pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Double Wire Technique in Difficult Cases of Common Bile Duct Cannulation in ERCP (UDOGUIA-04)
Status: UNKNOWN
Conditions: Bile Duct Diseases
Interventions: PROCEDURE: Double guide wire technique|PROCEDURE: Standard bile duct cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: clofarabine|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Endothelium Evaluation After Phacoemulsification in Diabetec and Non-diabetic Patients With Pseudoexfoliation
Status: COMPLETED
Conditions: Pseudoexfoliation
Interventions: PROCEDURE: phacoemulsification of the lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study of Pirfenidone in Pulmonary Fibrosis With Anti-myeloperoxydase Antibodies
Status: COMPLETED
Conditions: Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial of CinnaGen COVID-19 Vaccine (SpikoGen)
Status: COMPLETED
Conditions: Covid19
Interventions: BIOLOGICAL: SARS-CoV-2 recombinant spike protein + Advax-SM adjuvant|BIOLOGICAL: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Myofunctional and Respiratory Intervention on Phonation in Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: Myofunctional and respiratory training program|OTHER: Range of motion and thermal and mechanical stimulation exercising
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Virtual Reality to Treat Gastroparesis
Status: SUSPENDED
Conditions: Gastroparesis
Interventions: DEVICE: Oculus Go VR headset|DEVICE: Sham Oculus Go VR headset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess if Epanutin Infatabs 50 mg From Germany Are Similar to Dilantin Infatabs 50 mg From Australia
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Epanutin Infatabs (Phenytoin)|DRUG: Dilantin Infatabs (Phenytoin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MRI Effects of Pegvorhyaluronidase Alfa (PEGPH20) in Pancreatic Ductal Adenocarcinoma
Status: WITHDRAWN
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Pegvorhyaluronidase alfa|DRUG: Abraxane|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Sulfonylurea|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Structure and Function in Patients With Cystic Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystic Fibrosis|Cystic Fibrosis-related Diabetes|Cystic Fibrosis, Pulmonary|Cystic Fibrosis of Pancreas|Cystic Fibrosis Gastrointestinal Disease|Cystic Fibrosis Modifier 1|Left Ventricular Dysfunction|Heart Failure|Heart Failure, Systolic|Heart Failure, Diastolic|Myocardial Infarction|Stroke|Heart Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Local Application of Platelet-rich Fibrin Scaffold Loaded With Simvastatin on Peri-implant Bone Changes
Status: COMPLETED
Conditions: Platelet-rich Fibrin|Simvastatin
Interventions: DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Brain Metastases|HER2-positive Breast Cancer
Interventions: OTHER: Pyrotinib Plus Capecitabine combined with brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AT247, NovoLog® and Fiasp® Administered Via Continuous Subcutaneous Infusion in Glucose Clamp Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: AT247|DRUG: NovoLog|DRUG: Fiasp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pregabalin Administration on Catheter- Related Bladder Discomfort in Urological Surgical Operations
Status: COMPLETED
Conditions: Pregabalin on Catheter Related Bladder Discomfort
Interventions: DRUG: Placebo oral capsule|DRUG: Pregabalin Oral Capsule [Lyrica] 75mg|DRUG: Pregabalin Oral Capsule [Lyrica] 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders.
Status: NOT_YET_RECRUITING
Conditions: Attention Deficit Disorder With or Without Hyperactivity (ADHD)|Autism Spectrum Disorder (ASD)
Interventions: BEHAVIORAL: Trier Social Stress Task
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder
Interventions: DRUG: Nitrous Oxide 99 %|DRUG: Oxygen + Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Photobiomodulation Therapy in a Field Test With High-level Rugby Players
Status: COMPLETED
Conditions: High-level Rugby Athletes|Performance|Recovery
Interventions: DEVICE: Photobiomodulation therapy (Phototherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Physical Function, Health and Employment for People With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: CoreDISTParticipation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tapinarof for the Treatment of Atopic Dermatitis in Children and Adults
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: tapinarof cream, 1%|DRUG: Vehicle cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome|Pregnancy Related|Sleep Disorder
Interventions: DEVICE: Compression stocks|OTHER: Knee socks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Management of Chronic Non-Cancer Pain With Non-Pharmacological Therapies
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain Syndrome|Sensitization, Central|Quality of Life|Patient Empowerment
Interventions: BEHAVIORAL: Chronic Pain Management Workshop with Non-Pharmacological Therapies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Videogame Based Dance Training With Agility Ladder Drills on Agility of Volleyball Players
Status: COMPLETED
Conditions: Healthy Athletes
Interventions: DEVICE: XBOX Kinect Just Dance 2014|OTHER: Agility Ladder Drills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Impact of Del Nido Cardioplegia in Adult Cardiac Surgery
Status: UNKNOWN
Conditions: Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: DRUG: DEL NIDO CARDIOPLEGIA|DRUG: COLD BLOOD BASED CARDIOPLEGIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Total vs Partial Fundoplication in Patients With Atypical Symptoms of Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Laparoscopic fundoplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: STELLAREX: ILLUMENATE Global and In-Stent Restenosis (ISR)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Stellarex 0.035" Over-the-Wire (OTW) drug-coated angioplasty balloon (Stellarex DCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional Freedom Technique (EFT) on Pain and Stress Levels in Fibromyalgia (FMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Emotional Freedom Technique (EFT) works on cognitive and energetic levels.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective, Randomized Study of Operative and Nonoperative Treatment for Primary Traumatic Patellar Dislocation
Status: COMPLETED
Conditions: Patellar Dislocation
Interventions: PROCEDURE: proximal patellar surgery|PROCEDURE: Nonoperative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Novel Vaccine Formulation MV-ZIKA-RSP (V187-001)
Status: COMPLETED
Conditions: Zika Virus Infection
Interventions: BIOLOGICAL: Two MV-ZIKA-RSP vaccinations (high dose)|BIOLOGICAL: Two MV-ZIKA-RSP vaccination (low dose)|BIOLOGICAL: One MV-ZIKA-RSP vaccination (high dose) and one placebo|OTHER: Two placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease
Status: WITHDRAWN
Conditions: Thyroid Eye Disease
Interventions: DRUG: Methylprednisolone + ASTED|DRUG: Methylprednisolone +Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver Metastases
Status: COMPLETED
Conditions: Liver Metastasis|Colorectal Neoplasms|Liver Neoplasms|Neoplasm Metastasis
Interventions: DRUG: Talaporfin sodium (LS11)|DEVICE: LED-based light infusion device|DEVICE: Light emitting diodes (LED)|PROCEDURE: Photodynamic therapy|PROCEDURE: Phototherapy|PROCEDURE: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of POC-A1c vs the Current Standard Based on OGTT for Early Detection DM2 in Colombia
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Point of Care - Glycated Hemoglobin (A1c)|OTHER: Oral Glucose Tolerance Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Odansetron and Dexamethasone Alone vs. Odansetron, Dexamethason and Apreptant to Prevent Nausea
Status: COMPLETED
Conditions: Nausea|Vomiting
Interventions: DRUG: Standard PO (Zofran + Dexamethason)|DRUG: Aprepitant (MK-869) + Standard PO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Study of (Parlodel®) Bromocriptine Mesylate Capsules 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BROMOCRIPTINE MESYLATE CAPSULES, USP 5 mg|DRUG: Parlodel® (bromocriptine mesylate) capsules, USP 5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Dexmedetomidine VS Magnesium Sulphate With Bupivacaine in Erector Spinae Block for Thoracotomy Pain
Status: RECRUITING
Conditions: Analgesia
Interventions: DRUG: Bupivacaine|DRUG: Bupivacaine + Magnesium|DRUG: Bupivacaine + Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Paravertebral Block in Cancer Surgery of the Lung
Status: RECRUITING
Conditions: Thoracic Neoplasm|Chronic Pain Post-Procedural|Acute Post-thoracotomy Pain|Anesthesia, Local
Interventions: DRUG: Levo-Bupivacaine Hydrochloride (HCl) 0.5 % in 20mL Injection|DRUG: 0.9% Sodium Chloride 20mL Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Propofol Requirement During Anesthesia
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine|DRUG: Placebo (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interferon-alfa With or Without Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: busulfan|DRUG: cytarabine|DRUG: etoposide|DRUG: hydroxyurea|DRUG: idarubicin|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Prevention of Esophageal Varices|NASH - Nonalcoholic Steatohepatitis|Cirrhosis
Interventions: DRUG: belapectin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Transversus Abdominis Plane Block Versus Wound Infiltration for Analgesia After Cesarean Delivery:
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: DEVICE: TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Menthol Flavored E-cigarette Use During a Simulated Ban of Menthol Cigarettes
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: OTHER: menthol flavored e-cigarette|OTHER: tobacco flavored e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Magnesium Sulfate Effects on Onset and Duration of Low Dose Rocuronium in Patients Undergoing Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Muscle Relaxation
Interventions: DRUG: Magnesium Sulfate|DRUG: Saline|DRUG: Standard dose Rocuronium|DRUG: Low dose Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety for 'IL-YANG Quadrivalent Influenza Vaccine' in Healthy Korean Children and Adolescents
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: IL-YANG Quadrivalent Influenza Vaccine|BIOLOGICAL: IL-YANG Flu Vaccine Pre-filled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exenatide on Glucose Homeostasis Determinants in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide (Byetta)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos
Status: RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: BEHAVIORAL: COVID Prevention Program (CPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Efficacy of Synvisc in Patients With Symptomatic Ankle Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Synvisc (hylan G-F 20)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of Rosiglitazone (Extended Release Tablets) On Cerebral Glucose Utilisation And Cognition Alzheimers Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rosiglitazone XR (extended release) oral tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of 10 mg Teduglutide in Subjects With Renal Impairment Compared to Healthy Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Teduglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Narrative Group Counseling and Psychological Resilience
Status: COMPLETED
Conditions: Psychological Resilience
Interventions: OTHER: Narrative Group Counseling|OTHER: stress coping interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Intravitreal Erythropoietin Injection for Refractive Diabetic Macular Edema
Status: UNKNOWN
Conditions: Refractory Diabetic Macular Edema
Interventions: DRUG: injection of bevacizumab and erythropoietin|DRUG: injection of bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Onabotulinumtoxin A Versus Kenalog for Chronic Pelvic Pain
Status: COMPLETED
Conditions: Pelvic Pain
Interventions: DRUG: Onabotulinumtoxin A|DRUG: Kenalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction With Initial Phone Call Versus Office Visit Following Minimally Invasive Hysterectomy, a Randomized Controlled Trial.
Status: COMPLETED
Conditions: Abnormal Uterine Bleeding
Interventions: OTHER: phone call follow up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?
Status: COMPLETED
Conditions: Congestive Heart Failure|Infections|Sepsis|Acute Renal Failure|Stroke
Interventions: OTHER: Script and CPR/Mechanical ventilation video.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Factors Influencing of Pulse Pressure Variation (PPV)
Status: COMPLETED
Conditions: Haemodynamics|Fluid Responsiveness|Pulse Pressure Variation
Interventions: DEVICE: Patients were ventilated with assist-control ventilation（A/C） mode at different tidal volume|BEHAVIORAL: spontaneous breathing and no spontaneous breathing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: DFP-10917|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
Status: COMPLETED
Conditions: Siewert Type I-II Adenocarcinoma of the Esophagus
Interventions: PROCEDURE: esophagectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant
Status: RECRUITING
Conditions: Dental Implant|Surgical Dental Prostheses|Dental Implantation
Interventions: DEVICE: Low intensity pulsed ultrasound (LIPUS)|DEVICE: low level diode laser therapy|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PILOT STUDY OF THE EFFICACY AND SAFETY OF WF10 IN SUBJECTS SUFFERING FROM PERSISTENT ALLERGIC RHINITIS
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: WF10|DRUG: NaCl Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Guided Bone Marrow Biopsy vs Trephine Bone Marrow Biopsy
Status: COMPLETED
Conditions: Lymphoma|Bone Marrow Neoplasm
Interventions: PROCEDURE: PET Guided Bone Marrow Biopsy|PROCEDURE: Trephine Bone Marrow Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of the Minimum Bronchial Cuff Volume of Left-sided Double-lumen Endotracheal Tube for One-lung Ventilation on the Change of the Bronchial Cuff Pressure During Lateral Positioning in Thoracic Surgery
Status: COMPLETED
Conditions: Lung Cancer|Pneumothorax
Interventions: BEHAVIORAL: Lateral positioning|DEVICE: Cuff pressure measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma
Status: COMPLETED
Conditions: CD20+, B-cell Lymphomas|Mantle Cell Lymphoma|Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL)|Transformed Lymphoma/DLBCL/PMBCL|Hodgkin's Disease|Gray Zone Lymphoma
Interventions: DRUG: Everolimus|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Telbivudine to Prevent Perinatal Transmission
Status: UNKNOWN
Conditions: Chronic Hepatitis B, Gestation
Interventions: DRUG: Telbivudine|BIOLOGICAL: engineered HB vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Hydroxypropyl Guar Galactomannan 0.25% (HPGG) Versus Vehicle in Dry Eye Patients
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Hydroxypropyl Guar Galactomannan (HPGG) 0.25% ophthalmic gel|DRUG: Hydroxypropyl Guar Galactomannan Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Satisfaction With Contraceptive Counseling Using Telephone Versus Video Telehealth Visits
Status: UNKNOWN
Conditions: Contraception|Health Care Utilization
Interventions: OTHER: Contraceptive Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Genetic Polymorphisms of TNF-α Promoter and HBV Genotype on Outcome of HBV-Related Chronic Liver Disease
Status: UNKNOWN
Conditions: Chronic Liver Disease|Hepatocellular Carcinoma
Interventions: GENETIC: TNF-alpha and HBV genotype|OTHER: TNF-alpha and HBV genotypes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Efficacy of THR-317 for the Treatment of Diabetic Macular Oedema (DME)
Status: COMPLETED
Conditions: Diabetic Retinopathy|Macular Edema
Interventions: DRUG: Anti-PlGF recombinant monoclonal antibody, 4mg dose|DRUG: Anti-PlGF recombinant monoclonal antibody, 8mg dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: imatinib mesylate|DRUG: temozolomide|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Lipopolysaccharide on Skeletal Muscle Functions
Status: COMPLETED
Conditions: Sepsis
Interventions: BIOLOGICAL: Lipopolysaccharide infusion|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CNCT19 for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.
Status: RECRUITING
Conditions: Autoimmune Hemolytic Anemia|Autologous CD19 CAR-T|Failure of Three or More Lines of Therapy
Interventions: BIOLOGICAL: CNCT19 CAR-T cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TQ-B3525 in Subjects With Relapsed/Refractory Peripheral T-cell Lymphoma（PTCL）
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: TQ-B3525
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Changes in Early Parkinson's Disease: A Follow up Study
Status: ENROLLING_BY_INVITATION
Conditions: REM Sleep Behavior Disorder|Pre-motor Parkinson Disease|Symptomatic Parkinson Disease
Interventions: DRUG: Carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sarcopenia on the Occurrence of Toxicity Related to Anti-cancer Treatments
Status: RECRUITING
Conditions: Sarcopenia|Oncology|Physical Inactivity|Toxicity Due to Chemotherapy
Interventions: DIAGNOSTIC_TEST: Sarcopenia diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: BRII-835 (VIR-2218)|BIOLOGICAL: BRII-179 (VBI-2601) with IFN-α|BIOLOGICAL: BRII-179 (VBI-2601)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photophoresis Versus Ciclosporine in Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Cyclosporine A (CsA)|OTHER: Extracorporeal photopheresis (ECP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Automated Closed-loop in Children and Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Endocrine System Diseases|Autoimmune Diseases
Interventions: DEVICE: Closed-loop (Android Closed-Loop platform)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Hypoglycemia During Exercise With Proactive Snacking on Closed Loop
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Medtronic MiniMed Closed Loop (CL) System|OTHER: Snacking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors
Status: COMPLETED
Conditions: Fractures, Bone
Interventions: BIOLOGICAL: Denosumab 70 mg/mL|DRUG: Zoledronic acid 4 mg|DRUG: Placebo IV|DRUG: Placebo SC|DIETARY_SUPPLEMENT: Calcium supplement|DIETARY_SUPPLEMENT: Vitamin D supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combined PEV3A Virosomal Vaccine and FP9-MVA ME-TRAP Prime Boost Regimen
Status: COMPLETED
Conditions: Malaria|Malaria, Falciparum
Interventions: BIOLOGICAL: PEV3A|BIOLOGICAL: FP9 ME-TRAP|BIOLOGICAL: MVA ME-TRAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Plus Cisplatin as First-Line Treatment in Stage IV or Recurrence of Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xian-Hua-Cha for Relieving Hyperlipidemia With Obesity
Status: RECRUITING
Conditions: Hyperlipidemias|Obesity|Body Fat Disorder
Interventions: DRUG: Xian-Hua-Cha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Early Postoperative Treatment With Posterior Tibial Nerve Stimulation on the Incidence and Duration of Low Anterior Rectal Resection Syndrome
Status: RECRUITING
Conditions: Rectal Disorders|Low Anterior Resection Syndrome|Low Anterior Resection
Interventions: DEVICE: Posterior tibial nerve stimulation (PTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Estimate The Effect Of Repeated Dosing of PF-05175157 On The Pharmacokinetics Of A Single Dose Of Simvastatin In Healthy Adult Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Simvastatin|DRUG: PF-05175157
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: AT9283 in Children and Adolescents With Relapsed and Refractory Solid Tumors
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: multikinase inhibitor AT9283|OTHER: enzyme-linked immunosorbent assay|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growth Factors in the Localized Gingival Recessions Treatment
Status: COMPLETED
Conditions: Localized Gingival Recession
Interventions: PROCEDURE: Concentrated Growth Factor Membrane|PROCEDURE: Platelet Rich Fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab in Hemorrhagic Choroidal Neovascularization Trial
Status: COMPLETED
Conditions: Choroidal Neovascularization
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of RIRS Versus PCNL Methods, According to Postoperative Pain and Analgesic Demand in 2 to 4 cm Renal Stones
Status: UNKNOWN
Conditions: Kidney Stones
Interventions: PROCEDURE: Percutaneous nephrolithotomy|PROCEDURE: Retrograde intrarenal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Kidney Transplant
Status: WITHDRAWN
Conditions: Kidney Failure|Kidney Diseases|Hepatitis C
Interventions: DRUG: glecaprevir/pibrentasvir tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombinant Von Willebrand Factor in Subjects With Severe Von Willebrand Disease Undergoing Surgery
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: BIOLOGICAL: Recombinant von Willebrand Factor (rVWF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using AR Dental Care Training System in HE on Periodontal Status, Blood Sugar Control and QoL in Patients With T2DM
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2 With Periodontal Disease
Interventions: DEVICE: AR Dental Care Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: ABSORB Bioresorbable Scaffold vs. Xience Metallic Stent for Prevention of Restenosis in Patients at High Risk of Restenosis
Status: UNKNOWN
Conditions: Coronary Artery Lesion
Interventions: DEVICE: ABSORB scaffold|DEVICE: Xience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comprehensive Practice-Friendly Model for Promoting Healthy Behaviors
Status: COMPLETED
Conditions: Unhealthy Diet, Exercise, Smoking, and Alcohol Use
Interventions: BEHAVIORAL: Computer based care|BEHAVIORAL: Telephone counseling|BEHAVIORAL: Group visits|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis
Status: COMPLETED
Conditions: Meningitis, Cryptococcal|HIV Infections
Interventions: DRUG: Fluconazole|DRUG: Amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Changes in Bone Turnover With Increased Incretin Hormone Exposure
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nocturnal Nasal Continuous Positive Airway Pressure in Aspiration Pneumonia
Status: WITHDRAWN
Conditions: Aspiration Pneumonia
Interventions: DEVICE: nocturnal nasal continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Bladder Neoplasms
Interventions: DRUG: Mycobacterial cell wall-DNA complex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Upper and Lower Extremity Endurance Training in Patients With ICD
Status: UNKNOWN
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: OTHER: bicycle ergometer and arm ergometer exercise|OTHER: bicycle ergometer exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Negative Pressure Wound Therapy and Allogeneic Human Skin Grafts for Wound Bed Preparation
Status: WITHDRAWN
Conditions: Necrotizing Soft Tissue Infection
Interventions: PROCEDURE: Negative pressure wound therapy|PROCEDURE: Glycerol Preserved Allografts (GPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Mass Balance Study With C14 - Labeled AAI101 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 1 µCi of 14C-AAI101 + 500 mg AAI101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vivomixx for Prevention of Bone Loss in Women With Breast Cancer Treated With an Aromatase Inhibitor
Status: UNKNOWN
Conditions: Breast Cancer|Osteoporosis, Osteopenia
Interventions: DRUG: Vivomixx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pinhole Surgical Technique With And Without Use Of Buttons For Treatment Of Multiple Gingival Recessions: RCT
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: Pinhole surgery with and without buttons
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Social Media And Risk-reduction Training for Infant Care Practices (SMART)
Status: COMPLETED
Conditions: Risk Reduction
Interventions: BEHAVIORAL: Safe Sleep Nursery Education|BEHAVIORAL: Breastfeeding Nursery Education|BEHAVIORAL: Breastfeeding Mobile Health Messaging|BEHAVIORAL: Safe Sleep Mobile Health Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Mind-Body Interventions for Frequent Attendees Suffering From Medically Unexplained Symptoms (MUS)
Status: TERMINATED
Conditions: Neurasthenia|Chronic Pain|Chronic Headache
Interventions: OTHER: Medical and Psychological treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D-vitamin And Graves' Disease; Morbidity And Relapse Reduction
Status: COMPLETED
Conditions: Graves' Disease
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclosporine In Takotsubo Syndrome
Status: NOT_YET_RECRUITING
Conditions: Takotsubo Cardiomyopathy
Interventions: DRUG: Cyclosporine A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LEO 22811 - A Phase 1, Double-Blind, Placebo-controlled, Single and Multiple Oral Dose Study in Healthy Subjects
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 22811|DRUG: placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Omacetaxine in Patients With Intermediate-1 and Higher Risk Myelodysplastic Syndrome (MDS) Post Hypomethylating Agent (HMA) Failure
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Omacetaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Skipping Breakfast on Metabolic Function
Status: COMPLETED
Conditions: Skipping Breakfast|Circadian Rhythms
Interventions: OTHER: 3 standard meals/day|OTHER: 2 meals/day (omit breakfast)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants
Status: UNKNOWN
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Oral paracetamol|DRUG: Oral ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial for Single Port Versus Conventional Laparoscopic Colectomy
Status: UNKNOWN
Conditions: Colonic Polyps|Colonic Cancers
Interventions: PROCEDURE: Single port laparoscopic colectomy|PROCEDURE: Conventional laparoscopic colectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Treatment Once a Month Versus Once a Week for Posture Improvement in Children and Adolescents
Status: COMPLETED
Conditions: Postural Kyphosis, Thoracic Region
Interventions: OTHER: Physical Therapy treatment for Postural Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Revlimid in Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Revlimid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of CIRC Technologies
Status: RECRUITING
Conditions: Cardiovascular Diseases|Heart Failure|Ischemic Heart Disease|Non-ischemic Cardiomyopathy|Valvular Heart Disease|Metabolic Cardiomyopathy|Congenital Heart Disease|Aortic Diseases|Atrial Fibrillation|Ventricular Fibrillation
Interventions: DIAGNOSTIC_TEST: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of a Probiotic Intervention in Healthy Subjects and Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DIETARY_SUPPLEMENT: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOFIA-LTT Study: A Study of Intermittent Long Term Treatment With PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Negative Chronic Hepatitis B (CHB).
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: PEGASYS [peginterferon alfa-2a]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy
Status: WITHDRAWN
Conditions: Cholecystitis, Acute|Cholecystitis; Gallstone
Interventions: PROCEDURE: Stent removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Assisted Ventilation Mode on Diaphragm Efficiency in Critically Ill Patients
Status: COMPLETED
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Pressure Support ventilation|DEVICE: Neurally Adjusted Ventilatory Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Montelukast in Asthma in Children
Status: UNKNOWN
Conditions: Bronchial Asthma
Interventions: DRUG: Montelukast sodium.|DRUG: Placebo tablet and budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DEVICE: NovoTTF-200T|DRUG: Pembrolizumab (MK-3475) 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Physical Activity Levels of Patients Following HTO.
Status: SUSPENDED
Conditions: High Tibial Osteotomy With Allograft Wedge|High Tibial Osteotomy Without Allograft Wedge|Pre- and Post-operative Physical Activity Levels
Interventions: PROCEDURE: High tibial osteotomy|DEVICE: Allograft wedge|DEVICE: Accelerometer|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds
Status: COMPLETED
Conditions: Wound of Skin|Wound Heal|Wound Open|Surgical Wound
Interventions: DRUG: 0.25% Timolol gel with paraffin gauze dressings|OTHER: Vaseline dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT