pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vaccine Study for Tick-Borne Encephalitis Virus (TBEV)
Status: TERMINATED
Conditions: Tick-Borne Encephalitis|Encephalitis, Tick-Borne|Tick-Borne Disease|Glycoprotein E, Flavivirus|NSI Protein, Flavivirus
Interventions: BIOLOGICAL: FSME-IMMUN 0.5ml Baxter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services
Status: NOT_YET_RECRUITING
Conditions: Stunting|Gender Equality|Acceptability of Health Care|Diet; Deficiency|Empowerment
Interventions: BEHAVIORAL: Education intervention on nutrition, gender equity, WASH, sexual and reproductive health rights|DIETARY_SUPPLEMENT: school-based iron-folic acid supplement program|BEHAVIORAL: Health service training on equitable access to nutrition, health, and sexual and reproductive services|DIETARY_SUPPLEMENT: bio-fortified crops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase 3, Open-label Study of the Safety and Effectiveness of AA4500 Administered Twice Per Treatment Cycle for up to Four Treatment Cycles (2 x 4) in Men With Peyronie's Disease
Status: COMPLETED
Conditions: Peyronie's Disease
Interventions: BIOLOGICAL: AA4500
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Descemet Endothelial Thickness Comparison Trial
Status: UNKNOWN
Conditions: Keratoplasty|Grafting, Corneal|Transplantation, Corneal|Transplantation, Cornea|Keratoplasty, Lamellar
Interventions: PROCEDURE: DSAEK|PROCEDURE: DMEK|DEVICE: Endoserter|DRUG: Prednisolone|DRUG: Ofloxacin|DRUG: Tropicamide|DRUG: Phenylephrine|DEVICE: Jones Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Intervention for Reducing Sedentary Behaviour Among Prostate Cancer Survivors
Status: RECRUITING
Conditions: Sedentary Behavior|Cancer of Prostate
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: FitBit Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas
Status: COMPLETED
Conditions: Metastatic Sarcoma
Interventions: DRUG: PM01183|DRUG: Doxorubicin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CS0159 in Chinese Patients With PSC (Primary Sclerosing Cholangitis)
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: CS0159 2mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PMZ-1620 (Sovateltide) in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: Normal Saline along with standard treatment|DRUG: PMZ-1620 (sovateltide) along with standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAP Block or Wound Infiltration for Laparoscopic Pediatric Appendectomy: a Pilot Study
Status: UNKNOWN
Conditions: Appendectomy|Laparoscopy|Anesthesia, Conduction|Child, Preschool
Interventions: PROCEDURE: TAP Block|PROCEDURE: LIA local infiltration|PROCEDURE: General anesthesia|DRUG: Postperative analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stenting of the Superficial Femoral and/or Proximal Popliteal Artery Project
Status: COMPLETED
Conditions: Atherosclerosis of Native Arteries of the Extremities
Interventions: DEVICE: The Boston Scientific DES SFA Paclitaxel-Eluting Self-Expanding Stent System (DES SFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Adriamycin|DRUG: Vinblastine|DRUG: Dacarbazine|DRUG: Etoposide|DRUG: Cyclophosphamide|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting Stents to Treat Unprotected Coronary Left Main Disease
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Everolimus-eluting stent (Xience)|DEVICE: Zotarolimus-eluting stent (Endeavor Resolute)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of TU-100 in Patients With Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Digestive System Diseases|Gastrointestinal Diseases|Intestinal Diseases|Abdominal Pain
Interventions: DRUG: Daikenchuto (TU-100)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS)
Status: UNKNOWN
Conditions: Sepsis|Pre-Term|Late-Onset Neonatal Sepsis
Interventions: BIOLOGICAL: Olive Oil Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety of a Live Attenuated Human Parainfluenza Virus Type 2 (HPIV2) Vaccine for Adults, Children, and Infants
Status: COMPLETED
Conditions: Human Parainfluenza Virus 2
Interventions: BIOLOGICAL: Standard Dose HPIV2 Vaccine|BIOLOGICAL: Low dose HPIV2 vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Single and Multiple Dose Study of FPA008 in Healthy Volunteers and Rheumatoid Arthritis Subjects
Status: TERMINATED
Conditions: Healthy|Rheumatoid Arthritis
Interventions: DRUG: FPA008|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Autologous Tumor Lysate-pulsed D-CIK Combined With Chemotherapy for Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer|Neoplasms|Gastrointestinal Neoplasms|Digestive System Neoplasms|Gastrointestinal Diseases
Interventions: DRUG: Chemotherapy|BIOLOGICAL: Ag-D-CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teclistamab or Talquetamab in Combination With Daratumumab for High-Risk Smoldering Myeloma (REVIVE Study)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Teclistamab|DRUG: Talquetamab|DRUG: Daratumumab SC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo Controlled, Randomized, Double Blind Trial of Milnacipran for the Treatment of Idiopathic Neuropathy Pain
Status: TERMINATED
Conditions: Idiopathic Peripheral Neuropathy
Interventions: DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating a Tailored Diuretic Algorithm in Acute Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure Acute
Interventions: OTHER: Urine sodium guided diuretic algorithm|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Study of Stereotactic Radiation Therapy in Patients With High-risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Stereotactic Body Radiotherapy|High-risk|Efficacy|Safety
Interventions: RADIATION: stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Disorders in Bronchiolitis Obliterans Syndrome 2&3
Status: WITHDRAWN
Conditions: Bronchiolitis Obliterans|Sleep Disordered Breathing Central
Interventions: PROCEDURE: Assessment of sleep disorders and treatment if required
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-term Safety Study of MP-513 as Monotherapy or in Combination With Sulfonylurea in Japanese Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin|DRUG: Teneligliptin + Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety, Pharmacokinetics and Clinical Benefit of Silmitasertib (CX-4945) in Subjects With Moderate COVID-19
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Silmitasertib|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Nitrite Infusion for Reversal of Cerebral Vasospasm After Subarachnoid Hemorrhage
Status: TERMINATED
Conditions: Subarachnoid Hemorrhage
Interventions: DRUG: Sodium Nitrite
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hatha Yoga in Breast Cancer Survivors
Status: TERMINATED
Conditions: Breast Carcinoma|Lymphedema
Interventions: PROCEDURE: Yoga|OTHER: tape measurement of arm|OTHER: Quality-of-Life Assessment|OTHER: ldex measurement of arms
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Cord Blood Transplant for Hematologic Malignancy
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma|Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: human myeloid progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Malaria Molecular Surveillance in Mozambique (Phase 2)
Status: RECRUITING
Conditions: Malaria|Falciparum Malaria|Malaria in Pregnancy
Interventions: DIAGNOSTIC_TEST: LDH-based malaria rapid diagnostic test|DIAGNOSTIC_TEST: Malaria rapid diagnostic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate Short-term Efficacy of Palliative Methylphenidate in Asthenia in Advanced Cancer Patients
Status: TERMINATED
Conditions: Asthenia
Interventions: DRUG: methylphenidate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of a Flutter Device and Chest Wall Compression on Respiratory System Impedance in Bronchiectasis Patients
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DEVICE: Flutter|OTHER: Chest Compression|OTHER: Control|OTHER: Impulse Oscillometric|OTHER: Dyspnea scale|OTHER: Acceptability and tolerance|DEVICE: Pulse oximetry|OTHER: Difficulty sputum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 24-week Open-label Study of KPS-0373 in Patients With Spinocerebellar Degeneration (SCD)
Status: COMPLETED
Conditions: Spinocerebellar Degeneration
Interventions: DRUG: KPS-0373, High dose|DRUG: KPS-0373, Low dose
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE
Status: ACTIVE_NOT_RECRUITING
Conditions: Macrophage Activation Syndrome|Secondary Hemophagocytic Lymphohistiocytosis|Still Disease|Systemic Lupus Erythematosus|SJIA|AOSD|MAS
Interventions: DRUG: Emapalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Combined With GemCis Neoadjuvant Therapy of Resectable Intrahepatic Cholangiocarcinoma With High Recurrence Risk
Status: RECRUITING
Conditions: Durvalumab|Intrahepatic Cholangiocarcinoma|Gemcis
Interventions: DRUG: Durvalumab|PROCEDURE: Surgery|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chloroquine in Combination With Carboplatin/Gemcitabine in Advanced Solid Tumors
Status: COMPLETED
Conditions: Malignant Neoplasm|Solid Tumors
Interventions: DRUG: Chloroquine|DRUG: Carboplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 2 or 3 Doses of MenACWY Conjugate Vaccine in Healthy Infants and the Effects of a Booster Dose of MenACWY Administered in the Second Year of Life
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: MenACWY-CRM|BIOLOGICAL: Routine Vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Evaluation of Gastric Volume in Pediatric Patients Undergoing Adenotonsillectomy Surgery
Status: COMPLETED
Conditions: Gastric Volume|Aspiration|Nausea|Bleeding
Interventions: OTHER: gastric assessment of gastric volume
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Aureva Transcranial Ultrasound Device With tPA in Patients With Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: tPA in combination with the Sonolysis Headframe (TUS)|DEVICE: tPA in combination with the Sonolysis Headframe (Sham TUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Vitamin D(25(OH)D) and Omega-3 Fatty Acid (DHA) Enhanced Chicken
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy
Interventions: DIETARY_SUPPLEMENT: DHA/EPA bioenhanced chicken|DIETARY_SUPPLEMENT: 25(OH)D bioenhanced chicken
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multidimensional Inpatient Balance Training Class to Improve Functional Outcomes in Rehabilitation Inpatients With ABI
Status: UNKNOWN
Conditions: Brain Injuries, Traumatic|Cerebrovascular Trauma|Acute Brain Injuries
Interventions: OTHER: Control Balance Training (BT) class|OTHER: Fallproof Balance Training (BT) class
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fracture Healing Assessed by HR-pQCT After Administration of Calcium and Vitamin D
Status: COMPLETED
Conditions: Bone Fracture
Interventions: DIETARY_SUPPLEMENT: Calcium|DIETARY_SUPPLEMENT: Calcium + low dose vitamin D|DIETARY_SUPPLEMENT: Calcium + high dose vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase I Study of the Proteosome Inhibitor CEP 18770 in Patients With Solid Tumours or Non-Hodgkin's Lymphomas
Status: COMPLETED
Conditions: Solid Tumors|Lymphoma, Non-Hodgkin
Interventions: DRUG: CEP-18770
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchoscopic Intrabullous Autologous Blood Instillation (BIABI) for Emphysema
Status: UNKNOWN
Conditions: Bullous Emphysema
Interventions: PROCEDURE: Bronchoscopic intrabullous autologous blood instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Warning and Optimization Strategy in Carotid Endarterectomy
Status: UNKNOWN
Conditions: Carotid Stenosis|Carotid Artery Diseases|Stroke|Vascular Diseases
Interventions: PROCEDURE: CEA and TCD monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Catheter-Related-Bladder Discomfort After Transurethral Surgery
Status: RECRUITING
Conditions: Catheter-related-bladder Discomfort
Interventions: OTHER: Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Increase in Chest Wall Elastance as an Alternative to Prone Positioning in Moderate-to-severe ARDS.
Status: SUSPENDED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DEVICE: weight on the anterior chest of the patient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparative Assessment of Mycological Efficacy, Safety, Recurrence, and Cost-effectiveness of Selenium Sulfide 1.8% Shampoo Versus Ketoconazole 2% Shampoo in Pityriasis Versicolor: a Double-blind Randomized Controlled Trial
Status: COMPLETED
Conditions: Pityriasis Versicolor
Interventions: DRUG: shampoo with different composition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Panitumumab for Intravenous Infusion 100 mg and 400 mg Special Drug Use Surveillance "Survey on Unresectable, Advanced or Recurrent Colorectal Cancer With Wild-type KRAS Gene" (All-patient Surveillance)
Status: COMPLETED
Conditions: Advanced or Recurrent Colorectal Cancer
Interventions: DRUG: Panitumumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Gum Chewing on Bowel Cleansing Before Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation Scale|Adenoma Detection Rate
Interventions: DIETARY_SUPPLEMENT: gum+PEG|DRUG: polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy Study of Vaginal Misoprostol for Cervical Ripening and Induction of Labor
Status: COMPLETED
Conditions: Cervical Ripening|Induction of Labor
Interventions: DRUG: Placebo|DRUG: Misoprostol vaginal Tablet 25 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Sedation With Third Molar Surgery
Status: TERMINATED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate the Efficacy and Safety of Relugolix (TAK-385) 40 mg Compared With Leuprorelin in the Treatment of Uterine Fibroids
Status: COMPLETED
Conditions: Uterine Fibroids
Interventions: DRUG: Relugolix|DRUG: Relugolix Placebo|DRUG: Leuprorelin|DRUG: Leuprorelin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: CU06-1004, Single dose|DRUG: CU06-1004, Multiple doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Subcutaneous Glucagon Before, During and After Exercise a Study in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Glucagon before exercise|DRUG: Glucagon after exercise|DRUG: Glucagon after resting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients With Solid Tumors or Lymphoma
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: melphalan|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: bone marrow ablation with stem cell support|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus Camrelizumab and HAIC in the Treatment of Non-MSI-H Advanced Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer
Interventions: DRUG: combination therapy Combination: Fruquintinib plus Camrelizumab and HAIC (TOMOX/TOMIRI) Maintenance: Fruquintinib plus Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Japanese Subjects
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: biphasic insulin aspart 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Plus Oxaliplatin Versus Oxaliplatin Plus Fluorouracil/Leucovorin for Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: GEMOX|DRUG: FOLFOX4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Nutrition Status and Digestive Conditions by Using Oral Nutritional Supplementation on Children in Vietnam
Status: UNKNOWN
Conditions: Undernutrition|Wasting|Malnourished
Interventions: DIETARY_SUPPLEMENT: Kazu Gain Gold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Oral Treatments for Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: SOF/LDV (sofosbuvir/ledipasvir)|DRUG: PrOD (ombitasvir/paritaprevir/ritonavir with dasabuvir) (Phase 1 only)|DRUG: EBR/GZR (elbasvir/grazoprevir)|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INSULIN GLARGINE (HOE901)|DRUG: Insulin Glulisine|DRUG: Biphasic insulin aspart 30|DRUG: Repaglinide|DRUG: Acarbose|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visual Outcomes And Contrast Sensitivity After Myopic Wavefront-Optimized Lasik With Nexisvision Shield Or Bandage Contact Lens
Status: WITHDRAWN
Conditions: Myopia
Interventions: DEVICE: Nexisvision shield
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cerebral Elastography by Magnetic Resonance: Comparison of Healthy Subjects and Patients With Glial Tumor
Status: UNKNOWN
Conditions: Elasticity Imaging Techniques
Interventions: DIAGNOSTIC_TEST: Device for mechanical excitation by pressure waves
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cilnidipine Effect on High Blood Pressure and Cerebral Perfusion in Ischemic Stroke Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension|Stroke
Interventions: DRUG: cilnidipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Pembrolizumab With Dual MAPK Pathway Inhibition Plus Pembrolizumab in Melanoma Patients
Status: UNKNOWN
Conditions: Metastatic Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Dabrafenib|DRUG: Trametinib|PROCEDURE: Biopsy|PROCEDURE: Blood taking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tocilizumab on Patients With COVID-19
Status: COMPLETED
Conditions: SARS-CoV 2
Interventions: DRUG: Tocilizumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Principle Study of Ondansetron for the Prevention of Vasovagal Syncope: The Eleventh Prevention of Syncope Trial (POST11)
Status: RECRUITING
Conditions: Vasovagal Syncope (VVS)|Syncope
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution
Status: COMPLETED
Conditions: Refractive Ametropia
Interventions: DEVICE: BL-3100-NBR03 multi-purpose solution|DEVICE: renu® Advanced Formula multi-purpose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Immunity to Specific Microbial Antigens in Healthy Smokers and Non-smokers and in Subjects With Stable COPD
Status: COMPLETED
Conditions: Respiratory Disorders
Interventions: PROCEDURE: Blood collection|PROCEDURE: Swab collection|PROCEDURE: Sputum collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial
Status: TERMINATED
Conditions: Hypogonadism|Hypogonadism, Male|Hypogonadotropic Hypogonadism
Interventions: DRUG: Letrozole 2.5mg, hCG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and Diabetic Retinopathy
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Studying Genes in Samples From Younger Patients With Desmoplastic Small Round Cell Tumor Registered on COG-D9902 or COG-ABTR01B1
Status: COMPLETED
Conditions: Sarcoma
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: nucleic acid sequencing|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients
Status: COMPLETED
Conditions: Aspergillosis|Candidiasis|Fungemia|Mycoses
Interventions: DRUG: FK463|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Non-invasive Ventilation in Patients Undergoing Heart Surgery
Status: RECRUITING
Conditions: Cardiac Surgical Procedures|Continuous Positive Airway Pressure|BIPAP Biphasic Intermittent Positive Airway Pressure
Interventions: PROCEDURE: CPAP|PROCEDURE: BIPAP|PROCEDURE: Usual care in phisicaltherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study on the Efficacy and Safety of Procaterol Versus Salbutamol Given Via Metered Dose Inhaler With Spacer in the Management of Acute Asthma Attack in the Emergency Room
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Procaterol|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed With Dry Eye Disease in A Sample of Egyptian Patients
Status: RECRUITING
Conditions: Dryness|Dry Eye Syndromes|Meibomian Gland Dysfunction
Interventions: DEVICE: Dry eye device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Two Hyaluronic Acids in Osteoarthritis of the Knee
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: 3ml hyaluronic acid (DUROLANE)|DEVICE: 2ml hyaluronic acid, (HYALGAN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FAB Programme for Parents of Children With NDD
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Neurodevelopmental Disorders|Intellectual Disability|Specific Learning Disorder|Communication Disorders|Motor Disorders
Interventions: BEHAVIORAL: Facilitator-guided Acceptance and Commitment Bibliotherapy (FAB)|BEHAVIORAL: General Parenting Education and Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care
Status: ENROLLING_BY_INVITATION
Conditions: Gynecologic Cancer
Interventions: OTHER: Online education|OTHER: Regular standard of care education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Esketamine on 95% Induction Dose of Remimazolam
Status: NOT_YET_RECRUITING
Conditions: Pediatric|Gastroscopy|ED95|Sedation
Interventions: DRUG: Remimazolam besylate and low-dose Esketamine|DRUG: Remimazolam besylate and Medium dose Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effects of Coreg CR and Coreg IR on Heart Function in Subjects With Stable Chronic Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: carvedilol controlled release|DRUG: carvedilol immediate release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prostate Cancer Patients Treated With Alternative Radiation Oncology Strategies
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionated radiotherapy with photons|RADIATION: Hypofractionated radiotherapy with protons|RADIATION: Normofractionated radiotherapy with photons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Olive Leaf Extract Administration on Cardiovascular Health
Status: COMPLETED
Conditions: Overweight and Obesity|Elevated Cholesterol
Interventions: DIETARY_SUPPLEMENT: OLECOL|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Transanal Transection and Single-Stapled anastomosis (TTSS)|PROCEDURE: Double-stapled anastomosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of a Pre-packaged, Portion Controlled Meal Plan on Type 2 Diabetes and Glycemic Control: A Comparison Study
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Portion controlled diet|OTHER: Diabetes Support and Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GATT-Patch Versus SURGICEL® Original in Minimally Invasive Liver and Gallbladder Surgery
Status: RECRUITING
Conditions: Intraoperative Bleeding|Liver Diseases|Gallbladder Diseases|Hemorrhage, Surgical
Interventions: DEVICE: GATT-Patch|DEVICE: SURGICEL® Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neurogenic Mechanisms in Burning Mouth Syndrome
Status: COMPLETED
Conditions: Burning Mouth Syndrome
Interventions: OTHER: Capsaicin oral gel 0.025%|OTHER: Capsaicin oral gel 0.01%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sentinel Lymph Node Detection in Patients With Stage Ib-III Melanoma Using MSOT and ICG
Status: UNKNOWN
Conditions: Melanoma, Stage I|Melanoma, Stage II|Melanoma Stage III
Interventions: DEVICE: MSOT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Shigyakusan Used for IBS and MUPS Diagnosed by Abdominal N Line Tenderness
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Tsumura's shigyakusan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GM03 - Platelet RNA Signatures of Aspirin
Status: COMPLETED
Conditions: Platelet Aggregation Inhibitors|Aspirin|Ticagrelor|RNA
Interventions: DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surufatinib Combined With Toripalimab and Chemotherapy in the Treatment of Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Surufatinib,Toripalimab,Pemetrexed,Carboplatin/Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Eating Behaviour and Sense of Taste Before and After Treatment With Nocturnal Continuous Positive Airway Pressure in Overweight Patients With Obstructive Sleep Apnea Syndrome.
Status: COMPLETED
Conditions: Obesity|Obstructive Sleep Apnoea Syndrome
Interventions: OTHER: questionnaires|DEVICE: wrist actimeter|BIOLOGICAL: Blood samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cap/Iri Plus Cetuximab Compared to Cap/ox Plus Cetuximab in Patients With Metastatic Colorectal Cancer.
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: irinotecan|DRUG: oxaliplatin|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tamiflu (Oseltamivir) for Treatment of Influenza With a Focus on (H1N1) 2009 Flu Strain
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Oseltamivir|DRUG: Oseltamivir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fructans, Lactitol and Lactose in Minimal Hepatic Encephalopathy
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Red cereal bar|DIETARY_SUPPLEMENT: Green cereal bar|DIETARY_SUPPLEMENT: White cereal bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracoscopy for Idiopathic Pneumothorax in Children
Status: COMPLETED
Conditions: Spontaneous Pneumothorax|Idiopathic Pneumothorax|Bleb Lung|Child, Only
Interventions: OTHER: Video-Assisted Thoracoscopy with blebectomy and pleural abrasion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention
Status: RECRUITING
Conditions: Coronary Artery Disease|Dyslipidemias|Primary Prevention
Interventions: DRUG: Combination drug group of Ezetimibe 10 mg/Rosuvastatin 5 mg|DRUG: Mono drug group of Rosuvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ozone Gel on Treatment of Chronic Periodontitis
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: scaling and root planing|DRUG: placebo gel|DRUG: Ozonated olive oil gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Detection and Prognostic Value of Recurrent XPO1 Mutations of Patients With Classical Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Classical Hodgkin Lymphoma
Interventions: OTHER: Digital Polymerase Chain Reaction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study on Regeneration of Skin Defects in Diabetic Ulcers Treated With New Electrospun Material PLCL/Fg
Status: RECRUITING
Conditions: Diabetic Foot
Interventions: DRUG: PLCL/Fg group|DRUG: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Sunitinib Malate in Treating Patients With Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Recurrent Fallopian Tube Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Primary Peritoneal Cavity Cancer|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Epithelial Cancer|Stage IIIA Primary Peritoneal Cavity Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Epithelial Cancer|Stage IIIB Primary Peritoneal Cavity Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Epithelial Cancer|Stage IIIC Primary Peritoneal Cavity Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Primary Peritoneal Cavity Cancer
Interventions: DRUG: sunitinib malate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Oral FB-101 in Healthy Subjects
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: FB-101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CART-19 Immunotherapy in Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Hematopoietic/Lymphoid Cancer|Non-hodgkin Lymphoma,B Cell|Mantle Cell Lymphoma
Interventions: BIOLOGICAL: anti-CD19-CAR vector-transduced T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Reduction in Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: BEHAVIORAL: smoking cessation|DRUG: betablocker, diuretics, ACEI, ARB,|DRUG: statins, ezetimibe|BEHAVIORAL: training|BIOLOGICAL: influenza vaccine|DRUG: metformin, glimepiride, insulin|BEHAVIORAL: weight reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate-Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sinovac, H1N1 Vaccine + Trivalent Inactivated Influenza Vaccine, Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: H1N1 influenza A Vaccine (PANFLU.1)|BIOLOGICAL: Trivalent Inactivated Influenza Vaccine (ANFLU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Study of Intraoperative Administration of CA-008 for the Correction of Hallux Valgus Deformity
Status: COMPLETED
Conditions: Hallux Valgus Deformity
Interventions: DRUG: CA-008|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Prostate Cancer
Interventions: DRUG: Tarlatamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient and Physician Intervention to Increase Organ Donation
Status: COMPLETED
Conditions: Tissue and Organ Donation|Communication
Interventions: BEHAVIORAL: Participant Video and Provider Cueing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma
Status: SUSPENDED
Conditions: Metastatic Cancer|Renal Cancer
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Entinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
Status: RECRUITING
Conditions: Lysosomal Diseases|Gangliosidosis|GM1
Interventions: BIOLOGICAL: AAV9-GLB1|PROCEDURE: Abdominal ultrasound|DRUG: Rituximab|DRUG: Sirolimus|DRUG: Methylprednisolone|DRUG: Prednisone|DIAGNOSTIC_TEST: Audiology assessment with ABR|DIAGNOSTIC_TEST: Bone density scan (DEXA)|DIAGNOSTIC_TEST: Electrocardiogram (EKG)|DIAGNOSTIC_TEST: Echocardiogram|OTHER: Electroencephalogram (EEG) awake and extended overnight|DIAGNOSTIC_TEST: Laboratory tests|PROCEDURE: Lumbar puncture|PROCEDURE: Brain MRI/MRS/fMRI|BEHAVIORAL: Neurocognitive testing|OTHER: Neurology exam|BEHAVIORAL: PICC or other Central line placement|PROCEDURE: Skeletal survey|PROCEDURE: Skin biopsy|PROCEDURE: Speech and modified barium swallow study|PROCEDURE: Ophthalmology exam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Pentaxim™ in an Indian Population
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Polio|Pertussis|Haemophilus Infections
Interventions: BIOLOGICAL: Diphteria/Tetanus/Polio/Acellular Pertussis/Hib vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Starch Digestibility and Amylase Sufficiency in Children
Status: COMPLETED
Conditions: Malnutrition, Child
Interventions: OTHER: Normal sorghum porridge, algal starch|OTHER: Normal sorghum porridge, algal dextrins|OTHER: Normal sorghum porridge, labeled flour|OTHER: Modified sorghum porridge, labeled flour|OTHER: Thinned sorghum porridge, labeled flour|OTHER: Modified sorghum porridge, octanoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: CIETAI and Sequential Radiotherapy in Squamous Lung Cancer
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: bronchial artery interventional therapy|DRUG: Chemotherapy drug|RADIATION: IMRT|DRUG: Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT