pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children
Status: COMPLETED
Conditions: Oncological Children
Interventions: DRUG: nebulized ketamine|DRUG: nebulized Dexmedetomidine|DRUG: nebulized midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of DW-0919 & DW-0920 in Healthy Male Volunteers Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DW-0920|DRUG: DW-0919
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Naloxegol and Opioid-induced Constipation
Status: UNKNOWN
Conditions: Constipation|Constipation Drug Induced
Interventions: DRUG: Naloxegol 25 MG|OTHER: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Remetinostat Gel as Neoadjuvant Therapy in Patients With Squamous Cell Carcinoma (SCC)
Status: TERMINATED
Conditions: Squamous Cell Carcinoma
Interventions: DRUG: Remetinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Novel Ibuprofen Acetaminophen Combination Formulations in the Treatment of Post-surgical Dental Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ibuprofen/acetaminophen|DRUG: Ibuprofen/acetaminophen|DRUG: Ibuprofen/acetaminophen|DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
Status: RECRUITING
Conditions: Cutaneous Melanoma|Merkel Cell Carcinoma|Skin Squamous Cell Carcinoma
Interventions: DRUG: Eutectic Mixture of Local Anesthetics|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Orthopaedic Outcomes Network (MOON) ACL Reconstruction (ACLR): 10 Year Onsite Follow-up
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis|Arthritis|Joint Diseases|Musculoskeletal Diseases|Rheumatic Diseases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Polyglutamate Paclitaxel and Carboplatin in Treating Patients With Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Carcinoma|Malignant Ovarian Mixed Epithelial Tumor|Ovarian Brenner Tumor|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Primary Peritoneal Carcinoma|Stage III Ovarian Cancer|Stage IV Ovarian Cancer|Undifferentiated Ovarian Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel Poliglumex|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab (RoActemra) and Tranexamic Acid (Cyklokapron) Used as Adjuncts to Chronic Subdural Hematoma Surgery
Status: TERMINATED
Conditions: Chronic Subdural Hematoma
Interventions: COMBINATION_PRODUCT: Tranexamic acid and Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing With Dyslipidemic Adolescents Together With a Parent Versus With Adolescents Alone: A Mixed Methods Clinical Trial
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: OTHER: Motivational Interviewing/Counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Drug-Drug Interaction of SHR4640 and Febuxostat in Patients With Hyperuricemia
Status: UNKNOWN
Conditions: Hyperuricemia
Interventions: DRUG: SHR4640 dose1|DRUG: Febuxostat dose2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation
Status: RECRUITING
Conditions: Candidemia|Mycoses|Fungal Infection|Fungemia|Invasive Candidiasis|Pneumocystis|Mold Infection|Invasive Fungal Disease|Prophylaxis of Invasive Fungal Infections|Aspergillus
Interventions: DRUG: Rezafungin for Injection|DRUG: Posaconazole|DRUG: Fluconazole|DRUG: Trimethoprim-sulfamethoxazole (TMP/SMX)|DRUG: Intravenous Placebo|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anfibatide Phase Ib-IIa Clinical Trial
Status: COMPLETED
Conditions: Non-ST Segment Elevation Myocardial Infarction
Interventions: DRUG: Anfibatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Midazolam on the Quality of Postoperative Recovery
Status: COMPLETED
Conditions: Postoperative Period|Anxiety|Fatigue|Depression|Aggression
Interventions: DRUG: Midazolam|DRUG: NaCl (sodium chloride) 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetics of HIV-RNA Decay in Seminal Plasma of Men Treated by Dolutegravir at the Time of Primary HIV Infection
Status: COMPLETED
Conditions: HIV Infection Primary
Interventions: DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NGAL and Its Association With the No-reflow Phenomenon in ST-elevation Myocardial Infarction
Status: UNKNOWN
Conditions: No-Reflow Phenomenon|STEMI - ST Elevation Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: NGAL levels early and post STEMI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect of Low Level Laser Light Therapy on Reducing the Appearance of Cellulite in the Thighs and Buttocks.
Status: COMPLETED
Conditions: Cellulite
Interventions: DEVICE: Erchonia Scanner device (GLS)|DEVICE: Placebo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near Patient Study of the OraQuick ADVANCE® HIV-1/2 Rapid Antibody Test in Oral Fluid and Fingerstick Whole Blood
Status: COMPLETED
Conditions: HIV Testing|HIV Infections
Interventions: DEVICE: OraQuick ADVANCE® HIV-1/2 Rapid Antibody Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Vitrectomy Under Local Anesthesia
Status: UNKNOWN
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: PLACEBO|DRUG: Dexamethasone|DRUG: Ondansetron|DRUG: Dexamethasone + Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of CFR and Iron Supplementation on Iron Status and Gut Microbiota of 1-2 Years Old Myanmar Children
Status: UNKNOWN
Conditions: Iron Deficiency|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Iron supplementation|OTHER: CFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tailoring of Vaccine-Focused Messages: Moral Foundations
Status: COMPLETED
Conditions: Childhood Vaccinations
Interventions: BEHAVIORAL: Baseline Survey|BEHAVIORAL: Pre-intervention Survey|BEHAVIORAL: Morally Congruent Message|BEHAVIORAL: Morally Non-Congruent Message|BEHAVIORAL: Control Message|BEHAVIORAL: Post-Intervention Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Triple-Negative Breast Carcinoma
Interventions: RADIATION: Radiation Therapy|BIOLOGICAL: Pembrolizumab|DRUG: Nab-paclitaxel|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine|PROCEDURE: Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Bone Scan|PROCEDURE: Biospecimen Collection|OTHER: Medical Chart Review
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting With or Without Synchronization
Status: RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: DEVICE: ABFnoS then ABFS (Cochlear implant)|DEVICE: ABFS then ABFnoS (Cochlear implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: ASpirin for Patients With SEPsis and SeptIc Shock
Status: TERMINATED
Conditions: Sepsis
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT to Evaluate STERN FIX Device as a Sternal Stabilization System in Patients After Sternotomy
Status: RECRUITING
Conditions: Median Sternotomy
Interventions: DEVICE: Combination of STERN FIX and wires|DEVICE: Wires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dianeal, Extraneal, Nutrineal (D-E-N) Versus Dianeal Only in Diabetic Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients
Status: COMPLETED
Conditions: End Stage Renal Disease (ESRD)|Diabetes|CAPD
Interventions: DRUG: Dianeal|DRUG: Dianeal, Extraneal, Nutrineal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Superiority Study of Vernakalant vs Amiodarone in Subjects With Recent Onset Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Vernakalant Injection|DRUG: Amiodarone Injection:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rehabilitation in SOD1 ALS Treated With Tofersen
Status: ENROLLING_BY_INVITATION
Conditions: Amyotrophic Lateral Sclerosis|Lou Gehrig Disease|Familial Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Motor Neuron Disease, Familial
Interventions: BEHAVIORAL: Rehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Switch of Renin-Angiotensin System Inhibitors in Patients With Covid-19
Status: TERMINATED
Conditions: Covid19|Angiotensin II Receptor Antagonist Adverse Reaction
Interventions: DRUG: Renin-angiotensin system inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gelatin Tannate in Treatment Acute Gastroenteritis in Children.
Status: COMPLETED
Conditions: Acute Gastroenteritis
Interventions: DRUG: Gelatin Tannate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AC6 Gene Transfer for CHF
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DRUG: Ad5.hAC6|DRUG: Sucrose (3%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Doses Vitamin C and Tissular Repair in Surgical Patients
Status: COMPLETED
Conditions: Tissue Damage
Interventions: DIETARY_SUPPLEMENT: Vitamin C|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Surgery and Thermal Hepatic Ablation Combined With Chemotherapy in Hepatic Oligometastatic Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Thermal Ablation|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-dopa Versus Dopamine Agonists After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DRUG: L-dopa|DRUG: Dopamine Agonists (pramipexole, ropirinole)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Safety And Efficacy Of Moroctocog Alfa (AF-CC) In Previously Treated Hemophilia A Patients
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Moroctocog alfa ( AF-CC)|PROCEDURE: Laboratory tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: favezelimab/pembrolizumab|DRUG: regorafenib|DRUG: TAS-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Human Laryngeal Evoked Brainstem Potentials
Status: COMPLETED
Conditions: Thyroidectomy
Interventions: PROCEDURE: Placement of a needle electrode through the thyrohyoid membrane into the submucosal space within the false vocal fold
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial to Determine the Efficacy/Safety of Plitidepsin vs Control in Patients With Moderate COVID-19 Infection
Status: TERMINATED
Conditions: COVID-19 Infection
Interventions: DRUG: Plitidepsin|DRUG: Dexamethasone|DRUG: Remdesivir|DRUG: Favipiravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerised Training for Binge-Subtype Eating Disorders
Status: UNKNOWN
Conditions: Bulimia Nervosa|Binge-Eating Disorder
Interventions: BEHAVIORAL: Food-Specific Inhibitory Control Training (FoodT App)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture vs Sham Acupuncture or Waitlist Control for Patients With Chronic Planter Fasciitis
Status: UNKNOWN
Conditions: Plantar Fasciitis
Interventions: OTHER: Acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Textured Food Introduction Information and Parental Feeding Practices
Status: COMPLETED
Conditions: Feeding Practices|Food Acceptance
Interventions: BEHAVIORAL: Counselling on textured food introduction between 8 and 15 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NWRD06 DNA Plasmid for HCC After Radical Resection
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: 1mg NWRD06 administered by electroporation|BIOLOGICAL: 4mg NWRD06 administered by electroporation|BIOLOGICAL: 8mg NWRD06 administered by electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TYR Sphere
Status: COMPLETED
Conditions: Tyrosinemias|Alkaptonuria|Tyrosinemia, Type I|Tyrosinemia, Type II|Tyrosinemia, Type III
Interventions: DIETARY_SUPPLEMENT: TYR sphere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia Trait
Status: NOT_YET_RECRUITING
Conditions: Thalassemia|Folic Acid Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Folic acid|DIETARY_SUPPLEMENT: Materna
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: S-1+Oxaliplatin vs.S-1+Cisplatin First-line Treatment of Advanced or Recurrent Non-intestinal Type Gastric Adenocarcinoma Patients
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: S-1|DRUG: Oxaliplatin|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Delirium|Cognitive Impairment|Alzheimer; Early Onset|Trauma|Polytrauma|Traumatic Brain Injury|ICU|Critical Illness
Interventions: OTHER: Non-interventional observational prospective cohort study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NightWare and Cardiovascular Health in Veterans With PTSD
Status: NOT_YET_RECRUITING
Conditions: Post-traumatic Stress Disorder (PTSD)|Cardiovascular Diseases|Autonomic Dysfunction|Vascular Stiffness|Nightmare|Endothelial Dysfunction|Veteran
Interventions: DEVICE: NightWare
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Caudal VS Dorsal Penile Nerve Block for Postoperative Analgesia After Circumcision
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Caudal nerve block /neuroaxial|PROCEDURE: Dorsal penile nerve block|PROCEDURE: Combined caudal and dorsal penile nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Invictus Medical, Medical Cranial Support Device (CSD) is a Device Safety Study in Infants at Risk of Head Ulcers.
Status: WITHDRAWN
Conditions: Other Preterm Infants
Interventions: DEVICE: HCP will place the Invictus Cranial Support Device (CSD) on the patient|OTHER: human intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Bioequivalence Study (Preliminary Study) of Ritonavir Versus NORVIR in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Ritonavir Tablet 100mg|DRUG: NORVIR tablet 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety, Efficacy, PK, and Extrapulmonary Pharmacodynamics (PD) of Albuterol Sulfate Pressurized Inhalation Suspension (Hereafter Referred to as AS MDI) Compared to Proventil as an Active Control in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AS MDI|DRUG: Proventil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Application of Clove Gel Versus Benzocaine Gel on Pain Reduction During Application of Simple Dental Procedures in Children.
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: OTHER: clove gel|OTHER: Benzocaine gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.
Status: TERMINATED
Conditions: Basal Cell Carcinoma|Nevoid Basal Cell Carcinoma Syndrome|Gorlin Syndrome
Interventions: DRUG: verteporfin PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women
Status: COMPLETED
Conditions: Smoking|Nicotine Dependence
Interventions: DRUG: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiographic Changes in the Maxillary Sinus Following Closed Sinus Augmentation
Status: RECRUITING
Conditions: Dental Implant
Interventions: OTHER: 3D R100 scanner|OTHER: Conventional Radiograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Lactation-Focused Motivational Interviewing
Status: COMPLETED
Conditions: Breast Feeding|Lactation Puerperal Increased|Infant Behavior|Maternal Behavior
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Psychoeducation Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Tests: Nasopharyngeal Swab vs Saliva Collected With Salivette® Cortisol for Viral RNA Sampling for RT-qPCR
Status: COMPLETED
Conditions: Covid-19
Interventions: DIAGNOSTIC_TEST: Sampling of SARS-CoV-2 RNA from nasopharyngeal swab specimen or saliva collected via Salivette Cortisol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: SOLFAMU Study of Nasal Brushing Collected OLFActory MUcosa Samples in the Diagnosis of Human Encephalopathies
Status: UNKNOWN
Conditions: Encephalopathy|HIV-encephalopathy|Alzheimer Dementia
Interventions: DEVICE: Nasal Brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Efficacy Study of Inhaled Albuterol Delivered With Akita Breath Control
Status: UNKNOWN
Conditions: Asthma
Interventions: PROCEDURE: aerosol drug deposition strategies|DRUG: Albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: OBT076, a CD205-directed antibody-drug conjugate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Topical Besifloxacin on Ocular Surface Bacterial Microbiota Prior to Cataract Surgery
Status: COMPLETED
Conditions: Microbial Disease|Cataract Senile
Interventions: DRUG: Besifloxacin Ophthalmic|DRUG: Hydroxypropyl Methylcellulose Ophthalmic Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implant for Augmentation of Cerebral Blood Flow Trial, Effectiveness and Safety in a 24 Hour Window
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Active Sphenopalatine Ganglion (SPG) Stimulation|DEVICE: Sham Sphenopalatine Ganglion (SPG) Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACHP-THP vs EC-THP as Neoadjuvant Therapy for HER2-positive EBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Neoadjuvant Chemotherapy
Interventions: DRUG: Doxorubicin liposome|DRUG: Cyclophosphamide|DRUG: Trastuzumab|DRUG: Docetaxel|DRUG: Epirubicin|DRUG: Pertuzumab|DRUG: Paclitaxel|DRUG: Paclitaxel-albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Treatment and RIPC in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Acute Ischemic Stroke|Endovascular Treatment
Interventions: DEVICE: RIPC device (IPC-906X)|DRUG: foundational treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Comfort of Lubricant Eye Drop FID 111421
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Lubricant Eye Drop FID 111421|OTHER: Optive Lubricant Eye Drop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis for Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment
Status: UNKNOWN
Conditions: Dissecting Aneurysm of Cerebral Artery
Interventions: DEVICE: intracranial stent, flow diverter and coils
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Dietary Fiber Supplementation on Colonic Mucosal Microbiome
Status: RECRUITING
Conditions: Benign Colorectal Neoplasm|Non-Neoplastic Anal Disorder
Interventions: DIETARY_SUPPLEMENT: Dietary Fiber|PROCEDURE: Proctoscopy or anoscopy with Biopsy|PROCEDURE: Colonoscopy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Everolimus in Treating Patients With Recurrent Low-Grade Glioma
Status: COMPLETED
Conditions: Adult Diffuse Astrocytoma|Adult Mixed Glioma|Adult Oligodendroglioma|Adult Subependymal Giant Cell Astrocytoma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Everolimus|OTHER: Archival Tissue Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyanoacrylate With or Without Suture?
Status: COMPLETED
Conditions: Wound Heal
Interventions: DEVICE: Gelatin sponge stabilization with suture and cyanoacrylate|PROCEDURE: Gelatin sponge stabilization with cyanoacrylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a New Shortness of Breath With Daily Activities Questionnaire in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Fluticasone propionate/salmeterol combination product|DRUG: Salmeterol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Nyaditum Resae® as a Co-adjuvant During Treatment for Active Pulmonary Tuberculosis and Its Impact on the Gut Microbiota
Status: RECRUITING
Conditions: Tuberculosis
Interventions: DIETARY_SUPPLEMENT: Nyaditum resae®|OTHER: Mannitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: S-Ibuprofen|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioenergetics and Protein Metabolism in Sporadic Amyotrophic Lateral Sclerosis
Status: UNKNOWN
Conditions: Sporadic Amyotrophic Lateral Sclerosis
Interventions: OTHER: Skin Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intranasal Fentanyl Versus Oral Morphine Sulfate in the Treatment of Pain in Pediatric Trauma
Status: TERMINATED
Conditions: Pain, Acute
Interventions: DRUG: Intranasal fentanyl + Oral Placebo|DRUG: Oral Morphine + Intranasal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mesh Fixation and Non-Fixation in eTEP
Status: RECRUITING
Conditions: Migration of Implant|Pain|Postoperative Complications|Relapse
Interventions: PROCEDURE: Mesh Fixation|PROCEDURE: No Mesh Fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Shoes Insoles on Symptoms and Disease Progression in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Laterally wedged shoe insoles|DEVICE: Control insole group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: cArdiopulmonary exerCise Test Assessing Multiple biOmarkers and Hormones iN Type 1 diabetEs Under Different Circumstances
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: CPET: CardioPulmonary Exercise Test for CSII users|OTHER: AEX1: Aerobic Exercise Test 1 for CSII users|OTHER: AEX2: Aerobic Exercise Test 2 for CSII users|OTHER: CPET: CardioPulmonary Exercise Test for MDI users|OTHER: AEX1: Aerobic Exercise Test 1 for MDI users|OTHER: AEX2: Aerobic Exercise Test 2 for MDI users
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Early Detection of Anastomotic Leakage by Microdialysis Catheters
Status: COMPLETED
Conditions: Pancreatic Cancer|Pancreaticoduodenal; Fistula|Pancreas; Fistula|Pancreatic Fistula
Interventions: PROCEDURE: Pancreaticoduodenectomy microdialysis catheter analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Characterization of the Role of Histamine in Children With Asthma
Status: COMPLETED
Conditions: Asthma|Allergic Asthma|Non-allergic Asthma
Interventions: DRUG: Levocetirizine 0.5 Mg/mL Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Gel Renewal During In-office Dental Bleaching
Status: UNKNOWN
Conditions: Tooth Bleaching
Interventions: OTHER: Dental Bleaching with 35% hydrogen peroxide gel + Violet LED Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis
Status: ENROLLING_BY_INVITATION
Conditions: Glenohumeral Osteoarthritis
Interventions: DEVICE: Anatomic total shoulder replacement|DEVICE: Reverse total shoulder replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma
Status: UNKNOWN
Conditions: Anaplastic (Malignant) Meningioma|Atypical Meningioma|Grade II Meningioma|Grade III Meningioma|Recurrent Meningioma|Supratentorial Meningioma
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Electric Field Therapy|DEVICE: NovoTTF-200A Device|PROCEDURE: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus
Status: TERMINATED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: Selinexor|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Hypertension|Hyperlipidemia
Interventions: OTHER: High risk assessment|OTHER: Low to moderate risk
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Beijing (Peking)---Myopia and Obesity Comorbidity Intervention (BMOCI)
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Myopia
Interventions: OTHER: A cluster randomized trial of a comprehensive intervention nesting family and clinic into school centered implementation to reduce myopia and obesity among children and adolescents in Beijing, China
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Imiquimod Treatment of Residual or Recurrent CIN Lesions: a Study Protocol
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Imiquimod|PROCEDURE: LLETZ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Team IntervenTion in CArdio-ONcology (TITAN Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Multidisciplinary team intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oral Dexamethasone as an Intervention for Postoperative Pain and Nausea Management in Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Arthritis Knee|Postoperative Nausea|Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-surgical Protocol for Frail Elderly People in Order to Reduce Hospitalization Days (APOPM).
Status: COMPLETED
Conditions: Surgery|Old Age; Debility|Frail Elderly Syndrome|Post-Operative Confusion|Older Adults|Perioperative Care|Urologic Diseases|Digestive Disease|Anesthesia|Nurse-Patient Relations
Interventions: OTHER: Timely pre-surgical conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Pain Associated With Fibromyalgia
Status: COMPLETED
Conditions: Pain Associated With Fibromyalgia
Interventions: DRUG: DS-5565|DRUG: Pregabalin|DRUG: Placebo tablet|DRUG: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Percutaneous Electrolysis in the Treatment of Achilles Tendinopathy
Status: RECRUITING
Conditions: Achilles Tendinopathy
Interventions: DEVICE: low intensity percutaneous musculoskeletal electrolysis|DEVICE: Sham application|OTHER: Silbernagel protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapidly Absorbable Versus Non-absorbable Sutures for Mohs Surgery Repair on the Face: a Randomized Controlled Split-scar Study
Status: COMPLETED
Conditions: Scars
Interventions: OTHER: rapidly absorbable suture (Vicryl Rapide)|OTHER: non-absorbable suture (Ethilon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time-Restricted Feeding
Status: COMPLETED
Conditions: Obesity|Inflammatory Markers|Glycemic Variation|Time Restricted Feeding|Ketosis
Interventions: OTHER: Time restricted feeding arm|OTHER: usual feeding pattern arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Treatment of Plantar Fasciitis: Physical Training, Glucocorticoid Injections or a Combination Thereof.
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: Training|DRUG: Glucocorticosteroid injection|BEHAVIORAL: Reduction in impact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Status: RECRUITING
Conditions: Labor Complication
Interventions: OTHER: Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prediction of Antidepressant Response Using Pharmacogenetics and Peripheral Lymphocytic Phenotype
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: responders|DRUG: non-responders
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Therapy With Autologous Cytokine-induced Killer Cells for Nonsquamous Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Autologous cytokine-induced killer cell|OTHER: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy
Status: UNKNOWN
Conditions: Parkinson Disease|Dyskinesia, Drug-Induced|Dyskinesias
Interventions: DRUG: Dipraglurant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain.
Status: TERMINATED
Conditions: Opioid-induced Constipation
Interventions: DRUG: Tegaserod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genomic Outcomes of Metformin
Status: COMPLETED
Conditions: Coronary Artery Disease|Mild Cognitive Impairment|Obesity, Abdominal|Hypertension
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Sleep-relieving Effect of Banana Peel Extract
Status: ACTIVE_NOT_RECRUITING
Conditions: Impaired Attention
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Banana peel extract
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Exercise and Nutritional Intervention in GI Cancer Patients
Status: RECRUITING
Conditions: Pancreatic Cancer|Gastric Cancer|Diet|Exercise
Interventions: BEHAVIORAL: Combined Exercise and Dietary Intervention (CEDI)|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Tarceva and Targretin Oral Capsules in Patients With Advanced Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: erlotinib and bexarotene
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-Centered Collaborative Care for Preventing Post-Traumatic Stress Disorder After Traumatic Injury
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|BEHAVIORAL: Motivational Interviewing|DRUG: FDA-Approved Anti-Anxiety Medications|BEHAVIORAL: Standard Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Oxytocin on Startle Hyperreactivity in Patients With AUD and PTSD
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Alcoholism
Interventions: DRUG: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin E-coated Polysulfone Membrane on Oxidative Stress, Inflammation and Monocytes in Critically Ill Patients in CRRT
Status: UNKNOWN
Conditions: Renal Failure|Renal Insufficiency, Acute
Interventions: DEVICE: ViE15-A|DEVICE: REXEED-15A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: SKB264|DRUG: Eribulin|DRUG: Capecitabine|DRUG: Gemcitabine|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipiodol Deposition Using Endhole vs. Pressure-Modulated Delivery
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Neuroendocrine Tumors
Interventions: DEVICE: TACE Catheters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep Brain Stimulation (DBS) at 60 Hz|DEVICE: Deep Brain Stimulation (DBS) at 130 Hz|DEVICE: Deep Brain Stimulation (DBS) Off (Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FluoroAv45 Imaging Research-in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment
Interventions: OTHER: neuropsychologic assessment|RADIATION: [18F]AV-45 PET|RADIATION: 18-FDG PET|OTHER: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Tosedostat in Combination With Cytarabine or Decitabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Myeloid Leukemia With Multilineage Dysplasia|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Secondary Acute Myeloid Leukemia|Secondary Myelodysplastic Syndromes|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: tosedostat|DRUG: cytarabine|DRUG: decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of ITX 5061 in Treatment-Naive Hepatitis C (HCV)-Infected Adults
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: ITX 5061|DRUG: Placebo ITX 5061
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Usage of Meropenem/Gentamicin Versus Ceftazidime/Avibactam in ARDS
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: meropenem|DRUG: ceftazidime 2 grams and avibactam 500|DEVICE: ventilator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of N-acetylcysteine as a Novel Adjuvant Treatment in Acute Organophosphorus Pesticide Poisoning
Status: COMPLETED
Conditions: Acute Organophosphorus Poisoned Patients
Interventions: DRUG: n acetyl cysteine|DRUG: standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Nutritional Intervention in Patients With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders|Stable Clinical Condition in the Last 3 Months
Interventions: DIETARY_SUPPLEMENT: Pyridoxine hydrochloride|OTHER: Tang orange powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT