pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SAvvyWire™ EFficacy and SafEty in Transcatheter Aortic Valve Implantation Procedures (SAFE-TAVI)
Status: COMPLETED
Conditions: Severe Aortic Stenosis
Interventions: DEVICE: TAVI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination of Osimertinib and Aspirin to Treat 1st Generation EGFR-TKI Resistance in NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer Stage IIIB|Non-small Cell Lung Cancer Stage IV|EGFR T790M
Interventions: DRUG: Osimertinib|DRUG: Aspirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics Study of DU-176b Administered to Patients With Severe Renal Impairment Undergoing Orthopedic Surgery of The Lower Limbs
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: 15mg DU-176b|DRUG: 30mg DU-176b|DRUG: Fondaparinux
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of AK104 in the First-line Treatment of Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: AK104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Reporting of Antibody-Drug Conjugate Associated Sepsis-related Toxicities
Status: COMPLETED
Conditions: Sepsis (SMQ)|Opportunistic Infections|Agranulocytosis
Interventions: DRUG: Antibody-Drug Conjugate|DRUG: Antineoplastic and immunomodulating agents other than Antibody-Drug Conjugate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Indian Gooseberry Extract (AMX160) in Hypercholesterolemia
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: AMX160|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-reported Outcomes in Neuroendocrine Neoplasms: a Prospective Quality of Life and Quality of Care Study Within NETwerk
Status: RECRUITING
Conditions: Quality of Life
Interventions: PROCEDURE: EORTC QLQ-C30|PROCEDURE: EORTC QLQ-GI.NET21|PROCEDURE: Satisfaction survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RGX-111 Gene Therapy in Patients With MPS I
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucopolysaccharidosis Type I (MPS I)|Hurler Syndrome|Hurler-Scheie Syndrome
Interventions: GENETIC: RGX-111
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium Augmentation for Hyperarousal Symptoms of Post Traumatic Stress Disorder: Pilot Study
Status: WITHDRAWN
Conditions: Combat Posttraumatic Stess Disorder|Mild Traumatic Brain Injury
Interventions: DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Premedication With Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis|Pain, Postoperative
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation of Bevacizumab With Ambulatory Blood Pressure Monitoring in Patients With Advanced Non-squamous NSCLC
Status: COMPLETED
Conditions: Advanced Non-squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Bevacizumab 7.5 mg/kg|DRUG: Bevacizumab 15 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Pharmacokinetics/-Dynamics of BIBT 986 BS in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBT 986 BS - low|DRUG: BIBT 986 BS - high|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Integrating HIV and Hepatitis C Screening in an Urban Emergency Department
Status: COMPLETED
Conditions: Hepatitis C|Hiv|HIV/AIDS|HCV Coinfection|HIV/AIDS and Infections
Interventions: OTHER: Bundled HCV/HIV Screening|OTHER: HIV Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety and Effectiveness Evaluation
Status: RECRUITING
Conditions: Mitral Valve Regurgitation
Interventions: DEVICE: Kalios Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral and Intravenous Ramosetron During Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Nausea|Vomiting|Laparoscopic Cholecystectomy
Interventions: DRUG: intravenous ramosetron|DRUG: oral ramosetron|DRUG: oral and IV ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dosing Study of Cranberry Capsules for the Prevention of Bacteriuria in Nursing Home Residents
Status: COMPLETED
Conditions: Bacteriuria
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Cranberry Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sequential Versus Simultaneous Pneumococcal Vaccination in Elderly: Immunological Memory and Antibody Levels
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: DRUG: PCV13|DRUG: PPV23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anodal Transcranial Direct Current Stimulation (tDCS) in the Treatment of Tobacco Addiction
Status: COMPLETED
Conditions: Addiction|Smoking
Interventions: PROCEDURE: sham tDCS|PROCEDURE: active tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravesical Instillations of Botulinum Toxin in TC-3 Gel in IC Patients
Status: COMPLETED
Conditions: Interstitial Cystitis|IC
Interventions: DEVICE: TC-3 Gel mixed with Botox (BTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases
Status: COMPLETED
Conditions: Breast Cancer|Brain Metastases
Interventions: DRUG: GRN1005|DRUG: Trastuzumab|DRUG: 18F-FLT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study in Participants With Chronic Lymphocytic Leukemia (CLL), Multiple Myeloma (MM) and Non-Hodgkin's Lymphoma (NHL) in Latin America
Status: COMPLETED
Conditions: Multiple Myeloma|Leukemia|Lymphoid|Lymphoma|Non-Hodgkin
Interventions: OTHER: Chronic Lymphocytic Leukemia (CLL)|OTHER: Multiple Myeloma (MM)|OTHER: Non-Hodgkin's lymphoma (NHL)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Human Papillomavirus Self-Collection on Cervical Cancer Screening in High Risk Women: My Body, My Test 3
Status: COMPLETED
Conditions: Cervical Cancer|Uterine Cervical Neoplasms|Human Papillomavirus
Interventions: BEHAVIORAL: Screening invitation (with education)|BEHAVIORAL: Self-collection for HPV testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Drug-coated Balloon Versus Drug-eluting Stent for de Novo Lesions in Large Coronary Arteries Guided by Optical Coherence Tomography
Status: UNKNOWN
Conditions: Angioplasty|Coronary Artery Disease
Interventions: DEVICE: DCB for de Novo Lesions in Large Coronary Arteries Guided by Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3016859 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY3016859 intravenous|DRUG: Placebo intravenous|DRUG: LY3016859 subcutaneous|DRUG: Placebo subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Budesonide vs. Mesalazine vs. Budesonide/Mesalazine Suppository Combination Therapy in Acute Ulcerative Proctitis
Status: COMPLETED
Conditions: Proctitis
Interventions: DRUG: Budesonide 2 mg suppository|DRUG: Budesonide 4 mg suppository|DRUG: Mesalazine 1 g suppository|DRUG: Budesonide 2 mg suppository/Mesalazine 1 g suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pirfenidone: A New Drug to Treat Kidney Disease in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Nephropathy
Interventions: DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Azacitidine, Lenalidomide, and Low-Dose Dexamethasone in Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: azacitidine|DRUG: lenalidomide|DRUG: dexamethasone|OTHER: DNA methylation analysis|OTHER: gene expression analysis|OTHER: bone marrow aspiration|OTHER: immunohistochemistry staining method|OTHER: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Assess the Efficacy and Safety of LCQ908 Alone and in Combination With Fenofibrate or Lovaza® in Patients With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Non Familial Chylocmicronemia Syndrome (Non-FCS)
Interventions: DRUG: LCQ908|DRUG: Fenofibrate|DRUG: Fish Oil|DRUG: Placebo of LCQ908|DRUG: Placebo of fenofibrate|DRUG: Placebo of fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Mechanical Axis With Soft Tissue Release Balancing vs Functional Alignment With Bony Release Balancing in Total Knee Replacement Using Stryker's Mako Robot
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: DEVICE: Triathlon® Total Knee System (Stryker Orthopaedics, Mahwah, NJ USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DETECT-IP: a Clinical Decision Support System and Intelligent Procedures to Counter Some Adverse Drug Events in Older Hospital Patients
Status: NOT_YET_RECRUITING
Conditions: Patient Acceptance of Health Care|Acute Renal Failure
Interventions: OTHER: Clinical decision support|OTHER: Will not receive Clinical Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 1b Study Evaluating OPomD in Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Immediate Release (IR) Formulation|DRUG: Gastro-Retentive (GR) Formulation|DRUG: Dexamethasone|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lead Migration in Spinal Cord Stimulation Trials: Comparing Non-suture vs Suture and Lead Anchor
Status: COMPLETED
Conditions: Spinal Cord Stimulation
Interventions: DEVICE: Suture|DEVICE: Lead Anchor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain
Status: COMPLETED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: Linaclotide 145 micrograms|DRUG: Linaclotide 290 micrograms|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact on French Physician's Haemophilia Treatment Management Decision Based on Systematic Joint Examination
Status: COMPLETED
Conditions: Hemophilia A
Interventions: PROCEDURE: Ultrasound, Haemophilia Joint Health Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Pemetrexed or Pemetrexed With Gemcitabine for Patients With Advanced Lung Cancer Who Are Not Eligible for Platinum-Based Chemotherapy and Have Not Previously Been Treated With Chemotherapy
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of CAL056 Mesylate in Patients With Resistant or Refractory Solid Tumors
Status: COMPLETED
Conditions: Resistant or Refractory Solid Tumors
Interventions: DRUG: CAL056 mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Herpetic Treatment of Genital Ulcer : Effect on HIV & Herpes Shedding (ANRS 1212)
Status: COMPLETED
Conditions: Ulcer|Herpes Genitalis
Interventions: DRUG: Acyclovir (ACV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy in Treating Patients With Non Small Cell Lung Cancer That Has Been Completely Removed by Surgery
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: OTHER: clinical observation|PROCEDURE: adjuvant therapy|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Study With Pretest/Posttest Groups Which the Intervention Group Have the System Which Sends Reminder Notifications Directing Them to the Website Containing BSE Training Along With the Illustrations Created for the Practice Prepared by the Researcher on the Determined Ideal Day
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Self-Examination|Breast Cancer|Nursing Caries|Cancer|Awakening Early
Interventions: OTHER: Early Diagnosis on BSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer
Status: RECRUITING
Conditions: Stage I Prostate Cancer AJCC v8|Stage II Prostate Cancer AJCC v8|Stage IIA Prostate Cancer AJCC v8|Stage IIB Prostate Cancer AJCC v8|Stage IIC Prostate Cancer AJCC v8
Interventions: RADIATION: High-Dose Rate Brachytherapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|PROCEDURE: Stereotactic Ablative Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma
Status: RECRUITING
Conditions: High Grade Sarcoma
Interventions: RADIATION: Intensity Modulated Radiation Therapy (IMRT)|DIAGNOSTIC_TEST: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lactobacillus Reuteri in Cystic Fibrosis
Status: COMPLETED
Conditions: CYSTIC FIBROSIS
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RC-48 Combined With GLS-010 in HER2-overexpressed Patients With Previously Treated Unresectable Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Carcinoma
Interventions: DRUG: Disitamab Vedotin combined with Zimberelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxyurea and Magnesium Pidolate to Treat People With Hemoglobin Sickle Cell Disease
Status: TERMINATED
Conditions: Hemoglobin SC Disease
Interventions: DRUG: Hydroxyurea|DRUG: Magnesium Pidolate|OTHER: Placebo Pills and Placebo Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Problem Management Plus (PM+) in Adult Syrian Refugees in Turkey: Pilot
Status: COMPLETED
Conditions: Anxiety|Depression|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Problem Management Plus (PM+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Efficiency of the Natural Preparation Rutan in Children in the Treatment of COVID-19, ARVI
Status: COMPLETED
Conditions: COVID-19 Respiratory Infection
Interventions: DRUG: Rutan 25 mg|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Behavior Therapy for Adults With Tourette Syndrome
Status: RECRUITING
Conditions: Tourette Syndrome|Chronic Tic Disorder
Interventions: BEHAVIORAL: Exposure with response prevention|BEHAVIORAL: Brief psychoeducation with general psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atazanavir and Endothelial Function in Older HIV Patients
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atazanavir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Commercial Scale SARS-CoV-2 Vaccine Against the Pilot Scale Among Adults, and Bridging Study of the Immunogenicity in Elderly Against That in Adults
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: Two doses of commercial scale inactivated SARS-CoV-2 vaccine at the schedule of day 0,14|BIOLOGICAL: Two doses of pilot scale inactivated SARS-CoV-2 vaccine at the schedule of day 0,14|BIOLOGICAL: Two doses of pilot scale inactivated SARS-CoV-2 vaccine at the schedule of day 0,14 in elderly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Finding Study to Treat Bone Tumor(s)
Status: RECRUITING
Conditions: Bone Cancer|Bone Tumor|Solid Tumor|Metastatic Cancer to the Bone|Metastatic Tumor to the Bone
Interventions: DRUG: 153-Sm-DOTMP (Samarium-153-DOTMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Colchicine|DRUG: Febuxostat|DRUG: SHR4640
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Reward Responses to Erythritol Using Flavor Preference Learning
Status: COMPLETED
Conditions: Reward Responses|Gastrointestinal Hormones|Glycemic Control|Appetite|Satiation|Emotional State
Interventions: DIETARY_SUPPLEMENT: Erythritol|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Sucralose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Contribution of Endothelin to Vasomotor Function in Diseased Coronary Arteries
Status: COMPLETED
Conditions: Atherosclerosis, Coronary
Interventions: DRUG: Drug Infusion (BQ-123)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase III Study to Evaluate Safety and Efficacy of Ilaprazole in Patients With NERD
Status: COMPLETED
Conditions: Non-erosive Reflux Disease
Interventions: DRUG: Ilaprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Safety of a New Wound Dressing in the Local Treatment of Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer(s)
Interventions: DEVICE: Urgo 310 3113|DEVICE: Placebo URGO 310 3113 dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effects of Camoteskimab in Adults With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis|Atopic|Dermatitis|Dermatologic Disease|Eczema|Eczema Atopic Dermatitis|Eczema, Atopic
Interventions: DRUG: Camoteskimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Single and Multiple Intravenous Doses of Finafloxacin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Finafloxacin i.v. solution 200 mg|DRUG: Finafloxacin i.v. solution 400 mg|DRUG: Finafloxacin i.v. solution 600 mg|DRUG: Finafloxacin i.v. solution 800 mg|DRUG: Finafloxacin i.v. solution 1000 mg|DRUG: Placebo i.v. solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Adjuvant Radiotherapy in Breast Cancer Using a Once a Week Hypofractionated Regimen
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: RADIATION: once-weekly breast irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Level and Insomnia
Status: ENROLLING_BY_INVITATION
Conditions: Primary Dysmenorrhea
Interventions: DIAGNOSTIC_TEST: WaLIDD score / Insomnia Severity Index (ISI) / International Physical Activity Questionnaire (Short-form) / Six-Minute Walk Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of L-arginine Supplementation in Adults With Moderate to Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: L-arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Treatment Strategy Based on for Pediatric AML
Status: UNKNOWN
Conditions: Pediatric Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Mitoxantrone|DRUG: Etoposide|PROCEDURE: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
Status: RECRUITING
Conditions: Primary Prevention of Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL|DRUG: Placebo in 1.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Study, Comparing Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy, Versus Multiple Inhaler Therapy (Budesonide/Formoterol Plus Tiotropium) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: budesonide/formoterol|DRUG: albuterol/salbutamol|DRUG: FF/UMEC/VI|DRUG: Placebo to match budesonide/formoterol|DRUG: tiotropium|DRUG: Placebo to match FF/UMEC/VI|DRUG: placebo to match tiotropium|DEVICE: ELLIPTA|DEVICE: MDI|DEVICE: HandiHaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Inflammation in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer's Disease
Interventions: DRUG: 11C-PBR28|DRUG: 18F-Florbetaben|PROCEDURE: Lumbar puncture (optional)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Automatic Oxygen Administration During the Respiratory Distress in Infants and Children (Infant-FreeO2)
Status: COMPLETED
Conditions: Hypoxemic Acute Respiratory Distress|Infant Between 1 Month and 24 Months Old|Child Between 2 and 15 Years Old
Interventions: DEVICE: FreeO2 v2.0 automatic adjustment|DEVICE: FreeO2 v2.0 data collecting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Acupuncture Care for Breast Cancer Patients Experiencing Side Effects From Chemotherapy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: PROCEDURE: Acupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HYDEAL-D® Application for Promoting the Restoration of Sexual Function in the Postpartum Period
Status: COMPLETED
Conditions: Vagina; Anomaly|Puerperium; Disease|Sexual Dysfunction
Interventions: DRUG: Vaginal gel HYALOGYN®|BEHAVIORAL: Expectant management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact and Neuro-functional Substrate of Immersive Virtual Reality Sports Practice on Depression
Status: UNKNOWN
Conditions: Depression
Interventions: OTHER: Physical training|OTHER: Virtual reality|DEVICE: Single-photon emission computed tomography (SPECT)|BIOLOGICAL: Metabolomics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Maternal and Neonatal Benefits of Prophylactic Administration of Vitamin K Before Elective Cesarean Section
Status: COMPLETED
Conditions: Vitamin K
Interventions: DIETARY_SUPPLEMENT: vitamin k
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study of Infusional Paclitaxel With the P-Glycoprotein Antagonist PSC 833
Status: COMPLETED
Conditions: Breast Cancer|Cancer|Carcinoma, Renal Cell|Lymphoma|Ovarian Cancer
Interventions: DRUG: PSC 833|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Energy Balance Study
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Low carbohydrate diet|OTHER: High-carbohydrate ad libitum intervention|OTHER: High carbohydrate diet-energy matched intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Acquired Brain Injury|Disorder of Consciousness
Interventions: DEVICE: ErigoBasic or ErigoPro®|BEHAVIORAL: Traditional Verticalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Narcotic Use After Minor Hand Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Minor Surgical Procedures|Narcotics Use
Interventions: BEHAVIORAL: Initial prescription for 10 narcotic tabs|BEHAVIORAL: Inital prescription for 30 narcotic tabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of Pertuzumab Given in Combination With Trastuzumab and Vinorelbine in Participants With Metastatic or Locally Advanced Human Epidermal Growth Factor Receptor (HER) 2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a 12-week Movement Intervention on Heart Rate Variability and Self-compassion Among New Mothers
Status: COMPLETED
Conditions: Pregnancy Related
Interventions: BEHAVIORAL: Yoga movement intervention|OTHER: Education booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: PROCEDURE: conventional surgery|PROCEDURE: magnetic resonance imaging|PROCEDURE: magnetic resonance spectroscopic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant
Status: UNKNOWN
Conditions: Polyomavirus Infections|BK Viremia|Liver Transplant Infection|Kidney Transplant Infection
Interventions: PROCEDURE: Simultaneous Liver-Kidney Transplant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acceptance and Performance of CP1110 Sound Processor With Experienced Adult Cochlear Implant Recipients.
Status: COMPLETED
Conditions: Adult Cochlear Implant Recipients
Interventions: DEVICE: CP1110 Sound Processor System|DEVICE: Nucleus 7 Sound Processor (model: CP1000) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Docetaxel/Cisplatin/5-fluorouracil (TPF) as Selector for Chemo Radiation Therapy (RT) Versus Partial Laryngectomy in Advanced Laryngeal Cancer
Status: UNKNOWN
Conditions: Larynx Cancer
Interventions: PROCEDURE: laryngoscopy|DRUG: Taxotere (Docetaxel), Cisplatin, 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BOTOX® Economic Spasticity Trial (BEST)
Status: COMPLETED
Conditions: Muscle Spasticity
Interventions: BIOLOGICAL: Botulinum Toxin Type A 900kD|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intensive Aphasia Therapy Under Routine Clinical Conditions
Status: COMPLETED
Conditions: Aphasia|Stroke
Interventions: BEHAVIORAL: Intensive integrative aphasia therapy|BEHAVIORAL: Waiting list control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Pioglitazone 45 mg|DRUG: Empagliflozin 25 MG|DRUG: Semaglutide 7 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study Comparing Two Different Anti-HIV Drug Combinations in HIV-Positive Patients Without Previous Anti-HIV Drug Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Use of an Engineered Glove for the Assessment and Rehabilitation of Manual Dexterity in People With Stroke.
Status: UNKNOWN
Conditions: Stroke|Hand Grasp
Interventions: OTHER: experimental group|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial for the Earlier Diagnosis of Inferior Wall STEMI Using a Six-lead Handheld EKG Recorder
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction|Electrocardiogram
Interventions: DIAGNOSTIC_TEST: KardiaMobile 6L
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: BIOLOGICAL: Recombinant Activated Factor VII (rFVIIa)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Deep Serratus Anterior Plane Block and Combination of Deep and Superficial Serratus Anterior Plane Block
Status: COMPLETED
Conditions: Pain, Postoperative|Serratus Anterior Plane Block|Multimodal Analgesia|Thoracic Surgery, Video-Assisted
Interventions: PROCEDURE: Deep block and Combined Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Advanced Self- Adhesivee Resin Composite Hybrid Restorations.
Status: UNKNOWN
Conditions: Caries Class II|Caries,Dental
Interventions: OTHER: Advanced Self-Adhesive resin composite hybrid restorations (Surefil one (Dentsply Sirona)).|OTHER: Conventional resin composite restoration. (Sphere Tec, (Dentsply Sirona
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Trial of BMS-690514 in Combination With FOLFIRI and FOLFOX
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: BMS-690514 / FOLFIRI|DRUG: BMS-690514 / FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Interventions for Primary Care Patients With Stress-related Ill-health: a Non-inferiority RCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress
Interventions: BEHAVIORAL: Care manager intervention (nurse)|BEHAVIORAL: CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Wall Motion Analysis in Disease
Status: COMPLETED
Conditions: Mesothelioma|Lung Neoplasms|Surgery|Cystic Fibrosis|Pectus Carinatum|Pectus Excavatum|Empyema, Pleural|Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Chest wall motion analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Participants With B-cell Malignancies
Status: ENROLLING_BY_INVITATION
Conditions: B-cell Malignancies
Interventions: DRUG: Zanubrutinib|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy and Anxiety Study
Status: RECRUITING
Conditions: Anxiety Related to Pain Related to an Intraarticular Injection|Pain Related to an Intraarticular Injection
Interventions: BEHAVIORAL: Guided Meditation|OTHER: Aromatherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Robotic vs. Laparoscopic Distal Pancreatectomy for Pancreatic Cancer
Status: WITHDRAWN
Conditions: Pancreatic Tumor
Interventions: PROCEDURE: Robot-assisted distal pancreatectomy|PROCEDURE: Laparoscopic distal pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emulsification of Different Viscosity Silicone Oil After Complicated Retinal Detachment Surgery
Status: COMPLETED
Conditions: Retinal Detachment Rhegmatogenous
Interventions: DEVICE: Surgery using low viscosity silicone oil|DEVICE: Surgery using high viscosity silicone oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oesogastroduodenoscopy With Vision to 245 ° (Full Spectrum Endoscopy) to View the Main Disc and Accessory
Status: COMPLETED
Conditions: Adenoma of the Accessory Papilla|Ampulloma of the Accessory Papilla
Interventions: DEVICE: gastroscope FUSE™
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validating TEE Measurements of Right Ventricular Function
Status: COMPLETED
Conditions: Ventricular Function, Right|Echocardiography, Transesophageal
Interventions: DIAGNOSTIC_TEST: Transesophageal Echocardiography|DIAGNOSTIC_TEST: Transthoracic Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of a DNA-based Venezuelan Equine Encephalitis Virus DNA Vaccine Administered by Electroporation in Healthy Volunteers
Status: COMPLETED
Conditions: Venezuelan Equine Encephalitis Virus Infection
Interventions: BIOLOGICAL: Venezuelan Equine Encephalitis Virus DNA Vaccine Candidate|OTHER: 0.9% saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Using Specific Tests in Preschool Children With Wheeze to Help us Determine the Necessity of Inhaled Corticosteroid Therapy (Feasibility Study).
Status: ACTIVE_NOT_RECRUITING
Conditions: Wheezing
Interventions: DIAGNOSTIC_TEST: Blood eosinophil count|DIAGNOSTIC_TEST: Atopic sensitization|DIAGNOSTIC_TEST: FeNO (offline method)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-oral Camera in Gingival Health
Status: COMPLETED
Conditions: Gingival Hemorrhage|Gingivitis|Health Behavior|Communication
Interventions: BEHAVIORAL: SPT consultation|DEVICE: SOPROCARE®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Dynamics in Bone Turnover Markers During and After Short-term Glucocorticoid Treatment in Patients With an Inflammatory Joint Disease
Status: NOT_YET_RECRUITING
Conditions: Osteoporosis|Osteoporosis, Steroid Induced|Inflammatory Rheumatism
Interventions: DRUG: Glucocorticoid Effect
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Home-Monitoring in Implantable Cardioverter Defibrillator (ICD) Patients
Status: UNKNOWN
Conditions: Ventricular Arrythmias
Interventions: DEVICE: Home-monitoring provided by LUMAX ICD device and CardioMessenger II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal vs. IV Dexmedetomidine in Endoscopic Sinus Surgery
Status: RECRUITING
Conditions: Functional Endoscopic Sinus Surgery|Dexmedetomidine
Interventions: DRUG: intranasal dexmedetomidine group|DRUG: intravouns dexmedetomidine group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Risk Metachronous Oligometastatic Prostate Cancer Trial
Status: RECRUITING
Conditions: Prostate Cancer|Oligometastatic Disease
Interventions: DRUG: niraparib/abiraterone acetate|RADIATION: Stereotactic ablative radiation therapy (SABR)|DRUG: Androgen deprivation therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Envafolimab, Lenvatinib Combined With VP-16 in Platinum-resistant Recurrent Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer, Epithelial
Interventions: DRUG: Envafolimab|DRUG: Lenvatinib|DRUG: VP-16
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abuse Potential Study of PF-00345439
Status: COMPLETED
Conditions: Opioid Users
Interventions: DRUG: Capsule|DRUG: PF-00345439|DRUG: PF-00345439|DRUG: oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Cilta-cel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influenza Vaccination, ACEI and ARB in the Evolution of SARS-CoV2 Infection
Status: RECRUITING
Conditions: COVID19|Influenza Vaccination|ACE Inhibitors|ARB|Antihistamine Allergy|Amantadine
Interventions: DRUG: Antihistamine|DRUG: Amantadine|DRUG: ACEI|DRUG: ARB|OTHER: Influenza vaccine and COVID
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deflazacort vs. Prednisolone in Acute-stage ABPA
Status: ACTIVE_NOT_RECRUITING
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Deflazacort|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tucidinostat Plus PD-1 Inhibitor and Bevacizumab for Advanced Esophagus Cancer, AEG, Gastric Cancer
Status: RECRUITING
Conditions: Esophageal Squamous Cell Cancer, Adenocarcinoma of Esophagogastric Junction, Gastric Adenocarcinoma
Interventions: DRUG: Tucidinostat (chidamide), PD-1 inhibitor (Toripalimab), Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Mobilization on SAH Patients Physiological Parameters
Status: NOT_YET_RECRUITING
Conditions: Subarachnoid Hemorrhage
Interventions: DEVICE: lung ultrasound|DEVICE: Transcranial Doppler|DEVICE: near-infrared spectroscopy (NIRS)|DEVICE: clinical examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Self and Body Perception in Otoneurological Disorders: Translation and Validation of Measurement Scales
Status: UNKNOWN
Conditions: Patients With Acute or Chronic Otoneurological Disorders|Patients Presenting or Having Experienced Dizziness and / or Balance Disorders
Interventions: OTHER: Questionnaire Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.
Status: NOT_YET_RECRUITING
Conditions: Patellofemoral Osteoarthritis
Interventions: BIOLOGICAL: Engineered cartilage graft (N-TEC)|PROCEDURE: Autologous Matrix Induced Chondrogenesis (AMIC)|PROCEDURE: Patellofemoral Arthroplasty (PFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate Safety and Performance of NeuRx DPS in Patients Undergoing Bilateral Lung Transplantation
Status: COMPLETED
Conditions: Chronic Obstructive Airway Disease
Interventions: DEVICE: NeuRx Diaphragm Pacing System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine in Combination With Bortezomib and Pegylated Liposomal Doxorubicin for Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Bendamustine|DRUG: Doxorubicin|DRUG: Bortezomib|DRUG: Bendamustine|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT