pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multifaceted Telemedicine-Based Intervention to Improve Outcomes of Cancer Patients Admitted to the ICU
Status: NOT_YET_RECRUITING
Conditions: Active Malignancies|Life Threatening Complication of the Malignancy or Its Treatments
Interventions: OTHER: Telemedicine-based intervention|OTHER: Standard of care arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MaaT013 as Salvage Therapy in Ruxolitinib Refractory GI-aGVHD Patients
Status: RECRUITING
Conditions: Acute Graft Versus Host Disease in Intestine|Steroid Refractory GVHD
Interventions: DRUG: MaaT013
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of 5LGr to Treat Tic Disorder
Status: COMPLETED
Conditions: Tic Disorder|Tourette Syndrome|Chronic Tic Disorder
Interventions: DRUG: 5LGr|DRUG: tiapride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF
Status: UNKNOWN
Conditions: Coronary Artery Disease|Anemia
Interventions: PROCEDURE: Centrifugation Method|PROCEDURE: Online MUF|PROCEDURE: Offline MUF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Rapamycin - Effects on Alzheimer's and Cognitive Health
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: Rapamycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Complement Inhibition in Early, Newly Developing Septic Organ Dysfunction
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock
Interventions: BIOLOGICAL: CaCP29|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tramadol and Tramadol Plus Ketamine for Shivering Prevention After Spinal Anesthesia in Lower Segment Caeserian Section
Status: RECRUITING
Conditions: Shivering
Interventions: DRUG: Tramadol with Ketamine|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Acceptability, Gastro Intestinal Tolerance Compliance of a Paediatric Tube-feed Formula Derived From Food for Children
Status: COMPLETED
Conditions: Child Nutrition Disorders
Interventions: OTHER: Pediatric Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Monoclonal Antibody Plus Chemotherapy in Treating Patients With Advanced Colorectal Cancer That Overexpresses HER2
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Intraoperative Hemoperfusion on Acute Kidney Injury After Aortic Dissection
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection
Interventions: DEVICE: Intraoperative Hemoperfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Irinotecan and Temozolomide in Children With Brain Tumors.
Status: COMPLETED
Conditions: Glioma|Medulloblastoma
Interventions: DRUG: Irinotecan|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterisation of Cortical Vestibular Evoked Potentials (C-VEPs)
Status: UNKNOWN
Conditions: Vestibular Neuronitis
Interventions: PROCEDURE: cortical vestibular evoked potentials (CVEPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of High Intensity Interval Training in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: high intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Surgical Treatment for Morbid Obesity by Sleeve Gastrectomy Versus Gastric Bypass
Status: COMPLETED
Conditions: Obesity
Interventions: PROCEDURE: Sleeve gastrectomy|PROCEDURE: Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to Rotavirus Vaccine After a Supplemental Dose Given at 9 Months of Age With Local EPI Vaccines in Mali
Status: COMPLETED
Conditions: Diarrhea Rotavirus
Interventions: BIOLOGICAL: pentavalent rotavirus vaccine (PRV)|BIOLOGICAL: measles vaccine (MV)|BIOLOGICAL: yellow fever vaccine (YFV)|BIOLOGICAL: meningitis conjugate vaccine (PsA-TT-5μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability and Efficacy of Incremental Doses of MGB-BP-3 in Patients With CDAD
Status: COMPLETED
Conditions: Clostridium Difficile Infection
Interventions: DRUG: MGB-BP-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Functional Electric Stimulation for Recovery of Dorsiflexion After Stroke
Status: RECRUITING
Conditions: Stroke|Ambulation Difficulty|Hemiplegia
Interventions: DEVICE: FES and Conventional training|DEVICE: AFO and Conventional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cortical Electrophysiology of Response Inhibition in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Levodopa|DEVICE: Clinical DBS Setting|DEVICE: Sham DBS|DEVICE: DBS Setting Maximizing Prefrontal Activation|DEVICE: DBS Setting Minimizing Prefrontal Activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ramelteon vs Placebo for Prevention of Delirium and Improvement of Sleep in Hospitalized Older Adults
Status: WITHDRAWN
Conditions: Delirium in Old Age
Interventions: DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Spironolactone on Matrix Metalloproteinases (MMPs) in Heart Failure
Status: COMPLETED
Conditions: Chronic Stable Heart Failure
Interventions: DRUG: spironolactone + furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PH I SRC Kinase, Dasatinib Combo Paclitaxel & Carboplatin in Pts w Ovarian, Peritoneal, & Tubal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: DRUG: Dasatinib, Paclitaxel, and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Revised Capsular Polishing and Its Impact on the Positioning of the Intraocular Lens and Visual Quality Following Femtosecond Laser-assisted Cataract Surgery
Status: RECRUITING
Conditions: Cataract
Interventions: PROCEDURE: improved capsular polishing|PROCEDURE: the conventional I/A polishing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate An NK-1 Antiemetic For The Prevention Of Post Operative Nausea And Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Nausea and Vomiting, Postoperative
Interventions: DRUG: intravenous ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa|Osteopenia|Osteoporosis|Eating Disorders
Interventions: DRUG: Recombinant Human Growth Hormone|DRUG: Placebo for Recombinant Human Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Music Activity INTervention for Adherence Improvement Through Neurological Entrainment
Status: COMPLETED
Conditions: Myocardial Infarction|Compliance Behavior|Patient Compliance
Interventions: BEHAVIORAL: Preference Based Rhythmic Auditory Stimulation Music|OTHER: Preference Based Music Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies
Status: COMPLETED
Conditions: Solid Tumor Malignancies
Interventions: DRUG: Imetelstat Sodium (GRN163L)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Functional Exercises on Balance With Postural Thoracic Kyphosis
Status: COMPLETED
Conditions: Postural Kyphosis|Balance
Interventions: BEHAVIORAL: The Group I Postural Exercise|BEHAVIORAL: The Group II Three-dimensional Exercise Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Status: RECRUITING
Conditions: Solid Tumor, Adult|Colorectal Cancer|NSCLC|Non Small Cell Lung Cancer|NSCLC, Recurrent|Non-Small Cell Squamous Lung Cancer|Pancreas Cancer|Pancreatic Neoplasm|Colorectal Adenocarcinoma|CRC|Colon Cancer|Rectal Cancer|Cancer|Ovarian Cancer|Ovarian Neoplasms|Mesothelioma|Mesothelioma, Malignant|Ovary Cancer|Lung Cancer|MESOM
Interventions: BIOLOGICAL: A2B694|DIAGNOSTIC_TEST: xT CDx with HLA-LOH Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DZD8586 in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (TAI-SHAN9)
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: DZD8586|DRUG: DZD8586|DRUG: DZD8586
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Screw Fixation Versus Halo Immobilization of Type II Odontoid Fractures in Geriatric Patients With Increased Anesthesia Risk
Status: COMPLETED
Conditions: Spinal Fractures
Interventions: OTHER: ANTERIOR SCREW FIXATION|OTHER: HALOV VEST IMMOBILIZATION
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Intervention After Cancer Treatment for Improving Health in Stage II-III Breast Cancer Survivors
Status: COMPLETED
Conditions: Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Cancer Survivor|Estrogen Receptor Positive|HER2/Neu Negative|Progesterone Receptor Positive|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Sedentary Lifestyle
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Informational Intervention|OTHER: Laboratory Biomarker Analysis|DEVICE: Monitoring Device|OTHER: Questionnaire Administration|OTHER: Physical Performance Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessing the Clinical Benefits of a Pharmacogenetics-Guided Dosing Regiment for Calculating Warfarin Maintenance Dose
Status: UNKNOWN
Conditions: Indications for Warfarin Therapy
Interventions: DRUG: Warfarin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pretreatment With Roc on Succinylcholine Myalgias
Status: COMPLETED
Conditions: Myalgia
Interventions: OTHER: non-pretreated Succinylcholine|DRUG: succinylcholine 1 minute after rocuronium pretreatment|DRUG: succinylcholine 2 minutes following rocuronium pretreatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bedside Versus Operating Room Burr-Hole Drainage of Chronic Subdural Hematoma (DECIDE)
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: PROCEDURE: CSDH - Bedside twist drill technique|PROCEDURE: CSDH - Operating Room Burr-hole technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Disease-Modifying Antirheumatic Drugs (DMARDs) Versus Sulfasalazine in Inflammatory Back Pain
Status: COMPLETED
Conditions: Seronegative Spondyloarthropathies
Interventions: DRUG: Methotrexate, Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About the Study Medicine (PF-07293893) at Different Dose Levels in Healthy Adults
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-07293893|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Renal Denervation in Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Persistent Proteinuria With Type II Diabetes
Interventions: PROCEDURE: Percutaneous renal denervation and TMNS|DRUG: Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
Status: COMPLETED
Conditions: Environmental Enteric Dysfunction|Zinc Deficiency|Vitamin A Deficiency
Interventions: DRUG: 3 mg zinc sulfate supplement|DRUG: 0.5 mg of 13C10-retinyl-acetate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI and Rescue-PCI
Status: COMPLETED
Conditions: Myocardial Infarction|Ischemia
Interventions: DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Irrisept to Saline Irrigation for Infection Prevention
Status: TERMINATED
Conditions: Gustilo-Anderson Type III Open Tibia Fracture
Interventions: DRUG: Irrisept (Irrigation Solution)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigational Vaccine for the Prevention of Disseminated Tuberculosis in HIV Infected People
Status: COMPLETED
Conditions: Tuberculosis|HIV Infections
Interventions: BIOLOGICAL: SRL-172
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of N-Acetylcysteine in Prevention of Post-Catheterization Contrast-Induced Nephropathy in Diabetic Patients With Chronic Kidney Disease
Status: COMPLETED
Conditions: Radiocontrast-Induced Nephropathy|Chronic Kidney Disease|Diabetes Mellitus
Interventions: DRUG: N-acetylcysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine Besylate / Benazepril Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison for Pethidine Requirement in Patients Received Spinal Morphine 0.2 and 0.3 mg for Post Lobectomy Analgesia
Status: COMPLETED
Conditions: Solitary Mass|Lung Diseases
Interventions: DRUG: spinal morphine 0.3 mg|DRUG: spinal morphine 0.2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Antalgic Effect of Pulse Frequency and Pad Size of TENS on Blunt Pressure Pain
Status: COMPLETED
Conditions: Transcutaneous Electrical Nerve Stimulation|Blunt Pressure Pain|Pad Size|Pulse Frequency|Analgesia
Interventions: DEVICE: Control TENS|DEVICE: Sham TENS|DEVICE: High frequency TENS with large pads|DEVICE: Low frequency TENS with large pads|DEVICE: High frequency TENS with small pads|DEVICE: Low frequency TENS with small pads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Stenosis
Interventions: DEVICE: Coronary stent implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Photoxicity and Photoallergy Study of a Developmental Face Cream, Serum and Lotion
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Serum|OTHER: Lotion|OTHER: Cream|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Exploring the Value of 18F-AlF-FAPI PET/CT in Assessing the Activity of Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DIAGNOSTIC_TEST: 18F-AlF-FAPI PET/CT, 99mTc-DTPA SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Obesity on Clinical Outcomes in Patients Receiving Acyclovir for HSV Encephalitis"
Status: COMPLETED
Conditions: HSV Encephalitis
Interventions: OTHER: To assess the clinical impact of dosing acyclovir based on IBW or adjBW for HSV encephalitis to definitively guide safe and effective therapy.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Frontotemporal Dementia
Interventions: DRUG: AL001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corifollitropin Alfa Versus Recombinant Follicle Stimulating Hormone (FSH) in Ovarian Stimulation of Women Undergoing in Vitro Fertilisation
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: corifollitropin alfa|DRUG: recombinant follicle stimulating hormone (FSH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Darbepoetin in Low-Intermediate Risk Myelodysplastic Syndrome (MDS)
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study in Removing Excess Iron From the Heart
Status: COMPLETED
Conditions: Thalassemia Major|Hemosiderosis
Interventions: DRUG: Ferriprox (deferiprone)|DRUG: Desferal (deferoxamine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telling Our Daughters Our Story
Status: ACTIVE_NOT_RECRUITING
Conditions: Substance Use|Sexual Behavior
Interventions: BEHAVIORAL: Nowhi Isdza bit Nadagoldi: Telling Our Daughters Our Story (TODOS)|BEHAVIORAL: Control condition - 3 Monthly Group Activities in the Community
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study to Evaluate the Efficacy, Safety and Tolerability of AZD5069 in Patients With Uncontrolled Persistent Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD5069|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib Plus Gemcitabine in Pancreatic Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Pancreatic Cancer
Interventions: DRUG: Masitinib|DRUG: Gemcitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Fibrin in Brains With AD/ADRD
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia of Alzheimer Type
Interventions: DIAGNOSTIC_TEST: PET/MR Imaging|DRUG: 64Cu-FBP8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Avo In R/R And Previously Untreated MCL
Status: RECRUITING
Conditions: Mantle Cell Lymphoma|Refractory Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Venetoclax|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rubber Band Ligation and Haemorrhoidectomy in Patients With Symptomatic Haemorrhoids Grade III
Status: UNKNOWN
Conditions: Hemorrhoids|Hemorrhoids, Internal|PROM|Rectal Diseases
Interventions: PROCEDURE: RBL|PROCEDURE: Hemorrhoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Plus Gemcitabine (EG) vs Paclitaxel Plus Gemcitabine (PG) in HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Eribulin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Studying Safety & Efficacy of Axiostat® Dressing in Acute Hemorrhage Due to Trauma-Comparative Study
Status: COMPLETED
Conditions: Bleeding
Interventions: DEVICE: Axiostat®|DEVICE: Cotton Gauze
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Vaccination in Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Inflammatory Bowel Disease|Crohn Disease|Ulcerative Colitis
Interventions: BIOLOGICAL: 23-valent polysaccharide pneumococcal vaccine (Pneumovax TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study for Patients With Diabetes Mellitus (IOPA)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Human insulin 30/70|DRUG: Insulin lispro low mix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating DVS-233 for Treatment of Outpatients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: DVS-233 SR (desvenlafaxine sustained release )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genital CT Treatment to Pregnant Women to Prevent Adverse Pregnancy Outcomes: A Pilot RCT
Status: COMPLETED
Conditions: Chlamydia Trachomatis Infection
Interventions: DIAGNOSTIC_TEST: C. trachomatis and N. gonorrhoeae|DRUG: Azithromycin|OTHER: Partner notification and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases
Interventions: DRUG: Oxaliplatin|DRUG: Fluorouracil|DRUG: Serplulimab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibrous Dysplasia Of Bone
Interventions: DRUG: Burosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training Intensity and Nitrate Supplementation in Post-Menopausal Females
Status: NOT_YET_RECRUITING
Conditions: Menopause
Interventions: DIETARY_SUPPLEMENT: Berkeley Life Pro Nitrate Capsules|BEHAVIORAL: High Intensity Exercise|BEHAVIORAL: Moderate Intensity Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Whey Protein-based Enteral Nutrition Support to Improve Protein Economy in Surgical Patients
Status: COMPLETED
Conditions: Protein Metabolism|Colorectal Neoplasms
Interventions: DIETARY_SUPPLEMENT: Oral Nutrition Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin's Lymphoma|Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of All-on-4 PEEK and Conventional Prostheses
Status: ENROLLING_BY_INVITATION
Conditions: Failure, Prosthesis|Dental Prosthesis, Implant-Supported|Survival, Prosthesis|Complete Edentulism|Complication;Prostheses
Interventions: PROCEDURE: Accuracy of full-arch surgical guides|PROCEDURE: Survival and complications of the prostheses|PROCEDURE: Survival and complications of the implants|PROCEDURE: Conventional (metal-resin) implant-supported prosthesis|PROCEDURE: PEEK implant-supported prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COVID-2019 Testing and Vaccination Among African American and Latinx Public Housing Residents
Status: WITHDRAWN
Conditions: Coronavirus
Interventions: BEHAVIORAL: Increasing Willingness and Uptake of COVID-19 Testing and Vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemp Seed Protein and Bioactive Peptides Consumption for Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Whole hemp seed protein|OTHER: Whole hemp seed protein plus bioactive peptides|OTHER: Casein protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Aiming to Evaluate the Efficacy and Safety of Nilotinib Patients With Gastrointestinal Stromal Tumors (GIST) Resistant or Intolerant to Imatinib and or to 2nd Line Tyrosine Kinas (TK) Inhibitor
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors (GIST)
Interventions: DRUG: AMN107- NILOTINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution and Treatments of Chronic Inflammatory Systemic Diseases
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease|Arthritis, Rheumatoid|Spondyloarthritis|Psoriatic Arthritis|Psoriasis|Verneuil's Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effortful Swallow Maneuver for Swallowing Impairment in People With Parkinson Disease
Status: COMPLETED
Conditions: Parkinson Disease|Dysphagia
Interventions: BEHAVIORAL: Effortful Swallow Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation Assisted Fiber-optic Bronchoscopy
Status: RECRUITING
Conditions: Lung|Diseases
Interventions: DEVICE: non- invasive ventilator|DEVICE: fiber-optic bronchoscopy|DEVICE: non- invasive ventilator|DEVICE: fiber-optic bronchoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Oral Steroid in Controlling Pain After TKA
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: DRUG: Dexamethasone Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smart Phone Medication Adherence Saves Kidneys--SMASK
Status: COMPLETED
Conditions: Kidney Transplantation|Medication Adherence|Hypertension
Interventions: BEHAVIORAL: SMASK|BEHAVIORAL: EnhancedSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Tolerance and Biological Activity of Oral Clioquinol in Patients With Relapsed or Refractory Hematological Malignancy
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Myelodysplasia|Lymphoma, Non-Hodgkin|Hodgkin's Lymphoma|Multiple Myeloma
Interventions: DRUG: Clioquinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Safety and Efficacy of Perrigo's Drug Compared to an FDA Approved Drug in the Treatment of Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol Mebutate (Perrigo)|DRUG: Ingenol Mebutate (Reference)|DRUG: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Zolmitriptan (Zomig) in the Treatment of Migraines in Adolescents
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Zolmitriptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Multi-center, Open-label, Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: isatuximab SAR650984 IV|DRUG: pomalidomide|DRUG: dexamethasone|DRUG: isatuximab SAR650984 SC|DEVICE: Investigational injector device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IDH2-Post-Allo-Trial for Patients With IDH2-mut Myeloid Neoplasms After Allo-SCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Myeloid, Acute|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|IDH2 Gene Mutation|IDH2 R172|IDH2 R140
Interventions: DRUG: Enasidenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Sex Hormones Variation During Third Trimester of Pregnancy and Post-partum on QT Interval Duration
Status: COMPLETED
Conditions: Pregnancy
Interventions: OTHER: evaluation of QT interval duration|OTHER: circulating sex hormones levels sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Trial of Inhaled Anti-viral (SNG001) for SARS-CoV-2 (COVID-19) Infection
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: DRUG: SNG001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3549492 in Participants With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY3549492|DRUG: Placebo|DRUG: Atorvastatin|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma.
Status: RECRUITING
Conditions: Glaucoma
Interventions: DEVICE: MINIject™ Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Heated vs. Pulsed Radiofrequency Treatment of the Genicular Nerves for Osteoarthritis Knee Pain
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction
Status: COMPLETED
Conditions: Biliary Calculi
Interventions: DEVICE: Balloon catheter|DEVICE: Basket catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety, Tolerability, PK and PD of ELX-02 in Cystic Fibrosis Patients With G542X Allele
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX-02|DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wide Excision of Soft Tissue Sarcomas in Combination With Interstitial Radiation Therapy
Status: RECRUITING
Conditions: Sarcoma|Soft Tissue Sarcoma
Interventions: RADIATION: Interstitial radiation therapy|RADIATION: Postoperative external beam therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane (ESP) Versus Paravertebral Nerve (PVB) Blockade for Acute Unilateral Rib Fracture Pain
Status: TERMINATED
Conditions: Rib Fractures|Pain, Acute|Thoracic Injuries|Neuropathic Pain|Neuromuscular Blockade|Anesthesia, Local
Interventions: DRUG: Erector Spinae Plane Block|DRUG: Paravertebral Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaginal CO2 Laser in Postmenopausal Women With Overactive Bladder Syndrome (OAB)
Status: COMPLETED
Conditions: Overactive Bladder (OAB)
Interventions: DEVICE: Microablative Fractional CO2 laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pregnancy and Postpartum Period Venous Thromboembolism and Simulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Simulation|Venous Thromboembolism
Interventions: OTHER: Simulation application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dose Finding Study of Vedolizumab for GvHD in Participants Undergoing Allogeneic HSCT
Status: COMPLETED
Conditions: Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simultaneously Targeting Obesity and Pain: The STOP Trial
Status: UNKNOWN
Conditions: Obesity|Chronic Pain
Interventions: BEHAVIORAL: Intervention Simultaneously Targeting Obesity and Pain|BEHAVIORAL: Weight Loss/Weight Self-Management|BEHAVIORAL: Chronic Pain Self-Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment Vitamin D Analogues Intake Pathways on the Proteins Which Involved in Metabolic Rate in Obese Subjects
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Vitamin D analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Oral Cannabis Administration and Co-Administration of Alcohol on Impairment
Status: RECRUITING
Conditions: Cannabis Intoxication|Alcohol Intoxication
Interventions: DRUG: Cannabis|DRUG: Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Status: WITHDRAWN
Conditions: Carcinoma, Squamous|Squamous Cell Carcinoma|Oropharyngeal Neoplasms|Oropharyngeal Cancer
Interventions: DRUG: cisplatin|DRUG: Cetuximab|DRUG: BYL719
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Refractory Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: masitinib 3 mg|DRUG: masitinib 6.0 mg|DRUG: methotrexate|DRUG: Placebo (methotrexate)|DRUG: Placebo (masitinib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 64 Cu-DOTA-alendronate PET Imaging in Localizing and Characterizing Breast Calcifications in Participants Before Undergoing Mastectomy
Status: COMPLETED
Conditions: Breast Carcinoma|Calcification
Interventions: PROCEDURE: Computed Tomography|DRUG: Copper Cu-64-DOTA-alendronate|OTHER: Pharmacokinetic Study|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The ACTIVE Trial: A Prospective Randomised Control Trial Of The H1 Implant Versus Total Hip Replacement
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Hip|Inflammatory Arthritis
Interventions: DEVICE: The H1 Implant|DEVICE: Cementless total hip replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Weekly Paclitaxel With Oncothermia and Weekly cisPlatin With Oncothermia in Patients With Recurrent or Persistent Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Carcinoma|Fallopian Tube Carcinoma|Primary Peritoneal Carcinoma
Interventions: DRUG: weekly paclitaxel|DRUG: weekly cisplatin|DEVICE: oncothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transverse Abdominis Plane Block Guided by Ultrasound on the Postoperative Analgesia and Quality of Lives Among the Patients Undergo Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Post-operative Pain|Inguinal Hernia
Interventions: PROCEDURE: TAPB group|PROCEDURE: PCIA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COmbination of Radiotherapy With Anti-PD-1 Antibody for unREseCtable Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer|Radiotherapy|Immunotherapy
Interventions: COMBINATION_PRODUCT: Radiotherapy+anti-PD-1 antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neostigmine and Glycopyrrolate by Iontophoresis
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Constipation|Fecal Incontinence|Neurogenic Bowel
Interventions: DRUG: Combination of Neostigmine and Glycopyrrolate|DEVICE: I-Box by Dynatronics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AZD2014 and Weekly Paclitaxel in Squamous NSCLC
Status: TERMINATED
Conditions: Squamous Non Small Cell Lung Cancer
Interventions: DRUG: Open-label AZD2014|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selfcare MAnagement InteRvenTion in COPD (SMART COPD)
Status: COMPLETED
Conditions: Copd|Assessment, Self|Hospitalization
Interventions: DEVICE: LifePod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility of Carbon-Dye Marking of Axillary Lymph Nodes Before Neoadjuvant Chemotherapy in Patients With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Carbon Black Tattoo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of GH21 Combined With Previous Target Therapy or Immunotherapy in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Patients With Advanced Solid Tumor|Advanced Solid Tumor With Oncogenic Driver Mutations
Interventions: DRUG: PD-1|DRUG: MET inhibitor|DRUG: ALK inhibitor|DRUG: BRAF Inhibito|DRUG: EGFR Monoclonal antibody|DRUG: GH21|DRUG: MEK Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PelvEx - Beating the Empty Pelvis Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Empty Pelvis Syndrome|Pelvic Exenteration|Pelvic Neoplasm|Pelvic Cancer|Rectal Cancer|Postoperative Complications
Interventions: OTHER: Consensus study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intra-articular Dexmedetomidine Versus Neostigmine After Knee Arthroscopy (a Comparative Study)
Status: COMPLETED
Conditions: Knee Injuries
Interventions: DRUG: dexamedetomidine|DRUG: neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of YM060 in Female Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS)
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome
Interventions: DRUG: YM060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of B-cell Depletion by Rituximab and Anti-CD 19 CAR-T Therapy in Patients With Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: KYV101|DRUG: Rituximab (active comparator)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of the Effect of Pressure-controlled Ventilation and Volume-controlled Ventilation on the Gastric Insufflations in I-gel
Status: COMPLETED
Conditions: General Anesthesia
Interventions: OTHER: Volume-controlled ventilation|OTHER: Pressure-controlled ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Weekly Intravenous Administration of OctaAlpha1 With a Marketed Preparation Glassia® in Subjects With Alpha-1-antitrypsin Deficiency
Status: WITHDRAWN
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: DRUG: OctaAlpha1|DRUG: Glassia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT