pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Determine Absorption, Metabolism, and Excretion of [14C]-SAR439859, and to Assess Absolute Oral Bioavailability of Amcenestrant (SAR439859), in Healthy Post-menopausal Women
Status: COMPLETED
Conditions: Breast Cancer|Healthy Volunteers
Interventions: DRUG: amcenestrant|DRUG: [14C]-SAR439859 microtracer|DRUG: [14C]-SAR439859
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Retrospective Study on the Relationship Between Donor Leukocyte Telomere Length and Prognosis of Acute Leukemia Patients Treated With Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Acute Leukemia
Interventions: OTHER: No intervention, observation study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glycaemic Response to High REsistant STarch Bread
Status: COMPLETED
Conditions: Blood Glucose Response
Interventions: OTHER: sbeIIa/b white bread|OTHER: Control white bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy
Status: COMPLETED
Conditions: Breast Cancer|Depression|Fatigue|Psychosocial Effects of Cancer and Its Treatment|Weight Changes
Interventions: BEHAVIORAL: exercise intervention|OTHER: questionnaire administration|PROCEDURE: CAM exercise therapy|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Therapy of HAIC and HLX10 and HLX04 in HCC With Major Portal Vein Tumor Thrombosis
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma With Major Portal Vein Thrombosis
Interventions: PROCEDURE: HAIC (Hepatic arterial infusion chemotherapy)|DRUG: HLX10 (PD-1 antibody)|DRUG: HLX04 (VEGF antibody)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Music as Pain Therapy in Patients Undergoing Laparoscopic Cholecystectomy in a Day Care Unit
Status: COMPLETED
Conditions: Pain|Ponv|Fatigue
Interventions: DEVICE: music pillow|DEVICE: pillow without music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Low Dose of HCG During Ovulation Induction With CC in Women With CC Resistant PCOS
Status: COMPLETED
Conditions: Infertility|Polycystic Ovarian Syndrome
Interventions: DRUG: Clomiphene citrate and Human chorionic gonadotropin (HCG)|DRUG: Clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Oseltamivir and Intravenous Zanamivir in Healthy Adults
Status: COMPLETED
Conditions: Influenza|Virus Diseases
Interventions: DRUG: Zanamivir|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serial Circulating Tumor DNA (ctDNA) Monitoring During Adjuvant Capecitabine in Early Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Breast Cancer
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PBM on Functional Capacity and Fatigability in Post Covid-19 Elderly
Status: UNKNOWN
Conditions: Post Covid-19 Elderly
Interventions: RADIATION: photobiomodulation|OTHER: placebo intervention by photobiomodulation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Desipramine Hydrochloride and Filgrastim For Stem Cell Mobilization in Patients With Multiple Myeloma Undergoing Stem Cell Transplant
Status: TERMINATED
Conditions: DS (Durie/Salmon) Stage I Plasma Cell Myeloma|DS Stage II Plasma Cell Myeloma|DS Stage III Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Desipramine Hydrochloride|BIOLOGICAL: Filgrastim|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children.
Status: RECRUITING
Conditions: Healthy Volunteers (Non-alcoholic Steatohepatitis)
Interventions: DRUG: NNC0194-0499|DRUG: ethinylestradiol/levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension
Status: COMPLETED
Conditions: Stage 1 Hypertension|Stage 2 Hypertension
Interventions: DRUG: Nebivolol and Valsartan 1|DRUG: Nebivolol and Valsartan 2|DRUG: Nebivolol and Valsartan 3|DRUG: Nebivolol 1|DRUG: Nebivolol 2|DRUG: Valsartan 1|DRUG: Valsartan 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Letrozole|DRUG: Goserelin|DRUG: Leuprolide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of MKC-1 Combined With Pemetrexed to Treat Advanced Cancer and Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: MKC-1|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adherus™ Dural Sealant in Spinal Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Duraplasty
Interventions: DEVICE: Adherus Dural Sealant System|DEVICE: DuraSeal Exact Dural Sealant System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Detecting and Treating High Blood Pressure in Aboriginal Population and Low and Middle Income Countries
Status: UNKNOWN
Conditions: Hypertension|Cardiovascular Disease|Diabetes
Interventions: OTHER: SMS text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aspirin Versus Clopidogrel Effect on Uterine Blood Flow in Women With Unexplained Recurrent Miscarriages
Status: UNKNOWN
Conditions: Recurrent Pregnancy Loss
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Crossover Bioequivalence Study of Irbesartan Hydrochlorothiazide 300/25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Irbesartan and Hydrochlorothiazide|DRUG: Avalide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Preventive Measures on Caries Progression in Mixed Dentition Patients.
Status: COMPLETED
Conditions: Dentist's Role
Interventions: DRUG: SDF1|DEVICE: Diode Laser|DRUG: Pit Fissure Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation/Expansion Study of Oral OP-1250 in Subjects With Advanced and/or Metastatic HR+, HER2- Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Receptor Positive Breast Carcinoma|HER2-negative Breast Cancer
Interventions: DRUG: OP-1250
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia
Status: TERMINATED
Conditions: Ventilator Associated Pneumonia|Prevention|Respiratory Infection Other
Interventions: DRUG: Aztreonam lysine|DEVICE: Aerogen Solo|DEVICE: CombiHaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families
Status: RECRUITING
Conditions: Child Safety|Coercion|Child Wellbeing|Adjustment|Parenting|Post Traumatic Stress Disorder|Mental Health|Child Maltreatment|Trauma|Emotional Regulation
Interventions: BEHAVIORAL: Online Parenting Program|OTHER: No online parenting program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficiency of Cognitive Group Therapy for Patient With Subjective Memory Complains Using the WebNeuro System From Brain Resource(BRC)
Status: UNKNOWN
Conditions: Subjective Memory Complains
Interventions: BEHAVIORAL: cognitive group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib (ACP-196), a Btk Inhibitor, for Treatment of de Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Activated B-cell Diffuse Large B-Cell Lymphoma (ABC DLBCL)
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Heterologous Prime-Boost Ebola Vaccine Regimens in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: MVA-BN-Filo|BIOLOGICAL: Ad26.ZEBOV|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab Plus Doxorubicin for the First Line Treatment of Adcanced Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Soft Tissue Sarcoma|Neoplasms, Connective and Soft Tissue|Sarcoma Metastatic|Sarcoma,Soft Tissue
Interventions: DRUG: Camrelizumab|DRUG: Adriamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and LENvatinib in Participants With Hepatocellular Carcinoma (HCC) Before Liver Transplant
Status: RECRUITING
Conditions: Liver Transplant; Complications|Hepatocellular Carcinoma Recurrent
Interventions: DRUG: Pembrolizumab Injection [Keytruda]|DRUG: Lenvatinib Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of rhHNS Administration Via an IDDD in Pediatric Patients With Early Stage MPS IIIA Disease
Status: COMPLETED
Conditions: Sanfilippo Syndrome
Interventions: DRUG: Recombinant human heparan N-sulfatase [rhHNS]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DEVICE: Cryosa Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor
Status: RECRUITING
Conditions: Ewing Sarcoma|Ewing-Like Sarcoma
Interventions: DRUG: LY2880070|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioefficiency of of Conventional Fish and Vitamin D Fortified Fish
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: OTHER: vitamin D fortified fish|OTHER: conventional fish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oxygen Concentration Target in Stroke Endovascular Treatment
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: OTHER: Normobaric high-concentration oxygen|OTHER: Normobaric low-concentration oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Smoking Cessation Intervention in a Mental Health Day Hospital
Status: RECRUITING
Conditions: Tobacco Use Disorder|Smoking Cessation|Mental Disorder
Interventions: BEHAVIORAL: Smoking cessation program|BEHAVIORAL: Placebo Comparator: Brief Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ciltacabtagene Autoleucel in High-Risk Smoldering Multiple Myeloma
Status: NOT_YET_RECRUITING
Conditions: High Risk Smoldering Multiple Myeloma
Interventions: DRUG: Group 1: Dara-VRD followed by apheresis and cilta-cel infusion|DRUG: Group 2: Apheresis followed by Dara-VRD and cilta-cel infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Desiccated Thyroid Extract Versus Synthetic T3/T4 Combination (ThyrolarTM) Versus L-T4 Alone in the Therapy of Primary Hypothyroidism With Special Attention to the Gene Polymorphism
Status: UNKNOWN
Conditions: Hypothyroidism
Interventions: DRUG: Levothyroxine|DRUG: Levothyroxine Plus Liothyronine|DRUG: Desiccated Thyroid Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise Training in Patients With Chronic Hepatitis B and Hepatic Steatosis
Status: COMPLETED
Conditions: Hepatitis B, Chronic|Hepatic Steatosis
Interventions: BEHAVIORAL: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Respiratory Failure|Respiratory Distress Syndrome|Respiratory Tract Diseases|Cytokine Storm
Interventions: DRUG: MRG-001 (Low-dose)|DRUG: MRG-001 (High-dose)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromonitoring During the Latarjet Procedure
Status: COMPLETED
Conditions: Shoulder Instability|Iatrogenic Nerve Injury
Interventions: DEVICE: Intra-operative neuromonitoring (XLTEK/NATUS EP Protektor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Norfloxacin in Secondary Prophylaxis for Spontaneous Bacterial Peritonitis
Status: COMPLETED
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: GMCSF|DRUG: Norfloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Adverse Events and Change in Disease Activity in Adult and Adolescent Participants With Acute Hepatitis C Virus (HCV) Infection on Treatment With Oral Tablets of Glecaprevir (GLE)/Pibrentasvir (PIB)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: Glecaprevir/Pibrentasvir (GLE/PIB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Juvista (Avotermin) in Scars Following Varicose Vein Removal
Status: COMPLETED
Conditions: Varicose Veins|Cicatrix
Interventions: DRUG: Avotermin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)
Status: RECRUITING
Conditions: AML, Adult Recurrent|MDS
Interventions: DRUG: LYT-200|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Two Different Needles in Subjects With Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoFine® needle 6 mm|DEVICE: NovoFine® needle 8 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QWISE - Study of Quinapril in Women With Chest Pain, Coronary Flow Reserve Limitations and Evidence of Myocardial Ischemia
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: DRUG: Quinapril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of ZG-801 for the Treatment of Hyperkalemia
Status: COMPLETED
Conditions: Hyperkalemia
Interventions: DRUG: patiromer|DRUG: patiromer|DRUG: placebo|DRUG: placebo|DRUG: patiromer|DRUG: patiromer|DRUG: patiromer|DRUG: patiromer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sperm Selection by Rheotaxis and Thermotaxis in In-Situ Handmade Microfluidics of Fluidic Walls in the Same ICSI Plate
Status: RECRUITING
Conditions: Intracytoplasmic Sperm Injection|Sperm|Microfluidics
Interventions: OTHER: Sperm selection for ICSI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Fluid Collection of the Chest in Children With Pneumonia
Status: COMPLETED
Conditions: Community Acquired Bacterial Pneumonia|Paraneumonic Effusion
Interventions: PROCEDURE: Video Assisted Thorascopic Surgery Thoracostomy Tube Placement & Drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sentinel Lymph Nodes in Head and Neck Squamous Cell Carcinoma
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)
Interventions: DRUG: Lymphoseek
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous, Non-Small-Cell Lung Cancer|Neoplasms
Interventions: DRUG: BI 836880|DRUG: ezabenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The LightPath® and 68Ga-RM2 in Breast Cancer Study
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: COMBINATION_PRODUCT: LightPath® Imaging System and 68Ga-RM2|DRUG: 68Ga-RM2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Regulation of Choroidal Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Status: COMPLETED
Conditions: Autoregulation
Interventions: PROCEDURE: Suction cup application|PROCEDURE: Squatting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Efficacy of Different Treatments in Patients With COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: DRUG: Emtricitabine/Tenofovir Disoproxil Fumarate 200 MG-245 MG Oral Tablet [TRUVADA]|DRUG: Baricitinib + dexamethasone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Picricum Acidum and Phosphoricum Acidum Homaccord on Perceived Levels of Anxiety in University Students
Status: COMPLETED
Conditions: Anxiety
Interventions: OTHER: Sucrose pillules|OTHER: Homeopathic homaccord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic CD30.CAR-EBVSTs in Patients With Relapsed or Refractory CD30-Positive Lymphomas
Status: RECRUITING
Conditions: Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type|Classical Hodgkin Lymphoma
Interventions: BIOLOGICAL: CD30.CAR-EBVST cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Amount of LY3074828 That Gets Into the Body When Given With LY9999QS, in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: LY3074828|BIOLOGICAL: LY900021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prognostic Determinants of Survival and Quality of Life in Prevalent End-stage Kidney Disease Patients
Status: COMPLETED
Conditions: Dialysis|Quality of Life|Nutrition
Interventions: OTHER: Blood sampling|OTHER: Nails collection|OTHER: Stool collection|OTHER: Physical Functioning|OTHER: Sleep
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electroacupuncture Therapy for Treating Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: PROCEDURE: EA combined with medication|DRUG: Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
Status: ENROLLING_BY_INVITATION
Conditions: Neurogenic Bladder|Neurogenic Bowel|Spina Bifida|Fecal Incontinence|Fecal Impaction|Urinary Incontinence
Interventions: DEVICE: Peristeen Transanal Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cinenses Lung Volume Reduction Reverser System First-in-man Study Treating Patients With Severe Emphysema
Status: UNKNOWN
Conditions: Emphysema
Interventions: DEVICE: Cinenses Lung Volume Reduction Reverser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability, and Pharmacokinetics of BIIB095 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: BIIB095|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Breathing, Sleep and the Effects of Continuous Positive Airway Pressure During Wakefulness in Children With Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Effect of CPAP on respiratory work and cardiac function indices during wakefulness|OTHER: Effect of CPAP on respiratory work and cardiac function indices during wakefulness|OTHER: Effect of CPAP on respiratory work and cardiac function indices during wakefulness|DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PD1 Antibody and Lenalidomide as a Treatment for EBV-HLH or CAEBV
Status: UNKNOWN
Conditions: EBV Infection
Interventions: DRUG: PD1 antibody|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Mocetinostat|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
Status: RECRUITING
Conditions: High Grade Glioma|Glioma|Glioma, Malignant|Glioblastoma
Interventions: DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ESWL vs. Pancreatoscopy-guided Lithotripsy for Painful Chronic Calcific Pancreatitis
Status: ENROLLING_BY_INVITATION
Conditions: Pancreatitis, Chronic
Interventions: PROCEDURE: Per-oral Pancreatoscopy-guided Lithotripsy|PROCEDURE: Extracorporeal Shock-Wave Lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Abuse Potential of Lyrica® in Healthy Non-Drug Dependent Recreational Opioid Users
Status: COMPLETED
Conditions: Abuse Potential
Interventions: DRUG: Pregabalin 300mg|DRUG: pregabalin 450 mg|DRUG: Pregabalin 300 mg with oxycodone 20 mg|DRUG: pregabalin 450 mg with oxycodone 20 mg|DRUG: oxycodone 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Xeloda (Capecitabine) in Breast Cancer Patients With Central Nervous System (CNS) Progression
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Dextrose Injection and Physical Therapy for Frozen Shoulder
Status: NOT_YET_RECRUITING
Conditions: Frozen Shoulder
Interventions: DRUG: 15% hypertonic dextrose|DRUG: Normal saline|OTHER: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Scalable Psychological Intervention to Reduce Psychological Distress Among Healthcare Workers
Status: COMPLETED
Conditions: Psychological Distress|Depression|Anxiety
Interventions: BEHAVIORAL: Doing What Matters (DWM)|BEHAVIORAL: Problem Management Plus (PM+)|BEHAVIORAL: Psychological First Aid (PFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Octafibrin for On-demand Treatment of Acute Bleeding and to Prevent Bleeding During and After Surgery
Status: COMPLETED
Conditions: Congenital Fibrinogen Deficiency
Interventions: DRUG: Octafibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ODiXahip - a Phase IIa Dose Escalating Proof of Principle Trial
Status: COMPLETED
Conditions: Thromboembolism|Prevention
Interventions: DRUG: Rivaroxaban (BAY59-7939)|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Efficacy and Safety of TLL-018 in CSU Participants
Status: NOT_YET_RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: TLL-018 tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 5-Aza for Post-Remission Therapy of Acute Myeloid Leukemia (AML) in Elderly Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Vidaza 100 milligram (mg) injection|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Endotracheal Balloon Dilator to Improve Patient Oxygenation and Allow Ventilation During Airway Procedures
Status: COMPLETED
Conditions: Tracheal Stenosis
Interventions: DEVICE: improved tracheal balloon dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Case Management for Crack Users Who Seek Treatment in CAPSad in Brazil
Status: UNKNOWN
Conditions: Crack Abuse or Dependence
Interventions: BEHAVIORAL: Case Management (Strength-Based)|BEHAVIORAL: Usual Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Extracorporeal Shock Wave Therapy After Botulinum Toxin Type A Injection for Post-stroke Spasticity
Status: COMPLETED
Conditions: Stroke|Hemiplegia, Spastic|Muscle Spasticity
Interventions: DEVICE: Extracorporeal shock wave therapy|PROCEDURE: Botulinum toxin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Trial Using Double-Bolus THR-100 Versus Streptokinase
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: THR-100|DRUG: Streptokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer
Status: COMPLETED
Conditions: Aerodigestive Tract Cancer|Lung Cancer|Esophageal Cancer|Head and Neck Cancer
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 1404003_OpenPsori.PlaqueTest to Eval.Eff.of Diff.Comp. to Mapracorat
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Mapracorat (ZK 245186, BAY 86-5319)|DRUG: Prednicarbate 0.25% ointment|DRUG: Clobetasol 0.05% ointment|DRUG: Calcipotriene 0.005% ointment|DRUG: Calcipotriene 0.005%/Betamethasone dipropionate 0.05% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Longo's Intervention in the Treatment of Hemorrhoids and Rectal Mucosal Prolapse
Status: COMPLETED
Conditions: Hemorrhoids|Rectal Mucosa Prolapse
Interventions: PROCEDURE: 4.5cm suture|PROCEDURE: 6cm suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Depression in HIV/HCV Co-infected Substance Abuse Patients
Status: TERMINATED
Conditions: Hepatitis C|Depressive Disorder, Major|Depressive Disorder|Depression|HIV Infections
Interventions: BEHAVIORAL: Hepatitis C educational support groups|BEHAVIORAL: Cognitive Behavioral Therapy skills based group sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Active External Rewarming on Rewarming Rate in Simulated Prehospital Accidental Hypothermia
Status: RECRUITING
Conditions: Accidental Hypothermia
Interventions: DEVICE: PAX Warming Blanket|DEVICE: Passive insulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)
Status: RECRUITING
Conditions: Pain Management
Interventions: DEVICE: BreEStim 240|DEVICE: EStim 240
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: L9LS MAb in Malian Infants
Status: RECRUITING
Conditions: Malaria
Interventions: BIOLOGICAL: L9LS|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Hemophilia A
Interventions: DRUG: Emicizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Efficacy and Safety of Generic Methylphenidate Prolong-released Comparison With Original
Status: UNKNOWN
Conditions: Adhd
Interventions: DRUG: prolong-release methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of Capivasertib on Midazolam in Patients With Advanced Solid Tumours
Status: COMPLETED
Conditions: Solid Tumour
Interventions: DRUG: Capivasertib|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC.
Status: RECRUITING
Conditions: Gastric Cancer|Microsatellite Instability
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Management of Chronic Pain and Symptoms Among Women Treated for Breast Cancer (Lymph-Flow)
Status: COMPLETED
Conditions: Breast Cancer|Pain|Lymphedema
Interventions: BEHAVIORAL: The-Optimal-Lymph-Flow|BEHAVIORAL: Arm Precaution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery
Status: NOT_YET_RECRUITING
Conditions: Malocclusion
Interventions: PROCEDURE: Orthodontic Molar Protraction and PAOO|PROCEDURE: Orthodontic Molar Protraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study to Assess the Effect of a Light Meal and a High-Fat Meal on the Absorption of BMS-986205 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986205
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: This Study Evaluates the Superiority of Daily Self-pH Monitorization of Lit-control®pH Meter Compared to the Monitorization of Reactive Strips (Standard of Care).
Status: UNKNOWN
Conditions: Cystinuria
Interventions: DEVICE: Lit-control®pH Meter|DIAGNOSTIC_TEST: Reactive strips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Efficacy and Safety of Alteplase in Participants With Mild Stroke
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: Alteplase|DRUG: Alteplase Placebo|DRUG: Aspirin|DRUG: Aspirin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine Patch in Veterans With Cognitive Impairment Following TBI
Status: COMPLETED
Conditions: Traumatic Brain Injury|Cognitive Impairment
Interventions: DRUG: Rivastigmine Transdermal Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Telehealth Lifestyle Intervention for Community-Dwelling Older Adults
Status: COMPLETED
Conditions: Lifestyle, Healthy|Quality of Life|Aging
Interventions: BEHAVIORAL: Holistic Occupational Performance Empowerment (HOPE) Lifestyle Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Sound Therapy on Chronic Primary Tinnitus
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DEVICE: CAABT|DEVICE: TMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study, Three Randomized Arms (R-CVP vs R-CHOP vs R-FM),for Patients With Stage II-IV Follicular Lymphoma
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: DRUG: R-CVP|DRUG: R-CHOP|DRUG: R-FM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CSE v. Epidural for Postpartum Depression
Status: COMPLETED
Conditions: Depression, Postpartum|Labor Pain
Interventions: PROCEDURE: CSE|PROCEDURE: Epidural|DRUG: Bupivacaine / fentaNYL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Hepatoblastoma|Previously Treated Childhood Rhabdomyosarcoma|Recurrent Childhood Liver Cancer|Recurrent Childhood Rhabdomyosarcoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Neuroblastoma|Recurrent Osteosarcoma|Rhabdomyosarcoma
Interventions: DRUG: Imetelstat Sodium|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differing Levels of Positive Anti-Neutrophil Cytoplasm Antibody (ANCA) Test and Their Correlation With Vasculitis or Malignancy or Chronic Inflammation
Status: UNKNOWN
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Interventions: OTHER: Follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter, Randomized Study of Early Assessment by CT Scanning in Severely Injured Trauma Patients
Status: COMPLETED
Conditions: Multiple Trauma/Injuries
Interventions: OTHER: Total body Computed Tomography.|OTHER: Conventional imaging and selective CT scanning.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.
Status: UNKNOWN
Conditions: Prostate Cancer|Benign Prostatic Hypertrophy|Bladder Stones|Kidney Stones
Interventions: DIAGNOSTIC_TEST: NV-VPAC1 PCa Urine Diagnostic Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
Status: RECRUITING
Conditions: Cryoglobulinemic Vasculitis (CV)|Drug-induced Vasculitis|Eosinophilic Granulomatosis With Polyangiitis (EGPA)|IgA Vasculitis|Isolated Cutaneous Vasculitis|Granulomatosis With Polyangiitis (GPA)|Microscopic Polyangiitis (MPA)|Polyarteritis Nodosa (PAN)|Urticarial Vasculitis|Vasculitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigating Neurocognitive, Motor and Biological Effects of MindLenses Professional in Neurological Diseases
Status: RECRUITING
Conditions: Stroke|Mild Cognitive Impairment
Interventions: DEVICE: MindLenses Professional|BEHAVIORAL: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microbial Basis of Systemic Malodor and "People Allergic To Me" Conditions
Status: COMPLETED
Conditions: Nutritional and Metabolic Diseases
Interventions: BEHAVIORAL: Nutritional counselling|BEHAVIORAL: Stress-reduction counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tranexamic Acid (TXA) and Corona Virus 2019 (COVID19) in Inpatients
Status: WITHDRAWN
Conditions: COVID19
Interventions: DRUG: Tranexamic acid|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Status: RECRUITING
Conditions: Metabolic Syndrome
Interventions: DRUG: Celery Seed|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strain and Blood Inflammatory Markers as Prognostic Tools for ARDS AMIS (ARDS - Markers of Inflammation - Strain)
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Inflammatory markers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: First-in-human Study to Investigate Safety, Blood Levels and Activity of MP0274 in Cancer Patients With HER2-positive Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: MP0274
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progesterone for Prevention of Preterm Birth in Women With Short Cervix: Randomized Controlled Trial
Status: COMPLETED
Conditions: Preterm Birth|Pregnancy Trimester, Second
Interventions: DRUG: Micronised progesterone (Utrogestan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of the Type and Emulsification of Dietary Fat on the Carotenoids Absorption
Status: COMPLETED
Conditions: Carotenoids
Interventions: OTHER: olive oil-water mixture|OTHER: olive oil-water emulsion|OTHER: coconut oil-water mixture|OTHER: coconut oil-water emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DEB for Symptomatic Intracranial Atherosclerosis Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Ischemia|Cerebral Atherosclerosis
Interventions: DEVICE: Drug eluting balloon (Vmoky)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Ziprasidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Social Cognition in Schizophrenia Trial
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Computerized plasticity-based adaptive cognitive training|OTHER: Commercially available computerized training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DEVICE: Active Intermittent theta burst stimulation|DEVICE: Sham Intermittent theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: NASHA/Dx (Solesta) Gel|DEVICE: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT