pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Pharmacokinetics and Efficacy of CT-707, Toripalimab and Gemcitabine in Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: CT-707|DRUG: Toripalimab|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation Combined With Sintilimab Plus Lenvatinib in 1L Treatment of Advanced ICC (CASTLE-ICC-Chemo-free)
Status: RECRUITING
Conditions: Advanced Intrahepatic Cholangiocarcinoma
Interventions: PROCEDURE: Cryoablation|DRUG: Sintilimab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 24-week Study of Fluticasone Furoate/Vilanterol Inhalation Powder in Subjects of Asian Ancestry With COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone furoate/vilanterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With VRC01 and 10-1074 in HIV-Infected Individuals Undergoing Sequential Treatment Interruptions
Status: TERMINATED
Conditions: HIV
Interventions: BIOLOGICAL: VRC-HIVMAB060-00-AB (VRC01)|BIOLOGICAL: 10-1074|BIOLOGICAL: Normal Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Educational Training Influence in Patients With PAH(Pulmonary Artery Hypertension) on Inhaled Ventavis Treatment Adherence Evaluated Trough INSIGHT System
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: OTHER: Iloprost (Ventavis inhaled, BAYQ6256)|OTHER: Iloprost (Ventavis inhaled, BAYQ6256)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pitolisant to Assess Weekly Frequency of Cataplexy Attacks and EDS in Narcoleptic Patients (HARMONY CTP)
Status: COMPLETED
Conditions: Narcolepsy With Cataplexy|Excessive Daytime Sleepiness
Interventions: DRUG: Pitolisant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Combined Design Nance/Transpalatal Arch Appliance in Maintaining Arch Dimensions After Premature Extraction of Primary Molars
Status: COMPLETED
Conditions: Space Maintenance
Interventions: DEVICE: Nance/Transpalatal arch space maintainer|DEVICE: Nance space maintainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Infection
Interventions: DRUG: Tenofovir Disoproxil Fumarate (TDF) 300 mg + Lamivudine (3TC) 300 mg + Efavirenz (EFV) 600 mg|DRUG: Abacavir (ABC) 600 mg + Lamivudine (3TC) 300 mg + Efavirenz (EFV) 600 mg|DRUG: Zidovudine (AZT) 300 mg + Lamivudine (3TC) 150 mg twice daily + Efavirenz (EFV) 600 mg once daily
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Immune Response in Pediatric Kidney Transplant Recipients Treated With Daclizumab (Zenapax)
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: BIOLOGICAL: DT|DRUG: Daclizumab|BIOLOGICAL: KLH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy Combined With Adjuvant Chemotherapy Treated Advanced Cervical Cancer
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms|Chemoradiotherapy|Adjuvant Chemotherapy
Interventions: DRUG: paclitaxel combined with platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Bortezomib in Patients With Advanced Malignancy
Status: COMPLETED
Conditions: Advanced Malignancy|Lymphoma|Myeloma|Solid Tumors
Interventions: DRUG: Bevacizumab|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Low Molecular Weight Heparin (Tinzaparin) to Treat Blood Clots in Patients With Kidney Failure
Status: TERMINATED
Conditions: Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Residual Gastric Volume After the Ingestion of a Beverage Containing Carbohydrates Plus Whey Protein
Status: COMPLETED
Conditions: Peptic Ulcer|Gastritis
Interventions: DIETARY_SUPPLEMENT: Carbohydrate plus whey protein enriched drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of the Efficacy and Safety of SCH 619734 in Subjects With Chronic Cough From an Unknown Cause (Study P04888)
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: SCH 619734|DRUG: Placebo Dose 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Antihistamines on Ureteral Stent-Related Symptoms
Status: COMPLETED
Conditions: Nephrolithiasis
Interventions: DRUG: Fexofenadine Hcl 180Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Influence of Immobilisation, Stretching and Activity on Morphological and Mechanical Properties of Spastic Muscle
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Palsy, Spastic
Interventions: OTHER: Stretching through immobilisation (IG)|OTHER: Stretching through immobilisation and activity (IAG)|OTHER: Control Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer
Status: COMPLETED
Conditions: Neurotoxicity|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: lamotrigine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The CALIBER Study Randomized Controlled Trial of LINX Versus Double-Dose Proton Pump Inhibitor Therapy for Reflux Disease
Status: COMPLETED
Conditions: GERD Gastroesophageal Reflux Disease
Interventions: DRUG: Omeprazole|DEVICE: LINX Reflux Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Antithrombotic Care in Patients With AtriaL fibrillatiON and Coronary stEnt (OAC-ALONE) Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Coronary Artery Disease
Interventions: DRUG: OAC alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibroids in Women of Reproductive Age and Women Pregnancy
Status: COMPLETED
Conditions: Fibroids
Interventions: DRUG: Dydrogesterone M ( case 1 )|DRUG: Dydrogesterone M ( case 2 )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP)
Status: NOT_YET_RECRUITING
Conditions: Diabetic Peripheral Neuropathic Pain
Interventions: DRUG: Medical Cannabis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Frequency of Adverse Events in Pediatric Patients Receiving Sedation for Magnetic Resonance Imaging
Status: RECRUITING
Conditions: Sedation|Pediatric Anesthesia|Magnetic Resonance Imaging|Adverse Effect
Interventions: OTHER: Pediatric patients who received sedation for magnetic resonance imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Twin Block Appliance in Incremental Versus Maximum Bite Advancement in Skeletal Class II
Status: UNKNOWN
Conditions: Mandibular Retrognathism|Mandibular Hypoplasia
Interventions: DEVICE: Modified Twin Block|DEVICE: Twin Block Appliance set to maximum bite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Incentives to Improve Parolee Participation and Attendance in Community Treatment
Status: COMPLETED
Conditions: Substance Abuse|HIV Infections
Interventions: BEHAVIORAL: Contingency management: voucher/monetary incentives for treatment attendance|BEHAVIORAL: Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Efficacy of AZD2281 in Platinum Sensitive Relapsed Serous Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: AZD2281|DRUG: matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MT10109L in the Treatment of Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines
Interventions: DRUG: MT10109L|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diltiazem to Improve Coronary Microvascular Dysfunction: a Randomized Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Microvascular Angina|Coronary Vasospasm|Microvascular Ischemia of Myocardium
Interventions: DRUG: Diltiazem Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR)
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Fluticasone 250mcg/Formoterol 12mcg/Glycopyrronium 25mcg|DRUG: Comparator - Trimbow®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of the T3 Short Dental Implant System
Status: ACTIVE_NOT_RECRUITING
Conditions: Edentulous Jaw
Interventions: DEVICE: T3 short and restoration (prosthesis)|DEVICE: T3 standard length and restoration (prosthesis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A1 Versus A2® Milk on the Gastrointestinal Physiology, Symptoms and Cognitive Behaviour for the Preschool Children
Status: COMPLETED
Conditions: Gut Inflammation
Interventions: DIETARY_SUPPLEMENT: Oral consumption of milk A1 in study phase 1|DIETARY_SUPPLEMENT: Oral consumption of milk A2 in study phase 1|DIETARY_SUPPLEMENT: Oral consumption of milk A1 in study phase 2|DIETARY_SUPPLEMENT: Oral consumption of milk A2 in study phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Randomized Study on the Effects of Valgus Knee Brace for Knee Osteoarthritis in Chinese Patients
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Valgus knee brace (Medex K39-OA Corrector)|OTHER: Physiotherapy and oral analgesic (diclofenac and panadol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Address Food Insecurity in Patients With Hypertension (SMART-FI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Resource information Supplemental Nutrition Assistance Program (SNAP)|BEHAVIORAL: community health worker (CHW)|BEHAVIORAL: medically tailored meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Phototherapy in the Treatment of Loss of Smell Post Acute Infection of Coronavirus 19
Status: UNKNOWN
Conditions: Smell Disorders
Interventions: COMBINATION_PRODUCT: Phototherapy|COMBINATION_PRODUCT: OT+Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Fatigue and Activity Management in Work (FAME-W) for Individuals With Inflammatory Arthritis
Status: UNKNOWN
Conditions: Inflammatory Arthritis
Interventions: BEHAVIORAL: FAME-W self-management intervention|BEHAVIORAL: FAME-W Handbook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SuperB Trial: SUrgical Versus PERcutaneous Bypass
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: PROCEDURE: Heparin-bonded ePTFE endoluminal fem-pop bypass|PROCEDURE: Surgical femoro-popliteal bypass.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Crowns Versus Prefabricated Crowns on Primary Teeth
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Caries in Children
Interventions: PROCEDURE: Digital crowns|PROCEDURE: zirconia crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: DMID 21-0041; Influenza CVD 59000
Status: RECRUITING
Conditions: Influenza
Interventions: BEHAVIORAL: Personal Protective Equipment (PPE) - Under High Air Hygiene|BEHAVIORAL: No Intervention - Under High Air Hygiene|BEHAVIORAL: Personal Protective Equipment (PPE) - Under Low Air Hygiene|BEHAVIORAL: No Intervention - Under Low Air Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Satraplatin in Hormone Refractory Prostate Cancer Patients Previously Treated With One Cytotoxic Chemotherapy Regimen
Status: COMPLETED
Conditions: Prostate Cancer|Hormone Refractory Prostate Cancer
Interventions: DRUG: Satraplatin|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Axillary Management After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasms|Breast Cancer Female
Interventions: PROCEDURE: Axillary sentinal lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Calculus Bovis Sativus (CBS) for Adult Encephalitis (CBSinEncephalitis)
Status: NOT_YET_RECRUITING
Conditions: Encephalitis|Encephalitis, Viral|Autoimmune Encephalitis Caused by N-Methyl D-Aspartate Receptor Antibody|Autoimmune Encephalitis
Interventions: DRUG: Calculus bovis sativus (CBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Steroids During Pneumocystis Infection Among Non HIV Immunocompromised Patients
Status: UNKNOWN
Conditions: Pneumocystis|Steroids|Immunocompromised Patient|Hematologic Neoplasms|Immunosuppressive Agents|Neoplasms
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Head to Head Study Against Sevelamer Hydrochloride
Status: COMPLETED
Conditions: Chronic Kidney Disease, Stage 5
Interventions: DRUG: Fosrenol (Lanthanum Carbonate)|DRUG: Sevelamer hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: BIBW 2992|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gluten-free Diet on Parkinsonism
Status: RECRUITING
Conditions: Parkinson Disease|Multiple System Atrophy|Non-celiac Gluten Sensitivity
Interventions: OTHER: gluten-free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Stem Cells in Large Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Intracoronary infusion of autologous bone-marrow derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TroVax Renal Immunotherapy Survival Trial
Status: COMPLETED
Conditions: Clear Cell Renal Carcinoma
Interventions: BIOLOGICAL: Trovax|BIOLOGICAL: Placebo|BIOLOGICAL: Standard of care therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing of the Pharmacokinetic, Safety and Immunogenicity of HS-20090-2 Injection and Prolia® in Healthy Adults
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: HS-20090-2|DRUG: Prolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Choice of Intraoperative Opioid on Postoperative Pain
Status: COMPLETED
Conditions: Pain, Postoperative|Chronic Pain
Interventions: DRUG: Methadone|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care Planning in Improving the Quality of Life in Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Cancer Survivor
Interventions: OTHER: educational intervention|OTHER: counseling intervention|PROCEDURE: standard follow-up care|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Deep Transcranial Magnetic Stimulation After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Deep TMS (Transcranial magnetic stimulation)|DEVICE: Brainsway Deep TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis|Psoriasis
Interventions: BIOLOGICAL: M923|BIOLOGICAL: Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Preterm Infants Who Are Placed on Their Back or Stomach in the Immediate Postextubation Period
Status: UNKNOWN
Conditions: Pregnancy Preterm
Interventions: OTHER: Prone position|OTHER: Supine position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS)
Status: COMPLETED
Conditions: Confirmed Genetic Diagnosis of Prader-Willi Syndrome
Interventions: DRUG: Tesofensine/Metoprolol|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Gestational Diabetes Mellitus With Lifestyle Intervention Among Women of Advanced Maternal Age.
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus
Interventions: BEHAVIORAL: mobile-based combining with hospital-based lifestyle interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Macrolide Antibiotics on Airway Inflammation in People With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Azithromycin|DRUG: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UMIT-1 Trial Favipiravir & Ribavirin for the Treatment of CCHF
Status: RECRUITING
Conditions: CCHF
Interventions: DRUG: Favipiravir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cryotherapy on Primary Dysmenorrhoea
Status: COMPLETED
Conditions: Dysmenorrhea Primary
Interventions: DEVICE: Cryotherapy|OTHER: core stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Blinded, Controlled Clinical Trial of Surgically Facilitated Orthodontic Treatment
Status: WITHDRAWN
Conditions: Orthodontic Malocclusion
Interventions: PROCEDURE: Surgically facilitated Orthodontic treatment|PROCEDURE: Conventional orthodontic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The LEADLESS II IDE Study for the Aveir VR Leadless Pacemaker System
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Rhythm Disorder|Bradycardia
Interventions: DEVICE: Aveir VR Leadless Pacemaker System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture.
Status: COMPLETED
Conditions: Acute Pain Due to Trauma
Interventions: PROCEDURE: lidocaine with epinephrine|PROCEDURE: normal saline|PROCEDURE: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary
Interventions: DEVICE: Flexible Bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Efficacy and Safety Study of Decitabine (DACOGEN) Plus Talacotuzumab (JNJ-56022473; Anti CD123) Versus Decitabine (DACOGEN) Alone in Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: Decitabine 20 mg/m^2|DRUG: Talacotuzumab 9 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patients
Status: COMPLETED
Conditions: Kidney Transplant; Complications|Toxicity|Drug Toxicity|Neurotoxicity
Interventions: DRUG: Envarsus|DRUG: IR Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: lintuzumab|DRUG: cytarabine|DRUG: etoposide|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Enuresis|Obstructive Sleep Apnea|Sleep Disordered Breathing
Interventions: DEVICE: Bed Alarm|DRUG: Nasonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise, Hypoxia and CPC in TBI Patients
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: OTHER: cognitive activities|OTHER: Exercise program|DEVICE: Muscle electro-stimulation|OTHER: Intermittent hypobaric hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Electrical Coupling Information From The Rhythmia HDx System And DirectSense Technology In Subjects With Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: Ablation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Four Methods of Ovarian Stimulation in Patients With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Ovarian Hyperstimulation Syndrome
Interventions: OTHER: Minimal ovarian stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy Interferon-Gamma 1b in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Interferon-gamma 1b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
Status: COMPLETED
Conditions: Aggressive Non-Hodgkin Lymphoma|Blasts Under 5 Percent of Bone Marrow Nucleated Cells|Chronic Lymphocytic Leukemia|Loss of Chromosome 17p|Myelodysplastic/Myeloproliferative Neoplasm|Non-Hodgkin Lymphoma|Prolymphocytic Leukemia|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Acute Myeloid Leukemia|Recurrent Aggressive Adult Non-Hodgkin Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Hodgkin Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Recurrent Small Lymphocytic Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Atorvastatin Calcium|DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Optical Coherence Tomography Following Paclitaxel Eluting Stent Implantation in Multivessel Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Taxus Libertè™ paclitaxel drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of BI 201335 Capsule Versus Three Different Oral Solutions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 (Reference)|DRUG: BI 201335 (Test)|DRUG: BI 201335 (Test)|DRUG: BI 201335 (Test)|DRUG: BI 201335 (Reference)|DRUG: BI 201335 (Test)|DRUG: BI 201335 (Test)|DRUG: BI 201335 (Test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Therapy for Recurrent Clostridium Difficile Infection
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Fecal Microbiota|DRUG: vancomycin|DRUG: Loperamide|DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagus|Recurrent Esophageal Cancer|Stage IV Esophageal Cancer
Interventions: DRUG: triapine|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus
Status: TERMINATED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation Of An Advanced Borderless Dressing
Status: COMPLETED
Conditions: Pressure Ulcer|Leg Ulcer|Diabetic Foot Ulcer
Interventions: DEVICE: ALLEVYN Life Non-Bordered|DEVICE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pentoxifylline on Prognosis of Coronavirus Disease 2019 (COVID- 19) Infection
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection|Cytokine Storm
Interventions: DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Safety and Efficacy of CD7 CAR-T Cell in Patients With Relapsed/Refractory Acute Leukemia
Status: RECRUITING
Conditions: Acute-Leukemia
Interventions: BIOLOGICAL: CD7 CAR-T cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SyB L-0501 in Combination With Rituximab to Treat Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Lymphoma, Large Cell|Diffuse, Mantle Cell Lymphoma, Lymphoma|Follicular Lymphoma|Large B-Cell, Diffuse
Interventions: DRUG: SyB L-0501|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety & Effectiveness of the Bausch & Lomb AKREOS® TL Intraocular Lens
Status: COMPLETED
Conditions: Cataract|Aphakia
Interventions: DEVICE: The Bausch & Lomb Akreos TL IOL (MI60) posterior chamber IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise for People With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Formally Directed Group (Exercise Group)|OTHER: Self-Directed Group (Control Group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paroxetine Safety and Efficacy in Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate|DRUG: Paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunization With NY-ESO-1 Protein Combined With CpG 7909 in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: NY-ESO-1 protein/CpG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Home Program Using Multimodal Sensory Feedback for People With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: exercise+multi-modal sensory feedback (MMSF)|BEHAVIORAL: Exercise only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Photobiomodulation & Ketogenic Diet for Treatment of Mid-periphery Retinal Disorders for Alzheimer's Disease Prevention
Status: UNKNOWN
Conditions: Diabetic Retinopathy (DR)|Age-related Macular Degeneration (AMD)|Mid-peripheral Drusen Formation|Diabetic Macular Edema (DME)
Interventions: BEHAVIORAL: Photobiomodulation|BEHAVIORAL: Ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dentifrice Formulations to Remineralize Enamel and Dentine Subsurface Lesions in a Double-Blind In-Situ Clinical Trial
Status: COMPLETED
Conditions: Caries
Interventions: DRUG: 0 ppm Fluoride Dentifrice 1|DRUG: 1100 ppm NaF Fluoride Dentifrice|DRUG: 1500 ppm NaMFP Fluoride Dentifrice|DRUG: 0 ppm Fluoride Dentifrice 2|DRUG: 0 ppm Fluoride Dentifrice 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Liposomal Curcumin in Healthy Volunteers
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: Liposomal Curcumin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR
Status: COMPLETED
Conditions: SARS-CoV Infection|Polymerase Chain Reaction|Laboratory Testing
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug-drug Interaction Study Between EDP-305, Intraconazole and Rifampin in Healthy Volunteers
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: intraconazole|DRUG: Rifampin|DRUG: EDP 305
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Low Intensity Exercise and Protein Intake on Skeletal Muscle Protein Synthesis in Elderly
Status: COMPLETED
Conditions: Skeletal Muscle Protein Synthesis in Elderly|Protein Kinetics|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Protein|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: selenomethionine|DRUG: finasteride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mannitol (Aridol) and Methacholine (Provocholine) Responsiveness
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Methacholine (Provocholine)|DRUG: Mannitol (Aridol)|DRUG: Methacholine (Provocholine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Alternate Therapies on Intraocular Pressure in Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: OTHER: Alternate Nostril Breathing|DEVICE: Foot Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delivery SSO2 Therapy for 60 Min in Anterior MI Patients With PCI ≤ 6 Hours of Symptoms Onset Compared to Standard.
Status: RECRUITING
Conditions: Acute Myocardial Infarction|STEMI
Interventions: DEVICE: TherOx DownStream System|DEVICE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Effectiveness of Sodium Hyaluronate When Used for the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Dermal Filler|Hyaluronic Acid|Lidocaine|Nasolabial Fold
Interventions: DEVICE: HA+Lidocaine|DEVICE: HA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genotyping Influences Outcome of Coronary Artery Stenting
Status: COMPLETED
Conditions: Myocardial Ischemia|CLOPIDOGREL, POOR METABOLISM of (Disorder)
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Health Promotion Program for the Caregivers of Attention Deficit/Hyperactivity Disorders Children
Status: UNKNOWN
Conditions: ADHD|Caregiver Stress Syndrome
Interventions: BEHAVIORAL: Health Promotion Program|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Low-dose Naltrexone in Combination With a Range of Smoked Marijuana
Status: COMPLETED
Conditions: Marijuana Smoking
Interventions: DRUG: Inactive Marijuana (0% THC)|DRUG: Active Marijuana (5.5% THC)|DRUG: Active Marijuana (6.2% THC)|DRUG: Naltrexone|DRUG: Placebo naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of 0.1% and 0.03% Tacrolimus Ointment Administered in Adults With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Ranging Study to Compare Doravirine (MK-1439) Plus TRUVADA® Versus Efavirenz Plus TRUVADA® in Human Immunodeficiency Virus (HIV)-1 Infected Participants (MK-1439-007)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Doravirine|DRUG: Efavirenz|DRUG: TRUVADA®|DRUG: Placebo for Doravirine|DRUG: Placebo for Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukine 6 (IL6) Assay for Predicting Failure of Spontaneous Breathing in Patients With COVID-19 Acute Respiratory Distress Syndrome
Status: TERMINATED
Conditions: COVID-19 Acute Respiratory Distress Syndrome
Interventions: BIOLOGICAL: IL6 assessment|BIOLOGICAL: CRP and PCT assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Sensi-IP Toothpaste in the Treatment of Dentinal Hypersensitivity Compared to a Sodium Fluoride Toothpaste
Status: COMPLETED
Conditions: Dentinal Hypersensitivity
Interventions: DEVICE: Sensi-IP toothpaste|DEVICE: Sodium Fluoride Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tamarindus Indica Fruit Juice in Optimizing Cardiometabolic Health of Patients Living With HIV
Status: COMPLETED
Conditions: Cardiometabolic Syndrome|Dyslipidemias|Hypertension
Interventions: DIETARY_SUPPLEMENT: Tamarindus indica fruit juice_A|DIETARY_SUPPLEMENT: Tamarindus indica fruit juice_B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COcoa Supplement and Multivitamin Outcomes Study
Status: UNKNOWN
Conditions: Cardiovascular Disease|Cancer
Interventions: DIETARY_SUPPLEMENT: Cocoa extract|DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Cocoa extract placebo|DIETARY_SUPPLEMENT: Multivitamin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pharmacokinetics|Solid Tumor|Carcinoma, Non-Small-Cell Lung|Triple Negative Breast Neoplasms
Interventions: DRUG: Boserolimab|BIOLOGICAL: Pembrolizumab|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real-World Evaluation of Eko Algorithms in a Point of Care Setting
Status: RECRUITING
Conditions: Murmur, Heart|Innocent Murmurs|Heart Murmurs|Pathologic Murmur|Atrial Fibrillation
Interventions: DEVICE: Use of Eko CORE and Eko CORE 500 electronic stethoscope
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial of Pulsed Electric Field Therapy in Patients With Late-stage Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: NSCLC
Interventions: DEVICE: PEF|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: KRP-104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Versus Cilostazol in Large-vessel Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Clopidogrel tablet|DRUG: Cilostazol 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Transplantation for Non-Resectable Colorectal Liver Metastasis
Status: RECRUITING
Conditions: Liver Metastasis Colon Cancer|Colorectal Cancer
Interventions: PROCEDURE: Liver Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osseointegration of Hydroxyapatite-coated Femoral Stems in Femoral Neck Fractures Over 80 Years
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Hemiarthroplasty with hydroaxyapatite coated stem
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Left Atrial Appendage Occlusion in Patients With Non-valvular Atrial Fibrillation From Shanghai
Status: UNKNOWN
Conditions: Atrial Fibrillation|Left Atrial Appendage Occlusion
Interventions: DEVICE: left atrial appendage occlusion devices
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Trial of Combination Therapy With Celecoxib and Taxotere for the Treatment of Stage D3 Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Taxotere|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
Status: RECRUITING
Conditions: Infant, Extremely Premature|Obstetric Labor, Premature|Premature Birth|Intensive Care, Neonatal|Intensive Care Units, Neonatal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p