pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rescue Pharmacotherapy for OSA
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Placebo|DRUG: Acetazolamide|DRUG: Trazodone|DRUG: Atomoxetine and eszopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alleviating Carbohydrate-Counting Burden in T1DM Using Artificial Pancreas and Empagliflozin
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DRUG: Empagliflozin 25mg|DEVICE: Single hormone artificial pancreas|BEHAVIORAL: Meal strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFIRINOX + 9-Ing-41 + Losartan In Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma|Pancreatic Adenocarcinoma Metastatic
Interventions: DRUG: FOLFIRNINOX|DRUG: Losartan|DRUG: 9-ING-41
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artemether-Lumefantrine (AL) + 0.25 mg/kg primaquine|DRUG: Artemether-Lumefantrine (AL) combination|DRUG: Artemether-Lumefantrine (AL) + 0.4 mg/kg primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Vitiligous Lesions Repigmentation After the Administration of Atorvastatin Calcium Salt and Simvastatin-acid Sodium Salt in Patients With Active Vitiligo
Status: COMPLETED
Conditions: Non-segmental Vitiligo
Interventions: DRUG: 1% simvastatin-acid sodium salt ointment|DRUG: 1% atorvastatin calcium salt ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMN-673 With Carboplatin and Paclitaxel in Patients With Advanced BRCA-mutated Solid Tumor or Triple Negative Metastatic Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Metastatic Breast Cancer|BRCA-mutated Solid Tumor
Interventions: DRUG: BMN-673|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Proteinuria and Renal Function in Non-diabetic Patients With Progressive Renal Disease
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Progressive Muscle Relaxation and Mindfulness Meditation in Patients With Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: COPD|Mediation|Fatigue|Symptoms and Signs
Interventions: BEHAVIORAL: mindfullness and relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part II
Status: NOT_YET_RECRUITING
Conditions: Endothelial Dysfunction|Hemolysis|Fluid Overload
Interventions: DRUG: Treatment: additional albumin during cardiopulmonary bypass|DRUG: control: additional ringers during cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beneficial and Harmful Effects of Azathioprine and Allopurinol Versus Standard Azathioprine Therapy for Patients With Ulcerative Colitis
Status: UNKNOWN
Conditions: Colitis, Ulcerative|Colitis Ulcerative Exacerbation
Interventions: DRUG: Azathioprine and Allopurinol|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation
Status: UNKNOWN
Conditions: Emphysema or COPD|Aneurysm|Cystic Fibrosis|Alpha 1-Antitrypsin Deficiency
Interventions: DIAGNOSTIC_TEST: Venipuncture
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Manufacturing Lot of StaphVAX
Status: COMPLETED
Conditions: Staphylococcal Infections|Chronic Kidney Failure
Interventions: BIOLOGICAL: S. aureus Type 5 & 8 Capsular Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Aromatherapy in Hypertensive Individuals
Status: UNKNOWN
Conditions: Essential Hypertension|Aromatherapy|Stress, Physiological
Interventions: OTHER: Aromatherapy-inhalation method|OTHER: Aromatherapy-foot massage group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Caldolor (IV Ibuprofen) in Hospitalized Adult Orthopedic Patients
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Caldolor|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticoid Therapy in Acute Myocarditis
Status: NOT_YET_RECRUITING
Conditions: Acute Myocarditis
Interventions: DRUG: Intravenous administration of Methylprednisolone|DRUG: Oral Prednisone|DRUG: Perfusion of placebo|DRUG: Oral Prednisone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Patients Suffering From Heartburn and Backward Flow of Stomach Liquid Into the Esophagus
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DRUG: STW5 (Iberogast®, BAY98-7411)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double the Dose of Clopidogrel or Switch to Prasugrel to Antagonize Proton Pump Inhibitor Interaction.
Status: COMPLETED
Conditions: Anti Platelet Effects
Interventions: DRUG: Clopidogrel|DRUG: Prasugrel|DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Perimyocarditis After Covid-19 Vaccine
Status: UNKNOWN
Conditions: Perimyocarditis|Covid19
Interventions: DIAGNOSTIC_TEST: Laboratory Blood Tests|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: PCR|DIAGNOSTIC_TEST: Antibody test|DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Inflammation of the Anterior Segment by Laser Flashmeter in Patients Having Undergone Surgery of the Posterior Segment (Vitrectomy or Preindentation) During the First Postoperative Year. (FLAVIC)
Status: UNKNOWN
Conditions: Inflammation Eye
Interventions: OTHER: Laser Flare Meter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Peri Implant Bone Loss of Immediately Versus Conventionally Loaded Implants With a Single Prosthesis
Status: COMPLETED
Conditions: Periodontal Bone Loss
Interventions: PROCEDURE: immediate implant surgery|DEVICE: implant surgery (Straumann®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia
Status: COMPLETED
Conditions: Cognitive Deficits in Schizophrenia
Interventions: DRUG: ABT-288 Low Dose|DRUG: Placebo|DRUG: ABT-288 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eye Drops Study for Myopia Control in Schoolchildren
Status: UNKNOWN
Conditions: Myopia, Progressive|Atropine Allergy
Interventions: DRUG: eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biospecimen and Medical Data Collection and Tumor Biopsy in Creating Research Tissue Registry in Patients With Inflammatory or Invasive Breast Cancer
Status: RECRUITING
Conditions: Inflammatory Breast Carcinoma|Invasive Breast Carcinoma|Second Primary Malignant Neoplasm
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Interview|OTHER: Medical Chart Review|OTHER: Questionnaire Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Breeze3:Study of Gabapentin Extended Release in the Treatment of Vasomotor Symptoms(Hot Flashes)in Postmenopausal Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Gabapentin Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
Status: COMPLETED
Conditions: Quality of Recovery|Same Day Surgery|Nausea and Vomiting, Postoperative|Vaginal Prolapse
Interventions: DRUG: Dexamethasone|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Physical Activity Program to Reduce Long-term Cancer-related Fatigue in Metastatic Testicular Germ Cell Tumor Patients
Status: NOT_YET_RECRUITING
Conditions: Metastatic Testicular Cancer
Interventions: BEHAVIORAL: Physical activity recommendations|BEHAVIORAL: Connected activity tracker|BEHAVIORAL: Physical Activity (PA) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Interactions of Bisoprolol and Rosuvastatin
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Concor 5mg(Bisoprolol hemifumarate 5mg) 2Tab|DRUG: Crestor 20mg(Rosuvastatin calcium 20.80mg) 1Tab|DRUG: Concor 5mg 2T and Crestor 20 mg 1Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcutaneous Electrical Acupoint Stimulation for Opioid Consumption After Gastrointestinal Laparoscopic Surgery
Status: RECRUITING
Conditions: Transcutaneous Electrical Acupoint Stimulation
Interventions: OTHER: transcutaneous electrical acupoint stimulation|OTHER: transcutaneous electrical acupoint stimulation sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ponsegromab in People With Heart Failure
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Main cohort: Ponsegromab low dose|DRUG: Main cohort: Ponsegromab medium dose|DRUG: Main cohort: ponsegromab high dose|OTHER: Main cohort: Matched placebo|DRUG: Open-label, PK Cohort: ponsegromab low dose|DRUG: Open-label, PK Cohort: ponsegromab medium dose|DRUG: Open-label, PK Cohort: ponsegromab high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rituximab, Fludarabine, Cyclophosphamide, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed B-Cell Non-Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|RADIATION: yttrium Y 90 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Hematopoietic Cells in Children With Severe Combined Immunodeficiency Syndrome
Status: COMPLETED
Conditions: Severe Combined Immunodeficiency
Interventions: PROCEDURE: Stem cell transplant|DRUG: Filgrastim, Alemtuzumab|DEVICE: Miltenyi CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent-focused Intervention to Reduce HIV Risk in Gay and Bisexual Adolescents
Status: RECRUITING
Conditions: Hiv|Sexual Health
Interventions: BEHAVIORAL: Parents and Adolescents Talking about Healthy Sexuality (PATHS)|BEHAVIORAL: Lead with Love (LWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Muscle MRI in Charcot Mary Tooth Disease: a Prospective Cohort Study
Status: UNKNOWN
Conditions: Charcot-Marie-Tooth Disease, Type IA|Charcot-Marie-Tooth Disease Type 2A|Charcot-Marie-Tooth Disease, Type IB|Charcot-Marie-Tooth Disease, Type X
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Estimate The Time Course Of PF-00241939 Concentration In The Blood After Dosing With Oral Inhalation From Dry Powder Inhalers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F|DRUG: Treatment G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supervised Physical Activity in Young Women With Early Breast Cancer During Neoadjuvant Chemotherpy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: High Intensity Interval Training (HIIT)|DRUG: neoadjuvant treatment (doxorubicin, cyclophosphamide, paclitaxel, trastuzumab, pertuzumab)|OTHER: Standard Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Repeated Mesenchymal Stem Cells (MSC) in Patients With Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Mesenchymal Stem Cells (MSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: DRUG: APL-2|DRUG: APL-2|OTHER: Sham Procedure|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of Niacinamide 4% and Virgin Coconut Oil 30% for Secondary Prevention of Occupational Hand Dermatitis
Status: COMPLETED
Conditions: Contact Dermatitis of Hands
Interventions: OTHER: Niacinamide 4%|OTHER: Virgin Coconut oil 30%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies
Status: RECRUITING
Conditions: Advanced Unresectable Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: TAB004|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Intra-Articular Micro-Fragmented Adipose Transfer for the Treatment of Thumb Carpometacarpal Joint Arthritis
Status: WITHDRAWN
Conditions: Arthritis
Interventions: BIOLOGICAL: Micro-Fragmented Adipose Tissue (MFAT)|DRUG: Triamcinolone Acetonide 10mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil)
Status: RECRUITING
Conditions: Hepatitis C
Interventions: DRUG: Specialist - Epclusa 400Mg-100Mg Tablet|DRUG: Non- specialist - Epclusa 400Mg-100Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Neurodynamics on Lower Extremity Spasticity - a Study in Chronic Stroke
Status: COMPLETED
Conditions: Chronic Stroke|Stroke|Spasticity Post Stroke
Interventions: PROCEDURE: Tibial Nerve Neurodynamics|PROCEDURE: Lying in supine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pre-op NRT on Peri-operative Complications and Long-term Abstinence: A Pilot Trial in Patients Undergoing CABG Surgery
Status: TERMINATED
Conditions: Smoking Cessation
Interventions: DRUG: Nicoderm Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial
Status: COMPLETED
Conditions: Labor, Induced|Cervical Ripening
Interventions: COMBINATION_PRODUCT: Cervical Foley combined with Misoprostol|DRUG: Dinoprostone 10mg insert OR|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cisplatin With Alimta or Gemcitabine in Long Infusion for Mesothelioma
Status: UNKNOWN
Conditions: Mesothelioma
Interventions: PROCEDURE: Gemcitabine in long infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes
Status: RECRUITING
Conditions: Concussion, Mild|Vestibular Impairment|Cognitive Impairment
Interventions: OTHER: find association between vestibular impairment , cognitive fiunction with concussin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tamoxifen Citrate or Letrozole With or Without Bevacizumab in Treating Women With Stage IIIB or Stage IV Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Breast Carcinoma|Recurrent Breast Carcinoma|Stage III Breast Cancer AJCC v6|Stage IV Breast Cancer AJCC v6 and v7
Interventions: BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|OTHER: Questionnaire Administration|DRUG: Tamoxifen Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison for Oral Negative Pressure Therapy and CPAP for OSA Under Sleep Endoscopy Assistance: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: OSA|iNAP|DISE
Interventions: DEVICE: iNAP|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab and Pembrolizumab vs Pembrolizumab Monotherapy in PD-L1 Positive Head and Neck Squamous-Cell Carcinoma
Status: RECRUITING
Conditions: Recurrent Head and Neck Cancer|Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Head and Neck Carcinoma|Metastatic Head-and-neck Squamous-cell Carcinoma|Metastatic Head and Neck Cancer|HNSCC
Interventions: DRUG: Ramucirumab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Oxycodone Hydrochloride 50mg/mL Administered as an Infusion
Status: TERMINATED
Conditions: Severe Caner Pain
Interventions: DRUG: Oxycodone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massage Therapy in Reducing Chemotherapy-Induced Peripheral Neuropathy in Patients With Gastrointestinal or Breast Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Breast Neoplasm|Malignant Digestive System Neoplasm|Peripheral Neuropathy
Interventions: PROCEDURE: Massage Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels and Drug Effects of Single and Multiple Doses of BMS-986209 in Healthy Participants
Status: COMPLETED
Conditions: Health Participants
Interventions: DRUG: BMS-986209|OTHER: BMS-986209 Placebo|DRUG: Itraconazole|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Impact of Sodium Hypochlorite on the Physical Properties of Protaper Gold and Dia-X ProTaper.
Status: COMPLETED
Conditions: Dental Pulp Diseases
Interventions: DIAGNOSTIC_TEST: Finishing files of ProTaper Gold (F2) without effect to NaOCL|DIAGNOSTIC_TEST: Finishing files of ProTaper Gold (F2) with effect to NaOCL|DIAGNOSTIC_TEST: Finishing files of Dia-X ProTaper (D4) without effect to NaOCL|DIAGNOSTIC_TEST: Finishing files of Dia-X ProTaper (D4) with effect to NaOCL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-diabetic Effect of Gynostemma Pentaphyllum Tea in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Gynostemma pentaphyllum tea|DIETARY_SUPPLEMENT: Placebo tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tigecycline for Treatment of Rapidly Growing Mycobacteria
Status: COMPLETED
Conditions: Mycobacterium Abscessus Lung Disease|Rapidly Growing Mycobacterial Lung Disease
Interventions: DRUG: Tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy for Oral Mucositis Prevention of MIT-001 in Auto HSCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Mucositis|Lymphoma|Multiple Myeloma|Hematologic Cancer
Interventions: DRUG: MIT-001|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: G-CSF|DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: vincristine sulfate|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Selexipag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Glucagon in the Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-glucose Co-transporter-2 Inhibitors
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: LY2403021|DRUG: LY2403021 placebo|PROCEDURE: Standardised liquid meal|DRUG: Linagliptin|DRUG: Linagliptin placebo|DRUG: Empagliflozin|DRUG: Empagliflozin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Safety and Immunogenicity of a SARS-CoV-2(Severe Acute Respiratory Syndrome Coronavirus 2) Booster Vaccine (LEM-mR203)
Status: RECRUITING
Conditions: COVID-19 Infection|COVID-19 Vaccine Adverse Reaction
Interventions: BIOLOGICAL: LEM-mR203|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee
Status: COMPLETED
Conditions: Articular Cartilage Lesion of the Femoral Condyle
Interventions: DRUG: ChondroCelect implantation|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies
Status: UNKNOWN
Conditions: Physiological Effects of Drugs
Interventions: DRUG: Dexmedetomidine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases
Status: TERMINATED
Conditions: Colorectal Cancer Metastatic|Liver Metastases|KRAS Wild Type Colorectal Cancer
Interventions: DRUG: FOLFOX6|BIOLOGICAL: Bevacizumab|BIOLOGICAL: Panitumumab|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Class III Elastics on Stability of Orthopaedic Class III Correction
Status: ENROLLING_BY_INVITATION
Conditions: Class III Malocclusion|Underbite
Interventions: OTHER: Upper-lower clear plastic retainers + Class III elastics|OTHER: Upper-lower clear plastic retainers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving HIV Diagnosis, Linkage to Care, and Prevention Services With HIV Point-of-Care Nucleic Acid Tests
Status: RECRUITING
Conditions: HIV Infections
Interventions: DIAGNOSTIC_TEST: POC NAT & Adherence Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Deep Transcranial Magnetic Stimulation (TMS)- Treatment for Post Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Deep repetitive Transcranial Magnetic Stimulation (rTMS) real or sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Use of an Optical Coherence Tomography (OCT) Imaging System to Guide Additional Margin Cavity Shaves in Breast Conserving Surgery (BCS)
Status: TERMINATED
Conditions: Breast Cancer Female
Interventions: DEVICE: OCT- based investigational imaging device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: RFA (Radiofrequency Ablation) Versus EA (Ethanol Ablation) for Predominantly Cystic Thyroid Nodules
Status: UNKNOWN
Conditions: Thyroid Nodule
Interventions: PROCEDURE: radiofrequency ablation|PROCEDURE: Ethanol ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Lambda-1a for the Prevention and Treatment of SARS-CoV-2 (COVID-19) Infection
Status: TERMINATED
Conditions: Sars-CoV-2 Infection
Interventions: DRUG: Peginterferon lambda alfa-1a subcutaneous injection|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Predictors of Child Abuse Among School Going Children and the Impact of Structural Training on Child Abuse Among School Teachers
Status: NOT_YET_RECRUITING
Conditions: Child Abuse
Interventions: PROCEDURE: Impact of structural training on child abuse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Role of Induction Chemotherapy for High-risk Locally Advanced Nasopharyngeal Carcinoma in the Era of IMRT
Status: COMPLETED
Conditions: Nasopharyngeal Neoplasms
Interventions: DRUG: Cisplatin|DRUG: Paclitaxel|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Sancuso and IV Granisetron in Patients Aged 13 to 17 Years
Status: COMPLETED
Conditions: Chemotherapy Induced Nausea and Vomiting
Interventions: DRUG: granisetron transdermal system|DRUG: Granisetron IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery
Status: RECRUITING
Conditions: Bariatric Surgery
Interventions: DEVICE: Warm humidified CO2|DEVICE: Dry CO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of GNbAC1 in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: GNbAC1|BIOLOGICAL: GNbAC1 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combivent® Aerosol and Spacer, in Adult Patients With Moderate to Severe Asthma Crisis
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: salbutamol sulfate + ipratropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rule Out Transcatheter Aortic Valve Thrombosis With Post Implantation Computed Tomography (RETORIC)
Status: UNKNOWN
Conditions: Prosthetic Cardiac Valve Thrombosis|Cerebrovascular Accident|Prosthetic Valve Malfunction
Interventions: DRUG: Acenocoumarol|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2a Study Evaluating BIVV020 in Adults With Persistent/Chronic Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Immune Thrombocytopenia (ITP)
Interventions: DRUG: SAR445088 (BIVV020)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdiaphragmatic Pressure and Neural Respiratory Drive Measured During Inspiratory Muscle Training in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Threshold IMT®|DEVICE: PFLEX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Serous Carcinoma and Adjuvant Combined Intraperitoneal Chemotherapy and Radiation
Status: WITHDRAWN
Conditions: Uterine Carcinoma
Interventions: DRUG: Paclitaxel/Carboplatin|RADIATION: Pelvic radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Video-based Yoga Practices for Sedentary Women in Pandemic Days
Status: COMPLETED
Conditions: Women
Interventions: BEHAVIORAL: Sociodemographic profile, quality of life, sleep, fatigue, physical function and balance assessments|OTHER: Video-based yoga|OTHER: Face-to-face yoga|OTHER: physical exercise
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality of Life and Pain Outcomes Following Video-Assisted Thoracic Surgery (VATS) Anatomic Lung Resection Versus Thoracotomy and Anatomic Lung Resection
Status: COMPLETED
Conditions: Lung Cancer|Quality of Life|Video-assisted Thoracic Surgery (VATS)|Thoracotomy
Interventions: BEHAVIORAL: questionnaires|BEHAVIORAL: questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy
Status: NOT_YET_RECRUITING
Conditions: Abdominal Sepsis|Acute Respiratory Failure|Ventilation Therapy; Complications|Emergencies
Interventions: DIAGNOSTIC_TEST: Arterial blood gas analysis|DIAGNOSTIC_TEST: Venous blood gas analysis|DIAGNOSTIC_TEST: Esophageal pressure monitoring|DIAGNOSTIC_TEST: Intrabdominal pressure|DIAGNOSTIC_TEST: Electrical impedance tomopgraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Insulin Detemir in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Symtuza® (TAF/FTC/DRV/c)|DRUG: ABC/3TC/DTG + Symtuza® (TAF/FTC/DRV/c)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NICU Antibiotics and Outcomes (NANO) Follow-up Study
Status: NOT_YET_RECRUITING
Conditions: Premature Birth|Antibiotics|Neurodevelopment
Interventions: DRUG: Ampicillin|DRUG: Gentamicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synovial Tissue and Fat Pad Stromal Vascular Fraction Bioengineering in Patients With Knee Articular Cartilage Injury
Status: NOT_YET_RECRUITING
Conditions: Cell- and Tissue-Based Therapy|Cartilage Injury|Knee Injuries
Interventions: BIOLOGICAL: Synovial Tissue and Fat Pad Stromal Vascular Fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab (Avastin) in Unresectable/Recurrent Hemangioblastoma From Von-Hippel-Lindau Disease
Status: TERMINATED
Conditions: Hemangioblastomas|Von Hippel Lindau Disease
Interventions: DRUG: Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137)
Status: COMPLETED
Conditions: Carcinoma of the Head and Neck
Interventions: DRUG: Talimogene Laherparepvec|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Photobiomodulation Treatment for Diabetic Macular Oedema
Status: COMPLETED
Conditions: Diabetic Macular Oedema
Interventions: DEVICE: Ellex Integre NIR laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Wellroot PT Versus MTA in Pulpotomy of Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Pulpotomy
Interventions: OTHER: Premixed bioceramic paste wellroot PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis
Status: RECRUITING
Conditions: Peri-implant Mucositis
Interventions: PROCEDURE: Non-surgical treatment|PROCEDURE: Free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1922GCCC: Pembro and Bavituximab for Squamous Cell Carcinoma of Head and Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Bavituximab|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Japan Phase 2 Study of Niraparib in Participants With Advanced, Relapsed Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Immunization of COVID-19 Inactivated Vaccine With QIV and PPV23
Status: UNKNOWN
Conditions: Safety|Immunogenicity, Vaccine|COVID-19 Vaccines|Influenza Vaccines|Pneumococcal Vaccines
Interventions: BIOLOGICAL: Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: DRUG: metoprolol succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: P-Co-Li (Pulmonary Covid-19 Study)
Status: WITHDRAWN
Conditions: Covid19|Lung Inflammation|Hypoxemic Respiratory Failure
Interventions: OTHER: Steroid Taper (Prednisone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: lead-in FOLICOLOR Trial: Following Therapy Response Through Liquid Biopsy in Metastatic Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: PROCEDURE: Liquid biopsy sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SARC029: Trametinib and Pazopanib in Patients With GIST (Gastrointestinal Stromal Tumor)
Status: WITHDRAWN
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Pazopanib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of the EPITOPE Study to Evaluate Long-term Efficacy and Safety of DBV712 in Young Children
Status: ENROLLING_BY_INVITATION
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: DBV712 250 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Rosuvastatin Therapy on Cerebral Hemodynamics in Patients With Atherosclerotic Intracranial Arterial Stenosis
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Tirofiban on No-Reflow Phenomena
Status: COMPLETED
Conditions: No-Reflow Phenomenon
Interventions: DRUG: Tirofiban|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: NXL104|DRUG: Ceftaroline|DRUG: Placebo Infusion|DRUG: Ceftazidime|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Efficacy Study of Action Observation Therapy and Mirror Therapy After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Action observation therapy|BEHAVIORAL: Mirror therapy|BEHAVIORAL: Customary bilateral UE training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bimanual Robotic Exoskeletal Platform for the Treatment of the Upper Limb in Patients With Stroke. A Feasibility Study
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and bimanual serious games|DEVICE: Robotic rehabilitation using the Arm Light Exoskeleton Rehab Station (ALEx RS) and unimanual serious games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Lisinopril and Hydrochlorothiazide Tablets (20+25) mg Under Fasting Conditions
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Lisinopril and Hydrochlorothiazide Tablets (20+25) mg|DRUG: Zestoretic® 20/25 lisinopril/hydrochlorothiazide Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiological Epidemiology in Patients Experiencing Microbiological or Clinical Failure Following Reimplantation After a 2-stage Exchange Strategy for Hip or Knee Prosthetic Joint Infection
Status: COMPLETED
Conditions: Bone and Joint Infection|Bacterial Infections|EPIDEMIOLOGY
Interventions: OTHER: failure after reimplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Transcranial Magnetic Stimulation on Object Recognition
Status: COMPLETED
Conditions: Repetitive TMS (rTMS)|Sham rTMS|Bilateral rTMS|Unilateral rTMS
Interventions: PROCEDURE: Sham rTMS|PROCEDURE: Bilateral rTMS at same frequency and in phase|PROCEDURE: Bilateral rTMS at different frequencies|PROCEDURE: Bilateral rTMSat same frequency and out of phase|PROCEDURE: rTMS over TP8|PROCEDURE: rTMS over TP7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Geriatric Co-Management With Geriatric Guided Supportive Care in Older Patients Receiving Chemoradiation Therapy for Their Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: OTHER: geriatric co-management|OTHER: geriatric guided supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Antidepressants on Back Pain
Status: COMPLETED
Conditions: Back Pain|Sciatica
Interventions: DRUG: Desipramine|DRUG: Fluoxetine|DRUG: Benztropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Frozen Shoulder Treatment Using 432 Hertz Frequency Music: A Clinical Trial
Status: COMPLETED
Conditions: Frozen Shoulder|432 Hertz Frequency Music|Manual Therapy|Exercise
Interventions: OTHER: 432 Hertz frequency music|OTHER: TENS|OTHER: Mobilization|OTHER: Exercises|OTHER: Hotpack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical and Cognitive Training in Neuroplasticity, Health and Cognition. Movement Project
Status: COMPLETED
Conditions: Aging|Cognitive Function 1, Social
Interventions: BEHAVIORAL: Physical exercise|BEHAVIORAL: Cognitive training|BEHAVIORAL: Combined training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: transcatheter arterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DRUG: cefuroxime|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION