pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Physiotherapy After Botulinum Toxin Injection and Serial Casting
Status: COMPLETED
Conditions: Cerebral Palsy|Cerebral Palsy, Spastic
Interventions: PROCEDURE: backward downhill walking|PROCEDURE: routine physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Hepatectomy Versus Open Hepatectomy for PHC
Status: COMPLETED
Conditions: Primary Liver Carcinoma
Interventions: PROCEDURE: Open hepatectomy|PROCEDURE: Laparoscope hepatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
Status: COMPLETED
Conditions: Myopia|Refractive Error
Interventions: DRUG: ReNu MultiPlus® MultiPurpose Solution|DRUG: OPTI-FREE® RepleniSH®|DRUG: Clear Care®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Effectiveness of Telephone-based Early Childhood Developmental Screening
Status: COMPLETED
Conditions: Child Development|Developmental Disabilities|Ambulatory Care|Screening
Interventions: BEHAVIORAL: Telephone-based developmental screening and care coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Response Surface Pathway Design With Two Interventional- and One Response Variable in Estimating Minimum Efficacy Dose
Status: COMPLETED
Conditions: GERD
Interventions: PROCEDURE: Osteopatic Manual Therapy (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment
Status: NOT_YET_RECRUITING
Conditions: Syphilis Infection|Benzathine Penicillin Adverse Reaction
Interventions: DRUG: normal Saline|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Patients With Asymptomatic Carotid Artery Stenosis
Status: RECRUITING
Conditions: Carotid Artery Stenosis|Carotid Artery Stenosis Asymptomatic|Carotid Artery Diseases|Carotid Artery Plaque
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Cranberry Juice Consumption on Gut and Vaginal Microbiota in Post-menopausal Women
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Juice daily consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Methadone for Spinal Fusion Surgery.
Status: RECRUITING
Conditions: Pain, Postoperative|Back Pain|Opioid Use|Methadone|Degenerative Spondylolisthesis|Stenosis, Spinal
Interventions: DRUG: Methadone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of A Stigma Directed Interventional Program in Schizophrenia
Status: SUSPENDED
Conditions: Schizophrenia|Stigma, Social
Interventions: BEHAVIORAL: Stigma Directed Psycho-educational Intervention program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral-only Antibiotics for Bone and Joint Infections in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteomyelitis|Septic Arthritis|Bone Infection|Joint Infection|Bone and Joint Infection
Interventions: DRUG: Oral co-amoxiclav or oral dicloxacillin only|DRUG: IV ceftriaxon followed by oral co-amoxiclav or oral dicloxacillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Investigate the Effect of a Dysmenorrhoea App
Status: NOT_YET_RECRUITING
Conditions: Dysmenorrhea
Interventions: DEVICE: Pia-App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Prospective Study of Tai Chi Intervention to Delay the Progression of Subjective Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Subjective Cognitive Impairment
Interventions: BEHAVIORAL: Tai chi training|BEHAVIORAL: Group activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography
Status: COMPLETED
Conditions: Diabete Type 2|Unstable Angina|Myocardial Infarction|Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin 10Mg Tab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NutFish and Nutrient Supplementation in Pregnancy Class to Improve Maternal and Birth Outcomes
Status: UNKNOWN
Conditions: Pregnancy|Protein-Energy Malnutrition|Anemia
Interventions: OTHER: NutFish Based Food Supplementation|DIETARY_SUPPLEMENT: Multiple micronutrients|BEHAVIORAL: Health Education in Pregnancy Class|OTHER: Government Food Supplementation|DIETARY_SUPPLEMENT: Fe Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Varespladib Methyl (A-002)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPET in CF Patients With One G551D Mutation Taking VX770
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: DRUG: ivacaftor|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicentric Comparative Randomized Study of the Single-incision Sling Ajust® Versus Suburethral Transobturator Slings.
Status: COMPLETED
Conditions: Female Stress Urinary Incontinence
Interventions: DEVICE: Ajust sling|DEVICE: Classical transobturator sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: ferumoxytol|DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Post Approval Study of the Eversense® Continuous Glucose Monitoring
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: Eversense® CGM system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A New Anthrax Vaccine Administered by the Intramuscular (IM) Route in Healthy Adults
Status: COMPLETED
Conditions: Anthrax
Interventions: BIOLOGICAL: Anthrax|BIOLOGICAL: Alhdryogel or PBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Colchicine Use in Intracranial Atherosclerotic Disease
Status: RECRUITING
Conditions: ICAD - Intracranial Atherosclerotic Disease
Interventions: DRUG: Colchicine 0.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation During Pregnancy - One Versus Two Ferrous Sulfate Capsules for Iron Deficient Pregnant Women
Status: UNKNOWN
Conditions: Pregnancy Complications, Hematologic
Interventions: DRUG: two capsules of aktiferrin F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopurinol in Schizophrenia: A Randomized Trial Administering Allopurinol vs Placebo as add-on Antipsychotics in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Clinical Trial of Ex Vivo Corneal Cross-Linking of Donor Keratoplasty Tissue for Keratoconus Used for Keratoplasty in Keratoconus Patients
Status: NOT_YET_RECRUITING
Conditions: Keratoconus
Interventions: DRUG: Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% with UV light|DRUG: Riboflavin 5'-phosphate in 20% dextran ophthalmic solution) 0.146% without UV light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing SUV Accuracy of PET/MR for Clinical Trial Qualification
Status: COMPLETED
Conditions: Positron Emission Tomography-Magnetic Resonance (PET-MR)
Interventions: DIAGNOSTIC_TEST: Positron Emission Test / Magnetic Resonance (PET/MR)|DIAGNOSTIC_TEST: Positron Emission Test / Computed Tomography (PET/CT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: BIOLOGICAL: pegfilgrastim|DRUG: doxorubicin hydrochloride|DRUG: ifosfamide|DRUG: pegylated liposomal doxorubicin hydrochloride|PROCEDURE: conventional surgery|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users
Status: COMPLETED
Conditions: Insomnia Disorders
Interventions: DRUG: Zolpidem tablets|DRUG: Suvorexant tablets, over-encapsulated|DRUG: Lemborexant tablets|DRUG: Placebo lemborexant|DRUG: Placebo zolpidem|DRUG: Placebo suvorexant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Linaclotide Capsule in Bowel Preparation for Colonoscopy
Status: COMPLETED
Conditions: Bowel Preparation for Colonoscopy
Interventions: DRUG: 3L PEG + Linaclotide|DRUG: 3L PEG|DRUG: 2L PEG + Linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|BEHAVIORAL: Research Interview, Questionnaires|BEHAVIORAL: Brain Scan|BIOLOGICAL: Saliva Samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing Gene-Environment Interactions in Clinical Presentation of Nevi and Melanoma
Status: COMPLETED
Conditions: Nevi and Melanomas
Interventions: BEHAVIORAL: UV Counseling|OTHER: UV Photo|OTHER: Biological Sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single Ascending Oral Dose Study to Investigate the Effects of OCT461201 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: OCT461201 50 mg|DRUG: OCT461201 100 mg|DRUG: OCT461201 150 mg|DRUG: OCT461201 450 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients With Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: ARO-MMP7 Inhalation Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Exercise Effects in Individuals With Flatfoot
Status: COMPLETED
Conditions: Flat Foot [Pes Planus] (Acquired), Unspecified Foot
Interventions: OTHER: 3-dimensional foot-ankle extension exercises|OTHER: Clam exercise|OTHER: Short-foot exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy
Status: COMPLETED
Conditions: Parathyroid Adenoma|Parathyroid Neoplasms|Parathyroid Hyperplasia|Parathyroid Cancer|Hypercalcemia|Primary Hyperparathyroidism
Interventions: DEVICE: NIRAF Detection Technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Imaging for Response Assessment of Neoadjuvant Chemotherapy in Primary Breast Cancer (GALADON)
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Trastuzumab|DRUG: Bevacizumab|DRUG: Epirubicin|DRUG: Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BBT-877 in Healthy Subjects
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BBT-877, Single dose|DRUG: Placebo group|DRUG: BBT-877, Multiple doses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bednets and a Water Purification Device on HIV Disease Progression Among ART naïve Patients in Kenya
Status: COMPLETED
Conditions: HIV Infections|Human Immunodeficiency Virus|Malaria|Plasmodium Falciparum|Diarrhea
Interventions: OTHER: Bednets and Water Purification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Diseases|Kidney Transplant; Complications|COVID-19|Vaccine Adverse Reaction|Rejection Acute Renal|Rejection Chronic Renal
Interventions: BIOLOGICAL: Booster dose of mRNA vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Safety and Dosimetry Study in Patients With Confirmed Metastatic Melanoma
Status: TERMINATED
Conditions: Metastatic Melanoma
Interventions: DRUG: 131-I-MIP-1145
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endoscopic Ultrasound-guided Coil With Cyanoacrylate Injection Versus Balloon-Occluded Retrograde Transvenous Obliteration in Managing Patients With Gastric Varices
Status: NOT_YET_RECRUITING
Conditions: Gastric Varix
Interventions: PROCEDURE: Endoscopic ultrasound-guided coil embolization combined with endoscopic cyanoacrylate injection|PROCEDURE: Ballon-occluded retrograde transvenous obliteration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Food Effect on Pharmacokinetics of DA-8010 After a Single Administration of DA-8010 2.5 mg or 5 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DA-8010 2.5mg (Fasting)|DRUG: DA-8010 2.5mg (Fed)|DRUG: DA-8010 5mg (Fasting)|DRUG: DA-8010 5mg (Fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Knowledge and Self-confidence of Healthcare Workers to Perform Transurethral Catheterization: A Multicenter Survey
Status: UNKNOWN
Conditions: Urethral Catheterization|Urethral Catheterization Related Injury|Catheter Complications|Catheter Related Complication
Interventions: OTHER: Training Program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized, Double Blind Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986166 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-986166|DRUG: Placebo matching BMS-986166
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Investigate the Glucose Lowering Effects of Dextromethorphan Alone or in Combination With Sitagliptin in Subjects With Type 2 Diabetes Mellitus (T2DM) After an Oral Glucose Tolerance Test
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dextromethorphan|DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Clinical and Immune Response to Two Dengue Virus Vaccines in Healthy Adults
Status: COMPLETED
Conditions: Dengue
Interventions: BIOLOGICAL: rDEN1Δ30|BIOLOGICAL: Placebo|BIOLOGICAL: rDEN2Δ30-7169
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of an Ultraportable ECG Recording Device and Its Visualization Software for the Detection of Atrial Fibrillation
Status: UNKNOWN
Conditions: Cardiovascular Illnesses
Interventions: DEVICE: the use of the WitCard|OTHER: the use of WitDisplayer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Theory Construction and Effect of Intervention on Pregnant Women With Gestational Hypertension and Endocrine Disorders
Status: UNKNOWN
Conditions: Pregnancy-related Complications
Interventions: BEHAVIORAL: cognitive behaviors|BEHAVIORAL: Telephone consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Preoxygenation Method With a Calibrated Leak
Status: COMPLETED
Conditions: Preoxygenation|Non Invasive Ventilation
Interventions: PROCEDURE: preoxygenation without inward leak|PROCEDURE: preoxygenation with inward leak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity of PCV-7 Vaccine in VLBW Infants
Status: COMPLETED
Conditions: Pneumococcal Infections|Streptococcus Pneumoniae|Infant, Newborn|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Premature
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ET-02 in Patients With Relapsed or Refractory B-cell Malignancy(NHL/ALL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory B-cell Malignancy(NHL/ALL)
Interventions: BIOLOGICAL: ET-02
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin Versus Linagliptin in Renal Ransplant Recipients With Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus|Kidney Transplant; Complications
Interventions: DRUG: Empagliflozin 25 MG|DRUG: Linagliptin 5 mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facing Your Fears: Adolescents With ASD and Intellectual Disability
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Intellectual Disability|Anxiety|Emotion Regulation
Interventions: BEHAVIORAL: Facing Your Fears: ASD/ID|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Metastatic Colorectal Carcinoma|Metastatic Sarcoma|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography with Contrast|PROCEDURE: Microwave Ablation|OTHER: Questionnaire Administration|PROCEDURE: Wedge Excision
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CT-2103/Carboplatin vs Paclitaxel/Carboplatin for NSCLC in Women With Estradiol > 25 pg/mL
Status: WITHDRAWN
Conditions: NSCLC
Interventions: DRUG: CT-2103/carboplatin|DRUG: paclitaxel/carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yoga Breath Program and Client-Centered Exposure for Relief of PTSD in Tsunami Victims
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Breath Water Sound Course and Traumatic Incident Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind Phase II/III Trial of Monotherapy vs. Combination Therapy With Nucleoside Analogs in HIV-Infected Persons With CD4 Cells of 200-500/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: AMNIOX CORD Study - Radical Prostatectomy With and Without Cryopreserved Umbilical Cord Allograft
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Cryopreserved Umbilical Cord Allograft|PROCEDURE: Robot-Assisted Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Is the BAT Inhibition Able to Replace Sting Challenges? (BATIRS)
Status: RECRUITING
Conditions: Vespid Venom Allergy
Interventions: DIAGNOSTIC_TEST: sting challenge|OTHER: blood donation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Role for FGF21 in Postprandial Nutrient Homeostasis After RYGB
Status: RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Roux-en-Y gastric bypass surgery|BEHAVIORAL: Very low-calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Therapy of TCM Herbs to Improve the Success Rate of IVF-ET in Diminished Ovarian Reserve Patients
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: Er Zhi Wan combined with Si Wu Tang|DRUG: Recombinant Human Follitropin Alfa 、Fructose 、Tetyacycline Hydrochloride Capsules、Cetrorelix Acetate Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of LY353381 Vs Tamoxifen in Women With Locally Advanced or Metastatic Breast Cancer.
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: LY353381|DRUG: tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Instent Renarrowing With Aggressive Glucose Lowering With Pioglitazone in Diabetic Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Angina Pectoris|Type 2 Diabetes Mellitus|Percutaneous Coronary Intervention
Interventions: DRUG: pioglitazone|DRUG: oral hypoglycemic agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Spinal Or General Anesthesia For Umblical Hernia Surgery
Status: COMPLETED
Conditions: Umbilical Hernia|Spinal Aneshtesia|General Anesthesia
Interventions: OTHER: General Anesthesia|OTHER: Spinal Aneshtesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigating Barriers for Decision Making in a Danish Breast Cancer Screening Context
Status: COMPLETED
Conditions: Breast Cancer Female|Mammography Screening|Decision Making|Information Seeking Behavior
Interventions: OTHER: Stage of Decision Making|OTHER: Choice framing|OTHER: Opportunity Framing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Multiple-Dose Escalation and Single Dose (Tablet) Study of PF-04171327 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04171327|DRUG: Prednisolone|DRUG: Placebo|DRUG: Placebo Solution|DRUG: PF-04171327 Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating Safety and Tolerability of Inotuzumab Ozogamicin (CMC-544) in Japanese Patients With B-cell Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: Inotuzumab Ozogamicin (CMC-544)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CD123-Targeted CAR-T Therapy for Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Leukemia|Leukemia, Myeloid|Leukemia, Myeloid, Acute
Interventions: BIOLOGICAL: CD123 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Strength Training Versus Flexibility Training in Patients With Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: PROCEDURE: Strength training|PROCEDURE: Flexibility training|PROCEDURE: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SFA TReatment and vAscular Functions
Status: UNKNOWN
Conditions: Peripheral Arterial Disease|Claudication, Intermittent
Interventions: PROCEDURE: Angioplasty and drug coated balloon of the superficial femoral artery (SFA)|PROCEDURE: Angioplasty and stenting of the superficial femoral artery (SFA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Fecal Microbiome Transplantation (FMT) in the Treatment of Antibiotic Dependent Pouchitis (ADP)
Status: TERMINATED
Conditions: Pouchitis
Interventions: BIOLOGICAL: Active FMT, then open label FMT|BIOLOGICAL: Placebo FMT, then open label FMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled Trial Comparing the Use of a Biodegradable Temporizing Matrix to Cadaver Skin in the Reconstruction of Hidradenitis Suppurativa Excisions
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DEVICE: NovoSorb® BTM|DEVICE: Human Cadaveric Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of High-intensity Laser Therapy (HILT) in the Patients With Cervical Disc Herniation
Status: COMPLETED
Conditions: Cervical Disc Herniation
Interventions: DEVICE: High Intensity Laser Therapy|DEVICE: Ultrasound|DEVICE: Transcutaneous nerve stimulation (TENS)|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SPARC1103 in Subjects With Spasticity
Status: COMPLETED
Conditions: Spasticity
Interventions: DRUG: SPARC1103 low dose|DRUG: SPARC1103 high dose|DRUG: SPARC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain.
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen|DRUG: Placebo|DRUG: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: What Matters to Patients With Severe Hip or Knee Osteoarthritis?
Status: RECRUITING
Conditions: Hip Osteoarthritis|Knee Osteoarthritis
Interventions: BEHAVIORAL: Shared decision-making supported by an in-consultation PtDA to patients with severe osteoarthritis in their hip or knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Drug Eluting Beads TACE in Treatment of HCC in Egyptian Patients
Status: COMPLETED
Conditions: HepatoCellular Carcinoma
Interventions: DRUG: Trans-arterial chemoembolization (TACE)|DRUG: TACE with Drug Eluting Beads procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Hypoglossal Neurostimulation Study #2
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Sleep Apnea, Obstructive|Respiration Disorders|Signs and Symptoms, Respiratory|Syndrome, Obstructive Sleep Apnea
Interventions: DEVICE: aura6000 THN System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Behavioral Approaches With Functional Electrical Therapy in Stroke Rehabilitation
Status: WITHDRAWN
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: dCIT|BEHAVIORAL: BAT|BEHAVIORAL: Control intervention group|BEHAVIORAL: Functional electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mini Trampoline Exercise Program on Diabetic Foot Care Behavior and Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetic Foot|Type 2 Diabetes
Interventions: OTHER: Mini trampoline exercise group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CONDOL01: Evaluation on the Experience of Bereavement, of a Medical Consultation, Proposed by a Letter of CONDOLence to the Patients' Relatives Versus Standard Practice After the Death of the Patient
Status: UNKNOWN
Conditions: Caregivers
Interventions: BEHAVIORAL: Letter of condolence and post-death medical consultation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PFDD Versus PFDRT in Chiari Decompression Surgery
Status: RECRUITING
Conditions: Chiari Malformation Type I|Tonsillectomy
Interventions: PROCEDURE: Posterior fossa decompression with duraplasty|PROCEDURE: PFDD with tonsillar resection/reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A More Engaging Visual Field Test to Increase Use and Reliability in Pediatrics
Status: RECRUITING
Conditions: Glaucoma, Suspect|Optic Nerve Hypoplasia and Abnormalities of the Central Nervous System|Congenital Coloboma of the Optic Nerve|Optic Nerve Head Pits, Bilateral Congenital
Interventions: DEVICE: Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry|OTHER: Usual Care procedures during Humphrey perimetry for children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dichloroacetate (DCA) in Patients With Previously Treated Metastatic Breast or Non-Small Cell Lung Cancer (NSCL)
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Lung Cancer
Interventions: DRUG: Dichloroacetate (DCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Neoral Monotherapy Compared to Bitherapy in Renal Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Cyclosporin A: C0: 75-125ng/ml-dose adapted in the 3 groups|DRUG: Group A: CsA + Azathioprine(1 to 2 mg/kg/day)|DRUG: Group B: CsA + CellCept(500 mg x 2/day)|DRUG: Group C: CsAm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semaglutide in Auto-HSCT
Status: NOT_YET_RECRUITING
Conditions: Intestinal Mucositis|Inflammation|Chemotherapeutic Toxicity
Interventions: DRUG: Semaglutide Pen Injector [Ozempic]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Lebrikizumab Treatment in Adults and Adolescents With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis|Eczema
Interventions: BIOLOGICAL: Lebrikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Prasugrel and Clopidogrel in Low Body Weight Versus Higher Body Weight With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: prasugrel|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blind Trial of the Quadrivalent HPV Vaccine to Improve Responses to LEEP Treatment of Cervical HSIL
Status: COMPLETED
Conditions: Cervical High Grade Squamous Intraepithelial Lesion
Interventions: BIOLOGICAL: Human Papillomavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of CKD-501 Added to D150 Plus D745 10mg Therapy in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes
Interventions: DRUG: CKD-501 0.5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Satisfaction of Blood Glucose Management Between Continuous Glucose Monitoring Versus Traditional Self-blood Glucose Measurement in Diabetic Patients After Pancreatectomy
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DEVICE: Dexcom G6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Deaf Weight Wise 2.0: A Healthy Lifestyle Intervention With Deaf Adults Who Are Overweight or Obese
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Deaf Weight Wise 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability, and Pharmacodynamic Effects of GLY-200 in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: GLY-200|DRUG: GLY-200|DRUG: GLY-200|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Duvelisib in Combination With Either Romidepsin or Bortezomib in Relapsed/Refractory T-cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|Relapsed/Refractory T-cell Lymphomas
Interventions: DRUG: Romidepsin|DRUG: Bortezomib|DRUG: duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise For Fighting Oncology Repercussions After Treatment
Status: NOT_YET_RECRUITING
Conditions: Neoplasms
Interventions: BEHAVIORAL: Nordic Walking|BEHAVIORAL: Aquatic Exercise|BEHAVIORAL: Functional Exercise Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders
Status: RECRUITING
Conditions: Dementia|Alzheimer Disease|Epilepsy|Sleep Disorder|Circadian Rhythm Disorders|Healthy
Interventions: DIAGNOSTIC_TEST: EEG,PSG|DIAGNOSTIC_TEST: biosample collection (blood and CSF)|DIAGNOSTIC_TEST: neuropsychological testing|DIAGNOSTIC_TEST: actigraphy|DIAGNOSTIC_TEST: clinician assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurological Complication of Infective Endocarditis: A Prospective Multi-site Cohort Study
Status: UNKNOWN
Conditions: Endocarditis, Bacterial|Aneurysm, Intracranial Mycotic
Interventions: DIAGNOSTIC_TEST: Brain MRI|DIAGNOSTIC_TEST: digital subtraction angiography (DSA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034)
Status: COMPLETED
Conditions: Solid Tumors|Non-small Cell Lung Cancer|Castration Resistant Prostate Cancer|Microsatellite Stable Colorectal Cancer
Interventions: DRUG: Navarixin|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Feasibility Study Of Pressure-controlled Intermittent Coronary Sinus Occlusion (PICSO) In Patients With Coronary Artery Disease Undergoing Native Vessel Intervention
Status: COMPLETED
Conditions: Stable Angina
Interventions: PROCEDURE: PICSO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 and Therapy Study for Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Omega-3 Supplementation|BEHAVIORAL: Psychoeducational Psychotherapy (PEP)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bronchiolitis Follow-up Intervention Trial
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: BEHAVIORAL: Scheduled PCP follow-up|BEHAVIORAL: As needed PCP follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects on Physical Activity on Mitochondrial Function in Skin Fibroblasts in Patients With Parkinson's Disease.
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: Physical activity|OTHER: usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of an Alternative Treatment Approach (Preoperative Radiotherapy, Then Mastectomy, Then Immediate Reconstruction Surgery) in People With T4 Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Invasive Breast Cancer
Interventions: DIAGNOSTIC_TEST: Pre-neoadjuvant radiotherapy (NART) biopsy|RADIATION: Neoadjuvant radiotherapy|PROCEDURE: Unilateral total mastectomy with axillary lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lubiprostone on Gastric Function in Patients With Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Chronic Idiopathic Constipation
Interventions: DRUG: lubiprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas
Status: COMPLETED
Conditions: Alveolar Soft Part Sarcoma|Soft Tissue Sarcomas
Interventions: DRUG: Axitinib|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Norepinephrine Versus Ephedrin for Prevention of Post Spinal Anesthesia in Cesarean Section
Status: UNKNOWN
Conditions: Maternal Hypotension Syndrome|Cesarean
Interventions: DRUG: Ephedrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect and Tolerance of Botulinum A Toxin Rectal Injections on Fecal Incontinence
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: PROCEDURE: Rectoscopy|PROCEDURE: Anorectal manometry|DRUG: Botulinum toxin A or physiologic serum injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect on Body Weight of Leptin Administered in Conjunction With Pramlintide in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: pramlintide acetate 360 mcg|DRUG: metreleptin|DRUG: placebo-pramlintide 600 uL|DRUG: placebo-metreleptin 1 mL|DRUG: Pramlintide acetate 180 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camrelizumab Combined With Apatinib for Advanced Gastric or Esophagogastric Adenocarcinoma
Status: UNKNOWN
Conditions: Advanced Gastric Carcinoma
Interventions: DRUG: camrelizumab|DRUG: Apatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippotherapy to Improve the Balance of Children With Movement Disorders
Status: COMPLETED
Conditions: Neuromuscular Diseases|Cerebral Palsy|Down Syndrome|Autism|Developmental Coordination Disorder
Interventions: OTHER: Hippotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sertraline Hydrochloride Tablets 100 mg and Zoloft® Tablets 100 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sertraline Hydrochloride Tablets 100 mg|DRUG: Zoloft® Tablets 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN)
Status: TERMINATED
Conditions: Diabetic Macular Edema|Branch Retinal Vein Occlusion|Glaucoma/Closed Angle Glaucoma
Interventions: DRUG: IRX-101|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genes
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer|Metastatic Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT