pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Pursed Lips Breathing on Chest Wall, Mobility Diaphragmatic and Exercise Tolerance in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pursed Lips Breathing|OTHER: Quiet Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy Followed By Surgery With or Without Radiation Therapy in Treating Young Patients With Stage II or Stage III Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Binge Eating Liraglutide Intervention
Status: TERMINATED
Conditions: Binge-Eating Disorder
Interventions: DRUG: Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Golimumab (CNTO 148) in Participants With Moderately to Severely Active Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: Golimumab 50 mg|BIOLOGICAL: Golimumab 100 mg|BIOLOGICAL: Golimumab 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Output in Heart Failure Patients With Mechanical Pumps
Status: TERMINATED
Conditions: Heart Failure, Systolic|Mechanical Circulatory Support|Cardiovascular Hemodynamics
Interventions: DIAGNOSTIC_TEST: preload challenge|DIAGNOSTIC_TEST: afterload challenge|DIAGNOSTIC_TEST: contractility assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Management by Hyperbaric Oxygen Therapy of Patients With Hypoxaemic Pneumonia With SARS-CoV-2 (COVID-19)
Status: UNKNOWN
Conditions: Covid-19
Interventions: COMBINATION_PRODUCT: Hyperbaric oxygen treatment (HBOT) i.e. inhalation of pressurized oxygen delivered by a hyperbaric chamber (drug/device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome|FXS|Fra(X) Syndrome
Interventions: DRUG: BPN14770|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Kanglaite Injection Phase I Study
Status: COMPLETED
Conditions: Solid Tumors Refractory To Standard Therapy|Neoplasms
Interventions: DRUG: Kanglaite Injection (KLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung MORphological Modifications Evaluated by Electrical Impedance Tomography During Preoxygenation for the Intubation of Hypoxemic Patients: Comparison of Standard Oxygenation, High Flow Nasal Oxygen Therapy, and NonInvasive Ventilation (MORPHEIT Study, an Ancillary Study of PREONIV Trial)
Status: UNKNOWN
Conditions: Adult Patients|Requiring Intubation|Hypoxemia (Defined by PaO2/FiO2( Fraction of Inspired Oxygen) Below 200)|Patient Covered by French Health Care System
Interventions: PROCEDURE: Standard oxygenation|PROCEDURE: High flow nasal oxygenation|PROCEDURE: noninvasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Virtually Supervised Mouth Rinses and Flossing
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: LISTERINE COOL MINT Antiseptic Mouthwash|OTHER: LISTERINE COOL MINT ZERO Alcohol Mouthwash|OTHER: Reach Unflavored Waxed Dental Floss|OTHER: Colgate Cavity Protection Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate Efficacy and Safety of Masitinib in Patients With Relapse or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Masitinib|DRUG: Placebo|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Darcilil Combined With AI Combined With Pyrrotinib in the Treatment of TPBC
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Darcilide +AI (letrozole/anastrozole/Exemestane) + pyrrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity
Status: RECRUITING
Conditions: Lung Cancer, Nonsmall Cell|Renal Cell Carcinoma|Melanoma|Gastric Cancer|Hepatocellular Carcinoma|Endometrial Cancer|Mesothelioma
Interventions: DIAGNOSTIC_TEST: Blood screening|DIAGNOSTIC_TEST: Tissue screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, and Efficacy of AT101 in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma
Status: RECRUITING
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: DRUG: AT101(Anti-CD19 Chimeric Antigen Receptor T cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Site Concentration of Remifentanil for Preventing QTc Interval Prolongation During Intubation in Normotensive and Hypertensive Patients
Status: COMPLETED
Conditions: Intubation, Intratracheal
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS)
Status: RECRUITING
Conditions: PIK3CA-related Overgrowth Spectrum|CLOVES Syndrome|Klippel Trenaunay Syndrome|Megalencephaly|MCAP|Macrodactyly|Vascular Malformations|Lymphatic Malformation|Venous Malformation
Interventions: OTHER: national registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative Assessment of Autologous Fat Transfer
Status: RECRUITING
Conditions: Autologous Fat Grafting
Interventions: PROCEDURE: 2-Dimensional (2-D) Photographs (Visit 1/ Follow up Visit 3-6)|PROCEDURE: 3-Dimensional (3-D) Photographs (Visit 1- 6)|PROCEDURE: Ultrasound Soft Tissue Assessment (Visit 1/ Follow up Visit 4-6)|PROCEDURE: Magnetic Resonance Imaging Volume Assessment (Visit 1/ Follow up Visit 4-6)|PROCEDURE: BREAST-QTM questionnaire (Visit 1/ Follow up Visit 4-6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers
Status: RECRUITING
Conditions: Sleep
Interventions: BEHAVIORAL: Care2Sleep|BEHAVIORAL: Sleep Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema
Status: WITHDRAWN
Conditions: Diabetic Macula Edema
Interventions: DRUG: Brolucizumab|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients
Status: COMPLETED
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: MLN0128
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Endometrial Endometrioid Adenocarcinoma|Recurrent Ovarian Carcinoma|Recurrent Ovarian Clear Cell Adenocarcinoma|Recurrent Ovarian Endometrioid Adenocarcinoma|Recurrent Uterine Corpus Cancer
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Tazemetostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Coagulation for the Prevention of Bleeding in Endoscopic Mucosal Resection of Large Sessile Colonic Polyps
Status: COMPLETED
Conditions: Adenomatous Polyp of Large Intestine
Interventions: PROCEDURE: Prophylactic use of coagulation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel Adjuvants for Peptide-Based Melanoma Vaccines
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: MDX-CTLA4 Antibody; Tyrosinase/gp100/MART-1 Peptides Melanoma Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Plus PD-1 Antibody vs TACE Alone for Unresectable HCC
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE|DRUG: PD-1 antibody|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promote Brain Resilience for the Coronavirus (COVID-19) Pandemic
Status: ACTIVE_NOT_RECRUITING
Conditions: Transcranial Direct Current Stimulation|Mental Health Issue|Public Health|Resilience, Psychological|COVID-19
Interventions: OTHER: Transcranial Alternate Current Stimulation|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Danish Nationwide Longitudinal Study on Prevalence of Periodontitis and Its Co-morbidities
Status: NOT_YET_RECRUITING
Conditions: Periodontitis|Diabetes Mellitus, Type 2|Cardiovascular Diseases|Rheumatoid Arthritis
Interventions: PROCEDURE: Periodontal treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintenance Treatment of Chidamide in Stage IV or Relapsed/Refractory Extranodal NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Rotigotine Nasal Spray for the Acute Treatment of RLS Symptoms
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Rotigotine Nasal Spray|OTHER: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Physical Training Under Normobaric Hypoxia on Oxidative Stress Level, Inflammatory State, Intestinal Damage, and Mitochondrial Metabolism in Young Males
Status: RECRUITING
Conditions: Hypoxia, Altitude
Interventions: OTHER: Exercise and environmental conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Ultrasound Therapy of Essential Tremor
Status: ACTIVE_NOT_RECRUITING
Conditions: Essential Tremor
Interventions: DEVICE: Transcranial Ultrasound Therapy (Exablate® 4000 Type 1.1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas
Status: RECRUITING
Conditions: Hyperparathyroidism, Primary
Interventions: DRUG: 18F-Fluorocholine|PROCEDURE: Positron emission tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Tibolone and Raloxifene on Bone Mineral Density in Osteopenic Postmenopausal Women (P06090)
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: tibolone|DRUG: raloxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004)
Status: RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: V940|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Axitinib Versus Sunitinib Monotherapy in Participants With Renal Cell Carcinoma (MK-3475-426/KEYNOTE-426)
Status: ACTIVE_NOT_RECRUITING
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Axitinib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Trial: Carbetocin Appropriate Rate Better Equilibrium Between Tonus (TOnus) and CIrculatioN
Status: COMPLETED
Conditions: Complications; Cesarean Section|Anesthesia; Reaction
Interventions: DRUG: Carbetocin Short-infusion|DRUG: Carbetocin Bolus application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Everolimus- and Biolimus-Eluting Stents With Everolimus-Eluting Bioresorbable Vascular Scaffold Stents
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Implantation of everolimus-eluting bioresorbable vascular scaffold stent|DEVICE: Implantation of everolimus-eluting stents|DEVICE: Implantation of biolimus-eluting stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NMDA Modulation in Major Depressive Disorder in Late- Life
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: NMDA|DRUG: Sertraline|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partially Covered Versus Uncovered Pyloro-duodenal Stents for Unresectable Malignant Gastric Outlet Obstruction. A Double Blinded Randomised Controlled Trial.
Status: COMPLETED
Conditions: Unresectable Malignant Gastric Outlet Obstruction
Interventions: OTHER: Partially covered pyloro-duodenal stent|OTHER: Uncovered pyloro-duodenal stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Bone Marrow or Peripheral Stem Cell Transplantation, and/or Biological Therapy in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisone|DRUG: teniposide|DRUG: vincristine sulfate|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Isolation of Pulmonary Veins With the Aid of Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Conventional AF ablation|PROCEDURE: LGE-MRI guided AF ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Rilpivirine|DRUG: ARV Background Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HEP-40 Chitosan for Mild to Moderately Elevated Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DEVICE: HEP-40 chitosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual Therapy and Respiratory Muscle Training on the Maximal Inspiratory Pressure in Patients With Asthma
Status: COMPLETED
Conditions: Manual Therapies|Respiratory Muscle Training|Exercise Therapy|Inspiratory Capacity|Asthma
Interventions: OTHER: Inspiratory Muscle training (IMT)|OTHER: IMT + Manual Therapy and Motor Control Exercise|DEVICE: Powerbreathe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fu's Subcutaneous Needling on Postoperative Acute Pain in Patients With Lumbar Spine Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: Fu's Subcutaneous Needling(FSN)|DEVICE: fine acupuncture needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study to Evaluate the Safety, Tolerability and PK of JIN-A02 in Patients With EGFR Mutant Advanced NSCLC
Status: RECRUITING
Conditions: EGFR Mutant Advanced Non-small Cell Lung Cancer
Interventions: DRUG: JIN-A02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin in Intracytoplasmic Sperm Injection Cycles
Status: COMPLETED
Conditions: Intracytoplasmatic Sperm Injection
Interventions: DRUG: Metformin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery
Status: RECRUITING
Conditions: Surgical Blood Loss|Transfusion-dependent Anemia|Abdomen Disease
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triheptanoin in Mc Ardle
Status: UNKNOWN
Conditions: Glycogen Storage Disease Type V
Interventions: DRUG: Triheptanoin|DRUG: Placebo oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Descriptive and Comparative Study of Respiratory Function in the Postoperative Cardiac Surgery Patient
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Atelectasis
Interventions: PROCEDURE: Lungrecruitment manoeuver in prone position.|PROCEDURE: Lungrecruitment manoeuver in supine position.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical Erythropoietin Hydrogel Formulation for Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: A hydrogel containing erythropoietin|DRUG: Hydrogel (as a part of SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Famciclovir 500 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Famciclovir 500 mg Tablets|DRUG: Famvir® 500 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immune Neoadjuvant Therapy Study of Durvalumab in Early Stage Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Patients With Chronic Widespread Pain
Status: SUSPENDED
Conditions: Chronic Widespread Pain
Interventions: PROCEDURE: Fecal Microbiota Transplantation|PROCEDURE: Sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain After Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia|Chronic Pain
Interventions: PROCEDURE: selfgrip mesh|PROCEDURE: lightweight mesh with suture fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of 4-7-8 Breathing Exercise Technique on Tinnitus
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: OTHER: 4-7-8 breathing exercise technique and informative session on tinnitus|OTHER: Informative session on tinnitus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fingerprick Autologous Blood (FAB) in Severe Dry Eye Disease (DED)
Status: UNKNOWN
Conditions: Dry Eye Syndromes
Interventions: OTHER: Fingerprick autologuos blood (FAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Multi-Level Smoking Cessation Program for High-Risk Women in Rural Communities
Status: RECRUITING
Conditions: Tobacco-Related Carcinoma
Interventions: OTHER: Best Practice|OTHER: Survey Administration|OTHER: Tobacco Cessation Counseling|OTHER: Tobacco Cessation Counseling|OTHER: Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anti-Inflammatory Effects of Pioglitazone
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Type 2 Diabetes Mellitus|Atherosclerosis
Interventions: DRUG: Pioglitazone|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NMES Role to Prevent Respiratory Muscle Weakness in Critically Ill Patients and Its Association to Changes in Myokines.
Status: UNKNOWN
Conditions: Muscle Weakness or Atrophy|Mechanical Ventilation Complication|Electrical Stimulations
Interventions: DEVICE: Neuromuscular electrical stimulation (NMES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Functional Outcomes of Botulinum Toxin A Injections to Hamstrings in Flexed Knee Gait in Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Diplegic Cerebral Palsy
Interventions: DRUG: Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Movement Control Exercises and Fascial Manipulation in Chronic Low Back Pain
Status: ENROLLING_BY_INVITATION
Conditions: Low Back Pain|Low Back Pain, Recurrent
Interventions: OTHER: FM and MCE|OTHER: FM and sham-MCE|OTHER: MCE and sham-FM|OTHER: Sham-MCE and sham-FM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microtransplantation and Checkpoint Blockade Immunotherapy for Relapsed or Refractory B Cell Lymphomas
Status: WITHDRAWN
Conditions: B Cell Lymphomas
Interventions: DRUG: Nivolumab|BIOLOGICAL: Microtransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of Orthotic Shorts for People With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Close-fitting orthotic shorts|DEVICE: Looser fitting shorts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: High Dose Vitamin C in Cardiac Surgery Patients
Status: TERMINATED
Conditions: Disorder of Vitamin C|Atrial Fibrillation|Complications Due to Coronary Artery Bypass Graft|Heart Valve Disease
Interventions: DRUG: Ascorbic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination Chemotherapy With Pazopanib in Children and Adolescents With Relapsed/Refractory Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Relapsed Pediatric Solid Tumor|Refractory Pediatric Solid Tumor
Interventions: DRUG: Pazopanib|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PK/PD Study of SHR2285 Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: SHR2285|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dietary Intervention, Gestational Weight Gain and Gestational Diabetes.
Status: COMPLETED
Conditions: Dietary Habits|Gestational Diabetes|Weight Gain|Overweight and Obesity
Interventions: BEHAVIORAL: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection
Status: UNKNOWN
Conditions: Lumbar Spinal Stenosis|Lumbar Disc Herniation|Scoliosis Lumbar Region|Lumbar Spondylolisthesis|Lumbar Disc Lesion
Interventions: DRUG: Teicoplanin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Supplemented Analgesia in Patients at High-risk of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obstructive Sleep Apnea|Analgesia|Dexmedetomidine|High-flow Nasal Cannula|Sleep Quality
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Istradefylline 20 mg or 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-field Magnetic Resonance Imaging of Pediatric COVID-19
Status: UNKNOWN
Conditions: Sars-CoV-2 Infection|Lung Fibrosis|Covid19
Interventions: DIAGNOSTIC_TEST: Low-field magnetic resonance imaging|DIAGNOSTIC_TEST: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ziprasidone on Glucose & Plasma Lipids in Diabetes (II) and Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retinal Photoreceptor Outer Segment Length Before and After Light Stimulation - a Pilot Study
Status: RECRUITING
Conditions: Macular Degeneration, Dry|Primary Open-angle Glaucoma
Interventions: OTHER: White light stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected Patients
Status: COMPLETED
Conditions: Hepatitis C|HIV Infections
Interventions: DRUG: Peginterferon alfa-2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Aldesleukin|DRUG: Cyclophosphamide|DRUG: Decitabine|BIOLOGICAL: Genetically Engineered NY-ESO-1-specific T Lymphocytes|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triciribine Phosphate Monohydrate (TCN-PM, VD-0002) in Adult Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Hematologic Malignancies|Leukemia
Interventions: DRUG: Triciribine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria
Status: RECRUITING
Conditions: Severe Malaria
Interventions: DRUG: KAE609|DRUG: IV Artesunate|DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post Marketing Surveillance Study of Dysport
Status: COMPLETED
Conditions: Blepharospasm|Hemifacial Spasm|Cervical Dystonia|Spasmodic Torticollis|Cerebral Palsy|Muscle Spasticity|Cerebrovascular Accident|Equinus Deformity|Facial Hyperdynamic Lines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bay98-7196, Dose Finding / POC Study
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Placebo|DRUG: Levonorgestrel|DRUG: Anastrozole|DRUG: Lupron / Leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: mHealth-supported Telecolposcopy for Cervical Cancer Programs in Low-resource Settings: Evaluation (mIVAA)
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DEVICE: Pocket colposcope/Mobile phone camera|OTHER: mIVAA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Nivolumab in AML in Remission at High Risk for Relapse
Status: COMPLETED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia in Remission|Blasts Under 10 Percent of Bone Marrow Nucleated Cells|Therapy-Related Myeloid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Engensis (VM202) in Patients With Charcot-Marie-Tooth Disease Subtype 1A (CMT1A)
Status: COMPLETED
Conditions: CMT
Interventions: BIOLOGICAL: Engensis (VM202)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Baracle Tab. ® Versus Baraclude Tab.® for Patients With HBeAg Chronic Hepatitis B
Status: COMPLETED
Conditions: HBeAg-Positive Chronic Hepatitis B
Interventions: DRUG: Baracle Tab.®|DRUG: Baraclude Tab.®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simulator of Pompage Technique for Physiotherapists
Status: COMPLETED
Conditions: Musculoskeletal Pain|Contracture
Interventions: OTHER: Simulator's construction|OTHER: Model Features|OTHER: Parameterization technique|OTHER: Simulator training|OTHER: Training Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Cisplatin and Radiation Therapy With or Without Hyperthermia Therapy in Treating Patients With Cervical Cancer
Status: TERMINATED
Conditions: Cervical Cancer
Interventions: DRUG: cisplatin|PROCEDURE: hyperthermia treatment|RADIATION: brachytherapy|RADIATION: external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Markers in Saliva of Patients With Burning Mouth Syndrome
Status: COMPLETED
Conditions: Burning Mouth Syndrome
Interventions: COMBINATION_PRODUCT: Laser+clonazepam|DEVICE: Laser Sham|DEVICE: Laser|DRUG: Clonazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Gallstones in Post-bariatric Surgery Patients
Status: RECRUITING
Conditions: Bariatric Surgery Candidate|Gallstone|Gallstone Attack|Gastrointestinal Quality of Life Index|Probiotics
Interventions: DRUG: Ursodoxycholic acid group|DRUG: Bifidobacterium group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography
Status: RECRUITING
Conditions: Lung Collapse
Interventions: DEVICE: Bed tilting|OTHER: Body positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure
Status: UNKNOWN
Conditions: Premature Ovarian Failure
Interventions: BIOLOGICAL: Stem Cell Preparation and Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Genakumab for Injection in Patients With Acute Gout
Status: UNKNOWN
Conditions: Acute Gout
Interventions: DRUG: Genakumab for Injection|DRUG: Placebo for Genakumab for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Adenocarcinoma|Pancreas Ductal Adenocarcinoma
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: WHNRC (Western Human Nutrition Research Center) Honey Study
Status: RECRUITING
Conditions: Postprandial Glycemia|Metabolic Stress|Cognitive Change|Satisfaction, Personal
Interventions: OTHER: Honey|OTHER: Sucrose|OTHER: Honey plus almonds|OTHER: Sucrose plus almonds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of NNC 0142-0000-0002 in Subjects With Moderately to Severely Active Crohn's Disease
Status: COMPLETED
Conditions: Inflammation|Crohn's Disease
Interventions: DRUG: NNC 0142-0000-0002|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of In-phase Bilateral Exercise in People With Progressive Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Secondary Progressive
Interventions: BEHAVIORAL: In-phase Bilateral Exercise|BEHAVIORAL: Conservative exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Moderate to Severe Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Clear Cell Renal Cell Carcinoma Metastatic
Interventions: DRUG: Selenomethionine (SLM)|DRUG: Axitinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Low-Income Smokers in the Hospital Emergency Department
Status: COMPLETED
Conditions: Tobacco Use Cessation|Smoking Cessation|Smoking|Tobacco Use Disorder
Interventions: OTHER: Brief Intervention with NRT Initiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychological Profiles of Pediatric Obsessive Compulsive Disorder (OCD)
Status: TERMINATED
Conditions: Obsessive Compulsive Disorder (OCD)
Interventions: BEHAVIORAL: CBT for pediatric OCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?
Status: RECRUITING
Conditions: Cough|Airway Clearance Impairment|Neuromuscular Diseases
Interventions: OTHER: Learning the use of an in-exsufflation device with the guidance of a physiotherapist|OTHER: Using the coaching mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Follow up of Intravesical N-803 Plus BCG in BCG-Naive Non-Muscle Invasive Bladder Cancer (NMIBC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Muscle Invasive Bladder Cancer
Interventions: DRUG: N803 plus Bacillus Calmette-Guerin (BCG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Design and Evaluation of an Individualized Biodrug Tapering Strategy Based on Biodrug Dosage: the MONITORA Study
Status: NOT_YET_RECRUITING
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Clinical tapering strategy|DRUG: Step Wedge trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfer of Manualized Cognitive-Behavioral Therapy (CBT) for Social Phobia Into Clinical Practice
Status: UNKNOWN
Conditions: Social Phobia
Interventions: BEHAVIORAL: CBT-Manualized Intervention|BEHAVIORAL: CBT-Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Augmentation in Posterior Mandible Using Tunneling Technique With Amix of Autogenous Bone and Xenograft With and Without Collagen Membrane
Status: UNKNOWN
Conditions: Alveolar Ridge Augmentation
Interventions: PROCEDURE: tunneling technique bone augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate MEDI4736 in Combination With Tremelimumab
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Colorectal Cancer|Cervical Cancer|Renal Cell Carcinoma
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE
Status: NOT_YET_RECRUITING
Conditions: Rectum Cancer
Interventions: PROCEDURE: Plastic surgery of the pelvic floor and perineal wound with counter-displaced skin-subcutaneous fascial flaps after extralevatory abdominal-perineal extirpation of the rectum|PROCEDURE: Plastic surgery of the pelvic floor and perineal wound with local tissues|PROCEDURE: Plastic surgery of the pelvic floor and perineal wound with mesh endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Program in Patients With Shoulder Pain and Rotator Cuff Tear
Status: UNKNOWN
Conditions: Shoulder Pain|Rotator Cuff Injuries|Rehabilitation
Interventions: OTHER: Rotator Cuff Unloading Exercise Program|OTHER: Rotator Cuff Loading Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Mindfulness and Stress Resilience: A Mobile App Mindfulness Training Study
Status: COMPLETED
Conditions: Psychological Stress|Mindfulness
Interventions: BEHAVIORAL: Mindfulness Training|BEHAVIORAL: Mindful Attention Only Training|BEHAVIORAL: Analytic Thinking Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Administration Study of SND 919 Tablets in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Pramipexole 0.125 mg tablets|DRUG: Pramipexole 0.5 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Liver Care Trial
Status: RECRUITING
Conditions: Alcoholic Liver Disease|Alcohol Use Disorder|Alcohol Abuse|Alcoholism|Fibrosis, Liver|Alcohol-Related Disorders
Interventions: DIAGNOSTIC_TEST: Transient Elastography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Untreated Metastatic Squamous Neck Cancer With Occult Primary
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Intravenous Cannulation Using Three Different Techniques on Nursing Students
Status: COMPLETED
Conditions: Image|Knowledge, Attitudes, Practice
Interventions: OTHER: Near infrared light imaging|OTHER: Isometric exercise with stress ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
Status: RECRUITING
Conditions: Knee Injuries|Pain, Postoperative|Opioid Use
Interventions: DRUG: Norco 5Mg-325Mg Tablet|DRUG: Ibuprofen 600 mg|DRUG: Acetaminophen 325Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT