pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: IM Screw vs. K-wire Fixation of Proximal/Middle Phalanx Fractures
Status: NOT_YET_RECRUITING
Conditions: Hand; Fracture, Phalanx
Interventions: DEVICE: Intramedullary screw|DEVICE: Kirschner wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 - Multicentre Study on Nosocomial Transmission of SARS-CoV-2 Virus: an Ancillary Study (NOSO-COR IMMUNO)
Status: COMPLETED
Conditions: Infection Viral
Interventions: OTHER: Collection of blood, salivary and nasopharyngeal samples.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Centella Asiatica Cream on Scar Tenderness Who Underwent Open Carpal Tunnel Release Surgery
Status: COMPLETED
Conditions: To Prevent Scar Formation for Patients Underwent Surgery
Interventions: DRUG: undefinedCentella Asiatica Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Microbiome and Resilience to Sleep and Circadian Disruption
Status: UNKNOWN
Conditions: Sleep Deprivation|Circadian Dysregulation|Stress
Interventions: BEHAVIORAL: Insufficient Sleep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Books, Videos And Mobile Games İn Pediatric Dentistry
Status: COMPLETED
Conditions: Dental Anxiety|Child, Only
Interventions: BEHAVIORAL: playing mobile game|BEHAVIORAL: reading book|BEHAVIORAL: watching video|BEHAVIORAL: tell-show-do group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CM24 in Combination With Nivolumab in Adults With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor|Non Small Cell Lung Cancer|Pancreatic Cancer|Ovarian Cancer|Papillary Thyroid Cancer|Melanoma|Colorectal Adenocarcinoma
Interventions: DRUG: CM-24 and Nivolumab - Dose Escalation|DRUG: CM-24, Nivolumab, Nab paclitaxel and Gemcitabine - Expansion|DRUG: CM-24, Nivolumab, and Nal-IRI/5-FU/LV - Expansion|DRUG: Nivolumab, Nab paclitaxel and Gemcitabine - Expansion|DRUG: Nivolumab and Nal-IRI/5-FU/LV - Expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Effectiveness of PoNS Device to Treat Chronic Balance Deficit Due to Traumatic Brain Injury (TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury|Chronic Balance Disorder
Interventions: DEVICE: Cranial nerve non-invasive neuromodulation via PoNS device|DEVICE: Sham PoNS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Citalopram Hydrobromide Tablets 40 mg of Dr.Reddy's Laboratories Limited Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram Hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy of Acute Myeloid Leukemia in Patients Over the Age of 60 : DA Versus Mitoxantrone With Intermittent AraC
Status: COMPLETED
Conditions: Leukemia, Nonlymphocytic, Acute
Interventions: DRUG: randomization between two established Chemotherapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Guided Versus Conventional Surgical Removal of Deeply Impacted Mandibular Third Molar With Preservation of External Oblique Ridge
Status: UNKNOWN
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: computer guided surgical|PROCEDURE: Conventional surgery|DEVICE: CBCT|DEVICE: CBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RMPT for Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Revlimid, Melphalan, Prednisone, Thalidomide|DRUG: Revlimid, Melphalan, Prednisone, Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mode Specific Effects of Isokinetic Training of Hamstring on Hamstring to Quadriceps Ratio
Status: COMPLETED
Conditions: Muscle Strength
Interventions: OTHER: Eccentric isokinetic training|OTHER: Concentric isokinetic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2, Randomized Dose-ranging Study to Evaluate the Efficacy of Tralokinumab in Adults With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: Tralokinumab|BIOLOGICAL: Tralokinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: One Year Study to Evaluate Three Different Adjuvanted Doses of the Recombinant Plague Vaccine (rF1 and rV Antigens)
Status: COMPLETED
Conditions: Plague
Interventions: BIOLOGICAL: Alhydrogel|BIOLOGICAL: rF1 and rV protein antigens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Effectiveness Trial of VA S.A.V.E.
Status: NOT_YET_RECRUITING
Conditions: Suicide Prevention
Interventions: BEHAVIORAL: VA S.A.V.E.|BEHAVIORAL: Control training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TL-895 and KRT-232 Study in Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: TL-895|DRUG: KRT-232
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sugammadex and Decreased Time to Extubation
Status: COMPLETED
Conditions: Coronary Artery Bypass Graft and/or Aortic Valve Replacement Surgery
Interventions: DRUG: Sugammadex|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Videoconferencing Between Ambulances and Physician at the Emergency Medical Dispatch Center, Effects on On-Site Patient Treatment and Patterns of Referral
Status: UNKNOWN
Conditions: Acute Illness|Acute Injury
Interventions: DEVICE: Video consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 26 Week Efficacy, Safety and Tolerability Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|COPD|Lung Diseases, Obstructive
Interventions: DRUG: Indacaterol|DRUG: Formoterol (12 µg b.i.d.)|DRUG: Tiotropium (18 µg o.d.)|DRUG: Placebo to Indacaterol|DRUG: Placebo to Formoterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Additional Effect of Pain Neuroscience Education to Orofacial and Neck Exercises in Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: OTHER: Pain Neuroscience Education (PNE)|OTHER: Orofacial Manual Therapy|OTHER: Orofacial Exercises|OTHER: Neck Motor Control Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat
Status: COMPLETED
Conditions: Moderate to Severe Convexity of Submental Fat|Safety|Efficacy
Interventions: DRUG: Deoxycholic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-LPS Antibody Treatment for Pediatric NAFLD
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)
Interventions: BIOLOGICAL: IMM-124E|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of UCA-PSCs in Women With POF
Status: COMPLETED
Conditions: Premature Ovarian Failure
Interventions: PROCEDURE: transplantation of human UCA-PSCs or WJ-MSCs into ovaries of POF patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Sodium Glucose Cotranspoter 2 Inhibitors On Heart And Kidneys In Fabry Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Fabry Disease
Interventions: DRUG: Dapagliflozin 10mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Cervical Consistency Index and Uterocervical Angles in Medical Termination
Status: COMPLETED
Conditions: Second Trimester Abortion|Uterocervical Angle|Cervical Consistency Index
Interventions: OTHER: abortus within 24 hours or 24-48 hours
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy
Status: COMPLETED
Conditions: Hyperemesis Gravidarum|Nausea Gravidarum|Vomiting of Pregnancy
Interventions: DRUG: Capsaicin Topical Cream|DRUG: Metoclopramide|DRUG: Ondansetron|DRUG: Lactated Ringers, Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antacids on the Pharmacokinetics (PK) of Raltegravir in Human Immunodeficiency Virus (HIV)-Infected Participants (MK-0518-824)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Raltegravir 1200 mg|DRUG: TUMS|DRUG: Leader Antacid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Point-of-Care EID for HIV-Exposed Infants
Status: COMPLETED
Conditions: HIV/AIDS|Infant Morbidity|Pediatric HIV Infection|Transmission, Perinatal Infection
Interventions: DIAGNOSTIC_TEST: Point of Care Early Infant Diagnosis|DIAGNOSTIC_TEST: Standard of Care Early Infant Diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sedation for Patients Undergoing Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Biliary Colic
Interventions: DRUG: Propofol|DRUG: Diclofenac Sodium and Lignocaine 10 % spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Intravenous and Intranasal Oxytocin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: intravenous oxytocin|DRUG: intranasal oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor
Status: RECRUITING
Conditions: Advanced Solid Tumor|Lung Cancer|Pancreas Cancer|Breast Cancer|Thyroid Cancer|Colorectal Cancer|Cervical Cancer|Ovarian Cancer|Vulva Cancer
Interventions: DRUG: CNSI-Fe(II) 30 mg|DRUG: CNSI-Fe(II) 60 mg|DRUG: CNSI-Fe(II) 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: SL spray|DRUG: SL film
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prevention of Chemotherapy-Induced Ovarian Failure With Goserelin in Premenopausal Lymphoma Patients
Status: ENROLLING_BY_INVITATION
Conditions: Premature Ovarian Failure
Interventions: DRUG: Goserelin|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Paricalcitol Over Inflammatory Parameters on Chronical Kidney Disease Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Paricalcitol|DRUG: Paricalcitol, atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stress Management Intervention Among Breast and Gynecologic Cancer Patients in Viet Nam
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Gynecologic Cancer
Interventions: BEHAVIORAL: Vietnamese Self-Help Plus (vSH+)|OTHER: 'Doing What Matters in Times of Stress' (DWM) Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Daily Oral Administration of Food Supplement NLC-V in Patients Diagnosed With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: NLC-V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects
Status: COMPLETED
Conditions: Dermatitis|Dermatitis, Atopic|Eczema|Skin Diseases|Skin Diseases, Genetic|Genetic Diseases, Inborn|Skin Diseases, Eczematous|Hypersensitivity|Hypersensitivity, Immediate|Immune System Diseases
Interventions: DRUG: PF-04965842 100 mg|DRUG: PF-04965842 200 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Anti-Influenza Intravenous Hyperimmune Immunoglobulin (IVIG) in Adults Hospitalized With Influenza
Status: COMPLETED
Conditions: Influenza A|Influenza B
Interventions: BIOLOGICAL: Intravenous hyperimmune immunoglobulin (IVIG)|BIOLOGICAL: Placebo for IVIG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing the Effects of Linear Versus Nonlinear Aerobic Training in Women With Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Linear Aerobic Training|BEHAVIORAL: Nonlinear Aerobic Training|BEHAVIORAL: Progressive Stretching|OTHER: Cardiopulmonary exercise test (CPET)|OTHER: Blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Post Operative Pain|Emergence Delirium
Interventions: DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: Dexmedetomidine|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Cold Sore Patch for the Treatment of Herpes Labialis
Status: COMPLETED
Conditions: Herpes Labialis
Interventions: DEVICE: Patch ( Compeed© Total CareTM Cold Sore Patch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Secukinumab in Adult Patients With Skin Types IV-VI With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Secukinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bi-weekly Cetuximab Combined With 5-fluorouracil/Leucovorin/Oxaliplatin (FOLFOX-6) in Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Helminthiasis|Filariasis
Interventions: DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Hormones and Radiation for Intermediate or High Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Bicalutamide|DRUG: Dutasteride|DRUG: Finasteride|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Genotoxicity of Desflurane and Propofol
Status: COMPLETED
Conditions: DNA Damage|Anesthesia
Interventions: DRUG: Anesthetics, General Desflurane Maintenance|DRUG: Anesthetics, General Propofol Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: OTHER: nutraceutical combination (red yeast rice, policosanols and berberine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine if the Valiant Stent Graft is Safe and Effective in Treating Patients Who Have a Blunt Thoracic Aortic Injury
Status: COMPLETED
Conditions: Blunt Thoracic Aortic Injury
Interventions: DEVICE: Valiant Thoracic Stent Graft with the Captivia Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIBG With Dinutuximab +/- Vorinostat
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroblastoma
Interventions: RADIATION: 131I-MIBG|DRUG: Dinutuximab|DRUG: Vorinostat|DRUG: Sargramostim|DRUG: Potassium Iodide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leukocyte and and Platelet-rich Fibrin Plasma for the Prevention of Anastomotic Leakage in Colorectal Anastomosis
Status: COMPLETED
Conditions: Anastomotic Leak|Platelet-Rich Fibrin|Colorectal Surgery
Interventions: BIOLOGICAL: Platelet rich fibrin on colorectal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasal High Flow Versus Non-invasive Ventilation for Early Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Hypercapnic Acidosis
Status: NOT_YET_RECRUITING
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease|Hypercapnic Acidosis|Respiratory Failure With Hypercapnia
Interventions: DEVICE: Ventilatory support via nasal high flow|DEVICE: Ventilatory support via NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supine vs Prone Position During Delayed Cord Clamping
Status: COMPLETED
Conditions: Newborn; Anemia|Umbilical Cord Problem
Interventions: PROCEDURE: supine or prone position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A New Intervention Method to Enhance Oral Feeding Ability in Premature Infants: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Feeding; Difficult, Newborn|Premature
Interventions: PROCEDURE: New Method|PROCEDURE: Conventional Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Escalating Doses of Thalidomide in Conjunction With Bortezomib and HIgh Dose Melphalan for BSCT
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide+Melphalan +Bortezomib+stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Brexpiprazole With That of Risperidone
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: brexpiprazole|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Resuscitation Interdisciplinary Consultation System: a Randomized, Multicenter, Interventional Study to Assess Quality of Life After a Stay in the COPRéa Intensive Care Unit
Status: RECRUITING
Conditions: Post Intensive Care Syndrome
Interventions: OTHER: Psychological and quality of life questionnaires|OTHER: Interdisciplinary consultation at 4/5 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Whole Eye Optical Coherence Tomography (OCT) to Improve Refractive Surgery and Eye Care
Status: TERMINATED
Conditions: Image, Body
Interventions: DEVICE: Optical Coherence Tomography (OCT)|DEVICE: Magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Efficacy Study of VI-0521 to Evaluate the Long Term Treatment of Obesity in Adults With Obesity-Related Co-Morbid Conditions. An Extension Study of Protocol OB-303 (NCT00553787)
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: VI-0521|DRUG: Placebo|DRUG: VI-0521
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Comparison of Gastric Volume After Three Modes of Positive Facemask During Induction of Anaesthesia
Status: UNKNOWN
Conditions: Positive-Pressure Respiration|Respiratory Aspiration of Gastric Content
Interventions: OTHER: Diagnostic ultrasonography of gastric volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Laparoscopic Surgery and Abdominal Compliance
Status: UNKNOWN
Conditions: Patients Ongoing Elective Abdominal Laparoscopy
Interventions: DRUG: propofol|DRUG: NMBA - cisatracurium|DRUG: placebo - isotonic saline serum|DRUG: sufentanil|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: SURF, Neurodevelopment, Growth Study in SGA Infants
Status: WITHDRAWN
Conditions: Infant, Small for Gestational Age
Interventions: OTHER: Standard Formula|OTHER: Nutrient-enriched Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-Dideoxyinosine
Status: COMPLETED
Conditions: AIDS-Related Complex|Acquired Immunodeficiency Syndrome
Interventions: DRUG: zidovudine|DRUG: 2',3'-dideoxyinosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Complications in Singleton Pregnancies Following Previous Cesarean Myomectomy
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Cesarean section with cesarean myomectomy (serosal)|PROCEDURE: Cesarean section without myomectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: LIPS-A: Lung Injury Prevention Study With Aspirin
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Aspirin|DRUG: Lactose powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resistance Training in HFpEF
Status: COMPLETED
Conditions: Heart Failure Preserved Ejection Fraction
Interventions: OTHER: Resistance Exercise Training|RADIATION: DEXA bone scan|OTHER: Cardiopulmonary Max Exercise Test|OTHER: Quality of Life Questionnaire|OTHER: Submaximal Exercise Test|OTHER: Blood Draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Determine the Risk of Cancer in Rheumatoid Arthritis (RA) Patients Who Use Abatacept and Other Biologic Agents
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Non-Interventional|OTHER: Non-Interventional|OTHER: Non-Interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Triticale, Mung Bean and Adzuki Bean Intervention on Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: triticale and mung bean|DIETARY_SUPPLEMENT: adzuki bean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Compression Garments for Recovery in Modern Pentathletes
Status: UNKNOWN
Conditions: Muscle Damage
Interventions: DEVICE: Compression garments|OTHER: Sham recovery drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rectal Indomethacin to Prevent Post ESWL-pancreatitis
Status: COMPLETED
Conditions: Pancreatitis
Interventions: DRUG: indomethacin suppository|DRUG: Glycerin Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Relaxation Training by Tele-Rehabilitation in Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Telerehabilitation-based relaxation exercise group (EG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doxorubicin and Cyclophosphamide Plus Paclitaxel With or Without Trastuzumab in Treating Women With Node-Positive Breast Cancer That Overexpresses HER2
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: herceptin|DRUG: adriamycin|DRUG: cyclophosphamide|DRUG: taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of Single-dose Injection of SHR-2004 in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Prevention of Arterial and Venous Thrombosis
Interventions: DRUG: SAD, SHR-2004|DRUG: SAD, SHR-2004 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Immediate Implant Placement In The Esthetic Zone Using the Bone Shielding Concept Versus Dual Zone Therapy
Status: COMPLETED
Conditions: Immediate Implants|Alveolar Bone Loss|Dual Zone Technique|the Bone Shielding Concept|Esthetic Zone
Interventions: PROCEDURE: immediate implant placement with The Dual-Zone Therapeutic Concept|PROCEDURE: Immediate implant placement with the bone shielding concept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weekly Paclitaxel Plus Gemcitabine as Second-line in Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitors
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H0731|DRUG: Placebo|DRUG: NrtI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicentre Booster & Immune Memory Study of a Booster Dose of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine or a Single Dose of 23-valent Plain Polysaccharide Vaccine in Healthy Children Aged 11-18 Mths, Previously Vaccinated in Study 103488
Status: COMPLETED
Conditions: Acellular Pertussis|Tetanus|Hepatitis B|Diphtheria|Haemophilus Influenzae Type b|Poliomyelitis
Interventions: BIOLOGICAL: Pneumococcal (vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Study on Salt Intake and Energy Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Salt|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ixazomib, Lenalidomide, and Combination for Maintenance in NDMM Patients
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5024048 in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Chronic Hepatitis C Genotype 1 or 4
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: RO5024048|DRUG: Ribavirin [Copegus]|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Clinical Trail of NTQ2494 Tablets in Patients With Advanced Hematological Malignancies
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML)
Interventions: DRUG: NTQ2494 tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Classroom-based Intervention Promoting a Prosocial Classroom Climate in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Child Behavior
Interventions: BEHAVIORAL: SterkWerk|BEHAVIORAL: Treatment-as-usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Blue Laser Imaging (BLI) for Detection of Secondary Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Head Neck Cancer|Esophageal Cancer|Gastrostomy
Interventions: DIAGNOSTIC_TEST: blue laser imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)
Status: RECRUITING
Conditions: Beta Lactam Resistant Bacterial Infection|Enterobacteriaceae Infections|Bacteremia
Interventions: DRUG: Piperacillin/tazobactam|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol
Status: COMPLETED
Conditions: Mucociliary Clearance
Interventions: DRUG: nebulized albuterol (2.5 mg/3ml/dose)|DRUG: nebulized levalbuterol (1.25 mg/3ml/dose)|DRUG: nebulized placebo (3ml/dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study Of Indiplon/Placebo With Sertraline In Insomnia Co-Existing With Depression
Status: TERMINATED
Conditions: Insomnia|Depression
Interventions: DRUG: Indiplon|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Ciprofloxacin for Inhalation in Patients With Non-Cystic Fibrosis Bronchiectasis "ORBIT-1"
Status: COMPLETED
Conditions: Non-Cystic Fibrosis Bronchiectasis
Interventions: DRUG: Ciprofloxacin for Inhalation|DRUG: Ciprofloxacin for Inhalation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Fingolimod in Lung Cancers
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer|Small-cell Lung Cancer
Interventions: DRUG: Fingolimod 0.5 milligram (mg) [Gilenya]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Frequency Optimization,Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received Up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess GW642444 in Asthma Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GW642444M|DRUG: GW642444H|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BM-MSCs in DCD Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplantation|Acute Kidney Tubular Necrosis
Interventions: OTHER: bone marrow-derived mesenchymal stem cells|OTHER: Saline|DRUG: Induction therapy (ATG or Basiliximab)|DRUG: Maintenance therapy (Low-dose CNI + MPA + steroids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Customized Software for Foot-related Exercises (SOPeD) for Prevention and Treatment in People With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies
Interventions: OTHER: Physical therapy by foot-ankle segmental and functional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Injectable Composite Resins in Class I Cavities
Status: ACTIVE_NOT_RECRUITING
Conditions: Caries,Dental
Interventions: DEVICE: GC Geanial Injectable (Tokyo,Japan)|DEVICE: 3M Filtek Z250 Universal Restorative (Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Prucalopride vs. Polyethylene Glycol 3350 on Colon Activity
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: prucalopride|DRUG: PEG 3350
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: mHealth Intervention for Increasing COVID-19 Prevention Practices With Urban Refugee and Displaced Youth in Uganda
Status: COMPLETED
Conditions: Knowledge, Attitudes, Practice|Covid19
Interventions: BEHAVIORAL: Kukaa Salama: mHealth intervention|DEVICE: Face Mask + Soap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjunct Targeted Temperature Management in Acute Severe Carbon Monoxide Poisoning
Status: RECRUITING
Conditions: Carbon Monoxide Poisoning|Neurologic Sequelae|Hypothermia
Interventions: OTHER: Targeted therapeutic hypothermia|OTHER: Targeted therapeutic normothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Double-blind Study for the Use of Aspirin During Transurethral Surgery of the Bladder or the Prostate
Status: WITHDRAWN
Conditions: Blood Loss, Surgical|Intraoperative Complications|Re-operation Rates in Patients With Aspirin Treatment
Interventions: DRUG: transurethral surgery with or without aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Measure the Effects of Specific Thoracic Chiropractic Adjustments on Blood Pressure and Pulse Rate
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Activator IV Adjusting Instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of DP-b99 in Treating Acute Ischemic Stroke
Status: TERMINATED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: DP-b99|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Aganirsen in iCRVO Patients at Risk of Developing NVG
Status: UNKNOWN
Conditions: Ischaemic Central Retinal Vein Occlusion|Neovascular Glaucoma
Interventions: DRUG: aganirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Dose Escalation Study of Intradermal gp160 to Evaluate Safety, Delayed Type Hypersensitivity (Skin Test) Responses and Immunogenicity in Asymptomatic HIV Seropositive Patients With More Than 400 CD4+ Cells
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Anacetrapib (MK0859) in Subjects With Impaired Renal Function (MK-0859-038)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: anacetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Examine Whether Urinary Partial Oxygen Pressure Measurements Are Indicative of the Postoperative Occurrence of Acute Kidney Injury (AKI) in Individuals Who Have Undergone Liver Transplantation
Status: NOT_YET_RECRUITING
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: urinary partial oxygen pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Group Study to Evaluate the Efficacy of a Cosmetic Product Line on Acne Symptoms
Status: COMPLETED
Conditions: Acne
Interventions: OTHER: EQ Exfoliating Cleanser|OTHER: EQ Gel|OTHER: EQ Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Varenicline as a Treatment for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence|Methamphetamine Abuse|Substance Abuse
Interventions: DRUG: Placebo|DRUG: Varenicline|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Status: RECRUITING
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: Vedolizumab IV|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Nelarabine Injection in Patients With T-lymphoblastic Leukemia and T-lymphoblastic Lymphoma
Status: NOT_YET_RECRUITING
Conditions: T-lymphoblastic Leukemia|T-lymphoblastic Lymphoma
Interventions: DRUG: Nelarabine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacoinvasive Therapy With Prourokinase
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: DRUG: Prourokinase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Appendicectomy Versus Antibiotics in the Treatment of Acute Uncomplicated Appendicitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Appendicitis
Interventions: PROCEDURE: Appendicectomy|DRUG: Ertapenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD
Status: WITHDRAWN
Conditions: COPD|Exacerbation
Interventions: DRUG: mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Erector Spina Plan Block and Trnsversus Abdominis Plan Block in Laparoscopic Nephrectomy: Prospective Randomized Clinical Trial
Status: RECRUITING
Conditions: Laparoscopic Nephrectomy
Interventions: PROCEDURE: laparoscopic nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: RDEA3170 and Febuxostat Drug Interaction Study
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: RDEA3170 10 mg|DRUG: Febuxostat 40 mg|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: REstrictive Versus LIberal Oxygen Strategy and Its Effect on Pulmonary Hypertension After Out-of-hospital Cardiac Arrest (RELIEPH-study)
Status: UNKNOWN
Conditions: Hypertension, Pulmonary Arterial|Out-Of-Hospital Cardiac Arrest|Intensive Care Unit|Oxygen Therapy|Mechanical Ventilation|Resuscitation
Interventions: OTHER: Restrictive PaO2|OTHER: Low normal MAP|OTHER: Liberal PaO2|OTHER: High normal MAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Papulopustular Rosacea Study
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: CD5024|DRUG: Azelaic acid 15% Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Single-Center, Open Label Study of Autologous, Adoptive Cell Therapy Following a Reduced Intensity, Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Urothelial Carcinoma Patients
Status: UNKNOWN
Conditions: Metastatic Urothelial Carcinoma
Interventions: PROCEDURE: Tumor Infiltrating Lymphocytes (TIL)|DRUG: Proleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Preventive Treatment (IPTp) Versus Rapid Diagnostic Testing (RDT) and Treatment of Malaria in Pregnancy
Status: COMPLETED
Conditions: Malaria|Anaemia|Pregnancy
Interventions: DRUG: Amodiaquine plus artesunate combination; sulphadoxine-pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT