pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intracerebral Hemorrhage Deferoxamine Trial - iDEF Ttrial
Status: COMPLETED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Deferoxamine Mesylate|DRUG: Placebo (for Deferoxamine Mesylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of High-intensity Noninvasive Positive Pressure Ventilation in AECOPD
Status: COMPLETED
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: High-intensity NPPV|DEVICE: Low-intensity NPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Ultrasonographic Hydro-dissection With Glucose 5% on Nerve Block Efficiency
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: median nerve block|PROCEDURE: median nerve block after hydro-dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Combination Chemotherapy in Treating Patients With Peripheral T-Cell Lymphoma or Natural Killer Cell Neoplasms
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bevacizumab|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: prednisone|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calibrate Samsung's BIA to Meseaure Body Composition
Status: COMPLETED
Conditions: Body Composition|Circumference Measurements|Tissue Thickness Measurements
Interventions: OTHER: Body Measurements|OTHER: Whole Body DXA Scan|OTHER: Bioelectrical Impedance Analysis (BIA)|OTHER: Bioelectrical Impedance Analysis (BIA)|OTHER: add name here
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect and Mechanism of Respiratory Stimulant Doxapram on Facilitating Emergence
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: doxapram|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Targeted agent|DRUG: Standard of care agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery Outcome Treated by Neo-adjuvant Combination of Oxaliplatin, Irinotecan, Folinic Acid and Fluorouracil (FOLFOXIRI) Regimen in Synchronous Liver Limited Metastasis Colorectal Cancer
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer|Synchronous Neoplasm
Interventions: DRUG: Neo-adjuvant Chemotherapy FOLFOXIRI Regimen|PROCEDURE: synchronous resection surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Teres Major Muscle and Subacromial Impingement Syndrome
Status: UNKNOWN
Conditions: Trigger Points in Teres Major Muscle|Subacromial Impingement Syndrome
Interventions: DEVICE: Diacutaneous Fibrolysis|OTHER: Trigger Point Pressure Release|OTHER: Protocolized physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bisoprolol With Metoprolol Succinate Sustained-release on Heart Rate and Blood Pressure in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Bisoprolol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Cabozantinib (XL184) in Adults With Advanced Malignancies
Status: COMPLETED
Conditions: Solid Tumors|Cancer
Interventions: DRUG: Cabozantinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Teen Mom Study: A Confirmatory Pragmatic Cluster RCT
Status: NOT_YET_RECRUITING
Conditions: Sedentary Behavior|Physical Activity|Gestational Weight Gain|Arterial Pressure
Interventions: BEHAVIORAL: #BabyLetsMove|BEHAVIORAL: WIC Antenatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of COX-2 Inhibitor on Radiosensitivity in Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Celecoxib|DRUG: Nedaplatin|RADIATION: Concurrent Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Iloprost, Dynamic Hyperinflation, and Oxidative Stress in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Inhaled iloprost 5.0 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Mysimba in Patients With Weight Regain After Bariatric Surgery
Status: RECRUITING
Conditions: Obesity, Morbid|Bariatric Surgery Candidate|Medication Persistence
Interventions: DRUG: Naltrexone-Bupropion Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirbanibulin Ointment and Diclofenac Sodium Gel for the Treatment of Adult Participants With Actinic Keratosis on the Face or Scalp
Status: RECRUITING
Conditions: Keratosis, Actinic
Interventions: DRUG: Tirbanibulin (Klisyri®) 10 mg/g ointment|DRUG: Diclofenac Sodium 3% Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAT-8015 in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Non-Hodgkin's Lymphoma
Interventions: DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)|DRUG: CAT-8015 (Moxetumomab Pasudotox)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin C for Iron Supplementation During Pregnancy With Risk of Anemia
Status: RECRUITING
Conditions: Vitamin C Anemia|Pregnancy Anemia
Interventions: DRUG: Vitamin C 500 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Topical Application of BMX-010 in Subjects With Atopic Dermatitis and Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis|Atopic Dermatitis
Interventions: DRUG: BMX-010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Intraoperative Visualization With Cytalux in Children
Status: RECRUITING
Conditions: Osteosarcoma|Pulmonary Metastasis|Fluorescence|Metastatic Sarcoma|Pediatrics
Interventions: DRUG: Cytalux
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: rFVIIa in ICH in Patients Treated With Anticoagulants or Anti-Platelets
Status: UNKNOWN
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: rFVIIa + (vit K in AO patients)|DRUG: FFP or aPCC+ vit K in AO treated patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effect-site Concentration of Remifentanil for Smooth Removal of the Double-lumen Endotracheal Tube
Status: COMPLETED
Conditions: Remifentanil Concentration for Smooth Emergence
Interventions: DRUG: Remifentanil titration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Behavioral Intervention on Interdialytic Weight Gain in Patients Undergoing Hemodialysis
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: BEHAVIORAL: Technology-supported behavioral intervention (text message)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab
Status: RECRUITING
Conditions: Cancer|Tumor, Solid|Advanced Solid Tumor|Metastatic Cancer|Locally Advanced Solid Tumor
Interventions: DRUG: NTX-1088|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examination of the Effect of Counselling and Follow-up After Breast Cancer Awareness Education
Status: COMPLETED
Conditions: Breast Cancer|Nurse|Education|Counselling|Follow-up
Interventions: OTHER: Reminder message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Ultra-sound Guided Radiofrequency Ablation in the Management of Head and Neck Neoplasia.
Status: WITHDRAWN
Conditions: Head and Neck Neoplasia
Interventions: PROCEDURE: Ultra-sound guided radio-frequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: RECRUITING
Conditions: Solid Cancer
Interventions: DRUG: R-DXd|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Topotecan|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of the BBP-398 in Patients With Advance Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Advanced or Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: BBP-398
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of a Light Breakfast on the Safety, Tolerability, and Pharmacokinetics of Odanacatib (MK0822)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: odanacatib|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INTREPID: Investigation of TRELEGY Effectiveness: Usual Practice Design
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/UMEC/VI|DRUG: Inhaled Corticosteroid|DRUG: LAMA|DRUG: LABA|DRUG: COPD rescue medications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Blinded Study on the Effect of Saccharomyces Boulardii CNCM I-745 on Growth and Development in Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature, Diseases
Interventions: DRUG: S. boulardii|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PSMA-Targeted 18F-DCFPyL PET/MRI for the Detection of Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Prostate Carcinoma
Interventions: DRUG: Fluorine F 18 DCFPyL|DRUG: Gadobenate Dimeglumine|DRUG: Gadobutrol|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multiparametric Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Transrectal Ultrasonography Guided Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Interferon alfa-2a|DRUG: Zidovudine|DRUG: Interferon alfa-n1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary Clearance
Status: COMPLETED
Conditions: Mucociliary Clearance
Interventions: OTHER: Placebo formulated with HFA-152a propellant via pMDI|OTHER: Placebo formulated with HFA-134a propellant via pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Cirrhosis|Portal Hypertension
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|PROCEDURE: Liver Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibody and Safety Study of 6 Doses of NicVAX in Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: BIOLOGICAL: 3'-aminomethyl-Nic r-EPA Conjugate (NicVAX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transversus Abdominis Plane Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia in Pediatrics Undergoing Open Nephrectomy
Status: RECRUITING
Conditions: Transversus Abdominis Plane Block|External Oblique Intercostal Plane Block|Postoperative Analgesia|Pediatrics|Open Nephrectomy
Interventions: OTHER: External Oblique Intercostal Plane Block|OTHER: Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of N-Acetylcysteine (NAC) in Preventing COVID-19 From Progressing to Severe Disease
Status: COMPLETED
Conditions: COVID|Sars-CoV2|SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere|Oxidative Stress
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ureteral Access Sheath Use on Postoperative Pain Level in Patients Undergoing RIRS
Status: COMPLETED
Conditions: Urolithiasis
Interventions: DEVICE: RIRS with ureteral access sheath|DEVICE: RIRS without ureteral access sheath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Blood Loss and Pain in TKA With and Without Pneumatic Tourniquet, A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Total Blood Loss
Interventions: PROCEDURE: total knee arthroplasty with and without using pneumatic tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplant for Hematologic Diseases
Status: TERMINATED
Conditions: Hematologic Malignancies
Interventions: BIOLOGICAL: Campath 1H|DRUG: Fludarabine|PROCEDURE: Stem Cell Transplant|RADIATION: Total Body Irradiation (TBI)|DRUG: FK506 (Tacrolimus) or Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTNS for Female Patients Suffering From Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Overactive Bladder
Interventions: DEVICE: PTNS Treatment|DEVICE: Sham PTNS Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Translational Study of Tumor Antigen-pulsed DC Vaccine for ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: OCDC vaccine; NeoDC vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Enriched Parent-Infant Interaction on Health in Early Life
Status: NOT_YET_RECRUITING
Conditions: Parenting Intervention
Interventions: BEHAVIORAL: Singing intervention|BEHAVIORAL: Music listening intervention|BEHAVIORAL: Book reading intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate Effect of Mulligan Two Leg Rotation and Bent Leg Raise Techniques on Hamstring Tightness
Status: COMPLETED
Conditions: Low Back Pain|Hamstring Pulled
Interventions: OTHER: Mulligan two leg rotation core muscle strengthning exercises|OTHER: mulligan bent leg raise technique, core muscle strengthning exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Non-Hodgkin Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Non-Hodgkin Lymphoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stroke Rate in Patients With Blunt Cerebrovascular Injury (BCVI) Treated With Oral Acetylsalicylic Acid (ASA) 81 mg Versus ASA 325 mg (BASA).
Status: RECRUITING
Conditions: Blunt Cerebrovascular Injury
Interventions: DRUG: Aspirin 325Mg Tab, Aspirin 81Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Giving Interleukin-2 (IL-2) Plus Anti-HIV Therapy to HIV-Positive Patients With CD4 Cell Counts of at Least 350 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Safety Study of CC-92252 in Healthy Adult Subjects and Adult Subjects With Psoriasis
Status: TERMINATED
Conditions: Healthy Volunteers|Psoriasis
Interventions: DRUG: CC-92252|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Types of Aerobic Training on Peak VO2 and Ejection Fraction for Diastolic Heart Failure Patients; a Comparative Randomized Control Trial
Status: COMPLETED
Conditions: Effect of Different Types of Aerobic Training on Diastolic Heart Failure Patients
Interventions: OTHER: aerobic exercise for upper limb|OTHER: aerobic exercise for lower limb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eplerenone For the Treatment of Chronic Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib Study of LXH254-centric Combinations in NSCLC or Melanoma
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer|Melanoma
Interventions: DRUG: LXH254|DRUG: LTT462|DRUG: Trametinib|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flublok or Fluzone With Advax-CpG55.2 or AF03
Status: COMPLETED
Conditions: Influenza|Influenza Immunisation
Interventions: DRUG: AF03|BIOLOGICAL: Delta Inulin-CpG55.2|BIOLOGICAL: Influenza Virus Quadrivalent Inactivated Vaccine|BIOLOGICAL: Quadrivalent Recombinant Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Study Comparing Local Tumor Control After Post-Operative Single-Fraction or Hypofractionated Stereotactic Radiosurgery in the Treatment of Spinal Metastases
Status: COMPLETED
Conditions: Spinal Metastases
Interventions: RADIATION: single-fraction SRS|RADIATION: high-dose hypofractionated SRS|BEHAVIORAL: Quality of Life Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impostor Syndrome and Burnout in Swiss Residents and Chief Residents Anaesthesiologists
Status: ENROLLING_BY_INVITATION
Conditions: Impostor Phenomenon|Imposter Syndrome|Burnout, Professional|Burnout, Student
Interventions: DIAGNOSTIC_TEST: Clance impostor phenomenon scale|DIAGNOSTIC_TEST: Maslach Burnout Inventory for Medical Professional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Status: COMPLETED
Conditions: Spine Surgery
Interventions: DRUG: Pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer
Status: TERMINATED
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Lung Non-Small Cell Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: BEHAVIORAL: Cognitive Behavior Therapy|OTHER: Interview|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of QBKPN Site-Specific Immunomodulator in Improving Innate Immune Function & Reducing Respiratory Tract Infection in Older Adults
Status: RECRUITING
Conditions: Immune Deficiency
Interventions: BIOLOGICAL: QBKPN SSI|OTHER: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison Between Intravenous Iron Sucrose to Its Combination With Oral Iron Supplements for the Treatment of Postpartum Anemia
Status: COMPLETED
Conditions: Postpartum Anemia
Interventions: DIETARY_SUPPLEMENT: Iron sucrose 500 mg|DIETARY_SUPPLEMENT: Iron bisglycinate 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Patient Education and Rehabilitation on Quality of Life in Patients With Permanent Stomas
Status: COMPLETED
Conditions: Colostomy
Interventions: BEHAVIORAL: Patient education and rehabilitation|BEHAVIORAL: habitual patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.
Status: ACTIVE_NOT_RECRUITING
Conditions: Sjogren Syndrome
Interventions: BIOLOGICAL: Ianalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics, Immunogenicity and Safety of Escalating Doses of BMS-188667 Given as a Single Intravenous Infusion to Patients With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of DCR-PH1 in Patients With Primary Hyperoxaluria Type 1 (PH1)
Status: TERMINATED
Conditions: Primary Hyperoxaluria Type 1
Interventions: DRUG: DCR-PH1|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: DRUG: rhNGF 60 µg/ml eye drops solution|DRUG: rhNGF 180 µg/ml eye drops solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: G-CSF in Preventing Neutropenia During First-Line Treatment With Chemotherapy and Bevacizumab in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: filgrastim|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous Bone Marrow For Lower Extremity Ischemia Treating
Status: COMPLETED
Conditions: Lower Extremity Ischemia
Interventions: PROCEDURE: Bone marrow aspiration, injection of cells|PROCEDURE: Bone marrow aspiration , injection of isolated CD 133+ cells|PROCEDURE: Bone marrow aspiration, injection of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial
Status: RECRUITING
Conditions: Refractory Angina|Chronic Myocardial Ischemia
Interventions: DEVICE: CardiAMP Cell Therapy System|OTHER: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori and Body Iron in Adults
Status: WITHDRAWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: BISMUTH TETRACYCLINE METRONIDAZOLE OMEPRAZOLE|DRUG: MATCHING PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Mailed Invites of Choice of Colonoscopy or FIT vs. Mailed FIT Alone on Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: FIT Screening Strategy|OTHER: Choice Screening Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of the Contribution of Transoral Robotic-assisted Surgery Using Da Vinci Xi for Head and Neck Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DEVICE: Transoral robotic-assisted surgery with Da Vinci Xi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Peritoneal Gas Drain on Postoperative Pain for Gynaecological Cancer Patients With Minimally Invasive Surgery
Status: COMPLETED
Conditions: Gynaecologic Cancer
Interventions: PROCEDURE: Drain|PROCEDURE: Manual exsufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Dingkundan Combined With Combination Oral Contraceptives in the Treatment of PCOS
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: DingKunDan(GuangYuYuan)|DRUG: Drospirenone and Ethinylestradiol Tablets (Ⅱ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF
Status: WITHDRAWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BLD-2660|DRUG: Control: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy For Metastatic Grade 3 Poorly Differentiated NEuroendocrine Carcinoma Of GastroEnteroPancreatic And Unknown Primary
Status: RECRUITING
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: FOLFOXIRI Protocol|DRUG: Cisplatin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIMELY: a Patient-centred Lifestyle Program for Patients With Coronary Artery Disease
Status: RECRUITING
Conditions: Myocardial Infarction|Coronary Artery Disease
Interventions: OTHER: TIMELY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of N-Acetylcysteine in Acute Liver Failure (ALF)
Status: TERMINATED
Conditions: Acute Liver Failure|Fulminant Hepatic Failure
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blinatumomab and Tyrosine Kinase Inhibitor Therapy in People With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Philadelphia Chromosome-Positive
Interventions: BIOLOGICAL: Blinatumomab|DRUG: dasatinib|DRUG: dexamethasone|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Mineralocorticoid Receptors in Vascular Function
Status: COMPLETED
Conditions: Apparent Mineralocorticoid Excess (AME)
Interventions: DRUG: Glycyrrhetic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rhomboid Intercostal Plane Block on Chronic Pain Incidence and Acute Pain Scores After Mastectomy
Status: RECRUITING
Conditions: Breast Cancer|Postoperative Pain, Acute|Postoperative Pain, Chronic|Neuropathic Pain
Interventions: PROCEDURE: RIB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Ifosfamide|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Hypnosis intervention focused on the emotional dimension of the dyspnea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Decitabine Versus Azacitidine in Myelodysplastic Syndrome Patients With Low and Intermediate-1 Risk
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Decitabine|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention
Status: RECRUITING
Conditions: Critical Illness|Wounds and Injury|Disease Attributes|Pathologic Processes
Interventions: DEVICE: Automated Titration (O2matic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Argatroban Versus Lepirudin in Critically Ill Patients
Status: TERMINATED
Conditions: Heparin Induced Thrombocytopenia (HIT)
Interventions: DRUG: Argatroban|DRUG: Lepirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-time Deflectable Guidewire in Neuro-interventions Study
Status: RECRUITING
Conditions: Unruptured Cerebral Aneurysm
Interventions: DEVICE: Deflectable guidewire|DEVICE: Standard of care guidewire (different models may be used)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Observational Trial to Assess the Performance of the TEG® 6s Diagnostic System With the Citrated K, KH, RTH, FFH Cartridge
Status: COMPLETED
Conditions: Surgery
Interventions: DIAGNOSTIC_TEST: TEG 6s Citrated K, KH, RTH, FFH Cartridge|DIAGNOSTIC_TEST: Clauss Fibrinogen
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: 40 mg glatiramer acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Augmenting Effects of ABMT on CBT in Anxious Children: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive behavioral therapy for anxiety|BEHAVIORAL: Attention Bias Modification Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cesarean Rate in Parturients Without Neuraxial Analgesia
Status: COMPLETED
Conditions: Labor
Interventions: PROCEDURE: Neuraxial analgesia|PROCEDURE: Non-neuraxial analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Lower Cyclosporine Doses for Psoriasis
Status: WITHDRAWN
Conditions: Psoriasis
Interventions: DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Acceptability and Uptake of Pre-Exposure Prophylaxis (PrEP) for Adolescent Women in The Deep South
Status: WITHDRAWN
Conditions: Adolescent Behavior|HIV/AIDS|PrEP
Interventions: OTHER: Telehealth Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Combined Armeospring and CIT on Neuro-motor and Functional Recovery in Children With Unilateral CP
Status: UNKNOWN
Conditions: Cerebral Palsy|Hemiplegia|Upper Extremity Weakness
Interventions: DEVICE: ArmeoSpring/CIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Market TRUST - U.S.A. Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Symptomatic Uterine Fibroids
Interventions: PROCEDURE: Global Fibroid Ablation (GFA)|PROCEDURE: Abdominal or Laparoscopic Myomectomy|PROCEDURE: Uterine Artery Embolization (UAE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Older Patients With Cancer
Status: RECRUITING
Conditions: Chronic Myeloproliferative Disorders|Cognitive/Functional Effects|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Unspecified Adult Solid Tumor, Protocol Specific
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequential Administration of WJ-MSCs for the Treatment of GvHD Refractory to Second Line Treatment
Status: NOT_YET_RECRUITING
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: Wharton's jelly mesenchymal stem cells (WJ-MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Potential of PET/MRI in Cardiac Sarcoidosis
Status: COMPLETED
Conditions: Sarcoidosis|Cardiomyopathies
Interventions: DIAGNOSTIC_TEST: 18F-FDG-PET/MRI|DIAGNOSTIC_TEST: 18F-GE180-PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Cardiac Variability After a Vitamine D Protocol and Whole Body Vibration
Status: UNKNOWN
Conditions: Copd|Aging
Interventions: DIETARY_SUPPLEMENT: vitamine D|OTHER: whole body vibration (WBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Can Alendronate Suppress Calcification and Improve Bone Density in Chronic Peritoneal Dialysis Patients?
Status: COMPLETED
Conditions: End-Stage Renal Disease|Osteoporosis
Interventions: DRUG: alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision Support Tool for Improving the Adequacy of Anticoagulant Therapy in Non-valvular Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Anticoagulants|Clinical Decision Support Systems
Interventions: DEVICE: CDS-NVAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DEVICE: Intra-arterial Clot Retrieval with Solitaire device|GENETIC: intravenous tissue plasminogen activator (tPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Oral Paricalcitol To Treat Proteinuric Renal Disease
Status: WITHDRAWN
Conditions: Proteinuric Renal Disease
Interventions: DRUG: paricalcitol (initial dose 1 mcg orally per day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Surgical Conditions During Gynecologic Laparoscopic Surgery With Deep Neuromuscular Blockade
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: rocuronium|DRUG: sugammadex|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microfluidics Versus Gradient Centrifugation Effect on Euploidy Rates
Status: UNKNOWN
Conditions: Infertility|Recurrent Pregnancy Loss
Interventions: DEVICE: Microfluidics chamber|OTHER: Density Gradient Centrifugation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega 3 and Ischemic Stroke; Fish Oil as an Option
Status: UNKNOWN
Conditions: Ischemic Stroke|Neurological Injury|Stroke, Acute|Inflammatory Response|Permanent Injury|Neurologic Dysfunction|Neurological Disorder|Brain Ischemia|Brain Injuries
Interventions: DIETARY_SUPPLEMENT: Omega-3 fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Effect of Yoga-based Breathing Styles on the Human Brain, With a Focus on Memory
Status: RECRUITING
Conditions: Hypoventilation|Hyperventilation
Interventions: OTHER: Nose-breathing training|OTHER: Mouth-breathing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SAR442501 in Pediatric Participants With Achondroplasia
Status: RECRUITING
Conditions: Osteochondrodysplasia
Interventions: DRUG: SAR442501
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS)
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidaemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Self-Testing to Prevent Fentanyl Overdose Among Young People Who Use Drugs
Status: COMPLETED
Conditions: Accidental Overdose of Opiate
Interventions: BEHAVIORAL: Take home rapid drug test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Diuretics, Hypertension, and Arrhythmias Clinical Trial
Status: COMPLETED
Conditions: Cardiovascular Diseases|Death, Sudden, Cardiac|Heart Arrest|Heart Diseases|Hypertension
Interventions: DRUG: hydrochlorothiazide|BEHAVIORAL: diet, potassium supplementation|BEHAVIORAL: diet, magnesium supplementation|DRUG: triamterene|DRUG: chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose:
Clinical trial: Steroid Injection for Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: DRUG: Triamcinolone Acetonide|DRUG: lidocaine hydrochloride|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Study of Intranasal Ketorolac in the Treatment of Pain Secondary to Dental Impaction Surgery
Status: COMPLETED
Conditions: Pain|Dental Impaction
Interventions: DRUG: Ketorolac tromethamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory Syndrome
Status: UNKNOWN
Conditions: Severe Acute Respiratory Syndrome
Interventions: DRUG: Lopinavir / Ritonavir plus Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Adverse Pregnancy Outcomes With a Smartphone Application in Ghana
Status: COMPLETED
Conditions: Postpartum Hemorrhage|Delivery, Obstetric|Stillbirth|Infant Mortality|Midwifery
Interventions: DEVICE: Safe Delivery smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Outcomes Using Contact Force Handling During Atrial Fibrillation Ablation
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: ThermoCoolSmartTouch ablation catheter, Biosense Webster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Immunotherapy Treatment for Patients With Hypersensitivity to Olea Europaea Pollen
Status: COMPLETED
Conditions: Rhinitis or Rhinoconjunctivitis With or Without Asthma Induced by Hypersensitivity to Olea Europea Pollen
Interventions: BIOLOGICAL: Immunotherapy with modified extract of Olea europaea pollen|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT