pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neuropeptide Expression During the Ovarian Cycle and in Patients With PCOS
Status: RECRUITING
Conditions: PCOS
Interventions: DIAGNOSTIC_TEST: Dosage of ematic CGRP|DIAGNOSTIC_TEST: Dosage of ematic SP|DIAGNOSTIC_TEST: Dosage of ematic enkephalins|DIAGNOSTIC_TEST: Dosage of ematic VIP|DIAGNOSTIC_TEST: Dosage of CGRP in follicolar fluid|DIAGNOSTIC_TEST: Dosage of SP in follicolar fluid|DIAGNOSTIC_TEST: Dosage of enkephalins in follicolar fluid|DIAGNOSTIC_TEST: Dosage of VIP in follicolar fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dynamic Coronary Roadmap for Contrast Reduction
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Coronary Intervention (PCI) with Dynamic Coronary Roadmap|DEVICE: Percutaneous Coronary Intervention (PCI) without Dynamic Coronary Roadmap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Ianalumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Safety of a Disposable Intra-vaginal Device for Stress Urinary Incontinence
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: pessary|DEVICE: Absorbent pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mckenzie and Rhythmical Stabilization Technique on Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Mckenzie protocol|OTHER: Rhythmic Stabilization technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Plasma Genotyping For Early Initiation Of Erlotinib In EGFR Mutant Lung Cancer
Status: TERMINATED
Conditions: Epidermal Growth Factor Receptor|Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Voglibose Compared With Acarbose in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Voglibose|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Axillary Lymph Node Dissection Vs Complete Axillary Dissection: A Randomised Clinical Trial to Assess the Prevention of Lymphedema in Breast Cancer Treatment
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: SELECTIVE AXILLARY LYMPH NODE DISSECTION (SAD)|PROCEDURE: COMPLETE AXILLARY DISSECTION (ALND)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft Versus Host Disease|Hematologic Malignancies
Interventions: DRUG: Sirolimus|DRUG: Tacrolimus|DRUG: Methotrexate|PROCEDURE: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preparation and Characterization Intranasal Film Loaded With Steroid as a Local Treatment of Anosmia in Compare to Insulin Intranasal Film
Status: COMPLETED
Conditions: Smell Loss
Interventions: DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Non-opioid Post-surgical Pain Treatment in Females
Status: WITHDRAWN
Conditions: Acute Pain|Bunionectomy|Toe Fusion
Interventions: DRUG: Carbidopa-Levodopa (100mg/25mg):|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR)
Status: RECRUITING
Conditions: Bronchiectasis
Interventions: DRUG: Hypertonic saline|DRUG: Carbocysteine 750 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up Studies of Primary Snoring(PS) and Obstructive Sleep Apnea Hypopnea Syndrome(OSAHS) in Chinese Children
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: PROCEDURE: Adenotonsillectomy|OTHER: Conservative treatment|OTHER: no treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Examine the Long Term Effect of Pramlintide on Body Weight and Its Safety and Tolerability in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: pramlintide acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thyroid Disorders in Malaysia: A Nationwide Multicentre Study
Status: COMPLETED
Conditions: Hypothyroidism|Subclinical Hypothyroidism|Hyperthyroidism|Subclinical Hyperthyroidism|Graves Disease|Hashimoto's Thyroiditis|Iodine Deficiency|Genetic Susceptibility
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Study to Evaluate Double-Dose Levonorgestrel Emergency Contraception in Combination With Efavirenz-Based Antiretroviral Therapy or Rifampicin-Containing Anti-Tuberculosis Therapy
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Levonorgestrel (LNG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Prior Infection With COVID-19 on Occurrence of Influenza-like Illness or Acute Respiratory Infection
Status: COMPLETED
Conditions: Influenza, Human|SARS Virus|COVID-19|Espiratory Tract Infections
Interventions: DIAGNOSTIC_TEST: qRT-PCR and serology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: High-Intensity Focused Ultrasound Ablation in Treating Patients With Localized Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Sexual Dysfunction|Urinary Incontinence
Interventions: OTHER: questionnaire administration|PROCEDURE: biopsy|PROCEDURE: high-intensity focused ultrasound ablation|PROCEDURE: magnetic resonance imaging|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Erector Spinae Versus Serratus Anterior Plane Block for Thoracoscopic Sympathectomy
Status: UNKNOWN
Conditions: Thoracic Sympathectomy
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Empowering Hispanic Patients' Lung Cancer Screening Uptake (Empower Latinx)
Status: RECRUITING
Conditions: Lung Cancer
Interventions: OTHER: Usual Care|BEHAVIORAL: Brief Patient Education|BEHAVIORAL: Patient education|BEHAVIORAL: Referral to financial navigation resources|BEHAVIORAL: Patient Reminders|BEHAVIORAL: Provider Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: New Model of Integrated Care of Older Patients With Atrial Fibrillation in Rural China
Status: COMPLETED
Conditions: Atrial Fibrillation|Older|Stroke
Interventions: OTHER: Village doctor-led telemedicine integrated care|OTHER: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 5-Azacytidine Prior to Allogeneic Stem Cell Transplant in High Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: 5-azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ferinject® in Patient With Thrombocytosis Secondary to Inflammatory Bowel Disease (IBD)
Status: TERMINATED
Conditions: Thrombocytosis|Iron-Deficiency Anemia
Interventions: DRUG: FERINJECT® (Ferric carboxymaltose)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma
Status: RECRUITING
Conditions: Sarcoma, Ewing
Interventions: BIOLOGICAL: TK216+Vincristin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XW014 in Healthy Subjects and Patients With Type 2 Diabetes Mellitus (T2DM)
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: XW014|DRUG: Placebo|DRUG: XW014|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Status: NOT_YET_RECRUITING
Conditions: Acute Lymphoblastic Leukemia, in Relapse|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent|Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory|Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory
Interventions: DRUG: Ruxolitinib|DRUG: Venetoclax|DRUG: Dexamethasone|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: intrathecal chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safer Choices 2 - HIV, STD, & Pregnancy Prevention Program
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Diseases|Pregnancy|HIV Infections
Interventions: BEHAVIORAL: HIV, STD, Pregnancy Prevention Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Extension Study for Subjects Who Are Deriving Benefit With Idelalisib (GS-1101; CAL-101) Following Completion of a Prior Idelalisib Study
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Lymphoma, Non-Hodgkin
Interventions: DRUG: Idelalisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Rituximab (MabThera) in First Line Treatment of Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Place-based Cochlear Implant Mapping
Status: RECRUITING
Conditions: Hearing Loss, Sensorineural|Cochlear Implants
Interventions: OTHER: Place-based cochlear implant mapping|OTHER: Default cochlear implant mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study to Evaluate the Safety and PK of MP-376 in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: MP-376 (Levofloxacin solution for Inhalation)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sleep Restriction and Parental History of Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Partial sleep deprivation (sleep restriction)|BEHAVIORAL: Normal sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study Using Molecular Profiling to Find Potential Targets & Select Treatments for Pts With Met br ca
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Approved therapy will be assigned based on molecular profile and RPMA results
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Association Between the Menstrual Cycle and Weight Loss in Healthy, Overweight Premenopausal Women
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Evaluation of the Association between the Menstrual Cycle and Weight Loss in Healthy, Overweight Premenopausal Women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004
Status: TERMINATED
Conditions: Colorectal Tumors|Colorectal Neoplasms|Colorectal Carcinoma|Colorectal Adenocarcinoma|Colorectal Cancer
Interventions: DRUG: Avelumab|BIOLOGICAL: Ad-CEA vaccine|DRUG: Bevacizumab|DRUG: 5-Fluorouracil (FU)|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: 5-Fluorouracil (FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors
Status: NOT_YET_RECRUITING
Conditions: Liver Neoplasms
Interventions: DRUG: Sulfur Hexafluoride Lipid Microspheres|PROCEDURE: Contrast-Enhanced Ultrasound|PROCEDURE: Transarterial Chemoembolization|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Proprioception and Multi Sensory Training After DRF
Status: UNKNOWN
Conditions: Distal Radius Fracture|Wrist Fracture
Interventions: OTHER: Proprioceptive wrist exercises|OTHER: Wrist exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Auricular acupressure|OTHER: Placebo auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nutritional Supplementation and Dietary Advice in Elderly Patients After Hospital Discharge.
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritional supplementation with a liquid formula|OTHER: Dietary advice|OTHER: Combination of supplement and dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET/CT-directed Hyperfractionated Radiation Dose Escalation in Esophageal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: RADIATION: radiochemotherapy 1|RADIATION: radiochemotherapy 2|RADIATION: radiochemotherapy 3|RADIATION: radiochemotherapy 4|RADIATION: radiochemotherapy 5|RADIATION: radiochemotherapy 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of PAZ320 on PPG and Insulin Blood Levels in Type II Diabetic Patients
Status: WITHDRAWN
Conditions: Type II Diabetes
Interventions: DRUG: PAZ320|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spatial Repellent Products for the Control of Vector Borne Diseases - Malaria - Tanzania
Status: WITHDRAWN
Conditions: Malaria
Interventions: DEVICE: Spatial Repellent product with active ingredient|DEVICE: Active ingredient|DEVICE: Spatial Repellent product without active ingredient (SHIELD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calcium Ionophore Solution Can Increase Fertilization Rate in Patients During Intracytoplasmic Sperm Injection(ICSI) Who Have Poor Ovarian Reserve?
Status: UNKNOWN
Conditions: Fertilization Failure
Interventions: OTHER: calcium ionophore solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Prevalence Assessment and Characterization of Psychological Disorders Associated With Hypobetalipoproteinemia
Status: COMPLETED
Conditions: Hypobetalipoproteinemia
Interventions: OTHER: Hypobetalipoproteinemia diagnosis (LDL-C ≤ 50 mg/dL without hypolipidemic treatment)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1D
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Etanercept|DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remifentanil Use in Pediatric Rigid Bronchoscopy
Status: COMPLETED
Conditions: Pediatric Rigid Bronchoscopy
Interventions: DRUG: Propofol|DRUG: Ketamine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors
Status: RECRUITING
Conditions: Melanoma|Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: IO102-IO103|DRUG: Pembrolizumab KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiation Therapy Combined With Concurrent Chemotherapy for Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: RADIATION: Hypofractionated radiation/chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation for the Treatment of Asthma and Allergic Rhinitis/Rhinoconjunctivitis
Status: TERMINATED
Conditions: Allergic Rhinoconjunctivitis|Perennial Allergic Rhinitis|House Dust Mite Allergy|Pollen Allergy
Interventions: BIOLOGICAL: MM09-MG01(30.000-30.000)|BIOLOGICAL: MG01(30.000)|BIOLOGICAL: MM09(30.000)|BIOLOGICAL: Placebo subcutaneous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986326 in Participants With Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis, Atopic
Interventions: DRUG: BMS-986326|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Frontal Transcranial Direct Current Stimulation on BDNF in Stroke Patients With Cognitive Impairment
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Routine treatment|OTHER: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Vein Imaging Device Used in Peripheral Intravenous Catheter Application on the Success of the Procedure in Patients Coming to the Pediatric Emergency Department
Status: RECRUITING
Conditions: Peripheral Intravenous Catheter
Interventions: DEVICE: vein imaging device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Short-Term Appetite Suppression Trial Using Appethyl™: The Pizza
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Appethyl™|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion
Status: COMPLETED
Conditions: Inappropriate ADH Syndrome|Hyponatremia
Interventions: DRUG: SR121463B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy and Carbon Ion Radiotherapy In Solid Cancers With Stable Disease
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Melanoma|Urothelial Carcinoma
Interventions: RADIATION: Carbon Ion Therapy|DRUG: Immunotherapy (Pembrolizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Pharmacokinetics, and Safety of Presatovir in Hospitalized Adults With Respiratory Syncytial Virus (RSV) Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: DRUG: Presatovir|DRUG: Presatovir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Photobiomodulation on Functional Recovery of Proximal Humerus Fractures
Status: RECRUITING
Conditions: Bone Fracture|Humerus Fracture|Surgery
Interventions: PROCEDURE: Physiotherapy|DEVICE: Photobiomodulation|DEVICE: Simulation of photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proximal Humerus Site for Anesthesia
Status: COMPLETED
Conditions: Intraosseous Vascular Access
Interventions: PROCEDURE: proximal humerus intraosseous vascular access|DRUG: 2% preservative-free lidocaine|DEVICE: EZ-IO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Clinical Trial to Assess the Safety & Efficacy of the Treatment of Patients With Metastasis From Malignant Melanoma - Treatment Consists of the Substances Lomustine (Capsules) & Cytarabine (Injected Into an Area Near the Spinal Cord), Accompanied by Radiotherapy of the Brain
Status: TERMINATED
Conditions: Leptomeningeal Metastasis From Malignant Melanoma
Interventions: RADIATION: Brain radiotherapy (WBRT alone, SRT/SRS alone or WBRT plus SRT/SRS)|DRUG: Lomustine|DRUG: Liposomal cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)
Status: COMPLETED
Conditions: Skin Diseases, Bacterial
Interventions: DRUG: midazolam|DRUG: rosuvastatin|DRUG: tedizolid phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Efficacy and Safety of Ondansetron Oral Membrane for the Prevention of Vomiting During Moderate Hypoemetic Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: To Analyze and Compare the Efficacy and Safety of Ondansetron and Tablet for the Prevention of Moderate and Hypoemetic Chemotherapy
Interventions: DRUG: Ondansetron oral membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Denufosol Tetrasodium in Patients With Cystic Fibrosis Lung Disease
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: denufosol tetrasodium (INS37217)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate Plus LNG-IUS in Young Women With Early Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Neoplasm Malignant Stage I
Interventions: DRUG: Megestrol Acetate|DEVICE: Levonorgestrel-releasing Intrauterine System(LNG-IUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Buccal Infiltration Only Using Articaine for Extraction of Mandibular Molar
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: DRUG: Articaine 4%/Epi 1:100000 Inj Cart 1.7Ml|DRUG: Lidocaine 2%/Epi 1:100000 Inj Cart 1.7Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Atosiban in in Vitro Fertilization (IVF) Treatment
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Atosiban|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Application of an Artificial Intelligence-driven Accurate Identification Model for Gastric Cancer Lymph Node Metastasis
Status: RECRUITING
Conditions: The Primary Focus of This Study is on Gastric Cancer
Interventions: DIAGNOSTIC_TEST: AI-Driven Identification Model for Gastric Cancer Lymph Node Metastasis (AID-GLNM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Lamotrigine 2×25 mg IR Tablets of Torrent Pharmaceuticals Limited, India and Lamictal® (Lamotrigine) 2×25 mg Tablets of GlaxoSmithKline, USA, in Healthy Human Adult Subjects, Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical Follow Up of a Fissure Sealant Placed With Different Adhesive Protocols: 2-Year Randomized Split Mouth Study
Status: COMPLETED
Conditions: Fissure Sealant Loss|Caries
Interventions: OTHER: acid-etch|OTHER: self-etch adhesive|OTHER: etch-and-rinse adhesive|OTHER: self-etch adhesive after acid-etch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of a Short Early Psychological Care in Women With Miscarriage
Status: NOT_YET_RECRUITING
Conditions: Miscarriage
Interventions: OTHER: short early psychological care associated with encouragement of early support consultation with generalist practitioner or midwife|OTHER: encouragement of early support consultation with generalist practitioner or midwife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?
Status: UNKNOWN
Conditions: Acute Kidney Injury|Septic Shock
Interventions: OTHER: Nephrocheck test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Short Term Use of Experimental Eye Drops BHVI2, 0.02% Atropine and BHVI2 Plus 0.02% Atropine Eye Drops
Status: COMPLETED
Conditions: Myopia
Interventions: DRUG: Experimental BHVI2|DRUG: Atropine sulfate 0.02% eye drops|COMBINATION_PRODUCT: Combination eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Abemaciclib (LY2835219) in Participants With HR+, HER2- Advanced Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Abemaciclib|DRUG: Nonsteroidal Aromatase Inhibitor (NSAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Dose and Food Effect PK Study in Healthy Adult and Elderly Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RDN-929|DRUG: Placebo oral capsule|DRUG: RDN-929 TBD dose|DRUG: RDN-929|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome
Status: RECRUITING
Conditions: Interstitial Cystitis/Bladder Pain Syndrome
Interventions: DRUG: V117957|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease
Status: COMPLETED
Conditions: Polycystic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Niacinamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotion Study/Substudy: Flexible Brain Study
Status: COMPLETED
Conditions: Aging|Emotions|Parkinson Disease
Interventions: BEHAVIORAL: Anterior cingulate cortex activation|BEHAVIORAL: Primary auditory cortex activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Shade Match, Marginal Adaptation and Patient Satisfaction of VITA ENAMIC multiColor Versus IPS e.Max CAD Veneers
Status: UNKNOWN
Conditions: Shade Match
Interventions: PROCEDURE: anterior laminate veneers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ofatumumab Compared to Placebo in Patients With Relapsing Multiple Sclerosis Followed by Extended Treatment With Open-label Ofatumumab
Status: COMPLETED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Ofatumumab|DRUG: Matching placebo of ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aquatic Therapy for Freezing of Gait in Parkinson's Disease Patients
Status: COMPLETED
Conditions: Parkinson Disease|Gait Disorders, Neurologic|Gait Disorder, Sensorimotor
Interventions: OTHER: MIRT|OTHER: MIRT-AT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Health With Inner Engineering Meditation
Status: RECRUITING
Conditions: Meditation|Brain; Agenesis
Interventions: BEHAVIORAL: Shambhavi Madamudra Kriya
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Bothrops Spp. Snake Envenomation on Willebrand Factor Activity in Martinique and French Guiana
Status: NOT_YET_RECRUITING
Conditions: Snake Envenomation|Thrombi|Coagulopathy|Hemorrhage
Interventions: OTHER: Patients suffering from envenomation by Bothrops
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiangiogenic Therapy With Bevacizumab in Retinopathy of Prematurity. Structural Outcome
Status: RECRUITING
Conditions: Retinopathy of Prematurity
Interventions: DRUG: intravitreal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of AMG 386 and Sorafenib to Treat Advanced or Inoperable Hepatocellular Cancer
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma|Inoperable Hepatocellular Carcinoma
Interventions: DRUG: AMG 386|DRUG: AMG 386|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Discharge Sock Model in Comfort: Randomized Controlled Trial
Status: COMPLETED
Conditions: Foot Diseases|Metatarsalgia|Pain
Interventions: DIAGNOSTIC_TEST: Plantar pressures will be measured in 7 zones using the Footscan® platform following the two-step method. Three plantar pressures measurements were made for each foot.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Bio Gelee Royale Forte on Immune Health in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Upper Respiratory Tract Infection|URTI
Interventions: DIETARY_SUPPLEMENT: Bio Gelee Royale Forte|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D3 Supplementation on Cardiometabolic Risk
Status: COMPLETED
Conditions: Cardiovascular Disease|Diabetes|Bone Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
Status: RECRUITING
Conditions: Gastric Cancers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Clamping the Indwelling Urethral Catheter Before Removal From Patients After Type III Radical Hysterectomy
Status: UNKNOWN
Conditions: Gynecologic Cancer
Interventions: PROCEDURE: to clamp or release the catheter for 2 days before removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors
Status: RECRUITING
Conditions: Metastatic Cancer|Melanoma Cancer|Lung Cancer|Bladder Cancer|Renal Cancer|Head/Neck Cancers
Interventions: RADIATION: Stereotactic Body Radiotherapy|BIOLOGICAL: Ipilimumab, Nivolumab, Pembrolizumab or Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Transcranial Direct Current Stimulation (tDCS) in Patients Suffering From Pathological Use of Internet Gaming
Status: RECRUITING
Conditions: Pathological Use of Internet Games
Interventions: DEVICE: Active tDCS|DEVICE: Placebo tDCS|OTHER: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Arterial and Plethysmographic Waveforms Variables as Predictors of Hemodynamic Response to Pneumoperitoneum
Status: UNKNOWN
Conditions: Pneumoperitoneum|Heart Output Disorder
Interventions: PROCEDURE: Pneumoperitoneum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of a Cognitive and Behavioral Treatment Program in People With Idiopathic Environmental Intolerance (IEI)
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Environmental Intolerance
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid Biopsy as a Tool to Evaluate Resistance to First and Third (AZD9291) (EGFR) (TKIs) in (EGFR) Mutant NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Dose-Dependent Repeated-Dose Neramexane Effects on Cardiac Repolarisation (QT/QTc Interval Duration): Electrocardiogram (ECG) Study in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Neramexane
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Outcome of Selective & Nonselective Caries Removal in Permanent Teeth
Status: NOT_YET_RECRUITING
Conditions: Deep Caries|Carious Exposure of Pulp
Interventions: PROCEDURE: Selective Caries Removal (No Pulp Exposure)|PROCEDURE: Non-Selective Caries Removal (No Pulp exposure)|PROCEDURE: Partial Pulpotomy (Pulp Exposed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient
Status: WITHDRAWN
Conditions: IDA in the Post-bariatric Surgical Patient
Interventions: DRUG: Ferumoxytol|DRUG: Ferrous sulfate|OTHER: Oral vitamin C|OTHER: Intravenous normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Transcutaneous Electrical Acupoint Stimulation on the Quality of Oocyte on Poor Ovarian Response(POR)
Status: COMPLETED
Conditions: Poor Ovarian Response
Interventions: OTHER: TEAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker-guided Implementation of the AKI Bundle
Status: COMPLETED
Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: OTHER: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH)
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Treprostinil Palmitil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Instrumental Treatment's Predictors in Subjects With Neurological Diseases Using G-EO Robotic System
Status: RECRUITING
Conditions: Multiple Sclerosis|Stroke|Parkinson Disease|Acquired Brain Injury
Interventions: DEVICE: Robotic Assisted Gait Training with G-EO system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Meditation for Cardiometabolic Disease in Older Black Women
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease|Metabolic Syndrome
Interventions: BEHAVIORAL: Health Education|BEHAVIORAL: Transcendental Meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Sublingual Misoprostol Versus Lidocaine Spray for Hysteroscopy
Status: COMPLETED
Conditions: Pain During Hysteroscopy
Interventions: DRUG: Sublingual Misoprostol|DRUG: Lidocaine pump spray|DRUG: Placebo (for Misoprostol)|DRUG: Placebo (for Lidocaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Sensory or Motor Cues Using Electrical Stimulation to Reduce Gait Freezing in Patients With Parkinson Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DEVICE: Gait tests with and without the use of a tactile sensory cue (electrical stimulation using a TENS unit)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy
Status: RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: Ensure Enlive|OTHER: Standard Of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing
Status: NOT_YET_RECRUITING
Conditions: Drug Allergy|Cephalosporin Allergy|Drug Hypersensitivity|Antibiotic Allergy|Beta Lactam Adverse Reaction|Drug-Induced Anaphylaxis|Cephalosporin Reaction
Interventions: DRUG: Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing|DRUG: Culprit cephalosporin (cefazolin, ceftazidime, ceftriaxone, cefepime, cephalexin, cefaclor, cefadroxil, cefuroxime, cefpodoxime, cefdinir, or cefixime) double-blind placebo-controlled drug challenge|DRUG: Similar cephalosporin (cefepime, ceftriaxone, cefaclor, cephalexin, cefixime, or cefdinir) antibiotic double-blind placebo-controlled drug challenge|DRUG: Dissimilar cephalosporin (ceftriaxone or cefazolin) antibiotic double-blind placebo-controlled drug challenge|DRUG: Amoxicillin double-blind placebo-controlled drug challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenalidomide in Combination With R-DA-EPOCH in Patients With Untreated DLBCL With MYC Rearrangement
Status: RECRUITING
Conditions: DLBCL|Untreated|MYC Gene Rearrangement
Interventions: DRUG: Lenalidomide|DRUG: Rituximab|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Cyclophosphamide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Evaluate the Clinical Outcome of PrimeTaper EV Implant in Single Tooth Restorations
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: PrimeTaper EV implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Absorbable Surgical Hemostatic Agent: Thrombi-Gel® Versus Gelfoam-Thrombin
Status: COMPLETED
Conditions: Operation Site Bleed
Interventions: DEVICE: Thrombi-Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Essential Amino Acid Intake on Net Protein Synthesis in Weight-losing Non-small Cell Lung Cancer Patients
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DIETARY_SUPPLEMENT: EAA+LEU vs total AA|DIETARY_SUPPLEMENT: Total AA vs EAA+LEU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Investigating Effects of a Novel Nutraceutical on Hypercholesterolaemia in Australian Adults
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Swisse Nutra+ Cholesterol Balance|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenteric Traction Syndrome During Upper Gastrointestinal Surgery
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms|Mesenteric Traction Syndrome
Interventions: OTHER: Blood samples|OTHER: Measurement of microcirculation|OTHER: Head down tilt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Oxygen Setting During Non-invasive Mechanical Ventilation of Chronic Obstructive Pulmonary Disease
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified
Interventions: DEVICE: Non-invasive mechanical ventilation - Normoxia|DEVICE: Non-invasive mechanical ventilation - Controlled hypoxemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER