pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Safety & Efficacy for the Prevention of Ocular GVHD With Ophthalmic Tacrolimus vs Cyclosporine in Allo-HSCT
Status: RECRUITING
Conditions: Ocular Graft-versus-host Disease
Interventions: DRUG: Cyclosporine ophthalmic solution 0.1%|DRUG: Tacrolimus ophthalmic ointment 0.03%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis|Frontotemporal Dementia|PLS|Motor Neuron Disease|Lou Gehrigs Disease|Familial Disease|Amyotrophic Lateral Sclerosis, Sporadic|Muscular Dystrophy|Miyoshi Myopathy|Amyotrophic Lateral Sclerosis With Dementia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Velcade and Lenalidomide in Patients With Relapsed AML and MDS After Allogeneic Stem Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndrome|Acute Myeloid Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Cerebral Motor Activity Modulations Following Median Nerve Stimulation During General Anaesthesia
Status: RECRUITING
Conditions: Accidental Awareness During General Anesthesia
Interventions: DRUG: Propofol|DEVICE: Median nerve stimulation|DEVICE: EEG measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986166 in Healthy Japanese Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986166|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Clinical Encounter to Enhance Delivery of an Individualized Prematurity Prevention Plan
Status: COMPLETED
Conditions: Preterm Birth
Interventions: BEHAVIORAL: Intervention Arm Weekly IP3 text messages|OTHER: Active Control Arm General pregnancy text messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of a New Chemotherapy Agent to Treat Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Histone Deacetylase Inhibitor, MS-275 (BAY 86-5274, ZK 244894)|DRUG: Histone Deacetylase Inhibitor, MS-275 (BAY 86-5274, ZK 244894)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of PRISMA for Prisoners in Switzerland
Status: RECRUITING
Conditions: Psychological Distress|Anxiety|Depression|Suicidal Ideation
Interventions: BEHAVIORAL: PRISMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Iron Supplementation During Darbepoetin Alfa Treatment in Prophylaxis of Severe Anaemia Chemo-Induced
Status: TERMINATED
Conditions: Neoplasms|Anemia
Interventions: DRUG: Darbepoetin alfa (Aranesp®)|DRUG: Ferric saccharose(Venofer®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: US-guided Pericapsular Nerve Group (PENG) Block in Different Volumes on Postoperative Pain in Hip Replacement Surgeries
Status: RECRUITING
Conditions: Regional Anesthesia|Postoperative Pain|Hip Surgery
Interventions: DRUG: PENG block with 0.25% bupivacaine.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Modified "Open Intraperitoneal Mesh" Technique of Incisional Ventral Hernia Repair
Status: COMPLETED
Conditions: Incisional Ventral Hernia|Recurrent Ventral Hernia
Interventions: PROCEDURE: modified "open mesh technique"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Lozenges as Preventative Care in Low-grade Dysplasia
Status: WITHDRAWN
Conditions: Low-grade Oral Dysplasia
Interventions: BIOLOGICAL: Probiotic oral lozenges|OTHER: Standard of care for oral dysplasia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dendritic Cell/Myeloma Fusion Vaccine for Multiple Myeloma (BMT CTN 1401)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Tumor Cell Collection|PROCEDURE: Autologous Stem Cell Transplant|DRUG: Melphalan|PROCEDURE: Leukapheresis|BIOLOGICAL: Myeloma vaccine|DRUG: GM-CSF|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of ExAblate MRI Guided High Intensity Focused Ultrasound Tx of Soft Tissue Tumors
Status: TERMINATED
Conditions: Soft Tissue Neoplasms
Interventions: DEVICE: MRgHIFU|DRUG: Aspirin|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions
Status: RECRUITING
Conditions: Autoimmune Diseases|Cardiovascular Disorders|Diabetes Complications|Integumentary Disease|Musculoskeletal Disorders|Neurodegenerative Disorders|Neurologic Disorders|Pulmonary Disorders|Sexual Dysfunction|Urologic Disorders|Viral Illness
Interventions: BIOLOGICAL: PrimePro™/ PrimeMSK™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Various Diets on Surgical Complications
Status: UNKNOWN
Conditions: Complication,Postoperative
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|DIETARY_SUPPLEMENT: High-protein|DIETARY_SUPPLEMENT: Standard ONS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Survival of Recombinant Human Neuregulin-1β in Chronic Heart Failure (CHF) Patients
Status: TERMINATED
Conditions: Chronic Heart Failure
Interventions: DRUG: rhNRG-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics/Pharmacodynamics (PK/PD) of Fluconazole in Children on Extracorporeal Membrane Oxygenation (ECMO)
Status: COMPLETED
Conditions: Cardiopulmonary Arrest|Fungal Infection
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Westlake N-of-1 Trials for Macronutrient Intake
Status: COMPLETED
Conditions: Postprandial Hyperglycemia|Metabolic Disorder, Glucose
Interventions: OTHER: High fat low carbohydrate diet|OTHER: Low fat high carbohydrate diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aldosterone in Diabetic Nephropathy
Status: UNKNOWN
Conditions: Diabetic Nephropathy
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Isatuximab in Combination With Novel Agents in RRMM - Master Protocol
Status: RECRUITING
Conditions: Plasma Cell Myeloma Refractory
Interventions: DRUG: Isatuximab|DRUG: Dexamethasone|DRUG: Pomalidomide|DRUG: Belantamab mafodotin|DRUG: Pegenzileukin|DRUG: SAR439459|DRUG: Belumosudil|DRUG: Evorpacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Maturity-Onset Diabetes of the Young, Type 2|MODY2|Insulin Resistance
Interventions: DRUG: Hyperinsulinemic, euglycemic clamp|DRUG: 20% dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-451840 10 mg|DRUG: ACT-451840 50 mg|DRUG: ACT-451840 200 mg|DRUG: ACT-451840 500 mg|DRUG: ACT-451840 1000 mg|DRUG: ACT-451840 (Dose to be determined)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Immunogenicity and Safety of VARIVAX™ New Seed Process (NSP) in Children (V210-063)
Status: COMPLETED
Conditions: Varicella
Interventions: BIOLOGICAL: VARIVAX™ New Seed Process|BIOLOGICAL: VARIVAX™ 2007 process|BIOLOGICAL: M-M-R II™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of C-Scan System in Providing Structural Information and Detection of Polypoid Lesions in High Risk Subjects
Status: COMPLETED
Conditions: High Risk (Above Average) Subjects|Non Compliant Patients for Colo Rectal Cancer [CRC] Screening|Counterindicated Patients for Colonoscopy
Interventions: DEVICE: C-Scan System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: An [^11C]T-773 Positron Emission Tomography (PET) Study to Determine Phosphodiesterase10A Occupancy by TAK-063
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-063|DRUG: [^11C]T-773
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) in Acute Manic Episodes Associated With Bipolar I Disorder
Status: TERMINATED
Conditions: BIPOLAR I DISORDER
Interventions: DRUG: Eslicarbazepine acetate 1800 mg|DRUG: Eslicarbazepine acetate 1200 mg|DRUG: Eslicarbazepine acetate 600 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Follow up of Minimally Invasive Chest Wall Surgery After Trauma
Status: COMPLETED
Conditions: Rib; Fracture, Multiple, With Flail Chest
Interventions: PROCEDURE: Minimally invasive surgical fixation of unstable rib cage|PROCEDURE: Large incision surgical fixation of unstable rib cage.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Graded Motor Imagery in Women Diagnosed With Genito-Pelvic Pain Penetration Disorder
Status: COMPLETED
Conditions: Genito-Pelvic Pain/Penetration Disorder
Interventions: OTHER: Graded Motor Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ranibizumab 0.5 vs Verteporfin PDT in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
Status: COMPLETED
Conditions: Visual Impairment Due to Choroidal Neovascularization (CNV) Secondary to Pathologic Myopia (PM)
Interventions: DRUG: Ranibizumab 0.5mg|DRUG: Ranibizumab 0.5 mg|DRUG: Verteporfin PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using tDCS in Speech-based Stroke Rehabilitation
Status: RECRUITING
Conditions: Apraxia of Speech
Interventions: DEVICE: Soterix 1x1 line tDCS low-intensity stimulator|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Chronic Non-Specific Neck Pain And Lumbar Reposition Sense
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Non-specific Neck Pain
Interventions: DIAGNOSTIC_TEST: Chronic non-specific neck pain and lumbar reposition sense
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Iron Absorption Trial
Status: COMPLETED
Conditions: Iron Absorption|Bariatric Surgery|Roux- en -y Gastric Bypass
Interventions: DRUG: Ferrous fumarate|DRUG: Ferrous gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation
Status: TERMINATED
Conditions: Opioid-Induced Constipation
Interventions: DRUG: CB-5945|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics and Efficacy Study of Bisthianostat in Refractory or Recurrent Multiple Myeloma Patients
Status: UNKNOWN
Conditions: Refractory Multiple Myeloma|Recurrent Multiple Myeloma
Interventions: DRUG: Bisthianostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Biphasic Human Insulin Compared to EX1000 in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: EX1000|DRUG: biphasic human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Time Restricted Eating (TRE) Among Native Hawaiian/Pacific Islander Women at Risk for Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Neoplasms
Interventions: BEHAVIORAL: Time Restricted Eating (TRE) Schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trunk Position Sense, Postural Stability and Spinal Posture in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Postural Lordosis|Postural Kyphosis|Proprioception|Postural Stability|Balance
Interventions: OTHER: Evaluation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer
Status: COMPLETED
Conditions: Central Nervous System Metastases|Leptomeningeal Metastases|Recurrent Breast Cancer|Stage IV Breast Cancer|Tumors Metastatic to Brain
Interventions: DRUG: methotrexate|DRUG: liposomal cytarabine|OTHER: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Stress Management and Resilience Among Individuals With Von Hippel- Lindau Disease
Status: ENROLLING_BY_INVITATION
Conditions: Von Hippel-Lindau Disease|Genetic Disorder
Interventions: BEHAVIORAL: 3RP-VHL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The KOMOtini BONE Study: Evaluation of the Osteogenic Potential of Sports
Status: UNKNOWN
Conditions: Bone Mineral Content|Bone Density|Bone Turnover Markers|Athletic Performance
Interventions: OTHER: School physical education class|OTHER: Taekwondo|OTHER: Martial arts|OTHER: Climbing|OTHER: Volleyball|OTHER: Artistic gymnastics|OTHER: Swimming|OTHER: Dance|OTHER: Basketball|OTHER: Wrestling|OTHER: Football (soccer)|OTHER: Rhythmic gymnastics|OTHER: Track and field|OTHER: Tennis|OTHER: Combination of activities 1|OTHER: Combination of activities 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: AVEIR DR Coverage With Evidence Development (CED) Study
Status: RECRUITING
Conditions: Cardiac Pacemaker|Arrythmia|Bradycardia
Interventions: DEVICE: Aveir DR Leadless Pacemaker System|DEVICE: Dual Chamber Transvenous Pacemaker
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Estradiol Transdermal Spray in the Treatment of Vasomotor Symptoms
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Estradiol transdermal one 90 μL spray|DRUG: Estradiol transdermal spray, two 90 μL sprays|DRUG: Estradiol transdermal three 90 μL sprays|DRUG: Placebo transdermal two 90 μL sprays|DRUG: Placebo transdermal three 90 μL sprays|DRUG: Placebo transdermal one 90 μL spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CIN-107 in Patients With Uncontrolled Hypertension
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: DRUG: CIN-107|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water Versus Saline as Irrigation Fluid for Ureteroscopy
Status: COMPLETED
Conditions: Ureteral Stricture|Hydronephrosis|Urothelial Carcinoma|Urolithiasis
Interventions: OTHER: Water|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Investigator Initiated Trial to Evaluate Cartilage Regeneration by Arthroscopy After JOINTSTEM Administration
Status: NOT_YET_RECRUITING
Conditions: Degenerative Arthritis|Knee Arthritis
Interventions: BIOLOGICAL: JOINTSTEM|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SAMURAI-NVAF Study: Anticoagulant Therapy for Japanese Stroke Patients With Nonvalvular Atrial Fibrillation (NVAF)
Status: UNKNOWN
Conditions: Stroke, Acute|Atrial Fibrillation
Interventions: OTHER: This is an observational study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Jaktinib Dihydrochloride Monohydrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: refined indigo naturalis ointment|DRUG: crude indigo naturalis ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of Pumosetrag in Patients With Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Pumosetrag|DRUG: Pumosetrag|OTHER: Placebo|DRUG: Pumosetrag
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Safety, Feasibility and Effect of TTFields (200 kHz) Concomitant With Weekly Paclitaxel in Recurrent Ovarian Carcinoma (INNOVATE)
Status: UNKNOWN
Conditions: Ovarian Carcinoma
Interventions: DEVICE: NovoTTF-100L(O)|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide or Selumetinib in Treating Patients With Metastatic Melanoma of the Eye
Status: COMPLETED
Conditions: Iris Melanoma|Medium/Large Size Posterior Uveal Melanoma|Ocular Melanoma With Extraocular Extension|Recurrent Uveal Melanoma|Small Size Posterior Uveal Melanoma|Stage IV Uveal Melanoma
Interventions: DRUG: Dacarbazine|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Selumetinib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steady-state Pharmacokinetics of BIA 2-093 and Oxcarbazepine in Healthy Volunteers
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Treatment-resistant Depression: A Multicentric Clinical Trial in Mexican Population
Status: UNKNOWN
Conditions: Depressive Disorder,|Treatment-Resistant Depression
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Results of 2 Laparoscopic Surgical Procedures in Operable Colon Cancer Cases in Upper Egypt
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer Stage I|Colon Cancer Stage II
Interventions: PROCEDURE: laparoscopic conventional colectomy|PROCEDURE: laparoscopic complete mesocolic excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Nebulized and Intravenous Hypertonic Saline 3% on the Management of Patients With Acute Respiratory Distress Syndrome
Status: RECRUITING
Conditions: Nebulization|Hypertonic Saline|Acute Respiratory Distress Syndrome
Interventions: DRUG: Hypertonic saline 3% nebulizer|DRUG: Intravenous hypertonic saline 3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled Evaluation of Increasing Doses of Weekly Tafenoquine for Chemosuppression of Plasmodium Falciparum
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Placebo|DRUG: Tafenoquine 25mg|DRUG: Tafenoquine 50mg|DRUG: Tafenoquine 100 mg|DRUG: Tafenoquine 200 mg|DRUG: Mefloquine 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PillCam® Colon 2 Capsule Endoscopy Regimen
Status: COMPLETED
Conditions: Colonoscopy|Endoscopy
Interventions: OTHER: PillCam® COLON 2 procedure using MgC boosts|OTHER: PillCam® COLON 2 procedure using Suprep boosts|OTHER: PillCam® COLON 2 procedure using reduced dose of Suprep boosts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transvaginal Ultrasound Cervical Length Screening in Singleton Pregnancy Without Prior Spontaneous Preterm Birth
Status: WITHDRAWN
Conditions: Preterm Birth
Interventions: OTHER: TVU CL screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Multicenter, Randomized, Double Blind, Double Dummy, Parallel-Group Efficacy Study Comparing 8 Weeks of Treatment With Esomeprazole Magnesium (40mg qd) to Lansoprazole (30mg qd) for the Healing of Erosive Esophagitis in Patients With Moderate or Severe Erosive Esophagitis
Status: COMPLETED
Conditions: Erosive Esophagitis
Interventions: DRUG: Esomeprazole|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Statin Use in Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DRUG: Atorvastatin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Managing Non-acute Low Back Symptoms in Occupational Health: Two Trials
Status: UNKNOWN
Conditions: Low Back Pain, Recurrent|Low Back Pain
Interventions: OTHER: Moderate|OTHER: Mild|OTHER: Mild vs. NC|OTHER: Moderate vs. NC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PD-1 Combined With Dasatinib for as Third-line Treatment for ARID1A Mutation Advanced NSCLC
Status: UNKNOWN
Conditions: NSCLC Stage IV|ARID1A|PD-1
Interventions: DRUG: PD-1 plus Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients
Status: COMPLETED
Conditions: Postoperative Kidney Injury
Interventions: DRUG: human albumin 5%|DRUG: HES 130/0.4 (Voluven)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Bicarbonate in Addition to Theophylline Reduce CIN?
Status: COMPLETED
Conditions: Radiographic Contrast Agent Nephropathy
Interventions: OTHER: Hydration with bicarbonate in addition to theophylline|OTHER: Hydration with sodium chloride in addition to theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Muscle Derived Cells Female Stress Urinary Incontinence Clinical Study
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: BIOLOGICAL: AMDC-USR|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate INCA033989 Administered in Participants With Myeloproliferative Neoplasms
Status: RECRUITING
Conditions: Myeloproliferative Neoplasms
Interventions: DRUG: INCA033989
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 3 Week vs 6 Week Orthodontic Appointment Intervals on Teeth Alignment
Status: RECRUITING
Conditions: Orthodontic Tooth Movement|Tooth Alignment
Interventions: PROCEDURE: tooth alignment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccination for Patients With Acute Myeloid Leukemia in Remission
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: BIOLOGICAL: injection of antigen-loaded cultured dendritic cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial
Status: UNKNOWN
Conditions: Optic Neuritis|Treatment|Methylprednisolone
Interventions: DRUG: Methylprednisolone Acetate 40 MG/ML [Depo-Medrol]|DRUG: Placebo Comparator: Standard treatment + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of NMDA-enhancing and Anti-inflammatory Treatments for Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: NMDAE plus AIFA|DRUG: NMDAE plus Placebo Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating ACC-001 In Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: BIOLOGICAL: ACC-001 + QS-21|BIOLOGICAL: QS-21|OTHER: Diluent: Phosphate Buffered Saline|BIOLOGICAL: ACC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Recording and Stimulating Array Brain-Machine Interface
Status: RECRUITING
Conditions: Tetraplegia|Spinal Cord Injury|Brainstem Stroke|Brachial Plexus Injury|Above Elbow Amputation
Interventions: DEVICE: Implantation of CRS Arrays
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuro-muscular Exercise Training Verses Quadriceps Training in Mild to Moderate Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Neuro-muscular exercise training Group|OTHER: quadriceps training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of Pegamotecan (PEG-Camptothecin) in Localized or Metastatic Cancer of the Stomach or Gastroesophageal Junction
Status: TERMINATED
Conditions: Cancer of Stomach|Gastroesophageal Cancer
Interventions: DRUG: Pegamotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Mobilization in Older Adults With Acute Cardiovascular Disease
Status: WITHDRAWN
Conditions: Early Mobilization|Older Adults|Acute Cardiovascular Disease|Nursing
Interventions: BEHAVIORAL: Early Mobilization|BEHAVIORAL: Usual Mobility Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMT in Ulcerative Colitis-Associated Pouchitis
Status: COMPLETED
Conditions: Ulcerative Colitis Associated Pouchitis
Interventions: BIOLOGICAL: biologically active human fecal microbiota|PROCEDURE: sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triple Negative Breast Cancer: Identification Pilot Study of Predictive Transcriptome Profiles of Early Tumor Drug Resistance Observed in 18F-Fluorodeoxyglucose (FDG) PET
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: OTHER: PET with FDG|OTHER: Tumor exome analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0031 to Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: sNN0031|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Targeting of Cluster of Differentiation 52 (CD52) and Tumor Necrosis Factor (TNF) Allows Early Minimization Therapy in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: MabCampath,|DRUG: Remicade|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Prospective Study Comparing Extended With Limited Pelvic Lymphadenectomy in Intermediate and High Risk Prostate Cancer Patients Undergoing Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Prostate Cancer, Genetic Risk, and Equitable Screening Study (ProGRESS)
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: GENETIC: Precision screening intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease-modifying Anti-rheumatic Drugs
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriatic Arthritis
Interventions: DRUG: Deucravacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Efficacy and Safety of Ingenol Mebutate 0.05% Gel for Common Warts on the Hands.
Status: COMPLETED
Conditions: Verruca Vulgaris|Common Warts
Interventions: DRUG: ingenol mebutate 0.05% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Vascular Disease|Pulmonary Artery Hypertension|Chronic Thromboembolic Pulmonary Hypertension
Interventions: BEHAVIORAL: Relocation to sea level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Thoracic Block Technique on Atelectasis in Children on Mechanical Ventilation
Status: COMPLETED
Conditions: Atelectasis|Intensive Care Unit|Children
Interventions: OTHER: Thoracic block technique|OTHER: Designed chest physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia Management
Status: RECRUITING
Conditions: Stereotactic Radioablation for Ventricular Tachycardia
Interventions: RADIATION: Stereotactic Radioablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fasted Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: morphine sulfate extended-release capsules|DRUG: KADIAN (morphine sulfate extended-release) capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours
Status: RECRUITING
Conditions: Cancer|PD-L1 Gene Mutation
Interventions: BIOLOGICAL: Tumor Treatment Vaccine; PD-1/L1 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: mesenchymal stem cells (umbilical cord) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D and Arterial Stiffness in Elderly
Status: COMPLETED
Conditions: Vitamin D Deficiency|Arterial Stiffness
Interventions: DIETARY_SUPPLEMENT: Low dose vitamin D3|DIETARY_SUPPLEMENT: High dose vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Concepts in Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetes Mellitus, With Complications
Interventions: PROCEDURE: INTRAVITREAL RANIBIZUMAB INJECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-level Laser Therapy in Enhancing Wound Healing and Preserving Tissue Thickness
Status: COMPLETED
Conditions: Wounds
Interventions: DEVICE: Low-Level Laser Therapy by Ezlase; Biolase®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis
Status: UNKNOWN
Conditions: Pain|Satisfaction, Patient|Functionality
Interventions: DRUG: Dextrose|DRUG: Methylprednisolone Acetate 40 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Study Generic Fluticasone Propionate Inhalation Aerosol for the Treatment of Bronchial Asthma
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: Fluticasone propionate Inhalation Aerosol 44 mcg|DRUG: FLOVENT HFA 44 mcg|DRUG: Matching Placebo inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Ovarian Cancer Peptides Plus GM-CSF and Adjuvant With Ovarian, Tubal or Peritoneal Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian, Tubal or Peritoneal Cancer
Interventions: BIOLOGICAL: tumor peptide vaccine|BIOLOGICAL: tumor peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-dimensional Clinical and Pathophysiological Profiles of Patients With Functional Dyspepsia and Effect of Gut Microbiota Manipulation Using Rifaximin for Its Treatment
Status: UNKNOWN
Conditions: Dyspepsia
Interventions: DRUG: Rifaximin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between EDP-235, Itraconazole, Carbamazepine and Quinidine in Healthy Subjects.
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: EDP-235|DRUG: EDP-235|DRUG: EDP-235|DRUG: Itraconazole|DRUG: Carbamazepine|DRUG: Quinidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Capsaicin Gel During Exercise Within the Heat
Status: COMPLETED
Conditions: Acute Exercise|Heat Exposure
Interventions: BIOLOGICAL: Capsaicin|BIOLOGICAL: Control Gel|OTHER: Exercise|OTHER: Hot environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Foscarnet in the Treatment of HIV Infection in Patients Who Have Taken Zidovudine for a Long Time
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed as the First Treatment in Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms, Male|Carcinoma, Ductal
Interventions: DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Cardiac Output in Intensive Care Unit With Unstable Hemodynamic: Validation of Physioflow® Device Versus Trans Thoracic Echocardiography
Status: COMPLETED
Conditions: Cardiac Output
Interventions: PROCEDURE: cardiac output measure with TTE|PROCEDURE: cardiac output measure with Physioflow® thoracic electrical bioimpedance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Preprocedural Diclofenac in Males Undergoing Double J Stent Removal Under Local Anesthesia
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Diclofenac sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Aspirin and Clopidogrel Therapy (BOchum CLopidogrel and Aspirin Plan)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Optimizing ASA and clopidogrel treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARS-COV-2 Seroprevalence and Seroconversion Among Employees of the UZ Brussel Following COVID-19 Vaccination Using an Adenoviral Vector
Status: RECRUITING
Conditions: SARS-CoV-2|Covid19
Interventions: DIAGNOSTIC_TEST: Serological testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide|DRUG: 3,4-methylenedioxymethamphetamine|OTHER: LSD Placebo|OTHER: MDMA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Accelerated Partial Breast Irradiation for Triple Negative Breast Cancer Using Proton Beam Scanning
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: RADIATION: Accelerated Partial Breast Irradiation|DEVICE: AlignRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of the Nativis Voyager® System in Patients With Recurrent Glioblastoma Multiforme (GBM) in Australia
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DEVICE: Voyager
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Purified Inactivated Zika Virus Vaccine (PIZV) in Healthy Adults
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Purified Inactivated Zika Virus Vaccine (PIZV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prognosis of Right Ventricular Dysfunction Assessed by Speckle Tracking in Postoperative Thoracic Surgery
Status: RECRUITING
Conditions: Right Ventricle|Thoracic Surgery
Interventions: OTHER: transthoracic echocardiography (TTE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Association of Warfarin Dosage and Plasma Enantiomer Concentration With the Gene Polymorphisms of CYP and VKOR
Status: UNKNOWN
Conditions: Deep Venous Thromboembolism
Interventions: DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proclear 1-D Multifocal Nondispensing Study
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: omafilcon A / PC 1-D MF|DEVICE: lotrafilcon B / Air Optix MF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of PACHA Program to Enhance Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Neoplasms|Breast Cancer
Interventions: BEHAVIORAL: PACHA Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sorbact TM: Effect of a Microbial Binding Dressing on Wound Healing After Pilonidal Sinus Excision
Status: COMPLETED
Conditions: Sinus Pilonidal
Interventions: DEVICE: Algosteril TM|DEVICE: Sorbact TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance
Status: TERMINATED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Application of Transcranial Alternating Current Stimulation for Modulation of Sleep and Cognitive Performance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Relative Bioavailability and Food Effect Study of TYRA-300-B01 Capsule and Tablet Formulations in Healthy Adult Participants
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: TYRA-300-B01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The TANTALUS® II for the Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Tantalus System|DEVICE: TANTALUS system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT