pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tralokinumab in Combination With Topical Corticosteroids in Japanese Subjects With Moderate-to-severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tralokinumab|DRUG: Placebo|OTHER: Topical corticosteroids (TCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: XLIMus Drug Eluting Stent: a randomIzed Controlled Trial to Assess Endothelization
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Xlimus DES Implantation during coronary angioplasty|DEVICE: Synergy DES Implantation during coronary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Vinorelbine Plus Cisplatin(NP) Versus NP Plus Endostar in Patients With Completely Resected Stage IB-IIIA Non-small Cell Lung Cancer(NSCLC)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: recombinant human endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study.
Status: COMPLETED
Conditions: Diarrhea|HIV Infections
Interventions: DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on the Effectiveness of Herbal Medicinal Mixture in Parkinson Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Herbal Medicinal Mixture (Roucongrong, Heshouwu etc.)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the New Viviscal Professional Strength Oral Supplement in Females With Thinning Hair
Status: COMPLETED
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: New Viviscal Professional Supplement|DIETARY_SUPPLEMENT: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Plus Cisplatin Versus Gemcitabine Plus Cisplatin for Advanced NSCLC Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Efficacy
Interventions: DRUG: cisplatin, dexamethasone,vitamin B12, folic acid|DRUG: cisplatin, gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Informed Consent for Whole Genome Sequencing: Ideals and Norms Referenced by Early Participants
Status: COMPLETED
Conditions: Coronary Artery Disease|Proteus Syndrome|Coffin - Sins Syndrome|Familial Isolated Hyperparathyroidism|Dubouitz Syndrome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Bumetanide Oral Liquid Formulation in Children Aged From 2 to Less Than 7 Years Old With Autism Spectrum Disorder.
Status: TERMINATED
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: BUMETANIDE (S95008) for week 0 - 26|DRUG: PLACEBO for week 0 - 26|DRUG: Open-Label BUMETANIDE (S95008) for weeks 26 - 52
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Cefzil 250 mg/5 ml Cefprozil Oral Suspension Following a 10 ml Dose Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Cefprozil 250 mg/5 ml Oral Suspension (Sandoz GmbH)|DRUG: Cefzil (Cefprozil) 250 mg/5 ml Oral Suspension (Bristol-Myers Squibb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults
Status: COMPLETED
Conditions: Obesity|Hypercholesterolemia|Hyperglycemia|Hypertriglyceridemia
Interventions: OTHER: Mediterranean Lemonade|OTHER: Green Tea|OTHER: Flavored Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Platelet Rich Plasma and Alternative Therapies for the Treatment of Tennis Elbow (Lateral Epicondylitis)
Status: TERMINATED
Conditions: Lateral Epicondylitis (Tennis Elbow)
Interventions: OTHER: Platelet Rich Plasma (PRP) Injection|OTHER: Whole Blood Injection|OTHER: Dry Needle Fenestration|OTHER: Sham Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Training in Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DEVICE: High-intensity IMT|DEVICE: Sham High-intensity IMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of the L3-L4 Intervertebral Space in Obese Parturients
Status: COMPLETED
Conditions: Pregnancy|Obesity|Obstetrical Anesthesia
Interventions: PROCEDURE: L3-L4 location: Palpation method confirmed by US
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Perioperative Analgesic Efficiency of Bilateral Superficial Cervical Plexus Block in Patients With Thyroidectomy
Status: COMPLETED
Conditions: Block
Interventions: PROCEDURE: Bilateral superficial cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transient Elastography in Hepatectomy for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Surgery|Hepatocellular Carcinoma
Interventions: PROCEDURE: FibroScan (Transient Elastography measurement)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Placebo-Controlled Phase 3 Trial of Repeated Lamazym Treatment of Subjects With Alpha-Mannosidosis
Status: COMPLETED
Conditions: Alpha-Mannosidosis
Interventions: DRUG: Lamazym|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Carfilzomib Plus Dexamethasone in Adults With Relapsed or Refractory Multiple Myeloma at US Community Oncology Centers
Status: TERMINATED
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers
Status: RECRUITING
Conditions: Fatigue|Stress, Job
Interventions: DIETARY_SUPPLEMENT: Lactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress)|DIETARY_SUPPLEMENT: Starch (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Efficacy of Tacrolimus + Methotrexate Versus Placebo + Methotrexate in Treatment of Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tacrolimus (Prograf®)|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trunk Control Tests in Post-stroke Context: Validity and Reliability Study
Status: COMPLETED
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Trunk strength with hand-held dynamometer|DIAGNOSTIC_TEST: Balance Assessment in Sitting and Standing test (BASS)|DIAGNOSTIC_TEST: Timed Up and Go test|DIAGNOSTIC_TEST: Modified Functional Reach Test (MFRT)|DIAGNOSTIC_TEST: Joint Position sense test (trunk)|DIAGNOSTIC_TEST: Unstable sitting in a seesaw
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Different Fat Enriched Meats on the Hepatic Cholesterol Synthesis
Status: COMPLETED
Conditions: Lipid Metabolism Disorders|Sterols|Diet, High-Fat|Cholesterol|Fatty Acids|Hyperlipidemias
Interventions: BEHAVIORAL: Changes in cholesterol metabolism|OTHER: Lean red meat diet|OTHER: Fat red meat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of TMC435350 Administered With or Without Standard of Care Therapy in Participants With Genotype 1 Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: TMC435|DRUG: Placebo|DRUG: Peginterferon (PegIFNα-2a)|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer|Cholangiocarcinoma|Gallbladder Cancer|Intrahepatic Cholangiocarcinoma|Perihilar Cholangiocarcinoma|Extrahepatic Cholangiocarcinoma|Hilar Cholangiocarcinoma|Distal Bile Duct Cancer
Interventions: DIAGNOSTIC_TEST: Multi-Platform Profiling with Organoid Drug Sensitivity Screening and ctDNA Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Empiric Treatment for Acute HIV in the ED
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute HIV Infection
Interventions: DRUG: Bictegravir 50mg+Tenofovir AF 25 mg+emtricitabine 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BE Study of Calcipotriene Hydrate and Betamethasone Dipropionate Topical Suspension in the Treatment of Scalp Psoriasis
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: Calcipotriene and betamethasone suspension|DRUG: Taclonex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Different Endoscopic Entry Techniques on Postoperative Gastrointestinal Function
Status: UNKNOWN
Conditions: Gastrointestinal Disorder Postoperative
Interventions: OTHER: direct trocar entry|OTHER: veres needle entry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Study on Efficacy and Safety in Subjects Using Levemir® for the Treatment of Insulin Dependent Type 1 or Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Behavioral and Analgesic Trial for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Tramadol|DRUG: Placebo|BEHAVIORAL: Cognitive Behavior Therapy for FM|BEHAVIORAL: Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-T Re-treatment for Refractory/Relapsed Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma|Multiple Myeloma in Relapse|Multiple Myeloma Progression
Interventions: DRUG: CAR-T Re-treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo Controlled, Two-Period Cross-Over, Proof of Activity Study to Evaluate the Effects of TAK-041 on Motivational Anhedonia as Add-On to Antipsychotics in Participants With Stable Schizophrenia
Status: COMPLETED
Conditions: Stable Schizophrenia
Interventions: DRUG: TAK-041|DRUG: Placebo|DRUG: Second Generation Antipsychotics (SGA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Adrenal Function of Budesonide Versus Fluticasone in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: budesonide / formoterol|DRUG: fluticasone/salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Medication Self-management Intervention in the Improvement of Medication Adherence
Status: NOT_YET_RECRUITING
Conditions: Heart Diseases|CKD|Diabetes|Cancer|Asthma|Thyroid|Hypertension
Interventions: BEHAVIORAL: Motivational tteaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Research a New Predictive Marker of Intraventricular Hemorrhage in Very Preterm Infants
Status: UNKNOWN
Conditions: Intraventricular Hemorrhage
Interventions: DEVICE: Standard cranial echography|PROCEDURE: Cord blood analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 1 Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: OSI-906|DRUG: erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study To Estimate The Effect Of Tafamidis On Rosuvastatin Pharmacokinetics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: tafamidis|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid Cancer
Status: COMPLETED
Conditions: Thyroid Cancer
Interventions: DRUG: Temsirolimus and Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalization of Immunosuppressive Treatment for Organ Transplant Recipients
Status: TERMINATED
Conditions: Kidney Injury|Kidney Failure|Kidney Failure, Chronic|Kidney Failure, Acute|Kidney Diseases|Kidney Transplant Rejection|Kidney Transplant Infection|Kidney Transplant; Complications|Kidney Disease, Chronic|Kidney Ischemia
Interventions: DIAGNOSTIC_TEST: AlloSure|DIAGNOSTIC_TEST: PAXGene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Oral Nanocurcumin as an Adjuvant Therapy for Anogenital Warts: Evaluation of Clinical Improvement, NFĸB, IFN-γ, and FOXP3+TReg From Lesions Tissue
Status: COMPLETED
Conditions: Anogenital Wart
Interventions: DRUG: Curcumin Oral Capsule|DRUG: Trichloroacetic acid|PROCEDURE: Blood sample collection|PROCEDURE: Cotton swab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Preventive Analgesia Improve the Outcome of Demerol-Vistaril Procedural Sedations in Pediatric Dentistry
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: oral placebo|DRUG: Oral Analgesics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of UV-induced Carcinogenic Skin Alterations in Immunosuppressed Solid Organ Transplanted Patients
Status: TERMINATED
Conditions: Actinic Keratoses|Squamous Cell Carcinomas
Interventions: DEVICE: MD-3511356|OTHER: Standard Sun Protection Measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Physical Activity Counselling on the Severity of Chronic Low Back Pain in Patients With Cardiovascular Risk
Status: COMPLETED
Conditions: Low Back Pain|Physical Activity
Interventions: BEHAVIORAL: Physical Activity Counselling|OTHER: Therapeutic Exercise for LBP|OTHER: Superficial Thermotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 2 Emphysema Study
Status: COMPLETED
Conditions: Pulmonary Emphysema
Interventions: BIOLOGICAL: BLVR Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock-wave Therapy for Supraspinatus Calcifying Tendonitis: a Randomized Clinical Trial Comparing Two Different Energy Levels
Status: COMPLETED
Conditions: Supraspinatus Calcifying Tendonitis
Interventions: DEVICE: Extracorporeal shock wave therapy STORZ MEDICAL Modulith SLK|DEVICE: Extracorporeal shock wave therapy STORZ MEDICAL Modulith SLK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
Status: COMPLETED
Conditions: Genetic Disorders
Interventions: DRUG: i.v. recombinant human C1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brazilian HIV/Sexually Transmitted Infection (STI) Prevention for Adolescents With Mental Health Disorder
Status: COMPLETED
Conditions: HIV|Sexually Transmitted Infection|Pregnancy
Interventions: BEHAVIORAL: STYLE Brazil|BEHAVIORAL: Health Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: PTK787/ZK 222584|DRUG: Temozolomide|PROCEDURE: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate CryoBalloon™ Full and Swipe Ablation Systems for Ablation of Human Esophageal Epithelium
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DEVICE: CryoBalloon™ Full Ablation System|DEVICE: CryoBalloon™ Swipe Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of LGX818 in Patients With Advanced or Metastatic BRAF V600 Mutant NSCLC
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: LGX818
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of MBF-015 in Huntington's Disease Patients
Status: RECRUITING
Conditions: Huntington Disease
Interventions: DRUG: MBF-015 16 mg oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Zirconomer Restorative
Status: NOT_YET_RECRUITING
Conditions: Dental Caries in Children|Dental Materials
Interventions: OTHER: zirconia reinforced glass ionomer|OTHER: Glass ionomer cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability and Pharmacokinetics of LNA043 in Japanese Osteoarthritis Participants
Status: COMPLETED
Conditions: Osteoarthritis|Knee
Interventions: DRUG: LNA043|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of High Dose Carfilzomib in Multiple Myeloma Patients Who Have Progressed On Standard Dose Carfilzomib
Status: COMPLETED
Conditions: Relapse Multiple Myeloma|Refractory Multiple Myeloma
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effect of Adaptive Posture-balance Cardiac Rehabilitation Exercise on Cardiovascular Diseases
Status: COMPLETED
Conditions: Cardiac Rehabilitation|Exercise Therapy|Balance Exercises|Cardiovascular Diseases
Interventions: BEHAVIORAL: Adaptive posture-balance cardiac rehabilitation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II Study
Status: TERMINATED
Conditions: Infant, Premature|Erythropoietin|Brain Injury|Intraventricular Hemorrhage|Periventricular Leukomalacia|Neurodevelopmental Outcomes|Randomized Clinical Trial
Interventions: DRUG: Erythropoietin|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraoperative Intraperitoneal Chemoperfusion to Treat Peritoneal Minimal Residual Disease in Stage III Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer
Interventions: PROCEDURE: Cytoreductive surgery|DRUG: IPEC with Cisplatin (75mg/m²)|DRUG: IPEC with Cisplatin (100mg/m²)|DRUG: Hypertherm IntraPEritoneal Chemotherapy with Cisplatin (75mg/m²)|DRUG: HIPEC with Cisplatin (100mg/m²)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effective High Aerobic Intensity Endurance Training Regimes in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Hyperoxia
Interventions: BEHAVIORAL: 4 times 4 minutes high aerobic intensity one leg cycling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mineralocorticoid Antagonism and Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: COMPLETED
Conditions: ADPKD
Interventions: DRUG: Spironolactone|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation Treating Recurrent Pterygium Trial
Status: COMPLETED
Conditions: Recurrent Pterygium|Micro-Conjunctival Autografting Combined With Amniotic Membrane Transplantation
Interventions: PROCEDURE: Micro-Conjunctival Autograft Combined with Amniotic Membrane Transplantation|PROCEDURE: Conventional Autologous Conjunctival Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Robot-Assisted Intelligent Rehabilitation Treatment in Patients With AUD
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: robot-assisted rehabilitation intelligent treatment|OTHER: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Fear F8ctor Study - Does Fear Induce a Blood Curdling State?
Status: COMPLETED
Conditions: Blood Coagulation Disorder
Interventions: OTHER: Dull movie|OTHER: Scary (horrifying) movie|OTHER: Heart rate measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Proton Pump Inhibitor on Residual Platelet Reactivity After Clopidogrel in Homogenous Genetic Strata
Status: UNKNOWN
Conditions: Coronary Stenting
Interventions: DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Probiotics Administration Before Liver Resection in Liver Disease
Status: COMPLETED
Conditions: Liver Fibrosis|Liver Cirrhosis|Permeability; Increased|Hepatocellular Carcinoma
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Hybrid Effectiveness-implementation Evaluation on Programs Promoting Healthy Aging With Sport Exercise (PHASE Program)
Status: RECRUITING
Conditions: Ageing Well
Interventions: BEHAVIORAL: Gerotechnology enhanced multi-component exercise|BEHAVIORAL: Home-based exercise|BEHAVIORAL: Walking exercise|BEHAVIORAL: Slow sports and exercise|BEHAVIORAL: Football
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Socket Shield Technique Versus Conventional Immediate Implant Placement in Thin Buccofacial Bone
Status: UNKNOWN
Conditions: Crestal Bone Loss
Interventions: DEVICE: Socket shield|PROCEDURE: Conventional immediate implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Therapy of Periodontal Bone Defects
Status: UNKNOWN
Conditions: Periodontal Bone Loss
Interventions: OTHER: OFD with DFDBA|OTHER: OFD with decortication and DFDBA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-serine AudRem: R33 Phase
Status: SUSPENDED
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: DRUG: D-serine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Dose-escalation Study of a Single Administration of Extended-Release Injectable Suspension (ND-340)
Status: SUSPENDED
Conditions: Pain, Postoperative
Interventions: DRUG: ND-340|DRUG: IV-PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ADL5859|DRUG: ADL5747|DRUG: Oxycodone CR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma (PRECAM)
Status: ACTIVE_NOT_RECRUITING
Conditions: MSS Locally Advanced Rectal Adenocarcinoma
Interventions: DRUG: Envafolimab|DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Short-course Radiation|PROCEDURE: TME surgery, total mesorectal excision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pressure Enabled Intrapancreatic Delivery of SD-101 With Checkpoint Blockade for Locally Advanced Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Locally Advanced Pancreatic Adenocarcinoma
Interventions: DRUG: SD-101|BIOLOGICAL: anti-PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-inflammatory Effect of Agaricus Blazei Murill in Inflammatory Bowel Disease (IBD)
Status: COMPLETED
Conditions: Ulcerative Colitis|Crohn's Disease|Inflammatory Bowel Disease
Interventions: DIETARY_SUPPLEMENT: AndoSan|DIETARY_SUPPLEMENT: Sugar Extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bolus vs IVP (Intravenous Push) Diltiazem for Atrial Fibrillation or Flutter
Status: UNKNOWN
Conditions: Atrial Fibrillation|Atrial Flutter|Rapid Ventricular Response
Interventions: DRUG: Diltiazem Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses ofAZD2551
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: AZD2551|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remediation of Working Memory in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Computer Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dimensional Accuracy of Complete Denture With Rapid Prototyping and Conventional Method
Status: UNKNOWN
Conditions: Stability
Interventions: DEVICE: Rapid Prototyping method of fabrication of complete denture|DEVICE: Conventional method of fabrication of complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Efficacy of Long-Term Gantenerumab Administration in Participants With Alzheimer's Disease (AD)
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: Gantenerumab|DRUG: Gantenerumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ACCS100 to Reduce Aflatoxin Exposure in Kenya
Status: COMPLETED
Conditions: Aflatoxicosis
Interventions: DRUG: ACCS100|DRUG: Calcium carbonate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Blood Pressure and Waveform Measurements Comparison Between Invasive Arterial Line and PPG Sensor
Status: COMPLETED
Conditions: Blood Pressure Measurement
Interventions: DEVICE: Arterial catheterization kit|DEVICE: GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor|DEVICE: NIBP Cuff (GE Healthcare)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Non-inferiority Trial to Compare MVA-BN® Smallpox Vaccine to ACAM2000®
Status: COMPLETED
Conditions: 18-42 Year Old Healthy Vaccinia-naïve Subjects
Interventions: BIOLOGICAL: MVA BN®|BIOLOGICAL: ACAM2000®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Manual Physical Therapy and Corticosteroid Injections for Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Orthopaedic manual physical therapy|PROCEDURE: Corticosteroid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Pharmacokinetics of BMS-986165 in a Randomized, Double-Blind, Placebo-Controlled Study in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Autoimmune Diseases
Interventions: DRUG: BMS-986165|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India
Status: COMPLETED
Conditions: Kidney Transplantation|Liver Transplantation
Interventions: DRUG: Advagraf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycemic Response of Bean-and-rice Meals in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Blood Glucose|Type 2 Diabetes Mellitus
Interventions: OTHER: Whole cooked beans with rice meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Rehabilitation Intervention, Supported by Telemedicine, With Standard Rehabilitation After Distal Radius Fracture.
Status: UNKNOWN
Conditions: Distal Radius Fracture
Interventions: DEVICE: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of APN01 (Recombinant Human Angiotensin Converting Enzyme 2)
Status: COMPLETED
Conditions: Pulmonary Diseases|Cardiovascular Diseases|Kidney Diseases|Cancer Diseases
Interventions: BIOLOGICAL: APN01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bifidobacterium Animalis Subsp. Lactis in Prevention of Common Infections in Healthy Children Attending Day Care Centers
Status: COMPLETED
Conditions: Gastrointestinal Tract Infections|Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium animalis subsp. lactis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prophylactic Ketorolac Post Epiretinal Membrane Surgery
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Ketorolac 0.5%|OTHER: Saline drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: EuroPainClinics® Study I (Prospective Trial)
Status: TERMINATED
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: periradicular therapy (PRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Gravity on the Size-mass Illusion
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: parabolic flight|OTHER: mass/weight perception estimation|DEVICE: ESA short-arm human centrifuge (SAHC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Danish Multicenter Scapholunate Ligament Study
Status: RECRUITING
Conditions: Ligament Injury|Wrist Sprain
Interventions: PROCEDURE: Berger|PROCEDURE: 3LT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Béa Applicator and Béa Cervical Cap Safety and Usability Study
Status: UNKNOWN
Conditions: Safety and Usability
Interventions: DEVICE: Béa Applicator and Béa Cervical Cap Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS
Status: UNKNOWN
Conditions: Pneumothorax|Pleurodesis
Interventions: PROCEDURE: VATS pleurodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-Guided Biliary Drainage in Patients With Inoperable Malignant Distal Biliary Obstruction and Failed ERCP: a Prospective Feasibility Multicenter Trial
Status: COMPLETED
Conditions: Malignant Distal Biliary Obstruction
Interventions: OTHER: EUS-guided biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Comparison of Left and Right Sided Approaches to Ablation of the Atrioventricular Junction
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: atrioventricular node ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: aripiprazole (Abilify)|DRUG: ziprasidone (Geodon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Study to Assess Safety, Colonisation and Immunogenicity of Reconstituted Lyophilised Neisseria Lactamica
Status: UNKNOWN
Conditions: Meningitis, Bacterial
Interventions: BIOLOGICAL: Lyophilised Neisseria lactamica
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prevention of Disease Progression in Early Stage Indolent B Cell Malignancies. (SMM)
Status: TERMINATED
Conditions: Monoclonal Gammopathy of Undetermined Significance|Smoldering Multiple Myeloma|Chronic Lymphocytic Leukemia
Interventions: DIETARY_SUPPLEMENT: Omega 3 Fatty Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of OMP-305B83 in Subjects With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: OMP-305B83|DRUG: FOLFIRI|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Endoscopic Submucosal Dissection According to the Sedation Method
Status: COMPLETED
Conditions: Early Gastric Cancer|Gastric Adenoma
Interventions: PROCEDURE: Intermittent midazolam/propofol injection controlled by endoscopist|PROCEDURE: Continuous propofol infusion with opioid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 Tablet in the Treatment of Relapsed / Refractory Mantle Cell Lymphoma (MCL)
Status: UNKNOWN
Conditions: Relapsed / Refractory Mantle Cell Lymphoma (MCL)
Interventions: DRUG: TQ-B3525
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Clinical Study Aimed to Assess the Technical Feasibility of RR2 Wearable Home Care Neuromodulation System
Status: COMPLETED
Conditions: Atrial Fibrillation Recurrence
Interventions: DEVICE: CardiaCareTM RR2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, and Antiviral Activity of Maribavir for the Treatment of Cytomegalovirus (CMV) Infection in Children and Adolescents Who Have Received a Hematopoietic Stem Cell Transplant (HSCT) or a Solid Organ Transplant (SOT)
Status: RECRUITING
Conditions: Cytomegalovirus (CMV)
Interventions: DRUG: Maribavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemiarthroplasty or Internal Fixation for Displaced Femoral Neck Fractures - 5 Years Follow up
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Bipolar hemiarthroplasty|PROCEDURE: Internal fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Assess the Efficacy and Safety of Alpha DaRT224 for the Treatment of Patients With Recurrent Cutaneous Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Recurrent Squamous Cell Carcinoma
Interventions: DEVICE: DaRT seeds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.
Status: COMPLETED
Conditions: Retinal Disease|Bestrophinopathy|Best Vitelliform Macular Dystrophy|Adult Onset Vitelliform Macular Dystrophy|Autosomal Dominant Vitreoretinalchoroidopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Coping Strategies on Interoception and Psychological Resilience in Response to Stress
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Stress management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Video Dance Class and Unsupervised Physical Activity During Covid-19 Pandemic in People With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Parkinson Disease 10
Interventions: OTHER: Video Dance classes|OTHER: Unsupervised physical activities
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring
Status: COMPLETED
Conditions: Acne Scars
Interventions: DEVICE: Venus Viva
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electromyographic Biofeedback on Performance of Vastus Medialis Oblique Muscle in Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Electromyographic Biofeedback|OTHER: Quadriceps Isometric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Combination of LGX818 Plus MEK162 Versus Vemurafenib and LGX818 Monotherapy in BRAF Mutant Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: DRUG: LGX818|DRUG: MEK162|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pro-thrombotic Status in Patients With SARS-Cov-2 Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2
Interventions: OTHER: SARS-Cov-2 infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Alpha-galactosidase Enzyme and Irritable Bowel Syndrome
Status: UNKNOWN
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Alpha-galactosidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Education vs Education Plus Intervention in HIV/HCV Diagnosis (DRIVE 03)
Status: COMPLETED
Conditions: HIV Infection|HCV Coinfection
Interventions: OTHER: HIV/HCV Education plus Testing|OTHER: HIV/HCV Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mineralocorticoid Receptor Antagonists in End Stage Renal Disease
Status: COMPLETED
Conditions: End Stage Renal Disease / Hemodialysis
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Crizotinib as a Potential Targeted Treatment in Cancers With ROS1 Genetic Changes (MATCH-Subprotocol G)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vitamin D2 to Treat Chronic Kidney Disease Mineral and Bone Disorder
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D2|DRUG: 1,25(OH)2 Vit D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT