pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Immediate Implant Placement With Provisionalization Using Different Bone Grafts as a Space Filling Material in the Maxillary Esthetic Zone
Status: UNKNOWN
Conditions: Dental Implant Failed
Interventions: PROCEDURE: Autogenous bone graft as space filling in immidiate implant placment|PROCEDURE: Deprotinized bovien as space filling in immidate implant placement|PROCEDURE: Nano-hydroxiapatite alloplast in immidiate implant placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma, IDH-Wildtype
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Surgical Procedure|BIOLOGICAL: Tiragolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
Status: TERMINATED
Conditions: Opioid Use|Post-thoracotomy Pain Syndrome|Local Anaesthetic Agent Overdose|Local Anesthetic Complication|Pain, Postoperative
Interventions: PROCEDURE: Serratus anterior block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Optimizing Pain and Rehabilitation After Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: OTHER: continuous FNB|OTHER: single femoral nerve block|OTHER: local infiltration analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Gemcitabine, Albumin-paclitaxel , Sintilimab and Bevacizumab in Unresectable Gallbladder Cancer
Status: RECRUITING
Conditions: Gallbladder Cancer|Initially Unresectable|the First Line Treatment
Interventions: DRUG: Combination of Gemcitabine, Nab-paclitaxel, Sintilimab and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3BNC117-LS and 10-1074-LS in Viremic HIV-infected Individuals
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: 3BNC117-LS|DRUG: 10-1074-LS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Soft Tissue Sarcoma
Interventions: DRUG: Lurbinectedin|RADIATION: Radiotherapy|PROCEDURE: Non-investigational surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL)
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Chlorambucil|DRUG: R-etodolac + chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pentoxifylline in the Treatment of NEC in Premature Neonates
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitating Risk-Appropriate Colorectal Cancer Testing - Testing the Cancer Risk Intake System (CRIS)
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colonic Neoplasms
Interventions: BEHAVIORAL: Tailored Printout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Two-Part Study to Evaluate the Safety and Efficacy of Image Guided Surgery Using Indocyanine Green for Intramolecular Imaging of Nervous System Tumors Compared to Standard of Care, (TumorGlow)
Status: COMPLETED
Conditions: Brain Tumor, Primary|Brain Tumor, Recurrent
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Pulmonary Health and Quality of Life in Breast Cancer Survivors: A Randomized Controlled Trial Combining Incentive Spirometry and Aerobic Exercise
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: QoL|DEVICE: lung function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
Status: RECRUITING
Conditions: Diabetes Mellitus|Type 1 Diabetes|Diabetes type1|Autoimmune Diabetes
Interventions: BIOLOGICAL: Bacillus Calmette-Guérin|BIOLOGICAL: Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulised 3% Hypertonic Saline Versus 0.9% Saline for Treating Patients Hospitalized With Acute Bronchiolitis
Status: RECRUITING
Conditions: Bronchiolitis
Interventions: DRUG: Hypertonic saline|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes
Status: COMPLETED
Conditions: Performance Enhancing Product Use|Change, Body Weight|Change, Body Temperature|Antioxidative Stress|Lactate Blood Increase|Thermal Sensation Disorders
Interventions: OTHER: PLACEBO|DIETARY_SUPPLEMENT: GLYCEROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: GnRH Antagonist Versus GnRH Agonist in Polycystic Ovary Syndrome During in Vitro Fertilization - Embryo Transfer
Status: COMPLETED
Conditions: Infertility|Polycystic Ovary Syndrome
Interventions: DRUG: GnRH antagonist (Cetrorelix)|DRUG: Conventional GnRH agonist (Triptorelin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactoferrin Versus Total Dose Infusion (TDI) For Treating Iron Deficiency Anemia in Pregnancy: Role of Nursing
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: COMBINATION_PRODUCT: Oral lactoferrin|COMBINATION_PRODUCT: TDI of LMW iron dextran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tablet Computer-based Cognitive Training in Patients With Idiopathic REM Sleep Behavior Disorder
Status: SUSPENDED
Conditions: REM Sleep Behavior Disorder
Interventions: OTHER: Tablet computer-based cognitive training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Regional Manual Therapy and Standard Physical Therapy Intervention in Females With Sacroiliac Joint Pain
Status: COMPLETED
Conditions: Sacroiliac; Sprain (Strain)
Interventions: OTHER: Regional treatment|OTHER: Standard physiotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients
Status: UNKNOWN
Conditions: Rectum Neoplasms
Interventions: PROCEDURE: L-PANP-TME|PROCEDURE: O-PANP-TME
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Near-Infrared Imaging With Indocyanine Green for Detection of Sentinel Lymph Nodes in People With Vulvar Cancer
Status: RECRUITING
Conditions: Vulvar Cancer
Interventions: PROCEDURE: ICG guided sentinel lymph node biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double Blind Randomized Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis
Status: UNKNOWN
Conditions: Hemorrhagic Cystitis|Stem Cell Transplantation|Decidual Stromal Cells
Interventions: BIOLOGICAL: Decidual stromal cells|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of GDC-0449 on the QT/QTc Interval in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GDC-0449|DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations
Status: COMPLETED
Conditions: Long QT Syndrome|Brugada Syndrome|Catecholaminergic Polymorphic Ventricular Tachycardia|Arrhythmogenic Right Ventricular Dysplasia|Hypertrophic Cardiomyopathy|Dilated Cardiomyopathy|Restrictive Cardiomyopathy
Interventions: OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Planning for ABA Employing Auxiliary Tools v2+ (TREAAT2+)
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: OTHER: Tech-enabled ABA treatment planning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis|Post-traumatic Arthritis|Rheumatoid Arthritis
Interventions: PROCEDURE: Total Knee Arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency Ablation
Status: COMPLETED
Conditions: Paroxysmal Supraventricular Tachycardia
Interventions: PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Performances of the cTOFR and the mTOFR During Reversal of Deep Neuromuscular Blockade With Sugammadex
Status: RECRUITING
Conditions: Neuromuscular Blockade|Anesthesia, General
Interventions: DEVICE: TOFscan monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Wireless Handheld 8-lead ECG Device Performance in Heart Patients (Rapid Rhythm)
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Murmurs
Interventions: DEVICE: Rapid Rhythm Handheld 8-lead ECG Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Pharmacogenomics Testing to Precision Prescriptions in Periodontal Patients
Status: UNKNOWN
Conditions: Oral Surgeries
Interventions: DRUG: Local anesthetics, IV sedation drugs and analgesics.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neihulizumab for Standard-Risk Acute Graft Versus Host Disease (GVHD)
Status: RECRUITING
Conditions: Graft-versus-host Disease
Interventions: BIOLOGICAL: Neihulizumab, 3 mg/kg|DRUG: Neihulizumab, 6 mg/kg|DRUG: Neihulizumab, 9 mg/kg|DRUG: Neihulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Caudal or Interlaminar Corticosteroid Epidural Injection for Sciatica
Status: WITHDRAWN
Conditions: Sciatica
Interventions: PROCEDURE: ultrasound-guided|PROCEDURE: interlaminar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Quality of Recovery Between Remimazolam and Propofol Anesthesia in Patients Undergoing Arthroscopic Meniscectomy
Status: COMPLETED
Conditions: Adult Patients 19 or Older Scheduled for Elective Arthroscopic Meniscectomy
Interventions: DRUG: Propofol TIVA|DRUG: Remimazolam TIVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Evaluating Persistence Of Antibody Response Elicited By 13vPnC In Healthy Adults Previously Vaccinated
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Blood draw|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Community Clinic Test of Youth Anxiety Treatment
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Cognitive behavioral therapy for youth anxiety|OTHER: Usual clinic care|BEHAVIORAL: Cognitive behavioral treatment for youth depression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Craniosacral Therapy to Treat Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Craniosacral Therapy Program|OTHER: One technique of craniosacral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Tasimelteon Alone and in Combination With a CYP3A4 Inhibitor, Ketoconazole, or a CYP3A4 Inducer, Rifampin.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: tasimelteon|DRUG: tasimelteon|DRUG: Rifampin|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Electromagnetic Stimulation as Coadjuvant in the Healing of Diaphyseal Femoral Fractures
Status: COMPLETED
Conditions: Fracture, Closed, Comminuted, Healing
Interventions: DEVICE: Electromagnetic stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Effectiveness of Intravenous Immunization With PfSPZ Vaccine in Healthy African Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Closure of Atrial Septal Defects With the AMPLATZER Septal Occluder - Post Approval Study
Status: COMPLETED
Conditions: Atrial Septal Defect
Interventions: DEVICE: AMPLATZER Septal Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Rehabilitation and Reeducation (CVRR) in Patients With Cardiac Pathologies and the 6-minute Stepper Test
Status: COMPLETED
Conditions: Cardiac Disease
Interventions: OTHER: 6 minutes step test (ST6)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: DAA Therapy in Pediatric Patients With Chronic Hepatitis C
Status: UNKNOWN
Conditions: Chronic Hepatitis c
Interventions: DRUG: Direct Acting Antivirals|DRUG: DAAs in Cirrhotics Genotype 2/3|DRUG: DAAs in Cirrhotics Genotye 1,4,5,6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications
Status: RECRUITING
Conditions: Prostate Cancer|PSA|Infection
Interventions: PROCEDURE: Systematic Transrectal biopsy (TR-Bx)|PROCEDURE: Targeted Transrectal biopsy (TR-Bx)|PROCEDURE: Systematic Transperineal biopsy (TP-Bx)|PROCEDURE: Targeted Transperineal biopsy (TP-Bx)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome
Status: COMPLETED
Conditions: Angina Pectoris|Acute Myocardial Infarction
Interventions: DEVICE: iFR|DEVICE: FFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Decision Aids for Patients With Nonvalvular Chronic Atrial Fibrillation (DA4AFib)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: DA4Afib Prototyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Active Prewarming Versus Standard Care to Prevent Perioperative Hyporthermia in Short Outpatient Surgery Under General Anesthesia
Status: COMPLETED
Conditions: Hypothermia Following Anesthesia|Hypothermia, Accidental
Interventions: DEVICE: Active Prewarming|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dabrafenib/Trametinib, BRAF or BRAF AND MEK Pre-op With BRAF and MEK Post-op, Phase IIB, Melanoma With Brain Mets,Biomarkers and Metabolites
Status: TERMINATED
Conditions: Melanoma and Brain Metastases
Interventions: DRUG: Dabrafenib 150 mg|DRUG: Trametinib 2.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenteral Nutrition for Patients Treated for Locally Advanced Inoperable Tumors of the Head and Neck
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Hypopharynx Stage III|Squamous Cell Carcinoma of the Hypopharynx Stage IV|Laryngeal Squamous Cell Carcinoma Stage III|Laryngeal Squamous Cell Carcinoma Stage IV|Oropharyngeal Squamous Cell Carcinoma Stage III|Oropharyngeal Squamous Cell Carcinoma Stage IV|Squamous Cell Carcinoma of the Oral Cavity Stage III|Squamous Cell Carcinoma of the Oral Cavity Stage IV|Locally Advanced Malignant Neoplasm
Interventions: DIETARY_SUPPLEMENT: Standard care of parenteral nutrition|DIETARY_SUPPLEMENT: Parenteral over night nutrition|BIOLOGICAL: Cetuximab|DRUG: Cisplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liposome Bupivacaine Interscalene Total Shoulder
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: liposome bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Cardiovascular Disease (CVD) Risk in HIV on Antiretroviral Therapy Over 12 Months
Status: COMPLETED
Conditions: HIV-1 Infection|Cardiovascular Disease
Interventions: OTHER: Control|OTHER: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-440|DRUG: TEZ|DRUG: IVA|DRUG: Matched Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics and Antiviral Activity of ABT-267 in HCV Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ABT-267|DRUG: ABT-450|DRUG: ABT-333|DRUG: Ritonavir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD
Status: RECRUITING
Conditions: SIAD - Syndrome of Inappropriate Antidiuresis|Hyponatremia
Interventions: DRUG: Placebo|DRUG: Apelin Low Dose|DRUG: Apelin High Dose|DRUG: Selected Apelin Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: PEAnut Anaphylaxis Predictors
Status: COMPLETED
Conditions: Peanut Hypersensitivity|Anaphylaxis
Interventions: OTHER: Questionnaire|OTHER: Peanut Skin prick test|OTHER: Fraction of exhaled nitric oxide|OTHER: Spirometry|OTHER: Serum Peanut and Ara h2 specific immunoglobulin E|OTHER: Collection of blood biomarker|OTHER: Peanut food challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: At What Time Therapeutic Plasma Concentrations of Paracetamol Are Achieved in Two Marketed Formulations
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Paracetamol formulation 1|DRUG: Paracetamol formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Efficacy and Safety of Rebel Reliever Brace in Patients With Symptomatic Medial Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Rebel Reliever|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Adding LLL Therapy to Postural Correction Exercises on Postnatal SIJ Pain
Status: COMPLETED
Conditions: Sacroiliac Joint Pain
Interventions: OTHER: LLL therapy , postural correction ex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
Status: UNKNOWN
Conditions: Stammering
Interventions: BEHAVIORAL: Modifying saccades by looking down to naval.|BEHAVIORAL: Modifying saccades by looking in air.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between FFR Guided Revascularization Versus Conventional Strategy in Acute STEMI Patients With MVD.
Status: COMPLETED
Conditions: Myocardial Infarction|Multivessel Coronary Artery Disease
Interventions: PROCEDURE: FFR-guided revascularisation strategy|PROCEDURE: randomised to guidelines group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Micronutrient Supplementation vs Iron and Folic Acid Among Pregnant Women in Cambodia
Status: ENROLLING_BY_INVITATION
Conditions: Pregnancy Related|Antenatal Care|Iron Folic Acid Supplementation
Interventions: DIETARY_SUPPLEMENT: IFA vs. MMS during pregnancy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase I Study of OncoLAR® (Registered Trademark) (NSC 685403) With/Without Tamoxifen in Patients With Osteosarcoma
Status: COMPLETED
Conditions: Neoplasm Metastasis|Osteosarcoma
Interventions: DRUG: OncoLAR® (Registered Trademark)|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study)
Status: RECRUITING
Conditions: Hepatocellular Cancer|Cholangiocarcinoma|Gallbladder Cancer|Pancreatic Cancer|Oesophageal Cancer|Stomach Cancer
Interventions: DIAGNOSTIC_TEST: FoundationOne®CDx and FoundationOne®Liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Deucravacitinib Rosacea
Status: RECRUITING
Conditions: Papulopustular Rosacea
Interventions: DRUG: Deucravacitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AMG 193 in Subjects With Advanced MTAP-null Solid Tumors
Status: RECRUITING
Conditions: Advanced MTAP-null Solid Tumors
Interventions: DRUG: AMG 193|DRUG: Docetaxel|DRUG: Comparator AMG 193 Test Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety Study of SyB C-1101 in Patients With Recurrent/Relapsed or Refractory Myelodysplastic Syndrome (MDS) - Extension Study
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: SyB C-1101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-Term Fasting During Chemotherapy in Patients With Gynecological Cancer- a Randomized Controlled Cross-over Trial
Status: COMPLETED
Conditions: Neoplasia|Cancer|Fasting
Interventions: BEHAVIORAL: initial fasting|BEHAVIORAL: Secondary fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure
Status: NOT_YET_RECRUITING
Conditions: Mid-membranous Vocal Fold Lesion
Interventions: BEHAVIORAL: Resonant voice therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Resistant Depression and Obstructive Sleep Apnea, Effect of Continuous Positive Airway Pressure (CPAP)
Status: UNKNOWN
Conditions: Depression|Sleep Apnea, Obstructive
Interventions: DEVICE: continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: DRUG: LY3556050|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EXtubation With SUctioning or With Positive End-Expiratory Pressure in Intensive Care Unit
Status: RECRUITING
Conditions: Extubation in Intensive Care Unit
Interventions: PROCEDURE: Extubation with PEEP|PROCEDURE: Endotracheal Aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daily Subjective and Objective Smartphone Measures of Illness Activity to Treat Bipolar Disorder- The MONARCA II Trial
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DEVICE: The MONARCA II system|DEVICE: Non-MONARCA II system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Lung Screening, Tobacco and Health Project
Status: COMPLETED
Conditions: Smoking, Tobacco|Tobacco-Related Carcinoma|Tobacco Use|Lung Cancer Screening
Interventions: BEHAVIORAL: Intensive Telephone Counseling (8 sessions) with nicotine replacement|BEHAVIORAL: Usual Care: Telephone counseling (3 sessions) with nicotine replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Immunosuppression Drug Weaning in Liver Recipients Exhibiting Biomarkers of High Likelihood of Tolerance
Status: TERMINATED
Conditions: Liver Transplantation
Interventions: OTHER: Immunosuppresion withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Atezolizumab|RADIATION: Stereotactic Ablative Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In-Office Tympanostomy Tube Placement in Children (OTTER)
Status: COMPLETED
Conditions: OME - Otitis Media With Effusion|AOM - Acute Otitis Media
Interventions: COMBINATION_PRODUCT: Iontophoresis & tube placement|DEVICE: Tube placement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer
Status: COMPLETED
Conditions: Breast Cancer|Drug/Agent Toxicity by Tissue/Organ|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: pyridoxine hydrochloride|DRUG: urea/lactic acid-based topical cream|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fesoterodine and Oxybutynin XL for Overactive Bladder Syndrome in Children
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Fesoterodine|DRUG: Oxybutynin XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Patients Risk Factors on the Longevity of Aesthetic Restorations
Status: UNKNOWN
Conditions: Dental Restorations Longevity|Dental Restoration Failure|Esthetics, Dental
Interventions: PROCEDURE: Restorations with nanoparticulated composites and self etch adhesives|PROCEDURE: Restorations with nanoparticulated composites and total-etch adhesives|PROCEDURE: Restorations with nanohybrid composites and self etch adhesives|PROCEDURE: Restorations with nanohybrid composites and total-etch adhesives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: GSK1325760A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Commercially Available Influenza Vaccine (Formulation 2007/2008) When Administered to Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Surface Antigen, Inactivated, Adjuvanted Influenza Vaccine, Formulation 2007-2008
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Second Level Reiki on Pain Severity and Quality of Life in Patients Receiving Hemodialysis Treatment
Status: NOT_YET_RECRUITING
Conditions: Hemodialysis
Interventions: OTHER: Distance Reiki|OTHER: Sham Reiki
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Pressure Wound Care Package on the Development of Operating Room Pressure Wound in Orthopedic Surgery
Status: COMPLETED
Conditions: Pressure Injury|Orthopedic Surgery
Interventions: OTHER: Assigned Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Adapated Physical Activity Program on Kynurenin Metabolism During Refeeding in Anorexia Nervosa : APANOR Study
Status: NOT_YET_RECRUITING
Conditions: Anorexia Nervosa
Interventions: OTHER: physical activity program (APA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phosphate Lowering in CKD Trial
Status: COMPLETED
Conditions: Chronic Kidney Disease|Cardiovascular Disease
Interventions: DRUG: Lanthanum carbonate|DRUG: placebo|DRUG: Ascorbic Acid|DRUG: Nitroglycerin|PROCEDURE: Flow-mediated dilation measurement|PROCEDURE: Aortic pulse-wave velocity|PROCEDURE: Endothelial cell collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Tear|Anterior Cruciate Ligament Rupture|Anterior Cruciate Ligament Injuries|Osteo Arthritis Knee
Interventions: DRUG: Zoledronic Acid Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The PK/PD Study of A Single Subcutaneous Injection of SHR-1209 in Healthy Subjects
Status: COMPLETED
Conditions: Hypercholesteremia
Interventions: DRUG: SHR-1209|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Pharmacist-Managed Anticoagulation Service in a University-based Family Medicine Clinic
Status: COMPLETED
Conditions: Anticoagulation|Home INR Monitoring
Interventions: DEVICE: Home INR Monitoring|PROCEDURE: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the One-way Interaction of Calcium Carbonate, Omeprazole, or Rifampin on ACP-196
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: ACP-196|DRUG: Calcium carbonate|DRUG: Omeprazole|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Health Economic Evaluation With a New Baha® Abutment Combined With a Minimally Invasive Surgical Technique
Status: COMPLETED
Conditions: Deafness|Hearing Loss|Hearing Loss, Conductive|Hearing Loss, Mixed Conductive-Sensorineural
Interventions: DEVICE: Minimally invasive surgery and BA400|DEVICE: Traditional surgery and BA300
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Repetitive Transcranial Magnetic Stimulation to Study the Role of Frontostriatal Circuit in Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DEVICE: Repetitive transcranial magnetic stimulation (rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Study of CT1812 in Mild to Moderate Alzheimer's Disease Using EEG
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: CT1812|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Evaluation With Ultrasound in Different Levels of PEEP
Status: COMPLETED
Conditions: Atelectasis|Hypertension|Lung Edema
Interventions: PROCEDURE: PEEP TITRATED|DEVICE: Use ultrasound|DEVICE: Impedance tomography|OTHER: Best PEEP for less collapse|OTHER: PEEP 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Arterial Cannulation With Ultrasound
Status: TERMINATED
Conditions: Perioperative/Postoperative Complications
Interventions: PROCEDURE: Ultrasound guided arterial cannulation|PROCEDURE: Palpation guided arterial cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients
Status: COMPLETED
Conditions: Glioblastoma|Glioma
Interventions: DRUG: Bevacizumab standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 3-year Multi-center Study to Describe Changes of OCT Parameters Under Treatment With Gilenya®
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis RRMS
Interventions: DRUG: Fingolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: RhACE2 APN01|DRUG: Physiological saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Pre-operative Window Trial of Black Cohosh in Women With Ductal Carcinoma in Situ
Status: COMPLETED
Conditions: Ductal Carcinoma in Situ
Interventions: DIETARY_SUPPLEMENT: Black cohosh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Stay Study: A Demonstration Project Advancing PrEP Delivery in the San Francisco Bay Area Transgender Community
Status: COMPLETED
Conditions: Transgender Persons|Pre-Exposure Prophylaxis
Interventions: DRUG: Emtricitabine / Tenofovir Disoproxil Oral Tablet|BEHAVIORAL: PrEP support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Scar-Improvement Efficacy and Safety of a Single Intradermal Injection of Avotermin (Juvista) Administered Following Full-Thickness Skin Incisions
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: Avotermin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Fluoxetine Capsules 40 mg and Prozac Pulvules 40 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fluoxetine Capsules 40 mg|DRUG: Prozac Pulvules 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioavailability Study Comparing 2 Vamifeport Oral Formulations in Fasted Versus Fed State in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Vamifeport Formulation 1|DRUG: Vamifeport Formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chronic Obstructive Pulmonary Disease (COPD)-Related Outcomes and Costs for Patients on Combination Fluticasone Propionate-Salmeterol Xinafoate 250/50mcg Versus Anticholinergics in a COPD-Comorbid Depression/Anxiety Population
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: fluticasone propionate/salmeterol xinafoate|DRUG: Anticholinergics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Food Supplements on Food Intake and Gut Hormone Levels
Status: COMPLETED
Conditions: Obesity|Endocrine; Obesity|Appetite; Perverted
Interventions: DIETARY_SUPPLEMENT: Lauric Acid, Perilla Oil and Diindolylmethane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Revlimid® and Low Dose Continuously Administered Melphalan to Treat High Risk MDS
Status: COMPLETED
Conditions: Myelodysplastic Syndromes|Leukemia, Myelomonocytic, Chronic|Angiogenesis
Interventions: DRUG: Lenalidomide and melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-CSF Moblized Peripheral Harvest for Poor Engraftment After Stem Cell Transplantation
Status: COMPLETED
Conditions: Poor Graft Function|Stem Cell Transplantation|Graft Versus Host Disease
Interventions: OTHER: infusion of G-CSF mobilized peripheral harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAHANCA 27 Transoral Laser Microsurgery for T1a Glottic Cancer
Status: UNKNOWN
Conditions: Head and Neck Squamous Cell Carcinoma|Glottic T1
Interventions: PROCEDURE: Transoral Laser Microsurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Determine the Effect of a Cobiotic Formulation on the Gastrointestinal Microbiome
Status: COMPLETED
Conditions: Pre Diabetic
Interventions: DRUG: Placebo|DRUG: NM504:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Effectiveness of the Immunotherapy Agents Rituximab or Mosunetuzumab in Patients With Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Status: RECRUITING
Conditions: Nodular Lymphocyte Predominant B-Cell Lymphoma|Recurrent Nodular Lymphocyte Predominant B-Cell Lymphoma|Refractory Nodular Lymphocyte Predominant B-Cell Lymphoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|BIOLOGICAL: Mosunetuzumab|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab and Hyaluronidase Human
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Erector Spinae Block Versus Interscalene Block for Shoulder Surgery
Status: UNKNOWN
Conditions: Pain, Acute|Opioid Use
Interventions: PROCEDURE: Cervical ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retraining Body and Brain to Conquer Compulsions
Status: COMPLETED
Conditions: Compulsive Behavior
Interventions: BEHAVIORAL: Physical Exercise|BEHAVIORAL: Stress management training A|BEHAVIORAL: Stress management training B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Descartes-15 for Patients With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Refractory Multiple Myeloma|Relapsed Multiple Myeloma
Interventions: DRUG: Descartes-15
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
Status: RECRUITING
Conditions: Preeclampsia|Hypertensive Disorder of Pregnancy|Toxemia|Pregnancy Complications|Hypertension, Pregnancy-Induced|Hypertension|Obesity|Overweight|Nutrition Disorders|Vascular Diseases|Cardiovascular Diseases|Pre-Eclampsia|Eclampsia|Gestational Hypertension
Interventions: BEHAVIORAL: Heart Health Doula Intervention Program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Plus Surgery in Treating Patients With Stage III or Stage IV Ovarian, Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Promoting Physical Growth and Positive Development in Severely Stunted Guatemalan Children
Status: COMPLETED
Conditions: Malnutrition|Developmental Disabilities
Interventions: BEHAVIORAL: Home-based nutrition education|DIETARY_SUPPLEMENT: Standard-of-care nutrition support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Tolerability of PBF-1650 in Healthy Volunteers.
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PBF-1650 oral capsules|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT