pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: AMPLIFY - D6571C00001 Duaklir USA Phase III Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium bromide 400 μg/Formoterol Fumarate 12 μg (AB/FF 400/12 μg)|DRUG: Aclidinium bromide 400 μg (AB 400 μg)|DRUG: Formoterol fumarate 12 μg (FF 12 μg)|OTHER: Placebo to AB/FF 400/12 μg, AB 400 μg and FF 12 μg|DRUG: Tiotropium 18 μg (TIO 18 μg)|OTHER: Placebo to TIO 18 μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Using Transcranial MR Guided Focused Ultrasound in the Treatment of Neuropathic Pain
Status: UNKNOWN
Conditions: Functional Brain Disorders /Neuropathic Pain
Interventions: DEVICE: ExAblate 4000 focused ultrasound brain intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Satisfactory Analgesia Minimal Emesis in Day Surgeries
Status: COMPLETED
Conditions: Pain|Post Operative Nausea and Vomiting
Interventions: DRUG: Morphine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: THP Hip Fracture Plating System Study
Status: TERMINATED
Conditions: Femur Fracture|Femur Fracture Intertrochanteric|Garden Grade I Subcapital Fracture of Femoral Neck|Garden Grade II Subcapital Fracture of Femoral Neck|Garden Grade III Subcapital Fracture of Femoral Neck|Garden Grade IV Subcapital Fracture of Femoral Neck
Interventions: DEVICE: THP Hip Fracture Plating System with telescoping lag screws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03)
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Rapastinel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Study to Evaluate the Efficacy and Safety of KX2-391 Ointment 1% on AK on Face or Scalp
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Placebo|DRUG: KX2-391 Ointment 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nocturnal Hypertension and Non-Dipping Blood Pressure
Status: COMPLETED
Conditions: Hypertension|Obstructive Sleep Apnea
Interventions: DIETARY_SUPPLEMENT: Dietary sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Human Umbilical Cord Stroma MSC in Myocardial Infarction
Status: TERMINATED
Conditions: Chronic Ischemic Cardiomyopathy|Coronary Artery Bypass Surgery
Interventions: BIOLOGICAL: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDD
Status: RECRUITING
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: REL-1017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Safety Tolerability, Pharmacokinetics And Midazolam Interaction In Healthy Overweight And Obese Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: PF-05175157|DRUG: Midazolam|OTHER: Placebo|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute and Chronic Protective Effects of Peri-interventional Administration of Levosimendan in ST Elevation Myocardial Infarctions
Status: WITHDRAWN
Conditions: Myocardial Infarction|Outcome
Interventions: DRUG: Levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Aromatherapy Massage in Menopausal Women With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Bergamot|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Manipulation vs. Mobilization, Exercise and Interferential Electrotherapy for Shoulder Impingement (Subacromial Pain Syndrome)
Status: COMPLETED
Conditions: Subacromial Pain Syndrome
Interventions: OTHER: dry needling|OTHER: spinal manipulation|OTHER: mobilization|OTHER: exercise|OTHER: modalities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Next4You: A Fully Mobile Relationships Based Program for Youth in Foster Care
Status: ENROLLING_BY_INVITATION
Conditions: Pregnancy Related|Adolescent Behavior|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Next4You
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Fatty Liver|Liver Fibrosis|Obesity|Metabolic Syndrome|Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Docosahexaenoic Acid plus Vitamin E plus choline|DRUG: placebo pearls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Opioid Use
Interventions: OTHER: Decreased opiate prescription|OTHER: Routine opiate prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography for Intracranial Atherosclerotic Stenosis
Status: RECRUITING
Conditions: Intracranial Atherosclerosis|Optical Coherence Tomography|Plaque, Atherosclerotic|Artery Stenosis|Ischemic Stroke
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography|PROCEDURE: Percutaneous transluminal angioplasty and stenting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Preliminary Efficacy of Sequential Multiple Ascending Doses of Solnatide to Treat Pulmonary Permeability Oedema in Patients With Moderate-to-severe ARDS
Status: RECRUITING
Conditions: ARDS
Interventions: DRUG: Solnatide 25 mg powder for reconstitution for solution for inhalation|DRUG: 0.9% Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Change Esophagitis by i-Scan Endoscopy in Dyspeptic Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Patients with GerdQ positive|PROCEDURE: Patients with GerdQ negative|PROCEDURE: Normal volunteers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LJPC-501 in Pediatric Patients With Hypotension
Status: COMPLETED
Conditions: Catecholamine-resistant Hypotension (CRH)|Distributive Shock|High Output Shock|Sepsis
Interventions: DRUG: Angiotensin II
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol 20% for Separation of Pterygium and Comparison of Different Wound Closure Methods
Status: UNKNOWN
Conditions: Pterygium
Interventions: PROCEDURE: pterygium surgery using alcohol 20% for tissue separation and bare sclera as wound closure technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of PDI-320 in Comparison to Its Monads in Adults With Rosacea
Status: UNKNOWN
Conditions: Rosacea
Interventions: DRUG: PDI-320|DRUG: PDI-320 Monad #1|DRUG: PDI-320 Monad #2|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: CLIC-1901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
Status: RECRUITING
Conditions: Myocardial Infarction|Ischemia|Myocardial Ischemia|Heart Diseases|Cardiovascular Diseases|Vascular Diseases|Heart Attack|Heart Failure
Interventions: DEVICE: AliveCor 12-lead ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-Intensity Interval Training for Stage I-III Breast Cancer Patients
Status: TERMINATED
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Safety and Efficacy of Elagolix in Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Elagolix|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gas Tamponade for Prevention of Postoperative Vitreous Hemorrhage in Diabetics
Status: ACTIVE_NOT_RECRUITING
Conditions: Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: vitrectomy with sulfur hexafluoride gas|PROCEDURE: vitrectomy with balanced salt solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bilateral Distalization of Upper First Molars in a Group of Patients After Extraction of Maxillary Second Molars
Status: COMPLETED
Conditions: Class II Malocclusion
Interventions: DEVICE: Intra-Oral Distalizing Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trans-diagnostic Cognitive-behavioral Therapy for Treatment of Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: BEHAVIORAL: Trans-diagnostic cognitive-behavioral therapy|BEHAVIORAL: General relaxation/stress management therapeutic session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
Status: COMPLETED
Conditions: Tourette Syndrome|Tic Disorders
Interventions: BEHAVIORAL: Comprehensive Behavioral Intervention for Tics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED)
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: timolol/dorzolamide combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Energy Density on Energy Intake During Bed Rest
Status: ENROLLING_BY_INVITATION
Conditions: Bed Rest|Space Analogue
Interventions: OTHER: Dietary intervention with manipulation of the energy density
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Atezolizumab|DRUG: Hu5F9-G4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postural Stability Deficiencies in Asymptomatic Individuals With HIV
Status: COMPLETED
Conditions: HIV|Balance|Vestibular Disorder|Somatosensory Disorders|Postural Stability
Interventions: OTHER: Postural Stability Testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Message Framing for Telephone Quitline Callers
Status: COMPLETED
Conditions: Smoking|Nicotine Dependence
Interventions: BEHAVIORAL: Gain-Framed counseling & Gain-framed materials|BEHAVIORAL: Standard care counseling + standard materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Clinical and Radiographic Images in Dental Implants Rehabilitated With Overdentures
Status: COMPLETED
Conditions: Failure of Dental Implant Due to Lack of Attached Gingiva|Failure of Dental Prosthesis Causing Loss of Dental Implant
Interventions: OTHER: peri-implant examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Melatonin for Treatment of Delirium in Critically Ill Adult Patients
Status: RECRUITING
Conditions: Delirium
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cervical/Thoracic Neuromodulation and Nociceptive Processing
Status: RECRUITING
Conditions: Nociceptive Pain
Interventions: DEVICE: cervical a-tsDCS|DEVICE: thoracic a-tsDCS|DEVICE: sham tsDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase III Study of Hemospan® for Treating Hypotension in Hip Arthroplasty
Status: COMPLETED
Conditions: Hypotension|Ischemia
Interventions: DRUG: Hemospan (MP4OX)|DRUG: Voluven (HES 130/0.4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrotherapy in Premature Infants With Bronchopulmonary Dysplasia
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Hydrotherapy|PROCEDURE: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Traumeel®S Tablets on Recovery and Inflammatory Immune Response After Repeated Bouts of Exercise
Status: COMPLETED
Conditions: Exercise-induced Muscle Soreness
Interventions: DRUG: Traumeel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Extracorporeal Shock Wave Therapy in Carpal Tunnel Syndrome
Status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Low dose ESWT application|PROCEDURE: High dose ESWT application|PROCEDURE: Sham ESWT|PROCEDURE: Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Aortic Stenosis, Severe
Interventions: DRUG: Levosimontane injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SOX Sequential S-1 in Advanced Biliary Tract Carcinoma（BTC）and Pancreatic Cancer
Status: UNKNOWN
Conditions: Biliary Tract Cancer|Periampullary Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: SOX sequential S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enantyum® IV Versus Piroxen® IM in Emergency Pain Management
Status: RECRUITING
Conditions: Traumatic Injury
Interventions: DRUG: Dexketoprofen|DRUG: Piroxicam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Optimal Intervention Time of Radiotherapy for Oligometastatic Stage IV Non-small Cell Lung Cancer（NSCLC）
Status: UNKNOWN
Conditions: Oligo-metastatic Stage IV Non-small Cell Lung Cancer
Interventions: RADIATION: concurrent chemoradiotherapy|DRUG: Docetaxel|DRUG: pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Prehabilitation in Pancreatic Resection
Status: COMPLETED
Conditions: Preoperative Physical Exercise Training|Aerobic Capacity|Aerobic Fitness|Functional Mobility|Cancer|Weight, Body|Cancer of Pancreas
Interventions: PROCEDURE: Home-based prehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Pain and Inflammation After Injection of Lucentis vs Eylea for Treatment of Wet Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-Related Macular Degeneration
Interventions: DRUG: Ranibizumab 0.5mg|DRUG: Aflibercept 2.0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IDP 118 in the Treatment of Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: IDP-118 Lotion|DRUG: IDP-118 Monad HP Lotion|DRUG: IDP-118 Monad Taz Lotion|DRUG: IDP-118 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attentional Mechanisms in SCD
Status: NOT_YET_RECRUITING
Conditions: Subjective Cognitive Decline
Interventions: DRUG: Mecamylamine Challenge|OTHER: Placebo Comparator Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Modified Gegen Qinlian Decoction for Diarrhea-predominant Irritable Boewl Syndrome
Status: UNKNOWN
Conditions: Diarrhea-predominant Irritable Boewl Syndrome
Interventions: DRUG: Modified Gegen Qinlian Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Instrumented Assisted Soft Tissue Mobilization On Pain, Function And Proprioception In Patients With Shoulder Impingement Syndrome
Status: UNKNOWN
Conditions: Shoulder Impingement
Interventions: OTHER: instrumented assisted soft tissue mobilization|OTHER: traditional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation With or Without Stromagen Following Chemotherapy in Treating Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: in vitro-treated bone marrow transplantation|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Drug Use Survey (DUS) of Triple Therapy (Methycobal (MBL)+ Myonal (MYO)+ Non-steroidal Anti-inflammatory Drags (NSAID)) on the Symptom Relief of Lumbar DDD in China
Status: COMPLETED
Conditions: Lumbar Disc Degenerative Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Retrograde Autologous Priming on the Coagulation Profile Assessed by Rotation Thromboelastometry (ROTEM) in Patients Undergoing Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Vascular Surgery Using CPB
Interventions: PROCEDURE: Conventional crystalloid solution-based priming|PROCEDURE: Retrograde autologous priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: We The Village Family Support Study
Status: COMPLETED
Conditions: Community Reinforcement And Family Training|Family Health|Substance-Related Disorders
Interventions: BEHAVIORAL: Community Reinforcement And Family Training (CRAFT)|BEHAVIORAL: We The Village Peer Community Forum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate Arbaclofen ER Tablets for the Treatment of Spasticity in Patients With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Spasticity
Interventions: DRUG: Arbaclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Magnetic Tape Over Hip Cutaneous Nerves in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DEVICE: Magnetic tape|DEVICE: Kinesiology tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SYSTANE Ultra Lubricant Eye Drops
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: SYSTANE Ultra|OTHER: Optive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of GM-CT-01 With and Without 5-Fluorouracil in Patients With Solid Tumors
Status: COMPLETED
Conditions: Colorectal Cancer|Lung Cancer|Breast Cancer|Head and Neck Cancer|Prostate Cancer
Interventions: DRUG: GM-CT-01|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation Between Intraocular Pressure Lowering Effects of Topical Brimonidine and Alpha 2 Receptor Polymorphism
Status: WITHDRAWN
Conditions: Ocular Physiology|Intraocular Pressure
Interventions: DRUG: Brimonidine 0.2 %
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Antibiotic Therapy Alone or Combined With Corticosteroids for the Treatment of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis in Children: A Randomized Double-Blind Placebo-Controlled Study
Status: WITHDRAWN
Conditions: Nontuberculous Mycobacterial Lymphadenitis.
Interventions: DRUG: Methylprednisoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals?
Status: COMPLETED
Conditions: HIV Infection|Herpes Simplex Type II|HIV Infections
Interventions: DRUG: valacyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Scleroderma
Interventions: BIOLOGICAL: CABA-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 60 Years and Above
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF3 OA investigational vaccine|BIOLOGICAL: FLU-QIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First Heroes: Engaging Fathers in the First 1000 Days
Status: COMPLETED
Conditions: Obesity, Childhood|Overweight and Obesity|Social Determinants of Health|Physical Activity|Feeding Behavior|Sleep|Diet Habit
Interventions: BEHAVIORAL: New Parent Intervention|BEHAVIORAL: Safety Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: MONitoring Sedentary Behavior and Light Physical Activity in Patients With Stroke
Status: RECRUITING
Conditions: Stroke, Acute|Behavior|Physical Inactivity|Sedentary Behavior
Interventions: BEHAVIORAL: Everyday Life is Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse
Status: COMPLETED
Conditions: Antisocial Behavior
Interventions: BEHAVIORAL: Multisystemic Therapy-Emerging Adults|BEHAVIORAL: Enhanced Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Music Therapy Experiences in Patients With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
Status: RECRUITING
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Home-based MT through Supervised, Supported Singing (H3S)|BEHAVIORAL: Individualized Music Therapy (IMT)|OTHER: Attention Control (AtCon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rosuvastatin in Diabetic Polyneuropathy: A Phase IIa Randomized Double-blind Placebo-controlled Study
Status: COMPLETED
Conditions: Diabetic Polyneuropathy
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing Diabetes
Status: COMPLETED
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Registered Dietitian/Nutritionist|BEHAVIORAL: Diabetes Prevention Program|BEHAVIORAL: Weight Watchers, Reimagined|BEHAVIORAL: DPP or RDN Counseling + Medication|OTHER: Bariatric Surgery Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pivotal Efficacy Trial to Evaluate HLD200 in Children With ADHD in a Classroom Setting
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: HLD200 methylphenidate hydrochloride (MPH) Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiologic Effects of RBC Transfusion
Status: TERMINATED
Conditions: Red Blood Cell Transfusion
Interventions: BIOLOGICAL: Fresh red blood cell (RBC) transfusion|BIOLOGICAL: Storage-aged red blood cell (RBC) transfusion|DEVICE: Electronic infusion pump
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Open Label Dose Escalation Study for the Safety and Tolerability of AZD2171 in Solid Tumors in Japan
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: AZD2171
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Subhypnotic Propofol for Nausea and Vomiting During for Cesarean Section Under Subarachnoid Anesthesia.
Status: COMPLETED
Conditions: PREGNANCY
Interventions: DRUG: PROPOFOL|DRUG: METOCLOPRAMIDE|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2020-2021 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively
Status: COMPLETED
Conditions: Influenza Immunization|Healthy Volunteers
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2020-2021 formulation|BIOLOGICAL: Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2020-2021 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Olanzapine on Sleep Electroencephalogram (EEG) in Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia|Sleep
Interventions: DRUG: Olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dapagliflozin Efficacy and Action in PCOS
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Maxillary Sinus (Linear and Volumetric Measurements) and Midface Width Using CBCT
Status: NOT_YET_RECRUITING
Conditions: Cone-beam Computed Tomography|Maxillary Sinus|Midface|Volumetric Analysis
Interventions: RADIATION: CBCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise, Hypertension, and Gut Dysbiosis in African Americans
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: BEHAVIORAL: Exercise Training effect on Hypertension and Gut Dysbiosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes
Status: COMPLETED
Conditions: Prediabetes|Type 2 Diabetes|Hypertriglyceridemia|Obesity|Disease|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Totum-63|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Three Techniques in Bioceramic Apexification for Necrotic Immature Incisors
Status: RECRUITING
Conditions: Immature Teeth|Periapical Lesion
Interventions: OTHER: Bioceramic Putty Apical Plugs|OTHER: Single Cone Gutta-percha with Bioceramic Sealer|OTHER: Combination of Bioceramic Putty and Sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Walter Reed Army Institute of Research (WRAIR) Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy US Adults
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: Live attenuated tetravalent dengue vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: A Study of Avonex to Determine the Effects of Dose Titration on the Incidence of Flu Like Symptoms in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Avonex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of an Integrative-kinesiological to a Cognitive-behavioural Intervention
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Cognitive Behavioural Training|BEHAVIORAL: Integrative Kinesiology Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Status: COMPLETED
Conditions: Rhytides|Wrinkle
Interventions: DEVICE: Venus Viva
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Imatinib and Nilotinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Imatinib|DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Doxycycline|DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Delafloxacin IV and OS Administration Compared to Best Available Therapy in Patients With Surgical Site Infections
Status: TERMINATED
Conditions: Surgical Site Infection
Interventions: DRUG: Delafloxacin|DRUG: Vancomycin|DRUG: Linezolid|DRUG: Piperacillin/Tazobactam|DRUG: Tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PMCF Study on the Safety and Performance of PROSPACE 3D / PROSPACE 3D OBLIQUE / TSPACE 3D
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Instability|Spondylolisthesis|Post-discectomy Syndrome|Post-traumatic Instabilities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Procalcitonin and Brain Natriuretic Peptides in Patients With Chronic Kidney Disease.
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DIAGNOSTIC_TEST: Brain Natriuretic Protein (BNP) and Procalcitonin (PCT) blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MR-HIFU for Bone Metastases
Status: COMPLETED
Conditions: Cancer|Bone Metastases
Interventions: DEVICE: Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR-HIFU)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NK Cell Immunotherapy on Advanced Lung Adenocarcinoma Adenocarcinoma With EGFR Mutation
Status: UNKNOWN
Conditions: NK Cell Mediated Immunity
Interventions: BIOLOGICAL: NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
Status: TERMINATED
Conditions: Spastic Cerebral Palsy
Interventions: DRUG: Extended-release Epidural morphine (EREM) 80|DRUG: Extended-release Epidural Morphine (EREM) 120|DRUG: Control: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FDG and FMISO PET Hypoxia Evaluation in Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Squamous Cell Carcinoma|Stage IB Cervical Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage IVA Cervical Cancer|Stage IVB Cervical Cancer
Interventions: OTHER: 18F-fluoromisonidazole|RADIATION: fluorodeoxyglucose F 18|PROCEDURE: positron emission tomography|OTHER: tissue oxygen measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BMS-986419|DRUG: Caffeine|DRUG: Bupropion|DRUG: Flurbiprofen|DRUG: Omeprazole|DRUG: Midazolam|DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Fluorescein in Fluorescence-guided Resection of Gliomas (FLEGME)
Status: COMPLETED
Conditions: Glioblastoma, Adult
Interventions: DRUG: Fluorescéine Sodique Faure|PROCEDURE: White-light surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Radiation Dose Prescription in HNSCC Based on F-MISO-PET Hypoxia-Imaging
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: RADIATION: dose-escalated radiochemotherapy|RADIATION: dose-escalated radiochemotherapy with carbon ion boost|RADIATION: standard radiochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing The Effectiveness Of Two Interventions To Reduce Vaccine Hesitancy Among Adolescents
Status: COMPLETED
Conditions: Vaccine Hesitancy|Vaccine Refusal|Health Knowledge, Attitudes, Practice
Interventions: BEHAVIORAL: Activité Vaccins et Vaccination - LAMAP|BEHAVIORAL: Kidivax Chatbot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Videoconferencing Versus Telephone Genetic Counseling
Status: COMPLETED
Conditions: Remote Consultation, Teleconsultation|Remote Consultation, Video
Interventions: OTHER: Videoconferencing Genetic Consultation|OTHER: Teleconferencing Genetic Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate an Updated Dexamethasone Intravitreal (Into the Eye) Applicator in Adult Participants With Macular Edema Due to Diseases of the Retina
Status: COMPLETED
Conditions: Macular Edema
Interventions: DEVICE: Updated DEX PS DDS Applicator|DEVICE: Approved DEX PS DDS Applicator|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Analysis of Time to Diagnosis and Length of Stay of Emergency Department Pelvic Ultrasonography
Status: COMPLETED
Conditions: Pregnancy
Interventions: OTHER: Emergency Medicine Physician Ultrasound|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 89Zr-J591 Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody in Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: 89Zr-J591|DEVICE: PET/CT Scan|DEVICE: MRI|OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Anemia
Interventions: DRUG: Biotin label
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Project Step: Evaluating Deposit Contracts and Daily Feedback to Promote Walking in Overweight and Obese Adults
Status: COMPLETED
Conditions: Physical Activity|Sedentary Lifestyle|Obesity|Overweight
Interventions: BEHAVIORAL: Self-monitoring|BEHAVIORAL: Incentives|BEHAVIORAL: Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Adjuvant Capecitabine After Resection of Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Weight Loss and Physical Activity Lifestyle Interventions In Post Liver And Kidney Transplants
Status: COMPLETED
Conditions: Weight Loss|Lifestyle Factors
Interventions: DEVICE: Wrist activity tracker and scale|BEHAVIORAL: Nutritional Coaching group sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Botulinum Toxin Type A to Treat Glabellar Lines
Status: COMPLETED
Conditions: Skin Aging
Interventions: DRUG: Botulinum Toxin Type A(Meditoxin®)|DRUG: Botulinum Toxin Type A(Botox®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Today Not Tomorrow Pregnancy and Infant Support Program (TNT- PISP)
Status: COMPLETED
Conditions: Infant Mortality|Infant Death|Racial Bias|Prenatal Stress|Prenatal Care|Maternal Child Health|Health Problems in Pregnancy|Adverse Childhood Experiences|Mental Health|Support Groups|Minority Health|Healthcare Disparities|Maternal-child Health Services|Social Determinants of Health|Trust|Physician-Patient Relations|Quality of Care
Interventions: OTHER: Today Not Tomorrrow Pregnancy and Infant Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Follow-Up Study of CARTISTEM® Versus Microfracture for the Treatment of Knee Articular Cartilage Injury or Defect
Status: COMPLETED
Conditions: Degenerative Osteoarthritis|Defect of Articular Cartilage
Interventions: BIOLOGICAL: CARTISTEM|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Immunogenicity of Intramuscular Sabin Inactivated Poliovirus Vaccine and Non-inferiority of Intradermal Fractional Inactivated Poliovirus Vaccine
Status: ACTIVE_NOT_RECRUITING
Conditions: Poliomyelitis
Interventions: BIOLOGICAL: Full dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS|BIOLOGICAL: Fractional (1/5) Dose Sabin Inactivated Poliovirus Vaccine produced by IMBCAMS|BIOLOGICAL: Full dose Sabin Inactivated Poliovirus Vaccine produced by BIBP|BIOLOGICAL: Fractional (1/5) dose Sabin Inactivated Poliovirus Vaccine produced by BIBP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
Status: WITHDRAWN
Conditions: Emergency Service, Hospital|Child/Adolescent Problem|Acute Pain|Fentanyl|Ibuprofen|Analgesics, Opioid|Anti-inflammatory Agents, Non-steroidal
Interventions: DRUG: INF2.0 + IBU|DRUG: INF1.0 + IBU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
Status: COMPLETED
Conditions: Craniofacial Microsomia|Hemifacial Microsomia|Oculo-Auriculo-Vertebral-Syndrome|Goldenhar Syndrome|Microtia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Cashew Apple Juice on the Physiological and Psychological Fitness in the Middle Aged and Elderly Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: placebo|OTHER: cashew apple juice|OTHER: cashew apple juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer.
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Advanced Cancer
Interventions: OTHER: Usual care|OTHER: Optimization of the medical decision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE