pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics
Status: NOT_YET_RECRUITING
Conditions: Compartment Syndrome Nontraumatic Lower Extremity
Interventions: DEVICE: NIRS monitoring|DEVICE: Laser Doppler flowmetry|OTHER: Inflammatory and Oxidative stress biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Efficacy, Safety and Tolerability of DFD-04
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: DFD-04 Ointment|OTHER: Placebo Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: My Healthy Diary - An Electronic Diary for Remote Migraine Monitoring
Status: UNKNOWN
Conditions: Episodic Migraine|Migraine Disorders
Interventions: DEVICE: Electronic Headache Diary|DEVICE: Paper Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Injured Submucosal Arteries After CSP for 10-19 mm Nonpedunculated Colorectal Polyps.
Status: RECRUITING
Conditions: Colonic Polyp
Interventions: PROCEDURE: Experimental CSP|PROCEDURE: Active Comparator HS-EMR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Solar Radiation on Human Function and Cognition
Status: COMPLETED
Conditions: Heat Stress|Heat Strain
Interventions: OTHER: Radiation and warm environment|OTHER: Warm environment|RADIATION: Neutral environment with radiation|OTHER: Neutral environment without radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Cannabidiol in Sanfilippo Syndrome
Status: NOT_YET_RECRUITING
Conditions: Sanfilippo Syndrome|Mucopolysaccharidosis III
Interventions: DRUG: Epidiolex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra Mini Percutaneous Nephrolithotomy VS Stented Extracorporeal Shock Wave Lithotripsy for Stone Management
Status: COMPLETED
Conditions: Renal Stone
Interventions: PROCEDURE: Ultra-Mini-PCNL|PROCEDURE: Stented SWL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response
Status: TERMINATED
Conditions: Knee Pain|Hip Pain|Ankle Pain|Lumbopelvic Pain
Interventions: OTHER: lumbosacral joint manipulation|OTHER: lumbar passive range of motion|OTHER: No active intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study
Status: COMPLETED
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: DRUG: Abemaciclib|DRUG: Anastrozole|DRUG: Fulvestrant|DRUG: Letrozole|DRUG: Palbociclib|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study to Study the Effect of AZD1981 on Warfarin
Status: COMPLETED
Conditions: Pharmakokinetic
Interventions: DRUG: AZD1981|DRUG: Warfarin|DRUG: AZD1981
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: Rituximab|DRUG: Obinutuzumab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity as Intervention Against Age-related Loss of Muscle Mass and Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Muscle Weakness|Muscle Loss|Sarcopenia|Physical Activity
Interventions: OTHER: Heavy resistance training|OTHER: Moderate intensity training|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CH-4051|DRUG: Methotrexate (MTX)|DRUG: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Model-Based PMR Training on Anxiety and Blood Sugar Levels to Women With Gestational Diabetes
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy|Anxiety in Pregnancy
Interventions: BEHAVIORAL: Diet therapy, Progressive Muscle Relaxation training, Progressive Muscle Relaxation group|BEHAVIORAL: The group who received diet therapy and practiced their daily activities.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Treatment Responses of Early Syphilis to Benzathine Penicillin G With or Without Doxycycline
Status: NOT_YET_RECRUITING
Conditions: Early Syphilis, Latent, Serological Relapse After Treatment
Interventions: DRUG: Benzathine Penicillin G|DRUG: Doxycycline Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Diabetes Self-Management Education Program Based on Behavioural Change Theory
Status: COMPLETED
Conditions: Health Behavior|Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Diabetes Self-Management Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Sarcoma|Small Intestine Cancer
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Nelfinavir mesylate|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Needle Hand Acupuncture for MSK Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Acupuncture|Pain|Range of Motion
Interventions: PROCEDURE: One Needle Hand Acupuncture with Movement|PROCEDURE: One Needle Hand Acupuncture without Movement|PROCEDURE: Control Acupuncture with Movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GCF Annexin-A1, Carbonic Anhydrase-1, and Elongation Factor-1 Gamma Levels in Periodontitis
Status: COMPLETED
Conditions: Periodontitis|Periodontal Inflammation
Interventions: OTHER: Peirodontal clinical measurements and gingival crevicular fluid sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Behavioral and Affective Skills in Coping (BASIC) Open Trial
Status: COMPLETED
Conditions: Anxiety Disorders|Depressive Disorders|Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Behavioral and Affective Skills in Coping (BASIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Focused Ultrasound Ablation Virus Myomectomy to Treat Uterine Fibroids
Status: UNKNOWN
Conditions: Uterine Fibroid
Interventions: PROCEDURE: High intensity focused ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ketorolac / Pitofenone / Fenpiverinium for the Treatment of Patients With Pain After Surgical Abdominal and Pelvic Operations
Status: COMPLETED
Conditions: Postsurgical Pain
Interventions: DRUG: Ketorolac tromethamine, solution for injection then Neospastil, film-coated tablets|DRUG: Ketorolac tromethamine, solution for injection then Ketorolac tromethamine, coated tablets|DRUG: Neospastil, solution for injection then Neospastil, film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of N-Acetyl-Cysteine in Bipolar Disorder and Tobacco Use Disorder
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: DIETARY_SUPPLEMENT: N-Acetyl-Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label, Double-blind Discontinuation Study of Quetiapine Extended Release(XR)
Status: TERMINATED
Conditions: Social Anxiety Disorder
Interventions: DRUG: Quetiapine XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Immunogenicity of mRNA COVID-19 Variant-containing Vaccine Formulations in Adults to Prevent COVID-19
Status: NOT_YET_RECRUITING
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273 Variant-containing Formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: AR01|DRUG: Glycerin ear drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Riliprubart Against the Usual Treatment of Intravenous Immunoglobulin (IVIg) in People With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyneuropathy
Interventions: DRUG: riliprubart|DRUG: Placebo|DRUG: riliprubart|DRUG: Placebo|DRUG: IVIg|DRUG: Placebo|DRUG: IVIg premedication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Z-Drugs for Sleep Disorders in Alzheimer's Disease
Status: COMPLETED
Conditions: Sleep|Sleep Disorders|Insomnia|Alzheimer's Disease
Interventions: DRUG: Zolpidem|DRUG: Zoplicone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Pravastatin sodium|DRUG: Simvastatin|DRUG: Atorvastatin calcium|DRUG: Ritonavir|DRUG: Nelfinavir mesylate|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupressure for Fatigue and Low Back Pain
Status: COMPLETED
Conditions: Fatigue|Chronic Low Back Pain
Interventions: BEHAVIORAL: Relaxation acupressure|BEHAVIORAL: Stimulating acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nitrate and Brain Insulin-Sensitivity
Status: COMPLETED
Conditions: Nitrate|Brain Insulin-sensitivity|Vascular Function
Interventions: DIETARY_SUPPLEMENT: Potassium nitrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Allogeneic Blood Stem Cell Transplantation for Patients With Life-Threatening Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Hematopoietic Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testosterone Replacement for Fatigue in Male Hypogonadic Advanced Cancer Patients
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HX575 Epoetin Alfa Subcutaneously (s.c.) in Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: HX575 epoetin alfa (Sandoz)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Low-Dose Naltrexone for Lichen Planopilaris and Frontal Fibrosing Alopecia
Status: COMPLETED
Conditions: Lichen Planopilaris|Frontal Fibrosing Alopecia
Interventions: DRUG: Low-Dose Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio
Status: COMPLETED
Conditions: Procedural Sedation and Analgesia
Interventions: DRUG: Procedural sedation with ketofol in a 1 on 4 ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment With MSC in HIV-infected Patients With Controlled Viremia and Immunological Discordant Response
Status: COMPLETED
Conditions: Discordant Immunological Response in HIV Infected Subjects
Interventions: DRUG: Infusion of MSC|DRUG: Infusion of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment of Participants With Metastatic Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostatic Cancer
Interventions: DRUG: Niraparib|DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Placebo|DRUG: New Formulation of Niraparib and Abiraterone Acetate (AA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax in Combination With Intravenous (IV) Obinutuzumab or Oral Ibrutinib in Adult Participants With Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: Venetoclax|DRUG: Ibrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Music Listening on Anxiety and Agitation in People With Mild and Moderate Cognitive Impairment
Status: COMPLETED
Conditions: Anxiety|Agitated Depression
Interventions: BEHAVIORAL: Music Listening|BEHAVIORAL: Listening to Audiobooks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation and Microbiological Assessment of Diode Laser and Chemical Disinfection in Comparison to Selective Caries Removal
Status: COMPLETED
Conditions: Patients With Deep Carious Lesions
Interventions: DEVICE: Diode laser disinfection|OTHER: Chemical disinfection using 2% Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iguratimod in Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: DRUG: Iguratimod|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of rhBMP/BCP With or Without the TSRH® Spinal System for Posterolateral Lumbar Fusion in Patients With Degenerative Disc Disease
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: PROCEDURE: rhBMP-2/BCP|DEVICE: rhBMP-2/BCP/TSRH® Spinal System|DEVICE: Autograft/TSRH® Spinal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosolized Plus Intravenous vs. Intravenous Colistin for VAP Due to Pandrugs-resistant A. Baumannii in Neonates
Status: TERMINATED
Conditions: Pneumonia, Ventilator-Associated|Colistin Adverse Reaction|Infection Due to Multidrug Resistant Acinetobacter|Infection Resistant to Multiple Drugs
Interventions: DRUG: Aerosolized plus intravenous colistin|DRUG: Intravenous colistin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryosurgery and Cream Combination for Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Carac Cream|DRUG: Placebo Cetaphil cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Triplet Combination of Pemetrexed Plus AB928 (Etrumadenant) + AB122 (Zimberelimab) in Patients With Previously Treated Advanced or Metastatic MTAP Deficient Urothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma|Metastatic Cancer
Interventions: DRUG: Pemetrexed|DRUG: Zimberelimab|DRUG: Etrumadenant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belgian Prospective Multicentre Registry on the Performance of the Smart Stent in the Superficial Femoral Artery According to the New Tasc II-classification
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: PROCEDURE: Registry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 18F-deoxyglucose (FDG) PET-CMD
Status: COMPLETED
Conditions: Patients With Idiopathic Dilated Cardiomyopathy
Interventions: DRUG: 18F-deoxyglucose (FDG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ridge Preservation in Molar Sites Comparing Xenograft Versus Mineralized Freeze-dried Bone Allograft
Status: COMPLETED
Conditions: Alveolar Ridge Preservation
Interventions: PROCEDURE: Ridge preservation|DEVICE: bone graft plus a collagen membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease
Status: UNKNOWN
Conditions: Heart Failure|Congenital Heart Disease
Interventions: DRUG: Enalapril Orodispersible Minitablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of (Bio)Sensors for the Identification of Pathogens
Status: RECRUITING
Conditions: Infections|Infection, Bacterial|Infection Viral|Infection, Parasite|SARS CoV 2 Infection|Pseudomonas Aeruginosa Infection|Leishmania Infantum Disease
Interventions: OTHER: Nanobiotechnology platforms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity
Status: COMPLETED
Conditions: Wrinkle|Facial and Neck Skin Laxity
Interventions: DEVICE: micro-excisional skin removal with coring needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Deferiprone sustained-release|DRUG: Deferiprone immediate-release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Preventing Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia
Status: COMPLETED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia Grade 3|Human Papilloma Virus Infection
Interventions: BIOLOGICAL: HspE7|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder|Posttraumatic Stress Disorder|Panic Disorder and Agoraphobia
Interventions: BEHAVIORAL: Transdiagnostic Behavior Therapy|BEHAVIORAL: Cognitive Processing Therapy for PTSD|BEHAVIORAL: Cognitive Behavioral Therapy for MDD|BEHAVIORAL: Cognitive Behavioral Therapy for Panic Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Application of EEN in the Induction of Remission in PUC
Status: NOT_YET_RECRUITING
Conditions: Exclusive Enteral Nutrition|Ulcerative Colitis|Children
Interventions: COMBINATION_PRODUCT: exclusive enteral nutrition|COMBINATION_PRODUCT: regular food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: E-Cigarettes and SNA
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: one time exposure to e-cig with nicotine|OTHER: One time exposure to e-cigarette without nicotine|OTHER: one time exposure to empty e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness
Status: NOT_YET_RECRUITING
Conditions: Disorder of Consciousness|Hemorrhagic Stroke
Interventions: DRUG: Cerebrolysin|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Status: UNKNOWN
Conditions: Arthroplasty Complications|Amputation|Prosthesis-Related Infections
Interventions: DEVICE: Prevena TM|DEVICE: Dry dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Training in Patients With Coronary Heart Disease and Mild Cognitive Impairment
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Coronary Heart Disease
Interventions: BEHAVIORAL: Multi-domain cognitive digital therapy|BEHAVIORAL: Basic cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Brief Behavioral Sleep Intervention for Depression Among Military Veterans
Status: COMPLETED
Conditions: Insomnia|Depression|Suicidal Ideation
Interventions: BEHAVIORAL: Sleep Intervention I|BEHAVIORAL: Sleep Intervention II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: CHOP regimen|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: prednisone|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of PDR001 in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Melanoma|Non-small Sell Lung Cancer (NSCLC)|Triple Negative Breast Cancer|Anaplastic Thyroid Cancer|Other Solid Tumors
Interventions: BIOLOGICAL: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Loss|Gut Microbiome|Anti-Aging
Interventions: BEHAVIORAL: P-IF|BEHAVIORAL: HH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Thresholds Under High-dose Topical Capsaicin
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Topical High dose Capsaicin|DRUG: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Safety of Dexamethasone Eye Drops in Preterm Infants
Status: RECRUITING
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Dexamethasone Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant CCRT With/Without Bevacizumab for Locally Advanced ESCC
Status: UNKNOWN
Conditions: Stage III Esophageal Squamous Cell Carcinoma
Interventions: DRUG: BPF-CCRT (run-in)|DRUG: BPF-CCRT (randomized)|DRUG: PF-CCRT (randomized)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors
Status: RECRUITING
Conditions: Atypical Teratoid Rhabdoid Tumor|INI1 (SMARCB1)-Deficient Primary CNS Malignant Tumors|SMARCA4-deficient Primary CNS Malignant Tumors|Malignant Rhabdoid Tumor (MRT)|Rhabdoid Tumor of the Kidney (RTK)|Epithelioid Sarcoma|Chordoma
Interventions: DRUG: Tazemetostat|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Registry for People With T-cell Lymphoma
Status: RECRUITING
Conditions: T-cell Lymphoma|NK-Cell Lymphoma|T-cell Prolymphocytic Leukemia|T-cell Large Granular Lymphocytic Leukemia|Chronic Lymphoproliferative Disorder of NK Cells|Aggressive NK-cell Leukemia|Systemic Epstein-Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood (Disorder)|Systemic Epstein Barr Virus Positive T-Cell Lymphoproliferative Disease of Childhood|Chronic Active EBV Infection of T-and NK-Cell Type, Systemic Form|Hydroa Vacciniforme-Like Lymphoproliferative Disorder|Adult T-cell Leukemia/Lymphoma|Extranodal NK/T-cell Lymphoma, Nasal Type|Enteropathy-associated T-cell Lymphoma|Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma|Intestinal T-Cell Lymphoma, Not Otherwise Specified|Indolent T-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract|Hepatosplenic T-cell Lymphoma|Subcutaneous Panniculitis-Like T-Cell Lymphoma|Mycosis Fungoides|Sezary Syndrome|Primary Cutaneous Anaplastic Large Cell Lymphoma|Primary Cutaneous T-cell Lymphoma|Primary Cutaneous CD8-Positive Aggressive Epidermotropic T-Cell Lymphoma|Primary Cutaneous Acral CD8-Positive T-Cell Lymphoma|Peripheral T-Cell Lymphoma, Not Otherwise Specified|Angioimmunoblastic T-cell Lymphoma|Follicular T-Cell Lymphoma|Nodal Peripheral T-Cell Lymphoma With TFH Phenotype|Anaplastic Large Cell Lymphoma, ALK-Positive|Anaplastic Large Cell Lymphoma, ALK-negative|Breast Implant-Associated Anaplastic Large Cell Lymphoma
Interventions: OTHER: Optional Blood Sample and Nail Sample
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inclusion Body Myositis Treatment With Celution Processed Adipose Derived Regenerative Cells
Status: ACTIVE_NOT_RECRUITING
Conditions: Inclusion Body Myositis
Interventions: DEVICE: Adipose Derived Regenerative Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the WATCHMAN Left Atrial Appendage (LAA) Closure Device in Patients With Atrial Fibrillation Versus Long Term Warfarin Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DEVICE: WATCHMAN Device|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin 20mg and Metformin SR 750mg|DRUG: CJ-30056 20/750mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Health Care Workers Absenteeism in Covid-19 Pandemic Through BCG Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: BCG Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota
Status: RECRUITING
Conditions: Healthy
Interventions: OTHER: Inulin|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Periarterial Injection Versus Multiple Periveural Injection
Status: COMPLETED
Conditions: Contusion Wrist or Hand|Crush Injury Wrist or Hand
Interventions: PROCEDURE: US-guided periarterial techique|PROCEDURE: US-guided multi-injection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topiramate for Alcohol Use in Posttraumatic Stress Disorder
Status: TERMINATED
Conditions: Alcohol Dependence|Alcoholism|Alcohol Abuse|Alcohol Use Disorder|PTSD|Posttraumatic Stress Disorder
Interventions: DRUG: Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Smoking Cessation in Prediabetic Smokers
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Cigarette Smoking|Prediabetes
Interventions: DRUG: Varenicline for tobacco smoking cessation|BEHAVIORAL: Individualized counseling about both smoking cessation and weight control techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter|Heart Block|Pulmonary Embolism and Thrombosis|Mitral Valve Repair|Sinus Node Dysfunction|Bradycardia|Brady-tachy Syndrome
Interventions: DEVICE: Perclose ProGlide Suture-Mediated Closure System (SMC) - LARGE-BORE PROCEDURES|OTHER: Figure 8 Suture - LARGE-BORE PROCEDURES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Cilostazol Eluting Stent System (CES-1) in De Novo Coronary Artery Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Cilostazol eluting stent system (CES-1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYstic Fibrosis bacterioPHage Study at Yale (CYPHY)
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Standard Dose YPT-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
Status: UNKNOWN
Conditions: Mannose-Binding Lectin Deficiency|Recurrent Pregnancy Loss|Recurrent Implantation Failure|Infertility|Habitual Abortion|Recurrent Miscarriage|Recurrent Spontaneous Abortion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Compatibility of Preoperative Endometrial Biopsies With Postoperative Final Pathology in Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer Stage|Gynecologic Cancer
Interventions: DIAGNOSTIC_TEST: re-evaluation of endometrial biopsy samples by a gynecopathologist working at a university hospital
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Washed Microbiota Transplantation for The Treatment of Oncotherapy-Related Intestinal Complications
Status: RECRUITING
Conditions: Intestinal Complications|Cancer
Interventions: PROCEDURE: Washed Microbiota Transplantation (WMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FEES to Determine Neurological Intensive Care Patients' Oral Diet
Status: COMPLETED
Conditions: Dysphagia|Aspiration Pneumonia|Deglutition Disorders|Intensive Care Neurological Disorder
Interventions: OTHER: Adjustment of oral diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebulized vs. Oral Midazolam Sedation in Pediatric Anesthesia: A Randomized Comparative Study
Status: COMPLETED
Conditions: Preoperative Sedation
Interventions: DRUG: Midazolam nebulized|DRUG: Midazolam oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of the Bifidobacterium Longum BL21 on BMI, Metabolic Indicators, and Gut Microbiota in Overweight/Obese Adults
Status: NOT_YET_RECRUITING
Conditions: Overweight/Obese Adults
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Metabolic Acidosis
Interventions: DIETARY_SUPPLEMENT: Alkalizing Fruit and Vegetables|DRUG: Sodium bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 Trial
Status: RECRUITING
Conditions: Hypopharyngeal Cancer
Interventions: DRUG: Docetaxel|DRUG: 5-fluorouracil|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiation Therapy|DRUG: Platinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Observational Study Comparing Computer-Assisted Paramedian Approach Versus Conventional Midline Approach for Lumbar Puncture
Status: NOT_YET_RECRUITING
Conditions: Spinal Puncture
Interventions: PROCEDURE: Computer-Assisted Paramedian Approach Technique|PROCEDURE: Conventional Midline Approach Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders
Status: COMPLETED
Conditions: Sleep Apnea|Sleep Apnea, Obstructive|Sleep Apnea Syndromes|Pain|Pain, Face|Temporomandibular Disorder
Interventions: COMBINATION_PRODUCT: osa treatment|OTHER: no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization Strategy for the Prevention of AMS by RIPC Combined With Acetazolamide
Status: COMPLETED
Conditions: Acute Mountain Sickness
Interventions: DRUG: Acetazolamide|DEVICE: Doctormate® (twice daily for 6 days)|DEVICE: Doctormate® (forth daily for 3 days)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CT-validation of Ultrasound Based Planning for High Dose Rate (HDR) Prostate Brachytherapy Using Vitesse
Status: COMPLETED
Conditions: Prostate Cancer|Interstitial Radiation|High Dose Rate Brachytherapy|Ultrasound-based Planning Compared to CT-based Planning
Interventions: RADIATION: HDR prostate brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma
Status: COMPLETED
Conditions: AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Primary CNS Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Chondrosarcoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Osteosarcoma|Nodal Marginal Zone B-cell Lymphoma|Ovarian Sarcoma|Primary Central Nervous System Non-Hodgkin Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Osteosarcoma|Recurrent Small Lymphocytic Lymphoma|Recurrent Uterine Sarcoma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult Soft Tissue Sarcoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Stage IV Uterine Sarcoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: tanespimycin|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vincristine, Dactinomycin, and Cyclophosphamide With or Without Radiation Therapy in Treating Patients With Embryonal Rhabdomyosarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: cyclophosphamide|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response and Safety Comparison of 3 Lots of GSK Biologicals' DTaP-IPV Candidate Vaccine to DTaP + IPV Vaccines
Status: COMPLETED
Conditions: Tetanus|Acellular Pertussis|Diphtheria
Interventions: BIOLOGICAL: SB213503 lot 1|BIOLOGICAL: SB213503 lot 2|BIOLOGICAL: SB213503 lot 3|BIOLOGICAL: Infanrix|BIOLOGICAL: IPOL|BIOLOGICAL: M-M-R II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Consumer Perception of an Experimental Mouthwash After a Single Use in Dry Mouth Subjects
Status: COMPLETED
Conditions: Xerostomia
Interventions: OTHER: Biotene mouthwash|OTHER: Bottled mineral water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: High-concentration Small-volume Versus Low-concentration Large-volume Iodine Solution for Esophageal Chromoendoscopy
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: 1% Lugol's iodine solution|DRUG: 5% Lugol's iodine solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Collagen for Treatment of Musculoskeletal Injuries
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries|Hallux Rigidus
Interventions: PROCEDURE: Anterior cruciate ligament reconstruction, using graft, augmented with collagen membrane|PROCEDURE: Anterior cruciate ligament reconstruction, using graft, not augmented with collagen membrane (control group)|PROCEDURE: Resection arthroplasty of the first metatarsophalangeal joint with the introduction of a collagen membrane into the joint cavity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This is a Phase 1 Study to Evaluate the Safety,Tolerability and Virology of CT P59 in Patients With Mild Symptoms of Symptoms of Coronavirus Disease (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: CT-P59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carotid Atherosclerosis : Innovative Imaging Biomarkers. Study Case-control
Status: RECRUITING
Conditions: Carotid Stenosis
Interventions: DEVICE: HITS quantification, Ultrasound examinations, High Resolution MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Assessment of Color Stability and Patient Satisfaction for Polished Versus Glazed Lithium Disilicate Glass Ceramic Restorations and Patient Satisfaction
Status: UNKNOWN
Conditions: Color Change of Lithium Disilicate Crowns
Interventions: OTHER: glazed lithium disilicate crowns|OTHER: polished lithium disilicate crowns
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Integrated Assessment of the Safety and Effectiveness of Bexagliflozin for the Management of Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Bexagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Trial of ADU-S100 and Pembrolizumab in Head and Neck Cancer
Status: TERMINATED
Conditions: Metastatic Head and Neck Cancer|Recurrent Head and Neck Cancer
Interventions: DRUG: ADU-S100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minipterional Versus Pterional Craniotomy
Status: UNKNOWN
Conditions: Intracranial Aneurysm|Muscular Atrophy
Interventions: PROCEDURE: Minipterional craniotomy|PROCEDURE: Pterional craniotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Natural Killer (NK) Cell Therapy in Patients With Lymphoma or Solid Tumor
Status: COMPLETED
Conditions: Malignant Lymphomas|Solid Tumors
Interventions: BIOLOGICAL: Allogeneic NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of High-Volume Walking With Visual Cues (VC) in Parkinson´s Disease (PD)
Status: COMPLETED
Conditions: Parkinson´s Disease
Interventions: OTHER: Visual Cues|OTHER: Walking without visual cues
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT