pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Learn About The Study Medicine (Called PF-06823859) in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: IFN-β inhibitor treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Dry Needling in People With Episodic Tension-type Headache
Status: NOT_YET_RECRUITING
Conditions: Episodic Tension-type Headache
Interventions: OTHER: dry needling|OTHER: sham (placebo) dry needling:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medium-term Health Coaching and Life-long Monitoring in Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: OTHER: Self-monitoring for patients with Diabetes mellitus type 2|OTHER: Nurse-monitoring for patients with Diabetes mellitus type 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Twitter Based Social Support for Hispanic and Black Dementia Caregivers
Status: ACTIVE_NOT_RECRUITING
Conditions: Loneliness|Emotional Stress
Interventions: BEHAVIORAL: Twitter for Hispanic caregivers|BEHAVIORAL: Twitter for African American caregivers
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Controlled Trial With Use of Cognitive Training in Children and Adolescents With ADHD
Status: UNKNOWN
Conditions: Attention-deficit/Hyperactivity Disorder.
Interventions: BEHAVIORAL: Cognitive training|BEHAVIORAL: Placebo cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
Status: COMPLETED
Conditions: Chronic Angle Closure Glaucoma|Primary Angle Closure|Primary Angle Closure Suspect|Fellow Eyes of Acute Angle Closure Glaucoma
Interventions: PROCEDURE: Q-switched fd Nd:yag in Laser Iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Safety and Effectiveness of RECELL for Repigmentation of Stable Vitiligo Lesions
Status: COMPLETED
Conditions: Vitiligo
Interventions: DEVICE: Control Intervention (UVB)|DEVICE: Investigational Interventions (Ablative Laser Resurfacing + RECELL + UVB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
Status: RECRUITING
Conditions: Histamine|Cowhage|Sleep Deprivation
Interventions: OTHER: Histamine|OTHER: Cowhage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Pharmacokinetics of SHC014748M in Patients With Indolent B-Cell Hematologic Malignancies
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)|B-Cell Non-Hodgkin Lymphomas(NHL)
Interventions: DRUG: SHC014748M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decision Aids to Improve Knowledge in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Internet-Based Intervention|OTHER: Internet-Based Intervention|OTHER: Best Practice|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Survey Administration|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy
Status: RECRUITING
Conditions: Renal Cell Carcinoma, Clear Cell, Somatic
Interventions: DRUG: Fruquintinib and Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Open Label
Status: ENROLLING_BY_INVITATION
Conditions: Autism Spectrum Disorder
Interventions: DRUG: N-acetylcysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention in Overweight Women
Status: COMPLETED
Conditions: Obesity|Weight Loss|Lifestyle, Sedentary|Physical Activity|Nutritional and Metabolic Disease|Behavior, Health|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Supervised exercise|BEHAVIORAL: Lifestyle intervention from baseline to 4 months|BEHAVIORAL: Monthly behavioral sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carbetocin vs. Oxytocin: In-vitro Myometrial Contractions With and Without Oxytocin Pre-treatment
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders
Status: UNKNOWN
Conditions: Post-Traumatic Stress Disorder|Overweight and Obesity|Metabolic Syndrome|Inflammation
Interventions: BEHAVIORAL: Mediterranean Diet & Physical Activity|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: FF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Attentional Strategies on Throwing Performance and Gaze Behavior of Self-paced Tasks Under Fatigue and Non-fatigue Conditions
Status: UNKNOWN
Conditions: Motor Learning
Interventions: BEHAVIORAL: Attentional focus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: High-definition Transcranial Electrical Stimulation for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: HD-tCES|DEVICE: Sham HD-tCES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
Status: COMPLETED
Conditions: Coronary Heart Disease|Cardiovascular Risk Factor|Arterial Stiffness|Blood Pressure|Sleep
Interventions: BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating the Efficacy and Safety of AV5080 in Patients With Uncomplicated Influenza
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: AV5080|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Pharyngeal Exerciser and Dysphagia
Status: RECRUITING
Conditions: Dysphagia
Interventions: DEVICE: Pharyngeal exerciser|DEVICE: sham pharyngeal exerciser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve Injury
Status: UNKNOWN
Conditions: Injury of Trigeminal Nerve|Surgery|Mandibular Prognathism
Interventions: BEHAVIORAL: sensory retraining protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Diabetes|Hyperlipidemia
Interventions: DRUG: Metformin + Rosuvastatin|DRUG: JLP-1310
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Relation Between Recurrence of Enterocutaneous Fistula and Preoperative C-reactive Protein Level After Complete Surgical Repair
Status: COMPLETED
Conditions: Enterocutaneous Fistula
Interventions: DIAGNOSTIC_TEST: serum C-reactive protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: School-Based Bladder Health Intervention
Status: WITHDRAWN
Conditions: Urinary Dysfunction|Lower Urinary Tract Symptoms|Urinary Tract Infections|Urinary Tract Infections in Children
Interventions: BEHAVIORAL: Bladder Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of a Comprehensive Cardiac Rehabilitation Program Framework Among High Cardiovascular Risk Cancer Survivors
Status: COMPLETED
Conditions: Oncologic Disorders|Cardiovascular Diseases
Interventions: OTHER: Cardiac Rehabilitation Program|OTHER: Community exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of SAR 1118 to Treat Dry Eye Conducted in a Controlled Adverse Environment (CAE) (OPUS-1)
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Dry Eye Disease
Interventions: DRUG: Lifitegrast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dual Energy Catheter (PFA and RFA) and a PFA Catheter for the Treatment of PeAF
Status: RECRUITING
Conditions: Persistent Atrial Fibrillation
Interventions: OTHER: a dual energy catheter (RF and PFA) or PFA catheter only will be to treat PeAF,Cardiac Pulsed Electric Field Ablation Catheter|OTHER: catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Criteria for Selecting Patients for Primary Prevention of Sudden Cardiac Death by Arrhythmic Risk Stratification
Status: RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: ICD implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TMB-365 and TMB-380 in Suppressed HIV-1 Infected Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: TMB-365/TMB-380
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Boosting the HRQoL Among HIV+ Mothers and Children
Status: RECRUITING
Conditions: HIV|Perinatal HIV Infection
Interventions: BEHAVIORAL: Resilience intervention|BEHAVIORAL: Adherence intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The BLIMP Balloon in Coronary Interventions
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention|Chronic Total Occlusion of Coronary Artery
Interventions: DEVICE: BLIMP balloon|DEVICE: Low profile balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Respiratory Mechanics on Brain-specific Monitoring in Brain-injured Patients
Status: WITHDRAWN
Conditions: Brain Injuries
Interventions: OTHER: PEEP level 5 cmH2O|OTHER: PEEP level 15 cmH2O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Role of Theophylline Plus Low-dose Formoterol-budesonide in Treatment of Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: Formoterol-budesonide|DRUG: Theophylline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Heme Arginate With or Without Tin Mesoporphyrin in Patients With Acute Attacks of Porphyria
Status: COMPLETED
Conditions: Porphyria
Interventions: DRUG: heme arginate|DRUG: tin mesoporphyrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MC2-25 Cream in Subjects wITh CHronic KIdNEy Disease-aSsociated prurituS (ITCHINESS) Trial
Status: COMPLETED
Conditions: Chronic Kidney Disease-associated Pruritus
Interventions: DRUG: MC2-25 cream|DRUG: MC2-25 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Performance of the ID Now™ COVID-19 Screening Test Versus Simplexa™ COVID-19 Direct Assay
Status: COMPLETED
Conditions: Covid19
Interventions: DIAGNOSTIC_TEST: ID Now™ COVID-19 Screening Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Left Bundle Branch Pacing Versus Conventional Pacing in Atrioventricular Block
Status: COMPLETED
Conditions: Atrioventricular Nodal Disease
Interventions: DEVICE: Left bundle branch pacing lead (Select Secure 3830 lead)|DEVICE: Right ventricular active fixation lead
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Simplified Modified Atkins Diet in Children With Refractory Epilepsy
Status: COMPLETED
Conditions: Refractory Epilepsy
Interventions: OTHER: Simplified Modified Atkins Diet|DRUG: Antiepileptic drugs alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: DRUG: Placebo|DRUG: Fulranumab 1 mg|DRUG: Fulranumab 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Help-seeking Intentions of ROTC Trainees
Status: UNKNOWN
Conditions: Help-Seeking Behavior|Musculoskeletal Injury
Interventions: OTHER: Authority-delivered Health promotion video|OTHER: Peer-delivered Health Promotion Video|OTHER: Control Group Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Nicotinic Acid on Cardiovascular Risks Indices in Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: tredaptive (nicotinic acid/ laropiprant)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy in LPL-Deficient Subjects of AMT-011, an Adeno-Associated Viral Vector Expressing Human Lipoprotein Lipase [S447X]
Status: UNKNOWN
Conditions: Familial Lipoprotein Lipase Deficiency
Interventions: GENETIC: Alipogene Tiparvovec (AMT-011), Human LPL [S447X]|DRUG: Mycophenolate mofetil|GENETIC: Alipogene Tiparvovec (AMT-011), Human LPL [S447X]|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Substitution on the Development of Chronic Pancreatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pancreatitis
Interventions: DIETARY_SUPPLEMENT: Vitamin D 100ug|DIETARY_SUPPLEMENT: Vitamin D 10ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae
Status: UNKNOWN
Conditions: Bloodstream Infection
Interventions: DRUG: Monotherapy and combination therapy (all antibiotics that are given by attending pysicians and can be active against Klebsiella pneumoniae will be evaluated)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple Rising Dose Study of BI 144807 Powder in Bottle in Mild Asthmatic Patients
Status: COMPLETED
Conditions: Healthy|Asthma
Interventions: DRUG: Placebo to BI 144807|DRUG: BI 144807
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare LY09004 and Eylea in the Treatment of Wet Age-related Macular Degeneration（wAMD）
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: LY09004|DRUG: Eylea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Convex Probe EBUS-TBNA Versus FDG-PET/CT Imaging in Diagnosis and Staging of Lung Malignancies
Status: COMPLETED
Conditions: Lung Malignancies|Mediastinal Lymphadenopathy
Interventions: DIAGNOSTIC_TEST: Endo bronchial ultrasound transbronchial needle aspiration(EBUS-TBNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Potential Predictors of Disease Progression in Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Including Genetics, Biomarkers, and Treatment
Status: TERMINATED
Conditions: Atypical Hemolytic Uremic Syndrome
Interventions: OTHER: Eculizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnesium Replacement Therapy to Prevent Acute Renal Failure in Critically Ill Patients
Status: COMPLETED
Conditions: Hypomagnesemia
Interventions: DRUG: Magnesium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective Study of Breast Cancer Patients With Abnormal Strain Imaging
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2 Positive Breast Cancer|Cardiovascular Abnormalities
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Intensive Inpatient Attending Supervision on Medical Errors, Patient Safety and Resident Education
Status: COMPLETED
Conditions: Focus of Study is on Graduate Medical Education Supervision
Interventions: OTHER: Enhanged Attending Supervision|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BELOVA Data Collection: Safety and Efficacy of Frontline Bevacizumab Treatment in Participants With Ovarian Cancer 70 Years and Older
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective Study: Alveolar Ridge Augmentation Using Tenting Screws, Acellular Dermal Matrix and Combination Particulate Grafts
Status: COMPLETED
Conditions: Dental Alveolus|Oral Surgical Procedures, Preprosthetic
Interventions: DEVICE: allograft alone|DEVICE: allograft with autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Footbaths With Ginger, Mustard & Warm Water Only in Female Adolescents With & Without Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: OTHER: Warm water|OTHER: Mustard|OTHER: Ginger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2B Open-Label, Single-Arm, Repeat-Dose Study to Evaluate the Reliability of an Autoinjector
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DEVICE: Belimumab autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 6 to 16 Years.
Status: COMPLETED
Conditions: Tick-borne Encephalitis
Interventions: BIOLOGICAL: Tick-borne encephalitis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Wearable Technology and Alcohol-Facilitated Intimate Partner Violence
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Abuse|IPV|Couples
Interventions: DEVICE: Heart Rate Variability-Biofeedback (HRV-B) via Smartwatch Device Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Development and Improvement of an Acceptance and Commitment-based Treatment for the Prevention of Chronic Pain After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Acceptance and Commitment-based treatment|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary Syndrome
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Indobufen|DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 12 Weeks in Adults With Chronic Genotype 2 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Energy Density and Information on Meal Intake in Adults
Status: TERMINATED
Conditions: Feeding Behavior
Interventions: OTHER: Lower Energy Density|OTHER: Higher Energy Density|OTHER: Lower Satiation|OTHER: Higher Satiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Bio-equivalence Study of Sofosbuvir From Elbanovir 400 mg Film Coated Tablets ( Multi-Apex Pharma, Egypt) & Sovaldi 400 mg Film Coated Tablets (Gilead Sciences, United Kingdom)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Elbanovir|DRUG: Sovaldi|DRUG: Sovaldi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Early Diagnosis of Patients With Mild Cognitive Impairment Through the Parameterization of Functional Tests.
Status: WITHDRAWN
Conditions: Mild Cognitive Impairment
Interventions: PROCEDURE: Standard Care or Usual Clinical Practice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Pharmacodynamic Effect of Single Doses of AZD9977 in Healthy Male Subjects
Status: COMPLETED
Conditions: Pharmacodynamics|Healthy Subjects
Interventions: DRUG: AZD9977 oral suspension|DRUG: AZD9977 placebo oral suspension|DRUG: Fludrocortisone, tablets|DRUG: Eplerenone, tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Intensity Interval Gait Training in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis,Gait, Exercise
Interventions: BEHAVIORAL: Moderate paced continuous gait training|BEHAVIORAL: High Intensity Interval gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroids In Eosinophil Negative Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mometasone 220mcg BID|DRUG: Tiotropium Respimat 5mcg QD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonsteroidal Antiinflammatory Drugs in Women With Postpartum Pre-eclampsia
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Ibuprofen|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remifentanil for General Anesthesia in the Context of Immaturity
Status: UNKNOWN
Conditions: Cesarean Section|Anesthesia
Interventions: DRUG: Remifentanil|DRUG: sodium chloride 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Roxadustat Conversion in Participants Receiving Stable Erythropoiesis-Stimulating Agent (ESA) or as Initial Anemia Treatment in Chronic Dialysis Participants
Status: COMPLETED
Conditions: Anemia Associated With End Stage Renal Disease (ESRD)
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphate Binder-combination Study of KHK7791 in Hyperphosphatemia Patients on Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: KHK7791|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Body Stabilization Exercises on Balance, Functional Performance and Lumbar Lordosis Angle in Patients With Total Knee Prosthesis
Status: UNKNOWN
Conditions: Arthroplasty, Replacement, Knee
Interventions: OTHER: Conservative Physical Therapy|OTHER: Body Stabilization Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation
Status: RECRUITING
Conditions: Cervical Spinal Cord Injury|Tetraplegia
Interventions: DEVICE: ARC-BSI Cervical system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skeletal Muscle Lipid and Insulin Resistance: Effects of Physical Activity and Weight Loss
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Weight Loss|BEHAVIORAL: Exercise and weight loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subcutaneous Alemtuzumab (CAMPATH®, MabCampath®) in Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia (B-CLL)
Interventions: BIOLOGICAL: Alemtuzumab|BIOLOGICAL: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction
Status: RECRUITING
Conditions: Lower Urinary Tract Obstructive Syndrome|Lower Urinary Tract Obstruction, Congenital|Bladder Outlet Obstruction|Bladder Outflow Obstruction
Interventions: DEVICE: Fetoscopes|PROCEDURE: Fetal Cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Fluconazole Treatment of Premature and Full-term Newborn Infants
Status: COMPLETED
Conditions: Ductus Arteriosis, Patent|Bacterial Infections and Mycoses
Interventions: DRUG: Treatment with fluconazole.|DRUG: 2. Treatment with both fluconazole and Ibuprofen.|DRUG: 3. Treatment with ibuprofen.|OTHER: 4. No treatment with either fluconazole nor ibuprofen.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma
Status: COMPLETED
Conditions: Raynaud's Phenomenon|Digital Ulcers|Scleroderma
Interventions: DRUG: Tadalafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prediction of the Response to Chemotherapy by Tomoscintigraphie the MIBI in the Balance Sheet Pre Hodgkin's Disease and Lymphoma Malins High Grade
Status: COMPLETED
Conditions: Hodgkin's Disease|Malignant Lymphomas High Grade|Chemoresistance
Interventions: PROCEDURE: TEP au MIBI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-step Antigen Loading and TLR Activation of Dendritic Cells in Melanoma Patients
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: autologous dendritic cell vaccine|BIOLOGICAL: autologous dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period.
Status: SUSPENDED
Conditions: Cerebral Infarction
Interventions: BIOLOGICAL: Allogeneic umbilical cord mesenchymal stem cell|DRUG: Aspirin Enteric-coated Tablets & Atorvastatin Calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ruxolitinib and Steroid as First Line Therapy for Acute GVHD
Status: UNKNOWN
Conditions: Acute GVHD
Interventions: DRUG: Ruxolitinib Oral Tablet|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Remission Evaluation Before Intensified Treatment in Lymphoma: Impact of Positron Emission Tomography (PET) Using Fluorine-18-Floro-Deoxyglucose (FDG) in the Therapeutic Prescription. Medico-Economic Randomised Study
Status: UNKNOWN
Conditions: Lymphoma
Interventions: PROCEDURE: positron emission tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic|Lupus Nephritis
Interventions: BIOLOGICAL: rapcabtagene autoleucel Regimen 1|BIOLOGICAL: rapcabtagene autoleucel Regimen 2|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
Status: NOT_YET_RECRUITING
Conditions: Difficult to Control Hypertension
Interventions: DRUG: MANP|OTHER: Placebo Matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Comparing Periodic Acceleration Versus Static Position in Cerebrovascular Stroke Patients
Status: WITHDRAWN
Conditions: Cerebrovascular Stroke
Interventions: DEVICE: Exer-Rest® TL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery.
Status: RECRUITING
Conditions: Colorectal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Oral Impact|DIETARY_SUPPLEMENT: Nutren Optimum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Different Anesthetic Techniques for Isolated Systolic Hypertensive Patients of Abdominal Surgery on Postoperative Hospital Stay and Morbidity
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: remifentanil(Ultiva)|DRUG: epidural infusing 2% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Prevelance Rate of Human Cytomegalovirus (HCMV), Epstein-Barr Virus (EBV) and Human Herpes Virus (HHV-6) in a Saliva of the Patient With Periodantitis
Status: UNKNOWN
Conditions: Cytomegalovirus|Epstein-Barr Virus Infections|Herpesvirus Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy Plus Gadolinium Texaphyrin in Treating Patients With Cancer of the Pancreas That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: motexafin gadolinium|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds
Status: RECRUITING
Conditions: Sarcoma|Cancer|Infectious Disease
Interventions: DEVICE: Prevana Dressing|OTHER: Standard Dry Gauze Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Immediate Implant Placement Using Dual Zone Approach Versus Connective Tissue Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: Immediate Dental Implants
Interventions: PROCEDURE: immediate implant placement with particulate bone graft using the dual zone technique.|PROCEDURE: immediate implant placement with connective tissue grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brain Stimulation for the Treatment of Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DEVICE: NeuroPace RNS® System Deep Brain Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intraoperative Esmolol to Improve Postoperative Quality of Recovery and Pain After Ambulatory Surgery
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Esmolol administered at a rate of 0.5 mg/kg followed by an infusion of 5-15 mcg/kg/min|DRUG: Placebo Comparator: .9 normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Staging LaParoscopy to Assess Lymph NOde InvoLvement in Advanced GAstric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Lymph Node Metastasis
Interventions: PROCEDURE: Sentinel Node Assessment|PROCEDURE: Staging laparoscopy|PROCEDURE: Gastroscopy with indocyanine green (ICG) injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Investigation of the Effects of Erythromycin on the Pharmacokinetics of the Pregabalin Controlled Release Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pregabalin controlled release, 330 mg|DRUG: Pregabalin controlled release, 330 mg|DRUG: erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of High Voltage Electrical Stimulation, Shortwave Diathermy and Kinesiotherapy on Arterial Blood Flow in the Lower Limbs of Diabetic Women
Status: COMPLETED
Conditions: Diabetes|Peripheral Arterial Disease
Interventions: OTHER: high-voltage electrical stimulation|OTHER: Kinesiotherapy|OTHER: shortwave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive Dyskinesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Major Depressive Disorder|Tardive Dyskinesia
Interventions: DRUG: Valbenazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Fourth Left Atrial Appendage Occlusion Study
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke, Ischemic|Systemic Embolism
Interventions: DEVICE: WATCHMAN device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab/Vibostolimab|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Pemetrexed|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EVA3S: Endarterectomy Versus Angioplasty in Patients With Severe Symptomatic Carotid Stenosis
Status: COMPLETED
Conditions: Transient Ischemic Attack|Carotid Stenosis|Atherosclerosis
Interventions: DEVICE: Carotid angioplasty and stenting with cerebral protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influence of Glitazones on the Vasodilatory Effect of High-density Lipoprotein (HDL) Lipoproteins
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: pioglitazone|DRUG: rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Depression
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Adipose-derived Stem Cells (ASC) in Patient With Critical Limb Ischemia.
Status: TERMINATED
Conditions: Critical Limb Ischemia and Peripheral Artery Disease
Interventions: DRUG: Autologous ASC (for Adipose-derived Stem/Stroma Cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Orange Juice and Glycaemic Control in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: orange juice concentrate|OTHER: Sugar-sweetened orange-flavoured beverage|OTHER: Whole orange juice with skin removed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Omarigliptin & Trelagliptin in Twelve Healthy Egyptian Volunteers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Omarigliptin 25 mg|DRUG: Trelagliptin 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Propofol Versus Sevoflurane on Incidence of Postoperative Delirium in Elderly Patients After Spine Surgery
Status: RECRUITING
Conditions: Delirium in Old Age|Anaesthetic
Interventions: DRUG: propofol infusion|DRUG: sevoflurane inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Lenalidomide as a Treatment for Recurrent or Refractory POEMS Syndrome Trial
Status: COMPLETED
Conditions: POEMS Syndrome
Interventions: DRUG: Lenalidomide+Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of SHR-1210 in Combination With SHR6390 in Patients With Advanced CRC, NSCLC and HCC
Status: UNKNOWN
Conditions: CRC|HCC|NSCLC
Interventions: DRUG: SHR-1210|DRUG: SHR6390
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abatacept for Patients With Inflammatory Arthritis Associated With Sjögren's Syndrome: an Open-Label Phase II Study
Status: WITHDRAWN
Conditions: Primary Sjogren's Syndrome|Secondary Sjogren's Syndrome|Inflammatory Arthritis|Rheumatoid Arthritis
Interventions: DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effect of High Altitudes on Physiological and Metabolic Markers in Adults Living at Qinghai-Tibet Plateau for Work Purpose
Status: UNKNOWN
Conditions: Residence or Prolonged Visit at High Altitude as the Cause of Mountain Sickness
Interventions: OTHER: Chronic hypoxic environment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
Status: RECRUITING
Conditions: Sickle Cell Disease|Thalassemia|Hemoglobinopathy
Interventions: BIOLOGICAL: Biotin-labeled red blood cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of NICOtinic Acid (Niacin) on Elevated Lipoprotein(a) Levels (NICOLa Study)
Status: UNKNOWN
Conditions: Elevated Lipoprotein(a) Levels
Interventions: DRUG: Nicotinic acid (niacin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority of Various GSK Bio's Influenza Vaccine Presentations in Adults Aged 65 Years and Over
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: GSK Bio's influenza vaccine GSK576389A [NH 2006/07 season]|BIOLOGICAL: GSK Bio's influenza vaccine GSK576389A [NH 2007/08 season]|BIOLOGICAL: Fluarix [NH 2006/07 season]|BIOLOGICAL: Fluarix [NH 2007/08 season]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BR790 in Combination With Anlotinib in Adult Subjects With Advanced Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: BR790+anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postpartum Care in the NICU (PeliCaN) Transitions
Status: NOT_YET_RECRUITING
Conditions: Stress Disorders, Post-Traumatic|Premature Birth|Postpartum Depression|Postpartum Anxiety
Interventions: OTHER: Doula Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GF-GS 01: Comparing Conventional Axillary Dissection Versus Sentinel Node Resection in Clinically Node-negative Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Sentinel Node Resection|PROCEDURE: Conventional Axillary Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhanced Recovery After Surgery (ERAS) Pathway for Primary Hip and Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip, Knee
Interventions: PROCEDURE: The ERAS group|PROCEDURE: The non-ERAS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine (AZA) in Minimal Residual Disease (MRD) Chronic Myeloid Leukemia (CML)
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Azacitidine (AZA)|DRUG: Tyrosine kinase inhibitor (TKI)|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT