pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of TAK-875 (Fasiglifam) With Placebo in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: Fasiglifam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Clinical Trial Comparing Macular Photocoagulation With or Without Intravitreal Bevacizumab or Triamcinolone for the Treatment of Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Laser|DRUG: Bevacizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
Status: COMPLETED
Conditions: Muscle Atrophy|Disuse Atrophy (Muscle) of Lower Leg
Interventions: OTHER: Unilateral Resistance Exercise|PROCEDURE: Immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Honey to Improve Sleep Quality: a Feasibility Study
Status: COMPLETED
Conditions: Poor Quality Sleep
Interventions: DIETARY_SUPPLEMENT: Melatonin|DIETARY_SUPPLEMENT: Honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Remote Care (Questionnaire+Hybrid) in Patients Who Are Post-lung Transplant
Status: RECRUITING
Conditions: Lung Transplant; Complications
Interventions: OTHER: Hybrid care arm|OTHER: Standard of care arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acupoint Stimulation for Pain Reduction and the Associated Benefits in Head and Neck Cancer Patients Receiving Concurrent Chemoradiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: Device: Transcutaneous acupoint electrical stimulation and seeds for auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Amino Acid Uptake in Brain Tumors
Status: UNKNOWN
Conditions: Brain Neoplasms
Interventions: DRUG: O-(2-[F-18]Fluorethyl)-L-Tyrosin (FET) - PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rectal Misoprostol in Women Undergoing Myomectomy for Intraoperative Blood Loss: A Randomized Placebo-controlled Study
Status: COMPLETED
Conditions: Misoprostol, Blood Loss, Myomectomy
Interventions: DRUG: Rectal Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cost-Utility Analysis of Home-based Versus Hospital-based Chemotherapy in Multiple Myeloma: Case of Carfilzomib
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma
Interventions: OTHER: Carfilzomib delivered in OH only|OTHER: Carfilzomib delivered in OH and HaH combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oral Appliance Therapy in Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Mandibular Advancement Device (MAD)|DEVICE: nasal CPAP|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth
Status: RECRUITING
Conditions: E-cigarette Use
Interventions: OTHER: ECIG lab session 1|OTHER: ECIG lab session 2|OTHER: ECIG lab session 3|OTHER: ECIG lab session 4|OTHER: ECIG lab session 5|OTHER: ECIG lab session 6|OTHER: ECIG lab session 7|OTHER: ECIG lab session 8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Iluvien 0.19 MG Drug Implant|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Advanced or Metastatic Colorectal Cancer
Interventions: DRUG: Amivantamab|BIOLOGICAL: Fluorouracil|BIOLOGICAL: Leucovorin|BIOLOGICAL: Oxaliplatin|BIOLOGICAL: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Observational Study Confirming the Performance and Safety of the Axiom® BL X3 Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgical Operation|Edentulous Jaw|Edentulous Mouth|Implant
Interventions: DEVICE: Axiom BL X3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Behavioral Therapy (CBT) for Child Anxiety Disorders in Community Clinics in Norway
Status: COMPLETED
Conditions: Separation Anxiety Disorder|Social Phobia|Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive behavioral therapy (individual)|BEHAVIORAL: Cognitive behavioral therapy (group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Carcinoma|Refractory Bladder Carcinoma|Urinary Tract Infection
Interventions: DRUG: Clindamycin|OTHER: Diary|DRUG: Ertapenem|DRUG: Levofloxacin|DRUG: Nitrofurantoin|DRUG: Trimethoprim-Sulfamethoxazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Patches Prior to Intravenous Insertion
Status: COMPLETED
Conditions: Need for Intravenous Catheter
Interventions: DEVICE: Lidocaine tetracaine|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of ImCOOH Cream in Patients Suffering From Moderate Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: 10% ImCOOH cream|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Application Usage for Adherence of Patients Undergoing Robotic Assisted Radical Prostatectomy Following Oncological and Postoperative Functional Outcomes
Status: UNKNOWN
Conditions: the Focus of This Study is to Develop an Application for Postoperative Follow-up of Patients With Prostate Cancer
Interventions: OTHER: use of app in smartphone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Second Forward View Examination in the Right Colon
Status: COMPLETED
Conditions: Colonic Polyp|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Second forward view (SFV) examination of the right colon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Electroacupuncture Treatment for Urinary Incontinence (UI) in Women
Status: COMPLETED
Conditions: Electroacupuncture|Urinary Incontinence|Women|Pelvic Floor Muscle Weakness
Interventions: DEVICE: electroacupuncture group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decreasing the Use of Unmodified Electroconvulsive Therapy (ECT) in an Indian Hospital
Status: COMPLETED
Conditions: Major Depressive Disorder|Bipolar Disorder|Schizophrenia
Interventions: DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carvedilol 25 mg in 36 Fasted, Healthy, Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Carvedilol 25 mg tablets|DRUG: COREG® 25 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Registry of Pancreatic Fluid Collections and Pancreatic Cysts
Status: WITHDRAWN
Conditions: Pancreatic Fluid Collections|Pancreatic Cyst
Interventions: PROCEDURE: Endoscopy-based (EUS-guided) interventions for pancreatic fluid collections|PROCEDURE: EUS of pancreatic cysts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens
Status: COMPLETED
Conditions: Cataract|Presbyopia
Interventions: DEVICE: IC-8 IOL Group|DEVICE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Based-virtual Reality Diagnosis for Neuropsychiatric Diseases and Sleep/Wake Disorders
Status: UNKNOWN
Conditions: Aging|Addiction|Attention Deficit Disorder With Hyperactivity|Sleep Disorders|Anxiety|Depression|Attention Deficit
Interventions: BEHAVIORAL: Clinical interview|BEHAVIORAL: Virtual reality task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Activity of KD025 in Subjects With Chronic Graft Versus Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Belumosudil (KD025)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Early Versus Delayed Oral Feeding After Cesarean Section in Korle-bu Teaching Hospital
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: early feeding|PROCEDURE: delayed feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study in Healthy Participants and Participants With Moderate Atopic Dermatitis & Optionally, Moderate Psoriasis, and/or Mild Asthma
Status: COMPLETED
Conditions: Atopic Dermatitis|Psoriasis|Asthma
Interventions: DRUG: EDP1867|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of iLTS-D® and ILMA® for Intubation With Fiberoptic Control
Status: UNKNOWN
Conditions: Intubation; Difficult
Interventions: DEVICE: Intubation through ILMA®|DEVICE: Intubation through ILTS®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Trial of Temozolomide, Bevacizumab Plus Bortezomib for Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Temozolomide, bevacizumab and bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Experiences as Tools to Support Mental Health in Parents of Children With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Parents
Interventions: OTHER: Virtual Reality-mediated Mindfulness-Based Interventions|OTHER: Virtual Reality-mediated Mindfulness-Based Interventions without audio guided experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OPTImal CArdiac REhabilitation (OPTICARE) Following Acute Coronary Syndromes
Status: COMPLETED
Conditions: Risk Reduction Behavior|Life Style
Interventions: OTHER: rehabilitation+telephonic coaching|OTHER: OPTICARE-B|OTHER: OPTICARE-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discontinuing Inappropriate Medication in Nursing Home Residents
Status: COMPLETED
Conditions: Polypharmacy Because of Multimorbidity in Geriatric Nursing Home Residents
Interventions: PROCEDURE: Multidisciplinary medication review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IMU-935 in Patients With Progressive, Metastatic Castration Resistant Prostate Cancer
Status: TERMINATED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: IMU-935
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Early Vs Delayed Feeding on Rebleeding Following Endoscopic Ligation for Acute Esophageal Variceal Bleeding
Status: COMPLETED
Conditions: Acute Gastroesophageal Variceal Bleeding
Interventions: OTHER: Early refeeding group|OTHER: Delayed refeeding group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a PF Ophthalmic Solution Containing HA0.4% and TAU 0.5%
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Hyaluronic acid 0.4% and Taurine 0.5%|DEVICE: Hyaluronic acid 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can a Rapid 2 Day Followup After Discharge From the ED Reduce Readmissions and Death for Patients 75 Years and Older?
Status: COMPLETED
Conditions: Emergencies
Interventions: OTHER: 2-3 day return appointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tirofiban for the Prevention of Neurological Deterioration in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Stroke
Interventions: DRUG: Tirofiban Hydrochloride|DRUG: Oral antiplatelet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of TQ-A3334 Tablet After Multiple Administration in Adult Subjects
Status: RECRUITING
Conditions: Hepatitis B
Interventions: DRUG: TQ-A3334 tablets|DRUG: TQ-A3334 placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Causal Relationships Between LC-omega-3-enriched Diet and Cognition
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: omega-3 fatty acid supplementation|DIETARY_SUPPLEMENT: corn/soybean oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of ABT-263 as Single Agent in Women With Platinum Resistant/Refractory Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Platinum-resistant or Refractory Ovarian Cancer
Interventions: DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation With Targeted Busulfan and Fludarabine in Pediatric AML
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon
Status: WITHDRAWN
Conditions: Huntington's Disease|Parkinson's Disease|Dementia With Lewy Bodies|Sleep Disorders|Circadian Dysregulation
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Polatuzumab, Bendamustine and Rituximab in Patients With Relapsed/ Refractory Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle-cell Lymphoma
Interventions: DRUG: Polatuzumab, bendamustin und rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)
Status: RECRUITING
Conditions: Hepatic Encephalopathy|Acute-On-Chronic Liver Failure
Interventions: DRUG: Branch Chain Amino Acid|DRUG: Lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Status: WITHDRAWN
Conditions: Disruptive Mood Dysregulation Disorder|Attention Deficit Hyperactivity Disorder|Normal Physiology
Interventions: BEHAVIORAL: Affective Posner fMRI frustration induction task
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Chemotherapy Based on CA 125 Level Alone Compared With Delayed Chemotherapy in Treating Patients With Recurrent Ovarian Epithelial , Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Transdermal Testosterone Patches in Menopausal Women With Low Libido
Status: COMPLETED
Conditions: Hypoactive Sexual Desire Disorder
Interventions: DRUG: Testosterone (transdermal patches)|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Leiomyoma|Menorrhagia|Metrorrhagia
Interventions: DRUG: Asoprisnil|DRUG: Asoprisnil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Over Active Bladder Instillation Study - Botox
Status: TERMINATED
Conditions: Overactive Bladder|Urinary Urge Incontinence|Urinary Incontinence|Detrusor Hyperreflexia|Urge Incontinence
Interventions: DRUG: Botox Instillation|DRUG: DMSO Instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant Recipients
Status: WITHDRAWN
Conditions: Cardiac Allograft Vasculopathy
Interventions: DRUG: Sirolimus|DRUG: Sirolimus|DRUG: Sirolimus|DRUG: Sirolimus|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Labour Induction With Misoprostol, Dinoprostone and Bard Catheter
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: misoprostol|DRUG: dinoprostone|DEVICE: Bard Catheter (balloon catheter)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of CBCT to Improve Inferior Alveolar Nerve Block Success
Status: COMPLETED
Conditions: Inferior Alveolar Nerve|Mandibular Nerve Blocks
Interventions: DRUG: 2% Lidocaine with 1:100,000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunologic Effects of Echinacea
Status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Interventions: BIOLOGICAL: Echinacea purpurea|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: [68Ga]Ga-NeoB|DRUG: [177Lu]Lu-NeoB|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Amuvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Alcohol Abuse|Alcohol Dependence|Alcohol-Related Disorders|Drug Abuse|Substance Use Disorders|Mental Disorder
Interventions: DEVICE: Active transcranial Direct Current Stimulation|DEVICE: Sham transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SMART Design to Compare Antipsychotic Treatments in Treatment-Resistant Schizophrenia
Status: UNKNOWN
Conditions: Treatment-resistant Schizophrenia
Interventions: DRUG: Clozapine|DEVICE: MECT|DEVICE: DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Diabetic Gastroparesis
Status: SUSPENDED
Conditions: Diabetic Gastroparesis
Interventions: OTHER: Acupuncture|PROCEDURE: placebo/sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of GT90001 and Nivolumab in Patients With Metastatic Hepatocellular Carcinoma(HCC)
Status: COMPLETED
Conditions: Metastatic Hepatocellular Carcinoma|HCC|Combinations of Drugs; Dependence
Interventions: DRUG: GT90001 and Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Custodiol-HTK (Histidine-tryptophan-ketoglutarate) Solution as a Cardioplegic Agent
Status: COMPLETED
Conditions: Coronary Artery Disease|Myocardial Ischemia|Coronary Disease|Heart Diseases|Valvular Heart Disease
Interventions: DRUG: Custodiol HTK|DRUG: Cold Blood Cardioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technique to Measure Type C Fibre Nerve Conduction Velocitynerve Fibers in Polyneuropathies
Status: COMPLETED
Conditions: Peripheral Nervous System Diseases
Interventions: DIAGNOSTIC_TEST: Sympathetic skin response (SSR) measure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
Status: RECRUITING
Conditions: Panhypopituitarism|Gigantism/Acromegaly|Prolactinoma|Cushing Disease
Interventions: PROCEDURE: MRI|PROCEDURE: Tissue specimen collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2)
Status: COMPLETED
Conditions: Polycystic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Niacinamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electrical Acupoint Stimulation Reduces Intrathecal Anesthesia Induced Hypotension
Status: COMPLETED
Conditions: Hypotension During Surgery
Interventions: OTHER: high frequency acupoint stimulation|OTHER: low frequency acupoint stimulation|OTHER: electrodes attached
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Losartan on the Recoverability of Renal Function in Anuric and Oliguric Patients With Unilateral Obstructed Kidney
Status: COMPLETED
Conditions: Losartan Adverse Reaction|Uropathy|Uropathy Obstructive
Interventions: DRUG: Cozaar (Losartan Potassium 25mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Interventions for Leg Ulcer Patients
Status: COMPLETED
Conditions: Leg Ulcers|Venous Ulcers|Varicose Ulcers
Interventions: DEVICE: FOOTFIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: D-Cycloserine as an Adjunct to Internet-CBT for OCD
Status: COMPLETED
Conditions: Obsessive-compulsive Disorder
Interventions: DRUG: D-Cycloserine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blue Wavelength Light-blocking Glasses in ADHD-Insomnia
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Delayed Sleep Phase Type Circadian Rhythm Sleep Disorder
Interventions: DEVICE: Polarized glasses designed to filter out blue light
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effective Treatment for Prescription Opioid Abuse
Status: COMPLETED
Conditions: Prescription Opioid Dependence
Interventions: DRUG: buprenorphine taper followed by naltrexone maintenance|BEHAVIORAL: Behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Ropivacaine|DRUG: 0.9% Nacl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Retinal and Vascular Features in Radiation Maculopathy After Intravitreal Injections of Ranibizumab
Status: COMPLETED
Conditions: Radiation Maculopathy
Interventions: DRUG: Ranibizumab 0.5Mg/0.05Ml Oph Inj
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Effectiveness of IMC-A12 Antibody Combined With Hormone Therapy Prior to Surgery to Treat Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: IMC-A12|DRUG: Bicalutamide|DRUG: Goserelin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: Sulbactam-ETX2514|DRUG: Placebo|DRUG: Imipenem-cilastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Corticosteroid Withdrawal in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium inhalation|DRUG: salmeterol xinafoate|DRUG: fluticasone propionate|DRUG: placebo matched for fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KN046 in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: KN046|RADIATION: palliative radiotherapy|DRUG: KN046
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Paracetamol and Ibuprofen Reducing Morphine Requirements After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Paracetamol injection and Ibuprofen injection|DRUG: Paracetamol injection and normal saline|DRUG: Ibuprofen Injection and normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leukemia SPORE Phase II DAC Study for R/R and Elderly Acute AML and MDS
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia
Interventions: DRUG: Decitabine|DRUG: Carboplatin|DRUG: Arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Cognitive Therapy in a Clinical Sample of OCD Patients
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy (MBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab (LY3650150) in Adult Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Interventions: DRUG: LY3650150|DRUG: Placebo|DRUG: Standard therapy for INCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Therapy With Anti-TNFα vs Cyclophosphamide in Severe Behçet Disease
Status: COMPLETED
Conditions: Behcet's Disease|Vasculitis
Interventions: DRUG: Infliximab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised, Double-blind, Placebo-controlled Study of Topical Clobetasone Butyrate 0.05% Cream in Subjects With Eczema for Two Weeks to Evaluate the Efficacy and Safety
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: Clobetasone Butyrate 0.05% Cream|DRUG: Vehicle (base cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET®
Status: COMPLETED
Conditions: Food Sensitivities|Headache|Backache|Indigestion|Eczema, Acne, Hives and Itching of the Skin
Interventions: PROCEDURE: NAET Procedures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Non-Nutritive Sucking vs Non-Nutritive Sucking Combined With Breast Milk on the Neonatal Comfort
Status: COMPLETED
Conditions: Infant, Premature
Interventions: PROCEDURE: Only NNS|PROCEDURE: NNS Combined with Breast Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Increasing Screening for Cancer Using EHR-Nudges
Status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Post-visit patient text messaging|BEHAVIORAL: Default pended order|BEHAVIORAL: High risk bidirectional post-visit text messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia
Status: UNKNOWN
Conditions: Sedentary Behavior|Hypertriglyceridemia
Interventions: BEHAVIORAL: Interrupting Prolonged Sitting with Periodic Interval Exercise: Effect on Postprandial Lipemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LEft Atrial Pacing in Diastolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Atrial Dyssynchrony Syndrome|Left Atrio-ventricular Asynchrony
Interventions: PROCEDURE: pace make active/inactive cross over
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.
Status: RECRUITING
Conditions: Hypertension|Diabetes Mellitus|Blood Disease
Interventions: BIOLOGICAL: rhBMP-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Altruistic Decisions
Status: TERMINATED
Conditions: Healthy
Interventions: OTHER: Behavior|OTHER: fMRI (functional Magnetic Resonance Imagery)|OTHER: MEG (MagnetoEncephaloGraphy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety, Tolerability, MTD, PK, and Activity of Oraxol in Subjects w Adv. Malignancies
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Oraxol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult|Metastatic Solid Tumor|Refractory Cancer
Interventions: DRUG: ADU-1805|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
Status: RECRUITING
Conditions: Emphysema or COPD
Interventions: PROCEDURE: Interlobar fissure completion and pleural adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance and Pharmacokinetics of Anidulafungin in Immunocompromised Children Ages 2-17
Status: COMPLETED
Conditions: Neutropenia
Interventions: DRUG: Anidulafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micropulse for Suppression of Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Micropulse Laser Treatment|DEVICE: Sham Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Stapled Antimesenteric Anastomosis for CD: a Randomized Control Trial Study
Status: RECRUITING
Conditions: Crohn Disease|Recurrence
Interventions: PROCEDURE: Kono-S group|PROCEDURE: Side-to-side group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
Status: RECRUITING
Conditions: Post-traumatic; Arthrosis|Tibial Fractures|Post-Traumatic Osteoarthritis of Ankle
Interventions: PROCEDURE: Joint Lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: VIR-7831|BIOLOGICAL: Placebo|BIOLOGICAL: Remdesivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin as a Modulator of Systemic Vascular Resistance and Cardiac Output in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2 (T2DM)
Interventions: DRUG: Empagliflozin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of Mentalization Profiles Related to Emotional Regulation Among Teenagers With Behavioral Disorders
Status: NOT_YET_RECRUITING
Conditions: Adolescent Behavior Disorder|Eye Movements
Interventions: BEHAVIORAL: Mentalisation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Umbilical Cord Milking in the Management of Hypoxic-ischemic Encephalopathy in Neonates
Status: UNKNOWN
Conditions: Hypoxic-Ischemic Encephalopathy
Interventions: PROCEDURE: Umbilical Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide and Dacarbazine (DTIC) in Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Lenalidomide|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Appendectomy Surgeries
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: M-TAPA block with bupivacaine 25%|OTHER: TAP block with bupivacaine 25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of EndoRefix Endovascular Delivery System and Staple
Status: WITHDRAWN
Conditions: AAA Graft Implant for Primary Aneurysm Treatment|AAA Graft Repair to Extend Life of Implant
Interventions: DEVICE: EndoRefix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Hypoxia-Stressed Bone Marrow Mononuclear Cell Transplantation to Treat Heart Diseases
Status: UNKNOWN
Conditions: Myocardial Infarction (MI) or Acute Myocardial Infarction (AMI)
Interventions: PROCEDURE: Hypoxia-stressed BMSCs transplantation to cure MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Zolpidem Tartrate Sublingual Tablet in Adult Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: zolpidem tartrate sublingual tablet 3.5mg|DRUG: zolpidem tartrate sublingual tablet 1.75mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine For Suicidal Ideation
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The European Cobalt STent With Antiproliferative for Restenosis Trial (EuroSTAR Trial)
Status: COMPLETED
Conditions: Treatment of Symptomatic Ischemic Heart Disease
Interventions: DEVICE: Conor Medsystems COSTAR™ stent (10 µg Paclitaxel)|DEVICE: Conor Medsystems COSTAR™ stent (30 µg Paclitaxel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auricular Pressure for Postoperative Pain After Hemorrhoidectiomy: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: OTHER: Auricular pressure|OTHER: Shame auricular pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma
Status: NOT_YET_RECRUITING
Conditions: High Grade Glioma|MGMT-Unmethylated Glioblastoma|MGMT-Methylated Glioblastoma
Interventions: GENETIC: DB107-RRV|GENETIC: DB107-FC|RADIATION: Radiation Therapy (RT)|DRUG: Temozolomide|PROCEDURE: Magnetic Resonance Imaging (MRI)|PROCEDURE: Surgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controls for Respiratory Diseases
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Asthma|Idiopathic Pulmonary Fibrosis|Nontuberculous Mycobacterium Infection|Bronchiectasis|Lung Cancer
Interventions: OTHER: no intervation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Pharmacokinetics and Safety of Singulair and Xyzal in Free Combination and Fixed-dose Combination
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: HCP1102|DRUG: Singulair and Xyzal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Quality of Recovery After Cesarean Section Surgery
Status: COMPLETED
Conditions: Postoperative Recovery|Abdominal Pain|Cesarean Section
Interventions: PROCEDURE: Transversalis Fascia Plane Block|PROCEDURE: Transversus Abdominis Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Investigate Fenoldopam Usage in the Prevention of Postoperative Renal Dysfunction in Patients at a High Risk for Renal Impairment During Cariopulmonary Bypass for Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery With Cardiopulmonary Bypass
Interventions: DRUG: Fenoldopam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Arabinoxylan Rice Bran (MGN-3/Biobran) for the Treatment of Hepatocellular Carcinoma and Hepatitis B and C Infection
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatitis B
Interventions: PROCEDURE: PEIT|PROCEDURE: TOCE|PROCEDURE: TOCE plus PEIT|PROCEDURE: TOCE plus RFA|DIETARY_SUPPLEMENT: MGN-3|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Dietary Intervention on Intracellular Lipid Levels, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes
Status: SUSPENDED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma|Metastatic Pancreatic Cancer
Interventions: DRUG: Nab-Paclitaxel|DRUG: Gemcitabine|DRUG: Indoximod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrapartum Glucose and Insulin Compared to Glucose Alone in Diabetic Women
Status: RECRUITING
Conditions: Obstetric Labor|Pregnancy in Diabetics
Interventions: DRUG: glucose solution and Insulin|DRUG: glucose solution only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zanubrutinib and G-CHOP in Untreated Intermediate-high Risk Follicular Lymphoma
Status: NOT_YET_RECRUITING
Conditions: FL
Interventions: DRUG: Zanubrutinib|DRUG: Obinutuzumab|DRUG: Prednisone|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT