pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tetracycline as a Prophylaxis for Rash in Patients With NSCLC Receiving Treatment With BIBW2992 (Afatinib)
Status: COMPLETED
Conditions: Skin Rash|Lung Cancer
Interventions: DRUG: Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3, Randomized, Safety, Lot Consistency and Clinical Benefit Study of Recombinant Botulinum Vaccine A/B
Status: WITHDRAWN
Conditions: Botulism
Interventions: BIOLOGICAL: rBV A/B|BIOLOGICAL: Placebo (USP sterile saline for injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication
Status: RECRUITING
Conditions: Pregnancy|Postpartum Depression|Infant Development|Infant Conditions
Interventions: BEHAVIORAL: Rosie the Chatbot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The VEPRO Trial: A Cross-Over Randomised Controlled Trial Comparing 2 Corrective Lenses for Patients With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: a new generation of corrective lens for presbyopia (i.e., Varilux Panamic Orma Crizal)|DEVICE: an old generation of corrective lens for presbyopia (i.e., Varilux Comfort Orma Crizal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Gardasil and Twinrix and the Effect of a Dose of Gardasil or Cervarix Given 42 Months Later.
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: BIOLOGICAL: Gardasil vaccine, Immunogenicity, Booster dose.|BIOLOGICAL: Cervarix Vaccine, Immunogenicity, Booster Dose.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Efficiency of Computer Guided Ridge Splitting Using Piezosurgery in Horizontally Deficient Posterior Mandible
Status: UNKNOWN
Conditions: Edentulous Patients|Atrophic Posterior Mandible With Insufficient Width
Interventions: DEVICE: Computer Guided ridge splitting in posterior mandible
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Clinical Outcomes in Alzheimer's Disease Agitation
Status: COMPLETED
Conditions: Agitation in Patients With Dementia of the Alzheimer's Type|Alzheimer Disease|Agitation,Psychomotor
Interventions: DRUG: AXS-05|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Focused Techniques on Thigh Muscle Activation After Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Internally Focused Exercise|OTHER: Externally Focused Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Asciminib Used in Consolidation With Imatinib vs. Imatinib to Achieve TFR in CP-CML
Status: RECRUITING
Conditions: Chronic Myeloid Leukemia|Chronic Myeloid Leukemia, BCR/ABL-Positive|Chronic Myeloid Leukemia in Remission
Interventions: DRUG: Asciminib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telehealth Group Counseling and Preventive Care for Women
Status: RECRUITING
Conditions: ASCVD|NSTEMI|STEMI|Coronary Artery Disease|Acute Coronary Syndrome|Myocardial Infarction|Unstable Angina|Chest Pain
Interventions: OTHER: Telehealth Group Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity Study of MEDI-517 (GSK 580299) With or Without Adjuvant in Healthy Adult Females
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: MEDI-517 HPV-16/18 VLP AS04 vaccine|BIOLOGICAL: MEDI-517 HPV-16/18 VLP vaccine with Al(OH)3|BIOLOGICAL: MEDI-517 HPV-16/18 VLP vaccine without adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Study of Apatinib Plus CIK as the Third Line Therapy for Patients With Advanced Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Stomach Neoplasms
Interventions: BIOLOGICAL: Cytokine-Induced Killer Cells|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin Therapy for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DRUG: Erythropoietin|DRUG: Placebo erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Vision Depression Prevention Trial for Age Related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Depression
Interventions: BEHAVIORAL: BA-LVR|BEHAVIORAL: ST-LVR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sleep and Healthy Aging Research on Depression for Younger Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Anhedonia|Depression
Interventions: BIOLOGICAL: Endotoxin|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Enhancing Resiliency and Optimizing Readiness in Military Personnel
Status: RECRUITING
Conditions: Resilience, Psychological|Stress, Physiological
Interventions: BEHAVIORAL: Psychological Flexibility Training (PFT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours
Status: RECRUITING
Conditions: Cancer|Breast Cancer|Prostate Cancer|Colorectal Cancer|Gastro-oesophageal Cancer
Interventions: DRUG: Aspirin 100mg|DRUG: Aspirin 300mg|DRUG: Placebo 100mg|DRUG: Placebo 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase I Study Evaluating the Safety and Pharmacokinetics of Budesonide, Glycopyrronium, and Formoterol Fumarate Inhalation Aerosol (BGF MDI) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Inhaled BGF (PT010) Dose 1|DRUG: Inhaled BGF (PT010) Dose 2|DRUG: Inhaled BGF (PT010) Dose 3|DRUG: Inhaled GFF (PT003)|DRUG: Inhaled Symbicort Dose 1|DRUG: Inhaled Symbicort Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double Blind, Double Dummy, Randomized, Comparative Study Of The Efficacy And Safety Of Valdecoxib 40 Mg Twice Daily, As Needed In The First Menstrual Cycle Day And Then Once A Day, And Piroxicam 40 Mg Once A Day In The Treatment Of Patients With Primary Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DRUG: piroxicam|DRUG: valdecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority of Meningococcal Vaccine GSK134612 Versus Mencevax™ in 11-17 Year-Old Subjects
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612|BIOLOGICAL: Mencevax™ ACWY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Almonds on Vascular Reactivity in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Vascular Disease|Endothelial Dysfunction|Heart Disease|Cardiovascular Diseases|Hypertension
Interventions: DIETARY_SUPPLEMENT: Almonds|DIETARY_SUPPLEMENT: Placebo Comparator:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rotational Stability After Nanoflex Collamer Toric Intraocular Lens Implantation in Astigmatic Patients
Status: UNKNOWN
Conditions: Astigmatism
Interventions: PROCEDURE: Phacoemulsification with toric Nanoflex IOL implantation|DEVICE: NanoFlex toric Intraocular Lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
Status: RECRUITING
Conditions: Psychosis|Negative Symptoms With Primary Psychotic Disorder
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Fat Milk Intake and Cardio Vascular Risk (CVR) Indicators in Children
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Modification of the content of fat in milk|OTHER: Modification of the content of cows milk|OTHER: Modification of the fat content of cows´ milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sevelamer Hydrochloride and Femoral and Carotid Intima Media Thickness Progression in End Stage Renal Disease
Status: COMPLETED
Conditions: End Stage Renal Disease|Hemodialysis|Intimal Media Thickness
Interventions: DRUG: sevelamer hydrochloride|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Ascorbic Acid|DIETARY_SUPPLEMENT: Fish Oil Placebo|DIETARY_SUPPLEMENT: Ascorbic Acid Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Acceptance and Metabolic Effects in Infants Receiving a Novel Low Glycaemic Index follow-on Formula
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: OTHER: Modified infant follow-on formula|OTHER: Standard infant follow-on formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Efficacy and Safety of LEE011 in Men and Postmenopausal Women With Advanced Breast Cancer.
Status: COMPLETED
Conditions: Advanced Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Fulvestrant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Tocilizumab as a Remission-Induction and Glucocorticoid-Sparing Regimen in Subjects With New-Onset Polymyalgia Rheumatica (PMR- SPARE)
Status: COMPLETED
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Tocilizumab Prefilled Syringe [Actemra]|DRUG: Placebos|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Three Different Modalities for Management of Distal Extension Atrophied Mandibular Ridge: A One Year Prospective Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Different Treatment Outcomes of Atrophied Distal Extension Cases
Interventions: PROCEDURE: implant supported prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multivessel Stenting Versus Staged Revascularization With Zotarolimus-eluting Stent for STEMI
Status: UNKNOWN
Conditions: ST Elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Interventions: DEVICE: Zotarolimus-eluting coronary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Faster-acting insulin aspart|DRUG: basal insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Combination of Gemigliptin and Metformin on Microbiota Change
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: gemigliptin/metformin|DRUG: glimepiride/metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Immunogenicity Study of 3 Doses of Opal Immunotherapy in HIV Infected People
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Opal-HIV-Gag(c) Low Dose|BIOLOGICAL: Opal-HIV-Gag(c) Medium dose|BIOLOGICAL: Opal-HIV-Gag(c) High dose|OTHER: Dimethyl Sulfoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Isolating Clostridium Difficile Asymptomatic Carriers on the Incidence of Infections
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: OTHER: Detection and isolation of C. difficile carriers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Training for Emotion Regulation in Psychotic Disorders
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: BEHAVIORAL: Emotional working memory training|BEHAVIORAL: Placebo working memory training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nocturnal TLA for Severe Allergic Asthma After Withdrawal of Omalizumab Therapy
Status: COMPLETED
Conditions: Severe Allergic Asthma
Interventions: DEVICE: Nocturnal Temperature Controlled Laminar Flow Device|OTHER: None Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orelabrutinib and Sintilimab in Relapsed or Refractory Central Nervous System Lymphoma
Status: RECRUITING
Conditions: Primary Central Nervous System Hodgkin Lymphoma
Interventions: DRUG: Orelabrutinib|DRUG: Orelabrutinib|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Binocular Treatment Using a Dichoptic Reading Application in Children With Convergence Insufficiency.
Status: NOT_YET_RECRUITING
Conditions: Ophthalmological Disorder
Interventions: DEVICE: Self-education with dichoptic reading on tablet|PROCEDURE: Conventional orthoptic rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: bosentan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The CaNadian Standardized Pulmonary Rehabilitation Efficacy Trial
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: Canadian Standardized PR|OTHER: Traditional PR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab+Bevacizumab+SBRT in Unresectable HCC
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|RADIATION: Stereotactic body radiation therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulse Width 0.15ms vs 0.30ms in Electroconvulsive Therapy
Status: UNKNOWN
Conditions: Major Depressive Disorder|Bipolar Depression
Interventions: DEVICE: Electroconvulsive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors
Status: TERMINATED
Conditions: Neoplasms|Colorectal Neoplasms|Melanoma|Pancreatic Neoplasms|Sarcoma|Ovarian Neoplasms|Brain Neoplasms|Thyroid Neoplasms|Neuroendocrine Tumors|Cholangiocarcinoma|Salivary Gland Neoplasms|Head and Neck Neoplasms|Thyroid Cancer, Papillary|Lymphoma, Large-Cell, Anaplastic|Neoplasms by Site|Respiratory Tract Neoplasms|Thoracic Neoplasms|Respiratory Tract Diseases|Carcinoma, Bronchogenic|Bronchial Neoplasms|Intestinal Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms|Digestive System Diseases|Gastrointestinal Diseases|Colonic Diseases|Intestinal Diseases|Central Nervous System
Interventions: DRUG: Alectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety Management of Cardiac Toxicity in Breast Cancer Patients Under Multidiscipline Therapy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms|Cardiotoxicity
Interventions: OTHER: limit heart dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of Online Information Cards Education on Women's Perception of Family Planning Behaviors in the Postpartum Period
Status: COMPLETED
Conditions: Obstetric Care of the Giving Birth
Interventions: BEHAVIORAL: Online Information Cards Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016)
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: Dalotuzumab 10 mg/kg|BIOLOGICAL: Cetuximab|DRUG: Irinotecan|BIOLOGICAL: Dalotuzumab 15/7.5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Obesity on the Incidence of Postoperative Cognitive Dysfunction in Gynecological Day Case Surgery
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction
Interventions: BEHAVIORAL: Effect of Obesity on incidence of Postoperative cognitive in Gynecological Day- Day- case surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: FDG-PET and Circulating HPV in Patients With Cervical Cancer Treated With Definitive Chemoradiation (II)
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DIAGNOSTIC_TEST: [18-F]- FDG - PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BLI (Blue Light Imaging) for the Histological Characterization of Colorectal Polyps
Status: COMPLETED
Conditions: Adenoma Colon
Interventions: DEVICE: BLI (Blue Laser Imaging)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: IMGN529 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Chronic Lymphocytic Leukemia
Interventions: DRUG: IMGN529
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Adult and Pediatric Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: denufosol tetrasodium (INS37217) Inhalation Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: MORAb-202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Coronary Artery Disease
Interventions: DRUG: Rivaroxaban|DRUG: Placebo|OTHER: Standard of care for heart failure and coronary artery disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.
Status: COMPLETED
Conditions: Postoperative Pain|Total Shoulder Arthroplasty|Multimodal Analgesia
Interventions: DRUG: HTX-011|DRUG: Bupivacaine Hydrochloride|DRUG: Ibuprofen|DRUG: Acetaminophen|DEVICE: Luer lock applicator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Assessment of Remyelinating Therapy
Status: COMPLETED
Conditions: Acute Optic Neuritis
Interventions: DRUG: Placebo|DRUG: BIIB033 100mg/Kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 14729-D9831C00002- 1 Month Biopsy Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: AZD1981|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IN Sub-Dissociative Ketamine vs IN Fentanyl
Status: COMPLETED
Conditions: Bone Fracture
Interventions: DRUG: ketamine|DRUG: fentanyl|DRUG: ibuprofen or acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Leukocyte Immunophenotype and the Lipid Transport System as Predictive Biomarkers of Severe Bacterial Infections
Status: ENROLLING_BY_INVITATION
Conditions: Sepsis|Infective Endocarditis|Pneumonia, Bacterial
Interventions: DIAGNOSTIC_TEST: Bood leukocyte subsets|DIAGNOSTIC_TEST: The cholesterol content of the cell membrane of T-cells and monocytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple s.c Doses HS-20004 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HS-20004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Clofarabine|DRUG: Fludarabine|DRUG: Busulfan|PROCEDURE: Total Body Irradiation (TBI)|DRUG: Cyclophosphamide|DRUG: Granulocyte Colony-Stimulating Factor|DRUG: Tacrolimus|DRUG: Cellcept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Cervical Stabilization Exercises and Vibration Application in Individuals With Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Chattanooga Stabilizer pressure biofeedback|DEVICE: VibraSens - Focal Vibration Therapy (TechnoConcept - France)|OTHER: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HyaloFAST Trial for Repair of Articular Cartilage in the Knee
Status: ACTIVE_NOT_RECRUITING
Conditions: Defect of Articular Cartilage
Interventions: DEVICE: Hyalofast|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety, Tolerability and Pharmacokinetics of Single and Multiple Dose of SAM-531
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: SAM-531|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A HIV Vaccine Trial in Individuals Who Started Antiretrovirals During Primary or Chronic Infection (EHVA T02)
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: Vaccine and vedolizumab (Entyvio)|BIOLOGICAL: Placebo vaccine and vedolizumab infusion (Entyvio)|BIOLOGICAL: Placebo vaccine and placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Men With Metastatic Castrate-Resistant Prostate Cancer Treated With Either Sipuleucel-T (Provenge®), Abiraterone Acetate (Zytiga®) or Enzalutamide (Xtandi®) Undergoing Cardiopulmonary EXercise Testing
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Abiraterone acetate|DRUG: Sipuleucel-T
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Oral Fluid vs IV Fluid After Primary TKA
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Total Knee Arthroplasty|Oral Fluid Replacement
Interventions: DIETARY_SUPPLEMENT: Oral fluid|DIETARY_SUPPLEMENT: IV fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Check-Cap C-Scan System in Providing Structural Information and Detection of Polypoid Lesions
Status: COMPLETED
Conditions: Polypoid Lesions
Interventions: DEVICE: C-Scan System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Parasitic Clearance and Recurrence Rates Among Patients With Vivax Malaria
Status: UNKNOWN
Conditions: Parasitemia
Interventions: DRUG: Artemisinin combination therapies (ACT)will be used for Chloroquine resistant P.vivax|DRUG: Chloroquine and Primaquine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of a Glutathione Precursor (FT061452),on Serum and Intracellular Glutathione Levels
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DRUG: Placebo low dose|DRUG: N Acetyl cysteine, 600mg (low dose)|DRUG: Proimmune 200 (FT061452) 3000mg low dose|DRUG: Placebo (high dose)|DRUG: N Acetyl cysteine, 1200mg (high dose)|DRUG: FT061452, 6000mg high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Frequency RF Current Effects on Muscle Pain and Function
Status: RECRUITING
Conditions: Transcutaneous Electric Nerve Stimulation|Chronic Low-back Pain|Hamstring Injury|Muscle; Injury, Quadriceps (Thigh)|Physical Therapy|Calf Muscle Pulled
Interventions: DEVICE: Radiofrequency Energy Transfer|DEVICE: Transcutaneous Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
Status: TERMINATED
Conditions: Anterior Ischemic Optic Neuropathy
Interventions: DRUG: Diagnostic procedures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Morning Versus Evening Intake of Simvast Controlled Release (CR) Tablet in Patients With Hyperlipidemia
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: Simvastatin CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Efficacy Study of Nordihydroguaiaretic Acid (NDGA) in Non Metastatic Recurrent Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: Nordihydroguaiaretic Acid (NDGA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-Escalation Therapy for Human Papillomavirus Negative Disease
Status: RECRUITING
Conditions: Human Papilloma Virus|Squamous Cell Carcinoma|Squamous Cell Carcinoma of the Head and Neck|HPV-Related Squamous Cell Carcinoma|HNSCC
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Nivolumab|RADIATION: Radiation|DRUG: Hydroxyurea Pill|DRUG: 5-fluorouracil|DRUG: Filgrastim Injection|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natural History Study of Synucleinopathies
Status: RECRUITING
Conditions: Patients With Synucleinopathies|Neurogenic Orthostatic Hypotension|Pure Autonomic Failure|REM Sleep Behavior Disorder|Parkinson Disease|Dementia With Lewy Bodies|Multiple System Atrophy|Shy-Drager Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of ME1111 in Patients With Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: ME1111 Solution, Low strength|DRUG: ME1111 Solution, High strength|DRUG: Matching Vehicle Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Bortezomib,Bendamustine , Dexamethasone, Patients With Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bortezomib|DRUG: dexamethasone|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine Differentiation
Status: COMPLETED
Conditions: Carcinoma, Large Cell|Neuroendocrine Tumors
Interventions: DRUG: RAD001|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Long-term Safety of (R,R)-Formoterol in Subjects With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Chronic Bronchitis|Emphysema
Interventions: DRUG: arformoterol|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: Itraconazole 100mg capsules|DRUG: Itraconazole 200mg tablets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacodynamic Study Comparing Zegerid® and Prilosec OTC® (CL2007-17 )(P07813)(COMPLETED)
Status: COMPLETED
Conditions: Gastric Acid|Human Experimentation
Interventions: DRUG: Omeprazole/sodium bicarbonate|DRUG: omeprazole magnesium|DRUG: sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Status: COMPLETED
Conditions: Schizophrenic Disorders
Interventions: DEVICE: Transcranial magnetic stimulation: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Refractive Therapy Design Comparison for -4 to -6 Diopter Treatment for Overnight Wear for Myopia
Status: COMPLETED
Conditions: Myopia
Interventions: OTHER: Corneal Refractive Therapy-spherical|OTHER: Corneal Refractive Therapy-aspherical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Water and Land-based Aerobic Training in Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Aquatic Training Plus Health Education|OTHER: Land Training Plus Health Education|OTHER: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baricitinib for the Lung Injury Following Spontaneous SAH
Status: NOT_YET_RECRUITING
Conditions: Spontaneous Subarachnoid Hemorrhage
Interventions: DRUG: Baricitinib 4 MG|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two KADIAN 10 mg Capsules to a KADIAN 20 mg Capsule Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: morphine sulfate extended-release capsules|DRUG: KADIAN (morphine sulfate extended-release) capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
Status: NOT_YET_RECRUITING
Conditions: Recession, Gingival
Interventions: PROCEDURE: Laterally Closed Tunnel with CTG|PROCEDURE: CAF with CTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TAK-935 as an Adjunctive Therapy in Participants With Developmental and/or Epileptic Encephalopathies
Status: COMPLETED
Conditions: Developmental and/or Epileptic Encephalopathies
Interventions: DRUG: TAK-935|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ARTISAN 2.0: Deconstructing the Integrative Efficacy of a Multimodal Art-based Intervention
Status: UNKNOWN
Conditions: Intergenerational Relations|Loneliness|Well Aging
Interventions: BEHAVIORAL: ARTISAN Condition|BEHAVIORAL: Intergenerational Participatory Arts Condition|BEHAVIORAL: Intergenerational Art-space Condition|BEHAVIORAL: Intergenerational Storytelling Condition|BEHAVIORAL: Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United States
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: FTC/TDF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATCF (Azole Therapy in Cystic Fibrosis)
Status: COMPLETED
Conditions: Cystic Fibrosis|Aspergillus Infections
Interventions: DRUG: Itraconazole/voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Assessment of Rapid Endovascular Treatment in Basilar Artery Occlusion Stroke in 115 Hospital
Status: UNKNOWN
Conditions: Stroke, Acute|Basilar Artery Occlusion
Interventions: PROCEDURE: Thromboectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Endurance Exercise Programme Preceded by Ischaemic Preconditioning in Older People
Status: COMPLETED
Conditions: Older People
Interventions: OTHER: IPC + Exercise protocol|OTHER: Sham IPC + Exercise protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Usage of Tramadol With Levobupivacaine for Pain Treatment After Cesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Tramadol infusion via wound catheter|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open-Label, Dose Escalation and Cohort Expansion Study of BS HH 002.SA in Patients With AML and MDS
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
Interventions: DRUG: BS HH 002.SA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Screening With MRI in Women Aged 50-75 Years With Extremely Dense Breast Tissue: the DENSE Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Contrast enhanced breast MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Play Intervention for Dementia for Promoting Cognitive Function: A Feasibility Study
Status: COMPLETED
Conditions: Dementia|Alzheimer Disease
Interventions: BEHAVIORAL: Play Intervention for Dementia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Workload of Water Polo Players Following a Phosphorus Manipulated High Carbohydrate Meal
Status: UNKNOWN
Conditions: Energy Expenditure
Interventions: DIETARY_SUPPLEMENT: phosphorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Trial of Gemcitabine vs S-1 vs Gemcitabine Plus Nab-paclitaxel as Adjuvant Chemotherapy of Post-operative Pancreatic Cancer Patients
Status: UNKNOWN
Conditions: Cancer of Pancreas
Interventions: DRUG: Nab-paclitaxel plus Gemcitabine|DRUG: Gemcitabine monotherapy|DRUG: S-1 monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food for Thought - a Nutrition Intervention for Women Undergoing Active Treatment for Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage II Breast Cancer AJCC V8|Anatomic Stage III Breast Cancer AJCC V8|Triple-Negative Breast Carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Subcutaneously Administered Herceptin (Trastuzumab) in Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Early Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab - intravenous solution|DRUG: Trastuzumab - subcutaneous solution|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Uprifosbuvir (MK-3682) With Ruzasvir (MK-8408) in Adults With Chronic Hepatitis C Genotype 1, 2, 3, 4, 5 or 6 Infection (MK-3682-035)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Uprifosbuvir 450 mg|DRUG: Ruzasvir 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENhancing Maturation of Autogenous Arteriovenous Hemodialysis Access by Aggressive surveillaNCe With Duplex and Endovascular Treatment
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Duplex ultrasonography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plaque Inhibitory Effect of Neutral Electrolysed Water in the Form of a Mouthwash in a 4-day Non-brushing Model
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Neutral electrolyzed water|DRUG: Placebo|DRUG: Chlorhexidine digluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome Post Mastectomy Lymphedema
Status: RECRUITING
Conditions: Carpal Tunnel Syndrome
Interventions: DEVICE: extra corporeal shock wave therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory and Microbiologic Markers in Sputum: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia
Status: COMPLETED
Conditions: Cystic Fibrosis|Primary Ciliary Dyskinesia
Interventions: PROCEDURE: Sputum Collection|PROCEDURE: Pulmonary Function Testing|PROCEDURE: Exhaled Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma|GBM|Newly Diagnosed Glioblastoma
Interventions: DRUG: MN-166|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy Followed by Cetuximab and Radiation Therapy for Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Radiotherapy|DRUG: Leucovorin|BIOLOGICAL: Cetuximab|DRUG: Filgrastim|DRUG: Erythropoetin|DRUG: Cisplatin|DRUG: Fluorouracil|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The 18F Peel-way Sheath Versus the 18F Access Sheath With a Suction-evacuation Function MPCNL for the Management of 2-5cm Size Kidney Stones
Status: UNKNOWN
Conditions: Renal Calculi
Interventions: DEVICE: 18F Peel-Way Sheath|DEVICE: 18F access sheath with a suction-evacuation function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Iterative Redesign of a Multifaceted Implementation Strategy for a School-based Behavioral Skills Intervention (RUBI)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Unadapted Research Units in Behavioral Intervention (RUBI) implementation strategy|BEHAVIORAL: RUBI in Educational Settings (RUBIES)-Team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant
Status: COMPLETED
Conditions: CD20 Positive|Chronic Lymphocytic Leukemia|Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|T-Cell Non-Hodgkin Lymphoma
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Anti-Thymocyte Globulin|DRUG: Bendamustine|BIOLOGICAL: Filgrastim|DRUG: Fludarabine|DRUG: Methotrexate|BIOLOGICAL: Rituximab|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT