pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Acute Exposure to High Altitude on Heart Rate and Ventilation During Exercise
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Assessment at Low Altitude (470m above sea level)|OTHER: Exposure to High Altitude (2500m above sea level)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Moderate and Severe Plaque Psoriasis
Interventions: DRUG: Placebo|DRUG: AEB071
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Infrared Diode Laser on Improvement of Scar and Prevention of Recurrence of Excised Keloid
Status: UNKNOWN
Conditions: Keloid|Surgical Scar
Interventions: DEVICE: infra-red diode laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Orthotics, Pain & Fear of Falling
Status: COMPLETED
Conditions: Foot Pain|Foot Functionality|Fear of Falling
Interventions: DEVICE: Aetrex L2305 Premium Memory Foam Orthotics W/ Metatarsal Support|DEVICE: Aetrex L2300 Premium Memory Foam Orthotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Acalabrutinib|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Crossover Study to Evaluate the Efficacy of Simvastatin in Elevating HDL-C Levels in Patients With Type 2 Diabetes (0733-216)(COMPLETED)
Status: COMPLETED
Conditions: HDL Cholesterol
Interventions: DRUG: MK0733 / Duration of Treatment: 18 Weeks|DRUG: Comparator: placebo (unspecified) / Duration of Treatment: 18 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis
Status: COMPLETED
Conditions: Severe Acute Pancreatitis
Interventions: PROCEDURE: Epidural anesthesia|DRUG: Patient controlled intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Therapeutic Sailing (MBTS) Versus Standard Recreation Therapy Activity (SRT)
Status: WITHDRAWN
Conditions: Psychiatric Disorder|Substance Use Disorders
Interventions: BEHAVIORAL: Mindfulness-based Therapeutic Sailing (MBTS) versus a standard recreation therapy activity, bowling, (SRT).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Hamstring Stretching Using Pressure Biofeedback Unit in Patients With Low Back Pain.
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: OTHER: Hamstring stretching with Pressure Biofeedback Unit|OTHER: Hamstring stretching with out Pressure Biofeedback Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Independent Weight Loss Maintenance for Communities With Arthritis in North Carolina: the I-CAN Clinical Trial
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: BEHAVIORAL: Weight-Loss Maintenance|BEHAVIORAL: Health Education (Attention Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Salvinorin A in Healthy Controls
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Salvinorin A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Practice Experiences for School Reintegration
Status: ENROLLING_BY_INVITATION
Conditions: Suicide
Interventions: BEHAVIORAL: Safety Planning|BEHAVIORAL: VR Enhanced Affect Regulation|BEHAVIORAL: VR Enhanced Cognitive Restructuring|BEHAVIORAL: VR Enhanced Problem Solving|BEHAVIORAL: Cognitive Behavioral Therapy (CBT) Worksheets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes, Gestational|PreDiabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia.
Status: UNKNOWN
Conditions: Endoscopic Sinus Surgery|Heart Rate|Blood Loss
Interventions: DRUG: Verapamil|DRUG: Bisoprolol|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methylnaltrexone Use for Opioid-induced Postoperative Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Methylnaltrexone|DRUG: Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SDX-3101 for the Treatment of Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)
Status: WITHDRAWN
Conditions: Chronic Rhinosinusitis Without Nasal Polyps
Interventions: DEVICE: Vibration Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Copper T380 IUD Versus Oral Levonorgestrel for Emergency Contraception vs. Plan B for Emergency Contraception
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Copper T380 IUD|DRUG: levonorgestrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: OTHER: Group I: L. plantarum UALp-05TM,|OTHER: Group II: L. plantarum UALp-05TM,|OTHER: Microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Single-site, Open-label, Randomized, Cross-over Study in Healthy Chinese Subjects to Evaluate the Bioequivalence of Single-dose Rotigotine Transdermal Patch Comparing 2 Different Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rotigotine PR2.2.1|DRUG: Rotigotine PR2.1.1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Human MUC-1 (Mucin-1) Adenoviral Vector Vaccine for Immunotherapy of Epithelial Cancers
Status: UNKNOWN
Conditions: Epithelial Cancers of the Lung, Breast, Ovary, Prostate and Colon
Interventions: DRUG: Ad-sig-hMUC-1/ecdCD40L vector vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Identity-Based Transdiagnostic Therapy (IBTT)|BEHAVIORAL: Unified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation and Characterization of Signal Decrease on an Oximeter in COPD (They Have Chronic Obstructive Pulmonary Disease) Patients During Deep Inhalation (
Status: COMPLETED
Conditions: Pulmonary Disease|Copd
Interventions: OTHER: Measurements of oxygen saturation and finger pressure during deep inspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High Tidal Volume Induces Inflammation In Normal Lungs
Status: COMPLETED
Conditions: Mechanically Ventilated Patients|Normal Lungs
Interventions: PROCEDURE: Low tidal volume|PROCEDURE: Low tidal volume|OTHER: low tidal volume
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Evolution of Olfactory Disorders in Patients With Persistent Loss of Smell Following COVID-19
Status: RECRUITING
Conditions: SARS-CoV-2 Acute Respiratory Disease
Interventions: OTHER: Clinical examination|OTHER: Blood collection|OTHER: Olfactory evoked potentials|OTHER: Brushing of olfactory slits|OTHER: Neurological examination and neuropsychological assessment|OTHER: Nasal endoscopy|OTHER: Assessment of olfactory and taste functions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: ENDS (ENDometriosis & FuSobacterium) Unveiling the Contribution of Fusobacterium Infection to the Development of Endometriosis
Status: NOT_YET_RECRUITING
Conditions: Endometriosis
Interventions: DIAGNOSTIC_TEST: Fusobacterium detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaginal Dinoprostone Versus Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy
Status: UNKNOWN
Conditions: Postmenopausal Bleeding
Interventions: DRUG: INH|DRUG: dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer
Status: COMPLETED
Conditions: Metastatic Non-Small Cell Lung Carcinoma|Metastatic Colorectal Cancer|Metastatic Breast Cancer
Interventions: DIAGNOSTIC_TEST: Blood-based cell-free cfDNA qPCR assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Treatment of Obstructive Sleep Apnea Syndrome by Continuous Positive Airway Pressure Equipment at Night on the Lower Urinary Tract Symptoms and the Erectile Dysfunction
Status: UNKNOWN
Conditions: Lower Urinary Tract Symptoms|Erectile Dysfunction|Obstructive Sleep Apneas Syndrom
Interventions: OTHER: questionnaire passation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study With Aminophylline to Attenuate of the Side Effects of Regadenoson
Status: TERMINATED
Conditions: Patients Being Assessed With Nuclear Stress Testing of the Heart Using the Stress Agent Regadenoson, Lexiscan
Interventions: DRUG: Aminophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sub-Occipital Muscles Inhibition Technique Verses Cranio Cervical Flexion Exercise for Mechanical Neck Pain
Status: COMPLETED
Conditions: Cervical Pain|Mechanical Neck Pain
Interventions: OTHER: Suboccipital Inhibition Technique|OTHER: Cranio Cervical Flexion Exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention to Improve Kidney Transplant Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Transplant; Complications|Kidney Diseases|Transplant;Failure,Kidney|Diabetes|Hypertension|Obesity|Diet, Healthy|Lifestyle, Healthy
Interventions: BEHAVIORAL: Dietary Education Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial to Evaluate the Efficacy of Topical Bexarotene Gel in Patients With Parapsoriasis
Status: TERMINATED
Conditions: Parapsoriasis
Interventions: DRUG: Bexarotene 1% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: CAD106|BIOLOGICAL: Placebo|BIOLOGICAL: Alum|BIOLOGICAL: MF59
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Closed-loop Ventilation to Reduced Sleep Disorders
Status: COMPLETED
Conditions: Acute Mechanical Ventilatory Failure|Psychosis Associated With Intensive Care
Interventions: DEVICE: Intellivent-ASV|DEVICE: Conventional ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Hydrocortisone and Placebo in Patients With Symptoms of Adrenal Insufficiency After Cessation of Glucocorticoid Treatment
Status: RECRUITING
Conditions: Adrenal Insufficiency
Interventions: DRUG: Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ALLO-715 BCMA Allogenic CAR T Cells in in Adults With Relapsed or Refractory Multiple Myeloma (UNIVERSAL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: GENETIC: ALLO-715|BIOLOGICAL: ALLO-647|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Nirogacestat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Treatment of Migraines Using the Avulux™ Optical Filter in the Form of Spectacle Lenses.
Status: COMPLETED
Conditions: Migraine
Interventions: OTHER: HIT-6 Questionnaire|DEVICE: Avulux Spectacles|DEVICE: Sham Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant
Status: NOT_YET_RECRUITING
Conditions: Acute Leukemia|Acute Leukemia of Ambiguous Lineage|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Childhood Acute Leukemia|Childhood Acute Leukemia of Ambiguous Lineage|Childhood Acute Lymphoblastic Leukemia|Childhood Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Echocardiography|OTHER: Electronic Health Record Review|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Revumenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Potential Efficacy of AVT001 in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: AVT001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exclusive Enteral Nutrition and Corticosteroids Therapy in Crohn's Disease (EENCD)
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Prednisone|DIETARY_SUPPLEMENT: Exclusive Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAOIB Combined With tDCS for Early-phase Dementia
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Dementia
Interventions: DRUG: DAOIB|DRUG: Placebo|DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of an Ophthalmic Solution to Reduce Intraocular Pressure in Patients With Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: C-KAD Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of BBB Disruption Using NaviFUS System in Recurrent Glioblastoma Multiforme (GBM) Patients
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Brain Tumor|Glioblastoma|Glioma|Neoplasms|Neoplasms, Nerve Tissue
Interventions: DEVICE: NaviFUS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: 68Ga-AAZTA-093 PET/CT: First-in-human Study
Status: RECRUITING
Conditions: Malignant Neoplasm of Prostate
Interventions: DRUG: 68Ga-AAZTA-093|DRUG: 68Ga-PSMA-11//68Ga-PSMA-617
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Drug Interaction Study of Boceprevir in Combination With Amlodipine or Diltiazem in Healthy Volunteers
Status: WITHDRAWN
Conditions: Hepatitis C|Hypertension
Interventions: DRUG: Amlodipine|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia
Status: UNKNOWN
Conditions: Sciatica
Interventions: DRUG: Paracetamol|DRUG: morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SU5416 Combined With Gemcitabine and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: cisplatin|DRUG: gemcitabine hydrochloride|DRUG: semaxanib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Pain Relief During Perineal Repair After Childbirth
Status: COMPLETED
Conditions: Birth Injuries|Lacerations|Pain
Interventions: PROCEDURE: acupuncture in 6 specific points|DRUG: lidocaine 10mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of ICG@HSA Complexes in Fluorescence Image-Guided Laparoscopic Anatomical Liver Resection
Status: RECRUITING
Conditions: Malignant Tumor of Liver|Randomized Controlled Trial
Interventions: PROCEDURE: NIF image-guided laparoscopic anatomical liver resection with the novel ICG@HSA administration|PROCEDURE: NIF image-guided laparoscopic anatomical liver resection with the guideline-recommended ICG administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety Study of Filgrastine® in Patientes With Breast Cancer Treated With Myelotoxic Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: Granulokine|BIOLOGICAL: Filgrastine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Status: RECRUITING
Conditions: Ankylosing Spondylitis|Autoimmune Disease|Crohn Disease|Enteropathic Arthritis|Enteropathic Spondylitis|Inflammatory Bowel Disease|Melanoma|Psoriasis|Psoriatic Arthritis|Reactive Arthritis|Rheumatoid Arthritis|Systemic Lupus Erythematosus|Ulcerative Colitis
Interventions: OTHER: Best Practice|OTHER: Educational Intervention|OTHER: Interview|OTHER: Questionnaire Administration|OTHER: Survey Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia
Status: UNKNOWN
Conditions: Anesthesia, Obstetrical
Interventions: DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized, Blinded, Placebo-controlled Phase I Clinical Trial Evaluating the Safety and Preliminary Immunogenicity of a 11-valent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha) in Chinese Women Aged 9-45 Years
Status: COMPLETED
Conditions: HPV Infection|HPV-Related Cervical Carcinoma
Interventions: BIOLOGICAL: 11-valent recombinant human papilloma virus vaccine (Hansenula polymorpha)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Paxalisib (GDC-0084) In Recurrent Or Refractory PCNSL
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma|Non-Hodgkin Lymphoma of Extranodal Site
Interventions: DRUG: PAXALISIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy and Medically Assisted Conception in Rare Diseases
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Spondyloarthritis|Psoriatic Arthritis|Systemic Lupus Erythematosus|Antiphospholipid Syndrome|Sjogren Syndrome|Scleroderma|Myositis|Vasculitis|Mastocytosis|Various Autoimmune and/or Systemic and/or Rare Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of The Effects of Different Stretching Techniques in Overhead Athletes
Status: NOT_YET_RECRUITING
Conditions: Glenohumeral Internal Rotation Deficit
Interventions: OTHER: Post Isometric Relaxation Group|OTHER: Isolytic Stretching Group|OTHER: Static Stretching Group Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flexible URS in Management of Renal Stones in Anomalous Kidney
Status: UNKNOWN
Conditions: Endourology|Stones, Kidney|Laser|Congenital Disorders|Horseshoe Kidney|Malrotation of Kidney|Ectopic Kidney
Interventions: PROCEDURE: flexible ureterorenoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke
Status: RECRUITING
Conditions: Acute Cerebrovascular Accident
Interventions: PROCEDURE: Individualized blood pressure|PROCEDURE: Standard blood pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: A Study to Compare the Effectiveness of a Four Drug Anti-HIV Regimen Given Alone or in Combination With GM-CSF or IL-12 to HIV-Positive Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine/Zidovudine|BIOLOGICAL: Hepatitis A Vaccine (Inactivated)|DRUG: Interleukin-12|DRUG: Nevirapine|DRUG: Stavudine|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Participation in a Pre-Operative Physical Activity Program Improve Patient Outcomes and Quality of Life?
Status: UNKNOWN
Conditions: Obesity|Bariatric Surgery|Roux-En-Y Gastric Bypass|Exercise|Quality of Life
Interventions: BEHAVIORAL: ENCOURAGEING START
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Combined Praziquantel and Albendazole vs Albendazole Alone to Treat Active Parenchymal Neurocysticercosis
Status: NOT_YET_RECRUITING
Conditions: Neurocysticercosis
Interventions: DRUG: albendazole and praziquantel|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Response to Lower Body Negative Pressure in Pre-hypertensive States
Status: COMPLETED
Conditions: Hypertension|Obesity|White Coat Hypertension|Resistant Hypertension
Interventions: OTHER: Lower body negative pressure (LBNP)|DRUG: Candesartan cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Open-label, Dose-escalation Safety and Tolerability Trial Assessing Anti-KIR (1-7F9) in Subjects With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Anti-KIR (1-7F9)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Of Sildenafil Orally Disintegrating Tablet Formulation Given With Or Without Food.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Sildenafil|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Manual Muscle Relaxation Techniques in the Treatment of Temporomandibular Joint Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorder|Temporomandibular Joint Disorders
Interventions: PROCEDURE: Post-isometric muscle relaxation technique|PROCEDURE: Myofascial release technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Stage IV Prostate Cancer|Advanced Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: Adaptive Androgen Deprivation Therapy (ADT)|DRUG: Abiraterone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Acute Kidney Injury After Operation of Acute Type A Aortic Dissection Based on Multimodal Model
Status: UNKNOWN
Conditions: Aneurysm, Dissecting|Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Normal CT Renal Perfusion imaging indexes|DIAGNOSTIC_TEST: Low CT Renal Perfusion imaging indexes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Abdominal Wall Nerve Blockade: A Comparison With Local Port Site Injection as Well as Between the Use of Ultrasound and Laparoscopy to Guide Placement
Status: WITHDRAWN
Conditions: Postoperative Pain
Interventions: PROCEDURE: laparoscopic guided nerve blocks|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparative Study of Rimazolam and Propofol Combined With Etomidate in Gastroenteroscopy in Elderly Patients
Status: COMPLETED
Conditions: Elderly Patients|Gastrointestinal Endoscopy|Remimazolam Besylate|Etomidate Combined With Propofol
Interventions: DRUG: Remimazolam Besylate|DRUG: etomidate combined with propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide|DRUG: paclitaxel|DRUG: topotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Injection of Bevacizumab and Gas for Diabetic Premacular Hemorrhage With Active Fibrovascular Proliferation
Status: UNKNOWN
Conditions: Diabetic Retinopathy With Premacular Hemorrhage
Interventions: DRUG: Intravitreal Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
Status: RECRUITING
Conditions: PANDAS|Anxiety Disorder|Autoimmune Diseases|Obsessive-Compulsive Disorder
Interventions: DRUG: Naproxen Sodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Recurrent or Extensive-Stage Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer Extensive Stage
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy of AI-Guided (GenAIS TM) vs. Standard Physician-Guided Dietary Supplement Prescriptions for Weight Loss in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Control Group|OTHER: AI-Guided Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Parental Support in Families Using the LENA After Early Cochlear Implantation
Status: NOT_YET_RECRUITING
Conditions: Profound Congenital Deafness|Cochlear Implantation
Interventions: OTHER: LENA tool: Language ENvironment Analysis|BEHAVIORAL: Return of the analysis of the data of LENA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cook IVC Filter Study
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DEVICE: Günther Tulip® Vena Cava Filter|DEVICE: Cook Celect® Vena Cava Filters
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Investigation to Evaluate Microwave Imaging Via MammoWave® in a Population-based Screening Program for Early Breast Cancer Detection
Status: RECRUITING
Conditions: Women's Health: Neoplasm of Breast
Interventions: DEVICE: MammoWave
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: Codeine + Diclofenac|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thulium Fiber Laser Enucleation of the Prostate (TFLEP) vs HoLEP With Moses Technology (m-HoLEP)
Status: RECRUITING
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: TFLEP|PROCEDURE: m-HoLEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Effects on tPCS and tDCS on Healthy Subjects and on Patients With Chronic Visceral Pain
Status: COMPLETED
Conditions: Visceral Pain|Pancreatitis|Pelvic Pain
Interventions: DEVICE: Active tPCS|DEVICE: Active tDCS|DEVICE: Sham tPCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors
Status: COMPLETED
Conditions: Bone Marrow Suppression|Brain and Central Nervous System Tumors|Drug/Agent Toxicity by Tissue/Organ
Interventions: PROCEDURE: filgrastim|BIOLOGICAL: gene therapy|DRUG: lomustine|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults
Status: NOT_YET_RECRUITING
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis|Hepatitis B|Haemophilus Influenzae Type b Infection
Interventions: BIOLOGICAL: DTaP-HepB-IPV-Hib vaccine|BIOLOGICAL: DTaP-HepB-IPV-Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Evaluation of Fecal Immunologic Test (FIT) in Ontario
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: mailing of FIT kit directly to patient|OTHER: mailed invitation to pick up lab requisition and then kit|OTHER: mailing completed kits in for processing|OTHER: dropping completed kits at lab for processing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing a WeChat-based Integrative Family Intervention (WIFI) for Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: BEHAVIORAL: WeChat-based integrative family intervention (WIFI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)
Status: RECRUITING
Conditions: Pain|Appetite Loss|Abuse, Drug
Interventions: DRUG: Placebo|DRUG: Low CBG|DRUG: High CBG|DRUG: Low THC|DRUG: High THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
Status: COMPLETED
Conditions: Impacted Wisdom Tooth|Pain|Staphylococcus Aureus
Interventions: DIAGNOSTIC_TEST: Diagnosis|DRUG: Analgesic|PROCEDURE: traditional osteotomies|BIOLOGICAL: Platelet Rich Fibrin|DRUG: Antibiotic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TEAMS R34 #3: Team Communication Training for Pediatric Depression Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Children
Interventions: BEHAVIORAL: Team Communication Training|BEHAVIORAL: Early Identification Universal Depression Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Folic Acid Clinical Trial for the Prevention of Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: DIETARY_SUPPLEMENT: folic acid|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
Status: RECRUITING
Conditions: Metastatic Urothelial Cancer
Interventions: DRUG: BT8009|DRUG: BT8009|DRUG: BT8009|DRUG: Pembrolizumab|DRUG: Gemcitabine + cisplatin Or carboplatin|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Characteristics of People With Long-term Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BIOLOGICAL: Chronic hyperglycemia|BIOLOGICAL: Residual islet function|GENETIC: Genetic variation|DIETARY_SUPPLEMENT: Dietary constitutes|GENETIC: Microbiome composition and function|BIOLOGICAL: Metabolome composition|BIOLOGICAL: Composition of peripheral blood immune cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chlorhexidine Gluconate for Prevention of Ventilator Associated Pneumonia in Children.
Status: UNKNOWN
Conditions: Mechanical Ventilation for More Than 48 Hours.
Interventions: DRUG: 0.12% chlorhexidine solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Videolaryngoscopes for Double Lumen Tube Intubations in Simulated Easy and Difficult Airway
Status: COMPLETED
Conditions: Staff Anaesthesiologists|Limited Experience in Using Videolaryngoscopes
Interventions: DEVICE: Macintosh|DEVICE: GlideScope|DEVICE: Airtraq|DEVICE: King Vision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Harnessing mHealth and Social Support to Improve Diabetes Related Health Behavior for Inner-city Patients
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: TExT MED|BEHAVIORAL: FANS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Perception of Temporal Regularity in Tactile Stimulation: a Diffuse Correlation Spectroscopy Study in Preterm Neonates
Status: UNKNOWN
Conditions: Premature Birth
Interventions: BEHAVIORAL: Regular stimulation sequence|BEHAVIORAL: Random stimulation sequence|DEVICE: DCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Egg Protein Hydrolysate and Vascular Function
Status: COMPLETED
Conditions: Arterial Stiffness|Dietary Modification|Impaired Glucose Tolerance|Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: protein hydrolysate capsules and placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Exercise Training on Living Quality in Multiple Sclerosis Individuals
Status: COMPLETED
Conditions: Multiple Sclerosis|Fatigue|Mental Status Change|Physical Disability|Physical Activity|Mental Impairment|Quality of Life|Disabilities Psychological|Disability Physical|Pain|Energy Supply; Deficiency|Motivation
Interventions: BEHAVIORAL: Exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Immunogenicity of the GSK Bio CMV Vaccine in CMV-seronegative Healthy Male Adult Subjects
Status: COMPLETED
Conditions: Infections, Cytomegalovirus
Interventions: BIOLOGICAL: GSK Biologicals' Recombinant CMV gB Vaccine GSK1492903A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HDR Brachytherapy Plus Stereotactic Ablative Prostate Radiotherapy for Patients With Intermediate and High-risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostatic Neoplasm
Interventions: RADIATION: Real time High-Dose-Rate prostate brachytherapy in combination with stereotactic prostate radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of BIVV009 (Sutimlimab) in Participants With Primary Cold Agglutinin Disease Who Have a Recent History of Blood Transfusion (Cardinal Study)
Status: COMPLETED
Conditions: Agglutinin Disease, Cold
Interventions: DRUG: BIVV009
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trigeminal Evoked Responses to Improve Rhizotomy
Status: RECRUITING
Conditions: Trigeminal Neuralgia|Rhizotomy
Interventions: OTHER: TSEP + rhizotomy surgery|OTHER: TSEPs recording only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomised Controlled Treatment Study of Selective Mutism
Status: COMPLETED
Conditions: Selective Mutism
Interventions: BEHAVIORAL: Stimulus fading procedures|BEHAVIORAL: Guidance on defocused communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms
Status: COMPLETED
Conditions: Chronic Postoperative Pain
Interventions: PROCEDURE: Inguinal herniorraphy.|PROCEDURE: Hysterectomy.|PROCEDURE: Thoracotomy .
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-finding Study of WS6788A, DS37-4 and H10407 Enterotoxigenic Escherichia Coli (ETEC) Challenge Strains
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: H10407
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Behavioural Study in Chronic Pain : Creativity and Motivation, and Circuits Involved in Functional MRI
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: art-therapy|BEHAVIORAL: relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Monoarticular Corticosteroid Injection Versus Systemic Administration in the Treatment of Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: intraarticular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
Status: UNKNOWN
Conditions: Sugammadex
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients
Status: TERMINATED
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: CP-945,598|DRUG: CP-945,598 Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Trial to Evaluate Efficacy of Alpha-Lipoic Acid in Treating Symptomatic Diabetic Polyneuropathy in Egypt
Status: RECRUITING
Conditions: Polyneuropathy, Diabetic
Interventions: DRUG: Alpha-Lipoic Acid (ALA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibromyalgia Integrative Training for Teens
Status: COMPLETED
Conditions: Juvenile Fibromyalgia
Interventions: BEHAVIORAL: Fibromyalgia integrative training|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota Transfer Therapy for Children and Adults With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders
Status: RECRUITING
Conditions: Pitt Hopkins Syndrome
Interventions: COMBINATION_PRODUCT: MTP-101P|COMBINATION_PRODUCT: Vancomycin|COMBINATION_PRODUCT: Magnesium Citrate|COMBINATION_PRODUCT: Antacid|COMBINATION_PRODUCT: Placebo MTP-101P|COMBINATION_PRODUCT: Placebo Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Support for Post Intensive Care Syndrome Self-Management
Status: UNKNOWN
Conditions: Critical Illness|Sepsis|Shock, Septic|Shock|Respiratory Failure|Respiratory Distress Syndrome, Adult|Shock, Hypovolemic|Chronic Disease
Interventions: BEHAVIORAL: Peer Support with Motivational Interviewing|BEHAVIORAL: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: IN10018|DRUG: Albumin-Bound Paclitaxel|DRUG: Gemcitabine|DRUG: KN046
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canadian Adult Congenital Heart Disease Intervention Registry
Status: NOT_YET_RECRUITING
Conditions: Atrial Septal Defect|Patent Foramen Ovale|Tetralogy of Fallot|Fontan|Coarctation of Aorta|Transposition of Great Vessels|Percutaneous Pulmonary Valve Implantation
Interventions: OTHER: Participants undergoing ACHD intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Emotional Disorders in Primary Care With Psychological Techniques
Status: COMPLETED
Conditions: Anxiety Disorders|Mood Disorders|Somatization Disorder|Pain Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Treatment|DRUG: Primary Care Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT