pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dose Ranging Study of GSK1265744 Plus Nucleoside Reverse Transcriptase Inhibitors for Induction of Human Immunodeficiency Virus-1 (HIV-1) Virologic Suppression Followed by Virologic Suppression Maintenance by GSK1265744 Plus Rilpivirine
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: GSK1265744 10 mg|DRUG: GSK1265744 30 mg|DRUG: GSK1265744 60 mg|DRUG: Efavirenz 600 mg|DRUG: Rilpivirine 25 mg|DRUG: Placebo|DRUG: Abacavir/Lamivudine (ABC/3TC) or Tenofovir/Emtricitabine (TDF/FTC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Movement System Impairment Based Classification Versus General Exercise for Chronic Non-specific Low Back Pain: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Treatment based on Movement System Impairment model|OTHER: General exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Combination of Mycophenolate Mofetil (MMF) and Tacrolimus (Tac) for Refractory Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: low dose combination of MMF and Tac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Muscle Strengthening on the Incidence of Psychomotor Disadaptation Syndrome in Elderly Persons
Status: NOT_YET_RECRUITING
Conditions: Psychomotor Disadaptation Syndrome|Post-fall Syndrome
Interventions: DIETARY_SUPPLEMENT: rehabilitation with muscle strengthening + Oral Nutritional Supplements|OTHER: rehabilitation with muscle strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bar and Ball Joint Overdentures Surface Roughness and Microbial Adherence
Status: COMPLETED
Conditions: Adhesiveness
Interventions: OTHER: Adherence mold and yeast and mesophyll aerobe|OTHER: Surface Roughness (Ra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Lactation on Insulin Sensitivity and Lipolysis in Women
Status: TERMINATED
Conditions: GDM|Lactation
Interventions: DIAGNOSTIC_TEST: Hyperinsulinemic-euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Paroxetine - Controlled Release in the Treatment of Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Paroxetine CR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SYV: A Mental Health Intervention to Improve HIV Outcomes in Tanzanian Youth
Status: RECRUITING
Conditions: HIV-1-infection|Mental Health Issue|Adherence, Medication
Interventions: BEHAVIORAL: SYV: Sauti ya Vijana (The Voice of Youth intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility of High Flow Nasal Cannula in CO Toxicity
Status: COMPLETED
Conditions: Carbon Monoxide Poisoning|Environmental Exposure
Interventions: DEVICE: Fisher&Paykel AIRVO™ 2 High Flow Nasal Cannula Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics of HRS4800 in Healthy Subjects
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: HRS4800|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of IDP-121 in Patients With Relapsed/Refractory Hematologic Malignancies
Status: RECRUITING
Conditions: Multiple Myeloma (MM)|Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|Double Hit Lymphoma|High Grade B-Cell Lymphoma, Not Otherwise Specified|Chronic Lymphocytic Leukemia (CLL)|Triple Hit Lymphoma
Interventions: DRUG: IDP-121
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patients With Familial Hypercholesterolemia or Severe-Hypercholesterolemia
Status: COMPLETED
Conditions: Lipid Metabolism, Inborn Errors|Hypercholesterolemia, Autosomal Dominant|Hyperlipidemias|Metabolic Diseases|Hyperlipoproteinemia Type II|Metabolism, Inborn Errors|Genetic Diseases, Inborn|Infant, Newborn, Diseases|Metabolic Disorder|Congenital Abnormalities|Hypercholesterolemia|Hyperlipoproteinemias|Dyslipidemias|Lipid Metabolism Disorders
Interventions: DRUG: Mipomersen Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico
Status: NOT_YET_RECRUITING
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Trauma Focused Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 and Anti-CD14 Treatment Trial
Status: TERMINATED
Conditions: Coronavirus Disease 2019 (COVID-19)|Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Interventions: BIOLOGICAL: anti-CD14|OTHER: Placebo|DRUG: remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Impacts of Theta Burst Stimulation Over Bilateral Posterior Superior Temporal Sulcus in Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4 Study to Evaluate Adrenal Function in Hypogonadal Men Treated With JATENZO® for 12 Months
Status: RECRUITING
Conditions: Hypogonadism
Interventions: DRUG: Jatenzo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteer
Interventions: DRUG: Generic empagliflozin 25 mg film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of PNX and Haemorrhagic Complications in Diagnostic Percutaneous Lung Biopsy Using the MIPP-Kit Device
Status: COMPLETED
Conditions: Complications in Diagnostic Percutaneous Lung Biopsy Procedures
Interventions: DEVICE: Percutaneous Lung Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fluorouracil and Low-Dose Suramin as Chemosensitization in Treating Patients With Metastatic Renal Cell (Kidney) Cancer
Status: COMPLETED
Conditions: Recurrent Renal Cell Carcinoma|Stage IV Renal Cell Cancer
Interventions: DRUG: Fluorouracil|OTHER: Pharmacological Study|DRUG: Suramin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.
Status: RECRUITING
Conditions: Hip Osteoarthritis|Hip Pain Chronic
Interventions: PROCEDURE: Conventional Radiofrequency (CRF group)|PROCEDURE: Intraarticular Infiltration ( Control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia
Status: COMPLETED
Conditions: Diabetes Mellitus and Hypercholesterolemia
Interventions: DRUG: Rosuvastatin+Ezetimibe|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women
Status: UNKNOWN
Conditions: Genitourinary Syndrome of Menopause
Interventions: OTHER: Intervention group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Treatment of Advanced Malignant Solid Tumor With Revottack and PD-1 Inhibitor
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Oncolytic Virus Injection（Revottack）+PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Evaluation of Attention to Faces After Orthognathic Surgery With Eye-tracking
Status: RECRUITING
Conditions: Dentofacial Deformities|Orthognathic Surgery|Social Perception|Eye Tracking
Interventions: OTHER: photographs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Benefits of Optiflow® Device for Preoxygenation Before Intubation in Acute Hypoxemic Respiratory Failure : The PREOXYFLOW Study
Status: COMPLETED
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DEVICE: PREOXYFLOW|PROCEDURE: STANDARD FACE MASK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telcagepant (MK-0974) Long-Term Safety Study in Adult Participants With Acute Migraine (MK-0974-012)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Telcagepant 300 mg soft gel capsules|DRUG: Telcagepant 280 mg tablets|DRUG: Rizatriptan 10 mg tablets|DRUG: Placebo to telcagepant capsules|DRUG: Placebo to telcagepant tablets|DRUG: Placebo to rizatriptan tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Result of TVT Performed at the Time of Prolapse Surgery or 3 Months After
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Urinary Stress Incontinence
Interventions: PROCEDURE: Vaginal Repair for prolapse, TVT procedure|PROCEDURE: TVT and Prolapse surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Ciclesonide and Formoterol Fumarate Inhaled Once Daily in Patients With Asthma (18 to 75 y) (BY9010/M1-506)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide/Formoterol Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of Itraconazole and Ciprofloxacin on Single-Dose PK of Pracinostat in Healthy Nonsmoking Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Non-smokers
Interventions: DRUG: Pracinostat|DRUG: Itraconazole|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nurse-led Antimicrobial Stewardship Intervention to Increase Antibiotic Appropriateness in Residential Aged Care Facilities
Status: UNKNOWN
Conditions: Antimicrobial Stewardship|Urinary Tract Infections|Respiratory Tract Infections|Skin and Soft Tissue Infections
Interventions: BEHAVIORAL: Antimicrobial stewardship
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety & Effectiveness of Vascular Sealant System
Status: TERMINATED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Gelfoam/Thrombin|DEVICE: VascuSeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Escalation Study to Determine Bioavailability of a Single Oral Dose of Decitabine in Patients With Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: decitabine|DRUG: decitabine|DRUG: decitabine|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Xanomeline and Trospium Chloride Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Progressive Relaxation Exercises on Pain and Bowel Movements in Patients Undergoing Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Pain, Postoperative
Interventions: OTHER: progressive relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Intraocular Lowering Effect of Delivery of Travoprost Evolute® in Subjects With Elevated Intraocular Pressure
Status: COMPLETED
Conditions: Elevated Intraocular Pressure (IOP)
Interventions: COMBINATION_PRODUCT: Travoprost Evolute® (Travoprost Punctal Plug Delivery System), 166 ug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Safety, Tolerability, Immunogenicity and Pharmacokinetics of Single-Dose of PF-06823859 in Japanese Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-06823859|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Balanced Hypocaloric Diet Associated With Supplementation of Eggplant Meal in the Remission of Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Obesity|Obesity, Abdominal
Interventions: DIETARY_SUPPLEMENT: eggplant meal|OTHER: cassava meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spectroscopic MRI Guided Proton Therapy in Assessing Metabolic Change in Pediatric Patients With Brain Tumors
Status: RECRUITING
Conditions: Malignant Brain Glioma
Interventions: PROCEDURE: Magnetic Resonance Spectroscopic Imaging|DEVICE: Proton Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Constraint Induced Movement Therapy (CIMT)- Neuroimaging Predictors of Positive Response to Constraint
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: Casting & CIMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease
Status: RECRUITING
Conditions: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)
Interventions: DRUG: Satralizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Better Choice for Patients Undergoing Endovascular Coil Embolization
Status: COMPLETED
Conditions: Intracranial Aneurysms
Interventions: DRUG: sevoflurane and 0.5 μg/kg dexmedetomidine|DRUG: sevoflurane and 1 μg/kg dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients
Status: COMPLETED
Conditions: Systemic Sclerosis|Ulcers
Interventions: DRUG: macitentan 3mg|DRUG: macitentan 10mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The PROMISE Study: Duavee in Women With DCIS
Status: RECRUITING
Conditions: Ductal Breast Carcinoma In Situ|Postmenopausal
Interventions: DRUG: Conjugated Estrogens/Bazedoxifene|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Placebo|PROCEDURE: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Living Green and Healthy for Teens
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Lifestyle|Adolescent Behavior
Interventions: BEHAVIORAL: Aim2Be smartphone app system|BEHAVIORAL: BnLt smartphone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Extension Study to Evaluate the Biodegradation of the Brimonidine Tartrate Posterior Segment Drug Delivery System
Status: COMPLETED
Conditions: Patients Who Participated in an Intravitreal Brimo PS DDS® Study
Interventions: DRUG: Brimo PS DDS®|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Non-Interventional Post Marketing Surveillance Study of Neovasculgen® in Patients With Chronic Lower Limb Ischemia
Status: COMPLETED
Conditions: Lower Limb Ischemia
Interventions: DRUG: Neovasculgen®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Locomotor Training in Individuals With Incomplete Spinal Cord Injury. A Pilot Study
Status: UNKNOWN
Conditions: Incomplete Spinal Cord Injury
Interventions: OTHER: Conventional gait training|OTHER: End-effector based gait training|OTHER: combined training (conventional and end-effector-based)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Of PF-00547659 In Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: 75mg SHP647 (PF-00547659)|DRUG: 225mg SHP647 (PF-00547659)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment to Improve TBM Outcomes in Children
Status: COMPLETED
Conditions: Tuberculosis, Meningeal
Interventions: DRUG: High-dose: RIF, INH, PZA, EMB|DRUG: High dose: RIF, INH, PZA, LEVO|DRUG: Standard of care: RIF, INH, PZA, EMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs
Status: UNKNOWN
Conditions: Shivering
Interventions: DRUG: Pethidine|DRUG: Acetaminophen|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: No-Touch Versus Conventional Saphenous Vein Harvesting Technique
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: No-Touch vein harvesting technique|PROCEDURE: Conventional vein harvesting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine|DRUG: Duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer|Peripheral Neuropathy|Cardiac Toxicities|Hepatic Toxicity|Cognitive Impairment
Interventions: DRUG: Silymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Obicetrapib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteopathic Techiniques on Intraocular Pressure
Status: COMPLETED
Conditions: Intraocular Pressure|Osteopathic Manipulative Treatment
Interventions: OTHER: Upper cervical manipulation|OTHER: Sphenopalatine ganglion manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Learning Brushing Using Game Elements in Mobile Phones Apps
Status: UNKNOWN
Conditions: Oral Hygiene|Dental Plaque|Children, Only|Dental Devices, Home Care|Motivation|Learning
Interventions: BEHAVIORAL: Manual toothbrush Curaprox 5460 ultra soft|BEHAVIORAL: Electric toothbrush Play Smart Brush N°1|BEHAVIORAL: Electric toothbrush Play Smart Brush N°2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Irbesartan 150/12.5 mg and 300/25 mg in Patients With Mild Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: IRBESARTAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab in Participants With Squamous Cell Carcinoma of the Head & Neck (SCCHN) - Patient Reported Outcomes (PRO)
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: Nivolumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: neratinib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BEFORE Decision Aid Implementation Study
Status: UNKNOWN
Conditions: Decision Support Techniques|Breast Neoplasm Female|Young Adult|Evaluation Studies
Interventions: BEHAVIORAL: BEFORE decision aid|BEHAVIORAL: BEFORE decision aid|BEHAVIORAL: BEFORE decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Doxorubicin Plus External-Beam Radiation Therapy in Treating Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Doxorubicin Hydrochloride|RADIATION: Radiation Therapy (RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Arthroscopic Labral Excision or Repair Trial (ALERT)
Status: UNKNOWN
Conditions: Acetabular Labrum Tear
Interventions: PROCEDURE: Arthroscopic acetabular labral repair|PROCEDURE: Arthroscopic acetabular labral resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas
Status: COMPLETED
Conditions: Neurofibromatosis
Interventions: DRUG: Gleevec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatase Inhibitor-Associated Musculoskeletal Symptoms in Non-Metastatic, Post Menopausal Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: History and Physical Exam|OTHER: Grip Strength Measurement|BEHAVIORAL: Surveys|OTHER: Blood Collection|PROCEDURE: Ultrasound of Hand/Wrist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Versus Niacin in Patients With Coronary Artery Disease (CAD) and Low High-Density Lipoproteins (HDL)
Status: COMPLETED
Conditions: Coronary Disease|Hypolipoproteinemia
Interventions: BEHAVIORAL: physical exercise|DRUG: niaspan (extended-release niacin)|DRUG: niacin|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing PrEP Use in High-Risk Social Networks of African-American MSM in Underserved Low-Risk Cities
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus
Interventions: BEHAVIORAL: Social Network|BEHAVIORAL: Brief HIV Prevention Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: DW Evaluation of Lotrafilcon B Lenses in a Modified Design
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B sphere modified design contact lenses|DEVICE: Lotrafilcon B sphere contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: DTG/3TC|DRUG: Cabotegravir (CAB) LA|DRUG: Rilpivirine (RPV) LA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Lymphoproliferative Disorder|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Impact of Food Carbohydrate and Insulin Dose Computing by on Smart Phone on Glucose Control in Patients With Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Automated carbohydrate and meal insulin dose computing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LILRB4 STAR-T Cell Therapy for Monocytic Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myelogenous Leukemia|Chronic Myelomonocytic Leukemia
Interventions: BIOLOGICAL: LILRB4 STAR-T cells injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Parallel Crossover Study Demonstrating Subject Wearability and Usability of the I-Port Injection Port
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: I-Port(TM) Injection Port
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intratympanic N-Acetylcysteine for Prevention of Cisplatin-induced Ototoxicity.
Status: RECRUITING
Conditions: Ototoxic Hearing Loss
Interventions: DRUG: N-Acetyl Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Peg-Granulocyte-Colony Stimulating Factor (GCSF) for Coronary Collateral Growth in Coronary Artery Disease Patients
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BIOLOGICAL: pegfilgrastim|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of fESWT in the Treatment of CTS
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: focused extracorporeal shock wave therapy|OTHER: sham focused extracorporeal shock wave therapy|OTHER: night splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety Of PF-06342674 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|BIOLOGICAL: PF-06342674 Dose A|BIOLOGICAL: PF-06342674 Dose B|BIOLOGICAL: PF-06342674 Dose C|BIOLOGICAL: PF-06342674 Dose D|BIOLOGICAL: PF-06342674 Dose E|BIOLOGICAL: PF-06342674 Dose F|BIOLOGICAL: PF-06342674 Dose G|BIOLOGICAL: PF-06342674 Dose H|BIOLOGICAL: PF-06342674 Dose I|BIOLOGICAL: PF-06342674 Dose J
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of PSSE on Plantar Pressure Distribution and Balance in Scoliosis
Status: UNKNOWN
Conditions: Scoliosis; Adolescence|Physiotherapy|Exercise|Balance
Interventions: OTHER: PSSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial on the Recurrence Free Survival Rate of Type I AIP With High-risk of Recurrence
Status: RECRUITING
Conditions: Type 1 AIP
Interventions: DRUG: Glucocorticoids|DRUG: Glucocorticoids+MMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of Tripterygium (TW) Versus AZA in the Maintenance Therapy for Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Tripterygium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Single Session of Aerobic Exercise on Acute Pain and Function in Patients After Total Knee Replacement
Status: UNKNOWN
Conditions: Total Knee Replacement
Interventions: PROCEDURE: aerobic effort|OTHER: passive pedaling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)
Status: COMPLETED
Conditions: Graft Versus Host Disease
Interventions: DRUG: RGI-2001|DRUG: Calcineurin Inhibitors|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Conditioning Regimen|PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Methotrexate|DRUG: Mofetil Mycophenolate|DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing 0.5mg of Ranibizumab and Higher Doses in the Treatment of Clinically Significant Diabetic Macular Edema
Status: COMPLETED
Conditions: Clinically Significant Diabetic Macular Edema
Interventions: DRUG: ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune Persistence After Inoculated With One-dose Freeze-Dried Live Attenuated Varicella Vaccine in Children Vaccine in Children
Status: UNKNOWN
Conditions: Chickenpox
Interventions: BIOLOGICAL: Live Attenuated Varicella Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology
Status: TERMINATED
Conditions: Rectal Cancer|Rectal Adenocarcinoma
Interventions: DEVICE: Probe-based confocal laser endomicroscopy|PROCEDURE: Rectoscopy|PROCEDURE: EUS|PROCEDURE: Biopsy and resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimizing Sleep Health in Nurses
Status: RECRUITING
Conditions: Circadian Rhythm Sleep-Wake Disorders, Shift Work Type|Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: CBTI|BEHAVIORAL: MRTI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2)
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Neoaddjuvant Stereotactic Radiotherapy with Simultaneous Integrated Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: PEX168 or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Magnitude and Prediction of Response to Omalizumab and Mepolizumab in Adult Severe Asthma.
Status: RECRUITING
Conditions: Severe Asthma
Interventions: DRUG: Randomisation to omalizumab|DRUG: Randomisation to mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Thalidomide, Prednisone, and Bevacizumab to Treat Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Thalidomide|DRUG: Prednisone|BIOLOGICAL: bevacizumab|GENETIC: polymorphism analysis|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Gefitinib in Squamous NSCLC Patients Who Failed First-Line Chemotherapy
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Bronchus
Interventions: DRUG: Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor Combined With Radiotherapy for Elderly ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: PD-1 inhibitor 200mg per three to four weeks, for one year
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Bolivian L Braziliensis Mucosal Leishmaniasis With Inhaled Pentamidine Plus Oral Miltefosine
Status: NOT_YET_RECRUITING
Conditions: Mucosal Leishmaniasis
Interventions: DRUG: Miltefosine Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Combined With TGP as First-line Therapy in Patients With Recurrent/Metastatic Nasopharyngeal Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma by AJCC V8 Stage
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Reconstitution After Autologous Hematopoietic Stem Cell Transpl for High-Risk Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Small Intestine Cancer
Interventions: BIOLOGICAL: Streptococcus pneumoniae|OTHER: laboratory correlative studies|OTHER: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacist Role in Thyroid Disorders
Status: COMPLETED
Conditions: Hypothyroidism|Hyperthyroidism|Thyroid Diseases
Interventions: BEHAVIORAL: Clinical Pharmacist Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing Feasibility of Prolonged Repetitive Near Infrared Light Stimulation in Early to Mid-Stage Dementia
Status: UNKNOWN
Conditions: Mild to Moderate Dementia
Interventions: DEVICE: Helmet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technological Balance and Gait Rehabilitation in Patients With Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis|Balance|Cognitive Impairment
Interventions: DEVICE: Technological rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: etafilcon A investigational cosmetic lens 1|DEVICE: etafilcon A investigational cosmetic lens 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of ILIADE : Exploring Health Literacy Within Patients Hospitalized for Acute Cardiovascular Events
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Chronic Heart Failure
Interventions: OTHER: Exploring health literacy levels and patients' informal needs or individual relationship between caregivers and patients.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transcranial Direct Current Stimulation (tDCS) and Hallucinations in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Auditory Hallucinations
Interventions: PROCEDURE: active tDCS|PROCEDURE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of OSI-7904L as Treatment in Patients With Head and Neck Cancer Who Have Failed First-Line Therapy
Status: COMPLETED
Conditions: Locally Recurrent or Metastatic Cancer of the Head and Neck|Must Have Failed First-Line Therapy
Interventions: DRUG: OSI 7904L
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Systemic Therapy and Chemoradiation in Advanced Localised Pancreatic Cancer - 2
Status: COMPLETED
Conditions: Pancreatic Neoplasms (Locally Advanced Non-metastatic)
Interventions: DRUG: nab-paclitaxel|RADIATION: 60Gy in 30#|RADIATION: 50.4Gy in 28#|DRUG: Nelfinavir|DRUG: Capecitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Non Invasive Vagal Stimulation to Prevent Chemotherapy-induced Nausea
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: non invasive auricular vagal stimulation|DRUG: usual medical treatment|DEVICE: sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: APR-548 in Combination With Azacitidine for the Treatment of TP53 Myelodysplastic Syndromes (MDS)
Status: TERMINATED
Conditions: MDS|Myelodysplastic Syndromes
Interventions: DRUG: APR-548 + Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irinotecan, TAS-102 Plus Bevacizumab as a Third-Line or Beyond Therapy in mCRC Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rate Control in Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DRUG: Carvedilol|DRUG: Metoprolol tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Reusable Mask Design With Superior Filtration and Fit
Status: COMPLETED
Conditions: Covid19|Tuberculosis|Respiratory Viral Infection
Interventions: DEVICE: N95 mask|DEVICE: Nordell single E-100 layer mask|DEVICE: Nordell double E-100 layer mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Fortified Complementary Foods on Vitamin A Status and Body Pool Size in Ghanaian Infants.
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Vitamin A supplements|DIETARY_SUPPLEMENT: Sprinkles without Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: US vs. LASER on Post Cesarean Anterior Cutaneous Branches of Iliohypogastric Neurotmesis
Status: UNKNOWN
Conditions: Neurotmesis
Interventions: DEVICE: low intensity pulsed ultrasound plus static abdominal and pelvic floor exercises.|DEVICE: low level LASER plus static abdominal and pelvic floor exercises.|OTHER: static abdominal and pelvic floor exercises only.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Social Media Personalized Normative Feedback Intervention for Heavy Drinking College Students
Status: RECRUITING
Conditions: Alcohol Consumption
Interventions: BEHAVIORAL: Alcohol personalized normative feedback (APNF)|BEHAVIORAL: Social media personalized normative feedback (SMPNF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Obese Taste Bud Study
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: taste bud biopsy|DIAGNOSTIC_TEST: oral glucose tolerance test|DIAGNOSTIC_TEST: Taste sensitivity|DIAGNOSTIC_TEST: olfactory function|DIAGNOSTIC_TEST: taste bud density|DIAGNOSTIC_TEST: anthropometry|OTHER: biospecimen collection|OTHER: questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of a Walking Program on Balance, Falls and Well Being in Individuals Residing in Long-term Care
Status: COMPLETED
Conditions: Accidental Falls|Muscle Weakness|Gait, Unsteady|Depression|Behavior
Interventions: BEHAVIORAL: Interpersonal Interaction|BEHAVIORAL: Walking Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect Observation Study of COX-2 Inhibitor to Treat Primary Hypertrophic Osteoarthropathy
Status: UNKNOWN
Conditions: Primary Hypertrophic Osteoarthropathy
Interventions: DRUG: COX-2 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of KTN3379 in Adult Subjects With Advanced Tumors
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: KTN3379
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sorafenib on Portal Pressure
Status: COMPLETED
Conditions: Clinically Significant Portal Hypertension
Interventions: DRUG: Placebo|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma|Marginal Zone Lymphoma|MZL
Interventions: DRUG: Venetoclax|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT