamustine and Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Non-Hodgkin's Lymphoma (NHL)
Status: WITHDRAWN
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Temsirolimus|DRUG: Bendamustine|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Neck Flexion on Esophagogastric Anastomotic Leakage After MIE
Status: UNKNOWN
Conditions: Esophageal Neoplasms|Esophagectomy|Anastomotic Leak
Interventions: PROCEDURE: neck flexion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abobotulinum Toxin and Neubotulinum Toxin Injection in Cerivical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: Neuronox(R)|DRUG: Dysport (R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etodalac, Etoricoxib and Dexamethasone for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery
Status: UNKNOWN
Conditions: Trismus|Edema|Pain
Interventions: DRUG: Etodalac, Etoricoxib and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rosiglitazone (Avandia) vs. Placebo for Androgen Dependent Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Prostate Cancer
Interventions: DRUG: Rosiglitazone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Mixed Venous Blood Oxygen Saturation Obtained With a Novel Mathematical Equation
Status: TERMINATED
Conditions: Mixed Venous Oxygen Saturation|Tissue Oxygenation
Interventions: DEVICE: Cerebral/Somatic Tissue Oximeter device|DEVICE: Pulmonary artery catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Checkpoint Inhibitors|Metastatic Solid Tumor|Nonsmall Cell Lung Cancer|Melanoma|Renal Cell Carcinoma|Gastrointestinal Cancer|Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate the Pharmacodynamic Effects of IP2015 in Healthy Male Subjects Using the Intradermal Capsaicin Model
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: IP2015, dose 1|DRUG: IP2015, dose 2|DRUG: Placebo|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tamsulosin as Adjuvant Treatment Prior to Endoscopic Ureterolithotomy
Status: TERMINATED
Conditions: Ureterolithiasis|Ureteral Calculi|Urolithiasis
Interventions: DRUG: Tamsulosin Hydrochloride 0.4 milligrams|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feeding Children Nasogastrically Versus Nasojejunally While Receiving Noninvasive Positive Pressure Ventilation
Status: COMPLETED
Conditions: Respiratory Insufficiency|Pneumonia, Aspiration|Nutrition Disorders
Interventions: OTHER: Route of feeding (nasogastric vs. nasojejunal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of HM61713 for the Treatment of ≥2nd Line T790M Mutation Positive Adenocarcinoma of the Lung
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: HM61713
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study in French Practice to Evaluate Improvements in Walking and Pain Relief in Patients Treated With Endovascular Treatment of de Novo Lesions of the Femoropopliteal Artery Above the Knee With LUTONIX®035 or RANGER TM Active Ballon
Status: RECRUITING
Conditions: Drug-coated Balloon Catheter
Interventions: OTHER: 6-minute walk test|OTHER: WIQ functional questionnaire|OTHER: quality of life questionnaires (EQ5D5L and SF-36)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Gastrostomy-Related Wound Infection by Vancomycin in Carriers of Methicillin-Resistant Staphylococcus Aureus.
Status: UNKNOWN
Conditions: Wound Infection
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Fluid Capture Efficiency of the Total Capture Drape Versus a Standard Drape for Hysteroscopy
Status: TERMINATED
Conditions: Hysteroscopic Surgery
Interventions: DEVICE: Total Capture Drape|DEVICE: Standard Hysteroscopy Drape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Insignia ™ Versus Standard Orthodontic Treatment With Damon Q Brackets
Status: COMPLETED
Conditions: Orthodontic Treatment|Fixed Appliances|Insignia|DamonQ Brackets
Interventions: DEVICE: Damon self ligating orthodontic bracket|DEVICE: Insignia self ligating orthodontic bracket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Combination of Three Antihypertensive Drugs
Status: UNKNOWN
Conditions: Arterial Hypertension
Interventions: DRUG: Tripliam (perindopril, indapamide, amlodipine)|DRUG: Reaptan (perindopril, amlodipine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Increasing Calcium Dietary Intake Helps to Control Blood Presure and Body Weight
Status: UNKNOWN
Conditions: Hypertension|Body Weight
Interventions: DIETARY_SUPPLEMENT: LOW-SODIUM LOW LIPID CALCIUM RICH DIET|DIETARY_SUPPLEMENT: LOW-SODIUM LOW LIPID DIET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consumption of Whole Grains and Legumes Modulates the Genetic Effect of the APOA5 -1131C Variant
Status: COMPLETED
Conditions: Subjects With Mild Hypertriglyceridemia in Type 2 DM
Interventions: DIETARY_SUPPLEMENT: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Between 2% Lidocaine Gel and 5% Tetracaine Eye Drop as Topical Anesthesia in Phacoemulsification
Status: COMPLETED
Conditions: Adult Patients Undergoing Phacoemulsification With Topical Anesthesia
Interventions: DRUG: lidocaine gel|DRUG: tetracaine eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I/II Study of Lenalidomide and Obinutuzumab With CHOP for Diffuse Large B Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Obinutuzumab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perform® Humeral System - Fracture Study (PFX)
Status: RECRUITING
Conditions: Traumatic Arthropathy of Shoulder|Fracture Humerus|Traumatic Arthritis|Revision of Other Devices if Sufficient Bone Stock Remains
Interventions: DEVICE: Tornier Perform® Humeral System - Fracture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics Study of Treatment With CHF 5074 in Healthy Young Male Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: CHF 5074|DRUG: placebo|DRUG: CHF 5074|DRUG: CHF 5074|DRUG: CHF 5074|DRUG: CHF 5074|DRUG: CHF 5074
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Drug-drug Interaction Study of Dapagliflozin With Voglibose in Japanese Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Fluorescent Navigation Technology in Radical Resection of Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Resectable Pancreatic Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: Injection of fluorescent developer (anti-EGFR-IR800CW)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Find the Percentage of Cases Retaining COVID-19 IgG Antibodies 45-65 After They Have Tested Positive
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: Repeat SARS-CoV-2 IgG antibodies at 45-65 days
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Combined Action Between Natrecor and Furosemide on Kidney and Neurohormone Responses in Chronic Heart Failure: A Phase-IV study704.351 / DSS
Status: COMPLETED
Conditions: Congestive Heart Failure|Chronic Heart Failure
Interventions: DRUG: nesiritide, furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant S-1 and Concurrent Radiotherapy for Borderline Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: S-1|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-center Study on Reducing Postoperative Pulmonary Complications in Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pulmonary Complications
Interventions: OTHER: Application of integrated intervention system programs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid
Status: UNKNOWN
Conditions: Melasma
Interventions: DRUG: Modified Jessner's solution|DRUG: Glycolic acid|DRUG: Trichloroacetic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selumetinib (AZD6244: ARRY-142886) (Hyd-Sulfate) in Metastatic Uveal Melanoma (SUMIT)
Status: COMPLETED
Conditions: Metastatic|Uveal Melanoma
Interventions: DRUG: 75mg selumetinib|DRUG: placebo|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Select the Dose and Evaluate the Effectiveness and Safety of the Drug Refralon®, Tablets, 1 mg for Long-term Use to Prevent Recurrence of Atrial Fibrillation/Flutter After Terminating Its Persistent Form
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: 4-Nitro-N-[(1RS)-1-(4-fluorophenyl)-2-(1-ethylpiperidin-4-yl)ethyl]benzamide hydrochloride|DRUG: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Stereotactic Body Radiation Therapy to Microwave Ablation for the Treatment of Localized Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Carcinoma, Hepatocellular
Interventions: RADIATION: Microwave Ablation (MWA)|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Restricted Feeding in Male Runners
Status: COMPLETED
Conditions: Fasting|Intermittent Fasting|Athletic Performance|Cardiovascular Risk Factor|Resting Energy Expenditure
Interventions: BEHAVIORAL: Time Restrictive Feeding|BEHAVIORAL: Traditional Eating Pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus
Status: RECRUITING
Conditions: Keratoconus
Interventions: COMBINATION_PRODUCT: Riboflavin and Sodium Iodide solution and Ultraviolet-A treatment|COMBINATION_PRODUCT: Placebo and sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of M3 in Predicting Colorectal Advanced Adenoma Recurrence (M3-AA)
Status: RECRUITING
Conditions: Colorectal Adenoma|Advanced Adenoma|Colorectal Polyp
Interventions: DIAGNOSTIC_TEST: M3|DIAGNOSTIC_TEST: FIT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-based Exercise in COVID-19 Survivors
Status: UNKNOWN
Conditions: Covid19|SARS (Severe Acute Respiratory Syndrome)|SARS-CoV Infection
Interventions: OTHER: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Curcumin on Microvascular Response and Tissue Oxygenation
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Curcumin powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Two-field or Three-field Lymphadenectomy on Overall Survival in Middle and Lower Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DIAGNOSTIC_TEST: Since the data were collected retrospectively, there were no interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lowering Total Immunosuppressive Load in Renal Transplant Recipients More Than 12 Months Posttransplant
Status: TERMINATED
Conditions: Renal Transplantation
Interventions: DRUG: Mycophenolate mofetil withdrawal|DRUG: Cyclosporione A withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimal Dose of Intravenous Oxycodone for Endotracheal Intubation
Status: COMPLETED
Conditions: Intubation Complication|Blood Pressure
Interventions: DRUG: saline|DRUG: 0.05 mg/kg of oxycodone|DRUG: 0.1 mg/kg of oxycodone|DRUG: 0.15 mg/kg of oxycodone|DRUG: 0.2 mg/kg of oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UTERINE EVALUATION FOR THE IDENTIFICATION OF PATHOLOGY. This Study Will Compare the Intrauterine Pathology Detection Rate Between Standard of Care Hydrosonography, and a New Visual Saline Infusion Device Providing Direct Visualization of the Uterus.
Status: RECRUITING
Conditions: Hysteroscopy|Hysteroscopy Technique|Fertility Issues|Uterus Abnormal|Gynecology|Visualization|Infertility Female
Interventions: DEVICE: Visual Saline Infusion|DEVICE: Hydrosonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of "Persons With Disability Friendly Nursing Education Program"
Status: UNKNOWN
Conditions: Nurse-Patient Relations|Nurse's Role|Nursing Caries
Interventions: BEHAVIORAL: "Persons With Disability Friendly Nursing Education Program"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Large Diameter Advanta™ V12 Covered Stent Trial for Coarctation of the Aorta
Status: COMPLETED
Conditions: Coarctation of the Aorta
Interventions: DEVICE: Large Diameter Advanta™ V12 Covered Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma-focused Cognitive-behavioural Therapy(TF-CBT) for Children: A Study of Process and Outcome.
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: OTHER: TF-CBT|OTHER: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The DISSECT Study: Effect of Peri-aDventItial SMA diSsECtion on Margin sTatus During Pancreaticoduodenectomy for Resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: PROCEDURE: No Periadventitial dissection of the SMA|PROCEDURE: Periadventitial dissection of the SMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dynamic Taping With Exercise on Neuromuscular Control in Individuals With Subacromial Impingement
Status: RECRUITING
Conditions: Shoulder Impingement Syndrome
Interventions: PROCEDURE: Motor control exercise with dynamic taping|PROCEDURE: Motor control exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT