pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Digital Manometry for Intra-Abdominal Pressure Measurement in Ileus
Status: COMPLETED
Conditions: Ileus
Interventions: DEVICE: Digital Manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy
Status: COMPLETED
Conditions: Contraception
Interventions: DEVICE: Vaginal Ring - intermittent regimen|DEVICE: Vaginal Ring - continuous regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Oral Estradiol and Progesterone Therapy on Vaginal Cytokines in Postmenopausal Women
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: oral estradiol 1.0 mg|DRUG: oral progesterone 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Breaking Down Care Process and Patient-level Barriers to Arteriovenous Access Creation Prior to Hemodialysis Initiation
Status: COMPLETED
Conditions: Chronic Kidney Disease|Chronic Kidney Disease Requiring Chronic Dialysis
Interventions: OTHER: Vascular Access Navigation and Education Quality Improvement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Community Health Worker And MHealth to ImProve Viral Suppression (CHAMPS Pilot)
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DEVICE: Wise App with medication adherence reminders|BEHAVIORAL: CHW Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vortioxetine on Cognitive Dysfunction in Adult Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Vortioxetine (Lu AA21004)|DRUG: Vortioxetine (Lu AA21004)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of the Therapies of Resolution of Problem in the Care of the Natural Caregivers of Patients Affected by Neurodegenerative Disease Living at Home
Status: WITHDRAWN
Conditions: Neurodegenerative Diseases
Interventions: BEHAVIORAL: Occupational Therapy Assessment|BEHAVIORAL: Psychological Assessment|BEHAVIORAL: Problem Solving Therapy|BEHAVIORAL: Speaking group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of the Use of Sealed Capsule Irrigation With Sodium Chloride During Pediatric Cataract Surgery and IOL Implantation
Status: WITHDRAWN
Conditions: Cataract Extraction
Interventions: PROCEDURE: Cataract surgery with Perfect Capsule and Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rotation-advancement and Straight-line Surgical Approaches in Repairing Unilateral Cleft Lip Defect
Status: COMPLETED
Conditions: Unilateral Cleft Lip
Interventions: PROCEDURE: Advancement-rotation approach based on Millard' for repairing lip defect.|PROCEDURE: Straight-line approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Diabetes and Depression in Hispanics and African Americans and Its Effect on A1c and Quality of Life.
Status: COMPLETED
Conditions: Diabetes|Depression
Interventions: DRUG: sertraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Status: COMPLETED
Conditions: Pain, Postoperative|Opioid Use
Interventions: PROCEDURE: Epidural Analgesia|DRUG: Lidocaine Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Persistence of Antibodies and Kinetics of B Cell Response in Healthy Children After Vaccination With MCC Vaccine
Status: COMPLETED
Conditions: Prevention of Meningococcal Infection
Interventions: BIOLOGICAL: Meningococcal C conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endovenous Radiofrequency Versus Laser Ablation for the Treatment of Great Saphenous Vein Reflux
Status: COMPLETED
Conditions: Varicose Veins
Interventions: OTHER: radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy in Epithelial Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Carcinoma|Peritoneal Carcinoma
Interventions: DRUG: carboplatin and paclitaxel followed by surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD
Status: COMPLETED
Conditions: Corneal Endothelial Cell Loss|Ocular Pain|Ocular Inflammation|Cataract Surgery
Interventions: DRUG: Vehicle Ophthalmic Solution|DRUG: Omaveloxolone Ophthalmic Suspension 0.5%|DRUG: Omaveloxolone Ophthalmic Suspension 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Mobile-Based Education on Self-Care, Quality of Life and Complications in Patients With Intestinal Stoma
Status: NOT_YET_RECRUITING
Conditions: Intestinal Stoma Site Hemorrhage|Intestinal Stoma Leakage|Life Style, Healthy
Interventions: BEHAVIORAL: Mobile-based stoma care education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Anti-Oxidants and Anti-inflammatory Agents in Glaucoma and Diabetic Retinopathy
Status: TERMINATED
Conditions: Open-angle Glaucoma|Diabetic Retinopathy
Interventions: DRUG: GlaucoHealth|DRUG: GlaucoSelect|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wound Infection Due to Suture Material in Caesarean Skin Incision and Evaluation of Cosmetic Results
Status: COMPLETED
Conditions: Cesarean Section; Infection|Scar
Interventions: OTHER: Evaluation of the wound infection at the 10th day post-op check-up among all groups|OTHER: Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups|OTHER: Evaluation of the cosmetic results of the incision line at the 6th month post-op check-up among all groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Islet Cell Transplant|DRUG: Islet Cell Transplant plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Zn-containing Granulate on Patient Morbidity and Wound Healing After Free Gingival Graft Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: PROCEDURE: Zn granulate stent after FGG surgery|PROCEDURE: Hemostatic agent suturing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education and Counseling Based on HypnoBreastfeeding
Status: COMPLETED
Conditions: Hypno-breastfeeding Education
Interventions: BEHAVIORAL: Hypno-breastfeeding Education|BEHAVIORAL: Experimental: Standart Breastfeeding Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-Label Treatment Protocol to Provide Metreleptin for the Treatment of Diabetes Mellitus and/or Hypertriglyceridemia Associated With Lipodystrophy
Status: COMPLETED
Conditions: Lipodystrophy
Interventions: DRUG: metreleptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Prebiotic Activity of Arabinoxylan-Oligosaccharides in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: arabinoxylan-oligosaccharides (AXOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Of GSK189254 And Duloxetine In The Electrical Hyperalgesia Model Of Healthy Volunteers
Status: COMPLETED
Conditions: Hyperalgesia
Interventions: DRUG: Duloxetine|DRUG: GSK189254|DRUG: GSK189254 Placebo|DRUG: Duloxetine Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Biologic Therapy to Prevent Osteoarthritis After ACL Injury
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: DRUG: Anakinra injection|PROCEDURE: sterile saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide Releasing Solution (NORS) For The Treatment Of Human Papillomavirus(HPV) Verrucae Plantaris (Plantar Warts)
Status: COMPLETED
Conditions: Verruca Plantaris
Interventions: OTHER: Sterile water foot bath|DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can an Array of Micro-electrodes Implanted in a Human Nerve Record Neural Signals and Provide Feedback?
Status: RECRUITING
Conditions: Amputation
Interventions: DEVICE: percutaneous Utah Slanted Electrode Arrays (pUSEAs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Induced Changes in Ventilatory Responsiveness and Altitude Exposure
Status: TERMINATED
Conditions: Effects of High Altitude|Hypoxia|Inadequate or Impaired Breathing Pattern or Ventilation|Abnormal Blood Oxygen Pressure
Interventions: DRUG: NAC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Syndromes|Keratoconjunctivitis Sicca
Interventions: DRUG: rebamipide 2% ophthalmic suspension|DRUG: placebo eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 Weeks
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Pioglitazone 15 mg|DRUG: Pioglitazone 45 mg|DRUG: Pioglitazone 30 mg|DRUG: Linagliptin 5mg / Pioglitazone 45 mg FDC|DRUG: Linagliptin 5mg / Pioglitazone 30 mg FDC|DRUG: Linagliptin 5mg|DRUG: Linagliptin 5mg / Pioglitazone 15 mg FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043
Status: WITHDRAWN
Conditions: Safety|Tolerability|Pharmacokinetics|Sedation
Interventions: DRUG: AZD3043
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECT OF MYOFASCIAL RELEASE ON SCOLIOTIC CURVATURE AND PREMENSTRUAL SYMPTOMS IN FEMALES WITH DYSMENORRHEA
Status: RECRUITING
Conditions: Scoliosis Idiopathic Adolescent|Dysmenorrhea|Premenstrual Syndrome|Quality of Life
Interventions: OTHER: Myofascial release.|OTHER: Traditional exercises for scoliosis treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JR-141 in Patients With Mucopolysaccharidosis II
Status: COMPLETED
Conditions: Mucopolysaccharidosis II
Interventions: DRUG: JR-141|DRUG: JR-141|DRUG: JR-141
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of GSK Biologicals HIV Vaccine in Antiretroviral Therapy (ART)-naïve HIV-1 Infected Persons
Status: COMPLETED
Conditions: AIDS
Interventions: BIOLOGICAL: GSK Biologicals HIV Vaccine 732462|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Baricitinib (LY3009104)Treatment in Japanese Participants With Active Rheumatoid Arthritis on Background Methotrexate Therapy
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Placebo|DRUG: Baricitinib|DRUG: Baricitinib|DRUG: Baricitinib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Physiological Assessment of a Nearly Ultra-protective Lung Ventilation Strategy: A Quasi-experimental Preliminary Study in ARDS Patients
Status: COMPLETED
Conditions: ARDS|Volumetric Capnography
Interventions: OTHER: protective mechanical ventilation strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Re-treatment With 177Lu-PSMA-617 for the Treatment of Metastatic Castration-Resistant Prostate Cancer, RE-LuPSMA Trial
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Gallium Ga 68 Gozetotide|DRUG: Lutetium Lu 177 Vipivotide Tetraxetan|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|PROCEDURE: Single Photon Emission Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Return to Baseball After BFR Therapy for Shoulder Injury
Status: WITHDRAWN
Conditions: Musculoskeletal Injury
Interventions: DEVICE: Blood Flow Restriction Therapy|OTHER: Standard physical rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Longitudinal Biocollection in Thoracic Oncology, Including Newly Diagnosed Lung Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Carcinoma, Non-Small-Cell Lung|Small Cell Lung Carcinoma|Metastatic Lung Cancer
Interventions: OTHER: Blood Sampling (2*8mL Tubes)|OTHER: PBMC Sampling (1*8mL Tubes)|OTHER: Paxgene Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunotherapy With Nivolumab or Nivolumab Plus Ipilimumab vs. Double Placebo for Stage IV Melanoma w. NED
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Nivolumab + Placebo|DRUG: Nivolumab + Ipilimumab|DRUG: Double Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea-hypopnea Syndrome (SAHS) and Ventricular Arrhythmias
Status: COMPLETED
Conditions: Sleep Apnea|Ventricular Arrythmias|Systolic Left Ventricle Dysfunction
Interventions: DEVICE: Nasal continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia
Status: COMPLETED
Conditions: Anesthetic Ventilatory Requirements
Interventions: DEVICE: Anesthetic Conserving Device (AnaConDa )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study on the Efficacy and Safety of a Novel Tripterygium Wilfordii Preparation in Reducing Proteinuria in Patients With Diabetic Nephropathy
Status: RECRUITING
Conditions: Diabetic Nephropathy
Interventions: DRUG: Kunxian capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: APL-501 or Nivolumab in Combination With APL-101 in Locally Advanced or Metastatic HCC and RCC
Status: TERMINATED
Conditions: Hepatocellular Carcinoma|Renal Cell Carcinoma
Interventions: BIOLOGICAL: APL-501|DRUG: APL-101|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Low-dose Naltrexone in Patients With Different Types of Vulvodynia
Status: RECRUITING
Conditions: Vulvodynia|Naltrexone|Quality of Life
Interventions: DRUG: Naltrexone Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two Different Distraction Methods on Pain and Fear During Venipuncture in Children
Status: COMPLETED
Conditions: Venipuncture Site Reaction|Procedural Complication|Nursing Caries
Interventions: DEVICE: Virtual Reality Box|DEVICE: Tablet Computer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Methylsulfonylmethane Supplementation on Osteoarthritis of The Knee: A Randomized Controlled Study
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Methylsulfonylmethane (MSM)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Heparin Solution Versus Anti-adhesion Barrier Gel for Intrauterine Adhesions Prevention After Operative Hysteroscopy
Status: RECRUITING
Conditions: Intrauterine Adhesion
Interventions: DRUG: Heparin solution|DRUG: Anti-adhesion barrier gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Thyroid Hormone Replacement for Subclinical Hypothyroidism and Chronic Heart Failure (ThyroHeart-CHF)
Status: UNKNOWN
Conditions: Heart Failure|Subclinical Hypothyroidism
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Pharmacokinetic Drug Interaction and Safety of CKD-501, D745 and D150
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: CKD-501|DRUG: D745, D150|DRUG: CKD-501, D745, D150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Non-comparative Study to Document the Tolerability to Ramipril in Patients With at Least One High Risk for Developing a Major Cardiovascular Event
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: RAMIPRIL HOE498
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer
Interventions: DRUG: vitamin C|DEVICE: Modulated Electro-Hyperthermia (mEHT)|OTHER: Supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodynamic-GUIDEd Management of Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Heart Failure, Systolic|Heart Failure, Diastolic|Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class IV|Heart Failure，Congestive|Heart Failure With Reduced Ejection Fraction|Heart Failure With Normal Ejection Fraction|Heart Failure; With Decompensation
Interventions: DEVICE: CardioMEMS™ HF System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ocular Availability in Human Tears After Topical Administration of 1.5% Levofloxacin Compared to Active Comparators
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 1.5% levofloxacin ophthalmic solution|DRUG: 0.5% moxifloxacin hydrochloride ophthalmic solution|DRUG: 0.3% gatifloxacin ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study to Assess an Advanced Skin Protectant in the Management of Incontinence-associated Dermatitis
Status: TERMINATED
Conditions: Incontinence-associated Dermatitis
Interventions: DEVICE: Cavilon Advanced Skin Protectant|DEVICE: IAD Hospital Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation With Sterile Irrigated Deflectable Ablation Catheter Used in Renal Artery in Primary Hypertension
Status: UNKNOWN
Conditions: Primary Hypertension
Interventions: DEVICE: Renal denervation|DIAGNOSTIC_TEST: Renal angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gene Study for Infantile Onset Diabetes
Status: UNKNOWN
Conditions: Study Genetic Basis of Infantile Onset Diabetes Mellitus
Interventions: GENETIC: Human Leucocytic antigen typing and mutation of adenosine triphosphate sensitive K channel gene in diabetic patients diagnosed under the age of one year.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine?
Status: COMPLETED
Conditions: Headache|Acute, Focal Neurologic Disease|Severely Elevated Blood Pressure|Acute Visual Loss
Interventions: PROCEDURE: Use of Non-dilated retinal photography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Sober Network IPT for Perinatal Women With Comorbid Substance Use and Depression
Status: COMPLETED
Conditions: Perinatal Depression, Substance Use
Interventions: BEHAVIORAL: Sober Network Interpersonal Psychotherapy (IPT)|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Regenerative Stem Cell Therapy for Stroke in Europe
Status: WITHDRAWN
Conditions: Stroke
Interventions: OTHER: Adipose Derived Stem Cells|OTHER: Vehicle media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel+Carboplatin vs Epirubicin+Cyclophosphamide Followed by Docetaxel as Adjuvant Treatment in Triple-negative Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: EC-T|DRUG: TP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Feasibility Study With ADAPT 3D - ALR for Aortic Leaflet Repair
Status: UNKNOWN
Conditions: Aortic Stenosis|Aortic Insufficiency
Interventions: DEVICE: Implantation of ADAPT 3D ALR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Safety and Efficacy of a Moisturizer Body Lotion in Adults of Atopic Dermatitis.
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: Moisturizer Body Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adequate Dosage of Sugammadex on Thyroid Surgery
Status: COMPLETED
Conditions: Thyroid Surgery
Interventions: DRUG: Sugammadex 200 MG in 2 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Gynaecology Exercise and Mindfulness Study
Status: UNKNOWN
Conditions: Gynecologic Cancer|Uterus Cancer|Ovary Cancer|Cervical Cancer|Vaginal Cancer|Vulvar Cancer
Interventions: BEHAVIORAL: Mindfulness and exercise|BEHAVIORAL: Mindfulness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emergence Delirium and Recovery Time in Children
Status: UNKNOWN
Conditions: Emergence Delirium
Interventions: DIAGNOSTIC_TEST: PAEDS|PROCEDURE: TIVA|PROCEDURE: Inhalational anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis
Status: COMPLETED
Conditions: Mydriasis|Dilation
Interventions: DRUG: Phentolamine Ophthalmic Solution 0.75%|OTHER: Phentolamine Ophthalmic Solution Vehicle (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transfusion Requirements in Gastrointestinal (GI) Bleeding
Status: UNKNOWN
Conditions: Upper Gastrointestinal Bleeding|Cirrhosis|Portal Hypertension
Interventions: PROCEDURE: red blood cell transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous and Allogeneic Transplant for Relapsed Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Hodgkins Disease
Interventions: DRUG: Fludarabine|DRUG: Busulfan|DRUG: Anti-Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®
Status: COMPLETED
Conditions: Refractive Error
Interventions: DEVICE: Delefilcon A contact lenses|DEVICE: Senofilcon A contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early-warning Intervention for Heat Waves and Cold Spells in Older Hypertensive Patients
Status: RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Information notification based on the health warning system for heat waves and cold spells|DEVICE: The electrocardiography(ECG) and blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Combivent vs. Salbutamol in Patients With Metacholine Induced Bronchospasm
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Salbutamol sulfate/Ipratropium bromide|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness & Stress Management Study for Cardiac Patients
Status: COMPLETED
Conditions: Heart Diseases|Heart Failure|Myocardial Infarction|Chronic Stable Angina|Coronary Artery Bypass|Angioplasty
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Pulsed Radiofrequency for Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: Pulsed radiofrequency (PRF)|DRUG: Xylocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Insomnia|Depression
Interventions: BEHAVIORAL: Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CBD for Chronic Radicular Pain on Chronic Opioid Therapy (COT)
Status: COMPLETED
Conditions: Radiculopathy
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Different Doses of Hyaluronic Acid Injections in Knee Osteoarthritis.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Intra-articular 20 mg, 1.0% Hyaluronic Acid Injection|OTHER: Intra-articular 32 mg, 1.6% Hyaluronic Acid Injection|OTHER: Intra-articular 48 mg, 2.0% Hyaluronic Acid Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pessary Versus Cerclage With or Without Progesterone in Twins
Status: TERMINATED
Conditions: Preterm Birth|Twin Pregnancy|Short Cervix
Interventions: DEVICE: Pessary|PROCEDURE: Cervical cerclage|DRUG: Vaginal progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Local Paclitaxel or Balloon Angioplasty Below the Knee
Status: UNKNOWN
Conditions: Stenosis|Occlusion|Restenosis
Interventions: DEVICE: SequentPlease OTW paclitaxel coated balloon catheter|DEVICE: conventional uncoated balloon for BTK endovascular therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Topical Permethrin 5% and Oral Ivermectin for the Treatment of Scabies
Status: COMPLETED
Conditions: Scabies
Interventions: DRUG: Ivermectin Tablets|DRUG: Permethrin Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Oral Administration of ASP7991 to Non-elderly Male Subjects
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of ASP7991
Interventions: DRUG: ASP7991|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of a Plant-blend Protein Isolate on Post-exercise Myofibrillar Protein Synthesis
Status: COMPLETED
Conditions: Muscle Metabolism
Interventions: BEHAVIORAL: Bilateral resistance exercise|DIETARY_SUPPLEMENT: Whey protein|DIETARY_SUPPLEMENT: Plant-blend protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Urine Samples Obtained by Bladder Stimulation for the Diagnosis of Urinary Tract Infection in Infants
Status: COMPLETED
Conditions: Urinary Tract Infection Bacterial
Interventions: DEVICE: urinary catheterization|PROCEDURE: manual bladder stimulation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis
Status: RECRUITING
Conditions: Drug Effect|Pulpitis - Irreversible
Interventions: DRUG: Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Training Parents of Children With ADHD by Mindfulness-based Stress Reduction for Reducing Stress
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness-based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase 2 Study of Cediranib in Combination With Olaparib in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Metastatic Lung Non-Small Cell Carcinoma|Metastatic Lung Small Cell Carcinoma|Metastatic Pancreatic Adenocarcinoma|Metastatic Triple-Negative Breast Carcinoma|Pancreatic Ductal Adenocarcinoma|Stage III Breast Cancer AJCC v7|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage III Lung Small Cell Carcinoma AJCC v7|Stage III Pancreatic Cancer AJCC v6 and v7|Stage IIIA Breast Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Small Cell Carcinoma AJCC v7|Stage IIIB Breast Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Small Cell Carcinoma AJCC v7|Stage IIIC Breast Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Lung Non-Small Cell Cancer AJCC v7|Stage IV Lung Small Cell Carcinoma AJCC v7|Stage IV Pancreatic Cancer AJCC v6 and v7|Triple-Negative Breast Carcinoma|Unresectable Lung Small Cell Carcinoma|Unresectable Pancreatic Adenocarcinoma|Unresectable Pancreatic Carcinoma|Unresectable Triple-Negative Breast Carcinoma
Interventions: OTHER: 18F-Fluoromisonidazole|DRUG: Cediranib Maleate|OTHER: Laboratory Biomarker Analysis|DRUG: Olaparib|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BRAVO Study for Functional Dyspepsia
Status: COMPLETED
Conditions: Dyspepsia|Gastroesophageal Reflux
Interventions: DRUG: Esomeprazole 20mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and the Pharmacokinetic Study of Characteristics of MKT-N2 (Montelukast) and Singulair® (Montelukast Sodium)to Treat Asthma
Status: COMPLETED
Conditions: Asthma and Allergic Rhinitis
Interventions: DRUG: Montelukast|DRUG: Montelukast sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Single-used Versus MultiPlE-used Endotracheal suCtIon cAtheters in Mechanically ventiLated ICU Patients
Status: RECRUITING
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: Suction Circuit Flushing with Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of Drug-drug Interaction of Nintedanib and Ketoconazole in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Ketoconazole|DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking, Tobacco
Interventions: DRUG: 2-[18F]-FA PET/CT|DRUG: I.V. Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Using Transcranial Direct Current Stimulation (tDCS) to Enhance the Benefit of Movement Training in Stoke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Visumotor Upper Extremity Training|OTHER: Anodal/Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: MNI-330 as a brain SPECT tracer of Beta-Amyloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic and Prognostic Value of p16INK4a Expression in Low Grade Squamous Intraepithelial Lesions of the Cervix.
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia Grade 1 (CIN 1)
Interventions: PROCEDURE: colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Optimal Concentration of Dermatophagoides Pteronyssinus (Dp) Allergen Extract for Skin Prick Test (SPT) of Thai Population
Status: UNKNOWN
Conditions: Rhinitis, Allergic, Perennial|Rhinitis, Allergic, Seasonal|Skin Prick Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Helmet Continuous Positive Airway Pressure (CPAP) Versus Oxygen Venturi in Severe Acute Respiratory Failure in Pneumonia
Status: COMPLETED
Conditions: Pneumonia|Respiratory Insufficiency
Interventions: OTHER: Oxygen therapy|OTHER: Helmet CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic Assessment of SARS-CoV-2 Neurotropic Capacity in Modestly and Critically Ill Patients, and Patients Who Died From COVID-19
Status: COMPLETED
Conditions: COVID-19 Disease
Interventions: OTHER: Data collection from lumbar puncture|OTHER: Data collection from blood draw|OTHER: CNS magnetic resonance imaging (MRI) imaging|OTHER: Microscopy of defined brain regions on autopsy specimens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ilioinguinal Nerve Block in Transcatheter Aortic Valve Implantation
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Lidocaine|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of COLAL-PRED® in the Treatment of Moderate Acute Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: COLAL-PRED®|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies
Status: COMPLETED
Conditions: Lymphoma, B-Cell|T-Cell Lymphoma
Interventions: DRUG: RP6530
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Purification Therapy With Dual-cannula in Jugular-femoral Venous
Status: NOT_YET_RECRUITING
Conditions: Blood Purification|Dual-cannula|Vena Cava Disconnection
Interventions: DEVICE: Hemodialysis Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
Status: UNKNOWN
Conditions: HIV Prevention|Pre-exposure Prophylaxis (PrEP)|Risk Reduction|Adherence, Medication
Interventions: BEHAVIORAL: PrEP-3D package|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Horizontal Bone Augmentation of Alveolar Ridge
Status: COMPLETED
Conditions: Platelet-rich Fibrin|Bone Substitutes|Atrophic Maxilla|Cone-beam Computed Tomography|Bone Regeneration
Interventions: PROCEDURE: Horizontal Bone Augmentation of Alveolar Ridge|PROCEDURE: Groups|PROCEDURE: Dental Implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3039478 in Combination With Dexamethasone in Participants With T-ALL/T-LBL
Status: COMPLETED
Conditions: T-cell Acute Lymphoblastic Leukemia|T-cell Lymphoblastic Lymphoma
Interventions: DRUG: LY3039478|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of INCB040093 in Subjects With Previously Treated B-Cell Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: B-cell Malignancies
Interventions: DRUG: INCB040093|DRUG: INCB040093 + itacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Glucose Monitoring (CGM) With a Low Carbohydrate Diet to Reduce Weight in Patients With Pre-Diabetes
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: OTHER: Normal Diet|OTHER: Low carb diet|DEVICE: CGM with no real time feedback|DEVICE: CGM with real time feedback)|BEHAVIORAL: Education material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stromal Vascular Fraction (SVF) for Treatment of Enterocutaneous Fistula (HULPUTC)
Status: UNKNOWN
Conditions: Enterocutaneous Fistula
Interventions: DRUG: Adipose-derived stem cells without expanded
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose Derived Stem Cells (ADSC) Enriched Fat Grafts
Status: COMPLETED
Conditions: Breast Reconstruction|Contour Irregularities|Volume Insufficiency
Interventions: GENETIC: centrifuged fat graft|GENETIC: ADSCs enriched fat graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety, Pharmacokinetics/Pharmacodynamics (PK/PD) and Food Effect Of LC51-0255
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LC51-0255|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax|DRUG: Gemtuzumab|DRUG: Ziftomenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supplements for Controlling Resistance to Insulin
Status: TERMINATED
Conditions: Obesity|Diabetes Mellitus, Type 2
Interventions: DRUG: nutrition education plus active supplement|DRUG: nutrition education plus inactive supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders.
Status: COMPLETED
Conditions: Antibiotic-associated Loose/Watery Stools
Interventions: DIETARY_SUPPLEMENT: Probiotic capsules|DIETARY_SUPPLEMENT: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation
Status: COMPLETED
Conditions: Sleep Deprivation
Interventions: DRUG: Placebo|DRUG: Modafinil|DRUG: THN102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 6 microRNA Tool for Stratifying Stage II Colon Cancer of Receiving Adjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Colonic Neoplasms|Effects of Chemotherapy
Interventions: OTHER: A 6 microRNA stratified tool|OTHER: A classic stratified tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: