pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of Oncolytic Virus Injection (RT-01) in Patients With Extensive-Stage Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: Oncolytic Virus Injection(RT-01)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy
Status: COMPLETED
Conditions: Partial Nephrectomy|Kidney Cancer|Renal Function Aggravated
Interventions: OTHER: Dehydrated human amnion/chorion membrane|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect on HbA1c of the Initiation of CGM in Adults With Type 2 Diabetes Treated With Basal Insulin in Finland
Status: RECRUITING
Conditions: Type 2 Diabetes Treated With Insulin
Interventions: DEVICE: FreeStyle Libre 2 Flash Glucose Monitoring System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: STereotactic Body Radiotherapy (SBRT) for Oligoprogressive Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer|Oligoprogression
Interventions: RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Preliminary Application of Socket-shield Technique in Orthodontic Extraction and Fixed Orthodontic Treatment
Status: NOT_YET_RECRUITING
Conditions: Immediate Dental Implant Loading
Interventions: PROCEDURE: Socket-Shield Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Long-term Correction of Anemia With Epoetin Alfa in Early Hemodialysis Patients
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Anemia
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Alveogyl and Gelatin Sponge in the Management of Pain After Epithelialized Free Gingival Graft Harvesting
Status: UNKNOWN
Conditions: Pain, Procedural
Interventions: DRUG: Gelatin Sponge Sheet|DRUG: Alvogyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Glatiramer Acetate (Copaxone®) Study to Follow Participants From the First Original Study for Safety and Effectiveness
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety, Tolerability of GA-AT0119 in IBS-C
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: OTHER: ARM A|OTHER: ARM B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of rTMS on Neurotrophines Levels in CUD
Status: NOT_YET_RECRUITING
Conditions: Cocaine Use|Cocaine Dependence|Cocaine Abuse|Neurotropism
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Family-based Frailty Self Management Model and the Effects of the FRAIL-SM Program Among Patients With Heart Failure
Status: RECRUITING
Conditions: Frailty|Quality of Life|Self-management
Interventions: BEHAVIORAL: FRAIL-SM Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of HS-20094 Evaluating Weight Loss in Obese and Overweight Chinese Subjects
Status: RECRUITING
Conditions: Overweight and Obesity
Interventions: DRUG: HS-20094|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Stem Cell (PBSC) Mobilization in Patients With Relapsed Lymphoma Treated With Bendamustine
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Rituximab|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Why do Patients Report Lymphedema After Breast Cancer Treatment Without an Objective Measurable Swelling
Status: RECRUITING
Conditions: Breast Cancer|Lymphedema|Sensory Processing Disorder
Interventions: OTHER: Oedema measurements and sensory evaluations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Local Clinical Study for the Comparative Evaluation of Efficacy and Safety of Angal, Lozenges [Menthol] and ANTI-ANGIN® FORMULA, Lozenges, in Treatment of Patients With a Sore Throat
Status: COMPLETED
Conditions: Sore Throat
Interventions: DRUG: Angal, lozenges [menthol],|DRUG: ANTI-ANGIN® FORMULA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Digital Workflow for Complete Dentures - A Crossover Study
Status: NOT_YET_RECRUITING
Conditions: Complete Edentulism
Interventions: PROCEDURE: Sequence in receiving the fabricated dentures made using the conventional and partial digital method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Self-administration of Patients Own Drugs During Hospital Stay
Status: COMPLETED
Conditions: Patient Involvement|Medication Errors|Self Administration|Medication Adherence|Patient Satisfaction|Health Economics
Interventions: OTHER: Patient involvement in administration of drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam
Status: COMPLETED
Conditions: Plasmodium Vivax Malaria
Interventions: DRUG: Chloroquine|DRUG: Dihydroartemisinin/Piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard or Convalescent Plasma in Patients With Recent Onset of COVID-19 Respiratory Failure
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Standard Therapy Protocol (STP)|OTHER: STP + Standard Plasma (SP)|OTHER: STP + COVID-19 Convalescent Plasma (CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Palliative Care Intervention for Advanced Cancer Patients and Their Caregivers -Educate Nurture Advise Before Life Ends (ENABLE III)
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: BEHAVIORAL: Later entry group|BEHAVIORAL: Early palliative care intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk
Status: RECRUITING
Conditions: Malnutrition|Hepatitis B,Chronic|Acute-On-Chronic Liver Failure|Nutrition Support
Interventions: DIETARY_SUPPLEMENT: Individual nutritional support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mg Induced Changes From Day 0 to Day 28 on Serum and Urine Bone Metabolic Parameters in 70 y Old Females (no 50).
Status: COMPLETED
Conditions: Unspecified Disorder of Bone Density and Structure
Interventions: DIETARY_SUPPLEMENT: Oral magnesium substitution|DIETARY_SUPPLEMENT: Placebo tablets without magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Looking at Cardiovascular Effects of Exenatide, Its Blood Pressure Lowering Effect and Its Mechanisms
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Exenatide|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection
Status: TERMINATED
Conditions: Adnexal Mass|Germline BRCA1 Gene Mutation|Germline BRCA2 Gene Mutation|Hereditary Breast and Ovarian Cancer
Interventions: OTHER: OVA360
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis
Status: TERMINATED
Conditions: Coronary Artery Stenosis|Coronary Artery Disease
Interventions: DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alisertib in Adults With Nonhematological Malignancies, Followed by Alisertib in Lung, Breast, Head and Neck or Gastroesophageal Malignancies
Status: COMPLETED
Conditions: Advanced Nonhematological Malignancies|Non-Small Cell Lung Cancer|Small Cell Lung Cancer|Metastatic Breast Cancer|Head and Neck Squamous Cell Carcinoma|Gastroesophageal Adenocarcinoma
Interventions: DRUG: MLN8237 (Alisertib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled Trial of BMS-275291 Given Daily for 12 Months to Women With Stage 1c-IIIA Breast Cancer Receiving Adjuvant Chemotherapy and/or Hormonal Therapy
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: BMS-275291
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Loading of Midazolam or Dexmedetomidine on Hemodynamics
Status: WITHDRAWN
Conditions: Knee Injuries
Interventions: DRUG: dexmedetomidine group|DRUG: midazolam group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ready for Change: Enhancing Motivational Engagement Prior to IIPT
Status: ENROLLING_BY_INVITATION
Conditions: Chronic Pain
Interventions: BEHAVIORAL: MET-based therapy|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of TJ210001 Administered in Subjects With Relapsed or Refractory Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor|Metastatic Cancer|Advanced Cancer
Interventions: DRUG: TJ210001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mycophenolic Acid Monotherapy in Recipients of HLA-identical Living-Related Transplantation
Status: TERMINATED
Conditions: Kidney Transplantation
Interventions: DRUG: Mycophenolic Acid|DRUG: Standard of Care: CNI and MPA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Outcomes After AMIC Treatment for Talus Osteochondral Lesion Trattamento Artroscopico Delle Lesioni Osteocondrali Dell'Astragalo Con Tecnica AMIC
Status: RECRUITING
Conditions: Talar Osteochondral Defect of Ankle|Pain|Arthroscopy
Interventions: OTHER: AT-AMIC (arthroscopic talus autologous matrix induced chondrogenesis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation
Status: COMPLETED
Conditions: Retinal Oxygenation|Retinal Blood Flow
Interventions: DRUG: 100% oxygen breathing|DRUG: 15% oxygen in N2 breathing|DRUG: 12% oxygen in N2 breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Study Regarding Preventive Jaw- and Swallowing Intervention for Patients With Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Neoplasm|Trismus|Deglutition Disorders
Interventions: BEHAVIORAL: Preventive intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Nivolumab|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PHase IV Clinical Trial of Ceftriaxone Sodium and Sulbactam Sodium for Injection (CRO-SBT)
Status: COMPLETED
Conditions: Respiratory Tract Infections|Urinary Tract Infections in Children
Interventions: DRUG: Ceftriaxone Sodium and Sulbactam Sodium for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Iron Absorption Mechanism From Ferrous Fumarate With GOS
Status: COMPLETED
Conditions: Low Iron Stores
Interventions: DIETARY_SUPPLEMENT: nutritional iron (14 mg) supplement in form of ferrous fumarate|DIETARY_SUPPLEMENT: ferrous fumarate + 15 g GOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of Grazoprevir and Elbasvir in Patients With Chronic Genotype 1 HCV and HIV Co-infection
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: grazoprevir and elbasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and PD Parallel Study After Multiple Dose, Intravenous Administration of Two Epoetin Alfa, Eritromax and Eprex, in Healthy Subjects.
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sensory-Play Based (SenPlay) Intervention for Young Children With or At Risk for ADHD
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: Sensory-Play Based (SenPlay) Intervention|OTHER: Spontaneous, Free Play
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Immunogenicity Study of GSK Biologicals' Pandemic Influenza Candidate Vaccine (H1N1) (GSK2340272A)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Pandemic influenza vaccine GSK2340272A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Chemotherapy and Bemcentinib for Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Cancer of Pancreas
Interventions: DRUG: Bemcentinib|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Prednisolone Acetate 0.5% Cream Versus Betamethasone Valerate 0.1% Cream in Cortisosensitive Dermatosis
Status: UNKNOWN
Conditions: Dermatitis, Atopic|Dermatitis, Contact|Dermatitis, Seborrheic|Psoriasis
Interventions: DRUG: 0.5% prednisolone acetate cream|DRUG: 0.1% betamethasone valerate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Battery-preserving Stimulation Patterns for Deep Brain Stimulation
Status: COMPLETED
Conditions: Parkinsons Disease|Essential Tremor
Interventions: DEVICE: Biphasic DBS stimulation|OTHER: Unified Parkinson's Disease Rating Scale|OTHER: Tremor Rating Scale|DEVICE: Kinesia accelerometer|DEVICE: Trigno wireless system|OTHER: GaitRite walking assessment.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Investigation of Clinical Effectiveness of Propolis Extracts as Food Supplements in Patients With SARS-CoV-2(COVID-19)
Status: UNKNOWN
Conditions: SARS-CoV2 Infection
Interventions: DIETARY_SUPPLEMENT: propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study on Efficacy and Safety of Topiramate in Treatment of Obese Subjects With Dyslipidemia
Status: TERMINATED
Conditions: Obesity|Hyperlipidemia|Hypertriglyceridemia
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic Rhinitis
Status: RECRUITING
Conditions: Chronic Rhinitis
Interventions: DRUG: Azelastine (137 mcg/spray) Nasal Spray and Mometasone (50 mcg/spray) Nasal Spray|DRUG: Mometasone Nasal Irrigation (1 mg capsule)|DRUG: Mometasone (1 mg) and Azelastine (1 mg) Nasal Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of 22 and 25 Gauge ProCore EUS-guided Biopsy in Pancreatic Mass
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DEVICE: 22 gauge ProCore needle biopsy|DEVICE: 25 gauge ProCore needle biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pink and White Esthetic Scores of Polymer-infiltrated-ceramic-network and Lithium Disilicate Implant Hybrid Abutment Crowns
Status: UNKNOWN
Conditions: Dental Implants
Interventions: OTHER: PICN (VITA Enamic) hybrid abutment crown|OTHER: Lithium disilicate (IPS e.max) hybrid abutment crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unified Protocol for Children: A Randomized Controlled Trial for the Portuguese Population
Status: COMPLETED
Conditions: Anxiety Disorders|Mood Disorders|Emotional Disorder|Emotional; Disorder, Childhood, With Anxiety and Fearfulness|Child Mental Disorder|Parenting
Interventions: BEHAVIORAL: Emotion Detectives: Unified protocol for transdiagnostic treatment of emotional disorders in children (UP-C)|OTHER: ABC of Emotions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iloprost-Study: Comparison of Nitric Oxide to Iloprost (Ventavis) for Treatment of Pulmonary Hypertension in Children After Cardiopulmonary Bypass Surgery
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: aerosolized iloprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search of Biomarkers of Mineralocorticoid Receiver Activity : the Value of Neutrophil Gelatinase Associated Lipocalin (NGAL)in Serum or Urine in Human
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: PROCEDURE: Urinary and blood lipococalin levels determination|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Defining Adolescent Nausea Through Brain Imaging and Neurostimulation Response
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DEVICE: Active Auricular Neurostimulation|DEVICE: Sham Auricular Neurostimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Vitamin D Supplementation on Fetomaternal Outcomes in LTBI Pregnant Females
Status: COMPLETED
Conditions: Maternal and Child Health
Interventions: DIETARY_SUPPLEMENT: Vitamin-D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Diaphragmatic and Iliopsoas Myofascial Release in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain, Recurrent
Interventions: OTHER: Experimental: Diaphragmatic and İliopsoas Myofascial Release Techniques|OTHER: Sham Comparator: Sham Myofascial Release Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antihypertensive and Cardioprotective Evaluation of a Functional Olive Oil
Status: RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Optimized oil group|DIETARY_SUPPLEMENT: Functional oil group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures
Status: COMPLETED
Conditions: Chronic Liver Disease|Thrombocytopenia
Interventions: DRUG: Lusutrombopag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diverting Ileostomy and Anal Functional Outcomes After Anus Preservation Surgery
Status: UNKNOWN
Conditions: Diverting Ileostomy|Middle and Low Rectal Cancer|Functional Outcome|Stoma Complications
Interventions: PROCEDURE: Diverting ileostomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Near-infrared Radiation-transcranial Photobiomodulation for Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder|Oxidative Stress
Interventions: DEVICE: NIR-tPBM|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intrathecal Injection for ALS
Status: SUSPENDED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: AlloRx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurosurgery Patient Outcomes in Treating Spinal Disorders
Status: COMPLETED
Conditions: Symptomatic Lumbar Disc Herniation|Symptomatic Grade I Lumbar Spondylolisthesis
Interventions: PROCEDURE: Lumbar Discectomy|PROCEDURE: Single-level lumbar fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acceptability of Exoskeleton Assisted Walking for Persons With Mobility Issues Due to Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Pathologic Processes|Sclerosis|Autoimmune Diseases of the Nervous System|Demyelinating Autoimmune Diseases, CNS|Autoimmune Diseases
Interventions: BEHAVIORAL: Standard Exercise Training|DEVICE: Phoenix Exoskeleton suit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pocket Sized Carotid Stenosis Screening by Junior Doctors
Status: COMPLETED
Conditions: Ischemic Attack, Transient|Transient Ischemic Attack|Stroke|Cerebrovascular Accident|Cerebrovascular Apoplexy
Interventions: PROCEDURE: Bed-side pocket size ultrasound imaging|PROCEDURE: High frame rate tracking doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Abnormal Vascular Flow
Interventions: DRUG: Racemic ketamine|DRUG: S-ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outcomes Comparison of Chronic Immune Thrombocytopenic Purpura (ITP) Patients Switched to Eltrombopag and Romiplostim
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura
Interventions: BIOLOGICAL: Eltrombopag|BIOLOGICAL: Romiplostim
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Incision Angle of Mediolateral Episiotomy at 40 and 60 Degrees
Status: UNKNOWN
Conditions: Obstetric Labor Complications
Interventions: PROCEDURE: episiotomy|PROCEDURE: episiotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alpha 1 Anti-Trypsin (AAT) in Treating Patients With Acute Graft-Versus-Host Disease GVHD)
Status: COMPLETED
Conditions: Graft-Versus-Host Disease (GVHD) Acute on Chronic
Interventions: DRUG: Alpha 1-Proteinase Inhibitor, Human 1 MG [Glassia]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors
Status: NOT_YET_RECRUITING
Conditions: Surgical Procedure, Unspecified|Postoperative Complications|Hyperlactatemia|Abdomen Disease
Interventions: GENETIC: Genetic analysis of polymorphism of membrane receptors involved in lactate transport
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata|Alopecia Totalis|Alopecia Universalis
Interventions: DRUG: ATI-50002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Phase II Study of Bardoxolone Methyl in Patients With Chronic Kidney Disease and Type 2 Diabetes; TSUBAKI Study
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes
Interventions: DRUG: RTA 402|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Safety of the Prolonged Down-regulation Protocol for Controlled Ovarian Hyperstimulation
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Triptorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock
Status: RECRUITING
Conditions: Septic Shock|Acute Kidney Injury
Interventions: DEVICE: Combined HA380 hemoadsorption and continuous veno-venous hemodiafiltration (CVVHDF) with Oxiris®-AN69 membranes|DEVICE: Continuous veno-venous hemodiafiltration (CVVHDF) with Oxiris®-AN69 membranes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Gemcitabine Metabolites in Blood and Urine as Predictors of Response to GemX Bladder Radiotherapy
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: OTHER: sample collection|OTHER: sample collection|OTHER: Sample Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Evaluation of the VIPUN Balloon Catheter 0.1
Status: COMPLETED
Conditions: Healthy|Motility Disorder|Gastric Emptying
Interventions: DEVICE: VIPUN Balloon Catheter 0.1 deflated|DRUG: Codeine Phosphate|DRUG: Placebo|DEVICE: VIPUN Balloon Catheter 0.1 inflated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injury
Interventions: BEHAVIORAL: MOTIFS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Effects of Antiischemic Drug Therapy in Silent Ischemia
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: DRUG: bisoprolol|DRUG: amlodipine|DRUG: molsidomine|DRUG: acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: 75 mg linzagolix tablet|DRUG: 200 mg linzagolix tablet|DRUG: Add-back capsule (E2 1 mg / NETA 0.5 mg)|DRUG: Placebo tablet to match 75 mg linzagolix tablet|DRUG: Placebo tablet to match 200 mg linzagolix tablet|DRUG: Placebo capsule to match Add-back capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Clinical Performance and Safety of the Ambu®AuraGainTM Laryngeal Mask in Children Undergoing Surgery in the Supine and Prone Position - A Prospective, Noninferiority Clinical Trial
Status: COMPLETED
Conditions: Bone Marrow Examination|Urologic Surgical Procedures|Orthopedic Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Designed to Determine if the Pharmacokinetic Disposition of Inhaled Insulin Exposure is the Same for Asthmatics and Non-asthmatics
Status: COMPLETED
Conditions: Asthma|Diabetes Mellitus
Interventions: DRUG: Technosphere Insulin Inhalation Powder|DRUG: Salbutamol (Albuterol)|DRUG: Methacholine chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody|DRUG: Bevacizumab|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Gadobutrol (Gadovist, Gadavist, BAY86-4875)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Analgesic Efficacy of the Pectoral Nerves Block Versus Local Anesthetic Infiltration After Mastectomy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: OTHER: PECS block|OTHER: Local infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Pain Study for ABX-1431
Status: COMPLETED
Conditions: Neuromyelitis Optica Spectrum Disorder|Transverse Myelitis|Multiple Sclerosis|Longitudinally Extensive Transverse Myelitis
Interventions: DRUG: ABX-1431 HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AG vs mFOLFIRINOX as Neoadjuvant Therapy for Borderline Reseactable and Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Borderline Resectable Pancreatic Cancer|Locally Advanced Pancreatic Adenocarcinoma
Interventions: DRUG: Nab paclitaxel plus gemcitabine|DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetics of Topical Levofloxacin 1.5% vs Topical Moxifloxacin 0.5%
Status: UNKNOWN
Conditions: Endophthalmitis
Interventions: DRUG: Levofloxacin Ophthalmic Solution|DRUG: Moxifloxacin Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coorticosteroid Regimen in Patients With Anti-PD-1/PD-L1 Induced Pneumonitis
Status: SUSPENDED
Conditions: Lung Neoplasm Malignant|Interstitial Lung Disease
Interventions: DRUG: Prolonged glucocorticosteroid (prednisone) regimen|DRUG: Short glucocorticosteroid (prednisone) regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tumor Perfusion and Hypoxia Assessed by DCE-MRI and 18F-FMISO PET as Biomarkers of Treatment Response in Cervical Cancer
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: OTHER: DCE-MRI and 18F-FMISO PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genotypic Resistance-guided Versus Empirical Therapy for H. Pylori Eradication.
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Esomeprazole 40mg|DRUG: Clarithromycin 500mg|DRUG: Metronidazole 500 mg|DRUG: Amoxicillin 1000 MG|DRUG: Levofloxacin 500mg|DRUG: Rifabutin 150 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of Single Doses of BMS-986435 (MYK-224) in Healthy Chinese Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiome, Adiposity, and Probiotics (GMAP)
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: DIETARY_SUPPLEMENT: Probiotic - VSL#3|DIETARY_SUPPLEMENT: Placebo pill - soy protein powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection
Status: COMPLETED
Conditions: Wound Heal
Interventions: DEVICE: Electroceutical Dressing Technology-EDThi|DEVICE: Adding EDTlo (Procellera®) for 3 weeks after use of EDThi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ADC189 Tablets on Influenza A Virus Infection/Influenza B Virus Infection
Status: RECRUITING
Conditions: Safety Issues|Effect of Drug
Interventions: DRUG: 15 mg ADC189|DRUG: 45 mg ADC189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study to Assess a Trans-nasal Intestinal Potential Difference Probe
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Disease|Permeability; Increased|Crohn Disease|Inflammatory Bowel Diseases|Environmental Enteropathy
Interventions: DEVICE: IPD Probe via TNIT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effect of ATI-7505 on Gastrointestinal Transit in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ATI-7505|DRUG: Placebo|DRUG: ATI-7505|DRUG: ATI-7505
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic EUS-guided Gastroenterostomy in Advanced Periampullary Cancers
Status: RECRUITING
Conditions: Cancer Gi
Interventions: PROCEDURE: ERCP alone|PROCEDURE: ERCP +ProEUS-GE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stopping Opioid Overuse in Obstetrics To Halt Exposure Trial
Status: ENROLLING_BY_INVITATION
Conditions: Pain, Postoperative|Opioid Use
Interventions: DRUG: Liposomal bupivacaine|PROCEDURE: TAP block|DRUG: Deposition of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Urine Isoniazid Testing to Detect Nonadherence to Tuberculosis Medications in India
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis, Pulmonary|Medication Adherence
Interventions: DIAGNOSTIC_TEST: Urine isoniazid testing (IsoScreen test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Therapeutic Equivalence and Safety of Two Econazole Nitrate Cream, 1% Products in Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Econazole Nitrate Cream, 1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FET-PET-Guided Management of Pseudoprogression in Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma|Radionecrosis of Brain
Interventions: OTHER: Clinical management based on the index MRI and an additional [¹⁸F] FET PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: tFUS to Enhance Alertness and Performance
Status: NOT_YET_RECRUITING
Conditions: Reaction Time|Alertness
Interventions: DEVICE: Transcranial Focused Ultrasound|DEVICE: Transcranial Focused Ultrasound|DEVICE: Transcranial Focused Ultrasound|DEVICE: Transcranial Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic Fibrosis
Status: COMPLETED
Conditions: Cirrhosis|Liver Fibrosis|Portal Hypertension|Cystic Fibrosis|Cholestasis of Parenteral Nutrition
Interventions: OTHER: Elastometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparative Effect of Graston Technique and Petrissage Technique on Tight Trapezius Muscles in Young Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Trapezius Muscle Strain
Interventions: DIAGNOSTIC_TEST: Petrissage|OTHER: Graston Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparator Trial Using Insulin Glulisine vs. Insulin Lispro for Treatment of Gestational Diabetes
Status: COMPLETED
Conditions: Diabetes During Pregnancy
Interventions: DRUG: NPH|DRUG: Insulin LISPRO|DRUG: Insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Subacromial Decompression Surgery
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome|Subacromial Impingement Syndrome
Interventions: DEVICE: Exergames- Laptop and MIcrosoft Kinect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transanal Irrigation and Glycerol Suppositories in Treatment of Low Anterior Resection Syndrome
Status: RECRUITING
Conditions: Low Anterior Resection Syndrome|Rectal Cancer
Interventions: DEVICE: Qufora Irrisedo Cone System|DRUG: Glycerol "OBA"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PFO tRanscatether Occlusion Long-term Outcomes National Group (PROLONG) Registry
Status: COMPLETED
Conditions: Patent Foramen Ovale|Stroke, Cryptogenic|Transient Ischaemic Attack Due to Embolism|Atrial Fibrillation New Onset
Interventions: DEVICE: Septal Occluder Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Auricular Acupuncture in Depression During the Covid 19 Pandemic
Status: RECRUITING
Conditions: Depressive Symptoms|Depression|Anxiety|Insomnia|Quality of Life
Interventions: DEVICE: Auricular Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of DM934 Versus Théalose on Eye Dryness
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye
Interventions: DEVICE: DM934|DEVICE: Théalose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Leucovorin (LV)|DRUG: 5-Fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Nicotine Content Cigarettes and Tobacco Switching Behaviors
Status: COMPLETED
Conditions: Tobacco Addiction|Dual Tobacco Use
Interventions: OTHER: VLNC cigarettes|OTHER: Combusted Products|OTHER: Non-combusted products|OTHER: CN cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Suubi+Adherence4Youth
Status: RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: Financial Literacy Training (FLT) Workshops|BEHAVIORAL: Incentivized Matched Youth Savings Accounts (YSA) with income-generating activities (IGAs)|BEHAVIORAL: A manualized visual-based intervention for ART adherence and stigma reduction using multiple family group approach (Suubi Cartoon).|BEHAVIORAL: Engagement with HIV treatment-experienced role models who share lived experiences of HIV|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: What Concept of Manual Therapy is More Effective?
Status: COMPLETED
Conditions: Quality of Life|Self Efficacy|Kinesiophobia|Catastrophizing|Central Sensitisation|Anxiety|Depression|Sleep
Interventions: OTHER: Myofascial Therapy Treatments|OTHER: Passive Mobilizations Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azithromycin Treatment for Non-eosinophilic Chest Tightness Variant Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma|Chest Syndrome|Azithromycin|Effect of Drug
Interventions: DRUG: Azithromycin|DRUG: ICS/LABA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMM-BCP-01 in Mild to Moderate COVID-19
Status: UNKNOWN
Conditions: SARS-CoV2 Infection|COVID-19
Interventions: DRUG: IMM-BCP-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Probiotics BIFILACT® on Diarrhea in Patients Treated With Pelvic Radiation
Status: COMPLETED
Conditions: Cancer|Diarrhea|Abdominal Pain|Quality of Life
Interventions: DRUG: Bifilact®|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Better Evidence and Translation for Calciphylaxis
Status: RECRUITING
Conditions: Calciphylaxis
Interventions: DRUG: Vitamin K1|DRUG: Magnesium citrate|DRUG: Sodium Thiosulfate|DEVICE: High Flux Dialyser|DEVICE: Medium Cut-off Dialyser|DRUG: Placebo injection (normal saline)|DRUG: Placebo capsule (Vitamin K1)|DRUG: Placebo tablet (Magnesium citrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT