pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Anesthesic Techniques for Surgery of the Anterior Cruciate Ligament of the Knee in Ambulatory Surgery. Randomized Pilot Monocentric Trial
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: PROCEDURE: Femoral nerve block|PROCEDURE: obturator nerve block|PROCEDURE: intraarticular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Combined With Adjuvant Chemotherapy and Antivascular Therapy Versus Chemotherapy Alone in Patients With Operable Triple-negative Breast Cancer
Status: RECRUITING
Conditions: TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: epirubicin,cyclophosphamide,paclitaxel,Carrelizumab|DRUG: epirubicin,cyclophosphamide,paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hysterectomy and Levonorgestrel Releasing Intrauterine System (LNG-IUS) in the Treatment of Menorrhagia
Status: COMPLETED
Conditions: Menorrhagia
Interventions: DRUG: LNG-IUS|PROCEDURE: Hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Vision Study Comparing EV Training vs. CCTV for AMD Rehabilitation
Status: COMPLETED
Conditions: AMD
Interventions: BEHAVIORAL: eccentric viewing (EV) training|DEVICE: Closed circuit television (CCTV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Opioid Free Anesthesia-Analgesia Strategy and Surgical Stress in Elective Open Abdominal Aortic Aneurysm Repair
Status: RECRUITING
Conditions: Elective Surgical Procedures|Postoperative Pain|Anesthesia|Opioid Use|Abdominal Aortic Aneurysm Without Rupture|Vascular Surgical Procedure|Interleukin 6|Immunomodulators
Interventions: DRUG: Opioid-Based Anesthesia-Analgesia Strategy|DRUG: Opioid-free Anesthesia-Analgesia Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Mobilization Techniques for the Hemiplegic Shoulder
Status: COMPLETED
Conditions: Hemiplegic Shoulder|Mobility Limitation
Interventions: OTHER: Glenohumeral mobilization|OTHER: Scapular mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects on the Skin of Different Materials Used in Orogastric Tube Detection in Premature Babies
Status: NOT_YET_RECRUITING
Conditions: Neonatal Skin Conditions
Interventions: OTHER: Hydrocolloid dressing|OTHER: Hypoallergenic Flexible
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Study Tests How BI 655130 Works in Patients With Active Ulcerative Colitis. The Study Also Tests How Well BI 655130 is Tolerated and Whether it Helps the Patients
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Spesolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tc99m Macroaggregated Albumin Bronchial Artery Study
Status: WITHDRAWN
Conditions: Hemoptysis|Malignant Neoplasm|Lung Cancer
Interventions: PROCEDURE: Technicium 99 MAA infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Postoperative Oral Carbohydrate Administration in Total Knee Arthroplasty Elderly Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty|Postoperative Oral Carbohydrates|Postoperative Recovery|Elderly Patients
Interventions: COMBINATION_PRODUCT: 100ml carbohydrate containing 12.5g maltodextrin, fructose and glucose|OTHER: Routine feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cantharidin-induced Skin Blister for Testing Anti-inflammatory Effects of Macrolides
Status: COMPLETED
Conditions: Inflammation
Interventions: OTHER: Cantharidin|DRUG: Azithromycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Burosumab in Patients Less Than 1 Year of Age
Status: COMPLETED
Conditions: X-linked Hypophosphatemia (XLH)
Interventions: DRUG: Burosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics and Safety of VX-548 in Participants With Mild or Moderate Hepatic Impairment
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: VX-548
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antibiotic Prophylaxis When Removing Ureteric Stent After Stone Surgery
Status: UNKNOWN
Conditions: Ureteric Stent After Stone Surgery
Interventions: DRUG: Trimetoprim-Sulfa (Bactrim)|OTHER: No antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasal Airway Stent (Nastent®) Study in OSA
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Nastent® (a distally perforated soft silicon nasal tube)|DIAGNOSTIC_TEST: Polygraphy with WatchPAT™ 300
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: DRUG: Placebo oral capsule|DRUG: NYX-783
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment and Management of Chronic Dyspepsia in Eastern Uganda
Status: COMPLETED
Conditions: Helicobacter Pylori Infection|Dyspepsia
Interventions: DRUG: Clarithromycin 500mg|DRUG: Amoxicillin 1000 MG|DRUG: Omeprazole 40 MG|DRUG: Omeprazole 20 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Understand the Impact of Therapy With Tumour Treating Fields (TTFields) in NSCLC
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer|EGFR Gene Mutation|Immune Checkpoint Inhibitor
Interventions: DEVICE: concomitant TTFields treatment device to standard of care EGFR positive NSCLC treatment|DEVICE: concomitant TTFields treatment device to standard of care anti PD-1 NSCLC treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia
Status: COMPLETED
Conditions: X-linked Hypophosphatemic Rickets/Osteomalacia
Interventions: DRUG: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gamification to Increase Mobility in the Hospital
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Coronary Heart Disease|Hypertension|Diabete Mellitus|Dyslipidemias|Obesity|Heart Failure
Interventions: BEHAVIORAL: Gamification Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of ADCT-402 in Patients With Relapsed or Refractory B-cell Lineage Acute Lymphoblastic Leukemia (B-ALL)
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: ADCT-402
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Examine the Safety, Tolerability and Biological Effects of Single Doses of Subcutaneously and Intravenously Administered Pozelimab as Monotherapy and in Combination With Single Doses of Subcutaneously Administered Cemdisiran in Adult Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pozelimab|DRUG: Cemdisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Androgenetic Alopecia in Females, 12 Beam
Status: COMPLETED
Conditions: Androgenetic Alopecia|Hair Loss|Female Pattern Baldness
Interventions: DEVICE: HairMax LaserComb 2009 model 12 beam|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crisis Resource Management Improvement Through Intellectual Questioning of Authority
Status: COMPLETED
Conditions: Medical Education, Simulation, Crisis Resource Management
Interventions: OTHER: Crisis Resource Management Skill Training|OTHER: Standard ACLS Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Do we Intubate Faster With the Videolaryngoscope?
Status: COMPLETED
Conditions: Laryngoscopy|General Anesthesia
Interventions: DEVICE: intubation by direct laryngoscopy|DEVICE: Intubation by videolaryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Ispronicline (TC-1734-112) in Subjects With Age Associated Memory Impairment (AAMI)
Status: COMPLETED
Conditions: Age-Related Memory Disorders
Interventions: DRUG: ispronicline (nicotinic acetylcholine receptor agonist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism
Status: RECRUITING
Conditions: Healthy Diet|Obesity
Interventions: OTHER: Ultra-processed food, high energy density|OTHER: Ultra-processed food, both low|OTHER: Ultra-processed food, both high|OTHER: Unprocessed food diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-guided Monopolar Versus Bipolar Radiofrequency Ablation for Genicular Nerves in Chronic Knee Osteoarthritis
Status: UNKNOWN
Conditions: Chronic Knee Osteoarthritis
Interventions: PROCEDURE: Monopolar radiofrequency ablation|PROCEDURE: Bipolar radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: DRUG: Uridine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab and Golimumab Combination Therapy in Participants With Active Psoriatic Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis, Psoriatic
Interventions: DRUG: Guselkumab|DRUG: Golimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphoid Leukemia|Hematopoetic Myelodysplasia|Leukemia, Myelogenous, Chronic|Lymphoma, Non-Hodgkin
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MYL-1402O Compared With Avastin®, in Patients With Stage IV nsNSCLC
Status: COMPLETED
Conditions: NSCLC Stage IV
Interventions: BIOLOGICAL: Bevacizumab as MYL-1402O|BIOLOGICAL: Bevacizumab as Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Fluid Administration 1 Hour Before Surgery on Preoperative Anxiety and Gastric Volume in Pediatrics
Status: COMPLETED
Conditions: Preoperative Anxiety
Interventions: DIETARY_SUPPLEMENT: Fasting|DIETARY_SUPPLEMENT: Water|DIETARY_SUPPLEMENT: Carbohydrate fluid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Combination of Polyphenol-rich Extracts, Prebiotics, and Hydrolyzed Fiber on the Quality of Life of Patients With Irritable Bowel Syndrome (IBS)
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic, Prebiotic, Polyphenol-rich Extracts|DIETARY_SUPPLEMENT: Probiotic, Prebiotic|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Two Different Modes of Polarized Polychromatic Non-coherent Light Therapy on Jumper's Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Jumper's Knee
Interventions: DEVICE: Bioptron|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Blood-Bile Ratio Tacrolimus After Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplant; Complications|Immunosuppression|Transplant Failure|Transplant; Complication, Rejection
Interventions: DIAGNOSTIC_TEST: Blood-Bile Ratio of Tacrolimus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HealthMatters@24/7 eLearning for People Supporting Adults With Intellectual and Developmental Disabilities
Status: COMPLETED
Conditions: Obesity|Hypertension|Hypercholesterolemia|Hyperglycemia
Interventions: OTHER: Asynchronous, eLearning Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Study (Everyone Who Participates Receives Drug) to Further Determine How Safe and Effective Oral Treatment of Seletracetam is in Patients With Refractory Epilepsy.
Status: WITHDRAWN
Conditions: Epilepsy
Interventions: DRUG: Seletracetam (ucb 44212)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Trial of Intravenous Immune Globulin (IVIG)in Treating Spinocerebellar Ataxias
Status: UNKNOWN
Conditions: Spinocerebellar Ataxias
Interventions: DRUG: Intravenous Immune Globulin (IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIND: Artemis in the Removal of Intracerebral Hemorrhage
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Hemorrhage|Brain Hemorrhage|Cerebral Parenchymal Hemorrhage|Intracerebral Hemorrhage
Interventions: DEVICE: Artemis + Medical Management|OTHER: Best Medical Management Alone (MM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome
Status: TERMINATED
Conditions: Hereditary Breast and Ovarian Cancer|Lynch Syndrome
Interventions: OTHER: Families Accelerating Cascade Testing Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Addressing Social Vulnerabilities in Cardiovascular Disease
Status: UNKNOWN
Conditions: Congestive Heart Failure|Ischemic Heart Disease|Acute Myocardial Infarction|Coronary Artery Disease
Interventions: OTHER: Socially Enhanced Transitional Care Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Wear Experience With One Week Reusable Contact Lenses in Habitual Two Week Reusable Lens Wearers
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Biweekly replacement contact lenses|DEVICE: One week replacement contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II
Status: COMPLETED
Conditions: Overweight and Obesity|Health Behavior|Sleep Deprivation
Interventions: OTHER: Healthy Detours App|OTHER: Fat Secret App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Exposure During Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Cholangiopancreatography, Endoscopic Retrograde|Occupational Exposure|Radiation Injuries
Interventions: RADIATION: PDSa|RADIATION: PDSb
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Trastuzumab Emtansine Plus Pertuzumab Compared With Chemotherapy Plus Trastuzumab and Pertuzumab for Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Vitamin D Supplementation in Chronic Spontaneous Urticaria
Status: UNKNOWN
Conditions: Urticaria
Interventions: DRUG: Vitamin D3 (High dose)|DRUG: Vitamin D3 (Low dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Matching Genotypes and Serotonergic Medications for Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Ondansetron and Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparing Hydrus Microstent(TM) to the iStent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Pseudoexfoliative Glaucoma|Pigmentary Dispersion Glaucoma
Interventions: DEVICE: Hydrus Microstent|DEVICE: iStent Trabecular Micro Bypass|PROCEDURE: Cataract removal and intraocular lens (IOL) implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dexlansoprazole MR on Maintaining Healing in Subjects With Healed Erosive Esophagitis
Status: COMPLETED
Conditions: Esophagitis, Reflux|Esophagitis, Peptic
Interventions: DRUG: Dexlansoprazole MR|DRUG: Dexlansoprazole MR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Differences in the Extent and Rate of Absorption of Doxylamine/Pyridoxine From 2 Different Products Under Fasting Conditions
Status: WITHDRAWN
Conditions: Bioavailability
Interventions: DRUG: doxylamine succinate 10 mg/pyridoxine hydrochloride 10 mg combination|DRUG: Diclegis (Registered Trademark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Lorazepam Versus Intramuscular Paraldehyde in Paediatric Convulsions
Status: COMPLETED
Conditions: Status Epilepticus|Convulsions
Interventions: DRUG: intranasal lorazepam|DRUG: intramuscular paraldehyde
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Centralized Prescribing for Statins
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperlipidemias
Interventions: BEHAVIORAL: Non-visit Based Intervention|BEHAVIORAL: Visit-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Protracted Etoposide During Induction Therapy for High Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: Protracted Oral Etoposide|DRUG: Doxorubicin|DRUG: IV Bolus Etoposide|DRUG: Cisplatin|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: Hematopoietic Factor|PROCEDURE: Primary tumor resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Training During Radiation Therapy for Pharyngeal or Laryngeal Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Pharyngeal Cancer|Laryngeal Cancer
Interventions: BEHAVIORAL: Nutrition Counseling|BEHAVIORAL: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Varisolve® Procedure for Treatment of Varicose Veins in Patients With Right-to-left Cardiac Shunt
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DRUG: Polidocanol (1%) Microfoam (Varisolve)|PROCEDURE: Endovenous Microfoam Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell (DC)/Myeloma Fusions in Combination With Nivolumab in Patients With Relapsed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Nivolumab|BIOLOGICAL: DC/myeloma fusions/GM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
Status: COMPLETED
Conditions: Distal Femur Fracture|Tibial Plateau Fracture|Distal Tibia Fracture|Pilon Fracture
Interventions: OTHER: AlterG anti-gravity treadmill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Cancer|Malignancy|Malignant Neoplasm|Neuropathy|Neuropathies Sensory|Chemotherapy-induced Peripheral Neuropathy
Interventions: DEVICE: Neurosensory testing with Pressure-Specified Sensory Device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemoglobin Optimization to Prevent Transfusion and Adverse Events in Perioperative Patients With Iron Restricted Anemia
Status: TERMINATED
Conditions: Anemia, Iron Deficiency|Anemia of Chronic Disease|Hip Arthropathy|Knee Arthropathy
Interventions: DRUG: Iron sucrose|DRUG: Epoetin Alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tranexamic Acid on Prevention of Recurrence of Hemoptysis
Status: WITHDRAWN
Conditions: Hemoptysis
Interventions: DRUG: tranexamic acid, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Versus Percutaneous Drainage For Hilar Block in Gall Bladder Cancer
Status: COMPLETED
Conditions: Gallbladder Cancer|Obstructive Jaundice
Interventions: PROCEDURE: Endoscopic biliary stenting, Percutaneous biliary stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Oral and Intravenous Ibuprofen for PDA Treatment in Premature Infants
Status: UNKNOWN
Conditions: Extremely Premature Infants|PDA|Oral Ibuprofen|IV Ibuprofen
Interventions: DRUG: iv ibuprofen|DRUG: oral ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Community-based Screening and Treatment of Malaria in Pregnancy: a Cluster-randomized Trial
Status: COMPLETED
Conditions: Malaria, Antepartum|Maternal Malaria During Pregnancy - Baby Not Yet Delivered|Small for Gestational Age (Disorder)
Interventions: OTHER: community based screening and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Syringe-free In-plane Techniques in Ultrasound-guided Central Venous Catheterization
Status: UNKNOWN
Conditions: Central Venous Catheter Placement
Interventions: PROCEDURE: Central venous catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amyloid Imaging And Safety Study Of ACC-001 In Subjects With Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: ACC-001 3 μg/ QS-21 50 μg|BIOLOGICAL: ACC-001 10 μg/ QS-21 50 μg|OTHER: Placebo- Phosphate buffered saline (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E-health Psychological Intervention in Pregnant Women Exposed to Intimate Partner Violence (eIPV)
Status: COMPLETED
Conditions: Pregnancy Related|Violence, Gender-Based|Intimate Partner Violence
Interventions: BEHAVIORAL: e-health psychological counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache
Status: UNKNOWN
Conditions: Chronic Cluster Headache
Interventions: DEVICE: ATI Neurostimulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion
Status: COMPLETED
Conditions: Catheter Obstruction|Vascular Access Devices
Interventions: DRUG: Actilyse|DRUG: Saline solution|DRUG: Actilyse|DRUG: Actilyse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric Varices
Status: COMPLETED
Conditions: Gastric Varices|Portal Hypertension
Interventions: DRUG: Lipiodol|DRUG: Lauromacrogol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease
Status: COMPLETED
Conditions: Charcot Marie Tooth Disease
Interventions: DRUG: Coenzyme Q10|DIETARY_SUPPLEMENT: Coenzyme Q10
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B
Status: COMPLETED
Conditions: Severe Hemophilia B
Interventions: DRUG: Factor IX (rFIXFc)|DRUG: rFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Improve Home Exercise Compliance in Patients With Scoliosis: the Use of a Mobile Application
Status: UNKNOWN
Conditions: Scoliosis
Interventions: DEVICE: Scoliogold App|OTHER: Pre-Formatted Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics
Status: COMPLETED
Conditions: Obesity|Diabetes
Interventions: DRUG: BYETTA treatment|DRUG: Metformine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of an Adjuvanted Inactivated Subunit Influenza Vaccine to Those of a Non-adjuvanted Inactivated Subunit Influenza Vaccine, When Administered to Adults Affected by Chronic Diseases
Status: COMPLETED
Conditions: Influenza Disease
Interventions: BIOLOGICAL: Adjuvanted influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Study With Paclitaxel +/- Ramucirumab in Patients With Squamous-cell Carcinoma of the Esophagus After Prior Therapy
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of the Esophagus
Interventions: DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Amaranth Medical FORTITUDE Bioresorbable Drug-Eluting Coronary Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: AmM FORTITUDE Bioresorbable Drug-Eluting Coronary Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Assessing Changes in Blood Sugar and the Number of Periods Where Supplementation of Carbohydrate is Needed to Treat Low Blood Sugar, During Two Different Treatment Regimens of NN1250 in Type 1 Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin degludec|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: H7 Influenza Prime-Boost Regimens in Healthy Adults: Recombinant H7 DNA Plasmid Vaccine, VRC-FLUDNA071-00-VP, Administered Alone or With Monovalent Influenza Subunit Virion H7N9 Vaccine (MIV) as Prime With MIV Boost Compared to MIV Prime With MIV Boo...
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: A/Shanghai/02/2013 (H7N9) MIV|BIOLOGICAL: VRC-FLUDNA071-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validity and Reliability of a Depth Camera-based Automated Physical Function and Fall Risk Assessments
Status: COMPLETED
Conditions: Fall|Healthy Aging
Interventions: DIAGNOSTIC_TEST: Azure Kinect-based Tandem Stance Test (ATST) and Physical Therapist's Measurements of Tandem Stance Test (PTST)|DIAGNOSTIC_TEST: Azure Kinect-based Five Times Sit-to-Stand Test (AFTSS) and Physical Therapist's Measurements of Five Times Sit-to-Stand Test (PFTSS)|DIAGNOSTIC_TEST: Azure Kinect-based Timed Up and Go Test (ATUG) and Physical Therapist's Measurements of Timed Up and Go Test (PTUG)|DIAGNOSTIC_TEST: Short Physical Performance Battery (SPPB)|DIAGNOSTIC_TEST: Berg Balance Scale (BBS)|DIAGNOSTIC_TEST: Functional Reach Test (FRT)|DIAGNOSTIC_TEST: Four-Square Step Test (FSST)|DIAGNOSTIC_TEST: Grip Strength (GS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Effect of a Nutritional Supplement on Mental Wellness in Adults
Status: RECRUITING
Conditions: Low Mood
Interventions: DIETARY_SUPPLEMENT: Intervention 1 - Triglyceride|DIETARY_SUPPLEMENT: Intervention 2 - Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Metformin in a Non-Diabetic Patient Population
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DRUG: MetFORMIN Hydrochloride ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cefiderocol Pharmacokinetics in Adult Patients With Cystic Fibrosis
Status: RECRUITING
Conditions: Cystic Fibrosis|Pneumonia, Bacterial
Interventions: DRUG: Cefiderocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Total Placenta Previa Associated With the Placenta Accreta Spectrum.
Status: COMPLETED
Conditions: Maternal; Procedure
Interventions: PROCEDURE: Peripartum total abdominal hysterectomy (p-TAH)|PROCEDURE: Cesarean Section (C/S)|OTHER: Neonatal mortality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ramucirumab + Pembrolizumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Ramucirumab|DRUG: Pembrolizumab|OTHER: EORTC QLQ-30|OTHER: FACT H&N|PROCEDURE: Peripheral blood
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of New Salivary Biomarkers to Evaluate Excessive Diurnal Sleepiness in Children With Hypersomnia
Status: RECRUITING
Conditions: Hypersomnia|Sleepiness, Excessive Daytime
Interventions: BIOLOGICAL: saliva samples|BEHAVIORAL: Stanford sleepiness scale|BEHAVIORAL: Karolinska Sleepiness Scale|BEHAVIORAL: Epworth Sleepiness Scale|BEHAVIORAL: BLAST test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Hydrolyzed Ginseng Extract on Impaired Fasting Glucose
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: HGE (hydrolyzed ginseng extract)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Effects of CBN With and Without CBD on Sleep Quality
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: CBN and CBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)
Status: RECRUITING
Conditions: Glioma|Glioma, Malignant|Glioblastoma|Glioblastoma Multiforme|Glioblastoma Multiforme of Brain|GBM|Brain Cancer|High Grade Glioma
Interventions: PROCEDURE: Laparoscopically harvested omental tissue autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Front-line Therapy With Carfilzomib, Lenalidomide, and Dexamethasone Induction
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib/Lenalidomide/Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Progressive Muscle Relaxation Exercises During Pregnancy.
Status: RECRUITING
Conditions: Lumbopelvic Pain|Insomnia
Interventions: OTHER: Progressive Muscle Relaxation Exercises|OTHER: Conventional Therapy(Hot pack,TENS,Patient Education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recurrence Rate of Hemorrhoidal Disease at 10 Years and More After HAL Doppler or HAL-RAR Intervention
Status: RECRUITING
Conditions: Hemorrhoidal Disease
Interventions: PROCEDURE: HAL (Hemorrhoidal Artery Ligation) - RAR (Recto-Anal Repair)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: We Designed and Implemented the 'MASTER Framework' as a Theoretical Framework to Guide the Design and Delivery of PE and Sports.
Status: NOT_YET_RECRUITING
Conditions: Help PE Teachers Learn and Develop the Critical Skills Needed to Create a Positive Teaching Environment
Interventions: BEHAVIORAL: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.
Status: UNKNOWN
Conditions: Oropharynx Squamous Cell Carcinoma|Larynx Squamous Cell Carcinoma|Hypopharynx Squamous Cell Carcinoma|Oral Cavity Squamous Cell Carcinoma
Interventions: BIOLOGICAL: IO102|BIOLOGICAL: IO103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Montelukast Have an Affect on the Function of the Artery in Patients With Heart Disease
Status: TERMINATED
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DRUG: Montelukast Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Baricitinib|DRUG: TNF Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Hattler Respiratory Assist Catheter in Severe Respiratory Failure
Status: WITHDRAWN
Conditions: Emphysema|Acute Respiratory Distress Syndrome|Chronic Obstructive Pulmonary Disease|Asthma|Respiratory Insufficiency
Interventions: DEVICE: Hattler Respiratory Assist Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Urethral Stricture
Interventions: DEVICE: Optilume Drug Coated Balloon (DCB)|DEVICE: Control Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Profiling Antibody Status and Vaccine Effectiveness in Post Vaccination With SARS CoV2 in Ain Shams University
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: Astrazeneca/Oxford Vaccine|BIOLOGICAL: Sinopharm vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulmonary Watershed Topographic Map Navigation for Lung Nodule Resection
Status: RECRUITING
Conditions: Pulmonary Function Assessment|Disease Free Survival|NSCLC, Stage I
Interventions: PROCEDURE: Wedge resection under watershed analysis method
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Self-Help for Parents of Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: CBT Based Self-help Workbook + Counseling Telepho
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Sennosides With Pico Salax in Bowel Preparation for Colonoscopy: a Study of Optimal Dose and Timing
Status: COMPLETED
Conditions: Colonoscopy Preparation Outcome
Interventions: DRUG: Sennosides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Visual Acuity With a Reusable Toric Multifocal Contact Lens
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: Bausch + Lomb Ultra® Multifocal for Astigmatism
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Placebo (saline)|OTHER: Background hormonal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas
Status: RECRUITING
Conditions: Soft Tissue Sarcoma Adult|Advanced Soft-tissue Sarcoma|Ewing Sarcoma|Osteosarcoma|Undifferentiated Pleomorphic Sarcoma
Interventions: DRUG: Association of pembrolizumab + cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies
Status: TERMINATED
Conditions: Haematological Malignancies
Interventions: DRUG: AS703569|DRUG: AS703569
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LITES Task Order 0005 Prehospital Airway Control Trial (PACT)
Status: RECRUITING
Conditions: Trauma Injury|Airway Control
Interventions: DEVICE: Supraglottic airway device|OTHER: Standard airway management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Insulin Peglispro (LY2605541) in Participants With Type 2 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Peglispro|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Pharmacokinetic Properties of Two Tablet Formulations of Macitentan in Healthy Adults
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Treatment A (adult formulation)|DRUG: Treatment B (pediatric formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Influence of Nutrition on Lung Microbiota in Traumatic Brain Injury
Status: RECRUITING
Conditions: Microbial Colonization
Interventions: DIETARY_SUPPLEMENT: standard enteral nutrition|DIETARY_SUPPLEMENT: specialized nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of HM10760A (Long-acting Erythropoietin (EPO)) in Healthy Korean Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HM10760A or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adaptive Cell Phone Support to Promote Medication Adherence
Status: RECRUITING
Conditions: Medication Adherence
Interventions: BEHAVIORAL: Adaptive Cell Phone Support|BEHAVIORAL: Computer-Delivered Cell Phone Support|BEHAVIORAL: Automated Text Reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Investigational Study to Assess Efficacy and Pattern of Use of SM-1 in Subjects With a History of Transient Insomnia
Status: WITHDRAWN
Conditions: Transient Insomnia
Interventions: DRUG: SM-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly
Status: COMPLETED
Conditions: Hyperhomocysteinemia
Interventions: DIETARY_SUPPLEMENT: Low-dose complex B-vitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Unilateral Neck Radiotherapy in Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Neoplasms
Interventions: RADIATION: Radiotherapy to ipsilateral neck lymphatics and tumor bed (radiotherapy to one side of the neck)|RADIATION: Radiotherapy to the bilateral neck lymphatics and tumor bed (radiotherapy to both sides of the neck)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Dietary Proteins on Postprandial Lipemia, Incretin Responses and Subclinical Inflammation in Obese Subjects
Status: COMPLETED
Conditions: Obesity|Postprandial Lipemia|Atherosclerosis|Inflammation|Postprandial Incretins
Interventions: DIETARY_SUPPLEMENT: Caseine|DIETARY_SUPPLEMENT: Cod|DIETARY_SUPPLEMENT: Gluten|DIETARY_SUPPLEMENT: Whey Isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION