pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
Status: UNKNOWN
Conditions: Lung Cancer|Malnutrition|Nutritional Deficiency
Interventions: DIAGNOSTIC_TEST: Nutritional Risk Screening-2002|DIAGNOSTIC_TEST: Nutritional Risk Index|DIAGNOSTIC_TEST: Mini Nutritional Assessment|DIAGNOSTIC_TEST: Glasgow Prognostic Score|DIAGNOSTIC_TEST: Prognostic Nutritional Index|DIAGNOSTIC_TEST: Anthropometric measurements|DEVICE: Handgrip strength test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer
Status: RECRUITING
Conditions: Advanced Cancer|Metastatic Solid Tumor
Interventions: DRUG: BC3195
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Prednisolone in a Modified Conjunctival Allergen Challenge Model
Status: COMPLETED
Conditions: Chronic Allergic Conjunctivitis
Interventions: DRUG: Prednisolone Sodium Phosphate Ophthalmic Solution 1%|DRUG: Tears Naturale II Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Short Versus Standard of Care Antibiotic Duration for Children Hospitalized for CAP
Status: NOT_YET_RECRUITING
Conditions: Community Acquired Pneumonia in Children
Interventions: DRUG: Ampicillin for Injection|DRUG: Ceftriaxone for Injection|DRUG: Amoxicillin|DRUG: Ampicillin / Sulbactam Injection|DRUG: Amoxicillin-clavulanate|DRUG: Clindamycin|DRUG: Cefprozil|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab With IVAC Salvage Chemotherapy in Diffuse Large B Cell Lymphoma Patients
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Ofatumumab|DRUG: Etoposide|DRUG: Ifosfamid|DRUG: Mesna|DRUG: Cytarabine|DRUG: Methotrexate|DRUG: Leukovorin|DRUG: Granulocyte-Colony Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Impact of Nocturnal Hypoglycaemia on Sleep in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: OTHER: glucose clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: VB-111 in Surgically Accessible Recurrent/Progressive GBM
Status: TERMINATED
Conditions: Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: VB11|PROCEDURE: Surgery|OTHER: Placebo|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Five Different Methods Of Delivering A Lifestyle Modification Program for Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Face-to-face counseling by a dietitian (months 1-3: weekly, months 4-6: every other week)|BEHAVIORAL: Face-to-face counseling by a dietitian (monthly)|BEHAVIORAL: Counseling by a dietitian via telephone (months 1-3: weekly, months 4-6: every other week)|BEHAVIORAL: Counseling by a dietitian via e-mail (months 1-3: weekly, months 4-6: every other week)|BEHAVIORAL: Self help
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care
Status: COMPLETED
Conditions: Alzheimer Disease, Late Onset|Stroke|Heart Failure|Pulmonary Disease, Chronic Obstructive|Cystic Fibrosis Pulmonary Exacerbation|Chronic Liver Disease and Cirrhosis|Kidney Failure, Acute|Kidney Failure, Chronic
Interventions: OTHER: Health Education Manual|OTHER: manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions
Status: COMPLETED
Conditions: Knee Injuries|Cartilage Injury|Osteochondral Defect
Interventions: PROCEDURE: Biomaterials augmented with mesenchymal stem/stromal cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RFA Using Gradual RF Energy Delivery Mode With Octopus Electrodes
Status: UNKNOWN
Conditions: Radiofrequency Ablation|Carcinoma, Hepatocellular
Interventions: PROCEDURE: RFA using gradual RF energy delivery mode with Octopus electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taste Assessment Study of 2 Atazanavir Powder Formulations in Healthy Subjects
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atazanavir (current formulation)|DRUG: Atazanavir, powder for oral use 1 (POU1)|DRUG: Atazanavir (POU2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of NSI-189 for Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: 80 Milligrams NSI-189|DRUG: Placebo|DRUG: 40 Milligrams NSI-189
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Growth Factor (OGF) and Gemcitabine: Novel Treatment for Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|BIOLOGICAL: Opioid Growth Factor (OGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brief Admission by Self-referral for Individuals With Self-harm: Effects on Compulsory Care
Status: RECRUITING
Conditions: Self-injury|Suicide|Suicide, Attempted|Self-harm|Borderline Personality Disorder|Emergency Psychiatric|Hospitalizations Psychiatric
Interventions: OTHER: Brief Admission by self-referral (BA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Monitoring of Systemic or Organ Perfusion for Preterm Infants
Status: COMPLETED
Conditions: Infant, Premature|Hypoperfusion in Newborn|Necrotizing Enterocolitis of Newborn|Sepsis Newborn|Oliguria|Hypotension
Interventions: DEVICE: NIRS (near Infra-red spectroscopy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Manipulation and Myofascial Techniques On Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Manipulation, Psychologic|Pain|Performance Anxiety|Participation, Patient|Physiotherapists
Interventions: OTHER: Comparing to Manipulation and Myofascial Release Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effect of ASP1585 on Pharmacokinetics of Valsartan in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy|Pharmacokinetics of Valsartan
Interventions: DRUG: ASP1585|DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Priming Effects of Ultra-high Frequency Quattro Pulse Transcranial Brain Stimulation Prior to Hand Motor Function Training in Children With Unilateral Spastic Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy, Spastic|Transcranial Magnetic Stimulation, Repetitive
Interventions: OTHER: Quadri-pulse theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
Status: RECRUITING
Conditions: Cystic Fibrosis|Pancreatic Insufficiency|Abnormal Glucose Tolerance|Diabetes
Interventions: DRUG: Dulaglutide 0.75Mg/0.5Ml Inj Pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Topical Mitomycin C for Complex Benign Esophageal Anastomotic Strictures
Status: WITHDRAWN
Conditions: Esophageal Stenosis|Anastomotic Stenosis
Interventions: DRUG: Mitomycin C|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of Aducanumab (BIIB037) (Recombinant, Fully Human Anti-Aβ IgG1 mAb) in Participants With Prodromal or Mild Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Aducanumab (recombinant, fully human anti-Aβ IgG1 mAb)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pleural Drainage Systems on Reducing Pleural Effusion Formation Following Lung Resection
Status: COMPLETED
Conditions: Lung Neoplasms|Pleural Effusion
Interventions: DEVICE: Medela Thopaz Thoracic Drainage System|DEVICE: Atrium Express Dry Seal Chest Drain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cervical Cancer Screening Study in Brazil
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: PROCEDURE: Wide-Field White Light Imaging|DRUG: Acetic Acid|DRUG: Proflavine Solution|PROCEDURE: Wide-Field Fluorescence Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies
Status: COMPLETED
Conditions: Herpes Simplex|HIV Infections
Interventions: DRUG: Foscarnet sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Mantle Cell Lymphoma|Refractory Mantle Cell Lymphoma
Interventions: DRUG: Copanlisib Hydrochloride|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of App-assisted Home Exercise Program in Patients With Frozen Shoulder
Status: RECRUITING
Conditions: Frozen Shoulder
Interventions: DRUG: Glenohumeral joint and subacromial space triamcinolone injections|DEVICE: App-assisted exercise|DRUG: Nonsteroidal anti-inflammatory drugs (aceclofenac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rucaparib Maintenance Therapy in Advanced Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer
Interventions: DRUG: Rucaparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Apadenoson for Detection of Myocardial Perfusion Defects Using SPECT MPI
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Apadenoson SPECT-MPI|DRUG: Adenosine SPECT-MPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radioembolization With Yttrium-90 Microspheres for Intermediate or Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Liver Cancer
Interventions: DEVICE: Yttrium-90 microspheres (Therasphere MDS Nordion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of AdimFlu-S, Formulation 2010-2011, in Infants Aged Between 6-12months Old
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: AdimFlu-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Prophylactic Postoperative Antibiotics in HoLEP
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia|Urinary Tract Infections
Interventions: DRUG: Nitrofurantoin|DRUG: Cephalexin|DRUG: Sulfamethoxazole Trimethoprim Combination|DRUG: Ciprofloxacin|PROCEDURE: Holmium Laser Enucleation of prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Menthol for PDT Pain Relief
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Menthol|DRUG: Aqueous Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EFFECTS OF AROMATHERAPY MASSAGE ON LACTATION IN NON-BREASTFEEDING MOTHERS WITH PREMATURE NEWBORNS IN NEONATAL INTENSIVE CARE UNIT
Status: COMPLETED
Conditions: LACTATION IN MOTHERS WITH PREMATURE NEWBORNS
Interventions: OTHER: aromatherapy massage|OTHER: back massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Autologous Blood Injection Versus Platelet Rich Plasma on Chronic Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: BIOLOGICAL: PRP injection|BIOLOGICAL: ABI injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Edoxaban in Patients With Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure
Status: UNKNOWN
Conditions: Non-Valvular Atrial Fibrillation|Left Atrial Appendage Closure
Interventions: DRUG: Edoxaban|DEVICE: WATCHMAN LAA Closure|DRUG: Aspirin and Clopidogrel|DRUG: Aspirin and Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Stimulation to Treat Low Back Pain
Status: WITHDRAWN
Conditions: Low Back Pain|Lumbar Back Pain|Lumbago
Interventions: PROCEDURE: Spinal Cord Stimulator Lead Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction (ACLR)
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture|Quadriceps Muscle Atrophy
Interventions: OTHER: Cross-education and blood flow restriction training|OTHER: Cross-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Status and Quality of Life in the Elderly
Status: TERMINATED
Conditions: Quality of Life
Interventions: DIETARY_SUPPLEMENT: AMP-886|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab Administration
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: Natalizumab|DRUG: Natalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Heparin Formulations in Patients With Chronic Renal Failure.
Status: UNKNOWN
Conditions: Thrombus
Interventions: BIOLOGICAL: heparin sodium - APP|BIOLOGICAL: Heparin sodium - Hipolabor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Atovaquone / Proguanil 250/100 mg|DRUG: Tegoprazan 50 mg|DRUG: Esomeprazole 40 mg|DRUG: Vonoprazan 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Efficacy and Safety of Somatostatin Used as Inflow Modulator in Liver Transplantation.
Status: COMPLETED
Conditions: Liver Transplant With Clinically Significant Portal Hypertension
Interventions: DRUG: Administration of Somatostatin|DRUG: Administration of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraabdominal Chloroprocaine During Cesarean Delivery for Pain Control
Status: WITHDRAWN
Conditions: Cesarean Section Complications|Pain
Interventions: DRUG: Chloroprocaine Hcl 2% Inj|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Embedded Palliative Care in the MICU
Status: RECRUITING
Conditions: Critical Illness|End of Life|Quality of Life
Interventions: OTHER: Embedded Hospice and Palliative Care Practitioner|OTHER: Embedded Hospice and Palliative Care Practitioner (Group Effect)|OTHER: None (Historical)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MorbiMortality Amelioration in Preeclamptic Primiparas Study. MoMA Pre Prim Study
Status: COMPLETED
Conditions: Pregnancy|Primiparity|Hypertension|Preeclampsia|Intrauterine Growth Retardation
Interventions: OTHER: Transmission of sFlt-1 results to the investigator|OTHER: No transmission of the sFlt-1 results to the investigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pleural Cryobiopsies During Semirigid Thoracoscopy: A New Technique
Status: COMPLETED
Conditions: Pleural Effusion|Pleural Diseases
Interventions: DEVICE: Cryobiopsy (Autoclavable cryoprobe 20416-032)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Occipital Nerve Stimulation in the Treatment of Migraine
Status: TERMINATED
Conditions: Migraine
Interventions: DEVICE: Stimulation of the Occipital Nerves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hypnosis on Pain and Anxiety During Lumbar Puncture for Etiological Diagnosis of Cognitive Impairment
Status: UNKNOWN
Conditions: Cognitive Impairment|Alzheimer's Disease
Interventions: BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early-Start Antiplatelet Treatment After Neurosurgery in Patients With Spontaneous Intracerebral Hemorrhage
Status: UNKNOWN
Conditions: Spontaneous Intracerebral Hemorrhage
Interventions: DRUG: Antiplatelet Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Alpha Lipoic Acid for the Treatment and Prevention of Diabetic Retinopathy
Status: TERMINATED
Conditions: Moderate Non-proliferative Diabetic Retinopathy
Interventions: DIETARY_SUPPLEMENT: Alpha Lipoic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Galantamine CR|DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MRgFUS in the Treatment of Osteoarthritic Knee Pain
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Osteoarthritis|Osteoarthritis, Knee
Interventions: DEVICE: MRgFUS Treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lanreotide Microparticles as Palliative Treatment in Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Intestinal Obstruction|Carcinoma|Peritoneal Neoplasms
Interventions: DRUG: Lanreotide (microparticle formulation)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Focal Salvage HDR Brachytherapy for Locally Recurrent Prostate Cancer in Patients Treated With Prior Radiotherapy
Status: UNKNOWN
Conditions: Locally Recurrent Prostate Cancer
Interventions: RADIATION: HDR Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Meal Frequency on Glycemic Control of People at High Risk or Diagnosed With Diabetes
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Hyperinsulinism|Poor Glycemic Control|Hyperglycemia|Insulin Sensitivity
Interventions: OTHER: Isocaloric diet with 3 meals|OTHER: Isocaloric diet with 6 meals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement Training and Feedback System: Family-Based Services
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Core Training: FBS System Mapping and MTFS-I Installation|BEHAVIORAL: Core Training & Facilitation: FBS System Mapping and MTFS-I Installation plus monthly on-site meetings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gestational Diabetes: Induction Versus Expectant Management of Labour
Status: COMPLETED
Conditions: Gestational Diabetes|Gestational Diabetes Mellitus|Diabetes Mellitus, Gestational|Pregnancy-Induced Diabetes|Diabetes, Pregnancy Induced
Interventions: OTHER: INDUCTION of LABOUR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Role of Steroids and 10% Hypertonic Sodium Chloride in Adhesiolysis in Post Lumbar Surgery Syndrome Patients
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Risdiplam (RO7034067) in Adult and Pediatric Participants With Spinal Muscular Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Cognitive Effects of Fesoterodine in Elderly Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 4mg fesoterodine|DRUG: 8mg fesoterodine|DRUG: alprazolam 1mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Home Support for Mothers Whose Premature Infants
Status: COMPLETED
Conditions: Infant, Premature, Diseases|Mothers
Interventions: BEHAVIORAL: Providing guidance after discharge routine procedure and calling one week after discharge.|BEHAVIORAL: Discharge routine procedure.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ultra Protective Ventilation Without Extracorporeal Circulation in Severe ARDS Patients (VT4ARDS)
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome
Interventions: OTHER: Tidal volume reduction to 4 ml/kg Predicted Body Weight (PBW)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Abuse Potential of AZD7325 in Healthy Recreational Central Nervous System (CNS) Depressant Users
Status: COMPLETED
Conditions: Recreational CNS Depressant Use
Interventions: DRUG: Lorazepam|DRUG: AZD7325|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Bone Neoplasms
Interventions: DRUG: AZD0530|DRUG: Zoledronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: acalabrutinib|DRUG: placebo|DRUG: Prednisone|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human and Proof-of-Mechanism Study of ARC19499 Administered to Hemophilia Patients
Status: TERMINATED
Conditions: Hemophilia
Interventions: DRUG: placebo control|DRUG: ARC19499
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa
Status: RECRUITING
Conditions: Hypophosphatasia
Interventions: DRUG: ALXN1850|DRUG: asfotase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Postherpetic Neuralgia
Status: COMPLETED
Conditions: Neuralgia, Postherpetic
Interventions: DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combination Mindfulness Spiritual-Based Cognitive Therapy Plus Hypnosis in HIV Patients With Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Combination mindfulness spiritual-based cognitive therapy plus hypnosis|BEHAVIORAL: Mindfulness-based cognitive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoraflex™ Hybrid IDE Study
Status: COMPLETED
Conditions: Aortic Aneurysm|Aortic Dissection|Aortic Rupture
Interventions: DEVICE: Thoraflex™ Hybrid Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal High Flow to Maintain the Benefits of Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Patients
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nasal high flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3090106 in Japanese and Caucasian Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3090106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug Eluting Balloon Angioplasty for Dialysis Access Treatment
Status: COMPLETED
Conditions: Dialysis|Angioplasty
Interventions: DEVICE: Percutaneous Transluminal Angioplasty (PTA)|DEVICE: Percutaneous Transluminal Angioplasty (PTA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux
Status: TERMINATED
Conditions: Laryngopharyngeal Reflux
Interventions: DRUG: dexlansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Upfront Maintenance Olaparib in Advanced Ovarian Cancer BRCAwt Patients With Known Homologous Recombination Deficiency
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Olaparib tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety, Tolerability And Immunogenicity Of A 13-Valent Pneumococcal Conjugate Vaccine (13vPnC)
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: 13 valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 23vPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebral Cortical Influences on Autonomic Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Subjects|Functional Dyspepsia|Irritable Bowel Syndrome
Interventions: DEVICE: rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Using PK Morcellator With Pneumoliner Containment Hysterectomy
Status: WITHDRAWN
Conditions: Gynecologic Surgery
Interventions: DEVICE: Olympus PK Morcellator in PneumoLiner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
Status: WITHDRAWN
Conditions: Stenosis|Herniated Nucleus Pulposus|Degenerative Disc Disease|Spondylosis|Myelopathy|Radiculopathy|Myeloradiculopathy
Interventions: DRUG: Methylprednisolone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation Safety and Pharmacokinetic Study of AVE9633 as Single Agent in Relapsed/Refractory CD33-Positive Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Myeloid Leukemia
Interventions: DRUG: AVE9633
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Decrease Anxiety in Parents of Infants in the Neonatal Intensive Care Unit (NICU)
Status: COMPLETED
Conditions: Anxiety|Acute Stress Disorder|Posttraumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Brief Cognitive Behavioral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Apremilast as a Direct Treatment for Mild-to-moderate Plaque Psoriasis Versus Placebo: an Analysis of Clinical Safety and Efficacy
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Apremilast|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pursed-Lip Breathing on Blood Pressure and Heart Rate
Status: COMPLETED
Conditions: Hypertensive Urgency
Interventions: OTHER: Non-pharmacologic treatment; Pursed-Lip Breathing Combined with Number Counting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Androgen Suppression With Stereotactic Body or External Beam Radiation Therapy (ASSERT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: stereotactic ablative radiotherapy|RADIATION: external beam radiation therapy|DRUG: Zoladex ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of LPEC Compared With a Sham Procedure in the General Anesthesia
Status: UNKNOWN
Conditions: Intubation;Difficult
Interventions: OTHER: Check the condition of intubation with LPEC compared with a sham procedure in the general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Measles, Mumps and Rubella (MMR) Vaccine (209762) Compared to Merck & Co., Inc.'s MMR Vaccine in Healthy Children 12 to 15 Months of Age
Status: COMPLETED
Conditions: Measles; Mumps; Rubella|Measles-Mumps-Rubella Vaccine
Interventions: BIOLOGICAL: Priorix|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax|BIOLOGICAL: Havrix|BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Prevention of Re-emergence of Depression Symptoms
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2216684|DRUG: Placebo|DRUG: SSRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potassium Supplementation in CKD
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic|Potassium Depletion|Hypertension|Hyperkalemia
Interventions: DIETARY_SUPPLEMENT: Potassium Chloride|DIETARY_SUPPLEMENT: Potassium Citrate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine-ketamine Versus Propofol-ketamine for Sedation During Endoscopy in Hepatic Patients
Status: COMPLETED
Conditions: Anesthesia; Reaction
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regional Midazolam in Quadratus Lumborum Block
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Midazolam/ bupivaciane|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Self-administrable Psychological Intervention Programs Supported by New Technologies as a Treatment for Patients With Functional Digestive Disorders.
Status: RECRUITING
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: Psychological intervention|BEHAVIORAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Fluzone High Dose in Immunocompromised Children and Young Adults
Status: COMPLETED
Conditions: Solid Organ Transplant Recipient (Liver, Kidney, Heart)|Rheumatologic Disorder|Human Immunodeficiency Virus (HIV)|Bone Marrow Transplant (BMT)|Dialysis
Interventions: BIOLOGICAL: Fluzone High Dose|BIOLOGICAL: Fluzone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of a Semi-Quantitative Urine Pregnancy Test and Pregnancy Questionnaire After Uterine Evacuation for Undesired Pregnancy of Uncertain Location
Status: COMPLETED
Conditions: Follow-up After Uterine Evacuation
Interventions: DEVICE: dBest semi-quantitative urine pregnancy test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Does Omeprazole Decrease Intestinal Calcium Absorption?
Status: COMPLETED
Conditions: Osteoporosis|Achlorhydria|GERD|Hip Fracture
Interventions: DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: An Extension Study to Examine the Safety and Tolerability of a New Drug in Patients With Symptoms of Overactive Bladder (OAB).
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Vibegron|DRUG: placebos|DRUG: Tolterodine Tartrate ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Effectiveness and Safety of Abciximab in Patients With Acute Ischemic Stroke (AbESTT-II)
Status: TERMINATED
Conditions: Cerebrovascular Accident|Brain Ischemia|Acute Disease
Interventions: DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Rituximab-HyperCVAD (R-HCVAD) Alternating With Rituximab-Methotrexate-Cytarabine- (R-MC) in Newly Diagnosed Patients With Diffuse Large B-Cell Lymphoma With MYC-Rearrangement.
Status: WITHDRAWN
Conditions: Newly Diagnosed Diffuse Large B-Cell Lymphoma|Intermediate (Burkitt-Like) Lymphoma
Interventions: DRUG: R-HCVAD and R-MC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Alpha-emitter Therapy of PRRT Naïve and Previous PRRT Neuroendocrine Tumor Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: AlphaMedix
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing an Education- and Health System Task-shifting Approach for Child Mental Health Promotion in Uganda
Status: RECRUITING
Conditions: Mental Health Issue|Stigma, Social|Child Development|Child Abuse
Interventions: OTHER: Adapted version of the mhGAP-IG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Micro-nutritional Status and Gut Microbiota in Morbidly Obese Patients Before and After Gastric Bypass
Status: COMPLETED
Conditions: Obesity|Bariatric Surgery Candidate
Interventions: DRUG: Diet supplementation|PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of Multiple Doses of Isavuconazole and a Single Dose of Bupropion
Status: COMPLETED
Conditions: Pharmacokinetics of Isavuconazole|Pharmacokinetics of Bupropion|Healthy Volunteers
Interventions: DRUG: Isavuconazole|DRUG: bupropion hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Dose-finding Study to Investigate the Safety and Immunogenicity of Two Vaccinations With FSME IMMUN NEW in Healthy Volunteers Aged 1 to 6 Years.
Status: COMPLETED
Conditions: Tick-borne Encephalitis
Interventions: BIOLOGICAL: Tick-borne Encephalitis Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate Comparative Efficacy, Safety and Immunogenicity Between AVT16 and Entyvio
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: AVT16|BIOLOGICAL: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota Transfer for Chronic Rhinosinusitis
Status: RECRUITING
Conditions: Sinusitis, Chronic|Sinus Disease|Sinus Infection|Sinus Infection Chronic
Interventions: PROCEDURE: Sinonasal Microbiota Transfer|PROCEDURE: Sham Sinonasal Microbiota Transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leukocytes - ObeSity - Spontaneous Labour
Status: COMPLETED
Conditions: Pre-conceptional Obesity
Interventions: OTHER: Blood samples at 37-38 Weeks of amenorrhea|OTHER: Blood samples at 41 Weeks of amenorrhea if prolonged pregnancy|OTHER: Blood samples at the time of delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: OTHER
Clinical trial: Melphalan and Bortezomib Prior to Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: TERMINATED
Conditions: Plasma Cell Myeloma|Plasmacytosis|Recurrent Plasma Cell Myeloma|Smoldering Plasma Cell Myeloma
Interventions: DRUG: Melphalan|DRUG: Bortezomib|DRUG: Dexamethasone|PROCEDURE: Autologous Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing A Fixed Dose Combination Formulation, Rin 150 And Individual Reference Drugs In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: RIN 150|DRUG: reference drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Trial of Anti-CD74 (hLL1) Antibody Therapy in B Cell Malignancies
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: hLL1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder
Status: RECRUITING
Conditions: Tobacco Use Disorder
Interventions: DRUG: Psilocybin|DRUG: Niacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: IDEC-C2B8 (rituximab)|DRUG: Placebo|DRUG: Methotrexate|DRUG: Etanercept|DRUG: Adalimumab|DRUG: Methylprednisolone|DIETARY_SUPPLEMENT: Folate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Multiple Myeloma|Myelodysplastic Syndromes
Interventions: DRUG: cyclophosphamide|DRUG: fludarabine phosphate|RADIATION: Total body irradiation|BIOLOGICAL: Umbilical cord blood unit with C3a fragment|BIOLOGICAL: Unmanipulated UCB Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Fat Plant-based Diet Effects on Body Composition Indices
Status: COMPLETED
Conditions: Obesity|Weight Loss
Interventions: BEHAVIORAL: Low fat plant-based diet|BEHAVIORAL: Lectures on health effects of a low fat plant-based diet.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of Combined Treatment for Veterans With Chronic Pain & Opiate Misuse
Status: COMPLETED
Conditions: Chronic Pain|Problematic Opioid Use
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy + Mindfulness-Based Relapse Prevention + Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutraceutical Composition Containing Natural Products Derivatives on the Modulation of the Endocrine Neuroimmune Axis
Status: COMPLETED
Conditions: Insulin Resistance|Inflammatory Bowel Diseases|Overweight and Obesity|Healthy
Interventions: DIETARY_SUPPLEMENT: Composition with Silymarin|DIETARY_SUPPLEMENT: Low-mineral composition without Silymarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER