pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Immunogenicity Study of Plasmodium Vivax CS Derived Synthetic Peptides Formulated in Two Adjuvants
Status: COMPLETED
Conditions: Malaria, Vivax
Interventions: DRUG: Peptides (N,R&C) formulated in Montanide ISA 720|DRUG: Peptides (N,R&C) formulated in Montanide ISA 51|DRUG: Peptides (N,R&C) formulated in Montanide ISA 720|DRUG: Peptides (N,R&C) formulated in Montanide ISA 51|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Secondary Prophylaxis of Hepatic Encephalopathy With a Probiotic Preparation
Status: COMPLETED
Conditions: Hepatic Encephalopathy
Interventions: DRUG: VSL#3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy With Cisplatin Versus Radiotherapy With Cetuximab After Induction Chemotherapy for Larynx Preservation
Status: COMPLETED
Conditions: Larynx Cancer|Hypopharynx Cancer
Interventions: DRUG: cetuximab|DRUG: Cisplatin|PROCEDURE: Radiotherapy 70 Gy, 35 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Utility of Serum Hepcidin Levels to Predict Response to Oral or IV Iron and to Compare Safety, Effect on Quality of Life, and Resource Utilization of Injectafer vs Intravenous Standard of Care for the Treatment of IDA in an Infusion Center Setting
Status: UNKNOWN
Conditions: Iron Deficiency Anemia (IDA)
Interventions: DRUG: Injectafer|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Low Calorie Ketogenic Low-fat Diet (VLCKLFD)
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Low-fat normoprotein Controlled Ketogenic Diet.|OTHER: Hypocaloric Balanced Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Bloodtranfusions After Aortic Surgery
Status: TERMINATED
Conditions: Hemorrhage|Thoracic Aneurysm
Interventions: DRUG: Haemocomplettan P|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiome in Lung Cancer and Other Malignancies
Status: COMPLETED
Conditions: Lung Cancer|Cancer|Malignancy
Interventions: PROCEDURE: Nasal Swab|PROCEDURE: Oral Swab|OTHER: Stool Collection|GENETIC: Microbiome analysis|GENETIC: DNA Banking|PROCEDURE: Skin Swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Two Exercises in Preventing Lower-Limb Lymphedema After Gynecological Cancer Surgery
Status: COMPLETED
Conditions: Lymphedema of Leg|Gynecologic Cancer|Exercise
Interventions: OTHER: Home-based exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Success Rate of Cryotherapy Application in Primary Molars With Signs of Irreversible Pulpitis
Status: UNKNOWN
Conditions: Pain, Procedural
Interventions: OTHER: Cryotherapy|OTHER: Traditional local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate Safety and Efficacy of Nuvastatic as an Immunomodulator Adjuvant Therapy in COVID-19 Patients.
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Nuvastatic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Prove Safety in Use (Irritability and Sensitization in Genital Mucosa) of an Intimate Lubricating Gel
Status: COMPLETED
Conditions: Female Dry Genital Mucosa
Interventions: DEVICE: KL029 Intimate Lubricant Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain
Status: TERMINATED
Conditions: Lumbar Spondylosis
Interventions: DEVICE: Angel® Concentrated Platelet Rich Plasma System|DRUG: Platelet Rich Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Treatment for Mixed Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Urinary Incontinence, Urge
Interventions: PROCEDURE: Miduretheral Sling|OTHER: Miduretheral Sling with behavioral/pelvic floor therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: Durvalumab|DRUG: Durvalumab and Tremelimumab|DRUG: Y-90 Selective Internal Radiation Therapy (SIRT)|DRUG: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization
Status: COMPLETED
Conditions: Uterine Leiomyomas
Interventions: DRUG: Lidocaine per-embolization|DRUG: Lidocaine post-embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Infection and Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Cerebrovascular Accident|Heart Diseases|Myocardial Infarction|Infection|Chlamydia Infections|Cytomegalovirus Infections|Helicobacter Infections|Atherosclerosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens
Status: COMPLETED
Conditions: End Stage Renal Failure With Renal Transplant
Interventions: DRUG: Tacrolimus with MMF|DRUG: Group 2: Tacrolimus with Everolimus.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Pharmacokinetic Study of Investigational Sublingual Nicotine Tablet Versus COMMIT Nicotine Lozenge
Status: COMPLETED
Conditions: Nicotine Pharmacokinetic Study
Interventions: DRUG: Nicotine (Pharmaceutical Productions Inc.)|DRUG: Nicotine (Pharmaceutical Productions Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Molidustat for Maintenance Treatment of Renal Anemia in Non-dialysis Subjects
Status: COMPLETED
Conditions: Anemia|Renal Insufficiency, Chronic
Interventions: DRUG: Molidustat (BAY85-3934)|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative RT & Anti-PD-1/PD-L1 Checkpoint Blockade in Metastatic Merkel Cell Carcinoma
Status: TERMINATED
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: Pembrolizumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thalidomide for the Treatment of Malnutrition Inflammation Syndrome in Peritoneal Dialysis Patients
Status: WITHDRAWN
Conditions: Peritoneal Dialysis|Malnutrition
Interventions: DRUG: thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Validity and Reproducibility of OSND (Objective Score of Nutrition on Dialysis) as a Nutritional Marker in End-stage Renal Disease
Status: UNKNOWN
Conditions: Malnutrition-Inflammation Syndrome|Hemodialysis Nutritional Risk Stratification
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Use of Palifermin to Treat Toxic Epidermal Necrolysis
Status: TERMINATED
Conditions: Toxic Epidermal Necrolysis|Stevens-Johnson Syndrome
Interventions: DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy is no More Risky in Emergent Cases With in Cardiopulmonary Risk: Fundus-Callot Cholecystectomy With Low Pressure Pneumo-peritoneum VS Open Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopy
Interventions: PROCEDURE: lap fundus-calot cholecystectomy|PROCEDURE: open cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of a New, Oral Growth Hormone Secretagogue, AEZS-130 as a Growth Hormone Stimulation Test.
Status: COMPLETED
Conditions: Diagnosis of Adult Growth Hormone Deficiency (AGDH)
Interventions: DRUG: AEZS-130 (formerly ARD-07)|DRUG: L-ARG+GHRH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: sipuleucel-T|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Superb Microvascular Imaging of Median Nerve in Carpal Tunnel Syndrome: A Novel Technique in Diagnostic Ultrasound
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome Bilateral
Interventions: DEVICE: Superb microvascular imaging (SMI) (Toshiba)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety Study of Vasopressin V2 Receptor Antagonist on Patients With Severe Chronic Heart Failure (AQUAVIT).
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Vasopressin V2 Receptor Antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotic Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: Yakult|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MELABLOCK: A Clinical Trial on the Efficacy and Safety of Propranolol 80 mg in Melanoma Patients
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nimotuzumab in Combination With External Radiotherapy in Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: PROCEDURE: External radiotherapy|BIOLOGICAL: nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Optic Nerve Sheath Diameter Measured by Ultrasonography Before and After Ventriculoperitoneal Shunt Surgery in Adult Patients With Hydrocephalus
Status: WITHDRAWN
Conditions: Hydrocephalus
Interventions: DEVICE: ultrasonographic measurement of optic nerve sheath diameter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics, Safety, and Tolerability of Ertugliflozin (MK-8835/PF-04971729) in Participants With Hepatic Impairment and in Healthy Participants (MK-8835-014)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hepatic Impairment
Interventions: DRUG: Ertugliflozin 15 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Fish Oils: Emulsified Versus Capsular Triglyceride
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Coromega Omega-3 Squeeze|DIETARY_SUPPLEMENT: Coromega Nectar|DIETARY_SUPPLEMENT: Barleans Swirl|DIETARY_SUPPLEMENT: Nordic Omega-3 Softgel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: M1231 in Participants With Solid Tumors
Status: COMPLETED
Conditions: Metastatic Solid Tumors|Esophageal Cancer|Non-Small Cell Lung Cancer
Interventions: DRUG: M1231|DRUG: M1231
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Surufatinib Combined With Gemcitabine and Albumin-bound Paclitaxel in the Peri-operative Treatment of Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: surufatinib + gemcitabine + nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Treatment Versus Non-surgical Treatment of Ulnar Fractures
Status: UNKNOWN
Conditions: Fracture|Trauma|Ulna Fracture|Orthopedic|Surgery
Interventions: PROCEDURE: Open reduction and internal fixation|PROCEDURE: Closed reduction and short-arm cast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy in Oligometastatic Brain Disease: a Randomised Phase III Study Comparing Hypofractionated Stereotactic Radiation Therapy (3*10 Gy) to the Historical Single-dose Radiosurgery (1*20 to 25 Gy) With Medico-economic Evaluation.
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastasis|Oligoprogression
Interventions: RADIATION: Hypofractionated SRT (stereotactic radiotherapy)|RADIATION: Historical single-dose SRS (stereotactic radiosurgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Deferasirox in Patients With Transfusion Dependent Iron Overload - a Non-comparative Extension Study
Status: COMPLETED
Conditions: Liver Iron Overload
Interventions: DRUG: Deferasirox|DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelial Progenitor Cells-capture Stents in Acute Coronary Syndromes
Status: COMPLETED
Conditions: Acute Coronary Syndromes|Coronary Heart Disease
Interventions: DEVICE: coronary stent (Genous, OrbusNeich) with immobilised anti-CD34 antibody to capture circulating endothelial progenitor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction/Simplification With Atazanavir + Ritonavir + Abacavir/Lamivudine Fixed-Dose Combination In HIV-1 Infection
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection
Interventions: DRUG: Abacavir (ABC)/lamivudine (3TC) + atazanavir (ATV) + ritonavir (/r)|DRUG: Abacavir (ABC)/lamivudine (3TC) + atazanavir (ATV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in Greece
Status: COMPLETED
Conditions: Choroidal Neovascularization|Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pegaspargase and Methotrexate Based Regimens for Newly Diagnosed Extranodal NK/T Cell Lymphoma
Status: COMPLETED
Conditions: Nasal Type Extranodal NK/T-Cell Lymphoma
Interventions: DRUG: Pegaspargase|DRUG: Methotrexate|DRUG: Dexamethasone|DRUG: Etoposide|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Handheld Ultrasound-assisted Versus Palpation-guided Labor Combined Spinal-epidural Analgesia
Status: COMPLETED
Conditions: Labor Analgesia
Interventions: DEVICE: handheld ultrasound-assisted technique|OTHER: conventional palpation-guided technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cryoablation Combined With Sintilimab Plus Lenvatinib In Previously Treated Unresectable Liver Metastasis From Solid Tumors
Status: RECRUITING
Conditions: Liver Metastasis
Interventions: DRUG: Sintilimab|DRUG: Lenvatinib|DRUG: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients
Status: UNKNOWN
Conditions: Hypercholesterolemia
Interventions: DRUG: Rosuvastatin/Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Standards of Care for Heart Failure Patients in General Practice - A Regional Disease Management Program
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Improved primary care HF diagnostics|OTHER: Heart Failure education|OTHER: Structured transitional protocol planning post-discharge care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Adjuvant Apalutamide in Subjects With High-risk Localized or Locally Advanced Prostate Cancer After Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: OTHER: Standard of care|DRUG: Apalutamide 60Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditions
Status: WITHDRAWN
Conditions: Infections, Bacterial
Interventions: DRUG: Cefixime test capsule|DRUG: Cefixime reference capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: the Efficacy and Safety of Diosmin on Non-diabetic Patients With Non-alcoholic Steatohepatitis.
Status: RECRUITING
Conditions: Non Alcoholic Steatohepatitis
Interventions: DRUG: Diosmin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Calcium β-hydroxy-β-methylbutyrate (CaHMB) Supplementation in Sarcopenia in Liver Cirrhosis
Status: UNKNOWN
Conditions: Sarcopenia|Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: CaHMB|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Guided Relaxation|OTHER: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gynecological Acceptability of 3 Health Care Products
Status: COMPLETED
Conditions: Atrophic Vaginitis|Vaginal Disease
Interventions: OTHER: Hyaluronic acid - Research product 1|OTHER: Hyaluronic acid - Research product 2|OTHER: Hyaluronic acid - Comparator product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous (SC) AMG 701 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: WITHDRAWN
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: AMG 701|DRUG: AMG 701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Progesterone for the Management of Preterm, Premature Rupture of the Membranes: A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Pregnancy Complications
Interventions: DRUG: 17-Hydroxyprogesterone Caproate|OTHER: Caster Oil injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Comparison Between FDG-PET/MR and FDG-PET/CT in Classical Hodgkin Lymphoma and DLBC Non-Hodgkin Lymphoma
Status: UNKNOWN
Conditions: Diffuse Large B-cell-lymphoma|Classical Hodgkin Lymphoma
Interventions: DIAGNOSTIC_TEST: FDG PET/TC and FDG PET/MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Correlation Among Sperm DNA Fragmentation, Genitourinary Infection by Mycoplasma in Male and the Pregnancy Outcomes After IUI in Their Partner
Status: UNKNOWN
Conditions: Mycoplasma
Interventions: PROCEDURE: IUI|PROCEDURE: IUI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: On the Move: Optimizing Participation in Group Exercise
Status: COMPLETED
Conditions: Physical Disability
Interventions: BEHAVIORAL: On the Move exercise - exercise leader|BEHAVIORAL: Standard program - exercise leader|BEHAVIORAL: On the Move exercise - staff activity personnel|BEHAVIORAL: Standard program - staff activity personnel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Oral Transmucosal Dexmedetomidine.
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: OTM Dexmedetomidine 1µg/ kg.|DRUG: OTM Dexmedetomidine 0.75µg/ kg.|DRUG: OTM Dexmedetomidine 0.5µg/ kg.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 62% & 15% Ethanol in Emollient Gel as Topical Male Microbicides
Status: COMPLETED
Conditions: Sexually Transmitted Infections
Interventions: OTHER: 62% ethanol in emollient gel|DRUG: Placebo|OTHER: 15% ethanol in emollient gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Osimertinib in Patients w/ Adv Solid Tumours & Normal Kidney Function or Severe Kidney Impairment
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Osimertinib; AZD9291
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood
Status: COMPLETED
Conditions: Typhoid|Paratyphoid Fever
Interventions: BIOLOGICAL: Typhoid Vi vaccine|BIOLOGICAL: Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Neuroendocrine Tumors (NETs) With Combination of Everolimus and Radiolabeled Somatostatin Analogue
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synek Score to Predict Poor Neurological Outcome Post Resuscitated Cardiac Arrest
Status: COMPLETED
Conditions: Prediction by the Synek Score of Poor Neurological Outcome in Postanoxic Comatose Patients Treated With Induced Hypothermia
Interventions: PROCEDURE: induced hypothermia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Pre-emptive Dose of Prednisone Versus Placebo in Impacted Third Molar Surgery
Status: COMPLETED
Conditions: Facial Swelling|Tooth Position Anomalies|Tooth, Impacted|Tooth Extraction Status Nos|Tooth Avulsion
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain
Status: COMPLETED
Conditions: Symptomatic Periapical Periodontitis
Interventions: DRUG: Amoxicillin/Clavulanate Potassium 875 mg-125 mg oral tablet|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Placebo Controlled Study to Assess the Effect of Rasagiline on Sleep-wake Disturbances in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Rasagiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Medial Humeral Epicondyle Fractures in Children With Absorbable Cartilage Nails
Status: COMPLETED
Conditions: Fracture Arm
Interventions: PROCEDURE: absorbable cartilage nail|PROCEDURE: traditional Kirschner wires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD19/BCMA Bispecific CAR-T Cell Therapy for R/R MM
Status: UNKNOWN
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma Progression
Interventions: BIOLOGICAL: anti-CD19/BCMA CAR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contactless Assessment of Patient Vital Signs for Triage Using Remote Photoplethysmography in the Emergency Department
Status: NOT_YET_RECRUITING
Conditions: Photoplethysmography|Vital Signs
Interventions: DIAGNOSTIC_TEST: Contactless measurement of patient vital signs using the VitalsTM system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: To Study the Mechanisms of Acupuncture Through Functional Magnetic Resonance Imaging and Peripheral Neurosensory Testing
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TREating Pediatric Obesity
Status: COMPLETED
Conditions: Infant Obesity|Hepatic Steatosis|Metabolic Syndrome|Insulin Resistance|Dyslipidemias
Interventions: BEHAVIORAL: Standard Care|BEHAVIORAL: Time restricted eating
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Superficial Basal Cell Cancer's Photodynamic Therapy: Comparing Three Photosensitizers: HAL and BF-200 ALA Versus MAL
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms, Basal Cell|Carcinoma, Basal Cell|Photochemotherapy|Photosensitizing Agents
Interventions: DRUG: Hexylaminolevulinate cream|DRUG: Aminolevulinic Acid Nano Emulsion|DRUG: Methylaminolevulinate cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-guided Large Diameter Lumen-apposing Metal Stent Gastro-gastrostomy for Bypass Reversal in Patients With Roux-en-y Gastric Bypass
Status: RECRUITING
Conditions: Hypoglycemia|Gastric Outlet Obstruction|Steatohepatitis|Parenteral Support|Gastric Bypass
Interventions: DEVICE: The Hot AXIOS™ Stent and Electrocautery-Enhanced Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of MONOtherapy of DOlutegravir in HIV-1 Virologically Suppressed Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|Dolutegravir|Monotherapy|Treatment Efficacy
Interventions: DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Self-Regulation in Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Dietary|BEHAVIORAL: Physical Activity|BEHAVIORAL: Self-Regulatory Approaches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: Synchrotope TA2M|BIOLOGICAL: Synchrotope TA2M|BIOLOGICAL: Synchrotope TA2M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of CSPH in Patients With cACLD
Status: RECRUITING
Conditions: Liver Cirrhosis|Liver Fibrosis|Portal Hypertension
Interventions: DIAGNOSTIC_TEST: Diagnostic Test: Transient elastography (TE) and 2D-shear wave elastography (2D-SWE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of G-CSF-Priming in Elderly AML Patients
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Etoposide|DRUG: Idarubicin|DRUG: G-CSF|DRUG: Fludarabine|PROCEDURE: Stem cell apheresis|PROCEDURE: Stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: De-roofing and Curettage vs WLE for Pilonidal Abscess
Status: UNKNOWN
Conditions: Pilonidal Abscess|Pilonidal Sinus With Abscess|Pilonidal Sinus Infected|Pilonidal Disease
Interventions: PROCEDURE: Abscess de-roofing and curettage|PROCEDURE: Abscess wide local excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Photorefractive Keratectomy and Corneal Cross-linking in Keratoconus
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Simultaneous Photorefractive Keratectomy and Collagen Cross-linking in patients with keratoconus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3b Study to Assess the Safety of Novartis Meningococcal B Recombinant Vaccine When Administered in Healthy At-risk Adults
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Recombinant meningococcal B + OMV NZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: V-Chordal Adjustable System for Chordal Replacement in Mitral Valve Insufficiency Due to Leaflet Prolapse
Status: TERMINATED
Conditions: Mitral Leaflet Prolapse
Interventions: DEVICE: V Chordal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Baclofen in the Treatment of People With Bulimia Nervosa or Binge Eating Disorder
Status: COMPLETED
Conditions: Eating Disorders|Bulimia Nervosa
Interventions: DRUG: Baclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance Study of Bevacizumab in Her2- Inflammatory Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Delivery Routes of Flu Vaccine in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Trivalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the TheraNova Neuromodulation System for the Treatment of Overactive Bladder Symptoms
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DEVICE: TheraNova Neuromodulation System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Intracranial Pressure Treatment Strategies for Chronic Subdural Hematoma Patients
Status: UNKNOWN
Conditions: Chronic Subdural Hematoma
Interventions: BEHAVIORAL: low intracranial pressure strategy treatment|DRUG: Atorvastatin plus Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Butamirate Citrate Syrup Versus (vs) Sinecod Syrup (Vanilla) in Adult Healthy Study Volunteers
Status: WITHDRAWN
Conditions: Healthy
Interventions: DRUG: Butamirate citrate|DRUG: Sinecod
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-individual Reproducibility in Nerve Block Duration
Status: COMPLETED
Conditions: Anesthesia, Regional
Interventions: DRUG: Infusion, Lidocaine, 0.5%, 5 mL|DRUG: Infusion, Lidocaine, 0.5%, 10 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance
Status: COMPLETED
Conditions: Ptosis, Eyelid|Conjunctiva Inflamed|Eye Manifestations
Interventions: DRUG: Oxymetazoline hydrochloride 0.1% ophthalmic solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cerebral Oxygenation on Postoperative Recovery in Intracranial Surgery
Status: UNKNOWN
Conditions: Intracranial Neoplasm
Interventions: DEVICE: cerebral oxygen monitoring|DEVICE: routine monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Lifestyle Behavior by "Joven, Fuerte y Saludable" Multidisciplinary Program.
Status: RECRUITING
Conditions: Breast Neoplasm
Interventions: BEHAVIORAL: Hybrid lifestyle educational multidisciplinary intervention.|BEHAVIORAL: Hybrid lifestyle personalized multidisciplinary intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognosis Value of Pro-adrenomedullin in Acute Exacerbations of COPD in ER
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive Patients Admitted in Emergency Department for Acute Exacerbation
Interventions: OTHER: AECOPD Mr proADM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating the Effects of DVS SR and Paroxetine on the Pharmacokinetics of Desipramine in Healthy Subjects
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: desvenlafaxine SR|DRUG: desipramine|DRUG: paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Projector Kaleidoscope and Cartoons on Anxiety, Fear, and Pain in Children
Status: NOT_YET_RECRUITING
Conditions: Anxiety and Fear|Pain|Surgery
Interventions: OTHER: Projector Kaleidoscope|OTHER: Cartoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Approved Drug to Study a New Indication for Allergic Rhinitis (0476-327)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: montelukast sodium|DRUG: Comparator: pranlukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Pharmacokinetics and Safety of Fimasartan and Amlodipine in Healthy Male Subjects
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Fimasartan/Amlodipine|DRUG: Fimasartan + Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Automated Oxygen Titration in Daily Life in Patients With COPD on Home Oxygen
Status: COMPLETED
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Interventions: OTHER: Automated oxygen titration based on the oxygen saturation during activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cyanoacrylate and Concentrated Growth Factor on Palatal Donor Site
Status: RECRUITING
Conditions: Wound Healing|Pain|Patient Comfort
Interventions: PROCEDURE: Free gingival graft procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Subiculum Electrical Stimulation for Temporal Lobe Epilepsy With Biliteral Hippocampus Sclerosis(SESTB)
Status: RECRUITING
Conditions: Epilepsy, Drug Resistant
Interventions: DEVICE: Subiculum-DBS ON
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammaging and Muscle Protein Metabolism
Status: COMPLETED
Conditions: Inflammaging|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Instantized Whey Protein Isolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Manual Therapy and Gastroesophageal Reflux Disease in Patients With Hiatal Hernia
Status: UNKNOWN
Conditions: Gastroesophageal Reflux
Interventions: OTHER: Osteopathic Medicine|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)
Status: UNKNOWN
Conditions: Leukemia|Acute Myeloid Leukemia|Relapsed/Refractory Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: MAX-40279-01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib, Obinutuzumab and Venetoclax for Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia|B-Cell Chronic Lymphocytic Leukemia in Relapse (Diagnosis)
Interventions: DRUG: Ibrutinib|DRUG: Obinutuzumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SATIN The Acute Effect of Orange Nectar With NAXUS Fibre Made by Novel Processing on Satiety and Satiation
Status: COMPLETED
Conditions: Appetite
Interventions: DIETARY_SUPPLEMENT: Orange nectar|DIETARY_SUPPLEMENT: Orange Nectar with fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Effect of Rifampicin on Blood Levels and Safety of AZD9291, in Patients With EGFRm+ NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: PROCEDURE: Pharmacokinetic sampling - AZD9291|DRUG: Rifampicin|DRUG: AZD9291 tablet dosing|PROCEDURE: Pharmacokinetic sampling - rifampicin|PROCEDURE: Pharmacokinetic sampling - AZ5140 and AZ7550
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: OTHER
Clinical trial: Varenicline for Adolescent Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Varenicline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Randomized, Pivotal, Bioequivalence Study of Oral and Intravenous Rolapitant
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Rolapitant - Oral|DRUG: Rolapitant - IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First-line Chemotherapy for Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Recurrent Cervical Carcinoma|Persistent Advanced Cervical Carcinoma|Chemotherapy|Vascular Endothelial Growth Factor 2 Inhibitor|Apatinib|Targeted Therapy
Interventions: DRUG: Chemotherapy plus apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cios Mobile 3D Spin for Robotic Bronchoscopy
Status: COMPLETED
Conditions: Pulmonary Nodule, Solitary|Pulmonary Cancer|Lung Cancer|Lung Cancer, Nonsmall Cell|Lung Adenocarcinoma
Interventions: DIAGNOSTIC_TEST: Ion Endoluminal System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anesthesia and Cancer Recurrence im Malignant Melanoma
Status: UNKNOWN
Conditions: Malignant Melanoma
Interventions: PROCEDURE: Spinal anesthesia with Bupivacaine hyperbar 0.5 %|PROCEDURE: General anesthesia with Sufentanil, Propofol and Rocuronium and Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Castration-Resistant Prostate Carcinoma|Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Metastatic Prostate Carcinoma|Prostate Carcinoma Metastatic in the Bone|Refractory Malignant Solid Neoplasm|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Avelumab|BIOLOGICAL: Ivuxolimab|RADIATION: Radiation Therapy|BIOLOGICAL: Utomilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myocardial Infarction - Stress Prevention Intervention
Status: TERMINATED
Conditions: Stress Disorders, Post-Traumatic|Myocardial Infarction
Interventions: BEHAVIORAL: Minimal behavioral intervention|BEHAVIORAL: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Avastin|PROCEDURE: Photodynamic Therapy (PDT)|DRUG: Preservative-Free Triamcinolone Acetonide (TAC-PF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Difficult Laryngoscopy With Ultrasonography in Pediatric Patients
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Difficult Laryngoscopy
Interventions: DIAGNOSTIC_TEST: Distance between Skin-Hyoid Bone(DSHB)|DIAGNOSTIC_TEST: Distance between Skin-Vocal Cord Anterior Commissura(DSAC)|DIAGNOSTIC_TEST: Distance between Skin-Epiglottic(DSE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EBUS TBNA After PET/CT in Diagnosing Patients With Stage I-IIA Non-small Cell Lung Cancer Evaluated for Stereotactic Body Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: PROCEDURE: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EValuation of the Antioxidant and Anti-inflammatory Capacity of Nutraceutical IMMU·SYSTEM Food Supplement (EVAANIS)
Status: COMPLETED
Conditions: Oxidative Stress
Interventions: DIETARY_SUPPLEMENT: Immusystem|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION