pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Exercise Prior to Oesophagectomy
Status: UNKNOWN
Conditions: Postoperative Complications (Cardiopulmonary)|Oesophageal Adenocarcinoma
Interventions: BEHAVIORAL: Pre-operative Exercise Programme (my-PEP)|BEHAVIORAL: Home Exercise Programme (HEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Study of Intravenous Baclofen in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Safety and Pharmacokinetics of Intravenous Baclofen
Interventions: DRUG: Intravenous baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ASP1941 in Combination With Insulin in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: ipragliflozin|DRUG: Placebo|OTHER: Insulin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Conditions and Prevalence of Periodontopathogens in Smokers and Non-smokers After Periodontal Therapy
Status: UNKNOWN
Conditions: Periodontal Disease|Smoking
Interventions: PROCEDURE: Periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation as a New Approach for the Treatment of Nipple Traumas
Status: COMPLETED
Conditions: Injuries to the Nipple (Fissures and Cracks) Resulting Breastfeeding
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Lanolin for the Treatment of Nipple Pain Among Breastfeeding Women
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Lanolin|OTHER: Standard (usual) in-hospital and community postpartum care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Digital Colposcopy for Fluorescence Spectroscopy of TNC Using a Second Device
Status: WITHDRAWN
Conditions: Cervical Neoplasia
Interventions: PROCEDURE: Multi-spectral Digital Colposcopy (MDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants
Status: COMPLETED
Conditions: Allergic Rhinitis|Conjunctivitis
Interventions: DRUG: REGN5713|DRUG: REGN5714|DRUG: REGN5715|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Granulocyte Colony Stimulating Factor (G-CSF) After Salvage Chemotherapy in Refractory AML
Status: UNKNOWN
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Exergaming Exercises and Mediterranean Diet on Thyroid Cancer Patients Following Total Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid Cancer
Interventions: DEVICE: X-BOX kinetic360|DIETARY_SUPPLEMENT: mediterranean diet|DRUG: thyroid hormone replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis
Status: TERMINATED
Conditions: Neurofibromatosis and Malignant Peripheral Nerve Sheath Tumors
Interventions: DRUG: AL2846 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube
Status: COMPLETED
Conditions: Lung Diseases|Ultrasonography|Fiberoptic Bronchoscopy|One Lung Ventilation|Thoracic Surgery|Lung Collapse
Interventions: DIAGNOSTIC_TEST: Lung ultrasonography by experienced anaesthesiologist|DIAGNOSTIC_TEST: Fiberoptic bronchoscopy for double lumen tube's position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Preschool-Aged Refractive Measurements and Amblyopia Risks Using the 2WIN-S Portable Refractor With Vision Screening by Cycloplegic Refraction in Bangkok
Status: ACTIVE_NOT_RECRUITING
Conditions: 2WIN-S Portable Refractor
Interventions: DIAGNOSTIC_TEST: 2WIN-S portable refractor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess an Auto-injector Being Used to Treat a Migraine Attack
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: "Investigational"Auto-injector (sumatriptan succinate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi Occlusion of the Coronary Sinus as an Adjunct to PCI in STEMI Patients, FIH Clinical Study
Status: UNKNOWN
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: DEVICE: Booster Balloon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer（ALTER0303）
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: 400 µg Brimonidine Tartrate Implant|DRUG: 200 µg Brimonidine Tartrate Implant|OTHER: Sham (no implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interactive Web-based Program and CBT-coaching With Physiotherapy for Patients With Chronic Musculoskeletal Pain
Status: UNKNOWN
Conditions: Musculoskeletal Pain
Interventions: BEHAVIORAL: Web-prog, followed by CBT + PT|BEHAVIORAL: Base, followed by Web + CBT + PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of the Clinical and Biological Efficacity of NAAXIA SINE® in Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Keratoconjunctivitis, Vernal
Interventions: DRUG: N-acetyl-aspartyl-glutamate (NAAXIA Sine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refractive Consequences of Epiretinal Membrane Surgery
Status: COMPLETED
Conditions: Epiretinal Membrane
Interventions: PROCEDURE: Vitrectomy|PROCEDURE: Cataract surgery|PROCEDURE: Combined surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Hyperkinesis|Hypokinesia
Interventions: OTHER: Electrophysiological recordings
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of TJCS for Treatment of Moderate to Severe Dry Eye Syndromes
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: CYPORIN N EYE DROPS 0.05%(TJCS eye drop)|DRUG: Restasis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cholesterol Effects of Kori-tofu Proteins
Status: COMPLETED
Conditions: Lipid Metabolism Disorders
Interventions: OTHER: Kori tofu bread|OTHER: Whey protein bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Generalized Anxiety Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Cognitive Control Tasks and Script Driven Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Migraine Treatment in ED
Status: WITHDRAWN
Conditions: Migraine
Interventions: BEHAVIORAL: Relaxation Therapy|DRUG: Topiramate|DRUG: Standard of Care|DRUG: Abortive Medication (Naproxen and Sumatriptan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Stroke Patients ≤ 3 and ≤ 4.5 Hours of Symptom Onset by Fluid Attenuated Inversion Recovery (FLAIR) Imaging and Diffusion Weighted Imaging (DWI)
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of MEditerranean Diet, Inflammation and Microbiome After an Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: Microbiota analysis|OTHER: Immunological analysis|OTHER: Proteome analysis|OTHER: Metabolome analysis|OTHER: Clinical evaluation|OTHER: Diet evaluation|OTHER: MedDiet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pembrolizumab With Axitinib in Recurrent Endometrial Cancer
Status: WITHDRAWN
Conditions: Recurrent Endometrial Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicenter Doubleblind Randomized Study of NXL104/Ceftazidime + Metronidazole vs. Meropenem in Treatment of Complicated Intra-abdominal Infections
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infections
Interventions: DRUG: ceftazidime/NXL104 + metronidazole|DRUG: meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Different Doses of Acupuncture in Dysmenorrhea
Status: UNKNOWN
Conditions: Premenstrual Syndrome|Dysmenorrhea
Interventions: DRUG: Conventional gynecologic treatment|DEVICE: Low dose acupuncture|DEVICE: High dose acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Ventricular Assist Device Clinic
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Multidisciplinary team clinic and assessments (Cardiopulmonary exercise test, six-minute-walk-test, MoCA, Quality of Life questionnaires)|BEHAVIORAL: Caregiver Self-Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Status: ENROLLING_BY_INVITATION
Conditions: Orthodontic Tooth Movement|Intrusion of Tooth|Resorption, Root
Interventions: OTHER: Mini-screw|OTHER: Utility arch|OTHER: Nitinol reverse curve wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Feasibility Study to Evaluate the Safety and Short-term Effectiveness of Transcatheter Pulmonary Valve (TPV)
Status: COMPLETED
Conditions: Congenital Heart Defects|Cardiovascular Abnormalities|Pulmonary Valve Insufficiency|Pulmonary Valve Stenosis
Interventions: DEVICE: Transcatheter Pulmonary Valve (TPV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-Positive Primary Breast Cancer|Residual Invasive Breast Cancer
Interventions: DRUG: DS-8201a|DRUG: T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nociceptive Gain Processing After Physical Therapy in Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Surgical Group|OTHER: Physical Therapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-centre, Double-blind, Randomized, Vehicle-controlled Study of Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)
Status: COMPLETED
Conditions: Distal Subungual Onychomycosis
Interventions: DRUG: MOB015B|DRUG: MOB015B Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Using GSK233705 And Tiotropium In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK233705|DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiveness and Safety of Ramipril in the Treatment of Hypertension in Children and Adolescents
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: ramipril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy and Reproducibility of Virtually Guided Minimally Invasive Tooth Preparations Using Reverse Engineering
Status: UNKNOWN
Conditions: Marginal Adaptation of Fixed Dental Prosthesis
Interventions: DEVICE: Virtually guided minimally invasive preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zotarolimus-eluting Endeavor Sprint Stent in Uncertain DES Candidates (ZEUS) Study
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Bare metal stent implantation|DEVICE: zotarolimus eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Furcation treatment with PRF|PROCEDURE: Furcation Treatment with Allograft and GTR|DEVICE: allograft and guided tissue regeneration (GTR) membrane (DFDBM and Healiguide)|DEVICE: autologous platelet-rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: ISIS-GCGRRx- Dose Level 1|DRUG: ISIS-GCGRRx- Dose Level 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Phenytoin on the Pharmacokinetics of Nevirapine and the Development of Nevirapine Resistance
Status: COMPLETED
Conditions: HIV-infection|Pregnancy|Mother to Child Transmission
Interventions: DRUG: phenytoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel + Cetuximab + Concurrent Re-Irradiation (Intensity - Modulated Radiation Therapy, IMRT) for Patients With Locoregionally Recurrent Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: IMRT, cetuximab, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella-Zoster Virus (VZV) Vaccine in Adults With Hematologic Malignancies (HM) Receiving Treatment With Anti-Cluster of Differentiation (CD) 20 Monoclonal Antibodies (V212-013)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: V212
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: External Cold and Vibration Stimulation (Buzzy®) for Procedural Pain Management in Children Undergoing Needle-Related Procedures
Status: COMPLETED
Conditions: Child|Pain Due to Certain Specified Procedures
Interventions: DEVICE: Buzzy® device|DRUG: Maxilene® (Lidocaine liposomal 4%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Safety and Exploratory Efficacy of an Autologous Adipose-derived Cell Therapy Product for Treatment of Single Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: PSC-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Dopamine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Study to Evaluate the Effects of Sirukumab in Subjects With Severe Poorly Controlled Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Sirukumab|DRUG: Placebo|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Superficial Cervical Plexus Block on the Postoperative Quality of Recovery
Status: COMPLETED
Conditions: Cervical Disc Prolapse
Interventions: OTHER: Superficial cervical plexus block for experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oritavancin Versus IV Vancomycin for the Treatment of Participants With Acute Bacterial Skin and Skin Structure Infection (SOLO I)
Status: COMPLETED
Conditions: Wound Infection|Abscess|Systemic Inflammation|Cellulitis
Interventions: DRUG: Single-Dose IV Oritavancin Diphosphate|DRUG: IV Vancomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Reflux, Gastroesophageal
Interventions: DRUG: AH23844 (lavoltidine)|DRUG: NEXIUM (esomeprazole)|DRUG: ZANTAC (ranitidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleep IntervEntion as Symptom Treatment for ADHD
Status: COMPLETED
Conditions: ADHD|Sleep|Adolescents|CBT
Interventions: BEHAVIORAL: SIESTA|OTHER: Treatment as usual for ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Rhea Health Tone® as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia
Status: UNKNOWN
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Rhea Health Tone®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MSTT1041A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correction of the Unilateral Cleft Lip Nasal Deformity With Sliding Chondrocutaneous Flap and Autologous Cartilage Graft
Status: UNKNOWN
Conditions: Cleft Lip, Unilateral
Interventions: PROCEDURE: Unilateral cleft lip rhinoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Double-Blind Study on the Safety and Efficacy of Etanercept in Palmoplantar Pustulosis
Status: COMPLETED
Conditions: Palmoplantaris Pustulosis
Interventions: DRUG: Placebo comparator|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU
Status: RECRUITING
Conditions: Acute Respiratory Failure|Intubation|Intubation; Difficult or Failed|Videolaryngoscopy|Intubation Complication
Interventions: DEVICE: Hyperangulated blade videolaryngoscope|DEVICE: Macintosh blade videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy
Status: NOT_YET_RECRUITING
Conditions: Proliferative Vitreoretinopathy|Proliferative Vitreo-Retinopathy|Rhegmatogenous Retinal Detachment
Interventions: DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of R21 +/- ChAd63/MVA ME-TRAP
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: R21 with Matrix-M1|BIOLOGICAL: ChAd63 ME-TRAP|BIOLOGICAL: MVA ME-TRAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Video Editing Training for Novice Trainees in Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Gallstone; Colic
Interventions: PROCEDURE: video editing training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Post Surgical Pain in Arthroscopic Shoulder
Status: COMPLETED
Conditions: Total Shoulder Arthroplasty
Interventions: PROCEDURE: shoulder periarticular injection, suprascapular and axillary nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Episode|Depressive Disorder, Major
Interventions: DEVICE: active rTMS over DLPFC|DEVICE: Add-on active rTMS over DLPFC|DEVICE: Add-on active rTMS over LPC|DEVICE: Add-on sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association of Genetic Polymorphisms With Atrial Fibrosis and Thrombogenic Substrate in Patients With Non-valvular Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Thrombosis|Stroke|Genetic Predisposition|Heart Diseases
Interventions: DIAGNOSTIC_TEST: Biomarkers, Cardiac Magnetic Resonance Imaging, Echocardiography, Flow Mediated Dilatation, Genetic Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2 Study of KHK4577
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: KHK4577|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consequences of Parenteral Nutrition Photoprotection on Oxidant Related Diseases Among Extremely Low Birth Weight Infants
Status: COMPLETED
Conditions: Infant, Premature
Interventions: DEVICE: photoprotected bags, tubing, syringes|DEVICE: standard tubing and bags
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Complete Resection of Barrett's Esophagus Harboring Neoplasia With Endoscopic Submucosal Dissection.
Status: RECRUITING
Conditions: Barretts Esophagus With Dysplasia
Interventions: PROCEDURE: ESD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Advanced Soft Tissue Sarcoma
Interventions: DRUG: TRC105 and Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Comparing Delandistrogene Moxeparvovec With Standard of Care in Participants With Duchenne Muscular Dystrophy
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: delandistrogene moxeparvovec|DRUG: Standard of Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Atezolizumab in Unresectable or Advaced Malignant Pleural Mesothelioma
Status: WITHDRAWN
Conditions: Malignant Pleural Mesothelioma, Advanced|Malignant Pleural Mesothelioma, Unresectable
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mulberry Leaves on Glycemic Control in Patients With Obesity and Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Mulberry leaves powder|BEHAVIORAL: Diet control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide, Cyclophosphamide and Dexamethasone for Recurrent/Refractory Adult Langerhans Cell Histiocytosis
Status: UNKNOWN
Conditions: Langerhans Cell Histiocytosis
Interventions: DRUG: thalidomide combined with dexamethasone and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Method of Rehabilitation for Patients After Myocardial Revascularization
Status: ACTIVE_NOT_RECRUITING
Conditions: Rehabilitation|Low Back Pain|Revascularization
Interventions: OTHER: Rehabilitation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Botulinum Toxin Pyloroplasty to Reduce Postoperative Nausea and Vomiting After Sleeve Gastrectomy
Status: COMPLETED
Conditions: Bariatric Surgery|Postoperative Nausea and Vomiting
Interventions: DRUG: Botulinum toxin pyloroplasty|DRUG: Normal saline pyloric injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Determine the Safety, Pharmacokinetics, and Efficacy of OPC-108459 Administered as a Single Intravenous Dose to Patients With Paroxysmal or Persistent Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: OPC-108459|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC)
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity|Cardiovascular Diseases|Metabolic Disease|Diabete Type 2|Sleep Apnea, Obstructive|NAFLD|NASH
Interventions: BEHAVIORAL: Nutritional Psycho-Behavioral Reeducation Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polyethylene Glycol to Improve Sensation Following Digital Nerve Laceration
Status: WITHDRAWN
Conditions: Peripheral Nerve Injury|Nerve Injury
Interventions: DRUG: Polyethylene Glycol 3350|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sexual Therapy and Rehabilitation After Treatment for Ovarian Cancer (START-OC): A Pilot Intervention
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: BEHAVIORAL: Group Session|BEHAVIORAL: Telephone Coaching Session|BEHAVIORAL: Webinar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MediBeat - HeartBeat Observation Trial
Status: COMPLETED
Conditions: Low Blood Pressure|Blood Pressure|High Blood Pressure|Hypertension|Hypotension
Interventions: DEVICE: Contec CMS50EW|DEVICE: Sphygmomanometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Pentoxyphilline and Tocopherol on the Fibrosis in Patients With Chronic Hepatitis C
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Liver Fibrosis
Interventions: DRUG: pentoxyphilline|DRUG: tocopherol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Sacituzumab Govitecan in People With Mesothelioma
Status: RECRUITING
Conditions: Mesothelioma|Mesotheliomas Pleural|Mesothelioma; Pleura
Interventions: DRUG: Sacituzumab govitecan-hziy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: RADIATION: Radiation|RADIATION: brachytherapy|DRUG: Cisplatin|OTHER: Hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon α2a Versus Cyclosporine for Refractory Behçet's Disease Uveitis
Status: COMPLETED
Conditions: Behçet Disease|Uveitis
Interventions: DRUG: Interferon Alfa-2A|DRUG: Cyclosporine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Videoconferencing on Teaching Parent Training Skills to Parents of Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: parent training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nursing Care of Bipolar Patients With Sleeping Disorders Using Luminotherapy and /or Psychoeducation Program (BIPLUMINO)
Status: RECRUITING
Conditions: Bipolar Disorder
Interventions: OTHER: Luminotherapy and /or Psychoeducation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis
Interventions: OTHER: Placebo|DRUG: Nipocalimab|DRUG: Standard-of-care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Acetyl L-Carnitine in COVID-19 Patients With Mild-to-Moderate Disease
Status: UNKNOWN
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Acetyl L-Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restoration of Reaching and Grasping Function in Individuals With Spinal Cord Injury Using MyndMove® Neuromodulation Therapy
Status: COMPLETED
Conditions: Spinal Cord Injuries|Trauma, Nervous System
Interventions: DEVICE: MyndMove®|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REpositionable Percutaneous Replacement of NatIve StEnotic Aortic Valve Through Implantation of LOTUS EDGE Valve System
Status: TERMINATED
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: LOTUS Edge Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopy After Pretreatment With Misoprostol and Estradiol Trial
Status: COMPLETED
Conditions: Cervical Ripening
Interventions: DRUG: Misoprostol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of REGN88(SAR153191) in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: REGN88|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Histopathologic Changes in Dental Follicle Associated With Radiographically Normal Impacted Lower Third Molars
Status: COMPLETED
Conditions: Follicle Cyst|Teeth, Impacted|Pathology
Interventions: PROCEDURE: The follicular tissues were also excised after tooth extraction.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: External-Beam Partial-Breast Irradiation for Early Breast Cancer 40 Gy QD Over 2 Weeks
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: External Beam Partial-Breast Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ACT-1014-6470 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Research of Metabolomics on COPD
Status: COMPLETED
Conditions: Metabolomics|Omega 6|Omega 3|COPD
Interventions: DIAGNOSTIC_TEST: Lung function test was performed on the subjects with Jaeger lung function instrument of Germany.|DIAGNOSTIC_TEST: Agilent 1290 Infinity LC system (UHPLC, Santa Clara CA) was used for Targeted metabolite detection.|DIAGNOSTIC_TEST: Routine blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-Label Study To Assess The Pharmacokinetics, Safety And Toleration Of Vfend®; Following Multiple Dosing With Vfend
Status: TERMINATED
Conditions: Kidney Failure
Interventions: DRUG: Vfend®; I.V.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Obstetric Life Support, a Curriculum to Effectively Resuscitate Pregnant Patients Experiencing Cardiac Arrest.
Status: UNKNOWN
Conditions: Cardiac Arrest|Pregnancy Related
Interventions: OTHER: Electronic curriculum and instructor-led course, then placebo|OTHER: Placebo, then electronic curriculum and instructor-led course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Axillary Lymph Node Treatment Guided by Naocarbon Tracing After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: SLNB|PROCEDURE: pALND|PROCEDURE: ALND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Pilot Study of 18F-Sodium Fluoride (Na18F) Whole Body Positron Emission Tomography (PET) Scans for Imaging Bone
Status: TERMINATED
Conditions: Bone Scan
Interventions: OTHER: 18F-Sodium Fluoride (Na18F)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing Test to Aczone 5% and Both to a Placebo Control in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Test.|DRUG: Aczone Gel 5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SILibinin in NSCLC and BC Patients With Single Brain METastasis (SILMET)
Status: RECRUITING
Conditions: Brain Metastases, Adult|Non Small Cell Lung Cancer|Breast Cancer
Interventions: DIETARY_SUPPLEMENT: Silibinin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Sentinel Node Policy in Early Stage Endometrial Carcinomas at Intermediate and High Risk of Recurrence.
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Carcinoma
Interventions: DRUG: Pre-operative SN mapping with radionucleide|DRUG: Intra-operative SN mapping with patent V blue dye|DRUG: Intra-operative SN mapping with indocyanin green|PROCEDURE: Full bilateral laparoscopic lymphadenectomy and Hysterectomy|PROCEDURE: Current initial staging protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine and Radiation Therapy With or Without Panitumumab in Treating Patients With Advanced Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: capecitabine|PROCEDURE: therapeutic conventional surgery|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Nurse Home Visitation to Prevent Intimate Partner Violence
Status: COMPLETED
Conditions: Violence|Emotional Abuse|Pregnancy|Parenting
Interventions: BEHAVIORAL: Enhanced NFP (NFP+)|BEHAVIORAL: NFP as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Bermekimab (JNJ-77474462) in the Treatment of Participants With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Placebo|DRUG: Bermekimab|DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Community Engagement Using M-Mama Champions
Status: NOT_YET_RECRUITING
Conditions: Obstetric Complication|Woman's Role
Interventions: OTHER: Community engagement using M-MAMA Champions to improve awareness on obstetric danger signs, bith preparedness and complication readiness among pregnant women
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Messenger Ribonucleic Acid (mRNA) Transfected Dendritic Cell Vaccination in High Risk Uveal Melanoma Patients
Status: TERMINATED
Conditions: Uveal Melanoma
Interventions: BIOLOGICAL: autologous dendritic cells electroporated with mRNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery
Status: COMPLETED
Conditions: Arthroplasty, Hip Replacement|Infection, Postoperative Wound
Interventions: DRUG: DuraPrep|DRUG: ChloraPrep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: BEHAVIORAL: CPAP + Peer Support|BEHAVIORAL: CPAP + Individual Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Texting Messaging to Improve the Hospital-to-community Transition Period in Cardiovascular Disease Patients
Status: COMPLETED
Conditions: Cardiovascular Disease|Acute Coronary Syndrome
Interventions: BEHAVIORAL: Txt2Prevent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Visual and Audio Stimulus Offered to Father-to-be
Status: RECRUITING
Conditions: Ultrasonography Prenatal
Interventions: OTHER: USE OF MOBILE ULTRASOUND|OTHER: ultrasound image taken from the internet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vessel Wall Imaging for Diagnosis and Monitoring of Central Nervous System (CNS) Vasculitis
Status: COMPLETED
Conditions: Vasculitis, CNS|Vasculitis, Cerebral
Interventions: DIAGNOSTIC_TEST: MRI, including intracranial vessel wall imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lorlatinib Combinations in Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer|Anaplastic Lymphoma Kinase Gene Translocation|ROS1 Rearrangement|Relapsed Cancer|MET Amplification|Resistant Cancer|NSCLC
Interventions: DRUG: Lorlatinib|DRUG: Crizotinib|DRUG: Binimetinib|DRUG: TNO155
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Retained and Non-retained Urinary Catheter in Total Knee Arthorplasty With Epidural Anesthesia
Status: COMPLETED
Conditions: Postoperative Urinary Retention|Urinary Tract Infections|Epidural Anesthesia
Interventions: PROCEDURE: Total knee arthroplasty|PROCEDURE: Urinary Catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single-Dose Phase 1 Study of TAK-792
Status: COMPLETED
Conditions: Healthy Male Adults Participants
Interventions: DRUG: TAK-792 30 mg|DRUG: TAK-792 30 mg placebo|DRUG: TAK-792 100 mg|DRUG: TAK-792 100 mg placebo|DRUG: TAK-792 250 mg|DRUG: TAK-792 250 mg placebo|DRUG: TAK-792 500 mg|DRUG: TAK-792 500 mg placebo|DRUG: TAK-792 750 mg|DRUG: TAK-792 750 mg placebo|DRUG: TAK-792 1250 mg|DRUG: TAK-792 1250 mg placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C-Protein in Fatigue and Aging
Status: RECRUITING
Conditions: Aging|Muscle Atrophy or Weakness|Sarcopenia in Elderly|Sarcopenia
Interventions: BEHAVIORAL: Fatiguing Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE