pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Use of Antagonist Versus Agonist GnRH in Oocyte Recipient Endometrium Preparation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Antagonist GnRH Cetrotide|DRUG: Agonist GnRH Acetate Triptoreline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Atelectasis in Pediatric Patients With Prone Position
Status: COMPLETED
Conditions: Pulmonary Atelectasis, Postoperative|Atelectasis, Compression
Interventions: PROCEDURE: Repetitive recruitment with PEEP|PROCEDURE: One recruitment with PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Al18F-NOTA-octreotide PET Imaging in Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Al18F-NOTA-octreotide|DEVICE: PET/CT|DEVICE: PET/MR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Intermittent Fasting in Psoriasis and Psoriatic Arthritis
Status: RECRUITING
Conditions: Psoriasis|Psoriatic Arthritis
Interventions: BEHAVIORAL: Intermittent Fasting Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DYNAMX Bioadaptor ImplanTation for the trEatment of Complex Coronary Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Chronic Total Occlusion of Coronary Artery|Bifurcation of Coronary Artery|Multi Vessel Coronary Artery Disease|Long Lesions Coronary Artery Disease
Interventions: DEVICE: DynamX Drug-Eluting Coronary Bioadaptor System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLOSED SUCTION DRAIN VS. NO DRAIN IN ADOLESCENTS UNDERGOING PEDICLE SCREW INSTRUMENTATION FOR IDIOPATHIC SCOLIOSIS (DAISY 2018). A Randomized Clinical Trial
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Subfascial closed suction drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Cerebral Blood Flow (CBF) in Prone and Sitting Position Before and After GSP-block and Before and After Epidural Blood-patch: A Substudy of NCT03652714
Status: WITHDRAWN
Conditions: Postdural Puncture Headache|Sphenopalatine Ganglion Block
Interventions: PROCEDURE: Ganglion sphenopalatine block with local anesthetic administered on study GSPB-2018|PROCEDURE: Ganglion sphenopalatine block with placebo administered on study GSPB-2018
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Empagliflozin add-on to Insulin in Type 1 Diabetes Mellitus Over 28 Days
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Empagliflozin medium placebo|DRUG: Empagliflozin low placebo|DRUG: Empagliflozin low placebo|DRUG: Empagliflozin high placebo|DRUG: Empagliflozin medium|DRUG: Empagliflozin medium placebo|DRUG: Empagliflozin high placebo|DRUG: Empagliflozin high placebo|DRUG: Empagliflozin medium placebo|DRUG: Empagliflozin low placebo|DRUG: Empagliflozin low|DRUG: Empagliflozin high
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tobramycin Injection to Prevent Infection in Open Fractures
Status: RECRUITING
Conditions: Wound Infection|Fractures, Open|Surgical Site Infection
Interventions: DRUG: Tobramycin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Profile in Children With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Bifidobacterium breve|DRUG: Placebo (for Bifidobacterium breve)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Steroid, PRP,and PRP Plus Hyaluronic Acid Injection for Rotator Cuff Lesions.
Status: RECRUITING
Conditions: Rotator Cuff Lesions
Interventions: DIETARY_SUPPLEMENT: Hyaluronic acid, HA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB
Status: ENROLLING_BY_INVITATION
Conditions: Short Bowel Syndrome|Malabsorption
Interventions: DEVICE: Relizorb Enzyme Cartridge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lung Deposition of the BDP/Formoterol Combination Administered Via the NEXT DPI in Healthy, Asthmatic and COPD Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Asthma
Interventions: DRUG: BDP/formoterol NEXT DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vidaza Versus Conventional Care Regimens for the Treatment of Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Conventional Care Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Serologic Response to Porcine Circovirus Type 1 (PCV-1) in the Serum of Infants and Toddlers, Following Administration of IPV (Inactivated Poliovirus Vaccine)-Containing Vaccines
Status: COMPLETED
Conditions: Presence of Materials From PCV-1
Interventions: PROCEDURE: Serum sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KD033 (SAR445710) in Subjects With Metastatic or Locally Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: KD033 (SAR445710)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Status: RECRUITING
Conditions: Coronary Artery Disease|Stroke|Atrial Fibrillation
Interventions: PROCEDURE: Left Atrial Appendage Resection and Marshall Ligament Amputation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Stabilometry After Pressure Release of the Flexor Digitorum Brevis Muscle Versus a Non-emission Laser.
Status: COMPLETED
Conditions: Balance|Manual Therapy|Foot|Myofascial Pain Syndrome|Myofascial Trigger Point
Interventions: OTHER: Preassure release|OTHER: Non-emision laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Regulation of FGF21 by Nutritional Challenges
Status: COMPLETED
Conditions: Fasting|Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: BEHAVIORAL: Fasting|BEHAVIORAL: Fasting|BEHAVIORAL: Diet|DIETARY_SUPPLEMENT: oral carbohydrate challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Meloxicam Suspension Versus Diclofenac Suspension or Nimesulide Suspension in Patients With a Diagnosis of Acute, Non-bacterial Pharyngitis, Pharyngotonsillitis or Laryngitis
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: Meloxicam|DRUG: Diclofenac|DRUG: Nimesulide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMPAS (Clinical Otitis Media & Pneumonia Study): Pneumonia & Acute Otitis Media (AOM ) Efficacy Study of the Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: Havrix|BIOLOGICAL: Engerix-B|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: GSK Biologicals' DTPa-IPV/Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Squamous Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Sotorasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Testing a Noninvasive Cryolipolysis Device Versus a High Intensity Focused Ultrasound Device for Fat Reduction
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominal Fat
Interventions: DEVICE: High Intensity Focused Ultrasound Device|DEVICE: Noninvasive Cryolipolysis Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Hyperbaric Oxygen Therapy for Radiation Dermatitis in Patients With Localized Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Radiation Dermatitis
Interventions: DEVICE: hyperbaric oxygen chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD)
Status: COMPLETED
Conditions: Crohn Disease|Pediatric Crohns Disease
Interventions: DRUG: Azithromycin|DRUG: Metronidazole|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Proprioceptive Training With Routine PT on Gross Motor Function in Spastic Quadriplegic CP
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Proprioceptive Training|OTHER: Routine Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS Treatment in Patients With General Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|DEVICE: placebo sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Dabrafenib + Trametinib for AJCC Stage IIIB-C BRAF V600 Mutation Positive Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Advanced LKB1-inactive Lung Adenocarcinoma
Interventions: DRUG: Metformin Hydrochloride|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed|DIETARY_SUPPLEMENT: Fasting-mimicking diet|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radial Versus Femoral Access for Superselective Embolization of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Hepatocellular Carcinoma Non-resectable
Interventions: PROCEDURE: Radial TAE - Bland embolization with 40-100 Microparticles|PROCEDURE: Transfemoral TAE - Bland embolization with 40-100 Microparticles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VR Glasses During Induction of Labour for Pain and Anxiety Relieve
Status: UNKNOWN
Conditions: Virtual Reality|Induction of Labor Affected Fetus / Newborn|Extra Amniotic Balloon
Interventions: DEVICE: Virtual Reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Vorinostat|DRUG: bortezomib|DRUG: placebo to vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate Safety and Efficacy of BMN 111 in Children With Achondroplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Achondroplasia
Interventions: DRUG: Active BMN 111: Subcutaneous injection of recommended dose of BMN 111 based on weight-band dosing once daily.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Water Method Colonoscopy in Routine Unsedated Colonoscopy Examinations
Status: COMPLETED
Conditions: Colonoscopy Diagnostic Techniques and Procedures
Interventions: PROCEDURE: water method colonoscopy|PROCEDURE: air method colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Sarcoma
Interventions: DRUG: Lenvatinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: MRT5005|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple-Dose Study of MK-8521 in Healthy and Obese Males (MK-8521-002)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-8521 35μg|DRUG: MK-8521 100μg|DRUG: MK-8521 125μg|DRUG: MK-8521 150μg|DRUG: MK-8521 175μg|DRUG: MK-8521 200μg|DRUG: MK-8521 300μg|DRUG: MK-8521 50/72μg|DRUG: MK-8521 72/125μg|DRUG: MK-8521 100/150μg|DRUG: MK-8521 125/150μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Rehabilitation: Effects on Cognitive Functioning, Mood, Anxiety, and Quality of Life in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease COPD
Interventions: OTHER: Extensive Pulmonary Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy
Status: COMPLETED
Conditions: SGLT2 Inhibitors, First Time Use|Type2 Diabetes|Fasting in Ramadan
Interventions: DIAGNOSTIC_TEST: HbA1c, serum creatinine, eGFR urine analysis and serum electrolyte Na and K
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Oxytocin on Approach-avoidance Tendencies to Social and Non-social Stimuli
Status: COMPLETED
Conditions: Basic Science
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of POC Pocket Ultrasound in the Estimation of Left and Right Atrial Pressures
Status: WITHDRAWN
Conditions: Heart Failure|Acute Decompensated Heart Failure
Interventions: DEVICE: General Electric (GE) VScan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IV Melanoma|Stage III Melanoma|Advanced Melanoma
Interventions: DRUG: Pembrolizumab with All-Trans Retinoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-finding and Feasibility Study for a Prolonged 13C-octanoate Breath Test for Gastric Emptying
Status: COMPLETED
Conditions: Healthy|Gastric Emptying
Interventions: DIAGNOSTIC_TEST: 13C-octanoate breath test for gastric emptying
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Scheduled Intake
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: High caloric, high protein ONS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With DWC202001 and DWC202002 in Healthy Male Adults
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: DWP16001|DRUG: DWC202001+DWC202002|DRUG: DWP16001+DWC202001+DWC202002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Perfusion Patterns of the Sigmoid Colon During Elective Open Abdominal Aortic Aneurysm Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DIAGNOSTIC_TEST: visible light spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Targeting ER Stress in Vascular Dysfunction
Status: TERMINATED
Conditions: Vasodilation|Arterial Stiffness
Interventions: DRUG: Acetylcholine|DRUG: Sodium Nitroprusside|DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Amiodarone, Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DRUG: amiodarone|DRUG: Lidocaine|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Hospital Policy of Tranexamic Acid Use to Reduce Transfusion in Major Non-cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Non-cardiac Surgeries
Interventions: DRUG: Tranexamic acid (TXA)|DRUG: Placebo (0.9 % Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Enzalutamide Pharmacokinetics and Pharmacodynamics, and Related Changes After Drug Switch
Status: COMPLETED
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: HC1119
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Zemplar Injection in Decreasing iPTH Levels in Pediatric ESRD Subjects on Hemodialysis
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|End Stage Renal Disease
Interventions: DRUG: paricalcitol injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability, and Immunogenicity of V591 (COVID-19 Vaccine) in Healthy Participants (V591-001)
Status: TERMINATED
Conditions: Coronavirus Disease (COVID-19)
Interventions: BIOLOGICAL: V591|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Aggressive Hydration With Lactated Ringer's Solution Versus Plasma Solution for the Prevention of Post ERCP (Endoscopic Retrograde Cholangiopancreatography) Pancreatitis
Status: RECRUITING
Conditions: Pancreatic Disease
Interventions: DRUG: Plasma solution-A Inj.|DRUG: Hartmann Solution inno.N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: PLAN|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Enhancing And Supporting Early Development to Better Children's Lives (EASEL) Trial
Status: COMPLETED
Conditions: Child Development
Interventions: BEHAVIORAL: The EASEL (Enhancing And Supporting Early Development to Better Children's Lives) Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Residual Curarisation at Arrival in the Post-anesthesia Care Unit
Status: COMPLETED
Conditions: Postoperative Residual Curarisation|Postoperative Hypoxemia|Postoperative Airway Obstruction
Interventions: PROCEDURE: neuromuscular transmission monitoring|PROCEDURE: Pulse oximetry measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cholinergic Anti-inflammatory Pathway in Prevention & Treatment of the SIRS in Patients With Jaundice After Operation.
Status: UNKNOWN
Conditions: Systemic Inflammatory Response Syndrome|Jaundice, Obstructive
Interventions: DRUG: neostigmine methylsulfate，raceanisodamine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short vs Prolonged Antibiotic Treatment for Hospitalized Hemato-oncology Patients With Febrile Neutropenia
Status: UNKNOWN
Conditions: Fever|Febrile Neutropenia
Interventions: DRUG: Piperacillin/tazobactam|DRUG: Ceftazidim|DRUG: Meropenem|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: BLI400 Laxative|DRUG: Lubiprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High-Selenium Brassica Juncea, Irinotecan, and Capecitabine in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: high-selenium Brassica juncea|DRUG: capecitabine|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Treatment of Pegylated Interferon Alfa 2a(Pegasys®) in the Korean Chronic Hepatitis B(CHB) Adults
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Shotblocker and Cold Massage on Pain, Crying Time and Physiological Parameters in Babies
Status: ACTIVE_NOT_RECRUITING
Conditions: Vaccine|Pain
Interventions: OTHER: Cold Massage Group|OTHER: ShotBlocker© Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Feasibility Study of Cell Therapy in Treatment of Spinal Cord Injury
Status: WITHDRAWN
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: Intravenous and intrathecal human umbilical cord tissue-derived mesenchymal stem cells and bone marrow mononuclear cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Consent Methods Performed According to Intelligence Types on Anxiety Associated With Third Molar Surgery
Status: COMPLETED
Conditions: Dental Anxiety
Interventions: BEHAVIORAL: Informed consent|PROCEDURE: Third molar surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Crisaborole Ointment for Skin Toxicity Induced by Cetuximab
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer|Cetuximab|Skin Toxicity
Interventions: DRUG: Crisaborole Ointment|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wich is the Best Dressing in Wounds by Primary Surgery of THA and / or TKA?
Status: COMPLETED
Conditions: Occlusive Dressings|Nursing|Knee Surgery|Hip Surgery
Interventions: DEVICE: Aquacel Surgical®|DEVICE: Mepilex Border post-op®|DEVICE: Opsite post-op visible®|DEVICE: Urgotul ABSORB border silicona®|DEVICE: Conventional dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vinorelbine and/or Gemcitabine in Treating Older Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: vinorelbine tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An Electromyography Study Comparing the Impact of Using RMEs on Muscle Activity Among Growing Orthodontic Patients
Status: UNKNOWN
Conditions: Malocclusion
Interventions: DEVICE: Surface EMG device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assess Safety, Bio-distribution, Radiation Dosimetry and Optimize the Imaging Protocol of GEH120714 (18F) Injection in Healthy Volunteers and Participants With Relapsing and Remitting Multiple Sclerosis (rrMS).
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis (rrMS)
Interventions: DRUG: Arm 1 - GEH120714 (18F) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
Status: RECRUITING
Conditions: Colorectal Polyp|Colorectal Neoplasms|Colorectal Adenoma|Colorectal Cancer|Digestive System Disease
Interventions: DIAGNOSTIC_TEST: FIT|DIAGNOSTIC_TEST: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial the Use of Levonorgestrel-releasing Intrauterine System Versus Etonogestrel Implant in Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Levonorgestrel|DRUG: Etonogestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GLS-1027 for the Prevention of Severe Pneumonitis Caused by SARS-CoV-2 Infection (COVID-19)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumonitis|SARS-CoV Infection
Interventions: DRUG: GLS-1027|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Inhibition in Patients With Rheumatoid Arthritis and Central Sensitivity Syndromes
Status: UNKNOWN
Conditions: Fatigue Syndrome, Chronic|Fibromyalgia|Arthritis, Rheumatoid
Interventions: DRUG: citalopram|DRUG: 1 ml 0.9 % NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of Consumption of Orafti® Inulin on Bowel Motor Function in Subjects With Constipation
Status: COMPLETED
Conditions: Healthy|Constipation
Interventions: DIETARY_SUPPLEMENT: Orafti® Inulin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Turmeric, Thymus Vulgaris, Nigella Sativa and Aloe Vera as Pulpotomy Medicaments in Primary Teeth
Status: COMPLETED
Conditions: Pulpitis - Irreversible
Interventions: PROCEDURE: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Outcome of Thoracocentesis and Pigtail Catheter Drainage in Treatment of Patients With Hepatic Hydrothorax
Status: RECRUITING
Conditions: Hepatic Hydrothorax
Interventions: PROCEDURE: Thoracocentasis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intradiscal and Intra-articular Injection of Autologous Platelet-Rich-Plasma (PRP) in Patients With Lumbar Degenerative Disc Disease and Facet Joint Syndrome
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease|Facet Joint Syndrome
Interventions: BIOLOGICAL: Autologous PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human C1 Esterase Inhibitor in the Prevention of Contrast-induced Nephropathy in High-risk Subjects
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Conestat alfa|DRUG: Sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reducing Perioperative S. Aureus Transmission
Status: TERMINATED
Conditions: Staphylococcus Aureus|Health Care Associated Infection|Health Care Worker Patient Transmission
Interventions: DEVICE: Swab and decolonization using povidone-iodine cleansing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Tirzepatide (LY3298176) in Pediatric Participants With Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effectiveness of Parassacral Transcutaneous Stimulation Compared to Tibial Transcutaneous Stimulation, Home Protocol and Behavioral Therapy in the Treatment of Female Hyperative Bladder: Randomized Clinical Trial
Status: RECRUITING
Conditions: Transcutaneous Electrical Nerve Stimulation|Urgent Urinary Incontinence|Bladder Hyperactive|Women
Interventions: DEVICE: parassacral transcutaneous electrostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breath Actuated Nebulizer Study Protocol
Status: WITHDRAWN
Conditions: Asthma|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: standard nebulizer|DEVICE: breath actuated nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the No-touch Saphenous Vein Graft
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Artery Stenosis|Graft Failure|Cardiac Ischemia|Surgery
Interventions: PROCEDURE: Сoronary bypass surgery according to the I-graft method|PROCEDURE: Сoronary bypass surgery by the method of free conduit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation
Status: COMPLETED
Conditions: Cardiac Surgery|Tricuspid Valve Regurgitation
Interventions: PROCEDURE: Tricuspid valve repair|OTHER: Mitral surgery alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: SENTANTE: Fully Robotic Peripheral Endovascular Interventions
Status: RECRUITING
Conditions: Any Disease Which Requires Peripheral Endovascular Intervention
Interventions: PROCEDURE: Endovascular intervention using the SENTANTE endovascular robotic system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: CEA-Expressing Liver Metastases Safety Study of Intrahepatic Infusions of Anti-CEA Designer T Cells
Status: COMPLETED
Conditions: Liver Metastases
Interventions: BIOLOGICAL: anti-CEA 2nd generation designer T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asthma Care With Alvesco® (Ciclesonide) in Primary Care in Adults - The ACCEPT-study (BY9010/CA-102)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide|DRUG: Usual Care Inhaled Glucocorticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Redesigned Process in the Operating Room
Status: COMPLETED
Conditions: Non-operative Time|General Surgery, Above 18 Years of Age
Interventions: PROCEDURE: Patients will be inducted in the induction room|PROCEDURE: Redesigned process|DRUG: patient will be reversed with sugammadex 4mg/kg IV|PROCEDURE: STANDARD PROCESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amitriptyline and Paroxetine Treatment of Major Depression
Status: COMPLETED
Conditions: Unipolar Depression
Interventions: DRUG: amitriptyline|DRUG: paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Itraconazole, Rifampicin and Midazolam With SIM0417/Ritonavir in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cohort 1: SIM0417/ritonavir and itraconazole|DRUG: Cohort 2: SIM0417/ritonavir and rifampicin|DRUG: Cohort 3: SIM0417/ritonavir and midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Active Controlled, Safety and Tolerability Study of VRDN-001 in Participants With Thyroid Eye Disease (TED)
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: VRDN-001 10 mg/kg|DRUG: VRDN-001 3 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Systemic Microcirculation of Patients Undergoing Heart Valve Surgery
Status: RECRUITING
Conditions: Microvascular Rarefaction|Heart Valve Diseases|Extracorporeal Circulation
Interventions: PROCEDURE: Evaluation of sublingual microcirculation with side-stream dark field imaging (cytocam)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Platform Study for the Treatment of Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma (PRISM Study)
Status: COMPLETED
Conditions: NHL|DLBCL|Non-hodgkin's Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: AZD9150|DRUG: Acalabrutinib|DRUG: AZD6738|DRUG: Hu5F9-G4|DRUG: Rituximab|DRUG: AZD5153
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Product 33525 (Luliconazole Cream 1%) in Pediatric Participants With Tinea Corporis
Status: COMPLETED
Conditions: Tinea Corporis
Interventions: DRUG: Luliconazole Cream 1%|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPT-07A Injection in Patients With Acute Ischemic Stroke (AIS): A Phase III Clinical Trial
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: DRUG: SPT-07A injection|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: School Intervention to Promote Physical Activity and Reduce the Sedentary Time of Low-income Children Aged 6-13 Years
Status: COMPLETED
Conditions: Physical Activity|Sedentary Behavior|Children|School-based Intervention
Interventions: BEHAVIORAL: School-based intervention to promote PA and reduce ST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Lumbar Vein Embolization for Chronic Headaches With Nutcracker Physiology
Status: NOT_YET_RECRUITING
Conditions: Chronic Headache|Nutcracker Phenomenon, Renal|Nutcracker Syndrome, Renal
Interventions: PROCEDURE: Coil Embolization of the Lumbar Vein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Remote Photoplethysmography Algorithm for Blood Pressure Pressure Assessment and Monitoring
Status: RECRUITING
Conditions: Remote Photoplethysmography , Blood Pressure
Interventions: DIAGNOSTIC_TEST: rPPG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Virtual Reality Headset and/or Aromatherapy for Patients Undergoing a Transperineal Prostate Biopsy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Virtual Reality Headset|OTHER: Aromatherapy Patch|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DTA (Dopaminergic Therapy for Anhedonia) Study
Status: COMPLETED
Conditions: Depression|Anhedonia
Interventions: DRUG: Carbidopa Levodopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis
Status: RECRUITING
Conditions: Behçet's Disease|Juvenile Psoriatic Arthritis
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Pancreatic Cancer|Hepatocellular Cancer|Mesothelioma|Breast Cancer|Gastric Cancer|Esophageal Cancer|Nasopharyngeal Cancer|Kidney Cancer|Squamous Cell Cancer of Head and Neck (SCCHN)|Non-small Cell Lung Cancer (NSCLC), Non-squamous
Interventions: DRUG: TAK-500|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Biomarkers and Safety of Dapagliflozin Concomitant With Neoadjuvant Therapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Hyperinsulinism|HER2-negative Breast Cancer
Interventions: DRUG: Dapagliflozin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain
Status: RECRUITING
Conditions: Pain, Chronic
Interventions: OTHER: Experimental: Group #1: Virtual Reality Headset|OTHER: Group 2 No Virtual Reality Headset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vertical Splitting of Muscle Layer in Lower Segment Cesarean Sections to Avoid Uterine Vessels Injury
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Transverse cutting|PROCEDURE: vertical splitting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Polycystic Ovary Syndrome|Non-Alcoholic Fatty Liver Disease|Metabolic Syndrome
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-Effectiveness of Different Treatment Options for Lower Calyceal Stones
Status: COMPLETED
Conditions: Renal Calculi
Interventions: PROCEDURE: Retrograde intrarenal surgery|PROCEDURE: Micro-PNL|PROCEDURE: Ultra-mini PNL|PROCEDURE: Mini-PNL|PROCEDURE: Standard PNL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Axial Spondyloarthritis|Systemic Lupus Erythematosus|Giant Cell Arteritis
Interventions: OTHER: COVID-19 infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Dose Escalation of Abiraterone Actetate in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Abiraterone acetate standard dose|DRUG: Abiraterone acetate escalated dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The BARF Project: A Pilot Study Using the BARF Scale to Assess CINV in Children
Status: TERMINATED
Conditions: Nausea
Interventions: BEHAVIORAL: Baxter Retching Faces (BARF) scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of EXO-CD24 in Preventing Clinical Deterioration in Patients With Mild-Moderate ARDS
Status: RECRUITING
Conditions: ARDS
Interventions: DRUG: EXO-CD24|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Treatment Driven by Early PET Response to a Treatment Not Monitored by Early PET in Patients With AA Stage 3-4 or 2B HL
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: BEACOPPesc|DRUG: BEACOPPesc - ABVD - PET2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose:
Clinical trial: Transplantation of HUC-MSCs With Injectable Collagen Scaffold for POF
Status: COMPLETED
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: HUC-MSCs Transplantation|BIOLOGICAL: HUC-MSCs with Injectable Collagen Scaffold Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: BEHAVIORAL: High Intensity Exercise|BEHAVIORAL: Moderate Continuous Exercise|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring to Measure Effect of Glycemic Index
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: Dexcom Seven® Plus Continuous Glucose Monitoring sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage II Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT