pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: F-18 TFB-PET Studies in Cancer Patients Undergoing NIS-containing Viral Therapies
Status: COMPLETED
Conditions: Myeloma Before MV-NIS Treatment|Endometrial Cancer Before VSV-hINF-NIS Treatment
Interventions: COMBINATION_PRODUCT: 18F-TFB-PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tandem Auto Stem Cell Transplant With Melphalan Followed by Melphalan and Bortezomib in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Auto Stem Cell Transplant
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This is a Phase 1 Study of MH048 in Patients With Selected Relapsed/Refractory B-cell Malignancies
Status: UNKNOWN
Conditions: Relapsed/Refractory B-cell Malignancies
Interventions: DRUG: MH048
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study
Status: COMPLETED
Conditions: Healthy|Substance-related Disorder|Mood Disorder
Interventions: DRUG: Methylphenidate|DRUG: Modafinil|DRUG: MDMA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Administration of Olaparib With Cisplatin or With Durvalumab or Alone or no Tratment in Patients Who Are Candidates for Surgery of Carcinoma of the Head and Neck.
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Olaparib|DRUG: Cisplatin|DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
Status: ENROLLING_BY_INVITATION
Conditions: Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
Interventions: DRUG: MDMA, LSD, psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cancer Pain Rehabilitation Program to Reduce Pain Related Distress, and Reliance of Pain Medication Through Multimodal Nonpharmacological Solutions
Status: COMPLETED
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Behavioral, Psychological or Informational Intervention|OTHER: Educational Intervention|PROCEDURE: Manipulative and Body-Based Intervention Procedure|BEHAVIORAL: Occupational Therapy|OTHER: Physical Activity|PROCEDURE: Physical Therapy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emotion Recognition Training in Antisocial Violent Offenders With Psychopathic Traits
Status: UNKNOWN
Conditions: Psychopathy|Violent Aggressive Behavior|Emotional Problem
Interventions: BEHAVIORAL: SEE Training|BEHAVIORAL: GAZE Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Nivolumab Alone, Or In Combination With Vinblastin In Patients With Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Coexisting Medical Conditions
Interventions: DRUG: Nivolumab|DRUG: Vinblastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restrictive Versus Liberal Red Cell Transfusion Strategy in Orthopedic-Oncology Patients Undergoing Surgery - a Randomized Controlled Study
Status: UNKNOWN
Conditions: Red Blood Cells Transfusion.
Interventions: OTHER: Red blood cells transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Blood Pressure Monitor With AFib Screening Feature
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: OMRON blood pressure monitor with AFib screening feature|DEVICE: Microlife WatchBP Home A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety and Tolerability of Lenvatinib in Participants With Advanced or Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Lenvatinib|DRUG: Sorafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Receiving Sipuleucel-T
Status: COMPLETED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Malignant Neoplasm in the Bone|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic Differentiation of Tachycardia Episodes Using Tissue Perfusion
Status: TERMINATED
Conditions: Arrhythmias, Cardiac
Interventions: PROCEDURE: High rate atrial and vetricular stimulation|PROCEDURE: Ventricular Tachycardia induction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma
Status: RECRUITING
Conditions: Cutaneous Angiosarcoma
Interventions: DRUG: Paclitaxel|RADIATION: Radiation therapy|PROCEDURE: Research blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Sustainable Return to Work Among Employees on Sick Leave Due to a Mental Health Condition: Evaluation of the HealthyMinds Online Group Intervention
Status: RECRUITING
Conditions: Depression Anxiety Disorder|Adjustment Disorders|Adjustment Disorder With Anxious Mood|Adjustment Disorder With Depressed Mood
Interventions: BEHAVIORAL: Healthy Minds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hormonal Contraception and Vaginal Health
Status: COMPLETED
Conditions: Contraceptive Usage|Vaginal Epithelial Disruption
Interventions: DRUG: Desogen (ethinyl estradiol and desogestrel)|DRUG: NuvaRing (ethinyl estradiol and etonogestrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of a Brief Intervention to Improve Engagement in Early Intervention Services for Psychosis
Status: NOT_YET_RECRUITING
Conditions: Psychotic Disorders|Psychiatric Hospitalization|Engagement, Patient
Interventions: OTHER: Just Do You
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Dermatological Assessment of Topical Use Product Through Dressings Predictive Studies for Evaluation of Photoirritation and Dermal Photosensitivity
Status: COMPLETED
Conditions: Skin Irritability|Skin Sensitization
Interventions: DEVICE: KL029 Intimate Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Safety Study of the PrePex Device for Non-Surgical Adult Male Circumcision During Phased in National Implementation in an Effort to Prevent the Spread of HIV
Status: COMPLETED
Conditions: Male Circumcision
Interventions: DEVICE: PrePex™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase Ib and Phase II Studies of MK-3475 in Combination + for Renal Cell Carcinoma:
Status: COMPLETED
Conditions: Clear Cell Renal Carcinoma
Interventions: DRUG: MK-3475|DRUG: Bevacizumab|DRUG: MK-3475|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Clonazepam on REM Sleep Behavior Disorder in Patients With Parkinsonism
Status: COMPLETED
Conditions: REM Sleep Behavior Disorder
Interventions: DRUG: Clonazepam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Possible Improvement in Tinnitus Severity After 28 Days Dosing of the Study Drug AUT00063 Compared to Placebo
Status: COMPLETED
Conditions: Tinnitus, Subjective
Interventions: DRUG: AUT00063|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modafinil vs Placebo for the Treatment of Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SK-1401 (rhGM-CSF Agent for Inhalation) GM-CSF Inhalation Pharmacokinetic Study
Status: COMPLETED
Conditions: Pulmonary Alveolar Proteinosis, Autoimmune
Interventions: DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zibotentan Better Renal Scleroderma Outcome Study
Status: COMPLETED
Conditions: Scleroderma|Scleroderma Renal Crisis|Chronic Kidney Disease
Interventions: DRUG: Zibotentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CivaSheet With Radical Prostatectomy & Adjuvant External Beam Radiation
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: RADIATION: Civasheet 60 Gy|RADIATION: Civasheet 75 Gy|RADIATION: Adjuvant external beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modification of Asthma With Soy Isoflavone
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Soy Isoflavone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Clinical Analysis of HIPEC for T4 Colorectal Cancer After Surgery
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: Surgery and HIPEC with Lobaplatin|PROCEDURE: Surgery without HIPEC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Pemetrexed With or Without PF-3512676 in Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: pemetrexed|DRUG: pemetrexed + PF-3512676
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Diaphragmatic Breathing With and Without Aerobic Exercise on Stress, Fatigue and Sleep Quality
Status: COMPLETED
Conditions: Stress|Fatigue|Sleep
Interventions: OTHER: Diaphragmatic breathing|OTHER: Aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Toripalimab Plus TPF Chemotherapy and Radiotherapy for LA-HPSCC
Status: NOT_YET_RECRUITING
Conditions: Hypopharyngeal Neoplasm Malignant Primary
Interventions: DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InFocus France Epidemiological Study of Health Burden in Major Hypertriglyceridemia
Status: COMPLETED
Conditions: Familial Chylomicronemia Syndrome|Multifactorial Chylomicronemia Syndrome
Interventions: OTHER: observational : questionnaries for assessment of health burden
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever
Status: COMPLETED
Conditions: Typhoid|Paratyphoid Fever
Interventions: BIOLOGICAL: Typhoid Vi vaccine|BIOLOGICAL: Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of OSTENIL PLUS (Hyaluronic Acid) Versus SYNVISC-ONE in Patients With Tibiofemoral Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: OSTENIL PLUS|DEVICE: SYNVISC-ONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Web-based Smoking Cessation Program for Tribal College Students
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: OTHER: Internet-All Nations Breath of Life (I-ANBL)|OTHER: Honoring the Gift of Heart Health|DRUG: Nicotine gum, Patch, or Lozenge or Zyban® or Chantix®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Pain Reduction by Peri-arthroscopic PRP Application in Knee Degeneration
Status: COMPLETED
Conditions: Knee Osteoarthritis|Cartilage Damage|Meniscal Tear
Interventions: BIOLOGICAL: Platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Endoscopy Screening on Esophageal Cancer in China (ESECC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Dysplasia
Interventions: PROCEDURE: Endoscopic Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Electrode Site Reaction
Interventions: DEVICE: RM Electrode|DEVICE: ERG Jet Electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Virtual Reality Glasse on Pain and Anxiety During Episiotomy Repair
Status: COMPLETED
Conditions: Anxiety|Pain|Episiotomy Wound|Midwifery
Interventions: OTHER: VR group|OTHER: Skin to skin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sodium Excretion of LCZ696 in Patients With Hypertension; Heart Failure and Healthy Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: LCZ696|DRUG: Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accelerated iTBS for Depression and Suicidality
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder|Suicide
Interventions: DEVICE: Accelerated Intermittent Theta Burst (aiTBS)|DEVICE: Electroconvulsive therapy (ECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of mDOT for Immunosuppressant Adherence in Adult Kidney Transplant Recipients
Status: WITHDRAWN
Conditions: Medication Adherence|Transplant; Kidney
Interventions: OTHER: mHealth Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ESWT for Shoulder Pain in Patients With Brain Damage
Status: UNKNOWN
Conditions: Brain Damage, Hypoxic|Stroke|Brain Tumor|ICH
Interventions: DEVICE: Extracorporeal shockwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Budesonide Versus Mesalazine Versus Placebo in Lymphocytic Colitis
Status: COMPLETED
Conditions: Lymphocytic Colitis
Interventions: DRUG: Budesonide|DRUG: Mesalamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Cervical Traction Versus Snag to Improve Pain and Quality of Life in Cervical Radiculopathy
Status: RECRUITING
Conditions: Quality of Life|Cervical Radiculopathy
Interventions: DIAGNOSTIC_TEST: Cervical Traction|DIAGNOSTIC_TEST: Snag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC
Status: COMPLETED
Conditions: Oropharynx Cancer|Oral Cancer|Hypopharynx Cancer|Larynx Cancer
Interventions: PROCEDURE: Radiotherapy 62-64 Gy in 5 W (31-32 f. of 2 Gy BID)|PROCEDURE: Radiotherapy 62-64 Gy in 22-23 D (31-32 f of 2 Gy BID)|DRUG: CDDP, 5 Fu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Electrical Neuromodulation of the Globus Pallidus Intern in Parkinson's Disease by the Directional Electrode CARTESIA™
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Classical ring stimulation|DEVICE: Stimulation in directional mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nab-Paclitaxel and Bevacizumab Followed By Bevacizumab and Erlotinib in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Triple-negative Breast Cancer
Interventions: DRUG: paclitaxel albumin-stabilized nanoparticle formulation|BIOLOGICAL: bevacizumab|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Japanese Women Going Through Menopause
Status: RECRUITING
Conditions: Hot Flashes
Interventions: DRUG: Fezolinetant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission
Status: RECRUITING
Conditions: Non-radiographic Axial Spondyloarthritis
Interventions: DRUG: Secukinumab|DRUG: Placebo|DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rebamipide AND Sjögren Syndrome
Status: UNKNOWN
Conditions: Improving Symptoms of Dry Mouth in Sjőgren's Syndrome
Interventions: DRUG: Rebamipide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Control Effect of BSG and Underlying Gut - Related Mechanism in Singapore Adults With Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome|Diabetes
Interventions: DIETARY_SUPPLEMENT: control biscuits|DIETARY_SUPPLEMENT: autoclaved BSG-containing biscuits|DIETARY_SUPPLEMENT: bio-transformed BSG-containing biscuits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metformin in Diabetic Patients Undergoing Coronary Angiography
Status: UNKNOWN
Conditions: Diabetes Mellitus|Coronary Artery Disease|Lactic Acidosis With Diabetes Mellitus|Contrast-induced Nephropathy|Metformin Associated Lactic Acidosis
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Compare PT007 to Placebo MDI and Open-Label Proventil® HFA in Adult and Adolescent Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AS MDI 90 μg|DRUG: AS MDI 180 µg|OTHER: Placebo MDI|DRUG: Proventil 90 μg|DRUG: Proventil 180 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of Topical Recombinant Thrombin in Surgical Hemostasis
Status: COMPLETED
Conditions: Spinal Surgery|Vascular Surgery
Interventions: BIOLOGICAL: rThrombin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Case-control Study in Patients With PAA
Status: RECRUITING
Conditions: Popliteal Artery Aneurysm|Peripheral Arterial Disease|Quality of Life
Interventions: OTHER: Bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Responses to Rabies Vaccine in Adults With or Without Antibiotics
Status: COMPLETED
Conditions: Rabies Human
Interventions: BIOLOGICAL: Rabies Vaccine|DRUG: Metronidazole|DRUG: Vancomycin|DRUG: Neomycin Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Oxytocin Alter Tolerance to or Motivation for Alcohol
Status: TERMINATED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Intranasal oxytocin|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: New Treatment for Patients With Temporal Hollowing After Lateral Wall Decompression
Status: COMPLETED
Conditions: Thyroid-Associated Ophthalmopathy
Interventions: PROCEDURE: Autologous fat injection|PROCEDURE: Hyaluronic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2 Different Positional Therapies for Positional Obstructive Sleep Apnea Syndrome
Status: TERMINATED
Conditions: Positional Obstructive Sleep Apnea
Interventions: DEVICE: Consecutive trial of two different devices for the treatment of positional sleep apnoea, for 3 nights with each device (positional pillow and vibrating belt).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selection of Allogeneic Hematopoietic Cell Donors Based on KIR and HLA Genotypes
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: GENETIC: KIR genotyping|GENETIC: HLA genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Amlodipine and Aliskiren in Diabetic Hypertensive Patient With Blood Pressure Not Controlled by Losartan
Status: WITHDRAWN
Conditions: Hypertension|Diabetes Mellitus
Interventions: DRUG: Aliskiren|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evidence of Neuroplasticity After Performing a Cognitive Task in Idiopathic Parkinson's Disease Patients
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Playing a computer game simulating a car race
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma or Ocular Hypertension
Interventions: DRUG: Netarsudil Ophthalmic Solution 0.02%|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Depressive Symptoms|Depressive Disorder, Major|Depressive Episode|Depression Severe
Interventions: DRUG: TNX-601 ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mecapegfilgrastim(PEG-G-CSF) for Prophylaxis of Chemotherapy-induced Neutropenia in Patients With Lymphoma
Status: UNKNOWN
Conditions: Chemotherapy-induced Neutropenia|Lymphoma
Interventions: DRUG: Pegylated rhG-CSF|DRUG: rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
Status: TERMINATED
Conditions: Fatigue|Sleep Deprivation|Depression
Interventions: BEHAVIORAL: Protected time and Dedicated time
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women
Status: COMPLETED
Conditions: Alopecia
Interventions: OTHER: Platelet Rich Plasma|DRUG: Minoxidil Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Efficacy Study of TPI 287 to Treat Primary Refractory or Early Relapsed Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: DRUG: TPI 287|DRUG: Temozolomide|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coordination of Care Between Pediatricians and Women Infants & Children Nutritionists
Status: COMPLETED
Conditions: Childhood Obesity
Interventions: BEHAVIORAL: Early healthy lifestyles|BEHAVIORAL: Responsive parenting curriculum|BEHAVIORAL: Data sharing/coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Full Pulpotomy Procedure of Permanent Molar Teeth of Adults Using Calcium Silicate-based Sealer Material
Status: NOT_YET_RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Calcium silicate-based sealer full Pulpotomy|PROCEDURE: Calcium silicate-based premixed putty full Pulpotomy|PROCEDURE: Full Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study In Pediatric Subjects With Asthma Using ADVAIR HFA, ADVAIR HFA With Spacer, And ADVAIR DISKUS
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: ADVAIR HFA|DRUG: ADVAIR DISKUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Balloon and Postoperative Estrogen Therapy in the Prevention of Adhesion Reformation After Hysteroscopic Adhesiolysis
Status: UNKNOWN
Conditions: Uterine Septum
Interventions: DEVICE: Foley balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Massage and Hydrotherapy to Improve Well-being and Pain Perception in Endometriosis Patients
Status: RECRUITING
Conditions: Endometriosis|Chronic Pelvic Pain Syndrome
Interventions: OTHER: Hydrotherapy + massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"
Status: NOT_YET_RECRUITING
Conditions: To Determine the Optimal Doses of Adrenaline in Preventing Blood Loos in Participants Undergoing Supraclavicular Flap Surgery
Interventions: DRUG: Epinephrine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigating HD-tDCS in Improving Word Finding and Memory Retrieval in Individuals With MCI
Status: WITHDRAWN
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Active frontal|DEVICE: Active parietal|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Brain Involvement
Interventions: DRUG: DM-CHOC-PEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Pediatric Liver Transplantation Without Steroids
Status: TERMINATED
Conditions: Evidence of Liver Transplantation
Interventions: DRUG: methyl prednisolone, hydrocortisone, prednisolone|OTHER: No steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Kidney Cancer|Leukemia|Liver Cancer|Neuroblastoma|Ovarian Cancer|Sarcoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Trabectome Versus Trabeculectomy With Mitomycin C in Patients With Open Angle Glaucoma
Status: TERMINATED
Conditions: Open Angle Glaucoma
Interventions: PROCEDURE: Trabectome-IOL|PROCEDURE: Trab-IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of PEEP on Subdural Pressure, Optic Nerve Sheath Diameter, Lung Compliance and Brain Perfusion Pressure
Status: UNKNOWN
Conditions: Supratentorial Neoplasms|Anesthesia, General|Optic Nerve
Interventions: PROCEDURE: PEEP variations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Peg-Intron and Rebetol Therapy in Treatment of Naive Hepatitis C Patients: A Comparison of Race and Genotype on Treatment Outcome (Study P04212)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: peginterferon alfa-2b|DRUG: ribavirin|BIOLOGICAL: peginterferon alfa-2b|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Action Observation Therapy Via Telerehabilitation on Total Knee Arthroplasty Surgery
Status: RECRUITING
Conditions: Knee Arthroplasty, Total|Telerehabilitation
Interventions: OTHER: Standard exercise program based on telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical vs. Alcohol Separation of the Corneal Epithelium During Surface Ablation Refractive Procedures
Status: COMPLETED
Conditions: Keratomileusis, Laser In Situ
Interventions: PROCEDURE: LASIK surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Systemic Therapy in Combination With Stereotactic Radiotherapy in Patients With Metastatic Colorectal Cancer up to 10 Metastatic Sites
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer|Oligometastatic Disease
Interventions: RADIATION: Stereotactic body radiation therapy (SBRT)|DRUG: Maintenance therapy (CAP-B or 5-FU/LV plus bevacizumab.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Cyclophosphamide Plus Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refractory Hodgkin's Disease or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cyclophosphamide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Cross Over Study to Prove Bioequivalence Between Two Brands of Cefalexin Suspension
Status: COMPLETED
Conditions: Anti-Infective Agents
Interventions: DRUG: Cephalexin suspension (Optocef, BAYO5448 )|DRUG: Cephalexin suspension (Keflex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension
Status: COMPLETED
Conditions: Drug Resistant Partial Onset Seizure
Interventions: DRUG: ganaxolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging
Status: COMPLETED
Conditions: Asthma
Interventions: COMBINATION_PRODUCT: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mycobacterium w Plus Docetaxel for Hormone Refractory Metastatic Prostate Cancer
Status: TERMINATED
Conditions: Hormone Refractory Prostate Cancer
Interventions: BIOLOGICAL: Mycobacterium w.|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita
Status: COMPLETED
Conditions: Pachyonychia Congenita
Interventions: DRUG: QTORIN 3.9% rapamycin anhydrous gel|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Basiliximab for the Treatment of Acute Graft-versus-host Disease After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Graft vs Host Disease|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Basiliximab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of Dexmedetomidine and Esketamine Combined Infusion Undergoing Modified Radical Mastectomy
Status: COMPLETED
Conditions: Dexmedetomidine, Esketamine, Postoperative Pain and Recovery Quality
Interventions: DRUG: Dexmedetomidine infusion|DRUG: Co-administration dexmedetomidine and low-dose esketamine infusion|DRUG: Co-administration dexmedetomidine and high-dose esketamine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of SKI2670
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: SKI2670|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Schroth Exercise Trial for Scoliosis
Status: COMPLETED
Conditions: Scoliosis
Interventions: OTHER: The Schroth exercises treatment|OTHER: Global Postural Re-Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers
Status: COMPLETED
Conditions: Esophagitis|Gastroesophageal Reflux|Stomach Ulcer|Duodenal Ulcer
Interventions: DRUG: S-Tenatoprazole-Na (STU-Na)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Taping Techniques in Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis|Pain|Foot Diseases
Interventions: DEVICE: Extracorporeal Shockwave Therapy (ESWT)|OTHER: Low-Dye Taping|OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brief Intervention for School Clinicians (BRISC)
Status: UNKNOWN
Conditions: Emotional/Behavioral Function|Academic Performance
Interventions: BEHAVIORAL: BRISC|BEHAVIORAL: SAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: Nicotinamide Riboside supplementation 1000mg daily in total|DIETARY_SUPPLEMENT: Nicotinamide Riboside dose escalation (up to 3000 mg daily in total)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tension Free Vaginal Tape (TVT) Versus the Miniarc Sling
Status: COMPLETED
Conditions: Urodynamic Stress Incontinence
Interventions: DEVICE: Tension Free Vaginal Tape|DEVICE: Miniarc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reduction or Discontinuation of CNI's With Conversion to Everolimus-Based Immunosuppresion
Status: UNKNOWN
Conditions: Kidney Diseases
Interventions: DRUG: adding Certican to therapy|DRUG: reducing Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing the Risk of Osteoporotic Fracture in Premenopausal Women by a Spa Residential Physical Activity Program
Status: UNKNOWN
Conditions: Osteoporotic Fracture
Interventions: BEHAVIORAL: 9 days spa residential program|BEHAVIORAL: 3 sessions of 10 minutes per day of physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phonak Behind-The-Ear Quality Evaluation
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: DEVICE: Phonak Naida BTE hearing aid|DEVICE: Phonak Naida legacy BTE hearing aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Bevacizumab Therapy With or Without Erlotinib for First-Line Treatment of Non-Small Cell Lung Cancer (ATLAS)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: bevacizumab|DRUG: placebo|DRUG: erlotinib HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bio-equivalence Study Comparing Permethrin Cream, 5% With Elimite in Patients With Active Scabies.
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Permethrin Cream, 5%|DRUG: Elimite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MOTIVATE AF Motivational Support for Patients With Atrial Fibrillation to Promote Weight Loss
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: OTHER: Weight Watchers|OTHER: Slimming world|OTHER: Leeds 'One You'|OTHER: NHS Choices|OTHER: 5:2 diet|OTHER: Individuals own personal plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT: Effect of Late vs Early Introduction of Gluten-free Oats on Patients With Newly Diagnosed Celiac Disease.
Status: RECRUITING
Conditions: Celiac Disease|Gluten Sensitivity|Gluten Allergy|Gluten Enteropathy
Interventions: OTHER: gluten-free oats
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Methylphenidate Treatment Response Study of Genetic Polymorphism in Attention Deficit Hyperactivity Disorder(ADHD)
Status: UNKNOWN
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation of Carotid Artery Plaque Inflammation, Covert Stroke and White Matter Disease
Status: TERMINATED
Conditions: TIA|Stroke|Carotid Artery Stenosis
Interventions: RADIATION: PET/CT imaging with F-18 fluorodeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Prostatic Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DEVICE: Prostate Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Migraine Prevention
Status: TERMINATED
Conditions: Migraine Headache
Interventions: DRUG: Placebo|DRUG: LY2300559
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy
Status: UNKNOWN
Conditions: Unresectable Metastatic Colorectal Cancer
Interventions: DRUG: fruquintinib plus capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacology Trial to Investigate the Dose of OPC-61815 Injection Equivalent to Tolvaptan 15-mg Tablet in Patients With Congestive Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: OPC-61815 injection 2mg|DRUG: OPC-61815 injection 4mg|DRUG: OPC-61815 injection 8mg|DRUG: OPC-61815 injection 16mg|DRUG: Tolvaptan tablet 15mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplementation in Cognitive Aging
Status: COMPLETED
Conditions: Cognitive Aging
Interventions: DIETARY_SUPPLEMENT: Concord grape juice|DIETARY_SUPPLEMENT: placebo juice|DIETARY_SUPPLEMENT: blueberry juice|DIETARY_SUPPLEMENT: whole fruit blueberry powder|DIETARY_SUPPLEMENT: berry placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage - Pilot Study
Status: WITHDRAWN
Conditions: Subarachnoid Hemorrhage|Seizures
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and Thalidomide
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Pamidronate|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Approach for High-risk Patients Leading to Early Diagnosis of Canadians With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Us2.ai (AI-enabled report) handheld echocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Caffeine on EEG Theta/Beta Ratio and Cognitive Control
Status: COMPLETED
Conditions: Caffeine
Interventions: DIETARY_SUPPLEMENT: Caffeine (200mg)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE