pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder|Autism|Anxiety|Anxiety Disorders|Generalized Anxiety Disorder|Social Anxiety Disorder
Interventions: BEHAVIORAL: LUNA-Adolescent|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Study of Gemcitabine, Cisplatin, and Nab-Paclitaxel as Neoadjuvant Therapy for Resectable Oncologically High-Risk IHCC in Korea
Status: WITHDRAWN
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Gemcitabine, Cisplatin, and Nab-Paclitaxe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission
Status: COMPLETED
Conditions: Childhood Acute Lymphoblastic Leukemia in Remission
Interventions: BEHAVIORAL: Compliance Monitoring|OTHER: Laboratory Biomarker Analysis|DRUG: Mercaptopurine|DRUG: Methotrexate|OTHER: Questionnaire Administration|OTHER: Study of Socioeconomic and Demographic Variables
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly vs. Every 2 Week vs. Every 3 Week Administration of ABI-007 (Abraxane)/Bevacizumab Combination in Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms|Neoplasm Metastasis
Interventions: DRUG: ABI-007 (Abraxane)|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Pharmacokinetic Study of HUYPS-1 in Healthy Volunteers
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: HUYPS-1 one tablet|DRUG: HUYPS-1 nine tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)
Status: RECRUITING
Conditions: Immune-related Adverse Events|Advanced Solid Tumor
Interventions: DRUG: Rituximab|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Polyphenols on Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: OTHER: Polyphenols (flavon-3-ol monomers and oligomers)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptation and Pilot Testing of a Behavioral Parent Training Program for Parents of Deaf and Hard of Hearing Children
Status: COMPLETED
Conditions: Hearing Loss|Behavior Disorders|Parenting
Interventions: BEHAVIORAL: Interventionist training and supervision|BEHAVIORAL: Behavioral parent training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PK Assessment of Tacrolimus Exposure Before and After a Switch From Twice Daily Immediate-release (Prograf®) to Once-daily Prolonged Release Tacrolimus (Envarsus®)
Status: UNKNOWN
Conditions: Allograft
Interventions: DRUG: switched from Prograf® to Envarsus®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Roles of Peers and Functional Tasks in Enhancing Exercise Training for Adults With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: The roles of peers and functional tasks in enhancing exercise training for adults with COPD: a pilot randomized controlled trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared With Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: albumin interferon alfa-2b|DRUG: peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Stop Early Age-related Macular Degeneration (AMD) From Vision Loss Eternally" Study
Status: UNKNOWN
Conditions: Age-Related Macular Degeneration|Retinal Drusen
Interventions: PROCEDURE: Subthreshold Laser Photocoagulation|DRUG: intravitreal Anti-VEGF injection|DEVICE: Subthreshold Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Body Acceptance Programs for Young Men
Status: COMPLETED
Conditions: Body Image Disturbance|Eating Disorder Symptom|Dysmorphia|Eating Disorders
Interventions: BEHAVIORAL: More than Muscles (MTM)|BEHAVIORAL: Media Advocacy (MA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Evaluation of an Alternative Sizing Model in Comparison of a Conventional Sizing Model for Full Face Masks in the Treatment of OSA in Terms of Performance and Comfort
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Obstructive Sleep Apnea
Interventions: DEVICE: Alternative sizing model based trial mask|DEVICE: Prototype Full Face Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Favipiravir Combined With Tocilizumab in the Treatment of Corona Virus Disease 2019
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Favipiravir Combined With Tocilizumab|DRUG: Favipiravir|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online TP (Training Program) on SC (Social Cognition) for Schizophrenia
Status: COMPLETED
Conditions: Social Cognition
Interventions: OTHER: Cognitive Rehabilitation and Individual Placement and Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Steroids and Pain Control After Tonsillectomy
Status: RECRUITING
Conditions: Tonsillitis|Obstructive Sleep Apnea of Child
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: BIOLOGICAL: Factor XIIa antagonist monoclonal antibody|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Thoracic Manipulation in Patients With Cervical Radiculopathy
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: PROCEDURE: Thrust Manipulation - Thoracic Spine|PROCEDURE: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additional Low Voltage Area Ablation in Older Patients With Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: CPVI plus low-voltage substrate modification|PROCEDURE: CPVI alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab in Treating Patients With Persistent, Recurrent, or Metastatic Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Recurrent Cervical Carcinoma|Stage IV Cervical Cancer AJCC v6 and v7|Stage IVA Cervical Cancer AJCC v6 and v7|Stage IVB Cervical Cancer AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone in the Treatment of Psychotic-like and Deficit Symptoms of Schizotypal Personality Disorder
Status: COMPLETED
Conditions: Schizotypal Personality Disorder
Interventions: DRUG: Risperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: 6MHP|DRUG: Montanide ISA-51|DRUG: polyICLC|DRUG: CDX-1127
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: bb2121|DRUG: Daratumumab|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Bortezomib|DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Carfilzomib|DRUG: Elotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Versus Conventional Physical Therapy for Chronic Shoulder Tendinopathy
Status: COMPLETED
Conditions: Musculoskeletal Pain|Chronic Shoulder Pain|Shoulder Tendinopathy
Interventions: DEVICE: Digital rehabilitation|DEVICE: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Radiotherapy Combined With Donafenib for Neoadjuvant Treatment of Patients With HCC With Portal Vein Carcinoma Thrombosis
Status: UNKNOWN
Conditions: HCC|Chemotherapy Effect
Interventions: DRUG: Donafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing MRI to Study the Effect of Sulforaphane on Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Standard broccoli soup|DIETARY_SUPPLEMENT: Beneforte extra broccoli soup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology
Status: COMPLETED
Conditions: Diseases of Oesophagus Stomach and Duodenum
Interventions: DRUG: Dexamethasone|DRUG: Diphenhydramine|DRUG: Famotidine|DRUG: Mitomycin C|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multilevel Intervention of COVID-19 Vaccine Uptake Among Latinos
Status: ENROLLING_BY_INVITATION
Conditions: Vaccine Hesitancy
Interventions: BEHAVIORAL: Multilevel Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Genotyping Guided Individualized Treatment of Clopidogrel and Ticagrelor in ACS
Status: UNKNOWN
Conditions: CLOPIDOGREL, POOR METABOLISM of (Disorder)
Interventions: DRUG: genotyping guided therapy Ticagrelor, Clopidogrel|DRUG: standard therapy clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Exploratory Study on the Baseline Level of NAD+/NADH in Peripheral Blood Samples of Different Gender and Age Groups of Healthy Adults.
Status: NOT_YET_RECRUITING
Conditions: NAD+/NADH in Peripheral Blood Monitoring
Interventions: OTHER: Detection of NAD+/NADH concentration of Peripheral Blood Samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Controlled Ovarian Stimulation by HP-hMG for IVF / ICSI Cycles: Study on Ovarian Hyper Stimulation Syndrome in a Cohort of Women From 18 to 36 Years Old.
Status: COMPLETED
Conditions: Ovarian Hyperstimulation Syndrome (OHSS)
Interventions: OTHER: Highly purified menotropin (HP- hMG) treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Purified CD34+ Cells Versus Peripheral Blood Mononuclear Cells in Treatment of Critical Limb Ischemia
Status: UNKNOWN
Conditions: Thromboangiitis Obliterans|Arteritis|Peripheral Arterial Disease
Interventions: OTHER: autologous purified CD34+ cells|OTHER: autologous peripheral blood mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pacritinib w/ Talazoparib in Pts w/ Myeloproliferative Neoplasms Unresponsive to JAK2 Inhibition
Status: RECRUITING
Conditions: Primary Myelofibrosis|Post-polycythemia Vera Myelofibrosis|Post-essential Thrombocythemia Myelofibrosis|Chronic Myelomonocytic Leukemia|Polycythemia Vera|Essential Thrombocytosis
Interventions: DRUG: Talazoparib|DRUG: pacritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Environments in Patients Receiving Treatment for Cancer
Status: COMPLETED
Conditions: Mood Disturbances
Interventions: BEHAVIORAL: Immersive Virtual Reality (VR)|BEHAVIORAL: Guided Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics and Absolute Bioavailability of Fer-In-Sol and Triferic Administered Orally With Shohl's Solution in Healthy Volunteers
Status: COMPLETED
Conditions: Iron-refractory, Iron-deficiency Anemia (IRIDA)
Interventions: DRUG: Triferic|DRUG: Fer-In-Sol|DRUG: Shohl's solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Investigating a Delayed-Release Pancrelipase in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Pancreatic Exocrine Insufficiency
Interventions: DRUG: Pancrelipase Delayed Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Colorectal Cancer|Pancreatic Cancer|Solid Tumor|Cancer|Cancer of Pancreas|Cancer of Colon
Interventions: DRUG: HBI-2376
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-02-41
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Alcon Investigational Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease
Status: UNKNOWN
Conditions: Chronic Chagas Disease, Indeterminate
Interventions: DRUG: E1224|DRUG: Benznidazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1|Diabetes Mellitus Type 2
Interventions: DRUG: Sitagliptin (Januvia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Insulin Aspart Injection to Evaluate the Efficacy and Safety
Status: COMPLETED
Conditions: Diabetes
Interventions: BIOLOGICAL: insulin Aspart injection|BIOLOGICAL: insulin Aspart injection (NovoRapid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing P1101 to Entecavir in Patients With HBeAg(-) Hepatitis B Under Long-term Nucleos(t)Ide Analogue Therapy
Status: RECRUITING
Conditions: Chronic Hepatitis B Virus Infection
Interventions: DRUG: Ropeginterferon alfa-2b|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and Salaried Staff From a French Anti-cancer Center
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: serology and ELISPOT test|BIOLOGICAL: serology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed/Refractory Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Marginal Zone Lymphoma|B-cell Lymphoma
Interventions: DRUG: ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Andexanet Alfa in ICrH Patients Receiving an Oral FXa Inhibitor
Status: COMPLETED
Conditions: Acute Intracranial Hemorrhage
Interventions: DRUG: andexanet alfa|DRUG: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Dental Anxiety Coping Module on Children With Dental Anxiety
Status: NOT_YET_RECRUITING
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Dental Anxiety Coping Module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors
Status: UNKNOWN
Conditions: Colorectal Cancer|Ovarian Cancer|Gastric Cancer|Breast Cancer|Lung Cancer|Kidney Cancer|Melanoma
Interventions: BIOLOGICAL: Autologous or Allogeneic tumor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sequential vs. Standard Laser Treatment of Twin-twin Transfusion Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Twin Twin Transfusion Syndrome
Interventions: PROCEDURE: Sequential laser photocoagulation of communicating vessels.|PROCEDURE: Selective laser photocoagulation of communicating vessels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging of the Liver in Children 0-2 Months of Age With an Intravenous Injection of Eovist/Primovist Which is a Contrast Agent
Status: TERMINATED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadoxetate disodium (Eovist/Primovist, BAY86-4873)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nutritional Supplementation in Patients With no Signs of Malnutrition
Status: UNKNOWN
Conditions: Primary Neoplasm|Secondary Neoplasm|Abdominal Neoplasm
Interventions: DIETARY_SUPPLEMENT: Nutritional supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety and Efficacy of Vilaprisan in Japanese Subjects With Uterine Fibroids and Heavy Menstrual Bleeding
Status: TERMINATED
Conditions: Uterine Fibroids and Heavy Menstrual Bleeding
Interventions: DRUG: Vilaprisan (BAY1002670)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Digital Application for Patients With Acute Leukemia
Status: NOT_YET_RECRUITING
Conditions: Relapsed Adult Acute Myeloid Leukemia|Primary Refractory Acute Myeloid Leukemia|High Risk Acute Myeloid Leukemia
Interventions: BEHAVIORAL: DREAMLAND|BEHAVIORAL: VITAL WELLNESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, and Immunogenicity Study of a Cell-based Virosomal Influenza Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent virosomal influenza vaccine|BIOLOGICAL: Commercial vaccine 1|BIOLOGICAL: Quadrivalent virosomal influenza vaccine|BIOLOGICAL: Commercial vaccine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas
Status: UNKNOWN
Conditions: Astrocytoma|Oligodendroglioma|Oligoastrocytoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selfcare MAnagement InteRvenTion in Heart Failure II (SMART HF II)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: LifePod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Hemodynamic Interactions of TPN171H Tablets & Alcohol in Healthy Male Subjects
Status: COMPLETED
Conditions: Alcohol|Phosphodiesterase Inhibitor|Erectile Dysfunction
Interventions: DRUG: TPN171H tablet plus alcohol|OTHER: alcohol|DRUG: TPN171H tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Centanafadine Sustained-Release (CTN SR) in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: CTN SR|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Breast
Interventions: DRUG: DS-8201a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PT001 MDI Versus Atrovent Study in Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PT001 MDI|DRUG: Ipratropium Bromide HFA Inhalation Aerosol|OTHER: Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal Mask in Upper Gastrointestinal Procedures
Status: TERMINATED
Conditions: Anesthesia|Airway Device|C.Surgical Procedure; Gastrointestinal
Interventions: DEVICE: Sedation with Gastro Cuff Pilot Laryngeal Mask|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Music Listening to Lower Anxiety During ECT Treatment.
Status: COMPLETED
Conditions: Anxiety State
Interventions: OTHER: Listening to playlists with music prior to-, during and after the ECT procedure|OTHER: Listening to playlists with music prior to-, during and after the ECT procedure|OTHER: Listening to playlists with sound from nature (rain, waves) prior to-, during and after the ECT procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a 2-week Relaxing Music Intervention on Anxiety, Stress, and Gut Symptoms in Aerobic Exercisers
Status: COMPLETED
Conditions: Gastrointestinal System--Abnormalities|Anxiety|Visceral Pain
Interventions: BEHAVIORAL: Relaxing music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: BIOLOGICAL: MGTA-145|DRUG: Plerixafor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Autologous Transfusion and Recurrence-free Survival in Patients With HCC After Resection
Status: COMPLETED
Conditions: Liver Cancer
Interventions: PROCEDURE: Autotransfusion|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Different Pain Scores in Single-Port Access (SPA) Laparoscopic Hysterectomy Versus Conventional Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Uterine Myoma|Uterine Adenomyosis
Interventions: PROCEDURE: conventional laparoscopic hysterectomy|PROCEDURE: SPA laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Paracoracoid Subscapularis Plane Block to Interscalene Block for Arthroscopic Shoulder Surgery
Status: UNKNOWN
Conditions: Rotator Cuff Injury
Interventions: PROCEDURE: Interscalene Block|PROCEDURE: Paracoracoid SPB|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DNA Sequencing in Clinical Practice, Mayo Clinic Health Tapestry Study
Status: RECRUITING
Conditions: Genetic Disorder
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Diagnostic Laboratory Biomarker Analysis|OTHER: Genetic Counseling|OTHER: Questionnaire Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Add-on Study for Protocol G200802 (NCT02463032): Effect of GTx-024 on Maximal Neuromuscular Function and Lean Body Mass
Status: WITHDRAWN
Conditions: ER+ and AR+ Breast Cancer
Interventions: DRUG: GTx-024 9 or 18 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Obesity Treatment in a Safety Net Clinic: Piloting the Step by Step Program
Status: COMPLETED
Conditions: Pediatric Obesity|Overweight and Obesity
Interventions: BEHAVIORAL: Step by Step: A Family-Centered Healthy Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodialysis Vitamin D Pilot
Status: COMPLETED
Conditions: Vitamin D Deficiency|Renal Failure Chronic Requiring Hemodialysis
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventions to Prevent Adolescents With Type 1 Diabetes From Long-term Complications
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Motivational Interviewing, CBT and E-mail support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG With Entinostat and Nivolumab as Adjuvant Therapy Following Chemoradiation Therapy With or Without Surgery for Locally Advanced Esophageal Cancer
Status: WITHDRAWN
Conditions: Neoplasms|Esophageal Neoplasms|Esophagus Neoplasm|Esophagus Cancer|Neoplasms, Esophageal|Esophageal Cancer (EsC)
Interventions: DRUG: Nivolumab|DRUG: Entinostat|BIOLOGICAL: Montanide(R) ISA-51 VG Adjuvant|BIOLOGICAL: H1299 Cell Lysates
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonography For Radial Artery Diameter Measurement And Its Correlation With Allen Test
Status: UNKNOWN
Conditions: Anesthesia|Ultrasonography|Radial Artery|Catheterization
Interventions: OTHER: Allen test|OTHER: Radial artery diameter measurement by ultrasonography|OTHER: Ulnar artery doppler ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Personality Traits on Reporting Outcomes of Orthodontic Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Malocclusion
Interventions: DEVICE: active metal appliance|DEVICE: active esthetic appliance|COMBINATION_PRODUCT: retention fixed appliance|COMBINATION_PRODUCT: retention removable appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Quality of Life Induced by the Cinnamon Anti-odor Dressing in Patients With Malodorous Wounds
Status: RECRUITING
Conditions: Malodorous Wounds (Chronic, Malignant or Infected Wounds)
Interventions: OTHER: Cinnamon dressing|OTHER: Charcoal dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban (10mg) Given Once Daily in Patients Undergoing Total Hip Replacement Compared to Enoxaparin
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Small Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Etoposide|RADIATION: Thoracic radiation therapy (TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS and Cognitive Training Intervention for Chronic Smokers With Schizophrenia
Status: TERMINATED
Conditions: Transcranial Direct Current Stimulation|Smoking, Cigarette|Schizophrenia
Interventions: OTHER: Transcranial Direct Current Stimulation|BEHAVIORAL: Cognitive Remediation (CR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Phonak EduLink-System in Students With Specific Performance Deficits in Speech-in-Noise Intelligibility
Status: UNKNOWN
Conditions: Auditory Processing Disorder
Interventions: DEVICE: hearing aid, Phonak EduLink-FM System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Added Value of Metamizole to Standard Post-operative Treatment After Ambulant Surgery
Status: COMPLETED
Conditions: Analgesia|Surgery|Recovery
Interventions: DRUG: Metamizole|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy
Status: UNKNOWN
Conditions: Hepatitis, Autoimmune|Primary Biliary Cholangitis|Immunosuppression
Interventions: DRUG: Cyclosporin A|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety, Tolerability, Pharmacokinetics, and Drug-drug Interaction of Multiple Oral Doses of BAY1830839 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BAY1830839|DRUG: Placebo|DRUG: Midazolam|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nadroparin Anticoagulation for Continuous Venovenous Hemofiltration
Status: COMPLETED
Conditions: Kidney|Acute Renal Failure|Multiple Organ Failure
Interventions: PROCEDURE: CVVH 4 to 2 L/h|PROCEDURE: CVVH 2 to 4L/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concomitant Use of Gardasil (V501, Human Papillomavirus [Types 6, 11, 16, 18] Recombinant Vaccine) With Combined Diptheria, Tetanus, Pertussis and Poliomyelitis Vaccine in Adolescents (V501-024)(COMPLETED)
Status: COMPLETED
Conditions: Neoplasms, Glandular and Epithelial|Diphtheria|Tetanus|Whooping Cough|Poliomyelitis
Interventions: BIOLOGICAL: Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Current Manufacturing Facility (CMF)|BIOLOGICAL: Comparator: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant (qHPV) Vaccine from Future Manufacturing Facility (FMF)|BIOLOGICAL: Comparator: REPEVAX™ (Concomitant)|BIOLOGICAL: Comparator: REPEVAX™ (Non-Concomitant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Early Phase Study of Abraxane Combined With Phenelzine Sulfate in Patients With Metastatic or Advanced Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Nanoparticle albumin-bound paclitaxel|DRUG: Phenelzine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY86-9766 Plus Gemcitabine Phase I Study in Asian
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Refametinib (BAY86-9766)|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Personalized Auricular Vagus Nerve Stimulation in Intractable Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: DEVICE: AuriMod CT01_A|DEVICE: AuriMod CT01_B|DEVICE: AuriMod CT01_C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 64Cu/68Ga Labelled EB-ss-CPT PET/CT Scan in Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: 68Ga-EB-ss-CPT|DRUG: 64Cu-EB-ss-CPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Imatinib in Advance Liver Fibrosis Patients
Status: UNKNOWN
Conditions: Liver Fibrosis
Interventions: DRUG: Imatinib 200mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Drug Interactions When DA-8010 is Co-administered With Paroxetine or Mirabegron in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-8010 5mg|DRUG: Paroxetine 20mg|DRUG: Mirabegron 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTMS Targets Neural Circuits for Smoking Cessation
Status: RECRUITING
Conditions: Tobacco Use|Cigarette Smoking
Interventions: DEVICE: Sham rTMS|DEVICE: Active rTMS 10 Hz DLPFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder|Bipolar I Disorder|Bipolar II Disorder|Bipolar Type I Disorder|Bipolar Disorder Mild|Bipolar Disorder Moderate|Bipolar Disorder Severe
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Be Outspoken and Overcome Stigmatizing Thoughts (BOOST) Group for Early Psychosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Psychosis
Interventions: BEHAVIORAL: Self-stigma intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of Nitazoxanide in HIV-HCV Treatment Failures
Status: COMPLETED
Conditions: Hepatitis C Infection|HIV Infection
Interventions: DRUG: Nitazoxanide With Pegylated Interferon And Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-PM-PBB3 PET Study in Tauopathy Including Alzheimer's Disease, Other Dementias and Normal Controls
Status: COMPLETED
Conditions: Alzheimer's Disease|Cortical Basal Syndrome|Frontotemporal Dementia|Progressive Supranuclear Palsy|Vascular Cognitive Impairment
Interventions: DRUG: F-18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Ionizing Treatment on the Nuclear Structure of Human Spermatozoa.
Status: UNKNOWN
Conditions: Sperm Preservation|Irradiated Semen
Interventions: OTHER: Cryopreserved semen|OTHER: Acute and low irradiation|OTHER: Long and low irradiation|OTHER: Long and medium irradiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Moderate Physical Activity on Diabetic Adhesive Capsulitis: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: OTHER: Moderate Physical Activity + Conventional Physical Therapy|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Single Shot vs 24hr vs 48hr Continuous Adductor Canal Block After TKA
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Osteoarthritis|Post Operative Pain Control
Interventions: DRUG: 20ml bolus of 0.5% ropivicaine|DRUG: 0.2% Ropivicaine at 8 milliliter/hour|DRUG: 5ml bolus of 0.5% ropivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Improvement of Diabetic Neuropathic Pain by Liraglutide
Status: UNKNOWN
Conditions: Diabetic Neuropathic Pain
Interventions: DRUG: Liraglutide|DRUG: insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia
Status: RECRUITING
Conditions: Hiatal Hernia
Interventions: OTHER: Opioid Sparing Anesthesia Protocol (OSA)|OTHER: Opioid Based Anesthesia Protocol (OBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: SUCCEED - Soroka Utility for Counting Carbs Easily and Effectively for Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Carbohydrates|Insulin Sensitivity|HbA1C
Interventions: OTHER: carbohydrate counting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study to Evaluate the IBS Symptoms Improving Effect and Safety of GTB1
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DIETARY_SUPPLEMENT: GTB1|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Efpeglenatide SAR439977|DRUG: Placebo|DRUG: Background therapy: Metformin alone or in combination with SU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persona MC vs PS RCT With ROSA
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: Zimmer-Biomet Persona Medial Congruent (MC) Bearing Design|DEVICE: Zimmer-Biomet Persona Posterior-Stabilized (PS) Bearing Design
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal Isonicotinic Acid Hydrazide Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System
Status: COMPLETED
Conditions: IUCD Complication
Interventions: DRUG: INH|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ethanol Gel Versus Steroid in Refractory Lumbar Discogenic Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Discogenic Pain (Disorder)
Interventions: DEVICE: Ethanol gel|DRUG: Prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRV-3279-2a Trial in Systemic Lupus
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: PRV-3279|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Safety and Efficacy of Autologous Bone Marrow-derived Endothelial Progenitor Cells in Advanced Liver Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: OTHER: Autologous bone marrow-derived endothelial progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of The Fitting Success Rate Of Senofilcon A Soft Contact Lenses In Three Designs.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: First pair Senofilcon A contact lens|DEVICE: Second pair Senofilcon A contact lens|DEVICE: Third pair Senofilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CCTAP: Cognitive Control Training for Treatment of AUD-PTSD
Status: COMPLETED
Conditions: Alcohol Use Disorder|Post Traumatic Stress Disorder
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition and Lifestyle Behaviour Peer Support Program Among Malaysian Adults With Metabolic Syndrome (PERSUADE)
Status: UNKNOWN
Conditions: Metabolic Syndrome X|Nutritional and Metabolic Diseases|Health Behavior
Interventions: BEHAVIORAL: Peer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ability of the Probiotic Vivomixx to Improve Environmental Enteropathy in Pregnant Women: a Proof of Concept Trial in Bangladesh, Pakistan, Senegal and Zambia
Status: NOT_YET_RECRUITING
Conditions: Environmental Enteropathy
Interventions: DIETARY_SUPPLEMENT: VSL#3|DEVICE: Capscan device|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: D-cycloserine in the Management of Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Pain
Interventions: DRUG: D-cycloserine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bliss DTx Assessment During Course Care Including Port-A-Catheter Setting
Status: RECRUITING
Conditions: Cancer
Interventions: DEVICE: Pain management with BLISS DTx|OTHER: Pain Management with site standard of care sedation protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Knee Osteoarthritis With Autologous Adipose-derived Mesenchymal Stem Cells
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BIOLOGICAL: Auotologous AMSCs plus autologous PRP|BIOLOGICAL: Auotologous PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Testosterone Undecanoate in Hypogonadal Men
Status: COMPLETED
Conditions: Hypogonadism, Male
Interventions: DRUG: SOV2012-F1|DRUG: AndroGel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT