pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of the Safety and Efficacy of Oshadi D and Oshadi R for Cancer Treatment
Status: COMPLETED
Conditions: Tumor|Cancer|Metastasis
Interventions: DRUG: Oshadi D, Oshadi R
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Future Patient - Telerehabilitation of Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure NYHA Class I|Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class IV|Acute Decompensated Heart Failure
Interventions: DEVICE: Telerehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study On Acute Radiotherapy-Induced Oral Mucositis In Patients With Locally Advanced Head And Neck Tumors
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Jeksung combined with anti-radiation spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Optimally Show the Pharmacological Action of Z-100
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Z-100|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rationalisation of Polypharmacy by the Geriatric Consultation Team
Status: COMPLETED
Conditions: Iatrogenic Disease
Interventions: OTHER: Medication review, based on but not limited to the RASP list
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Optimizing Meal and Snack Timing to Promote Health
Status: COMPLETED
Conditions: Dietary Modification
Interventions: DIETARY_SUPPLEMENT: 10 + 20 g protein consumption|OTHER: 30 g protein breakfast|OTHER: 10 g protein breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ad/HER2/Neu Dendritic Cell Cancer Vaccine Testing
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer|Adenocarcinomas|Metastatic Solid Tumors Characterized by HER2/Neu Expression
Interventions: BIOLOGICAL: Adenoviral Transduced Autologous Human Epidermal Growth Factor Receptor (AdHER)2/neu Dendritic Cell (DC) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single Dose Study of E6007 in Healthy Subjects
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: E6007|DRUG: E6007|DRUG: E6007|DRUG: E6007|DRUG: E6007|DRUG: E6007
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2
Status: RECRUITING
Conditions: Malignant Glioma of Brain|Astrocytoma|Malignant Astrocytoma|Oligodendroglioma|Anaplastic Oligodendroglioma of Brain (Diagnosis)|Mixed Oligo-Astrocytoma|Ependymoma|Ganglioglioma|Pylocytic/Pylomyxoid Astrocytoma|Brain Tumor|Glioma|Brain Cancer|Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: rQNestin|DRUG: Cyclophosphamide|PROCEDURE: Stereotactic biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women
Status: COMPLETED
Conditions: Pregnancy Related|Postpartum Sadness
Interventions: BEHAVIORAL: Fourth Trimester Mobile Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Antibiotic Prophylaxis on Incidence of Post-bronchoscopy Fever and Change of Serum Cytokines
Status: COMPLETED
Conditions: Fever|Pneumonia
Interventions: DRUG: oral amoxicillin/clavulanate 1g (875/125mg)|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dornier Aries 2 Extracorporeal Shock Wave Device for the Treatment of Mild Erectile Dysfunction (ED)
Status: TERMINATED
Conditions: Erectile Dysfunction
Interventions: DEVICE: Dornier Aries 2|DEVICE: Placebo / Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy for Prodromal Alzheimer´s Disease With Cerebrovascular Disease
Status: RECRUITING
Conditions: Prodromal Alzheimer's Disease|Cerebral Vascular Disorder|Mild Cognitive Impairment|Vascular Cognitive Impairment
Interventions: DEVICE: Hyperbaric oxygen therapy|DEVICE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: DRUG: gemcitabine hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Placebo-controlled Efficacy Study of IV Ceftriaxone for Refractory Psychosis
Status: TERMINATED
Conditions: Psychosis|Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: ceftriaxone|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With TG4010 in Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: MVA-MUC1-IL2|DRUG: 1st line Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Concentration of MR Contrast in the Arteries
Status: COMPLETED
Conditions: Magnetic Resonance Angiography|Contrast Media
Interventions: OTHER: Standard Injection Rate|OTHER: Patient Tailored Injection Rate|OTHER: gadolinium contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Adjunctive asenapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer, The AtezoCab Trial
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Cabozantinib S-malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary Atherosclerosis
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: OTHER: Patients with ACS|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Effectiveness of OCL 503 in the Treatment of Women With Leiomyomata
Status: COMPLETED
Conditions: Leiomyomata
Interventions: DEVICE: OCL 503 (uterine artery embolization)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior Jaw
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: OsseoSpeed™ length 6 mm|DEVICE: OsseoSpeed™ length 11 mm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: BEHAVIORAL: Diet, Exercise, and Breastfeeding Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Combined Supplementation of Conjugated Linoleic Acid (CLA) and Probiotics (Vivomixx®) as add-on to a First-line Immunotherapy in Relapsing-remitting Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DIETARY_SUPPLEMENT: Vivomixx®|DIETARY_SUPPLEMENT: Conjugated linoleic acid (CLA/Tonalin® FFA 80)|OTHER: Maltose placebo|OTHER: Sunflower oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ctDNA in Adjuvant Chemotherapy of Stage III Colon Cancer (REVISE Trial)
Status: RECRUITING
Conditions: Colon Cancer
Interventions: DRUG: FOLFOXIRI|DRUG: XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluatation of Appscent Device Safety and Effectiveness for Relief of Obstructive Sleep Apnea (OSA) Syndrome in Adults.
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Appscent Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Profile of Plasma Growth Factors Before and After Head and Neck Oncological or Non-oncological Surgery
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Growth Factor|Surgery
Interventions: PROCEDURE: head and neck surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Bromfenac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Oral Azacitidine Compared to Investigator's Choice Therapy in Patients With Relapsed or Refractory AITL
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Angioimmunoblastic T-Cell Lymphoma|Refractory Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Oral azacitidine|DRUG: Romidepsin|DRUG: Bendamustine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Intervention for Socially Anxious College Drinkers
Status: COMPLETED
Conditions: Alcohol Consumption|Alcohol Negative Consequences|Social Anxiety
Interventions: BEHAVIORAL: Brief Intervention for Socially Anxious Drinkers (BISAD)|BEHAVIORAL: Enhanced Alcohol Skills Building and Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Light and Sound Modification on Sleep Quality and Circadian Rhythm in the MICU Patients
Status: COMPLETED
Conditions: Intensive Care Unit|Ventilator|Sleep Quality|Circadian Rhythm
Interventions: BEHAVIORAL: light and sound modification (earplugs and eye masks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Practice Intensity: Comparing Veterans Affairs (VA) to Private Sector Physicians
Status: COMPLETED
Conditions: Physician Survey Response Rates
Interventions: OTHER: $20 cash|OTHER: $50 cash|OTHER: $50 check|OTHER: $100 check
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Pre-Op pregabalin|DRUG: Pre-Op Placebo 1|DRUG: Post-Op pregabalin|DRUG: Post-Op Placebo 1|DRUG: Post-Op Placebo 2|DRUG: Post-Op acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining the Immediate Effects of Counterforce Bracing Versus Kinesiotaping in Patients With Tennis Elbow
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: DEVICE: Kinesiotape|DEVICE: Counterforce elbow brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Alpha-lactalbumin Intake on Metabolic and Cognitive Functions in Elderly
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Alpha-lactalbumin|DIETARY_SUPPLEMENT: Whey|DIETARY_SUPPLEMENT: Casein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Use of ATeGe in Liver Transplant Recipients With Pre-transplant Renal Dysfunction
Status: COMPLETED
Conditions: Renal Insufficiency
Interventions: DRUG: ATeGe-Fresenius
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact on Recurrence Risk of Adjuvant Transarterial Chemoinfusion (TAI) for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: adjuvant transarterial chemoinfusion (TAI)|DRUG: mFOLFOX6 (oxaliplatin, calcium folinate, and 5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thoracic Spine Manipulation on Peripheral Neurodynamic Mobility
Status: COMPLETED
Conditions: Musculoskeletal Manipulations
Interventions: PROCEDURE: Spinal Manual Therapy|PROCEDURE: Spinal Range of Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ertugliflozin 5 mg|DRUG: Ertugliflozin 10 mg|DRUG: Glimerpiride|DRUG: Placebo to Ertugliflozin|DRUG: Placebo to Glimepiride|DRUG: Metformin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, and Pharmacodynamics Study of Single Dose of CNTO 3649 in Healthy Adult Men and Multiple Doses of CNTO 3649 in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Healthy|Diabetes Mellitus, Type 2
Interventions: DRUG: CNTO 3649 10 mcg/kg|DRUG: CNT0 3649 30 mcg/kg|DRUG: CNTO 3649 100 mcg/kg|DRUG: CNTO 3649 300 mcg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deciphering IL-17-dependant Inflammatory Response in Bullous Pemphigoid
Status: RECRUITING
Conditions: Bullous Pemphigoid
Interventions: BIOLOGICAL: Blood sampling|BIOLOGICAL: Liquid bubble sampling|PROCEDURE: Cutaneous biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DRUG: Basal Insulin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Cobiprostone Prevention of NSAID-induced Gastroduodenal Injury
Status: COMPLETED
Conditions: NSAID-induced Gastroduodenal Injury|Ulcers|Rheumatoid Arthritis|Osteoarthritis
Interventions: DRUG: Cobiprostone|DRUG: Placebo|DRUG: Non-steroidal anti-inflammatory drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: alcaftadine 0.25% ophthalmic solution|DRUG: olopatadine 0.2% ophthalmic solution|DRUG: dextran 70 0.1%/hydroxypropyl methylcellulose 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Engaging Clinical Champions to Improve HPV Vaccination
Status: ENROLLING_BY_INVITATION
Conditions: Human Papilloma Virus
Interventions: BEHAVIORAL: Champion Announcement Approach Training|BEHAVIORAL: Traditional Announcement Approach Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The AAA Get Fit Trial: A Pilot Randomised Controlled Trial of Community Based Exercise in Patients With Abdominal Aortic Aneurysms
Status: UNKNOWN
Conditions: Aortic Aneurysm, Abdominal
Interventions: BEHAVIORAL: Community based exercise programme|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study to Evaluate a SARS-CoV-2 mRNA Vaccine in Healthy Adults
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: RBMRNA-176|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy for Insomnia With rTMS
Status: COMPLETED
Conditions: Depression|Insomnia
Interventions: BEHAVIORAL: CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS|DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sitaxsentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A RETROspective Data Collection of comPRESSion Anastomosis Using the ColonRing
Status: UNKNOWN
Conditions: Diverticulum, Colon|Colorectal Neoplasms|Crohn Disease|Colitis, Ulcerative|Colostomy|Ileostomy - Stoma|Rectal Prolapse|Intestinal Polyposis|Lymphoma|Endometriosis|Intestinal Volvulus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Trial of an Acceptance and Commitment Therapy Intervention for Individuals Experiencing Homelessness
Status: COMPLETED
Conditions: Shame|Stigma, Social|Well-Being
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy Group Treatment|BEHAVIORAL: Peer Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangioleiomyomatosis
Status: COMPLETED
Conditions: Lymphangioleiomyomatosis
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Diaphragm Training on Dysphagia in Bulbar Palsy After Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Bulbar Palsy
Interventions: DEVICE: Intermittent Oro-esophageal Tube Feeding|BEHAVIORAL: Diaphragm Training|BEHAVIORAL: Routine rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weeks
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Metastatic Prostate Cancer|Bone Metastases
Interventions: DRUG: Denosumab (reduced dosing)|DRUG: Denosumab (standard dosing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis
Status: RECRUITING
Conditions: Myelofibrosis|Indolent Systemic Mastocytosis
Interventions: DRUG: TL-895|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: DRUG: Sirolimus|OTHER: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RhEGF Incorporated in An Absorbable Collagen Membrane for The Management Of Gingival Recession Defects
Status: UNKNOWN
Conditions: Periodontitis
Interventions: DRUG: RhEGF|DRUG: Plain Collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Study the Effect of Dose of Herpes Simplex Virus-2 (HSV-2) Suppressive Therapy on HSV and HIV
Status: COMPLETED
Conditions: Genital Herpes|HIV Infection
Interventions: DRUG: valacyclovir|DRUG: acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fibers and Gut Health
Status: COMPLETED
Conditions: Constipation
Interventions: OTHER: High quantity fiber|OTHER: Low quantity fiber|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial Investigating the Effect of NN1250 in Young and Elderly Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: insulin degludec|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly
Status: COMPLETED
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Delirium, Dementia, Amnestic, Cognitive Disorders
Interventions: DRUG: Donepezil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exercise Program for Patients With Cervical Dystonia Who Are Treated With Botulinum Toxin Type A
Status: RECRUITING
Conditions: Dystonia, Cervical
Interventions: OTHER: Stretching and Strengthening Exercises|OTHER: Breathing and Rhythmic Coordination Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversal of a Defunctioning Ileostomy 3 Weeks After the Index Operation, RCT
Status: UNKNOWN
Conditions: Colo-rectal Cancer
Interventions: PROCEDURE: Early reversal of a defunctiong ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAP Blockade for Pain Control in One-Anastomosis Gastric Bypass
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Transversus abdominis plane blockade|DRUG: Intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Versus Standard Fractionated Whole Breast Irradiation to Node-negative Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer|Carcinoma in Situ of the Breast
Interventions: RADIATION: standard fractionated radiotherapy|RADIATION: hypofractionated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Non-Squamous Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: pemetrexed|DIETARY_SUPPLEMENT: Folic acid|DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: Vitamin B12|DRUG: dexamethasone|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Eribulin in Her2-negative Metastatic Breast Cancer and Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: HER2-Negative Metastatic Breast Cancer|Recurrent Ovarian Cancer
Interventions: DRUG: Durvalumab|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection and Testing of Respiratory Samples
Status: COMPLETED
Conditions: QIAGEN ResPlex II Advanced Panel|Influenza A|Respiratory Syncytial Virus Infections|Infection Due to Human Parainfluenza Virus 1|Parainfluenza Type 2|Parainfluenza Type 3|Parainfluenza Type 4|Human Metapneumovirus A/B|Rhinovirus|Coxsackie Virus/Echovirus|Adenovirus Types B/C/E|Coronavirus Subtypes 229E|Coronavirus Subtype NL63|Coronavirus Subtype OC43|Coronavirus Subtype HKU1|Human Bocavirus|Artus Influenza A/B RT-PCR Test|Influenza B
Interventions: DEVICE: artus Influenza A/B RT-PCR Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Safety and Tolerability of JS107 in Advanced Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: JS107|COMBINATION_PRODUCT: JS107 combination with Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma
Status: COMPLETED
Conditions: Intrahepatic Cholangiocarcinoma|Combined Hepatocellular and Cholangiocarcinoma
Interventions: DRUG: derazantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon-Alpha for Diabetes Mellitus Type 1
Status: COMPLETED
Conditions: Insulin-Dependent Diabetes Mellitus
Interventions: DRUG: 30,000 units hrINF-alpha|DRUG: 5,000 hrINF-alpha|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics and Pharmacodynamics of MK1809 (1809-001)(COMPLETED)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: MK1809|DRUG: Comparator: Losartan|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Conventional Physical Therapy With and Without Scapular Stabilization Exercises in Adhesive Capsulitis.
Status: UNKNOWN
Conditions: Adhesive Capsulitis
Interventions: OTHER: conventional physiotherapy|OTHER: scapular stabilization exercises along with conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Precise Oncology Interventions in Nutrition and Training (OnPoint)
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Prostate Cancer|Colorectal Cancer
Interventions: OTHER: Fitbit|BEHAVIORAL: Nutrition Course|BEHAVIORAL: Physical Activity Program|BEHAVIORAL: Weekly One on One Session with Registered Dietitian|BEHAVIORAL: Weekly One on One Session with an Exercise Physiologist|BEHAVIORAL: Nutrition Prescription|BEHAVIORAL: Physical Activity Prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ketogenic Diet vs ACTH for the Treatment of Children With West Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Ketogenic Diet|West Syndrome|Infantile Spasm|ACTH
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DRUG: ACTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 25-Gauge Vitrectomy With Ranibizumab or Triamcinolone Acetonide on Proliferative Diabetic Retinopathy in China
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Ranibizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Xa Level With Thromboprophylactic Dosage Nadroparin in Critically Ill COVID-19 and Non-COVID-19 Patients
Status: COMPLETED
Conditions: Critical Illness|Therapeutic Drug Monitoring|Venous Thromboembolism
Interventions: PROCEDURE: blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Follow-up of Broad Spectrum Human Papillomavirus (HPV) Vaccine Study in Women (V503-021)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Cancer|Vulvar Cancer|Vaginal Cancer|Genital Warts|Human Papillomavirus Infection
Interventions: BIOLOGICAL: V503|BIOLOGICAL: GARDASIL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Exposure of High Altitude on Cardiac Output
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: OTHER: Assessment at Low Altitude (470m above sea level)|OTHER: Exposure to High Altitude (2500m above sea level)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of BTX 1503 in Patients With Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BTX 1503|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate PK and Safety of Proellex® in Females With Various Stages of Impaired Renal Function and Healthy Females
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: 50 mg Proellex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Monitoring and Adjustment of Medication Therapy for Patients With Heart Disease
Status: UNKNOWN
Conditions: Coronary Heart Disease|Myocardial Infarction
Interventions: OTHER: Titration of medications|BEHAVIORAL: Lifestyle Counseling|BEHAVIORAL: Medication Counseling|OTHER: Usual Care with Medication Reconciliation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 1, Single Dose, Crossover Study to Determine Bioequivalence and to Investigate Food Effect
Status: COMPLETED
Conditions: Therapeutic Equivalency|Food
Interventions: DRUG: Fesoterodine|DRUG: Fesoterodine|DRUG: Fesoterodine|DRUG: Fesoterodine|DRUG: Fesoterodine|DRUG: Fesoterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Positive-word Stimuli on the Limits of Stability During Multi-direction Reach Operation in Standing Position
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Smartphone Application (SPSRS)|DEVICE: Smartphone Application (YouTube)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous Injection of Erythropoietin on Hepcidin Pharmacokinetics in Healthy Volunteers
Status: UNKNOWN
Conditions: Iron Metabolism Disorders
Interventions: DRUG: Erythropoietin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Status: COMPLETED
Conditions: Vocal Cord Paralysis|Phonasthenia|Presbylarynges|Idiopathic Vocal Cord Paralysis|Ca Larynx
Interventions: PROCEDURE: Prolene Mesh Vocal Cord Medialization Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Left Atrial Appendage Closure by Surgery-2
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Ischemic|Atrial Fibrillation
Interventions: PROCEDURE: closure of the left atrium appendage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lymphadenectomy In Ovarian Neoplasms
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: PROCEDURE: No Lymphadenectomy (LNE)|PROCEDURE: Lymphadenectomy (LNE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block Using Ultrasound Guidance For Treatment Of Post Clipping Cerebral Vasospasm
Status: COMPLETED
Conditions: Cerebral Vasospasm
Interventions: PROCEDURE: Stellate Ganglion Block|DRUG: Bupivacaine|PROCEDURE: Transcranial Doppler|PROCEDURE: Digital Subtraction Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Debio 1450 for Bacterial Skin Infections
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Debio 1450 IV|DRUG: Debio 1450 Oral|DRUG: Linezolid|DRUG: Debio 1450 Oral Placebo|DRUG: Linezolid Placebo|DRUG: Vancomycin IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Brain Tumors Using Labeled Technetium-99m 1-Thio-D-Glucose.
Status: COMPLETED
Conditions: Brain|Neoplasms
Interventions: DRUG: SPECT or SPECT-CT with 99mTc-1-thio-D-glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Utility of Abdominal Ultrasound in the Evaluation of Children With Blunt Trauma
Status: COMPLETED
Conditions: Abdominal Injuries
Interventions: PROCEDURE: Abdominal Ultrasound (FAST examination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Controlled Trial of Losartan in Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: losartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Apixaban 2.5 MG Oral Tablet|DRUG: Enoxaparin 40Mg/0.4mL Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma.
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: BIOLOGICAL: HSV1716 Intra-pleural delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma
Status: RECRUITING
Conditions: Metastatic Urothelial Carcinoma|Bladder Cancer
Interventions: DRUG: Pembrolizumab|PROCEDURE: Cryoablation|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Citicoline in Non-Arteritic Ischemic Optic Neuropathy
Status: COMPLETED
Conditions: Non-arteritic Ischemic Optic Neuropathy
Interventions: DIETARY_SUPPLEMENT: Citicoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological, Cognitive, and Personal Features in the Link Between Placebo-effect and Variability of Pain Reports
Status: RECRUITING
Conditions: Chronic Back Pain
Interventions: OTHER: NaCl 0.9% (normal saline)|OTHER: Magnetized Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study To Assess The Safety And Efficacy Of SU11248 In Patients With Gastrointestinal Stromal Tumor(GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: Placebo|DRUG: SU011248
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irradiated Donor Lymphocyte Infusion Plus High-dose IL-2
Status: TERMINATED
Conditions: Metastatic Malignant Melanoma and Renal Cell Carcinoma
Interventions: BIOLOGICAL: Irradiated donor lymphocyte infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Cisplatin to Neoadjuvant Therapy for T Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Tubular Breast Cancer|Mucinous Breast Cancer|Invasive Ductal Breast Cancer|Inflammatory Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Exergaming in Type 2 Diabetes
Status: COMPLETED
Conditions: Overweight|Obesity|Diabetes Mellitus, Type 2
Interventions: DEVICE: MOBIGAME|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lomecel-B Delivered During Stage II Surgery for Hypoplastic Left Heart Syndrome (ELPIS)
Status: ACTIVE_NOT_RECRUITING
Conditions: HLHS
Interventions: BIOLOGICAL: Longeveron Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.
Status: COMPLETED
Conditions: Dysmetabolic Iron Overload Syndrome|Genetic Hemochromatosis|Iron Absorption|Polyphenols
Interventions: DIETARY_SUPPLEMENT: polyphenols|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Follitropin delta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis
Status: UNKNOWN
Conditions: Henoch-Schonlein Purpura Nephritis
Interventions: DRUG: Qi-Ji Shen-Kang formula; Zhu-Bai formula; Yu-Shen formula|DRUG: angiotensin-converting enzyme (ACE) inhibitor; adrenergic receptor binder (ARB); adrenal cortical hormone; Tripterygium wilfordii polyglycosidium; immunosuppressant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjunctive Ganglionated Plexus Ablation in Redo-Pulmonary Vein Isolation
Status: ACTIVE_NOT_RECRUITING
Conditions: Paroxysmal Atrial Fibrillation|Atrial Fibrillation
Interventions: PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Suicide Prevention by Empowering Adolescents in Pakistan (SEPAK)
Status: COMPLETED
Conditions: Self-harm
Interventions: OTHER: LEADS Plus educational posters|OTHER: Question, Persuade, and Refer (Teachers) Plus educational posters|OTHER: Screening by Professionals programme plus educational posters|OTHER: educational posters|OTHER: Question, Persuade, and Refer (Parents) Plus educational posters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Breath Metabolomics of Placebo Effects, a Pilot Study
Status: COMPLETED
Conditions: Analgesia
Interventions: OTHER: Cold Pressor Test (CPT)|OTHER: Placebo NaCl Nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of and Immune Response to a West Nile Virus Vaccine (WN/DEN4-3'delta30) in Healthy Adults
Status: COMPLETED
Conditions: West Nile Fever Encephalitis
Interventions: BIOLOGICAL: WN/DEN4-3'delta30|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Parenting Skills Intervention in Improving Medication Adherence in Pediatric Cancer Patients
Status: COMPLETED
Conditions: Guardian|Hematologic and Lymphocytic Disorder|Malignant Neoplasm|Parent
Interventions: OTHER: Educational Activity|PROCEDURE: Patient Monitoring|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pedagogues Promoting Positive Parenting in a Home-visiting Program in At-risk Families: A RCT of VIPP-SD
Status: ACTIVE_NOT_RECRUITING
Conditions: Behavior Problems in Early Childhood
Interventions: BEHAVIORAL: VIPP-SD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vitamin D Supplementation in Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Omega-3 Fatty Acids in Dialysis Patients
Status: TERMINATED
Conditions: Cardiovascular Disease
Interventions: DRUG: Omega-3 Acid Ethyl Esters|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sedation and Physiological Effects of Intranasal Dexmedetomidine in Severe COPD
Status: COMPLETED
Conditions: COPD|Sedation|Dexmedetomidine
Interventions: DRUG: Intranasal dexemdetomidine (IN-DEX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Mepolizumab Adjunctive Therapy in Participants With Severe Eosinophilic Asthma on Markers of Asthma Control
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Mepolizumab|DRUG: Placebo|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychologically Informed Education Intervention for Adolescents With Atraumatic Lower-Extremity Injuries
Status: RECRUITING
Conditions: Leg Injury
Interventions: OTHER: Psychologically Informed Education Video Series|OTHER: Anatomy and biomedical education videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myofascial Pain Syndrome and Dextrose Prolotherapy
Status: UNKNOWN
Conditions: Efficacy of Dextrose Prolotherapy in Myofascial Pain Syndrome
Interventions: DRUG: Injection of dextrose, local anesthetic and saline to the myofascial trigger point|DRUG: Local anesthetic and saline injection to the myofascial trigger point
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT