pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vincristine, Doxorubicin, Cyclophosphamide and Dexrazoxane (VACdxr) in High Risk Ewing's Sarcoma Patients
Status: TERMINATED
Conditions: Ewing's Sarcoma
Interventions: DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Dexrazoxane|BIOLOGICAL: ImmTher
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: LeucoPatch|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-AAT in Normal Adult Volunteers
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: ARO-AAT Injection|OTHER: Sterile Normal Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-Exposure Prophylaxis in YMSM
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: coformulated emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) as PrEP|DRUG: Placebo|BEHAVIORAL: Many Men, Many Voices (3MV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Large Artery Plaque Imaging Features in Predicting Inflammation and Cognition
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Impairment|Carotid Artery Plaque|Inflammation
Interventions: DRUG: Imaging with flutemetamol F 18 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of Two Regimens of Maintenance Therapy in Children With Crohn Disease
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: Infliximab with azathioprine (IIFX + AZA)|DRUG: Infliximab (IFX alone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet Administered CBT for Insomnia Comorbid With Chronic Pain
Status: COMPLETED
Conditions: Insomnia Due to Medical Condition|Chronic Pain
Interventions: BEHAVIORAL: Internet Cognitive Behavioral Therapy for insomnia (ICBT-i)|BEHAVIORAL: Internet Applied Relaxation Techniques (IART-i)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of BNX Sublingual Tablets Versus BNX Sublingual Film for Treatment of Opioid-Dependent Adults
Status: COMPLETED
Conditions: Opioid Dependence, on Agonist Therapy
Interventions: DRUG: BNX sublingual tablets|DRUG: BNX sublingual film|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of a Clinical Pharmacist in the Management of Type 2 Diabetic Patients in a Primary Medical Center in Jordan
Status: COMPLETED
Conditions: Pharmacist-Patient Relations
Interventions: OTHER: Collaborative approach of clinical pharmacist with physicians in a medical center
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Association Between Local Cerebral Oxygenation Monitoring and Postoperative Stroke in Carotid Endarterectomy
Status: NOT_YET_RECRUITING
Conditions: Carotid Endarterectomy|Cerebral Autoregulation
Interventions: OTHER: Cerebral Oxygenation index guided hemodynamics management|OTHER: routine hemodynamics management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treating COVID-19 With Hydroxychloroquine (TEACH)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine (HCQ)|DRUG: Placebo: Calcium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Changes in Inflammatory Response After Immunonutrition Compared to Standard Nutrition in Colorectal Cancer Tissue
Status: COMPLETED
Conditions: Colon Cancer|Nutrition Aspect of Cancer
Interventions: DIETARY_SUPPLEMENT: Immunonutrition|DIETARY_SUPPLEMENT: Standard Oral Nutritional Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of the Ophthalmic Pazufloxacin 0.6% for Bacterial Conjunctivitis, Compared to Gatifloxacin 0.3%.
Status: TERMINATED
Conditions: Conjunctivitis, Bacterial
Interventions: DRUG: Pazufloxacin|DRUG: Zymar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucagon Resistance in Patients With NAFLD
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis|Glucose Metabolism Disorders
Interventions: OTHER: glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Panretinal Photocoagulation During Vitrectomy for Diabetic Vitreous Hemorrhage
Status: UNKNOWN
Conditions: Diabetic Vitreous Hemorrhage
Interventions: PROCEDURE: laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
Status: COMPLETED
Conditions: Astrocytoma|Brain Cancer|Brain Metastases|Bladder Cancer|Breast Cancer|Cervical Cancer|Cholangiocarcinoma|Colorectal Cancer|Esophagus Cancer|Gastric Cancer|Head and Neck Cancer|Kidney Cancer|Liver Cancer|Lung Cancer|Melanoma|Ovarian Cancer|Pancreatic Cancer|Pleural Mesothelioma|Prostate Cancer|Sarcoma|Tongue Cancer|Thymic Carcinoma|Urinary Tract Cancer
Interventions: DRUG: QBS10072S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride in Molar-Incisor Hypomineralisation
Status: NOT_YET_RECRUITING
Conditions: Molar-Incisor Hypomineralisation
Interventions: OTHER: glass hybrid restorative system|OTHER: Fluoride varnish + Glass hybrid restorative system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise With Diet Induces Hormonal, Metabolic, and Psychological Changes
Status: COMPLETED
Conditions: Elderly|Hormones|Insulin Resistance|Depression
Interventions: OTHER: aerobic exercise and diet program|OTHER: diet program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Headache Disorders: A Clinical Trial Screening for Prognostic Patient Characteristics
Status: TERMINATED
Conditions: Headache
Interventions: PROCEDURE: Usual Care provided by a medical doctor (GP or Neurologist)|PROCEDURE: Usual care plus Physio-/ Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases
Status: NOT_YET_RECRUITING
Conditions: Cancer Metastatic
Interventions: RADIATION: Standard Conventional Radiotherapy|RADIATION: Stereotactic Body Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curvafix® Intramedullary System for Fixation of Pelvic and Acetabular Fractures, A Post Market Evaluation
Status: RECRUITING
Conditions: Pelvic Ring Fracture|Acetabular Fracture|Pelvic Fracture|Pelvic Fracture Acetabulum
Interventions: DEVICE: IM Implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bidirectional Text Messaging for Measurement and Motivation of Medication Adherence in Hypertension, a Pilot Study
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Electronic Pill Bottle|BEHAVIORAL: Bidirectional Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ketone Administration During Inactivity and Retraining
Status: UNKNOWN
Conditions: Exercise|Healthy Male/Female Subjects
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Medium Chain Triglyceride (MCT) oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphocytic Leukemia, Chronic
Interventions: DRUG: Chlorambucil|DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Romiplostim for Thrombocytopenia Induced by Lomustine at First Progression of MGMT Promoter-meth Glioblastoma
Status: WITHDRAWN
Conditions: First Progression of MGMT Promoter-methylated Glioblastoma
Interventions: DRUG: Lomustine|DRUG: Romiplostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Peripheral Nerve Stimulation (PNS) to Treat Chronic Post-surgical Pain (CPSP) After Knee Surgery
Status: WITHDRAWN
Conditions: Injury; Nerve, Peripheral, Multiple|Chronic Post-Procedural Pain|Total Knee Arthroplasty|Surgery|Knee Injuries|Knee Pain Chronic|Postoperative Pain|Chronic Postoperative Pain
Interventions: DEVICE: SPRINT® Peripheral Nerve Stimulation (PNS) System (510k Cleared)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Medium-Chain Triglycerides on Chylomicron Secretion and Expression of Genes That Regulate Intestinal Lipid Metabolism in Men With Dyslipidemia Associated With the Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: OTHER: Medium-chain triglycerides|OTHER: Corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: (Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy
Status: COMPLETED
Conditions: Fatigue|Sleep Disorders|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: Valeriana officinalis extract|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Triple-blinded, Randomised, Placebo-controlled Trial to Examine the Efficacy and Safety of ViNeuro in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: ViNeuro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of IMC-1121B (Ramucirumab) in Participants With Liver Cancer Who Have Not Previously Been Treated With Chemotherapy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Ramucirumab (IMC-1121B)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Nutrition Based on the Glycemic Response: Effect of Diet and Intestinal Microbiota
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Pre Diabetes
Interventions: DIETARY_SUPPLEMENT: A package containing a mix of functional foods|OTHER: Placebo ingredient group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Medical Treatment With SOM230 LAR in Patients With Primary Inoperable Thymoma and/or With Local Recurrent Thymoma to Reduce Tumor Size
Status: COMPLETED
Conditions: Primary Inoperable Thymoma|Local Recurrent Thymoma
Interventions: DRUG: SOM230 LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Light on Sleep Quality and Physiological Parameters in Individuals in Intensive Care Unit
Status: COMPLETED
Conditions: Sleep|Light
Interventions: OTHER: Comparison of the personal characteristics of the experimental and control groups|OTHER: Light applied experimental group, control group treated with standard intensive care lighting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients With Motor Fluctuations
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Placebo|DRUG: PF-06649751 low dose (1 mg QD)|DRUG: PF-06649751 middle dose 1 (3 mg QD)|DRUG: PF-06649751 middle dose 2 (7 mg QD)|DRUG: PF-06649751 high dose (15 mg QD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Immunogenicity, Safety and Reactogenicity of the Combined DTPa-IPV Vaccine in Healthy Infants
Status: COMPLETED
Conditions: Tetanus|Acellular Pertussis|Diphtheria
Interventions: BIOLOGICAL: DTPa-IPV|BIOLOGICAL: DTPa|BIOLOGICAL: IMOVAX Polio®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: "QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Pebrolizumab + QUADSHOT Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Tubular Coaxial Nickel-titanium and Copper Nickel-titanium Orthodontic Aligning Archwires
Status: COMPLETED
Conditions: Aligning Archwires
Interventions: OTHER: aligning archwires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Stage Study of Combination of Chemotherapy, SHR-1210 and/or Decitabine for Relapsed/Refractory PMBCLs
Status: UNKNOWN
Conditions: Primary Mediastinal Large B-cell Lymphoma
Interventions: DRUG: Decitabine|DRUG: GVD chemotherapy|DRUG: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Importance of the Number of Incisions in the Effectiveness of Dry Needling
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Dose of five-incisions dry needling technique|OTHER: Dose of ten-incisions dry needling technique|OTHER: Dose of fifteen-incisions dry needling technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Maintenance of Sustained Remission of axSpA With CZP Compared to Placebo
Status: COMPLETED
Conditions: Axial Spondyloarthrithis|Ankylosing Spondylitis
Interventions: BIOLOGICAL: Certolizumab Pegol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of BITS7201A in Healthy Volunteers and Participants With Mild Atopic Asthma
Status: COMPLETED
Conditions: Mild Atopic Asthma
Interventions: DRUG: BITS7201A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SDF Effectiveness on Arresting Caries in Children
Status: RECRUITING
Conditions: Dental Caries in Children
Interventions: DRUG: Silver Diamine Fluoride (SDF)|OTHER: Glass Ionomer Restoration (GI)|OTHER: Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: WCC# 59 Hyperthermic Intraperitoneal Chemotherapy Utilizing Carboplatin in First Recurrence Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Carcinoma
Interventions: DRUG: Hyperthermic intraperitoneal chemotherapy with Carboplatin|OTHER: Isotonic saline (perfusate)|PROCEDURE: Surgery|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JT001 (VV116) for the Early Treatment of COVID-19
Status: TERMINATED
Conditions: Mild to Moderate COVID-19
Interventions: DRUG: JT001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Using a Smartphone Health Application in the Improvement of Cardiovascular Disease Risk Factors
Status: NOT_YET_RECRUITING
Conditions: Hypercholesterolemia|Obesity|Diabetes Mellitus|Hypertension
Interventions: OTHER: smartphone health application (Opulse)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Acute Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelofibrosis|MDS|Refractory Anemia|Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Non-Hodgkin's Lymphoma|Leukemia|Lymphoma|Multiple Myeloma|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Challenge Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella: Phase IIb
Status: TERMINATED
Conditions: Shigella
Interventions: BIOLOGICAL: CVD 1208S, Challenge strain of wild-type Shigella flexneri 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Tecfidera® in Radiologically Isolated Syndrome (RIS)
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: Tecfidera|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ATN-224 and Bortezomib in Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: ATN-224 + bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Lung Biopsy Using Cone Beam CT With Virtual Guidance: a Randomized Control Trial
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Percutaneous lung biopsy using conventional MDCT|PROCEDURE: Percutaneous lung biopsy CBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of MEDITOXIN® in Female Patients With Idiopathic Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Meditoxin|DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Endobronchial Ultrasound Guided Transbronchial Needle Aspiration (EBUS-TBNA) for Mediastinal Re-staging of Non-small Cell Lung Cancer(NSCLC)
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: EBUS-TBNA, integrated PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: RIBAJUSTE Clinical Trial Investigating the Efficacy and Safety of Dose Adaptation of Ribavirin
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peg-interferon alpha 2a and ribavin|DRUG: ribavirin with adaptation dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Feasibility of a Metaverse-based Blended Online Intervention to Prevent Employees' Depression
Status: NOT_YET_RECRUITING
Conditions: Depression and Suicide
Interventions: BEHAVIORAL: metaverse-based blended online intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Clofarabine and Cytarabine for Older Patients With Relapsed or Refractory Acute Myelogenous Leukemia (AML)(CLASSIC I)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: clofarabine (IV formulation)|DRUG: placebo|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic Study of Three Abatacept Products in Male Normal Healthy Volunteers by the Subcutaneous Route
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Test Product|DRUG: Reference product|DRUG: Reference Medicinal Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Testing a New Therapy for Trichotillomania
Status: COMPLETED
Conditions: Trichotillomania
Interventions: BEHAVIORAL: Acceptance enhanced behavior therapy (AEBT)|BEHAVIORAL: Psychoeducation and supportive therapy (PST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Osteopathic Manual Therapy On Arterial Circulation In Patients With Peripheral Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Osteopathy in Diseases Classified Elsewhere
Interventions: OTHER: Osteopathic Manual Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Loss of Chromosome 17p
Interventions: DRUG: Ibrutinib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Chagas Blood Screening and Confirmatory Assays
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: ABBOTT PRISM Chagas Assay and Chagas Confirmatory Assay|DEVICE: ABBOTT PRISM Chagas Assay and Chagas Confirmatory Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase 2 Single-Masked, Randomized Study of Latanoprost PPDS in Ocular Hypertension or Open-Angle Glaucoma
Status: COMPLETED
Conditions: Ocular Hypertension|Open-Angle Glaucoma
Interventions: DRUG: Latanoprost Punctal Plug Delivery System (L-PPDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De Novo Lipogenesis and Insulin Sensitivity in Obese
Status: COMPLETED
Conditions: Insulin Resistance|Obesity
Interventions: BEHAVIORAL: Fasting/refeeding|BEHAVIORAL: Fasting/refeeding|BEHAVIORAL: Ketogenic diet/ fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: BE Study of Bilayer Combination of Gemigliptin/Rosuvastatin 50/20mg in Comparison to Monolayer Combination.
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Dyslipidemias
Interventions: DRUG: Monolayer group|DRUG: Bilayer group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
Status: COMPLETED
Conditions: Refractive Errors|Myopia|Hyperopia
Interventions: DEVICE: Lehfilcon A contact lens|DEVICE: Comfilcon A contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Multi-center, Single Arm Study Evaluating the Express™ Renal Premounted Stent System in the Treatment of Atherosclerotic Lesions in the Aortorenal Ostium.
Status: COMPLETED
Conditions: Atherosclerotic Lesions in the Aortorenal Ostium
Interventions: DEVICE: Express™ Renal Premounted Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Analgesia in Radiofrequency Ablation Therapy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: ESPB group|DRUG: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Capecitabine in Metastatic Non-clear Cell Renal Cell Carcinoma (RCC) Patients
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-based Diabetic Foot Care Training Prepared With the Health Belief Model for Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Training on web-based diabetic foot care based on the Health Belief Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study Evaluating the Efficacy and Safety of AbGn-168H in Patients With Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: BIOLOGICAL: AbGn-168H
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Treatment of Veterans With PTSD and Comorbid OUD
Status: TERMINATED
Conditions: Post-Traumatic Stress Disorders|Opiate Use Disorder
Interventions: DRUG: Buprenorphine|BEHAVIORAL: Cognitive Processing Therapy (CPT)|BEHAVIORAL: Individual Drug Counseling (IDC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Sensitization and Habituation in a Model of Experimentally-induced Insomnia Symptoms
Status: COMPLETED
Conditions: Sleep Control Condition|Insomnia Symptoms Induction Condition
Interventions: BEHAVIORAL: Insomnia symptom induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of 24-hour Holter Monitoring Versus 14-day Continuous ECG Patch Monitoring EZYPRO
Status: UNKNOWN
Conditions: Atrial Fibrillation|Arrhythmias, Cardiac
Interventions: DEVICE: EZYPRO®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypofractionated Intensity-Modulated Radiation Therapy With Temozolomide and Bevacizumab for Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Bevacizumab|DRUG: Temozolomide|RADIATION: RT (Radiation Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying TAK-243 in Patients With Advanced Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: UAE Inhibitor TAK-243
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Focused Extracorporeal Shock Wave Therapy (ESWT) Versus Traditional Physiotherapy in the Treatment of Trigger Finger
Status: WITHDRAWN
Conditions: Trigger Finger|Stenosing Tenosynovitis
Interventions: DEVICE: Focused Extracorporeal Shock Wave Therapy (ESWT)|DEVICE: physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Desmopressin for Improving Nocturnal Enuresis in Patients After Radical Cystectomy With Bladder Reconstruction
Status: UNKNOWN
Conditions: Nocturnal Enuresis
Interventions: DRUG: Desmopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Nasacort in Chronic Non Allergic and Non Infectious Rhinitis in Adults
Status: TERMINATED
Conditions: Rhinitis
Interventions: DRUG: triamcinolone acetonide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Ultrasound Guided Quadratus Lumborum Versus Lumbar Epidural Block on Postoperative Analgesia, and Inflammatory Response in Abdominal Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Inflammatory Response
Interventions: OTHER: Ultrasound quadratus lumborum block with bupivacaine 25%|OTHER: lumbar epideural block with bupivacaine 25%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Two Rifaximin Tablets in Patients With Travelers' Diarrhea.
Status: TERMINATED
Conditions: Travelers' Diarrhea
Interventions: DRUG: Rifaximin (Sandoz GmbH) tablet|DRUG: Rifaximin (Xifaxan)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: Glucovance (metformin HCl/glyburide)|DRUG: metformin HCl|DRUG: glyburide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety of Adipose-Derived Stem Cell Stromal Vascular Fraction
Status: UNKNOWN
Conditions: Abnormally Healing Wounds|Scars|Soft Tissue Defects
Interventions: BIOLOGICAL: ADSC-SVF-002
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Healing of Apical Periodontitis in Periodontally Diseased and Healthy Patients.
Status: COMPLETED
Conditions: Apical Periodontitis
Interventions: PROCEDURE: Intra orifice barrier|PROCEDURE: Base|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prednisone and Acupuncture for the Treatment of Facial Neuritis: a Multiple Center, CER in China
Status: UNKNOWN
Conditions: Bell's Palsy
Interventions: DRUG: Prednisolone|DEVICE: acupuncture|OTHER: other treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS
Status: COMPLETED
Conditions: COVID-19|ARDS
Interventions: BIOLOGICAL: ExoFlo|OTHER: Intravenous normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer
Status: TERMINATED
Conditions: Metastatic Kidney Carcinoma|Recurrent Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v7|Stage IV Renal Cell Cancer AJCC v7
Interventions: DRUG: Akt Inhibitor MK2206|DRUG: Everolimus|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Protocol of Intramyocardial Injection of Autologous Bone Marrow Stem Cells for Refractory Angina
Status: COMPLETED
Conditions: Refractory Angina
Interventions: PROCEDURE: Local sedation|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Minithoracotomy|BIOLOGICAL: Autologous bone marrow mononuclear cells infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Impact of Clopidogrel (Plavix®) on Bleeding Associated With Punch Biopsies in Healthy Volunteers
Status: COMPLETED
Conditions: Haemostasis|Healthy
Interventions: DRUG: clopidogrel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tetrathiomolybdate in the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Tetrathiomolybdate (TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of NOL Index Intraoperative Guided Remifentanil Analgesia
Status: RECRUITING
Conditions: Abdominal Surgery
Interventions: DEVICE: Bispectral index|DEVICE: Bispectral index + NOL index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Omega-3 Long Chain Polyunsaturated Fatty Acid (LCPUFA) Supplementation in Very Low Birth Weight Infants for The Prevention Retinopathy of Prematurity
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Omegaven|DIETARY_SUPPLEMENT: Standard lipids (primarily omega-6 fatty acids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: placebo(distilled water|DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Analgesic Efficacy Supra-scapular Nerve RF After Breast Surgery
Status: COMPLETED
Conditions: Chronic Pain Syndrome
Interventions: PROCEDURE: suprascapular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Study To Characterize The Pharmacokinetics And The Effects Of Food On Oxycodone In Healthy Volunteers
Status: COMPLETED
Conditions: Analgesia|Acute Pain|Chronic Pain|Narcotic Abuse|Opioid-related Disorders
Interventions: DRUG: oxycodone hydrochloride|DRUG: oxycodone hydrochloride|DRUG: oxycodone hydrochloride|DRUG: oxycodone hydrochloride|DRUG: marketed oxycodone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acquisition of Objective Data During Transapical Neochordae Implantation
Status: WITHDRAWN
Conditions: Mitral Valve Insufficiency|Mitral Regurgitation
Interventions: PROCEDURE: Chordal tension measurement|OTHER: Cardiac Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuroendocrine Response to Oral Alcohol Administration
Status: COMPLETED
Conditions: Alcohol Abuse
Interventions: OTHER: Alcoholic Beverage|OTHER: Non-Alcoholic Beverage|DRUG: Ethanol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults.
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: DRUG: Ad26.COV2.S (VAC31518, JNJ-78436735) Vaccine, SARS-CoV-2 rS (CovovaxTM), BNT162b2 (Pfizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine
Status: RECRUITING
Conditions: Diphtheria|Tetanus|Pertussis
Interventions: BIOLOGICAL: DTacP (one-dose booster)|BIOLOGICAL: DTacP (three-dose primary vaccination)|BIOLOGICAL: DT (one-dose booster)|BIOLOGICAL: DTaP (one-dose booster)|BIOLOGICAL: PENTAXIM (one-dose booster)|BIOLOGICAL: DTaP (three-dose primary vaccination)|BIOLOGICAL: PENTAXIM (three-dose primary vaccination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Real World Study to Evaluate Effectiveness of Avastin (Bevacizumab) for First Line Treatment of Patients With Metastatic Colorectal Cancer and Known KRAS Status
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Anti-EGFR-Containing Regimen|DRUG: Bevacizumab-containing regimen|DRUG: Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TENS for Suction Evacuation for Termination of 1st Trimester Pregnancies
Status: UNKNOWN
Conditions: Pregnancy, Abdominal|Termination of Pregnancy|Pain, Nerve
Interventions: DEVICE: Transcutaneous nerve stimulation (TENS)|DEVICE: Placebo Transcutaneous nerve stimulation (TENS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endotracheal Tube (ETT) 180: Stylet-loaded Endotracheal Tube Rotation Before Insertion
Status: RECRUITING
Conditions: Anesthesia, Endotracheal
Interventions: DEVICE: Direct Laryngoscope (DL)|DEVICE: Video laryngoscope (VL)|PROCEDURE: Endotracheal Tube (ETT) 180
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Efficacy, Safety, and Tolerability of ADL5747 in Participants With Postherpetic Neuralgia
Status: TERMINATED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: ADL5747|DRUG: Placebo|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprascapular Nerve Block Efficacy for Shoulder Surgery
Status: UNKNOWN
Conditions: Shoulder Pain|Postoperative Pain|Rotator Cuff Tears|Anesthesia|Anesthesia, Local
Interventions: PROCEDURE: Suprascapular nerve block|PROCEDURE: Interscalene Nerve Block|PROCEDURE: Arthroscopic rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improved Bowel Preparation Method for Colonoscopy Based on Different Risk Stratification
Status: COMPLETED
Conditions: Bowel Preparation Before Colonoscopy
Interventions: DRUG: PEG|DRUG: PEG+lactulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Ambient Lighting During Colonoscopy and Its Effect on Adenoma Detection Rate and Eye Fatigue
Status: COMPLETED
Conditions: Colorectal Cancer Screening|Colon Adenomatous Polyp
Interventions: OTHER: Ambient lighting|OTHER: Low lighting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sleep and Tolerability Study: Comparing the Effects of Adderall XR and Focalin XR
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Dexmethylphenidate|DRUG: Mixed Amphetamine Salts, ER|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Condom Performance in a Longitudinal Enhanced Assessment of User Experiences
Status: COMPLETED
Conditions: HIV
Interventions: DEVICE: 5 Fitted Condoms, 5 Thin Condoms, 5 Standard Condoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TTAC-0001 and Pembrolizumab Combination phase1b Trial in Recurrent Glioblastoma
Status: UNKNOWN
Conditions: Recurrent Glioblastoma
Interventions: DRUG: TTAC-0001 and pembrolizumab combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diesel Exhaust Induces Glucocorticoid Resistance
Status: RECRUITING
Conditions: Exposure to Pollution|Glucocorticoid Resistance
Interventions: OTHER: Placebo|DRUG: Budesonide|OTHER: Filtered Air|OTHER: Diesel Exhaust
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD
Status: RECRUITING
Conditions: COPD|COPD Exacerbation|COPD Bronchitis|Airway Disease|Immune System Disorder
Interventions: BIOLOGICAL: Tezepelumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure
Status: TERMINATED
Conditions: Cancer of the Bone|Limb Salvage
Interventions: DRUG: Tranexamic Acid|OTHER: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myocardial Infarction|Acute Coronary Syndrome
Interventions: DIAGNOSTIC_TEST: high-sensitivity cardiac troponin testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: L-carnitine for Reducing Cardio-metabolic Risk in Patients With Obstructive Sleep Apnea
Status: WITHDRAWN
Conditions: Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: L-carnitine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mycophenolate Mofetil (CellCept) in Lung Transplant Recipients
Status: COMPLETED
Conditions: Lung Transplantation
Interventions: DRUG: mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma in Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: platelet rich plasma|DRUG: MethylPREDNISolone 40 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Vagal Nerve Stimulation on Hemodynamics Parameters
Status: UNKNOWN
Conditions: Hypertension
Interventions: DEVICE: transcutaneous vagal nerve stimulation on|DEVICE: transcutaneous vagal nerve stimulation off
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE