pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy Study of ATGC-100 for the Treatment of Moderate to Severe Glabellar Lines in Adult Subjects
Status: COMPLETED
Conditions: Moderate to Severe Glabellar Lines
Interventions: BIOLOGICAL: ATGC-100|BIOLOGICAL: Botox®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab, Infusional Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan (A-FOLFOXIRI) Compared With Bevacizumab, Infusional Fluorouracil, Leucovorin, and Irinotecan/Oxaliplatin (A-FOLFIRI/FOLFOX) as First-line Treatment for Metastatic Right-sided Colon Cancer
Status: UNKNOWN
Conditions: Unresectable Metastatic Right-sided Colon Cancer Starting First-line Combination Chemotherapy|Unresectable Metastatic Right-sided Colon Cancer, Stage IV
Interventions: DRUG: A-FOLFOXIRI|DRUG: Arm II (A-FOLFOX/A-FOLFIRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 10 Weeks of Lifestyle Coaching on Cardiometabolic Risk Factors, Workability and Subjective Wellbeing
Status: UNKNOWN
Conditions: Work Related Stress|Metabolic Syndrome|Lipid Metabolism Disorders|Lifestyle Risk Reduction|Burnout
Interventions: BEHAVIORAL: Individual coaching|BEHAVIORAL: Group coaching|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Movement in the Non-use of the Affected Upper Extremity in Children Hemiparesis: Mirror Therapy and Action-observation
Status: UNKNOWN
Conditions: Hemiplegia, Infantile
Interventions: OTHER: Mirror therapy and action-observation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DRUG: BMS-919373|DRUG: Placebo (Matching with BMS-919373)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: 24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Saxagliptin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Local Infiltration Anesthesia in a Hip Arthroplasty Fast Track Program.
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: DRUG: 100cc of 2% ropivacaine|DRUG: Saline Solution|DRUG: Adrenaline 10mcg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Ruxolitinib in Colorectal Cancer Patients
Status: TERMINATED
Conditions: CRC (Colorectal Cancer)
Interventions: DRUG: Ruxolitinib|DRUG: Regorafenib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Manual Therapy and Exercise in the Treatment of Ankle Sprains
Status: COMPLETED
Conditions: Ankle Sprains
Interventions: PROCEDURE: Experimental (proprioception exercises, muscle strengthening, joint mobilization)|PROCEDURE: Control (proprioception exercises, muscle strengthening)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Parenchyma Resection of Cirrhotic Liver by the Clamp Crushing Technique and the Ultrasonic Dissector
Status: TERMINATED
Conditions: Liver Cirrhosis|Liver Neoplasms|Carcinoma, Hepatocellular
Interventions: DEVICE: clamp crushing technique|DEVICE: ultrasonic dissector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose-Finding Study of the Second Mitochondrial Activator of Caspases (SMAC) Mimetic Debio 1143 When Given in Combination With Avelumab to Participants With Advanced Solid Malignancies and to Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Platinum-Based Therapy
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Neoplasms
Interventions: DRUG: Debio 1143|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral, Genetic, and Epigenetic Implications of Dietary Supplementation With Alpha-linolenic Acid in Humans
Status: COMPLETED
Conditions: Effect of Fatty Acids on Memory Performance of Toddlers
Interventions: DIETARY_SUPPLEMENT: Flaxseed oil|DIETARY_SUPPLEMENT: corn oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Effect of a Suturing Technique on the Gingival Tissues Around Dental Implants
Status: COMPLETED
Conditions: Edentulous Jaw|Missing Teeth|Gingival Diseases
Interventions: PROCEDURE: Choukroun's technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Butyrate Enemas on Postoperative Intestinal Mobility Disorders in Hirschsprung's Disease
Status: UNKNOWN
Conditions: Hirschsprung's Disease
Interventions: DRUG: butyrate enemas + routine management|OTHER: routine management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Versus Conventional Impression CAD\CAM Constructed 4- Implant Supported Mandibular Overdenture Base
Status: COMPLETED
Conditions: Implant Complication
Interventions: OTHER: conventional impression group|OTHER: digital impression group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DRUG: (+)-Epicatechin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Induction and Maintenance Avelumab Plus R-CHOP in Patients With Diffuse DLBCL: The AvR-CHOP Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphomas Non-Hodgkin's B-Cell
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Benefit of Repairing the Deltoid Ligament in Unstable Ankle Fractures
Status: NOT_YET_RECRUITING
Conditions: Ankle Fractures|Deltoid Ligament; Sprain (Strain) (Ankle)
Interventions: PROCEDURE: Additional deep deltoid ligament suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Balapiravir in Patients With Dengue Virus Infection
Status: COMPLETED
Conditions: Dengue
Interventions: DRUG: balapiravir [RO4588161]|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 6 Weeks of Whole-body Vibration in Treatment of Postnatal Constipation
Status: COMPLETED
Conditions: Constipation
Interventions: COMBINATION_PRODUCT: Whole Body Vibration|OTHER: pelvic floor exercises and static abdominal exercises in addition to diet instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of a Gluten Free Diet In Patients With Schizophrenia Who Are Gliadin-Positive
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Gluten Free Flour|OTHER: Wheat Flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BEA 2180 BR in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BEA 2180 BR|DRUG: Placebo|DEVICE: Respimat® A 4|DRUG: Methacholine Chloride|DRUG: Spiriva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cervical Pessary vs Vaginal Progesterone in Preventing Preterm Birth Among Women Presenting With Short Cervix: An Open-label Randomized Controlled Trial
Status: UNKNOWN
Conditions: Preterm Birth|Short Cervix
Interventions: DEVICE: Pessary|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Effects of Repetitive TMS in Chronic Neuropathic Pain in People With SCI
Status: WITHDRAWN
Conditions: Spinal Cord Injuries|Neuralgia|Chronic Pain
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-Masked Study of Photrex (Rostaporfin) Photodynamic Therapy in the Treatment of Age-Related Macular Degeneration
Status: UNKNOWN
Conditions: Macular Degeneration
Interventions: DRUG: Photrex (rostaporfin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for the Development of a Diagnostic Score to Differentiate Myeloproliferative Neoplasms.
Status: RECRUITING
Conditions: Myeloproliferative Disorder|Essential Thrombocythemia|Primary Myelofibrosis, Prefibrotic Stage|Primary Myelofibrosis, Fibrotic Stage
Interventions: DIAGNOSTIC_TEST: Non-invasive diagnosis score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Study for Cognitive Deficits in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK-0777|DRUG: MK-0777|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Self-efficAcy Intervention to reDuce Injecting Risk behAviour and hePatitis c reinfecTion Rates
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BEHAVIORAL: Volitional Help Sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Peripheral Prism Glasses for Hemianopia
Status: COMPLETED
Conditions: Homonymous Hemianopia
Interventions: DEVICE: High power (57 prism diopter) peripheral prism glasses|DEVICE: Low power sham peripheral prism glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Concentration and Recovery After Carotid Endarterectomy
Status: COMPLETED
Conditions: Hypoxia-Ischemia, Brain|Ischemia, Vertebral Artery|Artery Stenosis, Carotid
Interventions: PROCEDURE: Oxygen concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Sensitivity Comparison of Follow-up MRI Between Acute Cerebral and Cerebellar Cortical Microinfarctions ( CMI )Microinfarctions
Status: RECRUITING
Conditions: Acute Cerebral and Cerebellar Cortical Microinfarctions (CMI)
Interventions: OTHER: None, purely observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analysis of the Effectiveness of the Use of Glycine Powder and Angled Implant Brush in Oral Hygiene Maintenance in Patients Reinstated With Columbus Bridge ProtocolTM
Status: RECRUITING
Conditions: Plaque, Dental
Interventions: PROCEDURE: Glycine Perio Flow|BEHAVIORAL: Angled Toothbrush|PROCEDURE: Standard Professional Oral Hygiene|BEHAVIORAL: Standard Domiciliary Oral Hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy
Status: COMPLETED
Conditions: Metastatic Biliary Tract Carcinoma
Interventions: DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pulse Field Ablation on Atrial Mechanics in Catheter Ablation of Paroxysmal Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation Paroxysmal
Interventions: PROCEDURE: Pulmonary vein isolation by pulse field ablation|PROCEDURE: Pulmonary vein isolation by cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in Chinese Adults Who Are Above a Healthy Weight Range (OASIS 3)
Status: RECRUITING
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Semaglutide Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Immune Responses of GSK Biologicals' HPV Vaccine Following Manufacturing Process Adaptation.
Status: COMPLETED
Conditions: Infections, Papillomavirus|Papillomavirus Vaccines
Interventions: BIOLOGICAL: Cervarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Phase 3 Study to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan(BR-A-657∙K) 30mg Compared to Placebo in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Placebo|DRUG: Valsartan|DRUG: Fimasartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The FLASH Study: A Study of Roflumilast Versus Placebo in Patients With Asthma (BY217/M2-023)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Synovium Brushing to Augmented Microfracture for Improved Cartilage Repair
Status: COMPLETED
Conditions: Defect of Articular Cartilage|Cartilage Injury|Osteoarthritis, Knee
Interventions: DEVICE: Arthroscopic synovial brushing|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Tauopathies|Neurodegenerative Diseases|Neurocognitive Disorders|Mental Disorders|Mild Cognitive Impairment
Interventions: DRUG: XPro1595|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Hypothermia in Endovascular Stroke Thrombectomy
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute Ischemic
Interventions: PROCEDURE: hypothermia|PROCEDURE: thrombectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic (PK) Evaluation of Bemotrizinol (6%) in a Sunscreen Maximum Usage Trial
Status: COMPLETED
Conditions: Pharmacokinetics|Absorption; Chemicals
Interventions: DRUG: Bemotrizinol (6%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Investigational Immuno-Therapy Study of Experimental Medication BMS-986277 Given Alone and in Combination With Nivolumab in Epithelial Cancers
Status: TERMINATED
Conditions: Cancer
Interventions: BIOLOGICAL: BMS-986277|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nivolumab-Ipilimumab and cfDNA in Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: cfDNA blood test|DRUG: Nivolumab|DRUG: Ipilimumab|COMBINATION_PRODUCT: Platinum-based Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion
Status: NO_LONGER_AVAILABLE
Conditions: Infection, Soft Tissue|Infection, Wound|Cellulitis|Diabetic Foot Ulcer
Interventions: DRUG: Cefazolin|DEVICE: Silberg Tissue Preparation System
Study Type: EXPANDED_ACCESS
Clinical trial: Reducing Acute Upper Gastrointestinal Side-Effects of Thoracic Irradiation
Status: RECRUITING
Conditions: Radiation Esophagitis
Interventions: DRUG: Sucralfate|OTHER: Usual Care|OTHER: One consent|OTHER: Two consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Methyl Aminolaevulinate Photodynamic Therapy With and Without Er:YAG Laser in Bowen's Disease
Status: COMPLETED
Conditions: Bowen's Disease
Interventions: DRUG: Er:YAG AFL-PDT|DRUG: MAL-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pitavastatin in Elderly Patients With Primary Hypercholesterolemia or Combined Dyslipidemia
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemias
Interventions: DRUG: Pitavastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BGB 3111 in Combination With Obinutuzumab in Participants With B-Cell Lymphoid Malignancies
Status: COMPLETED
Conditions: B-cell Lymphoid Malignancies
Interventions: DRUG: Zanubrutinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological Diseases
Status: COMPLETED
Conditions: Sialorrhea
Interventions: DRUG: Botulinum toxin A (BoNT-A) 50U|DRUG: Botulinum toxin A (BoNT-A) 100U|DRUG: Botulinum toxin A (BoNT-A) 200U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral LBH589 in Adult Participants With Refractory/Resistant Cutaneous T-Cell Lymphoma (CTCL)
Status: TERMINATED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: DRUG: Panobinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Infusion Carfilzomib on a Weekly Schedule in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms|Malignancies
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: dapagliflozin|DRUG: placebo|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Stair Step Study"
Status: COMPLETED
Conditions: Ovulation Disorder
Interventions: DRUG: Medroxyprogesterone Acetate 10 MG|OTHER: Stair step protocol without Medroxyprogesterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DePuy Synthes Variable Angle LCP Patella Plating System Study
Status: NOT_YET_RECRUITING
Conditions: Trauma|Patella Fracture|Knee Cap|Knee Cap Injury|Knee Discomfort|Knee Deformity
Interventions: DEVICE: Variable Angle LCP Patella Plating System|DEVICE: Traditional Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: D-MPH in the Treatment of Fatigue and Neurobehavioral Function Related to Chemotherapy in Adult Cancer Patients
Status: COMPLETED
Conditions: Fatigue|Neoplasms
Interventions: DRUG: dexmethylphenidate(d-mph)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dextromethorphan syrup - low dose|DRUG: Dextromethorphan syrup - high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer|Deep Diabetic Foot Ulcer
Interventions: COMBINATION_PRODUCT: Dermacell|COMBINATION_PRODUCT: Integra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Oxaliplatin/5-FU in Patients With Recurrent or Metastatic Head and Neck Cancer
Status: TERMINATED
Conditions: Cancer of the Head and Neck|Neoplasms, Head and Neck
Interventions: DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17
Status: TERMINATED
Conditions: Decompensated Cirrhosis
Interventions: COMBINATION_PRODUCT: Methacetin Breath Test|DRUG: Emricasan|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Trial of Vistusertib（AZD2014） Single Agent in TSC1or 2 Null or TSC 1/2 Mutation Solid Cancer Patients Refractory to Standard Chemotherapy
Status: WITHDRAWN
Conditions: Solid Tumor
Interventions: DRUG: Vistusertib(AZD2014)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Intraoperative Clonidine Reduce Post Operative Agitation in Children?
Status: COMPLETED
Conditions: Psychomotor Agitation
Interventions: DRUG: Clonidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Multicentre, Pilot Study to Evaluate the Safety and the Feasibility of Planning and Execution of Surgical Revascularization in Patients With Complex Coronary Artery Disease, Based Solely on MSCT Imaging Utilizing GE Healthcare Revolution CT and HeartFlow FFRCT.
Status: WITHDRAWN
Conditions: Multivessel Coronary Artery Disease
Interventions: RADIATION: Multi-sliced computed tomography (MSCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Effect of XmAb®5871 on Disease Activity in Patients With IgG4-Related Disease (RD)
Status: COMPLETED
Conditions: IgG4-RD
Interventions: BIOLOGICAL: XmAb5871
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab, High Dose Methylprednisolone, Ofatumumab and Lenalidomide Consolidative Therapy for Untreated CLL/SLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: High Dose Methylprednisolone (HDMP)|DRUG: Ofatumumab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Imaging in Patients With Large Vessel Vasculitis to Predict Further Disease Course
Status: COMPLETED
Conditions: Giant Cell Arteritis|Large Vessel Giant Cell Arteriitis
Interventions: DIAGNOSTIC_TEST: Magnet Resonance Imaging (MRI)|DIAGNOSTIC_TEST: PET/CT analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study for Treatment-naïve IOPD Babies to Evaluate Efficacy and Safety of ERT With Avalglucosidase Alfa
Status: RECRUITING
Conditions: Glycogen Storage Disease Type II
Interventions: DRUG: avalglucosidase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Interest of Ultra-high Frequency Doppler Ultrasound (UFDU) in the Surgical Management of Patients Operated in an Awake Condition for a Cerebral Tumor
Status: COMPLETED
Conditions: Cerebral Tumor
Interventions: OTHER: High Frequence Ultrasound Doppler (HFUD) utilisation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability Study of Cycloset in Treatment of Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Cycloset|DRUG: Usual Diabetes Therapy plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients
Status: RECRUITING
Conditions: Multiple Myeloma|Hematopoietic Stem Cell Mobilization
Interventions: DRUG: Etoposide|DRUG: Cytarabine|DRUG: Pegfilgrastim|DRUG: Cyclophosphamide|DRUG: G-CSF|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients
Status: COMPLETED
Conditions: Stress Ulcer Prophylaxis
Interventions: DRUG: Esomeprazole|DRUG: Cimetidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol
Status: TERMINATED
Conditions: Sturge Weber Syndrome|Port-wine Mark
Interventions: DRUG: Timolol|DRUG: Preservative free artificial tear gel.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
Status: RECRUITING
Conditions: Preeclampsia|Gestational Hypertension|Hypertensive Disorder of Pregnancy
Interventions: DRUG: Antihypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facilitating Alcohol Screening and Treatment (FAST)
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: OTHER: Virtual Practice Facilitation with e-Learning|OTHER: Virtual Practice Facilitation without e-Learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Isonicotinic Acid Hydrazide Pretreatment With Misoprostol Induction of Abortion in First-trimester Missed Miscarriage
Status: UNKNOWN
Conditions: Abortion, Missed
Interventions: DRUG: Isonicotinic Acid|DRUG: Placebo|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Korea Comirnaty Post-marketing Surveillance
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Vaccines|Adverse Effects|SARS-CoV-2|Safety
Interventions: BIOLOGICAL: Tozinameran 12 Years of age and older|BIOLOGICAL: Tozinameran 5 to 11 Years of age|BIOLOGICAL: Tozinameran 6 months to 4 years of age|BIOLOGICAL: Riltozinameran 12 Years of age and older|BIOLOGICAL: Famtozinameran 12 Years of age and older|BIOLOGICAL: Famtozinameran 5 to 11 Years of age|BIOLOGICAL: Raxtozinameran 12 years of age and older|BIOLOGICAL: Raxtozinameran 6 months to 4 years of age
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sulindac and Epirubicin in Treating Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: epirubicin hydrochloride|DRUG: sulindac|OTHER: immunologic technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Baduanjin Qigong Exercise on Ankylosing Spondylitis: A Randomized Controlled Study
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Qigong exercise program|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase Ib Study of Olaparib Plus Weekly Carboplatin and Paclitaxel in Relapsed Ovarian Cancer
Status: UNKNOWN
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Uterine Cancer
Interventions: DRUG: Olaparib|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Divalproex Sodium in the Treatment of PTSD (Post-Traumatic Stress Disorder)
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: Divalproex|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Post Mastectomy With Intraoperative Ketamine
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative|Post-Mastectomy Chronic Pain Syndrome
Interventions: DRUG: Ketamine|OTHER: Placebo saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Validation of a Fractional Administration Device for Holmium-166 SIRT
Status: COMPLETED
Conditions: Liver Cancer|Liver Metastasis Colon Cancer|Primary Liver Cancer
Interventions: DEVICE: Fractional administration device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antiviral Activity of AZD7295 in HCV Carriers
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: AZD7295|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sternum Guard in Post Cardiac Surgery Patient
Status: COMPLETED
Conditions: Coronary Artery Disease|Valvular Heart Disease|Congenital Heart Disease in Adolescence|Post Operative Wound Infection|Surgical Site Infection|Postoperative Hemorrhage
Interventions: OTHER: Sternum Guard|OTHER: Bone Wax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Depth of Anesthesia on Pupillary Reactivity to a Standardized Stimulus
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Remifentanil|DRUG: propofol|DEVICE: TCI|PROCEDURE: Tetanic stimulation|DEVICE: Algiscan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The GORE® VIAFORT Vascular Stent IVC Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Thromboses|Venous Disease|Venous Leg Ulcer|Venous Stasis|Venous Ulcer|Venous Stenosis|Venous Occlusion|Vein Thrombosis|Vein Occlusion|Vein Disease
Interventions: DEVICE: GORE® VIAFORT Vascular Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evidence-based Family Support Program for Parents and Children in Palestine: A Theory-based Intervention
Status: RECRUITING
Conditions: Adolescent|Psychopathology|Parent-Child Relations|Violence
Interventions: BEHAVIORAL: Promoting Positive Family Futures|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Morphology and Functional Magnetic Resonance Imaging (MRI) Muscle Patients With Muscular Dystrophy Type FSHD Benefiting a Physical Training Introduced.
Status: COMPLETED
Conditions: Muscular Dystrophy|Facioscapulohumeral
Interventions: DEVICE: MRI|PROCEDURE: Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erector Spinae Plane Block Versus Paravertebral Block During Non-intubated Thoracoscopic Lung Resections.
Status: TERMINATED
Conditions: Lung Neoplasms
Interventions: PROCEDURE: Paravertebral Block (PVB)|PROCEDURE: Erector Spinae Plane Block (ESPB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Behandling af Boern Med Foedevareallergi Med Omalizumab (Xolair)
Status: COMPLETED
Conditions: Food Allergy
Interventions: DRUG: Omalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Levalbuterol for Treatment of Status Asthmaticus in Children
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Racemic albuterol (R+S albuterol)|DRUG: Levalbuterol (R albuterol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Digestive Damage and Associated Predictive Factors in Crohn's Disease 5 to 10 Years After Diagnosis
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: PROCEDURE: Abdominal MRI|PROCEDURE: Upper endoscopy|PROCEDURE: Colonoscopy|PROCEDURE: Pelvic MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Neurocognition After Cerebrovascular Intervention
Status: RECRUITING
Conditions: Carotid Artery Diseases|Neurocognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: Neurocognitive Assessments|DIAGNOSTIC_TEST: Measurements of inflammatory biomarkers|PROCEDURE: Carotid Artery Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: It's WeWomen Plus Intervention for Health, Safety and Empowerment
Status: COMPLETED
Conditions: Violence, Domestic|Violence-Related Symptom|Violence, Physical|Violence, Sexual|Violence, Gender-Based|Violence
Interventions: BEHAVIORAL: WeWomen Plus technology based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of RTX Locator Attachments for Implant-supported Mandibular Complete Overdenture
Status: COMPLETED
Conditions: Vertical Alveolar Bone Loss
Interventions: PROCEDURE: surgical placement of long dental implants|DEVICE: overdenture supported by RTX attachment system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversible Pulmonary Artery Banding as Simplified Management of End-stage Dilated Left Ventriculopathy in Early Life
Status: TERMINATED
Conditions: Acute on Chronic Systolic Congestive Heart Failure
Interventions: PROCEDURE: Reversible Pulmonary Artery Banding|PROCEDURE: GORE-TEX DualMesh EMERGE PLUS Biomaterial
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon|Adenocarcinoma of the Rectum|Stage I Colon Cancer|Stage I Rectal Cancer|Stage II Colon Cancer|Stage II Rectal Cancer|Stage III Colon Cancer|Stage III Rectal Cancer
Interventions: DRUG: resveratrol|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Single and Multiple Doses HRS9531 Tablets in Healthy Subjects
Status: RECRUITING
Conditions: Overweight or Obesity; Type 2 Diabetes
Interventions: DRUG: HRS9531|DRUG: Placebo|DRUG: HRS9531|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Pharmacological Neuromodulation on Leg Motor Activity in Patients With SCI Treated With EES
Status: COMPLETED
Conditions: Spinal Cord Injuries|Drug Effect
Interventions: DRUG: Buspirone|DRUG: Levodopa-Carbidopa|DRUG: Buspirone + Levodopa-Carbidopa|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness and Safety of Desloratadine (Aerius) Syrup in Children With Allergic Skin Inflammation (P03475)
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Propofol Sedation for Magnetic Resonance Imaging in Pediatric Patients
Status: COMPLETED
Conditions: Multiparametric Magnetic Resonance Imaging|Propofol Adverse Reaction|Sedation Complication|Anesthesia; Adverse Effect
Interventions: DRUG: Propofol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Elbow Fracture|Elbow Injury|Elbow Dislocation
Interventions: DRUG: Lactose Placebo|DRUG: Ketotifen Fumarate 2mg|DRUG: Ketotifen Fumarate 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailored Intervention to Improve Patient Adherence to Secondary Stroke Prevention Medication
Status: COMPLETED
Conditions: Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: Complex tailored intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Stimulant Use Disorder|Substance-related Disorders
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Clinical Outcomes of the Vanguard XP Bicruciate Knee System
Status: TERMINATED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis|Lower Limb Deformity|Post-traumatic Deformity|Complications, Arthroplasty
Interventions: DEVICE: Vanguard XP Bicruciate Knee System|DEVICE: Vanguard CR Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin-induced Portal Hypertension
Status: UNKNOWN
Conditions: Gastroesophageal Varices Hemorrhage|Colorectal Cancer|Received Oxaliplatin-based Chemotherapy
Interventions: PROCEDURE: Individualized Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Albumin-bound Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Patients Receiving Neoadjuvant Chemotherapy for Advanced Ovarian, Fallopian Tube or Peritoneal Cancer: A Phase 2 Single Center Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: albumin-bound paclitaxel|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shear-Wave Elastography
Status: ENROLLING_BY_INVITATION
Conditions: Ventral Incisional Hernia
Interventions: PROCEDURE: Elective Midline Laparotomy|PROCEDURE: Imaging: Ultrasound|OTHER: Tensiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
Status: TERMINATED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Metformin group|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Mesh Used in Two-staged Breast Reconstruction
Status: RECRUITING
Conditions: Breast Cancer|Radiation|Breast Reconstruction|Synthetic Mesh
Interventions: PROCEDURE: TiLoop Bra mesh in expander-implant breast reconstrution|PROCEDURE: sub-pectoral expander-implant breast reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-interventional Study With Ectoin Containing and/or Decongesting Nasal Spray in Patients With Rhinosinusitis
Status: COMPLETED
Conditions: Acute Rhinosinusitis
Interventions: DRUG: Xylometazoline Nasal Spray|DEVICE: Ectoin Rhinosinusitis Nasal Spray
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal Clinical Evaluation of the HPV Assay on the BD VIPER LT System With Cervical Specimens
Status: COMPLETED
Conditions: Cervical Neoplasms|Human Papillomavirus
Interventions: DEVICE: BD HPV Assay on Viper LT|PROCEDURE: Colposcopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reliability of Newly-acquired Gait in Toddlers With a Typical Development and a Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Gait, Spastic|Reliability
Interventions: OTHER: gait analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fed Bioequivalence Study of Divalproex Sodium Delayed-Release Tablets, 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DEPAKOTE® Tablets, 500 MG|DRUG: DIVALPROEX SODIUM DELAYED-RELEASE TABLETS, USP, 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Trial to Examine the Effect of Natural Anti- Obesity Agent (Phaseolus Vulgaris) Among Women of Lahore
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DIETARY_SUPPLEMENT: Phaseolus Vulgaris|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dynamic Monitoring of ctDNA and HPV DNA in Plasma for the Early Prediction of Recurrence After Cervical Cancer Surgery
Status: RECRUITING
Conditions: cfHPV DNA in Plasma of Cervical Cancer Patients
Interventions: DIAGNOSTIC_TEST: Assess the risk of recurrence and the efficacy of medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Effectiveness of Sambiloto Herbs (Andrographis Paniculata) and Brisk Walking Exercise on Blood Pressure of Obese Patients
Status: NOT_YET_RECRUITING
Conditions: MeSH
Interventions: DIETARY_SUPPLEMENT: Andrographis paniculata|BEHAVIORAL: Brisk Walking Exercise|OTHER: Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT