pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Parental Participation on the Neonatal Ward - the neoPARTNER Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature|Premature Birth|Prematurity|Perinatal Problems|Neonatal Sepsis|Neonatal Infection|Neonatal Hyperbilirubinemia|Infant Development|Infant, Newborn, Disease|Infant, Premature, Diseases|Infant, Small for Gestational Age|Small for Gestational Age Infant|Maternal Distress|Parent-Child Relations|Parents
Interventions: OTHER: Family Integrated Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I/II Study of XELOXIRI and Bevacizumab as First-line Treatment in Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Cancer|Colorectal Cancer|Colorectal Adenocarcinoma
Interventions: DRUG: XELOXIRI/Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Citrulline on Gut Functioning During Excercise
Status: UNKNOWN
Conditions: Gastrointestinal|Hypoperfusion|Gut Damage
Interventions: DIETARY_SUPPLEMENT: Citrulline|DIETARY_SUPPLEMENT: alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Acute Promyelocytic Leukemia
Status: APPROVED_FOR_MARKETING
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Promyelocytic Leukemia (M3)|Childhood Acute Promyelocytic Leukemia (M3)|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: DRUG: gemtuzumab ozogamicin|OTHER: laboratory biomarker analysis
Study Type: EXPANDED_ACCESS
Clinical trial: The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Cariprazine|DRUG: Placebo|DRUG: Antidepressant Therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: XELOX Combined With Cadonilimab Versus XELOX as Neoadjuvant Treatment for Locally Advanced, pMMR Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer|MSS
Interventions: DRUG: Cadonilimab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Conducted to Capture Patients With Diabetic Retinopathy in General Practitioners, Using SW as Medical Device
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: SW as medical devices(comperator) to evaluate the retinal image of the patient's eye (to identify if the patient has DR or if the patient is healthy) .
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Trial of Etoricoxib (Arcoxia) Taken Prophylactically to Prevent Ramadan Headache
Status: COMPLETED
Conditions: Headache|Fasting|Fasting Headache|Ramadan Headache
Interventions: DRUG: Etoricoxib|DRUG: Etoricoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Standard Versus Fanning Techniques for Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA)
Status: COMPLETED
Conditions: Pancreatic Tumors
Interventions: PROCEDURE: Standard|PROCEDURE: Fanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Biaxin, Revlimid, and Dexamethasone for Untreated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Clarithromycin, Lenalidomide, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Super-hyperfractionation Pulse Radiotherapy Combined With ICIs for Advanced NSCLC
Status: RECRUITING
Conditions: Lung Cancer|Immune Checkpoint Inhibitor|Radiotherapy
Interventions: RADIATION: Super-hyperfractionation Pulse Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Dexmedetomidine Premedication in Children
Status: COMPLETED
Conditions: Preoperative Sedation
Interventions: DRUG: Midazolam|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: R21/Matrix-M1|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Open Loop DBS|DEVICE: Adaptive (Closed Loop) DBS|DEVICE: Intermittent Open Loop DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interval Training Versus Electro Acupuncture on Liver Functions in Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: aerobic interval training exercise .|DEVICE: electro acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC)
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy (DCM)|Ischemic Cardiomyopathy|Nonischemic Cardiomyopathy|Heart Failure
Interventions: BIOLOGICAL: Allogeneic Cardiosphere-Derived Cells (CDCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Training Software (SJ-RS-WL2015) Rehabilitating Intermittent Exotropia Binocular Functions
Status: UNKNOWN
Conditions: Intermittent Exotropia
Interventions: OTHER: SJ-RS-WL2015 visual training program software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ZIO-201-T in Combination With Doxorubicin in Solid Tumors
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: ZIO-201-T and doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Decitabine (ASTX727) and Durvalumab in Recurrent and/or Metastatic Head and Neck Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Oral Decitabine|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Decitabine and Cytarabine for Older Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: decitabine and cytarabine|OTHER: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Couple Treatment for Gambling/Substance Use Disorder
Status: RECRUITING
Conditions: Gambling Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Integrative Couple Treatment for Addiction (ICT-A)|BEHAVIORAL: Treatment individual as usually offered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine（Hecolin®）
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: Recombinant (E. Coli) Hepatitis E Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Chemotherapy in Metastatic or Recurrent Carcinoma Cervix
Status: UNKNOWN
Conditions: Metastatic Carcinoma to the Uterine Cervix|Recurrent Carcinoma Cervix|Cervix Carcinoma Recurrent
Interventions: DRUG: Paclitaxel and carboplatin|DRUG: Paclitaxel and carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ruling Out Pulmonary Embolism During Pregnancy:a Multicenter Outcome Study
Status: COMPLETED
Conditions: Pulmonary Embolism|Deep Vein Thrombosis
Interventions: OTHER: Pregnant patients with suspected PE will undergo a strategy based on clinical probability assessment, D-dimer, lower limb vein ultrasonography and MSCT.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients With Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS)
Status: RECRUITING
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Betamethasone Dipropionate Nasal Cream 0.0644%|DEVICE: Pre-filled syringe and applicator device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults With Thalassemia
Status: UNKNOWN
Conditions: Thalassemia|Iron Overload
Interventions: DIETARY_SUPPLEMENT: Meal matrix with polyphenol supplement (PPS)|DIETARY_SUPPLEMENT: Meal matrix with placebo|DIETARY_SUPPLEMENT: No meal matrix with PPS|DIETARY_SUPPLEMENT: No meal matrix with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)
Status: RECRUITING
Conditions: Non-muscle Invasive Bladder Cancer|NMIBC|Carcinoma in Situ of Bladder|Bladder Cancer|Urothelial Carcinoma Bladder|Urothelial Carcinoma Recurrent
Interventions: DRUG: UGN-301|DRUG: UGN-201|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Recovery of Moods, Opioids, and Pain Trial (PROMPT)
Status: COMPLETED
Conditions: Opioid Cessation
Interventions: BEHAVIORAL: Motivational Interviewing and Physician Guided Opioid Weaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biologic Tapering Study of TNF Inhibitors in Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Axial Spondyloarthritis
Interventions: DRUG: Tapered doses of TNFi|DRUG: Standard dose of TNFi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Different Sedative Medications in Monitored Anesthesia Care During Eye Surgery With Local Anesthesia
Status: UNKNOWN
Conditions: Balanced Anesthesia|Adjuvants,Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy in Ablative Fractional Laser Assisted Photodynamic Therapy According to Ablative Depth for Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Dermatosis
Interventions: DRUG: lidocaine/prilocaine (5%) application|DEVICE: 2940-nm Er:YAG AFL pretreatment|DRUG: MAL application|OTHER: Measurements of the fluorescence intensity|DEVICE: irradiation with red light-emitting diode lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to Two HIV Vaccine Formulations (rMVA-HIV and rFPV-HIV) Alone or in Combination in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: rMVA-HIV (rMVA-HIV env/gag + rMVA-HIV tat/rev/nef-RT)|BIOLOGICAL: rFPV-HIV (rFPV-HIV env/gag + rFPV-HIV tat/rev/nef-RT)|BIOLOGICAL: Empty TBC-FPV|BIOLOGICAL: rMVA-HIV (rMVA-HIV env/gag + rMVA-HIV tat/rev/nef-RT)|BIOLOGICAL: rMVA-HIV (rMVA-HIV env/gag + rMVA-HIV tat/rev/nef-RT)|BIOLOGICAL: TBC-MVA and TBC-FPV|BIOLOGICAL: TBC-MVA and TBC-FPV|BIOLOGICAL: TBC-MVA and TBC-FPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Efficacy and Safety Study of Azacitidine Subcutaneous in Combination With Durvalumab (MEDI4736) in Previously Untreated Adults With Higher-Risk Myelodysplastic Syndromes (MDS) or in Elderly Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine|BIOLOGICAL: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation of Pulmonary Tumors Response Evaluation
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Pulmonary Metastases
Interventions: DEVICE: RF ablation (Rita Medical Systems Model 1500x)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Hip Activation Compared to Hip Plus Balance Training on the Forward-Step-Down Test
Status: ACTIVE_NOT_RECRUITING
Conditions: Control of Frontal Plane Biomechanics|Patellofemoral Pain Syndrome
Interventions: OTHER: Hip Activation|OTHER: Hip activation + Single leg balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mesh Position and Outcomes Following Inguinal Hernia Repair Using an MRI Visible Hernia Mesh
Status: TERMINATED
Conditions: Unilateral Simple Inguinal Hernia
Interventions: DEVICE: DynaMesh visible mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Disilicate Glass-ceramic Versus Hybrid Ceramic Superstructure Materials on Implant Stability
Status: COMPLETED
Conditions: Prosthesis Survival
Interventions: OTHER: Vita Enamic (hybrid dental ceramic)|OTHER: lithium disilicate glass-ceramic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Of Prevention of Chemo-Induced Nausea and Vomiting Caused By Moderately Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Nausea and Vomiting, Chemotherapy-Induced|Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: GW679769|DRUG: Dexamethasone|DRUG: Ondansetron Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial
Status: COMPLETED
Conditions: Central Neuropathic Pain|Allodynia|Spinal Cord Injury
Interventions: DRUG: Dextromethorphan|DRUG: Lidocaine|DRUG: Placebo (Dextromethorphan)|DRUG: Placebo (Lidocaine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endocrine Outcome of Surgery for Pituitary Adenoma
Status: TERMINATED
Conditions: Pituitary Adenoma
Interventions: PROCEDURE: Endoscopic resection|PROCEDURE: Microsurgical resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Preservation Versus Excision of Denonvilliers Fascia in L-PANP Surgery
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: Preservation of Denonvilliers Fascia|PROCEDURE: Excision of Denonvilliers Fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INST Phase II Trial of Gemcitabine and Irinotecan in Patients With Relapsed or Refractory Lymphoma.
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Cancer
Interventions: DRUG: Gemcitabine, Irinotecan, Allopurinol.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3079514 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: LY3079514|DRUG: LY3079514|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Micro-dosing Indocyanine Green (ICG) in Children
Status: RECRUITING
Conditions: Perfusion|Fluorescence Imaging|Gastrointestinal Tract Disorders|Genitourinary Disease
Interventions: DRUG: Indocyanine Green (ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Do Ketone Drinks Improve Immune, Metabolic and Cognitive Health in Older Adults
Status: RECRUITING
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Ketone drink|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ABLATE WEIGHT 2 (Single-Stage Fundic Ablation Plus ESG for Weight Loss)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Fundic Ablation in Combination with Endoscopic Sleeve Gastroplasty|DEVICE: Fundic Mucosal Ablation with ERBE HybridAPC|DEVICE: Apollo ESG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Study GSP 301 in Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: GSP 301-1 NS (QD)|DRUG: GSP 301-2 NS (BID)|DRUG: GSP 301 Placebo NS|DRUG: Olopatadine HCl-1 NS (QD)|DRUG: Olopatadine HCl-2 NS (BID)|DRUG: Mometasone Furoate-1 NS (QD)|DRUG: Mometasone Furoate-2 NS (BID)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Exercise Training Dose on Exercise Performance and Noninvasively Estimated Muscle Oxygen Extraction in Diabetic Postmenopausal Women
Status: UNKNOWN
Conditions: Postmenopausal Diabetes
Interventions: OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and PK of Nintedanib in Combination With Pirfenidone in IPF
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Nintedanib|DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formulations of Fluoridated Toothpastes With and Without Post-brushing Water Rinsing.
Status: COMPLETED
Conditions: Caries
Interventions: OTHER: Sodium fluoride toothpaste 1,450 ppmF|OTHER: sodium monofluorophosphate toothpaste 1,450 ppmF|OTHER: stannous fluoride combined with sodium fluoride toothpaste 1,450 ppmF|OTHER: sodium fluoride combined sodium monofluorophosphate toothpaste 1,450 ppmF|OTHER: Amine fluoride toothpaste 1,400 ppmF|OTHER: Non-fluoridated toothpaste 0 ppmF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Natural Killer, Complement and T-lymphocytes in COVID-19 Disease, a Prospective Monocentric Study
Status: UNKNOWN
Conditions: Complement Abnormality|Peripheral Blood Mononuclear Cells|Covid19
Interventions: OTHER: Blood analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Subjects Aged 65 Years and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: High-dose quadrivalent influenza virus vaccine|BIOLOGICAL: High-dose influenza virus vaccine|BIOLOGICAL: High-dose trivalent inactivated influenza vaccine|BIOLOGICAL: High-dose trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Deep Phenotyping of Bone Disease in Type 2 Diabetes and Relations to Diabetic Neuropathy
Status: RECRUITING
Conditions: Type 2 Diabetes|Bone Disease|Osteoporosis|Diabetic Neuropathy Peripheral|Autonomic Neuropathy, Diabetic
Interventions: DIAGNOSTIC_TEST: Dual Energy X-ray Absorbtiometry scan|DIAGNOSTIC_TEST: High-resolution peripheral quantitative computed tomography|DIAGNOSTIC_TEST: Microindentation|DIAGNOSTIC_TEST: Thermal perception thresholds|DIAGNOSTIC_TEST: Nerve conduction studies|DIAGNOSTIC_TEST: Composite Autonomic Symptom Score 31|DIAGNOSTIC_TEST: Skin biopsies with quantification of intra-epidermal nerve fibre density|DIAGNOSTIC_TEST: Perception Threshold Tracking|DIAGNOSTIC_TEST: Assessment of cardiovascular autonomic neuropathy|DIAGNOSTIC_TEST: Handgrip strength|DIAGNOSTIC_TEST: Force plate platform|DIAGNOSTIC_TEST: Biospecimen collection|DIAGNOSTIC_TEST: Isometric leg extension strength|DIAGNOSTIC_TEST: Michigan Neuropathy Screening Instrument
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long or Very Long-Limb Gastric Bypass in Superobese
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: laparoscopic gastric Roux-en-Y gastric bypass|PROCEDURE: laparoscopic gastric Roux-en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases
Status: COMPLETED
Conditions: Metastasis to Bone|Radiotherapy|Neoplasm Metastasis
Interventions: RADIATION: Stereotactic body radiotherapy|RADIATION: 3D-conformal radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lymphaticovenous Anastomosis as Treatment for Lymphedema
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Lymphedema|Secondary Lymphedema|Iatrogenic Lymphedema|Lymphedema|Lymphedema of Upper Limb|Lymphedema Arm|Lymphedema, Breast Cancer|Breast Neoplasm|Neoplasms|Breast Cancer|Breast Diseases|Lymphatic Diseases|Skin Diseases|Postoperative Complications|Pathologic Processes|Anastomose|Surgery|Surgical; Lymphedema, Postmastectomy|Postmastectomy Lymphedema|Postmastectomy Lymphedema Syndrome Left Upper Limb|Postmastectomy Lymphedema Syndrome Right Upper Limb|Postmastectomy Lymphedema Syndrome
Interventions: PROCEDURE: Lymphovenous anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and BCG Solution in Treating Patients With Recurrent Non-Muscle-Invasive Bladder Cancer
Status: COMPLETED
Conditions: Recurrent Bladder Carcinoma|Stage 0a Bladder Urothelial Carcinoma|Stage 0is Bladder Urothelial Carcinoma|Stage I Bladder Cancer
Interventions: BIOLOGICAL: BCG Solution|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of F. Prausnitzii on Glycemic Control
Status: UNKNOWN
Conditions: Pre Diabetes|Impaired Glucose Tolerance|Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: F. prausnitzii and D. piger|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Aspen Spinous Process Fixation System and PLIF Technique for the Treatment of Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain|Spondylolisthesis|Spondylosis|Spinal Instability|Spinal Stenosis
Interventions: DEVICE: PLIF and Aspen (spinous process fixation device)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Text2Connect, Component 2 of iCHART (Integrated Care to Help At-Risk Teens)
Status: COMPLETED
Conditions: Depression|Suicidal Ideation
Interventions: BEHAVIORAL: Text2Connect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparative Study of Glidescope Versus Macintosh Laryngoscope in Adult Hypertensive Patients
Status: COMPLETED
Conditions: Hypertensive Patients
Interventions: DEVICE: Glidescope|DEVICE: Macintosh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Walking Interventions, Cognitive Remediation and Mild Cognitive Impairment
Status: TERMINATED
Conditions: Cognitive Impairment
Interventions: BEHAVIORAL: Cognitive Remediation Therapy Group|BEHAVIORAL: Walking Intervention (WI) Group|BEHAVIORAL: Combination Group|BEHAVIORAL: Healthy Living Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Etoposide, Filgrastim, and Plerixafor in Improving Stem Cell Mobilization in Treating Patients With Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Adult Acute Lymphoblastic Leukemia in Remission|Adult Grade III Lymphomatoid Granulomatosis|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Hepatosplenic T-cell Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|T-cell Large Granular Lymphocyte Leukemia|Testicular Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: plerixafor|BIOLOGICAL: filgrastim|DRUG: etoposide|PROCEDURE: leukapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Leflunomide and Azathioprine for the Maintenance Therapy of ANCA Associated Vasculitis
Status: RECRUITING
Conditions: ANCA Associated Vasculitis|Maintenance Therapy
Interventions: DRUG: Leflunomide|DRUG: Azathioprine Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding and Expansion Study of RO7051790 Administered Orally in Participants With Relapsed, Extensive-Stage Disease Small Cell Lung Cancer (ED SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: RO7051790
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological Investigations of Movement Disorders
Status: COMPLETED
Conditions: Parkinson's Disease|Tourette's Syndrome|Tic Disorders|Dystonia|Movement Disorders
Interventions: PROCEDURE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Eye-tracking Device|DEVICE: Pulsed vibrator|OTHER: Gait Trainer Treadmill (GTT)|OTHER: Standard psychiatric scales SCID-I, YBOCS and SCI-OBS-lifetime and cognitive scales MMSE and MOCA|DEVICE: iMobility|DEVICE: QMAT|DIAGNOSTIC_TEST: Treadmill Test|DEVICE: Arm Intellistretch Device|PROCEDURE: Transcranial Sonography (TCS)|OTHER: Behavioral tasks|PROCEDURE: TMS single/paired pulse|PROCEDURE: MEG|PROCEDURE: EEG|PROCEDURE: MRI techniques|PROCEDURE: Peripheral Nerve Stimulation|PROCEDURE: EMG|PROCEDURE: Trancutaneous spinal direct current stimulation (tsDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metabolic Abnormalities in Hispanic Children With Cystic Fibrosis
Status: WITHDRAWN
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: Oral Glucose tolerance test|PROCEDURE: Whole body protein turnover|PROCEDURE: IV glucose tolerance test|PROCEDURE: Indirect Calorimetry|PROCEDURE: Dual Energy X-ray Absorptiometry (DEXA)|PROCEDURE: Growth Hormone Stimulation Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of CD147-targeted CAR-T by Hepatic Artery Infusions for Very Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: BIOLOGICAL: CD147-CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Cholecystectomy Gall Bladder Remnant and Cystic Duct Stump Stone
Status: COMPLETED
Conditions: Laparocele
Interventions: PROCEDURE: open completion cholecystectomy|PROCEDURE: lap completion cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)
Status: COMPLETED
Conditions: Treatment Resistant Depression|Nitrous Oxyde
Interventions: DRUG: Nitrous Oxide-Oxygen|DEVICE: Tissue Pulsatility Imaging - TPI|DEVICE: Magnetic Resonance Imaging - MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AF Ablation Based on High Density Voltage Mapping and CFAE
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: pulmonary vein isolation|PROCEDURE: Low-Voltage & CFAE guided ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Autologous Platelet Rich Plasma on Posterior Lumbar Interbody Fusion
Status: UNKNOWN
Conditions: Autologous Platelet Rich Plasma Effect on Bone Healing
Interventions: BIOLOGICAL: autologous platelet rich plasma|PROCEDURE: posterior lumbar interbody fusion without autologous platelet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of S-1 and Oxaliplatin (SOX) Versus Capecitabine and Oxaliplatin (COX) in Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: S-1 & Oxaliplatin|DRUG: Capecitabine & Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Juice Study: Sensitivity of Skin Carotenoid Status to Detect Change in Intake
Status: COMPLETED
Conditions: Overweight
Interventions: OTHER: High dose vegetable juice|OTHER: Medium dose vegetable juice|OTHER: Low dose vegetable juice|OTHER: Control bottled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of R-ACVBP Regimen Supported by Pegfilgrastim in High-Risk Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Untreated CD20-positive Large B-cell Lymphoma
Interventions: DRUG: Rituximab + ACVBP regimen plus Pegfilgrastim|PROCEDURE: Autologous stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combine With Raltitrexed Versus Radiotherapy Alone in Older Patients With HNSCC.
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Raltitrexed|RADIATION: Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Printed Implants for the Defect Reconstruction in Patients With Chest Wall Tumors
Status: RECRUITING
Conditions: Tumor of Bone|Chest Wall Tumor|Chest Wall Sarcoma|Sarcoma of Bone|Surgery|Implant Site Reaction
Interventions: DEVICE: Implants|DEVICE: Plates
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of CTP-543 and Oral Contraceptives in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CTP-543|DRUG: Combined oral contraceptive containing Ethinyl estradiol (EE) and Levonorgestrel (LNG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Left Atrium Substrate Based Ablation Plus Circumferential Pulmonary Vein Isolation to Treat Chronic Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: radiofrequency catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neo-adjuvant RO7009789 Alone or Neo-adjuvant RO7009789 Plus Nab-Paclitaxel and Gemcitabine Followed by Adjuvant RO7009789 Plus Nab-Paclitaxel and Gemcitabine for Patients With Newly Diagnosed Resectable Pancreatic Carcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: RO70097890|DRUG: nab-paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Kinesio Taping on Pain, Range of Motion, and Functional Performance in People With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Elastic tape ( kinesio tape)|OTHER: Sham Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diagnostics and Therapy of Disease-Related Quality of Life of Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BEHAVIORAL: physio,pain,psychotherapy;social,nutrit.counselling&sports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Kansas City Community Environmental Remediation And Training (KC CERT)
Status: TERMINATED
Conditions: Asthma|Rhinitis|Allergy
Interventions: BEHAVIORAL: Basic home repair|BEHAVIORAL: Asthma Trigger Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease
Status: COMPLETED
Conditions: Charcot-Marie-Tooth Disease, Type IA
Interventions: BEHAVIORAL: Falls management plus exercise training|BEHAVIORAL: Falls management only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pyridorin in Diabetic Nephropathy
Status: TERMINATED
Conditions: Diabetic Nephropathy|Diabetic Kidney Disease
Interventions: DRUG: Pyridorin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trimethylamine N-oxide Effects of a Pomegranate Supplement Simultaneously With Carnitine (TESSA)
Status: ENROLLING_BY_INVITATION
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: L-carnitine + Pomegranate extract|DIETARY_SUPPLEMENT: L-carnitine + Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Pharmacokinetic Interaction Between Celecoxib and Rebamipide
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Celecoxib|DRUG: Rebamipide|DRUG: Celecoxib plus Rebamipide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Efficacy and Safety of JTT-251 in Participants With Pulmonary Arterial Hypertension
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: JTT-251|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: AIDS-Related Hodgkin Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Waldenstrom Macroglobulinemia
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study in Healthy Volunteers of the Safety and Metabolism of Different Doses of the Anti-HIV Drug TMC278LA.
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: 300mg TMC278LA|DRUG: 150mg TMC278LA|DRUG: 1200mg TMC278LA|DRUG: 600mg TMC278LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fruit and Vegetable Juice Concentrate Effects on RBP4 and Antioxidant Capacity in Lean and Overweight 6-10 Year Old Boys
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Fruit and Vegetable Juice Concentrate (FVJC)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Surveillance in Serrated Polyposis Syndrome and Low-risk of Advanced Neoplasia
Status: UNKNOWN
Conditions: Colonic Polyp|Colonic Neoplasms|Colonic Cancer|Serrated Polyposis|Serrated Polyp of Colon
Interventions: PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Whey Protein Study - Identification of Sustainable Satiety
Status: COMPLETED
Conditions: Satiety
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: HPL|DIETARY_SUPPLEMENT: LPL|DIETARY_SUPPLEMENT: HPS|DIETARY_SUPPLEMENT: LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ketamine Treatment of Youth Suicide Attempters
Status: RECRUITING
Conditions: Suicide, Attempted
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Saline|BEHAVIORAL: CAMS Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sustained Release d-Amphetamine on Choice Between Cocaine and a Non-Drug Reinforcer
Status: COMPLETED
Conditions: Active Cocaine Users
Interventions: DRUG: Cocaine|DRUG: Sustained Release d-Amphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PALbociclib Endocrine Therapy Followed by Talazo vs. Talazoz-Atezo Study
Status: NOT_YET_RECRUITING
Conditions: Premenopausal HR+/HER2- Metastatic Breast Cancer
Interventions: DRUG: Pabociclib, Endocrine, Talazoparib, Atezolizumab|DRUG: Pabociclib, Endocrine, Talazoparib,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of ICG Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
Status: RECRUITING
Conditions: Thyroid Diseases
Interventions: DRUG: ICG|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Learn How BAY1817080 Moves Into, Through and Out of the Body and How Safe it is in Healthy Chinese Men
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BAY1817080|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Akathisia in Post Operative Outpatients Surgery
Status: COMPLETED
Conditions: Akathisia
Interventions: DRUG: Droperidol 1,25 mg administration, Droperidol 0,625 mg administration, Odansetron 4 mg administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of GR2002 Injection in Patients With Atopic Dermatitis.
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: GR2002 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Adagrasib and Durvalumab for Treatment of Advanced Non-small Cell Lung Cancers and Gastro-intestinal Cancers Harboring KRAS G12C Mutations
Status: WITHDRAWN
Conditions: Lung Cancer|Gastro-intestinal Cancer
Interventions: DRUG: Durvalumab|DRUG: Adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy of Peginesatide for Treatment of Anemia in Participants on Dialysis Not Receiving an ESA
Status: COMPLETED
Conditions: Anemia|Chronic Renal Failure|Chronic Kidney Disease
Interventions: DRUG: peginesatide|DRUG: peginesatide|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Ferulic Acid Bioavailability in Bran
Status: COMPLETED
Conditions: Healthy Males
Interventions: OTHER: ferulic acid|DIETARY_SUPPLEMENT: Treated bran bread|DIETARY_SUPPLEMENT: wholegrain bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of AVP-923 in PBA Patients With ALS or MS
Status: COMPLETED
Conditions: Pseudobulbar Affect (PBA)
Interventions: DRUG: dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg|DRUG: dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short Segment vs Long Segment Fixation in Traumatic Dorsolumbar Spine Fractures
Status: COMPLETED
Conditions: SPINAL Fracture
Interventions: PROCEDURE: short segment posterior spine fixation|PROCEDURE: long segment posterior spine fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Ethambutol hydrochloride|DRUG: Rifabutin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT