pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease
Status: RECRUITING
Conditions: Crohn's Disease|Complex Perianal Fistula
Interventions: BIOLOGICAL: Darvadstrocel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Intravitreal (IVT) Injection of ABI-110 (AAV2.N54-VEGF Trap) in Subjects With Neovascular (Wet) Age-Related Macular Degeneration (wAMD), Including Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV)
Status: ENROLLING_BY_INVITATION
Conditions: Neovascular (Wet) AMD
Interventions: DRUG: ABI-110 Low Dose|DRUG: ABI-110 Medium Dose|DRUG: ABI-110 High Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Long COVID-19 Rehabilitation
Status: RECRUITING
Conditions: Rehabilitation|Post-Acute COVID-19 Syndrome|Post-Infectious Disorders
Interventions: BEHAVIORAL: One day course|BEHAVIORAL: Individual follow-ups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiome Transplantation (FMT) for Type 1 Diabetes
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation (FMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Strength Training and Protein Supplementation on Fitness of Institutionalized Elderly
Status: UNKNOWN
Conditions: Aging
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Strength Training|DIETARY_SUPPLEMENT: FortiFit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Learn How Well the Study Treatment Zabedosertib (BAY1834845) Works and How Safe it is Compared to Placebo in Adult Participants With Moderate-to-severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Zabedosertib (BAY1834845)|DRUG: Placebo to zabedosertib (BAY 1834845)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic Tube Compensation (ATC) for Weaning Patients With Severe Neurotoxic Snake Envenoming
Status: COMPLETED
Conditions: Snake Bite|Weaning|Mechanical Ventilation
Interventions: OTHER: ATC|OTHER: PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ensatinib Treat Second-generation ALK-TKI Resistance After Second-generation ALK-TKI Resistance
Status: RECRUITING
Conditions: The Diagnosis Was ALK Positive NSCLC|Second Generation ALK-TKI is Resistant|Efficacy of Ensatinib in This Subset of Patients
Interventions: DRUG: Ensartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serological Study of Dengue and Characterization of Immune Response in Ten Endemic and Non-Endemic Cities in Mexico
Status: UNKNOWN
Conditions: Dengue
Interventions: DIAGNOSTIC_TEST: Estimate the distribution of antibodies by serotype by Dengue virus in areas of low and high incidence of dengue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Real-World Study to Evaluate the Clinical Performance and Safety of da Vinci SP Surgical System for Single-Port Gynecological Surgeries(SPiM-RWS-GYN)
Status: RECRUITING
Conditions: Gynecological Surgeries
Interventions: DEVICE: da Vinci SP Surgical System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerance and Immunogenicity of EuCorVac-19 for the Prevention of COVID-19 in Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: EuCorVac-19|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Bortezomib as add-on Treatment in Relapsing Neuromyelitis Optica Spectrum Disorder
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of CBT and BLT in Youth With Unipolar Depression and Evening Chronotype
Status: RECRUITING
Conditions: Depression, Unipolar|Eveningness
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy for Depression|DEVICE: Bright Light Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Granulocyte-Macrophage Colony-Stimulating Factor and Zidovudine: A Phase I Study of Concurrent Administration in Patients With AIDS and Severe ARC
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Zidovudine|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma
Status: RECRUITING
Conditions: Esophageal Adenocarcinoma|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: OBP-301|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Non-Small Cell Lung Cancer|Non-Small Cell Lung Carcinoma|Nonsmall Cell Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: efineptakin alfa|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
Status: ENROLLING_BY_INVITATION
Conditions: Familial Dysautonomia
Interventions: DRUG: Matching placebo|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effect of MMT Peel Powder on Glycemic Response, Satiety, and Food Intake in Adults at Risk for Type 2 Diabetes
Status: COMPLETED
Conditions: At Risk of Type 2 Diabetes Mellitus
Interventions: OTHER: Formulation 3|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Performance Study for EDAN's COVID-19/Flu A/Flu B/RSV Test Kits on Subjects Suspected of Respiratory Infection
Status: RECRUITING
Conditions: SARS-CoV2 Infection|Influenza A|Influenza B|Respiratory Syncytial Virus (RSV)
Interventions: DEVICE: COVID-19/Flu A/Flu B/RSV Test Kit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optimal Dose of Proton Pump Inhibitors Following an Upper Gastrointestinal Bleed
Status: TERMINATED
Conditions: Upper Gastrointestinal Bleed
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of BRL 49653C in Non-insulin Dependent Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Non Insulin Dependent Oral Agent Therapy
Interventions: DRUG: BRL 49653C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Bioavailability Study of Mylan's Revefenacin Inhalation Solution
Status: COMPLETED
Conditions: Healthy Volunteers Bioavailability Study
Interventions: DRUG: Revefenacin Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Supplement for Weight Management in Obese and Overweight Individuals
Status: COMPLETED
Conditions: Overweight and Obesity|Men|Women
Interventions: DIETARY_SUPPLEMENT: Active Supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD9668 Relative Bioavailability
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD9668|DRUG: AZD9668|DRUG: AZD9668
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates
Status: WITHDRAWN
Conditions: Congenital Heart Disease
Interventions: DRUG: Tranexamic Acid|PROCEDURE: Acute Normovolemic Hemodilution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms
Status: UNKNOWN
Conditions: Major Depressive Disorder|Rheumatoid Arthritis
Interventions: DEVICE: Transcutaneous electrical vagus nerve stimulation|DEVICE: Sham vagus nerve stimulation|DRUG: drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Body Responses to Bean Physical Form and "Beano"
Status: COMPLETED
Conditions: Appetite and Glucose Responses
Interventions: OTHER: blended lentils|OTHER: whole lentils|OTHER: no lentils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Oral Contraceptive Hormone-free Interval Pituitary/ Ovarian Activity
Status: COMPLETED
Conditions: Hypothalamic-pituitary-ovarian Axis, Gonadotropins, Ethinyl Estradiol, Contraceptive Efficacy
Interventions: DRUG: combined oral contraceptives
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Omega-3 Replacement With Krill Oil in Disease Management of SLE
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus (SLE)
Interventions: DIETARY_SUPPLEMENT: AKBM-3031|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis
Status: COMPLETED
Conditions: Hypertension in Dialysis Patients|Fluid Overload in Dialysis Patients
Interventions: OTHER: Sodium Restricted Meals|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Breathing and Walking Treatments on Recovery Post-Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries|Brown Sequard|Central Cord Syndrome
Interventions: OTHER: Intermittent Hypoxia|OTHER: Locomotor Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intermittent, High-dose Afatinib to Determine the Maximal Tolerated Dose and Assess Activity of This Dose Against Non-small Cell Lung Cancer With T790M Mutations
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Dose escalation followed by treatment with MTD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Heart Rate Variability Biofeedback Training on Health of Intrapartum Women
Status: COMPLETED
Conditions: Mental Stress
Interventions: DEVICE: heart rate variability biofeedback Application (Eureka iDestressor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: DEVICE: tDCS|BEHAVIORAL: cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: NPC-16 Standard Dosing Regimen Group|DRUG: NPC-16 Continuous Dosing Regimen Group|DRUG: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Aldurazyme® Replacement Therapy in Patients With Mucopolysaccharidosis I (MPS I) Disease
Status: COMPLETED
Conditions: Mucopolysaccharidosis I|Hurler Syndrome|Hurler-Scheie Syndrome|Scheie Syndrome
Interventions: BIOLOGICAL: Aldurazyme (Recombinant Human Alpha-L-Iduronidase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bovine Intestinal Alkaline Phosphatase (bIAP) During Heart Surgery
Status: COMPLETED
Conditions: Inflammation
Interventions: DRUG: bIAP bolus and 8h infusion|DRUG: placebo bolus and 8h infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Study of the Antitumoral Activity of Denosumab in the Pre- Operative Setting of Early Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm Female|Stage I Breast Cancer|Stage II Breast Cancer|Hormone Receptor Negative Neoplasm|Hormone Receptor Positive Tumor
Interventions: DRUG: Denosumab 120 MG/1.7 ML Subcutaneous Solution [XGEVA]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Intravenous Acetaminophen Vs Placebo for the Treatment of Endotoxin-Induced Fever in Healthy Adult Males
Status: COMPLETED
Conditions: Fever
Interventions: DRUG: IV Placebo|DRUG: IV Acetaminophen|BIOLOGICAL: Reference Standard Endotoxin (RSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Replacement on Insulin Sensitivity
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DRUG: Ergocalciferols|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Watch and Wait for NeoAdjuvant Concurrent Radiochemotherapy Combined With Camrelizumab in Patients With Resectable ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: Neoadjuvant Radiotherapy|DRUG: Neoadjuvant Chemotherapy|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia
Status: COMPLETED
Conditions: Endotoxemia|Inflammation|Multi Organ Dysfunction Syndrome|Sepsis
Interventions: DRUG: GM-CSF|DRUG: IFN-Y|OTHER: E.coli endotoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Techniques of Chest Physiotherapy in the Pediatric Intensive Care
Status: UNKNOWN
Conditions: Atelectasis
Interventions: DEVICE: Autogenic drainage|DEVICE: Intrapulmonary percussive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About How BAY2927088 Affects the Level of Midazolam in the Blood When Both Drugs Are Taken Together in Healthy Participants
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer|EGFR Mutation|HER2 Mutation|Healthy Volunteers
Interventions: DRUG: BAY2927088|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized Controlled Trial on Smoking Cessation and Adherence Intervention on Patients With Erectile Dysfunction
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: PROCEDURE: adherence intervention|PROCEDURE: intervention without adherence advice|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose:
Clinical trial: Clinical Trial of Anusol Ointment for Symptom Relief in Patients With Haemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids
Interventions: DRUG: Anusol|DRUG: Relief [Name]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Metformin Therapy in ADPKD
Status: COMPLETED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does CBT Improve the Perception/Impact of Cough and Breathlessness in IPF Patients
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis|Cough|Breathlessness
Interventions: BEHAVIORAL: Cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preconditioning Shields Against Vascular Events in Surgery
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm|Carotid Atherosclerosis|Critical Lower Limb Ischaemia
Interventions: PROCEDURE: Remote preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: One-Tooth One-Time (1T1T) A Straightforward Approach to Replace Missing Teeth in the Posterior Region: a Case Series
Status: UNKNOWN
Conditions: Dental Implant Failed|Dental Prosthesis Failure
Interventions: DEVICE: immediate loading of posterior implants with chairside CAD-CAM composite crown
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Telaprevir in Genotype 3 HCV
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Telaprevir|DRUG: 40 Kd Pegylated interferon alfa 2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Diseases Induced by Chlamydia Trachomatis
Status: COMPLETED
Conditions: Genital Chlamydia Trachomatis Infection
Interventions: OTHER: Testing for Ct infection immediately|OTHER: Testing for Ct infection at the end of the study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Oral N-Acetyl Cysteine in Prevention of Necrotizing Enterocolitis in Preterm Neonates With Feeding Intolerance
Status: ACTIVE_NOT_RECRUITING
Conditions: Preterm Neonates and Feeding Intolerance|Necrotizing Enterocolitis|Oral N-acetyl Cysteine
Interventions: DRUG: oral n-acetyl cysteine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy for Treatment of Adult Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT)|OTHER: Relaxation techniques and education about ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: effervescent ibuprofen tablets|DRUG: effervescent Aspirin plus Vitamin C tablets|DRUG: ibuprofen tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of the Renal Perfusion in Healthy Volunteers and Renal Transplant Recipients During an Orthostatic Stress
Status: COMPLETED
Conditions: Safe Volunteers|Kidney Transplant Recipients
Interventions: OTHER: tilt test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study, Comparing a Dose-Titration Regimen of Fulvestrant With the Approved Dosing Regimen in Postmenopausal Patients With Hormone-Responsive Advanced Breast Cancer (ABC)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detecting Pulmonary Arterial Hypertension (PAH) in Patients With Systemic Sclerosis (SSc) by Ultrasound
Status: TERMINATED
Conditions: Systemic Sclerosis|Pulmonary Hypertension
Interventions: RADIATION: Doppler ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
Status: RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: Aminolevulinic acid hydrochloride 10% topical gel with Red Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Flecainide|DRUG: Sotalol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacoeconomics and Related Patient Outcomes of Multi-dose Intravenous Acetaminophen (OFIRMEV)
Status: COMPLETED
Conditions: Prostatectomy|Pain
Interventions: DRUG: Acetaminophen (Ofirmev)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Femoral Nerve Blockade 7.5 ml of 1% Lidocaine: US Guidance Versus US Guidance With Electrical Stimulation of Peripheral Nerves (Influence of the Femoral Nerve Blockade on the Effectiveness of Small Doses of Local Anesthetic.). (EPBwEPN)
Status: UNKNOWN
Conditions: Nerve Block|Efficiency|Femoral Nerve|Ultrasonography|Minimum Effective Dose
Interventions: PROCEDURE: Femoral nerve block under ultrasound control with a electrostimulator peripheral nerves 7.5 ml 1% lidocaine|PROCEDURE: Femoral nerve blockade under ultrasound control without a peripheral nerve stimulator 7.5 ml 1% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Oxytocin Treatment of Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Withdrawal|Alcohol Dependence
Interventions: DRUG: intranasal oxytocin spray|DRUG: Intranasal Placebo Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life With Esophageal Stent Trial
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastro-esophageal Junction Cancer
Interventions: BEHAVIORAL: Home visits|BEHAVIORAL: standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioactive Surfaces vs. Conventional Surfaces in Implants Placed in Atrophic Maxilla With Simultaneous Sinus Lift
Status: COMPLETED
Conditions: Edentulous; Alveolar Process, Atrophy|Edentulous Alveolar Ridge Atrophy
Interventions: PROCEDURE: sinus lift|PROCEDURE: implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Reveal if Fibrinogen Treatment Effects Blood Clotting Better Than a Platelet Transfusion
Status: COMPLETED
Conditions: Blood Platelet Transfusion|Blood Clotting
Interventions: DRUG: Administration of platelet concentrate and taking blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Neurocognitive Outcome After Coronary Artery Bypass Surgery Using Minimal Versus Conventional Extracorporeal Circulation
Status: COMPLETED
Conditions: Coronary Artery Bypass
Interventions: PROCEDURE: Coronary artery bypass grafting with the use of minimal extracorporeal circulation|PROCEDURE: Coronary artery bypass grafting under conventional extracorporeal circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of 10-day Reverse Hybrid Therapy and 10-day Triple Therapy Plus Bismuth Therapy.
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: (panto+amox+clar+metr)+(panto+amox)|DRUG: pantoprazole+bismuth+amox+clar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of TUTI-16 in Asymptomatic HIV-1 Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: OTHER: Placebo|BIOLOGICAL: TUTI-16 (0.03mg)|BIOLOGICAL: TUTI-16 (0.1mg)|BIOLOGICAL: TUTI-16 (0.6mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relapse Prevention Study in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Iloperidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for the Use of Photodynamic Therapy in the Treatment of Seborrheic Dermatitis
Status: COMPLETED
Conditions: Seborrheic Dermatitis
Interventions: DRUG: aminolevulinic acid (ALA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effects of Remifentanil and Fentanyl on the Duration of Mechanical Ventilation of ICU Patients
Status: UNKNOWN
Conditions: Mechanical Ventilation
Interventions: DRUG: Remifentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Thorough QT (TQT) Study of TD-4208 in Healthy Subjects
Status: COMPLETED
Conditions: Cardiac Repolarization in Healthy Subjects
Interventions: DRUG: TD-4208 175 mcg|DRUG: TD-4208 700 mcg|DRUG: Placebo for TD-4208|DRUG: Moxifloxacin 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Mobile Application to Promote Self-care in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: ProFibro (Mobile application)|DEVICE: Paper booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycoprotein IIb/IIIa Inhibitors Versus Standard Therapy in Patients With Myocardial Infarction and No-reflow
Status: RECRUITING
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Glycoprotein IIb/IIIa inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of ММН-407 in the Treatment of Influenza in Outpatient Adults
Status: SUSPENDED
Conditions: Influenza
Interventions: DRUG: MMH-407|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NeoadjuVAnt muLti-agENT Chemotherapy or Patritumab Deruxtecan With or Without endocrINE Therapy for High-risk HR+/HER2- Breast Cancer - VALENTINE Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Patritumab deruxtecan|DRUG: Chemotherapy|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Of Dutasteride (AVODART) In Extending The Time To Progression Of Low-Risk, Localized Prostate Cancer In Men
Status: COMPLETED
Conditions: Neoplasms, Prostate
Interventions: DRUG: Dutasteride|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-intensity Stepped Care for Internalizing Distress
Status: COMPLETED
Conditions: Depression|Anxiety|Emotion Regulation
Interventions: BEHAVIORAL: Common Elements Toolbox|BEHAVIORAL: Doing What Matters in Times of Stress: An Illustrated Guide|BEHAVIORAL: Guided self-help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of PEAK PlasmaBlade™ to Conventional Diathermy in Abdominal Based Free Flap Breast Reconstruction
Status: COMPLETED
Conditions: Breast Reconstruction|Breast Cancer
Interventions: DEVICE: Conventional diathermy|DEVICE: PEAK PlasmaBlade™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: sorafenib|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of Vaccine Candidate MVA-MERS-S
Status: COMPLETED
Conditions: MERS (Middle East Respiratory Syndrome)
Interventions: BIOLOGICAL: vaccine candidate MVA-MERS-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Trial of Envafolimab for Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Male
Interventions: DRUG: Envafolimab with new manufacturing process|DRUG: Envafolimab with old manufacturing process
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigation of Potential Mechanisms in Stellate Ganglion Block in Individuals With Cerebral Small Vessel Disease
Status: NOT_YET_RECRUITING
Conditions: Cerebral Small Vessel Diseases
Interventions: BEHAVIORAL: Rehabilitation therapy|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Morbidity / Mortality Rates of Patients With Pulmonary Hypertension
Status: UNKNOWN
Conditions: oPAP Should be > 25mmHg in Right Heart Catheterization at Rest|There Should be Patients Who Will Undergo Non-cardiac and Non-obstetric Surgery
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Myocardial Infarction|Smoking
Interventions: DRUG: Bupropion HCl ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation Using VB-201 to Reduce Arterial Inflammation in Treated HIV - VITAL HIV Trial
Status: WITHDRAWN
Conditions: Inflammation|HIV Infection|Cardiovascular Disease
Interventions: DRUG: VB-201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Point of Care Evaluation of Novir 2019-nCoV Immunoglobulin G/ Immunoglobulin M (IgG/IgM) Antibody Test (Collodial Gold)
Status: TERMINATED
Conditions: Covid19
Interventions: DEVICE: COVID-19 SARS-CoV IgG/IgM antibody rapid test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pupillometry-guided Remifentanil Infusion Versus Conventional Administration in Children
Status: UNKNOWN
Conditions: Opioid Use
Interventions: DEVICE: Pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Methycobalamin in Early Dementia Patients With Vitamin B12 Deficiency and Hyperhomocysteinaemia.
Status: COMPLETED
Conditions: Dementia With Vitamin B12 Deficiency
Interventions: DRUG: Mecobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultrasound Cavitation Versus Whole Body Vibration on Abdominal Fat in Obese Adolescent Females
Status: NOT_YET_RECRUITING
Conditions: Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: Low caloric diet|DEVICE: Ultrasound cavitation|DEVICE: Whole body vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Management After Pelvic Reconstructive Surgery
Status: COMPLETED
Conditions: Urinary Retention Postoperative|Pelvic Organ Prolapse
Interventions: DEVICE: Plug-unplug catheter management|DEVICE: Continuous drainage catheter management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adalat XL vs Diltiazem on Proteinuria and Blood Pressure in Hypertensive Diabetic Patients
Status: WITHDRAWN
Conditions: Diabetic Nephropathies|Hypertension
Interventions: DRUG: Adalat XL|DRUG: Tiazac XC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Transversus Abdominis Plane Block to Postoperative Analgesia for Cesarean Section
Status: COMPLETED
Conditions: Obstetric Pain
Interventions: PROCEDURE: TAP block|DRUG: Morphine|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Embozene Microspheres for Uterine Fibroid Embolization (UFE)
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DEVICE: Embozene® Microspheres|DEVICE: Embosphere®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 2)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: On-site Practice Assessment|OTHER: Clinical Staff Questionnaires|OTHER: Patient Opinion Surveys|OTHER: Modular online COPD Education|OTHER: COPD in Primary Care/CAPTURE Introduction Focus Groups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Tolerability of Multiple Inhaled NVA237 Doses in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: NVA237|DRUG: NVA237|DRUG: NVA237|DRUG: NVA237|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Microwave Needle Thermoablation for Treatment of Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Biomedical TATO3® Microwave needle thermoablation device (Koelis, Grenoble, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Music-Based Interventions, Aging, Alzheimer's Disease
Status: RECRUITING
Conditions: Speech Perception|Anxiety|Social Behavior
Interventions: BEHAVIORAL: Choir|BEHAVIORAL: Group Music Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Different Applications of Dabigatran in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate pellets|DRUG: Dabigatran etexilate powder|DRUG: Dabigatran etexilate capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in Patients Undergoing Acute Minor Abdominal Surgery
Status: COMPLETED
Conditions: Acute Cholecystitis|Endothelial Dysfunction
Interventions: PROCEDURE: Remote Ischemic Preconditioning (RIPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long-term Study in Chronic Kidney Disease Patients With Hyperphosphatemia Not on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Renal Insufficiency|Hyperphosphatemia
Interventions: DRUG: ASP1585
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Teriparatide on Fracture Healing in Patients With Incomplete Atypical Femur Fractures
Status: COMPLETED
Conditions: Non Displaced Atypical Femoral Fractures
Interventions: BIOLOGICAL: Teriparatide 20 mcg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose-escalation Trial of SGN-75 in CD70-positive Non-Hodgkin Lymphoma or Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Lymphoma, Non-Hodgkin
Interventions: DRUG: SGN-75
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Absorption, Metabolism, and Route of Elimination of a Novel Class of Anti-HIV 1 Drugs (BMS-955176) in Humans.
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: BMS-955176
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LOw Level of Activity (LOLA): Education and Exercise-based Intervention for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: face-to-face protocol|OTHER: self-managed protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: DRUG: 5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica|DRUG: 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP|DRUG: 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica|DRUG: 5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exoskeleton-assisted Physiotherapy for Children With Mobility Impairments
Status: ENROLLING_BY_INVITATION
Conditions: Cerebral Palsy
Interventions: DEVICE: Trexo Plus Pediatric Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: LBH589 in Relapsed or Relapsed and Refractory Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial on the Role of Community Pharmacist in Improving Adherence and Clinical Outcomes in Post-Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction, Acute|ST Segment Elevation Myocardial Infarction|Non-ST Elevation Myocardial Infarction (nSTEMI)
Interventions: BEHAVIORAL: Patient-counseling|BEHAVIORAL: Patient self-administered questionnaire|BEHAVIORAL: Pills counts
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of LY2605541 and Glargine and Exercise in Participants With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY2605541|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standard Versus Prolonged Antibiotic Prophylaxis After Pancreatoduodenectomy (SPARROW)
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Cefuroxime|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intrauterine Administration of Autologous PBMC Modulated With IFNt on Endometrial Cell Populations
Status: RECRUITING
Conditions: Infertility
Interventions: BIOLOGICAL: Intrauterine administration of PBMC immunomodulated with IFNt
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Detection and Assessment of Therapy Response in Multiple Myeloma Using Whole-Body MRI
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: PROCEDURE: WBMRI|PROCEDURE: Positron Emission Tomography/Computed Tomography (PET/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Effects of Propylene Glycol/Glycerol Intake on Blood Parameters
Status: COMPLETED
Conditions: Metabolic Complication
Interventions: OTHER: Propylene glycol and Glycerol intake|DEVICE: Mimicking intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hotspot TCR-T: A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T)
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Epithelial Neoplasms
Interventions: BIOLOGICAL: TCR-transduced T cells|DRUG: CDX-1140|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NAC for Head Trauma-induced Anosmia
Status: TERMINATED
Conditions: Anosmia|Head Trauma
Interventions: DRUG: N Acetyl Cysteine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Hemostatic Effectiveness of Chitosan Gauze With Traditional Gauze on Open Wound on 10 Participants.
Status: COMPLETED
Conditions: Hemostasis
Interventions: DEVICE: Chitosan Gauze|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation
Status: UNKNOWN
Conditions: Stroke of Basilar Artery|Optical Coherence Tomography|Antithrombotics|Endovascular Thrombectomy
Interventions: DRUG: Unfractionated heparin|DRUG: Acetylsalicylic Acid (ASA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT