pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Osteopathic Manipulative Treatment in Pediatric Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: OTHER: OMT + Usual Care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae
Status: RECRUITING
Conditions: Lignocaine|Bupivacaine|Postpartum Perineal Pain|Vaginal Delivery|Episiotomy|Primigravidae
Interventions: DRUG: Lignocaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol)
Status: COMPLETED
Conditions: Pharmacokinetic
Interventions: DRUG: Tapentadol IR capsule|DRUG: Omeprazole capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABSORB EXTEND Clinical Investigation
Status: COMPLETED
Conditions: Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis|Cardiovascular Disease
Interventions: DEVICE: ABSORB BVS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Re-Adjustment of Sweep Gas Flow to the During the Rewarming Period of the Cardiopulmonary Bypass
Status: RECRUITING
Conditions: Optimal Sweep Gas Flow|Determination of Optimal Sweep Gas Flow for Different Phases of Cardiopulmonary Bypass
Interventions: OTHER: Gas Flow Adjustment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness and Tolerance of Inhaled Fentanyl Aerosol (25µg/Dose) in Chinese Patients With Breakthrough Cancer Pain
Status: UNKNOWN
Conditions: Breakthrough Cancer Pain
Interventions: DRUG: Inhaled fentanyl aerosol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Rotator Cuff-related Shoulder Pain and Graded Motor Imagery
Status: COMPLETED
Conditions: Chronic Pain|Shoulder Pain
Interventions: OTHER: graded motor imagery|OTHER: traditional physiotherapy method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, and Immunogenicity Study of the Recombinant Two-component COVID-19 Vaccine (CHO Cell)
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Part1:Recombinant two-component COVID-19 vaccine (CHO cell)|BIOLOGICAL: Part1: Placebo|BIOLOGICAL: Part2: Recombinant two-component COVID-19 vaccine (CHO cell)|BIOLOGICAL: Part2: COVID-19 Vaccine, mRNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Community Case Management of the Severe Pneumonia With Oral Amoxicillin in Children 2-59 Months of Age
Status: COMPLETED
Conditions: Severe Pneumonia
Interventions: DRUG: Amoxicillin|OTHER: Referral to Health facility
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19x22 Chimeric Antigen Receptor T-cell Therapy (CAR T) in Pediatric B-ALL
Status: NOT_YET_RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CD19x22 CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pattern Recognition Prosthetic Control
Status: COMPLETED
Conditions: Prosthesis User|Congenital Amputation of Upper Limb|Amputation; Traumatic, Limb
Interventions: DEVICE: EMG-Pattern Recognition Controller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|Rhinitis, Allergic, Seasonal|Asthma
Interventions: BIOLOGICAL: Clinical Center Reference Endotoxin (CCRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety of KAND567, in Combination With Carboplatin Therapy, in Women With Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: KAND567|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial Using Highly Purified Human Chorionic Gonadotropin (HP-hCG) and Recombinant Human Chorionic Gonadotropin (rhCG) in Women Undergoing Controlled Ovarian Stimulation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: highly purified human chorionic gonadotropin|DRUG: recombinant human chorionic gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol and Immune Response
Status: COMPLETED
Conditions: Alcohol Drinking|Alcohol; Harmful Use
Interventions: DRUG: Alcohol, Ethyl|OTHER: Alcohol, Ethyl - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single Agent Ofatumumab Vs. Single Agent Rituximab in Indolent B-Cell Non Hodgkin Lymphoma Relapsed After Rituximab-Containing Therapy
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma
Interventions: BIOLOGICAL: Ofatumumab|BIOLOGICAL: Rituximab|BIOLOGICAL: Ofatumumab|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NRTI-Sparing Pilot Study
Status: COMPLETED
Conditions: HIV|Mitochondrial Toxicity
Interventions: DRUG: lopinavir/ritonavir; nevirapine; Zidovudine; Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Laryngoscopic View by Bed-up-head-elevated Position During Tracheal Intubation in Paediatric Patients
Status: RECRUITING
Conditions: Paediatric Airway Management
Interventions: PROCEDURE: Intubation in Bed-Up-Head-Elevated (BUHE) position
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Study of Iliac Bifurcation Stent Graft System
Status: UNKNOWN
Conditions: Aortoiliac Aneurysm|Iliac Aneurysm
Interventions: DEVICE: Iliac Bifurcation Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-fatigue Effect of Korean Red Ginseng in Patients With Non-alcoholic Hepatitis
Status: COMPLETED
Conditions: Fatigue
Interventions: DRUG: KRG (Korea Red ginseng)|DRUG: Placebo (for KRG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reflex Responses to Intermittent Hypoxia in Humans: Mechanisms and Consequences
Status: COMPLETED
Conditions: Sleep Apnea|Healthy|Vasoconstriction|Vasodilation
Interventions: OTHER: Hypoxic exposure|OTHER: modified Oxford test|DRUG: Oral Bosentan 62.5 mg|OTHER: Hypoxic ventilatory response test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Safety and Immunogenicity of the Influenza Vaccine GSK2186877A in the Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine GSK2186877A|BIOLOGICAL: GSK Biologicals' Fluarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Cancer of the Pancreas Screening-5 CAPS5)Study
Status: RECRUITING
Conditions: Pancreas Cancer|Peutz-Jeghers Syndrome (PJS)|Gene Mutation|Germline Mutation Carrier|Lynch Syndrome
Interventions: DRUG: Secretin|DIAGNOSTIC_TEST: MRI|OTHER: Tumor marker gene test with CA19-9
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alcohol Consumption, Intention Implementation and Mindfulness Meditation (ADUC-Volet 3 " Prevention ")
Status: RECRUITING
Conditions: Binge Drinking|Alcohol Drinking
Interventions: BEHAVIORAL: MBM and II|BEHAVIORAL: MI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)
Status: COMPLETED
Conditions: Hypercholesterolemia|Atherosclerosis|Coronary Artery Disease
Interventions: DRUG: Ezetimibe + Atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
Status: RECRUITING
Conditions: Hernia, Ventral|Intestinal Fistula|Fibromatosis, Abdominal
Interventions: PROCEDURE: Abdominal wall reconstruction with Strattice|OTHER: Assess pain intensity at last office visit preoperatively|OTHER: Assess pain interference at last office visit preoperatively|OTHER: Assess physical functioning at last office visit preoperatively|OTHER: Assess patient quality of life at last office visit preoperatively|OTHER: Assess patient pain intensity postoperatively|OTHER: Assess pain interference postoperatively|OTHER: Assess physical functioning postoperatively|OTHER: Assess quality of life postoperatively|OTHER: Assess hernia recurrence at 30 days postoperatively|OTHER: Assess bulge at 30 days postoperatively|OTHER: Assess Surgical Site Occurrences at 30 days postoperatively|OTHER: Assess hernia recurrence at 1 year postoperatively|OTHER: Assess bulge at 1 year postoperatively|OTHER: Assess Surgical Site Occurrences at 1 year postoperatively|OTHER: Assess overall complications at 30 days postoperatively|OTHER: Assess overall complications at 1 year postoperatively|PROCEDURE: Abdominal wall reconstruction with XenMatrix|DEVICE: Strattice|DEVICE: XenMatrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Skeletal Muscle Dysfunction in Patient With Idiopathic Pulmonary Fibrosis
Status: UNKNOWN
Conditions: Interstitial Lung Disease|Skeletal Muscle Dysfunction
Interventions: DIAGNOSTIC_TEST: Six-minute walking test|DIAGNOSTIC_TEST: 30 seconds chair stand test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Hyperglycemia|Hyperglucagonemia|Glucose Intolerance
Interventions: OTHER: GLP-1 infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Sutra Hemi-valve First-in-Human Study
Status: NOT_YET_RECRUITING
Conditions: Mitral Regurgitation
Interventions: DEVICE: Sutra Hemi-valve Transcatheter Mitral Valve Replacement (TMVR) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair
Status: RECRUITING
Conditions: Postoperative Constipation|Pelvic Organ Prolapse Vaginal Surgery|Defecation Function
Interventions: DEVICE: Defecation Posture Modification Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Miricorilant in Patients With Presumed Nonalcoholic Steatohepatitis (NASH)
Status: COMPLETED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: Miricorilant 150 mg|DRUG: Miricorilant 100 mg|DRUG: Miricorilant 50 mg|DRUG: Miricorilant 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effect and Safety of Tamsulosin 0.4mg in Patients With LUTS/BPH Refractory to Tamsulosin 0.2mg
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: tamsulosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mesenchymal Stem Cells in Newly-diagnosed Type 1 Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: BIOLOGICAL: Intravenous Mesenchymal stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Will be an Open-label, Three-period, Fixed-sequence Study to Evaluate the Drug-drug Interaction, Pharmacokinetics and Safety of Dutasteride and Tamsulosin When Administered Alone and In-combination in Chinese Healthy Male Volunteers. The Study Will Last Approximately Eleven Weeks. Blood Samples
Status: COMPLETED
Conditions: Prostatic Hyperplasia
Interventions: DRUG: Dutasteride and Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Safety Study for the Treatment of Presbyopia Subjects
Status: COMPLETED
Conditions: Presbyopia|Near Vision|Miosis|Eye Diseases
Interventions: DRUG: Aceclidine+Brimonidine combination ophthalmic solution|DRUG: Placebo|DRUG: Aceclidine Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Switching From Donepezil to Rivastigmine Patch in Patients With Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine 5 cm^2 transdermal patch|DRUG: Rivastigmine 10 cm^2 transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meat And Dietary Pattern Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: High Healthy Eating Index Diet with Minimally Processed Meat|OTHER: High Healthy Eating Index Diet with Further Processed Meat|OTHER: Typical Healthy Eating Index Diet with Minimally Processed Meat|OTHER: Typical Healthy Eating Index Diet with Further Processed Meat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of UTTR1147A in Participants With Neuropathic Non-Healing Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Neuropathic Diabetic Foot Ulcers
Interventions: DRUG: Placebo|DRUG: UTTR1147A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Allergen Inhalation on Sputum Myeloid and Plasmacytoid Dendritic Cells in Mild Atopic Asthmatics
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Aeroallergen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Opioid-Free Anesthesia in Cardiac Surgery
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Dexmédétomidine 0.5 g/kg + lidocaine 1.5 mg/kg|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)
Status: COMPLETED
Conditions: Atrial Fibrillation|Tachycardia, Supraventricular|Arrhythmia|Bradycardia
Interventions: DEVICE: Intervention Pacing Features
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Polymorphisms in Key Genes of Glycolytic Pathway: Influence on Radiosensitivity in Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma|Single Nucleotide Polymorphisms|Radiosensitivity
Interventions: OTHER: validation group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Relative Bioavailability of Orally Administered JNJ-42756493 Tablet Versus JNJ-42756493 Capsule in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42756493 Tablet|DRUG: JNJ-42756493 Capsule|DRUG: JNJ-61818549
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications
Status: NOT_YET_RECRUITING
Conditions: Social Anxiety
Interventions: OTHER: JOURNeY anonymous|OTHER: JOURNeY standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer
Status: COMPLETED
Conditions: Suspected Primary Prostate Cancer
Interventions: DEVICE: ProxiScan (scintigraphic rectal probe)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: SPD489 low dose range (40mg, 80mg, and 100mg)|DRUG: SPD489 high dose range (120mg, 140mg and 160mg)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Melatonin in the Regulation of Blood Coagulation
Status: COMPLETED
Conditions: Spinal Cord Injured, Tetraplegia
Interventions: DRUG: Melatonin ("Circadin")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Using a Mobile Application for Type 2 Diabetes Self-care
Status: UNKNOWN
Conditions: Type 2 Diabetes|Diabetes Mellitus, Type 2|Disease, Chronic|Self-Care|Health Behavior|Mobile Apps|Mobile Phone Use
Interventions: OTHER: Mobile app forDiabetes (Tessera Multimedia, 2020)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
Status: NOT_YET_RECRUITING
Conditions: ACL Tear
Interventions: PROCEDURE: ACL reconstruction with BTB autograft with internal brace augmentation (suture tape)|PROCEDURE: ACL reconstruction with BTB autograft without internal brace augmentation (suture tape)|OTHER: Standardized Rehabilitation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Different Mood States and Emotions on the Physiologic, Metabolic, and Perceptual Responses to Feeding Before Exercise
Status: RECRUITING
Conditions: Other Gastrointestinal Disorders|Cramp, Abdominal
Interventions: OTHER: Funny/Amusing Video Clips|OTHER: Horror/Scary Video Clips|OTHER: Thrilling/Suspenseful Video Clips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Advantage of Using Intraoperative Visual Evoked Potentials to Preserve Visual Function During Surgical Procedures Near the Optical Pathways
Status: COMPLETED
Conditions: Surgery|Optic Nerve and Pathway Injury
Interventions: DEVICE: Visual evoked potentials monitoring during neurosurgery - Vision monitor MonOpera®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Effects of Lidocaine Infusion on Quality of Recovery and Agitation After Functional Endoscopic Sinus Surgery
Status: UNKNOWN
Conditions: Chronic Polypous Rhinosinusitis
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Opioids on Central Control of Ventilation in Children With Obstructive Sleep Apnea
Status: RECRUITING
Conditions: OSA|Opioid|Adenotonsillectomy
Interventions: DRUG: Fentanyl Citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Ranibizumab in Japanese Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration
Status: COMPLETED
Conditions: Subfoveal Choroidal Neovascularization(CNV) Secondary to Age-related Macular Degeneration (AMD)
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of XFBD, a TCM, in Persons With COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Xuanfei Baidu Granules|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact on Quality of Life of Osteopathic Visceral Mobilizations After Endometriosis Surgery
Status: NOT_YET_RECRUITING
Conditions: Endometriosis|Osteopathy in Diseases Classified Elsewhere
Interventions: OTHER: osteopatic visceral mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Diagnostic Accuracy Between US-guided Percutaneous Lung Biopsies vs CT-guided in Peripheral Lung Lesions
Status: RECRUITING
Conditions: Peripheral Lung Lesions
Interventions: DIAGNOSTIC_TEST: US-GUIDED PERCUTANEOUS LUNG NEEDLE BIOPSY|DIAGNOSTIC_TEST: CT-GUIDED PERCUTANEOUS LUNG NEEDLE BIOPSY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk Stratification-directed Therapy for AML With t(8;21) /AML1-ETO+
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Risk Stratification
Interventions: OTHER: Consolidation with chemotherapy (CT) or autologous hematopoietic stem cell transplantation (auto-HSCT)|OTHER: Consolidation with auto-HSCT or HLA-matched HSCT|OTHER: allogeneic HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Safety And Performance of The Freedom Total Knee® System With The PEEK-OPTIMA Femoral Component
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Rheumatoid Arthritis of Knee|Traumatic Arthritis of Knee (Diagnosis)|Polyarthritis|Fractures, Bone
Interventions: DEVICE: PEEK-Optima Femoral Component
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Endovascular Treatment or Standard Medical Care for Cerebral Venous Sinus Thrombosis(ESCORT)
Status: RECRUITING
Conditions: Cerebral Venous Sinus Thrombosis
Interventions: DRUG: Heparin|PROCEDURE: Endovascular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor Kinase Inhibitor Concentrations Measured by PET
Status: COMPLETED
Conditions: Disseminated Malignant Neoplasm
Interventions: OTHER: [11C] kinase inhibitor PET [15O]water PET and tumor biopsies.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Third Trimester Modified Biophysical Profile Scan for Predicting Fetal Outcome.
Status: COMPLETED
Conditions: Perinatal Death|Third Trimester Modified Biophysical Profile Scan
Interventions: OTHER: Modified Biophysical Profile scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: In Vivo Study to Assess the Recovery and Survival of Radiolabeled Autologous INTERCEPT Apheresis Platelet Components Suspended in 100% Plasma Stored for up to 7 Days
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: INTERCEPT Treated Platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metformin Glycinate in Patients With MS or DM2 , Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2
Status: WITHDRAWN
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2|Metabolic Syndrome|Type 2 Diabetes
Interventions: DRUG: metformin glycinate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on Diabetic Foot Using Peripheral Blood Derived Stem Cells for Treating Critical Limb Ischemia
Status: UNKNOWN
Conditions: Diabetic Foot|Critical Limb Ischemia|Leg Ulcers
Interventions: PROCEDURE: will receive G-CSF and peripheral blood derived mononuclear cells|DRUG: G-CSF|DRUG: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Test of the Effectiveness of a Device and Distraction for Pediatric Immunization Pain
Status: COMPLETED
Conditions: Procedural Pain
Interventions: DEVICE: Device: Buzzy|DEVICE: Buzzy: sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma|Brain Tumor
Interventions: DRUG: Bevacizumab|BEHAVIORAL: Modified Atkins Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence for Digital Cholangioscopy Neoplasia Diagnosis
Status: COMPLETED
Conditions: Common Bile Duct Neoplasms|Non-Neoplastic Bile Duct Disorder
Interventions: DIAGNOSTIC_TEST: AI model classification|DIAGNOSTIC_TEST: DSOC endoscopist experts' classification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Oxymetazoline 1% Cream to RHOFADE
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Oxymetazoline hydrochloride Cream, 1%|DRUG: Rhofade™ (oxymetazoline) cream, 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer|PDAC - Pancreatic Ductal Adenocarcinoma|Pancreas Cancer|Pancreatic Neoplasms
Interventions: DRUG: surufatinib + camrelizumab + nab-paclitaxel + S-1|DRUG: nab-paclitaxel + gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian Cancer
Status: COMPLETED
Conditions: Neoplasms|Triple Negative Breast Cancer|Ovarian Cancer|Breast Cancer|Metastatic Breast Cancer|Advanced Breast Cancer|Stage IV Breast Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: niraparib|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis ,
Status: COMPLETED
Conditions: Non-infectious Intermediate Uveitis|Non-infectious Posterior Uveitis|Non-infectious Panuveitis
Interventions: DRUG: LFG316|DRUG: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lebrikizumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Lebrikizumab|DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Physical Activity Performance and Dynamic Hyperinflation in Patients With Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis Adult
Interventions: DIAGNOSTIC_TEST: cardiopulmonary exercise testing with dynamic hyperinflation maneuver|DIAGNOSTIC_TEST: spirometry|DIAGNOSTIC_TEST: pletysmography|DIAGNOSTIC_TEST: forced oscillometry technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Popliteal Aneurysms With VIABAHN Stent Graft in Elective Surgery
Status: UNKNOWN
Conditions: Popliteal Aneurysm
Interventions: DEVICE: Endovascular treatment of aneurysms of the popliteal artery by GORE VIABAHN® stent in elective surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Risk Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Tumors|Primary Neoplasm|Secondary Neoplasm|Surgery
Interventions: OTHER: Preoperative risk stratification|OTHER: Postoperative risk stratification|OTHER: Risk-based, escalating levels of care|OTHER: Risk-based, escalating levels of monitoring|OTHER: Risk-based, escalating levels of co-management|OTHER: Standard postoperative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 1% Atropine "5+3" Regimen in Children and Adolescents Controlling Myopia
Status: RECRUITING
Conditions: Myopia
Interventions: DRUG: 1% atropine 5+3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy in Treatment of Female Pattern Hair Loss Using 5% Minoxidil Solution Combinded With Zinc Supplement
Status: UNKNOWN
Conditions: Female Pattern Alopecia
Interventions: DRUG: 15 mg Chelate zinc supplement|DRUG: Placebo drug supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing Safety and Therapeutic Activity of AFFITOPE® PD01A and PD03A in Patients With Early MSA
Status: COMPLETED
Conditions: Multiple System Atrophy|Neurodegenerative Diseases
Interventions: BIOLOGICAL: AFFITOPE® PD01A + Adjuvant|BIOLOGICAL: AFFITOPE® PD03A + Adjuvant|BIOLOGICAL: Adjuvant without active component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of OSI-461 in Patients With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: OSI-461
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of Multi-herb Formulae and an Ashwagandha Root Formula on the Modulation of the Stress and Related Symptoms
Status: COMPLETED
Conditions: Stress
Interventions: OTHER: VL-G-A57|OTHER: VL-G-E12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Compare Various Dosing and Titration Guidelines of Insulin Delivered Via V-Go ® in Patients With Type 2 Diabetes Initiating Basal Bolus Therapy in Primary Care Offices
Status: UNKNOWN
Conditions: Diabetes Type II
Interventions: DEVICE: V-Go
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of FODMAP Content in Tube Feeding Formula on Feeding Intolerance and Nutritional Status Improvement
Status: COMPLETED
Conditions: Enteral Nutrition
Interventions: DIETARY_SUPPLEMENT: low FODMAP|DIETARY_SUPPLEMENT: moderate FODMAP|DIETARY_SUPPLEMENT: high FODMAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study to Assess Efficacy and Safety of a New Compression System in the Management of Venous Leg Ulcers
Status: TERMINATED
Conditions: Venous Leg Ulcer
Interventions: DEVICE: Kit Biflex|DEVICE: Profore
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quadratus Lumborum Block Types
Status: RECRUITING
Conditions: Pain|Opioid Use|Lumbar Disc Herniation
Interventions: DRUG: Ropivacaine injection Location 1|DRUG: Ropivacaine injection Location 2|DRUG: Multimodal Pharmacological Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Safety and Tolerability of INCSHR01210 in Cancer Patients
Status: COMPLETED
Conditions: Solid Tumors and Hematologic Malignancy
Interventions: BIOLOGICAL: INCSHR01210 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Normal Prostate: Oxygenation of the Prostate Gland in Men Undergoing Prostate Biopsy
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: Oxygen measurement - Eppendorf machine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: New E-Service for a Dietary Approach to the Elderly
Status: COMPLETED
Conditions: Aged|Healthy
Interventions: BEHAVIORAL: Optimal Diet|DIETARY_SUPPLEMENT: VSL#3®|DIETARY_SUPPLEMENT: AISA-5203-L|DIETARY_SUPPLEMENT: Argan oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood
Status: NOT_YET_RECRUITING
Conditions: Sleep Problem|Neurobehavioral Manifestations
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: SCRI-huCAR19v1|BIOLOGICAL: SCRI-huCAR19v2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin Impact on Hepatic Decompensation
Status: COMPLETED
Conditions: Quality of Life
Interventions: DRUG: Atorvastatin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Listening to Lullabies and Self-selected Music on Prenatal Stress and Anxiety in Pregnant Women
Status: COMPLETED
Conditions: Anxiety, Stress-Related, in Pregnancy
Interventions: OTHER: listening to lullabies or self-selected music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Touchscreen-based Cognitive Tests in Healthy Volunteers
Status: UNKNOWN
Conditions: Cognitive Symptom|Schizophrenia
Interventions: DRUG: Ketamine 0.58|DRUG: Ketamine 0.31|DRUG: Modafinil|DRUG: Placebo for ketamine|DRUG: Placebo for modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of PENNVAX-B Vaccine Alone, With Il-12, or IL-15 in Healthy Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: PennVax B|BIOLOGICAL: IL-12|BIOLOGICAL: IL-15
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: zelquistinel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Condom Use Attitudes, Beliefs, and Behaviors
Status: COMPLETED
Conditions: Condom Use
Interventions: BEHAVIORAL: Attitudes Only|BEHAVIORAL: Norms Only|BEHAVIORAL: Perceived Behavioral Control Only|BEHAVIORAL: Intentions Only|BEHAVIORAL: Three Constructs|BEHAVIORAL: Four Constructs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of Gadoteric Acid in Non-Coronary Magnetic Resonance (MR) Angiography
Status: COMPLETED
Conditions: Arterial Occlusive Disease
Interventions: DRUG: gadoteric acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: EG-VEGF : Potential Marker of Pre-eclampsia and / or Intrauterine Growth Restriction
Status: COMPLETED
Conditions: Pre-eclampsia|Intra-uterine Growth Retardation
Interventions: OTHER: blood sample and doppler Ultrasound of uterine arteries
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multicenter, Open-label Randomized Crossover Trial to Assess Subject Preference for Kemstro™ Compared to Conventional Baclofen Tablets in Subjects With Stable Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Kemstro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Phenytoin Phonophoresis on Pressure Ulcer Healing
Status: COMPLETED
Conditions: Pressure Ulcer
Interventions: OTHER: Phenytoin phonophoresis|OTHER: Sham phenytoin phonophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neuroimaging, Omega-3 and Reward in Adults With ADHD (NORAA) Trial
Status: TERMINATED
Conditions: Attention Deficit Disorder|Attention Deficit Hyerpactivity Disorder
Interventions: OTHER: Highly unsaturated omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Immunogenicity and Safety of an Ebola Virus (EBOV) Glycoprotein (GP) Vaccine in Healthy Subjects
Status: COMPLETED
Conditions: Ebola
Interventions: BIOLOGICAL: Base Dose EBOV GP Vaccine|BIOLOGICAL: 2x Base Dose EBOV GP Vaccine|BIOLOGICAL: 4x Base Dose EBOV GP Vaccine|BIOLOGICAL: 8x Base Dose EBOV GP Vaccine|BIOLOGICAL: Placebo|BIOLOGICAL: Matrix-M Adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Stress Reduction in Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian, Fallopian, and Primary Peritoneal Cancer
Interventions: BEHAVIORAL: Daily stress reduction program|OTHER: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of a Hedgehog Pathway Inhibitor (LDE-225) in Surgically Resectable Pancreas Cancer
Status: WITHDRAWN
Conditions: Resectable Pancreatic Cancer
Interventions: DRUG: LDE-225
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet Among Persons With Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Skin and Connective Tissue Diseases
Interventions: DRUG: Canoderm|DRUG: Oviderm|DRUG: Decubal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Teriflunomide as Adjunctive Therapy to Interferon-beta in Subjects With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Teriflunomide|DRUG: Placebo (for Teriflunomide)|DRUG: Interferon-β
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine
Status: COMPLETED
Conditions: Niemann-Pick Disease, Type C
Interventions: DRUG: N-Acetyl Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TUSC2-nanoparticles and Erlotinib in Stage IV Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: DOTAP:Chol-TUSC2|DRUG: Erlotinib|DRUG: Dexamethasone|DRUG: Diphenhydramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MT-R Followed by Autologous Stem Cells Transplantation in Newly-diagnosed Primary Central Nervous System Lymphoma
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: R-MT followed by auto-HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing 13-valent Pneumococcal Conjugate Vaccine in Healthy Chinese Infants and Young Children
Status: COMPLETED
Conditions: Pneumococcal Infections|Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13vPnC|BIOLOGICAL: Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intrathecal Baclofen Therapy and Paroxysmal Dysautonomia in Severe Brain-Injured Patients
Status: TERMINATED
Conditions: Traumatic Brain Injury|Cerebral Anoxia|Coma|Hypertonia|Dysautonomia
Interventions: DRUG: baclofen (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Financial Health Educational Program for Increasing Financial Literacy Among Underserved Communities in Western New York
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention|OTHER: Educational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Intranasal Corticosteroid and Montelukast On Nasal Allergen Challenges*
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Fluticasone|DRUG: Fluticason
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Elicitation of Steady-state Audiovisual Responses in 6- and 10-month-old Infants
Status: NOT_YET_RECRUITING
Conditions: Speech
Interventions: BEHAVIORAL: Magnetoencephalography (MEG)|OTHER: Cognition development questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER