pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA)
Status: COMPLETED
Conditions: End Stage Liver Disease
Interventions: DEVICE: Bodystat Quadscan 4000|DEVICE: bodystat quadscan 400
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: CG-806
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Usage of a Moisturizing Lotion (Cetaphil® Moisturizing Lotion) to Limit the Skin Irritation Linked to the Set-Up of a Treatment by Topical Retinoid (Differin® Gel 0,1%) in Healthy Subjects of Chinese Origins
Status: COMPLETED
Conditions: Healthy Skin
Interventions: DRUG: adapalen 0.1%|OTHER: Cetaphil®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus)
Status: TERMINATED
Conditions: Kidney Neoplasms|Kidney (Renal Cell) Cancer
Interventions: DRUG: Everolimus|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICU Trial in Critical Ill COVID-19 Patients
Status: COMPLETED
Conditions: Risk Factor, Cardiovascular|Covid19|Critical Illness|Course Illness
Interventions: DIAGNOSTIC_TEST: Biomarker (TropT, Myoglobin, CK, CK-MB, LDH, D-dimer, CRP, PCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose-Ranging Study Evaluating the Efficacy, Safety, and Tolerability of GSK2140944 in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria Gonorrhoeae
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: GSK2140944
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Based Task Specific Exercises in Patients With Hand Flexor Tendon Injury
Status: COMPLETED
Conditions: Tendon Injury - Hand|Flexor Tendon Rupture
Interventions: OTHER: Virtual Reality Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Teduglutide in Japanese Participants With Short Bowel Syndrome
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: Teduglutide|DEVICE: Syringe|DEVICE: Needle|DEVICE: Vial Adapter for Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency
Status: RECRUITING
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: KB408 (Nebulization)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Injection of PRP During Repair of Disrupted Surgical Wounds
Status: COMPLETED
Conditions: Role of Platelet Rich Plasma in Wound Healing
Interventions: PROCEDURE: Platelet rich plasma infiltration in the wound edges|PROCEDURE: Closure of wound without platelet rich plasma infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Whey Consumption on Insulin Resistance, Cortisol, Crp, Albumin Level and Healing Quality Before Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Crp|Insulin Resistance|Cortisol; Hypersecretion|Albus; Lichen|Quality of Life
Interventions: DIETARY_SUPPLEMENT: whey protein intake before surgery|DIETARY_SUPPLEMENT: Water before surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer
Status: TERMINATED
Conditions: HER2-positive Breast Cancer|Breast Cancer Metastatic
Interventions: DRUG: Palbociclib 75mg|DRUG: Letrozole 2.5mg|DRUG: T-DM1|DRUG: Palbociclib 100mg|DRUG: Palbociclib 125mg|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Bortezomib (VELCADE) in Combo With Pralatrexate in Relapsed/Refractory MM
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: velcade|DRUG: Pralatrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Family-Centered Empowerment Model
Status: COMPLETED
Conditions: Acute Myocardial Infarction: Rehabilitation Phase
Interventions: OTHER: Family-centered empowerment model|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The RESTING Insomnia Study: Randomized Controlled Study on Effectiveness of Stepped-Care Sleep Therapy
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: ONLINE ONLY|BEHAVIORAL: STEPPED CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Delayed Graft Function Using Eculizumab Therapy (PROTECT Study)
Status: COMPLETED
Conditions: Delayed Graft Function
Interventions: DRUG: Eculizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft Versus Host Disease|GVHD
Interventions: DRUG: tacrolimus|DRUG: sirolimus|DRUG: fludarabine|DRUG: busulfex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Evaluate the Safety of Ospemifene
Status: COMPLETED
Conditions: Atrophy|Vaginal Diseases
Interventions: DRUG: Ospemifene 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy With Autologous Stem Cell Transplantation in Poor Prognosis Germ-cell Tumors: TAXIF II
Status: COMPLETED
Conditions: Testicular Neoplasms
Interventions: DRUG: epirubicin|PROCEDURE: high-dose and autologous stem cell transplantation|DRUG: paclitaxel|DRUG: etoposide|DRUG: ifosfamide|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG-IFN Plus Ribavirin Combination Therapy for Older Patients
Status: UNKNOWN
Conditions: Hepatitis C Virus
Interventions: DRUG: Pegylated interferon alpha-2b plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Measurement of Compartment Pressure: Reliability
Status: ACTIVE_NOT_RECRUITING
Conditions: CEC Syndrome
Interventions: DEVICE: Compremium Compressibility Measurement|PROCEDURE: Treadmill Running|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Tegaderm HP and CHG in Major Catheter Related Infections and Dressing Detachment
Status: COMPLETED
Conditions: Catheter-Related Infections
Interventions: PROCEDURE: Tegaderm, Tegaderm HP, Tegaderm CHG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine and Zinc With Either Azithromycin or Doxycycline for Treatment of COVID-19 in Outpatient Setting
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Azithromycin|DRUG: Zinc Sulfate|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of OT202 in Treating Moderate to Severe Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: OT202 conc 0.5%|DRUG: OT202 conc 0.1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant Dostarlimab Plus Capecitabine Plus Oxaliplatin (CAPEOX) Vs CAPEOX With Previously Untreated T4N0 or Stage III Mismatch Repair Proficient (MMRp)/Microsatellite Stable (MSS) Colon Cancer
Status: NOT_YET_RECRUITING
Conditions: Neoplasms, Colon
Interventions: BIOLOGICAL: Dostarlimab|DRUG: CAPEOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Hypothermia With IntraVascular Temperature Management (IVTM) in Post-Cardiogenic Cardiac Arrest and Post-Return of Spontaneous Circulation Patients in Japan
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DEVICE: ZOLL Intravascular Temperature Management System (IVTM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Localized NB-UVB (Levia®) in the Treatment of Plaque-psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DEVICE: Levia Narrow Band UVB|DEVICE: Levia sham/visible-light source
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Efficacy of Risankizumab Using a New Formulation in Participants With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Risankizumab|DRUG: Placebo solution for risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Protective Effect of a Formula Supplemented With Fermented Matrices on the Risk of Developing Neonatal Sepsis
Status: UNKNOWN
Conditions: Neonatal Sepsis
Interventions: DIETARY_SUPPLEMENT: Preterm Infants - fed fermented formula|OTHER: Preterm Infants - fed standard formula|OTHER: Pre-term Infants - breastfed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sunitinib in Treating Patients With Brain Metastases Caused by Kidney Cancer or Melanoma
Status: COMPLETED
Conditions: Kidney Cancer|Melanoma (Skin)|Metastatic Cancer
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the QT / QTc Interval Prolongation Potential of Vericiguat
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Vericiguat (BAY1021189)|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azithromycin in the Treatment of Cryptosporidiosis in Patients With Acquired Immune Deficiency Syndrome (AIDS): A Randomized, Multi-Center, Placebo-Controlled, Double-Blind Study
Status: COMPLETED
Conditions: Cryptosporidiosis|HIV Infections
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
Status: COMPLETED
Conditions: HIV Infections|Risk Reduction|Risk Behavior|Risky Health Behavior|STD|HIV Seropositivity|HIV Infection Primary
Interventions: PROCEDURE: HIV testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effect of Helicobacter Pylori Eradication Before and After the Training of Gastroenterologists
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: BEHAVIORAL: Standardized training on Helicobacter pylori eradication treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous/Allogeneic TGFbeta-resistant LMP-specific CTL, Lymphoma (TGF-beta)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Hodgkin's Disease|Relapse|Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: TGFbeta resistant LMP-specific CTLs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HBsAg Loss Adding Pegylated Interferon in HBeAg-negative Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B (HBeAg-negative)
Interventions: DRUG: Pegylated interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MRI and Stable Isotope Tracer Studies for Detecting the Progression of Non-Alcoholic Steatohepatitis (NASH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging|OTHER: Stable Isotope Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transfusional Iron Overload
Status: COMPLETED
Conditions: β-thalassemia|Transfusional Iron Overload
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Identification in the Axilla of Women With Breast Cancer Using Ultrasound and Iron Injection
Status: WITHDRAWN
Conditions: Breast Neoplasm|Carcinoma, Ductal, Breast|Carcinoma, Intraductal, Noninfiltrating
Interventions: PROCEDURE: Iron-tracer guided axillary ultrasound and biopsy|DRUG: Iron tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS) Asian/Asian American Women Supplement
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Cancer|Human Papillomavirus Infection
Interventions: BEHAVIORAL: Telephone Recall|BEHAVIORAL: Mailed HPV Self-Sampling Kit|BEHAVIORAL: Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Bioequivalence Study of Colchicine Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Colchicine|DRUG: Colchicine|DRUG: Colchicine/Probenecid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Biomarkers in Patients With High-Risk Melanoma Receiving High-Dose Interferon Therapy
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: recombinant interferon alfa|GENETIC: proteomic profiling|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3)
Status: COMPLETED
Conditions: Type II Diabetes|Dyslipidemia
Interventions: DRUG: Metformin/Atorvastatin 1500mg/40mg, QD|DRUG: Metformin 1500mg, QD|DRUG: Atorvastatin 40mg, QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Repeat Doses of Isavuconazole on Cardiac Repolarization
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Photobiomodulation Therapy in Exercise Capacity Assessed by 6MST in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD
Interventions: DEVICE: Photobiomodulation Therapy (PBMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoantigen Reactive T Cells Combined With SHR-1210 for Chinese Patients With Advanced Refractory Solid Tumors
Status: UNKNOWN
Conditions: Advanced Malignant Solid Tumor
Interventions: BIOLOGICAL: Neoantigen Reactive T Cells(NRTs)|BIOLOGICAL: SHR-1210|DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compliance, Tolerance and Acceptability of a Tablet Protein Substitute for the Dietary Management of Phenylketonuria
Status: WITHDRAWN
Conditions: Phenylketonurias
Interventions: DIETARY_SUPPLEMENT: Phenylalanine-free protein substitute tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Submandibular Gland Preservation in Neck Dissection
Status: RECRUITING
Conditions: Neck Dislocation|Oral Cancer
Interventions: PROCEDURE: modified neck dissection|PROCEDURE: traditional neck dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CNI Transient Replacement by Belatacept From 3 to 12 Months Post Transplantation in Patients With Early Graft Dysfunction
Status: UNKNOWN
Conditions: Chronic Kidney Failure
Interventions: DRUG: Belatacept 250 Milligram Intravenous Powder for Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Evaluation of Multi-modality Algorithm for Non-metastatic Adenocarcinoma of Pancreas or Ampulla
Status: TERMINATED
Conditions: Ductal Adenocarcinoma of Pancreas|Adenocarcinoma of Ampulla
Interventions: DRUG: Gemcitabine and nanoparticle albumin bound paclitaxel|DRUG: 5-fluorouracil and irinotecan|RADIATION: Preoperative chemoradiation|PROCEDURE: Definitive resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SMV + SOF With/Without RBV for IFN-II Patients With CHC
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Simeprevir|DRUG: Sofosbuvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium to Reduce Implantable Cardioverter Defibrillator (ICD) Shocks and Improve Patient's Quality of Life.
Status: UNKNOWN
Conditions: Arrhythmia|Quality of Life|Hypomagnesemia
Interventions: DRUG: Magnesium L-lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab Plus Pemetrexed and Cisplatin (PemCisP) Versus PemCis in the First-line Treatment of Patients With Non-small Cell Lung Cancer
Status: SUSPENDED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Panitumumab|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dalpiciclib Combined With Letrozole in the Maintenance Treatment of HR Positive and HER2 Negative Metastatic Breast Cancer After First-line Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dalpiciclib combined with Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation of EA-230 Following On-pump Coronary Artery Bypass Grafting (CABG)
Status: UNKNOWN
Conditions: Systemic Inflammatory Response Syndrome|Coronary Artery Bypass Grafting
Interventions: DRUG: EA-230|OTHER: Placebo (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atrasentan in Patients With Proteinuric Glomerular Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: IgA Nephropathy|Focal Segmental Glomerulosclerosis|Alport Syndrome|Diabetic Kidney Disease|Diabetic Nephropathy Type 2|Immunoglobulin A Nephropathy
Interventions: DRUG: Atrasentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPARATIVE EFFECTS OF ELDOA VERSES UPPER THORACIC MOBILIZATION AND MOBILITY EXERCISE FOR THE TREATMENT OF FHP
Status: ACTIVE_NOT_RECRUITING
Conditions: Postural, Thoracic Kyphosis|Postural; Defect
Interventions: OTHER: ELDOA ,UPPER THORACIC MOBILIZATION AND MOBILITY EXERCISE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Research on Shenfu Injection in Septic Patients
Status: RECRUITING
Conditions: Sepsis
Interventions: DRUG: Shen-Fu|DRUG: Norepinephrine (NE)，antibiotics，fluid resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Suprachoroidal Triamcinolone Acetonide Via Microneedle to Treat Uveitis
Status: COMPLETED
Conditions: Uveitis|Intermediate Uveitis|Posterior Uveitis|Panuveitis|Noninfectious Uveitis
Interventions: DRUG: triamcinolone acetonide (Triesence®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve During Thyroid Surgery
Status: TERMINATED
Conditions: Carcinoma, Papillary, Follicular
Interventions: DEVICE: Using Neuromonitoring to find EBSLN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Plecanatide in Adolescents 12 to <18 Years of Age With Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Plecanatide|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Comparing SAF-189s With Crizotinib In First Line ALK-Positive Advanced and Metastatic NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer|ALK-positive|SAF-189s
Interventions: OTHER: Drug: Foritinib Succinate|OTHER: Drug: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Status: COMPLETED
Conditions: Agitation in Patients With Dementia of the Alzheimer's Type
Interventions: DRUG: Placebo|DRUG: AVP-786
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copeptin After a Subcutaneous Stimulation With Glucagon in Adults
Status: COMPLETED
Conditions: Diabetes Insipidus
Interventions: DIAGNOSTIC_TEST: Glucagon|DIAGNOSTIC_TEST: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Efficacy of Artemisinin Combination Therapy in Kenya
Status: UNKNOWN
Conditions: Malaria
Interventions: DRUG: Artemether lumefantrine|DRUG: Dihydroartemisinin piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Balloon Catheter Versus Propess for Labour Induction
Status: UNKNOWN
Conditions: Childbirth Problems|Labor Complication
Interventions: DEVICE: Cook cervical balloon|DRUG: Prostin E2 Vaginal Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Sleep and Meal Timing on Food Intake Regulation
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type II|Cardiovascular Disease
Interventions: BEHAVIORAL: Normal Sleep/ Normal Meal|BEHAVIORAL: Normal Sleep/ Late Meal|BEHAVIORAL: Late Sleep/ Normal Meal|BEHAVIORAL: Late Sleep/ Late Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: D-Serine Treatment For Tardive Dyskinesia
Status: UNKNOWN
Conditions: Schizophrenia and Schizoaffective Disorder|Tardive Dyskinesia
Interventions: DIETARY_SUPPLEMENT: D-serine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy Using HyperArc in Treating Patients With Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Recurrent Head and Neck Carcinoma
Interventions: OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Dopamine Transporter Occupancy in the Healthy Adult Brain With Toludivenlafaxine Hydrochloride Extended-Release Tablets Using 11C-CFT Positron Emission Tomography (PET)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Toludivenlafaxine hydrochloride sustained-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Building Electronic Tools To Enhance and Reinforce CArdiovascular REcommendations - Heart Failure (BETTER CARE-HF)
Status: COMPLETED
Conditions: Heart Failure|Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: Best Practice Alert (BPA)|OTHER: In-Basket Message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sonography-guided Pericapsular Never Group Block for Hip Arthroplasty
Status: UNKNOWN
Conditions: Arthroplasty|Nerve Block|Analgesia
Interventions: PROCEDURE: pericapsular nerve group block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on Hypoglycaemia Awareness of Real Time CGM and Intermittent Continuous Glucose Data
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus With Hypoglycemia|Impaired Awareness of Hypoglycemia|Type1diabetes
Interventions: DEVICE: Dexcom G5 Continuous Glucose Monitor|DEVICE: Abbott Freestyle Libre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2090314 in Patients With Advanced or Metastatic Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: LY2090314|DRUG: pemetrexed|DRUG: Carboplatin|OTHER: ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calibration of MR and PET-MR Imaging Protocols at RIC
Status: WITHDRAWN
Conditions: Cancer|Coronary Artery Disease
Interventions: OTHER: PET-MR imaging on Biograph mMR scanner|OTHER: MR-only imaging on Biograph mMR scanner|OTHER: MR imaging on the Siemens Vida 3T MR scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bringing Optimised COVID-19 Vaccine Schedules To ImmunoCompromised Populations (BOOST-IC): an Adaptive Randomised Controlled Clinical Trial
Status: RECRUITING
Conditions: HIV|Organ Transplantation|Lymphoma, Non-Hodgkin|Chronic Lymphocytic Leukemia|Multiple Myeloma|COVID-19 Vaccines
Interventions: BIOLOGICAL: Pfizer Bivalent COVID-19 Vaccine|BIOLOGICAL: Moderna Bivalent mRNA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years
Status: RECRUITING
Conditions: Nephrotic Syndrome in Children
Interventions: DRUG: ACEI, SGLT-2i
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Alone or in Combination With Other Chemotherapy Drugs in Treating Patients With Metastatic Cancer of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: cisplatin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HFCWO in Hospitalized Asthmatic Children
Status: COMPLETED
Conditions: Bronchial Asthma|Asthma|Status Asthmaticus
Interventions: DEVICE: VEST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outcome of Post Burn Flexion Contracture Release Under Tourniquet Verses Tumescent Technique in Children
Status: UNKNOWN
Conditions: Hand Burns|Flexion Contracture
Interventions: PROCEDURE: post burn flexion contractures release under tourniquet control|PROCEDURE: post burn flexion contractures release using tumescent solution|PROCEDURE: Contracture release and application of FTSG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Arthroscopy in Treatment of Acute Pediatric Septic Hip Infection
Status: NOT_YET_RECRUITING
Conditions: Acute Pediatric Septic Hip Infection
Interventions: PROCEDURE: Arthroscopic management of acute pediatric septic hip infecion|PROCEDURE: Open debridement of acute pediatric septic hip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness on SDF Solution and PVP-I Combined NaF Varnish in Preventing Root Caries in Elders
Status: UNKNOWN
Conditions: Root Caries
Interventions: DEVICE: PVP-I solution combined with NaF varnish|DEVICE: SDF solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Brave Initiative: Bringing Rehabilitation to American Veterans in an Enriched Environment
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Constraint-Induced Movement Therapy (CIMT)|BEHAVIORAL: Lakeshore Enriched Fitness Training (LEFT)|BEHAVIORAL: standard Transfer Package (sTP)|BEHAVIORAL: enhanced Transfer Package (eTP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine Plus Nivolumab Following Reduced-intensity Allogeneic PBSC Transplantation for Patients With AML and High-risk Myelodysplasia
Status: WITHDRAWN
Conditions: Aml|AML, Adult
Interventions: DRUG: Nivolumab|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients With Non-resectable Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreas Cancer|Non-Resectable Pancreas Carcinoma
Interventions: DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis
Status: ENROLLING_BY_INVITATION
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome|Relapsing Remitting Multiple Sclerosis|Progressive Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: Eye tracking|DIAGNOSTIC_TEST: Microperimetry|DIAGNOSTIC_TEST: Optical coherence tomography (OCT)|DIAGNOSTIC_TEST: Visual processing speed test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Properties of Carrot Juice in Patients With High-Risk Colorectal Polyps
Status: RECRUITING
Conditions: Colorectal Cancer Prevention
Interventions: DIETARY_SUPPLEMENT: Carrot juice from Yellowstone carrots cultivars|DIETARY_SUPPLEMENT: Placebo juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Satisfaction of Patients With Trans-Arterial Radial Access: Quality of Life in Uterine Fibroid Embolization Trial
Status: COMPLETED
Conditions: Uterine Fibroid
Interventions: PROCEDURE: Arterial access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors
Status: COMPLETED
Conditions: Cervical Carcinoma|Dyspareunia|Endometrial Carcinoma|Ovarian Carcinoma|Vaginal Carcinoma|Vaginal Dryness|Vulvar Carcinoma
Interventions: PROCEDURE: Laser Therapy|OTHER: Questionnaire Administration|PROCEDURE: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-Protein Diet With Low-Protein Foods Versus a LPD Without LP Foods in Patients With Chronic Kidney Disease (CKD)
Status: RECRUITING
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5
Interventions: OTHER: Consumption of FLAVIS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BMP-2 and ALP Levels Following Laser Therapy With Scaling and Root Planing in Periodontitis- RCT.
Status: UNKNOWN
Conditions: Periodontitis, Laser
Interventions: DEVICE: SRP+Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPIRIT V: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System in the Treatment of Patients With de Novo Coronary Artery Lesions (Diabetic Sub-Study)
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: TAXUS® Liberté™|DEVICE: XIENCE V® EECSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Voltaren Emulgel 2% Acute Ankle Sprain Non Inferiority Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac diethylamine 2.32% gel|DRUG: Diclofenac diethylamine 1.16% gel|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Veteran Access to Integrated Management of Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Low Back Pain|Veterans Family
Interventions: BEHAVIORAL: Pain modulation with physical pain treatment|BEHAVIORAL: Telephone delivered self-management counseling for increasing physical activity|BEHAVIORAL: Telephone delivered behavioral treatment for participants with high risk for continued disability|BEHAVIORAL: Patient preference treatment protocol|BEHAVIORAL: Nonpharmacological guideline adherent treatment protocol|BEHAVIORAL: Facilitated referrals to existing VA or non-VA pain management resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Individual Therapy for Patients With Wilson's Disease
Status: RECRUITING
Conditions: Wilson's Disease
Interventions: DRUG: DMPS|DRUG: Penicillamine|DRUG: DMSA|DRUG: Zinc gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen
Status: COMPLETED
Conditions: High Bleeding Risk|Coronary Artery Disease|PCI
Interventions: DRUG: Aspirin|DRUG: P2Y12 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Concurrent Chemoradiotherapy or Radiation Therapy in Treating Patients With Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive Stage Small Cell Lung Carcinoma|Limited Stage Small Cell Lung Carcinoma|Neuroendocrine Neoplasm
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Etoposide|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Study of Intravenous OTS167 in Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Advanced Myelodysplastic Syndromes, Advanced Myeloproliferative Neoplastic Disorders, or Advanced Chronic Myelogenous Leukemia
Status: TERMINATED
Conditions: AML|Advanced MDS|ALL|Advanced CML|Advanced MPNs
Interventions: DRUG: OTS167IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts
Status: COMPLETED
Conditions: Cutaneous Common Warts
Interventions: DRUG: CLS006|DRUG: CLS006 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Function Changes During Swallowing in Patients With Dysphagia in Lateral Medullary Syndrome
Status: RECRUITING
Conditions: Deglutition Disorders|Lateral Medullary Syndrome
Interventions: OTHER: Functional near-infrared spectroscopy (fNIRS) detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness of the Calhoun Vision Light Adjustable Intraocular Lens (LAL)
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: Lens implantation +1.00 D postop target|DEVICE: Lens implantation -1.00 D postop target|DEVICE: Lens implantation 0.00 D postop target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: liposomal bupivacaine|DRUG: bupivacaine HCl|DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balanced Salt Solution VS. Normal Saline Solution in Septic Shock
Status: COMPLETED
Conditions: Shock, Septic|Sepsis
Interventions: DRUG: Ringer acetate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms|Colorectal Neoplasms Malignant|Colorectal Neoplasms, Benign|Colorectal Cancer|Colorectal Polyp|Colorectal Adenoma|Colorectal Adenocarcinoma
Interventions: PROCEDURE: Robotic right hemicolectomy|PROCEDURE: Laparoscopic right hemicolectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection
Status: COMPLETED
Conditions: Wound Infection or Endometritis Post Cesarean Section
Interventions: PROCEDURE: supplemental perioperative oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RD06-04 in Patients With Active Autoimmune Diseases
Status: NOT_YET_RECRUITING
Conditions: SLE (Systemic Lupus)|Sclerosis|ANCA Associated Vasculitis|IIM|SS|MS|NMO Spectrum Disorder|MG
Interventions: DRUG: RD06-04 cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tart Cherry Juice on the Body
Status: COMPLETED
Conditions: Cardiovascular Risk Factors|Age-Related Cognitive Decline
Interventions: OTHER: Tart cherry juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mobile-based Positive Psychological Support for Smoking Cessation Via "Quit to Win" Contest 2021 (QTW 2021)
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: AWARD advice|OTHER: Brief leaflet on health warning and smoking cessation|OTHER: Referral card|OTHER: Self-help smoking cessation booklet|BEHAVIORAL: Positive psychological support through 3-people group chat using instant messaging apps|BEHAVIORAL: E-messages via SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing Sarcoma
Interventions: DRUG: niraparib|DRUG: Temozolomide|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer
Status: RECRUITING
Conditions: Pharmacokinetics of Zolbetuximab|Gastric Cancer|Gastro-esophageal Junction (GEJ) Cancer|Pharmacokinetics of Oxaliplatin|Pharmacokinetics of Fluorouracil Bolus (5-FU)
Interventions: DRUG: zolbetuximab|DRUG: oxaliplatin|DRUG: leucovorin|DRUG: fluorouracil|DRUG: Pembrolizumab|DRUG: folinic acid|DRUG: nivolumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Dose for Postoperative Nausea and Vomiting Prophylaxis in Obese Patients
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone 4 mg IV-control|DRUG: Dexamethasone 4 mg IV|DRUG: Dexamethasone 8 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gender Dependent Difference in Lipemia After 6 x OFTT in Young Healthy Subjects
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Six different types of fat in a meal in random order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preparing Surrogates of Dementia Patients Through an Advance Care Planning Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Dementia
Interventions: OTHER: Nurse-facilitated advance care planning intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatosis
Status: UNKNOWN
Conditions: Human Immunodeficiency Virus|Acquired Immune Deficiency Syndrome Virus|Liver Diseases|Liver Cirrhosis|Fibrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p