pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS
Status: COMPLETED
Conditions: Prone Positioning|High Flow Nasal Cannula|Acute Respiratory Distress Syndrome|Corona Virus Infection
Interventions: DEVICE: high flow nasal cannula (HFNC)|PROCEDURE: Prone positioning (PP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Health Application on Posttraumatic Growth in Women Diagnosed With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Posttraumatic Growth|Grief
Interventions: OTHER: Mobile health application use|OTHER: Information of the breast cancer survivor period booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infiltration Analgesia After Caesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative|Caesarean Section
Interventions: DRUG: Ropivacaine 0,75%|DRUG: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TLA in Children With Moderate to Severe Atopic Eczema (TLA4AE)
Status: RECRUITING
Conditions: Atopic Dermatitis Eczema
Interventions: DEVICE: Nocturnal Temperature controlled Laminar Airflow (TLA) Treatment|DEVICE: Placebo TLA Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retifanlimab With Bevacizumab and Hypofractionated Radiotherapy for the Treatment of Recurrent Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Recurrent Glioblastoma|Recurrent WHO Grade 4 Glioma
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Electronic Health Record Review|RADIATION: Hypofractionated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Retifanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Finding Study of CpG in Patients With Chronic Lymphocytic Leukemia Who Have Been Previously Treated
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: CpG 7909
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoantigen DNA Vaccine in Pancreatic Cancer Patients Following Surgical Resection and Adjuvant Chemotherapy
Status: TERMINATED
Conditions: Pancreatic Cancer|Pancreas Cancer|Cancer of the Pancreas
Interventions: BIOLOGICAL: Personalized neoantigen DNA vaccine|DEVICE: TDS-IM Electrode Array System|PROCEDURE: Peripheral blood draws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LOL: It's All Improv After Cancer! The Impact of Improvisational Comedy on Well-Being Among Patients With Cancer
Status: COMPLETED
Conditions: Distress|Breast Neoplasms|Quality of Life
Interventions: BEHAVIORAL: Improvisational Comedy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multi-center, Prospective, Randomized Study With PriMatrix and PriMatrix Ag for the Treatment of Venous Leg Ulcers
Status: TERMINATED
Conditions: Venous Stasis Ulcer
Interventions: DEVICE: PriMatrix|DEVICE: PriMatrix Ag|PROCEDURE: moist wound therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Assess Steviol Glycosides on Acute Appetite Hormone Release
Status: ENROLLING_BY_INVITATION
Conditions: Overweight and Obesity|Type 2 Diabetes Mellitus
Interventions: OTHER: Water|OTHER: Glucose|OTHER: Steviol Glycosides|OTHER: Steviol Glycosides plus glucose|OTHER: Rebaudioside A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Glioma
Interventions: DRUG: Abemaciclib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Growth in Children With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: tacrolimus ointment 0.1%|DRUG: mometasone furoate 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose:
Clinical trial: Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Combat Disorders|Sleep Disorders
Interventions: DRUG: prazosin hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between the Caudal Block and Other Methods of Postoperative Pain Relief in Children Undergoing Circumcision
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative|Pain, Acute
Interventions: PROCEDURE: caudal block|PROCEDURE: Dorsal Penile Nerve Block DPNB|DRUG: Systemic opioids
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Management of Preoperative Anaemia in Surgical Oncology
Status: UNKNOWN
Conditions: Anemia|Tumor
Interventions: DRUG: Ferric Carboxymaltose Injection|DRUG: Folic acid|DRUG: B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegaspargase-COEP Chemotherapy Combined With Radiotherapy for Extra-nodal NK/T Cell Lymphoma
Status: RECRUITING
Conditions: NK/T Cell Lymphoma Nos
Interventions: DRUG: pegaspargase, cyclophosphamide, vincristine, etoposide, prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: AGN-199201|DRUG: AGN-190584|DRUG: AGN-199201 Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Individually-Marked Panretinal Laser phoTocoagulation for Proliferative Diabetic Retinopathy Study (TREAT)
Status: COMPLETED
Conditions: Proliferative Diabetic Retinopathy|PDR|Diabetes
Interventions: PROCEDURE: Panretinal Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Physical Exercise on Pulmonary Ventilation and Recruitment
Status: COMPLETED
Conditions: Critical Illness
Interventions: OTHER: A: Chair - Leg Cycle ergometer|OTHER: B: Chair - Arm Cycle ergometer|OTHER: C: Walk in place
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: Semaglutide|DRUG: Semaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fecal Filtrate as a Treatment Option of Multiple Recurrent Clostridioides Difficile Infection
Status: NOT_YET_RECRUITING
Conditions: Clostridium Difficile Infection|Recurrent Clostridium Difficile Infection
Interventions: BIOLOGICAL: Fecal filtrate transplantation|BIOLOGICAL: Conventional fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abraxane, Avastin, and Gemcitabine as First-Line Therapy for Patients With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Avastin|DRUG: Gemcitabine|DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Bevacizumab-IRDye800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intermittent Imatinib Treatment in Chronic Myeloid Leukemia and Philadelphia Chromosome (Ph+CML) Patients Who Achieved a Complete Cytogenetic Response (CCgR) on Standard Imatinib Therapy
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propranolol for Sleep Apnea Therapy
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Propranolol Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Enhanced Recovery in Pancreaticoduodenectomy
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: BEHAVIORAL: Enhanced recovery after surgery protocol|PROCEDURE: Standard perioperative care|DRUG: PONV prophylaxis with Ondansetron + Dexamethasone|OTHER: Postoperative mobilization program|DRUG: Epidural analgesia with naropin + sufentanil|DRUG: Pre-anesthetic medication with diazepam|BEHAVIORAL: Preadmission counselling|DRUG: Preoperative bowel preparation with sodium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Esomeprazole, Moxifloxacin and Amoxicilin for Rescue Therapy of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection|Chronic Gastritis
Interventions: DRUG: esomeprazole|DRUG: moxifloxacin|DRUG: amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial of TQB2102 for Injection Against Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: TQB2102 for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Anti-HPA Antibodies Caused Neonatal Alloimmune Thrombocytopenia in Chinese Pregnant Women
Status: UNKNOWN
Conditions: Neonatal Alloimmune Thrombocytopenia
Interventions: PROCEDURE: Standard clinical treatment, including intravenous immunoglobulin and/or platelet transfusion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trastuzumab Deruxtecan Versus Standard Neoadjuvant Treatment for HER2-positive Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab deruxtecan|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Ribociclib|DRUG: Letrozole|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Ureteral Stent Symptoms - a Comparison to Standard Ureteral Stent as Perceived By the Patient (MAGUSS)
Status: UNKNOWN
Conditions: Urinary Tract Stone|Kidney Stone
Interventions: PROCEDURE: ureteral double-J stent removal using magnet|PROCEDURE: ureteral double-J stent removal using cystoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise or Vibration With HMB for Sarcopenia
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Hydroxymethylbutyrate|DEVICE: Low-magnitude High Frequency Vibration (LMHFV)|BEHAVIORAL: Elastic-band Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Comparison of Advate rAHF-PFM With Recombinate rAHF in Patients With Severe Hemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: Antihemophilic Factor (Recombinant) - Plasma/Albumin Free Method (rAHF-PFM)|DRUG: Recombinant Factor VIII (rAHF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Person-centred Support for Women After Treatment for Gynaecological Cancer
Status: COMPLETED
Conditions: Malignant Female Reproductive System Neoplasm|Follow-up|Supportive Care|Psychosocial Circumstances|Survivorship
Interventions: BEHAVIORAL: Autonomy supportive counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study on BP1.4979 Effect on Binge Eating Disorders
Status: RECRUITING
Conditions: Binge-Eating Disorder
Interventions: DRUG: BP1.4979 active drug|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Enteric-coated Mycophenolate Sodium (EC-MPS) With Cyclosporine Microemulsion and Steroids in Pediatric de Novo Renal Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessing the Hemostatic Efficacy of Pathogen Reduced Platelets in Children Undergoing Cardiopulmonary Bypass Surgery: A Pilot Clinical Trial
Status: TERMINATED
Conditions: Cardiopulmonary Bypass Surgery
Interventions: BIOLOGICAL: Platelet Transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Imaging, Blood, and Tissue Samples to Guide Treatment of Colon Cancer and Related Liver Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer|Liver Tumors
Interventions: OTHER: blood draws|PROCEDURE: colectomy or hepatectomy|DIAGNOSTIC_TEST: Fibroscan test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BE Smart - Bariatric Patient - Empowerment in the Preparation and Follow-up of Bariatric Surgery Using the Smartvisit App (BESmart)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: DEVICE: smart visit app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Budesonide as an Addition to Standard Therapy in Adult Asthmatics in the Emergency Room.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide|DRUG: albuterol|DRUG: Ipratropium bromide|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Protocols to Prevent the Acquisition of Methicillin-Resistant Staphylococcus Aureus.
Status: COMPLETED
Conditions: Nosocomial Infections|MRSA Colonization
Interventions: PROCEDURE: Reinforced isolation + Muciprocine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 and Extensional Study of Besifovir
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: besifovir 150mg|DRUG: tenofovir 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Tamsulosin in the Prevention of Post-operative Urinary Retention in Men After Rectum Resection
Status: NOT_YET_RECRUITING
Conditions: Urinary Retention|Colorectal Surgery|Rectal Resection|Post-operative Urinary Retention|Tamsulosin
Interventions: DRUG: pr Sandoz Tamsulosin|DRUG: Glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Compare the Pharmacokinetics and Safety of D113 With CKD-349 in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Renal Failure
Interventions: DRUG: CKD-349 F1 Tab.|DRUG: CKD-349 F2 Tab.|DRUG: D113 Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Clostridium Difficile Infection
Interventions: DRUG: Vancomycin|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alendronate Sodium 70 mg Tablet Versus Fosamax® Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Alendronate Sodium Tablets 70mg|DRUG: Fosamax® Tablets 70mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Brain Areas of Time-To-Contact Perception: an Awake Surgery Study
Status: RECRUITING
Conditions: Brain Tumors
Interventions: BEHAVIORAL: Behavioral task|PROCEDURE: Awake surgery|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment|OTHER: Neurological assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of BLIS K12 as Preventive Measure for Rheumatic Children
Status: UNKNOWN
Conditions: Rheumatic Fever
Interventions: DIETARY_SUPPLEMENT: Streptococcus Salivarius BLIS K12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Early Percutaneous Catheter Drainage of Sterile Pancreatic Fluid Collections in Severe Acute Pancreatitis
Status: UNKNOWN
Conditions: Severe Acute Pancreatitis
Interventions: DEVICE: Puncture and drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Alemtuzumab for Consolidation and Maintenance of Patients With B-Cell Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRescribing INterventions for Chronic Pain Via the Electronic Health Record Study - Primary Care Providers
Status: COMPLETED
Conditions: Opioid-use Disorder|Opioid Use|Opioid Abuse
Interventions: BEHAVIORAL: Choice Architecture Nudge|BEHAVIORAL: PMP Integration & Nudge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Vaginal Intraepithelial Neoplasia|Vulvar Intraepithelial Neoplasia|Persistent Infection
Interventions: BIOLOGICAL: HPV Vaccine|BIOLOGICAL: HEV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: My Scrivener® - Measuring Effectiveness and Dose Response in Children
Status: COMPLETED
Conditions: Asperger's Syndrome|Dyslexia|Cerebral Palsy|Attention Deficit Disorder|ADHD|Traumatic Brain Injury|Stroke
Interventions: DEVICE: My Scrivener(R)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Autologous Bone Marrow-Derived Mononuclear Stem Cells (BM-MNC) and Liberation Therapy (When Associated With CCSVI) in Patients With RRMS
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: BIOLOGICAL: Autologous Bone Marrow-Derived Mononuclear Stem Cells|OTHER: Liberation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Lixisenatide (AVE0010)|DRUG: Placebo|DRUG: Antidiabetic background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Secondary Beneficial Effects of Prostaglandin Analog Treatment in Thyroid Eye Disease Patients.
Status: WITHDRAWN
Conditions: Thyroid Eye Disease|Ocular Hypertension|Glaucoma
Interventions: DRUG: Prostaglandin Analog|DRUG: Timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma Stage II|Esophageal Squamous Cell Carcinoma Stage III
Interventions: PROCEDURE: Neoadjuvant Chemoradiotherapy|DRUG: Tislelizumab|PROCEDURE: Ivor-Lewis or Mckeown Esophagectomy(Mckeown Esophagectomy recommended)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Asthma|Chronic Rhinosinusitis Without Nasal Polyps
Interventions: BIOLOGICAL: Mepolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Cervical Neoplasms|Endometrial Neoplasms|Squamous Cell Carcinoma of Head and Neck|Gallbladder Neoplasms|Cholangiocarcinoma|Esophageal Neoplasms|Triple Negative Breast Neoplasms|Hepatocellular Carcinoma|Urinary Bladder Neoplasms|Ovarian Neoplasms|Stomach Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab/Vibostolimab Co-Formulation|BIOLOGICAL: Pembrolizumab|DRUG: Lenvatinib|DRUG: 5-Fluorouracil|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Bevacizumab|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Albuterol DPI (A006) Clinical Study-B3:Efficacy, Dose-ranging and Safety Evaluation
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: A006 DPI|DRUG: A006 DPI|OTHER: Placebo DPI|DRUG: Proventil® MDI|DRUG: Proventil® MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms|Chemoradiotherapy|Stomatitis and Ulceration
Interventions: DRUG: Herbal gargle|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of CMV Towne Vaccine in Subjects Previously Received VCL CT02 Vaccine ID or IM
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: BIOLOGICAL: Towne CMV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Influences of Angiotensin-neprilysin Inhibition on Sympathetic Activity in Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: COMBINATION_PRODUCT: sacubitril+valsartan|DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Eating Behaviour and Gustatory Sensitivity Before and After Liver Transplant in Cirrhotic Patients
Status: COMPLETED
Conditions: Eating Behaviour|Liver Transplant
Interventions: OTHER: Respiratory quotient|OTHER: Olfactory liking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: National Registry of Adult Heart Failure Patients With Complex Congenital Heart Disease: Systemic Right Ventricle and Single Ventricle Treated With Sacubitril/Valsartan
Status: RECRUITING
Conditions: Complex Congenital Heart Disease
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Pharmacokinetic Evaluations of CKR-051 After Transdermal Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CKR-051 Dose 1|DRUG: CKR-051 Dose 2|DRUG: CKR-051 Dose 3|DRUG: CKR-051 Dose 4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABP-671 in Healthy Subjects
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: ABP-671|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Public Health Emergency: SOLIDARITY TRIAL Philippines
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Remdesivir|DRUG: Hydroxychloroquine|DRUG: Lopinavir / Ritonavir|DRUG: Interferon beta-1a|DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Guarantee Assessment in Skin Prevention Adapted to Real Life With a Connected Device After a Spinal Cord Injury."
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injury
Interventions: DEVICE: GASPARD®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of LCZ696 Compared to Valsartan on Cognitive Function in Patients With Chronic Heart Failure and Preserved Ejection Fraction
Status: COMPLETED
Conditions: Chronic Heart Failure (CHF)
Interventions: DRUG: LCZ696|DRUG: Valsartan|DRUG: Placebo of LCZ696|DRUG: Placebo of Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation Study of Multiple Probe Compounds for Drug Interaction Evaluation
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: Caffeine|DRUG: Rosiglitazone|DRUG: Flurbiprofen|DRUG: Omeprazole|DRUG: Dextromethorphan|DRUG: Midazolam|DRUG: Rosuvastatin|DRUG: Ketoconazole|DRUG: Fluconazole|DRUG: Rifampin|DRUG: Rosiglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hyaluronic Acid Injection in the Glans Penis Versus Selective Serotonin Reuptake Inhibitors for Lifelong Premature
Status: COMPLETED
Conditions: Selective Serotonin Reuptake Inhibitor|Hyaluronic Acid|Glans Penis|Lifelong Premature
Interventions: DRUG: Selective serotonin re-uptake inhibitor|DRUG: Hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients
Status: RECRUITING
Conditions: Immunization; Infection|Transplantation Infection|Influenza|Solid Organ Transplant
Interventions: BIOLOGICAL: High Dose Quadrivalent Inactivated Influenza Vaccine|BIOLOGICAL: Standard Dose Quadrivalent Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months
Status: ACTIVE_NOT_RECRUITING
Conditions: Jaw, Edentulous
Interventions: PROCEDURE: Re-Entry Surgery|PROCEDURE: Probing peri-implant bone|PROCEDURE: Scanning peri-implant bone|PROCEDURE: Conventional Impressions|PROCEDURE: Implant Surgery|PROCEDURE: Healing procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of BAY1067197 in Stable Heart Failure Patients on Standard Therapy Including ß-blocker
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Placebo (treatment 1)|DRUG: BAY1067197 (treatment 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasonic Explorations of Cerebral Tissue Motions - Influence of Aging
Status: COMPLETED
Conditions: Aging|Cerebral Pulsatility
Interventions: DEVICE: Fast Cerebral Pulsatility Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: DHEA Bioavailability Following Administration of Vaginal Suppositories in Post-Menopausal Women With Vaginal Atrophy
Status: COMPLETED
Conditions: Vaginal Atrophy
Interventions: DRUG: DHEA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Goal Directed Fluid Management in Supratentorial Brain Tumor Craniotomy
Status: COMPLETED
Conditions: Brain Tumor|Craniotomy
Interventions: PROCEDURE: Pulse pressure variation guided fluid therapy|PROCEDURE: Traditional fluid therapy|PROCEDURE: Brain tumor excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral CF101 Tablets Treatment in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CF101|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study Comparing 2 Brain Conformational Radiotherapy in Combination With Chemotherapy in the Treatment of Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: RADIATION: Radiotherapy|RADIATION: Experimental arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the Management of Periodontal Patients
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: OTHER: Aftoral Oral gel|OTHER: Unidea Chlorhexidine digluconate mouthwash 0.20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety and Tolerability of CSL730 in Healthy Caucasian and Japanese Adults
Status: TERMINATED
Conditions: Healthy
Interventions: BIOLOGICAL: CSL730|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of an Inter-Disciplinary Program, Including MBSR, in Breast Cancer Survivors With Chronic Neuropathic Pain
Status: COMPLETED
Conditions: Breast Cancer|Painful Neuropathy|Chronic Pain|Worries; Pain or Disability|Quality of Life
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ospemifene vs. Conjugated Estrogens in the Treatment of Postmenopausal Sexual Dysfunction
Status: TERMINATED
Conditions: Sexual Dysfunction, Physiological
Interventions: DRUG: Ospemifene|DRUG: Vaginal conjugated estrogens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 595 First-in-Human in Recurrent Gliomas
Status: COMPLETED
Conditions: Advanced Malignant Glioma|Anaplastic Astrocytomas|Glioblastoma Multiforme
Interventions: DRUG: AMG 595
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromagnetic Navigational Bronchoscopy Vs. Transthoracic Needle Biopsy for the Sampling of Peripheral Lung Nodules
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: Electromagnetic Navigation Bronchoscopy|PROCEDURE: Transthoracic Needle Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Trial of Medi-Cal Beneficiaries Calling the California Smokers' Helpline
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Telephone counseling|DRUG: Nicotine patches|BEHAVIORAL: Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Point-of-Care Ultrasound
Status: UNKNOWN
Conditions: Anesthesia|Ultrasound|Emergencies|Operation|Ultrasonography|Surgery
Interventions: DIAGNOSTIC_TEST: Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I-II Study on Treatment of Advanced Oropharynx Cancer in Elderly Population by Intensity Modulated Radiotherapy With Treatment Volume Reduction and Combination Chemotherapy
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: RADIATION: Modulated radiotherapy (IMRT) using RapidArc® or Helical Tomotherapy® at a dose of 70 Gy in 33 fractions to the PTV (GTV) and 59.4 Gy in 33 fractions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Cellcept and Avonex as Combination Treatment in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Mycophenolate Mofetil (CellCept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tuberculosis Preventive Therapy Among Latent Tuberculosis Infection in HIV-infected Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV-infected Participants With Latent TB Infection in High TB Burden Country
Interventions: DRUG: Isoniazid/Rifapentine daily (4 weeks) plus pyridoxine (vitamin B6)|DRUG: Isoniazid/Rifapentine 12-weekly plus pyridoxine (vitamin B6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Immune Killer Cells to Treat Liver Cancer Patients as an Adjunct Therapy
Status: UNKNOWN
Conditions: HepatoCellular Carcinoma|Liver Cancer
Interventions: BIOLOGICAL: IKC (Immune Killer Cells)|PROCEDURE: TACE (Transcatheter Arterial Chemoembolization)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Liraglutide in Subjects With Impaired Kidney Function and in Subjects With Normal Kidney Function
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study to Evaluate Clearance of Superficial Basal Cell Carcinoma After Use of Imiquimod 5% Cream
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: Imiquimod 5% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Passive Mobilization in Patients With Subacromial Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement
Interventions: OTHER: Specific passive mobilization|OTHER: Standardized treatment (standard protocol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Neurally Adjusted Ventilatory Assist (NAVA) Versus Pressure Support During Asynchrony in Children
Status: UNKNOWN
Conditions: Patient/Ventilator Asynchrony
Interventions: OTHER: Pressure Support Ventilation|OTHER: Neurally adjusted ventilatory assist (NAVA)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: cytarabine|DRUG: decitabine|DRUG: doxorubicin hydrochloride|DRUG: imatinib mesylate|DRUG: methotrexate|DRUG: pegaspargase|DRUG: prednisone|DRUG: vincristine sulfate|DRUG: vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Tibial Nerve Block vs Local Infiltration Analgesia After Prothetic Knee Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Knee Osteoarthritis
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Ropivacaine 0.2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Niraparib Maintenance Treatment in mCRC With a Partial o Complete Response After Oxaliplatin-based Induction Therapy
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: Lete-cel|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Micro-dose and Low-dose Recombinant Human Erythropoietin on Mitochondrial Function and Cognitive Performance
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DRUG: Low-dose rhEpo|DRUG: Micro-dose rhEpo|OTHER: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Noninvasive Positive Pressure Ventilation Using Helium:Oxygen Versus Air:Oxygen in Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients Exposed to Sulfur Mustard
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Bronchiolitis
Interventions: DRUG: helium:oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Infliximab|DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Amitriptyline for Painful Bladder Syndrome (PBS)
Status: COMPLETED
Conditions: Bladder Diseases|Interstitial Cystitis
Interventions: DRUG: Amitriptyline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Qishenyiqi Dripping Pills for Treating Chronic Heart Failure With Preserved Ejection Fraction
Status: RECRUITING
Conditions: Chronic Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Qishen Yiqi dripping pills 2 bags/time + Qishen Yiqi dripping pills placebo 2 bags/time|DRUG: Qishen Yiqi dripping pills 4 bags/time|DRUG: Qishen Yiqi dripping pills placebo 4 bags/time
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Effect of Different Supplements on Fluid and Sodium Status in Short Bowel
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Vital 1.5|DIETARY_SUPPLEMENT: Ensure Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
Status: RECRUITING
Conditions: Depression|Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a LRC™ (L. Reuteri NCIMB 30242) Capsule on Managing Cholesterol in Adults
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: LRC™ capsule|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of Neuromuscular Electrical Stimulation and Mirror Therapy in Hemiplegia Rehabilitation
Status: UNKNOWN
Conditions: Hemiplegia|Upper Extremity Dysfunction
Interventions: OTHER: Group Mirror|DEVICE: Group NMES|OTHER: Group Mirror+NMES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synergistic Innovative Functional Food Concepts to Neutralize Inflammation for Cardiometabolic Risk Prevention
Status: COMPLETED
Conditions: Cardiometabolic Risk|Abdominal Obesity
Interventions: OTHER: bioactive components fortified food products intake (biscuits and cookies)|OTHER: control food products intake (biscuits and cookies)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Donor-Derived Viral Specific T-cells (VSTs) for Prophylaxis Against Viral Infections After Allogeneic Stem Cell Transplant
Status: COMPLETED
Conditions: Allogeneic Stem Cell Transplant|Viral Infection
Interventions: BIOLOGICAL: Viral Specific T-cells (VSTs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cetuximab Maintenance Treatment Versus Continuation After Induction Therapy in mCRC
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: mFOLFOX6|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects
Status: COMPLETED
Conditions: Alzheimer Disease|Huntington Disease
Interventions: DRUG: digoxin|DRUG: digoxin|DRUG: dimebon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yoghurt Consumption, Body Weight Management and Glycemic Control of T2DM Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Plain yoghurt|OTHER: Vitamin B yoghurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT