pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Electronic Patient Notification of Remote ICD Data: Impact of Patient Engagement on Outcomes in the Merlin.Net™
Status: COMPLETED
Conditions: Implantable Cardioverter-Defibrillator|Health Information Exchange|Electronic Health Records|Patient Participation
Interventions: OTHER: Receive Detailed ICD Information-electronic|OTHER: Receive Detailed ICD Information-paper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Safety and Feasibility of Diamyd® in Individuals at Risk for Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1|Autoimmune Diseases|Prevention
Interventions: DRUG: Diamyd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Chronic Pain After Groin Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal|Hernia, Femoral
Interventions: PROCEDURE: Totally ExtraPeritoneal (TEP) repair|PROCEDURE: TransAbdominal PrePeritoneal (TAPP) repair|PROCEDURE: Open anterior mesh repair|PROCEDURE: Open Anterior Non Mesh|PROCEDURE: Combined anterior and posterior repair|PROCEDURE: Open preperitoneal mesh repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MK0767 in Metabolic Syndrome-Dyslipidemia (0767-016)
Status: TERMINATED
Conditions: Metabolic X Syndrome Dyslipidemia
Interventions: DRUG: MK0767|DRUG: Comparator: fenofibrate|DRUG: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: POEM Versus Pneumatic Dilatation in Achalasia Cardia
Status: UNKNOWN
Conditions: Achalasia Cardia
Interventions: PROCEDURE: Per Oral Endoscopic Myotomy (POEM)|PROCEDURE: Pneumatic Dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Endoscopic Thyroidectomy Via Retro-Auricular Single-Site Approach, Transoral Approach and Transareola
Status: RECRUITING
Conditions: Papillary Thyroid Carcinoma
Interventions: PROCEDURE: Retro-Auricular Single-Site Endoscopic Thyroidectomy|PROCEDURE: Transoral Endoscopic Thyroidectomy Vestibular Approach|PROCEDURE: Transareola Endoscopic Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males With Klinefelter Syndrome
Status: RECRUITING
Conditions: Klinefelter Syndrome
Interventions: DRUG: Fenofibrate 145 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance
Status: UNKNOWN
Conditions: Hyperinsulinism|Insulin Resistance|Insulin Sensitivity|Glucose Intolerance|Hypertension
Interventions: DRUG: Vigabatrin Pill|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Stevia Rebaudiana Extracts on Different Variables Related to Caries: an in Vitro and in Vivo Evaluation.
Status: COMPLETED
Conditions: Dental Caries
Interventions: DIETARY_SUPPLEMENT: Effect of Stevioside and Rebaudioside on plaque pH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: WallFlex Biliary Fully Covered (FC) Benign Stricture Study
Status: COMPLETED
Conditions: Biliary Stricture
Interventions: DEVICE: WallFlex Biliary RX Fully Covered Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Response Rate of PROCRIT (Epoetin Alfa) Given at a Dose of 40,000 Units Once a Week to Cancer Patients With Anemia Who Are Not Receiving Chemotherapy.
Status: TERMINATED
Conditions: Anemia|Neoplasms
Interventions: DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdermal Lidocaine Administration Prior to Insertion Levonorgestrel-releasing Intrauterine System
Status: UNKNOWN
Conditions: IUCD Complication
Interventions: DRUG: lidocaine patch|DRUG: Sham patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study With Different Tracers (18F-FDG and 68Gallium Citrate) in the Diagnosis of Periprosthetic Joint Infection
Status: UNKNOWN
Conditions: Infection and Inflammatory Reaction Due to Internal Joint Prosthesis
Interventions: OTHER: 68Ga-citrate and 18F-FDG PET scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of DM005 in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Squamous Cell Carcinoma of Head and Neck|Solid Carcinoma
Interventions: DRUG: DM005
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing Gastric Cancer [DESTINY-Gastric01]
Status: COMPLETED
Conditions: Neoplasm, Gastrointestinal
Interventions: DRUG: DS-8201a|DRUG: Physician's Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Fatiguability in Older Adults: The Protective Effects of Dietary Nitrate Supplementation
Status: UNKNOWN
Conditions: Aging
Interventions: DIETARY_SUPPLEMENT: Beetroot Juice|OTHER: Placebo Beetroot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Learn About New COVD-19 RNA Vaccine Candidates for New Variants in Healthy Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: BIOLOGICAL: BNT162b2 (Omi XBB.1.5)|BIOLOGICAL: BNT162b2 (Omi JN.1)|BIOLOGICAL: BNT162b2 "(2024-2025 variant)"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home Exercises Program Compared With Physiotherapy Program in TMD
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: OTHER: Intervention Group: Physiotherapy program + home exercises program|OTHER: Control Group : Physiotherapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Tadalafil|DRUG: Placebo|DRUG: ERA as specific PAH treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease
Status: COMPLETED
Conditions: LVM|Type 2 Diabetic Patients With IHD|Endothelial Function
Interventions: DRUG: pioglitazone group|DRUG: Metformin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Pembrolizumab (MK-3475) in Chinese Participants With Non-Small-Cell Lung Cancer (MK-3475-032/KEYNOTE-032)
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Adenocarcinoma|Stage IV
Interventions: DRUG: Rigosertib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Comparison of Salivary Fluoride Levels Following the Application of Different 5% NaF Varnishes
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Enamel Pro|DEVICE: Duraphat|DEVICE: Vanish|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study of Peginterferon Lambda-1a and Ribavirin With Telaprevir
Status: COMPLETED
Conditions: Hepatitis C Virus
Interventions: BIOLOGICAL: Peginterferon Lambda-1a|BIOLOGICAL: Peginterferon Alfa-2a|DRUG: Ribavirin|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene
Status: ACTIVE_NOT_RECRUITING
Conditions: Confirmed Diagnosis of ß-thalassemia Major
Interventions: GENETIC: Autologous CD34+ cells transduced with TNS9.3.55
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of the Effect of Preoperative Forced-air Warming on Perioperative Body Temperature Following Neuraxial Anesthesia in Total Hip Arthroplasty Patients
Status: TERMINATED
Conditions: Perioperative Hypothermia
Interventions: DEVICE: Bair-Paws Warming Device|DEVICE: Bair-Hugger Warming Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on the Prevention of Emergence Agitation in Children Undergoing Day Surgery
Status: COMPLETED
Conditions: Ambulatory Surgical Procedures
Interventions: DRUG: 0.2ug/kg dexmedetomidine|DRUG: 0.4ug/kg dexmedetomidine|DRUG: 0.6ug/kg dexmedetomidine|DRUG: 0.8ug/kg dexmedetomidine|DRUG: 1.0ug/kg dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
Status: COMPLETED
Conditions: Askin Tumor|Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor|Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequenced Treatment Effectiveness for Posttraumatic Stress
Status: ACTIVE_NOT_RECRUITING
Conditions: PTSD
Interventions: DRUG: Selective serotonin reuptake inhibitor|DRUG: Serotonin-norepinephrine reuptake inhibitor|BEHAVIORAL: Written Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HepaRAS Trial: Changes in Hepatectomy Risk Assessment When Using Mebrofenin HIDA
Status: WITHDRAWN
Conditions: Liver Failure as A Complication of Care|30-day Mortality
Interventions: DIAGNOSTIC_TEST: mHBS|DIAGNOSTIC_TEST: CT/MRI volumetry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Regorafenib Alone or in Combination With High/Low-dose Radiotherapy Plus Toripalimab for Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Microsatellite Stable Metastatic Colorectal Cancer
Interventions: DRUG: Regorafenib|DRUG: Toripalimab|RADIATION: High/low-dose radiotherapy|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nurse-led Psycho-education Program for People With First-onset Mental Illness (APN-PEP)
Status: COMPLETED
Conditions: Mental Illness
Interventions: BEHAVIORAL: Nurse-led Psycho-education (or SPBB: self-learning program)|BEHAVIORAL: Usual Psychiatric Outpatient Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare the Efficacy and Safety of Lisocabtagene Maraleucel vs Investigator's Choice Options in Adult Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, Whose Disease Has Failed Treatment With Both BTKi and BCL2i Therapies
Status: WITHDRAWN
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: BIOLOGICAL: Liso-cel|DRUG: Idelalisib|DRUG: Rituximab|DRUG: Bendamustine|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC
Status: RECRUITING
Conditions: Nanoliposomal Irinotecan|Cadonilimab|Oxaliplatin|Capecitabine|First-Line|Advanced Cancer|Pancreatic Adenocarcinoma|Drug Use
Interventions: DRUG: Nanoliposomal Irinotecan+Oxaliplatin +Capecitabine+Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DAIR for Infected Total Hip Arthroplasty - Does the Operative Approach Influence the Functional Result?
Status: COMPLETED
Conditions: Hip Prosthesis Infection|Arthroplasty Complications
Interventions: PROCEDURE: Transgluteal approach to the hip joint|PROCEDURE: Posterior approach to the hip joint
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Health Information Technology to Improve Health Behaviors and Promote Cardiovascular Health Among Adolescent and Young Adult Cancer Survivors
Status: COMPLETED
Conditions: Cardiovascular Disease|Young Adult Cancer Survivors
Interventions: BEHAVIORAL: Wait-List Control|BEHAVIORAL: PREVENT tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: System-Wide Improvement for Transitions After Surgery: The SWIFT Post op Program
Status: COMPLETED
Conditions: Colectomy|Colorectal Surgery|Ileostomy
Interventions: BEHAVIORAL: compliance surveillance and improvement strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Controlled, Randomized, Four-arm Comparative, Open Label, Multi-centric Clinical Trial to Compare the Efficacy and Safety Parameters of the Once-a-week or Once-a-month Administered 7000 IU, or 30000 IU Vitamin D (Cholecalciferol) to a 1000 IU Dosage Applied Daily in Vitamin D Deficient Patients
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation in Systemic Lupus Erythematosus
Status: WITHDRAWN
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Allogeneic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dairy Products on Insulin Resistance
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Sensitivity|Glucose Intolerance|PreDiabetes
Interventions: OTHER: Reduced fat dairy|OTHER: Regular fat dairy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AMG 102, Pemetrexed Disodium, and Cisplatin in Treating Patients With Malignant Pleural Mesothelioma
Status: WITHDRAWN
Conditions: Advanced Malignant Mesothelioma|Epithelial Mesothelioma|Recurrent Malignant Mesothelioma|Sarcomatous Mesothelioma
Interventions: BIOLOGICAL: rilotumumab|DRUG: cisplatin|DRUG: pemetrexed disodium|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemoradiotherapy Followed by PD-1 Inhibitor in Advanced Cervical Cancer
Status: RECRUITING
Conditions: Locally Advanced Cervical Carcinoma|Concurrent Chemoradiotherapy|Immunotherapy
Interventions: DRUG: Albumin-Bound Paclitaxel, cisplatin, Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambien CR vs. Placebo For Treatment Of Insomnia Associated With Anxiety When Used Concomitantly With Escitalopram (Lexapro)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: zolpidem tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Angel™ Catheter in Subjects With Risk of Pulmonary Embolism
Status: COMPLETED
Conditions: Pulmonary Embolism|Deep Vein Thrombosis|Venous Thromboembolism
Interventions: DEVICE: Angel Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter, Randomized Placebo-controlled Clinical Trial to Evaluate the Effect of Perioperative Use of Tranexamic Acid on Transfusion Requirements and Surgical Bleeding in Major Spine Surgery
Status: COMPLETED
Conditions: Spinal Fusion|Antifibrinolytic Agents|Hemorrhage|Blood Transfusion
Interventions: DRUG: Tranexamic Acid|DRUG: fisiologic serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Polyaxial Locking Plates in Treating Distal Humeral Fractures
Status: COMPLETED
Conditions: Distal Humerus Fracture
Interventions: PROCEDURE: Medartis|PROCEDURE: Synthes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Right Ventricular Lead Placement in a Pacemaker Population: Evaluation of Apical and Alternative Position
Status: UNKNOWN
Conditions: Bradycardia|Heart Block|Sick Sinus Syndrome
Interventions: PROCEDURE: Permanent Cardiac Pacemaker Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pharmacokinetic Study of Levodopa and Carbidopa Intestinal Gel in Subjects With Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Levodopa-Carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of the Safety, Pharmacokinetics and Antiretroviral Activity of 10-1074
Status: COMPLETED
Conditions: Healthy|HIV
Interventions: BIOLOGICAL: 3 mg/kg, single dose IV administration of 10-1074|BIOLOGICAL: 10 mg/kg, single dose IV administration of 10-1074|BIOLOGICAL: 30 mg/kg, single dose IV administration of 10-1074
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Study of Trop2 CAR-NK in the Treatment of Relapsed/Refractory Non-Small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer NSCLC
Interventions: BIOLOGICAL: Anti-Trop2 CAR-NK cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact Of A Tele-Exercise Program For Children With Cystic Fibrosis During The Covid-19 Pandemic On Quality Of Life
Status: COMPLETED
Conditions: Cystic Fibrosis|Exercise Addiction|Nursing Caries|Quality of Life|Exercise Adherence
Interventions: BEHAVIORAL: Tele-Exercise Program|BEHAVIORAL: Just observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks
Status: RECRUITING
Conditions: Metabolic Health
Interventions: OTHER: Whole Room Calorimeter|OTHER: Mixed-Meal Tolerance Test (MMTT)|OTHER: Core Body Temperature|OTHER: Morningness-Eveningness Questionnaire|PROCEDURE: Muscle Biopsy|OTHER: Serial Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I/Ib Multiple Ascending Dose Study in China
Status: COMPLETED
Conditions: Metastatic Solid Tumors
Interventions: DRUG: Avelumab 3 mg/kg Q2W|DRUG: Avelumab 10 mg/kg Q2W|DRUG: Avelumab 20 mg/kg Q2W|DRUG: Avelumab 10 mg/kg QW
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehabilitative Efficacy of a Visual Feedback Device for Locomotion of Post-stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Copernicus noVF|DEVICE: Copernicis VF-Plus|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study Between AZD3355 and Nexium
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AZD3355|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effect of ITCA 650 on the PK/PD of Oral Contraceptive in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy Adult Premenopausal Female Volunteers
Interventions: DRUG: ITCA 650 20/60 mcg/day, ITCA placebo|DRUG: ITCA placebo, ITCA 650 20/60 mcg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Efficacy, Safety, and Tolerability of LYS006, in Patients With Mild to Moderate Ulcerative Colitis
Status: TERMINATED
Conditions: Colitis, Ulcerative
Interventions: DRUG: LYS006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S-Equol on Men With Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: S-equol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Allogenic Stem Cell Transplantation in Patients With High Risk CD33+ AML/MDS/JMML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Gemtuzumab Ozogamicin|DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Thymoglobulin|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia
Status: RECRUITING
Conditions: Infectious Pneumonia|Severe COVID-19
Interventions: DRUG: Reparixin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cataract Surgery and Inflammation - the Role for Preoperative NSAIDs (Pre-CIN)
Status: RECRUITING
Conditions: Cataract Surgery
Interventions: DRUG: Nepafenac Ophthalmic|DRUG: Nepafenac Ophthalmic|DRUG: Dexamethasone Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules in Healthy Adults
Status: COMPLETED
Conditions: Gastric Retention|Healthy
Interventions: DRUG: Formulation A|DRUG: Formulation B|DRUG: Formulation C|DRUG: Formulation D|DRUG: Formulation E|PROCEDURE: Endoscopy|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Palmitoleic Isomer Study
Status: COMPLETED
Conditions: Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Trans-C16:1 supplement|DIETARY_SUPPLEMENT: Cis-C16:1 supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Laser Therapy on Controlling Pain During Orthondontic Treatment
Status: UNKNOWN
Conditions: Malocclusion
Interventions: DEVICE: Laser|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure
Status: UNKNOWN
Conditions: Elevated Intraocular Pressure
Interventions: DRUG: Latanoprost ophthalmic solution, 0.005%|DRUG: TC-002 latanoprost ophthalmic solution, 0.005%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping Efficacy in Chronic Low Back Pain Treatment (KITALO)
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: Kinesio Taping method|DEVICE: Kinesio Taping sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Usability of HPV Vaccine Reminders
Status: COMPLETED
Conditions: Human Papilloma Virus (HPV)
Interventions: BEHAVIORAL: Text Message|BEHAVIORAL: PostCard|BEHAVIORAL: Standard of Care|BEHAVIORAL: Motivational Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Milk and Banana as a Night Meal to Primary Insomnia on Sleep Quality, BDNF and Appetite Mechanism
Status: COMPLETED
Conditions: Primary Insomnia
Interventions: BEHAVIORAL: Banana arm|BEHAVIORAL: Milk arm|BEHAVIORAL: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Treatment for Acute Ankle Sprains: Softcast Wrap Versus MOKcast
Status: COMPLETED
Conditions: Acute Ankle Sprain|Ankle Ligament Rupture|Ankle Injuries
Interventions: OTHER: Functional treatment for ankle sprain using ankle cast|OTHER: Ankle sprain treated with removable ankle support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Impact of Dexmedetomidine on Breast Cancer Recurrence After Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tension-free Vaginal Tape (TVT) Versus Bulking Agent for the Treatment of Post Vulvectomy Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: PROCEDURE: Tension free vaginal tape|PROCEDURE: Bulking agent injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dialectical Behavior Therapy (DBT) for Adolescents With Bipolar Disorder
Status: COMPLETED
Conditions: Dialectical Behavior Therapy + Pharmacotherapy|Standard of Care Psychotherapy + Pharmacotherapy
Interventions: BEHAVIORAL: Dialectical Behavior Therapy|BEHAVIORAL: Standard of Care Psychotherapy|OTHER: Pharmacotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fatty Acid Composition of Subcutaneous Adipose Tissue in Infants: A Prospective and Observational Study
Status: UNKNOWN
Conditions: Prematurity|Subcutaneous Adipose Tissue
Interventions: OTHER: adipose tissue|OTHER: blood|DIAGNOSTIC_TEST: PEAPOD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Soliqua 100/33 on Time in Range From Continuous Glucose Monitoring in Insulin-naive Patients With Very Uncontrolled Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine/Lixisenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stellate Ganglion Block in Obstructive Sleep Apnea
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: routine rehabilitation treatment|DEVICE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of E7389 in Patients With Breast Cancer, Previously Treated With Anthracycline, Taxane and Capecitabine
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: E7389
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dutogliptin|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiretroviral Therapy Intensification With Raltegravir or Addition of Hyper-immune Bovine Colostrum in HIV-1 Infected Patients With Suboptimal CD4+ T Cell Response
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Hyper-immune Bovine Colostrum|OTHER: raltegravir placebo|OTHER: Hyper-immune Bovine Colostrum placebo|DRUG: raltegravir and hyper-immune bovine colostrum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 7 Days of Grape Seed Extract Supplementation on Cold Pressor Test and Muscle Metaboreflex in Individuals With Elevated and Stage 1 Hypertension
Status: COMPLETED
Conditions: Prehypertension
Interventions: DIETARY_SUPPLEMENT: Grape Seed Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Macitentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Viral Shedding in Children Previously in Receipt of Multiple Doses of Live Attenuated Influenza Vaccine (LAIV) Compared to Influenza Vaccine-naïve Controls
Status: COMPLETED
Conditions: Influenza Vaccination|Influenza|Vaccination
Interventions: BIOLOGICAL: Fluenz Tetra (The two groups are defined by immunisation history, all receive the same intervention in the study)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glibenclamide (Dose to be Titrated From Starting Dose of 5mg om) Plus Rosiglitazone 4mg om (Increased to 8mg om After 6 Months) and vs Glibenclamide (Dose to be Titrated With Starting Dose of 5mg om) Plus Placebo, Administered to Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: titration|DRUG: titration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Supporting Oral and Long-acting PrEP Decision Making Among Pregnant Women in Lilongwe, Malawi
Status: NOT_YET_RECRUITING
Conditions: HIV Prevention
Interventions: BEHAVIORAL: My Choice for HIV Prevention (MyChoice)|BEHAVIORAL: Standard of care (control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Project to Evaluate the Revolutionizing Prosthetics Modular Prosthetic Limb System for Upper Extremity Amputees
Status: UNKNOWN
Conditions: Prosthesis Use|Limb Loss
Interventions: DEVICE: Modular Prosthetic Limb
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Adjuvant Treatment With Exemestane Following Previous Treatment With Tamoxifen in Postmenopausal Women With Estrogen Sensitive Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapist Guided, Parent-led, Cognitive Behavioural Therapy (CBT) for Preadolescent Children With Obsessive Compulsive Disorder (OCD)
Status: COMPLETED
Conditions: OCD
Interventions: BEHAVIORAL: Therapist guided, parent-led CBT for preadolescent children with OCD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Avagacestat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lessening Incontinence by Learning Yoga
Status: COMPLETED
Conditions: Urinary Incontinence|Stress Urinary Incontinence|Urge Urinary Incontinence|Over Active Bladder
Interventions: OTHER: Yoga Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Intravenous (IV) Pamidronate for Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DRUG: pamidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dyslipidemia of Obesity Intervention in Teens
Status: COMPLETED
Conditions: Dyslipidemia|Obesity
Interventions: DRUG: Pitavastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Instrumental and Manipulative Techniques for the Suboccipital Region in Subjects With Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Chronic Mechanical Neck Pain
Interventions: OTHER: suboccipital inhibition|OTHER: INYBI|OTHER: INYBI + upper cervical manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erectile Dysfunction, Psychological Disorders, and Sexual Performance Among Men Seeking Medical Help for Fertility
Status: UNKNOWN
Conditions: Erectile Dysfunction|Sexual Dysfunction|Premature Ejaculation|Infertile Men|Fertile Men|Wife's Miscarriage
Interventions: OTHER: A questionnaire method was used.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Osteoarthritis|Post-traumatic Arthritis|Collagen Disorders|Avascular Necrosis|Traumatic Femoral Fractures|Nonunion of Femoral Fractures|Congenital Hip Dysplasia|Slipped Capital Femoral Epiphysis
Interventions: DEVICE: Summit Tapered Hip System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Magnesium Sulphate as an Adjuvant to Levobupivacaine in Erector Spinae Block for Acute Pain Management in Modified Radical Mastectomy
Status: UNKNOWN
Conditions: Acute Pain
Interventions: PROCEDURE: erector spinae block with bupivacaine|PROCEDURE: erector spinae block with bupivacaine and magnesium sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DIETARY_SUPPLEMENT: selenomethionine|DRUG: carboplatin|DRUG: paclitaxel|OTHER: laboratory biomarker analysis|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and LBH589 in Hepatocellular Carcinoma (HCC)
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib + LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Continuous Apomorphine Infusion on Cognitive and Neuropsychological Functions in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinsons's Disease
Interventions: DRUG: Continuous Apomorphine infusion|DRUG: Usual dopaminergic per os treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Support Surfaces on the Properties Skin After Loading
Status: COMPLETED
Conditions: Pressure Ulcers
Interventions: OTHER: Alternating low pressure mattress with air loss function|OTHER: Gel mattress|OTHER: Basic foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of NRT6003 in Patients With Unresectable Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Unresectable Hepatocellular Carcinoma
Interventions: DRUG: NRT6003 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Remodeling in Subjective Memory Complaint (SMC): Brain Imaging and Blood Biochemistry Study
Status: COMPLETED
Conditions: Subjective Memory Complaint
Interventions: BEHAVIORAL: Lifestyle remodeling Intervention|BEHAVIORAL: Does Comparator: regular treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Involvement in CBGT of OCD: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: FB-CBGT|BEHAVIORAL: CBGT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain
Status: NOT_YET_RECRUITING
Conditions: Pain Cancer
Interventions: DEVICE: Ultrasound-guided percutaneous neuromodulation (NMP)|DRUG: pharmacological treatment by Opioids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Patients With Relapsed or Refractory EBV-and CD30-positive Lymphomas
Status: COMPLETED
Conditions: Relapsed or Refractory EBV-and CD30-positive Lymphomas
Interventions: DRUG: brentuximab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avastin+ GemAOD As First-Line Treatment in NK/T Cell Lymphoma
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma, Nasal Type
Interventions: BIOLOGICAL: Avastin|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Pegaspargase|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability of Betamethasone Oral Solution Metered Spray (GTX-102) in Healthy Subjects
Status: UNKNOWN
Conditions: Ataxia Telangiectasia
Interventions: DRUG: GTX-102 medium dose fast Period 1 and Period 2|DRUG: GTX-102 medium dose slow Period 1 and Period 2|DRUG: GTX-102 high dose fast Period 1 and Period 2|DRUG: GTX-102 low dose fast Period 1 and Period 2|DRUG: Betamethasone solution as intramuscular injection Period 1 and Period 2|DRUG: Betamethasone Oral Solution Period 1 and Period 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: NEO Rehab for Infants at Risk of Cerebral Palsy
Status: COMPLETED
Conditions: Prematurity|Cerebral Palsy
Interventions: OTHER: NICU-based rehabilitation bundle|OTHER: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Effect of Mirtazapine on Anxiety in Parkinson's Disease Patients
Status: RECRUITING
Conditions: Parkinson Disease|Anxiety
Interventions: DRUG: Mirtazapine 15 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Far Cortical Locking More Effective Than Bicortical Locking in Treating AO 43A1-3 Fractures?
Status: COMPLETED
Conditions: Tibia Distal Fracture|Nonunion of Fracture of Tibia
Interventions: PROCEDURE: Far Cortical Locking Technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ZR2 Followed by Immunochemotherapy in Elderly Patients With Newly-diagnosed DLBCL
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Rituximab, Lenalidomide, Zanubrutinib and RCHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physical Fatigue on Different Balance Tests and Brain Activity in a Healthy Population
Status: COMPLETED
Conditions: Physical Fatigue|Return to Sport|Injury Prevention|EEG|Brain Activity|Balance
Interventions: BEHAVIORAL: Physical Fatigue|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)
Status: RECRUITING
Conditions: Hyperoxia|Hypoxia
Interventions: DEVICE: Addition of ORi monitoring to SpO2 monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dalpiciclib Isethionate Tablets Combined With Abiraterone Acetate Tablets (I) and Prednisone Tablets (AA-P) Versus Placebo Combined With AA-P in Treatment of High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)
Status: NOT_YET_RECRUITING
Conditions: High-volume, Metastatic, Hormone-sensitive Prostate Cancer (mHSPC)
Interventions: DRUG: dalpiciclib isethionate tablets; abiraterone acetate tablets; prednisone tablets|DRUG: placebo; abiraterone acetate tablets; prednisone tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CM310 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CM310|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor and Clopidogrel on Reperfusion in Patients With AMI
Status: UNKNOWN
Conditions: Myocardial Infarction|No-Reflow Phenomenon
Interventions: DRUG: Ticagrelor|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT