pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations
Status: RECRUITING
Conditions: Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF)|Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene|Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in Botswana
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: DRUG: Isoniazid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Clinical Effect of Pregabalin on Neuropathic Pain in Non Central Sensitized Patients After Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Pregabalin 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Imaging Markers for Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Cimzia|DEVICE: Magnetic Resonance Imaging (MRI)|DEVICE: High-resolution peripheral quantitative computed tomography (HR-pQCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Cognitive/Functional Effects|Colorectal Cancer|Neurotoxicity
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Antidepressant Effects of ATP and Phosphocreatine
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: ATP|DRUG: Phosphocreatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Evaluate the Hybrid-Logic Closed Loop System in Type 1 Diabetes The DREAMED Trail
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: HLCL- Hybrid Logic Closed Loop System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IFM 2005-01: Velcade/Dexamethasone Versus Vincristine/Adriamycin (Doxorubicin)/Dexamethasone (VAD) for the Treatment of Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Liver Disease
Interventions: DRUG: Metformin|DIETARY_SUPPLEMENT: Siliphos+ Selenium - Methionine + Alpha Lipoic Acid|DIETARY_SUPPLEMENT: Siliphos+ Selenium - Methionine + Alpha Lipoic Acid|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preventing Postpartum Relapse to Smoking Using Yoga and Cognitive Behavioral Therapy: A Randomized Pilot Study
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Yoga and Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fine Particle pMDI Formoterol/Beclomethasone in Asthmatics With and Without Spacer: Comparative Efficacy Evaluation
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Spacer|DEVICE: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow-up Registry of Individuals Treated in A Gilead-Sponsored Trial in Individuals With Chronic Hepatitis B Infection
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: GS-4774|DRUG: GS-9620|DRUG: Tenofovir disoproxil fumarate (TDF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Study of Moderate-dose Hypofractionated RT Combined With Tislelizumab for HCC With Diffuse Tumor Thrombosis
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Radiotherapy|Tislelizumab|Tumor Thrombosis
Interventions: RADIATION: Moderate-dose Hypofractionated Intensity-modulated Radiotherapy|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Subtle Vibration to Improve Walking Ability by Lower Limb Amputees
Status: COMPLETED
Conditions: Amputation|Diabetes Complications
Interventions: DEVICE: Custom prosthetic socket with mechanical vibrators (stochastic resonance)|DEVICE: Conventional prosthetic socket (current clinical practice)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Different Regimens of Bemiparin as a Thromboprophylaxis in Morbidly Obese Surgical Patients
Status: RECRUITING
Conditions: Morbid Obesity
Interventions: DRUG: Bemiparin 3500|DRUG: Bemiparin 5000 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Micropulse Transscleral Diode Laser Cyclophotocoagulation (MP-TSCPC) as a Treatment Modality for Glaucoma Patients
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Micropulse transscleral cyclophotocoagulation (MP-TSCPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Procedures in the Treatment of Severe Acne Scars
Status: NOT_YET_RECRUITING
Conditions: Atrophic Acne Scar
Interventions: PROCEDURE: Scar subcision|PROCEDURE: Platelet rich plasma injection|PROCEDURE: Polydioxanone mono threads insertion|DEVICE: Fractional carbon dioxide laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Hemodynamics in Heart Failure Patients by Intracardiac Impedance Measurement
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Intracardiac Impedance Measurement Algorithm (integrated in CRT-D device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention Atrial Fibrillation by BOTulinum Toxin Injections (BOTAF)
Status: RECRUITING
Conditions: Cardiac Surgery
Interventions: DRUG: Botulinum Toxin Type A Injection [Xeomin]|OTHER: Drug placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Water From Bottles to Establish Strong Teeth
Status: RECRUITING
Conditions: Dental Caries in Children
Interventions: OTHER: Fluoridated bottled drinking water|OTHER: Non-fluoridated drinking water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cosopt Versus Xalacom
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: dorzolamide 2%/timolol maleate 0.5% fixed combination|DRUG: latanoprost 0.005%/timolol maleate 0.5% fixed combination|DRUG: timolol maleate 0.5%|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Genicular Nerve Block Versus IPACK Block for Knee Arthroscopic Surgery
Status: RECRUITING
Conditions: Genicular Nerve Block
Interventions: OTHER: popliteal artery and the capsule of the posterior knee (IPACK) block|OTHER: genicular nerves block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: How To Prevent Ventilator-Related Lung Damage in Intraoperative Mechanical Ventilation? Pcv or Vcv ?
Status: COMPLETED
Conditions: Ventilator-Induced Lung Injury|Ventilator Lung|Mechanical Ventilation Complication|Postoperative Complications
Interventions: PROCEDURE: Position/Ventilation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Status: RECRUITING
Conditions: Gait Apraxia|Mild Cognitive Impairment|Subjective Cognitive Impairment|Cerebral Atrophy|Alzheimer Disease|Dementia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing G-CSF Mobilized Peripheral Blood and G-CSF Stimulated Bone Marrow in Patients Undergoing Matched Sibling Transplantation
Status: COMPLETED
Conditions: Transplantation for Hematologic Malignancies
Interventions: PROCEDURE: G-PB Transplant|PROCEDURE: G-BM Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Nuedexta on Bulbar Physiology and Function in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: dextromethorphan HBr and quinidine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Dose De-escalation Study With BYL719 in Premenopausal Patients With Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Pre-menopausal Breast Cancer|PI3K Pathway Inhibition
Interventions: DRUG: alpelisib (BYL719)|DRUG: buparlisib (BKM120)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Alemtuzumab i.v.|BIOLOGICAL: Alemtuzumab s.c.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: End-Stage Renal Disease
Interventions: BEHAVIORAL: Nudge for PHPC NP Referral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Malignant Neoplasm in the Leptomeninges|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|RADIATION: Involved-Field Radiation Therapy|PROCEDURE: Lumbar Puncture|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|RADIATION: Proton Beam Craniospinal Irradiation|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tamoxifen With or Without Combination Chemotherapy in Treating Postmenopausal Women With Operable Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: fluorouracil|DRUG: methotrexate|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia
Status: COMPLETED
Conditions: Xerostomia|Head and Neck Cancer
Interventions: PROCEDURE: Bone Marrow Aspiration|DIAGNOSTIC_TEST: Ultrasound Imaging of Salivary Glands|OTHER: Salivary Assay|OTHER: Quality of Life Instruments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label, Single-Dose Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of Radiolabeled Androxal in Healthy Male Subjects After Oral Administration
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine as an Adjuvant to Bupivacaine in Bilateral PECs for Pain Control After Cardiac Surgeries
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: bilateral PECS|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Combining Zevalin With High-Dose Chemotherapy Prior to Autologous StemCell Transplant in Patients With Relapsed, Refractory, or Transformed Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Yttrium 90 Ibritumomab Tiuxetan ( Zevalin )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Treatment With BTL-899 and HPM-6000UF Devices
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Floor Disorders
Interventions: DEVICE: BTL-899; HPM-6000UF Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuronavigation Guided iTBS With Personalized Target for Depression
Status: ENROLLING_BY_INVITATION
Conditions: Depression
Interventions: COMBINATION_PRODUCT: sham iTBS combined with antidepressants|COMBINATION_PRODUCT: iTBS combined with antidepressants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JP-1366 20mg tablet|DRUG: JP-1366 20mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control
Status: COMPLETED
Conditions: Dry Mouth
Interventions: DEVICE: dry mouth rinse|OTHER: Water Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative 5% Dextrose Infusion & PONV
Status: COMPLETED
Conditions: Nausea, Postoperative
Interventions: DIETARY_SUPPLEMENT: Dextrose 5%, normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: "Efficiency of Preventive Interventions in Community Nursing to Improve Medication Adherence in Vulnerable Elderly"
Status: ACTIVE_NOT_RECRUITING
Conditions: Noncommunicable Diseases|Vulnerable Elderly
Interventions: OTHER: A set of preventive interventions to improve adherence in vulnerable elderly people
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Treatment of Oral Warts in HIV+ Patients
Status: COMPLETED
Conditions: Papillomatosis|HIV Infections
Interventions: DRUG: Interferon-alpha|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness Meditation and Stress Management After Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Mindfulness-based stress reduction|BEHAVIORAL: Expressive writing condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Craniomaxillofacial Allotransplantation
Status: RECRUITING
Conditions: Facial Injuries|Traumatic Wounds and Injuries|Craniofacial Injuries|Craniofacial Defects|Facial Transplantation|Facial Deformity
Interventions: DRUG: Bone marrow cell-based therapy & 1-drug immunosuppression.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Investigating the Efficacy, Tolerability, and Safety of Continuous Subcutaneous ND0612 Infusion Given as Adjunct Treatment to Oral Levodopa in Patients With Parkinson's Disease With Motor Fluctuations
Status: WITHDRAWN
Conditions: Parkinson's Disease
Interventions: DRUG: ND0612|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Behavioral Activation Utilization to Address Structural Racism and Discrimination and Improve HIV Outcomes in High-Risk, Substance-Using Populations
Status: NOT_YET_RECRUITING
Conditions: HIV Infections|Substance Use
Interventions: BEHAVIORAL: Peer Activate-LAI|DRUG: Cabenuva or Apretude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between OFDI and IVUS in PCI Guidance for Biolimus A9 Eluting Stent Implantation
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: OFDI|DEVICE: IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
Status: COMPLETED
Conditions: Dentin Hypersensitivity
Interventions: OTHER: Teethmate Desensitizer|OTHER: Gluma Desensitizer|OTHER: Hybrid Bond
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Parent-Mediated Intervention on Restricted and Repetitive Behaviors in Children With ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Online-delivered Group-based Parent Mediated Intervention for Young Children with ASD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Pressure Treatment of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Auto AFlex|DEVICE: Auto CPAP|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alpha-2b Monotherapy Versus Combination With Entecavir in HBeAg-negative Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: PEG-IFN and entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants
Status: TERMINATED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Indomethacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PAH Subjects With LTOT Use That Have Demonstrated Improved Exercise Tolerance With the Use of Inhaled Nitric
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Placebo|DRUG: iNO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Light Exposure in Pediatric Brain Tumor Survivors
Status: RECRUITING
Conditions: Brain Tumor
Interventions: BEHAVIORAL: Bright Light Exposure|BEHAVIORAL: Dim Light Exposure|OTHER: Cognitive Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Effectiveness Study of JUVÉDERM VOLBELLA® XC Injectable Gel for Lip and Perioral Enhancement
Status: COMPLETED
Conditions: Subjects Desiring Lip Augmentation
Interventions: DEVICE: JUVEDERM VOLBELLA® XC|DEVICE: Restylane-L®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MANP in African Americans With Hypertension
Status: WITHDRAWN
Conditions: Hypertension, Resistant to Conventional Therapy
Interventions: DRUG: Placebo - 1st Cycle|DRUG: MANP - 1st Cycle|DRUG: MANP - 2nd Cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.
Status: UNKNOWN
Conditions: Osteosarcoma, Advanced
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP.
Status: RECRUITING
Conditions: Asthma|Nasal Polyps|Sinusitis Chronic
Interventions: DRUG: Mepolizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influenza Vaccine Post Allogeneic Transplant
Status: TERMINATED
Conditions: Hematopoietic Stem Cell Transplant|Hematologic Malignancy
Interventions: BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Single-Dose, Pharmacokinetic/Pharmacodynamic (PK/PD), & Safety Study of BIIB017 in Participants With Renal Impairment & Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Renal Insufficiency
Interventions: DRUG: BIIB017(peginterferon beta-1a)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inhibiting Dietary Iron Absorption in Subjects With Hereditary Hemochromatosis by a Natural Polyphenol Supplement
Status: COMPLETED
Conditions: Iron Metabolism Disorders|Iron Overload|Polyphenols
Interventions: DIETARY_SUPPLEMENT: meal matrix & NPPS|DIETARY_SUPPLEMENT: meal matrix & CS|DIETARY_SUPPLEMENT: no-matrix & NPPS|DIETARY_SUPPLEMENT: no-matrix & CS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Lymphedema in Axillary Lymph Node Dissection
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphedema|Breast Cancer|Melanoma
Interventions: PROCEDURE: ALND with ARM +/- LVB|PROCEDURE: ALND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study of Intranasal RX0041-002 in Hepatic-Impaired Individuals and Subjects With Normal Hepatic Function
Status: COMPLETED
Conditions: Analgesic Allergy
Interventions: DRUG: RX0041-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Pain
Interventions: DRUG: Midazolam|OTHER: Course intervention - a professional development course for caregivers.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hoat Huyet Nhat Nhat Versus Tanakan for Treatment of Symptoms Related to the Insufficient Blood Supply to the Brain
Status: COMPLETED
Conditions: Insufficient Blood Supply to the Brain
Interventions: DRUG: Hoat Huyet Nhat Nhat|DRUG: Tanakan 40mg
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Short Term Low Dose Corticosteroids for Management of Post covid19 Pulmonary Fibrosis
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: 20 Mg Prednisone for 14 days|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ASKP1240 After a Single Intravenous Dose at Escalating Dose Levels in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics of ASKP1240|Healthy Volunteers
Interventions: DRUG: ASP1240|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Immunogenicity and Safety of a Trivalent Inactivated Influenza Vaccine, Formulation 2012-2013, in Non-Elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine (split virion, inactivated)|BIOLOGICAL: AdimFlu-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Iclepertin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracardiac CD133+ Cells in Patients With No-option Resistant Angina
Status: COMPLETED
Conditions: Stable Angina
Interventions: BIOLOGICAL: intramyocardial injection (electromechanical mapping based)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0820, Adenoma and Second Primary Prevention Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Eflornithine placebo & sulindac placebo|DRUG: eflornithine & sulindac placebo|DRUG: Eflornithine placebo & sulindac|DRUG: Eflornithine plus sulindac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Randomisation of an Anti-fibrinolytic in Symptomatic Mild Head Injury in Older Adults
Status: RECRUITING
Conditions: Traumatic Brain Injury
Interventions: DRUG: Tranexamic Acid 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).
Status: COMPLETED
Conditions: Critical Limb Ischemia (CLI)
Interventions: OTHER: Intraarterial Infusion of Autologous Bone Marrow Mononuclear Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality Improvement Intervention in Colonoscopy Using Artificial Intelligence
Status: COMPLETED
Conditions: Quality Control|Artificial Intelligence|Colonoscopy
Interventions: OTHER: quality improvement intervention using artificial intelligence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: What Embryoselection for What Chance of Success ? EmbryoSelect Study
Status: RECRUITING
Conditions: Infertility
Interventions: OTHER: Embryo culture in time lapse technology (TLT)|OTHER: Embryo culture in conventional incubator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intraoperative Hypocapnia in PROVHILO and PROBESE
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Surgery|Pulmonary Complication|Intraoperative Complications|Postoperative Complications
Interventions: BEHAVIORAL: intraoperative mechanical ventilation with hypocapnia (etCO2 < 35 mm Hg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Study to Investigate Effect of Rifampin and Itraconazole on the Pharmacokinetics of BGB-3111 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers: Asian, Non-Asian
Interventions: DRUG: BGB-3111 (Arm A)|DRUG: Rifampin|DRUG: BGB-3111 (Arm B)|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: PROCEDURE: High Frequency Oscillatory Ventilation-Hi|PROCEDURE: High Frequency Oscillatory Ventilation-Lo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa
Status: RECRUITING
Conditions: Hypophosphatasia
Interventions: DRUG: ALXN1850|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diuretic Vascular Filling in the Initial Management of Acute PE With Right Ventricular Dysfunction Normotensive
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DRUG: Furosemide|DRUG: NaCl 9% isotonic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Losartan in Bicuspid Aortic Valve Patients
Status: TERMINATED
Conditions: Bicuspid Aortic Valve|Thoracic Aortic Aneurysm
Interventions: DRUG: Cozaar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Risk|Acute Myocardial Infarction (AMI)
Interventions: DRUG: Ziltivekimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Short Course Radiotherapy With Envafolimab, Endostatin and SOX Regimen in Locally Advanced Gastric
Status: NOT_YET_RECRUITING
Conditions: Gastric/Gastroesophageal Junction Adenocarcinoma|Radiotherapy|Immunotherapy
Interventions: DRUG: Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Apatinib and MASCT in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors|Excluding T Cell Lymphoma
Interventions: DRUG: Apatinib|BIOLOGICAL: MASCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Ovarian Stimulation Followed by Timed Intercourse or Intrauterine Insemination in Infertile PCOS Patients
Status: SUSPENDED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: highly purified urinary FSH|BEHAVIORAL: timed intercourses, intrauterine insemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NEO-201 in Solid Tumors Expansion Cohorts
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Cervical Cancer|Uterine Cancer
Interventions: DRUG: NEO-201 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Cognitive Behavior Therapy Targeting Anxiety Disorders
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms
Interventions: BEHAVIORAL: Maya mobile app|BEHAVIORAL: Social Support|BEHAVIORAL: Gain Framed|BEHAVIORAL: Loss Framed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANG1005 in Leptomeningeal Disease From Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Leptomeningeal Carcinomatosis|Leptomeningeal Metastases|Brain Metastases|HER2-negative Breast Cancer
Interventions: DRUG: ANG1005|DRUG: Physician's Best Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Identify and Measure the Values and Palliative Care Pref. of Hindu Patients and Their Caregivers
Status: WITHDRAWN
Conditions: Neoplasms
Interventions: OTHER: Semi-structured interview|OTHER: Developed survey completion|OTHER: Systems of Belief Inventory (SBI-15R)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Live
Status: TERMINATED
Conditions: Hypertension, Portal
Interventions: DRUG: Avenciguat (BI 685509)|DRUG: Placebo matching Avenciguat (BI 685509)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Autoimmune Hemolytic Anemia|Systemic Lupus Erythematosus
Interventions: DRUG: Mycophenolate Mofetil 500mg|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Motor Imagery Training on Ataxic Children After Medulloblastoma Resection
Status: COMPLETED
Conditions: Cerebellar Ataxia
Interventions: OTHER: motor imaginary training|OTHER: physical thertapy training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy
Status: COMPLETED
Conditions: IgA Patients|Hydroxychloroquine
Interventions: DRUG: Hydroxychloroquine Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fenretinide Lym-X-Sorb™ in Treating Patients With Recurrent or Resistant Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fenretinide lipid matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Circumferential Spread of Anesthetic and Success in Sciatic Nerve Blockade
Status: COMPLETED
Conditions: Sciatic Nerve Blockade for Foot/Ankle Surgery
Interventions: PROCEDURE: Circumferential spread of local anesthetic|PROCEDURE: Non-circumferential spread of local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Versus Lamotrigine in Bipolar Disorder, Type II
Status: RECRUITING
Conditions: Bipolar II Disorder
Interventions: DRUG: Lithium Carbonate|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Ethanol Ablation(TEA) for Unresectable Hepatocellular Carcinoma(HCC)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TEA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telemedicine Interventions for Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: BEHAVIORAL: Physical activity|BEHAVIORAL: Diet|BEHAVIORAL: Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Synchronized Transcranial Magnetic Stimulation for PTSD
Status: COMPLETED
Conditions: PTSD|Depression
Interventions: DEVICE: NEST-1|DEVICE: SHAM|DEVICE: NEST-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study
Status: RECRUITING
Conditions: Postoperative Sore Throat
Interventions: DRUG: Topical dexamethasone|DRUG: 10% lidocaine was sprayed over the tube for the second group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Implementing a Multimodal RCT Intervention to Improve the Transition of Patients With Crohn's Disease From Pediatric to Adult Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Adolescent Development|Transition|Mental Health Wellness 1
Interventions: BEHAVIORAL: Multimodal intervention consisting of four core components|BEHAVIORAL: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on Opioid-free Anesthesia Protocol With S-ketamine and Propofol
Status: UNKNOWN
Conditions: Opioid Use, Unspecified|S-ketamine
Interventions: DRUG: S-ketamine|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating Point-of-care Diagnostics for Sexually Transmitted Infections and Antimicrobial Resistance in Primary Care in Zimbabwe
Status: ACTIVE_NOT_RECRUITING
Conditions: Sexually Transmitted Infection|Chlamydia|Gonorrhea|Trichomoniasis|Syphilis|Hepatitis B|HIV Infections|Pregnancy|Sexually Transmitted Diseases
Interventions: DIAGNOSTIC_TEST: Point-of-care STI testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ruxolitinib and Chidamide for Acute T Cell Lymphoblast Leukemia/ Lymphoblastic Lymphoma
Status: RECRUITING
Conditions: Peripheral Blood Stem Cell Transplantation
Interventions: DRUG: Modified By/Cy conditioning regimen intensified by Ruxolitinib and Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of FLOMAX® Versus Placebo in Female Patients With Lower Urinary Tract Symptoms (LUTS) With a Significant Component of Voiding Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: tamsulosin hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke
Status: RECRUITING
Conditions: Paroxysmal Atrial Fibrillation|Cryptogenic Stroke
Interventions: DEVICE: ECG smartwatch|DEVICE: Insertable Cardiac Monitor (ICM)|DEVICE: External ECG Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Role of Aromatherapy With Lavender Oil in the Long-term Care on a Patients Behavioral Problems Associated With Dementia
Status: UNKNOWN
Conditions: Dementia|BPSD
Interventions: DRUG: Lavender Oil|DRUG: sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Sımulatıon-Based Postpartum Bleedıng Management On Mıdwıfery Students
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: OTHER: Simulation-based postpartum bleeding management training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Iloprost Effects on Gas Exchange and Pulmonary Mechanics
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|Pulmonary Hypertension
Interventions: DRUG: Iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Radiofrequency Thermo-ablation Treatments of Great Saphenous Varicose Veins (3-RF Study)
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DEVICE: Venefit|DEVICE: Radiofrequency Induced Thermal Therapy|DEVICE: Endovenous Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Cisplatin Chemotherapy With or Without High Dose Proton Pump Inhibitor in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Metastasis, Neoplasm
Interventions: DRUG: Arm C|DRUG: Arm B|DRUG: Arm A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|PROCEDURE: A baseline overnight polysomnography (oPSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bi-level Erector Spine Plane Block and Combined Pectoral I-II Block in Breast Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Analgesia
Interventions: OTHER: Ultrasound guided bi-level erector spinae plane block|OTHER: Ultrasound guided modified pectoral nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections
Status: COMPLETED
Conditions: Wrinkle
Interventions: DIETARY_SUPPLEMENT: Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRP in ACLR to Prevent PTOA
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Post-traumatic Osteoarthritis|PRP
Interventions: PROCEDURE: platelet rich plasma (PRP) injection|PROCEDURE: placebo saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Spine Surgery for Adhesions in Patients Evaluated for Efficacy and Safety of MedicurtainⓇ (Pivotal Study)
Status: COMPLETED
Conditions: Intervertebral Disc Disorder|Thoracic Intervertebral Disc Disorders|Thoracolumbar Intervertebral Disc Disorders|Lumbosacral Intervertebral Disc Disorders|Tissue Adhesion, Surgery-Induced
Interventions: DEVICE: Medicurtain®|DEVICE: GUARDIX-SG®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Mycophenolate mofetil|DRUG: Sirolimus|PROCEDURE: Allogeneic bone marrow transplant|RADIATION: Total body irradiation - 200|DRUG: Levetiracetam|BIOLOGICAL: Anti-thymocyte globulin|RADIATION: Total body irradiation - 400
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Castror Oil for Labor Induction in Women With Previous Cesarean Section
Status: COMPLETED
Conditions: Induction of Labor
Interventions: DRUG: Castor Oil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT