pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Contribution to the Analysis of the Phenotypic Heterogeneity in Crack/Cocaine Addiction : a Case Control Study
Status: UNKNOWN
Conditions: Dependence, Cocaine
Interventions: GENETIC: Collect 10 ml of Saliva for DNA extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse
Status: COMPLETED
Conditions: The Retention of Iodine in Saliva Over the Time|The Comparison of Iodine in Saliva Between Gargle and Swab
Interventions: OTHER: Iodine gargle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telehealth After Stroke Care: Integrated Multidisciplinary Access to Post-stroke Care
Status: COMPLETED
Conditions: Stroke|Health Care Acceptability|Hypertension
Interventions: OTHER: Usual care|OTHER: TASC intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Electrical Performance Evaluation of INVICTA Leads Models Equipped With DF4 Connector
Status: UNKNOWN
Conditions: Ventricular Arrythmia|Lead|ICD|Heart Failure
Interventions: DEVICE: Implant of the INVICTA lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19)
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: RPH-104 80 mg|DRUG: Olokizumab 64 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HLRCC|Sporadic Papillary Renal Cell Cancer
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Undisplaced Femoral Neck Fractures 2 Hansson Pins or 3 Pins Interlocked in Plate (Pinloc) Using RSA
Status: COMPLETED
Conditions: Hip Fractures|Femoral Neck Fractures
Interventions: DEVICE: Pinloc|DEVICE: 2 Hansson pins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact de la Marge de résection Sur la Survie à Long Terme et le Taux de récidive Des Patients Atteints de Cancers Colorectaux opérés au CHUS Entre 2006 et 2016 Pour Des métastases hépatiques
Status: COMPLETED
Conditions: Colorectal Cancer Stage IV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Internet-delivered Emotion Regulation Individual Therapy for Adolescents With NSSI - An Open Pilot Study
Status: COMPLETED
Conditions: Nonsuicidal Self-Injury
Interventions: BEHAVIORAL: Internet-delivered Emotion Regulation Individual Therapy for Adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Combined With Mindfulness: ACUMIND
Status: TERMINATED
Conditions: Chronic Pain
Interventions: OTHER: Music recording|OTHER: Mindfulness recording
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial to Evaluate the Safety and Pharmacokinetic
Status: UNKNOWN
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: HUG186-B and HUG186-D|DRUG: HUG186
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Venetoclax Combined With Azacytiside in the Treatment of Myelodysplastic/Myeloproliferative Neoplasms in Adults
Status: UNKNOWN
Conditions: Myelodysplastic/Myeloproliferative Neoplasms|Adult
Interventions: DRUG: venetoclax combined with azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Duet 2.0 Starting the Conversation: A New Intervention Model to Stimulate Language Growth in Underserved Populations
Status: UNKNOWN
Conditions: Language Development|Language, Child|Early Intervention
Interventions: BEHAVIORAL: Duet Language Intervention Modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alcohol and Cigarette Craving During Oxytocin Treatment
Status: COMPLETED
Conditions: Alcohol Use Disorder|Smoking
Interventions: DRUG: Oxytocin nasal spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Initial Assessment of the Effect of the Addition of Disulfiram (Antabuse) to Standard Chemotherapy in Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: chemotherapy +/- disulfiram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Menstrual Cycle and Oral Contraceptive Pill Phase on Aspects of Exercise Physiology
Status: RECRUITING
Conditions: Menstrual Cycle|Oral Contraceptives
Interventions: OTHER: Exercise and blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
Status: RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Resmetirom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Pharmacokinetic Action of Amantadine and Ribavirin in Chronic Hepatitis C. CINAM
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ribavirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases
Status: RECRUITING
Conditions: Rheumatic Diseases|COVID-19 Vaccine|COVID-19|SLE
Interventions: BEHAVIORAL: COVID-19 vaccine and booster training, and importance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina
Status: UNKNOWN
Conditions: Coronary Heart Disease|Unstable Angina
Interventions: DRUG: Xuesaitong soft capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home
Status: COMPLETED
Conditions: Cognitive Decline Prevention in Robust Older Adults|Cognitive Decline Prevention in Pre-frail Older Adults|Physical Decline Prevention in Robust Older Adults|Physical Decline Prevention in Pre-frail Older Adults
Interventions: BEHAVIORAL: SFL training|BEHAVIORAL: Active controlled training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Dietary Fibre in Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Fibre 1 (combined fibres)|DIETARY_SUPPLEMENT: Fibre 2 (natural fibres)|DIETARY_SUPPLEMENT: Dietary Supplement: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|High Blood Sugar
Interventions: DRUG: AZD1656
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Oxygen Application With Double Nasal Cannula on Respiratory Complications
Status: NOT_YET_RECRUITING
Conditions: Gastric Disease|Gastric Distress
Interventions: DRUG: OXYGEN THERAPY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of IPV Priming and Antibody Decay
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Bivalent oral poliovirus vaccine (bOPV) at 6,10 and 14 weeks of age|BIOLOGICAL: Inactivated poliovirus vaccine (IPV) at 14 weeks and 18 months of age|BIOLOGICAL: Inactivated poliovirus vaccine (IPV) at 14 weeks, 18 weeks and 18 months of age|BIOLOGICAL: Inactivated poliovirus vaccine (IPV) at 14 weeks and 9 months of age|BIOLOGICAL: Inactivated poliovirus vaccine (IPV) at 6 weeks and 9 months of age|BIOLOGICAL: Inactivated poliovirus vaccine (IPV) at 6 and 14 weeks of age
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Adult Acute Megakaryoblastic Leukemia|Adult Acute Monoblastic Leukemia|Adult Acute Monocytic Leukemia|Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With Maturation|Adult Acute Myeloid Leukemia With Minimal Differentiation|Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11|Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1|Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL|Adult Acute Myeloid Leukemia Without Maturation|Adult Acute Myelomonocytic Leukemia|Adult Erythroleukemia|Adult Pure Erythroid Leukemia|Alkylating Agent-Related Acute Myeloid Leukemia|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts|Recurrent Adult Acute Myeloid Leukemia|Secondary Myelodysplastic Syndrome
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Azacitidine|DRUG: Busulfan|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Methotrexate|OTHER: Pharmacological Study|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Photodynamic Therapy in Patients With Prostate Cancer Following Radiation Therapy
Status: COMPLETED
Conditions: Recurrent or Persistent Localized Carcinoma of the Prostate Following Radiation Therapy Failure
Interventions: DRUG: WST09
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Pirfenidone in Progressive Chronic Hypersensitivity Pneumonitis
Status: COMPLETED
Conditions: Hypersensitivity Pneumonitis
Interventions: DRUG: Oral pirfenidone|DRUG: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Self-management Program After Traumatic Injury
Status: RECRUITING
Conditions: Trauma Injury|Trauma, Multiple|Polytrauma
Interventions: BEHAVIORAL: self-management support program|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Choroidal Neovascularization|Degenerative Myopia|Pathological Myopia
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D3 Therapy on Vitamin D Status in Pregnant Women With Vitamin D Deficient and Insufficient
Status: ACTIVE_NOT_RECRUITING
Conditions: Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Transtec (R) PRO (buprenorphine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation Strategies Following Oesophagogastric and Hepatopancreaticobiliary Cancer
Status: RECRUITING
Conditions: Oesophageal Cancer|Gastric Cancer|Liver Cancer|Pancreatic Cancer
Interventions: OTHER: RESTORE II Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Diabetic Foot Education by Viewing Personal Plantar Pressures
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Neuropathies|Foot Complications
Interventions: BEHAVIORAL: Enhanced foot care education|BEHAVIORAL: Standard Foot Care Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)
Status: NOT_YET_RECRUITING
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: Nusinersen|DEVICE: ThecaFlex DRx System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H5N8 Mix and Match With or Without AS03 or MF59 in Healthy Adults
Status: COMPLETED
Conditions: Avian Influenza|Influenza
Interventions: DRUG: AS03|DRUG: MF59 adjuvant|BIOLOGICAL: Monovalent Influenza A/H5N8 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Urinary Vs Recombinant FSH in Oocyte Donors Based on Receptor N680S FSH Gene Polymorphism (Genodon Trial)
Status: UNKNOWN
Conditions: Reproductive Techniques, Assisted
Interventions: DRUG: Urinary follicle-stimulating hormone|DRUG: Recombinant follicle-stimulating hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPM 927 (400mg/Day and 600mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: SPM 927
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients
Status: UNKNOWN
Conditions: Pneumonia|Thrombocytopenia
Interventions: DRUG: recombinant human thrombopoietin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement
Status: RECRUITING
Conditions: Postoperative Atrial Fibrillation
Interventions: DRUG: Atorvastatin 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human (Autologous) Oral Mucosal Cell Sheet Transplantation After ESD in Patients With Superficial Esophageal Cancer
Status: COMPLETED
Conditions: Superficial Esophageal Cancer
Interventions: DEVICE: CLS2702C/CLS2702D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.
Status: RECRUITING
Conditions: ACL Injury|Knee Osteoarthritis|Knee Injuries
Interventions: BIOLOGICAL: Platelet-rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336 in Healthy, Male Subjects
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: RTI-336 (CTDP 31862)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pirtobrutinib and Venetoclax With MRD Detection for Previously Untreated Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Pirtobrutinib|PROCEDURE: Positron Emission Tomography|DRUG: Venetoclax|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increased Frequency of AlloStim(TM) Dosing in Combination With Cryoablation in Metastatic Breast Cancer Patients
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: AlloStim|PROCEDURE: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload
Status: COMPLETED
Conditions: Transfusional Iron Overload|Beta-thalassemia
Interventions: DRUG: SPD602 (FBS0701, SSP-004184)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Combination of Binimetinib and Encorafenib in Adolescent Patients With Unresectable or Metastatic BRAF V600-mutant Melanoma
Status: TERMINATED
Conditions: Melanoma
Interventions: DRUG: binimetinib|DRUG: encorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ADI-PEG 20 Versus Placebo in Subjects With High Arginine Level and Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Advanced Hepatocellular Carcinoma
Interventions: DRUG: ADI-PEG20|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oncolytic Virus Injection (RT-01) in Combination With PD-1 Inhibitor in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Oncolytic Virus Injection(RT-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effectiveness of Two Post-fasciectomy Rehabilitation Protocols in Patients With Dupuytren's Disease
Status: UNKNOWN
Conditions: Dupuytren Contracture
Interventions: OTHER: Brief protocol|OTHER: Intense protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial to Evaluate the Efficacy and Safety of HM61713 as the 1st-line NSCLC Anticancer Therapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: HM61713
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on Symptoms and Intestinal Flora in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Control placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Therapeutic Exploratory Study of CWP-0403
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: CWP-0403 100mg|DRUG: placebo|DRUG: CWP-0403 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Confocal Laser Endomicroscopic (CLE) Features and Colorectal Mucosal Microbiome
Status: COMPLETED
Conditions: Colorectal Neoplasia|Colorectal Inflammation|Hyperplasia|Mucosal Microbiome
Interventions: OTHER: the mucosal microbiome in the biopsy specimen was analysed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Efficacy of Dexamethasone in Different Routes of Administration in Transverse Abdominis Plane Block
Status: COMPLETED
Conditions: INFERTILITY
Interventions: DRUG: Perineural Dexamethasone acetate|DRUG: Intravenous dexamethasone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA
Status: TERMINATED
Conditions: Surgical Wound|Bilateral Total Knee Arthroplasty|Wounds and Injuries|Joint Diseases|Musculoskeletal Diseases|Edema Leg|Joint Pain|Arthritis Knee
Interventions: DEVICE: Closed Incision Negative Pressure Therapy (ciNPT)|DEVICE: Standard Silver-containing Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence|Substance Abuse|Methamphetamine Abuse
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recurrence Post-transplant Observational Study in Focal Segmental Glomerulosclerosis and Minimal Change Disease
Status: RECRUITING
Conditions: Focal Segmental Glomerulosclerosis|Minimal Change Disease|FSGS|MCD
Interventions: OTHER: Biospecimen collection|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Malaria Vaccine Safety and Immunogenicity Study in Healthy Adults
Status: COMPLETED
Conditions: Malaria Vaccine
Interventions: BIOLOGICAL: RTS,S/AS01B Fractional dose|BIOLOGICAL: Double RTS,S/AS01E Fractional dose|BIOLOGICAL: RTS,S/AS01E Standard dose|BIOLOGICAL: RTS,S/AS01E + DHA-PIP+PQ Standard dose|BIOLOGICAL: RTS,S/AS01E Fractional dose|BIOLOGICAL: RTS,S/AS01E + DHA-PIP+PQ Fractional dose|BIOLOGICAL: RTS,S/AS01E + DHA-PIP+PQ Fractional two-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Knee Arthroplasty Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthroplasty|Replacement|Knee
Interventions: DEVICE: CORI Robotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS Improves Functions in Spinocerebellar Ataxia
Status: RECRUITING
Conditions: Transcranial Magnetic Stimulation|Spinocerebellar Ataxias
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Long-Term Use of Perforomist® (Formoterol Fumarate)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Perforomist-Placebo|DRUG: Perforomist, nebulization, COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Migration and Functional Outcome of DELTA Xtend Reverse Shoulder Lateralized Glenosphere Line Extension System
Status: RECRUITING
Conditions: Rotator Cuff Arthropathy or Degeneration of the Glenohumeral Joint With Severe Posterior Wear
Interventions: PROCEDURE: Reverse shoulder arthroplsaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan
Status: UNKNOWN
Conditions: Brain and Central Nervous System Tumors|Recurrent Glioblastoma Multiforme
Interventions: DRUG: CT-322|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tamsulosin and Solifenacin in Treatment of Ureteral Stent Symptoms
Status: COMPLETED
Conditions: Relieve of Ureteral Stent Symptoms
Interventions: DRUG: Tamsulosin|DRUG: Solifenacin|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Creatine and Caffeine on Muscle Performance
Status: UNKNOWN
Conditions: Performance Enhancing Product Use
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate|DIETARY_SUPPLEMENT: Creatine Monohydrate and Caffeine|DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2b Dose-ranging Trial to Evaluate Delgocitinib Cream 1, 3, 8, and 20 mg/g Compared to Delgocitinib Cream Vehicle Over a 16-week Treatment Period in Adult Subjects With Chronic Hand Eczema
Status: COMPLETED
Conditions: Chronic Hand Eczema
Interventions: DRUG: Delgocitinib cream|DRUG: Delgocitinib cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROSA: Prolactin, Sex Hormones, Growth and Metabolic Biomarkers in Children and Adolescents on Antipsychotics
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperprolactinemia|Puberty Disorders|Metabolic Syndrome|Growth Disorders|Antipsychotics and Neuroleptics Toxicity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Application of Fibroblast Activation Protein PET/MRI for Diagnosis and Staging in Malignant Tumors
Status: UNKNOWN
Conditions: Malignant Neoplasm
Interventions: DRUG: 68Ga-DOTA-FAPI|DEVICE: PET/MR|DEVICE: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Panblok H7 Vaccine Adjuvanted With AS03 or MF59
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: 3.75 ug Panblok H7|BIOLOGICAL: 7.5 ug Panblok H7|BIOLOGICAL: 15 ug Panblok H7|BIOLOGICAL: MF59|BIOLOGICAL: AS03
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Optimization of the Healing Process of the Uterine Scar Tissue After Re-cesarean Section
Status: COMPLETED
Conditions: Scar; Previous Cesarean Section|Complications; Cesarean Section, Wound, Dehiscence
Interventions: PROCEDURE: resection of uterine scar tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase IIIB Dose Comparison Study of Subcutaneous Hydration With and Without Human Recombinant Hyaluronidase (HYLENEX) in Volunteer Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Hylenex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast
Status: COMPLETED
Conditions: Mammographically Dense Breast
Interventions: DRUG: Afimoxifene|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway
Status: TERMINATED
Conditions: Diabetes|Diabetes Complications|Neuropathy|Peripheral Neuropathy|Diabetic Foot Ulcer
Interventions: DEVICE: SurroSense Rx System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Imaging of T-Cell Activation With [18F]F-AraG in Urothelial Carcinoma Patients Receiving Neoadjuvant Therapy or Patients With Cancer Receiving Standard of Care Anti-PD-1/L1
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: Fluorine F 18 Ara-G|PROCEDURE: Positron Emission Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: tAN to Mitigate Withdrawal Behaviors in Neonates
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: DEVICE: Spark Biomedical Roo Transcutaneous Auricular Neurostimulation (tAN) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: Calcipotriene plus betamethasone dipropionate ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Motor Learning in Children With Cerebral Palsy Using Transcranial Direct-current Stimulation
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: active transcranial direct current stimulation|BEHAVIORAL: Motor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Brain Stimulation for Gait Improvement in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Functional Improvement
Interventions: DEVICE: rTMS|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Therapy for Autonomic Function & Mood in ICD Patients
Status: COMPLETED
Conditions: Ventricular Arrhythmia|Implantable Cardioverter Defibrillator
Interventions: BEHAVIORAL: Quality of Life Therapy (QOLT)|BEHAVIORAL: Heart Healthy Education (HHE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMPAGUM: Effects of Empagliflozin on Gut Microbiota in Heart Failure With a Preserved Ejection Fraction
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Empagliflozin 10 Mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Managing Minds at Work: A Feasibility Pilot Trial
Status: COMPLETED
Conditions: Occupational Stress|Occupational Neurosis|Mental Health Wellness 1|Absence|Sickness Behavior
Interventions: BEHAVIORAL: Managing Minds at Work Online Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Relative Bioavailability Study of Two Ropinirole 0.25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ropinirole HCl 0.25 mg Tablets|DRUG: Requip® 0.25 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Insoles Provided to Patients With Diabetes. A Longitudinal Randomized Controlled Study in Gothenburg
Status: COMPLETED
Conditions: Diabetic Foot|Neuropathy|Quality of Life
Interventions: OTHER: Custom made insoles 35 shore|OTHER: Prefabricated insoles|OTHER: 55 shore Custom made insole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Tablet Education to Advance Caregiver Health
Status: COMPLETED
Conditions: Dementia
Interventions: BEHAVIORAL: Education and Skill Building Rehabilitation-mobile (ESBR-m)|BEHAVIORAL: Usual Care (UC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine, Fluarix®/Influsplit SSW® (2013/2014 Season), in Adults 18 Years of Age and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix/Influsplit SSW® (2013-2014 season)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A 4-week Dose-Ranging, Dose-Interval, Efficacy, Safety and Tolerability Study of GSK961081 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK961081|DRUG: Salmeterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy Technique Decreases Respiratory Complications After Cardiac Operation
Status: COMPLETED
Conditions: Pneumonia|Pleural Effusion|Atelectasis
Interventions: PROCEDURE: Continuous Positive Airway Pressure (CPAP) facial mask|PROCEDURE: Assisted deep inspiration technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parkinson's Disease Therapy Using Cell Technology
Status: UNKNOWN
Conditions: Transplantation:Mesenchymal Stem Cell Transplantation
Interventions: BIOLOGICAL: Autologous mesenchymal stem cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide and the Autonomic Nervous System
Status: COMPLETED
Conditions: Hypertension|Pure Autonomic Failure
Interventions: DRUG: L-NMMA|DRUG: Trimethaphan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Powered Bone Marrow Aspiration and Core Biopsy System Compared to Manual Devices
Status: COMPLETED
Conditions: Bone Marrow Biopsy Procedures
Interventions: DEVICE: OnControl Bone Marrow Biopsy and Aspiration System|DEVICE: Manual bone marrow sampling device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Salmeterol on Eosinophil (EOS) Function
Status: COMPLETED
Conditions: Allergic Asthma
Interventions: DRUG: salmeterol|DRUG: Fluticasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Health Facility-based and Community-based Care for Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|Quality of Health Care|Community Health Care|Volunteer Health Workers|Tuberculosis Treatment Effectiveness
Interventions: OTHER: Health workers TB care group|OTHER: Community health workers TB care group|OTHER: Self-administered treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial to Establish the Equivalence Between ANDY-Disc® and Ultrabag® in Patients on CAPD.
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: DEVICE: Baxter's UltraBag® and FMC Andy·Disc®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases
Status: COMPLETED
Conditions: Laparoscopic Hysterectomy|Magnesium Sulfate|General Anesthesia
Interventions: DRUG: magnesium sulfate group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 4DX Functional Lung Imaging in the Diagnosis of Chronic Lung Allograft Dysfunction After Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplant; Complications
Interventions: DIAGNOSTIC_TEST: Fluoroscopic chest imaging with 4Dx technology software analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to Bone
Status: TERMINATED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ulipristal Use in Chinese Population
Status: TERMINATED
Conditions: Fibroid
Interventions: DRUG: Ulipristal acetate|OTHER: Placebo pills|DRUG: Ferrous sulphate|DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of CG200745 'Ivaltinostat' Oral Capsule
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematologic Malignancy|Solid Tumor|Fibrosis
Interventions: DRUG: Ivaltinostat|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polymer Clips Vs Endoloop for Appendicular Stump Ligation
Status: COMPLETED
Conditions: Appendicitis|Polymer Clips|Surgitie
Interventions: DEVICE: polymer clip|DEVICE: endoloop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lubiprostone for Treatment of Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: Placebo|DRUG: Lubiprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pain Sensation During Single Use of Two Topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Status: UNKNOWN
Conditions: Pain
Interventions: DRUG: Nevanac|DRUG: Acular LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye.
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: CP-690,550|DRUG: Cyclosporine|DRUG: CP-690,550 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, 18FDG-PET Pharmacodynamic Assessment of the Effect of BIIB021 in Subjects With Gastrointestinal Stromal Tumors (GIST)
Status: COMPLETED
Conditions: GIST
Interventions: DRUG: BIIB021
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Immune Effects of Acupuncture in Patients With Comorbid Chronic Pain and Major Depression Disorder
Status: RECRUITING
Conditions: Chronic Pain|Depression
Interventions: OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survival of Endocrowns Made From Different Ceramics
Status: COMPLETED
Conditions: Pulp Disease, Dental|Dental Caries|Dental Leakage
Interventions: DEVICE: Dental prosthesis|DEVICE: Dental crown|DEVICE: Hybrid ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Methylnaltrexone Bromide (MNTX) in Participants With Advanced Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Methylnaltrexone bromide (MNTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma-Recurrent|Diffuse Large B-Cell Lymphoma-Recurrent|Follicular Lymphoma-Recurrent|High Grade B-Cell Lymphoma-Recurrent|Primary Mediastinal Large B-Cell Lymphoma-Recurrent|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma-Recurrent|B-Cell Non-Hodgkin Lymphoma-Refractory|Diffuse Large B-Cell Lymphoma-Refractory|Follicular Lymphoma-Refractory|High Grade B-Cell Lymphoma-Refractory|Primary Mediastinal Large B-Cell Lymphoma-Refractory|Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma-Refractory
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Golcadomide|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study
Status: TERMINATED
Conditions: Acute Heart Failure|Decompensated Heart Failure
Interventions: COMBINATION_PRODUCT: subcutaneous furosemide and sc2wear device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gefitinib, Cisplatin, Irinotecan, and Radiation Therapy Before Surgery in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: gefitinib|DRUG: irinotecan hydrochloride|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Irrational Antimicrobial Use in Bangladesh: A Digital Intervention Program
Status: RECRUITING
Conditions: Resistance Bacterial|Increased Drug Resistance|Drug Resistance, Microbial
Interventions: COMBINATION_PRODUCT: SmartAMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Non-inferiority Study to Evaluate the Efficacy, Safety, and Tolerability of Combination Dry Powder of Fluticasone Propionate and Salmeterol (FSC) 250/50 Microgram (mcg) Twice Daily (BID) in Adults and Adolescents With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polypropylene Meshes in Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernias
Interventions: PROCEDURE: two different meshes in the repair of inguinal hernias
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Placebo|DRUG: PF-06835919|DRUG: PF-06835919
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE