pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CT-2103 in Combination With Gemcitabine in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer|Breast Cancer
Interventions: DRUG: CT-2103|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Asenapine [P06107 (NCT01244815)] for Pediatric Bipolar Disorder (P05898)
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Asenapine|DRUG: Rescue medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Combined Intravitreal bevacizumab and propranolol|DRUG: Intravitreal bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Healthy Japanese Infants (V114-033)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: V114|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans
Status: COMPLETED
Conditions: Bronchiolitis Obliterans|Constructive Bronchiolitis|Graft Versus Host Disease|Bronchiolitis, Exudative|Bronchiolitis, Proliferative|Graft-Versus-Host Disease
Interventions: DRUG: Cyclosporine Inhalation Solution (CIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain After Lung Cancer Surgery - Comparing Traditional Versus Prolonged Release Nerve Blockades
Status: UNKNOWN
Conditions: Postoperative Pain|Lung Cancer|Video Assisted Thoracoscopic Surgery|Blockades Neuromuscular|Anesthesia, Local
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DP303c Injection in Patients With Advanced or Metastatic Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: DP303c treatment|DRUG: DP303c treatment（second-line of HER2-positive）|DRUG: DP303c treatment （third-line of HER2-positive）|DRUG: DP303c treatment（≥second-line of HER2 low expressing）|DRUG: DP303c + PD-1/PD-L1 treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Skin Safety Testing of a Mitopure Topical Product Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volunteers
Status: COMPLETED
Conditions: Irritation/Irritant|Sensitisation
Interventions: OTHER: Mitopure Topical Formula 1|OTHER: Mitopure Topical Formula 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endo-cuff Assisted Vs. Standard Colonoscopy for Polyp Detection in Bowel Cancer Screening
Status: COMPLETED
Conditions: Colonic Polyps|Colonic Neoplasms
Interventions: DEVICE: Endo-cuff|OTHER: Standard colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers
Status: UNKNOWN
Conditions: Acute Kidney Injury|Renal Calculi|Percutaneous Nephrolithotomy|Extracorporeal Shockwave Lithotripsy
Interventions: PROCEDURE: Percutaneous nephrolithotomy|PROCEDURE: Extracorporeal Shock Wave Lithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Trial of Lonafarnib (a Farnesyltransferase Inhibitor) for Progeria
Status: COMPLETED
Conditions: Progeria|Hutchinson-Gilford Syndrome
Interventions: DRUG: Lonafarnib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity for Regimen Selection of Ad26.RSV.preF and/or RSV preF Protein Combinations Followed by Expanded Safety Evaluation in Adults Aged 60 Years and Older
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: RSV preF Protein 50 mcg|BIOLOGICAL: RSV preF Protein 150 mcg|BIOLOGICAL: Ad26.RSV.preF 1*10^11 vp|BIOLOGICAL: Mixture of Ad26.RSV.preF 5*10^10 vp Plus RSV preF Protein 50 mcg|BIOLOGICAL: Mixture of Ad26.RSV.preF 5*10^10 vp Plus RSV preF Protein 150 mcg|BIOLOGICAL: Mixture of Ad26.RSV.preF 1*10^11 vp Plus RSV preF Protein 50 mcg|BIOLOGICAL: Mixture of Ad26.RSV.preF 1*10^11 vp Plus RSV preF Protein 150 mcg|BIOLOGICAL: Selected Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Antioxidant and Preeclampsia Prediction Studies (CAPPS)
Status: COMPLETED
Conditions: Preeclampsia
Interventions: DRUG: Dietary Supplement/Vitamins|DRUG: Placebo for Vitamin C and Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: XCEL Bladeless Trocar Versus Veress Needle: A Randomised Controlled Trial Comparing These Two Entry Techniques in Gynaecological Laparoscopic Surgery.
Status: UNKNOWN
Conditions: Laparoscopic Surgery
Interventions: PROCEDURE: laparoscopic surgery|PROCEDURE: laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Oncoxin-Viusid® in Cervical Cancer and Endometrial Adenocarcinoma.
Status: COMPLETED
Conditions: Cervical Carcinoma Stage II|Cervical Carcinoma Stage III|Cervical Carcinoma Stage IV|Endometrial Adenocarcinoma Stage II|Endometrial Adenocarcinoma Stage III|Endometrial Adenocarcinoma Stage IV
Interventions: DIETARY_SUPPLEMENT: Oncoxin-Viusid®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Lerapolturev|BIOLOGICAL: Anti-PD-1 Checkpoint Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Characteristics and Predictors of Adverse Outcomes in HFpEF
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction
Interventions: COMBINATION_PRODUCT: The study involved a comparison of clinical characteristics, medical history, laboratory biomarkers, echocardiographic measurements, angiographic findings, and clinical outcomes between two groups.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implantable Microdevice In Primary Brain Tumors
Status: RECRUITING
Conditions: Grade II Glioma|Grade III Glioma|Grade IV Glioma|Astrocytoma|Oligodendroglioma of Brain|Anaplastic Astrocytoma of Brain|Anaplastic Oligodendroglioma|Glioblastoma
Interventions: COMBINATION_PRODUCT: Microdevice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504
Status: COMPLETED
Conditions: Retraction of Colostomy
Interventions: DRUG: IV morphine sulfate or Sponsor-approved equivalent|DRUG: EXPAREL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nebulized Sub-dissociative Dose Ketamine for Treating Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine 0.75 mg/kg|DRUG: Ketamine 1.0 mg/kg|DRUG: Ketamine 1.5 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of RIC on the Orthostatic Competence of the Microcirculation
Status: ACTIVE_NOT_RECRUITING
Conditions: Microcirculation|Orthostatic Intolerance|Remote Ischemic Preconditioning|Hemodynamics
Interventions: PROCEDURE: Remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets in Chinses Healthy Subjects
Status: UNKNOWN
Conditions: Insomnia
Interventions: DRUG: HEC83518 tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Pembrolizumab|DRUG: IO102-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Status: COMPLETED
Conditions: Maternal Distress|Perinatal Depression|Development Delay|Language Delay|Cognitive Developmental Delay|Nutrition Poor|Growth Delay|Motor Delay|Maternal Behavior|Infant Development|Infant Malnutrition|Infant Behavior
Interventions: BEHAVIORAL: Intervention arm|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma (Stage IIIC Non-résécable or no Surgically Curable or Stage IV With Classification AJCC)
Interventions: DRUG: Metformin Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of IV Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy
Status: UNKNOWN
Conditions: Arrhythmias, Cardiac|Atrial Fibrillation
Interventions: DRUG: Intravenous Sotalol Administered as a Loading Dose to Initiate Oral Sotalol Therapy in Adult Patients with Atrial Fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-label Randomized Controlled Trial Comparing the Role of Therapeutic Plasma-exchange in Ameliorating Secondary Organ Dysfunctions in Patients With ACLF and Develop Biomarkers of Treatment Response
Status: NOT_YET_RECRUITING
Conditions: Acute on Chronic Liver Failure
Interventions: BIOLOGICAL: Plasma Exchange|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dovitinib in BCG Refractory Urothelial Carcinoma With FGFR3 Mutations or Over-expression
Status: TERMINATED
Conditions: Bladder Cancer
Interventions: DRUG: Dovitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of the PfSPZ Vaccine Administered by Direct Venous Inoculation in Healthy Malaria-Naïve Adults: Heterologous vs. Homologous Controlled Human Malaria Infection and Reduction in Number of Doses
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: In-Situ Simulation Different Debriefing Methods
Status: COMPLETED
Conditions: Nursing Caries|Satisfaction|Simulation of Physical Illness
Interventions: BEHAVIORAL: LC-Based Debriefing|BEHAVIORAL: 3D Model-Based Debriefing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Testosterone in Men With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction|Testosterone Deficiency|Diabetes
Interventions: DRUG: Sildenafil citrate (open label)|DRUG: Testosterone gel|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioresorbable Polymer-Coated EES in Patients at High Bleeding Risk Undergoing PCI Followed by 1-Month DAPT
Status: UNKNOWN
Conditions: Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DRUG: Aspirin|DRUG: P2Y12 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pimecrolimus for the Treatment of Vitiligo Vulgaris
Status: COMPLETED
Conditions: Vitiligo Vulgaris
Interventions: DRUG: Application of pimecrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects on Blood Pressure Control, Pulse Wave Velocity, as Well as Safety and Tolerability of Felodipine Sustained Release in Chinese Patients.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Felodipine tablet (Plendil) alone|DRUG: Felodipine tablet (Plendil)+Hydrochlorothiazide|DRUG: Felodipine tablet (Plendil)+Metoprolol tablet (Betaloc ZOK)|DRUG: Felodipine tablets (Plendil)+Lisinopril (Zestril)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion
Status: NOT_YET_RECRUITING
Conditions: Moyamoya Syndrome|Moyamoya Disease|Atheroscleroses, Cerebral
Interventions: DEVICE: Soterix® 4x1HD-TDCS|DEVICE: Soterix® 1x1 tDCS|BEHAVIORAL: Cognitive training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Algeness DF 3.5% Compared to Voluma in Volume Deficit in Mid-face
Status: UNKNOWN
Conditions: Age-Related Volume Deficit in the Mid-Face
Interventions: DEVICE: Algeness® DF 3.5%|DEVICE: Juvéderm Voluma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C11-Erlotinib PET/CT as a Tool for Identification and Characterization of Tumor With High Expression of Epidermal Growth Factor Receptor(EGFR).
Status: UNKNOWN
Conditions: Lung Cancer|Pancreatic Cancer
Interventions: OTHER: C11-Erlotinib PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Weight Loss on Nutritional Mediated Hormone Secretion
Status: COMPLETED
Conditions: Weight Loss|Hormone Disturbance|Weight Gain
Interventions: DIETARY_SUPPLEMENT: nutritional stimulation via different testmeals|OTHER: Nutritional counseling|DIETARY_SUPPLEMENT: formula diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter
Status: RECRUITING
Conditions: Nephrolithotomy, Percutaneous|Kidney Calculi
Interventions: PROCEDURE: without reverse ureteral catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BIOLOGICAL: Autologous stem cells|OTHER: Hyperbaric oxygen therapy|DRUG: Insulin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Guided Mobile App Intervention for Depression and Anxiety in University Students (PROMES-U Study)
Status: NOT_YET_RECRUITING
Conditions: Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: MyMoodCoach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactose, Sucrose & Corn Syrup Tolerance
Status: COMPLETED
Conditions: Focus of Study: Oral Tolerance Test With Glucose, Lactose, Sucrose
Interventions: DIETARY_SUPPLEMENT: corn syrup solids|DIETARY_SUPPLEMENT: sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-54767414 (Daratumumab) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Daratumumab|DRUG: Placebo|DRUG: rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD
Status: RECRUITING
Conditions: Obstructive Sleep Apnea|OSA COPD Overlap Syndrome
Interventions: DEVICE: Positive airway pressure|DEVICE: NIPPV and /or oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare ORMD-0801 Once Daily to ORMD-0801 Three Times Daily in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: ORMD-0801 Treatment A|DRUG: ORMD-0801 Treatment B|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective Effect of Remote Ischemic Post-conditioning in Out-of-hospital Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: OTHER: Remote ischemic post conditioning sessions|OTHER: Sham sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
Status: COMPLETED
Conditions: Central Venous Catheterization|Ultrasound|Emergency Medicine|Critical Care
Interventions: PROCEDURE: Point of care echocardiography|DEVICE: Central venous catheter placement|PROCEDURE: Chest radiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relative Bioavailability of Dabigatran and Diclofenac After Dabigatran Etexilate and Diclofenac Single Dose Alone or Following Concomitant Multiple Oral Administrations in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dabigatran etexilate|DRUG: Diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bezlotoxumab (MK-6072) Versus Placebo in Children With Clostridium Difficile Infection (CDI) (MK-6072-001)
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: BIOLOGICAL: Bezlotoxumab|DRUG: Placebo|DRUG: Antibacterial drug treatment (ABD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy and Safety of Traditional Chinese Medicine (TCM) to the Patient With Dizziness in Emergency Department
Status: WITHDRAWN
Conditions: Dizziness
Interventions: OTHER: Acupuncture|OTHER: Far-Infrared heat-patch attachment|OTHER: Acupuncture and Fir-Infrared heat-patch attachment|OTHER: Far-Infrared heat-patch attachment over acupoints without electric current passing.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage II Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: defined green tea catechin extract|DRUG: placebo|OTHER: immunohistochemistry staining method|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy|OTHER: mass spectrometry|OTHER: high performance liquid chromatography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Novel Fiber on Glucose Homeostasis in Individuals at Risk for Diabetes
Status: TERMINATED
Conditions: Insulin Resistance
Interventions: OTHER: Novel dietary fiber|OTHER: Novel dietary fiber|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Comparing Valsartan With And Without Hydrochlorothiazide In Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: VALSARTAN, VALSARTAN+HYDROCHLOROTHIAZIDE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Block Versus Thoracic Paravertebral Block for Postoperative Pain Control After Open Nephrectomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: erector spinae block|PROCEDURE: thoracic paravertebral block|DRUG: Pethidine Only Product in Parenteral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ibrutinib Plus Rituximab and Lenalidomide in Treating Elderly Participants With Newly Diagnosed Mantle Cell Lymphoma
Status: WITHDRAWN
Conditions: CCND1 Positive|CD20-Positive Neoplastic Cells Present|Mantle Cell Lymphoma
Interventions: DRUG: Dexamethasone|DRUG: Ibrutinib|DRUG: Lenalidomide|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Acute|Hypertriglyceridemia
Interventions: DRUG: Insulin|DEVICE: Aphesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Patient Reported Outcomes in Renal Transplant Patients With and Without Gastrointestinal (GI) Symptoms (PROGIS)
Status: COMPLETED
Conditions: Kidney Maintenance Transplant
Interventions: DRUG: Enteric-coated Mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy to Prevent Osteopenia in Preterm Infants
Status: COMPLETED
Conditions: Metabolic Bone Disease
Interventions: PROCEDURE: Reflex Locomotion Therapy|PROCEDURE: Passive Joint Mobilizations|PROCEDURE: Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study to Evaluate the Tolerability and Pharmacokinetics of TQB3617 Capsule in Patients With Advanced Malignant Tumors
Status: UNKNOWN
Conditions: Advanced Malignant Tumors
Interventions: DRUG: TQB3617
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monthly Replacement Orthokeratology for Myopia Control in Existing Lens Wearers
Status: UNKNOWN
Conditions: Myopic Progression
Interventions: DEVICE: orthokeratology|DEVICE: Menicon Progent A+B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurosteroids in PTSD - Biomarkers to Therapeutics
Status: TERMINATED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: DHEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Needling on Spinal Mobility and Trigger Points in Patients With Fibromyalgia Syndrome.
Status: COMPLETED
Conditions: Fibromyalgia|Back Pain
Interventions: DEVICE: Dry Needling|OTHER: Cross Tape Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Chlorhexidine, Metronidazole and Combination Gels on Gingivitis
Status: UNKNOWN
Conditions: Gingivitis
Interventions: DRUG: Metronidazole gel|DRUG: Chlorhexidine Gluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nexus Compliance Study
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: CPAP Pre Nexus (S9)|DEVICE: Nexus (S9)|DEVICE: CPAP Post Nexus (S9)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Elderberry Juice on Cognition and Inflammation in Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BIOLOGICAL: Elderberry Juice|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effects of Folic Acid Supplementation in Older Adults: The Folic Acid Supplementation Trial (The FAST Study)
Status: COMPLETED
Conditions: Heart Diseases
Interventions: DIETARY_SUPPLEMENT: Folic Acid|DRUG: Placebo Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Collagen Peptide Supplementation on Muscle and Tendon Damage and Function
Status: COMPLETED
Conditions: Exercise|Healthy Male Subjects
Interventions: DIETARY_SUPPLEMENT: whey protein|DIETARY_SUPPLEMENT: whey protein + collagen peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Femoral Nerve Block for Femur Fracture Repair in Pediatrics
Status: TERMINATED
Conditions: Traumatic Femur Fracture
Interventions: DRUG: Ropivicaine|DRUG: Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rilonacept for Treatment of Familial Mediterranean Fever (FMF)
Status: COMPLETED
Conditions: Familial Mediterranean Fever
Interventions: DRUG: Rilonacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Methods Decreasing Bleeding in Open Myomectomy
Status: RECRUITING
Conditions: Misoprostol Allergy|Oxytocin Allergy|Tranexamic Acid Allergy|Ethamsylate Allergy|Myoma|Blood Loss, Surgical
Interventions: DRUG: Misoprostol|DEVICE: Tourniquet|DRUG: Carbetocin|DRUG: Oxytocin|DRUG: combined TXA and ethamsylate|DRUG: Vasopressin|DRUG: Bupivacaine Hydrochloride 0.5 % Injectable Solution epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Allogeneic Regulatory Dendritic Cell (DCreg) Renal Study
Status: RECRUITING
Conditions: Kidney Transplant|Renal Transplant Recipients
Interventions: BIOLOGICAL: DCreg: 0.5 million cells/kg+SOC|BIOLOGICAL: DCreg: 1.2 million cells/kg+SOC|BIOLOGICAL: DCreg:2.5 to 5.0 million cells/kg+SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Safety Study of CPP-109 (Vigabatrin) for Treatment Refractory Tourette's Disorder
Status: COMPLETED
Conditions: Tourette's Disorder
Interventions: DRUG: vigabatrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Low-Nicotine Cigarettes in Smokers With SUD
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Nicotine|BEHAVIORAL: behavioral counseling for smoking cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Abrocitinib in Subjects With Atopic Dermatitis With an Unsatisfactory Response After Treatment With Dupilumab
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Abrocitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening Magnetic Resonance Imaging of the Brain in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer|Triple Negative Breast Cancer|Hormone Receptor Positive Malignant Neoplasm of Breast|Inflammatory Breast Cancer|Metastatic Breast Cancer
Interventions: DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: 3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Surgery
Interventions: PROCEDURE: Indocyanine Green Tracer Using in 3D plus Ultra High Resolution Laparoscopic Gastrectomy with Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female Pelvic Floor Reconstructive Surgery
Status: COMPLETED
Conditions: Urinary Incontinence|Pelvic Organ Prolapse
Interventions: PROCEDURE: Retrograde bladder fill|OTHER: spontaneous void
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Bronchodilation Effects of Cetirizine
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma
Interventions: DRUG: Cetirizine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Exercise Programs Following Total Hip and Knee Joint Arthroplasty
Status: COMPLETED
Conditions: Hip and Knee Joint Osteoarthritis|Hip and Knee Joint Arthroplasty
Interventions: OTHER: Typical range of motion and muscle strengthening exercises, and balance exercises|OTHER: Typical group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARcopenia in Patients With ChrOnic PANcreatitis: the SARCOPAN Study
Status: RECRUITING
Conditions: Pancreatitis
Interventions: DIAGNOSTIC_TEST: Bioelectrical impedance|DIAGNOSTIC_TEST: Handgrip strength test|DIAGNOSTIC_TEST: muscle ultrasound.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The SENSOR Study: A Mixed-methods Study of SElf-management Checks to Predict exacerbatioNs of Pseudomonas Aeruginosa in Patients With Long-term reSpiratORy Conditions
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Asthma|Bronchiectasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Levothyroxine Sodium Tablets 100 mcg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Drug Levothyroxine 100 mcg|DRUG: Drug Eutirox 100 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of Treatment With LinearFirm(ULTRAcel Q+) in Temporary Eyebrow Lifting
Status: COMPLETED
Conditions: High Intensity Focused Ultrasound
Interventions: DEVICE: LinearZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Synbiotics and Gastrointestinal Function Related Quality of Life After Colectomy for Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Synbiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment Trial of Thermoregulatory Disturbances in Adolescent Anorexia Nervosa Patients With Either Ginger Powder Footbaths or Warm Water Footbaths
Status: COMPLETED
Conditions: Adolescent Anorexia Nervosa
Interventions: OTHER: ginger powder footbath|OTHER: warm water only footbath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank
Status: NOT_YET_RECRUITING
Conditions: Dry Eye Syndrome|Sjogren's Syndrome|Healthy Control|Inflammation
Interventions: DIAGNOSTIC_TEST: Whole-genome genotyping|DIAGNOSTIC_TEST: Whole-genome sequencing|DIAGNOSTIC_TEST: TCM pattern|DIAGNOSTIC_TEST: DNA Exome sequencing|DIAGNOSTIC_TEST: Physical examination indicators, blood, urine and biochemical function test|DIAGNOSTIC_TEST: Demographics, personal health behavior, living environment, dietary status, family history|DIAGNOSTIC_TEST: HLA typing|DIAGNOSTIC_TEST: Full-length 16S Amplicon Sequencing|DIAGNOSTIC_TEST: Epigenomic|DIAGNOSTIC_TEST: Metabolomics|DIAGNOSTIC_TEST: Environmental Toxic|DIAGNOSTIC_TEST: Medical Image
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]|DEVICE: AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
Status: COMPLETED
Conditions: Low Gelsolin|Trauma|Infection|Burns
Interventions: DRUG: rhu-pGelsolin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, PK/PD (Pharmacokinetics/Pharmacodynamics) and Efficacy of ACP-001 Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)
Status: COMPLETED
Conditions: Growth Hormone Deficiency (GHD)
Interventions: DRUG: ACP-001|DRUG: Human Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Extraperitoneal ( Modified) Burch Colposuspension
Status: RECRUITING
Conditions: Stress Incontinence, Female
Interventions: PROCEDURE: Quality of Life QUESTIONNAIRE (SF36)|PROCEDURE: INCONTINENCE IMPACT QUESTIONNAIRE (IIQ-7)|PROCEDURE: UROGENITAL DISTRESS INVENTORY (UDI - 6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Study of MT-2412 in Japanese Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin/Canagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saracatinib in Treating Patients With Metastatic or Locally Advanced Breast Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Estrogen Receptor-negative Breast Cancer|Male Breast Cancer|Progesterone Receptor-negative Breast Cancer|Recurrent Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: saracatinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Assessing Temelimab Following Rituximab Treatment in Patients With Relapsing Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: temelimab 18 mg/kg|DRUG: temelimab 36 mg/kg|DRUG: temelimab 54 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ARQ-154 Foam in Adolescent and Adult Subjects With Scalp and Body Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Roflumilast foam 0.3%|DRUG: Vehicle foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Treatment Combination for Patients With Unresectable Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Carboplatin/Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
Status: COMPLETED
Conditions: Neuropathic Pain|Chronic Pain|Thoracic Cancer
Interventions: PROCEDURE: thoracic epidural insertion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Aripiprazole to Treat Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole tablet, 5-30mg/day, oral, 6 weeks|DRUG: Risperidone tablet, 1-6mg/day, oral, 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Ibuprofen 400 mg|DRUG: Acetaminophen 650 mg|DRUG: OxyCODONE 5 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myotubular and Centronuclear Myopathy Patient Registry
Status: UNKNOWN
Conditions: Myotubular Myopathy|Myotubular Myopathy 1|Myotubular (Centronuclear) Myopathy|Centronuclear Myopathy|Centronuclear Myopathy, X-Linked|X-linked Myotubular Myopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MR INFORM - MR Perfusion Imaging to Guide Management of Patients With Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Stable Angina|Myocardial Ischaemia
Interventions: PROCEDURE: MR perfusion guidance|PROCEDURE: FFR guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health
Status: COMPLETED
Conditions: Helminthiasis|Diarrhea|Respiratory Infection
Interventions: BEHAVIORAL: Combined water, sanitation, and hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Transversalis Fascia Plane Block and Erector Spinae Plane Blocks in Cesarean Section
Status: UNKNOWN
Conditions: Pain|Postoperative Pain
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Infusion of Donor Plasma in COVID-19 Infection
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: convalescent plasma infusion covid 19
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Adult Participants to Assess the Effects of Ciclosporin Administration on Rilematovir
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rilematovir|DRUG: Ciclosporin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Continuous Infusion Versus Intermittent Bolus Injection of Rocuronium
Status: UNKNOWN
Conditions: Muscle Relaxation|Anesthesia
Interventions: DRUG: Rocuronium Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Investigate the Efficacy and Safety of WX-0593 in ALK Positive Non-Small Cell Lung Cancer (NSCLC) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: WX-0593
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P. Falciparum Infection Dynamics and Transmission to Inform Elimination
Status: UNKNOWN
Conditions: Malaria
Interventions: OTHER: Community Case Management|OTHER: Weekly fever screening and treatment|OTHER: Monthly malaria screening|OTHER: MDA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nevirapine or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir in Human Immunodeficiency Virus (HIV)-1-infected Treatment Naive Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: nevirapine bid|DRUG: nevirapine qd|DRUG: atazanavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System
Status: WITHDRAWN
Conditions: Amputation
Interventions: OTHER: 0 pound tension|OTHER: 2 pound tension|OTHER: 4 pound tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of M-TAPA and TAP Blocks on Postoperative Analgesia in Laparoscopic Inguinal Hernia Surgeries
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: M-TAPA block with bupivacaine 25%|OTHER: TAP block with bupivacaine 25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Immunotherapy Combined With Chemotherapy in Locally Advanced and Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Locally Advanced and Metastatic Pancreatic Cancer
Interventions: DRUG: PD-L1/CTLA4 BsAb|COMBINATION_PRODUCT: GP|COMBINATION_PRODUCT: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ibudilast for Methamphetamine Dependence
Status: COMPLETED
Conditions: Methamphetamine Dependence|HIV Infection
Interventions: DRUG: Ibudilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Family Systems Therapy for Teens With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Childhood Obesity
Interventions: BEHAVIORAL: BFST for Teens with Type 2 Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Flash FFR Ⅱ Study
Status: RECRUITING
Conditions: Coronary Artery Disease|Coronary Stenosis|Myocardial Ischaemia|Coronary Circulation|Stable Angina Pectoris|Unstable Angina Pectoris|Asymptomatic Ischemia|Acute Myocardial Infarction|Percutaneous Coronary Intervention
Interventions: DIAGNOSTIC_TEST: caFFR|DIAGNOSTIC_TEST: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC