pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Phase Ⅱ Study of Chidamide in Combination With CHOP in Previously Untreated Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype
Status: RECRUITING
Conditions: Peripheral T-Cell Lymphoma With Follicular Helper of T Cell Phenotype
Interventions: DRUG: Chidamide combined with CHOP|DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tayside Rehabilitation in Bronchiectasis Exacerbations (TRIBE) : a Randomized Controlled Trial
Status: TERMINATED
Conditions: Bronchiectasis
Interventions: PROCEDURE: Pulmonary rehabilitation|PROCEDURE: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Looking Into the Effect of NNC 55-0414 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: NNC 55-0414
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males
Status: RECRUITING
Conditions: Male Contraception
Interventions: DRUG: YCT-529|DRUG: YCT-529 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Campath-1H and Allogeneic Blood Stem Cell Transplantation for Lymphoid Malignancies
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Chronic|Leukemia, Lymphocytic, Acute|Lymphoma, Low-Grade|Lymphoma, T-Cell|Lymphoma, B-Cell
Interventions: DRUG: Campath-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oregovomab in Combination With Bevacizumab Plus Chemo in BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer by FIGO Stage|Ovarian Cancer Stage III|Ovarian Cancer Stage IV
Interventions: BIOLOGICAL: Oregovomab|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PUSH Notifications From a Mobile App for Improving the Body Composition of Overweight or Obese Women
Status: UNKNOWN
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Control Group (CG)|BEHAVIORAL: Moderate physical activity group (MPA)|BEHAVIORAL: Intense physical activity group (IPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Attitudes Toward Human Papillomavirus and Influenza Vaccination Among Mothers of Early Adolescents
Status: COMPLETED
Conditions: Human Papillomavirus Vaccines|Influenza Vaccines|Attitude to Health
Interventions: BEHAVIORAL: Provider Communication about Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea
Status: UNKNOWN
Conditions: Sleep Apnea Syndromes
Interventions: DRUG: Ketamine + propofol|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Laser Immunotherapy With and Without Topical Anti-PD1 in Basal Cell Carcinomas
Status: UNKNOWN
Conditions: BCC - Basal Cell Carcinoma|Immune Response|Immunotherapy|Ablative Fractionated Laser
Interventions: DRUG: Nivolumab 10 MG/ML|DEVICE: Ablative fractionated laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccine in Treating Patients With Indolent B-Cell Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: autologous lymphoma cell lysate-pulsed autologous dendritic cell vaccine|BIOLOGICAL: autologous lymphoma cell/allogeneic dendritic cell electrofusion hybrid vaccine|BIOLOGICAL: autologous lymphoma cell/autologous dendritic cell electrofusion hybrid vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Indigenously Adapted Cognitive Behavioral Therapy for Reducing Gaming Addiction Among Adolescents
Status: COMPLETED
Conditions: Internet Gaming Disorder
Interventions: BEHAVIORAL: Indigenously Adapted Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19
Status: RECRUITING
Conditions: COVID-19|Critical Illness|ICU Acquired Weakness|PICS|Cardiorespiratory Fitness
Interventions: BEHAVIORAL: REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Women's Heart Attack Research Program: Stress Ancillary Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction
Interventions: BEHAVIORAL: Enhanced Usual Care|BEHAVIORAL: Stress Management|DIAGNOSTIC_TEST: Actigraph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single vs. Group CAPA-IVM Culture of Cumulus-oocyte Complexes
Status: COMPLETED
Conditions: IVF|PCOS|IVM
Interventions: OTHER: The way of Cumulus-oocyte complexes (COC) culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists
Status: COMPLETED
Conditions: Power|Metabolic Disturbance|Change, Body Weight|Changes Fatty|Muscle Loss|Oxidative Stress|Inflammatory Response|Oxygen Deficiency|Acid-Base Imbalance|Electrolyte Disturbance
Interventions: DIETARY_SUPPLEMENT: 2S-hesperidin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib or Nilotinib Followed by Imatinib in Patients With Newly Diagnosed, Chronic Phase Chronic Myeloid Leukemia
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia|Chronic Myeloid Leukemia|Leukemia
Interventions: DRUG: Dasatinib|DRUG: Imatinib Mesylate|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WORKWELL: Testing Work Advice for People With Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Rheumatoid|Arthritis, Psoriatic|Arthritis, Inflammatory
Interventions: OTHER: WORKWELL|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial to Treat Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DE-112|DRUG: DE-112|DRUG: DE-112|DRUG: DE-112|DRUG: DE-112 Vehicle Solution|DRUG: Timolol Maleate Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Saxagliptin and Dapagliflozin on Endothelial Progenitor Cell in Patients With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Saxagliptin 5mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Single Dose Trial of Empagliflozin in Children and Adolescents With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: empagliflozin medium dose|DRUG: empagliflozin high dose|DRUG: empagliflozin low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer
Status: RECRUITING
Conditions: Adenoid Cystic Carcinoma|Metastatic Adenoid Cystic Carcinoma
Interventions: DRUG: AL101|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Treating Influenza With Liugan Shuangjie Heji
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Liugan Shuangjie Heji|DRUG: Shufeng Jiedu Capsule|DRUG: Oseltamivir Phosphate Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Dienogest 2.0 mg With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Dienogest 2.0 mg Test Drug|DRUG: Dienogest 2.0 mg Reference Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Perioperative Ketamine Infusion on Surgical Recovery
Status: COMPLETED
Conditions: Opioid Use|Enhanced Recovery After Surgery|Anesthesia|Ketamine|Pain, Postoperative
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Intratumoral Washing Fluid for Detecting EGFR Mutations in Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Gene Mutation
Interventions: DIAGNOSTIC_TEST: Ultarthin bronchoscopy with intratumoral washing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CBT Group for Adolescents With ADHD: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Psychopharmacological treatment|BEHAVIORAL: CBT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Education in BRCA Families
Status: ENROLLING_BY_INVITATION
Conditions: BRCA1 Mutation|BRCA2 Mutation
Interventions: BEHAVIORAL: Web + Streamlined Telephone Genetic Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cardiorenal Interactions During Treatment of Acute Decompensated Heart Failure: Diuretics Versus Ultrafiltration
Status: COMPLETED
Conditions: Acute Decompensated Heart Failure
Interventions: PROCEDURE: ultrafiltration|DRUG: diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Movement After ACL Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Knee Osteoarthritis
Interventions: PROCEDURE: Squat Biofeedback|PROCEDURE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation
Status: RECRUITING
Conditions: Airway Management|Respiration, Artificial
Interventions: DEVICE: ADULT Sotair Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Security, Adherence, Tolerability and Cost Effectiveness of Latent TB Treatment in Patients With TB/DM2 (TBL)
Status: COMPLETED
Conditions: Diabetes Mellitus|Tuberculin (Skin Test) Positive
Interventions: DRUG: Isoniazid 300 mg Oral Tablet|DRUG: Rifampin 600 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of an Antibiotic Implant in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection
Status: COMPLETED
Conditions: Cardiac Surgery|Sternal Wound Infection
Interventions: DRUG: gentamicin-collagen sponge dipped in saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lifestyle and Physical Activity as Part Of Obstructive Sleep Apnea Treatment
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Individually tailored lifestyle and physical activity intervention|BEHAVIORAL: Individually tailored lifestyle and physical activity intervention combined with enhanced behavioral support -intervention (EBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DRUG: TAS-303|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Diaphragm Training on Dysphagia in Elderly Nursing Home Residents
Status: NOT_YET_RECRUITING
Conditions: Dysphagia
Interventions: BEHAVIORAL: Diaphragm Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMIC vs. MFx in the Ankle
Status: WITHDRAWN
Conditions: Osteochondral Lesion of Talus|Chondral Defect|Microfracture
Interventions: PROCEDURE: Microfracture (MFx)|DEVICE: Chondro-Gide®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
Status: COMPLETED
Conditions: Uterine Prolapse
Interventions: PROCEDURE: sacral colpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Explorative Study of Treatment of Contact Dermatitis Due to DiabetesDevices
Status: TERMINATED
Conditions: Contact Dermatitis Irritant|Type 1 Diabetes
Interventions: DEVICE: DPLX-PT1|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of GoldenFlow Peripheral Stent System
Status: UNKNOWN
Conditions: Iliac Artery Stenosis|Iliac Artery Occlusion|Femoral Artery Stenosis|Femoral Artery Occlusion|Popliteal Arterial Stenosis|Popliteal Artery Occlusion
Interventions: DEVICE: GoldenFlow Peripheral Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: TSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistant Starch, Antioxidant Status and Insulin Resistance
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Hi-maize resistant starch|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of a Patient Decision Aids for Breast Cancer Screening
Status: UNKNOWN
Conditions: Breast Cancer|Mammary Cancer|Breast Tumor|Mammary Tumor
Interventions: OTHER: Decision aid (DA) for breast cancer screening|OTHER: Standarised information for breast cancer screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized, Single-blinded, Multicenter Trial Comparing the Immune Response to a 2nd Booster Dose of COVID-19 mRNA Vaccine (Pfizer-BioNTech) or Sanofi /GSK B.1.351 Adjuvanted Vaccine in Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Vaccines
Interventions: BIOLOGICAL: 2nd booster with Comirnaty® (Pfizer-BioNTech)|BIOLOGICAL: CoV2 preS dTM adjuvanted vaccine (B.1.351), Sanofi/GSK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect Of Bath Wıth Chlorexıdıne On Protectıon Of Skın Integrıty And Preventıon Of Hospıtal Infectıon
Status: COMPLETED
Conditions: Health Care Associated Infection|Skin
Interventions: OTHER: 2% chlorhexidine digluconate solution|OTHER: usual baths
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial to Assess the Efficacy of Combination Formula of Aspirin Plus Clopidogrel in Patients With Coronary Stent
Status: COMPLETED
Conditions: ANEURYSM CORONARY ARTERY
Interventions: DRUG: Clopirin 1|DRUG: Clopidogrel-Aspirin(co-administration) 1|DRUG: Clopirin 2|DRUG: Clopidogrel-Aspirin(co-administration) 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Efficiency of Two Models of Delivering Care to a Chronic Wound Population
Status: COMPLETED
Conditions: Varicose Ulcer
Interventions: OTHER: Clients randomized to nurse-led clinic|OTHER: Clients receive leg ulcer care in their homes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Slow Expansion and Protraction in Cleft Lip and Palate Patients
Status: UNKNOWN
Conditions: Cleft Lip and Palate
Interventions: DEVICE: Maxillary Expander with Differential Opening (EDO)|DEVICE: Petit face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of the GlaxoSmithKline (GSK) Biologicals' Respiratory Syncytial Virus (RSV) Investigational Vaccine (GSK3003891A) in Healthy Pregnant Women and Infants Born to Vaccinated Mothers
Status: WITHDRAWN
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV vaccine (GSK3003891A) formulation 1|BIOLOGICAL: RSV vaccine (GSK3003891A) formulation 2|BIOLOGICAL: RSV vaccine (GSK3003891A) formulation 3|DRUG: Placebo (Formulation buffer S9b)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebellar Transcranial Direct Current Stimulation (tDCS) in Children With Autism Spectrum Disorder: Raynor Cerebellum Project
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: trans cranial direct current stimulation (tDCS)|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empowering Patients' Lung Cancer Screening Uptake
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Patient education|BEHAVIORAL: Referral to financial navigation resources|BEHAVIORAL: Patient Reminders|BEHAVIORAL: Provider Reminers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Breast Cancer|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Neuroblastoma|Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Afatinib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Radionuclide Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Preconceptional Obesity on the Myometrial Cells Differentiation Toward a Contractyl Phenotype
Status: COMPLETED
Conditions: Pregnancy Complication
Interventions: OTHER: Myometrium biopsy and blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: European/International FMD Registry and Initiative
Status: RECRUITING
Conditions: Fibromuscular Dysplasia
Interventions: GENETIC: Genetic dissection of Fibromuscular Dysplasia|OTHER: Search for diagnostic and prognostic biomarkers of Fibromuscular Dysplasia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Brief Electronic Intervention for Heavy Drinking and Sex Risk Among MSM Seeking HIV Testing
Status: COMPLETED
Conditions: HIV Infections|Alcohol Abuse
Interventions: BEHAVIORAL: Brief Electronic Intervention|BEHAVIORAL: Attention-Matched Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICU
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: BACLOFEN|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ProMIO2.0; A Powerful Lifestyle Intervention for Older Adults From Ethnic Minorities
Status: COMPLETED
Conditions: Sarcopenia|Diabetes|Overweight|Ethnic Minorities|Musculoskeletal Diseases
Interventions: BEHAVIORAL: ProMIO2.0 program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Glucagon In Glucose Control in Cystic Fibrosis Related Diabetes
Status: COMPLETED
Conditions: Cystic Fibrosis|Cystic Fibrosis Related Diabetes
Interventions: OTHER: Oral Glucose Tolerance Test|OTHER: Mixed Meal Tolerance Test|OTHER: Hypoglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Oral HRS5685 in Healthy Subjects
Status: UNKNOWN
Conditions: Human Immunodeficiency Virus-1 (HIV-1) Infection
Interventions: DRUG: HRS5685；Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative
Status: NOT_YET_RECRUITING
Conditions: Mouth Neoplasms
Interventions: PROCEDURE: Sentinel Node Biopsy|PROCEDURE: Limited Elective Neck Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access Protocol
Status: AVAILABLE
Conditions: Neuroblastoma|Childhood Metastatic Pheochromocytoma
Interventions: DRUG: 131 I-Metaiodobenzylguanidine (131 I-MIBG)|DRUG: 131 I-MIBG
Study Type: EXPANDED_ACCESS
Clinical trial: Dietary Intervention of Stress-Induced Neurovegetative Disorders With a Specific Amino Acid Composition (asn01)
Status: COMPLETED
Conditions: Nervous System Disorder|Imbalance of Constituents of Food Intake
Interventions: DIETARY_SUPPLEMENT: amino acid composition (asn01)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Physiological Mechanisms Behind the ObeEnd Device on Factors Regulating Appetite
Status: COMPLETED
Conditions: Healthy Obesity, Metabolically|Obesity
Interventions: DEVICE: ObeEnd Band|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Assess Wound Healing Efficacies of Different Clean, Treat, and Protect Wound Care Regimens Compared to Standard of Care and Untreated
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: SoC Adhesive Bandage|DRUG: Antibiotic Ointment|DRUG: Antiseptic Wash|DEVICE: Hydrocolloid Pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of DECIDE in Patient-Provider Communication, Therapeutic Alliance & Care Continuation
Status: COMPLETED
Conditions: Mental Disorders
Interventions: BEHAVIORAL: DECIDE-PA|BEHAVIORAL: DECIDE-PC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Allopurinol|DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Comprehensive Corrective Exercises Program on Kyphosis in Recreational Cyclists
Status: COMPLETED
Conditions: Thoracic Kyphosis|Cyclists
Interventions: OTHER: Comprehensive Corrective Exercise Program|OTHER: Thoracic Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Adding Weight Control to Smoking Cessation Quitlines
Status: COMPLETED
Conditions: Cigarette Smoking|Overweight|Obesity
Interventions: BEHAVIORAL: Weight gain prevention and smoking cessation|BEHAVIORAL: Smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-site Trial Comparing Lichtensteins Operation and Prolene Hernia System in Inguinal HErnia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Lichtenstein's operation|PROCEDURE: Prolene Hernia System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Two Functional Appliances for Class II Malocclusions
Status: UNKNOWN
Conditions: Malocclusion, Angle Class II
Interventions: DEVICE: Button and Bead appliance|DEVICE: Twin Block appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal Hysterectomy
Status: COMPLETED
Conditions: Ketamine|Anesthesia|Morphine|Hysterectomy
Interventions: DRUG: Esketamine|DRUG: Saline|DRUG: Remifentanil|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DRUG: Hydroxychloroquine lower dose|DRUG: Hydroxychloroquine higher dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Procyanidin B2 Enriched Cocoa Effects on Mitochondrial Biogenesis
Status: COMPLETED
Conditions: Athletes
Interventions: DIETARY_SUPPLEMENT: procyanidin B2 enriched cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mandibular Overdentures Retained by Conventional or Mini Implants
Status: COMPLETED
Conditions: Edentulous Mouth|Edentulous Jaw
Interventions: DEVICE: Implant-retained mandibular overdenture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Of A Single PF-04634817 Tablet Dose Compared With A Solution In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-04634817|DRUG: PF-04634817
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate Use of Induced Skin Blisters in Adult Participants With Atopic Dermatitis, Allergic Asthma and Atopic Healthy Participants
Status: COMPLETED
Conditions: Dermatitis, Atopic|Asthma|Healthy
Interventions: OTHER: Allergic Skin Reaction (ASR) Testing and Skin Blister Induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Ventilator Associated Pneumonia|Nursing Caries|Aspiration, Respiratory
Interventions: DEVICE: Smart Cuff Manager|DEVICE: Manometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Scintigraphy Study in Healthy Volunteers to Characterize the Performance of ALLN-346 Tablets
Status: COMPLETED
Conditions: Hyperuricemia|Gout
Interventions: DRUG: Each ALLN-346 treatment will be radiolabelled to contain 4 MBq 99mTc at time of dosing with light meal|DRUG: Each ALLN-346 treatment will be radiolabelled to contain 4 MBq 99mTc at time of dosing in fasted/fed state
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AGILE (Early Phase Platform Trial for COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: Covid19
Interventions: DRUG: CST-2: EIDD-2801|DRUG: CST-2: Placebo|DRUG: Nitazoxanide|DRUG: VIR-7832|DRUG: VIR-7831|DRUG: CST-5: Placebo|DRUG: Favipiravir|DRUG: Molnupiravir|DRUG: Paxlovid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Of GSK189075 Taken By Mouth Containing Small Amounts Of Radioactivity Studied In Healthy Male Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Radiolabelled GSK189075
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fiber Fermentation, and Short Chain Fatty Acid Kinetics and Utilization Inside the Gut and Systemic Circulation
Status: UNKNOWN
Conditions: Dietary Fiber
Interventions: DIETARY_SUPPLEMENT: fructo- and galacto-oligosaccharides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Study of the HIV Drug CPT31 in Healthy Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CPT31|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain
Status: RECRUITING
Conditions: HIV Infections|Obesity
Interventions: DRUG: Biktarvy|DRUG: Symtuza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of SBRT With Concurrent Ipilimumab in Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Effects of Immunotherapy|Adverse Effect of Radiation Therapy
Interventions: RADIATION: Stereotactic body radiotherapy (SBRT)|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise on Quality of Life, Sleep Quality and Anxiety in Patients With Prediabetes (EFEXQULS)
Status: UNKNOWN
Conditions: PreDiabetes|Physical Inactivity|Quality of Life|Sleep|Anxiety|Depression
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Comparing SG301 Plus Pomalidomide and Dexamethasone to Placebo Plus Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma Patients
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: SG301 Injection|DRUG: SG301 placebo|DRUG: pomalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study by Scintigraphy to Evaluate the Effect of Exenatide on Gastric Emptying in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide and placebo|DRUG: Exenatide and placebo|DRUG: Exenatide and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm
Interventions: RADIATION: Total-Body Irradiation|PROCEDURE: Donor Lymphocyte Infusion|DRUG: Cyclophosphamide|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Versus Delayed FET Following a Stimulated IVF Cycle
Status: COMPLETED
Conditions: Fertilization in Vitro|Embryo Transfer
Interventions: OTHER: immediate frozen-thawed embryo transfer|OTHER: delayed frozen-thawed embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Assess Safety, Tolerability, PD, PK, Immunogenicity of IV NTR-441 Solution in Healthy Volunteers and COVID-19 Patients
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: NTR-441|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of PermeaDerm® (PD) as Compared to Mepilex Ag®
Status: UNKNOWN
Conditions: Thermal Burn
Interventions: DEVICE: PermeaDerm®|DEVICE: Mepilex Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Vasodilatory Effect of GLP-1
Status: COMPLETED
Conditions: Coronary Stenosis|Type2 Diabetes|Angina, Stable
Interventions: DRUG: GLP-1 (7-36)Amide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Three Techniques for Ultrasound Guided Axillary Brachial Plexus Block
Status: UNKNOWN
Conditions: Hand Surgery
Interventions: PROCEDURE: Axillary brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effects of Enclomiphene Citrate on Bone Mineral Density in Men With Secondary Hypogonadism
Status: COMPLETED
Conditions: Effect of Treatment on Bone Mineral Density
Interventions: DRUG: enclomiphene citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: TACE With or Without SBRT as Bridging Therapy for Pre-transplant HCC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: TACE transarterial chemoembolization|RADIATION: stereotatic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-251 in Participants With Duchenne Muscular Dystrophy Amenable to Exon 51 Skipping
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy (DMD)
Interventions: DRUG: DYNE-251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4D Motion of the Aorta in the Chest and Simulated Wall Stress Distribution in Relation to Aortic Events
Status: UNKNOWN
Conditions: Aortic Dissection
Interventions: DIAGNOSTIC_TEST: multiphase ECG-gated contrast-enhanced CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rate of Left Ventricular Systolic Function's Recuperation After Cardiac Surgery With Extracorporeal Circulation.
Status: WITHDRAWN
Conditions: Myocardial Stunning|Transesophageal Echocardiography|Circulation, Extracorporeal
Interventions: DEVICE: Imacor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain
Status: NOT_YET_RECRUITING
Conditions: Symptomatic Irreversible Pulpitis
Interventions: DRUG: Trypsin, Bromelain and Rutoside|DRUG: Diclofenac Potassium|DRUG: Prednisolone Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of BTDS in Subjects With Osteoarthritic (OA) Pain of Hip or Knee: A 6-Month Open-label Extension Phase
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch|DRUG: Buprenorphine transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation by Zinc Supplementation in Children With Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Children, Only
Interventions: DRUG: Zinc sulfate|OTHER: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) as an add-on Therapy for Treatment of Major Depressive Disorder. (DEPTDCS2014)
Status: UNKNOWN
Conditions: Depression
Interventions: DEVICE: Sooma tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ramosetron on Bowel Motility After Gynecological Surgery
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ramosetron|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infections, Recurrent
Interventions: DIETARY_SUPPLEMENT: HA 100 mg, CS 400 mg, N-Acetylglucosamine 200 mg and vitamin C 80 mg + cranberry, D-mannose, propolis extract, tumeric and Boswellia|DIETARY_SUPPLEMENT: cranberry, D-mannose, propolis extract, tumeric and Boswellia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab in Chinese Participants With Systemic Juvenile Idiopathic Arthritis (sJIA)
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab|DRUG: NSAIDs|DRUG: CSs|DRUG: MTX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial Evaluating Safety and Tolerability of CAIV-T in Healthy Japanese Male Adults
Status: COMPLETED
Conditions: Healthy Japanese Male Adults
Interventions: BIOLOGICAL: CAIV-T|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients
Status: TERMINATED
Conditions: Liver Transplantation|Metabolic Syndrome X|Obesity
Interventions: OTHER: Control group|OTHER: Mediterranean diet|OTHER: Protein-Sparing Modified Fast (PSMF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary|Idiopathic Pulmonary Fibrosis|Cystic Fibrosis|Bronchiectasis|Pulmonary Vascular Disease
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: EZ-2053|BIOLOGICAL: EZ-2053 5mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide and Cyclophosphamide in Treating Patients With Previously Treated Hormone-Refractory Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer
Interventions: DRUG: lenalidomide|DRUG: cyclophosphamide|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease
Status: COMPLETED
Conditions: Dementia Associated With Cerebrovascular Disease
Interventions: DRUG: Donepezil hydrochloride|DRUG: Donepezil matching placebo|DRUG: Donepezil hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Wearable Activity Tracker in Elderly Undergoing Abdominal Surgery
Status: UNKNOWN
Conditions: Fitness Trackers|Early Ambulation|Surgery|Health Services for the Aged
Interventions: DEVICE: Fitbit Zip Activity Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Placebo|DRUG: MBX-8025|DRUG: MBX-8025|DRUG: Atorvastatin|DRUG: MBX-8025|DRUG: MBX-8025
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Assessing the Safety, Tolerability, and Pharmacokinetics of Intravenous AZD5099 in Healthy Subjects
Status: SUSPENDED
Conditions: Healthy
Interventions: DRUG: AZD5099|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE