pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Renin-angiotensin-aldosterone System Polymorphisms in Resistant Hypertension and Adverse Cardiovascular Events
Status: COMPLETED
Conditions: Systemic Arterial Hypertension|Hypertension Resistant to Conventional Therapy|Myocardial Infarction|Stroke
Interventions: DRUG: Anti-hypertensive drug treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Treatment A: Naloxone Nasal Spray|DRUG: Treatment B: Naloxone Nasal Spray|DRUG: Treatment C: Naloxone HCL Intramuscular (IM) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and Granulocyte Colony Stimulating Factor (G-CSF) as Compared to Placebo and G-CSF for the Mobilization of Hematopoietic Stem Cells for Autologous Transplantation in Subjects With Multiple Myeloma (MM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: BL-8040 1.25 mg/kg + G-CSF|DRUG: Placebo +G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Multi-center Study to Evaluate the Efficacy and Safety of ONO-2952 in Female Subjects With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: DRUG: ONO-2952|DRUG: ONO-2952 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 0.01% Hypochlorous Acid in the Treatment of Blepharitis
Status: RECRUITING
Conditions: Blepharitis
Interventions: DRUG: 0.01% hypochlorous acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Probiotic Supplement on Quality of Life
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Non-cystic Fibrosis Bronchiectasis
Interventions: DIETARY_SUPPLEMENT: Probiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology
Status: WITHDRAWN
Conditions: Autistic Disorder
Interventions: DRUG: Bumetanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Formula With Modified Content of Protein and Improved Fatty Acids and Their Impact on Infant Growth and Health
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: OTHER: standard infant formula|OTHER: modified infant formula|OTHER: breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Community-based, Controlled, Open-label, Cluster-randomized Trial for the Reduction of Chronic Malnutrition in Children Under Two Years of Age, With Three Intervention Arms Grouped by Clusters, in Two Provinces in Southern Angola, Huíla and Cunene.
Status: ACTIVE_NOT_RECRUITING
Conditions: Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplementation|BEHAVIORAL: Money transfers|BEHAVIORAL: Standard intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mavrilimumab to Reduce Progression of Acute Respiratory Failure in COVID-19 Pneumonia and Systemic Hyper-inflammation
Status: COMPLETED
Conditions: COVID 19|SARS-CoV 2|Pneumonia
Interventions: DRUG: Mavrilimumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ibuprofen 250 mg / Acetaminophen 500 mg Comparing The Antipyretic Effects in Healthy Male Volunteers
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: Ibuprofen 250 mg / Acetaminophen 500 mg|DRUG: Ibuprofen 250 mg|DRUG: Acetaminophen 500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tc 99m Tilmanocept Imaging for Early Prediction of Anti-TNFα Therapy Response in Moderate to Severe Active RA
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: TC99m-tilmanocept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Olanzapine for the Treatment of Chronic Nausea and/or Vomiting in Patients With Advanced Cancer
Status: WITHDRAWN
Conditions: Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: DRUG: Olanzapine|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fatty Acid Synthase Inhibition in Castration Refractory Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Refractory Cancer|Castration Resistant Prostatic Cancer
Interventions: DRUG: Omeprazole 80 mg twice daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SLEEVEDIAB To Explore the Early and Late Metabolic Effects of Sleeve Gastrectomy in Obese Patients
Status: UNKNOWN
Conditions: Severe Obesity|Type 2 Diabetes
Interventions: OTHER: Caloric restriction|OTHER: No caloric restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Endometrial Injury Improve Intrauterine Insemination Outcome?
Status: COMPLETED
Conditions: Infertility
Interventions: PROCEDURE: endometrial injury.|PROCEDURE: intrauterine insemination|DRUG: ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine-CHOP for Patients With Nodal T-cell Lymphoma With T-follicular Helper Phenotype (ACANTUS)
Status: RECRUITING
Conditions: T Cell Lymphoma
Interventions: DRUG: ACHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of Mirabegron, a New beta3-adrenergic Receptor in the Prevention of Heart Failure
Status: UNKNOWN
Conditions: Hypertrophy, Left Ventricular
Interventions: DRUG: mirabegron|PROCEDURE: Echocardiography|PROCEDURE: Cardiac MRI|PROCEDURE: Maximal exercise capacity|PROCEDURE: Blood sampling|PROCEDURE: Endothelial function measurement|RADIATION: 18FDG-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of PDC-339 for the Treatment of Acute Erosive Gastritis
Status: COMPLETED
Conditions: Erosive Gastritis
Interventions: DRUG: PDC339|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo TCR αβ T Cell Depletion for Graft-Versus-Host Disease Prophylaxis in Mismatched Donor Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies
Status: TERMINATED
Conditions: Hematologic Malignancy
Interventions: DEVICE: ClinicMACs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Repeat Doses of CSL324 in Subjects With Hidradenitis Suppurativa and Palmoplantar Pustulosis
Status: COMPLETED
Conditions: Hidradenitis Suppurativa|Palmoplantar Pustulosis
Interventions: BIOLOGICAL: Recombinant anti-granulocyte colony-stimulating factor (G-CSF) receptor monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide for Hematopoietic Stem Cell Mobilization in Patients With a Hematologic Malignancy
Status: COMPLETED
Conditions: Hematologic Malignancies
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Mechanism of Custom-made Foot Orthoses in Patients With Chronic Low Back Pain
Status: UNKNOWN
Conditions: Chronic Low Back Pain|Foot Pronation
Interventions: DEVICE: Custom-made foot orthoses Versus a flat insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Double Dose Oral Terbinafine Vs Itraconazole in Treatment of Dermatophyte Infections of Skin.
Status: COMPLETED
Conditions: Dermatophyte Infection|Terbinafine Adverse Reaction|Itraconazole Adverse Reaction
Interventions: DRUG: Terbinafine Pill|DRUG: Itraconazole capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Do Flavors Increase the Addiction Potential of Nicotine?
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine|DEVICE: JUUL e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COPD Care Pathway Among Patients With Cancer
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease|Lung Cancer|Head and Neck Cancer
Interventions: OTHER: Surveys and Interviews - Arm A|OTHER: COPD Care Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Compare AMG 510 "Proposed INN Sotorasib" With Docetaxel in Non Small Cell Lung Cancer (NSCLC) (CodeBreak 200).
Status: ACTIVE_NOT_RECRUITING
Conditions: KRAS p, G12c Mutated /Advanced Metastatic NSCLC
Interventions: DRUG: AMG 510|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self Reported Oral Health, Awareness and Attitude Towards Dental Care Among Pregnant Women
Status: UNKNOWN
Conditions: Pregnancy|Oral Health|Attitude|Oxidative Stress
Interventions: OTHER: Information|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Boceprevir Treatment in Liver Pre-transplant HCV Patients
Status: UNKNOWN
Conditions: Late Complication From Liver Transplant
Interventions: DRUG: Boceprevir 800mg/TID+Pegylated interferon alfa+Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Simulated Obstructive Apnoea and Hypopnoea on Heart Rhythm in Patients With Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Patients With Paroxysmal Atrial Fibrillation
Interventions: OTHER: Mueller manoeuvre|OTHER: Inspiratory threshold|OTHER: Expiratory apnoea|OTHER: Steady state normal breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Immunogenicity of V116 in Adults With Increased Risk for Pneumococcal Disease (V116-008)
Status: COMPLETED
Conditions: Pneumococcal Infection
Interventions: BIOLOGICAL: V116|DRUG: Placebo for PCV15 + PPSV23|BIOLOGICAL: PCV15|BIOLOGICAL: PPSV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Placebo-controlled Study Investigating the Effects of Moxaverine on Ocular Blood Flow After Oral Administration in Healthy Subjects
Status: COMPLETED
Conditions: Effect of Orally Administrated Moxaverine on Ocular Blood Flow
Interventions: DRUG: Moxaverine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neurofeedback and Neural Plasticity of Self-Processing and Affect Regulation Circuits in Suicide Attempting Adolescents
Status: COMPLETED
Conditions: Suicide, Attempted|Suicide, Ideation|Depression
Interventions: OTHER: neurofeedback training involving dACC|OTHER: neurofeedback training involving amygdala
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Furosemide Withdraw in Stable Chronic Heart Failure Outpatients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Placebo|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Poverty And Related Social Determinants to Improve Knowledge of and Links to Resources (SPARK)
Status: NOT_YET_RECRUITING
Conditions: Poverty
Interventions: BEHAVIORAL: Community Health Worker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diagnostic Yield of Transvaginal Ultrasonography Versus Sonohysterography in Detection of Ceserean Section Niche
Status: UNKNOWN
Conditions: Cesarean Section Niche Evaluation
Interventions: DIAGNOSTIC_TEST: sonohysterography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HFNC During Bronchoscopy for Bronchoalveolar Lavage
Status: COMPLETED
Conditions: Acute Respiratory Failure|Bronchoscopy|Bronchoalveolar Lavage
Interventions: DEVICE: High Flow Nasal Cannula|DEVICE: Conventional Oxygen Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Pharmacokinetic Study of Fluticasone Furoate /Umeclidinium Bromide/Vilanterol (100/62.5/25 Microgram [mcg]) After Single and Repeat Dose Administration From a Dry Powder Inhaler in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF|DRUG: VI/UMEC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorders
Status: NOT_YET_RECRUITING
Conditions: Mood Disorders|Suicidal Ideation|Depressive Episode
Interventions: DRUG: Subanesthetic dose intravenous esketamine|DEVICE: Modified electroconvulsive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Food Effects of Herombopag Olamine Tablets in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Adult Patients With Chronic Primary ITP|Adult Patients With SAA Who do Not Respond Well to Immunosuppressive Therapy
Interventions: DRUG: Herombopag Olamine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Viscosupplementation After Partial Meniscectomy: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Meniscus Lesion
Interventions: BIOLOGICAL: hyaluronic acid|PROCEDURE: meniscectomy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Flexor Retinaculum Stretch and Carpal Mobilizations in Patients With Carpal Tunnel Syndrome.
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Carpal bone mobilization|OTHER: Flexor retinaculum stretch|OTHER: Carpal bone mobilization and flexor retinaculum stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Normalcy of Food Intake in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Neoplasms, Head and Neck
Interventions: OTHER: Swallow therapy in combination with individual dietary counselling|OTHER: Individual dietary counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maraviroc (CCR5) Antagonism to Decrease the Incidence of the Immune Reconstitution Inflammatory Syndrome in HIV-Infected Patients
Status: UNKNOWN
Conditions: Immune Reconstitution Inflammatory Syndrome|HIV|HIV Infections
Interventions: DRUG: maraviroc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis
Status: COMPLETED
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: DIETARY_SUPPLEMENT: Eicosapentaenoic acid, Gamma-Linolenic Acid and Antioxidant Vitamins|DIETARY_SUPPLEMENT: Standard ICU enteral diet, isocaloric to the study diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Resin Matrix Ceramic Posterior Crowns
Status: RECRUITING
Conditions: Dental Materials
Interventions: PROCEDURE: Resin-matrix|PROCEDURE: Monolithic zirconia|PROCEDURE: Metal-ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoids in COVID-19 (CORTIVID)
Status: COMPLETED
Conditions: Covid-19 Pneumonia
Interventions: DRUG: Methylprednisolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Airway Responses to Montelukast and Desloratadine.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Montelukast (10mg) and Desloratadine (5mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Digital Window on Day and Night Perception Status and Sleep Quality in Intensive Care Patients
Status: UNKNOWN
Conditions: Coronary Artery Diseases|Heart Valve Diseases
Interventions: BEHAVIORAL: Digital Window
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PRCT: Comparing Two Procedures for Ulno-Carpal Abutment Syndrome.
Status: TERMINATED
Conditions: Joint Disease
Interventions: PROCEDURE: Wafer Procedure|PROCEDURE: Ulnar shortening osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ilioinguinal Single-shot and Three-layer Blocks
Status: TERMINATED
Conditions: Ilioinguinal Nerve Block|Local Anesthesia|Post-operative Analgesia
Interventions: PROCEDURE: 3-layer block|PROCEDURE: Single-shot block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Warrior CARE: Cannabis Behavioral Health
Status: NOT_YET_RECRUITING
Conditions: Post Traumatic Stress Disorder|Cannabis Use|Suicide|Veterans|Marijuana
Interventions: DRUG: Tetrahydrocannabinol|DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Check@Home: General Population Screening for Early Detection of Atrial Fibrillation and Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Chronic Kidney Diseases|Diabetes Mellitus, Type 2
Interventions: OTHER: Intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hepatitis C Virus(HCV) Heart and Lung Study
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Heart Failure|Pulmonary Disease, Chronic Obstructive|Lung Diseases, Interstitial
Interventions: DRUG: Sofosbuvir/ledipasvir fixed dose combination(SOF/LDV FDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASDactive: An Integrated Theory-based Intervention to Promote Habitual Physical Activity
Status: RECRUITING
Conditions: Physical Inactivity|Sedentary Behavior|Autism|Autism Spectrum Disorder|Asperger Syndrome|Behavioral
Interventions: BEHAVIORAL: ASDactive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost SR|DRUG: LUMIGAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Vasoconstriction
Interventions: DRUG: BQ-788|DRUG: BQ-123|DRUG: L-Arginine|DRUG: NG Nitro L Arginine Methyl Ester|DRUG: Sodium Nitroprusside|DRUG: Lactated Ringer's
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health
Status: NOT_YET_RECRUITING
Conditions: Healthy Diet|Cholesterol|Healthy Lifestyle|Healthy Nutrition
Interventions: DIETARY_SUPPLEMENT: Olives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination or Sequential Therapy of Peginterferon Alfa-2a and Entecavir for Patients With Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peg-IFNα-2a|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Sedation With Propofol Versus Anesthesiologist-administered Sedation for Orthopedic Surgery
Status: NOT_YET_RECRUITING
Conditions: Orthopedic Disorder
Interventions: PROCEDURE: orthopaedic surgery|DRUG: propofol anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Ways to Improve OVC HIV Prevention and Well-being
Status: COMPLETED
Conditions: Risk Behavior|Mental Health Impairment
Interventions: BEHAVIORAL: Trauma-Focused Cognitive Behavioral Therapy|BEHAVIORAL: Psychosocial Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol & Men's Sexual Risk Behaviors
Status: ACTIVE_NOT_RECRUITING
Conditions: Sexual Behavior|Alcohol Drinking|Sexual Aggression|Emotions
Interventions: BEHAVIORAL: Alcoholic Beverage|BEHAVIORAL: Non-alcoholic Beverage|BEHAVIORAL: Partner Negative Mood Manipulation|BEHAVIORAL: Partner Positive Mood Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD
Status: COMPLETED
Conditions: COPD|Chronic Obstructive Pulmonary Disease|Chronic Obstructive Pulmonary Disease Severe|Chronic Obstructive Pulmonary Disease Moderate
Interventions: OTHER: Wellinks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PVAG-14 Pilot for Intermediate Stages Hodgkin Lymphoma
Status: TERMINATED
Conditions: Hodgkin Lymphoma
Interventions: DRUG: prednisone|DRUG: vinblastine|DRUG: doxorubicin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Field Ablation Versus Conventional Radiofrequency Catheter Ablation for Repeat PVI in Patients With Paroxysmal AF
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation Recurrent
Interventions: DEVICE: pulmonary vein isolation with RFA|DEVICE: pulmonary vein isolation with PFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Flow and High Flow Anesthesia on Thiol-Disulfide Homeostasis and IMA in Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: PROCEDURE: low and high flow Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Inflammation and Brain Function - Pilot Study
Status: COMPLETED
Conditions: Sickness Behavior
Interventions: BIOLOGICAL: Lipopolysaccharide|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The SPIN - Scleroderma Support Group Leader EDucation Program Trial (SPIN-SSLED)
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: OTHER: SPIN-SSLED Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Evaluating Megestrol Acetate Modulation in Hormone Receptor Positive Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: DRUG: Megestrol Acetate 160Mg Tablet|DRUG: Anastrozole 1Mg Tablet|DRUG: Letrozole 2.5Mg Tablet|DRUG: Exemestane 25 MG|DRUG: Tamoxifen 20Mg Tablet|DRUG: Fulvestrant 50Mg Solution for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: School Based Malaria Control in Ugandan Schoolchildren
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Four monthly IPT with dihydroartemisinin Piperaquine (DP)|DRUG: Monthly IPT using DP|DRUG: Placebo given every month
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Expertise-Based Randomized Controlled Trial of Scrotal Versus Inguinal Orchidopexy on Post-operative Pain
Status: COMPLETED
Conditions: Low-lying Unilateral Palpable Undescended Testis
Interventions: PROCEDURE: Scrotal Orchidopexy|PROCEDURE: Inguinal Orchidopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Low-dose Glucocorticoid Prophylaxis for Acute Graft-versus-host Disease(GVHD)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: low-dose glucocorticoid Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pertrochanteric Fracture Fixation In Elderly Adults Using Proximal Femoral Nail Anti-rotation (HERACLES) With a T-shaped Parallel Blade: A New Design
Status: UNKNOWN
Conditions: Pertrochanteric Fracture|Intertrochanteric Fractures|Pertrochanteric Fracture of Femur, Closed|Pertrochanteric Fracture of Femur, Open
Interventions: DEVICE: Proximal femoral nail with straight parallel blade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.
Status: COMPLETED
Conditions: Headache
Interventions: DRUG: Metoclopramide|DRUG: Diphenhydramine|DRUG: Codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Evaluate the Safety and Pharmacokinetic Characteristics After the Administration of JC-001 and JLP-1901
Status: COMPLETED
Conditions: Healthy Adult
Interventions: DRUG: JLP-1901|DRUG: JC-001(active comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Management Program for World Trade Center (WTC) Responders
Status: COMPLETED
Conditions: PTSD|Signs and Symptoms, Respiratory
Interventions: BEHAVIORAL: Relaxation Response Resiliency Program (3RP)|BEHAVIORAL: Health Enhancement Program (HEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth With Mental Health Conditions
Status: RECRUITING
Conditions: Mental Health Wellness 1|Mental Health Wellness 2|Occupational Problems
Interventions: BEHAVIORAL: iCareer Soft Skills Training for Employment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Trial in Early Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration (AMD)
Interventions: DIETARY_SUPPLEMENT: Lutein-enriched-egg beverage (NWT-02)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D, K2 Plus Empagliflozin Combination in Type Two Diabetes Mellitus
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Oral Hypoglycemic Agents,Oral|DRUG: Voreta|DRUG: Voreta plus SunnyD PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Antimicrobial Activity of 2 Test Toothpastes
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: Test zinc-IPMP toothpaste|OTHER: Test zinc non- IPMP toothpaste|OTHER: Positive control|OTHER: SLS negative control|OTHER: non-SLS negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy of Tolterodine Prolonged Release Compared With Propiverine for the Treatment of Korean Patients With Overactive Bladder as Assessed by Ambulatory Urodynamic Monitoring
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: propiverine|DRUG: tolterodine PR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Sotagliflozin (SAR439954)|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of Oral Anticoagulation in Left Ventricular Thrombi
Status: COMPLETED
Conditions: Anticoagulants; Increased|Left Ventricular Thrombosis
Interventions: DRUG: Rivaroxaban 20 MG|DRUG: Warfarin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: Decompression prototype splint for carpal tunnel syndrome|DEVICE: Standard splint for carpal tunnel syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing LBAL to Humira® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: LBAL|DRUG: Humira®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In-Vivo Assessment of Adipose Allograft Extracellular Matrix in Abdominoplasty Patients
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Adipose Allograft Extracellular Matrix (AAM) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Relationship of Disability With Depression, Anxiety and Sleep Quality in Patients With Coccygodynia
Status: UNKNOWN
Conditions: Coccyx Injuries|Pain, Chronic|Anxiety|Depression|Sleep|Sleep Hygiene
Interventions: BEHAVIORAL: Owstery Disability Scale for disability Beck Depression Scale, Beck Anxiety Scale for psychological evaluation, VAS for pain, Pittsburgh Sleep Quality Scale for sleep quality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MEDPass Trial: MedPass Versus Conventional Administration of Oral Nutritional Supplements
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: MEDPass mode of administration|DIETARY_SUPPLEMENT: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TDM-105795 in Male Subjects With Androgenetic Alopecia (AGA)
Status: COMPLETED
Conditions: Alopecia, Androgenetic
Interventions: DRUG: TDM-105795|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Conditioning (RIC) Regimen and Post-transplant Cyclophosphamide in Haploidentical Bone Marrow Transplantation in in Patients With Poor Prognosis Lymphomas
Status: UNKNOWN
Conditions: Lymphoma
Interventions: DRUG: Thiotepa|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Muscle Energy Technique Versus Myofascial Mobilization in Managing Sub-acute Low Back Pain
Status: COMPLETED
Conditions: Lordosis|Low Back Pain
Interventions: OTHER: Physiotherapy|OTHER: Muscle Energy technique|OTHER: Myofacial mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Treating First Episode Psychosis With Folic Acid,B12 and B6 in Addition to Antipsychotic Medication
Status: COMPLETED
Conditions: First Episode Psychosis
Interventions: DRUG: Folic Acid 5mg, Vitamin B12 0.4mg and B6 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vaccination on Turnover of Lamivudine (3TC) Sensitive and Resistant Virus Populations in HIV-1-Infected Individuals
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: Influenza Virus Vaccine|BIOLOGICAL: Pneumococcal Vaccine, Polyvalent (23-valent)|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia|L1 Childhood Acute Lymphoblastic Leukemia|L2 Childhood Acute Lymphoblastic Leukemia|Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: DRUG: vincristine sulfate|DRUG: prednisone|DRUG: doxorubicin hydrochloride|DRUG: pegaspargase|DRUG: cytarabine|DRUG: methotrexate|DRUG: dexamethasone|DRUG: etoposide|DRUG: cyclophosphamide|DRUG: leucovorin calcium|BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femoral Versus Psoas Continuous Peripheral Nerve Blocks Following Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthroplasty|Hip Pain
Interventions: PROCEDURE: Femoral Nerve Block vs. Psoas Compartment Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Houston "Breathe Easy" Healthy Homes-Based Model for Multifamily Rental Communities
Status: UNKNOWN
Conditions: Asthma|Respiratory Tract Disease|Lung Diseases|Sinusitis, Chronic
Interventions: BEHAVIORAL: Exposure-Reduction Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Trainer System (3rd Version) for Physical Activity Promotion in Middle-aged Hong Kong Adults
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Follow Your Virtual Trainer (FYVT) program|OTHER: Daily PA recommendation & healthy lifestyle suggestions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Everolimus|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Called FLAMINgO to Learn More About the Treatment Combination of Finerenone and SGLT2 Inhibitors in People With Long-term Kidney Disease (Chronic Kidney Disease) Together With Type 2 Diabetes by Using Routine Medical Care Data and Past Clinical Study Results
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes
Interventions: DRUG: Finerenone (Kerendia, BAY94-8862)|DRUG: Sodium-glucose cotransporter-2 inhibitors (SGLT2i)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Dexmedetomidine on Neuroendocrine Stress Hormone Release and Heart Rate Variability in Patients Undergoing Major Spinal Surgery
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: DRUG: dexmedetomidine group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes
Status: UNKNOWN
Conditions: Pancreatic Neoplasms
Interventions: DRUG: Gemcitabine|RADIATION: TS-1 with radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kanagawa Valsartan Trial (KVT): Effects of Valsartan on Renal and Cardiovascular Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hypertension
Interventions: DRUG: valsartan|DRUG: Conventional antihypertensive drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sectional Versus Full Glass Ceramic Laminate Veneers
Status: ACTIVE_NOT_RECRUITING
Conditions: Spacing of Anterior Teeth
Interventions: PROCEDURE: Glass ceramic sectional veneer|PROCEDURE: Glass ceramic laminate veneer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chinese Herbal HuoXue LiShui Formula for Chronic Subdural Hematoma
Status: NOT_YET_RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: DRUG: Chinese Herbal formula HuoXue LiShui|DRUG: Chinese Herbal formula Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nyaditum Resae(R) Against Active TB in Georgia
Status: UNKNOWN
Conditions: Close Contacts of Active Tuberculosis
Interventions: BIOLOGICAL: Nyaditum resae(R)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strength and Nutrition Outcomes for Latino Adolescents
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes|Cardiovascular Risk|Cancer
Interventions: BEHAVIORAL: Nutrition|BEHAVIORAL: Strength Training & Nutrition|BEHAVIORAL: Circuit Training & Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stress Level Among Dentists in Performing Treatment
Status: COMPLETED
Conditions: Stress, Job
Interventions: DIAGNOSTIC_TEST: Blood pressure (Systolic, Diastolic), Pulse value, O2 saturations were measured.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Nociception Level During Opioid-sparing Anaesthesia Versus Conventional Opioid-based Anaesthesia
Status: RECRUITING
Conditions: Analgesia
Interventions: DRUG: conventional opioid-based group|DRUG: opioid-sparing group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability and Electroencephalography Analysis in Laparoscopic Surgery With or Without Transversus Abdominis Plane Block
Status: RECRUITING
Conditions: Autonomic Nervous System|Nerve Block|Laparoscopy|Anesthesia and Analgesia|EEG
Interventions: PROCEDURE: transversus abdominis plane block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD)
Status: RECRUITING
Conditions: Opioid Use Disorder (OUD)
Interventions: DRUG: SL-BUP|DRUG: XR-BUP|DRUG: XR-NTX|BEHAVIORAL: MM|BEHAVIORAL: MMR|BEHAVIORAL: MMD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine and Chlorphenesin Carbamate in Combination With mFOLFIRINOX in Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Chlorphenesin Carbamate, Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided IMagery and Patient Satisfaction (GIMPS) Following Urogynecological Surgery
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: BEHAVIORAL: Guided IMagery (GIM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of Trivalent Influenza Vaccine in Non-pregnant HIV-infected Women
Status: COMPLETED
Conditions: Influenza|Human Immunodeficiency Virus
Interventions: BIOLOGICAL: Trivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tendon Adaptations to Training - Effect of Ageing
Status: UNKNOWN
Conditions: Aging|Exercise Training|Connective Tissue|Skeletal Muscle
Interventions: OTHER: Strength training at 80% 1RM|OTHER: Strength training at 55% 1RM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Type-A Botulinum Toxin in the Post-radiosurgical Neck Contractures
Status: COMPLETED
Conditions: Cervical Spasm|Radiotherapy Side Effect|Botulinum Toxin
Interventions: DRUG: Botulinum toxin A|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Trial Between Two Repellent Products and a Positive Control Against Culicoides Nubeculosus Midges
Status: COMPLETED
Conditions: Midge Bites
Interventions: OTHER: p-Menthane,3-8-diol (PMD) Topical Repellent|OTHER: Picaridin Topical Repellent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION