pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Implementing Screening for Cannabis and Other Drug Use Disorders in Primary Care: Impact on Diagnosis and Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Cannabis-Related Disorder|Cannabis Abuse|Drug Abuse|Drug Use Disorders|Opioid Use Disorder|Opioid Abuse|Substance Abuse|Substance Use Disorders
Interventions: OTHER: Care Delivery Improvement Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Application of Esketamine in Anesthesia of Autism Children
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: propofol combined with esketamine|DRUG: propofol-sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Cardiovascular Risk Factors in Incident Dialysis Patients
Status: RECRUITING
Conditions: Chronic Kidney Disease
Interventions: BIOLOGICAL: Plasma osteoprotegerin level|BIOLOGICAL: Plasma fibroblast growth factor 23 level|PROCEDURE: Vascular calcification score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Different Ventilator Hyperinflation Maneuvers
Status: COMPLETED
Conditions: Infections, Respiratory|Ventilator Associated Pneumonia
Interventions: OTHER: VCV20|OTHER: VCV40|OTHER: PCV|OTHER: PCV+Tins|OTHER: PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ultrasound Assessment of the Subclavian Vein for Predicting Hypotension in Children After Anaesthesia Induction
Status: COMPLETED
Conditions: Anesthesia Complication|Hypotension on Induction|Hypovolemia
Interventions: OTHER: Ultrasound assessment of SCV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation iNduction, Consolidation and Maintenance Treatment With Isatuximab , Carfilzomib, LEnalidomide and Dexamethasone
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Isatuximab|DRUG: Carfilzomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase 2
Status: COMPLETED
Conditions: Antibiotic Initiation|Antibiotic Duration
Interventions: BEHAVIORAL: Social Comparison Email vs. Standard Email|BEHAVIORAL: Maintenance Certification Email vs. Standard Email|BEHAVIORAL: Report Opening Status Email vs. Standard Email (among previous report openers and non-openers)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delivering Empowering Conversations About Obstetric Regional Anesthesia for Underserved Minorities
Status: RECRUITING
Conditions: Postpartum Recovery
Interventions: OTHER: Disparities Conversation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Blosozumab (LY2541546) in Postmenopausal Female Participants
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Blosozumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Patients With Nephrogenic Systemic Fibrosis With Glivec
Status: COMPLETED
Conditions: Nephrogenic Systemic Fibrosis
Interventions: DRUG: Imatinib mesylate (Glivec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective Effects of Electroacupuncture Pretreatment Against Coronary Stenting
Status: UNKNOWN
Conditions: Myocardial Injury
Interventions: PROCEDURE: Electroacupuncture stimulation|PROCEDURE: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation Of The Impact Of A Call Center In Management Of Metastatic And/Or Advanced Renal Cell Carcinoma Patients Treated With Sunitinib (Sutent) In First Line
Status: COMPLETED
Conditions: Metastatic/Advanced Renal Cell Carcinoma
Interventions: OTHER: Best supportive care|OTHER: call center
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Confirmatory Clinical Study in NSCLC Patients With MET Exon 14 Mutation (KUNPENG-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: PLB1001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda
Status: RECRUITING
Conditions: Tuberculosis
Interventions: BEHAVIORAL: SMS|BEHAVIORAL: Phone call|BEHAVIORAL: Mobile money incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Entonox on Stages of Labor in Nulliparous Women
Status: COMPLETED
Conditions: ENTONOX|Nulliparous|Duration of Labor
Interventions: DRUG: Entonox|DRUG: Not receive Entonox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: AK112|DRUG: AK117|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serbian Smoking Reduction/Cessation Trial (2SRT)
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: OTHER: Swedish snus (smokeless tobacco)|OTHER: Onico
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Broccoli Sprout Extract and Probiotics for Eradication of Helicobacter Pylori
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Probiotics|DIETARY_SUPPLEMENT: Broccoli|DRUG: Esomeprazole|DRUG: Amoxicillin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SLAP Lesions; a Comparison of Conservative and Operative Treatment. A Prospective, Randomized Study
Status: COMPLETED
Conditions: SLAP Lesions
Interventions: PROCEDURE: labral repair|PROCEDURE: biceps tenodesis|PROCEDURE: diagnostic arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of [S,S]-Reboxetine in Patients With Postherpetic Neuralgia, Who Are Gabapentin Treatment Failures
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: [S,S]-Reboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acu-Transcutaneous Electrical Nerve Stimulation (TENS) on Post-Exercise Expiratory Flow Rate in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clean Catch Urine Feasibility and Contamination Rate Compared to Bladder Catheterization Urine in Pre-Continent Children
Status: NOT_YET_RECRUITING
Conditions: Urinary Tract Infections
Interventions: PROCEDURE: Bladder catheterization|PROCEDURE: clean catch urine via bladder massage technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Relapse Rate in Hepatitis C Patients Treated With Peginterferon Alfa-2b Plus Ribavirin in Common Clinical Practice in France (P05484)(Completed)
Status: TERMINATED
Conditions: Hepatitis C|Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peg-IFN alfa-2b|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers
Status: UNKNOWN
Conditions: Airway Responses|Hemodynamic
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Fentanyl Citrate Injection|COMBINATION_PRODUCT: dexmedetomidine and fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Astegolimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIS Monitoring of the Depth of Anaesthesia in Children
Status: COMPLETED
Conditions: General Surgery|Anaesthesia
Interventions: PROCEDURE: BIS Group|PROCEDURE: Non-BIS Group|DRUG: Anaesthetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Bowel Preparations in Magnetically Controlled Capsule Endoscopy
Status: RECRUITING
Conditions: Magnetically Controlled Capsule Endoscopy|Bowel Preparation
Interventions: DRUG: Polyethylene Glycol Electrolytes Powder (II)|OTHER: Low residue diet|OTHER: Normal diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: CSL Behring Sclero XIII
Status: UNKNOWN
Conditions: Systemic Sclerosis
Interventions: DRUG: Fibrogammin®P, coagulation factor XIII concentrate (Human)|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Mass Babance and Biotransformation of [14C]SHR6390 in Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: Healthy Adult Male Volunteers
Interventions: DRUG: [14C]SHR6390
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using Ultrasound Spectrum Analysis (USA) to Guide Dose Escalated Prostate Brachytherapy
Status: COMPLETED
Conditions: Clinical Stage T2b or Less of Prostate Cancer|Prostate Brachytherapy|Transrectal Prostate Ultrasound Treatment Planning
Interventions: OTHER: An ultrasound-based technique to identify prostate cancer|OTHER: pre-implant transrectal ultrasound images and planning|OTHER: ultrasound-based cancer-specific images
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amniotic Membrane Treatment for Hyposecretory Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes|Sjogren Syndrome With Keratoconjunctivitis
Interventions: BIOLOGICAL: Amniotic membrane extract eye drops (AMEED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RC48-ADC Combined With S-1 for First-line Treatment of Advanced Gastroesophageal Adenocarcinoma With Moderate Expression of HER2
Status: RECRUITING
Conditions: Advanced Gastroesophageal Adenocarcinoma
Interventions: DRUG: RC48-ADC|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety, Tolerability, and PK of HLX43 in Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: HLX43
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standardization of Mid-Level Providers Using Point of Care Ultrasound to Diagnose Pediatric Pneumonia
Status: UNKNOWN
Conditions: Pneumonia|Pediatric Disorder|Diagnostic and Monitoring Radiological Devices Associated With Adverse Incidents
Interventions: DEVICE: Point of care ultrasound training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of the Sufentanil NanoTab PCA System/15 mcg (Zalviso™) for the Treatment of Post-Operative Pain in Patients After Open Abdominal Surgery
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Sufentanil NanoTab PCA System/15 mcg|DRUG: Placebo Sufentanil NanoTab PCA System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Febuxostat on Coronary Plaque Volume in Patients With Chronic Stable Angina and Hyperuricemia
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Febuxostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hybrid Effectiveness-Implementation Study to Improve Clopidogrel Adherence
Status: COMPLETED
Conditions: Cardiovascular Disease|Acute Coronary Syndrome
Interventions: OTHER: Multifaceted Intervention with pharmacist and IVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Physiology of Human Brain Connectivity
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Single-pulse transcranial magnetic stimulation (spTMS)|DEVICE: Paired associative stimulation (PAS)|DIAGNOSTIC_TEST: Magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Opioid-free Anesthesia and Acute Postoperative Pain
Status: UNKNOWN
Conditions: Anesthesia|Postoperative Pain|Cognitive Impairment, Variable
Interventions: DEVICE: OFA|DRUG: OBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acid on Vitamin D Activation
Status: COMPLETED
Conditions: Hemodialysis Patients|Vitamin D Insufficiency|Vitamin D Deficiency
Interventions: DRUG: Omega-3 fatty acid ethylester 90|OTHER: Olive oil|OTHER: cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if Tissue Scored With a Scalpel Results in Any Noticeable Marks
Status: COMPLETED
Conditions: Skin Cancer
Interventions: DEVICE: Scalpel for tissue scoring|DEVICE: Surgical marker for tissue marking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
Status: COMPLETED
Conditions: Oral Mucositis|Pediatric Cancer
Interventions: DRUG: Curcumin|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of the ERK1/2 Inhibitor BVD-523 in Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: BVD-523
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TROPION-Lung05)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: DS-1062a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies
Status: RECRUITING
Conditions: NAFLD - Nonalcoholic Fatty Liver Disease|Diabetes|Obesity|Metabolic Syndrome|Cirrhosis|Liver Cancer|NASH - Nonalcoholic Steatohepatitis|HCC - Hepatocellular Carcinoma|Fatty Liver
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Safety of Fevipiprant in Patients With Renal Impairment Compared to Matched Healthy Subjects
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: QAW039|DRUG: QAW39A|DRUG: QAW39A2107|DRUG: QAW39A2107
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.
Status: RECRUITING
Conditions: Prostate Cancer|Radiotherapy Side Effect|Hypofractionation|Brachytherapy|Radiotherapy|Localized Prostate Carcinoma
Interventions: RADIATION: grade and compare reported side effects between groups
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects
Status: COMPLETED
Conditions: Satiety Response|Carbohydrate Metabolism|Sodium Retention
Interventions: OTHER: Seawater Pizza|OTHER: Standard pizza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of a Dexamethasone Drug Delivery System for Postoperative Inflammation and Pain After Cataract Surgery
Status: TERMINATED
Conditions: Cataract
Interventions: DRUG: Dexamethasone Drug Delivery System|DRUG: Placebo Drug Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gadolinium Deposits in Healthy Women Participating in a High Risk Screening Program for Early Breast Cancer Detection
Status: UNKNOWN
Conditions: Gd-based Contrast Media Exposure During Breast MRI Scans
Interventions: DIAGNOSTIC_TEST: Brain MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prophylactic nCPAP in the PACU Following Elective Laparotomy for Bowel Surgery
Status: COMPLETED
Conditions: Postoperative Pulmonary Atelectasis|Surgery
Interventions: DEVICE: Nasal Continuous Positive Airway Pressure|DEVICE: Low Flow Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.
Status: COMPLETED
Conditions: HER2-ve Metastatic Breast Cancer|Germline BRCA1/2 Mutations|Somatic BRCA1/2 Mutations
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KYMA Device: External Measure of Thoracic Fluid and Vital Signs
Status: COMPLETED
Conditions: Congestive Heart Failure(CHF)
Interventions: DEVICE: Kyma Device u-Cor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Adding Scapular Stabilization Exercises to Postural Correctional Exercises on on Forward Head Posture
Status: UNKNOWN
Conditions: Forward Head Posture
Interventions: OTHER: scapular stabilization exercise|OTHER: postural correction exercise|OTHER: advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic, Endocrine and Appetite-related Responses in Healthy, Adolescent Males After Acute and Daily Milk Consumption
Status: COMPLETED
Conditions: Appetite Regulation
Interventions: OTHER: milk|OTHER: orange fruit-juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The No Means No South Africa Evaluation Study
Status: COMPLETED
Conditions: Gender-based Violence|Sexual Violence
Interventions: BEHAVIORAL: No Means No intervention Girls' Curriculum|BEHAVIORAL: No Means No intervention Boys' Curriculum|BEHAVIORAL: Active comparator: Life Orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Erector Spinae Plane Block and Ankle and Foot Surgery
Status: COMPLETED
Conditions: Pain|Ankle Injuries
Interventions: DEVICE: Ultrasound|DRUG: Bupivacaine Hydrochloride|DRUG: saline solution|DEVICE: Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Influence of Injection Speed on Pain During Administration of Local Anaesthetic.
Status: COMPLETED
Conditions: Needlestick Injuries
Interventions: PROCEDURE: Normal speed lidocaine injection|PROCEDURE: Slow lidocaine injection|PROCEDURE: Fast lidocaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tilt and Tumble vs Divide and Conquer - a Unique Comparison of the Two Cataract Surgery Methods
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: Tilt and Tumble|PROCEDURE: Divide and Conquer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROmyBETAappGame: a Study to Learn More About the Medication Usage & Patient Reported Outcomes Via the myBETAapp and to Find Out More About the Usage of Game Principles and Game Design Elements (Gamification) in Medical Care of Patients With Multiple Sclerosis Treated With Betaferon
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: myBETAapp|OTHER: PEAK|DRUG: Betaferon, BAY86-5046|DEVICE: BETACONNECT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Transcutaneous Electrical Diaphragmatic Stimulation on Respiratory Variables in COPD Patients
Status: UNKNOWN
Conditions: COPD
Interventions: OTHER: TEDS in COPD patients|OTHER: TEDS in healthy patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Study to Gather More Information About the Safety of ACZONE Gel, 5% in Treating Subjects With Acne Who Have G6PD Deficiency
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: ACZONE Gel, 5%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: G-CSF+Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Allogeneic Hematopoietic Stem Cell Transplantation|Conditioning
Interventions: DRUG: Decitabine|DRUG: Busulfan (BU)|DRUG: Cyclophosphamide (CY)|DRUG: Granulocyte Colony-Stimulating Factor(G-CSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Different Diagnostic Coronary Catheters Over the Radial Access - the UDDC - Radial Trial
Status: COMPLETED
Conditions: Stable Coronary Heart Disease
Interventions: DEVICE: One-catheter concept|DEVICE: Standard catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Closed-loop FiO2 Controller With Conventional Control of FiO2
Status: COMPLETED
Conditions: Acute Respiratory Failure|Acute Hypoxemic Respiratory Failure|Acute Hypoxemic and Hypercapnic Respiratory Failure
Interventions: DEVICE: Activate FiO2 controller|DEVICE: Deactivate FiO2 controller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hypno-breastfeeding and Solution-oriented Approach
Status: COMPLETED
Conditions: Breastfeeding|Breast Milk Expression
Interventions: OTHER: Solution-oriented approach|OTHER: Hypno-breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: COVID-19 Pandemic and Parents of Disabled Children
Status: COMPLETED
Conditions: COVID-19|Disabilities Multiple|Cerebral Palsy|Muscular Dystrophies
Interventions: OTHER: Difficulties lived by disabled children's parents in the period of COVID-19 pandemic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Hysterosalpingo-Foam Ultrasonography Combined With Power Doppler, Compared With Laparoscopy in Tubal Patency Assessment in Cases of Infertility
Status: COMPLETED
Conditions: Infertility of Tubal Origin
Interventions: PROCEDURE: Hysterosalpingo-Foam Ultrasonography|PROCEDURE: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunotherapy With Neo-adjuvant Chemotherapy for OVarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: ARM A Durvalumab/chemotherapy association|DRUG: ARM B Durvalumab/Tremelimumab/chemotherapy association
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TriNav Infusion System for the Evaluation of Fidelity Between 99mTc-MAA and Y90-Microspheres Hepatic Distribution for Dosimetry Treatment Planning
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer
Interventions: DEVICE: TriSalus™ TriNav™Infusion System|DIAGNOSTIC_TEST: Angiogram|PROCEDURE: Y90-radioembolization procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events
Status: COMPLETED
Conditions: Thalassemia
Interventions: DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Determining the Effectiveness of Working Out Dads to Reduce Mental Health Difficulties in Fathers of Young Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: Working Out Dads|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Capecitabine in Treating Patients With Advanced and/or Inoperable Cholangiocarcinoma or Carcinoma of the Gallbladder
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer
Interventions: DRUG: capecitabine|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor|Prostate Cancer|Pancreas Cancer|Breast Cancer|Ovarian Cancer|Homologous Recombination Deficiency
Interventions: DRUG: MOMA-313|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H7N9 Mix and Match With MF59 in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013|DRUG: MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sibling and Unrelated Donor Hematopoietic Cell Transplant in Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Disease|Myelodysplastic Syndromes|Leukemia, Myeloid, Chronic|Myeloproliferative Disorders|Blood and Marrow Transplant (BMT)|Myelodysplastic Syndromes (MDS)|Leukemia
Interventions: PROCEDURE: ablative allogeneic hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Efficacy of Rilpivirine in Treatment-naive Indian Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Status: TERMINATED
Conditions: Human Immunodeficiency Virus Infections
Interventions: DRUG: Rilpivirine 25 mg|DRUG: Tenofovir Disoproxil Fumarate (TDF)/Lamivudine (3TC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of tDCS on Depressive Symptoms of Participants With Temporal Lobe Epilepsy
Status: UNKNOWN
Conditions: Depressive Symptoms|Epilepsy, Temporal Lobe
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ropivacaine Continuous Wound Infusion Versus Intrathecal Morphine for Postoperative Analgesia After Cesarean Delivery
Status: COMPLETED
Conditions: Obstetric Pain
Interventions: DEVICE: wound infusion (Dosi-Pain® Kit, LEVENTON SAU, Spain)|PROCEDURE: Spinal Anesthesia|DRUG: intrathecal morphine|DRUG: Ropivacaine (Ropivacaina Molteni®)|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF NEUROMUSCULAR ELECTRICAL STIMULATION ON DYSPHAGIA IN CHILDREN WITH DOWN SYNDROME
Status: UNKNOWN
Conditions: Rehabilitation
Interventions: OTHER: oral motor training|DEVICE: Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of U101 for Bladder Pain and/or Urgency
Status: COMPLETED
Conditions: Pelvic Pain|Interstitial Cystitis|Bladder Diseases
Interventions: DRUG: Alkalinized Lidocaine-Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.
Status: COMPLETED
Conditions: Transient Insomnia
Interventions: DRUG: SM-1|DRUG: D+Z|DRUG: D+L|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the AcuFocus Corneal Inlay ACI7000PDT in Presbyopes
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: AcuFocus Corneal Inlay ACI 7000PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Value and Mechanism of Recombinant Human Interleukin-2 in Children With Henoch-schönlein Purpura
Status: COMPLETED
Conditions: Purpura, Schoenlein-Henoch
Interventions: DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azopt (Brinzolamide 1.0%) Plus Travatan (Travoprost 0.004%) in Treating Patients With Chronic Angle-Closure Glaucoma (CACG)
Status: TERMINATED
Conditions: Intraocular Pressure
Interventions: DRUG: Travoprost 0.004% + Brinzolamide 1.0%|DRUG: Travoprost 0.004% + Tears Natural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapamycin Versus Mycophenolate Mofetil in Kidney-Pancreas Recipients
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Rapamycin|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
Status: COMPLETED
Conditions: Anxiety|Postoperative Pain|Bleeding
Interventions: DRUG: Fentanyl|DRUG: Dexmedetomidine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Patients With Hallucinations and Delusions Associated With Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease|Dementia
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine in Treating Patients With Persistent or Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Recurrent Cervical Carcinoma
Interventions: DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis
Status: RECRUITING
Conditions: Bacterial Vaginoses
Interventions: DEVICE: vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Anti TNF Alpha Therapy And Their Adverse Effects In Ankylosing Spondylitis In A North Indian Population
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: anti TNF alpha agent|DRUG: Anti TNF alpha therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease|Inflammatory Bowel Diseases|Crohn Disease of Small Intestine|Crohn Colitis|Crohn's Ileocolitis|Crohn Disease in Remission
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitive Behavior Group Therapy in Adolescents With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: cognitive behavior group therapy|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Dignity, Meaningfulness and Mental Well-Being
Status: COMPLETED
Conditions: Life-limiting Serious Illness
Interventions: PROCEDURE: Dignity Therapy (DT) module|PROCEDURE: CALM Therapy module|PROCEDURE: Mindfulness-based interventions module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Study of Immune Function and PD-1 Antibody Therapy Efficacy Predictors on CAEBV and EBV-HLH Patients
Status: RECRUITING
Conditions: Secondary Hemophagocytic Lymphohistiocytosis|Chronic Active Epstein-Barr Virus Infection
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Study to Evaluate the Efficacy and Safety of Penpulimab in the Relapsed and Refractory Classical Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Hodgkin Disease Lymphoma
Interventions: DRUG: Penpulimab|DRUG: Investigator's choice of Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognition and Emotion in the SII and IBD
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Inflammatory Bowel Disease (IBD)|Crohn's Disease(CD)|Ulcerative Colitis
Interventions: BEHAVIORAL: emotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
Status: COMPLETED
Conditions: Cardiac Catheterization|Blood Pressure|Heart Ventricles|Echocardiography|Heart Failure
Interventions: DRUG: Definity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Multifunctional Nutrition Tube on Cerebral Small Vessel Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|DEVICE: Nasogastric Tube Feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: Pilocarpine HCl Ophthalmic Solution|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ciclosporin in the Management of New Erythema Nodosum Leprosum
Status: COMPLETED
Conditions: Leprosy
Interventions: DRUG: Ciclosporin|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Physical Intervention for Persistent Post-Concussive Symptoms
Status: WITHDRAWN
Conditions: Persistent Post-Concussive Syndrome
Interventions: OTHER: Aerobic exercise and balance retraining|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for Smoking in Substance Abusers
Status: COMPLETED
Conditions: Substance Abuse
Interventions: DRUG: Nicotine Replacement Treatment (NRT)|BEHAVIORAL: Brief Advice|BEHAVIORAL: Contingency Management|BEHAVIORAL: Non-Contingent Reinforcement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation
Status: RECRUITING
Conditions: Alveolar Ridge Enlargement
Interventions: PROCEDURE: Premolar extraction and socked preservation with L-PRF|PROCEDURE: Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
Status: COMPLETED
Conditions: Erythema|Sun Damaged Skin|Skin Inflammation
Interventions: OTHER: Topical Placebo Cream|OTHER: Topical Cream with 0.5% Active|OTHER: Topical Cream with 1% Active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Trial of Apatinib Plus Docetaxel in Locally Advanced or Metastatic Gastric or GEJ Adenocarcinoma
Status: UNKNOWN
Conditions: Metastatic Gastric Adenocarcinoma
Interventions: DRUG: Apatinib|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focused Field of View Calcium Scoring Prior to Coronary CT Angiography
Status: COMPLETED
Conditions: Radiation Safety|Coronary Computed Tomography Angiography|Coronary Artery Disease
Interventions: RADIATION: Field of View
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Integrating Whole Genome Sequencing and Digital Twins Into the Management of Hypercholesterolemia in Emiratis
Status: RECRUITING
Conditions: Hypercholesterolemia, Autosomal Dominant|Hypercholesterolemia, Autosomal Recessive|Familial Combined Hypercholesterolemia
Interventions: GENETIC: Whole Genome Sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Patient-centered Outcomes During Using Self-ligating Brackets With or Without Piezocision vs Traditional Brackets
Status: COMPLETED
Conditions: Crowding, Tooth
Interventions: DEVICE: Traditional braces|DEVICE: Self-ligating braces|PROCEDURE: Self-ligating braces + piezocision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Suvorexant for Reduction of Brain Reactivity in Patients with Cannabis Use Disorder (Pilot Study)
Status: NOT_YET_RECRUITING
Conditions: Cue-reactivity|Cannabis Use Disorder|Functional MRI|Orexin Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gemcitabine and Mitoxantrone in Treating Patients With Relapsed Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Gemcitabine Hydrochloride|DRUG: Mitoxantrone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Ziprasidone (Geodon) for the Depressive Mixed State
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression|Depression
Interventions: DRUG: ziprasidone (Geodon)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Of Vision Recovery And Comfort Index In Patients With Borderline/Mild Dry Eyes Undergoing FLACS With Premium IOL
Status: UNKNOWN
Conditions: Dry Eye Syndromes
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Prednisolone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Treatment Outcomes of Two Interventional Pain Procedures in Chronic Coccygodynia
Status: COMPLETED
Conditions: Tailbone Disorders
Interventions: PROCEDURE: Fluoroscopy-guided ganglion impar block|PROCEDURE: Fluoroscopy-guided caudal epidural steroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PFI Hazardous Drinkers With Subclinical PTSD
Status: UNKNOWN
Conditions: Hazardous Drinking|Posttraumatic Stress Disorder
Interventions: OTHER: Alcohol-PTSD-PFI (AP-PFI)|OTHER: Active Comparison Condition (C-PFI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Efpeglenatide|DRUG: Dulaglutide|DRUG: Background therapy Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040)
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Cancer
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Methotrexate|DRUG: Docetaxel|BIOLOGICAL: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on Bone Mineral Density (BMD) of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG/EE (292005)(P05765)(COMPLETED)
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: NOMAC-E2|DRUG: LNG-EE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION