pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: H5N1 Vaccine Study in Japanese Elderly Population Aged 65 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H5N1 Influenza Vaccine (Whole Virion, Vero Cell-Derived, Inactivated), non-adjuvanted formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Adenovirus Serotype 26.Respiratory Syncytial Virus.Pre-Fusion F (Ad26.RSV.preF)-Based Vaccine for Prevention of Respiratory Syncytial Virus (RSV) Mediated- Lower Respiratory Tract Disease (LRTD) in Japanese Participants
Status: TERMINATED
Conditions: Respiratory Syncytial Virus Prevention
Interventions: BIOLOGICAL: Ad26/protein preF RSV Vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Empaglifozin and Vildagliptin in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Empagliflozin|DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction in Sensitized Kidney Transplant Recipients Without Pre-existing Donor-specific antiboDies
Status: NOT_YET_RECRUITING
Conditions: Renal Transplant Rejection|Induction Therapy
Interventions: DRUG: Rabbit Anti thymocyte globulin (rATG)|DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisolone +/- Addition of Anti-CD20 Antibody, Rituximab, in Patients With Immune Hemolytic Anemia
Status: COMPLETED
Conditions: Anemia, Hemolytic, Autoimmune
Interventions: DRUG: prednisolone + mabthera|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usefulness Of Flospan As A Premedication For Colonoscopy
Status: UNKNOWN
Conditions: Colonoscopy
Interventions: DRUG: Phloroglucin|DRUG: Cimetropium bromide|PROCEDURE: Colonoscopy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of COLAL-PRED to Treat Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Placebo|DRUG: COLAL-PRED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Fixed-bearing Versus Mobile-bearing Prosthesis in Total Knee Arthroplasty: A Prospective Randomized Trial
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: fixed-bearing (P.F.C.® Sigma)|DEVICE: mobile-bearing (P.F.C.® Sigma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Intervention Effect of Self-help Training Camps in Promoting Mental Health Among Perinatal Women
Status: NOT_YET_RECRUITING
Conditions: Mental Health|Perinatal Depression
Interventions: COMBINATION_PRODUCT: Mental Fitness Training Camp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolomic and Inflammatory Effects of Oral Aspirin (ASA) in Subjects at Risk for Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: Aspirin 81 mg|DRUG: Aspirin 325mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Compative Study of PE in Thrombosed AVF After Balloon Thrombectomy vs. Thromboaspiration.
Status: RECRUITING
Conditions: Pulmonary Embolism and Thrombosis
Interventions: DEVICE: Balloon thrombectomy|DEVICE: Thromboaspiration system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: FiO2 and Outcomes After Cardiac Surgery With Cardiopulmonary Bypass
Status: WITHDRAWN
Conditions: Patients Undergoing Cardiac Surgery Using Cardiopulmonary Bypass
Interventions: OTHER: Fraction of inspired oxygen level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Olanzapine, Netupitant and Palonosetron in Controlling Nausea and Vomiting Associated With Highly Emetogenic Chemotherapy in Patients With Breast Cancer
Status: COMPLETED
Conditions: Nausea Post Chemotherapy
Interventions: DRUG: Olanzapine|DRUG: Netupitant|DRUG: Palonesetron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VALENCE: Valsartan Versus Atenolol on Exercise Capacity in Hypertensive Overweight Postmenopausal Women
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan|DRUG: atenolol|DRUG: hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Tear|Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture
Interventions: DRUG: Intraosseous Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brazilian inteRvention to Increase eviDence usaGe in practicE - Cardiovascular Prevention
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Quality Improvement Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Lung Volume Reduction After Catheter-based CV Measurement in Patients With Heterogeneous Emphysema and Complete Interlobar Fissures
Status: UNKNOWN
Conditions: Heterogeneous Emphysema
Interventions: DEVICE: Implantation of valves (IBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Ciprofloxacin (BAYQ3939) dry powder for inhalation|DRUG: Ciprofloxacin (BAYQ3939) dry powder for inhalation|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery
Status: TERMINATED
Conditions: Cervical Radiculopathy|Cervical Disc Disease
Interventions: DEVICE: Spira-C Interbody Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease
Status: TERMINATED
Conditions: Arrhythmia
Interventions: DRUG: GAP-486 (ZP-123)|DRUG: 0.9% Sodium Chloride, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Xolair|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
Status: RECRUITING
Conditions: Lipodystrophy|Diabetes|Hyperlipidemia
Interventions: DRUG: Metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects
Status: COMPLETED
Conditions: Migraine With Aura|Migraine Without Aura|Migraine
Interventions: DRUG: Dihydroergotamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Trials for Stress Management Against Standard of Care
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Personalized Trial ABCCBA|BEHAVIORAL: Personalized Trial CBAABC|BEHAVIORAL: Stress Management Techniques with No Randomization Sequence (or order)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase III Clinical Study of KW-2246 for Breakthrough Pain in Cancer Patients
Status: COMPLETED
Conditions: Pain, Cancer
Interventions: DRUG: Placebo|DRUG: KW-2246 (fentanyl citrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Mandala on Nausea, Vomiting, Pain and Anxiety in Chemotherapy Patients
Status: RECRUITING
Conditions: Pain|Anxiety
Interventions: BEHAVIORAL: Mandala group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms
Status: COMPLETED
Conditions: Postpartum Depression|Parenting|Parent-Child Relations
Interventions: BEHAVIORAL: Social Media-Based Parenting Program|BEHAVIORAL: MoodGym
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors Influencing Hepatitis B Virus Reactivation in Lymphoma Patients Treated With Rituximab
Status: COMPLETED
Conditions: Patients With Diffuse Large B-cell Lymphoma or Follicular Lymphoma|Patients Treated With Rituximab-CHOP or Rituximab-CVP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Creatine Monohydrate on Persistent Post-concussive Symptoms
Status: RECRUITING
Conditions: Mild Traumatic Brain Injury|Concussion, Brain
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vigiis 101-LAB on a Healthy Populations' Gut Microflora, Peristalsis, Immunity, and Anti-oxidative Capacity
Status: COMPLETED
Conditions: Gastrointestinal Microbiome
Interventions: DIETARY_SUPPLEMENT: Vigiis 101-LAB|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: the Clinical Efficacy of Robotic and Laparoscopic Radical Total Gastrectomy in Locally Advanced Middle and Upper Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer|Robotic Gastrectomy
Interventions: PROCEDURE: Robotic radical total gastrectomy with D2 lymphadenectomy|PROCEDURE: Laparoscopic radical total gastrectomy with D2 lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Dupilumab|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: accelerated partial breast irradiation - 3D-conformal planning|RADIATION: accelerated partial breast irradiation - IMRT planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Neuroblastoma|Refractory Neuroblastoma|Relapsed Osteosarcoma|Relapsed Ewing Sarcoma|Relapsed Rhabdomyosarcoma|Uveal Melanoma|Phyllodes Breast Tumor
Interventions: GENETIC: C7R-GD2.CART cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bone Marrow Transplantation Using Fully-Matched Relatives as Donors for Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Hematological Malignancies|Leukemia|Lymphoma|Multiple Myeloma|Hodgkin's Disease
Interventions: DEVICE: Matched Sibling Allogeneic Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Into Genetic Influence on Cholesterol Response to Dietary Fat
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Low fat diet|DIETARY_SUPPLEMENT: Hgih saturated fat diet|DIETARY_SUPPLEMENT: High saturated fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Methodologies for Observational Studies Comparing Inpatient COVID-19 Treatments
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Initiation of IL6Ri (tocilizumab or sarilumab) versus JAKi (baricitinib or tofacitinib) added to systemic corticosteroids of interest (CSI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dapagliflozin and Hydrochlorothiazide in Recurring Kidney Stone Patients
Status: NOT_YET_RECRUITING
Conditions: Urolithiasis|Hyperoxaluria
Interventions: DRUG: Dapagliflozin|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Co2 Laser Versus Co2 Laser With PRP in Scars
Status: COMPLETED
Conditions: CO2 Laser in Scars
Interventions: PROCEDURE: Fractional CO2 laser|PROCEDURE: Fractional CO2 with Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of an Exercise Intervention for Children With Haemophilia
Status: RECRUITING
Conditions: Hemophilia|Child, Only|Musculoskeletal Diseases or Conditions
Interventions: OTHER: Exercise|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second-line Therapy Study of Combined Chemotherapy and Endostar to Patients With Non-Small Cell Lung Cancer(NSCLC)
Status: UNKNOWN
Conditions: Advanced NSCLC|Recurrent NSCLC
Interventions: DRUG: Endostar(rh recombinant endostatin) plus Docetaxel|DRUG: Placebo plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia
Status: UNKNOWN
Conditions: Community Acquired Pneumonia
Interventions: DRUG: Faropenem|DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Suubi4Stigma: Addressing HIV-Associated Stigma Among Adolescents
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy (G-CBT)|BEHAVIORAL: Multiple Family Group (MFG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0213 Chemotherapy Plus Rituximab in Treating Patients With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: doxorubicin|DRUG: leucovorin|DRUG: methotrexate|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARIADNE: A Study of Weight Loss for Diabetes Treatment and Wellbeing
Status: ACTIVE_NOT_RECRUITING
Conditions: Type2diabetes|Disordered Eating|Obesity|Overweight and Obesity|Diet Habit
Interventions: BEHAVIORAL: Low calorie total diet replacement|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of NVP-1203 in Patients With Acute Low Back Pain
Status: COMPLETED
Conditions: Acute Low Back Pain
Interventions: DRUG: NVP-1203|DRUG: NVP-1203-R|DRUG: NVP-1203 placebo|DRUG: NVP-1203-R placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreatic Carcinoma Non-resectable|Locally Advanced Malignant Neoplasm
Interventions: DRUG: FOLFIRINOX|BIOLOGICAL: Algenpantucel-L Immunotherapy|RADIATION: 5-FU Chemoradiation|DRUG: Gemcitabine|DRUG: Capecitabine|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of the Submucosal Conchoplasty Technique in Improving the Postoperative Middle Meatus Outcome After ESS
Status: COMPLETED
Conditions: Endoscopic Sinus Surgery
Interventions: PROCEDURE: submucosal conchoplasty|PROCEDURE: classic lateral lamellectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Mixed-methods Evaluation of an Adapted Acceptance and Commitment Therapy (ACT) Group for Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Acceptance and Commitment Therapy
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline Augmentation of Clozapine for Treatment Resistant Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Building Community Capacity for Disability Prevention for Minority Elders (Positive Minds - Strong Bodies)
Status: COMPLETED
Conditions: Depression|Anxiety|Physical Disability
Interventions: BEHAVIORAL: Comparison of a combined CBT + exercise intervention and enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optimum Length of Catheter in the Epidural Space for Labor Analgesia in Non-obese Women: a Randomised Controlled Trial of 4 cm Versus 5 cm
Status: RECRUITING
Conditions: Labor Pain
Interventions: OTHER: Epidural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Immunogenicity of a U.S.-Licensed Meningococcal Serogroup B Vaccine (Trumenba)
Status: COMPLETED
Conditions: Meningococcal Infections
Interventions: BIOLOGICAL: Trumenba Vaccine (Wyeth/Pfizer Pharmaceuticals)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies
Status: WITHDRAWN
Conditions: Allergy|Allergic Asthma|Allergy to Cats|Allergy to House Dust|Allergy to Dog Dander|Allergy Cockroach
Interventions: DEVICE: Blood Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Percutaneous High Frequency Alternating Current Stimulation in Healthy Volunteers With 30kHz
Status: COMPLETED
Conditions: Electrical Stimulation|Neuromodulation
Interventions: DEVICE: 30 kHz stimulation (Myomed 932, Enraf-Nonius)|DEVICE: Sham stimulation (Myomed 932, Enraf-Nonius)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in the Acute Treatment of Adults With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Leukotriene Receptor Antagonists in Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Happy Mother-Healthy Baby: An Anxiety-focused Early Prenatal Intervention
Status: COMPLETED
Conditions: Postpartum Depression|Small for Gestational Age at Delivery|Preterm Birth|Anxiety|Birth Weight
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy Intervention for Anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Therapeutic Alliance in the Rehabilitation of Knee Osteoarthritis.
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Enhanced TA|OTHER: Limited TA|OTHER: Therapeutic exercise protocol.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose Escalation of Single Fraction Adjuvant Stereotactic Body Partial Breast Irradiation Early Stage Breast CA
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Stage Breast Cancer
Interventions: RADIATION: Stereotactic Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of Simotinib Hydrochloride in Patients With Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Simotinib Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Diabetic Nephropathy With Atrasentan
Status: TERMINATED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Atrasentan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endometrial Safety of a Low Dose of Vagifem® in Postmenopausal Women With Atrophic Vaginitis
Status: COMPLETED
Conditions: Menopause|Postmenopausal Vaginal Atrophy
Interventions: DRUG: estradiol, 10 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRAF Inhibitor, Vemurafenib, in Patients With Relapsed or Refractory Hairy Cell Leukemia
Status: COMPLETED
Conditions: Hairy Cell Leukemia
Interventions: DRUG: Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic in Total Knee Arthroplasty (TKA): Volume Versus Concentration
Status: COMPLETED
Conditions: Postoperative Pain|Analgesic Efficacy
Interventions: DRUG: 20 mL ropivacaine 5 mg/mL|DRUG: 10 mL ropivacaine 10 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective and Cardioprotective Effects Of Palm Vitamin E Tocotrienols
Status: COMPLETED
Conditions: Cerebrovascular Disorders
Interventions: DIETARY_SUPPLEMENT: 200mg of Palm vitamin E (tocotrienols) or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Volume Foleys Increasing Vaginal Birth Pilot Trial
Status: UNKNOWN
Conditions: Labour; Induced|Pilot Study|Cervical Ripening
Interventions: DEVICE: Foley catheter filled to 80cc|DRUG: prostaglandin of the clinician's choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: AK102|DRUG: Placebos|DRUG: Statins and/or Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trident Landmark as a Safe and Easy Method for Facial Nerve Trunk Identification During Superficial Parotidectomy
Status: COMPLETED
Conditions: Parotid Tumor|Parotid Neoplasms|Surgery|Head and Neck Disorder
Interventions: PROCEDURE: Superficial parotidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Pilot Study Evaluating Dental Side Effects of Radiotherapy on Subjects Treated for Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: PROCEDURE: Dental avulsion|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Audio for Anaesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: Brain.fm Music|OTHER: Spectrally-matched Noise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimizing Dementia Care
Status: COMPLETED
Conditions: Alzheimer's Disease|Dementia|Dementia, Vascular|Caregivers|Veterans
Interventions: BEHAVIORAL: Counseling (C)|BEHAVIORAL: Care Consultation (CC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Cell Therapy for Stress Urinary Incontinence in Males Following Prostate Surgery
Status: COMPLETED
Conditions: Urinary Incontinence|Stress|Urination Disorders|Urologic Diseases|Lower Urinary Tract Symptoms|Urological Manifestations
Interventions: BIOLOGICAL: autologous muscle-derived cells (AMDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEVOSIMENDAN to Facilitate Weaning From ECMO in Severe Cardiogenic Shock Patients
Status: RECRUITING
Conditions: Cardiogenic Shock|Extracorporeal Membrane Oxygenation Complication
Interventions: DRUG: Levosimendan|DRUG: Placebo of Levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Versus Double Dose Intra-vaginal Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy
Status: COMPLETED
Conditions: Prostaglandin E2 "Misoprostol" Prior Abdominal Myomectomy
Interventions: DRUG: 2 doses 400 microgram misoprostol|DRUG: single dose misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Expanded Access Protocol of ATA230 (Third-Party Donor-Derived CMV-CTLs) for the Treatment of CMV Viremia or Disease
Status: NO_LONGER_AVAILABLE
Conditions: CMV Viremia|CMV Disease
Interventions: BIOLOGICAL: Cytomegalovirus-specific Cytotoxic T Lymphocytes (CMV-CTLs)
Study Type: EXPANDED_ACCESS
Clinical trial: Evaluate Safety and Tolerability of Calcipotriene Foam 0.005% in Pediatric Subjects With Mild/Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Calcipotriene 0.005% Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pseudovitellium Detachment With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
Status: COMPLETED
Conditions: Pseudovitellium Detachment|Eye Diseases
Interventions: DRUG: Anecortave Acetate Sterile Suspension (15 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir in Treatment-Naïve Hepatitis C Virus Genotype 1b-Infected Adults
Status: COMPLETED
Conditions: Hepatitis C Infection|Hepatitis C Virus
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir|DRUG: dasabuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL
Status: UNKNOWN
Conditions: Postoperative Cognitive Dysfunction|NEURON SPECIFIC ENOLASE|MINI MENTAL STATE EXAMINATION TEST
Interventions: BEHAVIORAL: POSTOPERATIVE COGNITIVE DYSFUNCTION
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acalabrutinib and Duvelisib for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Recurrent Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Nodal Marginal Zone Lymphoma|Recurrent Splenic Marginal Zone Lymphoma|Refractory Follicular Lymphoma|Refractory Indolent Non-Hodgkin Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Nodal Marginal Zone Lymphoma|Refractory Splenic Marginal Zone Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Dose-escalation Study of a Combination of Pazopanib and Bevacizumab in Patients With Metastatic Renal Cell Carcinoma or Others Advanced Solid Tumors
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma|Advanced Refractory Solid Tumors Histologically or Cytologically Confirmed
Interventions: DRUG: Association of Bevacizumab (BVC)+ Pazopanib (PZP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary FIbrinolysis and Secondary STenting Versus immEdiate Stenting in ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Ischemia|Acute Coronary Syndrome|Heart Diseases|Syndrome Heart Disease|Cardiovascular Diseases|Arteriosclerosis|Arterial Occlusive Diseases|Coronary Disease|Vascular Diseases
Interventions: PROCEDURE: immediate stenting group(one-step strategy)|PROCEDURE: deferred stenting group (two-step strategy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effects of Modified TRS Treatment
Status: UNKNOWN
Conditions: Tinnitus, Subjective
Interventions: OTHER: Listening to unmodified music|OTHER: Listening to modified tinnitus relieving sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol Injection Phase II Trial
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: paricalcitol|DRUG: paricalcitol|DRUG: paricalcitol|DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Liraglutide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dry Eye OmniLenz Application of Omnigen Research Study
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: Amniotic membrane Omnigen[TM]|DEVICE: Bandage soft Contact Lens OmniLenz[R]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Noninvasive Brain Stimulation Techniques on BDNF Levels
Status: UNKNOWN
Conditions: Depression|Schizophrenia
Interventions: DEVICE: non invasive brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of BMS-650032 With Peginterferon Alfa-2a Plus Ribavirin
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: DRUG: BMS-650032|DRUG: BMS-650032|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Peginterferon Alfa-2a|DRUG: Peginterferon Alfa-2a|DRUG: Ribavirin|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Dose-Related Efficacy and Safety of PS433540 in Subjects With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: irbesartan|DRUG: placebo|DRUG: PS433540|DRUG: PS433540|DRUG: PS433540
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Performance Characteristics of Mesofiller Mesotox for the Correction of Wrinkles and Rehydration of the Face.
Status: COMPLETED
Conditions: Skin Aging|Skin Wrinkling
Interventions: DEVICE: mesofiller® mesotox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Mono-center, Interventional Study Evaluating the Effect of One Year Initial Care by Hygieno-dietary Advices With or Without Phlebotomy on Glycemia After at Least 5 Years in Patients With Dysmetabolic Iron Overload Syndrome
Status: COMPLETED
Conditions: Dysmetabolic Iron Overload Syndrome
Interventions: OTHER: Oral Glucose Tolerance Test (OGTT)|OTHER: Clinical exam|BIOLOGICAL: Blood sample|DEVICE: MRI|DEVICE: Bioimpedance|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study of F14 for Management of Pain Following Total Knee Replacement
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: F14|DRUG: 0.25 % Bupivacaine HCl|DRUG: Acetaminophen|DRUG: Methocarbamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Heat Versus Sitz Bath On Episiotomy Wound Heating And Pelvic Pain
Status: COMPLETED
Conditions: Wound Heal|Pain, Postoperative
Interventions: RADIATION: Dry Heat Application|OTHER: Moist Heat Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Status: COMPLETED
Conditions: Hypertension With Complications and Secondary Hypertension|Overweight and Obesity|Lipid Metabolism Disorders|Sarcopenia|Osteoporosis|Personal Satisfaction
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Immunosuppressive Therapy With Certican (Everolimus) After Lung Transplantation
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DRUG: Everolimus|DRUG: Mycophenolatmofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Strategy for Asymptomatic Sexually Transmitted Infections (STI) in a Cohort of HIV Outpatients Men Who Have Sex With Men (DRIVER)
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: creation of a STIs score risk|OTHER: validation of a STIs score risk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Gene Expression and DNA Variation Analysis of Sacs to Identify the Pathophysiology of Indirect Inguinal Hernia
Status: UNKNOWN
Conditions: Indirect Inguinal Hernia|Genetic Predisposition to Disease
Interventions: GENETIC: mRNA expression and SNP analysis|DIAGNOSTIC_TEST: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anfibatide Phase 1 Clinical Trial in Healthy Volunteers
Status: COMPLETED
Conditions: Coronary Heart Disease|Coagulation Disorder
Interventions: DRUG: Anfibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Vaccine and Interferon Gamma in Treating Patients With Refractory Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Epithelial Cancer
Interventions: BIOLOGICAL: ALVAC-hB7.1|BIOLOGICAL: recombinant interferon gamma|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Status: TERMINATED
Conditions: Acute Myeloid Leukemia, Relapsed, Adult
Interventions: DRUG: F16IL2|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy of Administration of Cyclosporine (Low Dose and High Dose) and Prednisolone Acetate Compared to Its Components and Vehicle in Patients With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: CsA high dose|DRUG: CsA low dose|DRUG: PA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Carcinoma|Peritoneal Carcinoma
Interventions: DRUG: Interferon gamma-1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Purse String Suture Device vs. Endoclip for Immediate Endoscopic Procedure Associated Gastrointestinal Perforation
Status: UNKNOWN
Conditions: Intervention|Gastrointestinal Perforation
Interventions: DEVICE: Purse string suture device|DEVICE: Endoclips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hedgehog Inhibition for Pancreatic Ductal Adenocarcinoma (PDAC) in the Preoperative Setting (HIPPoS)
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: GDC-0449
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Creatine and Glucoseamine/ Chondritin Sulfate Co-Supplementation in Addition to Exercise and Physical Therapy in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Lower Extremity Resistance Exercise Training|OTHER: Home Exercise Plan|DEVICE: Electrotherapy + Heating|PROCEDURE: Joint Mobilization|DIETARY_SUPPLEMENT: Creatine Supplementation|DIETARY_SUPPLEMENT: Glucoseamine/ Chondritin Sulfate Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Impact of School Based Intervention on Motivation Towards Physical Activity and Psychosocial Outcomes Among Adolescents
Status: UNKNOWN
Conditions: School Based Intervention
Interventions: BEHAVIORAL: Active physical education lessons and physical education plan|BEHAVIORAL: Recess or lunch time activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Entecavir Treatment on Regression and Disease Outcome in HBV-induced Liver Fibrosis and Cirrhosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis B|Liver Cirrhosis
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Technology-Based SSIP in Prostate Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Psychosocial Stressor
Interventions: OTHER: WINGS-IP1 Smartphone Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multi-parameters'Change Process During Dehydration Therapy on Brain Edema Patients.
Status: UNKNOWN
Conditions: Hemodynamic Instability|Water on the Brain|Intracranial Pressure Increase
Interventions: PROCEDURE: Mannitol injection|PROCEDURE: Hypertonic saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cancer Associated Thrombosis and Isoquercetin (CATIQ)
Status: COMPLETED
Conditions: Thromboembolism of Vein VTE in Colorectal Cancer|Thromboembolism of Vein in Pancreatic Cancer|Thromboembolism of Vein in Non-small Cell Lung Cancer
Interventions: DRUG: Isoquercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer|ctDNA Genotype|MSS|Failed From Standard Treatment
Interventions: DRUG: HAIC+targeted therapy+PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implitapide in Patients With Hypertriglyceridemia (HTG) on Maximal, Concurrent Triglyceride-Lowering Therapy
Status: TERMINATED
Conditions: Hypertriglyceridemia
Interventions: DRUG: implitapide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiomics and Radiogenomics Models to Predict Molecular Integrated Risk Classes and Prognostic Factors in Endometrial Cancer.
Status: RECRUITING
Conditions: Endometrial Cancer
Interventions: OTHER: trascriptomic profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose-finding Study of L19TNFα Plus Melphalan Using Isolated Inferior Limb Perfusion (ILP) in Subjects With Intransit Stage III/IV Melanoma
Status: COMPLETED
Conditions: Patients With Intransit Stage III/IV Melanoma
Interventions: OTHER: Isolated inferior limb perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Etrasimod (APD334) in Inflammatory Bowel Disease Patients With Active Skin Extra-intestinal Manifestations
Status: TERMINATED
Conditions: Inflammatory Bowel Diseases|Skin Extra-intestinal Manifestations
Interventions: DRUG: APD334
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of the Safety of Escalating Doses of PRO131921 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: PRO131921
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT