pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of a Web-based Decision Aid Tool for Larynx Cancer (T3/T4) Patients.
Status: COMPLETED
Conditions: Larynx Cancer
Interventions: OTHER: Interviews|OTHER: Treatmentchoice Decisional Tool|OTHER: Questionnaires|OTHER: Interviews with stakeholders
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Chronic Ischemic Heart Disease|Heart Failure|Angina
Interventions: BIOLOGICAL: UCMSC group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Low Dose and High Dose Intra-articular Tranexamic Acid in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine patch - transdermal|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CMP-001 in Combo With Nivolumab in Stage IIIB/C/D Melanoma Patients With Clinically Apparent Lymph Node Disease
Status: COMPLETED
Conditions: Melanoma|Lymph Node Cancer
Interventions: DRUG: CMP-001|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AND017 to Treat Anemia in Non-dialysis-Dependent Chronic Kidney Disease (NDD-CKD) Patients
Status: COMPLETED
Conditions: Renal Anemia
Interventions: DRUG: AND017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Atorvastatin (Lipitor) to Decrease Panel Reactive Antibody Titers
Status: COMPLETED
Conditions: End-Stage Kidney Disease
Interventions: DRUG: Atorvastatin (Lipitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High-precision Transcranial Direct Current Stimulation on Anxiety Disorders
Status: NOT_YET_RECRUITING
Conditions: Anxiety Disorders|High-definition Transcranial Direct Current Stimulation
Interventions: OTHER: High-definition transcranial direct current stimulation|OTHER: High-definition transcranial direct current stimulation pseudo-stimulation control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Multi-centre, Extension Study to Investigate the Long Term Safety of ONO-2506PO in Patients Diagnosed With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis (ALS)
Interventions: DRUG: ONO-2506PO
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Perampanel Administered as an Adjunctive Therapy in Pediatric Participants With Childhood Epilepsy
Status: RECRUITING
Conditions: Pediatric Epileptic Syndrome|Partial-onset Seizures
Interventions: DRUG: Perampanel Oral Suspension|DRUG: Perampanel Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Activity of Intravenous (IV) ABBV-383 Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: ABBV-383|DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Elotuzumab|DRUG: Selinexor|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Factors Associated With Sleep Disorders in Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Crohn Disease|Ulcerative Colitis|Sleep Disorder
Interventions: OTHER: Ulcerative colitis Disease Activity Index
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FNB in Meniscal Tear Under SA
Status: NOT_YET_RECRUITING
Conditions: Meniscus Tear|Femoral Nerve Block
Interventions: PROCEDURE: Sono-guided injection|DRUG: Ropivacaine injection|DRUG: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: IMU-838 tablets|DRUG: Placebo matching IMU-838 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 0.2% Hyaluronic Acid Gel-Impregnated Dental Flosses on Clinical Gingival Parameters
Status: COMPLETED
Conditions: Gingivitis
Interventions: DEVICE: Dental floss+Gengigel|DEVICE: Dental Floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Substudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Quavonlimab|BIOLOGICAL: Vibostolimab|DRUG: Lenvatinib|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Seven-Week Dose-Ranging Study of CP-526,555 Compared With Placebo and Zyban for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: CP-526,555 (varenicline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators
Status: RECRUITING
Conditions: Colorectal Cancer|Breast Cancer
Interventions: BEHAVIORAL: Time-Restricted Eating (TRE)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-dimer In Patients With atRial Fibrillation rEceiving antiCoagulation Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation|Strokes Thrombotic
Interventions: DRUG: Dabigatran Etexilate 110mg|DRUG: Warfarin Sodium
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Modulation of Fibrosis-inducing Pathways in Acute Myocardial Infarction
Status: RECRUITING
Conditions: Myocardial Infarction|Myocardial Fibrosis|Myocardial Remodeling, Ventricular
Interventions: DRUG: P2Y12 Potent Inhibitor + Aspirin for STEMI patients|DRUG: Clopidogrel + Aspirin for CCS patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of 10-gram Collagen Protein Hydrolysate on Cardiometabolic Health
Status: COMPLETED
Conditions: Glucose Metabolism|Lipid Metabolism
Interventions: DIETARY_SUPPLEMENT: 10 g of collagen hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: TH-302 Plus Doxorubicin Delivered by Trans-Arterial Chemoembolization (TACE) in Patients With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Phase I Dose level -1|DRUG: Phase I dose level 1|DRUG: Phase I Dose level 2|DRUG: Phase I Dose level 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The HERCULES Trial - A Safety and Effectiveness Study of the Herculink Elite Renal Stent to Treat Renal Artery Stenosis
Status: COMPLETED
Conditions: Renal Artery Obstruction|Hypertension, Renal
Interventions: DEVICE: Herculink Elite Renal Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Pirfenidone for BOS After HCT
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Graft Vs Host Disease
Interventions: DRUG: Pirfenidone 267 MG [Esbriet]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training and Detraining Effects of a Physical Activity Program Implemented Through Mobile Applications in Adolescents.
Status: COMPLETED
Conditions: Adolescent Behavior|Mobile Applications|Physical Activity|Physical Condition|Body Composition
Interventions: BEHAVIORAL: The use of mobile applications promoted from the physical education classroom to improve adolescent health.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Wrist Stabilizing Exercise Versus Hand Orthotic Intervention for Persons With Hypermobility
Status: COMPLETED
Conditions: Musculoskeletal Diseases|Joint Instability
Interventions: OTHER: Static strength training program or/and Dynamic strength training program of the hand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Almonertinib Versus Placebo as Adjuvant Therapy in Resected Stage II-IIIB Non-Small Cell Lung Cancer With EGFR-sensitive Mutations
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Almonertinib|DRUG: Placebo Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor
Status: RECRUITING
Conditions: Tremor, Limb
Interventions: DRUG: Abobotulinum toxin A|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Degree of Rice-polishing on Glycaemic Response
Status: COMPLETED
Conditions: Diabetes Mellitus|Obesity
Interventions: OTHER: Glucose Reference 1|OTHER: Glucose Reference 2|OTHER: Glucose Reference 3|OTHER: Brown Rice|OTHER: 3 % polished rice|OTHER: 6 % polished rice|OTHER: 9 % polished rice|OTHER: 20 % Polished rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Drug Concentration Analysis of Micafungin in Overweight, Obese, and Extremely Obese Volunteers
Status: COMPLETED
Conditions: Obesity|Nutrition Disorders|Overweight
Interventions: DRUG: Micafungin|DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Health Promotion Program for Persons With Severe Mental Illness
Status: COMPLETED
Conditions: Evaluate the Effects of an Oral Health Promotion Program
Interventions: BEHAVIORAL: a composite intervention with both group and individual components for oral health promotion program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab in Combination With Chemotherapy in the Neo-adjuvant Setting for HER2 (-) Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Bevacizumb|DRUG: 5-Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Oral NNZ-2591 in Phelan-McDermid Syndrome (PMS-001)
Status: COMPLETED
Conditions: Phelan-McDermid Syndrome
Interventions: DRUG: NNZ-2591
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Does Implementing a GetUp Assist Device in Addition to a Daily Low-intensity Functional or Traditional Training Program Affect Norwegian Female Office Workers' Physical Health After 12 Weeks?
Status: RECRUITING
Conditions: Neck, Shoulder and Arm Syndrome
Interventions: OTHER: Experimental, comparator and control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function
Status: RECRUITING
Conditions: Exercise Performance|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Mitochondrial Substrate Supplement|DIETARY_SUPPLEMENT: Placebo Supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study BT7480-100 in Patients With Advanced Malignancies Associated With Nectin-4 Expression
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: BT7480|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD)
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: mycophenolate mofetil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mild Water-Filtered Near Infrared Whole-Body-Hyperthermia as an Adjunct in the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Iratherm® 1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of a Once-Daily CLS001 Topical Gel Versus Vehicle
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: CLS001 (Omiganan)|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Sodium Zirconium Cyclosilicate on the Pharmacokinetics of Tacrolimus and Cyclosporin in Healthy Subjects
Status: COMPLETED
Conditions: Hyperkalaemia
Interventions: DRUG: Tacrolimus|DRUG: Cyclosporin|DRUG: Sodium Zirconium Cyclosilicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled-Feeding Study to Assess the Effect of Cashews on Fasting Lipoprotein Levels
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Cashews followed by Control|OTHER: Control followed by Cashews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Modified Stem Cells (SB623) in Patients With Chronic Motor Deficit From Ischemic Stroke
Status: COMPLETED
Conditions: Chronic Ischemic Stroke
Interventions: BIOLOGICAL: SB623 Implant (2.5M)|BIOLOGICAL: SB623 Implant (5.0M)|PROCEDURE: Sham surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Chemotherapy and ASCT or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-cell-lymphoma
Interventions: DRUG: Arm A (Fortecortin®-ETOPOPHOS®-IFO-cell®-CARBO-cell®)|DRUG: Arm B (TEPADINA®-CARMUBRIS®-Busilvex®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repurposing Chlorpromazine in the Treatment of Glioblastoma
Status: UNKNOWN
Conditions: Glioblastoma Multiforme|MGMT-Unmethylated Glioblastoma
Interventions: DRUG: Chlorpromazine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial
Status: RECRUITING
Conditions: Osteomyelitis Tibia|Tibial Fractures|Open Tibia Fracture
Interventions: DRUG: Antibiotic coated intramedullary Nail|OTHER: Standard Intramedullary Nail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Prospective Study Comparing Different Clinical Decision Rules in Adult and Pediatric Ankle Trauma
Status: UNKNOWN
Conditions: Ankle Injuries
Interventions: PROCEDURE: Ottawa Ankle and Foot Rules|PROCEDURE: Buffalo Rule|PROCEDURE: Ottawa Ankle and Foot Rules + application of a tuning fork to the distal fibula and tibia|PROCEDURE: Thompson Test|PROCEDURE: Palpation of the fibula|PROCEDURE: Ottawa Ankle and Foot Rules + palpation of the cuboid bone|PROCEDURE: Ottawa Ankle and Foot Rules + palpation over the deltoid ligament|PROCEDURE: Malleolar Zone Algorithm|PROCEDURE: Low Risk Exam|PROCEDURE: Bernese Ankle Rules|PROCEDURE: Ottawa Ankle and Foot Rules + swelling of the distal fibula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study Investigating the Impact of Different IOL Designs on Subjective 2D and 3D Image Quality
Status: COMPLETED
Conditions: Lenses|Intraocular Sensitivity|Visual Acuity
Interventions: DRUG: Cyclopentolatehydrochloride 0,5% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HOME-CoV: Hospitalization or Outpatient ManagEment of Patients With a SARS-CoV-2 Infection
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: OTHER: HOME-CoV rule implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Immune Response of a Meningococcal Conjugate Vaccine Administered to Healthy Adolescents
Status: COMPLETED
Conditions: Prevention of Meningococcal Disease
Interventions: BIOLOGICAL: MenACWY-CRM conjugate vaccine, adjuvanted|BIOLOGICAL: MenACWY-CRM conjugate vaccine, unadjuvanted|BIOLOGICAL: MenACWY polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluating the Pharmacokinetics, Safety, and Efficacy of ATG 016 Monotherapy in IPSS-R Intermediate Risk and Above Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: ATG-016
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutrition Product Combine With Continuous Glucose Monitoring in Gestational Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: SANZ®KINGWILL Combined With CGM Equipment in GDM Patients|GLUCERNA SR® Combined With CGM Equipment in GDM Patients
Interventions: DIETARY_SUPPLEMENT: SANZ®KINGWILL|DIETARY_SUPPLEMENT: GLUCERNA SR®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pistachios and Neural Macular Pigment
Status: RECRUITING
Conditions: Macular Degeneration|Retinal Degeneration|Retinal Diseases|Eye Diseases
Interventions: DIETARY_SUPPLEMENT: Pistachio Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial of Thalidomide Combined With Concurrent Chemoradiotherapy in Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: OTHER: chemoradiotherapy|DRUG: thalidomide|OTHER: without thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD)
Status: COMPLETED
Conditions: Marijuana Abuse
Interventions: DRUG: AEF0117|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Protection of RIPC in Pediatric Living Donor Liver Transplantation
Status: COMPLETED
Conditions: Hepatic Ischemic and Reperfusion Injury
Interventions: DEVICE: remote ischemic preconditioning(RIPC)|DEVICE: Sham RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Salbutamol Facilitate Management of Hyperkalemia Postreperfusion During Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: DRUG: salbutamol|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combating Maternal Mortality in Uganda: An Assessment of the Role of Misoprostol in Prevention of Post-Partum Hemorrhage
Status: COMPLETED
Conditions: Post Partum Hemorrhage
Interventions: DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Treatment of EC Followed by Taxane +/- Carboplatin in Triple-Negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: DRUG: Epirubicin plus Cyclophosphamide|DRUG: Taxanes|DRUG: Taxanes plus Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Quality of Life and Self-sufficiency of Individuals With Stoma: Pecha Kucha Training Via Smartphone
Status: RECRUITING
Conditions: Ostomy
Interventions: OTHER: pecha kucha education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of a Stigma Reduction Intervention for Human Immunodeficiency Virus (HIV)-Infected Women
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)|Self-efficacy|Self-esteem
Interventions: BEHAVIORAL: Ipod video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Opioid Analgesia on Circulating Tumor Cells in Laparoscopic Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Cancer|Circulating Tumor Cell
Interventions: DRUG: Morphine|DRUG: Piritramid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regenerative Surgical Treatment of Peri-implantitis Using Nanobone With or Without Simvastatin
Status: COMPLETED
Conditions: Peri-Implantitis
Interventions: OTHER: bone substitute; NanoBone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multilevel, Multiphase Optimization Strategy for PrEP (MOST:PrEP)
Status: ENROLLING_BY_INVITATION
Conditions: HIV Seropositivity
Interventions: BEHAVIORAL: Computer-based simulation training for providers|BEHAVIORAL: Best Practice Alert|BEHAVIORAL: HIV Risk Assessment|BEHAVIORAL: PrEP Informational Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Inhibition of Spore Production in Patients With C. Difficile Infections: Fidaxomicin Versus Vancomycin
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Vancomycin|DRUG: Fidaxomicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HKT-500 in the Treatment of Adult Patients With Ankle Sprain
Status: COMPLETED
Conditions: Ankle Sprain
Interventions: DRUG: Ketoprofen Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Trial for a Rabies Vaccine (Vero Cell) for Human Use in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Changchun Werersai|BIOLOGICAL: Jilin Maifeng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Olaptesed pegol|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cerebrolysin and Neurodevelopment in Preterm Infants
Status: COMPLETED
Conditions: Infant Development|Cerebral Palsy|Preterm Infant
Interventions: DRUG: Cerebrolysin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
Status: TERMINATED
Conditions: Freeman-Sheldon Syndrome|Arthrogryposis Distal Type 2A|Whistling Face Syndrome|Craniocarpotarsal Dysplasia|Craniocarpotarsal Dystrophy|Freeman-Sheldon Syndrome Variant|Sheldon-Hall Syndrome|Arthrogryposis Distal Type 2B|Gordon Syndrome|Arthrogryposis Distal Type 3|Arthrogryposis Distal Type 1|Arthrogryposis, Distal, Type 1A|Arthrogryposis Distal Type 1B|Arthrogryposis, Distal|Craniofacial Abnormalities|Arthrogryposis
Interventions: OTHER: PTSD Checklist-Civilian (PCL-C)|OTHER: Modified Flanagan Quality of Life Scale|OTHER: Center for Epidemiologic Studies Depression Scale (CES-D)|OTHER: Functional Enquiry (or Review of Systems) Form|OTHER: Study of Therapeutic Outcomes and Practices in Freeman-Sheldon Syndrome (STOP-FSS) Questionnaire|OTHER: FSRG Semi-Structured Quality of Life Interview (FSRG SSQLI)|OTHER: Medical Records Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of the Validity of a Questionnaire to Assess the Visual Function of Preverbal Children With Operable Bilateral Ocular Pathologies
Status: RECRUITING
Conditions: Eye Diseases|Vision Disorders
Interventions: OTHER: Questionnaire for visual function assessment of preverbal children
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer
Status: TERMINATED
Conditions: Oropharynx Cancer|Hypopharynx Cancer
Interventions: DRUG: Homeodent®|DRUG: 1.4% Sodium Bicarbonate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open-label, Single Dose, Parallel Design, Phase 1 Clinical Study of LCB01-0371
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Group 1:LCB01-0371|DRUG: Group 2:LCB01-0371
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response and General Immune Health in Subjects Infected With Herpes Simplex Virus Type 1 (HSV-1)
Status: COMPLETED
Conditions: HSV|Herpes Labialis
Interventions: DRUG: Squaric Acid Dibutyl Ester
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Propofol Induction's Effect on Cardiac Function
Status: COMPLETED
Conditions: This Study Was Focused to Evaluate Feasibility of Doppler Tissue Monitoring During the Induction Anesthesia,|and Evaluate Routine Propofol Induction's Effect on Myocardial Tissue Motion, Using Non-invasive Doppler Tissue and 2D Speckle Tracking Imaging.|This is the First Study, to Our Knowledge, Which Has Evaluated the Possible Impact of Propofol Induction on LV Function.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia
Status: COMPLETED
Conditions: Analgesia|Labor Pain
Interventions: DRUG: Hydromorphone|DRUG: Sufentanil|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Neural Mobilization and Muscle Energy Technique in Sciatic Patients
Status: UNKNOWN
Conditions: Acute Sciatica|Pain
Interventions: OTHER: Neural mobilization|OTHER: Muscle energy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DHP1401 in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil(DRAMA)
Status: COMPLETED
Conditions: Mild-moderate Alzheimer's Disease
Interventions: DRUG: Donepezil|DRUG: DHP1401|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Utero Alcoholic Exposure: PlGF, Biomarker of Fetal Brain Lesions
Status: RECRUITING
Conditions: Fetal Alcohol Syndrome
Interventions: BEHAVIORAL: ASQ parental questionnaire|BEHAVIORAL: Development scales|BEHAVIORAL: Scale of Conners|BEHAVIORAL: SCQ Questionnaire|PROCEDURE: Blood sample (mother)|PROCEDURE: Cord blood sample|PROCEDURE: Placenta sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Electrical Nerve Stimulation to Control Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Device Implant with Active Treatment|DEVICE: Device Implant without Active Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Cromolyn Sodium for the Treatment of Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: oral cromolyn sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Surgical Intracerebral Hemorrhage Removal
Status: NOT_YET_RECRUITING
Conditions: Intracranial Hemorrhages
Interventions: DEVICE: Minimally invasive surgical (MIS) intracranial hemorrhage Evacuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Stimulation To Induce Mothers Study
Status: RECRUITING
Conditions: Oxytocin|Labor Pain|Induction of Labor Affected Fetus / Newborn|Physiologic Effects of Drugs
Interventions: DEVICE: Electric breast pump|DRUG: Exogenous oxytocin intravenous infusion without nipple stimulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of DC-CIK Immunotherapy in the Treatment of Solid Tumors
Status: UNKNOWN
Conditions: Liver Cancer|Kidney Cancer|Nasopharyngeal Cancer|Lung Cancer|Colorectal Cancer|Breast Cancer
Interventions: OTHER: CELL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test of Trans-cranial Magnetic Stimulation (TMS) Intervention on Unilateral Neglect
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: trans-cranial magnetic stimulation|OTHER: trans-cranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia
Status: COMPLETED
Conditions: Anesthesia; Reaction
Interventions: DRUG: Midazolam|DRUG: Midazolam+Fentanyl Combination|DRUG: Midazolam+Ketamine Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pazufloxacin Mesilate Ear Drops in Patients With Chronic Suppurative Otitis Media
Status: UNKNOWN
Conditions: Chronic Suppurative Otitis Media
Interventions: DRUG: Pazufloxacin Mesilate ear drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: JS001 in Combination With RC48-ADC in Treatment of HER2-Positive Advanced Malignant Solid Tumors
Status: RECRUITING
Conditions: HER2-Positive Solid Tumors
Interventions: BIOLOGICAL: RC48-ADC in combinaton with JS001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postprandial Glycaemia in a Healthy Population After Intake of Milk and Oat Based Products
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Bread reference|OTHER: Product 1: Milk|OTHER: Product 2: Full fat milk + oat|OTHER: Product 3: Skim milk + oat, high fibre|OTHER: Product 4: Skim milk + oat, low fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CD19 CAR-T Expressing IL7 and CCL19 Combined With PD1 mAb for Relapsed or Refractory Diffuse Large B Cell Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Diffuse Large B-cell Lymphoma
Interventions: BIOLOGICAL: CD19-7×19 CAR-T plus PD1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Sleep Deprivation and Caffeine in Medical Professionals
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep Deprivation|Performance
Interventions: DIETARY_SUPPLEMENT: Military Energy Gum|DIETARY_SUPPLEMENT: Placebo Gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Estrogen + Estradiol Receptor Alpha Modulator Therapy on Oxidative Stress in Post-menopausal Women With and Without Sleep Apnea
Status: UNKNOWN
Conditions: Sleep Apnea|Post Menopausal|Oxidative Stress
Interventions: DRUG: Duavive (0.45 estrogens mg and 20 mg bazedoxifene)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apply the PD Model of Peripheral Oxytocin Action to a Multimodal Stimulus
Status: NOT_YET_RECRUITING
Conditions: Pain, Chronic
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Rate of Embryo Euploidy in Progestin-primed Ovarian Stimulation Cycles
Status: UNKNOWN
Conditions: IVF|Infertility
Interventions: DRUG: Medroxyprogesterone Acetate|DRUG: Ganirelix Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HoloSIM: Mixed Reality Medical Student Training in Complex Crisis Scenarios
Status: UNKNOWN
Conditions: Simulation of Physical Illness|Educational Problems
Interventions: DEVICE: HoloSIM Software via Hololens 2|OTHER: Training by Mannequin Based Simulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD
Status: ACTIVE_NOT_RECRUITING
Conditions: PTSD|Overweight|Obesity
Interventions: BEHAVIORAL: MOVE!+UP|BEHAVIORAL: MOVE!
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vonoprazan Study of Investigating the Effect on Sleep Disturbance Associated With Reflux Esophagitis- Exploratory Evaluation
Status: COMPLETED
Conditions: Reflux Esophagitis
Interventions: DRUG: Vonoprazan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Method To Measure Protein Digestion & Absorption
Status: COMPLETED
Conditions: Chronic Heart Failure|Pulmonary Disorder, Chronic Obstructive
Interventions: OTHER: sip feeding with stable isotope infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Two Stretching Techniques on Healthy Volunteers With Shortened Hamstrings
Status: COMPLETED
Conditions: Muscle Tone Abnormalities
Interventions: PROCEDURE: Neuromuscular Electrical Elongation|PROCEDURE: Proprioceptive Neuromuscular Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Pan-FGFR (Fibroblast Growth Factor Receptor) Inhibitor (Rogaratinib)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Rogaratinib (BAY1163877) oral solution|DRUG: Rogaratinib (BAY1163877) oral tablet|DRUG: Rogaratinib (BAY1163877) 800 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Loteprednol Ointment Following Eyelid Surgery
Status: WITHDRAWN
Conditions: Post-operative Healing Following Blepharoplasty and Ptosis Repair
Interventions: DRUG: Loteprednol etabonate ophthalmic ointment|DRUG: Vehicle Ophthalmic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: DRUG: Daptomycin 4 mg/kg|DRUG: Comparator: vancomycin|DRUG: Daptomycin 6 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Exacerbations of Asthma With Oral Montelukast in Children
Status: RECRUITING
Conditions: Status Asthmaticus
Interventions: DRUG: Montelukast Oral Granules|DRUG: Albuterol|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRPMS to Improve Mobility and Depression in Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: TRPMS (Transcranial Rotating Permanent Magnet Stimulation)|OTHER: Aerobic Exercise Program|OTHER: Computerized CT (Cognitive Training)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Experienced Chinese Herbal Formulas on Different Types of Precocious Puberty
Status: COMPLETED
Conditions: Precocious Puberty
Interventions: DRUG: ziyinxiehuo Granules|DRUG: zishenqinggan Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot/Ph I Safety and Efficacy of ODSH in Protein Losing Enteropathy Secondary to Single Ventricle Palliative Surgery
Status: TERMINATED
Conditions: Protein Losing Enteropathy
Interventions: DRUG: ODSH at 0.125 mg/kg/h|DRUG: ODSH at 0.375 mg/kg/h|DRUG: ODSH at 0.250 mg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indocyanine Green to Visualize Critical View of Safety During Laparoscopic Cholecystectomy for Acute Cholecystitis
Status: UNKNOWN
Conditions: Acute Cholecystitis|Acute; Cholecystitis, Choledocholithiasis|Acute Cholecystitis With Obstruction
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Microencapsulated Sublingual Glycine (Bidicin) on Cognitive Performance in Healthy Men After an Acute Stressor
Status: COMPLETED
Conditions: Healthy|Stress, Psychological|Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Microencapsulated Sublingual Glycine (MSG)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases
Status: COMPLETED
Conditions: HER-2 Positive Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Vinorelbine|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adding Morphine to ESP Block in Management of Acute PMP
Status: NOT_YET_RECRUITING
Conditions: Acute Post-mastectomy Pain Treatment
Interventions: PROCEDURE: erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase III Study of Adjuvant Chemotherapy With or Without Chemo-radiotherapy in Patients With Local Advanced Gastric Cancer After D2 Resection.
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: RADIATION: Adjuvant Concurrent Chemo-radiotherapy|DRUG: Adjuvant chemotherapy for active comparator group|DRUG: Adjuvant chemotherapy for experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aribulin Combined With Carboplatin and Bevacizumab in the Treatment of Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Aribulin;carboplatin;bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.
Status: COMPLETED
Conditions: Mycobacterium Avium-intracellulare Infection|HIV Infections
Interventions: DRUG: Ciprofloxacin hydrochloride|DRUG: Ethambutol hydrochloride|DRUG: Amikacin sulfate|DRUG: Azithromycin|DRUG: Rifampin|DRUG: Clofazimine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Carboplatin in Treating Patients With Circulating Tumor Cells Positive Metastatic Breast Cancer
Status: RECRUITING
Conditions: Estrogen Receptor Negative|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Negative|Recurrent Breast Carcinoma|Stage IV Breast Cancer|Triple-Negative Breast Carcinoma
Interventions: DRUG: Carboplatin|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Doxazosin Gastrointestinal Therapeutic System on Ambulatory Blood Pressure and Cardiovascular Risk Factors in Uncontrolled Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Doxazosin gastrointestinal therapeutic system (GITS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Circulating Fubctional Mitochondrias in Vitiligo Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin and Connective Tissue Diseases
Interventions: OTHER: Non segmental vitiligo|OTHER: Health Volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Action of Intra-auricular Topical Lidocaine on Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DRUG: Lidocaine 10 MG/ML|DRUG: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC