pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)
Status: RECRUITING
Conditions: HER2 Positive Metastatic Breast Cancer
Interventions: DRUG: ARX788
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ05105 Tablets in Subjects With Glucocorticoid-Refractory Acute Graft-Versus-Host Disease (aGVHD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Glucocorticoid-Refractory aGVHD
Interventions: DRUG: TQ05105 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Infrapatellar Strap Treatment on Pain Extent and Athletic Measures in Young Athletes
Status: COMPLETED
Conditions: Patellar Tendonitis|Jumper's Knee|Patellar Tendinopathy
Interventions: DEVICE: patella knee strap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of Phase Lag Entropy(PLE) as an Indicator of Depth of Sedation in Patients Undergoing Spinal Anesthesia
Status: UNKNOWN
Conditions: Surgery Requiring Spinal Anesthesia
Interventions: DEVICE: apply phase lag entropy sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and Symptoms
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: carboxymethylcellulose 0.5% +glycerin 0.9%|DRUG: sodium hyaluronate 0.18%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Immunogenicity of AVT02 With Moderate-to-Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remember Stuff: A Dyadic-focused Technology to Support Persons With Alzheimer's Disease in the Community
Status: COMPLETED
Conditions: Anxiety|Depression|Caregiver Burnout|Anxiety Generalized
Interventions: OTHER: Remember Stuff: A Dyadic-focused Technology to Support Persons with Alzheimer's Disease in the Community
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient|Hematopoietic and Lymphoid Cell Neoplasm
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Etoposide|RADIATION: Fractionated Stereotactic Radiation Therapy|DRUG: Goat Milk|BIOLOGICAL: Palifermin|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OCP Pretreatment in PCOS Patients Undergoing ICSI Using Antagonist Protocol
Status: UNKNOWN
Conditions: Subfertility, Female
Interventions: DRUG: 0.075mg gestodene/0.03mg ethinylestradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioequivalency of Comparing Single 100 mg Doses Of Cord's 50 mg Desipramine HCL Tablets To Merrell Dow's 50 mg Norpramin Tablets
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Desipramine HCl 50 mg Tablets Cord Laboratories|DRUG: Norpramin 50 mg Tablets Merrell Dow Pharmaceuticals, Inc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Community-Based Kiosks for Hearing Screening and Education
Status: COMPLETED
Conditions: Hearing Loss
Interventions: PROCEDURE: Automated hearing test|PROCEDURE: Pure-tone Screener test|PROCEDURE: Digits-in-noise test|PROCEDURE: No screening test|PROCEDURE: Automated hearing test/Motivation video|PROCEDURE: Pure-tone Screener/Motivation video|PROCEDURE: Digits-in-noise test/Motivational video|PROCEDURE: No screening test/Motivational video|PROCEDURE: Home Hearing Screening Test|PROCEDURE: Home Hearing Screening Test/Brief video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: HOPE With Cytokine Filtration in Liver Transplantation (Cyto-HOPE)
Status: RECRUITING
Conditions: Liver Transplantation|Post-Reperfusion Syndrome|Ischaemia-Reperfusion Injury|Early Allograft Dysfunction
Interventions: PROCEDURE: HOPE with cytokine filtration by CytoSorb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurment of Interleuukin-6 at Exhaled Breath Condensate of Covid-19 Patients and Post Covid-19 Patients With Lung Fibrosis Randomized Controlled Study
Status: UNKNOWN
Conditions: Inflammatory Response|Immunological Abnormality|COVID-19
Interventions: PROCEDURE: measurment of interleukin-6 at exhaled condensate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Examine the Lung When People With Diabetes Take an Inhaled Form of Insulin, Compared to Subcutaneous Insulin.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Inhaled insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theoretical Compared With hands-on Training of Vaginal Breech Management
Status: COMPLETED
Conditions: Vaginal Abnormality - Baby Delivered
Interventions: OTHER: hands-on training|OTHER: frontal teaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Muscle Preservation Hamstring Graft for ACL Reconstruction
Status: UNKNOWN
Conditions: Graft Healing
Interventions: PROCEDURE: Muscle preservation|PROCEDURE: No muscle preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Integrated Traditional Chinese and Western Medicine Treat Early Stage DKD
Status: COMPLETED
Conditions: Diabetic Nephropathy Type 2
Interventions: DRUG: HuangQi Decoction|DRUG: HuangQi Decoction placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endovenous Ablation Combined With Fat Grafting for Venous Ulcers
Status: UNKNOWN
Conditions: Varicose Ulcer
Interventions: PROCEDURE: Fat grafting|PROCEDURE: Endovenous ablation of superficial venous reflux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Live Biotherapeutic Product MRx0518 With Hypofractionated Radiation Therapy in Resectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: MRx0518|RADIATION: Hypofractionated Preoperative Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Norovirus Bivalent Virus-Like Particle Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Norovirus Prevention
Interventions: BIOLOGICAL: Norovirus Bivalent VLP Vaccine|DRUG: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Implementing TMC-CP01 Treatment Based on the Virtual Autonomic Neuromodulation Induced Systemic Healing System in Reducing Pain and Opioid Requirement in Subjects Suffering From Chronic Low Back Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Low-back Pain
Interventions: DEVICE: Flowly (TMC-CP01)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptives in the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X|Insulin Resistance|Obesity|Cardiovascular Diseases
Interventions: DRUG: Ortho Tri Cyclen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial of AZD2014 in RICTOR Amplified Solid Cancer Patients Refractory to Standard Chemotherapy
Status: WITHDRAWN
Conditions: Solid Tumor
Interventions: DRUG: Vistusertib(AZD2014)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Different Types of Physical Therapy for Treating People With a Meniscal Tear and Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Meniscal Degeneration|Osteoarthritis, Knee
Interventions: BEHAVIORAL: TeMPO Home Exercise Program|BEHAVIORAL: Motivational SMS Messages|BEHAVIORAL: In-Clinic Topical Therapy|BEHAVIORAL: In-Clinic Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Post-radiation Xerostomia With Allogeneic Mesenchymal Stromal Stem Cells
Status: NOT_YET_RECRUITING
Conditions: Xerostomia Following Radiotherapy
Interventions: BIOLOGICAL: allogeneic mesenchymal stromal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of a Detection and Prevention Program for Frail Community-dwelling Older Adults
Status: COMPLETED
Conditions: Older Adults
Interventions: BEHAVIORAL: Tailored care and support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial in knEe Osteoarthritis Using Low Intensity Ultrasound - Evaluating Feasibility (RELIEF)
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: low intensity, pulsed ultrasound|DEVICE: sham ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)
Status: COMPLETED
Conditions: Eosinophilic Gastritis|Eosinophilic Duodenitis
Interventions: DRUG: lirentelimab (AK002)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RAPID: Reducing Pain; Preventing Depression
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Physical Therapy for knee OA|BEHAVIORAL: Cognitive Behavioral Therapy for Pain CBT-P|OTHER: Enhanced Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Cleverscope. A New Medical Device for Tracheal Intubation
Status: UNKNOWN
Conditions: Anesthesia Intubation Complication|Difficult Intubation
Interventions: DEVICE: Cleverscope|DEVICE: Laryngoscope / Videolaryngoscope C-MAC® Storz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POC Strategies to Improve TB Care in Advanced HIV Disease
Status: COMPLETED
Conditions: Extrapulmonary Tuberculosis|Tuberculosis, Pulmonary|Human Immunodeficiency Virus (HIV)|Acquired Immunodeficiency Syndrome
Interventions: DIAGNOSTIC_TEST: LF-LAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Pharmacokinetics of Smoked Cannabis in Healthy Patients
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: PPP001|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of En Bloc Versus Non-En Bloc Esophagectomy in Esophageal Cancer
Status: TERMINATED
Conditions: Esophageal Neoplasms
Interventions: PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Evaluation of Acute Stroke for Using in Regenerative Cell Elements
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: BIOLOGICAL: HLCM051|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib-Dexamethasone-Doxorubicin-Study
Status: COMPLETED
Conditions: Multiple Myeloma|Renal Insuficiency
Interventions: DRUG: Dexamethasone, Bortezomib, Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 50 mL of sodium chloride (0,9%)|DRUG: Morphine 0,05mg/kg|DRUG: Naloxone 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Imagery Rescripting and Imaginal Exposure for Social Anxiety: Mechanisms and Outcomes in an Analog Sample
Status: RECRUITING
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Imaginal exposure one-session|BEHAVIORAL: Imagery rescriptinf one-session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Feeding Regimen on Recovery of Children Aged 6-59 Months With Moderate Acute Malnutrition in Bangladesh.
Status: NOT_YET_RECRUITING
Conditions: Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: Wheat Soy Blend Plus Plus (WSB++) with nutrition counselling|DIETARY_SUPPLEMENT: 15 Micro Nutrient Powder (15 MNP) with improved nutrition counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Upadacitinib in Pediatric Participants With Severe Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib (ABT-494)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Cardiac Dysfunction in Critical Illnes
Status: RECRUITING
Conditions: Multi Organ Failure|Left Ventricular Dysfunction|Right Ventricular Dysfunction|Tako Tsubo Cardiomyopathy|Myocardial Infarction|Cardiomyopathy, Stress
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Cardiac magnetic resonance imaging|DIAGNOSTIC_TEST: Coronary CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cetuximab, Cisplatin, and Irinotecan in Treating Patients With Metastatic Esophageal Cancer, Gastroesophageal Junction Cancer, or Gastric Cancer That Did Not Respond to Previous Irinotecan and Cisplatin
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin|DRUG: irinotecan hydrochloride|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Market Registry of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis Implanted in Peripheral Vessels
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Vascular Diseases
Interventions: DEVICE: GORE VIABAHN VBX Balloon Expandable Endoprosthesis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SyncAV Study: Investigation of the Efficacy of the SyncAV Fusion Pacing Algorithm on Exercise
Status: UNKNOWN
Conditions: Heart Failure, Systolic
Interventions: OTHER: SyncAV algorithm on|OTHER: SyncAV algorithm off
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antifugal Effect of Recombinant Human Granulocyte-macrophage Stimulating Factor (rhGM-CSF) in Patients Post Allo-HSCT
Status: COMPLETED
Conditions: Mycoses
Interventions: DRUG: rhGM-CSF group|DRUG: rhG-CSF+rhGM-CSF group|DRUG: rhG-CSF group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)
Status: SUSPENDED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|OTHER: PfSPZ Diluent|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Stargardt Disease 1
Interventions: DRUG: Tinlarebant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Human Milk in Young Children Receiving Bone Marrow Transplantation
Status: COMPLETED
Conditions: Bone Marrow Transplant - Autologous or Allogeneic
Interventions: DIETARY_SUPPLEMENT: Breastmilk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Molecular Markers in Cutaneous Inflammation Between Psoriatic Lesional Skin and Healthy Non-lesional Skin
Status: COMPLETED
Conditions: Psoriasis
Interventions: PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lipid Efficacy/Tolerability Study (0524A-020)
Status: COMPLETED
Conditions: Primary Hypercholesterolaemia|Mixed Hyperlipidaemia
Interventions: DRUG: niacin (+) laropiprant|DRUG: ER-niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus Clopidogrel
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elimination of Albumin-Bound Substances by MARS and Prometheus
Status: COMPLETED
Conditions: Liver Failure
Interventions: DEVICE: MARS (Molecular Adsorbents Recirculating System)|DEVICE: Prometheus (FPSA, Fractionated Plasma Separation and Adsorption)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Twice-Daily Insulin Lispro Low Mixture Compared to a Once-Daily Long Acting Insulin Comparator in Patients Who Have Been Using One or More Oral Antihyperglycemic Agents Without Insulin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Lispro low mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Cannabidiol for Tobacco Cessation
Status: RECRUITING
Conditions: Tobacco Use|Tobacco Smoking|Tobacco Dependence|Tobacco Use Disorder|Tobacco Use Cessation
Interventions: DRUG: 300 mg Cannabidiol|DRUG: 600 mg Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)
Status: COMPLETED
Conditions: FAP|Familial Amyloid Polyneuropathy|TTR|Transthyretin|Amyloidosis
Interventions: DRUG: Inotersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft Injuries of the Hand, Wrist and Fingers.
Status: COMPLETED
Conditions: Soft Tissue Injuries|Distal Radius Fracture|Metacarpal Fracture|Carpal Fracture|Carpal Tunnel Syndrome|Thumb Osteoarthritis|Dupuytren's Disease
Interventions: OTHER: Experimental: Tablet application|OTHER: Comparator: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nasal Spray Calcitonin on Recurrence of Aggressive Central Giant Cell Granuloma
Status: COMPLETED
Conditions: Central Giant Cell Granuloma
Interventions: DRUG: nasal spray calcitonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olaparib in Patients With Recurrent Ovarian Cancer Wild Type for Germline and Somatic BRCA 1 and 2 Genes: The MITO 31 Translational Study
Status: RECRUITING
Conditions: BRCA Wild Type Platinum Sensitive Recurrent Ovarian Cancer
Interventions: DRUG: Olaparib tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lopinavir/Ritonavir in PLWH With High-Grade AIN
Status: RECRUITING
Conditions: High-Grade Anal Intraepithelial Neoplasia
Interventions: DRUG: Lopinavir / Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sepsis Prognosis and Diagnosis in the Emergency Department (SPEED)
Status: WITHDRAWN
Conditions: Respiratory Tract Infections|Urinary Tract Infections|Intra-Abdominal Infections|Skin and Soft Tissue Infection|Suspected Meningitis/Encephalitis or Any Other Infection|Sepsis
Interventions: DIAGNOSTIC_TEST: IMX-BVN-4 and IMX-SEV-4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma|Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma|Low Grade Glioma|Malignant Glioma|Recurrent Childhood Central Nervous System Neoplasm|Recurrent Childhood Ependymoma|Recurrent Childhood Malignant Germ Cell Tumor|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Childhood Rhabdomyosarcoma|Recurrent Childhood Soft Tissue Sarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Glioma|Recurrent Hepatoblastoma|Recurrent Langerhans Cell Histiocytosis|Recurrent Malignant Solid Neoplasm|Recurrent Medulloblastoma|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Refractory Childhood Malignant Germ Cell Tumor|Refractory Ependymoma|Refractory Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Refractory Glioma|Refractory Hepatoblastoma|Refractory Langerhans Cell Histiocytosis|Refractory Malignant Glioma|Refractory Malignant Solid Neoplasm|Refractory Medulloblastoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Refractory Primary Central Nervous System Neoplasm|Refractory Rhabdomyosarcoma|Refractory Soft Tissue Sarcoma|Rhabdoid Tumor|Wilms Tumor
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodixanol in Multidetector-Row Computed Tomography-Coronary Angiography (MDCT-CA)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Iodixanol 320 mg I/Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar I Disorder|Depression, Anxiety|Stress
Interventions: DRUG: Magnesium vitamin B6|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome|Secondary Acute Myeloid Leukemia
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Basiliximab|DRUG: Fludarabine Phosphate|DRUG: Indium In 111-DOTA-Basiliximab|DRUG: Melphalan|BIOLOGICAL: Palifermin|RADIATION: Total Lymphoid Irradiation|RADIATION: Total Marrow Irradiation|BIOLOGICAL: Yttrium Y 90 Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4 x Epirubicin, Cyclophosphamide, Followed by 4 x Docetaxel Versus 6 x CMF / 6 x CEF
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|DRUG: Methotrexate|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy of LAI When Added to Multi-drug Regimen Compared to Multi-drug Regimen Alone
Status: COMPLETED
Conditions: Mycobacterium Infections, Nontuberculous
Interventions: DRUG: LAI (Liposomal Amikacin for Inhalation) 590 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pilot Study of the Percutaneous Ultrasound Jejunostomy Procedure
Status: NOT_YET_RECRUITING
Conditions: Jejunostomy; Complications|Enteral and Supplement Feeds Adverse Reaction|Safety Issues
Interventions: DEVICE: Percutaneous Ultrasound Jejunostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANCHORS Alcohol & Sexual Health Study: UH3 Project
Status: RECRUITING
Conditions: Alcohol Use, Unspecified|Substance Use|Sex Behavior
Interventions: DRUG: PrEP acronym (pre-exposure prophylaxis)|BEHAVIORAL: Initial Web Survey|BEHAVIORAL: Interactive Voice Response (IVR) monitoring|BEHAVIORAL: Educational material on alcohol and sexual health behavior|BEHAVIORAL: Interactive Voice Response (IVR) assessment with personalized information|BEHAVIORAL: Personalized information based on web-based survey responses & standardized information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Natural Killer (NK) Cell Infusion|BIOLOGICAL: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphoma
Status: COMPLETED
Conditions: Lymphoblastic Leukemia|Lymphoblastic Lymphoma
Interventions: DRUG: Everolimus|DRUG: Nelarabine|DRUG: Cyclophosphamide|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: JWCAR201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Carboplatin Followed By Docetaxel in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effects of Trimbow to Fostair in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Trimbow pMDI|DRUG: Fostair pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Anlotinib Combined With Penpulimab in Subjects With Gynecological Cancer
Status: RECRUITING
Conditions: Gynecological Cancer
Interventions: DRUG: Penpulimab|DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML
Status: NOT_YET_RECRUITING
Conditions: Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)|Myelodysplastic Syndrome (MDS)/AML|Chronic Myelomonocytic Leukemia (CMML)
Interventions: DRUG: S227928|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Rate Range Finding Study of Propofol for minimal-to Moderate Sedation on Upper & Lower Endoscopic Tests
Status: COMPLETED
Conditions: Gastrointestinal Endoscopy|Gastrointestinal Polypectomy
Interventions: DRUG: Placebo|DRUG: ICI35,868 (propofol)|DRUG: ICI35,868 (propofol)|DRUG: ICI35,868 (propofol)|DRUG: ICI35,868 (propofol)|DRUG: ICI35,868 (propofol)|DRUG: ICI35,868 (propofol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
Status: COMPLETED
Conditions: Atherosclerosis|Vascular Disease|Cognitive Decline|Hearing Loss|Inflammation|Age-Related Memory Disorder
Interventions: BEHAVIORAL: folic acid (0.8 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: RISE With Veteran Service Providers
Status: RECRUITING
Conditions: Domestic Violence|Veterans Family|Veterans|Child Maltreatment
Interventions: OTHER: Violence, Evidence, Guidance, Action Project (VEGA) Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of COVID-19 Convalescent Plasma (CCP) on Coronavirus-associated Complications in Hospitalized Patients
Status: COMPLETED
Conditions: COVID-19|Sars-CoV2
Interventions: BIOLOGICAL: COVID-19 Convalescent Plasma (CCP)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
Status: COMPLETED
Conditions: Muscle Tension Dysphonia|Vocal Fold Palsy|Vocal Cord Paralysis|Presbylarynx|Dysphonia
Interventions: DEVICE: Acapella Choice|DEVICE: Tube-in-water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Scapholunate Ligament Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Scapholunate Dissociation
Interventions: PROCEDURE: Arthroscopic Scapholunate Ligament Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Phase III Study, Multicenter，Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma.
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Tislelizumab, Cisplatin, Gemcitabine and Trilaciclib|DRUG: Tislelizumab, Cisplatin, Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H. Pylori Screen-and-treat Study in a Population of Young Adults
Status: RECRUITING
Conditions: Gastric Cancer|H Pylori Infection|H Pylori Eradication|H-pylori
Interventions: DRUG: Bismuth-based quadruple therapy|DRUG: Levofloxacin-based quadruple therapy|DRUG: Standard triple therapy|DRUG: Levofloxacin-based triple
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Racial Differences in Serum Sodium and Blood Pressure Regulation
Status: RECRUITING
Conditions: Sodium Excess|Racial Disparities|Blood Pressure|Cardiovascular Risk Factor
Interventions: OTHER: Acute Salt (sodium chloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body Weight
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Cagrilintide|DRUG: Semaglutide|DRUG: Atorvastatin|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EUS-CPN With and Without Bupivacaine
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS-CPN without bupivacaine|PROCEDURE: EUS-CPN with bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare Omeprazole Administered as Zegerid® Powder and as Prilosec® Capsule in Healthy Participants (P08050)(CL2010-12)
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: omeprazole/sodium bicarbonate|DRUG: omeprazole magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swallowing Disorders in Minimally Consciousness Patients (MCS)
Status: UNKNOWN
Conditions: Swallowing Disorder|Traumatic Brain Injury
Interventions: OTHER: videofluoroscopy|OTHER: Wessex Head Injury Matrix scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Extension Study of Lapatinib Plus Herceptin With or Without Endocrine Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Lapatinib|DRUG: Letrozole|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zoledronate and BMS-275291 in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: rebimastat|DRUG: zoledronic acid|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants
Status: COMPLETED
Conditions: Gram-negative Bacterial Infections
Interventions: DRUG: nacubactam|DRUG: meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CYBERnetic LowEr-Limb CoGnitive Ortho-prosthesis Plus Plus, 1st Clinical Study
Status: COMPLETED
Conditions: Transfemoral Amputation
Interventions: DEVICE: CLs++
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Oculomotor Training in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Oculomotor; Disorder
Interventions: OTHER: Control Group|OTHER: Oculomotor Training Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oral Preoperative Carbohydrate on Early Postoperative Outcome After Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: preoperative carbohydrate loading|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Transcutaneous Acupoint Electrical Stimulation on Intestinal Obstruction After Gastrointestinal Surgery
Status: COMPLETED
Conditions: Postoperative Intestinal Obstruction
Interventions: DEVICE: transcutaneous acupoint electrical stimulation|DEVICE: no transcutaneous acupoint electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Lipidil® Supra (Fenofibrate 160mg) Versus SYO-0805 (Fenofibrate 65mg)
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Sequence 1|DRUG: Sequence 2|DRUG: Seqeunce 3|DRUG: Sequence 4|DRUG: Sequence 5|DRUG: Sequence 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Tube Voltage Computed Tomographic (CT) Urography Using Low Concentration Iodine Contrast Agent
Status: UNKNOWN
Conditions: Exposure to Medical Diagnostic Radiation
Interventions: RADIATION: Computed tomographic urography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity
Status: UNKNOWN
Conditions: Tetraplegia|Plegia|Paresis|Cervical Spinal Cord Injury
Interventions: PROCEDURE: Nerve reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinic Modulation of the Default Network
Status: COMPLETED
Conditions: Magnetic Resonance Imaging|Cognition|Nicotine|Mecamylamine
Interventions: DRUG: Placebo|DRUG: Nicotine|DRUG: Mecamylamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Respiratory Motion-Corrected Cone-Beam CT in Radiation Treatment of Thoracic and Abdominal Cancers
Status: COMPLETED
Conditions: Gastric Cancer|Lung Cancer
Interventions: PROCEDURE: respiration correlated CT scan|PROCEDURE: respiration correlated CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Better Mechanistic Understanding of and Risk Stratification for Ventricular Tachyarrhythmias Through ECGI
Status: ENROLLING_BY_INVITATION
Conditions: Ventricular Tachycardia|Ventricular Arrythmia|Ventricular Fibrillation|Polymorphic Ventricular Tachycardia|Sudden Cardiac Death|Sudden Cardiac Arrest|Sudden Cardiac Death Due to Cardiac Arrhythmia|Heart Arrest|Cardiac Death|Cardiac Arrest|Cardiac Arrhythmia|Congenital Heart Disease
Interventions: DIAGNOSTIC_TEST: ECG-Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Computerized and Mailed Reminders in Increasing the Rate of Colorectal Cancer Screening in Adults With an Average Risk for Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: counseling intervention|PROCEDURE: fecal occult blood test|PROCEDURE: screening colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Low Dose Rivaroxaban in Patients With Anterior Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Patient With Anterior Myocardial Infarction
Interventions: DRUG: -group of patients(75 patients) will receive low dose rivaroxaban myocardial infarction plus (acetylsalicylic acid 75 mg and clopidogrel 75 mg|DRUG: (acetylsalicylic acid 75 mg once daily orally and clopidogrel 75 mg once daily orally only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Teriparatide for Improved Knee Prosthesis Fixation
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: teriparatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Local Application of Hyaluronic Acid (HYADENT BG) With Free Soft Tissue Grafing Improves Treatment Outcomes.
Status: COMPLETED
Conditions: Gingival Recession, Plastic Surgery
Interventions: DRUG: Hyaluronic Acid (HYADENT BG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy
Status: RECRUITING
Conditions: Colorectal Cancer|Colorectal Cancer Metastatic|MSI-H Colorectal Cancer|dMMR Colorectal Cancer|Cancer|Colon Adenocarcinoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inhibition of Ovulation, Patch, Ethinylestradiol and Gestodene
Status: TERMINATED
Conditions: Contraception|Ovulation Inhibition
Interventions: DRUG: Ethinylestradiol/Gestodene (BAY86-5016)|DRUG: Ethinylestradiol/Gestodene (BAY86-5016)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema
Status: COMPLETED
Conditions: Chronic Hand Dermatitis
Interventions: DRUG: ASN002|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Poziotinib|DRUG: Itraconazole|DRUG: Phenytoin|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DRUG: Ferumoxytol|DRUG: Iron Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defining the Role of the Skin Microbiome in Immune-related Adverse Events
Status: UNKNOWN
Conditions: Vitiligo|Skin Melanoma
Interventions: PROCEDURE: skin swabs at lesional and non-lesional sites|PROCEDURE: skin swabs on skin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Electrical Impedance Myography (EIM) in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Charcot-Marie-Tooth Disease|Multiple Sclerosis
Interventions: DEVICE: Electrical impedance myography (EIM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Ketoprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cranberry Powder Supplements on Gut Microbiota Diversity and Metabolic Syndrome
Status: COMPLETED
Conditions: Overweight|Insulin Resistance|Microbiota|Endotoxemia|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Cranberry powder|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION