pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Multimodality Optical and Ultrasound Intravascular Imaging for Stent Optimization and Atheroma Assessment
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Stenosis|Plaque, Atherosclerotic
Interventions: DEVICE: Conavi Medical Novasight Hybrid System intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Respiratory Treatment of Patients With Moderate and Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: pressure controlled ventilator|DEVICE: Pressure Regulated Volume Controlled Ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Carotenoids Added Into Processed Foods
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Vegetable bread only|DIETARY_SUPPLEMENT: Plain bread with vegetable mayonnaise|DIETARY_SUPPLEMENT: Vegetable bread with plain mayonnaise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Adalimumab in Patients With Active Psoriatic Arthritis (PsA)
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: ODM-208|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraperitoneal Treatment of rmhTNF for CRCPM: Phase II Clinical Trial
Status: RECRUITING
Conditions: Peritoneal Metastases|Colorectal Cancer
Interventions: DRUG: Hyperthermic intraperitoneal treatment of recombinant modified human tumor necrosis factor (rmhTNF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Study of Umeclidinium/Vilanterol (UMEC/VI) in a Fixed Dose Combination With Indacaterol Plus Tiotropium
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: UMEC/VI|DRUG: UMEC/VI matching placebo|DRUG: Tiotropium|DRUG: Tiotropium matching placebo|DRUG: Indacaterol|DRUG: Indacaterol matching placebo|DRUG: Albuterol/salbutamol Metered Dose Inhaler (MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of ABT-089 in Children With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: TERMINATED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: ABT-089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ginkgo Biloba Extract in Mild Cognitive Impairment and Cerebrovascular Insufficiency
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Cerebrovascular Insufficiency
Interventions: DRUG: Ginkgo biloba standardized extract 24/6|DRUG: Ginkgo Biloba standardized extract 24/6|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Theta Burst Stimulation (cTBS) in the Treatment of Insomnia Disorder Targeting the Dentate Nucleus of the Cerebellum
Status: RECRUITING
Conditions: Insomnia Disorder
Interventions: DEVICE: transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of S-Adenosyl Methionine Treatment on Recurrence After Curative Resection of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: S-Adenosyl Methionine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
Status: COMPLETED
Conditions: Oral Surgical Procedure
Interventions: DRUG: inj dexamethasone 4mg/ml and inj lignocaine 20mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) in Ovarian Cancer Recurrence
Status: UNKNOWN
Conditions: First Recurrence of Ovarian Cancer
Interventions: PROCEDURE: Secondary citoreduction|PROCEDURE: Hyperthermic intra-peritoneal chemotherapy (HIPEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exercise and MBI on Female Students' Emotion Regulation and Inhibitory Control of Smartphone Addiction
Status: RECRUITING
Conditions: Smartphone Addiction|Mental Health Issue
Interventions: BEHAVIORAL: Exercise and Mindfulness-Based Intervention|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Versus Short Infusions of Ceftazidime in Cystic Fibrosis
Status: TERMINATED
Conditions: Cystic Fibrosis|Pseudomonas Aeruginosa|Pulmonary Exacerbation
Interventions: DRUG: ceftazidime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 28-30 Month Study Comparing Paliperidone Palmitate With Oral Risperidone for Treating Adults Diagnosed With Schizophrenia Within the Past 5 Years
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone palmitate|DRUG: oral risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Sintilimab Plus Bevacizumab Biosimilar and TACE-HAIC for HCC Patients With PVTT: A Phase-2 Clinical Trial
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Changes Between Lenticule Extraction and Small-Incision Lenticule Extraction
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: PROCEDURE: lenticule extraction|PROCEDURE: small-incision lenticule extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Patients & Effect of Antibiotics
Status: COMPLETED
Conditions: Microbiota|Anti-bacterial Agents
Interventions: DRUG: Levofloxacin|DRUG: Azithromycin|DRUG: Cefpodoxime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Chemoradiotherapy (CRT) Versus CRT Alone in Muscle-invasive Bladder Cancer (MIBC) (MK-3475-992/KEYNOTE-992)
Status: RECRUITING
Conditions: Urinary Bladder Neoplasms
Interventions: DRUG: Pembrolizumab|RADIATION: Conventional Radiotherapy (Bladder only)|RADIATION: Conventional Radiotherapy (Bladder and pelvic nodes)|RADIATION: Hypofractionated Radiotherapy (Bladder only)|DRUG: Cisplatin|DRUG: Fluorouracil (5-FU)|DRUG: Mitomycin C (MMC)|DRUG: Gemcitabine|DRUG: Placebo to Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a "Fast Track" Respiratory Therapy Clinic for Patients With Suspected Severe Sleep-Disordered Breathing
Status: UNKNOWN
Conditions: Sleep Disordered Breathing
Interventions: PROCEDURE: Fast Track
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation
Status: COMPLETED
Conditions: Fractures|Dislocations|Abscess|Anesthesia|Analgesia
Interventions: DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC)
Status: COMPLETED
Conditions: Opioid Induced Constipation
Interventions: DRUG: TD-1211|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of a Dialysate Without Acetate on Protein Energy Wasting Syndrome in Chronic Hemodialysis Patient (EASY)
Status: UNKNOWN
Conditions: End Stage Renal Disease|Hemodialysis
Interventions: DEVICE: Chlorhydric acid based acid concentrate for bicarbonate hemodialysis (medical device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of TAK-385 in the Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Placebo|DRUG: TAK-385|DRUG: TAK-385|DRUG: TAK-385|DRUG: Leuprorelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cold Application on the Subcutaneous Injection
Status: COMPLETED
Conditions: Injection Site Bruising|Bruising|Pain
Interventions: OTHER: Cold application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
Status: RECRUITING
Conditions: Ischemic Stroke|Atrial Fibrillation
Interventions: PROCEDURE: Left atrial appendage Occlusion|DRUG: DOAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ketamine and Stress in OCD
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Psychiatric Disorder
Interventions: DRUG: Ketamine 50 MG/ML|DRUG: Midazolam|DRUG: Ketamine 50 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Vincristine Sulfate Liposome For Injection In Adults With Naïve Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Adult Acute Lymphoblastic Leukemia
Interventions: DRUG: Vincristine Sulfate Liposome|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell Transplant
Status: WITHDRAWN
Conditions: Gastrointestinal Mucositis|Malignant Neoplasm
Interventions: DRUG: Palifermin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety And Tolerability Of Multiple Dose Lersivirine For 21 Days In Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Lersivirine|DRUG: Lersivirine|DRUG: Lersivirine|DRUG: Lersivirine|DRUG: Lersivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Clinical and Radiological Outcomes After Limb Reconstruction Using Monorail Fixator Over Intramedullary Nailing in Tibial Open Fractures With Bone Loss
Status: NOT_YET_RECRUITING
Conditions: Open Fracture Tibia
Interventions: PROCEDURE: intramedullary nail with Limb Reconstruction System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VE202 in Patients With Mild-to-Moderate Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis|Colitis, Ulcerative
Interventions: BIOLOGICAL: VE202|DRUG: Vancomycin Oral Capsule|OTHER: VE202 Placebo|OTHER: Vancomycin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Poorly Healed Wounds of Postoperative Incision
Status: UNKNOWN
Conditions: MSCs-PFs in Treating Poorly Healed Wounds of Postoperative Incision
Interventions: BIOLOGICAL: The pleiotropic factor derived from mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Red Clover and Lifestyle Changes to Contrast Menopausal Symptoms in Premenopausal Breast Cancer Patients Given Tamoxifen
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Promensil|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sham Controlled Study of Renal Denervation for Subjects With Uncontrolled Hypertension
Status: UNKNOWN
Conditions: Hypertension
Interventions: DEVICE: Investigational Therapy (Surround Sound)|DEVICE: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multifocal Neuromodulation in Motor and Cognitive Function of People With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Abemaciclib|DRUG: Fulvestrant|DRUG: Standard Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyaluronic Acid-enriched Transfer Medium in Single Blastocyst Transfer
Status: NOT_YET_RECRUITING
Conditions: Infertility
Interventions: BIOLOGICAL: High Hyaluronic Acid concentrations (0.5 mg/ml)|BIOLOGICAL: Low Hyaluronic Acid concentrations (0.125 mg/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CASCADE: CAnnabidiol Study in Children With Autism Spectrum DisordEr
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Oral cannabidiol 100mg/mL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Metastatic Solid Tumor|Advanced Solid Tumor|Non-small Cell Lung Cancer|SMARCA4-Deficient Tumor
Interventions: DRUG: LY4050784
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects
Status: UNKNOWN
Conditions: Pharmacokinetics|Safety
Interventions: BEHAVIORAL: Reference preparation-Reference preparation-Test Preparation|BEHAVIORAL: Reference preparation-Test Preparation-Reference preparation|BEHAVIORAL: Test Preparation-Reference preparation-Reference preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effectiveness of a Diabetes Focused Discharge Order Set Among Poorly Controlled Hospitalized Patients Transitioning to Glargine U300 Insulin
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Patient Discharge|Blood Glucose, Low|Blood Glucose, High
Interventions: OTHER: Discharge Order Set (DOS)|OTHER: Enhanced Standard Care (ESC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Injectable Platelet Rich Fibrin Versus Low-intensity Pulsed Ultrasound on Different Orthodontic Tooth Movements During Clear Aligner Therapy
Status: ENROLLING_BY_INVITATION
Conditions: Effect of Platelet Rich Fibrin Versus Low Intensity Pulsed Ultrasound During Clear Aligner Therapy
Interventions: DEVICE: low intensity pulsed ultrasound and iPRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy for Gastroesophageal Junction
Status: UNKNOWN
Conditions: Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Apatinib Capecitabine Oxaliplatin|DRUG: Capecitabine Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Striated Esophageal Motor Function Modulation in Health and Disease
Status: RECRUITING
Conditions: Dysphagia, Esophageal
Interventions: DEVICE: Concurrent manometry/impedance and fluoroscopy with and without laryngeal restriction|DEVICE: Concurrent manometry/impedance and fluoroscopy before and after six weeks of using swallow muscle exercising device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus (T1D)
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: AID System|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Carotid Intraplaque Neovascularization Combined With Stress Echo
Status: RECRUITING
Conditions: Atherosclerosis|Cardiovascular Diseases|Acute Coronary Syndrome|Ischemic Heart Disease|Myocardial Infarction|Carotid Artery Diseases
Interventions: OTHER: Carotid Contrast Enhanced Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Evaluation of Efficacy and Safety of Rituximab in Refractory CIDP Patients With IgG4 Autoantibodies
Status: COMPLETED
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Interventions: BIOLOGICAL: Rituximab (genetical recombination)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hypnosis Practice During a Semi-invasive and Painful Medical Examination in Neurology: the Electromyogram
Status: NOT_YET_RECRUITING
Conditions: Patients Requiring Electromyogram
Interventions: OTHER: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gabapentin and Donepezil Combination on Experimental Human Pain Models
Status: COMPLETED
Conditions: Pain, Neuropathic
Interventions: DRUG: Gabapentin lower dose|DRUG: Donepezil|OTHER: Placebo (Dop)|OTHER: Placebo (Gaba)|DRUG: Gabapentin higher dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: COVID-19: Collecting Measurements of Renin-angiotensin-system Markers, Such as Angiotensin-2 and Angiotensin 1-7
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Tomeka®|DRUG: "Vernonia amygdalina"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Functional Outcome of Hemiplegic Upper Extremity in Patients With Subacute Stroke After Kinesiotaping and Rehabilitation
Status: COMPLETED
Conditions: Stroke|Hemiplegia
Interventions: OTHER: Kinesiotaping|OTHER: Hand rehabilitation program|OTHER: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP16001 After Oral Administration in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DWP16001|DRUG: Placebo|DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-range Study of the Safety and Efficacy of Treatment in Adult Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AP1189, 60 mg|DRUG: AP1189, 80 mg|DRUG: AP1189, 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Chronic Exercise on UCP1 Gene in Human White Adipose Tissue
Status: COMPLETED
Conditions: Obese|Obesity
Interventions: OTHER: Effects of an eight weeks aerobic exercise followed by an eight weeks de-training period on UCP1 gene of human white adipose tissue|OTHER: Effects of an eight weeks resistance exercise followed by an eight weeks de-training period on UCP1 gene of human white adipose tissue|OTHER: Effects of an eight weeks combined (aerobic+resistance) exercise followed by an eight weeks de-training period on UCP1 gene of human white adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: CAPA-IVM Culture With Low Oxygen Tension
Status: NOT_YET_RECRUITING
Conditions: In Vitro Fertilization
Interventions: OTHER: Air Oxygen Concentration CAPA-IVM culture|OTHER: Low Oxygen Concentration CAPA-IVM culture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How a New Medicine NNC0148-0287 C (Insulin 287) Works in the Body of People With Kidney Problems
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin icodec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes
Status: RECRUITING
Conditions: Gestational Diabetes|Vascular Endothelial Function
Interventions: DRUG: Acetylcholine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and Diabetic Kidney Disease
Status: TERMINATED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: BMS-813160|DRUG: Placebo matching with BMS-813160
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Maraviroc in SARS-CoV-2 Infection (COVID-19).
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Maraviroc 300 mg|OTHER: Standard care therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
Status: RECRUITING
Conditions: Embryonal Rhabdomyosarcoma|Fusion-Negative Alveolar Rhabdomyosarcoma|Spindle Cell/Sclerosing Rhabdomyosarcoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|BIOLOGICAL: Dactinomycin|PROCEDURE: Magnetic Resonance Elastography|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Penicillin Prophylaxis in Sickle Cell Disease (PROPS)
Status: COMPLETED
Conditions: Anemia, Sickle Cell|Hematologic Diseases|Hemoglobinopathies|Infection (S. Pneumoniae)|Pneumonia
Interventions: DRUG: penicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study of BL-M07D1 Combination Therapy in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Gastric or Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: BL-M07D1|DRUG: PD-1 monoclonal antibody|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fluvoxamine on Cognition, Behavior, Symptoms and mRNA and Protein Expression in Schizophrenia Patients
Status: UNKNOWN
Conditions: SCHIZOPHRENIA 1 (Disorder)
Interventions: DRUG: fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of QVAR in Smokers With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclomethasone (QVAR)|DRUG: Beclomethasone (Clenil)|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Toclizumam Versus Dexamethasone in Severe Covid-19 Cases
Status: COMPLETED
Conditions: Pneumonia, Viral
Interventions: DRUG: Tocilizumab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of rTMS Based on Brain Activation During Language Performance in Stroke Patients With Non-fluent Aphasia
Status: COMPLETED
Conditions: Stroke|Aphasia
Interventions: DEVICE: High frequency rTMS|DEVICE: Low frequency rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine vs. In-person Delivery of Cognitive Behavioral Treatment of Insomnia: a Mixed Methods Analysis
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: BEHAVIORAL: CBT-I in person|BEHAVIORAL: CBT-I via Telemedicine|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABRIDGE: Low Molecular Weight Heparin in Bridging Patients After Mechanical Valve Replacement
Status: COMPLETED
Conditions: Mechanical Valve Replacement|Warfarin Therapy
Interventions: DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Centre, Randomised, Comparative, Blinded Wear Test of Two Adhesives on the AQUACEL® Foam Adhesive Dressing
Status: COMPLETED
Conditions: Safety and Performance of Dressing Adhesive on Healthy Volunteers
Interventions: DEVICE: AQUACEL® foam adhesive dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Added Value of Vein of Marshal Ethanol Infusion Compared to Superior Vena Cava Isolation Alone in Patients Undergoing Repeat Ablation for Recurrent Paroxysmal Atrial Fibrillation Despite Durable PV Isolation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: SVC only|PROCEDURE: SVC isolation with substrate modification and vein of Marshal ethanol infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Normothermic Perfusion in Kidney Transplantation.
Status: RECRUITING
Conditions: Kidney Transplantation
Interventions: DEVICE: Ex vivo normothermic perfusion|DEVICE: Cold preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEn
Status: RECRUITING
Conditions: Ornithine Transcarbamylase Deficiency
Interventions: GENETIC: AAVLK03hOTC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic VSL#3 for the Treatment of Gastrointestinal Symptoms Associated to Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Gastrointestinal Disease
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Brentuximab Vedotin in Combination With Cyclophosphamide, Doxorubicin (Hydroxydaunorubicin), Prednisone (CHP) in Chinese Participants With CD30-Positive (CD30+) Peripheral T-Cell Lymphomas (PTCL)
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Carcinoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BEHAVIORAL: Behavioral Intervention|OTHER: Educational Intervention|OTHER: Questionnaire Administration|PROCEDURE: Support Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Effectiveness and Safety of Risperidone in the Treatment of Adolescents With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: Beta blocker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser and Microdermabrasion Before Photodynamic Therapy for Actinic Keratoses in Field-cancerized Skin
Status: COMPLETED
Conditions: Actinic Keratosis|Sun Damaged Skin|Solar Keratosis|Solar Skin Damage
Interventions: DEVICE: Ablative Fractional Carbon Dioxide (CO2) Laser|DEVICE: Microdermabrasion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Study in Healthy Participants to Investigate the Safety and Absorption of LY2584702
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: LY2584702 Reference Formulation|DRUG: LY2584702 Test Formulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pelvic Floor Muscles Training in Group for Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: PFMT in group|OTHER: PFMT at home
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Essentiale® Paste in Patients With Gastrointestinal Symptoms in Acute or Chronic Liver Diseases
Status: COMPLETED
Conditions: Hepatic and Hepatobiliary Disorders
Interventions: DRUG: Phosphatidylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Rifabutin 150 mg Once Daily Versus Rifabutin 300 mg Thrice Weekly
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: DRUG: Lopinavir/r will be supplied by NHSO/GPO|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Nurse-led Patient-centred Intervention to Increase Written Advance Directives
Status: SUSPENDED
Conditions: Advance Care Planning|Outpatients|Palliative Care
Interventions: OTHER: serious game named Go Wish|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of YPEG-rhGH in Children With Short Stature
Status: COMPLETED
Conditions: Idiopathic Short Stature|Small for Gestational Age|Turner Syndrome
Interventions: DRUG: YPEG-rhGH|DRUG: YPEG-rhGH|DRUG: rhGH|DRUG: rhGH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Myelodysplastic Syndromes|Acute Leukemia|Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)|Chronic Myeloid Leukemia
Interventions: BIOLOGICAL: Orca-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using fMRI and sEMG to Evaluate the Effects and Mechanism on Abdominal Acupuncture Combined With Upper Limb Rehabilitation Training on Brain Plasticity of Hemiplegic Patients With Stroke
Status: UNKNOWN
Conditions: Brain Ischemia|Hemiplegic Patients With Stroke|Image Science|Electrophysiology of Neuromuscular|Abdominal Acupuncture
Interventions: OTHER: Abdominal acupuncture|OTHER: Sham abdominal acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CPAP on Symptoms of Patients With Fibromyalgia and Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Fibromyalgia|Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure Therapy (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NExT ERA: National Expertise Based Trial of Elective Repair of Abdominal Aortic Aneurysms: A Pilot Study
Status: UNKNOWN
Conditions: Aortic Aneurysm, Abdominal
Interventions: PROCEDURE: Endovascular Repair of Abdominal Aortic Aneurysm|PROCEDURE: Conventional open repair of Abdominal Aortic Aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stress Ball Use on Procedural Pain Caused by Subcutaneous Injection in Orthopedic Patients
Status: RECRUITING
Conditions: Misadventure During Injection / Vaccination
Interventions: OTHER: stress ball use during subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: pegaspargase|DRUG: thioguanine|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Role of Testosterone and Dihydrotestosterone and Which of Them Should be Inhibited in COVID-19 Patients - A Double-edged Sword?
Status: UNKNOWN
Conditions: Covid19
Interventions: COMBINATION_PRODUCT: Aerosolized 13 cis retinoic acid plus Inhalation Inhaled testosterone|DRUG: The standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of New Standards for Tobacco Products Among Dual E-Cigarette/Combusted Cigarette Users - Project 2
Status: COMPLETED
Conditions: Smoking|Smoking, Cigarette|E-Cig Use|Nicotine Dependence
Interventions: OTHER: very low nicotine content cigarettes|OTHER: normal nicotine content cigarettes|OTHER: Study e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: High Versus Standard Voltage Pulsed Radiofrequency for Cervical Nerve Roots Injection in Refractory Chronic Unilateral Cervical Radicular Pain
Status: COMPLETED
Conditions: Chronic Cervical Radiculopathy
Interventions: DEVICE: radiofrequency high voltage|PROCEDURE: standard RF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Variant (COVID-19) mRNA Vaccines
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: ABO1009-DP|BIOLOGICAL: ABO-CoV.617.2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Full dose TNK-tPA|DRUG: Half dose TNK-tPA|DRUG: Heparin|DRUG: Enoxaparin|DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
Status: COMPLETED
Conditions: Third Molar Surgery
Interventions: DRUG: Dexketoprofen Trometamol|DRUG: Dexamethasone 21-Phosphate|DEVICE: Therapeutic Elastic Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics of a Single Dose of CCH (3.36 mg) in Subjects With EFP
Status: COMPLETED
Conditions: Edematous Fibrosclerotic Panniculopathy
Interventions: BIOLOGICAL: CCH (collagenase clostridium histolyticum)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel Followed by Capecitabine Versus Concomitant Docetaxel/Capecitabine for Early Stage Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Docetaxel/Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Could Bisphenol-A Have a Role in the Etiology of Neural Tube Defects
Status: COMPLETED
Conditions: Neural Tube Defects|Bisphenol-A
Interventions: DIETARY_SUPPLEMENT: Bisphenol-A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Transcranial Direct Current Stimulation of the Primary Motor and Somatosensory Cortex on Pain Thresholds.
Status: UNKNOWN
Conditions: Healthy
Interventions: DEVICE: Active tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot, Prospective, Comparative Multicentric Study Evaluating the Effects on the Arthrosis Biomarkers, the Clinical Effectiveness, the Tolerance of an Intra-articular Injection of Hyaluronic Acid KARTILAGE CROSS Versus Placebo in Patients Suffering From Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: KARTILAGE CROSS|DEVICE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Feeding Frequency, Muscle Glycogen and Exercise Capacity in Runners
Status: COMPLETED
Conditions: Exercise
Interventions: OTHER: Regular carbohydrate feeding|OTHER: Single carbohydrate bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acetic Acid Colonoscopy Enhancement Study
Status: UNKNOWN
Conditions: Colorectal Cancer|Serrated Adenomas|Colon Nos Polypectomy Tubular Adenoma
Interventions: DRUG: Acetic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of the Combination Mometasone + Salicylic Acid in Patients With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: memotasone + salicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Toludesvenlafaxine Hydrochloride Sustained-release Tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RAD001(Everolimus) in Treating Patients With Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: everolimus|OTHER: laboratory biomarker analysis|PROCEDURE: Bone marrow aspirate/biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying the Anti-Blood-Clotting Compounds in Garlic
Status: COMPLETED
Conditions: Arteriosclerosis|Intracranial Arteriosclerosis
Interventions: DIETARY_SUPPLEMENT: garlic powder added to ambient water|DIETARY_SUPPLEMENT: garlic powder added to boiling water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Mixed Method Pilot Study for Patients With Mild Cognitive Impairment and Insomnia.
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Insomnia
Interventions: BEHAVIORAL: Empowerment-based Cognitive behavioral therapy for insomnia for MCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria
Status: COMPLETED
Conditions: Malaria|Febrile Illness
Interventions: OTHER: Testing incentive|OTHER: Conditional artemisinin combination therapy subsidy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Chemotherapytreatment of Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Neoadjuvant Chemotherapy
Interventions: DRUG: Triprilimab combined with TP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors
Status: COMPLETED
Conditions: Brain Tumors|Metastatic Disease
Interventions: DRUG: donepezil hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: XEN-45 Gel Stent Versus Trabeculectomy in Glaucoma: Gold-Standard Pathway Study (GPS)
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: XEN-45 Gel Stent|PROCEDURE: Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT