pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Hormone Receptor-Positive Breast Carcinoma
Interventions: OTHER: Best Practice|PROCEDURE: Biospecimen Collection|PROCEDURE: Endocrine Drug Therapy|BEHAVIORAL: Health Education|OTHER: Questionnaire Administration|OTHER: Symptom Specific Assessment Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Escalation and Expansion Study of CM313 in Subjects With Relapsed or Refractory Multiple Myeloma and Lymphoma
Status: UNKNOWN
Conditions: Multiple Myeloma|Lymphoma
Interventions: DRUG: CM313-Dose escalation|DRUG: CM313|DRUG: Dexamethasone|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lutonix® Drug Coated Balloon vs. Standard Balloon Angioplasty for Treatment of Femoropopliteal In-Stent Restenosis
Status: COMPLETED
Conditions: Femoral Artery Stenosis|Femoral Artery Occlusion|Restenosis
Interventions: DEVICE: Lutonix DCB|DEVICE: Standard Uncoated Balloon Angioplasty Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: OTHER: Bakuchiol and Ethyl Linoleate|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Melatonin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Carboxymethylcellulose Based Eye Drop|DRUG: Carboxymethylcellulose Sodium 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of an iPhone-based Event Recorder for Arrhythmia Detection
Status: COMPLETED
Conditions: Arrhythmia, Palpitations, Lightheadedness
Interventions: DEVICE: Alivecor monitor and 14 day event monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Comparison of Morning Versus Bedtime Administration of Aspirin: A Cardiovascular Circadian Chronotherapy (C3) Trial
Status: RECRUITING
Conditions: Atherosclerosis|Cardiovascular Diseases|Drug Effect
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Iron Therapy for Patients With Anemia After Caesarean Section
Status: TERMINATED
Conditions: Postoperative Anaemia
Interventions: DRUG: Ferinject|DRUG: Ferrous fumarate|DRUG: Placebo for ferrous fumarate|DRUG: Placebo for ferinject
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
Status: COMPLETED
Conditions: Inflammation|Pain|Cataract
Interventions: DRUG: XG-102|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effects of Non Digestible Carbohydrates on Long-Term Glucose Homeostasis in Untreated Prediabetic Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre Diabetes|Prediabetic State|Dysglycemia|PreDiabetes
Interventions: DIETARY_SUPPLEMENT: Non digestible carbohydrates|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epirubicin Cisplatin and Fluorouracil (FU) Combined With Endostar in Patients With Advanced or Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: ECF-endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applied Forces During Neonatal Intubation at Different Heights of the Resuscitation Table
Status: NOT_YET_RECRUITING
Conditions: Neonatal Disease|Intubation
Interventions: DEVICE: Direct laryngoscope and table at xiphoid level|DEVICE: Videolaryngoscope and table at xiphoid level|DEVICE: Direct laryngoscope and table at umbilical level|DEVICE: Videolaryngoscope and table at umbilical level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mini-Allogeneic Peripheral Blood Progenitor Cell Transplantation For Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fludarabine|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Management of Risk Factors in the Elderly Patients
Status: RECRUITING
Conditions: Perioperative Cardiavascular Complication|Peroperative Complication|Perioperative Pulmonary Complication|Perioperative Neurological Complication
Interventions: OTHER: Implementing risk management and control plan for the elderly during perioperative period
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Preoperative MM-121 With Paclitaxel in HER2-negative Breast Cancer
Status: COMPLETED
Conditions: ER Positive, Her2 Negative Breast Cancer Patients|Triple Negative Breast Cancer Patients
Interventions: DRUG: MM-121|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Advanced Multi-Parameter Reporting in Patients Wearing a Novel Device: Utilization During Cardiac Rehabilitation
Status: WITHDRAWN
Conditions: Heart Attack|Cardiac Event|Cardiac Disease|Cardiac Infarct|NSTEMI|STEMI
Interventions: DEVICE: ZOLL Arrhythmia Management System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imatinib Mesylate With or Without Surgery in Treating Patients With Metastatic Gastrointestinal Stromal Tumor That is Responding to Imatinib Mesylate
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion
Status: COMPLETED
Conditions: Tooth Erosion
Interventions: DRUG: Sodium fluoride|DRUG: Sodium monoflurophosphate|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME.
Status: COMPLETED
Conditions: Wet Macular Degeneration|Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: DRUG: Dorzolamide-timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple Ascending Doses MY008211A in Healthy Adults
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: MY008211A tablets|DRUG: MY008211A tablets matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention With Omega-3 in Children With Attention Deficit Hyperactivity Disorder(ADHD)
Status: ACTIVE_NOT_RECRUITING
Conditions: ADHD|ADD
Interventions: DIETARY_SUPPLEMENT: Calanus oil|OTHER: Medical Paraffin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAP-BAND Observational Cohort
Status: UNKNOWN
Conditions: Epworth Sleepiness Scale|Glycemic Control|Liver Function|Inflammation|Iron and Bone Turnover|SF-36|IW-QOL Lite HRQoL
Interventions: DEVICE: LAP-BAND System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Urothelial Carcinoma
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Reliability, Validity, and Responsiveness of the Static Balance Test in Patients With Multiple Sclerosis.
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Static Balance Test|OTHER: Berg Balance Scale|OTHER: Timed Up an Go Test|OTHER: Four Square Step Test|OTHER: Functional Reach Test|OTHER: One-leg Stance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics of HCP1401 and Co-administration of HCP0605, HGP1405 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HCP0605|DRUG: HGP1405|DRUG: HCP1401
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness of Escitalopram to Prevent Depression in Head and Neck Cancer Patients Receiving Treatment
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via TWISTHALER® Device in Adult and Adolescent Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: indacaterol|DRUG: formoterol|DRUG: placebo to indacaterol|DRUG: placebo to formoterol|DRUG: short acting β2-agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cabiralzumab Given by Itself or With Nivolumab in Advanced Cancer or Cancer That Has Spread
Status: COMPLETED
Conditions: Advanced Malignancies
Interventions: BIOLOGICAL: Cabiralizumab|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: adalimumab 40 mg|BIOLOGICAL: sirukumab 100 mg|BIOLOGICAL: sirukumab 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Administration of Brimonidine in Intravitreal Anti-VEGF Therapy
Status: COMPLETED
Conditions: Post-Injection Intraocular Pressure Spikes
Interventions: DRUG: topical brimonidine tartrate 0.15% (Alphagan® P; Allergan, Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rivaroxaban Plus Aspirin in Patients With Chronic Coronary Syndrome and High Ischemic Risk
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)|Peripheral Arterial Disease (PAD)
Interventions: DRUG: Rivaroxaban 2.5 MG [Xarelto]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of a New Acoustic Feedback Canceller in Hearing Aids With the Current System
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid Mermaid Current|DEVICE: Hearing Aid Mermaid New|DEVICE: Power Hearing Aid Current|DEVICE: Power Hearing Aid New
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Escitalopram and Duloxetine in Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Study the COVAC-1 Booster Dose in Generally Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Interventions: BIOLOGICAL: COVAC-1|BIOLOGICAL: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nepafenac Once Daily for Macular Edema - Study 1
Status: COMPLETED
Conditions: Non-Proliferative Diabetic Retinopathy|Cataract
Interventions: DRUG: Nepafenac Ophthalmic Suspension, 0.3%|OTHER: Nepafenac vehicle|DRUG: Prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy, Safety and Tolerability of Two Different 810 nm Diode Lasers for Hair Reduction
Status: COMPLETED
Conditions: Hypertrichosis
Interventions: DEVICE: Soprano/SHR|DEVICE: LightSheer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Exercise Program on Cognition and Brain in Overweight/Obese Preadolescent Children
Status: COMPLETED
Conditions: Cognitive Function 1, Social|Mental Health Wellness 1|Obesity|Overweight
Interventions: BEHAVIORAL: A 5-months physical exercise-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Recurrent Glioma|Solid Tumor
Interventions: DRUG: GNC-039
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Analysis of Global Proteome in Bone Samples From Patients With Osteoporotic and Nonosteoporotic Fracture
Status: UNKNOWN
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: total hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1 First-in-human Study of JS014
Status: RECRUITING
Conditions: Neoplasm Malignant|Neoplasm, Experimental|Solid Tumor, Adult|Lymphoma
Interventions: BIOLOGICAL: JS014, Interleukin 21 and humanized anti-human serum albumin VHH antibody|BIOLOGICAL: Pembrolizumab - anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of DP Followed by FOLFIRI or the Reverse Sequence in Unresectable Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Metastases
Interventions: DRUG: DP|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early High-volume Continuous Veno-venous Hemofiltration for Patients With Severe Acute Pancreatitis
Status: UNKNOWN
Conditions: Acute Pancreatitis
Interventions: DEVICE: AN69 hemofilter|OTHER: conventional treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shock Testing to Unmask RV Lead and GEnerator Malfunction in ICD Patients: the SURGE-ICD Registry
Status: RECRUITING
Conditions: Implantable Defibrillator Lead Dysfunction|Implantable Automatic Defibrillator Malfunction|Implantable Defibrillator User
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Iodine + Isopropyl Alcohol Versus Iodine + Antimicrobial Sealant for Skin Preparation
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DEVICE: 2-octyl cyanoacrylate [InteguSEAL®]|DEVICE: Iodine povacrylex in isopropyl alcohol [Duraprep®, 3M]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Alipogene Tiparvovec for the Treatment of LPLD Patients
Status: WITHDRAWN
Conditions: LPL Deficiency
Interventions: DRUG: alipogene tiparvovec|DRUG: Prednisolone|DRUG: Cyclosporins|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Non-erosive Gastroesophageal Reflux Disease
Interventions: DRUG: RABEPRAZOLE SODIUM|DRUG: RABEPRAZOLE SODIUM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TDCS-potentiated Generalization of Cognitive Training in the Rehabilitation of Long COVID Symptoms
Status: WITHDRAWN
Conditions: Post-acute Sequelae SARS-CoV-2 Infection (PASC)
Interventions: OTHER: Active tDCS|OTHER: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of Nesiritide in the Management of Acute Diastolic Heart Failure
Status: TERMINATED
Conditions: Heart Failure|Cardiovascular Disease|Acute Heart Failure|Diastolic Heart Failure|Congestive Heart Failure|Heart Disease
Interventions: DRUG: Nesiritide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Single Agent GBR 1302 in Subjects With HER2 Positive Cancers
Status: TERMINATED
Conditions: HER2 Expressing Solid Tumours
Interventions: DRUG: CD3/HER2 bispecific monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine
Status: COMPLETED
Conditions: HPV Infections
Interventions: BIOLOGICAL: HPV Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Repeating Low Intensity Extracorporeal Shock Wave Treatment (LI-ESWT) for Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DEVICE: ARIES-ED device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of 141W94 in Combination With Other Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Amprenavir|DRUG: Nelfinavir mesylate|DRUG: Saquinavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of GSK1278863A in Healthy Subjects
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863A Placebo|DRUG: GSK1278863A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial
Status: COMPLETED
Conditions: Edema|Hypoproteinemia
Interventions: DRUG: Intravenous albumin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Anticoagulation Targets in ECLS (RATE)
Status: UNKNOWN
Conditions: Heart Failure|Respiratory Failure|Extracorporeal Membrane Oxygenation|Bleeding|Thrombosis
Interventions: DRUG: Heparin|DRUG: LMWH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EXL01 in Combination With Nivolumab for Advanced NSCLC Refractory to Immunotherapy.
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: EXL01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stapled Trans Anal Rectal Resection (STARR) for Outlet Obstruction: Functional and Morphological Outcome
Status: COMPLETED
Conditions: Surgery|Constipation
Interventions: PROCEDURE: STARR Operation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Post-Marketing Clinical Pharmacokinetics Study Of Gabapentin In Japanese Epileptic Subjects With Renal Impairment
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: Gabapentin|DRUG: Gabapentin|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin for Preventing Frailty in High-risk Older Adults
Status: COMPLETED
Conditions: Frailty
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Shorter Course Hormone Therapy and Radiation for High-risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Androgen deprivation therapy (ADT)|RADIATION: Brachytherapy|RADIATION: Hypofractionated pelvic External beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Age (Geriatric) and Kidney Function on the Safety, Efficacy and Pharmacokinetics of OctreoScan in Patients Who Have New or Recurrent Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Indium In-111 pentetreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache
Status: WITHDRAWN
Conditions: Headache
Interventions: DRUG: Ketorolac|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
Status: UNKNOWN
Conditions: Rotator Cuff Tear Arthropathy|Post Operative Pain
Interventions: PROCEDURE: supraescapular nerve radiofrequency|PROCEDURE: interescalenic braquial plexus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ranexa in Patients With Coronary Artery Disease and Painful Polyneuropathy
Status: TERMINATED
Conditions: Coronary Artery Disease|Pain|Peripheral Nervous System Diseases|Polyneuropathy
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Relative Bioavailability of New and Old ABSK-011 Capsules
Status: RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Sequence A ABSK-011|DRUG: Sequence B ABSK-011
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence (BE) Study Comparing Fluconazole 150mg Capsule Manufactured in China and in France
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Fluconazole 150mg Capsule Originator|DRUG: Fluconazole 150mg Capsule Localized Originator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Acute Oxytocin Administration Enhance Social Cognition in Individuals With Schizophrenia?
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Oxytocin|DRUG: Inactive placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effects of DA-9701 on Gastrointestinal Motility on Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: DA-9701 and placebo|DRUG: Placebo and DA-9701
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower-Limb Drainage Mapping in Pelvic Lymphadenectomy for Gynaecological Cancer
Status: COMPLETED
Conditions: Gynaecological Malignant Tumours With Indication of Pelvic Lymphadenectomy
Interventions: PROCEDURE: Lower-limb drainage isotopic intraoperative detection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: trastuzumab|DRUG: trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pakistan Short Interval mOPV1 Compared With Standard Interval mOPV1 and bOPV 1,3
Status: COMPLETED
Conditions: Polio
Interventions: DRUG: mOPV1|DRUG: bOPV 1,3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC
Status: RECRUITING
Conditions: Incidental Gallbladder Carcinoma|Biliary Tract Cancer
Interventions: DRUG: Gemcitabine|DRUG: Cisplatin|PROCEDURE: Oncologically radical margin-free (R0) resection|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical Trial
Status: COMPLETED
Conditions: Phythoterapy|Venipuncture Site Numbness|Antimicrobial|Analgesic
Interventions: OTHER: A. oleracea|OTHER: 70% alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Socio-psychological Factors Involved in the Hematopoietic Stem Cell Transplantation Process in People With Hemopathies
Status: COMPLETED
Conditions: Leukemia
Interventions: BEHAVIORAL: Personality and transactional factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation Of Clinical Performance of Self-adhering Flowable Composite vs Conventional Flowable Composite in Cervical Carious Lesions
Status: UNKNOWN
Conditions: Dental Caries
Interventions: COMBINATION_PRODUCT: Self-Adhesive Flowable Composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: ALK-Positive Large B-Cell Lymphoma|Diffuse Large B-Cell Lymphoma Activated B-Cell Type|Diffuse Large B-Cell Lymphoma Associated With Chronic Inflammation|Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type|Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|EBV-Positive Mucocutaneous Ulcer|HHV8-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements|High Grade B-Cell Lymphoma, Not Otherwise Specified|Intravascular Large B-Cell Lymphoma|Large B-Cell Lymphoma With 11q Aberration|Large B-Cell Lymphoma With IRF4 Rearrangement|Plasmablastic Lymphoma|Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System|Primary Effusion Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Burkitt Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Gray-Zone Lymphoma|Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Recurrent Lymphomatoid Granulomatosis|Recurrent Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type|Recurrent Primary Mediastinal Large B-Cell Lymphoma|Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Burkitt Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Gray-Zone Lymphoma|Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements|Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements|Refractory Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type|Refractory Primary Mediastinal Large B-Cell Lymphoma|Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Nivolumab|DRUG: Varlilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reinflation After Early Tourniquet Release in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: PROCEDURE: Reinflation after early tourniquet deflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Diaphragmatic Initiated Ventilatory Assist (DIVA) Trial
Status: RECRUITING
Conditions: Extubation Failure|Bronchopulmonary Dysplasia|Death
Interventions: DEVICE: NIV-NAVA|DEVICE: NS-NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab in Combination With Chemotherapy for Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Pembrolizumab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS Effects on GABA Concentration and Brain Functional Connectivity in Older Adults Of Working Age
Status: COMPLETED
Conditions: Healthy Older Adults
Interventions: DEVICE: tDCS|DEVICE: sham-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Postpartum Vaginal Estrogen for Breastfeeding Patients
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding|Postpartum Sexual Dysfunction|Vaginal Atrophy
Interventions: DRUG: Estradiol|DEVICE: Vaginal Moisturizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dreaming During Anesthesia and Anesthetic Depth in Elective Surgery Patients Under General Anesthesia
Status: UNKNOWN
Conditions: Dreaming|General Anesthesia
Interventions: DEVICE: deep anesthesia depth|DEVICE: light anesthesia depth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Single Rising Doses and Relative Bioavailability of BI 691751
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 691751|DRUG: BI 691751|DRUG: Placebo|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751|DRUG: BI 691751
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: VPA|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ustekinumab in Participants With Takayasu Arteritis (TAK)
Status: TERMINATED
Conditions: Takayasu Arteritis
Interventions: DRUG: Ustekinumab|OTHER: Placebo|DRUG: Glucorticoid Taper Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Iron-fortified Parenteral Nutrition in the Prevention and Treatment of Anemia in Premature Infants
Status: COMPLETED
Conditions: Premature Birth
Interventions: OTHER: iron sucrose-1|OTHER: iron sucrose-2|OTHER: iron sucrose-3|OTHER: iron sucrose-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multimodal Brain Imaging of the Neural Effects of Methylphenidate in Patients With ADHD
Status: RECRUITING
Conditions: ADHD - Combined Type
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Communication Training Intervention for Large B-Cell Lymphoma Providers
Status: RECRUITING
Conditions: Lymphoma, B-Cell|Lymphoma|Large-cell Lymphoma|Large B-cell Lymphoma|DLBCL - Diffuse Large B Cell Lymphoma|Mediastinal B-Cell Diffuse Large Cell Lymphoma
Interventions: BEHAVIORAL: Hematolo-GIST Training|BEHAVIORAL: Participants Appointment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Peripheral Neuromodulation on Vaginal Blood Flow
Status: COMPLETED
Conditions: Female Sexual Dysfunction|Spinal Cord Injuries
Interventions: DEVICE: Tibial e-stim|DEVICE: Genital e-stim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)
Status: COMPLETED
Conditions: Elevated Lp(a)
Interventions: DRUG: TA-8995|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Changes in Intra-myocardial Amino Acids During Use of Calafiore and Modified Del Nido Cardioplegia
Status: COMPLETED
Conditions: Myocardial Injury|Cardiac Surgery|Myocardial Protection
Interventions: OTHER: Cardioplegic solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blossom® Smart Expander Device for Tissue Expander/Implant-Based Breast Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Tissue Expansion|Implant Based Breast Reconstruction
Interventions: DEVICE: Blossom tissue expander|DEVICE: Standard tissue expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Contemporary Endovascular Therapies in Treatment of Acute Iliofemoral Deep Vein Thrombosis
Status: UNKNOWN
Conditions: Thrombolysis|Deep Vein Thrombosis
Interventions: DEVICE: Contemporary endovascular venous intervention by Zelante pharmacomechanical thrombolysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Plane Block and Spinal Anesthesia for Supine Percutaneous Nephrolithotomy
Status: UNKNOWN
Conditions: Incidence Conversion to General Anesthesia, Interleukin-6, Total Tramadol Consumption and Pain Score After Surgery
Interventions: PROCEDURE: Erector Spinae Plane Block|PROCEDURE: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individualized Telemedical Assistance for Lifestyle Modification in the Treatment of Obesity and Cardiometabolic Risk Prevention
Status: COMPLETED
Conditions: Obesity Type I and II
Interventions: DEVICE: Telemedic assistance with a technological system|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retention in Physically Demanding Jobs With Low Back Pain: A Randomised Controlled Trial (GoBack)
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: BEHAVIORAL: Occupational intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IMR Evaluation in Patients With Coronary Sinus Reducer Implantation (INROAD Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Angina Pectoris
Interventions: PROCEDURE: IMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ixazomib Plus Lenalidomide Plus Dexamethasone for Newly Diagnosed Myeloma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TriVascular European Union (EU) Abdominal Stent Graft Trial
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Implant of Ovation Abdominal Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Hypnotic Cognitive Therapy for Chronic Pain in SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries|Chronic Pain
Interventions: BEHAVIORAL: Hypnotic Cognitive Therapy (HYPNOCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TCR-Redirected T Cell Infusion to Prevent Hepatocellular Carcinoma Recurrence Post Liver Transplantation
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: TCR-T|BIOLOGICAL: No intervention and TCR-T (at crossover)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tranexamic Acid vs. Quixil - Reducing Blood Loss in Joint Replacement
Status: COMPLETED
Conditions: Hemorrhage|Arthroplasty, Replacement, Hip|Arthroplasty, Replacement, Knee
Interventions: DRUG: IV Tranexamic acid 10mg/kg pt body weight|DRUG: Quixil topical sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Endobiliary Radiofrequency Ablation for Malignant Biliary Obstruction Due to Perihilar Cholangiocarcinoma
Status: RECRUITING
Conditions: Perihilar Cholangiocarcinoma
Interventions: DEVICE: Endobiliary radiofrequency ablation (eRFA)|DEVICE: uncovered self-expanding metal stent (uSEMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare the Efficacy and Safety of Ziprasidone and Risperidone for the Treatment of Schizophrenia in Chinese Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF
Status: NOT_YET_RECRUITING
Conditions: Effectiveness of Isoamyl-2-cyanoacrylate With and Without Ethiodized Oil in Occluding Hydrosalpinx Prior to IVF
Interventions: DRUG: iso-amyl- 2-cyanoacrylate.|DRUG: iso-amyl- 2-cyanoacrylate mixed with Ethiodized oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Olfaction / Vision Interactions in Expert and Novice Populations
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Odor presentation (for participants' perception)|OTHER: Image presentation (for participants' perception)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: RituxiMab INDuction in Renal Transplantation
Status: UNKNOWN
Conditions: Function of Renal Transplant
Interventions: DRUG: Rituximab|DRUG: Tacrolimus|DRUG: Mycophenylate mofetil|DRUG: Hydrocortisone|DRUG: Prednisolone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Ischemic Apoplexy Syndrome Specificity and Acupuncture Intervention Research
Status: UNKNOWN
Conditions: Acute Ischemia
Interventions: OTHER: Acupuncture Treatment|OTHER: Regular Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes
Status: RECRUITING
Conditions: Glucose Intolerance After a Recent History of Gestational Diabetes
Interventions: DRUG: Semaglutide Pen Injector|DRUG: Semaglutide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Beta Blockade on Left Ventricular Remodeling and Function in Moderate to Severe Asymptomatic Aortic Regurgitation
Status: COMPLETED
Conditions: Aortic Valve Insufficiency
Interventions: DRUG: Metoprolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adjunctive Tianeptine in the Treatment of Bipolar Depression
Status: UNKNOWN
Conditions: Bipolar Disorder
Interventions: DRUG: tianeptine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Low Dose Tamoxifen in Women With Breast Intraepithelial Neoplasia - Long Term Follow-up
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Intraductal, Noninfiltrating|Recurrence, Local Neoplasm|Breast Neoplasms|Atypical Hyperplasia
Interventions: DRUG: Tamoxifen|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of ACYW135 Meningococcal Polysaccharide Vaccine Aged 2-50 Years Old
Status: UNKNOWN
Conditions: ACYW135 Meningococcal Polysaccharide Vaccine
Interventions: BIOLOGICAL: Tiantan Biology ACYW135 meningococcal polysaccharide vaccine|BIOLOGICAL: Hualan Biology ACYW135 meningococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact on Recurrence Risk of Adjuvant Lenvatinib for Patients With Hepatocellular Carcinoma And Microvascular Invasion (MVI) After Hepatectomy : A Random, Controlled, Stage III Clinical Trial.
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT