pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Sacral Nerve Modulation on Urinary and Defecation Dysfunction After Spinal Cord Injury：A Prospective, Single-arm Study
Status: RECRUITING
Conditions: Cystometry|Sacral Neuromodulation|Ultrasound
Interventions: DEVICE: sacral neuromodulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of HoLEP and TURP on LUTS Secondary to BPH
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Transurethral resection of the prostate|PROCEDURE: Holmium Laser Enucleation of the Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients
Status: RECRUITING
Conditions: Delirium|Aged|Lung Neoplasms|Robotic Surgical Procedures|Thoracic Surgery, Video-Assisted
Interventions: DRUG: Acetaminophen and Ibuprofen|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study of Two Ibuprofen Arginine Granules 400 mg Formulations Under Fasting and Fed Conditions in Chinese Healthy Adult Subjects
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen arginine granules 400 mg|DRUG: Ibuprofen arginine granules 400 mg (Spedifen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Niacin and Endothelial Function in Early CKD
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Niacin|DRUG: Active Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of DA-5204 on Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Esophageal Disease
Interventions: DRUG: Pantoprazole|DRUG: DA-5204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation for Male Subfertility
Status: NOT_YET_RECRUITING
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: Active multi-ingredient supplement (Fertility Enhancer, FE)|DIETARY_SUPPLEMENT: Inactive placebo (Placebo; PLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of H.P. ACTHAR GEL in Adults With Retinal Vasculitis
Status: UNKNOWN
Conditions: Uveitis, Posterior|Vasculitis Retinal
Interventions: DRUG: H.P. ACTHAR GEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: RAD001, Docetaxel, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lidocaine Versus Magnesium on Postoperative Pain in Spine Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Lidocaine IV|DRUG: Magnesium Sulfate Injection|DRUG: IV saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma, Non-Hodgkin|Diffuse Large B Cell Lymphoma
Interventions: BIOLOGICAL: CD19-targeted Chimeric Antigen Receptor(CAR) T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PhII Trial Panitumumab, Nivolumab, Ipilimumab in Kras/Nras/BRAF Wild-type MSS Refractory mCRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: Panitumumab|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Neoadjuvant Paclitaxel Plus Carboplatin/Epirubicin Treatment in Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Paclitaxel plus carboplatin|DRUG: Paclitaxel and epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirvaso® Gel and Dysport® for Erythema and Flushing of Rosacea
Status: TERMINATED
Conditions: Erythema and Flushing Associated With Rosacea
Interventions: DRUG: Mirvaso® (brimonidine) topical gel, 0.33%|DRUG: Dysport®|DRUG: Dysport® in conjunction with Mirvaso (brimonidine) topical gel, 0.33%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Different Dosing Regimens of Morphine in Patients With Moderate to Severe Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Morphine 0.1mg/kg versus morphine 0.15 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Developmental Psychopathology and the Gene-environment Interaction
Status: COMPLETED
Conditions: Developmental Psychological Disorder
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Clinical and Neuropsychological evaluations|DIAGNOSTIC_TEST: Drawing DNA sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Foster® 100/6 µg/unit dose|DRUG: Seretide Accuhaler® 500/50 µg/actuation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Xoft® Axxent® eBx® IORT System®
Status: ACTIVE_NOT_RECRUITING
Conditions: Invasive Ductal Carcinoma|Ductal Carcinoma in Situ
Interventions: RADIATION: Intra-operative Radiation Therapy - IORT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-dose Prednisone in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety Study of Recombinant Human Erythropoietin -Alpha, in Patients With Anemia of Chronic Renal Failure
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Recombinant Human Erythropoietin alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acupuncture in Patients With Lower Extremity Amputation With Neuroma
Status: COMPLETED
Conditions: Neuroma Amputation
Interventions: OTHER: Only TENS|PROCEDURE: Acupuncture+TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy
Status: COMPLETED
Conditions: Corneal Edema
Interventions: DRUG: Netarsudil Ophthalmic|DRUG: Netarsudil Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for Pain Treatment in Gulf War Illness.
Status: TERMINATED
Conditions: Gulf War Syndrome
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Characterize the Durability of Hypertonic Saline to Enhance Mucociliary Clearance in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DEVICE: Hypertonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4"S" - Seasonal Symptoms Suppression Study
Status: UNKNOWN
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Xylometazoline - intranasal application|DRUG: Azelastine - intranasal application|DRUG: Mometasone furoate - intranasal application|DRUG: Hydroxyl-propyl-methyl cellulose powder - intranasal application|OTHER: Placebo - Lactose powder|DRUG: Bilastine 20 mg|DRUG: Prednisolone 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Patient Reported Outcomes in Korean Renal Transplant Patients With and Without Gastrointestinal (GI) Symptoms
Status: COMPLETED
Conditions: Renal Transplant
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)
Status: COMPLETED
Conditions: Aspergillosis
Interventions: DRUG: MK0991, caspofungin acetate|DRUG: Comparator: amphotericin B|DRUG: Comparator: lipid formulation of amphotericin B and/or azole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differential DNA Methylation as a Function of a Parenting Intervention
Status: COMPLETED
Conditions: Maltreatment, Child
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-Up|BEHAVIORAL: Developmental Education for Families
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Care System Application Effectiveness Study on the Treatment of Diabetic Patients in Bandung
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Medwell Preventive Care Application|DEVICE: Manual Records
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of Bronchodilation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD
Interventions: DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Glulisine in Diabetes Mellitus, Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glulisine|DRUG: Insulin Therapy|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efavirenz and Lamivudine/Zidovudine for Treatment-Naive HIV Infected Adults in Senegal
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz|DRUG: Lamivudine/zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tai Chi Easy in Treating Cancer Survivors With Peripheral Sensory Neuropathy
Status: WITHDRAWN
Conditions: Cancer Survivor|Peripheral Sensory Neuropathy
Interventions: OTHER: Educational Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry
Status: COMPLETED
Conditions: Opioid Prescribing|Pain Management
Interventions: BEHAVIORAL: Academic detailing (AD)|OTHER: Continuing educational
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Throid Dysfunction in Liver Failure and Its Eddects Upon Outcome
Status: RECRUITING
Conditions: Hepatic Encephalopathy|Hepatic Impairment|Hypothyroidism|Hepatic Failure
Interventions: DIAGNOSTIC_TEST: hypothroidism|DIAGNOSTIC_TEST: euothyroid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1 Study of TDM-180935 Following Topical Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TDM-180935|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Disability in Anemic Elderly Patients With Kidney Disease Receiving PROCRIT (Epoetin Alfa)
Status: TERMINATED
Conditions: Anemia|Kidney Diseases
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate GR1801's Efficacy and Safety
Status: RECRUITING
Conditions: Rabies Post-exposure Prophylaxis
Interventions: BIOLOGICAL: GR1801|BIOLOGICAL: Human Rabies Immunoglobulin(HRIG)|BIOLOGICAL: Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Aliskiren/Amlodipine and Amlodipine on Ankle Foot Volume (AFV) in Patients With Hypertension
Status: TERMINATED
Conditions: Hypertension|Ankle Edema
Interventions: DRUG: Aliskiren/amlodipine|DRUG: Amlodipine|DRUG: Placebo to Aliskiren/amlodipine|DRUG: Placebo to Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Cilostazol in Patients With Mild Cognitive Impairment (COMCID)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
Status: COMPLETED
Conditions: Ascites|Blunt Abdominal Trauma|Cholelithiasis|Cholecystitis|Cholangitis|Pancreatitis|Hydronephrosis|Abdominal Aortic Aneurysm|Hepatitis|Portal Hypertension|Urolithiasis|Abnormal Uterine Bleeding|Ovarian Mass|Ovarian Torsion
Interventions: DEVICE: SonoSite Titan portable ultrasound coupled with email telediagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development of a mHealth Intervention for Ambivalent Smokers
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking Cessation|Motivation|Behavior, Smoking
Interventions: DEVICE: Control mHealth program|DEVICE: Experimental mHealth program|DRUG: Nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Evaluation of Atezolizumab-Venetoclax-Obinutuzumab Combination in Relapse/Refractory Lymphomas
Status: COMPLETED
Conditions: Follicular Lymphoma|Diffuse Large B Cell Lymphoma|Marginal Zone Lymphoma|Mucosa Associated Lymphoid Tissue
Interventions: DRUG: Atezolizumab|DRUG: Obinutuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact Of Eplerenone On Cardiovascular Outcomes In Patients Post Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Eplerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts
Status: UNKNOWN
Conditions: Warts
Interventions: DRUG: Candida Antigen|DRUG: Zinc Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion Therapy of Fruquintinib in Combination With Sintilimab and SOX in Unresectable Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: fruquintinib + sintilimab + SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Study of Vaginal AZU-101 in Postmenopausal Women
Status: NOT_YET_RECRUITING
Conditions: Postmenopausal Symptoms
Interventions: DRUG: Lasofoxifene Tartrate (AZU-101)|DRUG: Lasofoxifene Tartrate (AZU-101)|DRUG: Lasofoxifene Tartrate (AZU-101)|DRUG: Lasofoxifene Tartrate (AZU-101)|DRUG: Lasofoxifene Tartrate (AZU-101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of the Salmeterol Component of Fluticasone /Salmeterol Spiromax Compared to Fluticasone Spiromax and Advair Diskus in Asthma Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fp MDPI|DRUG: FS MDPI|DRUG: Advair Diskus|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electronic Clinical Decision Support for Diabetes and Dysglycaemia in Secondary Mental Healthcare
Status: COMPLETED
Conditions: Severe Mental Disorder|Diabetes Mellitus|Dysglycemia|Staff Attitude
Interventions: OTHER: Access to eCDSS on wards
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval Randomized Control Trial (RCT)
Status: COMPLETED
Conditions: Coronary Occlusion|Thrombosis (Stent Thrombosis)|Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: XIENCE V EECSS|DEVICE: CYPHER SELECT PLUS SECSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trail to Compare Pharmacokinetics of Two PEG-rhGH Injections With Different Preparations
Status: NOT_YET_RECRUITING
Conditions: Pediatric Growth Hormone Deficiency (PGHD)
Interventions: DRUG: PEG-rhGH with new preparation|DRUG: PEG-rhGH with present preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer
Status: UNKNOWN
Conditions: Glioblastoma Multiforme|Glioblastoma|GBM|Grade IV Astrocytoma|Glioma|Brain Cancer|Brain Tumor
Interventions: DRUG: Dendritic cell immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IRIS : Use of Implantable Defibrillator in High-risk Patients Early After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Implantable cardioverter defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Soft Tissue Changes Around Dental Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Tooth Loss|Dental Diseases|Wound Heal
Interventions: PROCEDURE: Soft tissue augmentation surgery with CTG|PROCEDURE: Soft tissue augmentation surgery with Fibro-Gide|PROCEDURE: No soft tissue augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Acupoint Application Combined With Ear Acupoint Embedding in Patients After Esophageal Cancer Surgery
Status: UNKNOWN
Conditions: Traditional Chinese Medicine
Interventions: BEHAVIORAL: traditional nursing method|BEHAVIORAL: Precise acupoint application combined with ear acupoint embedding nursing program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma
Status: RECRUITING
Conditions: Pediatric Obesity|Pediatric Asthma
Interventions: DEVICE: Pro2 - 60% of participant's MIP|DEVICE: Pro2 - 15% of participant's MIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Father-Focused Intervention for Reducing Family Violence and Symptoms in Children
Status: RECRUITING
Conditions: Intimate Partner Violence|Child Maltreatment
Interventions: BEHAVIORAL: Fathers for Change|BEHAVIORAL: Duluth BIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DKK-3 rs11544814 and CFH rs10737680 Polymorphism and Protein Levels With Non Surgical Periodontal Therapy in Periodontitis Patients With and Without CAD
Status: NOT_YET_RECRUITING
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Non surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Durvalumab Given With Chemotherapy, Durvalumab in Combination With Tremelimumab Given With Chemotherapy, or Chemotherapy in Patients With Unresectable Urothelial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Unresectable Locally Advanced Urothelial Cancer|Metastatic Urothelial Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|DRUG: Cisplatin + Gemcitabine|DRUG: Carboplatin + Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Testing of Influenza Vaccine in Healthy Children 2 Months and 6 Months of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza virus vaccine (2004-2005 Formulation)|BIOLOGICAL: Influenza virus vaccine (2004-2005 Formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DRUG: Itopride hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Tibolone and Escitalopram in Perimenopausal Depression
Status: TERMINATED
Conditions: Perimenopausal Depression
Interventions: DRUG: Tibolone|DRUG: Escitalopram|DRUG: Natvia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of SAMe for Treatment-Resistant Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Depression|Bipolar Depression
Interventions: DRUG: SAMe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Minisling Suburethral Sling and Laparoscopic Buch Colposuspension
Status: COMPLETED
Conditions: Genuine Stress Incontinence
Interventions: PROCEDURE: laparoscopic burch colposuspension operation|PROCEDURE: minisling suburethral sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Once-Daily Drug Regimen for HIV-Infected Patients
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: Amprenavir|DRUG: Ritonavir|DRUG: Abacavir|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: C2-C4 Compartment Block Versus Block of Costagliola, in TEAC
Status: COMPLETED
Conditions: Somatic Pain|Neuropathic Pain
Interventions: PROCEDURE: C2-C4 compartment anesthetic block|PROCEDURE: Costagliola block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Examining the Use of a Migraine Medicine in the Treatment of Two Migraine Attacks in Patients Who Have Increased Skin Sensitivity
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: dihydroergotamine mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome
Status: COMPLETED
Conditions: Wolfram Syndrome|Diabetes Mellitus|Optic Nerve Atrophy|Ataxia
Interventions: DRUG: dantrolene sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin A for Treatment of Catocholamine Induced Finger Necrosis
Status: UNKNOWN
Conditions: Catocholamine Induced Finger Necrosis
Interventions: DRUG: Botox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Behavioral and Psychological Symptoms of Dementia: Family Caregivers (Aim 1)
Status: COMPLETED
Conditions: Alzheimer's Disease and Related Dementias
Interventions: BEHAVIORAL: PES-4-BPSD Model|BEHAVIORAL: The attention control condition
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Spinal Cord Stimulation on Gait in Patients With Parkinson´s Disease
Status: TERMINATED
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: DEVICE: Active spinal cord stimulation|DEVICE: Sham spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Transition From Selexipag to Remodulin® Then Oral Treprostinil in Symptomatic Adult PAH
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Parenteral Remodulin (treprostinil) injection|DRUG: Oral Treprostinil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentostatin Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclosporine|DRUG: pentostatin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet in Rheumatoid Arthritis (RA)
Status: ENROLLING_BY_INVITATION
Conditions: Rheumatoid Arthritis|Inflammation|Obesity|Ketogenic Dieting|Metabolic Syndrome
Interventions: BEHAVIORAL: Ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epsilon Aminocaproic Acid Vs. Tranexamic Acid Vs. Placebo for Prevention of Blood Loss in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DRUG: Tranexamic Acid|DRUG: Epsilon Aminocaproic Acid|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Evolution of Imaging Markers of Cartilage Degradation in Patients With Knee Osteoarthritis Receiving DROGLICAN
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Droglican|DRUG: Paracetamol or oral NSAIDs excluding COX2 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study of the Combination of Melphalan, Bortezomib, Thalidomide and Dexamethasone (MEL-VTD)
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Melphalan, Velcade, Thalidomide, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients
Status: TERMINATED
Conditions: HIV Infections|HIV-Associated Lipodystrophy Syndrome
Interventions: DRUG: non-nucleoside reverse transcriptase inhibitors|DRUG: nucleoside reverse transcriptase inhibitors|DRUG: protease inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Evaluating the Effects of Fexofenadine HCI 180 mg With Orange Juice Versus Placebo With Orange Juice in a Skin Wheal and Flare Challenge Model.
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Fexofenadine HCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Early Mobilization on Sleep, Physiological Parameters, and Length of Stay in ICU
Status: COMPLETED
Conditions: Early Mobilization|Sleep Quality|Critical Care|Nursing Caries
Interventions: OTHER: Early Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-inferiority of GSK Biologicals' DTPw-HBV/Hib Compared to Two Formulations of GSK Biologicals' DTPw-HBV/Hib
Status: COMPLETED
Conditions: Whole Cell Pertussis|Haemophilus Influenzae Type b|Tetanus|Diphtheria|Hepatitis B
Interventions: BIOLOGICAL: Zilbrix-Hib|BIOLOGICAL: Tritanrix™-HepB/ Hiberix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Oklahoma Parent-Child Assistance Program
Status: RECRUITING
Conditions: Substance Use Disorders|Pregnancy Related|Alcohol Use Disorder (AUD)|Alcohol Use Complicating Pregnancy, First Trimester|Alcohol Use Complicating Pregnancy, Second Trimester|Alcohol Use Complicating Pregnancy, Third Trimester|Alcohol Use Complicating Pregnancy, Unspecified Trimester|Alcohol Use Complicating Pregnancy, Childbirth, and the Puerperium|Fetal Alcohol Spectrum Disorders|Fetal Alcohol Syndrome|Drug Use Disorders|Drug Use Complicating Pregnancy, First Trimester|Drug Use Complicating Pregnancy, Second Trimester|Drug Use Complicating Pregnancy, Third Trimester|Drug Use Complicating Pregnancy, Unspecified Trimester|Drug Use Complicating Pregnancy, Childbirth, and the Puerperium|Maternal Drugs Affecting Fetus
Interventions: OTHER: Parent-Child Assistance Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Dose Prednisone Therapy in Women With Recurrent Pregnancy Loss
Status: UNKNOWN
Conditions: Recurrent Pregnancy Loss(RPL)|Recurrent Miscarriage
Interventions: DRUG: Prednisone|DRUG: Progesterone|DIETARY_SUPPLEMENT: vit D|DIETARY_SUPPLEMENT: Iron Supplement|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Th1/Tc1 Immunotherapy Following Stem Cell Transplantation in Multiple Myeloma
Status: TERMINATED
Conditions: Myeloma, Plasma-Cell|Myeloma-Multiple|Myelomatosis
Interventions: PROCEDURE: Adoptive Immunotherapy|BIOLOGICAL: Rapamycin-Generated Autologous Th1/Tc1 Cells (modified primary human T cells)|BIOLOGICAL: Th1/Tc1 Rapa Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sub-Trial of the Youth Readiness Intervention (YRI): Treatment of Control Group and Addition of Stress Biomarkers
Status: WITHDRAWN
Conditions: Anxiety Disorder|Depressive Disorder|Social Problems|Stress, Psychological|Violence, Non-accidental
Interventions: BEHAVIORAL: Youth Readiness Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A-EYE: A Mixed Quantitative and Qualitative Study to Develop and Evaluate the Application of Artificial Intelligence (AI) Methods Using Retinal Imaging for the Identification of Adverse Retinal Changes Associated With Cancer Therapies.
Status: RECRUITING
Conditions: All Comers
Interventions: OTHER: No Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Pimitespib in Combination With Imatinib in Patients With GIST (CHAPTER-GIST-101)
Status: RECRUITING
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Pimitespib|DRUG: Imatinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Researching the Useful of Barb Suture in Obese Patients Undergoing Posterior Cervical Surgery
Status: RECRUITING
Conditions: Cervical Spinal Stenosis|Posterior Cervical Spine Surgery|Barbed Suture
Interventions: PROCEDURE: posterior cervical surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sleeve Gastrectomy on Iron Intestinal Absorption in Morbidly Obese Patients
Status: COMPLETED
Conditions: Obesity|Iron Deficiency
Interventions: PROCEDURE: Sleeve gastrectomy for morbid obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Small Colorectal Polyp Removal Using Cold EMR With Hot EMR
Status: WITHDRAWN
Conditions: Colonic Polyps
Interventions: PROCEDURE: Cold endoscopic mucosal resection|PROCEDURE: Hot endoscopic mucosal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PRP vs Corticosteroid in Rotator Cuff Tendinopathy Subtypes in Arthroscopic Repair
Status: RECRUITING
Conditions: Tendinopathy
Interventions: DRUG: platelet rich plasma|DRUG: Corticosteroid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.
Status: COMPLETED
Conditions: Premature Infant|Patent Ductus Arteriosus|Hemodynamic Instability
Interventions: DEVICE: Resonance Raman Spectroscopy (RRS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVR
Status: TERMINATED
Conditions: Peripheral Artery Disease (PAD)
Interventions: DRUG: Ticagrelor|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare Pharmacokinetics, Efficacy, and Safety of CT-P17 With Humira in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate to Severe Chronic Plaque Psoriasis
Interventions: BIOLOGICAL: CT-P17|BIOLOGICAL: EU-approved Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Dose of Alfentanil for Removal of Supreme Laryngeal Mask Airway During Emergence From Desflurane Anaesthesia
Status: COMPLETED
Conditions: Airway Response
Interventions: DRUG: alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Korean Medicine for Symptomatic Lumbar Spinal Spondylolisthesis
Status: UNKNOWN
Conditions: Spondylolisthesis, Lumbosacral Region
Interventions: OTHER: Mokhuri intensive treatment|OTHER: Non-surgical conventional standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolism and Bariatric Surgery Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Resistance|Obesity
Interventions: PROCEDURE: Roux-en-Y Gastric Bypass (RYGBP)|PROCEDURE: Sleeve Gastrectomy (SG)|BEHAVIORAL: Very Low Calorie Diet (VLCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xeomin Treatment of Glabellar Lines Using OLD Versus COLD
Status: UNKNOWN
Conditions: Glabellar Frown Lines
Interventions: DRUG: IncobotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of AZD1722 on the Pharmacokinetics of Oral Midazolam in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Midazolam|DRUG: AZD1722|DRUG: AZD1722 and Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Observational Study to Learn More About the Impact of Gadoxetate Sodium-Enhanced Magnetic Resonance Imaging (EOB-MRI) When Used to Diagnose the Spread of Cancer From the Pancreas to the Liver in Japanese People Under Real-World Conditions
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Pancreatic Cancer|Liver Metastases|Gadoxetate Sodium-enhanced Magnetic Resonance Imaging
Interventions: PROCEDURE: EOB-MRI|PROCEDURE: Surgery|PROCEDURE: Open-close Laparotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Focused Ultrasound and Calcium Hydroxylapatitie Filler for Skin Laxity and Volume Restoration
Status: COMPLETED
Conditions: Skin Laxity
Interventions: COMBINATION_PRODUCT: calcium hydroxylapatite (Radiesse) and IFUS (Ulthera)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Anidulafungin Versus Comparator in Patients With Candidemia and Invasive Candidiasis
Status: COMPLETED
Conditions: Candidiasis
Interventions: DRUG: Anidulafungin|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simethicone on Screening Colonoscopy
Status: COMPLETED
Conditions: Adenoma Colon
Interventions: DRUG: Simethicone Solution|OTHER: Polyethylenglycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Real-World Safety and Effectiveness of Sotyktu (Deucravacitinib) in Patients With Moderate-to-Severe Plaque Psoriasis in Korea
Status: RECRUITING
Conditions: Moderate-to-severe Plaque Psoriasis
Interventions: DRUG: Deucravacitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega-3 Fatty Acids and Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Omega-3|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parenting Mindfully Study II
Status: RECRUITING
Conditions: Adolescent Substance Use|Adolescent Psychological Symptoms|Parent Stress|Parenting
Interventions: BEHAVIORAL: Parenting Mindfully Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Customizing First Line Chemotherapy in Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Cisplatin, Gemzar, Docetaxel, Alimta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Focus of Attention Posttraumatic Osteoarthritis
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Tear|Osteo Arthritis Knee
Interventions: OTHER: Internal focus of attention feedback|OTHER: External focus of attention feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Protease Inhibitors for the Prevention of Malaria in Ugandan Children
Status: COMPLETED
Conditions: Malaria|HIV Infections
Interventions: DRUG: Lopinavir/Ritonavir (LPV/r)|DRUG: Nevirapine (NVP)|DRUG: Efavirenz (EFV)|DRUG: 2 nucleoside reverse transcriptase inhibitor (NRTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Different Types of Exercise Training on Biochemical Markers of Insulin-dependent Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: High-intensity interval training (HIIT)|OTHER: Strength training (ST)|OTHER: ST combined with HIIT (ST+HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of NatrOVA Creme Rinse - 1% and NIX Creme Rinse in Subjects 6 Months or Older With Head Lice
Status: COMPLETED
Conditions: Pediculus Capitis Infestation
Interventions: DRUG: Spinosad|DRUG: Spinosad|DRUG: Permethrin 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab + Imprime PGG for Metastatic Non-small Cell Lung Cancer After Progression on First-Line Therapy: Big Ten Cancer Research Consortium BTCRC-LUN15-017
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Imprime PGG|DRUG: MK-3475|DRUG: Imprime PGG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LCZ696 Compared to Olmesartan in Essential Hypertensive Patients Not Responsive to Olmesartan
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: LCZ696|DRUG: Olmesartan|DRUG: Placebo of LCZ696|DRUG: Placebo of Olmesartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BIIB092 in Participants With Progressive Supranuclear Palsy
Status: TERMINATED
Conditions: Supranuclear Palsy, Progressive
Interventions: DRUG: BIIB092|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brivanib Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Brivanib alaninate|GENETIC: Polymerase chain reaction|OTHER: Iodine I 124 chimeric monoclonal antibody G250|PROCEDURE: Positron emission tomography/computed tomography|GENETIC: Protein expression analysis|OTHER: Immunohistochemistry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ULTRACET (Tramadol Hydrochloride and Acetaminophen) for the Treatment of Rheumatoid Arthritis Pain.
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: tramadol hydrochloride + acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Monopolar Versus Biopolar Radiofrequency in OA Knee Pain
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Monopolar radiofrequency|PROCEDURE: Bipolar radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT