pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of PRP, PPP, & BMAC on Functional Outcomes Following Hip Arthroscopy for Acetabular Labral Pathologies
Status: RECRUITING
Conditions: Acetabular Labrum Tear|Femoro Acetabular Impingement|Chondral Defect|Bone Marrow Aspirate Concentrate
Interventions: BIOLOGICAL: Bone marrow aspirate concentrate (BMAC)|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Strain-counterstrain and Muscle Energy Technique in Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Somatic Dysfunction
Interventions: PROCEDURE: Strain-Counterstrain|PROCEDURE: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Parallel-Group, 24-Week, Chronic-Dosing, Multi-Center Study to Assess the Efficacy and Safety of PT010, PT003, and PT009 Compared With Symbicort® Turbuhaler® (Kronos)
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: BGF MDI 320/14.4/9.6 μg|DRUG: GFF MDI (PT003) 14.4/9.6 μg|DRUG: BFF MDI (PT009) 320/9.6 μg|DRUG: Symbicort® Turbuhaler® (TBH) Inhalation Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Subacromial Infiltrations
Status: COMPLETED
Conditions: Subacromial Bursitis|Subacromial Impingement Syndrome|Rotator Cuff Impingement Syndrome
Interventions: PROCEDURE: Subacromial high volume infiltration|PROCEDURE: Subacromial conventional infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: American Trial Using Tranexamic Acid in Thrombocytopenia
Status: COMPLETED
Conditions: Thrombocytopenia
Interventions: DRUG: Tranexamic Acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of External Eye Surgery
Status: COMPLETED
Conditions: Pterygium|Ocular Surface Cicatrizing Diseases
Interventions: DEVICE: Tisseel fibrin adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Basic Body Awareness Therapy on Pain, Sleep, Disability and Quality of Life in Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Conventional Therapy Program|OTHER: Basic Body Awareness Therapy Group Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3819253 (LY-CoV555) and LY3832479 (LY-CoV016) in Participants With Mild to Moderate COVID-19 Illness
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: LY3819253|DRUG: LY3832479|DRUG: LY3853113|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Approval Study of the Ovation™/Ovation Prime™ Abdominal Stent Graft System
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: Ovation™/Ovation Prime™ Abdominal Stent Graft System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interleukin-6 Receptor Inhibition for Symptomatic Intracranial Atherosclerosis
Status: NOT_YET_RECRUITING
Conditions: Brain Diseases|Ischemic Stroke|Ischemia|Stroke|Cerebral Infarction|Atherosclerosis of Artery|Atheroscleroses, Intracranial
Interventions: DRUG: Tocilizumab|DRUG: NaCl 0.9% 100ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Lamotrigine.
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Eslicarbazepine acetate|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of Ferric Maltol Oral Suspension vs. Ferrous Sulfate Oral Liquid in Children and Adolescents Aged 2 to 17 Years With Iron-deficiency Anaemia, With a Single Arm Study in Infants Aged 1 Month to Less Than 2 Years
Status: RECRUITING
Conditions: Anemia|Iron-deficiency
Interventions: DRUG: Ferric Maltol|DRUG: Ferrous sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mecapegfilgrastim for the Prevention of Dalpiciclib -Induced Neutropenia in Advanced Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Mecapegfilgrastim|DRUG: dalpiciclib|DRUG: exemestane, fulvestrant, letrozole, tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hypertension Prevention Trial (HPT) Feasibility Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Obesity|Vascular Diseases
Interventions: BEHAVIORAL: diet, sodium-restricted|BEHAVIORAL: diet, reducing|DRUG: potassium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: floxuridine|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: melphalan|PROCEDURE: hyperthermia treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Medical Expulsive Therapy of Single Distal Ureteral Stones
Status: COMPLETED
Conditions: Ureteral Calculi
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TLR9 Agonist SD-101, Anti-OX40 Antibody BMS 986178, and Radiation Therapy in Treating Patients With Low-Grade B-Cell Non-Hodgkin Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Grade 1 Follicular Lymphoma|Grade 2 Follicular Lymphoma|Grade 3a Follicular Lymphoma|Lymphoplasmacytic Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Anti-OX40 Antibody BMS 986178|OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy|DRUG: TLR9 Agonist SD-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Rifalazil for the Treatment of Chlamydia Trachomatis Infection in Women
Status: COMPLETED
Conditions: Chlamydia Trachomatis Infection
Interventions: DRUG: Rifalazil 25 milligram|DRUG: Azithromycin 1 gram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Personalized Actionable Connected Extensible (PACE) Interventions Among Patients With Chronic Kidney Disease
Status: RECRUITING
Conditions: CKD - Chronic Kidney Disease
Interventions: BEHAVIORAL: PACE intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties
Status: COMPLETED
Conditions: Papulopustular Rosacea
Interventions: DRUG: Encapsulated Benzoyl Peroxide Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Platelet- and Extracellular Vesicle-rich Plasma in Chronic Postsurgical Temporal Bone Inflammations
Status: COMPLETED
Conditions: Otitis Media Chronic|Temporal Bone
Interventions: DRUG: Platelet- and extracellular vesicle-rich plasma|DRUG: Standard conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laughter Therapy Application in Hemodialysis Patients
Status: COMPLETED
Conditions: Comfort|Acceptance Processes|Hemolysis|Laughter Therapy|Treatment Adherence|Patients
Interventions: BEHAVIORAL: Laughter Therapy|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease, Early Onset|Atypical Alzheimer's Disease|Logopenic Progressive Aphasia
Interventions: DEVICE: Active HD-tDCS|DEVICE: Sham|OTHER: Word List Learning Intervention (WordLLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulating Cortical Dynamics of Dual-task Standing in MCI
Status: RECRUITING
Conditions: Aging|Mild Cognitive Impairment
Interventions: OTHER: real tACS|OTHER: sham tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: TDF|DRUG: Peg-IFN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of a Periodontal Endoscope in Nonsurgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontitis, Adult
Interventions: DEVICE: Use of Periodontal Endoscope (Perioscopy®) to enhance visualization while performing teeth deep cleaning|DEVICE: Use of traditional loupes to enhance magnification to enhance visualization while performing teeth deep cleaning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fluorescence Imaging of IBD and RA Using Adalimumab-800CW
Status: NOT_YET_RECRUITING
Conditions: IBD|Rheumatoid Arthritis
Interventions: DRUG: Adalimumab-800CW|DEVICE: Fluorescence Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Newly Diagnosed High Grade Glioma Treated With Concurrent Radiation Therapy, Temozolomide and BMX-001
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma|Astrocytoma, Grade III|Glioblastoma
Interventions: DRUG: BMX-001|RADIATION: Radiation Therapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease
Status: UNKNOWN
Conditions: Cardiac TTR Amyloidosis
Interventions: DIAGNOSTIC_TEST: Tc99m-labeled pyrophosphate scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Yunzhi Essence to Improve the Quality of Life of Patients With Advanced Stage of Cancer
Status: NOT_YET_RECRUITING
Conditions: Cancer|Palliative Care
Interventions: DRUG: Yunzhi Essence|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immune Tolerance Induction Study
Status: TERMINATED
Conditions: Pompe Disease|Glycogen Storage Disease Type II (GSD-II)|Glycogenesis 2 Acid Maltase Deficiency
Interventions: BIOLOGICAL: Myozyme® (alglucosidase alfa)|BIOLOGICAL: Myozyme® (alglucosidase alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit of the Treatment With Testosterone in Chronic Heart Failure Testosterone Deficiency Subjects
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Testosterone undecanoate|DRUG: Saline isotonic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Poliomyelitis|Hepatitis B|Haemophilus Influenzae Type b Infection
Interventions: BIOLOGICAL: DTP-HepB-IPV-Hib vaccine|BIOLOGICAL: DTP-HepB-Hib vaccine & IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Oat Products in the Treatment of Coeliac Disease in Children
Status: UNKNOWN
Conditions: Clinical and Nutritional Safety.
Interventions: OTHER: Gluten-free products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot of Mindfulness Oriented Recovery Enhancement in MethadoneTreatment
Status: COMPLETED
Conditions: Opioid Use|Chronic Pain
Interventions: BEHAVIORAL: Mindfulness Oriented Recovery Enhancement|BEHAVIORAL: Methadone program behavioral treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Versus Chemotherapy for Endometrial Carcinoma (ENGOT-en9 / MK-7902-001)
Status: ACTIVE_NOT_RECRUITING
Conditions: Endometrial Neoplasms
Interventions: DRUG: Lenvatinib|BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Relative Bioavailability of Moexipril HCl/Hydrochlorothiazide in Healthy Adult Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moexipril HCl/ Hydrochlorothiazide 15mg/ 25mg Tablet, Paddock Laboratories, Inc.|DRUG: Uniretic® 15mg/25mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The LANCET Trial: A Trial of Long-acting Insulin Injection to Reduce C-reactive Protein in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Insulin glargine injection|DRUG: metformin|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
Status: RECRUITING
Conditions: Genu Varum|Genu Valgus|Flat Feet|Cavus Foot|Scoliosis Idiopathic|Varus; Talipes|Valgus, Talipes|Laxity of Ligament|Hyperlordosis|Hyperkyphosis|Angular Limb Deformity
Interventions: DIAGNOSTIC_TEST: Clinical tests and motor control evaluation using Inertial Measurement Units
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin K2 Supplementation to Activate Matrix Gla Protein (MGP) as Endogenous Inhibitor of Vascular Calcification in Hemodialysis Patients
Status: COMPLETED
Conditions: CKD 5D, Hemodialysis
Interventions: DIETARY_SUPPLEMENT: daily supplementation of MK-7 over 6 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Manville Moves: an Exercise Intervention for Behavioral Regulation Among Children With Behavioral Health Challenges
Status: COMPLETED
Conditions: Autistic Disorder|Attention Deficit and Disruptive Behavior Disorders|Anxiety Disorders|Mood Disorders|Conduct Disorder|Oppositional Defiant Disorder
Interventions: BEHAVIORAL: Aerobic Exergaming PE Curriculum|BEHAVIORAL: Standard PE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-exposure Simple Suturing EFTR (NESS-EFTR) With Laparoscopic Sentinel Lymph Node Navigation for EGC (Senorita3-phase 2)
Status: UNKNOWN
Conditions: Early Gastric Cancer
Interventions: PROCEDURE: NESS-EFTR with sentinel lymph node navigation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Poziotinib|DRUG: T-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of OMT on Functional Outcomes and Anti-inflammatory Biomarkers in Mild to Moderate Traumatic Brain Injury
Status: COMPLETED
Conditions: Vestibular Disorder|Headache|Traumatic Brain Injury
Interventions: OTHER: Osteopathic Manipulative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics Profile of DWCZP Tablet 100mg and Clozaril® Tablet 100mg
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: DWCZP|DRUG: Clozaril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FIrst Line Treatment of Metastatic Pancreatic Cancer: Sequential Nab-paclitaxel + Gemcitabine/FOLFIRI.3 VS Nab-paclitaxel + Gemcitabine
Status: COMPLETED
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: FOLFIRI.3|DRUG: nab-paclitaxel+ gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0337, Gemcitabine After Surgery in Treating Patients With Newly Diagnosed or Recurrent Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: gemcitabine hydrochloride|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maraviroc Versus Etravirine In Combination With Antiretroviral Therapy In Drug Experienced HIV And Hepatitis Co-Infected Patients
Status: WITHDRAWN
Conditions: Hepatitis B|Human Immunodeficiency Virus|Hepatitis C, Chronic
Interventions: DRUG: maraviroc|DRUG: etravirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyadic Yoga Intervention for Patient With Head and Neck Cancer Undergoing Radiotherapy and Their Family Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Neoplasms of Lip Oral Cavity and Pharynx|Head and Neck Cancer
Interventions: BEHAVIORAL: Yoga|BEHAVIORAL: Yoga Questionnaire|BEHAVIORAL: Symptom Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CASUS: Validation for Detection of Precursor Lesions
Status: COMPLETED
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia|Human Papilloma Virus|HPV-Related Cervical Carcinoma|Urine
Interventions: DEVICE: Colli-Pee Small Volumes (10 mL) device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tridimensional Pelvic Floor Ultrasound and Quality of Life Scores Questionnaires in Nulliparous or Parous Women
Status: COMPLETED
Conditions: Urinary Incontinence|Anal Incontinence|Sexual Dysfunction|Self Esteem|Delivery
Interventions: DIAGNOSTIC_TEST: 3D pelvic ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety in Kidney Transplant Recipients When Changed From Cyclosporine to Tacrolimus Prolonged-release Capsule or Tacrolimus Capsule
Status: TERMINATED
Conditions: Kidney Transplant Recipients
Interventions: DRUG: Advagraf|DRUG: Prograf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Swelling Management After Knee Replacement
Status: RECRUITING
Conditions: Arthroplasties, Knee Replacement
Interventions: OTHER: Inelastic adjustable compression garment (INCOM)|OTHER: Elastic compression garment (CONTROL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Ongoing Pregnancy Rate for Vitrification of Day-4 Morula With Day-5 Blast
Status: TERMINATED
Conditions: Infertility
Interventions: OTHER: Morula Vitrification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Status: RECRUITING
Conditions: Infertility, Female
Interventions: DRUG: letrozole plus metformin|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The VIDYA Study-designed to Determine if Patients With a History of Basal Cell Carcinoma Are More Inclined to Return for Follow-up if Their Risk of a Subsequent Basal Cell Carcinoma is Quantitated.
Status: WITHDRAWN
Conditions: Basal Cell Carcinoma
Interventions: OTHER: individualized risk assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Lumify™ Eyedrops on Eyelid Position
Status: COMPLETED
Conditions: Eyelid Droop
Interventions: DRUG: Brimonidine tartrate ophthalmic solution 0.025%|OTHER: Sterile balanced saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery Compared to Observation in Treating Patients With Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain
Interventions: RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Presence of a Therapy Dog Reduces Pain and Anxiety During Pediatric Elbow Pin Removal
Status: NOT_YET_RECRUITING
Conditions: Elbow Injury
Interventions: BEHAVIORAL: No Dog Present|BEHAVIORAL: Dog is Present
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II Study of CAMPATH in Patients With Relapsing or Refractory Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide, methotrexate, fluorouracil, PEG-filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Versus Corticosteroid Injections for Sacroiliac Joint Pain
Status: NOT_YET_RECRUITING
Conditions: Sacro-iliac Joint Pain
Interventions: DRUG: Methylprednisolone Injection|DRUG: Ketorolac Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Study of New Compounds With Potential Use in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: URB597|DRUG: intranasal Insulin|DRUG: Cannabidiol CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted Laparoscopic Partial Nephrectomy Via the Extraperitoneal Approach in the Prone Position Versus the Lateral Position
Status: RECRUITING
Conditions: Renal Tumor|Prone Position|Robotic Assisted Partial Nephrectomy
Interventions: PROCEDURE: Robot-assisted laparoscopic partial nephrectomy via extraperitoneal approach in the prone position|PROCEDURE: Robot-assisted laparoscopic partial nephrectomy via extraperitoneal approach in the lateral position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor, Daratumumab, Carfilzomib and Dexamethasone for the Treatment of High-Risk, Recurrent or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Carfilzomib|BIOLOGICAL: Daratumumab|DRUG: Dexamethasone|OTHER: Quality-of-Life Assessment|DRUG: Selinexor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Prior Walking on Postprandial Metabolism and Endothelial Function.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Cardiovascular Diseases|Endothelial Dysfunction|Insulin Resistance|Oxidative Stress
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reliability and Performance Analysis of the Use of Tissue Flossing for Blood Flow Restriction.
Status: NOT_YET_RECRUITING
Conditions: Hypertrophy|Muscle Strength
Interventions: DEVICE: Tissue Flossing|DEVICE: Blood Flow Restriction Cuff|OTHER: Training Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, and Pharmacodynamic Study of ISIS CRP Rx in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ISIS CRP Rx or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Terbinafine Hydrochloride Tablets, 250 mg of Dr. Reddy's Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Terbinafine Hydrochloride Tablets, 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis
Status: RECRUITING
Conditions: Primary Myelofibrosis|Secondary Myelofibrosis
Interventions: DRUG: Cyclophosphamide|DRUG: JAK Inhibitor|DRUG: Fludarabine|BIOLOGICAL: Recombinant Granulocyte Colony-Stimulating Factor|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Biospecimen Collection|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-hormonal Medical Device for Treatment of Vulvovaginal Atrophy (VVA) in Post-Menopausal Women
Status: COMPLETED
Conditions: Vulvovaginal Atrophy
Interventions: DEVICE: Non-hormonal vaginal device therapy|DEVICE: Sham vaginal device therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Myofascial Release Technique on Upper Limb Functions in Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Myofascial Release Technique|OTHER: Myofascial Release Technique along with segmental vibrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Efficacy of µSmin® Plus
Status: COMPLETED
Conditions: Chronic Venous Disease
Interventions: DIETARY_SUPPLEMENT: µSmin® Plus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enzalutamide in Metastatic or Advanced Non-resectable Granulosa Cell Ovarian Tumors: GREKO III Study
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Enzalutamide 40 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Beta Thalassemia Treatment: Findings From The Extension Period
Status: ACTIVE_NOT_RECRUITING
Conditions: Fetal Hemoglobin|Beta-Thalassemia|Hemoglobinopathies
Interventions: DRUG: thalidomide and hydroxyurea|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentrate of Autologous Rich Plasma in Growth Factors in the Treatment of the Thin Endometrium
Status: COMPLETED
Conditions: Infertility|Infertility, Female
Interventions: DRUG: Plasma rich in growth factors (PRGF-Endoret)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK Study of Diet Effect of Trazodone Hydrochloride Prolonged-Released Tablets in Healthy Chinese
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Trazodone Hydrochloride prolonged-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study in Patients With Epidermal Growth Factor Receptor (EGFR) + Advanced Stage Ovarian, Primary Peritoneal and Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Neoplasms|Fallopian Tube Neoplasms
Interventions: BIOLOGICAL: Cetuximab:|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the AP203 Plant Extract Mixture in Adult Patients With Increased Incidence of Viral and/or Bacterial Upper Respiratory Tract Infections
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection Bacterial
Interventions: DIETARY_SUPPLEMENT: AP203 mixture (RESCOVIN®)|DIETARY_SUPPLEMENT: AP203 mixture (RESCOVIN®)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Shedding, Immunogenicity and Safety of Quadrivalent Live Intranasal Influenza Vaccine (QLAIV) in HIV-infected Children and Young Adults
Status: COMPLETED
Conditions: Human Immunodeficiency Virus (HIV)
Interventions: BIOLOGICAL: Quadrivalent Live Attenuated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ketamine in Robot-assisted Thyroidectomy
Status: UNKNOWN
Conditions: Thyroid|Acute Pain|Chronic Pain
Interventions: DRUG: Ketamine infusion|DRUG: NS infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Urine CXCL10 Monitoring Trial in Kidney Transplant
Status: RECRUITING
Conditions: Kidney Transplant; Complications|Rejection of Renal Transplant
Interventions: PROCEDURE: Kidney transplant biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Blood Flow Restriction for Optimizing Balance in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson's Disease and Parkinsonism
Interventions: OTHER: Blood flow restriction training|OTHER: Instability Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Experimental and Commercial Air-Activated, Adhesive Backed Heat Patches
Status: COMPLETED
Conditions: Effects of Heat|Tolerability|Adhesiveness|Dermal Irritation
Interventions: DEVICE: Thermal Adhesive Patch|DEVICE: Marketed Thermal Adhesive Patch|DEVICE: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Eosinophilic Esophagitis Treatment: Montelukast vs Fluticasone
Status: WITHDRAWN
Conditions: Eosinophilic Esophagitis|Dysphagia
Interventions: DRUG: Montelukast|DRUG: Fluticasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fulvestrant and Palbociclib With or Without Copanlisib in Treating Patients With Hormone Receptor Positive, HER2 Negative, Stage IV Breast Cancer
Status: WITHDRAWN
Conditions: Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Positive|Stage IV Breast Cancer AJCC v6 and v7
Interventions: DRUG: Copanlisib|DRUG: Fulvestrant|OTHER: Laboratory Biomarker Analysis|DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of ALS-L1023 Administered in Combination With Ranibizumab in Patients With Wet-AMD
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: ALS-L1023|DRUG: Ranibizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phenotype Identification Based on Multimodal MRI Analysis of Patients With Bronchial Obstructive Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma Copd
Interventions: PROCEDURE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Of Web-based Breastfeeding Education
Status: ENROLLING_BY_INVITATION
Conditions: Volunteering to Participate in the Study
Interventions: OTHER: THE GROUP THAT WILL TAKE WEB-BASED BREASTFEEDING EDUCATION IN PREGNANCY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Vildagliptin and Metformin Tablets 50/1000 mg Relative to GALVUS MET (50mg/1000 mg) Tablets
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Vildagliptin and Metformin-Test product|DRUG: Vildagliptin and Metformin-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mechanical Control of Plaque in Patients With Cerebral Palsy: A Randomized Clinical Trial
Status: COMPLETED
Conditions: Cerebral Palsy;|Dental Plaque
Interventions: DEVICE: manual brushing|DEVICE: electric toothbrush linked|DEVICE: off electric toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Baricitinib (LY3009104) in Combination With Topical Corticosteroids in Adults With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Baricitinib|DRUG: Topical corticosteroid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Grass Pollen Allergoid in the Treatment of Allergic Rhinoconjunctivitis
Status: COMPLETED
Conditions: Grass Pollen Allergy
Interventions: BIOLOGICAL: Allergovit 6-grasses|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structural Fat Grafting for Craniofacial Trauma: Repeat Fat Grafting Injection-5 Subject Cohort
Status: COMPLETED
Conditions: Facial Injuries|Adipose Tissue
Interventions: PROCEDURE: Repeat Fat grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simplified Severe Sepsis Protocol-2 (SSSP-2) in Zambia
Status: COMPLETED
Conditions: Sepsis|Severe Sepsis|Tuberculosis
Interventions: OTHER: Simplified severe sepsis protocol|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Milking Versus Delayed Cord Clamping in Full Term Neonates
Status: COMPLETED
Conditions: Neonatal Anemia
Interventions: PROCEDURE: cord milking|PROCEDURE: delayed cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome|Acute Myeloid Leukemia/Transient Myeloproliferative Disorder|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Childhood Acute Myeloid Leukemia in Remission|Childhood Myelodysplastic Syndromes|de Novo Myelodysplastic Syndromes|Myelodysplastic Syndrome With Isolated Del(5q)|Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable|Previously Treated Myelodysplastic Syndromes|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes
Interventions: RADIATION: total-body irradiation|PROCEDURE: allogeneic hematopoietic stem cell transplantation|DRUG: cyclophosphamide|DRUG: mycophenolate mofetil|DRUG: busulfan|DRUG: cyclosporine|DRUG: fludarabine phosphate|PROCEDURE: peripheral blood stem cell transplantation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|OTHER: laboratory biomarker analysis|GENETIC: cytogenetic analysis|OTHER: flow cytometry|GENETIC: fluorescence in situ hybridization|OTHER: pharmacological study|GENETIC: polymorphism analysis|DRUG: tacrolimus|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Rhamnosus and PCOS Treatment
Status: COMPLETED
Conditions: Insulin Resistance|Polycystic Ovary Syndrome|Hyperandrogenism|Obesity
Interventions: DIETARY_SUPPLEMENT: Lactobacillus group|DIETARY_SUPPLEMENT: Dietary group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RC48-ADC Combined With Cadonilimab（AK104）in the Treatment of HER2-expression Locally Advanced or Metastatic Urothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: RC48-ADC|DRUG: AK104
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DKN-01 in Combination With Tislelizumab ± Chemotherapy in Patients With Gastric or Gastroesophageal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|Gastric Adenocarcinoma|GastroEsophageal Cancer
Interventions: DRUG: DKN-01 300mg|DRUG: DKN-01 600mg|DRUG: DKN-01 400mg|DRUG: Tislelizumab 200mg|DRUG: Tislelizumab 400mg|DRUG: Oxaliplatin|DRUG: Capecitabine 1000mg/ m2 BID|DRUG: Leucovorin Calcium|DRUG: Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atropine for Children and Adolescent Myopia Progression Study
Status: UNKNOWN
Conditions: Myopia
Interventions: DRUG: Atropine Sulfate 1 % Ophthalmic Ointment and Atropine Sulfate 0.01% Eye Drop|DRUG: atropine 0.01% eye drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Coffee Main Constituents (Caffeine and Chlorogenic Acid) Supplementation on Inflammatory, Metabolic Factors, Hepatic Steatosis and Fibrosis in None- Alcoholic Fatty Liver Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Nonalcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: caffeine and chlorogenic acid|DIETARY_SUPPLEMENT: caffeine|DIETARY_SUPPLEMENT: chlorogenic acid|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of FRAME FR for AVF Repair in High-Flow Reduction & Stabilization, A Prospective Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Arteriovenous Fistula
Interventions: DEVICE: FRAME FR IFU
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of the Ability of Spyglass Cholangioscopy to Facilitate Radiation Free ERCP
Status: COMPLETED
Conditions: Choledocholithiasis|Biliary Obstruction
Interventions: PROCEDURE: Cholangioscopy|DEVICE: Spyglass DS Cholangioscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Multiple Myeloma
Interventions: DRUG: MLM-CAR44.1 T-cells at day 0 Single intravenous infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-19 in Healthy and Immunocompromised Adults
Status: COMPLETED
Conditions: Infections, Respiratory|Virus Diseases|Infection Viral|Vaccine Adverse Reaction|RNA Virus Infections|Protection Against COVID-19 and Infections With SARS CoV 2
Interventions: BIOLOGICAL: BNT162a1|BIOLOGICAL: BNT162b1|BIOLOGICAL: BNT162b2|BIOLOGICAL: BNT162c2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)
Status: COMPLETED
Conditions: Hibernation, Myocardial|Complete Occlusion of Coronary Artery
Interventions: DEVICE: stenting or balloon expansion|DRUG: aspirin, clopidogrel, ticagrelor, atorvastatin, rosuvastatin, betaloc
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable Sensors and Molecular Omics to Detect and Mitigate Cell Therapy Adverse Events
Status: RECRUITING
Conditions: Hodgkin Lymphoma|Non Hodgkin Lymphoma|Leukemia|Multiple Myeloma
Interventions: DEVICE: Biostrap arm band
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dexmedetomidine Use in ICU Sedation and Postoperative Recovery in Elderly Patients and Post-cardiac Surgery
Status: UNKNOWN
Conditions: Delirium|Cognitive Decline|Post-operative Quality of Recovery
Interventions: DRUG: propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza
Status: RECRUITING
Conditions: Influenza
Interventions: DRUG: sirolimus and oseltamivir|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of TNNT1-Myopathy With L-Tyrosine.
Status: UNKNOWN
Conditions: Nemaline Myopathy
Interventions: DRUG: L-Tyrosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT