pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Venous Thromboembolism|Thromboembolism|Thrombosis|Embolism and Thrombosis|Deep Vein Thrombosis|Arthroplasty, Replacement, Hip
Interventions: DRUG: DU-176b 15mg|DRUG: DU-176b 30mg|DRUG: Enoxaparin sodium 20 mg (=2000IU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled, 3x3 Factorial Design, Phase II Study to Evaluate the Antihypertensive Efficacy and Safety of Combination of Fimasartan and Amlodipine in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan , Amlodipine, Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Operative Course in Connection With Removal of Lower Third Molars
Status: COMPLETED
Conditions: Postoperative Pain|Inflammation
Interventions: DRUG: methylprednisolone|DRUG: placebo|DRUG: xyloplyin adrenalin|DRUG: marcain adrenalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Magnesium Lactate in the Reduction of Gestational Diabetes Incidence.
Status: WITHDRAWN
Conditions: Pregnancy Related
Interventions: DIETARY_SUPPLEMENT: Magnesium lactate.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study Evaluation of the Efficacy of SonoVue to Detect and Characterise Breast Lesions
Status: COMPLETED
Conditions: Breast Tumors
Interventions: DRUG: SonoVue (sulphur hexafluoride microbubbles)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment
Status: COMPLETED
Conditions: Postmenopausal Women With Advanced Breast Cancer
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala Activity-Based Breastfeeding Program on Breastfeeding Self-Efficacy and Maternal-Infant Attachment of Primiparous Mothers
Status: COMPLETED
Conditions: Breastfeeding|ART|Self Efficacy|Maternal-Fetal Relations
Interventions: OTHER: "Mandala Activity-Based Breastfeeding Program"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Sintilimab+Bevacizumab+TACE vs. Lenvatinib+TACE for Advanced HCC
Status: RECRUITING
Conditions: Hepatocellular Carcinoma Non-resectable
Interventions: DRUG: Sin-Bev-TACE|DRUG: Len-TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NVA237 BID Versus Placebo Twelve-week Efficacy Study
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: NVA237|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Companion Sample Collection Protocol to Support the Discovery of Breast Cancer Aberrations With Treatment of CDK4/6 Therapy/LEE011/Ribociclib
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Disseminating a Dashboard for VA Purchased Community Nursing Homes
Status: UNKNOWN
Conditions: Nursing Home|Veterans|Functional Impairment|Quality of Care
Interventions: OTHER: Access to the CNH Dashboard Step 1|OTHER: Access to the CNH Dashboard Step 2|OTHER: Access to the CNH Dashboard Step 3|OTHER: Access to the CNH Dashboard Step 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: QLB vs ESPB for Lumbar Spinal Surgery
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: OTHER: QLB|OTHER: ESPB|OTHER: Postoperative analgesia management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of hiHep Bioartificial Liver Support System to Treat Acute Liver Failure
Status: UNKNOWN
Conditions: Liver Failure, Acute
Interventions: PROCEDURE: hiHep Bioartificial Liver Support System|PROCEDURE: Standard care for ALF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Status: WITHDRAWN
Conditions: Type 1 Diabetes
Interventions: OTHER: 6-day intervention with sensor-augmented pump therapy|OTHER: 6-day intervention with single-hormone closed-loop strategy|OTHER: 6-day intervention with dual-hormone closed-loop strategy|DRUG: Insulin|DRUG: Glucagon|DEVICE: Continuous Glucose Monitoring System Enlite sensor®, Medtronic|DEVICE: Insulin pump MiniMed® Paradigm® Veo™, Medtronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bleeding Pattern and User Satisfaction During Second Consecutive MIRENA® in Contraception and Treatment of Menorrhagia
Status: COMPLETED
Conditions: Contraception|Menorrhagia
Interventions: DRUG: Levonorgestrel (Mirena, BAY86-5028)|DRUG: Cytotec|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of HBM-Based Education on Nursing Students
Status: NOT_YET_RECRUITING
Conditions: Nursing|Evidence-Based Nursing
Interventions: BEHAVIORAL: Experiment group|OTHER: Pre-post test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Diet and Exercise in Type 2 Diabetes - a Randomized Controlled Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Modified paleolithic diet and exercise under observation|BEHAVIORAL: Modified paleolithic diet and general advice on exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting and Assessing Leg and Foot Stress Fractures Using Photon Counting CT
Status: RECRUITING
Conditions: Stress Fracture Foot|Stress Fracture Ankle|Stress Fracture of Tibia|Stress Fracture Metatarsal|Lower Limb Fracture
Interventions: DIAGNOSTIC_TEST: Photon-Counting-Computed-Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: This Study Aims to Find a Safe and Effective Dose of BI 754091. The Study Also Aims to Find Safe and Effective Doses of BI 754091 and BI 754111 in Combination. This Study is Done in Asian Patients With Different Types of Cancer
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BI 754091|DRUG: BI 754111
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Substitution With Ferric Carboxymaltose as Treatment Strategy for Heart Failure Patients With Preserved Ejection Fraction
Status: WITHDRAWN
Conditions: Heart Failure With Normal Ejection Fraction|Iron-deficiency
Interventions: DRUG: Ferric carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrostimulation System WoundEL for Leg Ulcers Healing (
Status: RECRUITING
Conditions: Leg Ulcer|Electrical Remodeling
Interventions: DEVICE: WoundEL medical device|OTHER: Standard cares
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo and Moxifloxacin Controlled Cardiac Conduction Study of GSK2140944 in Healthy Volunteers
Status: COMPLETED
Conditions: Infections, Respiratory Tract
Interventions: DRUG: GSK2140944|DRUG: GSK2140944 placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Procellera® Compared to Standard of Care Treatment in Mitigating Biofilm Formation in Acute Trauma and Burn Wounds
Status: COMPLETED
Conditions: Trauma-related Wound|Burn, Partial Thickness
Interventions: DEVICE: Procellera®|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Usefulness of Endoscopic Ultrasound-guided Biliary Drainage With a Newly Designed Hybrid Metallic Stent
Status: COMPLETED
Conditions: Bile Duct Obstruction|Disorder of Bile Duct Stent|Neoplasms
Interventions: DEVICE: EUS-guided biliary drainage with a hybrid metallic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis (MF)
Interventions: DRUG: Navitoclax|DRUG: Ruxolitinib|DRUG: Placebo for Navitoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Task of Acoustic-phonetic Decoding on Anatomic Deficits in Paramedical Assessment of Speech Disorders for Patients Treated for Oral or Oropharyngeal Cancer
Status: RECRUITING
Conditions: Speech Intelligibility
Interventions: OTHER: Acoustic-phonetic decoding task (DAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NAPAGE: NAb-PAclitaxel and GEmcitabine in Advanced Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Nab-Paclitaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Registry Study on the Implementation of Simultaneous Postoperative Radiochemotherapy for Salivary Gland Carcinomas of the Head and Neck Region
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Salivary Gland Carcinoma
Interventions: PROCEDURE: simultaneous postoperative radiochemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Genital Psoriasis
Status: COMPLETED
Conditions: Genital Psoriasis|Psoriasis
Interventions: DRUG: Ixekizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Liver Health Study for Patients With NAFLD
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver|Nonalcoholic Steatohepatitis|Obesity
Interventions: BEHAVIORAL: Phase II: Lifestyle treatment|BEHAVIORAL: Phase II: Control treatment|OTHER: Phase I: Observational studies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Assess Change in Disease Activity and Adverse Events of Ab Externo Approach for Glaucoma Gel Stent (XEN45) Implantation In Participants Aged 45 Years or Older With Open-Angle Glaucoma
Status: RECRUITING
Conditions: Open-Angle Glaucoma
Interventions: DEVICE: XEN45 (Glaucoma Gel Stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Vaginal Self Sampling for Human Papillomavirus (HPV)
Status: UNKNOWN
Conditions: Human Papillomavirus Infection|Cervical Intraepithelial Neoplasia
Interventions: DEVICE: offer of vaginal self collection|OTHER: 2nd reminder letter for Pap testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Nebulized RNS60 to Treat Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: RNS60|DRUG: RNS60 - single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Lifestyles for Children With Complex Heart Problems
Status: COMPLETED
Conditions: Congenital Heart Defects|Inherited Cardiac Arrhythmias|Cardiomyopathy
Interventions: BEHAVIORAL: Supplementary resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Proximal and Distal Approach GON RFT in Migraine
Status: ACTIVE_NOT_RECRUITING
Conditions: Migraine Disorders|Headache Migraine Chronic
Interventions: PROCEDURE: Greater occipital nerve radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BTRX-246040 Administered Once Daily to Patients With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: BTRX-246040 oral capsule(s)|DRUG: Placebo oral capsule(s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-12 Gene in Treating Patients With Liver Metastases Secondary to Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: BIOLOGICAL: adenovirus vector|BIOLOGICAL: interleukin-12 gene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Paclitaxel With or Without Trastuzumab in Stage I-II Breast Cancer Who Have Undergone Surgery
Status: COMPLETED
Conditions: Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: paclitaxel|BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Memantine in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Ginseng Polysaccharide Extract
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Y-75|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety, Efficacy Study of CombiflexOmega Peri Versus SmofKabiven Peripheral in Patients With Parenteral Nutrition
Status: COMPLETED
Conditions: Parent
Interventions: DRUG: CombiflexOmega peri|DRUG: SmofKabiven peripheral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AuraGainTM and I-Gel® Laryngeal Masks in General Anesthesia for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Respiratory Aspiration of Gastric Content
Interventions: DEVICE: I-gel LMA insertion|DEVICE: AuraGain LMA insertion|DEVICE: ETT insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Childhood Malignant Fibrous Histiocytoma of Bone|Sarcoma
Interventions: BIOLOGICAL: dactinomycin|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Organ-Preserving Endoscopic Resection & Adjuvant RADIO-immuno-chemotherapy for Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Adjuvant Immunoradiotherapy (ARM1) and Adjuvant Immunotherapy (ARM1B)|DRUG: Adjuvant chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety 6-months Study of SYNOLIS VA 80/160 and SYNOLIS VA 40/80 in the Treatment of Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: SYNOLIS VA 80/160|DEVICE: SYNOLIS VA 40/80
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ISAR-DAPT (A Comparative Evaluation of Efficacy and Safety in the 3-Months DAPT Group vs. the 6-Months DAPT Group of Patients Treated With the Coroflex ISAR Stent; A Prospective, Multicenter, Randomized, Open-Label Clinical Trial)
Status: UNKNOWN
Conditions: Stable Angina, Unstable Angina, Silent Coronary Ischemia, Coronary Artery Disease
Interventions: DEVICE: Coroflex ISAR|DRUG: 3 months DAPT|DRUG: 6 months DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods
Status: COMPLETED
Conditions: N/A, as no Specific Medical Condition Will be Treated
Interventions: DRUG: IncobotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Complications in Cancer Patients Monitored With Intelligent Continuous Monitoring System
Status: RECRUITING
Conditions: Postoperative Complications|Cancer, Treatment-Related
Interventions: DEVICE: WARD-CSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TRANEXAMIC ACID IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY IN A BRAZILIAN REFERENCE ORTHOPEDIC CENTER: A RANDOMIZED CONTROLLED TRIAL
Status: COMPLETED
Conditions: Blood Loss, Surgical|Tranexamic Acid Adverse Reaction|Hip Replacement
Interventions: DRUG: Tranexamic Acid Injectable Solution|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: DECREASE: Dapagliflozin Plus Exenatide on Central REgulation of Appetite in diabeteS typE 2
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: DRUG: Dapagliflozin 10mg|DRUG: Exenatide|OTHER: placebo exenatide|OTHER: placebo dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Psychosocial Education Programme for Young People With Type 1 Diabetes - the Youth Empowerment Skills (YES)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Youth Empowerment Skills|BEHAVIORAL: Waiting-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety/Efficacy Study of Rexin-G to Treat Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: GENETIC: Rexin-G|GENETIC: Rexin-G|GENETIC: Rexin-G|GENETIC: Rexin-G|GENETIC: Rexin-G
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of AFL-assisted PDT With Short Incubation Time in Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 2h-AFL-PDT|DRUG: 3h-AFL-PDT|DRUG: 3hr-MAL-PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: SABER-Bupivacaine Treatment 1a|DRUG: Placebo SABER-Bupivacaine Treatment 1b|DRUG: Bupivacaine HCl Treatment 1c|DRUG: SABER-Bupivacaine Treatment 2a|DRUG: Placebo SABER-Bupivacaine Treatment 2b|DRUG: Bupivacaine HCl Treatment 2c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus
Status: TERMINATED
Conditions: Hepatitis B|HBV|Hepatitis B, Chronic
Interventions: DRUG: Inarigivir soproxil|DRUG: Tenofovir alafenamide fumarate (TAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Effect of Transcutaneous Stimulation of the Vagus Nerve on Pain Perception and Parameters of the Autonomic Nervous System
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Cerbomed t-VNS® transcutaneous stimulation|DEVICE: t-VNS Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of KRN23 in Subjects With Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome
Status: COMPLETED
Conditions: Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome
Interventions: DRUG: KRN23
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZD1839 (Iressa™) and Concurrent Chemo-Radiation in Patients With Locally Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Carcinoma
Interventions: DRUG: Gefitinib|DRUG: Carboplatin|DRUG: Paclitaxel|PROCEDURE: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Imiquimod|DRUG: Zyclara®|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Respiratory Variations of the Right Internal Jugular Vein as a Predictor of Fluid Responsiveness During Mechanical Ventilation
Status: UNKNOWN
Conditions: Jugular Veins|Ultrasonography
Interventions: DIAGNOSTIC_TEST: respiratory variation of the right internal jugular vein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Investigate the Use of Acalabrutinib in the Treatment of Patients With Chronic Lymphocytic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia- Binet Staging System
Interventions: DRUG: Acalabrutinib 100 MG Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Using NaviFUS System in Patients With Drug Resistant Epilepsy
Status: COMPLETED
Conditions: Drug Resistant Epilepsy|Epilepsy, Drug Resistant|Drug Refractory Epilepsy|Epilepsy, Drug Refractory|Intractable Epilepsy|Epilepsy, Intractable|Medication Resistant Epilepsy|Refractory Epilepsy
Interventions: DEVICE: NaviFUS System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of Sequential Chemotherapy With Antimetabolite Induction, High-Dose Alkylating Agent Consolidation With Peripheral Blood Progenitor Cell Support, and Intensification With Paclitaxel and Doxorubicin for Patients With High-Risk Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: methotrexate|DRUG: leucovorin|DRUG: 5-fluorouracil|DRUG: cyclophosphamide|PROCEDURE: peripheral blood progenitor cell|DRUG: paclitaxel|DRUG: doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Gutta-percha Solvent on Postoperative Pain After Root Canal Retreatment
Status: COMPLETED
Conditions: Postoperative Pain|Root Canal|Retreatment
Interventions: PROCEDURE: solvent|PROCEDURE: non-solvent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Increase Study. Effect of Incremental Versus Fixed Pump on Peak Oxygen Consumption in Heart Failure Patients Supported With a Continuous Flow Left Venticular Assist Device
Status: COMPLETED
Conditions: Heart Failure.
Interventions: DEVICE: Incremental pump speed of CF-LVAD.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Intravenous Fluids in Pediatric Migraine
Status: RECRUITING
Conditions: Migraine|Migraine in Children
Interventions: OTHER: 1/2 maintenance fluids|DRUG: Ketorolac|DRUG: Diphenhydramine|DRUG: Prochlorperazine|OTHER: bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Multicenter Study to Evaluate the Safety and Efficacy of the ReShape Duo™ Intragastric Balloon System in Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: ReShape Duo balloon|OTHER: Diet counseling|OTHER: Exercise counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Overweight|Obesity|Stress, Physiological|Stress, Psychological
Interventions: BEHAVIORAL: Stress reduction|BEHAVIORAL: Stress reduction with Health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parameters of 2 Phaco Tips Designs in Torsional Phacoemulsification
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Mini-flared|DEVICE: Reversed tip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upper- and Lower-body Resistance Exercise With and Without Blood Flow Restriction on Hemodynamics and Vascular Function
Status: UNKNOWN
Conditions: Endothelial Dysfunction|Autonomic Dysfunction
Interventions: OTHER: Resistance Exercise with Blood Flow Restriction|OTHER: High-intensity Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Administration of Arginine Supplementation in Preterm Infants
Status: UNKNOWN
Conditions: Necrotizing Enterocolitis
Interventions: DIETARY_SUPPLEMENT: arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Silymarin for the Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: Sillymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auranofin in Decreasing Pain in Patients With Paclitaxel-Induced Pain Syndrome
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: auranofin|OTHER: placebo|OTHER: questionnaire administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy and Safety Study of Fentanyl Transdermal Patch in Filipino Participants With Osteoarthritis and Chronic Low Back Pain
Status: COMPLETED
Conditions: Osteoarthritis|Low Back Pain
Interventions: DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Up-regulating Positive Affect in Emotional Disorders
Status: COMPLETED
Conditions: Anxiety|Depression
Interventions: BEHAVIORAL: Transdiagnostic treatment protocol|BEHAVIORAL: Transdiagnostic treatment protocol + PA regulation component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rollover Study in Participants With Metastatic Solid Tumors Benefiting From Therapy With Sacituzumab Govitecan-hziy
Status: ENROLLING_BY_INVITATION
Conditions: Metastatic Solid Tumor
Interventions: DRUG: Sacituzumab Govitecan-hiy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of LEO 80185 Gel on the HPA Axis and Calcium Metabolism in Subjects With Extensive Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 80185 (Xamiol® gel/Taclonex® Scalp topical suspension)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy Combined With PD-1 Inhibitor Sequential GM-CSF and IL-2 for the Treatment of Advanced Refractory Solid Tumors (PRaG2.0)
Status: UNKNOWN
Conditions: Advanced Refractory Solid Tumors
Interventions: RADIATION: Hypofractionated radiotherapy|DRUG: PD-1 inhibitor|DRUG: GM-CSF|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery
Status: UNKNOWN
Conditions: Infection|Pneumonia|Surgical Site Infection|Wound Infection|Surgical Wound Infection|Postoperative Complications|Anesthesia|Communicable Disease|Pathologic Processes|Perioperative Complication|Chlorhexidine|Laparotomy
Interventions: DRUG: Chlorhexidine mouthwash|DRUG: Oxygen|DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Retrograde Autologous Priming on Transfusion Requirements After Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Red Blood Cell Transfusion
Interventions: PROCEDURE: retrograde autologous priming (RAP)|PROCEDURE: Crystalloid priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Investigational Drug Study to Lower Non-Cholesterol Sterol Levels Associated With Sitosterolemia (0653-062)(COMPLETED)
Status: COMPLETED
Conditions: Lipid Metabolism, Inborn Errors|Heart Disease
Interventions: DRUG: MK0653, ezetimibe|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Glycemic Index Diets vs. High Cereal Fibre Diets in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes|Cardiovascular Disease
Interventions: OTHER: Low Glycemic Index diet|OTHER: High Cereal Fibre Diets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coronary Computed Tomographic Angiography for Selective Cardiac Catheterization
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Cardiac CT|PROCEDURE: Invasive Coronary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Rapamycin for Fibrofolliculomas
Status: COMPLETED
Conditions: Birt-Hogg-Dubé Syndrome
Interventions: DRUG: Rapamycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of an Exoskeleten With an End-effector for Assisted Gait Training in Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: OTHER: robot assisted gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AXR-270 for the Treatment of Posterior Blepharitis Associated With Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Posterior Blepharitis|Meibomian Gland Dysfunction
Interventions: DRUG: AXR-270 Low Dose|DRUG: AXR-270 High Dose|DRUG: AXR-270 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an 8-week Heartfulness Meditation Program on Burnout and Stress at Veterinary Specialty Hospital
Status: COMPLETED
Conditions: Stress|Burnout, Professional
Interventions: BEHAVIORAL: 8-week wellness and relaxation meditation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BBI503 in Advanced Solid Tumors, or BBI503/ Sorafenib in Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Advanced Solid Tumors|Hepatocellular Carcinoma
Interventions: DRUG: BBI503|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Intra-abdominal t-PA and DNase on Peritonitis in Peritoneal Dialysis Patients
Status: TERMINATED
Conditions: Peritoneal Dialysis|Peritoneal Dialysis, Continuous Ambulatory
Interventions: DRUG: Tissue Plasminogen Activator (tPA)|DRUG: recombinant deoxyribonuclease (DNase)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Nimodipine Concentrations Following Oral, Intra-venous and Intra-arterial Administration
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Delayed Cerebral Ischemia|Vasospasm, Cerebral
Interventions: DRUG: Nimodipine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery
Status: COMPLETED
Conditions: Stroke|Chronic Stroke|Walking, Difficulty|Gait, Hemiplegic
Interventions: BEHAVIORAL: Backward Locomotion Treadmill Training (BLTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Glycogen Liver Content Will Improve Post-operative Liver Function in Patients Undergoing Major Liver Resections
Status: COMPLETED
Conditions: Liver Function
Interventions: DRUG: dextrose 10% (D10W ®) infusion|DRUG: hyperinsulinemic normoglycemic clamp|DIETARY_SUPPLEMENT: high calorie diet 35 kcal/kg|DRUG: Intravenous normal saline (NS 0.9)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Potassium on Glucose Metabolism in African Americans
Status: COMPLETED
Conditions: Borderline Hypokalemia
Interventions: DRUG: K+ supplement|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Controlled-release Oxycodone on Postoperative Pain in Oncologic Head and Neck Surgery
Status: COMPLETED
Conditions: Postoperative Nausea|Adverse Effects|Opioid Analgesic Adverse Reaction|Pain
Interventions: DRUG: Controlled-release oxycodone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intraoperative Music Application and Postoperative Behaviour in Children and Adolescents.
Status: COMPLETED
Conditions: Postoperative Behaviour
Interventions: OTHER: music application|OTHER: only headphones|DRUG: a caudal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma
Status: COMPLETED
Conditions: Metastatic Osteosarcoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cisplatin|DRUG: methotrexate|DRUG: leucovorin calcium|BIOLOGICAL: filgrastim|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy|DRUG: etoposide|DRUG: ifosfamide|BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Prospective Trial Comparing Contact Force and Non-contact Force Guided Catheter Ablation for Cavotricuspid Isthmus Dependent Atrial Flutter
Status: UNKNOWN
Conditions: Atrial Flutter|Radiofrequency Catheter Ablation
Interventions: DEVICE: Contact force guided RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Topical Nepafenac to Placebo in Corneal Epithelial Healing Times and Postoperative Pain Relief
Status: COMPLETED
Conditions: Photorefractive Keratectomy
Interventions: DRUG: nepafenac 0.1%|OTHER: ketorolac 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sodium Valproate in Patients With Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Sodium valproate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: IV acetaminophen|DRUG: IV placebo|DRUG: hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Speech Fluency With Non-invasive Brain Stimulation in Developmental Stuttering
Status: COMPLETED
Conditions: Stuttering|Fluency Disorders|Speech Disorders
Interventions: DEVICE: Anodal TDCS|BEHAVIORAL: Fluency Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients
Status: UNKNOWN
Conditions: Pulmonary Veno-Occlusive Disease|Hepatic Veno-Occlusive Disease|Mucositis
Interventions: DRUG: Glutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Urine HPV Testing for Cervical Cancer Screening Among Women Living With HIV in South Africa
Status: RECRUITING
Conditions: Cervical Cancer|CIN2|CIN3
Interventions: OTHER: Urine HPV testing|OTHER: Self-collected cervicovaginal specimen|OTHER: Provider-collected cervical samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized Controlled Study of the Effectiveness of Scalp Electroacupuncture in Improving Upper Limb Motor Function in Convalescent Phase of Ischemic Stroke.
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DEVICE: scalp electroacupuncture|DEVICE: sham scalp electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Single-Dose Liposomal Bupivacaine in Surgeon Performed Intercostal Nerve Blocks
Status: COMPLETED
Conditions: Thoracic
Interventions: DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Impaired Glucose Tolerance (IGT)|Impaired Fasting Glucose (IFG)
Interventions: DRUG: Dapagliflozin|DRUG: Saxagliptin|DRUG: Pioglitazone|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-concept Study of VCH-759 for the Treatment of Hepatitis C-infection.
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: VCH-759 (BCH-27759)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Diclofenac HPBCD 75mg/ml in Treatment of Pain Following Dental Surgery
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Diclofenac HPBCD s.c. 75mg/ml|DRUG: Voltarol 75mg/3ml i.m.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Speech and Swallowing Assessment in ALS
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DEVICE: Digital recording of speech and swallow sounds using the Beiwe Digital Health App on a personal smartphone|RADIATION: Modified Barium Swallow Study (MBSS)|BEHAVIORAL: Speech Intelligibility Test (SIT)|BEHAVIORAL: SIT Scoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paroxetine vs Placebo Combined With Aerobic Exercise or Relaxation in Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: DRUG: paroxetine + aerobic exercise|DRUG: Paroxetine + relaxation|DRUG: Placebo + aerobic exercise|DRUG: Placebo + relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: BIOLOGICAL: REMD-477|BIOLOGICAL: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Buccal Film Versus IV Injection Palonosetron for Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting
Status: COMPLETED
Conditions: Nausea With Vomiting Chemotherapy-Induced
Interventions: DRUG: Palonosetron Hydrochloride Buccal Film 0.25 Mg|DRUG: Palonosetron Hydrochloride Buccal Film 0.5 Mg|DRUG: Palonosetron Hydrochloride, 0.25 Mg/5 mL Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Rituximab Plus MG4101 Indolent CD20-positive Non-Hodgkin Lymphoma (NHL)
Status: TERMINATED
Conditions: CD20-positive Non-Hodgkin Lymphoma
Interventions: DRUG: Rituximab + MG4101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Painful Diabetic Peripheral Neuropathy
Interventions: DRUG: MT-8554 low dose|DRUG: MT-8554 middle dose|DRUG: MT-8554 high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT