pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tangningtongluo Tablet in the Treatment of Non-proliferative Diabetic Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Type2 Diabetes|Diabetic Retinopathy
Interventions: DRUG: Tangningtongluo tablets|DRUG: Calcium dobesilate capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CAR-pNK Cell Immunotherapy for Relapsed/Refractory CD33+ AML
Status: UNKNOWN
Conditions: Acute Myelogenous Leukemia|Acute Myeloid Leukemia|Acute Myeloid Leukemia With Maturation|Acute Myeloid Leukemia Without Maturation|ANLL
Interventions: BIOLOGICAL: anti-CD33 CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Verafilcon A|DEVICE: Etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Testing Benefits of Ursolic Acid (UA) as a Countermeasure To Myopenia and Insulin Resistance in Chronic Spinal Cord Injury (SCI)
Status: RECRUITING
Conditions: Spinal Cord Injuries|Tetraplegia|Paraplegia|Muscle Loss|Atrophy, Muscular|Insulin Resistance
Interventions: DRUG: Ursolic Acid|OTHER: Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC)
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis|Cholangiocarcinoma
Interventions: DIAGNOSTIC_TEST: MR/MRCP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Blood-stage Controlled Human Plasmodium Falciparum Malaria Infection in Tanzania
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum
Interventions: BIOLOGICAL: P. falciparum infected erythrocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Virtual Reality Compared to Other Forms of Optokinetic Stimulation in the Rehabilitation of Vestibular Syndromes.
Status: COMPLETED
Conditions: Vestibular Syndrome|Optokinetic Stimulation
Interventions: OTHER: Vestibular rehabilitation with virtual reality|OTHER: Standard optokinetic stimulator or dynamic visual surround
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Long-Chain Polyunsaturated Fatty Acid Supplementation on Toddler Cognition
Status: COMPLETED
Conditions: Infant Development
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid (DHA) and arachidonic acid (ARA)|DIETARY_SUPPLEMENT: Corn oil placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bare-metal Stent vs Covered Stent in Chinese Patients With Subclavian Occlusive Lesions
Status: UNKNOWN
Conditions: Subclavian Occlusion
Interventions: PROCEDURE: Stent implantation of subclavian artery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Safety & Efficacy of Autologous Human Platelet Lysate in Lateral Epicondylitis (Tennis Elbow)
Status: UNKNOWN
Conditions: Lateral Epicondylitis (Tennis Elbow)
Interventions: BIOLOGICAL: Autologous Human Platelet Lysate|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRehabilitiation in Elective Frail and Elderly Cardiac Surgery PaTients
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Valvular Heart Disease
Interventions: BEHAVIORAL: PREHAB Workshop|BEHAVIORAL: PREHAB Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aneurysm Packing With the Expandable TrelliX Coil System - A Prospective Safety Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Ruptured or Unruptured Cerebral Aneurysms
Interventions: DEVICE: TrelliX Embolic Coil System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Speckle Contrast Imaging, Surgical Eye & ICG Fluorescence Imaging for Perfusion Assessment of the Gastric Conduit
Status: RECRUITING
Conditions: Oesophageal Cancer
Interventions: DEVICE: Laser Speckle Contrast Imaging using the PerfusiX-Imaging device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Single-Dose Efficacy of an Albuterol Breath-Actuated Inhaler (Albuterol-HFA-BAI) Versus an Albuterol Metered-Dose Inhaler (Albuterol-HFA-MDI) in Participants With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol-HFA-MDI|DRUG: Albuterol-HFA-BAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of PM00104 (Zalypsis®) in Patients With Advanced and/or Metastatic Endometrial or Cervical Cancer Previously Treated With One Line of Systemic Chemotherapy
Status: TERMINATED
Conditions: Uterine Cervical Cancer|Endometrial Cancer
Interventions: DRUG: Zalypsis ( PM00104)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis
Status: UNKNOWN
Conditions: Bladder Pain Syndrome
Interventions: DRUG: intravesical onabotulinumtoxinA injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soy and Lipoproteins in Postmenopausal Women
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Diseases|Heart Diseases|Menopause
Interventions: DIETARY_SUPPLEMENT: Soy|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intranasal Oxytocin for Infants With Prader-Willi Syndrome
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effect of Adjunctive Vivomixx® in Patients With Cirrhosis and Spontaneous Bacterial Peritonitis (SBP)
Status: WITHDRAWN
Conditions: Spontaneous Bacterial Peritonitis
Interventions: DRUG: Vivomixx®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotic Lactobacillus GG to Eliminate VRE Colonization
Status: TERMINATED
Conditions: Vancomycin Resistant Enterococcal Colonization
Interventions: BIOLOGICAL: Lactobacillus GG or Culturelle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for the Assessment of the Benefits of a Novel Mesh Nebulizer in the Treatment of Patients With Stable COPD
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: InnoSpire Go|DEVICE: Jet Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms of Clinically Designed Improvisatory Music for Alzheimer's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Clinically Designed Improvisatory Music
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Aripiprazole (Abilify) in Children With ADHD (Attention Deficit Hyperactivity Disorder)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses
Status: RECRUITING
Conditions: Upper Limb Amputees
Interventions: DEVICE: Chronically Implanted Neural and Muscular Interface
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: SUSPENDED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate|DRUG: Efavirenz|DRUG: Emtricitabine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: ZD1839 (IRESSA™) in Combination With Docetaxel & Cisplatin in Subjects With Metastatic Head & Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: ZD1839 (IRESSA™)|DRUG: Docetaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Anterior Cruciate Ligament Versus Conventional Reconstruction
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injuries
Interventions: PROCEDURE: Individualised ACL reconstruction|PROCEDURE: Conventional ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sunfiber and the Microbiota
Status: COMPLETED
Conditions: Diet Modification
Interventions: DIETARY_SUPPLEMENT: Low fiber|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: High fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Performance of Biologic Mesh Materials in Abdominal Wall Reconstruction
Status: RECRUITING
Conditions: Ventral Hernia
Interventions: DEVICE: Strattice biologic mesh|DEVICE: Permacol biologic mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nasal Steroids After FESS in CRSwNP
Status: COMPLETED
Conditions: Sinusitis|Nasal Polyps
Interventions: DRUG: fluticasone nasal spray|DRUG: Budesonide head upright|DRUG: Budesonide head forward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Gadolinium Texaphyrin in Treating Patients With Supratentorial Glioblastoma Multiforme
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma
Interventions: PROCEDURE: conventional surgery|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: stereotactic radiosurgery|DRUG: motexafin gadolinium|PROCEDURE: magnetic resonance imaging|PROCEDURE: spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paricalcitol Addition to Chemotherapy in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Paclitaxel protein bound|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Decision-Making for Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Web-based decision aid plus personalized risk assessment|BEHAVIORAL: Web-based decision aid alone|BEHAVIORAL: Generic website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Mouthpiece With Integrated Cheek Support vs. Manual Cheek Support During Respiratory Oscillometry
Status: RECRUITING
Conditions: Respiratory Morbidity|Lung Function Decreased
Interventions: DEVICE: Mouthpiece with cheek-holder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis
Status: RECRUITING
Conditions: Obesity|Ulcerative Colitis
Interventions: DEVICE: Apollo Endoscopic Suture System|BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine Efficacy and Safety in Preventing SARS-CoV-2 Infection and COVID-19 Disease Severity During Pregnancy and Postpartum
Status: COMPLETED
Conditions: Pregnancy Related|COVID|Covid-19
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Botulinum Toxin Injection in the Tennis Elbow Treatment
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: DRUG: Botulinum Toxin A Injection|DRUG: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote and Intensive Program for Physical Activity Promotion for People With Type 2 Diabetes (The PRACTICE Trial)
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Control group|OTHER: Physical activity promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tDCS on Precuneus in MCS: Repeated Stimulations
Status: COMPLETED
Conditions: Patients in Minimally Conscious State After a Severe Brain Injury
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: LY3556050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Chrysanthemum Flower Oil and Its Dose-dependency on Hyperuricemia
Status: COMPLETED
Conditions: Hyperuricemia
Interventions: DIETARY_SUPPLEMENT: 200 mg of chrysanthemum flower oil|DIETARY_SUPPLEMENT: 300 mg of chrysanthemum flower oil|DIETARY_SUPPLEMENT: 400 mg of chrysanthemum flower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Can Urinary Concentrations of TIMP2 and IGFBP7 be Used to Predict Early Acute Renal Failure Following Cardiac Arrest?
Status: COMPLETED
Conditions: Renal Failure|Heart Failure
Interventions: OTHER: Analysis of urinary levels of TIMP2 and IGFBP7 within 6 hours after cardiac circulatory arrest
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Near-infrared Imaging Coupled With Indocyanine Green for Intraoperative Control of Resection Margins in ENT Surgery
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Can a Specific OMT Protocol Influence Patient Pain and Associated Analgesia Use for Primary Headache Disorders?
Status: NOT_YET_RECRUITING
Conditions: Headache Disorders|Headache|Analgesia|Opioid Use|Osteopathy
Interventions: OTHER: Osteopathic Manipulative Treatment (OMT)|OTHER: Sham Light touch arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer
Status: RECRUITING
Conditions: Urothelial Carcinoma|Urothelial Cancer|Lung Neoplasms|Small Cell Lung Cancer|Prostate Cancer
Interventions: DRUG: EP0057|DRUG: olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of a Device to Evaluate the Neuromuscular Function in Assessing Muscle in Facial Paralysis Patients
Status: COMPLETED
Conditions: Facial Nerve Palsy
Interventions: DEVICE: MyotonPRO|DEVICE: non-invasive electromyography (EMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Severe Aplastic Anemia
Status: UNKNOWN
Conditions: Aplastic Anemia
Interventions: OTHER: Human umbilical cord-derived MSCs and cyclosporin A|OTHER: cyclosporin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label, Multicenter, Randomized Phase II Trial of Treatment With Cisplatin and Pemetrexed or Cisplatin and Oral Vinorelbine in Chemotherapy Naïve Patients Affected by Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer With High Thymidylate Synthase Expression
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung|Secondary|Advanced Stage IIIB|High Thymidylate Synthase Expression
Interventions: DRUG: Oral vinorelbine|DRUG: Cisplatin|DRUG: Maintenance with Metronomic Oral Vinorelbine|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Maintenance with Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome
Status: NOT_YET_RECRUITING
Conditions: Essential Hypertension|Metabolic Syndrome
Interventions: DRUG: Telmisartan|DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Umbilical Cord Mesenchymal Stem Cell in Patients With Cirrhosis Due to Hepatitis B (Compensation Stage)
Status: UNKNOWN
Conditions: Cirrhosis Due to Hepatitis B
Interventions: BIOLOGICAL: UC-MSCs|BIOLOGICAL: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control (IMPACTS)
Status: COMPLETED
Conditions: Hypertension|Blood Pressure
Interventions: BEHAVIORAL: Multicomponent Intervention|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peribulbar Block: Lidocaine-bupivacaine vs Lidocaine-bupivacaine-fentanyl
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: peribulbar block 1 lidocaine/bupivacaine|DRUG: peribulbar block 2 lidocaine/bupivacaine/fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Intervention "Food, Fun and Family" on Sleep Bruxism in Children
Status: UNKNOWN
Conditions: Sleep Bruxism, Childhood
Interventions: BEHAVIORAL: Food, fun and family|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Warming Techniques in Patients Undergoing Open Abdominal Surgery in Litotomy Position
Status: COMPLETED
Conditions: Temperature Change, Body
Interventions: DEVICE: HICO-VARIOTHERM 550|DEVICE: Mistral-Air Plus forced air warming device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Eradication of Gut Microbiota
Status: COMPLETED
Conditions: Diabetes|Obesity|Osteoporosis|Inflammation
Interventions: DRUG: meropenem, gentamicin, vancomycin (together)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pazopanib in Treating Patients With Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Advanced Malignant Mesothelioma|Localized Malignant Mesothelioma|Recurrent Malignant Mesothelioma
Interventions: OTHER: laboratory biomarker analysis|DRUG: pazopanib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Empagliflozin Works in Japanese People With Type 2 Diabetes Who Are Older Than 65 Years
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective and Comparative Analysis of Arthroscopic and Open Surgery for Hallux Rigidus
Status: WITHDRAWN
Conditions: Hallux Rigidus
Interventions: PROCEDURE: Arthroscopic or open surgery for hallux rigidus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablative tReatment of Inoperable REnal Cell Carcinoma Using STereotactic Body Radiotherapy (ARREST-study)
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: ARREST-study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Happy Nurse Project: Lifestyle Interventions to Maintain Healthy Mental State in Hospital Nurses
Status: COMPLETED
Conditions: Depressive Disorder|Anxiety Disorders
Interventions: BEHAVIORAL: Mindfulness-based stress management program|DIETARY_SUPPLEMENT: Omega-3 fatty acids pills|BEHAVIORAL: Psychoeducation leaflet|DIETARY_SUPPLEMENT: Placebo pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Web-based Care Management for Poorly Controlled Type 2 Diabetes Mellitus: a Randomized, Controlled Trial
Status: WITHDRAWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: Diabetes software and device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIAGALS: Relation Between Tar DNA Binding Protein(TDP)-43 et Nrf-2 in ALS: a Track to Improve Diagnosis and Prognosis of the Disease
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Blood sample|BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Keratoconjunctivitis|Conjunctivitis
Interventions: DRUG: FK506|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rheumatoid Arthritis (RA) Moderate to Low Disease Activity Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Certolizumab pegol|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endo-epicardial vs Endocardial-only Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy (EPIC-VT)
Status: RECRUITING
Conditions: Ischemic Cardiomyopathy|Catheter Ablation of Ventricular Tachycardia
Interventions: PROCEDURE: Endo-epicardial ablation|PROCEDURE: endocardial ablation only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Intravitreal Microplasmin in Infants and Children Scheduled for Vitrectomy
Status: COMPLETED
Conditions: Vitrectomy
Interventions: DRUG: Ocriplasmin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Activity & Safety Study of Lenalidomide & Rituximab as Non-chemotherapy Based Therapy on Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomida and Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Frequency Deep Sclerotomy (HFDS) ab Interno a Combination Surgical Intervention Using Cataract Surgery to Lower IOP
Status: UNKNOWN
Conditions: Cataract|Glaucoma|POAG
Interventions: PROCEDURE: Combined sclerotomy ab interno and phaco|PROCEDURE: Phacoemulsification with IOL implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in the Treatment of Chronic Hepatitis C Virus in Participants Who Are Co-Infected With Human Immunodeficiency Virus:C-EDGE CO-INFXN (MK-5172-061)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Grazoprevir 100 mg/Elbasvir 50 mg fixed-dose combination tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Oranges on Cardiovascular Health
Status: COMPLETED
Conditions: Blood Pressure|Endothelial Dysfunction|Cardiovascular Disease Risk Reduction
Interventions: DIETARY_SUPPLEMENT: Citrus supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering
Status: COMPLETED
Conditions: Shivering|Nausea and Vomiting, Postoperative
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of 18FDG-PET-CT for Pacing or Defibrillation Lead Infection
Status: COMPLETED
Conditions: Infections of the Implanted Material|Endocarditis
Interventions: DEVICE: Whole-body 18FDG-PET-CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: KM-001 Cream for Treatment of Pruritus in Adult Patients With Lichen Simplex Chronicus (LSC)
Status: COMPLETED
Conditions: Lichen Simplex Chronicus
Interventions: DRUG: IMP Application KM-001|DIAGNOSTIC_TEST: Chemistry|DIAGNOSTIC_TEST: Hematology|DIAGNOSTIC_TEST: Urinalysis|DIAGNOSTIC_TEST: Serelogy|DIAGNOSTIC_TEST: 12-Lead ECG|DIAGNOSTIC_TEST: Pregnancy test|DIAGNOSTIC_TEST: Blood PK sampling|PROCEDURE: Physical Examination|PROCEDURE: Vital signa|DIAGNOSTIC_TEST: Investigator's Global Assessment|DIAGNOSTIC_TEST: Itch Assessment via PP-NRSj|OTHER: E-diary data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery
Status: RECRUITING
Conditions: Glioma
Interventions: DIAGNOSTIC_TEST: Immunohistochemistry or genetic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Compare the Effects of Two Propellants in Adults With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo 152a|DRUG: Placebo 134a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining the Role of the Orexin System in Sleep and Stress in Persons With Opioid Use Disorder
Status: RECRUITING
Conditions: Sleep Disturbance|Opioid-use Disorder
Interventions: DRUG: Suvorexant|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Protocol Thymus Transplantation
Status: COMPLETED
Conditions: Poor Thymic Function|Immunodeficiency|Athymia|Immunoreconstitution|Thymus Transplantation|Low T Cell Numbers
Interventions: BIOLOGICAL: Cultured Thymus Tissue|PROCEDURE: Blood Draw|DRUG: Rabbit Anti-Thymocyte Globulin and Cyclosporine or Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wearable MCI to Reduce Muscle Co-activation in Acute and Chronic Stroke
Status: RECRUITING
Conditions: Stroke|Stroke, Acute
Interventions: BEHAVIORAL: MCI|BEHAVIORAL: Sham MCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CD155 Expression in Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DIAGNOSTIC_TEST: Flow cytometric immunophenotyping|DIAGNOSTIC_TEST: Complete blood count|DIAGNOSTIC_TEST: Bone marrow aspiration|DIAGNOSTIC_TEST: Cytogenetic testing|DIAGNOSTIC_TEST: FLT3-ITD using High resolution melting curve (HRM) analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Cebranopadol
Status: COMPLETED
Conditions: Pharmacokinetic
Interventions: DRUG: Cebranopadol 200 μg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Active product|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl as Additives to Bupivacaine in Pott's Fracture
Status: NOT_YET_RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Fentanyl|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nasal Human Abuse Potential of PTI-821
Status: COMPLETED
Conditions: Opioid Abuse Nondependent
Interventions: DRUG: PTI-821 capsule Manipulated|DRUG: PTI-821 Non-manipulated|DRUG: OxyContin|OTHER: Placebo|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Digitally Assisted Behavioral Physical Activity Intervention in Fibromyalgia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia|Physical Inactivity
Interventions: BEHAVIORAL: Digitally assisted behavioral physical activity intervention|BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing Lecozotan SR Two 5-mg Tablets Vs. Lecozotan SR One 10-mg Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: lecozotan SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Ciclesonide Inhaled Once Daily Versus Fluticasone Propionate Inhaled Twice Daily in Children With Asthma (6 to 11 y) (BY9010/M1-206)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Ciclesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Corneal Endothelial Cell Density Changes, When Mapracorat Ophthalmic Suspension 3%, is Administered for 14 Days
Status: COMPLETED
Conditions: Corneal Endothelial Cell Changes
Interventions: DRUG: Mapracorat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Pharmacokinetic and Safety Study of Moxidectin to Identify an Optimal Dose for Treatment of Children 4 to 11 Years
Status: COMPLETED
Conditions: Onchocerciasis
Interventions: DRUG: Moxidectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine patch|DEVICE: e-cigarette|DRUG: Nicotine|BEHAVIORAL: Behavioural support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Totally Intravenous and Inhalation Anesthesia for Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Total intravenous anesthesia|DRUG: Inhalation Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Superior Rectal Arterial Embolization in Hemorrhoidal Disease
Status: RECRUITING
Conditions: Hemorrhoids
Interventions: PROCEDURE: Rubber band ligatures (RBL)|PROCEDURE: Superior Rectal Artery Embolization (SRAE)|PROCEDURE: Doppler-Guided Hemorrhoidal Artery Ligation (DG-HAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bae: A Smartphone Application for a Better Following Adolescents at Risk of Suicidal Behavior: Study of Acceptability and Preliminary Results of Efficacy
Status: UNKNOWN
Conditions: Suicide Attempt|Suicidal Ideation
Interventions: OTHER: bae application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immediate Unselected Coronary Angiography Versus Delayed Triage in Survivors of Out-of-hospital Cardiac Arrest Without ST-segment Elevation
Status: COMPLETED
Conditions: Out-of-hospital Cardiac Arrest
Interventions: OTHER: Immediate coronary angiography|OTHER: Delayed/selective coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
Status: RECRUITING
Conditions: Diabete Type 2|Abdominal Obesity
Interventions: PROCEDURE: Sampling of adipose tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Clinical Utility of the Dexcom G6 Continuous Glucose Monitoring Device for Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DEVICE: Dexcom continuous glucose monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Acute Dietary Sodium on Cerebrovascular Reactivity and Blood Pressure Reactivity
Status: COMPLETED
Conditions: Blood Pressure|Cerebrovascular Reactivity
Interventions: OTHER: Low Sodium Meal (138 mg sodium)|OTHER: High Sodium Meal (1,495 mg sodium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Masitinib in Treatment of Patients With Severe Persistent Asthma Treated With Oral Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Masitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.
Status: RECRUITING
Conditions: Vulvovaginal Candidiasis|Vaginal Yeast Infections
Interventions: DRUG: JUVIA zinc containing vaginal gel treatment|DRUG: Fluconazole 150Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Age and Gender on the PK and Tolerability of Finafloxacin
Status: COMPLETED
Conditions: Pharmacokinetic and Tolerability of Finafloxacin
Interventions: DRUG: 400 mg finafloxacin (2 x 200 mg tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Balanced Crystalloid Versus 5% Albumin on Endothelial Glycocalyx Degradation in Patients Undergoing Off-pump Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Occlusive Disease(CAOD)
Interventions: DRUG: Plasma solution-A injection|DRUG: 5% Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: e- Ab Sensor - Based Real-time Diagnosis of Influenza Virus
Status: UNKNOWN
Conditions: Influenza Caused by Unspecified Influenza Virus
Interventions: DEVICE: Electrosensing antibody probing system (e- Ab sensor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Chinese Mild to Moderate Hypertensive Patients Comparing the Efficacy of Co-Diovan With Diovan.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan plus hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Radiation Therapy|DRUG: Temozolomide Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy
Status: TERMINATED
Conditions: Primary Mitochondrial Myopathy
Interventions: DRUG: Bocidelpar|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temporomandibular Joint Arthrocentesis With Infiltration of PRP + Ropivacaine Versus PRP
Status: ENROLLING_BY_INVITATION
Conditions: Temporomandibular Joint Disorders
Interventions: DRUG: Ropivacaine injection|PROCEDURE: temporomandibular joint arthrocentesis|DRUG: PRP injection|DRUG: Ringer's Lactate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Fixation Method in Total Knee Arthroplasty - Low Viscosity Versus High Viscosity Bone Cement
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DEVICE: Osteopal G vs. Refobacin-Palacos R bone cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies
Status: RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified|High-grade B-cell Lymphoma|Primary Mediastinal Large B-cell Lymphoma (PMBCL)|Transformed Follicular Lymphoma (tFL)|Follicular Lymphoma Grade 3B
Interventions: BIOLOGICAL: P-CD19CD20-ALLO1|DRUG: Rimiducid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Osteosynthesis, Primary Hemi-arthroplasty, and Non-surgical Management for Fractures of the Proximal Humerus
Status: UNKNOWN
Conditions: Proximal Humeral Fractures
Interventions: PROCEDURE: Non-surgical management|PROCEDURE: Osteosynthesis|PROCEDURE: Hemiarthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Investigate the Effects of Increased Dialysate Magnesium and Dialysate Bicarbonate on the Calcification Propensity of Serum
Status: COMPLETED
Conditions: End Stage Renal Failure on Dialysis|Vascular Calcification
Interventions: DEVICE: Magnesium|DEVICE: Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of a Single or Multiple Ascending Doses of CPX101
Status: NOT_YET_RECRUITING
Conditions: Overweight and Obesity
Interventions: BIOLOGICAL: CPX101 or placebo 80mg single dose|BIOLOGICAL: CPX101 or placebo 120mg single dose|BIOLOGICAL: CPX101 or placebo 160mg single dose|BIOLOGICAL: CPX101 or placebo 80mg Q2W|BIOLOGICAL: CPX101 or placebo 120mg Q2W|BIOLOGICAL: CPX101 or placebo 160mg Q2W|BIOLOGICAL: CPX101 or placebo 200mg Q2W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease|Dry Eye Syndrome
Interventions: DRUG: AGN-242428|DRUG: AGN-231868|OTHER: AGN-242428 Vehicle|OTHER: AGN-231868 Vehicle|DRUG: Lifitegrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor
Status: TERMINATED
Conditions: Premature Birth|Premature Labor
Interventions: DRUG: Magnesium sulfate|DRUG: Oral Nifedipine or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Relative Bioavailability of Two Different Formulations of GSK3640254
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254 bis-hydrochloride salt capsule|DRUG: GSK3640254 Mesylate Salt Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurosteroids for PTSD in Veterans
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: Pregnenolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Playful Sensorimotor Training in Pediatric Brain Tumor Patients
Status: SUSPENDED
Conditions: Pediatric Cancer|Pediatric Brain Tumor|Chemotherapy-induced Peripheral Neuropathy|Sensorimotor Polyneuropathy
Interventions: BEHAVIORAL: Sensorimotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet
Status: RECRUITING
Conditions: Minor Traumatic Brain Injury|Treatment by Antiplatelet
Interventions: BIOLOGICAL: S100B protein dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC