pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CKD-828 Primary Hypertension Trial(Dose-selection)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: S-Amlodipine, Telmisartan|DRUG: S-Amlodipine|DRUG: Telmisartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Tivanisiran to Treat Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Tivanisiran sodium ophthalmic solution|DRUG: Vehicle ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial of a Simulation-based Curriculum to Enhance Skills in Colonoscopy
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Curriculum Group|BEHAVIORAL: Self-directed learning group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: UCP (Ultrasound Cyclo Plasty) in the Treatment of Chinese Patients With Primary Open-angle Glaucoma
Status: UNKNOWN
Conditions: Glaucoma|Glaucoma, Primary Open Angle
Interventions: PROCEDURE: ultrasound cyclo plasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of MK-8245 in Participants With Type 2 Diabetes (MK-8245-012)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MK-8245|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Subjects and Mild Asthmatics to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways
Status: COMPLETED
Conditions: Healthy|Asthma
Interventions: DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Chronic Administration of Telmisartan as Monotherapy or in Combination With Hydrochlorothiazide or Other Antihypertensive Medications in Patients With Mild to Moderate Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studies Into Touch in Healthy Humans to Provide Sensory Feedback in Prostheses
Status: NOT_YET_RECRUITING
Conditions: Somatosensory Disorders|Amputation|Tactile Disorders|Aging|Prosthesis User
Interventions: DEVICE: Different surfaces to be touched|BEHAVIORAL: Emotional state change|DEVICE: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Epiction of the Genomic and Genetic Landscape Identifies CCL5 as a Protective Factor in Colorectal Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Colorectal Neuroendocrine Carcinomas (CRNEC); Genomic Landscape; Genetic Landscape; Prognosis; CCL5; PAX5
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Dose Intensification in Patients With Non-metastatic Ewing Sarcoma
Status: COMPLETED
Conditions: Ewing's Sarcoma
Interventions: DRUG: Standard treatment (as per protocol ISG SSG III)|DRUG: Intensified chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)
Status: COMPLETED
Conditions: Surgical Wound
Interventions: OTHER: Manual compression|DEVICE: Cardiva VASCADE™ Vascular Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Belzutifan (MK-6482) in Participants With Renal Impairment (MK-6482-021)
Status: COMPLETED
Conditions: End Stage Renal Disease|Renal Impairment
Interventions: DRUG: Belzutifan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Prospective Controlled Trial of Paraesophageal Hernia Repair With Small Intestinal Submucosa (SIS)
Status: COMPLETED
Conditions: Hernia|Paraesophageal Hernia
Interventions: DEVICE: hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hot Showers on Postpartum Fatigue, Mood and Comfort In Women Giving Vaginal Birth
Status: COMPLETED
Conditions: Fatigue|Comfort|Mood|Postpartum Care
Interventions: OTHER: Hot shower intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiovascular Health Promotion Among African-Americans by FAITH!
Status: COMPLETED
Conditions: Cardiovascular Diseases|Prevention|Physical Activity|Diet Modification|Diabetes|Hypertension|High Cholesterol|Pre Diabetes|Smoking Cessation|Obesity
Interventions: BEHAVIORAL: FAITH! App digital intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV
Status: WITHDRAWN
Conditions: RSV Infection|Stem Cell Transplant Complications|Lower Resp Tract Infection
Interventions: DRUG: RV521 oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Status: RECRUITING
Conditions: Hypertension|Cardiovascular Diseases
Interventions: DRUG: Ascorbic acid solution (American Regent Laboratories Inc.)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microencapsulated Fish Oil or Conjugated Linoleic Acid in Metabolic Syndrome
Status: COMPLETED
Conditions: Insulin Resistance|Oxidative Stress|Lipid Profile|Blood Pressure|Anthropometric Measure
Interventions: DIETARY_SUPPLEMENT: microencapsulated conjugated linoleic acid|DIETARY_SUPPLEMENT: microencapsulated fish oil|DIETARY_SUPPLEMENT: light fruit jam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Fentanyl as an Analgesic for Cystoscopic Procedures
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Fentanyl|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Effect of Serelaxin on High-sensitivity Cardiac Troponin I (Hs-cTnI) Release in Patients With Chronic Heart Failure
Status: TERMINATED
Conditions: Chronic Heart Failure
Interventions: DRUG: Serelaxin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: Relatlimab|BIOLOGICAL: Nivolumab|DRUG: BMS-986205|BIOLOGICAL: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the NRT CQSS2 System for Smoking Cessation in Treatment-Seeking Subjects
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: CQSS2|DRUG: NicoDerm CQ Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing the Wuqinxi on Patients With Pulmonary Arterial Hypertension
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Arterial Hypertension PAH
Interventions: OTHER: wu qinxi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utility of Tocolytic Therapy for Maintenance Tocolysis in the Management of Threatened Preterm Delivery
Status: WITHDRAWN
Conditions: Preterm Delivery.
Interventions: DRUG: progesterone 200 mg / day vaginally|DRUG: nifedipine (60 mg / day orally)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ketosteril on Sarcopenia in Patients With Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Disease|Sarcopenia
Interventions: COMBINATION_PRODUCT: low-protein diet + Ketosteril|DIETARY_SUPPLEMENT: low-protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Jia Wei Yang He Formula as a Plus Therapy in the Treatment of Persistent Asthma
Status: RECRUITING
Conditions: Bronchial Asthma
Interventions: DRUG: Jia Wei Yang He granule|DRUG: Jia Wei Yang He granule Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bezlotoxumab - in "Real Life" - During the First Episode of Clostridium Difficile Infection in Patients With High Risk of Recurrence.
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Bezlotoxumab Injection [Zinplava]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: oxaliplatin|DRUG: leucovorin calcium|DRUG: capecitabine|BIOLOGICAL: bevacizumab|DRUG: fluorouracil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vestibular Stimulation to Help Occasional Sleeplessness
Status: COMPLETED
Conditions: Insomnia|Sleeplessness|Transient Insomnia
Interventions: DEVICE: Electric stimulation of the Vestibular Nerve - "VirtuSom"|DEVICE: Electric stim of the Vestibular Nerve - "VirtuSom" - SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Venetoclax Tablet in Combination With Subcutaneous Low-Dose Cytarabine (LDAC) Injection to Assess Adverse Events in Adult Japanese Participants With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Venetoclax|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Lenalidomide (Revlimid®) in Patients With Multiple Myeloma and Impaired Renal Function
Status: COMPLETED
Conditions: Multiple Myeloma|Impaired Renal Function
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Axillary Reverse Mapping (ARM) Technique
Status: UNKNOWN
Conditions: Invasive Breast Cancer|Ductal Carcinoma in Situ of the Breast
Interventions: PROCEDURE: axillary reverse mapping (ARM)|PROCEDURE: Standard axillary surgery (SLNB or ALND)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cabozantinib in Metastatic Renal Cell Carcinoma (mRCC) With Brain Metastases
Status: RECRUITING
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Sunvozertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sintilimab Plus Bevacizumab and SIRT for Intermediate-advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Sin-Bev-SIRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Responsiveness in Patients With AECOPD Mechanical Ventilation by Inspiratory and Bronchial Dilation Testchronic Obstructive Pulmonary Disease
Status: UNKNOWN
Conditions: Lung Disease,Obstructive
Interventions: DRUG: Salbutamol Aerosol|DRUG: No drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorescein for Lymphatic Mapping and Sentinel Lymph Node (SLN) Biopsy in Patients With Stage I and II Malignant Melanoma
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Fluorescein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: (Cost)-Effectiveness of ABFT for Suicidal Youth.
Status: RECRUITING
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Attachment Based Family Therapy (ABFT) + Treatment As Usual (TAU)|BEHAVIORAL: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Lactobacillus Administered Vaginally in Women With Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: DRUG: LACTIN-V|DRUG: Placebo control substance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers
Status: COMPLETED
Conditions: Metformin|Organic Cation Transporter 2|Polymorphism,Single Nucleotide
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of RVT-501 in Adult and Adolescent Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: RVT-501 0.2% ointment|DRUG: RVT-501 0.5% ointment|OTHER: Vehicle ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutrition and Exercise Interventions in Reducing Androgen Deprivation Therapy-Induced Obese Frailty in Prostate Cancer Survivors
Status: RECRUITING
Conditions: Cancer Survivor|Obesity|Overweight|Prostate Adenocarcinoma|Stage A Prostate Cancer|Stage B Prostate Cancer|Stage C Prostate Cancer|Stage D Prostate Cancer|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage IIC Prostate Cancer|Stage III Prostate Cancer|Stage IIIA Prostate Cancer|Stage IIIB Prostate Cancer|Stage IIIC Prostate Cancer|Stage IV Prostate Cancer|Stage IVA Prostate Cancer|Stage IVB Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|OTHER: Educational Intervention|BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ACL Versus ALL + ACL Study
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injury|Ligament Rupture
Interventions: PROCEDURE: ACL plasty|PROCEDURE: ACL + ALL plasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bemiparin Randomized Trial on Bridging Oral Anticoagulants in Invasive Procedures (BERTA Study)
Status: TERMINATED
Conditions: Long-term Oral Anticoagulant Therapy
Interventions: DRUG: Bemiparina Sodica|DRUG: Heparina Cálcica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bosentan Effects in Inoperable Forms of Chronic Thromboembolic Pulmonary Hypertension
Status: COMPLETED
Conditions: Chronic Thromboembolic Pulmonary Hypertension
Interventions: DRUG: bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I
Status: COMPLETED
Conditions: Wound Surgical|Wound Heal|Oral Soft Tissue Conditions
Interventions: OTHER: Oral soft tissues biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study of Endostar Injection Concomitant With SOX Protocols to Treat Advanced Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Gimeracil and Oteracil Potassium Capsule|DRUG: Endostar injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation of Cognition in Older Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Sham Stimulation|DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mannitol-Induced Cough Challenge in Healthy Controls and Subjects With Mild Allergic Asthma
Status: COMPLETED
Conditions: Asthma|Cough
Interventions: OTHER: Mannitol|DRUG: Salbutamol 5mg/mL|OTHER: Sodium Chloride 0.9% Inhl 3Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study of RNS60 in Allergen-induced Bronchoconstriction
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: RNS60|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Liu-Zi-Jue Exercise Combined With Conventional Rehabilitation Treat Dysphagia in Post-stroke
Status: RECRUITING
Conditions: Stroke|Dysphagia
Interventions: COMBINATION_PRODUCT: Liu-Zi-Jue Exercise|OTHER: Basic treatment +Swallowing rehabilitation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)
Status: RECRUITING
Conditions: Non Hodgkin's Lymphoma|Large B-cell Lymphoma
Interventions: DRUG: SC262
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Clinical Trial Comparing Single Tooth Implant 3 Loading Protocols
Status: COMPLETED
Conditions: Dental Implant
Interventions: DEVICE: dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1|Islet Transplantation
Interventions: OTHER: Strict glucose control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Evolut FX Versus Sapien 3 Ultra Resilia.
Status: RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: Medtronic Evolut FX|DEVICE: Edwards Sapien 3 Ultra Resilia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of NPB-01 in Patients With Bullous Pemphigoid Unresponsive to Corticosteroids.
Status: COMPLETED
Conditions: Bullous Pemphigoid
Interventions: DRUG: NPB-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Ocular Surface Disease Assessment Between Monoprost and BAK-preserved Latanoprost
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: Monoprost|DRUG: Xalatan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Of Sunitinib Plus FOLFOX Versus Bevacizumab Plus FOLFOX In Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasms
Interventions: DRUG: sunitinib|DRUG: mFOLFOX6|DRUG: bevacizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Digital Clinic for Alcohol-associated Liver Disease and Alcohol Use Disorder (DALC)
Status: RECRUITING
Conditions: Alcohol Use Disorder|Liver Diseases
Interventions: OTHER: DALC Digital Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Chemoradiotherapy Followed By Surgery in Treating Patients With Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: irinotecan hydrochloride|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Bone and Body Comp: A Sub Study of the SECOND-LINE Study
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Lopinavir / ritonavir|DRUG: 2-3N(t)RTI|DRUG: raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Squamous Cell Head and Neck Carcinoma|Recurrent or Metastatic Disease
Interventions: BIOLOGICAL: cetuximab IV|OTHER: Biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switch From Combivir or Trizivir to Truvada - Mitochondrial Effects
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Truvada|DRUG: Combivir|DRUG: Trizivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Spot Versus Long Lesion Stenting as Best Treatment for Extensive Occlusive SFA Disease
Status: TERMINATED
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Short spot stenting|PROCEDURE: Long lesion stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOD-4023 Study in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MOD-4023 (long lasting hGH)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Alternating Current Stimulation (tACS) in Aphasia
Status: RECRUITING
Conditions: Aphasia|Stroke
Interventions: DEVICE: tACS 10-Hz|DEVICE: tACS 40-Hz|DEVICE: tACS sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Bioavailability When Preservative-free Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL) is Administered as an Intramuscular Manual Injection or as a Subcutaneous Injection Using an Auto-injector in Healthy Post-menopausal Women
Status: COMPLETED
Conditions: Comparing Bioavailability When Makena® is Administered in Healthy Post-menopausal Women
Interventions: DRUG: Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL)|DRUG: Makena® (Hydroxyprogesterone Caproate Injection, 250 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Nefopam Hydrochloride 30mg Tablets vs Acupan® 30mg Tablets in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nefopam Hydrochloride 30mg Tablets|DRUG: Acupan® 30mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and ASCT-related Symptom Burden Optimization of Tocilizumab in ASCT Following HD Melphalan Conditioning for Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OIF/β-TCP in Patients With Open Tibial Fractures in Need of Bone Grafting
Status: ACTIVE_NOT_RECRUITING
Conditions: Tibia Fracture
Interventions: DEVICE: OIF/β-TCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Renal Regional Oxygen Saturation Measured by Near-InfraRed Spectroscopy and Postoperative Renal Failure After Lung Transplantation Surgery: A Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Lung Transplant; Complications|Acute Kidney Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Yoga, Strength Training and Aerobic Exercise on Cognition in Adult Cancer Survivors
Status: COMPLETED
Conditions: Cancer|Cancer-related Problem/Condition|Exercise
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Stretching and Toning|BEHAVIORAL: Aerobic Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Vildagliptine and Glimepiride on Glucose Variability
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Glimepiride|DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacy Home Adherence Reporting and Monitoring Outcomes Study
Status: COMPLETED
Conditions: Diabetes|Hypertension|Hypercholesterolemia
Interventions: BEHAVIORAL: Pharmacist calls patient unless physician cancels call|BEHAVIORAL: Patient nonadherence information sent to physician|BEHAVIORAL: Pharmacist calls patient if physician requests call|BEHAVIORAL: Doctor receives information and may be allowed certain actions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing the Effectiveness of Phacoemulsification + ECP Laser and Phacoemulsification Alone for Glaucoma Patients
Status: UNKNOWN
Conditions: Glaucoma Open-Angle Primary|Cataract
Interventions: DEVICE: Phacoemulsification+ Endoscopic cyclophotocoagulation (ECP) laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anti-Estrogen Therapy for Hereditary Hemorrhagic Telangiectasia A Double-Blind Placebo-Controlled Clinical Trial
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia
Interventions: DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Absorption, Distribution, Metabolism, and Excretion of 14C-JNJ-42847922 After a Single Oral Dose of 40 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 14C-JNJ-42847922 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computed Tomography Screening for Early Lung Cancer, COPD and Cardiovascular Disease in Shanghai, China
Status: UNKNOWN
Conditions: Lung Neoplasms|Mass Screening|Chronic Obstructive Pulmonary Disease|Cardiovascular Disease
Interventions: OTHER: Low-dose CT screening with quantitative assessment and management of imaging biomarkers|OTHER: Low-dose CT screening with visual assessment and management of imaging biomarkers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin
Status: WITHDRAWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: ADI PEG20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of REOLYSIN® in Combination With Gemcitabine in Patients With Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: BIOLOGICAL: REOLYSIN|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Vein Thrombosis Treatment With the Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients Using a Strong CYP 3A4 Inducer
Status: COMPLETED
Conditions: Venous Thrombosis|Deep Vein Thrombosis
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of The Effect of Bupivacaine (Marcaine) in Reducing Early Post Tonsillectomy Pain
Status: UNKNOWN
Conditions: Tonsillectomy
Interventions: DRUG: Bupivacaine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety Study of 15-Valent Pneumococcal Conjugate Vaccine in 2-month-old and 3-month-old Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: 15-Valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 13-Valent Pneumococcal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Topical Dexmedetomidine on Intraocular Pressure
Status: COMPLETED
Conditions: Glaucoma|Intraocular Pressure
Interventions: DRUG: Dexmedetomidine|DRUG: Balanced salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Study of RETINA-AI Galaxy™, an Automated Diabetic Retinopathy Screening Device
Status: COMPLETED
Conditions: Diabetic Retinopathy|Diabetic Eye Problems|Diabetic Macular Edema
Interventions: PROCEDURE: Color Fundus Photography|DRUG: Mydriatics Agent|PROCEDURE: Optical Coherence Tomography (OCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety and Efficacy of Ustekinumab (CNTO 1275) in Participants With Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Ustekinumab 90 mg|DRUG: Ustekinumab 4.5 mg/kg|DRUG: Placebo SC|DRUG: Placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Follow-up of Patients With Chronic Inflammatory Rheumatisms (CIRs) Vaccinated Against COVID-19 Compared to Patients Refusing Vaccination
Status: COMPLETED
Conditions: Rheumatic Diseases|SARS-CoV Infection|COVID-19
Interventions: OTHER: Biological samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Benign or Malignant Rectal or Colon Tumors
Interventions: DEVICE: Robotic Assisted Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Personcentered Internet-based CBT Program for Stress, Anxiety and Depressive Symptoms in Patients With Cardiovascular Disease
Status: RECRUITING
Conditions: Cardiovascular Disease|Psychological Distress
Interventions: BEHAVIORAL: internet-based cognitive behavioral theraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of the Triptorelin 6-month Formulation in Paediatric Participants With Central Precocious Puberty.
Status: COMPLETED
Conditions: Central Precocious Puberty
Interventions: DRUG: Triptorelin Pamoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tobramycin in Bronchiectasis Colonized With Pseudmonas Aeruginosa
Status: UNKNOWN
Conditions: Bronchiectasis Adult|Pseudomonas Infections
Interventions: DRUG: Tobramycin Inhalant Product|OTHER: usual care|DRUG: Natural saline inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Alisertib + R-EPOCH for Treatment of Myc-Positive Aggressive B-cell Lymphomas
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma|Follicular Lymphoma|Burkitt Lymphoma
Interventions: DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral Suppression
Status: COMPLETED
Conditions: Antiretroviral Treatment Outcomes
Interventions: DRUG: Tenofovir, lamivudine and efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Confirmatory Study of TAU-284 in Pediatric Patients With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Bepotastine besilate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Steroid Delivery to the Frontal Sinus Opening With a Bioabsorbable Implant vs. a Bioabsorbable Nasal Dressing
Status: TERMINATED
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DEVICE: Bioabsorbable steroid releasing sinus implant|DEVICE: Bioabsorbable nasal dressing impregnated with steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of the Pigmentation in the Trabecular Meshwork After Two Years of Treatment With TRAVATAN 0.004% Ophthalmic Solution
Status: TERMINATED
Conditions: Open-angle Glaucoma
Interventions: PROCEDURE: Trabecular Meshwork Tissue Collection|DRUG: Travoprost 0.004% ophthalmic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioural Interventions to Improve Equity in Outpatient Access
Status: ENROLLING_BY_INVITATION
Conditions: Behavioural Science Interventions to Improve Health Equity
Interventions: BEHAVIORAL: Additional message with behavioural science-informed content and associated web pages|OTHER: Usual communication strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Same-Day PrEP Initiation and Sexual Health for Transgender Women
Status: COMPLETED
Conditions: HIV|PrEP|Transgender Women|Sexually Transmitted Diseases, Bacterial
Interventions: COMBINATION_PRODUCT: Integrated Next Steps Counseling with Real-Time Drug Level Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ACB + IPACK Block With or Without Local Infiltration in RA-TKA
Status: WITHDRAWN
Conditions: Knee Arthropathy
Interventions: OTHER: ACB + IPACK block with injection of local anesthetic|OTHER: ACB + IPACK block without injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral CDB-4124 vs. Placebo in Stage I-II Primary Breast Cancer
Status: UNKNOWN
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer
Interventions: DRUG: telapristone acetate|OTHER: placebo|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of GS-9411 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Cystic Fibrosis|Mucociliary Clearance|Airway Hydration
Interventions: DRUG: GS-9411|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self Expanding Nitinol Stent Versus Percutaneous Transluminal Arterial Angioplasty (PTA) With Optional Bailout Stenting in Case of PTA Failure in Patients With Symptomatic Critical Limb Ischemia or Severe Intermittent Claudication (EXPAND)
Status: COMPLETED
Conditions: Patients With Symptomatic Critical Limb Ischemia|Severe Intermittent Claudication
Interventions: DEVICE: Astron Pulsar Stent|DEVICE: PTA alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of E-PR-01 on Musculoskeletal Health in Physically Active Individuals
Status: COMPLETED
Conditions: Joint Pain
Interventions: DIETARY_SUPPLEMENT: E-PR-01 (Low dose)|DIETARY_SUPPLEMENT: E-PR-01 (High Dose)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Linezolid or Vancomycin Surgical Site Infection Prophylaxis
Status: NOT_YET_RECRUITING
Conditions: Antibiotic Prophylaxis|General Surgery
Interventions: DRUG: Vancomycin Injection|DRUG: Linezolid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Adenocarcinoma|Metastatic Small Intestinal Adenocarcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IV Small Intestinal Adenocarcinoma AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Biopsy|PROCEDURE: Fecal Microbiota Transplantation|DRUG: Fecal Microbiota Transplantation Capsule|DRUG: Metronidazole|DRUG: Neomycin|BIOLOGICAL: Nivolumab|BIOLOGICAL: Pembrolizumab|OTHER: Questionnaire Administration|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of PET With [89Zr]-Df-IAb2M and [111In]-Capromab Pendetide in the Detection of Prostate Cancer Pre-Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: [89Zr]Df-IAB2M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Quantified Analysis of Neuronal Recovery Using Myelin Imaging After Robot Assisted Upper Arm Training in Subacute Stroke Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: upper robot Robot assisted upper arm training(RAT)|BEHAVIORAL: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Self Monitoring of Capillary Blood Glucose at Home
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Conversation Maps Diabetes Education|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic|Acne
Interventions: PROCEDURE: Fat Grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Popliteal Sciatic Nerve Block and Adductor Canal Block
Status: COMPLETED
Conditions: Popliteal Sciatic Nerve Block|Adductor Canal Block
Interventions: PROCEDURE: Popliteal Sciatic Nerve Block|PROCEDURE: Adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Malignant Solid Tumor
Interventions: DRUG: Ifinatamab deruxtecan (I-DXd)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Inflammation in the Vitiligo and Other Inflammatory Skin Diseases: Psoriasis, Atopic Dermatitis and Alopecia Areata
Status: UNKNOWN
Conditions: Vitiligo|Psoriasis|Alopecia Areata|Atopic Dermatitis
Interventions: BIOLOGICAL: Blood samples|BIOLOGICAL: Skin biopsies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of LEO 90100 on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis VulgarisExtensive Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 90100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia
Status: TERMINATED
Conditions: COVID-19|Undefined
Interventions: BIOLOGICAL: AT-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Environmental Factors on the Efficacy of Non-surgical Periodontal Treatment. A Pre-post Quasi-experimental Study
Status: UNKNOWN
Conditions: Non Surgical Periodontal Treatment|Periodontitis|Periodontal Diseases
Interventions: PROCEDURE: Non-surgical periodontal treatment|OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Comparing Etoricoxib and Diclofenac Sodium in Post Hallux Valgus Surgery Pain
Status: WITHDRAWN
Conditions: Hallux Valgus|Postoperative Pain
Interventions: DRUG: etoricoxib|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Progressive Muscle Relaxation Training With Music Therapy on Sleep Quality and Trait Anger/Anger Expression Style of Patients at Community Mental Health Center
Status: COMPLETED
Conditions: Sleep|Anger|Psychiatric Disorder
Interventions: OTHER: Progressive Muscle Relaxation Training and Music Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE