pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study About the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: OTHER: Remedial treatment within 3 months|OTHER: Remedial treatment within 3 to 6 months|OTHER: Remedial treatment within 6 to 12 months|OTHER: Remedial treatment after 12 months
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: Optune®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Procedure Pulmonary Artery Denervation in Addition to Pulmonary Vein Isolation Combined With Ganglionated Plexi Ablation in Patients With Persistent Atrial Fibrillation and Pulmonary Hypertension
Status: UNKNOWN
Conditions: Atrial Fibrillation|Hypertension, Pulmonary|Heart Diseases|Arrhythmias, Cardiac|Pathologic Processes|Cardiovascular Diseases|Lung Diseases
Interventions: PROCEDURE: PV isolation + GP Ablation|PROCEDURE: PV isolation + GP ablation + Pulmonary GP ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Plus Anlotinib for the Maintenance of Extensive Stage Small Cell
Status: NOT_YET_RECRUITING
Conditions: SCLC|Maintenance Treatment
Interventions: DRUG: Toripalimab plus Anlotinib|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: 30 mg letrozole followed by 800 mcg misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Unilateral Balance Training Among Athletes With Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Injuries|Ankle Sprains
Interventions: PROCEDURE: Balance Exercise Training for Stable Ankle|PROCEDURE: Balance Exercise Training for Unstable Ankle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interaction of Docetaxel and Lonafarnib in Patients With Advanced Cancer
Status: TERMINATED
Conditions: Lung Cancer|Soft Tissue Sarcoma|Colorectal Carcinoma|Breast Cancer|Prostate Cancer
Interventions: DRUG: Lonafarnib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator-Associated Pneumonia
Interventions: DEVICE: Bronchoalveolar lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prospective, Single-blind Study Assessing the Benefit/Risk Ratio of Internal Limiting Membrane (ILM) Peeling During Epimacular Membrane (EMM) Surgery (Peeling)
Status: COMPLETED
Conditions: Idiopathic Epimacular Membrane
Interventions: PROCEDURE: ILM Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling
Status: RECRUITING
Conditions: Dementia|Alzheimer Disease|Dementia With Lewy Bodies|Vascular Dementia|Frontotemporal Dementia|Mild Cognitive Impairment|Corticobasal Syndrome|Progressive Supranuclear Palsy|Parkinson Disease|Primary Progressive Aphasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beta Blocker Use In Traumatic Brain Injury Based On The High-Sensitive Troponin T Status
Status: RECRUITING
Conditions: Trauma|Brain Injuries|Stress Reaction|Beta Blockers|Troponin
Interventions: DRUG: Placebo|DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Applying Additional Weight on Crouch Gait in Children With Spastic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Gait, Spastic|Motor Disorders|Functional Neurological Disorder
Interventions: OTHER: Applying additional weight
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Pyrotinib in HR-positive and HER2-low High-risk Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer Invasive|Hormone-receptor-positive Breast Cancer|HER2 Low Breast Carcinoma|Early-stage Breast Cancer
Interventions: DRUG: Pyrotinib, epirubicin or doxorubicin, cyclophosphamide, paclitaxel|DRUG: Epirubicin or doxorubicin, cyclophosphamide, paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketones and Muscle Protein Synthesis
Status: COMPLETED
Conditions: Ketosis|Regulation of Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Ketone|DIETARY_SUPPLEMENT: Ketone + Protein|DIETARY_SUPPLEMENT: Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Eplerenone to Improve Target Organ Damage in Patients With Resistant Arterial Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: placebo|DRUG: eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An International, Multicenter, Randomized, Double-Blind, Double-Masked Study of the Efficacy and Safety of BCD-132 (JSC BIOCAD, Russia) Using an Active Reference Drug (Teriflunomide) for the Treatment of Patients With Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: BCD-132|DRUG: Teriflunomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC
Status: RECRUITING
Conditions: Oligometastatic Disease|Non-small Cell Lung Cancer|Driver Mutation
Interventions: RADIATION: Local Consolidative Radiation Therapy|DRUG: TKI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Therapy Dog Activity on Employees' Stress, Mood, and Job Satisfaction and Commitment
Status: WITHDRAWN
Conditions: Stress|Mood|Job Satisfaction
Interventions: BEHAVIORAL: Therapy dog activity|BEHAVIORAL: Low impact exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combining Wearable Technology to Crate Internet+Digital Hospital-remote Home Type 2 Diabetes Follow-up Management Mode
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Remote monitoring devices+Internet management platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Activity Changes Following Neuroproprioceptive Physiotherapy in Multiple Sclerosis
Status: COMPLETED
Conditions: Neuronal Plasticity|Multiple Sclerosis|Rehabilitation
Interventions: BEHAVIORAL: Motor Program Activating Therapy|BEHAVIORAL: Vojta reflex locomotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Transdermal Clonidine Administrations in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Catapres-TTS-1|DRUG: Intervention 1: Catapres-TTS-3|DRUG: Intervention 1: Catapres-TTS-3|DRUG: Intervention 2: Catapres-TTS-3|DRUG: Catapres-TTS-1|DRUG: Intervention 2: Catapres-TTS-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria
Status: TERMINATED
Conditions: Serious Bacterial Infection
Interventions: COMBINATION_PRODUCT: ATM-AVI|DRUG: BAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth
Status: NOT_YET_RECRUITING
Conditions: Necrotic Pulp
Interventions: OTHER: Root canal irrigant Commiphora Myrrh 50%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of IMO on Intestinal Microbiota Translocation in Cirrhosis
Status: RECRUITING
Conditions: Decompensated Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Isomaltooligosaccharides (IMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Response Evaluation of Cancer Therapeutics in Metastatic Breast Cancer to the Bone: A Whole Body MRI Study
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DIAGNOSTIC_TEST: Computerised Tomography|DIAGNOSTIC_TEST: Whole Body Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Bone scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Liraglutide|OTHER: Exercise training|DRUG: Liraglutide + Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Disparities in Myocardial Infarction Remodeling According to Gender
Status: RECRUITING
Conditions: Myocardial Infarction|Ventricular Remodeling
Interventions: DIAGNOSTIC_TEST: cardiac imaging to assess left ventricular volumes and function
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Frontal Stimulation to Modulate Threat Sensitivity in Anxious Depression
Status: COMPLETED
Conditions: Depression|Anxiety and Fear
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor
Status: RECRUITING
Conditions: Neoplasms|Tenosynovial Giant Cell Tumor
Interventions: DRUG: ABSK021
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy-Induced Immune Modulation: Part III
Status: COMPLETED
Conditions: Actinic Keratosis|Photodynamic Therapy
Interventions: DRUG: Celecoxib 200mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Erectile Dysfunction I
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Udenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Anaesthesia vs. General Anaesthesia for THA, TKA and UKA
Status: RECRUITING
Conditions: Osteoarthritis, Hip|Osteoarthritis, Knee
Interventions: DRUG: Spinal anesthesia|DRUG: General anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Neurobehavioral Outcomes Follow-up in Primary CNS Lymphoma Patients Treated With Cranial Radiotherapy Combined With or Without MTX-based Chemotherapy According to the Multidisciplinary Treatment Guidelines Implemented at a Single Institute
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: RADIATION: Standard treatment protocol with combined chemoradiation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Alcohol-related Attitudinal and Behavioural Change Amongst Adolescents Through Internet Intervention
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice|Drinking Behaviour
Interventions: BEHAVIORAL: Interactive health promotion|BEHAVIORAL: Passive health promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Budesonide Intrapolyp Injection in the Management of Type 2 Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Budesonide|DRUG: Prednisone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Stimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Caloric Vestibular Stimulation|DEVICE: Sham Caloric Vestibular Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon Alfa-2a Plus Low Dose Ribavirin for Treatment-Naïve Hemodialysis Patients With Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a and ribavirin|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT
Status: NOT_YET_RECRUITING
Conditions: Periodontal Pocket
Interventions: PROCEDURE: PHOTODYNAMIC THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)|Chronic Lymphocytic Leukemia (CLL)|Chemotherapy-sensitive Lymphoma|Acute Lymphoblastic Leukemia (ALL)/T Lymphoblastic Lymphoma|Acute Myelogenous Leukemia (AML)|Acute Biphenotypic Leukemia (ABL)|Acute Undifferentiated Leukemia (AUL)
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide 14.5 mg/kg/day IV on Days -6, -5|RADIATION: Total Body Irradiation (TBI) 200cGy on Day -1|PROCEDURE: Infusion of non-T-cell depleted bone marrow on Day 0|DRUG: Busulfan|DRUG: Cyclophosphamide 50mg/kg/day IV on Days -2,-1|DRUG: Cyclophosphamide 50mg/kg/day IV on Days -5,-4|RADIATION: Total Body Irradiation (TBI) 200cGy twice a day on Days -3, -2, -1|DRUG: Post-HCT Cyclophosphamide 50mg/kg IV on Day+3, +4|DRUG: Sirolimus|DRUG: Mycophenolate mofetil|DRUG: G-CSF|DRUG: Pre-HCT Mesna on Days -6 and -5|DRUG: Pre-HCT Mesna on Days -2 and -1|DRUG: Pre-HCT Mesna on Days -5 and -4|DRUG: Post-HCT Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Synbiotic Supplement on the Body Mass Index of Participants With Severe Obesity
Status: UNKNOWN
Conditions: Obesity Class III
Interventions: DIETARY_SUPPLEMENT: Synbiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Richter Syndrome|Small Lymphocytic Lymphoma|Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma|Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Duvelisib|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapse Prophylaxis With N-803 for AML and MDS Pts Following Allo HSCT
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia (AML)|Myelodysplastic Syndrome (MDS)
Interventions: DRUG: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Tissue Engineering (Nanostructured Artificial Human Cornea) in Patients With Corneal Trophic Ulcers in Advanced Stages, Refractory to Conventional (Ophthalmic) Treatment
Status: COMPLETED
Conditions: Severe Trophic Corneal Ulcers Refractory to Conventional Treatment|Sequelae of Previous Trophic Corneal Ulcers
Interventions: DRUG: Anterior lamellar nanostructured artificial human cornea.|OTHER: Amniotic membrane transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Transversalis Versus Transversus Abdominis Plane Block for Children Undergoing Inguinal Hernia Surgery
Status: RECRUITING
Conditions: Fascia Transversalis Plane Block
Interventions: PROCEDURE: Ultrasound- guided Fascia Transversalis plane block|PROCEDURE: Ultrasound-guided Transversus abdominus plane block|DRUG: Fentanyl|DRUG: Pethidine|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ESP Block vs Control for Pain Control Following Percutaneous Nephrolithotomy
Status: RECRUITING
Conditions: Nephrolithotomy, Percutaneous
Interventions: PROCEDURE: Erector Spinae Plane Block|DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ciprofloxacin on Burned Patients
Status: COMPLETED
Conditions: Burns|Bacterial Infections
Interventions: DRUG: Ciprofloxacin (BAYO9867)|DRUG: Ciprofloxacin (BAYO9867)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of Different Regimens of Indacaterol
Status: COMPLETED
Conditions: Persistent Asthma
Interventions: DRUG: Indacaterol|DRUG: Placebo to Indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zimmer POLAR Persona - TKA (EMEA Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Knee Pain|Severe Knee Disability|Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Polyarthritis
Interventions: DEVICE: Zimmer Persona Total Knee System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: CLN-617|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous and Subcutaneous Secukinumab in Moderate to Severe Chronic Plaque-type Psoriasis
Status: COMPLETED
Conditions: Plaque-type Psoriasis
Interventions: DRUG: secukinumab 150mg|DRUG: secukinumab 10mg/kg i.v. regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cladribine Tablets on the PK of Microgynon®
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis (RMS)
Interventions: DRUG: Cladribine|DRUG: Placebo|DRUG: Microgynon®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Efficacy Study of Aclasta on Prosthetic Fixation in Postmenopausal Women After THA
Status: WITHDRAWN
Conditions: Prosthetic Fixation After Cementless Total Hip Arthroplasty
Interventions: DRUG: Zoledronic acid 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fresh Frozen Plasma as a Substitute for Albumin in Patients Receiving a Large Volume Paracentesis
Status: WITHDRAWN
Conditions: Liver Cirrhosis|Ascites Hepatic
Interventions: BIOLOGICAL: Fresh Frozen Plasma (FFP)|BIOLOGICAL: Albumin|PROCEDURE: Large Volume Paracentesis (LVP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYT003 in Patients With Mild to Moderate Allergic Asthma Not Sufficiently Controlled on Inhaled Glucocorticosteroids
Status: WITHDRAWN
Conditions: Asthma
Interventions: BIOLOGICAL: CYT003|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Most Closely Human Leukocyte Antigen (HLA)-Matched BK Virus-specific T Lymphocytes (Viralym-B)
Status: WITHDRAWN
Conditions: BK Virus Infection
Interventions: BIOLOGICAL: Viralym-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|OTHER: Placebo|BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: STrategies for Catheter Ablation of peRsistent Atrial Fibrlllation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Wide Circumferential Pulmonary Vein Antrum Isolation (PVAI)|PROCEDURE: Pulmonary Vein Antrum Isolation Plus Driver Ablation (PVAI+drivers)|PROCEDURE: Pulmonary Vein Antrum Isolation Plus Box Isolation of Posterior Wall (PVAI+box)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RAD001 and Sunitinib in Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Kidney Cancer
Interventions: DRUG: RAD001, Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Lower-body Negative Pressure in Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: OTHER: Lower-body Negative Pressure (-25 mmHg)|OTHER: Lower-body Negative Pressure (-15 mmHg)|OTHER: Lower-body Neutral Pressure (0 mmHg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Retreatments With Intravitreal Bevacizumab
Status: TERMINATED
Conditions: Age Related Macular Degeneration|Choroidal Neovascularization
Interventions: DRUG: Intravitreal injection of Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Community Delivery of Malaria Intermittent Preventive Treatment on Pregnant Women and Babies
Status: COMPLETED
Conditions: Malaria in Pregnancy
Interventions: BEHAVIORAL: Community distribution of SP for IPTp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Polyphenols From Milk and Dark Chocolate
Status: COMPLETED
Conditions: No Disease
Interventions: DIETARY_SUPPLEMENT: Dark Chocolate|DIETARY_SUPPLEMENT: Milk Chocolate|DIETARY_SUPPLEMENT: Control (polyphenol-free) "Chocolate"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Effectiveness and Safety of Xa Inhibitor for the Prevention of Stroke And Systemic Embolism in a Nationwide Cohort of Japanese Patients Diagnosed as Non-valvular Atrial Fibrillation
Status: UNKNOWN
Conditions: Non-valvular Atrial Fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Adult Synovial Sarcoma|Childhood Hepatoblastoma|Childhood Synovial Sarcoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Adrenocortical Carcinoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive|Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Recurrent Retinoblastoma|Recurrent Wilms Tumor and Other Childhood Kidney Tumors
Interventions: BIOLOGICAL: cixutumumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperopia|High Astigmatism
Interventions: DEVICE: Fresh Corneal Lenticule Implantation using Relex-Smile VisuMax Femtosecond Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Ultrasound Treatment of Chronic Wounds With Monitoring of Healing and Quality of Life Outcomes
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer|Venous Ulcer
Interventions: DEVICE: Low Frequency, Low Intensity Ultrasound|DEVICE: Sham Applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Multi Radiance Medical® Super Pulsed Laser on Chronic Knee Pain
Status: RECRUITING
Conditions: Knee Pain Chronic
Interventions: DEVICE: Placebo Multi Radiance Medical® Super Pulsed Laser|DEVICE: Active Multi Radiance Medical® Super Pulsed Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Folic Acid in Levodopa Treated Parkinson's Disease Patients
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Folic Acid Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Bilateral Implantation of an Enhanced Monofocal Intraocular Lens
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: ICB00 IOL|DEVICE: ZCB00 IOL|DEVICE: CNA0T0 IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Web-Based Weight Loss & Weight Maintenance Intervention for Older Rural Women, Also Known as Women Weigh-in for Wellness
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: Experimental: Web-based only (WO) weight intervention|BEHAVIORAL: Experimental: WO plus peer-led discussion board (WD)|BEHAVIORAL: Experimental: WO & professional email counseling (WE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Lung Transplant HCV, Pilot Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Transplant Infection|Hepatitis C
Interventions: DRUG: Sofosbuvir-velpatasvir (400 mg/100 mg)|DEVICE: Ex Vivo Lung Perfusion (EVLP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism
Status: RECRUITING
Conditions: Autism|Autism Spectrum Disorder|ASD
Interventions: BEHAVIORAL: Center-Based Pivotal Response Treatment (PRT) Intervention (PRT-C)|BEHAVIORAL: Home-Based Pivotal Response Treatment (PRT Intervention (PRT-H)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Amlodipine and Losartan in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Amlodipine plus Losartan|DRUG: Amlodipine|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of the Anterior Cruciate Ligament of the Knee Joint, by the Method of Stabilization of the Screw With a Bioabsorbable Method, With or Without the Use of Autogenous Spongiform Bone Grafts.
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|Knee Injuries|Knee Ligament Injury
Interventions: PROCEDURE: ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) with the use of autogenous cancellous bone grafts|PROCEDURE: ACL reconstruction of the knee joint by arthroscopic technique, with the tibial fixation method using a bioabsorbable screw (Arthrex) without the use of autogenous cancellous bone grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Efficacy and Pharmacokinetics of MICARDIS® (Telmisartan) in Children and Adolescents With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Studying the Effectiveness of Non-Invasive Glucose Sensors in Patients With Diabetes: The SENSOR Study
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Wearing a non-invasive glucose sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Brief Writing Programs for Sexual Minority Young Adults in Alabama
Status: WITHDRAWN
Conditions: Expressive Writing|Self-Affirmation|Control
Interventions: BEHAVIORAL: Expressive Writing|BEHAVIORAL: Self-Affirmation|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Muscle Coordination-Based Feedback for Stroke Rehabilitation
Status: ENROLLING_BY_INVITATION
Conditions: Stroke
Interventions: DEVICE: Conventional High Intensity Gait Training|DEVICE: Standard FES to the Tibialis Anterior (TA)|DEVICE: Synergy-Based Multichannel FES (MFES)|DEVICE: Muscle Synergy Visual Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RCT of CBD for Anxiety in Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Breast Cancer|Anxiety|CBD
Interventions: DRUG: Cannabidiol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Wrist Splint and Occupational Therapy to Improve Pain, Mobility and Functional Status in Patients With Wrist Drop
Status: RECRUITING
Conditions: Wrist-Drop
Interventions: DIAGNOSTIC_TEST: Wrist Splint|DIAGNOSTIC_TEST: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
Status: NOT_YET_RECRUITING
Conditions: Wound; Head, Multiple|Wound; Head, Scalp|Wound; Head|Wound Infection|Wound Complication|Wound Dehiscence|Wound of Skin|Wound Open|Wounds, Penetrating|Wounds, Nonpenetrating|Wounds and Injuries|Wounds|Disturbance of Wound Healing|Facial Bones Fracture|Soft Tissue Injuries|Skull Fractures|Surgical Wound|Surgical Wound Infection|Wound Healing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial of Protein and Blood Pressure
Status: COMPLETED
Conditions: Hypertension|Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Soy protein-milk protein-carbohydrate|DIETARY_SUPPLEMENT: Milk protein-carbohydrate-soy protein|DIETARY_SUPPLEMENT: Carbohydrate-soy protein-milk protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence
Status: COMPLETED
Conditions: Breast Cancer With Low to Intermediate HER2 Expression
Interventions: BIOLOGICAL: NeuVax™ vaccine|BIOLOGICAL: Leukine® (sargramostim, GM-CSF) and water for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline Therapy
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Bevacizumab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEPCAD I. The Paclitaxel-Eluting PTCA-Balloon Catheter to Treat Small Vessel
Status: COMPLETED
Conditions: Coronary Stenosis
Interventions: DEVICE: Drug Eluting Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Mass Index and Obesity Surgery Mortality Risk Score in Perioperative Complications of Laparoscopic Sleeve Gastrectomy
Status: COMPLETED
Conditions: Perioperative Complication|Laparascopic Sleeve Gastrectomy|BMD|Obesity, Morbid|Obesity Surgery Mortality Score|Clavien Dindo Surgical Complication Scale
Interventions: PROCEDURE: Laparascopic Sleeve Gastrectomy|PROCEDURE: İnterventional radiologic drainage|DIAGNOSTIC_TEST: Complte Blood Count and Biochemical evaluation|DIAGNOSTIC_TEST: Computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of a Lactobacillus Strain on the Prevention of Recurrent Vaginal Candidiasis
Status: UNKNOWN
Conditions: Recurrent Vulvovaginal Candidiasis
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Lactobacillus strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 44847 Powder in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 44847|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation in Patients With Interstitial Lung Disease
Status: COMPLETED
Conditions: Interstitial Lung Disease
Interventions: OTHER: NMES Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Levels of Pain, Discomfort, and Functional Impairment With Two Techniques of Retraction
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: DEVICE: Mini-implants|DEVICE: Transpalatal arche (TPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Inflation Methods of Ambú Auragain™ and Its Adverse Effects
Status: COMPLETED
Conditions: Laryngeal Mask Airway
Interventions: PROCEDURE: Intracuff pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapy
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Cobimetinib|DRUG: Idasanutlin|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Comparing A New 80 Mg Atorvastatin Tablet To A 80 Mg Atorvastatin Commercial Tablet
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin|GENETIC: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intranasal Dexmedetomidine Versus Intranasal Midazolam for Emergence Delirium Prevention
Status: COMPLETED
Conditions: Emergence Delirium
Interventions: DRUG: Intranasal dexmedetomidine|DRUG: Intranasal Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: METR-NK cell(Metabolic Remodeling Nature Killer Cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Predictive Hypoglycaemia Alert Function in Physical Activity for People With T1DM
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DEVICE: Dexcom G6 with alert|DEVICE: Dexcom G6 without alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis
Status: COMPLETED
Conditions: Central Serous Chorioretinitis
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Static Stretching and Dynamic in Flexibility and Performance: Blind and Randomized Clinical Trial
Status: COMPLETED
Conditions: Neuromuscular Manifestations
Interventions: OTHER: intervention with static stretching|OTHER: intervention with Dynamic Stretching|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy
Status: RECRUITING
Conditions: Esophagus Cancer
Interventions: PROCEDURE: Catheterization|PROCEDURE: Single nerve block|PROCEDURE: Continuous nerve block|PROCEDURE: PCIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY
Status: SUSPENDED
Conditions: Wound Healing
Interventions: PROCEDURE: coronally advanced flap with subepithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy and Myocardial Recovery in Heart Failure Patients Undergoing Left Ventricular Assist Device Support
Status: RECRUITING
Conditions: Heart Failure|Mechanical Circulatory Support
Interventions: BIOLOGICAL: CD34+ stem cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pan-T Booster Co-expressing MSLN CAR T Cell Therapy in Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: BIOLOGICAL: Pan-T booster co-expressing MSLN CAR T cell|DRUG: Albumin-bound paclitaxel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas Patients
Status: RECRUITING
Conditions: Soft-tissue Sarcoma|Predictive Cancer Model
Interventions: OTHER: Care with the use of PERSARC|OTHER: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single Ascending Doses of CC-92480 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: CC-92480|DRUG: CC-92480
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing and Reducing Risk of Violent Re-Injury Among Victims of Urban Violence
Status: UNKNOWN
Conditions: Violence
Interventions: BEHAVIORAL: Motivational Interviewing|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of the GOLO for Life® Plan With Release Supplement on Glycemic Control and Weight in Overweight and Obese Adults With Prediabetes or Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Obese|Overweight|Prediabetes
Interventions: DIETARY_SUPPLEMENT: Release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Cognitive Training and Rhythmic Auditory Stimulation in Treadmill Training After Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Combined group|DEVICE: Cognitive group|DEVICE: Rhythmic group|DEVICE: Treadmill group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcranial Oscillatory Direct Current Stimulation on the Functions of Cerebral Cortex in Healthy Subjects
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Motor Evoked Potential|Healthy Subjects
Interventions: DEVICE: toDCS 2mA 1Hz|DEVICE: toDCS 2mA 10Hz|DEVICE: tDCS 1mA|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab in Combination With Bortezomib and Dexamethasone in Newly Diagnosed Transplant Ineligible Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleeve Gastrectomy for Morbid-Obesity Sequelae After Transplantation
Status: NOT_YET_RECRUITING
Conditions: Liver Transplantation|Obesity
Interventions: PROCEDURE: Sleeve gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT