pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Letrozole in Treating Postmenopausal Women With Ductal Carcinoma in Situ
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: letrozole|PROCEDURE: MRI|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luteal Supplementation With Rec-LH After GnRH-agonist Triggering in In Vitro (IVF)
Status: UNKNOWN
Conditions: Pregnancy|Pregnancy Loss
Interventions: DRUG: 300IU rec-LH|DRUG: progesterone 600mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEMORI Corps: Activity-based Companion Care for Dementia
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: BEHAVIORAL: MEMORI Corps program|OTHER: Augmented Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Control Trials of Surgery for Pediatric OSA
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Otorhinolaryngologic Diseases|Pediatric Disorder
Interventions: PROCEDURE: ATE|PROCEDURE: APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Crohn's Disease (CD)
Interventions: DRUG: Risankizumab|DRUG: Risankizumab|DRUG: Ustekinumab|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambu Aura-i Laryngeal Mask Versus Air-Q Intubating Laryngeal Airway for Tracheal Intubation in Adults
Status: UNKNOWN
Conditions: Failed or Difficult Intubation (Anaesthesia Complications)
Interventions: DEVICE: Air-Q intubation laryngeal airway|DEVICE: Ambu-Aura i laryngeal mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Open-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD
Status: TERMINATED
Conditions: Late Infantile Metachromatic Leukodystrophy
Interventions: DRUG: HGT-1111
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Dilute Versus Concentrated Heparin for CRRT Anticoagulation
Status: TERMINATED
Conditions: Acute Kidney Injury|Acute Renal Failure|Heart Failure
Interventions: DRUG: Dilute unfractionated heparin|DRUG: Standard concentration unfractionated heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiplatelet vs R-tPA for Acute Mild Ischemic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Aspirin|DRUG: Clopidogrel 75mg|DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Graves' Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in an Open-Label Clinical Extension Study
Status: COMPLETED
Conditions: Thyroid Eye Disease
Interventions: BIOLOGICAL: Teprotumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infrared Pupillometry During General Anesthesia to Predict Pain
Status: TERMINATED
Conditions: Postoperative Pain|Objective Assessment of Sedation
Interventions: DRUG: Anesthesia Premedication, Induction and Maintenance|PROCEDURE: Pupillometry after administration of anesthetic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Colchicine/Statins for the Prevention of COVID-19 Complications (COLSTAT) Trial
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: DRUG: Standard of Care (SOC) and Colchicine+Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elongation Longitudinaux Avec Decoaption Osteo-Articulaire (ELDOA) in Lumbar Disc Protrusion
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: OTHER: Conservative physical therapy management|OTHER: ELDOA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients
Status: TERMINATED
Conditions: Atherosclerosis|Kidney Failure
Interventions: DRUG: tacrolimus|DRUG: mycophenolate mofetil|DRUG: prednisone|DRUG: sirolimus|DRUG: tacrolimus|DRUG: mycophenolate mofetil|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: semaglutide|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Juvista (Avotermin) in the Prevention or Improvement of Scar Appearance Following Scar Revision Surgery.
Status: UNKNOWN
Conditions: Cicatrix
Interventions: DRUG: Avotermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE
Status: COMPLETED
Conditions: Hereditary Angioedema|HAE
Interventions: DRUG: BCX7353 capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Cognitive, Dual-task and Physical Effects of 6 Programs With Older Adults
Status: RECRUITING
Conditions: Physical Fitness|Cognitive Function
Interventions: OTHER: Immersive and Interactive Wall Exergames|OTHER: Complex Cognitive and Motor Activities program|OTHER: exergames program|OTHER: video games program|OTHER: Bike|OTHER: Video games + bike
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Attention Bias Modification Training for Child Anxiety CBT Nonresponders
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: BEHAVIORAL: Attention Bias Modification|BEHAVIORAL: Placebo Attention Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Trisenox Plus Thalomid as Treatment in Patients With Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timmy3 Module Clinical Accuracy ISO 80601-2-56:2017 + A1 2018
Status: ENROLLING_BY_INVITATION
Conditions: Febrile Illness
Interventions: DEVICE: Connex CSVM with Timmy3 module
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CA-LINC Black Youth Suicide Detection and Intervention Study
Status: NOT_YET_RECRUITING
Conditions: Suicide|Suicide Prevention
Interventions: BEHAVIORAL: CA-LINC Intervention|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Complex Posttraumatic Stress Disorder|Stress|Burn Out|Mental Health Issue
Interventions: BEHAVIORAL: Start with the Heart Students|BEHAVIORAL: Start with the Heart Teachers|BEHAVIORAL: Cue Centered Therapy Counselors|BEHAVIORAL: Cue Centered Therapy Students|GENETIC: iSWAB-DNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Nitrous Oxide and Carbon Dioxide for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Pneumoperitoneum
Interventions: PROCEDURE: nitrous oxide use for pneumoperitoneum creation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis
Status: UNKNOWN
Conditions: Bacterial Vaginosis
Interventions: DRUG: N-Acetyl cysteine|DRUG: Metronidazole + N-Acetyl cysteine|DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Cardiovascular Diseases|Metabolic Syndrome X|Atherosclerosis
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Early Treatment of Cytokine Storm Syndrome in Covid-19
Status: COMPLETED
Conditions: Cytokine Storm|COVID-19
Interventions: DRUG: Anakinra|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients
Status: RECRUITING
Conditions: Peritoneum Cancer|Peritoneal Carcinomatosis|Peritoneal Metastases|Colo-rectal Cancer
Interventions: DRUG: PIPAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rituximab Maintenance Therapy in Aggressive CD20 (Cluster of Differentiation Antigen 20) Positive Lymphoma and Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: CD20+ Aggressive Lymphoma, Mantle Cell Lymphoma
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide Versus Bortezomib in Melphalan Refractory Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bortezomib|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Efficacy of Caloric Vestibular Stimulation in the Treatment of Substance Use Disorders
Status: WITHDRAWN
Conditions: Substance Use Disorders
Interventions: DEVICE: ThermoNeuroModulation TNM Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Betaine in Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Cystadane|DRUG: Identical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind, Parallel Group, Comparative Study of Coadministration AD-4833 and SYR-322
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: AD-4833 15 mg|DRUG: AD-4833 30 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: E-learning to Improve Oral Anticoagulant Use in Hospitalized Older People With AF
Status: COMPLETED
Conditions: Simulation Training|Anticoagulant Drugs|Elderly|Atrial Fibrillation|Drug Prescriptions|Internal Medicine|Geriatrics
Interventions: OTHER: E-learning educational program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: "Hypotension Probability Indicator" in TAVI/MitraClip for Hypotension Management
Status: RECRUITING
Conditions: Hypotension During Surgery|Prevention of Hypotension
Interventions: DEVICE: Acumen IQ sensor with Hemosphere monitor incorporating the HPI algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin
Status: TERMINATED
Conditions: Myelodysplastic Syndromes|Leukemia, Myeloid, Acute
Interventions: DRUG: Fludarabine|DRUG: Busulphan|DRUG: Thymoglobuline (Anti-thymocyte globulin [rabbit]) - Genzyme|PROCEDURE: Haematopoietic stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Post-Marketing Safety and Immunogenicity Research of Speeda® Rabies Vaccine for Human Use
Status: COMPLETED
Conditions: Rabies Vaccine Allergy|Vaccination Adverse Event|Anti-D Antibodies
Interventions: BIOLOGICAL: Zagreb2-1-1|BIOLOGICAL: Essen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vortex - Temporary Percutaneous, Transvalvular Circulatory Support System Feasibility Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Temporary Percutaneous Transvalvular Circulatory Support System (Vortex System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness of the Treatment With Continuous Positive Airway Pressure(CPAP)in Stable Heart Failure With Ejection Fraction More Than 45% and Sleep Disordered Breathing
Status: COMPLETED
Conditions: Heart Failure|Sleep Respiratory Disorders
Interventions: PROCEDURE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-directed Video Versus Instructor-based Neonatal Resuscitation Training
Status: COMPLETED
Conditions: Resuscitation of Newborn Training
Interventions: OTHER: Self instructed video learning|OTHER: instructor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mesothelioma
Interventions: PROCEDURE: Pleurectomy/Decortication|DRUG: pemetrexed and cisplatin or carboplatin|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Islet Transplantation for Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: PROCEDURE: Islet Transplantation|DRUG: Sirolimus|DRUG: Tacrolimus|DRUG: Daclizumab|DRUG: Sulfamethoxazole|DRUG: Ganciclovir|DRUG: Trimethoprim|DRUG: Pentamidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Life Therapy for Adults With Hepatitis C Virus and Cirrhosis Awaiting Liver Transplantation
Status: COMPLETED
Conditions: Chronic HCV
Interventions: BEHAVIORAL: Quality of Life Therapy|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Study of Efficacy of Lactobacillus CD2 Lozenges in Preventing High-dose Chemotherapy Induced Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: lactobacillus CD2 lozenges
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Carcinoma|Metastatic Prostate Carcinoma|Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Apalutamide|PROCEDURE: Computed Tomography|DRUG: Degarelix|RADIATION: External Beam Radiation Therapy|OTHER: Fluciclovine F18|DRUG: Goserelin Acetate|PROCEDURE: Intensity-Modulated Proton Therapy|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Leuprolide Acetate|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Relugolix|RADIATION: Stereotactic Body Radiation Therapy|DRUG: Triptorelin|RADIATION: Volume Modulated Arc Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single and Multiple Oral Dose Pharmacokinetic Study of Vigabatrin in Infants With Infantile Spasms
Status: WITHDRAWN
Conditions: Infantile Spasms
Interventions: DRUG: Vigabatrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Probiotics Regulates Skin Care in Children
Status: RECRUITING
Conditions: Skin Care|Probiotics|Children
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotics Lactobacillus salivarius AP-32|DIETARY_SUPPLEMENT: Probiotics Bifidobacterium animalis subsp. lactis CP-9|DIETARY_SUPPLEMENT: Probiotics Lactobacillus rhamnosus LGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Cediranib and Olaparib at the Time Ovarian Cancer Worsens on Olaparib
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Cediranib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized Imaging in Diagnosing Participants With Glioma
Status: RECRUITING
Conditions: Glioma
Interventions: RADIATION: Hyperpolarized Carbon C 13 Pyruvate|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BI 456906 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 456906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
Status: COMPLETED
Conditions: Malaria|Pneumonia
Interventions: DRUG: Artemether-lumefantrine combination|DRUG: amoxycillin|DRUG: paracetamol|DEVICE: malaria rapid diagnostic test, respiratory rate timer|DRUG: Artemether-lumefantrine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Metaphase II Oocytes According to Different Levels of Serum AMH in Poor Responders Using the Antagonist Protocol
Status: UNKNOWN
Conditions: Invitro Fertilizaion
Interventions: DRUG: GnRH antagonist|DRUG: Gonadotropins|DRUG: Human chorionic gonadotropin|PROCEDURE: Embryo transfer|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dehydrated Human Amnion/Chorion Membrane Micrografts(dHACM) Injectable in the Treatment of Recalcitrant Plantar Fasciitis
Status: TERMINATED
Conditions: Plantar Fasciitis
Interventions: PROCEDURE: Injection of 1.0 cc of 0.9% Saline|PROCEDURE: Injection of 1.0 cc of 10 mg/ml micrograft dHACM suspension|PROCEDURE: Injection of 1.0 cc of 20 mg/ml micrograft dHACM suspension|PROCEDURE: Injection of 1.0 cc of 40 mg/ml micrograft dHACM suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Ketorolac tromethamine|DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Nimotuzumab Cisplatin-Vinorelbine in First Line Chemotherapy in Recurring-Persistent Cervical Carcinoma
Status: COMPLETED
Conditions: Cervical Cancer Recurrent or Persistent|Palliative Treatment|Monoclonal Antibody in Cervical Cancer Treatment
Interventions: DRUG: mAb Nimotuzumab|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Continuous Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Resection Versus Transarterial Chemoembolization for the Treatment of Intermediate-stage Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: liver resection|PROCEDURE: transarterial chemoembolization|DRUG: carboplatin|DRUG: lipiodol|DRUG: epirubicin , pirarubicin , hydroxycamptothecin and fluorouracil|OTHER: absorbable gelatin sponge particles
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Sympathetic Denervation in Patients With Hypertension and Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Hypertension|Atrial Fibrillation
Interventions: PROCEDURE: renal sympathetic denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Turmeric Efficacy for Mobility and Joint Function
Status: COMPLETED
Conditions: Knee Discomfort|Joint Pain
Interventions: DIETARY_SUPPLEMENT: Turmipure GOLD®|DIETARY_SUPPLEMENT: Turmeric rhizome PE 95% curcuminoids|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Stabilization Exercises Versus Thrust Manipulation Technique on Pelvic Girdle Pain.
Status: COMPLETED
Conditions: Pelvic Girdle Pain
Interventions: OTHER: Routine physical therapy treatment with the Stabilization exercises|OTHER: Routine physical therapy treatment + High-velocity thrust manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome Transplantation
Status: RECRUITING
Conditions: Bacterial Vaginosis|Microbial Colonization
Interventions: OTHER: chlorhexidine gluconate 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autofluorescence vs Clinical Assessment of Parathyroid Glands During Thyroid Surgery
Status: COMPLETED
Conditions: Hypoparathyroidism Postprocedural
Interventions: DEVICE: Fluobeam® LX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DEVICE: Sapphire II|DRUG: Aftobetin-HCl|RADIATION: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Therapeutic Lactose to Support Vaginal Microbiota
Status: COMPLETED
Conditions: Bacterial Vaginoses
Interventions: DIETARY_SUPPLEMENT: Lactose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aroma on Anxiety Among Children With Autism.
Status: WITHDRAWN
Conditions: Anxiety|Autism Spectrum Disorder
Interventions: OTHER: Test Essential Oil Blend|OTHER: Active Essential Oil Blend|OTHER: Control Blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Caudal Block for Benign Anal Surgery
Status: COMPLETED
Conditions: Anal Fissure|Anal Fistula|Hemorrhoids|Pain, Postoperative
Interventions: PROCEDURE: Ultrasound Guided Caudal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of TC Cream In Treating Patients With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: TC cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 11C-Metomidate PET Versus Adrenal Vein Sampling in Primary Aldosteronism
Status: COMPLETED
Conditions: Primary Hyperaldosteronism
Interventions: PROCEDURE: 11C-Metomidate Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing the Safety and Tolerability of Two Doses of Fipamezole in Adult Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Fipamezole ODT|DRUG: Fipamezole ODT Cohort 2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Increasing the Efficiency of Depression-screening Using Patient-targeted Feedback
Status: COMPLETED
Conditions: Depressive Episode|Chronic Ischaemic Heart Disease|Hypertension
Interventions: OTHER: patient-targeted feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures
Status: COMPLETED
Conditions: Partial Epilepsy
Interventions: DRUG: YKP3089|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy
Status: TERMINATED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: insulin glargine|DRUG: metformin|DRUG: taspoglutide|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preterm Neonates Brain Ultrasound With CEUS and Elastography
Status: NOT_YET_RECRUITING
Conditions: Prematurity
Interventions: DIAGNOSTIC_TEST: Brain contrast enhanced ultrasound, brain ultrasound elastography|DRUG: Sulfur Hexafluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prodromal ImPACT Intervention for Children at Elevated Likelihood of ASD
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Project ImPACT: Improving Parents As Communication Teachers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regional Scalp Block Versus IV Parecoxib for Post-operative Cranioplasty Surgery Pain: A Comparison of Pain Score.
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Ropivacaine 0.75% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Ranolazine to Treat Patients With Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Ranolazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer
Status: COMPLETED
Conditions: Solid Tumors Harboring NTRK Fusion
Interventions: DRUG: Selitrectinib (BAY2731954)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transitioning Together Boston
Status: RECRUITING
Conditions: Autism or Autistic Traits|Family Relations
Interventions: BEHAVIORAL: Transitioning Together (TT) / Juntos en la Transicion (JET)|BEHAVIORAL: Usual autism transition care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine vs Control on Attenuation Hemodynamic Response to Noxious Stimuli in CABG Surgical Patients
Status: NOT_YET_RECRUITING
Conditions: CABG
Interventions: DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness & Safety of Promelaxin® Microenemas Against Macrogol 4000 P.O. in Chronic Constipation in Children 6-48 Months
Status: COMPLETED
Conditions: Chronic Functional Constipation
Interventions: DEVICE: micro-enema with Promelaxin|DRUG: Macrogol 4000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin in Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Postherpetic Neuralgia|Diabetic Polyneuropathies|Other Polyneuropathies
Interventions: DRUG: botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-gp100 Cells Plus ALVAC gp100 Vaccine to Treat Advanced Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma|Skin Cancer
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|BIOLOGICAL: Aldesleukin|BIOLOGICAL: ALVAC gp100 Vaccine|BIOLOGICAL: anti-gp100:154-162 Tcell receptor (TCR) peripheral blood lymphocyte (PBL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polatuzumab, Rituximab and Orelabrutinib Combination Regimen (PRO) in the Treatment of Elderly Frail Patients With Treatment-naive Non-GCB DLBCL
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Polatuzumab vedotin|DRUG: Rituximab|DRUG: Orelabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEARNER- Low dosE AspiRiN prEterm tRial (Angola)
Status: RECRUITING
Conditions: Sickle Cell Disease|Pregnancy Related|Pregnancy Complications|Pre-Eclampsia
Interventions: DRUG: Aspirin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 5-Year Follow-up Study Investigating Factors Associated With Osteoporotic Fracture in Chinese Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporotic Fractures|Osteoporosis, Postmenopausal
Interventions: OTHER: Questionaire survey|RADIATION: Bone mineral density examination|RADIATION: Vertebral fracture assessment|OTHER: Biochemical markers analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain.
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Bupivacaine|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INCMGA00012 in Combination With Chemoradiation in Participants With Stage III Non-Small Cell Lung Cancer (POD1UM-301)
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Retifanlimab|DRUG: Placebo|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Etoposide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Routine Clinical Practice for Use of Intravitreal Aflibercept Treatment in Patients With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mirasol-Treated Platelets - (Pathogen Reduction Extended Storage Study)
Status: TERMINATED
Conditions: Thrombocytopenia
Interventions: BIOLOGICAL: 2-4-day-old Mirasol-treated Platelets Transfusion|BIOLOGICAL: 2-4-day-old Untreated Platelets Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Safety and Efficacy of Xiyanping in Pediatric Participants With Severe Influenza-Like Symptoms
Status: UNKNOWN
Conditions: Severe Influenza
Interventions: DRUG: Oseltamivir Phosphate|DRUG: Xiyanping injection+Oseltamivir Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Incidence of Influenza and Its Complications, in Subjects Aged 50 Years and Over Vaccinated With Fluarix™
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of (PN-152,243)/PN-196,444 in the Prevention of Thrombocytopenia
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: PN-152,243)/PN-196,444
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Personalized Research on Diet in Ulcerative Colitis and Crohn's Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Indeterminate Colitis
Interventions: OTHER: Specific Carbohydrate Diet (SCD)|OTHER: Modified Specific Carbohydrate Diet (MSCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicine in Treating Insomnia
Status: NOT_YET_RECRUITING
Conditions: Insomnia Chronic
Interventions: DRUG: Modified Suan ZaoRen Tang-TianWang BuXin Dan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)
Status: UNKNOWN
Conditions: Scabies
Interventions: DRUG: InfectoScab 5 % Creme|DRUG: Permethrin 10 % Creme|DRUG: Driponin 3 mg Tabletten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Fixed-Sequence, Two-Period, Open-Label Drug-Drug Interaction Study to Assess the Effect of an Inhibitor of Cytochrome P450 Isoenzyme 3A4 and Permeability Glycoprotein 1 on the Pharmacokinetics of TD-1211
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TD-1211|DRUG: TD-1211+ itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Manipulative Medicine (OMM) on Pulmonary Function and Speech in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: Osteopathic Manipulative Medicine Treatment|OTHER: Light Touch sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topotecan, Cisplatin, and Radiation Therapy in Treating Patients With Advanced Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|DRUG: topotecan hydrochloride|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Dose Response of 3 Doses of Euphorbia Prostrata in Patients With First and Second Degree Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Euphorbia tablets|DRUG: Euphorbia tablets|DRUG: Euphorbia tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET)
Status: UNKNOWN
Conditions: Recovery of Function
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside and Pterostilbene|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement
Status: COMPLETED
Conditions: Stroke|Problem of Aging
Interventions: DIETARY_SUPPLEMENT: quercetin/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tarceva (Erlotinib) and Gemcitabine in Treatment-Naive Patients With Advanced Non-Small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sleeve Gastrectomy Risks and Benefits
Status: ENROLLING_BY_INVITATION
Conditions: Renal Failure
Interventions: DIAGNOSTIC_TEST: 6 minutes walk distance|BEHAVIORAL: Activity Monitor|BEHAVIORAL: Continuous Glucose Monitor|BEHAVIORAL: Blood Pressure Monitoring|DIAGNOSTIC_TEST: Blood Pressure Monitoring|DIAGNOSTIC_TEST: Body Composition Scan|DIAGNOSTIC_TEST: Mixed meal testing|DIAGNOSTIC_TEST: Quality of Life
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IDUS in CBD Stone Recurrence High Risk Patients
Status: RECRUITING
Conditions: Choledocholithiasis|Cholangiopancreatography, Endoscopic Retrograde|Ultrasonography
Interventions: PROCEDURE: IDUS examination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Mobile Artificial Cervical Vertebrae Replacement for Patients With Cervical Spondylosis
Status: UNKNOWN
Conditions: Cervical Spondylosis
Interventions: PROCEDURE: mobile artificial cervical vertebrae replacement|PROCEDURE: anterior cervical corpectomy and fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Stress Reactivity in Schizophrenia: Integrated Coping Awareness Therapy
Status: COMPLETED
Conditions: Schizophreniform Disorders
Interventions: BEHAVIORAL: I-CAT|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Teriparatide in Diabetic Inactive Charcot Neuroarthropathy of Foot
Status: COMPLETED
Conditions: Diabetic Neuropathic Arthropathy
Interventions: DRUG: Teriparatide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Soluble Neprilysin, NT-proBNP, and Growth-Differentiation-Factor-15 as Biomarkers for Heart Failure in Dialysis Patients
Status: COMPLETED
Conditions: Heart Failure|End Stage Renal Disease
Interventions: DIAGNOSTIC_TEST: Diagnostic biomarker study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Biomatrix and Orsiro Drug Eluting Stent
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: Orsiro drug eluting stent|DRUG: Biomatrix drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Stem Cell Based Tissue Engineered Laryngeal Implants
Status: WITHDRAWN
Conditions: Disorder of Upper Respiratory System|Laryngostenosis|Tracheal Stenosis
Interventions: OTHER: Stem cell based tissue engineered partial laryngeal implants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Benefits of a Short Spa Treatment on the Elimination of Residual Lithic Fragments After Treatment
Status: TERMINATED
Conditions: Calculi, Urinary
Interventions: DEVICE: Hydroposturotherapy|DEVICE: Standard support in urology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Comparison of the Use of JET and Conventional Ventilation in Pulmonary Vein Isolation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Jet Ventilation|DEVICE: Conventional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Copper Cu 64-DOTA-B-Fab PET/CT in Imaging Patients With Ovarian and Breast Cancer
Status: TERMINATED
Conditions: Ovarian Carcinoma|Breast Carcinoma
Interventions: DIAGNOSTIC_TEST: Computed Tomography|DRUG: Copper Cu 64-DOTA B-Fab|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DIAGNOSTIC_TEST: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia
Status: WITHDRAWN
Conditions: Friedreich Ataxia
Interventions: DRUG: Nicotinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effects of Infraorbital Nerve Block in Cleft Palate Surgery
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: INFRA ORBITAL BLOCK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Albuterol to Improve Respiratory Strength in SCI
Status: TERMINATED
Conditions: Spinal Cord Injury|Respiratory Muscle Weakness
Interventions: DRUG: Oral Albuterol Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT