pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Personalized Virtual Reality Naturalistic Scenarios in Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Impairment|Cognitive Decline|Cognitive Deterioration|Anxiety State
Interventions: OTHER: Exposure to a Virtual Reality scenarios
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Platelet Enriched Plasma in Preventing Surgery for Patients With Chronic Tympanic Membrane Perforation
Status: TERMINATED
Conditions: Tympanic Membrane Perforation
Interventions: BIOLOGICAL: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Versus Methadone Maintenance in Hepatitis C Patients Receiving Peg-Intron and Rebetol (Study P04279)(TERMINATED)
Status: TERMINATED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: buprenorphine|DRUG: methadone|DRUG: pegylated interferon alfa-2b plus ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: hydroxychloroquine|DRUG: ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Change in Hepatocellular Carcinoma Treated by Thermal Ablation
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: Radiofrequency ablation or microwave ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide W/or W/Out Rituximab and Peripheral Stem Cell Transplantation in Patients With Recurrent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Mechanical Properties of the Healing Achilles Tendon With or Without Early Weightbearing
Status: UNKNOWN
Conditions: Achilles Tendon Rupture|Soft Tissue Injury|Tendon Injury
Interventions: DEVICE: Early weightbearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder
Status: NOT_YET_RECRUITING
Conditions: Borderline Personality Disorder
Interventions: BEHAVIORAL: mindfulness-based Neurofeedback|OTHER: control Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty
Status: UNKNOWN
Conditions: Malnutrition; Protein|Frail Elderly Syndrome
Interventions: DIETARY_SUPPLEMENT: Dietary supplement with protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RE-irradiation of Diffuse MIdline Glioma paTients
Status: NOT_YET_RECRUITING
Conditions: Diffuse Midline Glioma, H3 K27M-Mutant|Diffuse Intrinsic Pontine Glioma|Diffuse Glioma|Pontine Tumors|Thalamic Tumor|Brain Tumor, Pediatric
Interventions: RADIATION: Re-irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy Versus Radiofrequency Ablation for Small Renal Masses
Status: UNKNOWN
Conditions: Small Renal Masses (SRM)
Interventions: PROCEDURE: Radiofrequency Ablation|RADIATION: Stereotactive body radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Multicenter, Open-label Comparison of Preoperative Trastuzumab Emtansine (T-DM1) With or Without Standard Endocrine Therapy vs. Trastuzumab With Standard Endocrine Therapy Given for Twelve Weeks in Patients With Operable HER2+/HR+ Breast Cancer Within the ADAPT Protocol.
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: T-DM1|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonographic Evaluation of Fetal Growth in the Third Trimester of Low-risk Pregnancy: a Randomized Trial
Status: COMPLETED
Conditions: Condition of Fetal Growth or Malnutrition (Diagnosis)
Interventions: DIAGNOSTIC_TEST: Ultrasound 35-36 (6 / 7 days weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy of Listeria in Combination With Chemotherapy as Front-line Treatment for Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: BIOLOGICAL: Immunotherapy plus chemotherapy|BIOLOGICAL: Immunotherapy with cyclophosphamide plus chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Plain Block Versus Fascia Iliac Block
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Quadratus Lumborum plain Block|PROCEDURE: fascia iliaca block|DIAGNOSTIC_TEST: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LLLT for BCRL: a Randomized, Placebo-controlled Study
Status: RECRUITING
Conditions: Breast Cancer Lymphedema
Interventions: DEVICE: Large-area low-level laser therapy(Venusure)|DEVICE: Conventional low-level laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Training on Elderly Resilience
Status: COMPLETED
Conditions: Age Problem|Healthy Aging|Activity, Motor
Interventions: BEHAVIORAL: Resistance training|BEHAVIORAL: Eight-form Yang-style Tai Chi program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Efficacy and Safety of Sepranolone (UC1010) in Patients With Premenstrual Dysphoric Disorder (PMDD)
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder
Interventions: DRUG: Sepranolone (UC1010) low dose|DRUG: Sepranolone (UC1010) high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of AVE5530 in Patients With Primary Hypercholesterolemia
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: AVE5530|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy in Indian Visceral Leishmaniasis
Status: COMPLETED
Conditions: Leishmaniasis, Visceral
Interventions: DRUG: amphotericin B deoxycholate|DRUG: Liposomal Amphotericin B with Miltefosine|DRUG: Liposomal Amphotericin B and Paromomycin Sulfate|DRUG: miltefosine + Paromomycin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coronary Artery and Coronary Artery Bypass Graft Imaging Using a Specialized Catheter and Computed Tomography
Status: WITHDRAWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Placement of an aortic root pigtail catheter.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: TheraSphere With Durvalumab and Tremelimumab for HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: TheraSphere Y-90 glass microsphere therapy|DRUG: Durvalumab (Imfinzi) immunotherapy|DRUG: Tremelimumab immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect on Glycemic Control of Inhaled Insulin Alone or Added to Dual Oral Therapy After Failure of Dual Oral Therapy.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Inhaled Human Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicting Outcome of Transcutaneous Electrical Nerve Stimulator (TENS) in Failed Back Surgery Syndrome
Status: UNKNOWN
Conditions: Failed Back Surgery Syndrome
Interventions: DEVICE: TENS|DEVICE: Sham-TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oropharyngeal and Nasopharyngeal Decontamination With Chlorhexidine Gluconate in the Reduction of the Postoperative Morbidity and Mortality After Major Pulmonary Resections
Status: COMPLETED
Conditions: Infections and Respiratory Infectious
Interventions: DRUG: Chlorhexidine Gluconate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carrageenan Nasal Spray for COVID-19 Prophylaxis
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2
Interventions: DEVICE: Carrageenan nasal and throat spray|DEVICE: Saline nasal and throat spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Recombinant Human Serum Albumin in Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Ascites
Interventions: DRUG: recombinant human serum albumin|DRUG: Human serum albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy
Status: COMPLETED
Conditions: Pediatric Crohn's Disease
Interventions: DRUG: Methotrexate|OTHER: Sugar pill (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Methods of Anesthesia to Achieve a Nerve Block Anesthesia.
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: Echography|OTHER: Echography and neurostimulation|OTHER: Echography, neurostimulation and active mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bulldog vs. Cotton Tourniquet in Laparoscopic Hepatectomy for Patients
Status: UNKNOWN
Conditions: Laparoscopic Liver Resection|Vascular Occlusion|Tourniquet
Interventions: PROCEDURE: BULLDOG ,A Useful Vascular Occlusion Tourniquet In Laparoscopic Liver Resection|PROCEDURE: cotton tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Classical Massage and Benson Relaxation Exercise on Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Symptoms and Signs|Quality of Life
Interventions: BEHAVIORAL: Classical Massage|BEHAVIORAL: Benson Relaxation Exercise|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Smartphone-Based Virtual Reality Relaxation (S-VR) in Cancer Patients Undergoing Chemotherapy
Status: COMPLETED
Conditions: Comfort|Pain|Anxiety|Blood Pressure|Pulse Rate
Interventions: DEVICE: Smartphone-based virtual reality relaxation (SVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium Supplementation in the Second Trimester of Pregnancy to Overweight and Obese Individuals
Status: COMPLETED
Conditions: Gestational Diabetes|Obesity
Interventions: DIETARY_SUPPLEMENT: Magnesium citrate|DIETARY_SUPPLEMENT: Placebo|BEHAVIORAL: Dietary modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantitative Ultrasound Techniques for Diagnosis of Nonalcoholic Steatohepatitis
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver Disease (NAFLD)|Nonalcoholic Steatohepatitis (NASH)
Interventions: DEVICE: Acoustic radiation force impulse (ARFI), magnetic resonance elastography (MRE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: Fluorouracil|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotics as an Adjuvant in Patients With Acute Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis|Inflammatory Bowel Diseases|Acute Severe Colitis
Interventions: DRUG: Ceftriaxone|DRUG: Metronidazole|OTHER: Placebo infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of a Cytochrome P450 2C19 Inhibitor on the Pharmacokinetics of Miricorilant
Status: COMPLETED
Conditions: Antipsychotic Induced Weight Gain|Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: Miricorilant|DRUG: Fluvoxamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation of Peer-support Coaching to Increase Adherence to Online Self-help for College Mental Health
Status: COMPLETED
Conditions: Treatment Adherence
Interventions: BEHAVIORAL: Phone Coaching|BEHAVIORAL: Text Message Coaching|BEHAVIORAL: ACT Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PR-0164 First in Human Clinical Trial of the PAVmed PortIO Intraosseous Infusion System
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Disease stage3|Chronic Kidney Disease stage4|Chronic Kidney Disease Stage 5|Poor Vascular Access
Interventions: DEVICE: PAVmed PortIO™ Intraosseous Infusion System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Manual Medicine or Cognitive Behavioral Therapy With Chronic Uncontrolled Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: CBT/CMT|OTHER: Control group traditional primary care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: General-health-promotion-approach to Promoting Healthier Lives
Status: RECRUITING
Conditions: Health-risk Behaviours|Non Communicable Diseases
Interventions: OTHER: foot-in-the-door technique and self-determination theory|OTHER: Follow-up booster intervention|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab/Tarceva and Tarceva/Sulindac in Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Interventions: DRUG: Bevacizumab|DRUG: erlotinib|DRUG: Sulindac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Vasoconstriction Properties of MC2-01 Cream
Status: COMPLETED
Conditions: Vasoconstriction
Interventions: DRUG: MC2-01 Cream|DRUG: Clobetasol Propionate 0.05% Lotion|DRUG: Betamethasone Dipropionate 0.05% Cream|DRUG: Triamcinolone Acetonide 0.1% Cream|DRUG: Hydrocortisone Butyrate 0.1% Cream|DRUG: Desonide 0.05% Cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-Time Antiretroviral Therapy Adherence Intervention in Uganda
Status: COMPLETED
Conditions: HIV/AIDS|Adherence
Interventions: DEVICE: Fixed SMS, real-time monitoring|DEVICE: Triggered SMS, real-time monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Treatment of Lower Transsphincteric Perianal Fistula: Fistulotomy With Marsupialization vs Open Wound
Status: WITHDRAWN
Conditions: Perianal Fistula|Transsphincteric Anal Fistula
Interventions: PROCEDURE: Fistulotomy with marsupialization|PROCEDURE: Fistulotomy with open wound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EBV Positive Nasopharyngeal Carcinoma Treated With Concurrent Chemo-radiotherapy With or Without Anti-Viral Drug
Status: UNKNOWN
Conditions: Drug Use for Unapproved Schedule
Interventions: DRUG: Acyclovir 800 MG|COMBINATION_PRODUCT: Radiotherapy and chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T-MACS Decision Aid: a Randomized, Controlled Point of Care Trial
Status: WITHDRAWN
Conditions: Heart Attack|Chest Pain|Acute Coronary Syndrome
Interventions: OTHER: Immediate discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Dose-finding Study of JNJ-38877605 in Patients With Advanced or Refractory Solid Tumors.
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: JNJ-38877605
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Papaverine to Prevent Radial Artery Spasm During Transradial Cerebral Angiography
Status: RECRUITING
Conditions: Radial Artery Spasm
Interventions: DRUG: Papaverine Hydrochloride|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Letrozole Pretreatment With Misoprostol Versus Misoprostol Alone in Missed Abortion
Status: UNKNOWN
Conditions: Missed Abortion
Interventions: DRUG: Letrozole then misoprostol|DRUG: placebo then misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
Status: TERMINATED
Conditions: Patent Ductus Arteriosus|Prematurity
Interventions: DRUG: Ibuprofen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Octaray and Pentaray Catheters in Patients Undergoing Ablation for Atrial Tachycardia.
Status: NOT_YET_RECRUITING
Conditions: Atrial Tachycardia
Interventions: DEVICE: Octaray multi-electrode catheter|DEVICE: Pentaray multi-electrode catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2 Trial of a Nicotinic Agonist in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: 3-(2,4 dimethoxybenzylidene anabaseine) 150 mg|DRUG: 3-(2,4 dimethoxybenzylidene anabaseine) 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalteparin, Lenalidomide, and Low-Dose Dexamethasone in Treating Patients With Previously Untreated Multiple Myeloma
Status: TERMINATED
Conditions: Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: dalteparin|DRUG: lenalidomide|DRUG: dexamethasone|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Ultiva (Remifentanil Hydrochloride) in Pediatric Participants General Anesthetised
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula Versus Nasal Continuous Positive Airway Pressure
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: OTHER: Pulmonary Function Testing & esophageal pressure monitoring|OTHER: Pulmonary function testing and esophageal pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Embo Registry; National Registry for Artery Embolization
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Osteoarthritis, Knee|Osteoarthritis Thumb|Osteoarthritis Shoulder|Pain, Chronic|Tendonitis Elbow|Tendonitis Shoulder|Tendonitis;Achilles|Tenosynovitis
Interventions: PROCEDURE: Artery Embolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis
Status: TERMINATED
Conditions: Non-alcoholic Steatohepatitis
Interventions: DRUG: Placebo|DRUG: BFKB8488A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Anti-Proliferative Effects and Genomic Alterations of Abiraterone Acetate Compared to an Aromatase Inhibitor in Post-menopausal HR+ Operable Breast Cancer
Status: WITHDRAWN
Conditions: Post-menopausal ER+ Stage I-IIIA Primary Operable Breast Cancer
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone|DRUG: Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Inotuzumab With Augmented BFM Re-Induction for Patients With Relapsed/Refractory B-cell ALL
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Inotuzumab ozogamicin|DRUG: Prednisone Pill|DRUG: Daunorubicin|DRUG: Vincristine|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Pegaspargase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioural Therapy as a Preventive Treatment for Post Traumatic Stress Disorder
Status: TERMINATED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Modified prolonged exposure therapy|BEHAVIORAL: Attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Yoga Chikitsa for Neck Pain Caused by Cervical Spondylosis
Status: COMPLETED
Conditions: Cervical Spondylosis
Interventions: OTHER: Yoga Chikitsa|DRUG: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dry Blood Spot Screening Test for Biliary Atresia（DBS-SCReBA）
Status: UNKNOWN
Conditions: Hepatobiliary Disease|Biliary Atresia|Neonatal Cholestasis
Interventions: DIAGNOSTIC_TEST: Dry blood spot screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Neoadjuvant Immune Checkpoint Inhibitor in Patients With Resectable Gastrointestinal Cancers
Status: RECRUITING
Conditions: Subjects With Resectable and Localized Gastric Cancer|Subjects With Resectable Esophageal Cancer or Liver Cancer|Subjects With Resectable Liver Cancer
Interventions: DRUG: IMC-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LocalVancomycinPowderToPreventPeriprostheticJointInfection.
Status: NOT_YET_RECRUITING
Conditions: Arthroplasty Complications|Periprosthetic Fracture of Hip
Interventions: DRUG: Vancomycin|PROCEDURE: Total knee or total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Artificial Intelligence Genius® System-assisted Colonoscopy vs. Standard Colonoscopy (COLO-GENIUS)
Status: COMPLETED
Conditions: Colonic Polyp|Colonoscopy|Artificial Intelligence|Colonic Adenoma|Colonic Neoplasms
Interventions: OTHER: Genius® System-assisted Colonoscopy|OTHER: Standard Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Impact of a Personalised Nutrition Intervention in Impaired Glucose Regulation
Status: COMPLETED
Conditions: Pre Diabetes
Interventions: OTHER: DNA-based dietary intervention|OTHER: DNA-based dietary intervention using an app|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antihypertensive Treatment of Acute Cerebral Hemorrhage-II
Status: TERMINATED
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Intravenous nicardipine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prosthetic Foot Test-Drive Strategy for Improving Stability in Veterans With Leg Amputations
Status: RECRUITING
Conditions: Amputation
Interventions: DEVICE: Multiaxial Prosthetic Foot Emulator|DEVICE: Commercially available prosthetic feet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of IW-1701, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Type I or II Achalasia
Status: TERMINATED
Conditions: Achalasia
Interventions: DRUG: Olinciguat|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Blood Flow by PET and N-13 Ammonia During Regadenoson vs Adenosine Stress
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Regadenoson|DRUG: Adenosine|DRUG: N-13 ammonia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-flow Nasal Oxygen Therapy in Hospitalized Infant With Moderate-to-severe Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DEVICE: High-flow nasal canula oxygen therapy|DEVICE: Low-flow oxygen therapy with standard nasal canula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers
Status: RECRUITING
Conditions: Neoplasms|Neoplasm Metastasis|Metastatic Gastrointestinal Carcinoid Tumor
Interventions: DRUG: EMB-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Functional and Emotional Benefits of Replenix Power of Three With Resveratrol
Status: TERMINATED
Conditions: Acne Vulgaris
Interventions: OTHER: Replenix Power of 3 Cream with resveratrol|DRUG: Adapalene and Benzoyl peroxide gel, 0.1%/2.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention to Prevent Behavioral Health Symptoms Among Pandemic Affected Children
Status: RECRUITING
Conditions: Emotional Distress|Prosocial Behavior|Pandemic, COVID-19|Coping Skills|Social Support
Interventions: BEHAVIORAL: JoH-C19|BEHAVIORAL: Switch off Get Active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Poly (ADP-ribose) Polymerase-1 (PARP-1) Inhibitor BSI-201 in Patients With Newly Diagnosed Malignant Glioma
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: bsi-201 plus temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Cancer-related Fatigue, Sexual Dysfunction and Quality of Life in Older Men With Cancer and Androgen Deficiency
Status: RECRUITING
Conditions: Hypogonadism, Male|Cancer|Fatigue
Interventions: DRUG: testosterone 1.62% gel|OTHER: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Cyclophosphamide|DRUG: Azathioprine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps
Status: NOT_YET_RECRUITING
Conditions: Colorectal Carcinoma
Interventions: OTHER: Best Practice|OTHER: Communication Intervention|OTHER: Communication Intervention|OTHER: Communication Intervention|OTHER: Interview|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SIXES: Should I eXtract Every Six? A Study of the Extraction of Permanent Molar Teeth in Children.
Status: TERMINATED
Conditions: Paediatric Dentistry
Interventions: PROCEDURE: Extraction of upper and lower FPM teeth|PROCEDURE: Extraction of lower FPM tooth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Transcranial Direct Current Stimulation on Central Pain in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Neuropathic Pain|Spinal Cord Injury
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Atomic Nano-Generators (Actinium-225-Labeled Humanized Anti-CD33 Monoclonal Antibody HuM195) in Patients With Advanced Myeloid Malignancies
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: ACTINIUM-225-LABELED HUMANIZED ANTI-CD33 MONOCLONAL ANTIBODY HuM195
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2623091 in Participants With High Blood Pressure
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: DRUG: LY2623091|DRUG: Tadalafil|DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Logical Framework for Tailor-made Paradigm Shift Hospital Foodservice to Prevent Malnutrition Among Geriatric Patients in Hospitals
Status: UNKNOWN
Conditions: Hospital Foodservice Satisfaction; Hospital Meals Satisfaction; Elderly, Nutrition, Malnutrition in Elderly, Malnutrition
Interventions: PROCEDURE: MY GERYFS PROTOCOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Intermittent Kangaroo Mother Care Versus Conventional Care Method on Vital Sign and Arterial Oxygen Saturation in Preterm Hospitalized in Neonatal Intensive Care Unit
Status: UNKNOWN
Conditions: Kangaroo Mother Care Method
Interventions: BEHAVIORAL: Intermittent Kangaroo mother care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Construction and Validation of a Score Evaluating the Residual Instability of the Patient After Ankle Ligamentoplasty
Status: COMPLETED
Conditions: Ankle Sprains|Ligament Sprain
Interventions: OTHER: Construction and evaluation of a composite score evaluating post ankle surgery residual instability by completing questionnaires and undergoing physical tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Llama Antibody, Rotavirus Diarrhoea, Children
Status: COMPLETED
Conditions: Male Children|6-24 Months Old With Rotaviral Diarrhoea|Non-cholera Patients
Interventions: DRUG: VHH batch 203027|DRUG: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Neurotization on QoL and Sensory Restoration
Status: NOT_YET_RECRUITING
Conditions: Breast Reconstruction|Neurotization
Interventions: PROCEDURE: Neurotization - Autologous Reconstruction with DIEP/TRAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ⅱ Trial of Camrelizumab in Patients Without Distant Metastasis Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Disease-free Survival Rate
Interventions: DRUG: Camrelizumab+Chemotherapy+Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Gelronate Gel vs. Aloevera in Preventing/Minimizing Radiation-induced Dermatitis in Breast Cancer Patients
Status: COMPLETED
Conditions: Radiation Dermatitis
Interventions: DEVICE: Gelronate|OTHER: Aloevera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel, Topotecan, and Estramustine in Treating Patients With Metastatic Hormone-Refractory Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DRUG: estramustine phosphate sodium|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography
Status: UNKNOWN
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Evolocumab 140 MG/ML [Repatha]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam
Status: COMPLETED
Conditions: Drug Drug Interaction|Warfarin|Midazolam
Interventions: DRUG: ZSP1273
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetics Adviser: Evaluating a Digital Decision Support Tool for Genetic Results
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Genetics ADvISER Decision Aid Plus Standard Genetic Counselling|BEHAVIORAL: Standard Genetic Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Development a Method to Extract Antibiotic Concentration From Interstitial Lung and Epithelial Lining Fluid.
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DIAGNOSTIC_TEST: extraction of ELF and ILF from explanted lung tissue; meropenem concentration in ELF and ILF; ELF on postoperative day 1-5 when bronchoscopy is performed within clinical routine.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Baseline Respiratory Duty Cycles in Subjects With and Without Airway Hyperresponsiveness
Status: COMPLETED
Conditions: Airway Hyper Responsiveness
Interventions: PROCEDURE: Volumetric methacholine challenge unmodified|PROCEDURE: Modified volumetric methacholine challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dynamic Cupping & Myofascial Release on Pain, ROM and Performance in Athletes With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Myofascial Pain|Back Strain
Interventions: DEVICE: Dry Cupping|OTHER: Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: fREEDOM: REsonance for Early Detection Of Breast Cancer Metastases
Status: RECRUITING
Conditions: Invasive Breast Cancer|HER2-positive Breast Cancer|Triple Negative Breast Cancer
Interventions: DIAGNOSTIC_TEST: Diffusion whole body MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan|BIOLOGICAL: Cetuximab|BIOLOGICAL: RAD001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During an Outpatient Palliative Care Visit
Status: COMPLETED
Conditions: Malignant Neoplasms of Independent (Primary) Multiple Sites|Advanced Cancer
Interventions: BEHAVIORAL: Baseline Questionnaires|OTHER: Videos|BEHAVIORAL: Assessment Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Different Methods for Preoxygenation
Status: COMPLETED
Conditions: Anesthesia
Interventions: DEVICE: Humidified high-flow nasal oxygen|DEVICE: Standard nasal cannula|DEVICE: Facemask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Block of the Erector Muscles of the Lumbar Spine to Relieve Acute Lumbar Pain: Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Lumbago
Interventions: DRUG: Ropivacaine and dexamethasone injection solution|DRUG: Sodium Chloride 0.9% Injection Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Health Anxiety: Internet Treatment Versus Face-to-Face Therapy
Status: COMPLETED
Conditions: Severe Health Anxiety|Somatic Symptom Disorder|Illness Anxiety Disorder
Interventions: BEHAVIORAL: CBT, exposure and response prevention (Face-to-face)|BEHAVIORAL: CBT, exposure and response prevention (Internet-based)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma Unclassifiable|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma|Refractory Transformed B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Polatuzumab Vedotin|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gamma-cyclodextrin on the Bioavailability of Ginsenosides
Status: SUSPENDED
Conditions: Drug Absorption
Interventions: DIETARY_SUPPLEMENT: HRG80™ Red Ginseng|COMBINATION_PRODUCT: HRG80™ Red Ginseng + gamma cyclodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 9 Minutes for Tandem Colonoscopy Withdrawal
Status: COMPLETED
Conditions: Colon Polyp|Colorectal Adenoma
Interventions: PROCEDURE: 6-minute then 9-minute withdrawal|PROCEDURE: 9-minute then 6-minute withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Small-cell Lung Cancer|Small Cell Lung Carcinoma
Interventions: DRUG: Onvansertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Steroid Injection in Treating Patients With Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DRUG: Depomedrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test
Status: WITHDRAWN
Conditions: Growth Hormone Deficiency
Interventions: PROCEDURE: 9% Sodium Chloride (NaCl) IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose-ranging, Study of the Safety and Efficacy of Subcutaneous Injections of LIPO-102 Compared With Placebo for the Reduction of Abdominal Subcutaneous Adiposity
Status: COMPLETED
Conditions: Weight
Interventions: DRUG: LIPO-102|DRUG: LIPO-102 Low|DRUG: LIPO-102, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Six-week Integrated Attention Training Program on the Cognitive Functions of Older Adults With Co-occurring Anxiety Symptoms and Subjective Cognitive Complaints
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety
Interventions: BEHAVIORAL: Integrated Attention Training Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy, Tolerability and Pharmacokinetics of NNC 0070-0002-0182 in Overweight or Obese Male and Female Volunteers
Status: TERMINATED
Conditions: Metabolism and Nutrition Disorder|Obesity
Interventions: DRUG: NNC 0070-0002-0182|DRUG: placebo|DRUG: NNC 0070-0002-0182|DRUG: NNC 0070-0002-0182|DRUG: NNC 0070-0002-0182
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasculitis Pregnancy Registry
Status: RECRUITING
Conditions: Vasculitis|Behcet's Disease|CNS Vasculitis|Cryoglobulinemic Vasculitis|Eosinophilic Granulomatosis With Polyangiitis (EGPA)|Churg-Strauss Syndrome (CSS)|Granulomatosis With Polyangiitis (GPA)|Wegener's Granulomatosis|IgA Vasculitis|Henoch-Schoenlein Purpura (HSP)|Microscopic Polyangiitis (MPA)|Polyarteritis Nodosa (PAN)|Takayasu Arteritis (TAK)|Urticarial Vasculitis|Systemic Vasculitis
Interventions: OTHER: Online questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Psilocybin (TRP-8802) in Concert With Psychotherapy in Patients With Irritable Bowel Syndrome (IBS)
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: TRYP-0082|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT