pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between the Analgesic Effectiveness of Virtual Reality and Topical Anesthesia: A Clinical Study
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Dental injection and topical gel application|DEVICE: Dental injection and virtual reality device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Piezosurgey Corticotomy (a Minimally Invasive Surgical Technique) in Accelerating Orthodontic Alignment
Status: COMPLETED
Conditions: Surgical Incision|Malocclusion
Interventions: PROCEDURE: Piezosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Economic Evaluation of Primovist-enhanced Liver MRI
Status: COMPLETED
Conditions: Colorectal Neoplasms|Neoplasm Metastasis
Interventions: PROCEDURE: Primovist MRI|PROCEDURE: Extracellular contrast media (ECCM) MRI|PROCEDURE: Contrast-enhanced CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immediate Effects of Kinesio Taping Applied to the Thoracic Region in Adult Individuals
Status: UNKNOWN
Conditions: Kinesio Taping|Healthy Adults
Interventions: OTHER: Kinesio taping|OTHER: Placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Lung Disease
Interventions: DRUG: AZD2423|DRUG: AZD2423 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Transcranial Magnetic Stimulation and Constraint Induced Movement Therapy in Pediatric Unilateral Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Sham Transcranial Magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Different Levels of Decreased Liver Function Influence Blood Levels of Elinzanetant Compared to Normal Liver Function in Male and Female Participants
Status: COMPLETED
Conditions: Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Interventions: DRUG: BAY3427080
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids
Status: UNKNOWN
Conditions: Adipose Derived Stem Cells|Keloid
Interventions: PROCEDURE: Autologous Adipose Derived stem cell transplantation|DRUG: Triamcinolone Acetonide 40Mg/Ml Inj,Susp_#1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on PET Imaging, Distribution and PK of 89Zr-CD147 in Patients With Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor
Interventions: DRUG: 89Zr-CD147
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: DRUG: Selinexor|DRUG: Venetoclax|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RiaSTAP vs. Conventional Transfusion in Patients Having Heart Valve Surgery
Status: TERMINATED
Conditions: Heart Valve Disease|Coronary Artery Disease
Interventions: DRUG: Human fibrinogen concentrate|OTHER: apheresis platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Dye Laser and Intense Pulsed Light (IPL) for the Treatment of Telangiectasia and Skin Redness
Status: UNKNOWN
Conditions: Telangiectasis|Erythema
Interventions: DEVICE: Pulsed dye laser|DEVICE: Intense pulsed light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: RE and Probiotics in MAFLD/NAFLD
Status: NOT_YET_RECRUITING
Conditions: NASH|NAFLD|MAFLD
Interventions: BEHAVIORAL: physical exercise programme|DIETARY_SUPPLEMENT: probiotics supplementation|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab With or Without Interferon Alfa in Treating Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Recombinant Interferon Alfa|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS in Managing Individuals With Chronic Low Back Pain and Comorbid Insomnia
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Insomnia
Interventions: DEVICE: M1 or DLPFC sham stimulation|DEVICE: M1 rTMS|DEVICE: DLPFC rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Coronary Artery Bypass Grafting|Mitral Valve Surgery|Low Cardiac Output Syndrome
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas
Status: COMPLETED
Conditions: Low-grade Glioma|Pediatric Brain Tumor
Interventions: DRUG: combined therapy with rh-ES and CV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Volatile Organic Compounds in Expired Air in Healthy Volunteers: Comparison of Three Mass Spectrometry Techniques for the Characterization of Volatolome in Clinical Studies
Status: RECRUITING
Conditions: Respiratory Disease
Interventions: OTHER: Three spectrometry differents technics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy
Status: COMPLETED
Conditions: Prevention of BMD Loss After THR|Serum Markers of Bone Turnover|Functional Outcomes
Interventions: DRUG: Aclasta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery
Status: UNKNOWN
Conditions: Congenital Heart Disease
Interventions: BIOLOGICAL: Platelet transfusion|BIOLOGICAL: Fibrinogen concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Superficial Parasternal Intercostal Plane Block on Pulmonary Function Tests After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Pulmonary Function Tests
Interventions: PROCEDURE: superficial parasternal intercostal plane block|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neuromuscular Blockade Reversal Agent Effect on Postoperative Cognitive Function and Behaviour in Children
Status: COMPLETED
Conditions: Anesthesia; Functional
Interventions: DRUG: neostigmine - atropine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Gonadotrophin Dosage Using a Threshold Nomogram for Ovulation Induction in WHO Group II Anovulatory Infertility
Status: COMPLETED
Conditions: Anovulation|Infertility
Interventions: DRUG: Menopur
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Prednisone as First-Line Therapy in Treating Patients With Immune Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Nonneoplastic Condition
Interventions: BIOLOGICAL: Rituximab|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Digital Technology Versus Conventional Relining Procedure for Correction of Loose Maxillary Complete Denture
Status: COMPLETED
Conditions: Dental Diseases|Dental Trauma|Bone Remodeling Disorder
Interventions: OTHER: relining technique|OTHER: CAD/CAM milling technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Direct Application of Systane Complete to Contact Lenses
Status: COMPLETED
Conditions: Dry Eye|Contact Lens Complication
Interventions: DRUG: Systane Complete|DRUG: Sensitive Eyes Rewetting Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of Cannabis on Cognition and Mobility in Older HIV-infected and HIV-Un-infected Women
Status: COMPLETED
Conditions: HIV|AIDS|Aging
Interventions: DRUG: Cannabis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Open Label Extension Study to Evaluate the Safety and Tolerability of Oral Fampridine-Sustained Release (SR) in Canadian Participants With Multiple Sclerosis Who Participated in Acorda Extension Trials.
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: BIIB041 (Fampridine-SR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Current Neuromuscular Electrical Stimulation for Treatment of Peripheral Neuropathy
Status: COMPLETED
Conditions: Neuropathy
Interventions: DEVICE: Neubie Direct Current Electrical Stimulation Device|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium-Potassium Blood Pressure Trial in Children
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Vascular Diseases
Interventions: BEHAVIORAL: diet, sodium-restricted|BEHAVIORAL: diet, potassium-supplemented
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Voxelotor for Sickle Cell Anemia Patients at Highest Risk for Progression of Chronic Kidney Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Nephropathy
Interventions: DRUG: Voxelotor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of VNX001 Compared to Its Individual Components (Lidocaine and Heparin) or Placebo in Subjects With IC/BPS
Status: RECRUITING
Conditions: Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DRUG: VNX001|DRUG: Placebo|DRUG: Lidocaine|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK Biologicals' candidate Plasmodium falciparum malaria vaccine 257049
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Identification of the Most Suitable Questionnaire to Assess the Sexual Function of Women Living in France After Colorectal Cancer Surgery
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: OTHER: administration of the 4 quality of sexual life questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Value of Prothrombin Fragment F1+2 in the Diagnosis of Pulmonary Embolism in Patients With Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Embolism
Interventions: OTHER: CT pulmonary angio, blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Beta Blockers and Angiotensin Receptor Blockers in Bicuspid Aortic Valve Disease Aortopathy (BAV Study)
Status: TERMINATED
Conditions: Cardiac Disease
Interventions: DRUG: Atenolol|DRUG: Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Pharmacist Recommendations on Quality of Care in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Pharmacist recommendations to primary care providers|OTHER: pharmacist recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Providing Accessible Diagnostic Evaluations and Psychoeducation for Autism Spectrum Disorder in Rural Southwest Virginia
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: In-person Psychoeducation (IP)|BEHAVIORAL: Telehealth Psychoeducation (TH)|BEHAVIORAL: Psychoeducation as Usual (PAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Chronic Intranasal Oxytocin Administration on Sexual Function in Pre- and Postmenopausal Women
Status: COMPLETED
Conditions: Female Sexual Dysfunction
Interventions: DRUG: Syntocinon Nasalspray|DRUG: Placebo Nasalspray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CRAFT: The NCT-PMO-1602 Phase II Trial
Status: RECRUITING
Conditions: Metastatic or Locally Advanced Malignancies
Interventions: DRUG: Vemurafenib|DRUG: Cobimetinib|DRUG: Atezolizumab|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Alectinib|DRUG: Ipatasertib|DRUG: Atezolizumab|DRUG: Atezolizumab|DRUG: Atezolizumab|DRUG: Inavolisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A When Administered Subcutaneously Intramuscularly in Adults Aged ≥50 Years
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: Herpes zoster vaccine GSK1437173A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Patient Experience With a Surgically-assisted Acceleration Method of Orthodontic Treatment
Status: COMPLETED
Conditions: Crowding, Tooth
Interventions: PROCEDURE: Corticision|DEVICE: Conventional fixed appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CX717 in the Treatment of Adult ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: CX717 200 mg|DRUG: CX717 800 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINE
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Immunonutrition and Cardiac Patients
Status: COMPLETED
Conditions: Cardiac Function
Interventions: DIETARY_SUPPLEMENT: IV Immunonutrition|DIETARY_SUPPLEMENT: Conventional Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Hypertension, Pulmonary
Interventions: DRUG: MK-5475|DRUG: Placebo to MK-5475
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Aedes-borne Diseases|Dengue|Chikungunya|Zika
Interventions: BIOLOGICAL: Targeted Indoor Residual Spraying (TIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transarterial Chemoembolization vs CyberKnife for Recurrent Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: CyberKnife|PROCEDURE: TACE|DRUG: CT Contrast|DRUG: doxorubicin|DRUG: Epirubicin|DRUG: 5-fluorouracil|DRUG: Mitomycin C|DRUG: Gemcitabine|DRUG: Cisplatin|DEVICE: SMANCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ATORvastatin in Pulmonary TUBerculosis
Status: RECRUITING
Conditions: Pulmonary Tuberculosis|Tuberculosis|Koch's Disease
Interventions: DRUG: Atorvastatin 20mg|DRUG: Atorvastatin 40mg|DRUG: Atorvastatin 60mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DLBS1033 for Acute Ischemic Stroke Patients
Status: TERMINATED
Conditions: Acute Ischemic Stroke|Partial Anterior Circulation Infarct|Lacunar Anterior Circulation Infarct
Interventions: DRUG: DLBS1033|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Importance of the Gut Microbiota in Body Weight Control and Insulin Sensitivity
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DRUG: Amoxicillin|DRUG: Vancomycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Clinical Trial of Vitamin D3 for Reducing Recurrence of Recurrent Lower Urinary Tract Infections
Status: RECRUITING
Conditions: Recurrent Urinary Tract Infection
Interventions: DRUG: Vitamin D3 4000 IU|DRUG: Vitamin D3 2000 IU|DRUG: Placebo|OTHER: standard antibiotic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorinostat, Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Upper Gastrointestinal Cancer
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer|Liver Cancer
Interventions: DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: vorinostat|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ergonomics in Ultrasound Procedures
Status: NOT_YET_RECRUITING
Conditions: Procedural Complication|Competence
Interventions: OTHER: Frontal Ultrasound Machine|OTHER: Lateral Ultrasound Machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Two Treatments on Nonspecific Neck Pain
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Ischemic compression|OTHER: Instrument assisted soft tissue mobilization Group|OTHER: Exercise and workplace modifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Knee-extensor Exercise Training in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: High intensity knee-extensor training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 24-months Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor
Status: RECRUITING
Conditions: Parkinson Disease|Essential Tremor
Interventions: DEVICE: Peroneal electrical transcutaneous neuromodulation (peroneal eTNM®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Valid Test Battery for Assessing Driving Ability When Influenced by Drugs.
Status: COMPLETED
Conditions: Automobile Driving
Interventions: DRUG: ethanol|DRUG: Ethanol|OTHER: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: RFA vs. SBRT for Small HCC
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: stereotactic body radiotherapy (SBRT)|PROCEDURE: Radiofrequency ablation (RFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Two Different Chinese Traditional Medicine Treatment on Chronic Hepatitis B
Status: UNKNOWN
Conditions: Hepatitis B， Chronic
Interventions: DRUG: Standard - Yinchengao Decoction plus Ganlu Detoxification Pill|DRUG: Entecavir or Tenofovir|DRUG: Standard - Ge Xia Zhu Yu Decoction|DRUG: Advanced - Supplemented Taohong Huazhuo Decoction|DRUG: Standard - Chaihu Shugan San|DRUG: Advanced - Soothe the liver and regulate qi Decoction|DRUG: Standard - Xiaoyao powder|DRUG: Advanced - Supplemented Ganbi Decoction|DRUG: Standard - Yiguan Decoction|DRUG: Advanced - Supplemented Zimu Dan|DRUG: Standard - Fuzilizhong Decoction plus Jinkui Shenqi Bolus|DRUG: Advanced - Guifu Erxian Decoction|DRUG: Advanced - Supplemented Ganji Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Sham Versus Mild® Procedure in Patients Diagnosed With Symptomatic Lumbar Central Canal Stenosis
Status: COMPLETED
Conditions: Lumbar Spine Stenosis Central Canal
Interventions: DEVICE: Percutaneous Lumbar Decompression|DEVICE: Sham lumbar decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Treatment With ENF (Electro Neuro Feedback) in the Reduction of Post-surgical Hematoma in Patients Undergoing Hip Replacement: Evaluation With Ultrasound Method
Status: UNKNOWN
Conditions: Post-surgical Hematoma, Hip Replacement , Surgery
Interventions: OTHER: sessions with ENF (Electro Neuro Feedback).
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optical Coherence Tomography - Rescan During Dissection of Macular Membranes
Status: UNKNOWN
Conditions: Macular Hole|Epiretinal Membrane|Traction Syndrome Vitreomacular|Proliferative Vitreoretinopathy
Interventions: PROCEDURE: Lumera Microscope with OCT RESCAN|PROCEDURE: Conventional Microscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma
Status: RECRUITING
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type|T-lymphoblastic Lymphoma
Interventions: DRUG: Linperlisib|DRUG: Camrelizumab|DRUG: Pegaspargase|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protocol Effect of Negative Pressure Drain to Reducing Surgical Site Infection in Surgical Wound of Abdominal Surgery
Status: ENROLLING_BY_INVITATION
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Negative pressure drainage|OTHER: No pressure drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Potential of a Macronutrient Balanced Normocaloric Diet to Treat Lifestyle Diseases
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Diet A|DIETARY_SUPPLEMENT: Diet B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)
Status: TERMINATED
Conditions: Short Lasting Unilateral Neuralgiform Headache Attacks
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Local Ozone Injection and Dextrose Prolotherapy Injection in Chronic Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: DRUG: Local ozon injections|DRUG: Local dextroz prolotherapy injections|OTHER: Exercise Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Head Posture Muscles, Pulmonary Capacity and Functional Capacity: a Myotonometric Assessment
Status: COMPLETED
Conditions: Forward Head Posture|Muscle Tone|Muscle Stiffnes|Muscle Elasticty|Vital Capacity
Interventions: OTHER: muscle tonus, stiffness and elasticity,six-minute walk test, Pulmonary function tests, The neck disability index
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prostatic Artery Embolization for Benign Prostatic Obstruction
Status: COMPLETED
Conditions: Hyperplasia Prostatic|Lower Urinary Tract Symptoms|Prostatic Diseases|Urological Manifestations
Interventions: PROCEDURE: Prostatic Artery Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: CTS-1027|DRUG: Pegylated interferon|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Linezolid for the Treatment of Tuberculous Meningitis
Status: COMPLETED
Conditions: Tuberculosis, Meningeal
Interventions: DRUG: LZD|DRUG: High dose RIF|DRUG: Standard dose RIF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma|Diffuse Intrinsic Pontine Glioma
Interventions: BIOLOGICAL: Dendritic cell vaccination + temozolomide-based chemoradiation|BIOLOGICAL: Dendritic cell vaccination +- conventional next-line treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABTL0812 in Pancreatic Cancer
Status: SUSPENDED
Conditions: Pancreatic Cancer
Interventions: DRUG: ABTL0812|DRUG: Gemcitabine and nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administration of Dexmedetomidine Guided by Entropy/SPI Reduce
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DRUG: Group Dex (dexmedetomidine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Conservative Treatment for Urge Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Oxybutynin chloride, extended-release, individually-titrated|BEHAVIORAL: Behavior Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Dydrogesterone as Luteal Phase Support in Natural Cycle FET
Status: RECRUITING
Conditions: Subfertility
Interventions: DRUG: Dydrogesterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NEOADjuvant Aromatase Inhibitor and Pertuzumab/Trastuzumab for Women With Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DRUG: Exemestane|DRUG: Letrozole|DRUG: Anastrozole|DRUG: Leuprolide Acetate|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DIETARY_SUPPLEMENT: ascorbic acid|DRUG: arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Induction Therapies in High Immunological Risk Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Rabbit Antithymocyte Globulin|DRUG: Velcade|DRUG: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cosmetic Outcome at 4 Months in Hand and Feet Lacerations in Children: Conservative Versus Suture Repair
Status: TERMINATED
Conditions: Laceration Repair, Children|Hand Injuries|Foot Injuries
Interventions: PROCEDURE: Suture for wound repair|DEVICE: Suture for wound repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB061 in Healthy Adult Volunteers Including Absolute Bioavailability and Food Effect
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIB061|DRUG: Placebo|DRUG: 14C-BIIB061
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radically Open Dialectical Behaviour Therapy in Patients With Anorexia Nervosa
Status: RECRUITING
Conditions: Anorexia Nervosa|Anorexia Nervosa in Remission|Anorexia Nervosa Restricting Type
Interventions: BEHAVIORAL: Radically Open Dialectical Behaviour Therapy (RO-DBT)|OTHER: Treatment As Usual|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Abiraterone Acetate/Niraparib|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Family Systems Therapy (BFST) for Teens With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Childhood Obesity
Interventions: BEHAVIORAL: BFST for Teens with Type 2 Diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Proprioceptive Neuromuscular Facilitation (PNF) Technique in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Muscle Weakness|Balance Disorders|Knee Pain|Knee Osteoarthritis
Interventions: OTHER: Hotpack|OTHER: Ultrasound|OTHER: Combine Exercise|OTHER: Repeated Contraction Exercise|OTHER: Standart Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab in Patients With Active Polyarticular Juvenile Idiopathic Arthritis
Status: COMPLETED
Conditions: Juvenile Idiopathic Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Timing of CABG in Patients Presenting With ACS and Treated With Ticagrelor
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: PRU guided CABG|PROCEDURE: CABG per standard of care|DEVICE: VerifyNow assay|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Intradermal Versus Intramuscular Administration of HIV Lipopeptides in HIV Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: Lipopeptides LIPO-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of a Vascular Venous Anastomotic Connector [InterGraft VIG-only Study]
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Venous InterGraft Connector|PROCEDURE: sutured arterial anastomosis of an implanted vascular graft for hemodialysis|PROCEDURE: hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomic Sequencing in Determining Treatment in Patients With Metastatic Cancer or Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Metastatic Neoplasm|Recurrent Neoplasm|Recurrent Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer|Stage IV Non-Small Cell Lung Cancer|Unresectable Malignant Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Targeted Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics Study of QLH11906 in Patients With Advanced Solid Tumors Harboring MAPK Pathway Alterations.
Status: RECRUITING
Conditions: Advanced Solid Tumors Harboring MAPK Pathway Alterations
Interventions: DRUG: QLH11906
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Assessment of a Multipeptide-gene Vaccine in CML
Status: COMPLETED
Conditions: Leukemia, Myeloid, Chronic
Interventions: BIOLOGICAL: Bcr-abl multipeptide vaccine|GENETIC: Cytokine gene adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE)
Status: TERMINATED
Conditions: Tumors With Aberrations in ALK or ROS1
Interventions: DRUG: Ceritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C
Status: UNKNOWN
Conditions: Hepatitis C Virus Infection|Infection|Herpesvirus 2, Human
Interventions: DRUG: Valacyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia
Status: TERMINATED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: Uproleselan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation on the Acoustic Stimulation in the Treatment of Chronic Tinnitus
Status: COMPLETED
Conditions: Chronic Tonal Tinnitus
Interventions: DEVICE: Acoustic CR-Stimulator ANM//Technology: Acoustic coordinated reset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia
Status: TERMINATED
Conditions: Hospitalized Children With Suspected or Confirmed Nosocomial Pneumonia
Interventions: DRUG: Ceftazidime-avibactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Entrapment Neuropathy, Carpal Tunnel|Compression Neuropathy, Carpal Tunnel|Median Neuropathy, Carpal Tunnel
Interventions: PROCEDURE: Median nerve decompression at the wrist|DIETARY_SUPPLEMENT: Alpha lipoic acid post median nerve decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sutures vs. Staples Skin Closure After C-section in Obese Patients
Status: TERMINATED
Conditions: Obesity|Pregnancy
Interventions: PROCEDURE: Suture vs. staples closure method after c-section in obese women.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Eltrombopag To Initiate And Maintain Interferon Antiviral Treatment To Subjects With Hepatitis C Related Liver Disease
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: eltrombopag|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cross-linking for Corneal Ulcers Treatment Trial
Status: COMPLETED
Conditions: Corneal Ulcer|Infectious Keratitis|Bacterial Ulcer|Fungal Ulcer
Interventions: PROCEDURE: Corneal Cross-linking|DRUG: Anti Fungal Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention Study With Omega-3 Fatty Acids for Weight Loss and Insulin Resistance in Adolescents
Status: COMPLETED
Conditions: Obesity|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Omega3 and an hypocaloric diet.|DIETARY_SUPPLEMENT: Sunflower oil with an hypocaloric diet.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transcranial Direct Current Stimulation as Treatment for Auditory Hallucinations
Status: UNKNOWN
Conditions: Psychotic Disorders|Mood Disorders|Personality Disorders|Stress Disorders, Post-Traumatic|Hearing Disorders
Interventions: DEVICE: Eldith DC Stimulator stimulation|DEVICE: Eldith DC Stimulator sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Replacing Red and Processed Meat With Quorn on Biomarkers of Gut Health
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: Red and Processed Meat|OTHER: Quorn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Planetary Habitat Simulation: Bone Metabolism Studies
Status: COMPLETED
Conditions: Hypoxia|Bone Resorption
Interventions: OTHER: Hypoxia|OTHER: Ambulatory|OTHER: Normoxia|OTHER: Bed Rest|OTHER: Standardised nutritional intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: HOT: HIPEC in Ovarian Cancer as Initial Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma|Ovarian Carcinoma|Fallopian Tube Carcinoma
Interventions: PROCEDURE: Cytoreductive Surgery (CRS)|DRUG: Adjuvant Chemotherapy|OTHER: Questionnaire|PROCEDURE: Hyperthermic intraperitoneal chemotherapy|DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Safety and Efficacy of Dexmedetomidine and Propofol
Status: TERMINATED
Conditions: Safety and Efficacy of Sedation Medications
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Single-blind, Randomized Study of the Safety and Efficacy of Cellularized Integra® Using Autologous Burn-derived Stem Cells
Status: NOT_YET_RECRUITING
Conditions: Burns
Interventions: DEVICE: Integra®|DEVICE: Integra®-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
Status: COMPLETED
Conditions: Pregnancy|Malaria|HIV Infections
Interventions: DRUG: Sulphadoxine-pyrimethamine|DRUG: Mefloquine (full dose)|DRUG: Mefloquine (split dose)|DRUG: placebo|DRUG: mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Annual Study to Investigate Influenza Vaccine Due to New Virus Strains for the 2007/2008 Influenza Season in Europe
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Trivalent influenza subunit vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor
Status: RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer|High Grade Serous Cancer|High Grade Endometrioid Cancer
Interventions: DRUG: Niraparib|DRUG: Dostarlimab|DRUG: Bevacizumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin-based Chemotherapy With or Without Panitumumab in Platinum-sensitive Recurrent Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: Panitumumab|DRUG: pegylated liposomal doxorubicin (PLD)|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of HIV/HCV Coinfection With Peg-IFN and Ribavirin in Patients Receiving ART Monotherapy With Lopinavir/r
Status: COMPLETED
Conditions: HIV/HCV Co-infection|HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Lopinavir/ritonavir with two nucleoside analogs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and Sorafenib as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Liver Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: sorafenib tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT