pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Trial Between the Intra-articular Local Anesthetic Infiltration With Catheter and Interscalene Block With Catheter in Postoperative Analgesia After Shoulder Prosthesis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: intra-articular local anesthetic infiltration|PROCEDURE: inter-scalene block|DRUG: Ropivacaine 2 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of ZS in Patients With Hyperkalemia.
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate 5g|DRUG: Sodium Zirconium Cyclosilicate 10g|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BLI801 Laxative in Constipated Adults
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: BLI801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Crenolanib besylate|DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Azacytidine|DRUG: Mitoxantrone|DRUG: Etoposide|DRUG: Fludarabine|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHIPs-VTE Study in Hospitalized Patients to Prevent Hospital-Acquired Venous Thromboembolism
Status: RECRUITING
Conditions: Venous Thromboembolic Disease|Pulmonary Embolism|Venous Thromboembolism|Deep Venous Thrombosis|Quality Improvement
Interventions: OTHER: The multifaceted interventions|OTHER: Routine VTE prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis
Status: UNKNOWN
Conditions: Sepsis, Septic Shock
Interventions: DRUG: Sodium Bicarbonate Ringer's Solution|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Cost-Effectiveness of Same-day Discharge Surgery for Primary Total Hip Arthroplasty
Status: UNKNOWN
Conditions: Hip Arthropathy
Interventions: PROCEDURE: the same-day discharge surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Case-Control Study of Negative Pressure Platform Wound Devices (NP-PWD) for Skin and Soft Tissue Defects
Status: COMPLETED
Conditions: Skin Wound|Soft Tissue Injuries
Interventions: DEVICE: NP-PWD|DEVICE: Wound Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Evaluating the Blood Glucose-lowering Effect of NN1250 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modified Constraint Induced Movement Therapy to Improve Lower Extremity Function in the Acute and Subacute Stroke Patients by Providing 1 Hour of Intense Massed Practice in the Form of Shaping or Task Practice
Status: WITHDRAWN
Conditions: Stroke
Interventions: OTHER: CIMT|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2881835 in Healthy People and People With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2881835|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial
Status: COMPLETED
Conditions: Cardiopulmonary Arrest|Respiratory Arrest
Interventions: DRUG: Etomidate|DRUG: Ketamine|PROCEDURE: Emergency Endotracheal Intubation|DEVICE: Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Small Lymphocytic Lymphoma
Interventions: DRUG: thalidomide|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Evaluation of GSK Biologicals' Pandemic Influenza Vaccine.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK1562902A|BIOLOGICAL: GSK1562902A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diabetes-Specific Nutritional Formulas Versus Oatmeal
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DIETARY_SUPPLEMENT: Oatmeal breakfast|DIETARY_SUPPLEMENT: Glucerna formula|DIETARY_SUPPLEMENT: Ultra Glucose Control formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Immunogenicity and Safety Study to Assess Influenza Vaccine Formulated With Haemagglutinin (HA) Antigen From Two Different Suppliers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Virosomal influenza vaccine (AdImmune HA Antigen)|BIOLOGICAL: Virosomal influenza vaccine (CSL HA Antigen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Development, Refinement, and Validation of a Peer Support Specialist Checklist for Individuals With Opioid Use Disorder / STAMPS: South Carolina Buprenorphine Treatment Initiation, Adherence, and Retention Utilizing Mobile Health Units and Peer Support Specialists
Status: RECRUITING
Conditions: Opioid Use Disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia
Status: COMPLETED
Conditions: Dysphonia Resulting From Vocal Fold Scarring|Age-related Dysphonia
Interventions: BIOLOGICAL: Azficel-T (autologous fibroblasts)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Distribution of Medication Disposal Packets - Acute Opioid Prescribing
Status: COMPLETED
Conditions: Orthopedic Surgery|Neurosurgery|Surgery|Opioid Use|Opioid Misuse
Interventions: OTHER: Medication Disposal Packet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Minimally Invasive Therapy Adjuvant to the Standards of Care by Cyanoacrylate Embolization
Status: RECRUITING
Conditions: Chronic Subdural Hematoma
Interventions: OTHER: Medical treatment|OTHER: Surgical treatment|OTHER: embolization of the MMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Major Neurocognitive Disorder With Aggressive Behavior
Interventions: DRUG: THC-free CBD Oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: [14C]-SK-1405
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Selective Exposure in HIV Prevention
Status: COMPLETED
Conditions: HIV Infections
Interventions: BEHAVIORAL: Maximal Control|BEHAVIORAL: Instrumental and Empowering|BEHAVIORAL: Minimal Control|BEHAVIORAL: Instrumental|BEHAVIORAL: Empowering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps
Status: RECRUITING
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: 300mg/600mg of TQH2722 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial
Status: RECRUITING
Conditions: Metastatic Papillary Renal Cell Carcinoma|Stage IV Renal Cell Cancer AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|DRUG: Cabozantinib S-malate|PROCEDURE: Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemia Preconditioning on Myocardial Injury in Patients Undergoing Heart Valve Surgery
Status: COMPLETED
Conditions: Heart Valve Diseases
Interventions: PROCEDURE: remote ischaemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy
Status: COMPLETED
Conditions: Cervical Myelopathy
Interventions: DRUG: Limaprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitric Oxide and Neuroprotection in Premature Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Prematurity|Bronchopulmonary Dysplasia|Intraventricular Hemorrhage|Periventricular Leukomalacia
Interventions: DRUG: inhaled nitric oxide|DRUG: oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Efficacy and Safety of Somatropin in Japanese Participants With PWS
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: BIOLOGICAL: somatropin - GH naïve pediatric cohort|BIOLOGICAL: somatropin - GH treated cohort|BIOLOGICAL: somatropin - adult cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biofeedback-based Motor Learning to Ameliorate Freezing of Gait
Status: UNKNOWN
Conditions: Gait|Parkinson Disease
Interventions: BEHAVIORAL: Biofeedback-based motor learning for PD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Surgical Treatment Versus Medical Management for Stroke Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: PROCEDURE: Minimally Invasive Surgery|OTHER: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 Trial
Status: RECRUITING
Conditions: Advanced Rare Malignant Solid Neoplasm|Rare Malignant Solid Neoplasm|Refractory Rare Malignant Solid Neoplasm
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|DRUG: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma Resuscitation With Low-Titer Group O Whole Blood or Products
Status: RECRUITING
Conditions: Wounds and Injuries|Shock, Hemorrhagic
Interventions: BIOLOGICAL: LTOWB|BIOLOGICAL: Components
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer, Familial Male|Radiotherapy; Complications|Chemotherapeutic Toxicity|Immune Checkpoint Inhibitor|CDK4/6 Inhibitor|Trastuzumab|Pertuzumab|PARP Inhibitor
Interventions: RADIATION: Chest wall / breast radiation with or without lymph node region radiation.(For all of the enrolled patients)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Nonpharmacologic Strategies for Pain With Inclusion, Respect, and Equity
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: CBT, Mindfulness, and Movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sublingually Generated S-nitroso-N-acetylcysteine on Systemic Blood Pressure.
Status: RECRUITING
Conditions: Hypertension|Cardiovascular Diseases
Interventions: DRUG: Mixture of Sodium Nitrite and N-acetylcysteine (NAC) crytals.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate RIST4721 in Hidradenitis Suppurativa (HS)
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: RIST4721|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Telemedicine System for Patients Carried for Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DEVICE: Monitoring evaluation by connected devices: Wristband activity tracker "Garmin Vivosmart® 3", "Fora® Scale 550", "Terraillon® Tensioscreen", Pulse oximeter "Nonin® 3230", thermometer "Fora® IR20b"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Photodynamic Diagnosis for Malignant Brain Glioma With 5-Aminolevulinic Acid（5-ALA）
Status: RECRUITING
Conditions: 5-aminolevulinic Acid|Malignant Glioma of Brain
Interventions: DRUG: 5 Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Effect of Bimosiamose on Ozone Induced Sputum Neutrophilia
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Bimosiamose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Heparin Types; Efficacy and Safety
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Hepalean Heparin|DRUG: PPC Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
Status: RECRUITING
Conditions: Cardiovascular Diseases|Lifestyle Factors
Interventions: BEHAVIORAL: Generic text messages|BEHAVIORAL: Interactive AI chatbot text messaging|BEHAVIORAL: Proactive pharmacist support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Diamyd® in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: rhGAD65 formulated in Alhydrogel® (Diamyd®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment of in-Stent Restenosis by Paclitaxel Coated PTCA Balloons (PACCOCATH - ISR II)
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: paclitaxel coated balloon catheter (device with drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tele-Drama Therapy for Community-Dwelling Older Adults With Constricted Life Space Mobility
Status: COMPLETED
Conditions: Constricted Life Space Mobility|Tele-drama Therapy
Interventions: BEHAVIORAL: Tele-drama therapy|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Understanding Dexmedetomidine in Neonates After Open Heart Surgery
Status: COMPLETED
Conditions: Tetrology of Fallot|Heart Ventricle|Hypoplastic Left Heart
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisolone vs. Ciclosporine in Severe Atopic Eczema
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Prednisolone|DRUG: Ciclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standardized Fecal Microbiota Transplantation for Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease|Ulcerative Colitis|Crohn's Disease
Interventions: PROCEDURE: FMT|DRUG: Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Electrical Activity of Preterm Infants on nCPAP With Binasal Prongs Versus RAM Cannula
Status: UNKNOWN
Conditions: Preterm Infants|Respiratory Distress Syndrome|CPAP|RAM Cannula|Diaphragm Electrical Activity
Interventions: OTHER: respiratory support- interface|OTHER: respiratory support- interface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Methylprednisolone and Rituximab in High Risk B-CLL
Status: COMPLETED
Conditions: Chronic B-Lymphocytic Leukemia
Interventions: DRUG: rituximab, methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Benefit, Safety, PK and PD Study of AT-007 in Pediatric Subjects With Classic Galactosemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Classic Galactosemia
Interventions: DRUG: AT-007|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Optimal Immunization Strategy of Hepatitis B Vaccine in Chronic Kidney Disease Population
Status: UNKNOWN
Conditions: Hepatitis B Vaccine
Interventions: BIOLOGICAL: 20 µg recombinant hepatitis B vaccine at months 0, 1, and 6|BIOLOGICAL: 20 µg recombinant hepatitis B vaccine at months 0, 1, 2,and 6|BIOLOGICAL: 60 µg recombinant hepatitis B vaccine at months 0, 1, 2,and 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PNF Techniques Versus Stabilization Exercises of Trapezius Muscle PNF Techniques Verus Stabilization Exercises of Trapezius Muscle
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: PNF stretching|OTHER: Stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A 12-Week Efficacy Study of Paracetamol 1000mg Sustained-release Tablets in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Paracetamol 1000 mg SR tablets|DRUG: Paracetamol 665 mg SR tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation in Preventing Postpartum Depression According to Watson
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy Related
Interventions: OTHER: THE EFFECT OF WATSON MODEL-BASED PSYCOEDUCATIONAL INTERVENTIONS ON PREVENTION OF POSTPARTITION DEPRESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Effects of Dopaminergic Medications on Dopamine Transporter Density in Subjects With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonian Syndrome
Interventions: DRUG: cabergoline|DRUG: carbidopa/levodopa|PROCEDURE: DATscan and SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Quadratus Lumborum Block Using Loss-of-resistance Versus Ultrasound-guided Technique
Status: UNKNOWN
Conditions: Lower Abdominal Surgery|Quadratus Lumborum Block
Interventions: PROCEDURE: Loss-of-resistance Quadratus lumborum block|PROCEDURE: Ultrasound-guided Quadratus lumborum block|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yellow Versus White Study
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: cataract surgery (Hoya AF-1 [UY] YA-60BB)|PROCEDURE: cataract surgery (Hoya AF-1 [UV] VA-60BB lens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COMFORT Study: A Crossover Study of NeoRecormon (Epoetin Beta) and Darbepoetin Alfa in Patients With Renal Anemia.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: darbepoetin alfa|DRUG: epoetin beta [NeoRecormon]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Cataract Surgery Alone and Cataract Surgery With iStent
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: iStent inject®|PROCEDURE: Phacoemulsification and intraocular lens implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AXIOS™ for Gallbladder Drainage as an Alternative to Percutaneous Drainage IDE
Status: COMPLETED
Conditions: Cholecystitis, Acute
Interventions: DEVICE: AXIOS(TM) Stent and Electrocautery Enhanced Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Neoadjuvant Therapy for Her-2 Positive Breast Cancer and the Prognosis by Detecting CTCs
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: Epirubicin|DRUG: Docetaxel|DRUG: Trastuzumab|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib in Treating Children With Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: gefitinib|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
Status: UNKNOWN
Conditions: Chills
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Single Doses of SBT115301 in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Safety
Interventions: BIOLOGICAL: SBT115301|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅰ Study to Evaluate the Safety and Tolerability of Using F520
Status: UNKNOWN
Conditions: Advanced Solid Tumor，Recurrent Solid Tumor，Lymphoma，Recurrent Lymphocyte Depleted Classical Hodgkin Lymphoma
Interventions: DRUG: Recombinant Humanized Anti-PD-1 Monoclonal Antibody Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Effects in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive|Multiple Sclerosis, Chronic Progressive|Multiple Sclerosis
Interventions: OTHER: Exercise Group 1|OTHER: Exercise Group 2|OTHER: Exercise Group 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Changes in Tumor Tissue and Serum Biomarkers Before and After Cetuximab Combined With Preoperative Radiotherapy in Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Locally Advanced Thoracic Middle-lower Segment Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: preoperative radiotherapy|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Left Ventricular Pacing Optimilization on Cardiac Perfusion, Contractile Force, and Clinical Performance in Patients With Ventricular Dysfunction and Heart Failure
Status: COMPLETED
Conditions: Left Ventricular Dysfunction|Heart Failure
Interventions: DEVICE: biventricular pacemaker with epicardial left ventricular lead|DEVICE: transvenous left ventricular lead placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dolutegravir in Pregnant HIV Mothers and Their Neonates
Status: COMPLETED
Conditions: HIV-1-infection|Pregnancy Related
Interventions: DRUG: Dolutegravir|DRUG: Standard of Care (EFV + 2 NRTI backbone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation on the Anxiety of Third Molar Extraction
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Spielberger State Anxiety Inventory (STAI-S),|BEHAVIORAL: Dental Fear Scale (DFS)|BEHAVIORAL: Modified Dental Anxiety Scale (MDAS)|BEHAVIORAL: Visual Analog Scale (VAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Pharmacokinetics, Pharmacodynamics of ASP1941 in Diabetes Mellitus Patients With Renal Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ASP1941
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Pilot Randomized Controlled Trial of Financial Incentives, Text Messaging, and Usual Care for Homeless Smokers
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Transdermal nicotine patch|BEHAVIORAL: In-person smoking cessation counseling|BEHAVIORAL: Contingent financial rewards for smoking abstinence|BEHAVIORAL: Text messages to support smoking abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GRT9906 Tablets Compared to Placebo in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Primary Fibromyalgia
Interventions: DRUG: GRT9906|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rescues On Reperfusion Damage In Cerebral Infarction by Nelonemdaz
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Neu2000KWL group|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SP-303T Applied to the Skin of Patients With Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success With Acyclovir
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Crofelemer
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hand Washing and WASH Educational Intervention on Under-five Diarrheal Diseases
Status: COMPLETED
Conditions: Diarrhea
Interventions: BEHAVIORAL: Hand washing with soap and Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: olopatadine hydrochloride ophthalmic solution 0.7%|DRUG: loratadine 10 mg|DRUG: Tears Naturale|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spanish Decision Tool for Ovarian Cancer Maintenance Therapy
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: OTHER: Shared Medical Decision Tool|BEHAVIORAL: Engaging Patients in Decision Making|BEHAVIORAL: Literacy Spanish Language
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pembrolizumab and Vorinostat in Treating Patients With Recurrent Squamous Cell Head and Neck Cancer or Salivary Gland Cancer That Is Metastatic and/or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Recurrent Nasopharynx Carcinoma|Recurrent Salivary Gland Carcinoma|Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary|Stage III Major Salivary Gland Carcinoma|Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage III Nasopharyngeal Carcinoma|Stage IV Nasopharyngeal Carcinoma|Stage IVA Major Salivary Gland Carcinoma|Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVB Major Salivary Gland Carcinoma|Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage IVC Major Salivary Gland Carcinoma|Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program"
Status: COMPLETED
Conditions: Dementia|Alzheimer's Disease|Dementia Prevention
Interventions: BEHAVIORAL: HALT-AD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Use of [123I] AV39 and SPECT Imaging as a Marker of Protein Disposition in Subjects With Alzheimer Disease Compared to Healthy Subjects
Status: COMPLETED
Conditions: Alzheimers Disease
Interventions: DRUG: [123I] AV 39
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of IV Diclofenac (DIC075V) for Pain After Abdominal or Pelvic Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Intravenous Diclofenac (DIC075V)|DRUG: Intravenous Ketorolac|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder.
Status: RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Toludesvenlafaxine Hydrochloride Sustained-release Tablet 80mg|DRUG: Toludesvenlafaxine Hydrochloride Sustained-release Tablet 160mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation for Cervical Cancer Survivors
Status: COMPLETED
Conditions: Cervical Cancer|Tobacco Use|Smoking Cessation
Interventions: BEHAVIORAL: Self-Help Materials|DRUG: Nicotine Patch|BEHAVIORAL: REDCap|PROCEDURE: Saliva Test|BEHAVIORAL: Telephone Counseling Sessions|DRUG: Nicotine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diagnostic Study to Predict the Risk of Developing Metastatic Cancer in Patients With Stage I or Stage II Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: GENETIC: comparative genomic hybridization|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|OTHER: immunohistochemistry staining method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: PET Study to Evaluate Brain Receptor Occupancy, Safety and Pharmacokinetics of ITI-1284 in Healthy Subjects
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: ITI-1284 10 mg|DRUG: ITI-1284 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumbar Thrust-mobilization Effects on Hip Strength and Anterior Knee Pain
Status: UNKNOWN
Conditions: Anterior Knee Pain Syndrome
Interventions: OTHER: Lumbar-thrust mobilization|OTHER: Sham thrust-mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Topiramate in Preventing the Transformation From Episodic Migraine to Chronic Daily Headache.
Status: COMPLETED
Conditions: Migraine|Headache|Classic Migraine|Common Migraine
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study Trial of Felbinac Trometamol Injection in China
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Felbinac Trometamol Injection|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Centralized Interventions on Lung Cancer Screening Adherence in Community Settings, ACCELL Trial
Status: ENROLLING_BY_INVITATION
Conditions: Lung Carcinoma
Interventions: OTHER: Electronic Health Record Review|OTHER: Interview|BEHAVIORAL: Patient Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Mobilization and Perceptive Rehabilitation on Patients With Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Perceptive Rehabilitation|OTHER: Mobilisation Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease
Status: RECRUITING
Conditions: Congenital Heart Disease|Neurodevelopmental Disorders|Electroencephalography|Near-Infrared Spectroscopy|Biomarkers
Interventions: DIAGNOSTIC_TEST: electroencephalography|DIAGNOSTIC_TEST: Near-Infrared Spectroscopy|DIAGNOSTIC_TEST: neuronal cell-free DNA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Evaluate Tolerability and Safety of FXFM244 and to Monitor Clinical Effect in Acne Vulgaris Patients
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Topical Minocycline Foam FXFM244
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Pembrolizumab, Followed by Pembrolizumab and Olaparib as Firstline Therapy in Her-2 Negative Gastric/GEJ Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophagogastric Adenocarcinoma
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib|DRUG: mFOLFOX-6|DRUG: CapOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liberal Transfusion Strategy in Elderly Patients
Status: RECRUITING
Conditions: Transfusion-dependent Anemia|Surgery|Anemia
Interventions: DRUG: red blood cell transfusion trigger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine to Increase Tumor Suppressor PAR-4 Levels in Oligometastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Recurrent
Interventions: DRUG: Hydroxychloroquine Sulfate 200Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endodontic Microsurgery With the Use of L-PRF Block
Status: RECRUITING
Conditions: Apical Periodontitis|Apical Periodontal Cyst
Interventions: PROCEDURE: Endodontic Microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Rectal Adenocarcinoma|Recurrent Rectal Carcinoma|Stage IV Rectal Cancer AJCC v7|Stage IVA Rectal Cancer AJCC v7|Stage IVB Rectal Cancer AJCC v7
Interventions: OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Trifluridine/Tipiracil Hydrochloride Combination Agent TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OPTImization of the Dose of tacroliMUS by Bayesian Prediction
Status: COMPLETED
Conditions: KIDNEY TRANSPLANTATION
Interventions: DRUG: Standard dosage of Tacrolimus|DRUG: Bayesian Prediction Tacrolimus dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of Persistent Atrial Fibrillation Ablation Using Ablation Index-guided Radiofrequency Catheter Ablation in Patients With Continuous Monitoring
Status: WITHDRAWN
Conditions: Persistent Atrial Fibrillation
Interventions: DEVICE: Ablation Index-guided ablation|DEVICE: High-power, short-duration ablation using QDOT Micro catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Decitabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Ways to Freeze the Nerve That Provides Thigh Sensation
Status: COMPLETED
Conditions: Meralgia Paresthetica
Interventions: DRUG: Nerve Injection- Nerve Stimulator|DRUG: Nerve Injection - Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment
Status: COMPLETED
Conditions: Substance Abuse|Substance Dependence|Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive Training + Work Therapy|BEHAVIORAL: Work Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMP as a Better Delivery System of Adenosine
Status: TERMINATED
Conditions: Ischemia
Interventions: DRUG: Adenosine|DRUG: Adenosine Mono Phosphate (AMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan Hydrochloride Liposome Injection (LY01610) For Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: LY01610( Irinotecan hydrochloride liposome injection )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual World-Based Cardiac Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Cardiac Event|Telemedicine|Cardiovascular Diseases
Interventions: OTHER: Virtual World-Based Cardiac Rehabilitation (VWCR)|OTHER: Center-Based Cardiac Rehabilitation (CBCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reinforced Staple Line on Leak Rate in Distal Pancreatectomy
Status: TERMINATED
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: Mesh reinforced staple line (SEAMGUARD)|DEVICE: Stapled without mesh reinforcement (PER-STRIPS DRY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Losartan Versus Atenolol for the Treatment of Marfan Syndrome
Status: COMPLETED
Conditions: Marfan Syndrome
Interventions: DRUG: Losartan|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glimepiride, Alogliptin and Alogliptin+Pioglitazone Combination
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Glimepiride|DRUG: Alogliptin 25Mg Tab|DRUG: Alogliptin-Pioglitazone 25 Mg-15 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ganglionated Plexi Ablation vs Renal Denervation in Patients Undergoing Pulmonary Vein Isolation
Status: COMPLETED
Conditions: Atrial Fibrillation|Hypertension
Interventions: PROCEDURE: PVI+renal denervation|PROCEDURE: PVI + GP ablation|DRUG: Optimal medial therapy (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Strains|Acute Lymphoblastic Leukemia|Sepsis
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of a New Paracetamol Oral Suspension 24mg/ml Compared to the Marketed Paracetamol Oral Suspension (Panadol Baby and Infant 24mg/ml) in Healthy Adult Subjects
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: New Paracetamol Oral Suspension (24 mg/ml)|DRUG: Panadol B&I Oral Suspension (24 mg/ml paracetamol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE