pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Telephone Feedback System for Prevention of Chronic Pain Relapse
Status: COMPLETED
Conditions: Chronic Pain and Relapse Prevention
Interventions: BEHAVIORAL: Chronic pain therapeutic interactive voice response (TIVR) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Positive Parenting Program for Women Experiencing Homelessness Who Have a History of Interpersonal Violence
Status: NOT_YET_RECRUITING
Conditions: Interpersonal Violence|Homelessness
Interventions: BEHAVIORAL: Positive Parenting Program|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study to Assess the Equivalence of Tranexamic Acid vs Oxytocin in Reducing the PPH
Status: COMPLETED
Conditions: Post Partum Haemorrhage
Interventions: DRUG: Tranexamic Acid|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PK and Safety of the LicartTM Topical System in Pediatric and Adult Participants With Minor Soft Tissue Injury
Status: RECRUITING
Conditions: Soft Tissue Injuries
Interventions: DRUG: Licart™ (diclofenac epolamine) topical system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Erector Spinae Plane Block (ESPB) in Laparoscopic Cholecystectomies
Status: COMPLETED
Conditions: Pain, Postoperative|Pain Syndrome|Pain, Acute|Anesthesia|Cholecystectomy|Erector Spinae Plane Block
Interventions: PROCEDURE: Group Dexmedetomidine|PROCEDURE: Group Ropivacaine|PROCEDURE: Group Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Multiple Doses of ALXN1210 in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALXN1210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supine MRI in Breast Cancer Patients Undergoing Upfront Surgery or Receiving Neoadjuvant Therapy
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Supine MRI|OTHER: Neoadjuvant Therapy (NAT)|DEVICE: Ultrasound|DEVICE: Mammography|PROCEDURE: Standard of Care|DEVICE: Standard MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Audiovisual Aid Pilot Study
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: DEVICE: Zeiss, Cinema ProMED (audiovisual equipment)|DRUG: Midazolam|DEVICE: Skin Conductance Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma|Sarcoma
Interventions: DRUG: Cyclophosphamide, Topotecan, and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy
Status: RECRUITING
Conditions: Primary Sclerosing Cholangitis|Cholestasis
Interventions: DRUG: Bezafibrate (400mg) in addition to standard 15-20 mg/kg/jour UDCA therapy|DRUG: Placebo of Bezafibrate in addition to standard UDCA therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Creating Physical Objects With 3D Printers to Stimulate Reminiscing for Memory Loss [2 R44 AG049548-02A1]
Status: UNKNOWN
Conditions: Dementia
Interventions: BEHAVIORAL: 3D-RT|BEHAVIORAL: RT-Verbal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring of patIents With Microdialysis Following Pancreaticoduodenectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Pancreatic Neoplasms|Biliary Tract Cancer|Duodenal Cancer|Pancreatic Fistula
Interventions: PROCEDURE: Surgical og radiological intervention, antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Analysis and Applications of Dynamic Impression Insole
Status: COMPLETED
Conditions: Metatarsalgia
Interventions: PROCEDURE: Dynamic impression insole|PROCEDURE: Custom molded insole|PROCEDURE: 9-mm uncompressed Plastazote|PROCEDURE: 7-mm Ethylene Vinyl Acetate (EVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Pemetrexed Plus Cisplatin With Concurrent Radiation Therapy Followed by Docetaxel Consolidation in Patients With Inoperable Squamous Cell Lung Cancer
Status: UNKNOWN
Conditions: Squamous Cell Lung Cancer
Interventions: DRUG: pemetrexed|DRUG: cisplatin|RADIATION: thoracic radiation therapy|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Chidamide Combined With CHOP in Peripheral T-cell Lymphoma Patients
Status: COMPLETED
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: Chidamide|DRUG: cyclophosphamide|DRUG: adriacin|DRUG: vincristine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Taspoglutide in Patients With Inadequately Controlled Diabetes Mellitus Type 2 and Cardiovascular Disease
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: placebo|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tobramycin solution for inhalation (TOBI)|DRUG: Oral placebo|DRUG: Oral ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Steady State Bioequivalence Study of Torrent Pharmaceuticals Ltd's Bioequivalence Study of Torrent Pharmaceuticals Ltd's Quetiapine Tablets
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Torrent's Quetiapine Fumarate Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Testing the Safety and Effectiveness of Combining Two Drugs, PLX2853 and Trametinib in the Treatment of Advanced Uveal Melanoma
Status: WITHDRAWN
Conditions: Advanced Uveal Melanoma|Metastatic Uveal Melanoma|Unresectable Uveal Melanoma
Interventions: DRUG: BRD4 Inhibitor PLX2853|DRUG: Trametinib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Biospecimen collection|PROCEDURE: Biospecimen collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Knee Pain
Interventions: DRUG: Botulinum toxin A|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Efficacy and Safety of INS068 and Insulin Glargine in Subjects With Type 2 Diabetes Mellitus Treated With Basal Insulin.
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INS068 injection|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic Neuromodulation (ANM) for Youth With Anxiety Disorders
Status: TERMINATED
Conditions: Separation Anxiety Disorder|Generalized Anxiety Disorder|Social Phobia
Interventions: OTHER: Acoustic Neuromodulation (ANM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma of Unknown Primary
Interventions: DRUG: Pembrolizumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Study of Elotuzumab in High Risk Smoldering Myeloma
Status: COMPLETED
Conditions: Smoldering Multiple Myeloma
Interventions: BIOLOGICAL: Elotuzumab (BMS-901608; HuLuc63)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Placebo (for Dronedarone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Casein Protein and Leucine Supplementation in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: COPD
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed casein protein|DIETARY_SUPPLEMENT: Hydrolyzed casein protein + carbohydrates|DIETARY_SUPPLEMENT: Hydrolyzed casein protein + leucine|DIETARY_SUPPLEMENT: Hydrolyzed casein protein + carbohydrates + leucine|DIETARY_SUPPLEMENT: 4 levels of hydrolyzed casein protein + carbohydrates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: REmission in Membranous Nephropathy International Trial (REMIT)
Status: NOT_YET_RECRUITING
Conditions: Primary Membranous Nephropathy
Interventions: DRUG: Obinutuzumab|DRUG: Oral prednisolone and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients Following Surgery for Stage III Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: FOLFIRI regimen|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Monthly Risedronate for Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: risedronate|DRUG: risedronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery
Status: COMPLETED
Conditions: Lumbar Surgery
Interventions: DEVICE: Provant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fuerte Program for Newcomer Immigrant Youth
Status: ENROLLING_BY_INVITATION
Conditions: Trauma, Psychological|Mental Disorder in Adolescence|Adolescent - Emotional Problem
Interventions: BEHAVIORAL: Fuerte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Written Exposure Therapy for Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Written Exposure Therapy|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosis Screening in Juvenile Justice
Status: COMPLETED
Conditions: Psychotic Disorders|Psychosis Nos/Other
Interventions: BEHAVIORAL: Enhanced Referral/Linkage to Care|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices
Status: UNKNOWN
Conditions: Acute Kidney Injury|Cirrhosis|Esophageal Varices
Interventions: DRUG: propranolol|PROCEDURE: Esophageal varice ligation|OTHER: DC propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Individual Mindfulness-based Intervention for Cancer Patients in a Advanced Stage of the Disease and Their Relatives
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Emotional Supportive Mindfulness-based Program|BEHAVIORAL: Emotional Supportive Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analgesic Effect of Acupuncture for Patients With Rib Fractures
Status: COMPLETED
Conditions: Rib Fractures|Acute Pain|Analgesia
Interventions: PROCEDURE: Traditional acupuncture (TA)|PROCEDURE: Laser acupuncture (LA)|PROCEDURE: Sham laser acupuncture (SLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of the Coadministration of LY2216684 With Sertraline
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2216684|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gadopiclenol for Magnetic Resonance Imaging (MRI) in Japanese Adults and Children
Status: RECRUITING
Conditions: Lesion in Body Region|CNS Lesion
Interventions: DRUG: Gadopiclenol|DRUG: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myelogenous Leukemia|B-cell Chronic Lymphocytic Leukemia|Chronic Myelogenous Leukemia|Myelodysplasia
Interventions: DRUG: ABT-348|DRUG: ABT-348|DRUG: ABT-348 and azacitidine|DRUG: ABT-348
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)
Status: TERMINATED
Conditions: Chronic Graft-Versus-Host Disease|Acute Graft-Versus-Host Disease|Steroid Refractory Graft-Versus-Host Disease
Interventions: DRUG: Rapamycin|OTHER: T regulatory cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Allogeneic ABCB5-positive Stem Cells for Treatment of PAOD
Status: TERMINATED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: BIOLOGICAL: allo-APZ2-PAOD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Z160 in Subjects With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Z160|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Assess the Safety and Pharmacokinetic of Pegylated Somatropin(PEG Somatropin) in GHD Children
Status: COMPLETED
Conditions: Growth Hormone Deficiency
Interventions: DRUG: somatropin AQ|DRUG: pegylated somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ACZ885 in Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease
Status: COMPLETED
Conditions: Cryopyrin-Associated Periodic Syndromes|Familial Cold Autoinflammatory Syndrome|Muckle Wells Syndrome|Neonatal Onset Multisystem Inflammatory Disease
Interventions: DRUG: Canakinumab (ACZ885)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmaco-Economic Study Of Ultiva In Intensive Care Unit(ICU)Subjects
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: midazolam|DRUG: lorazepam|DRUG: fentanyl|DRUG: morphine|DRUG: remifentanil|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of L-Carnitine on Gastric Emptying in Children With Drug Resistant Epilepsy on Ketogenic Diet
Status: COMPLETED
Conditions: Ketogenic Diet
Interventions: DIETARY_SUPPLEMENT: L- Carnitine|OTHER: ketogenic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Effectiness and Safety of Levofloxacin in Treating Children With a Rapid and Severe Onset of Infection and Inflammation of the Middle Ear That is Difficult to Treat
Status: COMPLETED
Conditions: Otitis Media
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib Plus TAS102 in mCRC as Salvage Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Colorectal Carcinoma|Metastatic Cancer|CRC
Interventions: DRUG: Cabozantinib|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Active Versus Passive Recharge Burst Spinal Cord Stimulation on Pain Experience in Persistent Spinal Pain Syndrome Type 2: A Multicenter Randomized Trial (BURST-RAP Study)
Status: RECRUITING
Conditions: Persistent Spinal Pain Syndrome Type 2|Failed Back Surgery Syndrome
Interventions: DEVICE: Spinal cord stimulation using passive recharge burst stimulation|DEVICE: Spinal cord stimulation using active recharge burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of LIPUS on the Maturation of Newly Constructed Autogenous AVF
Status: RECRUITING
Conditions: Uremia; Chronic
Interventions: DEVICE: Low intensity pulse ultrasound （LIPUS） intervention for arteriovenous fistula anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Impact of Diet on Medical Conditions Treated Within Bundled Payment Models: a Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Hypertension|Type 2 Diabetes|Obesity
Interventions: OTHER: Low-energy diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Modified Transversus Thoracic Muscle Plane Block and Erector Spinal Muscle Plane Block in Heart Valve Replacement Surgery With Median Incision
Status: RECRUITING
Conditions: Anesthesia
Interventions: PROCEDURE: Transversus thoracic muscle plane block or Erector spinal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer Who Have Previously Received a Trastuzumab-Containing Regimen
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: trastuzumab-MCC-DM1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pectin Supplemented Enteral Feedings in Critically Ill Patients
Status: WITHDRAWN
Conditions: Enteral Nutrition|Dietary Fiber
Interventions: DIETARY_SUPPLEMENT: pectin-supplemented enteral nutrition feeding|OTHER: enteral nutrition feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Trial of ZX-7101A Tablets to Evaluate the Efficacy and Safety in the Treatment of Uncomplicated Influenza in Adolescents
Status: NOT_YET_RECRUITING
Conditions: Respiratory Viral Infection
Interventions: DRUG: ZX-7101A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety of and Immune Response to an Experimental HIV Vaccine (VRC-HIVADV014-00-VP) in HIV Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVADV014-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Triflusal on Peripheral Microcirculation Dysfunction
Status: COMPLETED
Conditions: Vasospastic Syndrome
Interventions: DRUG: Triflusal|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Selenium Therapy for the Prevention of Mucositis
Status: UNKNOWN
Conditions: Mucositis|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Oral selenium|DRUG: Oral placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multicenter Study for Isolated Skin Vasculitis
Status: RECRUITING
Conditions: Primary Cutaneous Vasculitis|Cutaneous Polyarteritis Nodosa|IgA Vasculitis|Henoch-Schönlein Purpura
Interventions: DRUG: Colchicine|DRUG: Dapsone|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesio-taping in Knee Osteoarthritis Patients.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: kinesio-taping with conventional therapy 24 hours|OTHER: kinesio-taping with conventional therapy 48 hours|OTHER: kinesio-taping with conventional therapy 72 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Robot Assisted Hand Therapy in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Tetraplegia
Interventions: PROCEDURE: Robot Assisted Therapy|PROCEDURE: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PK of Efavirenz & Lopinavir Nano-formulations in Healthy Volunteers
Status: SUSPENDED
Conditions: HIV
Interventions: DRUG: 50mg NANO-efavirenz|DRUG: 400mg NANO-Lopinavir|DRUG: 200mg NANO-Lopinavir|DRUG: 100mg Ritonavir|DRUG: 300mg NANO-Efavirenz|DRUG: 600mg Sustiva|DRUG: 200mg NANO-Efavirenz|DRUG: Kaletra® (lopinavir 400mg/ritonavir 100mg)|DRUG: +/- 200mg NANO-Lopinavir|DRUG: +/- 200mg ritonavir NORVIR|DRUG: 400mg Sustiva
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Aspirin and Postpartum Vascular Function
Status: RECRUITING
Conditions: Preeclampsia|Microvascular Function
Interventions: DRUG: Acetylcholine|DRUG: Endothelin-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Mindfulness on Pain After Total Knee Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Total Knee Replacement|Post Operative Pain|Opioid Use
Interventions: OTHER: Headspace|PROCEDURE: Total Knee Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Empagliflozin 10 mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Head and Neck Position About Oropharyngeal Leak Pressure and Sealing Between the Laryngeal Mask and Vocal Cord Using Different Types of Supraglottic Airway Device
Status: COMPLETED
Conditions: the Influence of Oropharyngeal Leak Pressure and Sealing Between the Mask and Vocal Cord During Changing Patient's Head and Neck Position
Interventions: DEVICE: LMA proseal|DEVICE: igel LMA|DEVICE: air Q LMA|DEVICE: ambu LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: GM-CSF, Sargramostim in Women With Recurrent Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer
Interventions: DRUG: GM-CSF, sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension
Interventions: DRUG: Oxygen|DRUG: Room air
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choice Architecture and Mailed Colorectal Cancer Screening Outreach in a Community Health Setting
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Colonoscopy Only|BEHAVIORAL: Choice|BEHAVIORAL: FIT Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hyperinsulinemic Normoglycemic Clamp for Pancreas and Simultaneous Pancreas/Kidney Transplant Recipients
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: OTHER: Hyperinsulinemic Normoglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy Study of HU-014 Versus Botox® in Subject With Moderate to Severe Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: BIOLOGICAL: HU-014 Inj|BIOLOGICAL: Botox Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Povidone-Iodine for Nasal Decolonization
Status: COMPLETED
Conditions: Surgical Wound Infection|Preoperative Care|Methicillin-Resistant Staphylococcus Aureus
Interventions: DRUG: Povidone-Iodine 10%|DRUG: 0.9% NaCl Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prebiotic Effects of Isomalto-oligosaccharide
Status: COMPLETED
Conditions: Microbiota
Interventions: DIETARY_SUPPLEMENT: Isomalto-oligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Real-world Outcomes on Tecfidera (BG00012, Dimethyl Fumarate) Post-Tysabri (BG00002, Natalizumab)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: BIOLOGICAL: natalizumab|DRUG: dimethyl fumarate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetic Study of JNJ-42756493 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-42756493 10 mg tablet|DRUG: JNJ-42756493 10 mg Oral Solution|DRUG: JNJ-61818549
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-site Confirmatory Efficacy Treatment Trial of Combat-related PTSD
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DEVICE: Active rTMS|DEVICE: Sham rTMS|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is There a Relation Between Unilateral Epidural Block and Repeated Epidural Anesthesia?
Status: COMPLETED
Conditions: Incidence|Unilateral|Epidural Block
Interventions: DRUG: marcaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of High-intensity Aerobic Interval Training on Impairments and Activity Limitations in the Acute Phase of Stroke in Benin
Status: RECRUITING
Conditions: Stroke, Acute
Interventions: OTHER: HIIT-RCE|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease
Status: COMPLETED
Conditions: Rheumatic Heart Disease|Pregnancy|Dental Caries
Interventions: PROCEDURE: Dental local anesthesia|PROCEDURE: Dental local anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Lumacaftor in Combination With Ivacaftor in Subjects With CF, Homozygous for the F508del-CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: VX-809|DRUG: Placebo|DRUG: VX-770
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral HPV Infection in Young Men
Status: COMPLETED
Conditions: Head and Neck Cancer|Infection|Precancerous Condition
Interventions: GENETIC: comparative genomic hybridization|GENETIC: gene expression analysis|OTHER: study of socioeconomic and demographic variables|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease (AD)
Interventions: DRUG: Zagotenemab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Objective Evaluation of the Scratch Collapse Test With Dynamometer, a Prospective Multicenter Trial.
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Ulnar Nerve Compression
Interventions: DIAGNOSTIC_TEST: Scratch collapse test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diet, Cardiometabolic Risk (CM) and Menopause Symptoms
Status: COMPLETED
Conditions: Metabolic Syndrome, Protection Against|Menopause
Interventions: OTHER: The impact of MedDiet on cardiometabolic risk factors and menopause symptoms|OTHER: The impact of UCLP on cardiometabolic risk factors and menopause symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AS101 to Treat Elderly Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Patients
Status: SUSPENDED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: AS101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PErsonalized TREatment of High-risk MAmmary Cancer - the PETREMAC Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Neoadjuvant tamoxifen + goserelin (premenopausal women)|DRUG: Neoadjuvant letrozole (postmenopausal women)|DRUG: Neoadjuvant endocrine therapy + palbociclib (if lack of response to endocrine therapy alone)|DRUG: Neoadjuvant docetaxel + cyclophosphamide|DRUG: Neoadjuvant docetaxel|DRUG: Neoadjuvant docetaxel + trastuzumab + pertuzumab|DRUG: Neoadjuvant docetaxel + cyclophosphamide + trastuzumab + pertuzumab|DRUG: Neoadjuvant olaparib|DRUG: Neoadjuvant cyclophosphamide (after 10 weeks of olaparib alone)|PROCEDURE: Breast conserving surgery or mastectomy + SNB/axillary dissection|RADIATION: Postoperative radiotherapy breast/chest wall + regional lymph nodes|DRUG: Adjuvant trastuzumab|DRUG: Adjuvant letrozole (postmenopausal women)|DRUG: Adjuvant tamoxifen + goserelin (premenopausal women)|DRUG: Adjuvant palbociclib (if palbociclib given neoadjuvant)|DRUG: Adjuvant Epirubicin+ Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sono-Electro-Magnetic Therapy for Refractory Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DEVICE: sono-electro-magnetic therapy (Sonodyn Medico Star)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: everolimus|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Diseases|Multivessel Coronary Artery Disease|Heart Diseases|Cardiovascular Diseases
Interventions: RADIATION: Coronary Angiography|RADIATION: Computed Tomography (CT) scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit
Status: COMPLETED
Conditions: Gastric Emptying|Healthy
Interventions: DRUG: Dexmedetomidine|DRUG: Morphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Assessment of Plasma Lactate in Non-cardiac Surgery Monitoring by Transthoracic Echocardiography
Status: UNKNOWN
Conditions: Anesthesia
Interventions: DEVICE: Conventional monitor|DEVICE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise and Healthy Diet or Standard Care in Patients in Remission From Stage I or Stage II Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|BEHAVIORAL: exercise intervention|OTHER: counseling intervention|OTHER: educational intervention|OTHER: survey administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Rivaroxaban or Aspirin As Thromboprophylaxis in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma Progression|Multiple Myeloma Stage II|Multiple Myeloma Stage I|Multiple Myeloma With Failed Remission|Multiple Myeloma Stage III
Interventions: DRUG: Rivaroxaban|DRUG: ASA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes|Gestational Diabetes|Preeclampsia|Gestational Hypertension|Small for Gestational Age at Delivery|Preterm Birth|Overweight and Obesity
Interventions: BEHAVIORAL: Fit After Baby|BEHAVIORAL: Text4Baby Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Determine Efficacy of Cyclamen Europaeum Extract Nasal Spray in Patients With Acute Sinusitis
Status: COMPLETED
Conditions: ACUTE SINUSITIS
Interventions: DRUG: Cyclamen Europaeum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study to Compare the Efficacy and Safety of Belotecan and Topotecan as Monotherapy for Sensitive-Relapsed Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Topotecan|DRUG: Belotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Frexalimab|DRUG: Teriflunomide|DRUG: Placebo infusion|DRUG: Placebo tablet|DRUG: MRI contrast-enhancing agents|DRUG: Cholestyramine|DRUG: Activated charcoal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of rTSMS Associated With Treadmill Training in Patients With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Gait Disorders, Neurologic
Interventions: OTHER: Active stimulation- intermittent theta-burst (iTBS) stimulation|OTHER: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib Plus AI (Neoadjuvant Endocrine Therapy) Compared With Neoadjuvant Chemotherapy in Early Breast Cancer （EBC）
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Aromatase inhibitor|DRUG: Docetaxel injection|DRUG: Epirubicin Hydrochloride Injection|DRUG: Cyclophosphamide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 4-Point Therapy Response Score With PET/CT for Anal Squamous Cell Cancer
Status: COMPLETED
Conditions: Anal Squamous Cell Carcinoma|Stage 0 Anal Cancer AJCC v8|Stage I Anal Cancer AJCC v8|Stage II Anal Cancer AJCC v8|Stage IIA Anal Cancer AJCC v8|Stage IIB Anal Cancer AJCC v8|Stage III Anal Cancer AJCC v8|Stage IIIA Anal Cancer AJCC v8|Stage IIIB Anal Cancer AJCC v8|Stage IIIC Anal Cancer AJCC v8
Interventions: PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|PROCEDURE: Follow-Up|PROCEDURE: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on Pulmonary Rehabilitation for Stable Chronic Obstructive Pulmonary Disease(COPD) Patients
Status: UNKNOWN
Conditions: Nutritional Support|Aerobic Exercise|Respiratory Function Tests|Body Composition|Muscle Strength
Interventions: DIETARY_SUPPLEMENT: oral nutritional supplements|BEHAVIORAL: rehabilitation exercise|OTHER: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Native T1 CMR Imaging for Diagnosis of Cardiac Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure NYHA Class II|Heart Failure NYHA Class III|Heart Failure NYHA Class IV|Heart Failure With Preserved Ejection Fraction|Heart Failure With Mid Range Ejection Fraction|Hypertrophy, Left Ventricular|Cardiac Amyloidosis
Interventions: DIAGNOSTIC_TEST: Native T1 CMR|DIAGNOSTIC_TEST: Web-based ATTR probability estimator (Pfizer, New York)|DIAGNOSTIC_TEST: 99mTc-DPD scintigraphy|DIAGNOSTIC_TEST: Laboratory screening for multiple myeloma / AL amyloidosis|PROCEDURE: Cardiac biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Nordic Walking and Exercise on Glucose Metabolism in Type 2 Diabetes Mellitus: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Type 2 Diabetes|Exercise
Interventions: BEHAVIORAL: Exercise on Prescription|BEHAVIORAL: Nordic Walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Azithromycin Tablets 600 mg to Zithromax® Tablets 600 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Azithromycin Tablets 600 mg|DRUG: Zithromax® Tablets 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RDRI and NGAL in Acute Kidney Injury in Abdominal Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Neutrophil Gelatinase-Associated Lipocalin|DIAGNOSTIC_TEST: Renal Doppler Resistive Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies
Status: TERMINATED
Conditions: ALL|Burkitt's Lymphoma|Lymphoblastic Leukemia|CML
Interventions: DRUG: Rapamycin + high dose etoposide and cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Pneumoperitoneum Pressure in Colorectal Laparoscopic Surgery Versus Standard Therapy (IPPCollapse-II)
Status: COMPLETED
Conditions: Colorectal Surgery|Laparoscopy
Interventions: PROCEDURE: IPP in colorectal laparoscopic surgery|PROCEDURE: SPP in colorectal laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Azacitidine|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|OTHER: Questionnaire Administration|BIOLOGICAL: Tagraxofusp-erzs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation of Frail Surgical Cancer Patients Using Remote Ischemic Preconditioning
Status: COMPLETED
Conditions: Colon Cancer|Fragility|Prehabilitaiton|Surgery
Interventions: PROCEDURE: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Understanding Genetic Risk for Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Alcohol use disorder and strategies to reduce risk educational material|BEHAVIORAL: Complex polygenic risk scores, alcohol use disorder, and strategies to reduce risk educational material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inflammation and Clotting Abnormalities in Aneurysmal Coronary Artery Disease
Status: RECRUITING
Conditions: Coronary Artery Aneurysm|Abdominal Aortic Aneurysm|Coronary Disease
Interventions: OTHER: Evaluation of inflammation and clotting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: L-arginine Study for Persistent Symptoms of Schizophrenia
Status: WITHDRAWN
Conditions: Schizo Affective Disorder|Schizophrenia
Interventions: DRUG: L-arginine|DRUG: Sapropterin Dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT