pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multicenter Study of Intensive Concomitant Chemoradiotherapy With Filgrastim (GCSF) for Patients With Locoregionally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck
Interventions: DRUG: Hydroxyurea|DRUG: 5- Fluorouracil|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Dose Escalated Radiation for Painful Non-Spine Bone Metastases and Painful Non-Bone Metas
Status: RECRUITING
Conditions: Neoplasm Metastases|Metastases, Neoplasm
Interventions: BIOLOGICAL: EXTERNAL BEAM RADIATION
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Radiation Therapy in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Post-operative adjuvant therapy|DRUG: neoadjuvant therapy|PROCEDURE: therapeutic surgical procedure|RADIATION: Radiation therapy with concurrent Paclitaxel|DRUG: Hormonal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Malignant Neoplasm in the Liver|Resectable Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Diffusion Weighted Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
Status: COMPLETED
Conditions: Adult Intracranial Tumor|Adult Solid Tumor
Interventions: DRUG: Remifentanil|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies
Status: RECRUITING
Conditions: Feeding Tube|Children With Medical Complexity|Tracheostomy|Feeding Disorder, Infancy or Early Childhood
Interventions: OTHER: Tube weaning therapy intervention|OTHER: Feeding Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trimethoprim-Sulfamethoxazole or Doxycycline for Skin and Soft Tissue Infections
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: trimethoprim-sulfamethoxazole or doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 VaccinE Response in Rheumatology Patients
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Spondylarthritis
Interventions: DRUG: Upadacitinib|DRUG: Abatacept|DRUG: Secukinumab|DRUG: Tofacitinib|DRUG: TNF Inhibitor|DRUG: Canakinumab Injection|DRUG: Baricitinib|DRUG: Ixekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Phone Based Intervention to Protect Mental Health in Healthcare Workers at Frontline Against COVID19
Status: COMPLETED
Conditions: Mental Health Disorder|Depression|Posttraumatic Stress Disorder|Burnout|Anxiety Disorders
Interventions: BEHAVIORAL: Intervention App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Therapeutic Targets Tailored Ch and IMRT as Neoadjuvant Treatment in Rectal Carcinoma Patients
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Therapeutic target tailored chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Long-Term Safety, Tolerability, and Biological Activity of ATYR1940 in Participants With Limb Girdle and Facioscapulohumeral Muscular Dystrophy (FSHD)
Status: COMPLETED
Conditions: Facioscapulohumeral Muscular Dystrophy|Limb Girdle Muscular Dystrophy
Interventions: DRUG: ATYR1940
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Respiratory Symptoms of Pulmonary Irradiation in Interstitial Lung Disease
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Interstitial Lung Disease
Interventions: DIETARY_SUPPLEMENT: N-Acetyl cysteine|DRUG: Dexamethasone Oral|DIETARY_SUPPLEMENT: N-Acetyl cysteine Placebo|DRUG: Dexamethasone Placebo|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NeoAdjuvant Pembrolizumab and STEreotactic Radiotherapy Prior to Nephrectomy for Renal Cell Carcinoma
Status: RECRUITING
Conditions: Renal Cell Carcinoma, Clear Cell, Somatic
Interventions: DRUG: Pembrolizumab|RADIATION: Stereotactic Ablative Radiotherapy|PROCEDURE: Nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality for AnxIety Disorders - Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Social Anxiety|Social Phobia
Interventions: BEHAVIORAL: Cognitive behavioral therapy with exposure in virtual reality|BEHAVIORAL: Cognitive behavioral therapy with exposure in vivo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Disoproxil Fumarate (TDF) 300mg 3 Years RD Therapy Chinese Chronic Hepatitis B (CHN) CHB Multiple Nucleos(t)Ide Analogues (NAs) Failure Points Pts PH4 PMS Study
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fat Distribution in Healthy Early Postmenopausal Women
Status: COMPLETED
Conditions: Healthy|Postmenopause
Interventions: DRUG: Climodien / Lafamme (BAY86-5027)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)
Status: COMPLETED
Conditions: Coronary Arteriosclerosis
Interventions: DRUG: Rosuvastatin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SONOlysis in Risk REduction of Symptomatic and Silent Brain infarCtions dUring Cardiac surgEry
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft Redo|Heart Valve Diseases
Interventions: PROCEDURE: sonolysis|PROCEDURE: cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi Dimensional System for Evaluating a Preventive Program for Upper Extremity Disorders Among Computer Operators
Status: UNKNOWN
Conditions: Musculoskeletal Disorders|Upper Extremity Pain Chronic
Interventions: BEHAVIORAL: Ergonomic intervention|BEHAVIORAL: Standard ergonomic intervention|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bag-Valve-Guedel Adaptor vs Common Face Mask for the Ventilation of Anesthetized Bearded Men
Status: UNKNOWN
Conditions: Ventilation
Interventions: DEVICE: Begin with BVGA|DEVICE: Begin with Face-mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Oxaloacetate in Alzheimer's Disease (TOAD)
Status: COMPLETED
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: Oxaloacetate (OAA) 1g|DRUG: Oxaloacetate (OAA) 2g
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human rhPTH(1-34) VS Association Alfacalcidol/Hydrochlorothiazide in Severe Primary Hypoparathyroidism
Status: COMPLETED
Conditions: Autosomal Dominant Hypocalcemia OR Primary Hypoparathyroidism Related to Other Cause But Complicated by Hypercalciuria Under Treatment
Interventions: DRUG: Teriparatide|DRUG: Thiazide|DRUG: Potassium sparing diuretic|DRUG: Alfacalcidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Olfactory Training on Postoperative Delirium in the Elderly Undergoing Orthopedic Surgeries
Status: NOT_YET_RECRUITING
Conditions: Preoperative Olfactory Training|Postoperative Delirium
Interventions: BEHAVIORAL: olfactory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Metabolic Syndrome|Cardiovascular Disease|Diastolic Dysfunction|Fatty Liver
Interventions: DRUG: Liraglutide|DRUG: Liraglutide - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Spinal Manipulation on Thigh Muscle Strength
Status: COMPLETED
Conditions: Subluxation of Joint of Lumbar Spine
Interventions: OTHER: Spinal Manipulation|OTHER: Sham Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: pBFS-guided cTBS Over the Superior Temporal Gyrus for Aphasia After Ischemic Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic|Aphasia
Interventions: DEVICE: active continuous Theta Burst Stimulation|DEVICE: sham continuous Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0313 Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Radiation Therapy Followed By Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: Cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy|BIOLOGICAL: Yttrium-90 ibritumomab tiuxetan|BIOLOGICAL: Indium-111 ibritumomab tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and PTK787 in Metastatic Breast Cancer Patients and Gynecological Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Endometrial Cancer|Cervical Cancer|Fallopian Tube Cancer|Peritoneal Cancer|Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: PTK787
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma
Status: COMPLETED
Conditions: Progression-free Survival|Overall Survival|Clinical Benefit Rate|Toxicity
Interventions: DRUG: Apatinib|DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of Docetaxel and ZD1839 Followed by Removal of the Prostate to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: ZD1839
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Placebo-Controlled, Study Assessing the Safety and Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Patients With Elevated Eye Pressure
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: SBI-100 Ophthalmic Emulsion, 0.5%|DRUG: SBI-100 Ophthalmic Emulsion, 1.0%|DRUG: SBI-100 Ophthalmic Emulsion, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Phenotype Study in Patients With Obstructive Sleep Apnea Syndrome
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome|Hypertension
Interventions: DEVICE: Positive airway pressure treatment|OTHER: No positive airway pressure treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intracellular Phosphate Concentration Evolution During Hemodialysis by MR Spectroscopy
Status: COMPLETED
Conditions: End-Stage Renal Disease (ESRD)
Interventions: DEVICE: Phosphorus (31P) magnetic resonance spectroscopy|OTHER: Hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Dexmedetomidine on Stress Response and Emergence Agitation During Laparoscopic Surgery
Status: COMPLETED
Conditions: Stress Response
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy in Chinese Participants With Acute Myeloid Leukemia in Complete Remission
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: CC-486|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Package to Reduce HIV and AIDS-related Death in Zambia
Status: COMPLETED
Conditions: HIV/AIDS|Transitions of Care|Hospitalization|Tuberculosis|HIV Testing|Cryptococcosis
Interventions: DIAGNOSTIC_TEST: Inpatient lab bundling|BEHAVIORAL: Inpatient navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-inferiority Study of ZK-A03 in Treatment of Herpes Zoster Before and After the Alteration of the Active Ingredient Manufacturer
Status: NOT_YET_RECRUITING
Conditions: Herpes Zoster
Interventions: DRUG: Recombinant Human Interferon α-2b Gel (After the Alteration)|DRUG: Recombinant Human Interferon α-2b Gel (Before the Alteration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tracking Endothelial Cells in Arterial Injury
Status: COMPLETED
Conditions: Endothelial Progenitor Cells|Coronary Artery Disease|Vascular Injury|Coronary Angiography
Interventions: BIOLOGICAL: Administration of radio labelled endothelial outgrowth cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Suprapatellar Versus Infrapatellar Nailing in Tibial Fractures: A Pilot Study
Status: COMPLETED
Conditions: Tibial Fractures
Interventions: PROCEDURE: Suprapatellar approach|PROCEDURE: Infrapatellar approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Deoxycholic Acid Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Colonoscopy Non-attendance and the Efficacy of a SMS Reminder to Reduce Non-attendance Rate
Status: COMPLETED
Conditions: Ultilization of Out-patient Colonoscopy Service
Interventions: OTHER: SMS reminder|OTHER: Non-SMS reminder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Didanosine (ddI)|DRUG: Efavirenz (EFV)|DRUG: Emtricitabine (FTC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Long-term Outcome of Dorsal Ligamentoplasty Reinforced With an Internal Brace in the Treatment of Scapholunate Instability
Status: RECRUITING
Conditions: Wrist Disease
Interventions: PROCEDURE: Dorsal ligamentoplasty reinforced with an internal brace
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clarithromycin-based Triple Therapy for 14 Days Versus Sequential Therapy 10 Days in the First Line Therapy
Status: UNKNOWN
Conditions: Eradication Rates of the Two Regimens
Interventions: DRUG: D1-D5: (lansoprazole + amoxicillin ) D6-D10: (lansoprazole+clarithromycin +metronidazole)|DRUG: D1-D14: (lansoprazole + clarithromycin + amoxicillin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DKB-119 in Patients in Crow's Feet
Status: ACTIVE_NOT_RECRUITING
Conditions: Crow's Feet
Interventions: DEVICE: DKB-119
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Viral Load and Maternal-fetal Serology in the Interpretation of the Vertical Transmission of SARS Cov-2 (COVID-19) During Pregnancy
Status: COMPLETED
Conditions: Sars-CoV2
Interventions: DIAGNOSTIC_TEST: biological samples day of delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Dense Chemotherapy + Rituximab +/-Intensified High Dose Chemoimmunotherapy With Support of Peripheral Autologous Stem Cell in Diffuse Large B-Cell Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-Cell Lymphoma|IPI≥2
Interventions: DRUG: Rituximab|DRUG: Ciclofosfamide|DRUG: Doxorubicina|DRUG: Vincristina|DRUG: Prednisone|DRUG: Pegfilgrastim|DRUG: Mitoxantrone|DRUG: ARA-C|DRUG: Lenograstim|DRUG: BCNU|DRUG: ARA-C|DRUG: VP-16|PROCEDURE: ASCT|DRUG: Ciclofosfamide|DRUG: Doxorubicina|DRUG: Vincristina
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Obstructive SAS on Metastatic Potential of Cutaneous Melanoma
Status: WITHDRAWN
Conditions: Melanoma With a Breslow's Thickness ≥ 1mm|Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: nocturnal oximetry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy
Status: UNKNOWN
Conditions: Peptic Ulcer|Gastric Cancer|Esophagus Cancer|Oesophagitis|Hypoxia
Interventions: DEVICE: WEI NASAL JET|DEVICE: Nasopharyngeal airway without jet ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy
Status: TERMINATED
Conditions: Pleural Effusion
Interventions: DRUG: normal saline|DRUG: TNK (Tenecteplase)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgery for Ponto Bone Anchored Hearing Implants
Status: COMPLETED
Conditions: Conductive Hearing Loss|Unilateral Partial Deafness|Mixed Conductive-sensorineural Hearing Loss
Interventions: PROCEDURE: Surgery for Ponto bone anchored hearing aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glycemic Control Of Carvedilol Versus Metoprolol In Patients With Type II Diabetes Mellitus And Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: carvedilol|DRUG: metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Safety|Tolerability|Pharmacokinetics
Interventions: DRUG: RHN-001 (one tablet 750mg)|DRUG: RHN-001 (750mg * 2 Tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Supplementation of Oil Palm Phenolics to Improve Lipid Profile in Subjects With Minor Hyperlipidaemia
Status: COMPLETED
Conditions: Hyperlipidemias|Hypercholesterolemia
Interventions: DRUG: Placebo|DIETARY_SUPPLEMENT: 250 mg OPP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Targeting Food Aid to Malnourished Children Compared to Targeting All Children Under Two Years
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Fortified food rations|BEHAVIORAL: Education and communication to improve feeding practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.
Status: COMPLETED
Conditions: Ischaemic Heart Disease|Aortic Stenosis
Interventions: DRUG: Remifentanil|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD
Status: ACTIVE_NOT_RECRUITING
Conditions: End-stage Renal Disease|Kidney Failure, Chronic
Interventions: DEVICE: HAVG graft implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Fibrillation New Onset
Interventions: DEVICE: Cryoablation|DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Insomnia Intervention to Reduce Alcohol Use
Status: RECRUITING
Conditions: Alcohol Use Disorder|Heavy Drinking
Interventions: BEHAVIORAL: SHUTi Intervention|BEHAVIORAL: Web-Based Insomnia Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid in Children (1 -17 Years) With Severe Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serious Games for Training in Oral Rehabilitation
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice
Interventions: DEVICE: Playing Serious Games during a four-week test period in addition to conventional lectures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MF and CMML (HSCT 002)
Status: RECRUITING
Conditions: Myelofibrosis|Chronic Myelomonocytic Leukemia|Acute Myeloid Leukemia
Interventions: DRUG: Tagraxofusp
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Treatments for Ovarian Cancer: Standard Chemotherapy Plus Enzastaurin, or Placebo ("Sugar Pill")
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Neoplasms|Peritoneal Neoplasm
Interventions: DRUG: enzastaurin|DRUG: carboplatin|DRUG: paclitaxel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topotecan, Cisplatin and Bevacizumab for Recurrent/Persistent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Topotecan|DRUG: Cisplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy Participants
Status: COMPLETED
Conditions: Immunity Disorders
Interventions: DIETARY_SUPPLEMENT: N-Acetyl-L-cysteine (NAC)|DIETARY_SUPPLEMENT: Echinacea purpurea|DIETARY_SUPPLEMENT: Curcumin|DIETARY_SUPPLEMENT: Palmitoylethanolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Response to Phenylketonuria to Tetrahydrobiopterin (BH4)
Status: TERMINATED
Conditions: Phenylketonuria
Interventions: DRUG: tetrahydrobiopterin (BH4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Synaquell on Brain Function of Ice Hockey Players
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Synaquell|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a Kappa Agonist on Hot Flashes in Menopausal Women
Status: COMPLETED
Conditions: Treatment of Menopausal Hot Flashes
Interventions: DRUG: Standard Dose Kappa Agonist|DRUG: Half Dose Kappa Agonist|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Rehabilitation Protocol for Patients With PPPD
Status: NOT_YET_RECRUITING
Conditions: Rehabilitation|Balance|Vestibular Disorder|Dizziness
Interventions: OTHER: Interactive Visuo-Vestibular training|OTHER: Vestibular rehabilitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)
Status: COMPLETED
Conditions: Alagille Syndrome
Interventions: DRUG: LUM001 (Maralixibat)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety
Interventions: DRUG: Saredutant|DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Compliance and Evolution of Functional Capacity of Patients With Rheumatoid Arthritis Treated by Methotrexate Either by Auto-injector or by Conventional Sub-cutaneous Syringe
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cluster RCT - Evaluating Effectiveness of a Guide and Tools for Influenza Immunization Campaign Planners
Status: UNKNOWN
Conditions: Influenza
Interventions: BEHAVIORAL: Intervention Group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extracorporeal Shockwave Therapy for the Treatment of Advanced Angina Pectoris
Status: COMPLETED
Conditions: Refractory Angina Pectoris
Interventions: DEVICE: Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Depression in Parkinson's Disease
Status: UNKNOWN
Conditions: Depression in Parkinson's Disease
Interventions: DRUG: Xiaoyao Pill|DRUG: Bupleurum+Ginkgo|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Subcuticular Staples Versus Subcuticular Suture for Cesarean Section Skin Closure
Status: COMPLETED
Conditions: Surgical Wound
Interventions: DEVICE: Subcuticular suture|DEVICE: Subcuticular staple
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of SNF, Cash and BCC to Prevent Stunting Among Children 6-24 Months in Rahim Yar Khan, Pakistan
Status: COMPLETED
Conditions: Stunting
Interventions: DIETARY_SUPPLEMENT: SNF (Wawamum)|BEHAVIORAL: Social and behaviour change communication (SBCC)|OTHER: Cash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surgical Pulmonary Vein Isolation Efficiency Study
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation|Coronary Artery Disease
Interventions: PROCEDURE: CABG, AVR or CABG+AVR and PVI|PROCEDURE: CABG, AVR or CABG+AVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
Status: COMPLETED
Conditions: Recurrent Acute Leukemia of Ambiguous Lineage|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Lymphoblastic Leukemia|Refractory Acute Myeloid Leukemia|Refractory Acute Leukemia of Ambiguous Lineage
Interventions: OTHER: Chemosensitivity Assay|OTHER: Cytology Specimen Collection Procedure|GENETIC: Gene Expression Analysis|GENETIC: Genetic Variation Analysis|DRUG: In Vitro Sensitivity-Directed Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Metronomic Capecitabine With Camrelizumab for Treatment of Refractory Solid Tumor Trial (Cohort 2)
Status: UNKNOWN
Conditions: Head and Neck Cancer|Esophageal Squamous Cancer
Interventions: DRUG: Capecitabine, Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Interactive Internet-based Education and Counseling for the Management of Acne With That of Internet-based Education Alone
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: BEHAVIORAL: Virtual Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Propolis as a Treatment for Cervical Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dental Root Sensitivity
Interventions: COMBINATION_PRODUCT: desensitizing agents -10% Propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Epigenetic And Immune Therapy to Beat Cancer.
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Colorectal Carcinoma|Advanced Soft-tissue Sarcoma|Advanced Pancreatic Adenocarcinoma|Adult Solid Tumor
Interventions: DRUG: Durvalumab|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Lactobacillus Reuteri and Oral Microbiota
Status: COMPLETED
Conditions: Dental Plaque
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938 and PTA 5289|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Subtenon's Block With Olive Tipped Cannula
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: subtenon block|DEVICE: subtenon block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sensorimotor Training Using Whole Body Vibration Exercise to Reduce Chemotherapy-induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Breast Neoplasm, Exercise
Interventions: OTHER: Whole Body Vibration exercise - WBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cutaneous Microcirculation After Plasma Therapy
Status: COMPLETED
Conditions: Burn Injury|Acute Wound|Chronic Wound|Burn Scar
Interventions: DEVICE: Plasma Therapy (PlasmaDerm)|DEVICE: Repetitive Plasma Therapy (repetitive PlasmaDerm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of High Dosage CIFN Plus RBV for HCV Genotype 1 Infected Patients Who Are Nonresponders to Prior Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Interferon Alfacon-1 and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Faslodex With or Without Concomitant Arimidex Versus Exemestane Following Progression on Non-steroidal Aromatase Inhibitors (NSAI)
Status: COMPLETED
Conditions: Progression-free Survival
Interventions: DRUG: fulvestrant|DRUG: anastrozole|DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the PK, Relative Bioavailability and Safety of TG-2349 With Single Oral Dose Under Fed Condition in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TG-2349 as the original formulation|DRUG: TG-2349 as a new capsule formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms by Site
Interventions: BIOLOGICAL: nivolumab|DRUG: rHuPH20|BIOLOGICAL: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Ascending Dose Escalation to Investigate Safety and PK of VVZ-149 Injection in Healthy Older Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: VVZ-149 injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Glucosamine Sulfate and Chondroitin Sulfate Combination in Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: glucosamine sulfate /chondroitin sulfate - capsules|DRUG: glucosamine sulfate /chondroitin sulfate - sachet|DRUG: Cosamin DS®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of Multi-Detector Spiral Computed Tomography Angiography Using 64 Detectors
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: Multidetector Computed Tomography - 64 detectors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults
Status: COMPLETED
Conditions: Lateral Canthal Lines|Crow's Feet|Facial Wrinkles
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo (Dose B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified BEAM Regimen for T Cell Lymphoma Underwent ASCT
Status: NOT_YET_RECRUITING
Conditions: Autologous Stem Cell Transplantation|Conditioning
Interventions: DRUG: modified BEAM|DRUG: BEAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Shuhua Milk Fortified With Plant Sterol Esters on Serum Cholesterol in Human
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Milk fortified with plant sterol esters|DIETARY_SUPPLEMENT: Plain milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck|Melanoma|Non Small Cell Lung Cancer|Urothelial Carcinoma|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Squamous Cell Carcinoma of the Anus|Squamous Cell Carcinoma of the Cervix|Squamous Cell Carcinoma of the Skin|Renal Cell Carcinoma|Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma|Mismatch Repair Deficient or MSI-High Solid Tumors
Interventions: DRUG: SL-279252
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot-controlled Magnet-Assisted Capsule Endoscopy
Status: RECRUITING
Conditions: Abdominal Pain|Upper Gastrointestinal Symptoms
Interventions: DIAGNOSTIC_TEST: Magnet Assisted Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Coronary In-Stent Restenosis by a Sirolimus (Rapamycin) Coated Balloon or a Paclitaxel Coated Balloon
Status: COMPLETED
Conditions: DES In-stent Stenosis
Interventions: DEVICE: Paclitaxel coated balloon (SeQuent Please)|DEVICE: Sirolimus coated balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Accuracy of Conventional Versus Digital Implant Impression Techniques
Status: UNKNOWN
Conditions: Missing Teeth
Interventions: OTHER: digital impression for normal abutment|OTHER: open tray impression|OTHER: closed tray impression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RHCACD20MA (HS006) Combined With CHOP (Hi-CHOP) in Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: HS006+CHOP|DRUG: HS006+CHOP|DRUG: Rituximab+CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems
Status: UNKNOWN
Conditions: Overweight|Abnormal Liver Function Tests
Interventions: DRUG: Ursodeoxycholic acid|DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Calorie Diet in People With Prediabetes/Metabolic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Obesity|NAFLD|Fatty Liver|Pre Diabetes|Metabolic Syndrome
Interventions: OTHER: Standard of care|DIETARY_SUPPLEMENT: Low-calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Different Manual Therapy Techniques in Patients With Cervical Spondylosis
Status: COMPLETED
Conditions: Cervical Spondylosis
Interventions: OTHER: Conventional physiotherapy|OTHER: Conventional physiotherapy and Muscle Energy Technique|OTHER: Conventional physiotherapy and Cervical Mobilization Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men
Status: NOT_YET_RECRUITING
Conditions: Premature Ejaculation|Stress
Interventions: OTHER: Destress and Perform Capsule-U001|OTHER: Destress and Perform Capsule-I001|OTHER: Placebo capsules 002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LUME-Ovar 1: Nintedanib (BIBF 1120) or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Placebo|DRUG: Paclitaxel|DRUG: BIBF 1120|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Novel Use of 2-unit Cantilever Resin-bonded Bridges for Replacing Missing Molar Teeth - a Randomized Clinical Trial
Status: COMPLETED
Conditions: Missing Teeth
Interventions: PROCEDURE: 2-unit cantilevered resin bonded bridge|PROCEDURE: 3-unit fixed movable resin bonded bridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effects of Photobiomodulation on Clinical Recovery From Concussion in Adolescents
Status: RECRUITING
Conditions: Sports-related Concussion
Interventions: DEVICE: Photobiomodulation therapy (PBMt)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docosahexaenoic Acid (DHA) Administration and Length of Gestation: a Feasibility Study
Status: WITHDRAWN
Conditions: Premature Birth
Interventions: DIETARY_SUPPLEMENT: docosahexaenoic acid (DHA)|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Antrodia Cinnamomea Mycelia on Improving Immune Response in Subhealth People
Status: COMPLETED
Conditions: Fatigue Syndrome, Chronic|Cold
Interventions: DIETARY_SUPPLEMENT: Antrodia cinnamomea mycelia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dental Autotransplantation or Immediate Single Implant for the Replacement of a Hopeless Molar.
Status: COMPLETED
Conditions: Transplantation, Autologous|Autografts|Surgery, Oral
Interventions: PROCEDURE: Tooth Autotransplantation|PROCEDURE: Immediate implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Which Technique is Effective in Reducing the Pain of Peripheral Intravenous Catheterization in Pediatric Patients, Infra-Red Light or Buzzy®?
Status: UNKNOWN
Conditions: Pain Management
Interventions: DEVICE: The Buzzy®|DEVICE: The AccuVein®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of the Anesthetic Drug Propofol on the Way the Heart Recovers Between Beats
Status: COMPLETED
Conditions: Myocardial Repolarization
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF +SCTG|OTHER: platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT