pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events
Status: RECRUITING
Conditions: Moral Injury|Functional Impairment
Interventions: BEHAVIORAL: Open pilot trial of a group therapy manual.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIg) for the Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Status: COMPLETED
Conditions: Demyelinating Diseases|Paraproteinemias
Interventions: DRUG: intravenous immunoglobulin (IVIg)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Dextromethorphan in OCD and Related Disorders
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Illness Anxiety Disorder|Body Dysmorphic Disorders|Somatic Symptom Disorder
Interventions: DRUG: Fluoxetine|DRUG: Dextromethorphan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone|DRUG: Hydroxychloroquine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Socazolimab as First-Line Treatment in Persistent, Recurrent, or Metastatic Cervical Cancer
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Socazolimab+cisplatin/carboplatin+paclitaxel+Bevacizumab|DRUG: Placebo+cisplatin/carboplatin+paclitaxel+Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Radiofrequency of 448 kHz on Pain and Function
Status: COMPLETED
Conditions: Chronic Low-back Pain|Lumbago|Low Back Pain, Recurrent
Interventions: DEVICE: 448kHz capacitive resistive monopolar radiofrequency|OTHER: Proprioceptive Neuromuscular Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medical Expulsive Therapy Post-SWL For Renal Stones
Status: COMPLETED
Conditions: Urologic Diseases|Urolithiasis|Stone, Kidney
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
Status: COMPLETED
Conditions: Alcohol Reactivity
Interventions: DRUG: varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LNP023 Compared With Rituximab in Subjects With Idiopathic Membranous Nephropathy
Status: TERMINATED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: LNP023|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FAMILY INHERITANCE, GENE-GENE AND GENE-ENVIRONMENT INTERACTIONS IN THE FIELD OF CARDIOVASCULAR AND RENAL DISEASES. Fifth Visit of the STANISLAS Cohort
Status: RECRUITING
Conditions: Cardiovascular Diseases|Cohort Studies|Genotype|Risk Factors|Nutrition
Interventions: BIOLOGICAL: Blood and urine samples|GENETIC: Blood samples|OTHER: Cardiovascular assessment|BEHAVIORAL: Dietary intake|OTHER: Anthropometric parameters|OTHER: Hemodynamic parameters|OTHER: Hemodynamic parameters|OTHER: Hemodynamic parameters|OTHER: Hemodynamic parameters|BEHAVIORAL: Assessment of compliance with antihypertensive treatments for treated participants|OTHER: Ambulatory 24 hours measurment of blood pressure|BIOLOGICAL: 24 hours urinary collection|OTHER: General questionnaires|OTHER: Women specific questionnaire|BEHAVIORAL: Women specific questionnaire|DIAGNOSTIC_TEST: NYHA dyspnea questionnaire|BEHAVIORAL: Anxiety questionnaire|BEHAVIORAL: Epworth Sleepiness Scale|OTHER: A questionnaire on the "perception of the management of cardiovascular risk factors"|BEHAVIORAL: A questionnaire on eating behaviors|BEHAVIORAL: A questionnaire on eating habits to determine consumer profiles|DIETARY_SUPPLEMENT: A questionnaire on food supplements use|OTHER: SARS-CoV-2 Infection Questionnaire|OTHER: Instantaneous expired air analysis|BIOLOGICAL: Capillary sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Avatrombopag vs. Avatrombopag Combined With rhTPO in the Treatment of SAA
Status: NOT_YET_RECRUITING
Conditions: Anemia, Aplastic
Interventions: DRUG: Avatrombopag|DRUG: Avatrombopag +rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Predictive Scale of Chronic Postsurgical Pain
Status: UNKNOWN
Conditions: Chronic Postoperative Pain
Interventions: PROCEDURE: Inguinal hernia repair|PROCEDURE: Abdominal hysterectomy|PROCEDURE: Vaginal hysterectomy|PROCEDURE: Thoracotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stem Cell and Conditioned Medium for Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cells|BIOLOGICAL: Conditioned Medium|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anesthesia Management on Optic Nerve Sheath Diameter in the Ercp Procedures
Status: UNKNOWN
Conditions: Cholangiopancreatography, Endoscopic Retrograde|Intracranial Pressure|Optic Nerve Sheath Diameter|Ketofol|Propofol
Interventions: DIAGNOSTIC_TEST: Sonographic optic nerve sheath diameter measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Trial Assessing the Outcome of Celecoxib Administration Versus Placebo Following Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Activity of Inspiratory Muscles With the Use of Positive Pressure in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Expiratory positive airway pressure (EPAP) by face mask.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Foeniculum Vulgare Ironing on Gastrointestinal Recovery After Colorectal Resection
Status: COMPLETED
Conditions: Colorectal Surgery|Foeniculum|Ileus
Interventions: DRUG: Foeniculum Vulgare Seed Ironing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone Tolerability in the Treatment of Acute Asthma in Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ora Sweet|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Midomafetamine|BEHAVIORAL: Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Effect of Vildagliptin and How the Body Changes the Blood Level of Vildagliptin in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vildagliptin (LAF237)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hernia Repair in Multiply Morbid Patients
Status: TERMINATED
Conditions: Ventral Hernia
Interventions: DEVICE: Strattice Reconstructive Tissue Matrix (Hernia Repair)|DEVICE: Proceed Surgical Mesh (Hernia repair)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantification of Hepatic Fibrosis by IVIM Sequences in 1.5T MRI
Status: UNKNOWN
Conditions: Liver Fibrosis|MRI|IVIM|Liver Biopsy
Interventions: PROCEDURE: Quantification of liver fibrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trimebutine on the Development of Adverse Events Related to the Helicobacter Pylori Eradication Medications
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Trimebutine 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Study of Uprifosbuvir (MK-3682/IDX21437) in Healthy and Hepatitis C Virus (HCV)-Infected Participants (MK-3682-001)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Uprifosbuvir|DRUG: Placebo|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early External Cephalic Version (ECV) 2 Trial
Status: COMPLETED
Conditions: Breech Presentation
Interventions: PROCEDURE: Early ECV between 34 0/7 and 35 6/7 weeks|PROCEDURE: Delayed ECV at or after 37 0/7 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)
Status: COMPLETED
Conditions: Hyperglycemia|Critical Illness
Interventions: OTHER: Intensive Insulin Therapy|OTHER: Conventional Insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)
Status: NOT_YET_RECRUITING
Conditions: Chronic Ankle Instability
Interventions: OTHER: Neurocognitive Ankle Training for Instablity to Optimize Neuromusculoskeletal outcomes (NATION)|OTHER: Evidence-Based
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: AcrySof Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of B7A BSIgG Against E. Coli Strain B7A Challenge
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: BIOLOGICAL: Anti CS6 BSIgG product (Lot PD1601105CS)|BIOLOGICAL: Anti B7A BSIgG product (Lot PD1601132ET)|BIOLOGICAL: Bovine Immunoglobin Negative Control (Lot PD161071NC)|BIOLOGICAL: B7A- CS6-expressing ETEC challenge strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Daily Facial Cleanser
Status: COMPLETED
Conditions: Skin Irritation
Interventions: OTHER: Cetaphil Daily Facial Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of Recombinant Human C1 Esterase Inhibitor in Healthy Adult Subjects
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: DRUG: Recombinant human C1 esterase inhibitor|DRUG: Placebo|DRUG: SHP623|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of SSS17 in Healthy Subjects.
Status: UNKNOWN
Conditions: Anemia in Chronic Kidney Diseases
Interventions: DRUG: SSS17|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fetal Autonomic Nervous sysTem Evaluation
Status: RECRUITING
Conditions: Pregnancy Related|Pregnancy Disease|Pregnancy Complications|Pre-Eclampsia|Gestational Diabetes|ECG Electrode Site Reaction|Fetal Growth Retardation|Fetal Complications
Interventions: DEVICE: electrocardiograph
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Bimatoprost SR|DRUG: Sham Bimatoprost SR|PROCEDURE: Selective Laser Trabeculoplasty|PROCEDURE: Sham Selective Laser Trabeculoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Planning and Informed Consent
Status: COMPLETED
Conditions: Communication|Feedback, Psychological|Health Knowledge, Attitudes, Practice|Humans|Informed Consent|Neurosurgery|Patient Compliance|Patient-Centered Care|Physician-Patient Relations|User-Computer Interface
Interventions: OTHER: 3D informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Carboplatin and Docetaxel in Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telehealth Interventions for Daily Routine Activities in Children and Adolescents With Disabilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Children With Physical Disabilities|Adolescents With Physical Disabilities
Interventions: BEHAVIORAL: Individualized intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: Photorefractive keratectomy (PRK)|DEVICE: ALLEGRETTO WAVE EYE-Q excimer laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aβ Dynamics in LLMD
Status: RECRUITING
Conditions: Alzheimer Disease|Major Depressive Disorder
Interventions: DRUG: Escitalopram Oxalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Teamwork Perceptions When Mobilizing Ventilated Neurosurgery Patients
Status: COMPLETED
Conditions: Multidisciplinary Communication
Interventions: OTHER: Nurse-led progressive mobility protocol|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: CogEcig: Cognitive Functioning and Electronic Cigarette
Status: COMPLETED
Conditions: Tobacco Abuse Smoke
Interventions: OTHER: Own Brand cigarette|OTHER: one high 2,4% nicotine|OTHER: original 7,4 mg nicotine|OTHER: nicotine free|OTHER: Ego 9mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk of Nerve Damage After Administration of Local Anesthesia
Status: RECRUITING
Conditions: Inferior Alveolar Nerve Injuries
Interventions: DRUG: 4% Articaine with 1:200,000 epinephrine|DRUG: 2% lidocaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Identify the Impact of Denosumab on the Immune System in Patients With HER2 Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DRUG: Denosumab 120 mg|DRUG: Denosumab 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Video-Enhanced Care Management for Medically Complex Veterans
Status: COMPLETED
Conditions: Multimorbidity|Cognitive Impairments
Interventions: BEHAVIORAL: Care management via videoconference|BEHAVIORAL: Care management via telephone calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of SP059 Given Subcutaneously as a Three-dose Primary and Booster Vaccination in Infants in Japan
Status: COMPLETED
Conditions: Poliomyelitis|Polio
Interventions: BIOLOGICAL: Inactive Poliovirus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Paricalcitol Capsules in Decreasing Serum Parathyroid Hormone Levels in Children Aged 10-16 With Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 3 and 4
Interventions: DRUG: Paricalcitol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)
Status: RECRUITING
Conditions: Arthritis Shoulder
Interventions: PROCEDURE: Glenohumeral Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MPM Prepared From Allogenic Bone Graft in Alveolar Cleft Closure: A Prospective Randomized Clinical Trial
Status: UNKNOWN
Conditions: Cleft; Alveolar Process
Interventions: COMBINATION_PRODUCT: MPM Prepared From Allogenic Bone Graft|OTHER: Autogenous bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation vs. Medical Management for Low Back Pain (DISTINCT)
Status: COMPLETED
Conditions: Chronic Low-Back Pain|Refractory Pain|Neuropathic Pain
Interventions: DEVICE: Spinal Cord Stimulation|OTHER: Conventional Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Bedside Ultrasound Techniques and Standard Methods for Confirmation of Endotracheal Tube Insertion in Intensive Care Patients
Status: RECRUITING
Conditions: Two Bedside|Ultrasound|Endotracheal Tube|Intensive Care Patients
Interventions: DEVICE: Ultrasound using suprasternal method|DEVICE: Ultrasound using subxiphoid method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Litramine in Weight Maintenance
Status: COMPLETED
Conditions: Weight Maintenance|Overweight|Obese
Interventions: DIETARY_SUPPLEMENT: Litramine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback-Assisted Mindfulness Techniques to Reduce Symptoms of Mental Distress
Status: RECRUITING
Conditions: Stress
Interventions: BEHAVIORAL: Neurofeedback training|BEHAVIORAL: Sham Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Vein Stenosis or Occlusion With the Oblique Stent
Status: COMPLETED
Conditions: Iliac Vein Stenosis|Iliac Vein Occlusion
Interventions: DEVICE: Grency venous stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vascular Healing With the Combo Stent Versus the Everolimus Eluting Stent in ACS Patients by Means of OCT
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis|Acute Coronary Syndrome (ACS)|Myocardial Infarction (MI)
Interventions: DEVICE: PTCA with stent placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: tirzepatide|DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")
Status: COMPLETED
Conditions: Prevention of Thromboembolic Events
Interventions: DRUG: BAY2433334 single dose in treatment groups 1-4 and 6 as well as on the dialysis free day of treatment 5|OTHER: BAY2433334 on dialysis treatment day
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Mucositis in Patients With Head and Neck Cancer Treated With Radiotherapy
Status: COMPLETED
Conditions: Radiation- Induced Mucositis|Adverse Effect of Radiation Therapy|Head and Neck Cancer
Interventions: OTHER: Normal saline with salt/Soda|OTHER: Clinacanthus nutans|OTHER: Boesenbergia rotunda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: PEGPH20|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Dexamethasone|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Public Support for COVID-19 Test Allocation
Status: COMPLETED
Conditions: Health Equity|COVID-19
Interventions: BEHAVIORAL: First Come, First Served|BEHAVIORAL: Random|BEHAVIORAL: Disadvantaged Priority & Random
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Core Stabilization Versus Routine Routine Exercises in Pelvic Girdle Pain.
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: OTHER: Core Stabilization exercises|OTHER: Routinely prescribed exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Clinical Efficacy and Safety of Finerenone for the Treatment of IGA Nephropathy
Status: COMPLETED
Conditions: Finerenone|IgA Nephropathy|Proteinuria|Safety Issues
Interventions: DRUG: Finerenone|DRUG: RAS inhibitor|DRUG: Immune Suppressant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selenium in Preventing Cancer Recurrence in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: selenium|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Perioperative Hypothermia in Patients Submitted to Transurethral Resection
Status: COMPLETED
Conditions: Hypothermia; Anesthesia|Perioperative/Postoperative Complications|Complication of Anesthesia|Temperature Change, Body|Anaesthesia Complication|Transurethral Resection Syndrome
Interventions: DEVICE: WarmTouch Model 5900, Covidien Ltd, Mansfield, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of GRT6005 in Patients With Chronic Low Back Pain.
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Matching Placebo|DRUG: Low Dose GRT6005|DRUG: Medium Dose GRT6005|DRUG: High Dose GRT6005|DRUG: Tapentadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Myocilin Genetic Variants on Intraocular Pressure and Pressure Variation in Sitting and Supine Positions
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Cosopt (combination eyedrop of dorzolamide and timolol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of tDCS on Cognitive Control and Emotion Regulation in Depressed Patients
Status: UNKNOWN
Conditions: Anodal Stimulation tDCS|Major Depression|Cognitive Control|Emotion Regulation
Interventions: DEVICE: anodal transcranial direct current stimulation|DEVICE: transcranial direct current stimulation (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: OTHER: Automated peritoneal dialysis|OTHER: Intermittent hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cool Pre-operative TAP Blocks
Status: WITHDRAWN
Conditions: Anesthetics, Local
Interventions: DRUG: Cool Ropivacaine Block|DRUG: Room Temp Ropivacaine Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-human Clinical Trial Evaluating CUR-N399 in Healthy Volunteers.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Enterovirus Infections|Rhinovirus
Interventions: DRUG: CUR-N399|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Bone Metastases
Interventions: DRUG: bisphosphates
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Primary Urethral Realignment vs. Suprapubic Cystostomy for Initial Management of Pediatric Pelvic Fracture Urethral Injury
Status: UNKNOWN
Conditions: Urethral Injury
Interventions: PROCEDURE: Primary realignment|PROCEDURE: Suprapubic cystostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Topical Administration of FOV2304 (High Dose or Low Dose) for the Treatment of Center-involving Clinically Significant Macular Edema Associated With Diabetic Retinopathy
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: 2304 Eye Drops High Dose|DRUG: 2304 Eye Drops Low Dose|DRUG: Placebo Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OUTpatient Intravenous LASix Trial in Reducing Hospitalization for Acute Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Furosemide|DRUG: IV Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Perceived Effectiveness Evaluation of Moisturizing Action of Intimate Use Product in Postmenopausal Women
Status: COMPLETED
Conditions: Female Dry Genital Mucosa
Interventions: DEVICE: KL029 Intimate Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure|Cardiomyopathy
Interventions: DRUG: B-type Natriuretic Peptide (BNP)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation and Dose-Expansion Study of IO-202 and IO-202+Pembrolizumab in Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: IO-202|BIOLOGICAL: IO-202 + pembrolizumab combination therapy|BIOLOGICAL: RP2D of IO-202 + pembrolizumab combination therapy in multiple solid tumor types
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Prenatal Short Messages (SMS) on Maternal and Newborn Health
Status: COMPLETED
Conditions: Short Message Service|Text Messaging
Interventions: BEHAVIORAL: Good household prenatal practice|BEHAVIORAL: Care seeking|BEHAVIORAL: Full bank of SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: iTAPVR Study - Phase II Randomized Study
Status: NOT_YET_RECRUITING
Conditions: Advanced Tumors
Interventions: OTHER: Placebo + conventional treatment including radiotherapy|COMBINATION_PRODUCT: Radiation: Radiation Therapy；Biological: Personalized tumor peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Management Systems in Patients With Type 1 Diabetes (Pediatric SmartHome)
Status: COMPLETED
Conditions: Patient Care|Drug Therapy
Interventions: DEVICE: Medtronic MiniMed 670G Insulin Pump in Auto Mode|DEVICE: Medtronic MiniMed 670G Insulin Pump without Auto Mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of GH on Body Proportions and Final Height in X-Linked Hypophosphatemic Rickets
Status: UNKNOWN
Conditions: Hypophosphatemic Rickets|Growth Disorders|Somatropin Therapy
Interventions: DRUG: somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Onychomycosis: Diagnosis and Prevalence in Diabetic Neuropathic Patients
Status: COMPLETED
Conditions: Prevalence of Onychomycosis|Diabetic Neuropathic Patients|Diagnostic of Onychomycosis|Patients Clinically Suspected of Onychomycosis|Reliability of the Diagnosis of Onychomycosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Total Knee Replacement With Duracon® and Vanguard™ Prostheses
Status: TERMINATED
Conditions: Degenerative Arthritis|Osteoarthritis|Rheumatoid Arthritis|Knee Arthritis
Interventions: DEVICE: Duracon®|DEVICE: Vanguard™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CogStim, a Pilot Study : Cognitive Rehabilitation Management of HIV-1 Mild Cognitively Impaired Patients Controlled With Antiretroviral Therapy
Status: UNKNOWN
Conditions: HIV
Interventions: OTHER: neuropsychological tests|OTHER: STAI-Y scale for anxiety|OTHER: Beck scale for depression|OTHER: without intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Intravenous Infusion of Lidocaine on Patients Undergoing Radical Resection of Colorectal Tumors
Status: COMPLETED
Conditions: Colorectal Tumors|Lidocaine
Interventions: DRUG: Administer 1.5 mg/kg intravenously to the patient before induction of anesthesia, and continue to infuse 1.5 mg/kg/h during the operation until the end of the operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Performance Study of the Edwards SAPIEN 3 Transcatheter Heart Valve/ The SAPIEN 3 Study
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: DEVICE: Edwards SAPIEN 3 Transcatheter Heart Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of Pavlovian and Instrumental Learning in Human Addiction
Status: COMPLETED
Conditions: Healthy|Alcohol Use Disorder (Mild vs. Moderate to Heavy)
Interventions: BEHAVIORAL: Modified training version of the Approach / Avoidance Task (AAT, see Wiers et al., 2011)|BEHAVIORAL: Mindfulness-based interventions (e.g. body scan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zevalin Post-marketing Surveillance for Adequateness of Image Interpretation Criteria in Japan
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma (NHL)
Interventions: DRUG: [111]In-ibritumomab tiuxetan (Zevalin, BAY86-5128)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multi-Centre European Photopatch Test Study
Status: COMPLETED
Conditions: Dermatitis, Photocontact
Interventions: DRUG: 19 organic sunscreen filters and 5 topical NSAIDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003)
Status: RECRUITING
Conditions: Lung Neoplasms|Non-Small-Cell Lung Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab/Vibostolimab|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate the Effect of Food on the Pharmacokinetics of JLP-1310 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes|Hyperlipidemia
Interventions: DRUG: JLP-1310, Fasted followed by fed|DRUG: JLP-1310, Fed followed by fasted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antithymocyte Globulin and Cyclosporine in Preventing Graft-Versus-Host Disease in Patients Undergoing Chemotherapy With or Without Radiation Therapy Followed By Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Graft Versus Host Disease|Leukemia
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cyclosporine|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II GM-CSF Plus Mitoxantrone in Hormone Refractory Prostate Cancer
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Mitoxantrone|DRUG: GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efects of FIFA 11+Warm-Up Program on Agilitiy, Balance And Proprioception Parameters in The Professional Football Players
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: FIFA 11+ warm-up exercise training|OTHER: warm-up exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hypo-pressive Abdominal Exercise on Inspiratory Muscle Strength, Diaphragm Thickness and Pain in Chronic Nonspecific Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Hypo-pressive abdominal exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Studyf of SHR-1701 or Placebo in Combination With BP102 and XELOX in the First-line Treatment of mCRC
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer (mCRC)
Interventions: DRUG: SHR-1701、 BP102 、XELOX|DRUG: SHR-1701、 BP102 、XELOX|DRUG: placebo、 BP102、 XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Postpartum Nurse Navigation Program
Status: COMPLETED
Conditions: Nursing Caries|Nurse's Role|Postpartum Depression|Postpartum Anxiety|Quality of Life|Postpartum Disorder
Interventions: BEHAVIORAL: Postpartum Nurse Navigation Program based care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bortezomib (Velcade) With Standard Chemotherapy for Relapsed or Refractory Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Follicular
Interventions: DRUG: Bortezomib|DRUG: Rituximab|DRUG: Fludarabine|DRUG: Mitoxantrone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engineering Tumor Infiltrating Lymphocytes Injection (GC203 TIL) for the Treatment of Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Gynecologic Cancer|Breast Cancer|Gastrointestinal Cancer|Lung Cancer
Interventions: BIOLOGICAL: Engineering Tumor Infiltrating Lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Open Label Study to Compare the Safety and Efficacy of Subcutaneous Dalteparin Versus Direct Oral Anticoagulants for Cancer-associated Venous Thromboembolism
Status: UNKNOWN
Conditions: Cancer-associated Thrombosis|Esophageal Cancer|Stomach Cancer|Hepatocellular Carcinoma|Pancreatic Cancer|Duodenal Cancer|Esophagogastric Junction Cancer|Malignant Gastrointestinal Stromal Tumor|Ampulla of Vater Cancer|Biliary Cancer (Cholangiocarcinoma, Gall Bladder Cancer)
Interventions: DRUG: Rivaroxaban|DRUG: Dalteparin|DRUG: apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Persistant Organics Pollutants in Breast Cancer.
Status: COMPLETED
Conditions: Breast Cancer|Persistant Organic Pollutants|Lymph Node Metastases
Interventions: OTHER: Blood test sample|OTHER: Peritumoral adipose tissue sample
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer
Interventions: DEVICE: Urinary Bladder Matrix (UBM) sheet device for Venous Leg Ulcers|DEVICE: Urinary Bladder Matrix (UBM) sheet device for Diabetic Foot Ulcers|DEVICE: AmnioExcel Plus for Venous Leg Ulcers|DEVICE: AmnioExcel Plus for Diabetic Foot Ulcers|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Recurrent Multifocal Osteomyelitis - a Bacterial Cause?
Status: UNKNOWN
Conditions: Chronic Recurrent Multifocal Osteomyelitis
Interventions: DIAGNOSTIC_TEST: 18F-NaF-PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: AMG 208 Tumor Microenvironment in Metastatic Castration Resistant Prostate Cancer (mCRPC)
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: AMG 208|BEHAVIORAL: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Analgesia Methods in Patients Undergoing IPACK Block in Knee Arthroplasty
Status: UNKNOWN
Conditions: IPACK Block Multimodal Analgesia|Postoperative NRS Scores
Interventions: DRUG: Dexketoprofen Trometamol|OTHER: spinal anesthesia|OTHER: IPACK|OTHER: PAI|OTHER: Adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia
Status: RECRUITING
Conditions: Chronic Myelogenous Leukemia - Chronic Phase
Interventions: DRUG: asciminib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MICHAEL Method- Fulfilling Individual Potential to Attain Excellence - as a Tool for Improving Metabolic Control and Quality of Life Among Adolescence With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: Michael Method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082)
Status: WITHDRAWN
Conditions: Dyslipidemia
Interventions: DRUG: niacin (+) laropiprant|DRUG: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing High Versus Standard Dose Oseltamivir in Severe Influenza Infection in ICU
Status: TERMINATED
Conditions: Influenza A Virus
Interventions: DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Radiation Therapy for Spinal Tumors
Status: WITHDRAWN
Conditions: Nerve Sheath Tumors|Neurofibroma
Interventions: RADIATION: Proton Radiation for MPNST|RADIATION: Proton Radiation for neurofibromas
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pain Associated With Insertion Torque and Correlation of Primary Implant Stability Measurement Methods
Status: COMPLETED
Conditions: Dental Implantation
Interventions: PROCEDURE: Dental Implantation with high torque|PROCEDURE: Dental Implantation with low torque
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Apatinib in Treating Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Intramuscular CCS/C-adjuvanted Influenza Vaccine in Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: CCS/C|BIOLOGICAL: Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION