pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of Pain During an Abortion With Knowledge of the Predictive Factors of Pain.
Status: COMPLETED
Conditions: Induced Abortion|Medical Abortion|Surgical Abortion|Pain
Interventions: OTHER: Evaluation of pain during voluntary termination of pregnancy with medication following consideration of predictive factors of pain without an established analgesic protocol|OTHER: Evaluation of pain during a voluntary medical termination of pregnancy following consideration of predictive factors of pain with an established analgesic protocol|OTHER: Assessment of pain during voluntary termination of pregnancy by aspiration under local anesthesia following consideration of predictive factors of pain without an established analgesic protocol|OTHER: Assessment of pain during voluntary termination of pregnancy by aspiration under local anesthesia following consideration of predictive factors of pain with established analgesic protocol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Minimizing the Utilization of Voiding Cystourethrography for Patients With Antenatal Hydronephrosis
Status: TERMINATED
Conditions: Antenatal Hydronephrosis|Post-natal Hydronephrosis
Interventions: PROCEDURE: Voiding cystourethrogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Barbed Suture Versus Traditional Suture Material for Laparoscopic Myomectomy
Status: UNKNOWN
Conditions: Fibroids
Interventions: PROCEDURE: Laparoscopic myomectomy with unidirectional barbed suture|PROCEDURE: Traditional suture material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Skills Acquired Through Judo Training on Risk Factors for Falling in Elderly Men and Women
Status: COMPLETED
Conditions: Aging Problems|Frailty|Fall Injury|Accidental Fall|Fear of Falling
Interventions: OTHER: Judo4Balance - 12 week judo inspired exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Individual Cognitive Stimulation at Home in Adults With Psychotic Disorders
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia|Schizoaffective Disorder|Delusional Disorder|Substance-Induced Psychotic Disorder
Interventions: BEHAVIORAL: Individual cognitive stimulation therapy (iCST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COMETS - Compare the Efficacy of Rosuvastatin With Atorvastatin and Placebo in the Treatment of Non-Diabetic, Non-Atheroscleric, Metabolic Syndrome Subjects
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer
Status: COMPLETED
Conditions: Rectal Adenocarcinoma|Stage II Rectal Cancer AJCC v7|Stage III Rectal Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Fluorouracil|DRUG: Leucovorin Calcium|DRUG: Oxaliplatin|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammation-related Alterations in Neurocircuitry: Reversal With Levodopa
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Levodopa+carbidopa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 (Erdafitinib) in Participants With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: JNJ-42756493 (erdafitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dimensional Changes of the Labial Alveolar Ridge After Socket Shield Technique With Computer Guided Root Sectioning
Status: UNKNOWN
Conditions: Edentulous Alveolar Ridge|Dental Trauma
Interventions: PROCEDURE: Socket shield technique with computer guided sectioning of the root
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determinants of Right Heart Remodeling in Patients With CTEPH or PAH
Status: UNKNOWN
Conditions: Chronic Thrombo-embolic Pulmonary Hypertension and Pulmonary Arterial Hypertension
Interventions: RADIATION: magnetic resonance imaging|PROCEDURE: 2D and 3D trans-thoracic echocardiography|OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A SMART Evaluation of an Adaptive Web-based AUD Treatment for Service Members and Their Partners
Status: RECRUITING
Conditions: Alcohol Abuse|Alcohol Use Disorder|Alcohol Drinking|Relations, Interpersonal|Military Family
Interventions: BEHAVIORAL: CRAFT Web-Based Intervention|BEHAVIORAL: Phone-Based CRAFT|BEHAVIORAL: CRAFT Workbook|BEHAVIORAL: Gottman Self-Guided Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Umbilical Cord Clamping Time on Infant Anemia
Status: COMPLETED
Conditions: Third Stage of Labor|Healthy|Umbilical Cord Clamping Time|Infant Conditions
Interventions: PROCEDURE: Delayed Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Study of Frozen Shoulder: Corticosteroid Injection in Joint Versus Wait and See Policy
Status: UNKNOWN
Conditions: Shoulder Capsulitis|Shoulder Adhesive Capsulitis|Frozen Shoulder
Interventions: DRUG: Triamcinolone Acetonide|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Bolus Versus Infusion in Elective Cesarean Section"
Status: RECRUITING
Conditions: Elective Cesarean Section
Interventions: DRUG: Oxytocin bolus or oxytocin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Identification of Multi-modal Bio-markers for Early Diagnosis and Treatment Prediction in Schizophrenia Individuals
Status: UNKNOWN
Conditions: Schizophrenia|Major Depressive Disorder|Anxiety Disorders
Interventions: DRUG: Risperidone|DRUG: Olanzapine|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Thoracic Epidural for Postoperative Ileus
Status: COMPLETED
Conditions: Ileus
Interventions: PROCEDURE: thoracic epidural analgesia|DRUG: iv-PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Nintedanib on the Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Patients With Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Microgynon|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Activity Experiment on Male Prostate Cancer Patients
Status: COMPLETED
Conditions: Cancer Prostate
Interventions: DIAGNOSTIC_TEST: interview|DIAGNOSTIC_TEST: Adult Physical Activity Questionnaire (APAQ)|DEVICE: Activity actigraph|OTHER: Peer training|OTHER: Physical Activity Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tolerability of Pharmaton PHL 00747 in Healthy, Young Female Subjects of Child-bearing Potential
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Pharmaton PHL 00747 soft gelatine capsules|DIETARY_SUPPLEMENT: Pharmaton PHL 00747 film-coated tablets|DIETARY_SUPPLEMENT: Placebo film-coated tablets (fct)|DIETARY_SUPPLEMENT: Placebo soft gelatine capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL|DEVICE: AcrySof Natural IQ (SN60WF) IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Total Extraperitoneal Patch "TEP" Versus Lichtenstein According Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain|Sexual Dysfunction
Interventions: PROCEDURE: Total Extraperitoneal repair (TEP)|PROCEDURE: Lichtenstein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of DFN-15 at 3 Different Doses vs. Comparator and to Determine Dose-proportionality of DFN-15 in Fasting Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DFN-15 Dose 1|DRUG: DFN-15 Dose 2|DRUG: DFN-15 Dose 3|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South Africa
Status: RECRUITING
Conditions: Tuberculosis
Interventions: DIAGNOSTIC_TEST: CAD4TB|DIAGNOSTIC_TEST: POC-CRP|DIAGNOSTIC_TEST: Xpert MTB/RIF Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gemcitabine and Cisplatin Before or After Surgery in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase II Bevacizumab + Tax In Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Status: RECRUITING
Conditions: Postoperative Pain, Acute
Interventions: DRUG: Ketorolac|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Vorinostat in Combination With Gemcitabine and Docetaxel in Advanced Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: Docetaxel|DRUG: Gemcitabine|DRUG: Vorinostat|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders
Interventions: DRUG: volinanserin (M100907)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Passive Mobilization With Place and Hold vs Active Mobilization Therapy After Flexor Tendon Repair
Status: COMPLETED
Conditions: Tendon Injury - Hand
Interventions: PROCEDURE: Active mobilisation|PROCEDURE: Passive mobilisation with place and hold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deficits in Emotion Regulation Skills as a Maintaining Factor in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Affect Regulation Training|BEHAVIORAL: Common Factor Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors|Lung Cancer|Breast Cancer|Head and Neck Squamous Cell Carcinoma|Endometrial Cancer|Melanoma|CRC|Urothelial Carcinoma|Cholangiocarcinoma
Interventions: DRUG: NC318
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: leuprolide acetate|DRUG: goserelin acetate|DRUG: histrelin acetate|DRUG: triptorelin|DRUG: degarelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study for the Effects of Transcranial Magnetic Stimulation on the Brain Using an Electronic Medical Device
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Neurostar TMS Therapy System, NeuroStar XPLOR System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tolerability and Measurability of the Efficacy of Non Pharmaceutical Measures to Prevent Seasonal Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DEVICE: Masks|DEVICE: Masks & hand hygiene|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Head Injuries, Closed|Shock|Shock, Traumatic
Interventions: DRUG: Hypertonic Saline-Dextran Solution|DRUG: Lactated Ringer's Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Deep Cleansing Gel Containing 2% Salicylic Acid, 0.2% Zinc Gluconate and 0.05% Lipohydroxy Acid in the Management of Mild to Moderate Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris on the Face
Interventions: OTHER: Dermocosmetic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Compliance to the Treatment With GRAZAX® Tablets in Patients With Seasonal Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Grass Allergy
Interventions: DEVICE: Electronic compliance device (Memozax®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Mirtazapine for the Dual Tx of Depression and CINV in High-Grade Glioma Pts on TMZ
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma of Brain
Interventions: DRUG: Mirtazapine (Remeron)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Myocardial Contractility After Cardiac Surgery Under an Anterograde or Retrograde Cardioplegia
Status: COMPLETED
Conditions: Heart Arrest
Interventions: PROCEDURE: Antegrade cardioplegia|PROCEDURE: Retrograde cardioplegia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventilation Therapy; Complications|Congenital Heart Disease|Children, Only|Hemodynamic Instability
Interventions: PROCEDURE: PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia
Status: COMPLETED
Conditions: Hypercholesterolemia, Familial|Hyperlipidemia
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Cognitive Therapy for Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BEHAVIORAL: Mindfulness-based cognitive therapy + TAU|OTHER: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emotional Information Processing in Attention Deficit Disorder With or Without Hyperactivity
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Attention Deficit Disorder Without Hyperactivity
Interventions: OTHER: Semantic group|OTHER: Emotional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine to Improve Recovery After Cesarean Delivery - Part 1
Status: COMPLETED
Conditions: Obstetric Pain|Postpartum Depression|Breastfeeding|Pain, Acute|Pain, Chronic|Obstetric Anesthesia Problems|Drug Effect|Opioid Use
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Converting Maintenance Kidney and Liver Transplant Recipients With Abnormal Glucose Metabolism From Tacrolimus to Cyclosporine Micro-emulsion
Status: TERMINATED
Conditions: Tacrolimus-associated Abnormal Glucose Metabolism in Kidney and Liver Transplant Recipients
Interventions: DRUG: cyclosporine micro-emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates?
Status: UNKNOWN
Conditions: Seizures|Traumatic Brain Injury
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra Crave: An Investigation of Ultra-Processed Food
Status: RECRUITING
Conditions: Food Addiction
Interventions: OTHER: Low UP (meals provided)|OTHER: Low UP (self-guided)|OTHER: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: West Philadelphia Controls Asthma
Status: COMPLETED
Conditions: Childhood Asthma|Community Health Workers
Interventions: BEHAVIORAL: Yes We Can Children's Asthma Program|BEHAVIORAL: School-Based Asthma Therapy|BEHAVIORAL: Open Airways for School Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy of Tranexamic Acid in Reducing Blood Loss in Hip Fracture Patients.
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures
Interventions: DRUG: Tranexamic acid|OTHER: Physiologic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CBT for Anxiety Sensitivity vs. Disorder-specific CBT: An RCT
Status: COMPLETED
Conditions: Generalized Anxiety|Stress Disorder, Posttraumatic|Social Anxiety|Major Depression|Panic Disorder
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DexCom Hospital Study-CGM Directed Insulin Delivery
Status: TERMINATED
Conditions: Type 2 Diabetes|Hip Osteoarthritis|Knee Osteoarthritis
Interventions: DEVICE: DexCom G6 continuous glucose monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness of Different Non-pharmacological Methods in Pain Management During Vaccination.
Status: COMPLETED
Conditions: Pain
Interventions: BEHAVIORAL: Comparisons of procedural pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 68Ga-FAPI PET/CT to Detect Ongoing Fibroblast Activity in Post-acute COVID-19
Status: COMPLETED
Conditions: Post-Acute COVID-19|Post-Acute COVID-19 Infection|Post-Acute COVID-19 Syndrome|Pulmonary Fibrosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients
Status: UNKNOWN
Conditions: Sickle Cell Crisis
Interventions: DRUG: Morphine Group|DRUG: Ketamine Group|OTHER: standard IV hydration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical Reasons
Status: COMPLETED
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DRUG: Bimatoprost Ophthalmic Solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insomnia Self-Management in Heart Failure
Status: COMPLETED
Conditions: Cardiac Failure|Heart Failure|Congestive Heart Failure|Heart Failure, Congestive|Sleep Initiation and Maintenance Disorders|Chronic Insomnia|Disorders of Initiating and Maintaining Sleep|Fatigue|Pain|Depressive Symptoms|Sleep Disorders|Anxiety
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy for Insomnia|BEHAVIORAL: Self-Management Education for Heart Failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Stage IV Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: yttrium Y 90 monoclonal antibody MN-14
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Sonodynamic Therapy in Participants With Recurrent High-Grade Glioma
Status: RECRUITING
Conditions: High Grade Glioma
Interventions: COMBINATION_PRODUCT: SONALA-001(ALA) and MR-Guided Focused Ultrasound device (MRgFUS)|DEVICE: MR-Guided Focused Ultrasound device (MRgFUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Multi-Dose Tolerability and Pharmacokinetic Study of Teduglutide
Status: COMPLETED
Conditions: Pharmacokinetics and Safety of Elevated Doses
Interventions: DRUG: teduglutide|DRUG: teduglutide|DRUG: tedguglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis
Status: NOT_YET_RECRUITING
Conditions: Hyperhidrosis|Iontophore
Interventions: OTHER: Iontophoresis with methotrexate|OTHER: Iontophoresis with coal tar ointement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Albuterol in Patients With Facioscapulohumeral Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophy, Facioscapulohumeral
Interventions: DRUG: albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AdVance® vs ARGUS® Sling Procedure in Male With Post Prostatectomy Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: AdVance® sling procedure|PROCEDURE: ARGUS Sling procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Treatment of Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine-dependence
Interventions: DEVICE: rTMS treatment group|DEVICE: sham rTMS treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer Patients
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: Low Dose OXIRI (LD-OXIRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics
Status: WITHDRAWN
Conditions: Tic Disorders
Interventions: BEHAVIORAL: comprehensive behavioral intervention therapy (CBIT)|DRUG: Aripiprazole 5Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Biochemical Evaluation of 1% Metformin in Non-surgical Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Critical Limb Ischemia With G-CSF-mobilized Autologous Peripheral Blood Mononuclear Cells
Status: COMPLETED
Conditions: Critical Limb Ischemia|Atherosclerosis|Ischemic Ulcer|Gangrene
Interventions: BIOLOGICAL: Peripheral blood mononuclear cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking
Status: NOT_YET_RECRUITING
Conditions: Epilepsy; Seizure
Interventions: DEVICE: SeizureWise algorithm|DEVICE: Multi-day Visualizations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome Who Completed Protocol CL0600-004 (NCT00081458)
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: teduglutide 0.05 mg/kg/d|DRUG: teduglutide 0.10 mg/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAL-MPE1 Safety and Tolerability Study
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: HAL-MPE1|DRUG: HAL-MPE1 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: From the Gut to the Strut: Reducing Inflammation for Healthy Muscles
Status: RECRUITING
Conditions: Inflammation|Sarcopenia|Gut Permeability
Interventions: DIETARY_SUPPLEMENT: Miotrof® formula|DIETARY_SUPPLEMENT: Placebo formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Lipolytic Cream in an Overweight and Obesity Treatment
Status: COMPLETED
Conditions: Lipolysis|Overweight and Obesity|Diet Modification|Physical Activity
Interventions: COMBINATION_PRODUCT: Dr.K. Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patients
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Recombinant Human Thyroid Stimulating Hormone for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bone Turnover Markers in Post-Menopausal Women With Osteoporosis Treated With Monthly Boniva (Ibandronate)
Status: COMPLETED
Conditions: Post Menopausal Osteoporosis
Interventions: DRUG: Placebo|DRUG: Vitamin D and calcium supplementation|DRUG: ibandronate [Bonviva/Boniva]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modality Augmentation for Navigation: Intuitive Fusion With Optical Lightweight Device (US/MR)
Status: WITHDRAWN
Conditions: Renal Biopsy or Ablation
Interventions: DEVICE: MR-US Fusion Arm|PROCEDURE: Renal Biopsy or Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation
Status: COMPLETED
Conditions: Head Lice
Interventions: DRUG: Ivermectin Cream|DRUG: vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Investigate If the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed with Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes Mellitus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiome Mediated Effects of Inulin Supplementation on Mineral and Bone Metabolism in Hemodialysis Patients
Status: COMPLETED
Conditions: Bone Diseases, Endocrine|Nutritional and Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency and Changes of Cytokines Expression in Tear After Intense Pulsed Light Treating Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: OPT IPL|DEVICE: Sham OPT IPL|PROCEDURE: MGX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dietary Supplement (Beta-Glucans) in Allergic Patients Undergoing Subcutaneous Immunotherapy.
Status: ACTIVE_NOT_RECRUITING
Conditions: Rhinitis|Allergic Rhinoconjunctivitis|Rhinoconjunctivitis|Controlled Asthma|Uncontrolled Asthma
Interventions: DRUG: Specific immunotherapy (SIT) treatment|DIETARY_SUPPLEMENT: Dietary Supplement: ABB C1|DIETARY_SUPPLEMENT: Mini-tablets with pork extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)
Status: COMPLETED
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Calcumin (Curcumin)|OTHER: Risk Factor Questionnaire|OTHER: Blood samples|OTHER: Biopsies (Sigmoidoscopy)|OTHER: Biopsies (Upper endoscopy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NIH Substudy of AIN457 (Anti-IL-17 Monoclonal Antibody) for Treatment of Moderate to Severe Crohn's Disease
Status: TERMINATED
Conditions: Colitis|Crohn's Disease|Inflammatory Bowel Disease
Interventions: OTHER: Immunologic Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psilocybin-assisted Existential, Attachment and RelationaL (PEARL) Therapy for Patients With Advanced Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Stage IV Solid Tumor Cancer|Stage IV Sarcoma of Bone|Stage IV Lymphoma|Stage IV Melanoma|Endocrine Cancer
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic Study of ARALAST (Human Alpha1- PI)
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: BIOLOGICAL: Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor|BIOLOGICAL: Dose of 60 mg/kg alpha1-proteinase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds
Status: TERMINATED
Conditions: Wounds and Injuries|Wound Healing|Granulation Tissue
Interventions: DEVICE: Negative Pressure Therapy w/ instillation and dwell (NPWTi-d)|BIOLOGICAL: Collagenase Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Tailored Messages to Address Parental Questions About HPV Vaccination
Status: COMPLETED
Conditions: Human Papilloma Virus Vaccines|Attitude to Health
Interventions: BEHAVIORAL: Top Concern Tailored Intervention|BEHAVIORAL: All Concerns Tailored Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gingival Displacement With RACESTYPTINE Solution and RACEGEL: a Prospective, Comparative Randomized Clinical Trial.
Status: COMPLETED
Conditions: Gingival Retraction Techniques
Interventions: DEVICE: RACESTYPTINE Solution with cord|DEVICE: RACEGEL with cord|DEVICE: RACEGEL without cord
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Residual Allergenicity of Ragweed Pollen Allergoid With Monophosphoryl Lipid A (MPL) Using Skin Prick Testing
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Ragweed MATA MPL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Canakinumab|DRUG: Colchicine|DRUG: Allopurinol|DRUG: Placebo Matching Canakinumab|DRUG: Placebo Matching Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Ambulatory Cardiac Monitoring for Recurrent Atrial Fibrillation After Sepsis
Status: UNKNOWN
Conditions: Atrial Fibrillation|Sepsis|Infections|Cardiac Arrhythmia
Interventions: DEVICE: Zio 14-day cardiac patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BB-10901 in Treating Patients With Relapsed or Refractory Solid Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Merkel Cell Carcinoma|SCLC
Interventions: DRUG: BB-10901
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S Protein and COVID-19: a Monocentric Prospective Study
Status: RECRUITING
Conditions: COVID-19
Interventions: PROCEDURE: Hematolgy and Chemistry analysis|PROCEDURE: Real Time PCR|PROCEDURE: PROS assay COVID+|PROCEDURE: Sflt1 assay COVID+|PROCEDURE: PROS assay CONTROL|PROCEDURE: Sflt1 assay CONTROL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Respiratory Virus Hospitalization Study (FLU 003 Plus)
Status: RECRUITING
Conditions: Influenza|Novel Respiratory Virus-1 Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV)|Novel Respiratory Virus-2 Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pharmacokinetic Study Comparing the 14028 Injection and TRULICITY® in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BIOLOGICAL: 14028 injection|BIOLOGICAL: dulaglutide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25306)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: bitopertin [RO4917838]|DRUG: bitopertin [RO4917838]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, PK, and PD of PB2452 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PB2452 Infusion|DRUG: Placebo - Sodium Chloride|DRUG: Ticagrelor Oral Tablet - Pre-Treatment|DRUG: Ticagrelor Oral Tablet - Pre-Treatment and Post-Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zeiss RESIGHT Disposable Lenses Evaluation Study
Status: COMPLETED
Conditions: Retinal Detachment|Macular Pucker|Macular Holes|Vitreomacular Traction
Interventions: DEVICE: ZEISS disposable
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuropeptide Treatment for Hot Flushes During the Menopause
Status: COMPLETED
Conditions: Menopausal Flushing
Interventions: DRUG: NK3R antagonist - AZD4901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amplitude Vascular Systems (AVS) Lithotripsy POWER PAD 2 Trial
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease (PAD)
Interventions: DEVICE: Pulse Intravascular Lithotripsy (Pulse IVL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aerosal® in the Treatment of Sub-Obstructive Adenotonsillar Hypertrophy and Related Diseases
Status: TERMINATED
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Halotherapy|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Combination Chemotherapy in Treating Patients With Previously Untreated Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: capecitabine|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Lucanix™ in Patients With Stages II-IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasm|Carcinoma, Bronchogenic
Interventions: BIOLOGICAL: Lucanix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Administration of Oral Carbohydrate Drink, Neutrophil/Lymphocyte Ratio and Postoperative Complications
Status: COMPLETED
Conditions: Neutrophil|Lymphocyte|Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: preoperative nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of the PXL Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Position
Status: COMPLETED
Conditions: Keratoconus, Unstable|Ectasia Corneal|Bacterial Keratitis
Interventions: COMBINATION_PRODUCT: PXL 330 Platinum device/Riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Mechanism of Action of Ruxolitinib Cream in Subjects With Vitiligo (TRuE-V MOA)
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Olanzapine and Lipid Response
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Olanzapine 10 milligram|DRUG: Bromocriptine 5 milligram|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Rehabilitation Effort at Home in Patients With Head and Neck Tumor Treated With Curative Intent
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: custom work endurance|BEHAVIORAL: dietary management adapted to the nutritional status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nitric Oxide Generating Gel Dressing in Patients With Superficial Partial Thickness Wounds
Status: TERMINATED
Conditions: Superficial Partial Thickness Burn|Skin Graft; Complications
Interventions: DEVICE: NOx dressing|DEVICE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mp-MRI in the Diagnosis of Liver Fibrosis After Liver Transplantation
Status: UNKNOWN
Conditions: Liver Fibrosis After Liver Transplantation|Multiparameter Magnetic Resonance Imaging
Interventions: DIAGNOSTIC_TEST: Gadopentetate Dimeglumine Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extended Varenicline Treatment for Smoking Among Cancer Patients
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo|BEHAVIORAL: Smoking Cessation Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: oxaliplatin|PROCEDURE: management of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Standard dose, low flux hemodialysis|DEVICE: Standard dose, high flux hemodialysis|DEVICE: High dose, low flux hemodialysis|DEVICE: High dose, high flux hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic and Pharmacodynamic Study to Determine Blood Levels of JNJ-28431754 (Canagliflozin) in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Canagliflozin 50 mg|DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxal & Cisplatin vs LDFRT + Docetaxal & Cisplatin in Locally Advanced NPC
Status: UNKNOWN
Conditions: Nasopharyngeal Cancer
Interventions: COMBINATION_PRODUCT: Chemo + Low dose RT|DRUG: Chemo alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT