pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Double-lumen Tubes (DLT) - Health Economic Study
Status: COMPLETED
Conditions: Single Lung Ventilation|Thoracic Surgery|Anesthesia|Cost-effectiveness
Interventions: PROCEDURE: VivaSight double-lumen tube for single-lung ventilation|PROCEDURE: Conventional double-lument tube for single-lung ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Placebo- and Active-Controlled Study of Preladenant in Early Parkinson's Disease (PD) (P05664)
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Preladenant 2 mg tablet|DRUG: Preladenant 5 mg tablet|DRUG: Preladenant 10 mg tablet|DRUG: Rasagiline 1 mg capsule|DRUG: Placebo for Rasagiline 1 mg capsule|DRUG: Placebo for Preladenant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
Status: COMPLETED
Conditions: Cruciate Ligament Rupture
Interventions: PROCEDURE: reconstruction of the ACL and anterolateral ligament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia
Status: WITHDRAWN
Conditions: Hospital-Acquired Bacterial Pneumonia|Ventilator-Associated Bacterial Pneumonia|Hospital-Acquired Pneumonia|Ventilator-Associated Pneumonia
Interventions: DRUG: Meropenem-Vaborbactam|DRUG: Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel for up to a Year in Scalp Psoriasis
Status: COMPLETED
Conditions: Psoriasis of Scalp
Interventions: DRUG: Calcipotriol plus betamethasone dipropionate gel (LEO 80185)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Suitability of ICL for Correction of Refractive Errors Without the Use of Dispersive OVDs
Status: RECRUITING
Conditions: Refractive Errors|Myopia|Myopic Astigmatism|Hypermetropia
Interventions: DEVICE: phakic intraocular lens implantation traditional|DEVICE: phakic intraocular lens implantation reduced OVD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Heart Transplant Rejection|Immune Suppression|Pediatric Heart Transplant|Medication Nonadherence|Health Behavior|Remote Monitoring|Patient Engagement
Interventions: OTHER: DOT intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Pharmacotherapies for Alcoholism (Naltrexone/Ondansetron)
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: ondansetron (Zofran)|DRUG: naltrexone (ReVia)|BEHAVIORAL: Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kunxian Capsule in Treatment Patients With Early Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Treatment
Interventions: DRUG: kunxian capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: BIOLOGICAL: Evolocumab|BIOLOGICAL: Placebo|DRUG: Atorvastatin|DRUG: Ezetimibe|OTHER: Diet Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Line Probe Assay Evaluation Study
Status: COMPLETED
Conditions: Multidrug-Resistant Tuberculosis|Isoniazid Resistant Pulmonary Tuberculosis|Rifampicin Resistant Tuberculosis|Pulmonary Tuberculoses
Interventions: DEVICE: YD REBA MTB-MDR|DEVICE: Hain Genotype MTBDRplus V1|DEVICE: Hain Genotype MTBDRplus V2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment and Natural History Study of Lymphomatoid Granulomatosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphomatoid Granulomatosis|Granulomatosis, Lymphomatoid|Non-Hodgkins Lymphoma|Lymphoproliferative Disorder
Interventions: BIOLOGICAL: Interferon|DRUG: Rituxan and EPOCH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: cytogenetic analysis|GENETIC: proteomic profiling|OTHER: cytology specimen collection procedure|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: breast duct lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 2a Study to Evaluate the Safety/Tolerability and Efficacy of TOP1288 200 mg Rectal Solution Once Daily for 4 Weeks in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: TOP1288|DRUG: Placebo (for TOP1288)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer
Status: RECRUITING
Conditions: Endodontic Disease|Endodontically Treated Teeth
Interventions: OTHER: BioRoot RCS® root canal sealer|OTHER: AH Plus® root canal sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone for Oral Premalignant Lesions
Status: TERMINATED
Conditions: Oral Leukoplakia
Interventions: DRUG: Pioglitazone hydrochloride|OTHER: placebo|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure|Diabetes Mellitus|Arrythmia
Interventions: DRUG: Empagliflozin at a dose of 10 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-2 and Sargramostim After Chemotherapy in Treating Patients With Stage III or Stage IV Melanoma
Status: WITHDRAWN
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: sargramostim|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Using Sperm Bound to the Zona Pellucida of Immature Oocytes for Intracytoplasmic Sperm Injection (ICSI)
Status: COMPLETED
Conditions: Intracytoplasmic Sperm Injection|Infertility, Male
Interventions: OTHER: ZP-binding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT
Status: NOT_YET_RECRUITING
Conditions: Poor Graft Function
Interventions: DRUG: decitabine|BIOLOGICAL: umbilical cord blood|DRUG: Granulocyte-colony stimulating factor|DRUG: Recombinant human thrombopoietin / thrombopoietin receptor agonist|DRUG: Recombinant human erythropoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety & Assess Local and Systemic PK of DS003 Vaginal Tablets Administered to Healthy HIV-negative Women
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: DS003 vaginal tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cervical Adenocarcinoma|Advanced Cervical Adenosquamous Carcinoma|Advanced Cervical Squamous Cell Carcinoma|Advanced Vaginal Adenocarcinoma|Advanced Vaginal Adenosquamous Carcinoma|Advanced Vaginal Squamous Cell Carcinoma|Stage IB2 Cervical Cancer AJCC v6 and v7|Stage II Cervical Cancer AJCC v7|Stage II Vaginal Cancer AJCC v6 and v7|Stage III Vaginal Cancer AJCC v6 and v7|Stage IIIB Cervical Cancer AJCC v6 and v7|Stage IVA Cervical Cancer AJCC v6 and v7|Stage IVA Vaginal Cancer AJCC v6 and v7
Interventions: PROCEDURE: Biospecimen Collection|RADIATION: Brachytherapy|DRUG: Cisplatin|PROCEDURE: Computed Tomography|RADIATION: External Beam Radiation Therapy|OTHER: Fludeoxyglucose F-18|RADIATION: High-Dose Rate Brachytherapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|OTHER: Pharmacological Study|PROCEDURE: Positron Emission Tomography|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintaining Autonomy as we Age. Strategy Training for Age-related Executive Dysfunction.
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Real world strategy approach|BEHAVIORAL: Psychosocial Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Tolerability and Immunogenicity of Nyaditum Resae ® Probiotic Administered to Pediatric Population in Contact With Tuberculosis With or Without Latent Tuberculosis Infection
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Nyaditum resae ® 10e5 of heat-killed Mycobacterium manresensis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CNG Staging Compared With 8th UICC of NPC for Treatment Decision-marking and Selection of Chemotherapy and Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: CNG Chemotherapy|DRUG: NCCN Chemotherapy|RADIATION: CNG Radiation|RADIATION: NCCN Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adenovirus Vascular Endothelial Growth Factor (VEGF) Therapy in Vascular Access - Novel Trinam AGainst Control Evidence
Status: TERMINATED
Conditions: End Stage Renal Disease
Interventions: PROCEDURE: Graft placement surgery plus Trinam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applying Non-invasive Brain Stimulation in Alzheimer's Rehabilitation
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DEVICE: Experimental: Continuous TBS (cTBS)|DEVICE: Intermittent TBS (iTBS)|BEHAVIORAL: Cognitive training (CT).|DEVICE: Sham Stimulation (shamTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Intraocular Pressure (IOP)-Lowering Efficacy of Azopt 1.0% Compared to Timolol 0.5% in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: brinzolamide 1.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed and LBH589 in Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: LBH 589|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Acupuncture Against Postoperative Nausea and Vomit After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Nausea|Postoperative Vomiting|Laparoscopic Cholecystectomy|Acupuncture
Interventions: DEVICE: Acupuncture Needles|DRUG: Antiemetic Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigating the Functional Characteristics of White Matter Fibers During Wakefulness and Sleep Based on SEEG
Status: RECRUITING
Conditions: Refractory Epilepsy|Sleep
Interventions: PROCEDURE: SEEG recording and CCEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rt-fMRI Neurofeedback and AH in Schizophrenia
Status: COMPLETED
Conditions: Audio Visual Hallucinations|Neurofeedback|Schizophrenia|Superior Temporal Gyrus
Interventions: OTHER: rt-fMRI neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Pharmacokinetics (How it Moves Into, Through and Out From the Body) of a New Gadolinium-based Contrast Agent (GBCA) After Injection and How Safe it is in Participants With Normal and Impaired Renal Function
Status: COMPLETED
Conditions: Contrast Enhancement in Magnetic Resonance Imaging
Interventions: DRUG: BAY1747846
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Arts & Health Education to Improve Health, Resilience, and Well-Being
Status: TERMINATED
Conditions: Hypertension|Diabetes|Obesity|COPD|CHF|High Cholesterol|Asthma|Chronic Pain|Multiple Sclerosis|Depression|Anxiety|Heart Diseases|Stroke
Interventions: BEHAVIORAL: HeRe We Arts|BEHAVIORAL: HeRe We Ed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanism Investigation of Selinexor Combined With Lenalidomide and Rituximab in the Treatment of Diffuse Large B-cell Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, Large B-Cell, Diffuse
Interventions: DRUG: Selinexor combined with lenalidomide and rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML
Status: RECRUITING
Conditions: AML|MDS
Interventions: DRUG: Decitabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accommodation Measurements After Bilateral Implantation of an Aspheric Accommodating Lens and Monofocal Aspheric Lenses
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: Crystalens AO|DEVICE: SoftPort LI61AO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strength at Home Couples Program (PTSD-Focused Relationship Enhancement Therapy for Returning Veterans)
Status: COMPLETED
Conditions: Aggression|Post Traumatic Stress Disorders
Interventions: BEHAVIORAL: Strength at Home Couples Group|BEHAVIORAL: Supportive Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Sedative Effect of Dexmedetomidine and Midazolam for TIVA
Status: NOT_YET_RECRUITING
Conditions: Choosing Better Drug Option for Sedation in Pediatric Population Intraoperatively
Interventions: DRUG: Dexmedetomidine injection|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation
Status: ENROLLING_BY_INVITATION
Conditions: Tricuspid Valve Regurgitation, Nonrheumatic|Cardiac Catheterization|Heart Failure, Right Sided|Valve Regurgitation, Tricuspid
Interventions: DEVICE: TriClip TTVr system (Abbott Vascular)|DEVICE: PASCAL TTVr system (Edwards Lifesciences)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Switching COPD Patients From Inhaler Devices to the Omron C28P Nebuliser.
Status: NOT_YET_RECRUITING
Conditions: COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Interventions: DEVICE: Omron C28P nebuliser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Innovative Device for Pain Management by Millimeter Band Radiation : Electronic-Pain Killer.
Status: COMPLETED
Conditions: Osteoarthritis|Peripheral|Pain
Interventions: DEVICE: Conventional pain treatment with daily sessions with innovative medical device, Remedee One, for pain management by Millimeter Band Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells
Status: TERMINATED
Conditions: Stem Cell Transplantation|Bone Marrow Transplantation|Peripheral Blood Stem Cell Transplantation|Allogeneic Transplantation|Genetic Diseases|Thalassemia|Pediatrics|Diamond-Blackfan Anemia|Combined Immune Deficiency|Wiskott-Aldrich Syndrome|Chronic Granulomatous Disease|X-linked Lymphoproliferative Disease|Metabolic Diseases
Interventions: DRUG: Cyclophosphamide Dose Level 1|DRUG: Cyclophosphamide Dose Level 2|DRUG: Cyclophosphamide Dose Level 3|DRUG: Cyclophosphamide Dose Level 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Cognition in Pediatric Epilepsy
Status: RECRUITING
Conditions: Pediatric Epilepsy
Interventions: DIAGNOSTIC_TEST: Neuropsychological evaluation , Evaluation of theory of mind, Evaluation of executive functions, Evaluation of verbal skills
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: 89Zr-DFO-AP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: HCV Viral Hepatitis, Blood Sugar Level and Systolic Blood Pressure in Egypt
Status: COMPLETED
Conditions: Hepatitis C, Acute|Diabetes|Hypertension
Interventions: DIAGNOSTIC_TEST: BIOLINE HCV kits|DIAGNOSTIC_TEST: ACCU-CHEK kits|DIAGNOSTIC_TEST: ErKameter 3000 mercury manometer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating Glycosphingolipid Clearance in Patients Treated With Agalsidase Alfa Who Switch to Agalsidase Beta
Status: COMPLETED
Conditions: Fabry Disease
Interventions: BIOLOGICAL: Agalsidase beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety and Tolerability Study of gpASIT+TM and gpASIT+TM/Immunoregulating Adjuvant to Treat Seasonal Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: gpASIT+TM|BIOLOGICAL: gpAST+TM/adjuvant|BIOLOGICAL: Placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Pilot Study on Lee Silverman Voice Treatment-Loud: a Telerehabilitation Approach
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: LSVT-Loud delivered by telerehabilitation|OTHER: LSVT-Loud in the clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developmental Endothelial Locus-1, Platelet Count, and Soluble P-selectin in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIAGNOSTIC_TEST: Platelet count|DIAGNOSTIC_TEST: Developmental endothelial locus-1 (DEL-1)|DIAGNOSTIC_TEST: soluble P-selectin (sP-sel)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extension Study to Evaluate the Safety and Tolerability of Tezepelumab in Adults and Adolescents With Severe, Uncontrolled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Insufficient Superficial and Perforatring Veins of the Lower Limb Using HIFU
Status: COMPLETED
Conditions: Varicose Veins|Veins Diseases|Varicose Ulcer
Interventions: DEVICE: Sonovein 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess the Pharmacokinetics, Pharmacodynamics, and the Safety and Tolerability of Semaglutide in Healthy Male Japanese and Caucasian Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: semaglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Application of Robotic System in Spinal Surgery
Status: UNKNOWN
Conditions: Robotic Surgical Procedures|Spinal Surgery|Safety
Interventions: DEVICE: TIANJI Robot|DEVICE: Fluoroscopy|DEVICE: Navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Ribavirin 200 Capsules and Rebetol 200 mg Capsules in Females Under Fasting Conditions
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Ribavirin 200 mg Oral Capsule (Geneva Pharmaceutical, U.S.A.)|DRUG: Rebetol 200 mg Oral Capsule (Schering Corporation, U.S.A.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICG for Visualization of the Ureters in DIE
Status: RECRUITING
Conditions: Visualization of Ureters in Gynecological Surgery|Deep Infiltrative Endometriosis|ICG (Indocyanine Green)|Near Infrared Imaging|Laparoscopy
Interventions: DRUG: Ureteral injection of Indocyanine Green Powder (diluted)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PRISM Race and Communication Pilot RCT
Status: RECRUITING
Conditions: Discrimination, Racial|Communication|Chronic Illness|Bias, Racial
Interventions: BEHAVIORAL: Promoting Resilience in Stress Management (PRISM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of r-hLH (Luveris) in Donors Previously Treated With r-hFSH (Gonal F)
Status: COMPLETED
Conditions: Outcome During r-hFSH Stimulation|Outcome During r-hFSH and r-hLH Stimulation
Interventions: DRUG: r-hFSH|DRUG: r-hFSH and r-hLH
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Pericapsular Nerve Group (PENG) Block and Interscalene Brachial Plexus Block for Postoperative Analgesia Following Shoulder Arthroscopy
Status: RECRUITING
Conditions: Pericapsular Nerve Block|Interscalene Brachial Plexus Block|Shoulder Arthroscopy
Interventions: OTHER: Control Group (Interscalene brachial plexus block)|PROCEDURE: Pericapsular nerve group (PENG) block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What is the Optimal Stiffness and Height of a Running-specific Prosthesis?
Status: COMPLETED
Conditions: Amputation, Traumatic|Traumatic Amputation of Lower Extremity|Wounds and Injuries
Interventions: DEVICE: Otto Bock prosthesis|DEVICE: Ossur prosthesis|DEVICE: Freedom Innovations prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Relationship of Cervical Region Tension With Vagal Function
Status: COMPLETED
Conditions: Gastrointestinal Diseases|Autonomic Nervous System Disease
Interventions: OTHER: VAGUS-NDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Evaluation of Preoperative Nasoendoscopy to Predict Difficult Intubation
Status: UNKNOWN
Conditions: Difficult or Failed Intubation|Obesity, Morbid
Interventions: PROCEDURE: Awake Airway Nasoendoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dexmedetomidine Reduces Sevoflurane MAC-BAR During Pneumoperitoneum
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Dexmedetomidine low-dose|DRUG: normal Saline|DRUG: Dexmedetomidine high-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Status: COMPLETED
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Adductor Canal Block for Total Knee Replacement
Status: COMPLETED
Conditions: Complications; Arthroplasty|Knee Injuries
Interventions: DRUG: Bupivacaine|DRUG: Preservative free normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Fiber flowable (SFRC) support below hybrid nanoceramic endocrowns|PROCEDURE: all ceramic Endocrowns (emax)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of FeNO for Predicting Response to ICS in Subjects With Non-specific Respiratory Symptoms
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Qvar (100 mcg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Multi-Site Phase 2b Clinical Study
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: NVXT topical|DRUG: Placebo (Vehicle) Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Polypectomy of Non-pedunculated Colorectal Adenomas
Status: UNKNOWN
Conditions: Colorectal Polyp
Interventions: PROCEDURE: Cold snare polypectomy|PROCEDURE: Hot snare polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Voice Therapy and Antireflex Therapy in LPR
Status: WITHDRAWN
Conditions: Laryngopharyngeal Reflux
Interventions: DRUG: Omeprazole, Lansoprazole, Esomeprazole, Rantidine|BEHAVIORAL: Voice therapy|OTHER: Combination of anti-reflux medication and voice therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyethylene Body Bags as an Alternative to Radiant Heat Lamp During the Neonatal Adaptation in Infants Older Than 29 Weeks
Status: COMPLETED
Conditions: Neonatal Adaptation
Interventions: DEVICE: polyethylene plastic bag|DEVICE: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia
Status: COMPLETED
Conditions: Acquired Hyperinsulinemic Hypoglycemia
Interventions: DRUG: Avexitide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Donor Stem Cell Transplant, Tacrolimus, Mycophenolate Mofetil, and Cyclophosphamide in Treating Patients With Hematologic Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myelodysplastic Syndromes
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Manipulation for Female Interstitial Cystitis Patients With Sacroiliac Joint Dysfunction
Status: UNKNOWN
Conditions: Interstitial Cystitis|Sacroiliac Joint Somatic Dysfunction
Interventions: PROCEDURE: Osteopathic Manipulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Short and Long Intravenous Infusion Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-962212 in Healthy Subjects
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: BMS-962212|DRUG: Aspirin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Mirror Therapy and Phantom Limb Pain
Status: UNKNOWN
Conditions: Phantom Limb Pain|Phantom Pain|Phantom Sensation|Pseudomelia
Interventions: DEVICE: Sham (Comparator) Plasma Ball|DEVICE: Mirror
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of a School-based Intervention to Improve the Wellbeing of Children Aged 8-11 Years.
Status: RECRUITING
Conditions: Well-Being, Psychological|Child, Only
Interventions: BEHAVIORAL: A Lust for Life|BEHAVIORAL: Waiting List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of OVV-01 Injection in Combination With IBR900 Cell Injection in Patients With Advanced Malignant Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumor|Relapsed/Refractory Lymphoma
Interventions: BIOLOGICAL: OVV-01 Injection+IBR900 Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of the Safety and Surrogate Marker Efficacy of Butyldeoxynojirimycin (SC-48334) and AZT in Symptomatic HIV-1 Infected Patients With 200 - 500 CD4+ Cells/mm3. (NOTE: Asymptomatic HIV-1 Infected Patients Also Eligible)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Butyldeoxynojirimycin|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vitrectomy With Internal Limiting Membrane Peeling for Myopic Traction Maculopathy
Status: COMPLETED
Conditions: Myopic Traction Maculopathy|Pars Plana Vitrectomy|Internal Limiting Membrane Peeling
Interventions: PROCEDURE: Pars Plana Vitrectomy with Internal Limiting Membrane peel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
Status: RECRUITING
Conditions: Revision Spine Surgery|Fusion of Spine|Cervical Fusion|Lumbar Fusion
Interventions: DRUG: Ketamine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block Versus Thoracic Epidural Block for Chest Trauma
Status: COMPLETED
Conditions: Chest Trauma
Interventions: PROCEDURE: ESP block|PROCEDURE: TEA|DEVICE: Catheter insertion|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Dose Escalation Study of AV-203, an ERBB3 Inhibitory Antibody, in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: BIOLOGICAL: AV-203
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Ultrasound-guided Multiple-injection Costotransverse Block for Mastectomy and Primary Reconstructive Surgery.
Status: COMPLETED
Conditions: Breast Cancer|Ductal Carcinoma in Situ
Interventions: DRUG: Ropivacaine injection|DRUG: Saline 0.9%|DRUG: Sufentanil and PONV prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Auricular Vagus Nerve Stimulation in Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries|Spinal Cord Diseases|Nervous System Diseases|Trauma, Nervous System|Movement Disorders|Central Nervous System Diseases
Interventions: DEVICE: active taVNS|DEVICE: sham taVNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy
Status: WITHDRAWN
Conditions: Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Tongue Cancer
Interventions: DRUG: everolimus|DRUG: erlotinib hydrochloride|PROCEDURE: biopsy|OTHER: laboratory biomarker analysis|OTHER: immunohistochemistry staining method|GENETIC: polyacrylamide gel electrophoresis|OTHER: pharmacological study|RADIATION: external beam radiation therapy|GENETIC: microarray analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Aphasia - Improved by Intensive Training and Electrical Brain Stimulation
Status: UNKNOWN
Conditions: Post-Stroke Chronic Aphasia|Anomia (Word-retrieval Impairment)
Interventions: BEHAVIORAL: Intensive language therapy|BEHAVIORAL: Intensive language therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Hyponatremia in PEG-SD Compared to PEG-ELS
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: PEG-SD|DRUG: PEG-ELS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: The Influence of Personal Care Products on the Skin Microbiome
Status: COMPLETED
Conditions: Microbiome
Interventions: OTHER: Burt's Bees Serum|OTHER: Burt's Bees Serum with Biulin|OTHER: Burt's Bees Serum with Bonicell|OTHER: Burt's Bees Serum with Berenew Complex|OTHER: Burt's Bees Serum with Ecoskin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Single and Multiple Dose Study of Canagliflozin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Canagliflozin 100 mg|DRUG: Canagliflozin 50 mg|DRUG: Canagliflozin 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD of Intravenous Ferric Carboxymaltose in Infants With Iron Deficiency Anemia
Status: WITHDRAWN
Conditions: Iron Deficiency, Anaemia
Interventions: DRUG: Ferric carboxymaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Durvalumab Plus Tremelimumab With Concurrent Radiotherapy for Localized Muscle Invasive Bladder Cancer Treated With a Selective Bladder Preservation Approach
Status: UNKNOWN
Conditions: Invasive Bladder Cancer
Interventions: DRUG: Durvalumab|DRUG: Tremelimumab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Placebo Group|DIETARY_SUPPLEMENT: Whey Protein + Placebo|DIETARY_SUPPLEMENT: Omega 3 + Placebo|DIETARY_SUPPLEMENT: Omega 3 + Whey Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Anugel With Gelatine Sponges for Pain Management After Hemoroidectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: COMBINATION_PRODUCT: Anugel, Hydrogel sponge|COMBINATION_PRODUCT: Gelatine Sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Let's Know!2: Language-focused Intervention for Children at Risk of Comprehension Difficulties
Status: RECRUITING
Conditions: Language Disorders in Children
Interventions: BEHAVIORAL: Let's Know! small-group or TierL 2 Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain
Status: RECRUITING
Conditions: Cardiac Surgery|Sternotomy|Acute Pain
Interventions: DRUG: Ropivacaine 0.2% Injectable Solution Bolus|OTHER: Normal Saline Infusion|DRUG: Ropivacaine 0.2% Injectable Solution Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label, Long-Term Study With AL-4943A Ophthalmic Solution, 0.2% in Patients With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine Hydrochloride Ophthalmic Solution, 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventive Effect of Acetyl-L-carnitine on Oxaliplatin-induced Peripheral Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Acetylcarnitine|Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Acetyl-L-carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Of A Novel Hand-held Retractor-Assisted Transforaminal Lumbar Interbody Fusion By The Wiltse Approach And Posterior TLIF
Status: COMPLETED
Conditions: Lumbar Stenosis|Spondylolisthesis
Interventions: PROCEDURE: new hand-held retractor systems-assisted WiltseTLIF surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Construction and Validation of a Risk Prediction Model for Secondary Vertebral Fracture in Patients With Osteoporotic Vertebral Compression Fractures After Percutaneous Vertebroplasty
Status: RECRUITING
Conditions: Osteoporotic Vertebral Fracture|Prediction Model
Interventions: OTHER: No interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Buccal Fat Pad Derived Stem Cells in Maxillary Sinus Augmentation
Status: UNKNOWN
Conditions: Alveolar Bone Loss
Interventions: PROCEDURE: BFPSCs+ DFDBA+ PRF|PROCEDURE: DFDBA + PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Effects of NPSP795 on the Calcium-sensing Receptor in Subjects With Autosomal Dominant Hypocalcemia as Measured by PTH Levels and Blood Calcium Concentrations
Status: COMPLETED
Conditions: Autosomal Dominant Hypocalcemia (ADH)
Interventions: DRUG: NPSP795
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memory and Antioxidants in Vascular Impairment Trial
Status: COMPLETED
Conditions: Vascular Cognitive Impairment no Dementia
Interventions: DRUG: N Acetylcysteine|OTHER: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of the SurVeil™ Drug-Coated Balloon (AVess FIH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemodialysis Access Failure
Interventions: DEVICE: SurVeil Drug Coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2B Extension Study of Ataluren (PTC124) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy|Becker Muscular Dystrophy
Interventions: DRUG: Ataluren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS as a Treatment of Neuropathic Pain Secondary to Malignancy
Status: COMPLETED
Conditions: Malignancy
Interventions: PROCEDURE: 20 Hz, 10 s, 10 trains with inter-train interval 30 s 2000 pulses , intensity 80% over hand area daily for 10 consecutive days (5 days/week).|PROCEDURE: sham rTMS (same parameters but with coil elevated and angled away from the head)every day for ten consecutive days (5 days/week).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Larotaxel/Docetaxel, +/- Trastuzumab, After Anthracycline-cyclophosphamide in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: larotaxel (XRP9881)|DRUG: docetaxel|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Relevance and Reliability of Gastrointestinal Temperature Measurements From a New Device (E-celsius)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: E-Celsius thermometer|DEVICE: Rectal thermometer|DEVICE: Esophageal thermometer|DEVICE: Vital sense capsule thermometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors
Status: COMPLETED
Conditions: Muscle Pain|Joint Pain
Interventions: DRUG: Vitamin D3|DRUG: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: oral topotecan (SK&F-104864); lapatinib (GW572016)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Estradiol+Drospirenone Versus Estradiol+MPA on Endothelial Function
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Estradiol+MPA|DRUG: Estradiol+Drospirenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION