pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: BEAM vs. 90-Yttrium Ibritumomab Tiuxetan (Zevalin®)/BEAM With ASCT for Relapsed DLBCL
Status: TERMINATED
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: RADIATION: 90-Yttrium Ibritumomab tiuxetan|DRUG: Carmustine|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Melphalan|PROCEDURE: Autologous Hematopoietic Stem Cell Transplant|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Tumor Necrosis Factor Therapy In Patients With Ankylosing Spondylitis
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: TNF alpha|DRUG: NSAIDs and sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Severe Obesity
Interventions: DRUG: Chenodeoxycholic Acid|DRUG: Colesevelam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic Study Between Two Extended-Release Cilostazol Formulations in Korea
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DRUG: Cilostan CR Tab.|DRUG: Pletaal SR Cap.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacterial Intestinal Gut Modification Around Cancer Surgery (BIG MACS) Diet
Status: ACTIVE_NOT_RECRUITING
Conditions: Dysbiosis|Sarcopenia|Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Standard Diet|DIETARY_SUPPLEMENT: BIG MACS Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EF-41/KEYNOTE D58: Phase 3 Study of Optune Concomitant With Temozolomide Plus Pembrolizumab in Newly Diagnosed Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: DEVICE: Optune® device|DRUG: Temozolomide|DRUG: Pembrolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analyzing IBS to Identify Biomarkers and Microbiome Signatures
Status: COMPLETED
Conditions: Diarrhoea Predominant Irritable Bowel Syndrome|IBS
Interventions: PROCEDURE: endoscopy for tissue biopsy|OTHER: Blood Sample|OTHER: Stool Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ACT With Feedback for Post Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: BEHAVIORAL: Attention Control Training (ACT) with ABV feedback|BEHAVIORAL: Attention Control Training (ACT) with yoked sham feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Amiodarone|DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Tolerability Study of AVT04 to EU Approved and US Licensed Stelara (Ustekinumab)
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Stelara PFS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema
Status: COMPLETED
Conditions: Eczema
Interventions: DRUG: alitretinoin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors
Status: RECRUITING
Conditions: Recurrent Cutaneous Melanoma|Recurrent Lip and Oral Cavity Carcinoma|Recurrent Malignant Endocrine Neoplasm|Recurrent Malignant Female Reproductive System Neoplasm|Recurrent Malignant Male Reproductive System Neoplasm|Recurrent Malignant Mesothelioma|Recurrent Malignant Neoplasm of Multiple Primary Sites|Recurrent Malignant Oral Neoplasm|Recurrent Malignant Pharyngeal Neoplasm|Recurrent Malignant Skin Neoplasm|Recurrent Malignant Soft Tissue Neoplasm|Recurrent Malignant Solid Neoplasm|Recurrent Malignant Thyroid Gland Neoplasm|Recurrent Malignant Urinary System Neoplasm|Refractory Cutaneous Melanoma|Refractory Malignant Bone Neoplasm|Refractory Malignant Endocrine Neoplasm|Refractory Malignant Female Reproductive System Neoplasm|Refractory Malignant Male Reproductive System Neoplasm|Refractory Malignant Mesothelioma|Refractory Malignant Neoplasm of Multiple Primary Sites|Refractory Malignant Oral Neoplasm|Refractory Malignant Pharyngeal Neoplasm|Refractory Malignant Skin Neoplasm|Refractory Malignant Soft Tissue Neoplasm|Refractory Malignant Solid Neoplasm|Refractory Malignant Thyroid Gland Neoplasm|Refractory Malignant Urinary System Neoplasm
Interventions: BIOLOGICAL: Cord Blood-derived Expanded Allogeneic Natural Killer Cells|DRUG: Cyclophosphamide|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Monthly Subcutaneous or Intravenous Mircera in Dialysis Patients With Chronic Renal Anaemia
Status: COMPLETED
Conditions: Anemia
Interventions: PROCEDURE: Dialysis|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Ondansetron Orally Disintegrating Tablets 8 mg to Zofran ODT® Tablets 8 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ondansetron Orally Disintegrating Tablets 8 mg|DRUG: Zofran ODT® Tablets 8 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Predictors of Response to Neoadjuvant Docetaxel-Carboplatin Chemotherapy for Patients With Stage II and III Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Cancer Stage II-III
Interventions: DRUG: Docetaxel- Carboplatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Osteopathic Techniques on Residual Volume in Severe Chronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: COPD
Interventions: OTHER: osteopathic manual therapy|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Dermal Fillers
Interventions: DEVICE: LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Patients With Richter's Syndrome;
Status: RECRUITING
Conditions: Richter's Syndrome
Interventions: COMBINATION_PRODUCT: Obinutuzumab with Ibrutinib and Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Changes During Moderate Intensity Strength Training in Aortic Stent-graft Patients
Status: COMPLETED
Conditions: Aortic Stent Graft
Interventions: OTHER: Moderate Intensity Muscle Strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of a Functional Re-education and Environmental Adaptation Programme in Cancer Patients With Associated Respiratory Pathology
Status: NOT_YET_RECRUITING
Conditions: Cancer|Dyspnea|Functionality|Quality of Life|Functional Capacity
Interventions: OTHER: FUNCTIONAL REEDUCATION AND ENVIRONMENTAL ADAPTATION PROGRAMME|OTHER: Health education programme:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Global Postural Exercises Versus Specific Therapeutic Neck Exercises in Chronic Non-specific Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Global Postural Reeducation|OTHER: Exercise Therapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of IMC-001 in Subjects With Relapsed or Refractory Extranodal NK/T Cell Lymphoma, Nasal Type
Status: ACTIVE_NOT_RECRUITING
Conditions: Extranodal NK/T-cell Lymphoma, Nasal Type|Extranodal NK/T-cell Lymphoma
Interventions: DRUG: IMC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VenusP-Valve Pivotal Study (PROTEUS STUDY)
Status: RECRUITING
Conditions: Pulmonary Regurgitation
Interventions: DEVICE: Transcatheter pulmonary valve implantation (TPVI)|DEVICE: VenusP-ValveTM System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Patients With Recurrent Mature B-Cell Neoplasms
Status: COMPLETED
Conditions: Recurrent Mature B-cell Neoplasms
Interventions: DRUG: PCI-32765
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Status: RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Relapsed Non Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Non Hodgkin Lymphoma|Lymphoma|B Cell Lymphoma|B Cell Non-Hodgkin's Lymphoma
Interventions: GENETIC: CB-010|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Multifamily Groups to Improve Self-Management of Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: BEHAVIORAL: Tomando Control-Nurse|BEHAVIORAL: Tomando Control-Promotora|BEHAVIORAL: Enhanced engagement|BEHAVIORAL: Multifamily Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored COVID-19 Testing Support Plan for Francophone African Born Immigrants
Status: NOT_YET_RECRUITING
Conditions: COVID19 Testing
Interventions: BEHAVIORAL: FABI tailored COVID-19 testing pamphlet|BEHAVIORAL: Standard COVID-19 home-based test kit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: ABSK121-NX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating Nivolumab-containing Treatments in Patients With Advanced Non-small Cell Lung Cancer After Failing Previous PD-1/(L)1 Therapy and Chemotherapy
Status: WITHDRAWN
Conditions: Carcinoma, Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: nivolumab|BIOLOGICAL: ipilimumab|DRUG: cabozantinib|BIOLOGICAL: docetaxel|BIOLOGICAL: ramucirumab|DRUG: lucitanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Sodium Deoxycholate Injections With or Without Triamcinolone for Reduction of Submental Fat
Status: COMPLETED
Conditions: Fat Reduction
Interventions: DRUG: Sodium Deoxycholate|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dopamine on Pulmonary Diffusion and Capillary Blood Volume During Exercise
Status: ACTIVE_NOT_RECRUITING
Conditions: Health
Interventions: DRUG: Dopamine|DRUG: Metoclopramide|DRUG: Placebos|OTHER: Rest|OTHER: Exercise - 60%|OTHER: Exercise - 85%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Safety and Effectiveness Study of SABER®-Bupivacaine for Pain Following Shoulder Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: SABER-Bupivacaine|DRUG: SABER-Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maxigesic IV Phase 3 Bunionectomy Study
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Maxigesic IV|DRUG: IV Acetaminophen|DRUG: IV Ibuprofen|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics Study of Alogliptin in Healthy Korean Participants
Status: COMPLETED
Conditions: Pharmacokinetics and Pharmacodynamics
Interventions: DRUG: Alogliptin|DRUG: Alogliptin|DRUG: Alogliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Combined Alcohol and Cannabis Effects on Skills of Young Drivers
Status: COMPLETED
Conditions: Psychomotor Impairment
Interventions: DRUG: delta 9 tetrahydrocannabinol|DRUG: placebo delta 9 tetrahydrocannabinol|DRUG: Alcohol|DRUG: Placebo alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Benign Prostatic Hyperplasia (BPH) Screening Tool Case Finding Study in Subjects >=50 Years
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: OTHER: Benign prostatic enlargement (BPE)/Benign prostatic obstruction (BPO) screening tool|OTHER: International Prostate Symptom Score (IPSS) screening tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetic Interactions and Safety Study of Telmisartan and Chlorthalidone
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan 80mg|DRUG: Chlorthalidone 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Portable Oxygen Concentrator in Non-hospitalized Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Inogen Rove 6 Portable Oxygen Concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Infiltration Analgesia With Femoral Nerve Block After Hamstrings Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Injury of Anterior Cruciate Ligament
Interventions: PROCEDURE: Femoral nerve block|PROCEDURE: Local infiltration analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Iron Supplements on the Pharmacokinetics of MT-6548
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MT-6548|DRUG: Iron supplement A|DRUG: Iron supplement B|DRUG: Iron supplement C|DRUG: Iron supplement D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tandem Polyurethane Stents Compared to Single Silicone Stent for Malignant Ureteral Obstruction
Status: NOT_YET_RECRUITING
Conditions: Hydronephrosis; Obstruction, Ureter|Renal Failure|Malignancy|Ureter Obstruction|Ureter Stricture
Interventions: DEVICE: ureteral stent\s insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emails Promoting Mail-order Pharmacy
Status: COMPLETED
Conditions: Health Care Utilization
Interventions: BEHAVIORAL: Fear Appeals|BEHAVIORAL: Message about Future Healthcare Costs|BEHAVIORAL: Endorsement from a Doctor|BEHAVIORAL: Comparison Table|BEHAVIORAL: Highlighting Cost Savings and Convenience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Atmo SmartPill Comparison in Gastroparetic and Slow Transit Constipation Patients
Status: COMPLETED
Conditions: Gastroparesis|Slow Transit
Interventions: DEVICE: Atmo gas capsule|DEVICE: SmartPill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MOSTEGRA TRIAL:MO-(Dified) STE-(nt) GRA(-ft): Surgeon-modified Fenestrated-branched Stent-grafts
Status: TERMINATED
Conditions: Complex Aortic Aneurysms
Interventions: DEVICE: surgeon-modified fenestrated-branched stent-grafts (sm-FBSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Maxigesic in Breast Cancer Surgery
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Maxigesic|DRUG: 0.9% saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Perioperative Treatment of Resectable Intrahepatic Cholangiocarcinoma With the Combination of Adebrelimab and Apatinib and HAIC
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: HAIC|DRUG: Adebrelimab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial Comparing Imipenem and Tigecycline Versus Imipenem and Tigecycline With GM-CSF for the Management of Spontaneous Bacterial Peritonitis Presenting With Septic Shock.
Status: UNKNOWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Imipenem|DRUG: Tigecycline|DRUG: GMCSF|DRUG: Colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vibration and Cold Application on Chest Tube Removal Pain After CABG
Status: NOT_YET_RECRUITING
Conditions: Pain, Procedural|Pain, Postoperative|Coronary Artery Bypass Surgery|Chest Tubes
Interventions: DEVICE: Vibration device|OTHER: Vibration device&Cold application pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemithyroidectomy or Total-Thyroidectomy in 'Low-risk' Thyroid Cancers
Status: RECRUITING
Conditions: Differentiated Thyroid Cancer
Interventions: PROCEDURE: Total Thyroidectomy|PROCEDURE: Hemithyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Versus Differed Arterial Catheterization in Critically Ill Patients With Acute Circulatory Failure:
Status: COMPLETED
Conditions: Acute Circulatory Failure
Interventions: PROCEDURE: Non-invasive strategy|PROCEDURE: Control strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison Between Robotic (RM) and Laparoscopic Myomectomy (LM)
Status: UNKNOWN
Conditions: Uterine Leiomyoma|Surgical Procedure, Unspecified
Interventions: PROCEDURE: RM|PROCEDURE: LM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Walking Exercise on Memory, Subjective Cognitive Complaint, and Brain-derived Neurotrophic Factor for Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pulsed Radiofrequency Therapy vs Canal Adductor Blockade in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Canal adductor blockade|PROCEDURE: Canal adductor pulsed radio-frequency therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aminolaevulinic Acid Photodynamic Therapy for HPV+ Low Grade Cervical Intraepithelial Neoplasia (LSIL;CIN1)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Low-Grade Squamous Intraepithelial Lesions|Papillomavirus Infections
Interventions: DRUG: Aminolaevulinic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Gebasaxturev (V937) Administered Intravenously or Intratumorally With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants With Advanced/Metastatic Melanoma (V937-011)
Status: TERMINATED
Conditions: Advanced/Metastatic Melanoma
Interventions: BIOLOGICAL: Gebasaxturev IV|BIOLOGICAL: Gebasaxturev ITu|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Tracheal Balloon Occlusion in Unborns With Severe Congenital Diaphragmatic Hernia - EUROTRIAL I
Status: WITHDRAWN
Conditions: Diaphragmatic Hernia
Interventions: PROCEDURE: Fetoscopic tracheal balloon occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Sociolinguistic-enabled Web Application to Develop Precision Health Intervention for African Americans
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Dialectal Features Varied|BEHAVIORAL: Video Intervention|BEHAVIORAL: VHA with no voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Development and Evaluation of a CBT-based Transdiagnostic Transcultural Web App for Mental Health Problems
Status: RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Web-based CBT guided self-help Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Pumpkin Seeds Phonophoresis on Chronic Non-bacterial Prostatitis
Status: COMPLETED
Conditions: Chronic Non-bacterial Prostatitis
Interventions: OTHER: phonophoresis treatment using pumpkin seeds oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ELA026 in Single and Multiple Doses in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ELA026|DRUG: ELA026
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Transcranial Alternating Current Stimulation on Patients With Delirium and Critical Illness (DeliTACS)
Status: NOT_YET_RECRUITING
Conditions: Delirium
Interventions: DEVICE: Transcranial alternating current stimulation (TACS)|DEVICE: Sham TACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Intravenous IntralipidTherapyon Pregnancy Outcome in Women With History of Recurrent Implantation Failure Undergoing Intracytoplasmic Sperm Injection-Embryo Transfer Cycle: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Infertility Due to Nonimplantation
Interventions: DRUG: intralipid 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Intrahepatic Cholangiocarcinoma|Oligometastatic Intrahepatic Cholangiocarcinoma|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Unresectable Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: Angiography|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|BIOLOGICAL: Durvalumab|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Tremelimumab|PROCEDURE: Yttrium-90 Microsphere Radioembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study That Tests BI 1467335 in Patients With Diabetic Eye Disease (Diabetic Retinopathy). It Looks at the Way BI 1467335 is Taken up, the Effects it Has, and How Well it is Tolerated.
Status: COMPLETED
Conditions: Diabetic Retinopathy
Interventions: DRUG: BI 1467335|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients.
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: CAD106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Interval Between Cycles of PRRT With 177lu-dotatate in sstr2 Positive Tumors
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DRUG: PRRT every 5 weeks|DRUG: PRRT every 8-10 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline for Postsurgical Symptom Reduction in Head and Neck Cancer
Status: TERMINATED
Conditions: Head And Neck Cancer
Interventions: DRUG: Minocycline|DRUG: Placebo|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesia for Insertion of Intrauterine Contraception
Status: COMPLETED
Conditions: Insertion of Intrauterine Contraception
Interventions: DRUG: Mepivacaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SSP-004184 (SPD602) in Healthy Adults and Subjects With Impaired Liver Function
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: SSP-004184
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Elastic Restraint to LESSen the Effects of Heart Failure (PEERLESS-HF) Trial
Status: TERMINATED
Conditions: Heart Failure
Interventions: DEVICE: HeartNet Ventricular Support System|DRUG: Optimal Medical/Device Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical Electrical Stimulation for ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: CES at rest|DEVICE: CES plus active hand or wrist movements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobile Phone Intervention to Reduce Youth Suicide in Rural Communities
Status: COMPLETED
Conditions: Help-Seeking Behavior|Emotions|Trusted Adults|Suicide|Positive Affect
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Anonymous Testing of Pathology Specimens for BRCA Mutations in Ashkenazi Jewish Individuals Who Have Cancer
Status: WITHDRAWN
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Gastric Cancer|Lung Cancer|Melanoma|Non-Hodgkin's Lymphoma|Uterine Cancer|CORPUS UTERI,ENDOMETRIUM|LUNG|OVARY
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Frequency of Performing Umbilical Artery Doppler in the Third Trimester in High Risk Pregnancy
Status: COMPLETED
Conditions: High Risk Pregnancy
Interventions: DIAGNOSTIC_TEST: Umbilical artery Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Spyglass DS Peroral Cholangioscope Guided LL or EHL Versus BML for Endoscopic Removal of Complicated Bile Duct Stones
Status: RECRUITING
Conditions: Biliary Stones
Interventions: DEVICE: Spyglass DS cholangioscope|DEVICE: BML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline for the Treatment of Cannabis and Tobacco Use Disorders in Veterans
Status: WITHDRAWN
Conditions: Tobacco Use Disorder|Cannabis Use Disorder
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Iliac and Renal Artery for Mechanism of Intracranial Aneurysm in ADPKD
Status: UNKNOWN
Conditions: Kidney Transplant; Complications|Polycystic Kidney Diseases|Aneurysm, Brain
Interventions: PROCEDURE: Kidney transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transumbilical Versus Lateral Transabdominal Removal of Benign Adnexal Masses Via Laparoscopy
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: Transumbilical removal of specimen via laparoscopy|PROCEDURE: Lateral transabdominal removal of specimen via laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Esophageal Multisegmented FCSEMS for Malignant Strictures
Status: TERMINATED
Conditions: Oesophageal Cancer|Esophageal Stent Stenosis
Interventions: DEVICE: Multisegmented fully covered self-expandable metal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Statin Medications on Muscle Performance (The STOMP Study)
Status: COMPLETED
Conditions: Hydroxymethylglutaryl-CoA Reductase Inhibitors|Muscular Diseases
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Neuroplasticity on Depressed Patients : Modulation of MEP Induced by Theta Burst Stimulation
Status: COMPLETED
Conditions: Depression
Interventions: DEVICE: Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjects
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide Autogel 120 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multichannel Vestibular Implant Early Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Disorders of Vestibular Function, Bilateral|Bilateral Vestibular Deficiency (BVD)|Gentamicin Ototoxicity|Labyrinth Diseases|Vestibular Diseases|Sensation Disorders
Interventions: DEVICE: Labyrinth Devices MVI™ Multichannel Vestibular Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
Status: COMPLETED
Conditions: Asthma|Wheeze|Obstructive Sleep Apnea|Food Allergy|Virus
Interventions: PROCEDURE: Bronchodilator response|PROCEDURE: Allergy Skin Test|PROCEDURE: Multiple-Breath Washout|PROCEDURE: Forced Oscillation Technique|PROCEDURE: Spirometry|DRUG: salbutamol|PROCEDURE: Nasal Brush|PROCEDURE: Blood sample|PROCEDURE: Basophil activation test|PROCEDURE: Nasal swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-articular Tranexamic Acid in the Reduction of Blood Transfusions in Primary Total Hip and Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Tranexamic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Remote Ischemic Conditioning and Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer|Diabetic Angiopathies
Interventions: DEVICE: Remote Ischemic conditioning (RIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Hodgkin's Lymphoma
Status: RECRUITING
Conditions: Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Auto CAR-T|DRUG: Cyclophosphamide,Fludarabine|PROCEDURE: Leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of a Study Product on Quality of Life and Mood
Status: COMPLETED
Conditions: Quality of Life|Mood
Interventions: DIETARY_SUPPLEMENT: Eurycomalongifoliawater extract (Physta®)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Development of a Bayesian Estimator for Calculating Plasma Iohexol Clearance
Status: NOT_YET_RECRUITING
Conditions: Kidney Function Test
Interventions: DRUG: Iohexol|BIOLOGICAL: pharmacokinetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequential Segmental Treatment of Emphysema With Upper Lobe Predominance (STEP-UP) Study
Status: COMPLETED
Conditions: Emphysema
Interventions: DEVICE: InterVapor® treatment plus Optimal Medical Therapy|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Taping on Pulmonary Function and Forward Shoulder Posture FSP of Young Adults
Status: COMPLETED
Conditions: Healthy Young Adults
Interventions: OTHER: Kinesio Taping|OTHER: Conventional physiotherapy protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 3 Study of NI-071 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: NI-071|BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Autologous Serum Versus Preservative Free Artificial Tear
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: %40 diluted Autologous serum|DRUG: Preservative free artificial tears(Tears naturale free, Refresh single dose eye drop)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MWA vs RFA for the Treatment of Moderate-sized Benign Thyroid Nodules
Status: RECRUITING
Conditions: Thyroid Nodule \(Benign\)|Ablation Therapy
Interventions: PROCEDURE: Ablation treatment of thyroid nodule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroproprioceptive "Facilitation, Inhibition" and Brain Plasticity
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Motor program activating therapy|BEHAVIORAL: Vojta's reflex locomotion|BEHAVIORAL: Functional electric stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravesical BCG vs GEMDOCE in NMIBC
Status: RECRUITING
Conditions: Non-muscle-invasive Bladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Docetaxel|DRUG: Bacillus Calmette Guerin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study
Status: UNKNOWN
Conditions: Mitral Regurgitation
Interventions: DIAGNOSTIC_TEST: Cardiac MRI with or without contrast dye|DIAGNOSTIC_TEST: Blood sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of the Analgesic Effects of Intradermal and Subdermal Sterile Water Injection on Active Labor Pain
Status: NOT_YET_RECRUITING
Conditions: Labor Pain and to Reduce Pain
Interventions: OTHER: 0.9 NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and Frailty
Status: UNKNOWN
Conditions: Heart Failure, Systolic|Frailty
Interventions: DRUG: sacubitril/valsartan|DRUG: Angiotensin II Receptor Blockers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Navigation With X3 vs Non-Navigation With X3 Study
Status: COMPLETED
Conditions: Degenerative Joint Disease
Interventions: DEVICE: Trident X3 Insert with Navigation system|DEVICE: Trident X3 Insert with conventional instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance Investigation of a New 1-piece Ostomy Product Compared to Standard of Care 1-piece in Subjects With Ileostomy
Status: TERMINATED
Conditions: Ileostomy - Stoma
Interventions: DEVICE: Coloplast Test product|DEVICE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Thiamin Fortified Fish Sauce as a Means of Combating Infantile Beriberi in Rural Cambodia
Status: COMPLETED
Conditions: Thiamin Deficiency
Interventions: OTHER: Thiamin fortified fish sauce (low concentration)|OTHER: Thiamin fortified fish sauce (higher concentration)|OTHER: Placebo fish sauce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Tarceva
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SU006668 in Treating Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Breast Cancer|Colorectal Cancer|Gastric Cancer|Kidney Cancer|Lung Cancer|Multiple Myeloma and Plasma Cell Neoplasm|Pancreatic Cancer|Prostate Cancer
Interventions: DRUG: orantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Efficacy Of Intravenous Immunoglobulin Therapy In Treatment Induced Neuropathy Of Diabetes
Status: TERMINATED
Conditions: Diabetes Complications|Diabetes Mellitus|Diabetic Neuropathies
Interventions: DRUG: IGIV-C|DRUG: 0.9% Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Genomics in Practice (IGNITE): CYP2D6 Genotype-Guided Pain Management in Patients Undergoing Arthroplasty Surgery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: GENETIC: CYP2D6-guided opioid therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Naltrexone SR/ Bupropion SR in Overweight and Obese Subjects Who Are Nicotine-Dependent
Status: COMPLETED
Conditions: Nicotine Dependence|Overweight|Obesity
Interventions: DRUG: NB32|BEHAVIORAL: Ancillary therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ALG-010133|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19: Pediatric Research Immune Network on SARS-CoV-2 and MIS-C
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)|Multisystem Inflammatory Syndrome in Children (MIS-C)|Coronavirus Disease 2019 (COVID-19)
Interventions: OTHER: SARS-CoV-2 and/or MIS-C Exposure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Weekly Gemcitabine and Trastuzumab in the Treatment of Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytarabine and UCN-01 in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: 7-hydroxystaurosporine (UCN-01)|DRUG: Cytarabine (Ara-C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BIO-K + CL1285 in Prevention of Antibiotic-associated Diarrhea in Hospitalized Adult Patients
Status: COMPLETED
Conditions: Diarrhea|Clostridium Infections
Interventions: DIETARY_SUPPLEMENT: Lactobacillus acidophilus CL1285 and Lactobacillus casei|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Using Santyl or Bacitracin on Second Degree Burns
Status: WITHDRAWN
Conditions: Burn, Partial Thickness
Interventions: DRUG: Collagenase Santyl|BIOLOGICAL: Bacitracin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Chronic Knee Pain
Interventions: DEVICE: Radiofrequency Ablation|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: USS Virginia Closed-Loop Versus SAP Therapy for Hypoglycemia Reduction in T1D
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: AP System (DiAs or inControl) with USS Virginia|DEVICE: Sensor-Augmented Pump Therapy (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Fluticasone Furoate (FF)/GW642444 Inhalation Powder in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/GW642444 Inhalation Powder|DRUG: GW642444 Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT