pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Preoperative vs. Postoperative Misoprostol in Elective Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Misoprostol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Post-operative Complications of Bone Augmentation at Anterior of Maxilla After Periosteal Releasing Incision With Two Techniques Diode Laser and Scalpel
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: PROCEDURE: Laser-assisted surgery.|PROCEDURE: conventional surgery by blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coadministration of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) With Ribavirin (RBV) in Adults With Genotype 4 (GT4) Hepatitis C Virus (HCV) in Egypt
Status: COMPLETED
Conditions: HCV|Hepatitis C Infection|Genotype 4
Interventions: DRUG: 2 DAA|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Galantamine for the Treatment of Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Placebo|DRUG: Galantamine 16 mg/day|DRUG: Galantamine 24 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sapanisertib in Treating Patients With Stage IV or Recurrent Lung Cancer
Status: COMPLETED
Conditions: Recurrent Lung Squamous Cell Carcinoma|Stage IV Lung Squamous Cell Carcinoma AJCC v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Gallstones in Post-bariatric Surgery Patients：A Prospective Randomized Trial
Status: UNKNOWN
Conditions: Clostridium Butyricum Miyairi|Gallstones|Gastrointestinal Quality of Life Index
Interventions: DRUG: Miyarisan-BM (Clostridium Butyricum Miyairi)|DRUG: Urso group|DRUG: Biotase group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oxulumis®, Suprachoroidal Drug Administration of Triesence® in Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Oxulumis® suprachoroidal microcatheterization administration of Triesence®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas.
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Glioma
Interventions: DRUG: Hydrogen|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Treatment Strategies in Relation to Adherence, Resistance and Virological Treatment Failure
Status: UNKNOWN
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: BEHAVIORAL: Enhanced Treatment Support (ETS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Study to Evaluate Bioavailability of Naproxen as PN400 Compared to Naproxen as Proxen S and Naprosyn E
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PN400|DRUG: Naproxen (Proxen S)|DRUG: Naproxen (Naprosyn E)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: uTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM
Status: ACTIVE_NOT_RECRUITING
Conditions: Sexually Transmitted Diseases|HIV Infections|Implementation Science|Substance Use|MSM
Interventions: BEHAVIORAL: uTECH + YMHP|BEHAVIORAL: YMHP|BEHAVIORAL: uTECH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thromboprophylaxis of Venous Thromboembolism in Acutely-ill Medical Inpatients With Thrombocytopenia
Status: TERMINATED
Conditions: Medical Patient|Thrombocytopenia
Interventions: DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos Patients
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: SIMVASTATIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma
Status: SUSPENDED
Conditions: Endometrial Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Dedifferentiated Carcinoma|Endometrial Endometrioid Adenocarcinoma|Endometrial Mixed Cell Adenocarcinoma|Endometrial Mucinous Adenocarcinoma|Endometrial Undifferentiated Carcinoma|Endometrioid Adenocarcinoma|Recurrent Endometrial Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Aromatherapy to Alleviate Peri Operative Anxiety in Ambulatory Elective Upper Limb Surgery Under Loco-regional Anesthesia
Status: RECRUITING
Conditions: Anxiety
Interventions: OTHER: Olfactory aromatherapy|OTHER: without aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Activation With Protein-rich Formula Diet
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: stringent diet regimen|DIETARY_SUPPLEMENT: moderate diet regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Study Comparing Contour SE™ Microspheres to Embosphere® Microspheres for Treating Symptomatic Uterine Fibroids With Uterine Fibroid Embolization (UFE)
Status: COMPLETED
Conditions: Leiomyoma|Uterine Fibroids|Uterine Neoplasms|Menorrhagia|Leiomyomatosis
Interventions: PROCEDURE: Uterine Fibroid Embolization (UFE)|DEVICE: Contour SE™ Microspheres|DEVICE: Embosphere® Microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liraglutide to Improve corONary Haemodynamics During Exercise streSS
Status: COMPLETED
Conditions: Ischaemic Heart Disease|Coronary Heart Disease|Chronic Stable Angina
Interventions: DRUG: Liraglutide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: STUDY OF THE EFFECT OF RHYTHMIC AND NON-RHYTHMIC MUSICAL PRIMING ON THE SYNTAX CAPACITY OF PRESBYACOUSTIC OLDER ADULTS
Status: NOT_YET_RECRUITING
Conditions: Presbyacousie
Interventions: OTHER: Audiogram|OTHER: Musical priming for the syntax test|OTHER: Test MMSE|OTHER: Barcelona Music Reward Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Choral Singing Help imprOve Stress in Patients With Ischemic HeaRt Disease?
Status: COMPLETED
Conditions: Ischemic Heart Disease|Coronary Heart Disease|Myocardial Infarction
Interventions: BEHAVIORAL: Choral Singing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: MERREM I.V. 2g as a 3 hour infusion every 8 hours|DRUG: vancomycin I.V. 1 g every 12 hours|DRUG: tobramycin I.V. 5 mg/kg every 24 hours|DRUG: MERREM I.V. 1g as a 30 minute infusion every 8 hours|DRUG: MERREM I.V. 500 mg as a 3 hour infusion every 8 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2a and Ribavirin for Genotype 2 Chronic Hepatitis C: Duration and Ribavirin Dose Stratified by RVR
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peg-IFN + WB RBV for 16 weeks|DRUG: Peg-IFN + LD RBV for 16 weeks|DRUG: Peg-IFN + WB RBV for 24 weeks|DRUG: Peg-IFN + WB RBV for 48 weeks|DRUG: Peg-IFN + LD RBV for 24 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Dementia|Late Onset Alzheimer Disease|Neurodegenerative Diseases
Interventions: DRUG: Allopregnanolone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.
Status: RECRUITING
Conditions: Pelvic Cancer|Ovarian Cancer|Cervical Cancer|Uterus Cancer|Endometrial Cancer|Ovarian Neoplasms|Ovarian Carcinoma|Sarcoma Uterus|Metastatic Cancer
Interventions: PROCEDURE: Ultrasound guided tru-cut biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery
Status: TERMINATED
Conditions: Bleeding|Cardiac Defect|Surgery--Complications|Fibrinogenopenia; Acquired|Transfusion-Related Acute Lung Injury|Transfusion-Associated Circulatory Overload|Congenital Heart Disease
Interventions: DRUG: Fibrinogen Concentrate Human|DRUG: Prothrombin Complex Concentrate|BIOLOGICAL: Fresh Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Of Zy-19489 Administered Via Oral Route To Investigate The Safety, Tolerability And Pharmacokinetics In Healthy Adult Human Subjects
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: ZY19489 Capsule|DRUG: Placebo Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Drug Availability Of Methylprednisolone In Liquid Form Versus Methylprednisolone In Tablet Form
Status: COMPLETED
Conditions: Biological Availability
Interventions: DRUG: methylprednisolone|DRUG: methylprednisolone|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Indomethacin in Difficult Embryo Transfer.
Status: UNKNOWN
Conditions: Difficult Embryo Transfer
Interventions: DRUG: Indomethacin(KAHIRA PHARMA&CHEM,IND,CO.CAIRO-EGYPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of Hemp Phenolics
Status: ACTIVE_NOT_RECRUITING
Conditions: Bioavailability|Metabolites|Excretion
Interventions: DIETARY_SUPPLEMENT: Low dose dietary fiber|DIETARY_SUPPLEMENT: High dose dietary fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study
Status: COMPLETED
Conditions: Colonic Neoplasms|Rectal Neoplasms
Interventions: RADIATION: First-Line Bevacizumab and Chemotherapy|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Stepped Approach to Improving Sexual Function aFteR Treatment fOr gyNaecological Cancer
Status: UNKNOWN
Conditions: Cervical Cancer|Ovarian Cancer|Uterine Cancer|Vaginal Cancer|Vulval Cancer|Psychosexual Dysfunctions
Interventions: BEHAVIORAL: SAFFRON stepped care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decolonization of Carbapenem-resistant Enterobacterales (CRE) in Patients With Faecal Carriage of CRE With Neomycin
Status: RECRUITING
Conditions: Colonization, Asymptomatic
Interventions: DRUG: Neomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 13-Week, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study Of Pregabalin For Postherpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: Placebo|DRUG: Pregabalin|DRUG: Pregabalin|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Botox and rehab|DRUG: Placebo and rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Doses of Formoterol Fumarate MDI (PT005) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), Compared to Foradil® Aerolizer® as an Active Control
Status: WITHDRAWN
Conditions: COPD
Interventions: DRUG: Inhaled PT005|DRUG: Inhaled Placebo|DRUG: Formoterol Fumarate 12 µg (Foradil Aerolizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Evaluation of the Lip Support in a Full-arch Implant-supported Rehabilitations
Status: RECRUITING
Conditions: Digital Technology|Prosthesis User|Lip|Oral Soft Tissue Conditions|Occlusion
Interventions: PROCEDURE: Removable of the full arch implant-supported prostheses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Double-Blind, Dose-Escalation Study of IDX184 in Chronic Hepatitis C Treatment-Naïve Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C (HCV)
Interventions: DRUG: IDX184
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: TRx0237 16 mg/day|DRUG: Placebo|DRUG: TRx0237 8 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Clinical Pharmacist on the Quality and Cost of the Therapeutic Management of Patients in Two Medical Services of a Teaching Hospital
Status: COMPLETED
Conditions: Admitted to Infectiology or Internal Medicine Wards
Interventions: OTHER: Pharmacist consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Mobile-delivered Sleep Restriction Therapy for Treatment of Insomnia Disorder: Randomised Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Insomnia
Interventions: OTHER: SleepFix|OTHER: Sleep health Education modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open, Study to Assess the Safety of RGTA® (OTR4132) in Patients With Acute Ischemic Stroke (AIS)
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DEVICE: OTR4132MD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Crizotinib Versus Chemotherapy In Previously Untreated ALK Positive East Asian Non-Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: NSCLC (Non-small Cell Lung Cancer)
Interventions: DRUG: Crizotinib|DRUG: Pemetrexed/Cisplatin|DRUG: Pemetrexed/Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eustachian Tube Dysfunction Assessment
Status: COMPLETED
Conditions: Eustachian Tube Dysfunction
Interventions: DEVICE: EMG recording|DEVICE: Tympanic Cavity Air Exchange Test|DEVICE: Tympanometer test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Machine Learning-based Classification of Symptom Clusters and Online CBT
Status: NOT_YET_RECRUITING
Conditions: Depression and Anxiety Symptom
Interventions: BEHAVIORAL: cognitive behavior therapy|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuation Trial Evaluating the Tolerability and Activity of FK228 in Patients That Completed Prior Study With FK228
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Prostatic Neoplasms
Interventions: DRUG: FK228 (romidepsin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA)
Status: RECRUITING
Conditions: Clopidogrel, Poor Metabolism of|Carotid Stenosis
Interventions: DRUG: Clopidogrel|DRUG: Ticagrelor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®
Status: COMPLETED
Conditions: Heart Transplantation|Lung Transplantation|Pancreas (Including SPK) Transplantation
Interventions: DRUG: Advagraf|DRUG: Prograf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Consolidative Radiotherapy Combined With Camrelizumab and Chemotherapy for Oligometastatic Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Oligometastatic Disease
Interventions: RADIATION: consolidative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Effects of Freeze-Dried Strawberry Beverage on Cardiovascular Risk Factors
Status: COMPLETED
Conditions: Dyslipidemia|Obesity
Interventions: DIETARY_SUPPLEMENT: Freeze-dried strawberries|DIETARY_SUPPLEMENT: Dietary fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety of agenT-797 in Participants With Moderate to Severe Difficulty Breathing Secondary to SARS-CoV-2
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult
Interventions: DRUG: agenT-797
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure Serum Periostin, Asthma-Related Biomarkers and Response to Prednisolone in Adult and Adolescent Patients With Severe Oral Corticosteroid-Dependent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: LABA|DRUG: corticosteroids|DRUG: prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: MLN9708
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARVAC-A New Recombinant Coronavirus Disease 2019 (COVID-19) Vaccine
Status: COMPLETED
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: Gamma Variant RBD-based ARVAC-CG vaccine|BIOLOGICAL: Omicron Variant RBD-based ARVAC-CG vaccine|BIOLOGICAL: Bivalent RBD-based ARVAC-CG vaccine|OTHER: Placebo (Alum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study
Status: RECRUITING
Conditions: Wheezing|Asthma in Children
Interventions: DRUG: Soy isoflavone|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multicenter,2-Arm,Randomized,Controlled Study Evaluate the Effectiveness of the UltraShape® Contour I VER 3.1 System for Non-Invasive Reduction in Abdominal Circumference
Status: COMPLETED
Conditions: Body Sculpting
Interventions: DEVICE: Non Invasive Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study of the Safety, Blood Levels and Biological Effects of Aes-103 Compared to Placebo in Subjects With Stable Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Aes-103|DRUG: Aes-103|DRUG: Aes-103|DRUG: Aes-103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of N9 Chemotherapy in Children With Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma|Pediatric Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Topotecan|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Carboplatin|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: DRUG: Donepezil Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vagus Nerve Stimulator for Autism and Other Developmental Disorders
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Intellectual Disability|Autonomic Nervous System|Developmental Disability
Interventions: DEVICE: Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetic and Pharmacodynamic Parameters of Filgrastim (G-CSF)Produced by Blausiegel Indústria e Comércio Ltda. Compared to Granulokine Produced by Produtos Roche Químicos e Farmacêuticos S/A.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Filgrastim|DRUG: Filgrastim|DRUG: Filgrastim|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium Electroporation for Treatment of Cutaneous Metastases
Status: COMPLETED
Conditions: Cutaneous Metastases
Interventions: DRUG: Calcium electroporation|DRUG: Electrochemotherapy with bleomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Radiotherapy in Rectal Cancer Using Oxaliplatin, Capecitabine With or Without Cetuximab
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: DRUG: Capecitabine, Cetuximab, Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation by Colonoscopy for Recurrent C. Difficile Infection
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: OTHER: Fecal Microbiota Transplantation|DRUG: Standard Antibiotic Therapy|DRUG: Vancomycin (before randomization)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Treatment of Anemia in Rehabilitation Patients
Status: TERMINATED
Conditions: Anemia
Interventions: DRUG: placebo|DRUG: epoetin alpha|DRUG: Niferex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Sacropexy and Vaginal Natural Orifice Transluminal Endoscopic Surgery Shull Suspension Comparison Trial
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Laparoscopic cervicosacropexy|PROCEDURE: Shull technique via V-NOTES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wound Infiltration With Ketorolac Versus Lidocaine for Postoperative Analgesia After Total Abdominal Hysterectomy
Status: UNKNOWN
Conditions: Anesthesia
Interventions: PROCEDURE: Wound infiltration|DRUG: Lidocaine Hydrochloride|DRUG: Ketorolac tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Modified Release (MR) Tacrolimus/Mycophenolate Mofetil (MMF) in de Novo Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus Modified Release (MR)|DRUG: Tacrolimus|DRUG: cyclosporine microemulsion|DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Complementary Therapies for the Reduction of Side Effects During Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: two complex naturopathic add-on therapies, leaflet 5-a-day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of FLU-v in an H1N1 Influenza Human Challenge Model
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: adjuvanted FLU-v|BIOLOGICAL: adjuvanted placebo|OTHER: Influenza challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Abciximab i.v. Versus i.c. in ST-elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST-elevation Myocardial Infarction
Interventions: DRUG: abciximab intracoronary|DRUG: abciximab intravenously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: OTHER: Cognitive Bias Modification for Interpretations (CBM-I)|OTHER: Interpretation Control Condition (ICC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Septal Pacing in Patients With Right Bundle Branch Block and Heart Failure (The SPARK Trial)
Status: TERMINATED
Conditions: Right Bundle-Branch Block|Heart Failure
Interventions: DEVICE: RV DDD(R)-60 with AV optimization|DEVICE: RV DDD(R)-60
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exercise-Induced Hypoglycemia Prevention in Adults With Type 1 Diabetes Using an Artificial Pancreas
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia
Interventions: DEVICE: EnMPC (Ensemble Model Predictive Control) AP Controller|DEVICE: rMPC (Naïve Model Predictive Control) AP Controller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Cancer|Carcinoma|Castrate-Resistant Prostate Cancer|Prostate Cancer|Tumors
Interventions: DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults
Status: COMPLETED
Conditions: Genital Herpes Simplex Type 2
Interventions: BIOLOGICAL: VCL-HB01|BIOLOGICAL: VCL-HM01|BIOLOGICAL: PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Dexamethasone|BIOLOGICAL: Autologous Tumor Cell-Based Vaccine|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD of LGT209 in Healthy Volunteers and Patients With Hypercholesterolemia
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: LGT209|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitative Effect of the Use of a Gait Exoskeleton in Patients With Neuromuscular Disease or Cerebral Palsy
Status: COMPLETED
Conditions: Neuromuscular Diseases|Cerebral Palsy|SMA II
Interventions: DEVICE: ATLAS 2030
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIETARY_SUPPLEMENT: LC-1000|DIETARY_SUPPLEMENT: LC-2000|DIETARY_SUPPLEMENT: Q10-150|DIETARY_SUPPLEMENT: Q10-300|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Long Acting Anticholinergic on Nocturnal Incontinence After Radical Cystectomy and Orthotopic Neobladder
Status: COMPLETED
Conditions: Nocturnal Incontinence
Interventions: DRUG: long acting tolterodine 4 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Mechanical Load on Metabolic Exercise Adaptations in Response to Weight Loss in Obese Adolescents: The POWELL Study
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: Multidisciplinary weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalizing Interventions Using Real-World Interactions
Status: COMPLETED
Conditions: Social Interaction|Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: BEHAVIORAL: Tailored MERIT|BEHAVIORAL: Standard MERIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automated Hovering to Improve Medication Adherence Among Myocardial Infarction Patients (Heartstrong)
Status: COMPLETED
Conditions: Patients With Principal or Secondary Diagnosis Code of Intrntl Classification of Diseases, 9th Revision, (ICD-9-CM) 410 (Except When 5th Digit Was 2)
Interventions: BEHAVIORAL: Electronic Pill Bottle, Incentives, Social Influence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Injection of Ranibizumab Versus Combination of Ranibizumab and Triamcinolone Acetate for (CRVO)
Status: UNKNOWN
Conditions: Ophthalmopathy
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab|DRUG: triamcinolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of SM-13496 in Patients With Bipolar I Depression.
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Placebo|DRUG: SM-13496|DRUG: SM-13496
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Indicators and Patient Experience in 7G and 10G Vacuum-assisted Excision of Probably Benign Breast Lesions
Status: RECRUITING
Conditions: Breast Diseases
Interventions: DEVICE: Excision with 7G needle|DEVICE: Excision with 10G needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Safety of Emicizumab SC Injection in Korean Hemophilia A Patients With/Without FVIII Inhibitors
Status: RECRUITING
Conditions: Hemophilia A With Inhibitor|Hemophilia A Without Inhibitor
Interventions: DRUG: Emicizumab subcutaneous injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Massage and Cold Water Immersion on Movement Variability an Muscle Tone of Swimmers
Status: NOT_YET_RECRUITING
Conditions: Movement Disorders|Muscle Tone
Interventions: OTHER: Massage|OTHER: Cold water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Dose Response Study in Japan in Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits
Status: COMPLETED
Conditions: Pneumonia|Acute Respiratory Disease
Interventions: BIOLOGICAL: 23-valent pneumococcal vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dichoptic Treatment vs. Patching for Moderate Anisometropic Amblyopia
Status: UNKNOWN
Conditions: Amblyopia|Anisometropia
Interventions: OTHER: Dichoptic treatment using virtual reality|OTHER: Patching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of SGI-1776, A PIM Kinase Inhibitor in Refractory Prostate Cancer and Relapsed/Refractory Non Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Prostate Cancer|Non-Hodgkins Lymphoma
Interventions: DRUG: SGI-1776
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spondylolisthesis|Grade 1 Spondylolisthesis|Lumbar Spinal Stenosis|Degenerative Spondylolisthesis
Interventions: OTHER: Expert Panel Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of the Vibrant Capsule Administered 5 Times Per Week
Status: COMPLETED
Conditions: Constipation
Interventions: DEVICE: Vibrant capsule|DEVICE: Sham capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vitamin A and Zinc Supplementation on Malarial Morbidity
Status: COMPLETED
Conditions: Malaria|Malnutrition
Interventions: DIETARY_SUPPLEMENT: vitamin A|DIETARY_SUPPLEMENT: vitamin A and zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Microbial Associations in Periodontal Health and Disease
Status: COMPLETED
Conditions: Periodontitis|Periodontal Diseases
Interventions: DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Applying a Bandage Skin Hydrogel on the Pains of the Head and Neck in Patients With Cancer of Head and Neck Treated With Radiotherapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DEVICE: bandage skin Hydrotac®|DRUG: Ialuset®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pretreatment With HCQ Before Radiotherapy and Chemotherapy in Advanced NPC Patients
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: HCQ|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Child Health Improvement Through Computer Automation (CHICA) Highlighting Study
Status: COMPLETED
Conditions: Physician Behavior
Interventions: OTHER: Receiving Highlighted Prompts|OTHER: Receiving Non-highlighted Prompts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Budesonide Multimatrix(MMX) Versus Prednisolone in Management of Mild to Moderate Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis Chronic
Interventions: DRUG: Budesonide MMX|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RCT Deep vs Moderat NMB on Surgical Conditions During THP
Status: UNKNOWN
Conditions: Muscle Injury
Interventions: PROCEDURE: deep NMB|PROCEDURE: moderate NMB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter Study for Evaluating a Digital Support System in Childhood Obesity Treatment
Status: RECRUITING
Conditions: Childhood Obesity|Adolescent Obesity|mHealth|Personalized Medicine
Interventions: BEHAVIORAL: Evira Care treatment|BEHAVIORAL: Standard Lifestyle Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors|Breast Cancer|Cognitive/Functional Effects|Drug/Agent Toxicity by Tissue/Organ|Psychosocial Effects of Cancer and Its Treatment
Interventions: BIOLOGICAL: trastuzumab|DRUG: carboplatin|DRUG: methotrexate|DRUG: sodium thiosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of CD19 Chimeric Antigen Receptor T Cells for Pediatric Patients With CD19-positive B-cell Acute Lymphoblastic Leukemia Who Are Indicated for Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Very High Risk Acute Lymphoblastic Leukemia|CD19 CAR-T Therapy
Interventions: GENETIC: SNUH-CD19-CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperpolarized 13C-pyruvate Metabolic MRI With Traumatic Brain Injury
Status: RECRUITING
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage
Interventions: DRUG: Hyperpolarized 13C-Pyruvate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Omega-3 LipoMicel® soft gels|DIETARY_SUPPLEMENT: RxOmega-3 soft gels (Enteric)|DIETARY_SUPPLEMENT: Omega-3 Complete soft gels (Non-Enteric)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars
Status: TERMINATED
Conditions: Fibrosis
Interventions: DRUG: Triamcinolone acetonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of Relatlimab Plus Nivolumab in Pediatric and Young Adults With Hodgkin and Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: DRUG: Relatlimab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Plus Tobramycin/Dexamethasone Versus Tobramycin/Dexamethasone After Uneventful Phacoemulsification Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Drug: Tobramycin 0.3% - Dexamethasone 0.1%|DRUG: Drug: Tobramycin-Dexamethasone plus Ketorolac tromethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: COLD-fX|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of P-3058 10% Nail Solution in the Treatment of Toenail Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: P-3058 10%|DRUG: vehicle of P-3058 10%|DRUG: amorolfine 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: paclitaxel albumin-stabilized nanoparticle formulation|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1|Plexiform Neurofibroma|NF1
Interventions: DRUG: FCN-159
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents.
Status: TERMINATED
Conditions: Prostate Cancer Metastatic|Prostate Cancer
Interventions: DRUG: ODM-201|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT