pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Evaluate the Efficacy and Safety of Filgotinib in the Treatment of Small Bowel Crohn's Disease (SBCD)
Status: COMPLETED
Conditions: Small Bowel Crohn's Disease
Interventions: DRUG: Filgotinib|DRUG: Placebo to match filgotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Cost-efficacy of Psychological Intervention for Strengthening Parental Authority Among Parents of Diabetic Adolescents With Poor Glycemic Control
Status: COMPLETED
Conditions: Diabetes
Interventions: BEHAVIORAL: psychological intervention|BEHAVIORAL: Diabetes education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baby's First Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Child Development|Brain Development|Household and Family Processes
Interventions: BEHAVIORAL: Monthly cash gift payments of $333|BEHAVIORAL: Monthly cash gift payments of $20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Alendronate, Calcium, and Vitamin D on Bone Mineral Density in HIV Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Alendronate|DRUG: Calcium carbonate|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma
Status: RECRUITING
Conditions: Retinoblastoma|Cataracts Infantile|Glaucoma, Congenital|Leucocoria
Interventions: OTHER: CRADLE|OTHER: Red reflex testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of InteguSeal for Surgical Skin Preparation in Patients Undergoing Total Joint Replacement
Status: COMPLETED
Conditions: Prosthetic Joint Infection|Surgical Skin Infection
Interventions: DEVICE: Integuseal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fuzeon (Enfuvirtide) Early Access Program for Patients With HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide T/20/Ro 29,9800, HIV-1 Infusion Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: RADIATION: Radiation|DRUG: Aflibercept|PROCEDURE: Surgery|DRUG: FOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Islet Transplantation in Brittle Type 1 Diabetes Mellitus. The GRAGIL 2 Study.
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: human pancreatic islet transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Active Vitamin D, ED-71 for Osteoporosis
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: ED-71|DRUG: Alfacalcidol|DRUG: ED-71 placebo|DRUG: Alfacalcidol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab in Combination With Glofitamab and Polatuzumab Vedotin in Patients With Previously Untreated Aggressive B-cell Lymphoma Ineligible for R-CHOP
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Glofitamab|DRUG: Rituximab|DRUG: Obinutuzumab|DRUG: Polatuzumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cell Transplantation for Lupus Nephritis
Status: UNKNOWN
Conditions: Lupus Nephritis
Interventions: BIOLOGICAL: SLE group|BIOLOGICAL: LN group|OTHER: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dry Needling Compared to Lumbar Spine Mobilization in Patients With Chronic Non Specific Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Dry needling|OTHER: Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sumamos Excelencia 2022
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Incontinence, Urinary|Obesity, Childhood|Breastfeeding
Interventions: OTHER: Continuous quality improvement cycle model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nab-Paclitaxel Plus Cisplatin With Concurrent Radiotherapy for Patients With Locally Advanced Cervical Cancer: A Multicentre, Single-arm, Phase II Trial.
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: RADIATION: radiotherapy|DRUG: Nab paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mindfulness Based Cognitive Therapy on Emotional Processing
Status: UNKNOWN
Conditions: Unipolar Depression|Anxiety Disorders|Adjustment Disorders|Emotional Instability
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentration of Ofloxacin Into the Aqueous Humour of Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Oxatrex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Randomized Study of TransAeris® System in Cardiac Surgery Patients at Risk of Prolonged Mechanical Ventilation
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventilator Induced Diaphragm Dysfunction
Interventions: DEVICE: TransAeris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Preliminary Exploratory Cohort Study of COVID-19 mRNA Vaccine, Bivalent in Participants Aged 18 Years and Over in China
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: COVID-19 Variant (Omicron BA.5) mRNA Vaccine Low dose|BIOLOGICAL: COVID-19 Variant (Omicron BA.5) mRNA Vaccine High dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association With Disease Stage
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Prostate Inflammation
Interventions: PROCEDURE: Prostate biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cattell-Warren Versus Blumgart Techniques of Pancreatico-jejunostomy Following Pancreato-duodenectomy
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Blumgart Anastomosis|PROCEDURE: Cattell-Warren Anastomosis|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Time-restricted Eating on Behaviour and Metabolism in Overweight Individuals at High Risk of Type 2 Diabetes
Status: COMPLETED
Conditions: Overweight and Obesity|PreDiabetes
Interventions: OTHER: Time-restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stem Cell Transplant in Patients With Severe Sickle Cell Disease
Status: TERMINATED
Conditions: Sickle Cell Disease
Interventions: DRUG: Alemtuzumab|RADIATION: Total Body Irradiation|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of YHP1701
Status: COMPLETED
Conditions: Hypertension and Hyperlipidemia
Interventions: DRUG: YHP1701|DRUG: YHR1703|DRUG: YHR1704
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Caries Management: Clinical Study
Status: UNKNOWN
Conditions: Caries,Dental|Caries Arrested
Interventions: DEVICE: Resin Infiltration|DEVICE: Sodium Fluoride Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soft Tissue Mobilization Versus Therapeutic Ultrasound for Subjects With Neck and Arm Pain
Status: COMPLETED
Conditions: Cervical Radiculopathy
Interventions: OTHER: Soft Tissue Mobilization|DEVICE: Therapeutic Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Intervention to Minimize Disparities in Humanpapillomavirus Vaccination
Status: COMPLETED
Conditions: HPV Vaccination Status
Interventions: BEHAVIORAL: Tailored educational materials|BEHAVIORAL: Untailored educational materials|BEHAVIORAL: Survey-only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable
Status: NOT_YET_RECRUITING
Conditions: Colorectal Polyp|Colorectal Cancer
Interventions: OTHER: Learning tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Germline DNA-Based Radiosensitivity Biomarker Influence on Toxicity Following Prostate Radiotherapy, GARUDA Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma|Stage I Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8
Interventions: PROCEDURE: Discussion|RADIATION: Hypofractionated Radiation Therapy|RADIATION: Hypofractionated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Modified Fixed Twin Block Versus Removable Twin Block on Skeletal Class 2 Growing Patients With Mandibular Deficiency
Status: RECRUITING
Conditions: Malocclusion|Angle Class II|Mandible Small
Interventions: DEVICE: modified Fixed twinblock|DEVICE: removable twin block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Examining Changes in Pain After Manual Therapy in People With Achilles Tendon Pain
Status: RECRUITING
Conditions: Achilles Tendinopathy|Ankle Strain|Achilles Tendon Pain|Achilles Tendonitis
Interventions: PROCEDURE: Ankle mobilization|PROCEDURE: Sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors
Status: RECRUITING
Conditions: Neuroendocrine Tumors|NET|Pancreatic Neuroendocrine Tumor|Gastrointestinal Neuroendocrine Tumor|Pulmonary Neuroendocrine Tumor
Interventions: DRUG: nab-sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies
Status: UNKNOWN
Conditions: Hematologic Malignancy|Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myeloproliferative Neoplasm|Chronic Myeloid Leukemia
Interventions: BIOLOGICAL: CD123-CD33 cCAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine on Early Cognitive Dysfunction in Shoulder Arthroscopy
Status: UNKNOWN
Conditions: Cognitive Dysfunction, Postoperative
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Switching From Efavirenz to Atazanavir/ Ritonavir in HIV-infected Subjects With Good Virologic Suppression
Status: TERMINATED
Conditions: HIV Infection|Mitochondrial Dysfunction
Interventions: DRUG: Atazanavir/ritonavir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: Leukocyte-Poor Platelet Rich Plasma (LP-PRP)|BIOLOGICAL: Bone Marrow Concentrate (BMC)|OTHER: Control group (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity
Status: TERMINATED
Conditions: Ototoxic Hearing Loss|Ototoxic Hearing Loss, Bilateral|Ototoxicity|Tinnitus
Interventions: DRUG: N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lid Wiper Epitheliopathy Trial
Status: TERMINATED
Conditions: Lid Wiper Epitheliopathy
Interventions: DEVICE: Spectacles|DEVICE: Delefilcon A contact lenses|DEVICE: Etafilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults With Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: cognitive behaviorial therapy -Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid Lowering Effect of Plant Stanol Ester in a Drinkable Non-dairy Product
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: OTHER: Plant stanol ester|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tandem High Dose Chemotherapy With 131I-MIBG Treatment in High Risk Neuroblastoma
Status: UNKNOWN
Conditions: High Risk Neuroblastoma
Interventions: DRUG: Cyclophosphamide|DRUG: Carboplatin|DRUG: Etoposide|RADIATION: 131I-MIBG|DRUG: Thiotepa|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: THS 2.2 Menthol (mTHS 2.2)|OTHER: Menthol Conventional Cigarette (mCC)|OTHER: Smoking Abstinence (SA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of Laser Acupuncture on Taxane Acute Pain Syndrome Patients
Status: TERMINATED
Conditions: Pain Cancer|Joint Pain
Interventions: DEVICE: Laser acupuncture device|DEVICE: Pseudo-laser acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Losartan and Hypofractionated Rx After Chemo for Tx of Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (SHAPER)
Status: RECRUITING
Conditions: Borderline Resectable Pancreatic Adenocarcinoma|Locally Advanced Pancreatic Ductal Adenocarcinoma|Locally Advanced Unresectable Pancreatic Adenocarcinoma|Stage II Pancreatic Cancer AJCC v8|Stage IIA Pancreatic Cancer AJCC v8|Stage IIB Pancreatic Cancer AJCC v8|Stage III Pancreatic Cancer AJCC v8
Interventions: RADIATION: Hypofractionated Radiation Therapy|DRUG: Losartan|DRUG: Losartan Potassium|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in T-cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, T-Cell, Peripheral|Lymphoma, T-Cell, Cutaneous
Interventions: DRUG: RP6530
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel and TLK286 (Telcyta) as First-Line Therapy in Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: TLK286|DRUG: carboplatin|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Rituximab for the Treatment of Marginal Zone Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|MALT Lymphoma
Interventions: DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion
Status: RECRUITING
Conditions: Basilar Artery Occlusion|Acute Cerebrovascular Accident|Stroke Due to Basilar Artery Occlusion
Interventions: DRUG: Tenecteplase|PROCEDURE: Endovascular thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dichoptic Virtual Reality Therapy for Amblyopia in Adults
Status: TERMINATED
Conditions: Amblyopia|Anisometropia|Strabismus
Interventions: DEVICE: Dichoptic therapy|OTHER: Patching therapy|DEVICE: Dioptic (non-dichoptic) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Cavitation on Static and Dynamic Balance in Obese Postnatal Women With Diastasis Recti
Status: COMPLETED
Conditions: Rectus Diastasis
Interventions: OTHER: low caloric diet regimen|DEVICE: ultrasound cavitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Qure Study: Q-fever Fatigue Syndrome - Response to Treatment
Status: COMPLETED
Conditions: Q Fever|Fatigue Syndrome, Chronic|Coxiella Infection
Interventions: BEHAVIORAL: Cognitive behavioral therapy|DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-fat Challenge Induced Trained Innate Immunity (SHAKE Study)
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: High-fat shake|DIETARY_SUPPLEMENT: Reference shake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Substudy 01 - Safety and Immunogenicity of One Monovalent Modified mRNA Vaccine Encoding Influenza Hemagglutinin With LNP, in Adult Participants Aged 18 to 49 Years and 60 Years and Above
Status: COMPLETED
Conditions: Influenza Immunization
Interventions: BIOLOGICAL: H3 mRNA / LNP Vaccine|BIOLOGICAL: Quadrivalent recombinant influenza Vaccine (RIV4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lung-MAP: Talazoparib in Treating Patients With HRRD Positive Recurrent Stage IV Squamous Cell Lung Cancer
Status: COMPLETED
Conditions: ATM Gene Mutation|ATR Gene Mutation|BARD1 Gene Mutation|BRCA1 Gene Mutation|BRCA2 Gene Mutation|BRIP1 Gene Mutation|CHEK1 Gene Mutation|CHEK2 Gene Mutation|FANCA Gene Mutation|FANCC Gene Mutation|FANCD2 Gene Mutation|FANCF Gene Mutation|FANCM Gene Mutation|NBN Gene Mutation|PALB2 Gene Mutation|RAD51 Gene Mutation|RAD51B Gene Mutation|RAD54L Gene Mutation|Recurrent Squamous Cell Lung Carcinoma|RPA1 Gene Mutation|Stage IV Squamous Cell Lung Carcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Granulocyte Colony Stimulating Factor (G-CSF) on Myocardial Function After Acute Anterior Myocardial Infarction, a Prospective Double Blind Randomized Placebo Controlled Study
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: G-CSF|DRUG: placebo infusion of normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3)
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: High-dose rifampicin|DRUG: Isoniazid|DRUG: Pyrazinamide|DRUG: Ethambutol|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride in Treating Patients With Advanced or Refractory Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Pazopanib Hydrochloride|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Donor Whole Blood for Blood Transfusion in Deceased Donor Liver Transplantation
Status: WITHDRAWN
Conditions: Transfusion Related Complication|Liver Transplant
Interventions: BIOLOGICAL: Donor Blood|BIOLOGICAL: Banked Blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Socket Interface Design on Socket Comfort, Residual Limb Health, and Function for the Transfemoral Amputee
Status: COMPLETED
Conditions: Amputation
Interventions: DEVICE: Ischial Ramus Containment (IRC)|DEVICE: Dynamic Socket Ischial Ramus Containment (IRC)|DEVICE: Sub-Ischial Interface (Sub-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive Patients
Status: COMPLETED
Conditions: Abdominal Obesity|Hypertension
Interventions: DRUG: Carvedilol CR + Lisinopril|DRUG: Lisinopril + HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Setmelanotide in Acquired Hypothalamic Obesity
Status: ENROLLING_BY_INVITATION
Conditions: Hypothalamic Obesity
Interventions: DRUG: Setmelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and Thymalfasin for Locally Advanced Mid-low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DRUG: Thymalfasin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of the Myofascial Trigger Point Injections on Pain and Sleep Disturbance in Patients With Nocturnal Leg Cramps With Trigger Points on Gastrocnemius Muscle
Status: COMPLETED
Conditions: Nocturnal Leg Cramps
Interventions: PROCEDURE: Myofascial trigger point injections on gastrocnemius muscle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of BIIB091, a Bruton's Tyrosine Kinase (BTK) Inhibitor, in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BIIB091|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Passiflora Incarnata L; Crataegus Oxyacantha L and Salix Alba L. on Mild and Moderate Anxiety
Status: COMPLETED
Conditions: Anxiety Disorder
Interventions: DRUG: Passiflora ; Crataegus and Salix|DRUG: Valeriana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Donepezil HCl in Subjects Receiving Haemodialysis.
Status: COMPLETED
Conditions: End-Stage Renal Disease
Interventions: DRUG: donepezil HCl|DRUG: donepezil HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrical Stimulation Parameters on Torque, Fatigue, and Oxygen Extraction
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Russian current 10%|OTHER: Russian current 20%|OTHER: Aussie current 10%|OTHER: Aussie current 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Development of a Mobile-based App to Increase Uptake of Pre-Exposure Prophylaxis (PrEP) by Men Who Have Sex With Men in China
Status: COMPLETED
Conditions: HIV|Pre-exposure Prophylaxis
Interventions: BEHAVIORAL: Phone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: High-frequency oscillation|DEVICE: Conventional lung-open mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II/III Clinical Trial of Recombinant Human Serum Albumin in Cirrhotic Patients With Ascites
Status: NOT_YET_RECRUITING
Conditions: Cirrhotic Ascites
Interventions: DRUG: Recombinant Human Serum Albumin|DRUG: Human Serum Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Survivin Vaccine|PROCEDURE: Autologous Hematopoietic Cell Transplantation|BIOLOGICAL: Prevnar 13|DRUG: Granulocyte-colony Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulse CONtour and BIoimpedance for Measurements of Stroke Volume During Changes in CARdiac Preload
Status: COMPLETED
Conditions: Hemodynamic, Monitoring|Anesthesia|Blood Pressure
Interventions: DEVICE: CLEARSIGHT and NICCOMO measurements in sequence A|DEVICE: CLEARSIGHT and NICCOMO measurements in sequence B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Versus Suboccipital Direct Current Stimulation
Status: COMPLETED
Conditions: Pain|Transcranial Direct Current Stimulation
Interventions: DEVICE: Direct Current Stimulation|DEVICE: Sham DCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Smart-phone Based Support System for Hazardous Drinkers
Status: COMPLETED
Conditions: Alcohol Consumption
Interventions: OTHER: NZ Step Away app|OTHER: Modified NZ Step Away app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I and Pharmacokinetic Study of Mitoxantrone Hydrochloride Liposome Injection
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bowel ENDOmetriosis; Evaluation of Diagnostics and Quality of Life
Status: COMPLETED
Conditions: Endometriosis Related Pain|Quality of Life|Pain, Chronic|Bowel Dysfunction|Endometriosis Rectum|Deep Infiltrating Endometriosis|Deep Endometriosis
Interventions: PROCEDURE: 2D transvaginal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients
Status: COMPLETED
Conditions: Depression|Epilepsy, Temporal Lobe
Interventions: OTHER: Cognitive behavioral therapy|DRUG: SSRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota in Chronic Noncommunicable Diseases
Status: COMPLETED
Conditions: Arterial Hypertension|Atherosclerosis Occlusive Disease|Heart Failure With Preserved Ejection Fraction|Heart Failure With Reduced Ejection Fraction|Diabetes Mellitus, Type 2|Obstructive Pulmonary Disease|Asthma|Nonalcoholic Fatty Liver Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination in Participants With Chronic Genotype 1 HCV Infection
Status: COMPLETED
Conditions: Chronic HCV Infection
Interventions: DRUG: LDV/SOF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Antibiotic Therapy for Pyelonephritis in Childhood
Status: TERMINATED
Conditions: Pyelonephritis
Interventions: DRUG: ceftibuten|DRUG: ceftibuten
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Duration of Untreated Psychosis Through Rapid Identification and Engagement
Status: TERMINATED
Conditions: Psychotic Disorders
Interventions: OTHER: Electronic Screen + Education (Phase 1)|OTHER: Targeted Provider Education (Phase 1)|OTHER: Community Mobile Engagement (Phase 2)|OTHER: Clinic based Engagement (Phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia
Status: UNKNOWN
Conditions: Tetraplegia|Hypothermia|Mild Cognitive Impairment
Interventions: DRUG: Midodrine Hydrochloride|OTHER: Cool Temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Probiotics in Childhood Abdominal Pain
Status: COMPLETED
Conditions: Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical Natural Baobab Oil in the Management of BCG-induced Lower Urinary Tract Symptoms
Status: COMPLETED
Conditions: Superficial Bladder Cancer|Lower Urinary Tract Symptoms
Interventions: DEVICE: Intravesical baobab oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Investigate the Safety and Efficacy of GWP42003-P Versus Placebo as Adjunctive Therapy in Participants With Schizophrenia Experiencing Inadequate Response to Ongoing Antipsychotic Treatment
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: GWP42003-P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Zometa|DRUG: zometa|DRUG: Zometa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RRx-001 Sequentially With a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond in Patients With Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Small Cell Lung
Interventions: COMBINATION_PRODUCT: RRx-001 + eLOOP Device|DRUG: Cisplatin/carboplatin plus etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Young Adult Pacific Islanders: Motivating Pacifika Against Cigarettes and Tobacco
Status: COMPLETED
Conditions: Tobacco Use|Tobacco Smoking|Tobacco Use Cessation|Smoking|Smoking Cessation|Smoking, Cigarette
Interventions: BEHAVIORAL: Motivating Pacifika Against Cigarettes and Tobacco
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does the Use of Prophylactic Mesh Reduce Incisional Hernia?
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: PROCEDURE: primary abdominal closure|DEVICE: abdominal closure with prophylactic mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab in Combination With Sintilimab Versus Transcatheter Arterial Chemoembolization for the Treatment of Intermediate Stage Hepatocellular Carcinoma (Beyond Up-To-Seven Criteria)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Bevacizumab combined with Sintilimab|PROCEDURE: Transcatheter arterial chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electronic Memory and Management Aid
Status: RECRUITING
Conditions: Subjective Cognitive Complaints|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Personalized Web-based training for EMMA app|BEHAVIORAL: Motivational Interviewing: Clinician Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Foot Reflexology on Pain, Comfort and Beta Endorphin Levels in Patients With Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplant; Complications
Interventions: OTHER: Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 50 Hz vs. 25 Hz Magnetic Seizure Therapy for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: PROCEDURE: 25 Hz magnetic seizure therapy|PROCEDURE: 50 Hz magnetic seizure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The University of Pennsylvania Uterus Transplant for Uterine Factor Infertility Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Mayer Rokitansky Kuster Hauser Syndrome|Uterine Agenesis|Infertility, Female, of Uterine Origin|Uterine Factor Infertility
Interventions: OTHER: Uterine Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring the Distribution Patterns and Infrared Characteristics of Force-sensitive Acupoints in Different Lumbar Nerve Segments in Patients With LDH Based on "Press Quickly" Theory
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: DIAGNOSTIC_TEST: Infrared thermal imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Dry Needling Technique in Hip Muscles in Subjects With Grade I-III Hip Osteoarthritis
Status: UNKNOWN
Conditions: Hip Osteoarthritis
Interventions: OTHER: Dry needling|OTHER: Sham Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamide
Status: RECRUITING
Conditions: Graft Vs Host Disease|Hematopoietic Neoplasm
Interventions: DRUG: Methotrexate Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)
Status: COMPLETED
Conditions: Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
Interventions: DRUG: Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-blind, Randomized, Placebo-controlled Trial of Ganaxolone in CDKL5 Deficiency Patients 6 Months to Less Than 2 Years Old
Status: NOT_YET_RECRUITING
Conditions: CDKL5 Deficiency Disorder
Interventions: DRUG: Ganaxolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Music Therapy on Reducing Delirium in Mechanically Ventilated Adults in Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness|Mechanical Ventilation
Interventions: OTHER: Personalized music|OTHER: Personalized music plus earplug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Holter Versus Zio Patch Electrocardiographic Monitoring in Children
Status: COMPLETED
Conditions: Arrhythmias, Cardiac|Heart Block
Interventions: DEVICE: Holter Monitor|DEVICE: Zio Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immune Response of Visceral Leishmaniasis PatientsTreated With Antimonial Plus N-Acetylcysteine
Status: UNKNOWN
Conditions: Visceral Leishmaniasis|Immune Response|Treatment
Interventions: DRUG: N-acetylcysteine|DRUG: Pentavalent antimonial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Assessment of Procedure-Related and Patient-Reported Outcomes After Retrograde Intrarenal Surgery (RIRS) for Renal Calculi Less Than 20 mm
Status: COMPLETED
Conditions: Renal Stone
Interventions: PROCEDURE: Retrograde Intrarenal Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Subcutaneous Doses of HIP2B in Subjects With Type 2 Diabetes Mellitus Treated With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HIP2B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazine Treated Sarcoma Patients (MGMT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma
Interventions: GENETIC: O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and MGMT expression on dacarbazine treated sarcoma patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Protein Supplementation Impact On Body Muscle Mass And Fat Mass In Qataris Post Bariatric Surgery, Randomized Controlled Trials (Rct)
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: (Cubitan Protein, Nutricia, Netherlands).|DIETARY_SUPPLEMENT: (preOp, Nutricia, Netherlands).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Manual Therapy in Chronic Shoulder Pain Treatment
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Mobilization to the glenohumeral joint|PROCEDURE: The manual contact condition|OTHER: No-contact condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Initial Human Validation of Simultaneous Dual-Tracer Cardiac PET Imaging
Status: COMPLETED
Conditions: Ischemic Heart Disease|Myocardial Infarction
Interventions: DRUG: Cardiac PET scan w/18F-Fluorodeoxyglucose and rubidium-82
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Wide Excision Alone as Treatment for Ductal Carcinoma in Situ of The Breast
Status: ACTIVE_NOT_RECRUITING
Conditions: Ductal Carcinoma in Situ of the Breast
Interventions: OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ketone Dose and Cerebral Blood Flow Study
Status: RECRUITING
Conditions: Cerebrovascular Function|Cognition
Interventions: DIETARY_SUPPLEMENT: Low Dose β-OHB|DIETARY_SUPPLEMENT: High Dose β-OHB|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: GBT440
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enfamil NeuroPro Study
Status: RECRUITING
Conditions: Infant Development|Infant ALL
Interventions: DIETARY_SUPPLEMENT: Enfamil NeuroPro|DIETARY_SUPPLEMENT: Enfamil Infant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Secukinumab in Tumor Necrosis Factor (TNF) - Inadequate Response (IR) Psoriasis Participants.
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Secukinumab (AIN457)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low and High Phytosterol Diets With Respect to Cholesterol Metabolism
Status: COMPLETED
Conditions: Hypercholesterolemia|Coronary Heart Disease
Interventions: OTHER: Low Phytosterol and High Phytosterol Diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Durvalumab and Tremelimumab, Administered With Radiation Therapy or Ablation in Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: durvalumab|DRUG: tremelimumab|RADIATION: Radiotherapy (RT)|PROCEDURE: ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Four Different Treatment Regimens of Helicobacter Pylori in Chinese Children
Status: RECRUITING
Conditions: Helicobacter Infections
Interventions: DRUG: triple therapy|DRUG: sequential therapy|DRUG: bismuth quadruple therapy|DRUG: concomitant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT