pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of CAT-2003
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: CAT 2003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson's Disease
Status: UNKNOWN
Conditions: Idiopathic Parkinson Disease|Primary Parkinsonism
Interventions: DRUG: Mesencephalic Neuronal Precursor Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AHA (American Heart Association) Food is Medicine Test of Choice Architecture and Salience of Incentives
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Diabetes
Interventions: BEHAVIORAL: Storefront Choice Architecture|BEHAVIORAL: Fresh Funds|BEHAVIORAL: Loss Framing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Pharmacology Trial of Brexpiprazole Long Acting Injectable (LAI) Administered as a Single Dose in Patients With Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole LAI: Dose 1|DRUG: Brexpiprazole LAI: Dose 2|DRUG: Brexpiprazole LAI: Dose 3|DRUG: Brexpiprazole LAI: Dose 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 1|Diabetic Ketoacidosis
Interventions: DRUG: Glargine|DRUG: IV insulin|OTHER: Electrolyte Correction|OTHER: Correction of Fluid Loss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Status: RECRUITING
Conditions: Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Methylprednisone/Prednisone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Management of Pressure and Volume Expansion in Patients With Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Subarachnoid Hemorrhage
Interventions: OTHER: Fluid manipulation|OTHER: Blood Pressure Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Tiotropium Inhalation Capsules and Salmeterol Inhalation Aerosol on Muscular Efficiency and Resting Energy Expenditure (REE) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DRUG: Placebo to tiotropium|DRUG: Salmeterol|DRUG: Placebo to salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Latvian Early Atherosclerosis Registry
Status: RECRUITING
Conditions: Coronary Artery Disease|Atherosclerosis, Coronary
Interventions: DIAGNOSTIC_TEST: Near infrared spectroscopy|GENETIC: Genetic testing for LDLR, APOB, PCSK9 and LDLRAP1 mutations and niR-126, -145 and -155 expression.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The MICHI NEUROPROTECTION SYSTEM: Evaluation of Performance in Carotid Artery Stent Procedures (The LOTUS Study)
Status: COMPLETED
Conditions: Carotid Stenosis|Carotid Artery Disease
Interventions: DEVICE: MICHI Neuroprotection System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Response Evaluation in Patients With Non-resectable Colorectal Liver Metastases A Feasibility Study
Status: UNKNOWN
Conditions: Liver Metastasis Colon Cancer
Interventions: PROCEDURE: liver biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Romiplostim, Rituximab and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia|Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: Romiplostim|DRUG: Rituximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging
Status: COMPLETED
Conditions: Photoaging
Interventions: OTHER: Hexylresourcinol|OTHER: Hydroquinone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Overhead Perturbation Training for Glenohumeral Joint Instability
Status: UNKNOWN
Conditions: Exercise Movement Techniques|Shoulder Pain|Glenohumeral Subluxation
Interventions: OTHER: Overhead perturbation training|OTHER: Non-perturbed training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea|OSA|Apnea|Apnea, Obstructive|Apnea, Obstructive Sleep|Apnea+Hypopnea|Hypopnea, Sleep
Interventions: DEVICE: Hypoglossal Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Effectiveness of Non-ablative Er: YAG Laser for Treatment of Stress Urinary Incontinence (SUI)
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Non-ablative thermal-only Er:YAG laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Between Fluticasone and Salmeterol vs. SERETIDE DISKUS® in Healthy Volunteers With Charcoal Blockade
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Test Product (Fluticasone propionate and salmeterol xinafoate inhalation powder/Respirent Pharmaceuticals)|DRUG: Reference Product (SERETIDE DISKUS® 100/50 inhalation powder/GSK)|OTHER: Activated Charcoal suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Terameprocol in Treating Patients With Recurrent High Grade Glioma
Status: COMPLETED
Conditions: High Grade Glioma (III or IV)
Interventions: DRUG: Terameprocol|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambu® Laryngeal Mask as an Intubation Conduit
Status: COMPLETED
Conditions: Intubation, Endotracheal
Interventions: DEVICE: Ambu Laryngeal Mask|DEVICE: Aintree Exchange Catheter|DEVICE: Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Trial of Acupuncture in the Treatment of Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia|Diffuse Myofascial Pain Syndrome|Fibromyalgia-Fibromyositis Syndrome|Fibromyositis-Fibromyalgia Syndrome|Myofascial Pain Syndrome, Diffuse
Interventions: PROCEDURE: Acupuncture|BEHAVIORAL: Orientation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]
Status: COMPLETED
Conditions: Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab (MPDL3280A), an engineered anti-programmed death-ligand 1 (anti-PD-L1) antibody|DRUG: Carboplatin|DRUG: Nab-Paclitaxel|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Cluster Trial on Innovative and Standard Strategies for Neonatal Resuscitation Training (RCPNEOPERU Project)
Status: COMPLETED
Conditions: Neonatal Asphyxia
Interventions: BEHAVIORAL: Standard Neonatal Resuscitation Training|BEHAVIORAL: MP-ICT Neonatal Resuscitation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMS
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Progressive Multiple Sclerosis
Interventions: DRUG: GA Depot 40mg once monthly|DRUG: GA Depot 25mg once monthly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRogression Of bicuSPid-rElated aoRtOpathy in Patients Undergoing Transcatheter Aortic Valve Implantation (PROSPERO-TAVI)
Status: NOT_YET_RECRUITING
Conditions: Bicuspid-related Aortopathy|Aortic Stenosis
Interventions: DIAGNOSTIC_TEST: CT follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Autologous Stem Cells in Pediatric Patients With Dilated Cardiomyopathy
Status: SUSPENDED
Conditions: Cardiomyopathy, Dilated
Interventions: PROCEDURE: Intracoronary autologous stem cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Rechallenge Concept in Patients With BRAF-positive Anaplastic Thyroid Cancer After Progression on Anti-BRAF Therapy
Status: RECRUITING
Conditions: Anaplastic Thyroid Cancer
Interventions: DRUG: Dabrafenib + Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Double-blinding, Parallel and Positive-controlled Phase III Clinical Trial for Efficacy and Safety Evaluation of Ilaprazole Sodium for Injection on Prevention of Stress Ulcer Bleeding
Status: COMPLETED
Conditions: Stress Ulcer Bleeding
Interventions: DRUG: Esomeprazole 40mg|DRUG: Ilaprazole Sodium|DRUG: Placebo 1|DRUG: Placebo 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP)
Status: COMPLETED
Conditions: Hospital-Acquired Pneumonia
Interventions: DRUG: Zavicefta, Ceftazidime-Avibactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Treatment of Intermittent Claudication in Patients With Peripheral Arterial Disease Using Danshen Gegen (D&G) Capsule
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Intermittent Claudication
Interventions: DRUG: Danshen Gegen Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Wound Closure Using a Limberg Flap Versus Secondary Wound Healing Following Pilonidal Sinus Excision
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: secondary wound healing|PROCEDURE: primary wound closure using a limberg flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detrol Long Acting (LA) vs Estrace Vaginal Cream for the Treatment of Overactive Bladder Symptoms
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Extended Release Tolterodine LA|DRUG: Intra Vaginal Estradiol Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bevacizumab and VEGF on Platelet Clustering in Patients Who Are Receiving Bevacizumab for Cancer
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: bevacizumab|OTHER: coagulation study|OTHER: laboratory biomarker analysis|OTHER: platelet aggregation test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Therapy of Antibody-mediated Autoimmune Diseases by Bortezomib (TAVAB)
Status: TERMINATED
Conditions: Myasthenia Gravis|Systemic Lupus Erythematosus|Rheumatoid Arthritis
Interventions: DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Respiratory Syncytial Virus Candidate Encapsulated in a Lipid Nanoparticle Based Formulation in Adults Aged 18 to 50 Years and 60 Years and Older
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Immunization
Interventions: BIOLOGICAL: RSV vaccine candiate formulation 1|BIOLOGICAL: RSV vaccine candidate formulation 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: E-PRISM: Phase II Trial of Elotuzumab Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma
Status: COMPLETED
Conditions: Smoldering Myeloma|Smoldering Multiple Myeloma
Interventions: DRUG: Elotuzumab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablation-Index Guided Ventricular Tachycardia Ablations
Status: NOT_YET_RECRUITING
Conditions: Ventricular Tachycardia|Ventricular Arrythmia|Cardiomyopathies
Interventions: DEVICE: AI-guided VA ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MQX-503 Applied to the Hand Versus Nitroglycerin Ointment Applied to the Chest: A Pharmacokinetic Comparison
Status: COMPLETED
Conditions: Raynaud's Phenomenon
Interventions: DRUG: nitroglycerin 0.9 % (MXQ-503)|DRUG: Nitroglycerin ointment 2%, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Controlled Clinical Trial of Cathodal Transcranial Direct Current Stimulation in Patients With Refractory Epilepsy
Status: COMPLETED
Conditions: Refractory Epilepsy
Interventions: DEVICE: Nicolet Endeavor CR: 30min|DEVICE: Nicolet Endeavor CR: 60min|DEVICE: Nicolet Endeavor CR: 30min for 3 days|DEVICE: Nicolet Endeavor CR: 30min for 5 days|DEVICE: Nicolet Endeavor CR: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of Cardiac Magnetic Resonance Sequences in Patients With Single Ventricles
Status: UNKNOWN
Conditions: Single-ventricle
Interventions: DIAGNOSTIC_TEST: Cardiac Magnetic Resonance Imaging|DIAGNOSTIC_TEST: Blood draw for hematocrit and heart failure biomarkers|DIAGNOSTIC_TEST: Cardiopulmonary exercise test|DIAGNOSTIC_TEST: Exhalomics|DIAGNOSTIC_TEST: Quality of life questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Reducing Surgical Site Infection Rates Using an Alternative Sternal Dressing
Status: RECRUITING
Conditions: Wound of Skin
Interventions: DEVICE: Standard Island Dressing|DEVICE: Prevena Negative Pressure wound dressing|DEVICE: Mepilex Border Post-Op Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib Study of PDR001 in Combination With Regorafenib in Adult Patients With Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: spartalizumab (PDR001)|DRUG: regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Bipolar Disorder|Bipolar Depression|Bipolar I Disorder|Bipolar II Disorder
Interventions: DEVICE: Low Field Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Insulin Resistance|Healthy|Obesity
Interventions: DRUG: Phentolamine|OTHER: Saline|DRUG: Sodium Nitroprusside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-automatic Control of Gait and Posture in Obstructive Sleep Apnea Syndrome (CIH-Gait)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DEVICE: Effective CPAP|DEVICE: Sub-therapeutic CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
Status: RECRUITING
Conditions: Episodic Migraine
Interventions: DRUG: Atogepant|DRUG: Placebo-Matching Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Emotional and Cognitive Factors in Behavioral Weight Loss Treatment (Part 2)
Status: WITHDRAWN
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Standard Behavioral Weight Loss Treatment with Affective and Cognitive Skills Training|BEHAVIORAL: Standard Behavioral Weight Loss Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Research on Effectiveness and Safety of Treatment of Severe Oligospermia or Azoospermia With uFSH
Status: UNKNOWN
Conditions: Oligospermia|Azoospermia
Interventions: DRUG: 75IU uFSH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Digital Twin - Modelling Postprandial Triglyceride and Glucose Responses
Status: COMPLETED
Conditions: Lipid Metabolism|Glucose Metabolism
Interventions: DIAGNOSTIC_TEST: Mixed meal challenge test|DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: DEXA|DEVICE: Freestyle Libre|DEVICE: ActivPAL3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Social ABCs With Attention Training Intervention for Toddlers With Suspected Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Attention Training Program|BEHAVIORAL: Social ABCs|OTHER: Treatment As Usual|BEHAVIORAL: Sham Attention Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors
Status: COMPLETED
Conditions: Glioblastoma|Gliosarcoma|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Anaplastic Mixed Oligoastrocytoma
Interventions: BIOLOGICAL: Bevacizumab|DRUG: MLN-518 (Tandutinib)|PROCEDURE: Quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Medicinal Herbs Treatment on Novel Influenza A (H1N1) : Multi-centre, Prospective, Randomized Controlled Study
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: oseltamivir|OTHER: blank|DRUG: chinese medicinal herbs|DRUG: oseltamivir and chinese medicinal herbs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversion From Unresectable To Resectable Metastatic Colorectal Cancer.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOXIRI and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Evaluation of Platelet Rich Fibrin Matrix (PRFM) for the Correction of Nasolabial Folds
Status: COMPLETED
Conditions: Nasolabial Folds
Interventions: BIOLOGICAL: Platelet rich fibrin matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Clin. Capabilities of LIBERTY® Endovascular Robotic System's Performance & Safety in Periph. Vasc. Interv.
Status: RECRUITING
Conditions: Peripheral Vascular Interventions
Interventions: DEVICE: The LIBERTY® Robotic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya
Status: NOT_YET_RECRUITING
Conditions: Human Immunodeficiency Virus|Human Papillomavirus|Cervical Precancer
Interventions: DRUG: Artesunate vaginal inserts|DRUG: Placebo vaginal inserts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aliskiren and Valsartan vs Valsartan Alone in Patients With Stage II Systolic Hypertension and Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Valsartan|DRUG: Placebo for Aliskiren|DRUG: Placebo for Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hemodilution and Outcome in Cardiac Surgery
Status: TERMINATED
Conditions: Kidney Failure|Intraoperative Complications
Interventions: PROCEDURE: Different timing of red blood cells transfusion (substudy 1); Acute hemodilution versus no hemodilution (substudy 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of Asimadoline, a Member of a New Medication Class, on Acute Attacks of Pain in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: asimadoline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tajik Migrant Health Education Study
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C|Risky Health Behavior|Risk Reduction Behavior
Interventions: BEHAVIORAL: MASLIHAT|BEHAVIORAL: TANSIHAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo / Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Uterus, Ovarian and Reproductive Functions According to Conditioning Regimen and Pubertal Status at the Time of Stem Cell Transplantation in a Leukemia Pediatric Population
Status: UNKNOWN
Conditions: Leukemia
Interventions: OTHER: MRI pelvic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postpartum Uterine Curettage in the Recovery From Preeclampsia/Eclampsia
Status: COMPLETED
Conditions: Pre-Eclampsia|Eclampsia
Interventions: PROCEDURE: Curettage|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia (ALL)
Interventions: DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Surgical Site Infection in Peritonitis After Peritoneal Lavage With Super-oxidixed Solution
Status: NOT_YET_RECRUITING
Conditions: Surgical Site Infection
Interventions: DEVICE: Hydrocyn Aqua®|DEVICE: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Center, Single-Arm Study of Neoadjuvant Short-Course Radiotherapy Concurrent With IL-2 Followed by Sequential Immunotherapy With CAPOX Combined With PD-1 Antibody and IL-2 for Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer|Advanced Solid Tumor
Interventions: DRUG: Sintilimab + IL-2 Combined with Capox|RADIATION: Short-course radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Characterizazion and Biological Samples Centralisation of Patients Affected by Oncoematolofic Pathology
Status: RECRUITING
Conditions: Oncologic Disease|Hematologic Diseases
Interventions: OTHER: Analysis of biological samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5
Status: COMPLETED
Conditions: Kidney Diseases|Metabolic Acidosis|Renal Insufficiency|CKD|Pre-dialysis
Interventions: OTHER: Low PRAL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]
Status: RECRUITING
Conditions: Small Cell Lung Cancers|Neuroendocrine Carcinoma
Interventions: OTHER: No treatment is included in this protocol.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Optimal Dosage for Equivalence Between Lcr Regenerans® Capsules and Tablets (Lactobacillus Rhamnosus Lcr35®) on the Vaginal Flora Colonisation
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal
Interventions: DEVICE: Lcr Regenerans® vaginal capsules|DEVICE: Lcr Regenerans® vaginal tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CONcomitant eValuation of Epicor Left atRial Therapy for AF
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Epicor LP Cardiac Ablation System|PROCEDURE: Surgical ablation of permanent AF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preemie Milk Analyser Validation Study
Status: NOT_YET_RECRUITING
Conditions: Pre-Term|Breast Milk Expression|Nutrition Disorder, Infant
Interventions: DEVICE: Targeted breast milk fortification using preemie device|DIETARY_SUPPLEMENT: Standard Breast milk fortification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Prebiotic Intake on Gut Microbiota in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Prebiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Tox Vs Eox In Patients With Locally Advanced Unresectable Or Metastatic Gastric Cancer
Status: TERMINATED
Conditions: Locally Advanced Unresectable Gastric Cancer|Metastatic Gastric Cancer
Interventions: DRUG: Docetaxel|DRUG: Epirubicin|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Oral vs. Intravenous Acetaminophen
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Oral Acetaminophen|DRUG: Intravenous acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Atrial Fibrillation by Inhibition Conversion Enzyme (ICE) After Radiofrequency Ablation of Atrial Flutter
Status: TERMINATED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: Ramipril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial of Remifentanil Intravenous Patient Controlled Analgesia (PCA) Versus Intramuscular Pethidine for Pain Relief in Labour
Status: COMPLETED
Conditions: Pain Relief in Labour
Interventions: DRUG: Pethidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Functional Scaffold Transplantation Combined With Epidural Electrical Stimulation for Spinal Cord Injury Repair
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DEVICE: Epidural Electrical Stimulation|COMBINATION_PRODUCT: Functional scaffold & Epidural Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia
Status: COMPLETED
Conditions: Lipid Metabolism, Inborn Errors|Hypercholesterolemia, Autosomal Dominant|Hyperlipidemias|Metabolic Diseases|Hyperlipoproteinemia Type II|Metabolism, Inborn Errors|Genetic Diseases, Inborn|Infant, Newborn, Diseases|Metabolic Disorder|Congenital Abnormalities|Hypercholesterolemia|Hyperlipoproteinemias|Dyslipidemias|Lipid Metabolism Disorders
Interventions: DRUG: mipomersen sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With Docetaxel and Gemcitabine in Locally Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Stage II|Breast Cancer Stage III
Interventions: DRUG: docetaxel|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Novel 22-gauge Core Biopsy Needle
Status: COMPLETED
Conditions: Solid Pancreatic Mass Lesions|Malignant Neoplasm of Pancreas
Interventions: DEVICE: Novel 22-gauge Core Biopsy Needle + Standard Biopsy Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fluid Restriction in Patients With Heart Failure
Status: UNKNOWN
Conditions: Heart Failure, Systolic|Heart Failure; With Decompensation|Pulmonary Congestion
Interventions: BEHAVIORAL: Fluid restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Therapy and SPECT Brain Imaging in Cerebral Decompression Illness
Status: UNKNOWN
Conditions: Cerebral Decompression Illness, All Phases
Interventions: DRUG: Hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of JR-131 in Renal Anemia Patients With Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: JR-131|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Sodium-glucose Linked Transporter 2 (SGLT-2) Inhibitors in Recurrent Ascites: a Pilot RCT
Status: UNKNOWN
Conditions: Cirrhosis|Ascites Hepatic
Interventions: DRUG: Dapagliflozin (10Mg Tab) along with standard medical therapy|DRUG: Placebo of dapaglifozin along with standard medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Autologous PRP Infusion Compared to HRT for Enhancing Endometrial Thickness in Patients Undergoing ICSI
Status: UNKNOWN
Conditions: Infertility
Interventions: BIOLOGICAL: platlet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confirm Safety and Performance of Avance Solo and Avance Solo Adapt NPWT Systems
Status: COMPLETED
Conditions: Venous Leg Ulcer|Pressure Ulcer|Diabetic Foot Ulcer|Chronic Ulcer
Interventions: DEVICE: Avance Solo NPWT System|DEVICE: Avance Solo Adapt NPWT System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Untreated or Transformed Follicular Non-Hodgkin's Lymphoma With Fission-Derived Iodine I 131 Tositumomab
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Iodine I 131 Tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Binodenoson in Assessing Cardiac Ischemia
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: binodenoson|DRUG: adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Gradual Withdrawal of Immune System Suppressing Drugs in Patients Receiving a Liver Transplant
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C, Chronic|Nonimmune Nonviral Causes of Liver Failure
Interventions: DRUG: calcineurin inhibitor-based immunosuppression|PROCEDURE: liver transplant|DRUG: corticosteroids|OTHER: immunosuppression withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Treatment of Multiple Erythema Migrans
Status: UNKNOWN
Conditions: Multiple Erythema Migrans
Interventions: DRUG: ceftriaxone|DRUG: doxycycline|OTHER: erythema migrans patients treated with doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Accuracy of Transperineal Ultrasound (TPUS) Versus Magnetic Resonance Imaging (MRI) for the Assessment of Perianal Fistulae in Patients With Crohn's Disease (CD): a Prospective Observational Longitudinal Cohort Study
Status: RECRUITING
Conditions: Crohn Disease|Perianal Fistula
Interventions: OTHER: A multicentric prospective observational longitudinal cohort study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls
Status: COMPLETED
Conditions: Type 2 Diabetes and Exercise
Interventions: OTHER: 45 minutes of moderate exercise at the fasted state. Before test day 2: 3 days of carbohydrate loading.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pedometer Based Intervention After Total Hip Replacement-A Pilot Study
Status: COMPLETED
Conditions: Osteoarthritis of Hip
Interventions: PROCEDURE: Targetted protocol with pedometer|DEVICE: Accelerometer(ActivPAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Alcohol Use & Post-traumatic Stress Disorder (PTSD) With Cognitive Restructuring & Experiential Acceptance
Status: COMPLETED
Conditions: Alcoholism|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Experiential acceptance|BEHAVIORAL: Cognitive restructuring|OTHER: No-intervention control: Nutrition information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Non-ablative in the Treatment of Genitourinary Syndrome of Menopause
Status: RECRUITING
Conditions: Genitourinary Syndrome of Menopause
Interventions: DEVICE: Radiofrequency non ablative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites
Status: COMPLETED
Conditions: Wound Closure Technique
Interventions: DEVICE: Polyglactin 910 sterile synthetic absorbable suture (Ethicon)|DEVICE: Chromic Gut Sterile absorbable Suture (Ethicon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis
Status: UNKNOWN
Conditions: Chorioretinitis
Interventions: DRUG: pyrimethamine-sulfadiazine + prednisolone|DRUG: Clindamycin+Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Efficacy and Safety of Subetta in the Combined Treatment of Patients With Type I Diabetes Mellitus
Status: COMPLETED
Conditions: Type I Diabetes Mellitus
Interventions: DRUG: Subetta|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Paclitaxel in Combination With BOS172722 in Patients With Advanced Nonhaematologic Malignancies
Status: COMPLETED
Conditions: Advanced Nonhaematologic Malignancies
Interventions: DRUG: BOS172722|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Pulsed Infusions of Levosimendan in Outpatients With Advanced Heart Failure
Status: UNKNOWN
Conditions: Chronic Stable Heart Failure
Interventions: DRUG: Levosimendan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of CPX-351 in Adult Patients With First Relapse Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: CPX-351|DRUG: Intensive Salvage Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assesment of the Accuracy of Surgical Guide Designed From CBCT With Different Voxel Sizes
Status: UNKNOWN
Conditions: Accuracy of Surgical Guide in Implants
Interventions: OTHER: Surgical guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Remote Ischemic Preconditioning in Aortic Valve Replacement Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Cardiopulmonary Bypass
Interventions: PROCEDURE: Blood pressure cuff inflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Restrictive Fluid Strategy on Postoperative Oliguric Pancreatic Surgery Patients
Status: TERMINATED
Conditions: Fluid Therapy|Postoperative Period|Postoperative Complications|Pancreas Disease|Fluid Overload
Interventions: DRUG: Ringer's Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Remimazolam Tosilate for Sedation in the ICU
Status: COMPLETED
Conditions: Sedation in the ICU
Interventions: DRUG: Remimazolam Tosilate|DRUG: Propofol Medium and Long Chain Fat Emulsion Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Added to Propofol for Drug Induced Sleep Endoscopy
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bmgim Music Therapy Method in Reducing Stress in Patients With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Bowel Diseases, Inflammatory|Crohn Disease|Colitis, Ulcerative
Interventions: OTHER: BMGIM Music Therapy Method
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low Intensity Ultrasound Therapy for Upper Back Pain Relief
Status: COMPLETED
Conditions: Muscle Spasm
Interventions: DEVICE: Active ultrasound therapy device|DEVICE: Placebo ultrasound therapy device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries
Status: RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy|Birth Asphyxia
Interventions: OTHER: Umbilical cord milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Of CP-195543 And Celecoxib Dual Therapy In Subjects With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CP-195,543|DRUG: celecoxib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Add on Study in Japan
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Linagliptin|DRUG: Linagliptin|DRUG: Metformin|DRUG: Metformin|DRUG: Linagliptin|DRUG: Linagliptin|DRUG: Linagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Paraesophageal Lymph Node Metastasis Versus Supraclavicular Lymph Node Metastasis on the Overall Survival of Patients With Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study
Status: COMPLETED
Conditions: Esophageal Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of an Intrauterine Contraceptive Device (IUD) in HIV Infected Women
Status: COMPLETED
Conditions: HIV Infections
Interventions: DEVICE: Levonorgestrel-releasing intrauterine device (IUD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficiency of Physiotherapeutic Care in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: OTHER: ParkNet|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypertonic Saline as Therapy for Pediatric Concussion
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Hypertonic Saline|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders|Metabolic Disease|Endocrine System Diseases
Interventions: DRUG: DWP16001|DRUG: Dapagliflozin|DRUG: DWP16001 Placebo|DRUG: Dapagliflozin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose of HL237 in Healthy Male Subject
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: HL237|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER