pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity
Status: RECRUITING
Conditions: Respiratory Failure|Obesity
Interventions: OTHER: transpulmonary pressure guided positive end expiratory pressure|OTHER: standard positive end expiratory pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: COMBINATION_PRODUCT: Alirocumab and Cemiplimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of LNP023 in Primary IgA Nephropathy Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: IgA Nephropathy
Interventions: DRUG: Placebo|DRUG: LNP023
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Motexafin Gadolinium for the Treatment of Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: Motexafin gadolinium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Asthma Study Using Stepwise Treatment With Two Food And Drug Administration Approved Asthma Medications
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salmeterol/Fluticasone propionate combination product|DRUG: Fluticasone propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment Crestal Maxillary Sinus Membrane Elevation Using Different Implant Heights
Status: UNKNOWN
Conditions: Bone Formation Around Implant After Crestal Sinus Lifting
Interventions: PROCEDURE: trans-crestal sinus lifting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Retinitis Pigmentosa Via Electromagnetic Stimulation and Platelet Rich Plasma
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: COMBINATION_PRODUCT: PRP combined Magnovision|BIOLOGICAL: PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Subjects Greater Than 40 Years of Age With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: formoterol fumarate inhalation solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Freeze Dried Strawberry Powder Supplementation on Vascular Function and Blood Markers of Cardiovascular Risk
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Low Dose Strawberry Powder|DIETARY_SUPPLEMENT: High Dose Strawberry Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CaffeinICU Study - A Study on Oral Caffeine in ICU Patients With Coma
Status: SUSPENDED
Conditions: Depressed GCS
Interventions: DRUG: Caffeine Citrate 20 MG/ML Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CellFX Comparison to Cryosurgery in Cutaneous Non-Genital Common Warts
Status: COMPLETED
Conditions: Warts|Warts Hand|Verruca
Interventions: DEVICE: CellFX System Device|DEVICE: Cryosurgery Liquid Nitrogen Sprayer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess The Efficacy and Safety of a PARP Inhibitor For The Treatment of BRCA-positive Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot Study
Status: COMPLETED
Conditions: Endothelial Function|Lipids|Insulin Resistance|Inflammation|HIV Infections
Interventions: DRUG: Etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Capecitabine and Oxaliplatin With or Without Cetuximab in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine and oxaliplatin + cetuximab|DRUG: capecitabine and oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 4 Weeks of Oral D. Piger on Safety, Pharmacokinetics and Ethanol Metabolism in Overweight Individuals (2023)
Status: RECRUITING
Conditions: Obesity|Metabolic Syndrome|Steatosis of Liver
Interventions: DIETARY_SUPPLEMENT: D piger|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diastolic Performance and Norepinephrine in Spinal-Induced Hypotension for Cesarean Delivery
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Norepinephrine|DEVICE: ClearSight®, Edwards Lifescience, Irvine, CA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: GELSECTAN® and Covert Hepatic Encephalopathy
Status: WITHDRAWN
Conditions: Covert Hepatic Encephalopathy
Interventions: DIETARY_SUPPLEMENT: Gelsectan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine or Endocrinotherapy as a Maintenance Therapy Regimen at Least 2nd Line in Hormone Receptor Positive and HER2 Negative Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of INV-202 in Patients With Obesity and Metabolic Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Metabolic Syndrome
Interventions: DRUG: INV-202|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects and Mechanisms of Sensory Afferent Electrostimulation on Upper Limb Function in Patients With Hemiparesis
Status: NOT_YET_RECRUITING
Conditions: Hemiparesis|Unilateral Cerebral Palsy
Interventions: OTHER: SAES|OTHER: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?
Status: UNKNOWN
Conditions: Male Infertility
Interventions: DIETARY_SUPPLEMENT: Porimore - A Carnitine based food supplement|DIETARY_SUPPLEMENT: Zinc and Folate Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of COVID-19 on Platelet Mitochondrial Bioenergetic, Antioxidants and Oxidative Stress in Infertile Men.
Status: UNKNOWN
Conditions: Infertility, Male|COVID-19
Interventions: OTHER: diagnostic test and sperm analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupuncture for Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DEVICE: Verum acupuncture (30# acupuncture needle)|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Surface Antigen, Inactivated, Adjuvanted With MF59C.1 Influenza Vaccine, Formulation 2008-2009
Status: COMPLETED
Conditions: Interpandemic Influenza
Interventions: BIOLOGICAL: Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Profile of Vincristine Administered With Imatinib for Bcr-Abl Positive Acute Lymphoblastic Leukemia (ALL) Compared to That Without Imatinib for Bcr-Abl Negative ALL
Status: TERMINATED
Conditions: Acute Lymphoblastic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monitoring of Perfusion in Sepsis and Malaria
Status: COMPLETED
Conditions: Severe Sepsis|Malaria
Interventions: PROCEDURE: Lung Ultrasound examination|PROCEDURE: Compression ultrasonography (CUS)|PROCEDURE: Echocardiography|PROCEDURE: Inferior Vena Cava ultrasound|PROCEDURE: Passive leg raising test (PLR)|PROCEDURE: Orthogonal polarization spectral imaging (OPS)|PROCEDURE: Urine collection (Foley catheter)|PROCEDURE: Venous blood samplings|PROCEDURE: Electrocardiogram|PROCEDURE: GlycoCheck
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Amyloidosis Cardiac|Amyloid Polyneuropathy|Amyloidosis|Heart Failure|Cardiomyopathy Non-Dilated|Cardiomyopathies, Secondary
Interventions: DIAGNOSTIC_TEST: Specific diagnostic work-up for ATTR-CM patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of FOLFOXIRI Plus Cetuximab vs. FOLFOXIRI Plus Bevacizumab
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: fluorouracil|DRUG: Leucovorin|DRUG: irinotecan|DRUG: oxaliplatin|BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Intravenous Administration of TB-402 for the Prophylaxis of Venous Thromboembolic Events (VTE) After Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Total Knee Replacement Surgery
Interventions: DRUG: TB-402|DRUG: Enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sarcopenia in Colorectal Cancer Patients, Intervention Study
Status: RECRUITING
Conditions: Sarcopenia|Postoperative Complications|Infection;Post Surg Procedure
Interventions: DIETARY_SUPPLEMENT: Protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes?
Status: TERMINATED
Conditions: Cerebral Palsy
Interventions: DRUG: oral baclofen + placebo|DRUG: placebo + oral baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ozone Therapy in Endodontic Practice, in Vivo Study
Status: COMPLETED
Conditions: Primary Apical Periodontite
Interventions: DRUG: Ozone|DRUG: Control (no last irrigation)|DRUG: Aqueous Ozone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methylphenidate Treatment for Cocaine Abuse and ADHD - 1
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity|Cocaine-Related Disorders
Interventions: DRUG: Methylphenidate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Emtansine (T-DM1) in HER2-positive Breast Cancer Patients With Progressive Disease After TKIs or HP Therapy
Status: RECRUITING
Conditions: Advanced Breast Cancer|Objective Response Rate|Trastuzumab Emtansine
Interventions: DRUG: Trastuzumab Emtansine (T-DM1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine, Doxorubicin, and Cyclophosphamide in Treating Children With Relapsed or Refractory Solid Tumors or Neuroblastoma
Status: COMPLETED
Conditions: Recurrent Neuroblastoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: decitabine|DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|BIOLOGICAL: filgrastim|BIOLOGICAL: pegfilgrastim|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study : Helicobacter Pylori Eradication Therapy in Accordance With Past Antibiotics Use
Status: UNKNOWN
Conditions: Helicobacter Eradication
Interventions: DRUG: Helicobacter pylori eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Premedication With Atenolol Versus Metoprolol for Controlled Hypotensive Anesthesia During Nasal Surgeries
Status: RECRUITING
Conditions: Hypotension Drug-Induced
Interventions: DRUG: Atenolol Succinate Oral Tablet|DRUG: Metoprolol Succinate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Highland Barley Diet on Glucose Variability in Patients With Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type1 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Highland Barley Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Navigating New Motherhood 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Postpartum Health|Breastfeeding|Contraception|Preventive Care / Anticipatory Guidance|Retention in Care
Interventions: BEHAVIORAL: Patient Navigation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation
Status: RECRUITING
Conditions: Pancreatic Acinar Cell Carcinoma|Pancreatic Adenosquamous Carcinoma|Pancreatic Squamous Cell Carcinoma|Resectable Pancreatic Acinar Cell Carcinoma|Resectable Pancreatic Adenocarcinoma|Resectable Pancreatic Adenosquamous Carcinoma|Resectable Pancreatic Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Olaparib|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis
Status: COMPLETED
Conditions: Chronic Atrophic Gastritis
Interventions: DRUG: Talcid®|DRUG: Chinese medicine prescription|DRUG: Placebo|DRUG: Compound Azimtamide Entieric-coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery
Status: COMPLETED
Conditions: Opioid Free Anaesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Ketamine|DRUG: Fentanyl|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Consitution Of A Biological Collection From Samples From The Gut Microbiote In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine
Status: UNKNOWN
Conditions: Bone and Joint Infection
Interventions: OTHER: BIOLOGICAL COLLECTION FROM THE GUT MICROBIOTE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: P-glypoprotein Inhibition Effect on the Pharmacokinetics of Two Tacrolimus Formulations: Prolonged and Extended-release
Status: UNKNOWN
Conditions: Pharmacokinetics
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treament C|DRUG: Treatment D|BIOLOGICAL: Pharmacocinetik|GENETIC: Genetic|OTHER: Selection visit:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of a High-Protein Diet and/or High-Intensity Training on Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BEHAVIORAL: Sprint Interval Exercise|OTHER: Higher PRO Diet|OTHER: Higher CARB Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cabozantinib S-Malate in Treating Patients With Recurrent or Metastatic Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Adenosquamous Carcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Mixed Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Metastatic Endometrioid Adenocarcinoma|Recurrent Uterine Corpus Cancer|Stage IV Uterine Corpus Cancer AJCC v7|Stage IVA Uterine Corpus Cancer AJCC v7|Stage IVB Uterine Corpus Cancer AJCC v7|Uterine Corpus Carcinosarcoma
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of SS1 (dsFv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-Small Cell Lung Adenocarcinoma
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Adenocarcinoma
Interventions: DRUG: SS1 (dsFv) PE38|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Obese PCOS Patients With LSG vs. Met
Status: ENROLLING_BY_INVITATION
Conditions: Polycystic Ovary Syndrome
Interventions: PROCEDURE: laparoscopic sleeve gastrectomy|DRUG: Metformin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Tranquillization Trial: TREC-India II
Status: COMPLETED
Conditions: Psychotic Disorders|Aggression
Interventions: DRUG: Intramuscular Olanzepine 10 mg|DRUG: Intramuscular Haloperidol 5-10 mg + Promethazine 25-50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Training in Pregnant Women With Gestational Diabetes and Chronic Hypertension
Status: COMPLETED
Conditions: Pregnancy|Gestational Diabetes Mellitus|Chronic Hypertension in Obstetric Context
Interventions: OTHER: Aerobic exercise|OTHER: Stretch exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|GERD|Heartburn
Interventions: DRUG: nizatidine (axid)|DRUG: nizatidine (axid)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: All About Me: An Intervention to Ease the Transition to Long Term Care
Status: NOT_YET_RECRUITING
Conditions: Dementia|Alzheimer Disease|Dementia, Vascular|Dementia, Mixed|Dementia of Alzheimer Type
Interventions: BEHAVIORAL: SAFE at Home
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MP-376 (Aeroquin™, Levofloxacin for Inhalation) in Patients With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Aeroquin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploration of the Optimal Dosage of Cetirizine in the Treatment of Allergic Diseases in Chinese Children
Status: RECRUITING
Conditions: Allergic Disease|Children
Interventions: OTHER: 1-3 Cetirizine Pharmacokinetic samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of AESCULAP Optilene® Mesh Elastic Versus Ethicon Ultrapro® Mesh in Incisional Hernia Repair
Status: COMPLETED
Conditions: Incisional Hernia Repair
Interventions: DEVICE: Mesh Implantation|DEVICE: Mesh Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability Study of a Novel Microbiome Therapeutic in Subjects With Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux
Interventions: DIETARY_SUPPLEMENT: maltosyl-isomalto-oligosaccharides (MIMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide
Status: COMPLETED
Conditions: Overweight|Obesity|Diabetes Mellitus, Type 2
Interventions: DRUG: Tirzepatide|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Improving the Follow up Rate for Pediatric Patients
Status: COMPLETED
Conditions: CNLDO - Congenital Nasolacrimal Duct Obstruction|Amblyopia|Conjunctivitis|Eye Injuries|Corneal Ulcer|Strabismus
Interventions: BEHAVIORAL: Counseling group|BEHAVIORAL: SMS and phone call reminder group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Use of Prostaglandin E1 in Head and Neck Microsurgery
Status: UNKNOWN
Conditions: Microsurgery|Head and Neck|Prostaglandin E1|Thrombosis|Complications
Interventions: DRUG: Prostaglandin E1|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Measurement of Diaphragmatic Thickness in Adolescents With Thoracal Hyperkyphosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hyperkyphosis|Spine Deformity|Diaphragm Issues
Interventions: DIAGNOSTIC_TEST: Thoracal hyperkyphosis study form|DIAGNOSTIC_TEST: Scoliosis graphy|DIAGNOSTIC_TEST: Pulmonary function test|DIAGNOSTIC_TEST: Ultrasonographic Measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Motor Imagery on Trapeziometacarpal Osteoarthritis in Women During the Postoperative Immobilization Period
Status: COMPLETED
Conditions: Osteoarthritis Thumb|Immobilization
Interventions: PROCEDURE: motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outcomes for Patients With SDB and Insufficient Sleep
Status: RECRUITING
Conditions: Sleep Apnea|Insufficient Sleep Syndrome|Sleep|Hypertension
Interventions: BEHAVIORAL: PAP Treatment|BEHAVIORAL: Sleep Education I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ticagrelor Anti Platelet and Pleiotropic Effects in Patients Undergoing Percutaneous Coronary Intervention for an Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Clopidogrel|DRUG: trigagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infusion of a Local Anaesthetic in the Surgical After Modified Radical Mastectomy With Expander
Status: COMPLETED
Conditions: Local Anesthetic
Interventions: DRUG: levo-bupicaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Opioid Free Anesthesia in Bariatric Surgery
Status: COMPLETED
Conditions: Opioid Use|Postoperative Pain|Postoperative Nausea and Vomiting|Bariatric Surgery Candidate
Interventions: DRUG: Opioid free Anesthesia dexmedetomidine and lidocaine|DRUG: Opioid based anesthesia Fentanyl and Remifentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contributions of 3D Photography and Stereophotogrammetry to the Evaluation of Facial Symmetrization by Botulinum Toxin Injections. Study of Facial Symmetry Before and After Botulinum Toxin Injections on the Face of Patients Suffering From Sequellar Peripheral Facial Paralysis
Status: RECRUITING
Conditions: Peripheral Facial Palsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia
Status: COMPLETED
Conditions: Severe Hypertriglyceridemia
Interventions: DRUG: ARO-APOC3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery
Status: COMPLETED
Conditions: Colectomy
Interventions: DRUG: anaesthesia without opiates|DRUG: anaesthesia with morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Acetaminophen for Non-Narcotic Postoperative Pain Management Following Knee Arthroscopy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Intravenous Acetaminophen|DRUG: Placebo (0.9% Normal Saline infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer (CRC)
Interventions: DRUG: Sotorasib|DRUG: Panitumumab|DRUG: Trifluridine and Tipiracil|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
Status: RECRUITING
Conditions: Atypical Alzheimer's Disease|Logopenic Progressive Aphasia (LPA)|Posterior Cortical Atrophy (PCA)|Alzheimer Disease|Alzheimer Disease, Early Onset|Amnestic Disorder|Amnestic Symptoms|Amnestic Mild Cognitive Disorder
Interventions: DRUG: F-18 AV 1451|DRUG: C-11 PiB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: International Validation Study of Sentinel Node Biopsy in Early Cervical Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer
Interventions: PROCEDURE: SLN biopsy only|PROCEDURE: SLN biopsy + PLN dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Use of an Antiemetic to Shorten the Length of Labor in Nulliparous Women
Status: COMPLETED
Conditions: Prolonged First Stage of Labor
Interventions: DRUG: Metoclopramide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture ACL (Anterior Cruciate Ligament)
Status: COMPLETED
Conditions: ACL|ACL Injury|Anterior Cruciate Ligament Injury|Anterior Cruciate Ligament Rupture|Anesthesia
Interventions: OTHER: Acupuncture + Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer's Disease|Huntington's Disease
Interventions: DRUG: Warfarin|DRUG: Dimebon|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMRT With Carboplatin Versus IMRT With Carboplatin and Fluorouracil for Eldly Esophageal Cancer Patients
Status: UNKNOWN
Conditions: Esophageal Cancer|Radiotherapy Side Effect
Interventions: DRUG: Fluorouracil|RADIATION: Intensity modulated radiation therapy|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Soy-Based Meal Replacement in Helping Women With Stage I, Stage II, or Stage III Breast Cancer in Complete Remission Lose Weight
Status: COMPLETED
Conditions: Breast Cancer|Obesity
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|DIETARY_SUPPLEMENT: soy isoflavones|DIETARY_SUPPLEMENT: soy protein isolate|OTHER: counseling intervention|OTHER: educational intervention|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-term, Extension Study of DS-5141b in Patients With Duchenne Muscular Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: DS-5141b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Carboplatin/Paclitaxel in Combination With ABT-869 in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: ABT-869|DRUG: Placebo for ABT-869|DRUG: ABT-869|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chidamide for Patients With Recurrent and Metastatic Epstein-Barr Virus (EBV)-Associated Solid Tumors
Status: UNKNOWN
Conditions: Experimental Tumor
Interventions: DRUG: Chidamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Apremilast (CC-10004) in Subjects With Moderate-to-Severe Plaque-Type Psoriasis (Core Study)
Status: COMPLETED
Conditions: Psoriasis|Plaque-type Psoriasis
Interventions: DRUG: Apremilast 10mg|DRUG: Apremilast 20mg|DRUG: Apremilast 30 mg|DRUG: Placebo|DRUG: Apremilast 30mg|DRUG: Apremilast 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of HR20013 for Injection in Patients With Malignant Solid Tumors
Status: COMPLETED
Conditions: Prevention of Nausea and Vomiting Caused by Highly Emetogenic Chemotherapy
Interventions: DRUG: HR20013 for injection；dexamethasone|DRUG: fosaprepitant dimeglumine for injection；palonosetron hydrochloride injection；dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: S9922 Combination Chemo Plus Filgrastim With or Without Thalidomide in Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: dexamethasone|DRUG: etoposide|DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Hypoxia Measured in F-Miso PET/Scan and MRI in Patients With Squamous Cells Carcinoma
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Oropharynx
Interventions: DRUG: F-Miso PET scan coupled with MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase II Study of Bevacizumab, Irinotecan and Capecitabine in Patients With Previously Untreated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Include Asthma Chronic Obstructive Pulmonary Disease (COPD) Overlap Patients.Patients Were Vitamin D Deficient.Age Range 40-70 Years, Smokers.Patients Were Advised to Take Either Placebo or Vitamin D3.Lung Functions and Exercise Tolerance Were Assessed at Baseline and at 26th Weeks.
Status: COMPLETED
Conditions: Asthma-COPD Overlap Syndrome
Interventions: DRUG: Cholecalciferol|OTHER: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Various Bariatric Surgical Procedures on Intestinal TRL Metabolism in Obese Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Obesity|Diabetes
Interventions: OTHER: stable isotope enrichment methodology (5,5,5-D3-L-Leucine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: S0114 Vaccine Therapy in Treating Patients With Gastric, Prostate, or Ovarian Cancer
Status: TERMINATED
Conditions: Brain Tumors|Gastric Cancer|Ovarian Cancer|Prostate Cancer
Interventions: BIOLOGICAL: KLH|BIOLOGICAL: GMCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Signatures of Processing the Temporal Features of Auditory Events: From Preterm Infancy to Adulthood
Status: RECRUITING
Conditions: Time Perception|EEG|Premature Neonates|Discrimination
Interventions: PROCEDURE: EEG|PROCEDURE: NIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Local Infusion of Ropivacaine for Post-Op Pain Control After Osseocutaneous Free Flaps
Status: COMPLETED
Conditions: Head and Neck Cancer|Free Tissue Transfer
Interventions: DRUG: Ropivicaine|DRUG: Local Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Assess the Effectiveness of Educational Outreach in Prescription Guidelines
Status: UNKNOWN
Conditions: Inflammation|Gastroesophageal Reflux|Gastrointestinal Diseases|Cardiovascular Diseases
Interventions: BEHAVIORAL: Educational Outreach Visits|OTHER: Passive Dissemination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis.
Status: WITHDRAWN
Conditions: Refractory Ascites in Children With Cirrhosis
Interventions: DRUG: Midodrine|OTHER: Standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Evaluate the Use of the RxSight Light Adjustable Lens (LAL) and the Light Delivery Device (LDD) to Improve Visual Outcomes
Status: COMPLETED
Conditions: Aphakia|Cataract
Interventions: DEVICE: Light Adjustable lens (LAL) and Light Delivery Device (LDD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MIT-001 for Prevention of CCRT-Induced OM in HNSCC Patients
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Oral Mucositis
Interventions: DRUG: MIT-001 plus CCRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CARDINAL Adjustable Annuloplasty Ring System For Treatment of Mitral Regurgitation
Status: COMPLETED
Conditions: Mitral Valve Insufficiency
Interventions: DEVICE: Adjustable Annuloplasty Ring with option to adjust off pump.|DEVICE: Device: Adjustable Annuloplasty Ring (with option to adjust off-pump)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening for Synchronous Metastases in Colorectal Cancer With DW-MRI (SERENADE)
Status: RECRUITING
Conditions: Colorectal Neoplasms|Neoplasm Metastases|Hepatic Neoplasms
Interventions: OTHER: Diffusion Weighted MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Effectiveness of Topical Autologous Platelet Gel for the Treatment of Venous Ulcers
Status: WITHDRAWN
Conditions: Venous Ulcer
Interventions: PROCEDURE: Autologous Platelet Gel (APG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up
Status: COMPLETED
Conditions: Non ST Elevation Myocardial Infarction
Interventions: DRUG: Eptifibatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between U\S Guided Erector Spinaeblock and Paravertebral Block on Acute and Chronic Post Mastectomy Pain
Status: RECRUITING
Conditions: Comparison Between Ultrasound Guided Erector Spinae Plane Block and Para-vertebral Block on Acute and Chronic Post Mastectomy Pain
Interventions: PROCEDURE: ultrasound guided erector spinae plane block with bupivacaine 0.25% And ultrasound guided Paraveretebral block with bupivacaine 0.25 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: FDG-PET Directed Treatment in Improving Response in Patients With Locally Advanced Stomach or Gastroesophageal Junction Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Gastric Adenocarcinoma|Gastric Cancer
Interventions: PROCEDURE: FDG-PET|PROCEDURE: surgery|DRUG: 5-FU|DRUG: capecitabine|DRUG: docetaxel|DRUG: Irinotecan|RADIATION: 3D-CRT|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gastric Emptying on Blood Glucose Profile of Type 1 Diabetes Mellitus and Its Therapeutic Strategies
Status: RECRUITING
Conditions: Diabetes
Interventions: DRUG: insulin injection 15 minutes before meals|DRUG: Insulin injection 15 minutes after eating
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)
Status: COMPLETED
Conditions: Urinary Tract Infections|Pyelonephritis
Interventions: DRUG: Relebactam 250 mg|DRUG: Relebactam 125 mg|DRUG: imipenem/cilastatin 500 mg|DRUG: Placebo to relebactam|DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of the Xue-Fu-Zhu-Yu Capsule in Treatment of Qi Stagnation and Blood Stasis Syndrome.
Status: COMPLETED
Conditions: Qi Stagnation and Blood Stasis Syndrome
Interventions: DRUG: xue-fu-zhu-yu capsule|DRUG: xue-fu-zhu-yu capsule simulated agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening Programme for Abdominal Aortic Aneurysm by Hand-Held-Ultrasonography in Primary Health Care
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Ultrasound (Trademark:VScan; Manufacturer:General Electric)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis Atopic
Interventions: DRUG: Amlitelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract Infection
Status: NO_LONGER_AVAILABLE
Conditions: Complicated Urinary Tract Infection|Acute Pyelonephritis
Interventions: DRUG: Sulopenem Etzadroxil/Probenecid
Study Type: EXPANDED_ACCESS
Clinical trial: Effects of Dietary and Weight Management on Pregnancy Outcomes in Mobile Medical Platform
Status: UNKNOWN
Conditions: Gestational Diabetes Mellitus|Hypertensive Disorder of Pregnancy
Interventions: BEHAVIORAL: Intensive dietary and weight management|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder|Dissociation|Maternal Care Patterns|Infant Behavior|Maternal Behavior|Maternal Distress|Mood Disturbance|Emotional Regulation
Interventions: DEVICE: Neurofeedback (MUSE 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph1 Study of Valortim and Doxycycline in Humans
Status: TERMINATED
Conditions: Anthrax
Interventions: DRUG: Doxycycline and Valortim|DRUG: Placebo Antibiotic and Valortim|DRUG: Placebo Antibiotic and Placebo Valortim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Light-Activated Talaporfin Sodium in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: talaporfin sodium|DEVICE: Transurethral illumination with light emitting diodes|PROCEDURE: Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Romosozumab Treatment in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Romosozumab|DRUG: Placebo|DRUG: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Network to Calculate Morphology of the Cleft Palate to Reduce Cleft Lip and Palate Treatment Burden.
Status: RECRUITING
Conditions: Cleft Palate|Orofacial Cleft
Interventions: OTHER: data collection of palatal casts and palatal images of cleft patients routinely treated at the institution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intra-articular Pulsed Radiofrequency in Osteoarthritis
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DEVICE: pulsed radiofrequency (Neurotherm NT1000, Neurotherm Inc., USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT