pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of Turoctocog Alfa (N8) in Prevention and On-demand Treatment of Bleeding Episodes in Subjects With Haemophilia A: An Extension to Trials NN7008-3543, NN7008-3545, NN7008-3600, NN7008-3893 and NN7008-4015
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: turoctocog alfa|DRUG: turoctocog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Low Level Laser Light Therapy on Improving the Symptoms of Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DEVICE: Erchonia ALS Laser|DEVICE: Placebo Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Oral Cyclophosphamide, and Dexamethasone for RRMM
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: DRUG: Carfilzomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the May Health Device in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With PCOS Infertility
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DEVICE: May Health Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Highly Accelerated Dose-Integrated Radiotherapy in 5 Fractions in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Radiotherapy
Interventions: RADIATION: Dose-integrated accelerated EBRT in pN0 breast cancer|RADIATION: Dose-integrated accelerated EBRT in pN+ breast cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CDCA in CTX Chenodeoxycholic Acid (CDCA) in Patients Affected by Cerebrotendinous Xanthomatosis (CTX)
Status: COMPLETED
Conditions: Cerebrotendinous Xanthomatoses
Interventions: DRUG: Chenodeoxycholic Acid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Efficacy of Oxyjun on Cardiovascular Health in Healthy Individuals.
Status: COMPLETED
Conditions: Cardiovascular Health
Interventions: OTHER: Oxyjun|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Folic Acid Administration in the Progression of Microalbuminuria
Status: COMPLETED
Conditions: Diabetic Nephropathies|Hyperhomocysteinemia
Interventions: DRUG: Folic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endogenous vs. Exogenous Ketone Bodies
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Beta-Hydroxybutyrate as Ca-Mg-salt, active|DIETARY_SUPPLEMENT: ketogenic diet (KetoCal® 4:1 Neutral, Nutricia GmbH, Erlangen, Germany), active|DIETARY_SUPPLEMENT: fasting, active|DIETARY_SUPPLEMENT: fasting, inactive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antioxidant Supplement and Reduction of Metachronous Adenomas of the Large Bowel: a Double Blind Randomized Trial
Status: TERMINATED
Conditions: Colorectal Adenomas
Interventions: DRUG: antioxidants|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Autonomic Profiles in Pediatric Patients With Cyclic Vomiting Syndrome (CVS), Irritable Bowel Syndrome (IBS),Postural Orthostatic Tachycardia Syndrome (POTS), Functional Abdominal Pain (FAP) or Chronic Nausea
Status: COMPLETED
Conditions: Vomiting Syndrome|Irritable Bowel Syndrome|Postural Orthostatic Tachycardia Syndrome|Abdominal Pain|Chronic Nausea
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of CC-292 and Rituximab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Leukemia Lymphocytic Chronic B-Cell
Interventions: DRUG: CC-292|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T&B Depletion Non Malignant
Status: UNKNOWN
Conditions: Graft Versus Host Disease
Interventions: BIOLOGICAL: polyclonal antibody|DRUG: Rituximab|DRUG: Treosulfan|DRUG: Fludarabine|DRUG: Thiotepa|DRUG: Cyclosporine A|DRUG: Methotrexate|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Short Term Outcomes of Robotic-assisted Intersphincteric Resection for Low Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DEVICE: Robot-assisted surgery|DEVICE: Laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine Extended Release(ER)in Patients With Overactive Bladder.
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Tolterodine ER|DRUG: Placebo|DRUG: Fesoterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent and Adjuvant PD1 Treatment Combined With Chemo-radiotherapy for High-risk Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Cancer|Chemotherapy|Radiotherapy|PD-1 Therapy
Interventions: DRUG: Camrelizumab plus chemo-radiotherapy|DRUG: Chemo-radiotherapy alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Anti-CFA/I and CfaE Bovine Milk Immunoglobulin Against Challenge With H10407 ETEC Expressing CFA/I
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: anti-CFA/I bovine IgG, and anti-CfaE bovine IgG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Daclatasvir (BMS-790052) With Telaprevir Combined With Peginterferon Alfa-2a and Ribavirin in Patients With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Daclatasvir|DRUG: Telaprevir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: General Anesthesia With Xenon in Inspiratory Concentrations of 50% and 70% and Total I.V. Anaesthesia.
Status: TERMINATED
Conditions: Anaesthesia
Interventions: DRUG: Xenon|DRUG: Xenon|DRUG: Medical Air in Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of Aleeto in Amyotrophic Lateral Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Aleeto|DEVICE: intravenous injection|DEVICE: intrathecal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Blood Management Charité (PBM-Charité): Structured Detection, Differentiated Diagnostics and Therapy of Preoperative Anemia and Use of Machine Autotransfusion in Elective Interventions
Status: RECRUITING
Conditions: Anemia
Interventions: OTHER: BARMER anemia treatment|OTHER: NON-BARMER anemia treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Description of the Ability to Learn How to Handle Inhaler Devices in Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DEVICE: placebo Diskus®|DEVICE: placebo Ellipta®|DEVICE: Pulmicort® Turbuhaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Psilocybin in Adults With and Without Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Psilocybin 5 mg|DRUG: Psilocybin 2 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trauma Management Therapy for OEF and OIF Combat Veterans
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Combat Disorders
Interventions: BEHAVIORAL: 17 week Exposure Therapy Control Arm|BEHAVIORAL: Trauma Management Therapy|BEHAVIORAL: Intensive 3-Week Trauma Management Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod Tablets Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD).
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: losmapimod|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trigger Point Therapy Versus Manipulation Correcting Thoracic Manipulable Lesion
Status: UNKNOWN
Conditions: Spinal Manipulable Lesion|Somatic Dysfunction
Interventions: PROCEDURE: spinal manipulation|PROCEDURE: trigger point therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Intrathecal Morphine Induced Pruritus: Comparison of Ondansetron and Palonosetron
Status: COMPLETED
Conditions: Morphine Adverse Reaction
Interventions: DRUG: Ondansetron|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CyFluATG in Lower Risk MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: cyclophosphamide, fludarabine, and antithymocyte globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone to Treat Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DRUG: Oral administration of mifepristone 2.5 mg daily for three months|DRUG: Oral administration of mifepristone 5 mg daily for three months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Photodynamic Therapy + Aflibercept vs. Afilbercept Alone for PDA in NV AMD
Status: WITHDRAWN
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Aflibercept|DRUG: Triamcinolone Acetonide|DRUG: Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants With Early Alzheimer's Disease (Polaris-AD)
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: AR1001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALX-0171 Phase I Pharmacokinetic Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy|RSV Infection
Interventions: BIOLOGICAL: ALX-0171|BIOLOGICAL: ALX-0171|BIOLOGICAL: ALX-0171
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Limb Injuries and Post Injury Rehabilitation Trials - Tibial Shaft Fracture
Status: RECRUITING
Conditions: Tibia Fracture
Interventions: PROCEDURE: Full weight-bearing|PROCEDURE: Partial weight-bearing|PROCEDURE: Intramedullary nailing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Effectiveness of Brain-computer Interface-pedaling Training System on the Rehabilitation of Stroke
Status: COMPLETED
Conditions: Rehabilitation|Stroke|Brain-computer Interface
Interventions: DEVICE: Brain-computer Interface-Pedaling Training System|DEVICE: Traditional Pedaling Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate the Safety and Efficacy of Cannabidiol Oral Solution (GWP42003-P; CBD-OS) in Children and Adolescents With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: GWP42003-P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Supplementation in Shigella Patients
Status: COMPLETED
Conditions: Testing Effect of Intervention
Interventions: DRUG: Children in the zinc group received 20 mg of elemental zinc as acetate per day in a twice-daily dose for two weeks.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Changes in Specific Immunoglobulin and Blood Basophil Activity During Subcutaneous Immunotherapy in Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Alutard phleum pratense subcutaneous immunotherapy|DRUG: Alutard phl prat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pectin Intervention Study and Long-term Follow-up in Lipid Transfer Proteins Allergic Patients
Status: NOT_YET_RECRUITING
Conditions: Food Allergy
Interventions: DIETARY_SUPPLEMENT: Apple pectin (DE 57%)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water- and Salt-homeostasis in Healthy Humans, and in Patients With Heart- or Lung Disease
Status: UNKNOWN
Conditions: Healthy Volunteers|Heart Failure|Aortic Stenosis|Ischemic Heart Disease|Pulmonary Hypertension
Interventions: DRUG: Pharmacologic and mechanical heart failure treatment|PROCEDURE: Aortic valve replacement|PROCEDURE: Revascularisation in Acute Coronary Syndrome|PROCEDURE: Revascularisation in chronic stable angina pectoris
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CHG Dressings in Children With Central Lines
Status: TERMINATED
Conditions: Children With Central Venous Access
Interventions: OTHER: Tegaderm CHG clear dressing|OTHER: Standard clear Tegaderm dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Acute Post-stroke Oropharyngeal Dysphagia With Paired Stimulation
Status: RECRUITING
Conditions: Stroke|Stroke, Acute|Oropharyngeal Dysphagia|Swallowing Disorder
Interventions: COMBINATION_PRODUCT: Piperine 150μM + tDCS 2mA|COMBINATION_PRODUCT: Piperine 1mM + tDCS 2mA|COMBINATION_PRODUCT: Capsaicin 10μM + tDCS 2mA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Optimal Timing of Postoperative Radiotherapy in Patients With IIIA(N2) Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer Stage IIIA|Radiotherapy
Interventions: RADIATION: PORT-first|RADIATION: PORT-last|DRUG: Platinum-based two drug chemotherapy (cisplatin/carboplatin + vinorelbine or cisplatin/carboplatin + pemetrexed regimen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Elidel (Pimecrolimus) 1% Cream to Treat Netherton Syndrome
Status: COMPLETED
Conditions: Netherton Syndrome
Interventions: DRUG: Pimecrolimus 1% Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintaining Cochlear Patency After VIIIth Nerve Surgery
Status: WITHDRAWN
Conditions: Acoustic Neuroma|Labyrinthitis Ossificans|Profound Hearing Impairment
Interventions: DEVICE: MedEl Test Electrode Placer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of the Recombinant Human Bovine Reassortant Rotavirus Vaccine in Healthy Indian Infants
Status: WITHDRAWN
Conditions: Rotavirus Infections
Interventions: BIOLOGICAL: Live Attenuated Tetravalent (G1-G4) Bovine-Human Reassortant Rotavirus Vaccine [BRV-TV]|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: APC-231 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) in Pediatric Patients With Strep Throat
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Amoxicillin Pulsatile Release Multiparticluate Sprinkle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Icg's Route of Administration During Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Laparoscopic; Cholecystectomy|Cholelithiasis; Bile Duct|Choledocholithiasis|Stone - Biliary|Post-Op Complication|Cholangiography|Indocyanine Green|Intraoperative Complications|Bile Duct Injury
Interventions: PROCEDURE: Indocyanine Green (ICG) administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Steroid Combination in Ocular Trauma (ASCOT) Study
Status: COMPLETED
Conditions: Eye Injury Trauma
Interventions: DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast-enhanced Ultrasound With Perfluorobutane and Sulfur Hexafluoride for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DIAGNOSTIC_TEST: contrast enhanced ultrasound|DIAGNOSTIC_TEST: Dynamic CT|DIAGNOSTIC_TEST: Liver MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Radiculopathy Lumbar
Interventions: PROCEDURE: non-pharmacological treatment|PROCEDURE: pharmacological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Radionuclide Imaging|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MitoQ for Fatigue in Multiple Sclerosis (MS)
Status: RECRUITING
Conditions: Multiple Sclerosis|Fatigue
Interventions: DRUG: 20 mg MitoQ|DRUG: Placebo|DRUG: 40mg of MitoQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MBT in Groups for Adolescents With BPD or Subthreshold BPD Versus TAU - the M-GAB Randomized Controlled Trial
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: Mentalization Based Treatment|BEHAVIORAL: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Bioequivalence of Two Fixed Dose Combination (FDC) Tablet Formulations of Amlodipine and Losartan FDC5/50 and FDC5/100 Under Fasting Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Reference Treatment: 5 mg amlodipine + 50 mg losartan|DRUG: Reference Treatment:5 mg amlodipine + 100 mg losartan|DRUG: FDC 5/50 amlodipine/ losartan|DRUG: FDC 5/100 amlodipine /losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary|HIV/AIDS
Interventions: DRUG: RIPE (2m) and RI (4m)|DRUG: RIPE+NAC (2m) and RI (4m)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of [18F]PMPBB3 and [18F]THK5351 PET Distribution Patterns on Post-stroke Cognitive Impairment
Status: RECRUITING
Conditions: Post-stroke Cognitive Impairment|Neuroinflammation
Interventions: DRUG: PMPBB3|DRUG: THK5351
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Failing Blebs With Ranibizumab
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Failing Bleb Following Trabeculectomy
Interventions: DRUG: Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Automatic Image Fusion of a CT Volume With Ultrasound During Percutaneous Ablation Treatment of Hepatic Tumors
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Interact Active Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BMS-986278|DRUG: BMS-986278 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance
Status: COMPLETED
Conditions: Sleep Disturbance
Interventions: BEHAVIORAL: Spanish-language Cognitive-Behavioral Therapy for Insomnia (CBT-I) delivered via videoconference
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Behavior Change and Maintenance Intervention for HIV+ MSM Methamphetamine Users
Status: COMPLETED
Conditions: HIV Infections|Substance Abuse|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: EDGE counseling, no maintenance|BEHAVIORAL: EDGE counseling, plus maintenance|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Biomechanical Reappraisal of Planning for Thoracic Endovascular Aortic Repair
Status: UNKNOWN
Conditions: Thoracic Aortic Aneurysm|Aortic Dissection|Aortic Diseases
Interventions: DIAGNOSTIC_TEST: TEVAR patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketogenic Diet vs.Antiepileptic Drug Treatment in Drug Resistant Epilepsy
Status: UNKNOWN
Conditions: Epilepsy|Mental Retardation
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DRUG: Antiepileptic drug (AED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ILX23-7553 in Treating Patients With Solid Tumors That Have Not Responded to Previous Therapy
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: vitamin D3 analogue ILX23-7553
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: bcr-abl p210-b3a2 breakpoint-derived multipeptide vaccine|BIOLOGICAL: sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulative Treatment in Individuals With Temporomandibular Disorder Who Make Use of Occlusal Splints
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Osteopathic Manipulative Treatment|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Placebo|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Misoprostol Before Endometrial Biopsy
Status: COMPLETED
Conditions: Endometrial Biopsy
Interventions: DRUG: misoprostol|DRUG: vitamin B6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ReNu™ vs. Corticosteroids for the Treatment of Plantar Fasciitis
Status: UNKNOWN
Conditions: Fasciitis, Plantar
Interventions: OTHER: ReNu Injection|OTHER: Corticosteroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Physical Training in Patients With Chronic Obstructive Pulmonary Disease Patients
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Physical Training|BEHAVIORAL: Cognitive-Physical Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: RT+CDDP/5-FU|DRUG: RT+CETUXIMAB|DRUG: INDUCTION CTx(TPF)+(RT+CDDP/5-FU)|DRUG: INDUCTION CTx(TPF)+(RT+CETUXIMAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B-SAFER: Branched Stented Anastomosis Frozen Elephant Trunk Repair
Status: RECRUITING
Conditions: Thoracic Aortic Aneurysm|Aortic Dissection|Congenital Aortic Anomaly
Interventions: DEVICE: B-SAFER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Noninferiority of Medicines Treating Uninfected Pressure Ulcers.
Status: WITHDRAWN
Conditions: Pressure Ulcer
Interventions: DRUG: Collagenase|DRUG: Kollagenase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise, Milk Thistle, and Lactobacillus to Influence Plasma Bilirubin
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Milk Thistle (MT)|DIETARY_SUPPLEMENT: Lactobacillus Gasseri (LAC)|BEHAVIORAL: Exercise (EX)|DIETARY_SUPPLEMENT: Control (CON)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Sedation Protocol for Endoscopic Procedures Using Impedance Ventilation Monitor.
Status: RECRUITING
Conditions: Sedation Complication|Ventilatory Depression
Interventions: DRUG: Sedation using only Propofol.|DRUG: Sedation using combination of Propofol and Fentanyl.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Digital Diabetes Remission Trial
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2
Interventions: COMBINATION_PRODUCT: Digital therapeutic and intensive lifestyle programme|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Ovarian Function Suppression + Aromatase Inhibitor|DRUG: Adjuvant Chemotherapy + Ovarian Function Suppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Technique, Open Versus Minimally-invasive Gastrectomy After CHemotherapy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Minimally-invasive gastrectomy|PROCEDURE: Open Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maraviroc to Augment Rehabilitation Outcomes After Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Maraviroc 300 mg|BEHAVIORAL: Rehabilitation therapy|DRUG: Placebo 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Different Music Genres on Heart Rate Variability in Extremely and Very Low Birth Weight Newborns
Status: COMPLETED
Conditions: Infant Behavior|Infant Conditions|Infant Morbidity
Interventions: BEHAVIORAL: The influence of different music genres on Heart Rate Variability (HRV) in preterm infants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Levalbuterol and Racemic Albuterol in Pediatric Subjects With Reactive Airways Disease (RAD)
Status: COMPLETED
Conditions: Reactive Airways Disease (RAD)
Interventions: DRUG: Levalbuterol HCl Inhalation Solution|DRUG: Levalbuterol HCl Inhalation Solution|DRUG: Albuterol HCl Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Valsartan Based Versus an Amlodipine Based Treatment Strategy in naïve Patients With Stage 1 or Stage 2 Hypertension or in Patients Uncontrolled on Current Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Nabumetone 750 mg Tablets of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nabumetone|DRUG: Relafen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Efficacy of a One-Session Mindfulness Telehealth Intervention for Loneliness
Status: COMPLETED
Conditions: Loneliness
Interventions: BEHAVIORAL: Mindfulness Alone (MO) Intervention|BEHAVIORAL: Mindfulness + Compassion Intervention (MC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Biomarker Study of Standard-of-care Radium-223 Chloride for Metastatic Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer|Castration-resistant Prostate Cancer Metastatic to Bone
Interventions: PROCEDURE: Blood Tests|PROCEDURE: CT scan|PROCEDURE: FACBC PET/MRI in a subset of participants|DRUG: Radium-223 dichloride|PROCEDURE: bone scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of RIPC to Reduce AKI for Patients Undergoing PCI
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Sham remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Pharmacokinetic Properties of Biphasic Insulin Aspart 50 in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 50
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on the Efficacy of tDCS) in Reducing Alcohol Consumption in Non-abstinent Patients (REDSTIM)
Status: COMPLETED
Conditions: Alcoholic Intoxication, Chronic
Interventions: DEVICE: Active tDCS|DEVICE: Placebo tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-controlled Clinical Trial of Teneligliptin as Quadruple Oral Combination Therapy for Type 2 DM After Failure of an Oral Triple Anti-diabetic Regimen
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: teneligliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Passive Heat Therapy on Oxygen Consumption and Cardiovascular Fitness in Adults
Status: COMPLETED
Conditions: Heart Failure|Heart Diseases|Cardiovascular Diseases|Endothelial Dysfunction
Interventions: BEHAVIORAL: Heat Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety of Ropivacaine TAP Block Combined With Intravenous Lidocaine in Patients Undergoing Colorectal Cancer Surgery
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Ropivacaine Hydrochloride 10 MG/ML [Naropin]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: BAY2416964|DRUG: BAY2416964
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Neuroblastoma|Stage 2A Neuroblastoma|Stage 2B Neuroblastoma|Stage 3 Neuroblastoma|Stage 4 Neuroblastoma|Stage 4S Neuroblastoma
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effect of Hydroxyethyl Starch (HES) in Complications of Patients After Abdominal Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: Hydroxyethyl Starch 130/0.4 (Voluven)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Nivolumab in Combination With EGF816 and of Nivolumab in Combination With INC280 in Patients With Previously Treated Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: EGF816|DRUG: INC280|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: oxaliplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SKIN WHEAL - Subcutaneous or Intradermal Lidocaine in Epidural for Laboring Pain.
Status: RECRUITING
Conditions: Analgesia, Obstetrical
Interventions: PROCEDURE: 1% Lidocaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®
Status: COMPLETED
Conditions: Growth Hormone Deficiency|Turner Syndrome
Interventions: DRUG: Saizen|DRUG: Saizen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Achilles Tendon Lengthening in Patients With Diabetes to Prevent Foot Ulcers
Status: COMPLETED
Conditions: Diabetes Mellitus|Foot Ulcer|Peripheral Neuropathy
Interventions: PROCEDURE: Achilles tendon-lengthening surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.
Status: COMPLETED
Conditions: HSIL of Cervix|HSIL, High Grade Squamous Intraepithelial Lesions|High-Grade Cervical Intraepithelial Neoplasia|Human Papilloma Virus|HIV Negative|Cervical Cancer|CIN - Cervical Intraepithelial Neoplasia|Cervical Neoplasm|Cervical Dysplasia
Interventions: DRUG: Topical ABI-1968
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Homogenization and Pasteurization of Milk on the Stomach Problems in Adults
Status: COMPLETED
Conditions: Unidentified Stomach Discomfort Following Dairy Consumption
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness Based Cognitive Therapy Modified for Visual Symptoms (MBCT-vision)
Status: COMPLETED
Conditions: Visual Snow Syndrome|Trailing Phenomenon|Photophobia|Visual Aura
Interventions: BEHAVIORAL: Mindfulness Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Hypoglycemic Counter Regulatory Responses in Type 1 Diabetics vs Control Subjects
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus, Type 1
Interventions: OTHER: Glucose clamp technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Emend and Ondansetron Compared to Ondansetron Alone to Prevent CINV in Glioma Patients Receiving Temozolomide
Status: COMPLETED
Conditions: Nausea|Vomiting|Glioma
Interventions: DRUG: aprepitant|DRUG: ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DRUG: Methoxsalen +ECP|PROCEDURE: Extracorporeal Photopheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Broccoli Seed and Sprout Extract for Detoxification of Carcinogens in Firefighters
Status: SUSPENDED
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|DIETARY_SUPPLEMENT: Broccoli Sprout/Broccoli Seed Extract Supplement|DRUG: Placebo Administration|OTHER: Questionnaire Administration|OTHER: Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Evaluate the Short Time Efficacy of AP Green Tea Extract Affer High Fat, High Carbohydrate Diet
Status: COMPLETED
Conditions: Blood Glucose, High
Interventions: DIETARY_SUPPLEMENT: AP green tea extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus
Status: COMPLETED
Conditions: Renal Transplanted Recipients
Interventions: DRUG: Everolimus (RAD001)|DRUG: Cyclosporine (Calcineurin Inhibitor (CNI))|DRUG: Methylprednisone/prednisone|DRUG: Mycophenolate sodium (MPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boiled Peanut Immunotherapy for the Treatment of Peanut Allergy
Status: ACTIVE_NOT_RECRUITING
Conditions: IgE Mediated Peanut Allergy|Peanut Hypersensitivity
Interventions: OTHER: Boiled peanut|OTHER: Defatted roasted peanut flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: JNJ-42847922|DRUG: Placebo Matching to JNJ-42847922|DRUG: Quetiapine XR|DRUG: Placebo Matching to Quetiapine XR|DRUG: Selective Serotonin Reuptake Inhibitor (SSRI)|DRUG: Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pathogenesis of Functional Hypothalamic Amenorrhea
Status: COMPLETED
Conditions: Disorder of Endocrine Ovary|Hypersecretion; Cortisol|Metabolic Disturbance|Stress, Psychological
Interventions: BEHAVIORAL: Cognitive behavior therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascia Iliaca Block Versus Intravenous Dexmedetomidine and Ketamine for Positioning Fracture Femur
Status: RECRUITING
Conditions: Pain|Analgesia
Interventions: DEVICE: ultrasound guided facia iliaca block|DRUG: Intravenous drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Grey Zone Appendicitis: Role of Blood Test Biomarkers to Detect Early Appendicitis and to Decrease the Incidence of Negative Appendectomy
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Center Randomized Controlled Trial Assessing Pain and Quality of Life Following Surgery
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: Flexible Fiber-based CO2 Laser, Quality of Life forms|OTHER: electrocautery resection and quality of life forms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 6-week Safety and PD Study in Adults With NAFLD
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Placebo|DRUG: PF-06835919 Low Dose|DRUG: PF-06835919 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Water Immersion and Water Exchange Methods During Minimally Sedated Colonoscopy
Status: COMPLETED
Conditions: Colon Neoplasm|Pain
Interventions: PROCEDURE: air insufflation|PROCEDURE: water immersion|PROCEDURE: water exchange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC