pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Follow Up of Patients Chronic Hepatitis B (CHB) Treated With Sebivo Using the 13C Methacetin Breath Test
Status: WITHDRAWN
Conditions: Chronic Hepatitis B
Interventions: DEVICE: 13C Methacetin Breath Test (BreathID)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: High Frequency rTMS Treatment for Cognitive Impairments in Chronic Schizophrenia Patients
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: 10 Hz treatment group|DEVICE: 20 Hz treatment group|DEVICE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Whitening Dentifrice on Tooth Discoloration
Status: COMPLETED
Conditions: Tooth Discoloration
Interventions: OTHER: Conventional toothpaste|OTHER: Whitening toothpaste|OTHER: 10% carbamide peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Quantify Bacille Calmette Guerin (BCG) and Characterise the Immune Response After BCG Vaccination
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BCG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aquatic Treadmill Therapy for Improving Gait, Balance, Fitness and Quality of Life in Stroke Patients
Status: COMPLETED
Conditions: Ischemic or Hemorrhagic Stroke|Hemiparesis
Interventions: DEVICE: Aquatic treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Efficacy and Safety of Secukinumab in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondyloarthritis
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Erector Spinae Plane Block And Retrolaminar Block In Patients Undergoing VATS.
Status: RECRUITING
Conditions: Post-operative Analgesia|Retrolaminar Block|Erector Spinae Plan Block|VATS
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Retrolaminar block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Osteopathic Manipulative Treatment (OMT) on Proprioception in Adults
Status: COMPLETED
Conditions: Osteopathy in Diseases Classified Elsewhere
Interventions: PROCEDURE: Osteopathic Manipulative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Status: RECRUITING
Conditions: Anterior Cruciate Ligament Tear|Anterior Cruciate Ligament Rupture
Interventions: DRUG: Experimental Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Opioid Mortality in Illinois
Status: RECRUITING
Conditions: Opioid Use|Opioid-use Disorder
Interventions: BEHAVIORAL: Case Management and Peer Recovery|BEHAVIORAL: Naloxone-Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Digital Intervention to Treat Anxiety and Depression Among Persons Receiving Treatment for Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder|Anxiety Disorders|Depressive Disorder
Interventions: BEHAVIORAL: Smartphone-Based Digital Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CT011 Autologous CAR-T Cells in Patients With Hepatocellular Carcinoma at Risk of Recurrence After Surgical Resection
Status: RECRUITING
Conditions: HCC
Interventions: BIOLOGICAL: CT011 CAR-GPC3 T Cells Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT for Yinqiaosan-Maxingganshitang in the Treatment of COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Chinese Herb|DIAGNOSTIC_TEST: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pruritus
Interventions: DRUG: Linerixibat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparative Effectiveness Between ARNI and ACE Inhibitor/ARB Medication in Patient With HFrEF
Status: RECRUITING
Conditions: Heart Failure|Mortality
Interventions: DRUG: Angiotensin receptor neprilysin inhibitor (ARNI)|DRUG: Renin-Angiotensin System Inhibitor (RAS inhibitor)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial of LBL-024 Combined With Etoposide and Platinum in Patients With Advanced Neuroendocrine Carcinoma
Status: RECRUITING
Conditions: Advanced Neuroendocrine Carcinoma
Interventions: DRUG: LBL-024 for Injection|DRUG: Etoposide Injection|DRUG: Cisplatin for Injection|DRUG: Carboplatin Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Ibuprofen 600 mg Extended Release (ER) For Dental Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: ibuprofen|DRUG: ibuprofen|DRUG: naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery
Status: COMPLETED
Conditions: Ventricular Dysfunction, Left|Major Adverse Cardiac Events
Interventions: PROCEDURE: EGHEM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Reduce Hospitalizations in Children With Medical Complexity
Status: COMPLETED
Conditions: Chronic Illness
Interventions: BEHAVIORAL: Plans of Action and Care Transitions|BEHAVIORAL: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Aprepitant for the Prevention of Chemotherapy Induced Nausea and Vomiting (CINV)(0869-130)(COMPLETED)
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: aprepitant|DRUG: Comparator: ondansetron|DRUG: Comparator: dexamethasone|DRUG: Comparator: fosaprepitant dimeglumine|DRUG: Comparator; Placebo (unspecified)|DRUG: Comparator; Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris
Status: NOT_YET_RECRUITING
Conditions: Vasospastic Angina
Interventions: DRUG: Vericiguat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial
Status: COMPLETED
Conditions: Subarachnoid Haemorrhage
Interventions: DRUG: placebo|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rapid Salivary Test to Detect SARS-CoV-2 (COVID-19)
Status: COMPLETED
Conditions: COVID-19|SARS-CoV 2|Corona Virus Infection
Interventions: DIAGNOSTIC_TEST: rapid salivary test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study: Investigating Mood Changes After Slow-wave Enhancement
Status: NOT_YET_RECRUITING
Conditions: Depressive Disorder, Major|Depression|Depression, Unipolar|Depressive Disorder
Interventions: DEVICE: Slow-wave enhancement|DEVICE: Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Open-Label Study of Intravitreal ICON-1 in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Choroidal Neovascularization|Wet Macular Degeneration
Interventions: BIOLOGICAL: ICON-1|BIOLOGICAL: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop Glucagon Administration For Hypoglycemia Treatment
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Glucagon-only Bionic Pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Male Infertility: The CBG-study a Randomized Clinical Trial
Status: COMPLETED
Conditions: Male Infertility
Interventions: DRUG: Cholecalciferol and calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injection of Allogenic Lyophilized Growth Factors in Primary Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DRUG: allogenic lyophilized growth factors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Darapladib 160 mg|DRUG: Placebo|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partnership in Safeguarding People With Dementia From Primary and Social Care Perspectives
Status: RECRUITING
Conditions: Dementia|Abuse Client|Neglect; Care, Malnutrition
Interventions: OTHER: Not applicable as not an intervention - PLwD and family/carers|OTHER: Not applicable as not an intervention - HCP's
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Core Stability Exercises With and Without Kinesio-Taping in CP Children
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: combination of core stability exercises and kinesio-taping|OTHER: Core stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MYPHISMO: MYB and PD-1 Immunotherapies Against Multiple Oncologies Trial
Status: COMPLETED
Conditions: Colorectal Cancer|Adenoid Cystic Carcinoma
Interventions: DRUG: TetMYB Vaccine|DRUG: BGB-A317
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helm CPAP Versus Mask CPAP After Major Abdominal Surgery
Status: UNKNOWN
Conditions: Respiratory Insufficiency
Interventions: DEVICE: Continuously helm CPAP|DEVICE: Intermittent Mask CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Single Administration Post-Exposure Prophylaxis Treatment for Ebola Virus
Status: COMPLETED
Conditions: Ebola Hemorrhagic Fever
Interventions: DRUG: Placebo|DRUG: AVI-6002
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of a Flexible Dose of Galantamine Versus Placebo in the Treatment of Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease|Dementia
Interventions: DRUG: galantamine hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Web-Based Education on Self-Care Power, Self-Efficacy, and Quality of Life in Knee Arthroplasty Patients.
Status: RECRUITING
Conditions: Knee Arthroplasty
Interventions: BEHAVIORAL: Web-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection
Status: COMPLETED
Conditions: CS Scar Defect(Niche) How to Avoid
Interventions: PROCEDURE: bladder flap dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Autologous Mesenchymal Stem Cells to Treat Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: BIOLOGICAL: Endobronchial infusion of adult mesenchymal stem cells|BIOLOGICAL: Autologous mesenchymal stem cells derived from bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of FolateScan (Technetium Tc 99m EC20) in Subjects With Pituitary Tumors
Status: COMPLETED
Conditions: Pituitary Tumors
Interventions: DRUG: Technetium Tc 99m EC20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Protective Immune Response to Attenuated Enterotoxigenic Escherichia Coli Infection
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: E. coli strain E1392-75-2A dose 1E10 CFU|BIOLOGICAL: E. coli strain E1392-75-2A dose 1E9 CFU|BIOLOGICAL: E. coli strain E1392-75-2A dose 1E8 CFU|BIOLOGICAL: E. coli strain E1392-75-2A dose 1E7 CFU|BIOLOGICAL: E. coli strain E1392-75-2A dose 1E6 CFU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impedance Cardiography as Tool for Continuous Hemodynamic Monitoring During Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DEVICE: Impedance cardiography|DIAGNOSTIC_TEST: Sensory levels|DIAGNOSTIC_TEST: Motor block|DIAGNOSTIC_TEST: Sensory level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Telephone Support for Advanced Gastrointestinal Cancer Patients and Caregivers
Status: COMPLETED
Conditions: Gastrointestinal Neoplasms
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Education/Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison Between Biodentine and Calcium Hydroxide in the Indirect Pulp Treatment on Primary Teeth
Status: UNKNOWN
Conditions: Dental Caries
Interventions: PROCEDURE: Indirect Pulp Treatment with Bioactive Dentin Substitute|PROCEDURE: Indirect Pulp treatment with Calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Buprenorphine Transdermal Patch in Chinese Subjects With Moderate to Severe Chronic Cancer Pain
Status: UNKNOWN
Conditions: Cancer Pain
Interventions: DRUG: Buprenorphine transdermal patches|DRUG: Morphine Sulfate Sustained-Release Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Veins Circular Ablation Catheter Evaluation for Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: nMARQ catheter|DEVICE: Navistar catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise to Improve Sleep in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Cardiovascular training (CT)|BEHAVIORAL: Resistance training (RT)|BEHAVIORAL: Multimodal training (MT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Palbociclib in Patients With Metastatic Urothelial Cancer After Failure of First-Line Chemotherapy
Status: TERMINATED
Conditions: Metastatic Urothelial Carcinoma (UC)
Interventions: DRUG: Palbociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Masticatory Performance and Patient Satisfaction for Conventional and 3D Printed Implant Overdentures
Status: COMPLETED
Conditions: Patient Satisfaction
Interventions: DEVICE: Dental implant placement|DEVICE: Bar attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: UB-421 in Combination With Optimized Background Regimen in Patients With Multi-drug Resistant HIV-1 Infection
Status: NOT_YET_RECRUITING
Conditions: HIV-1 Infection
Interventions: BIOLOGICAL: UB-421|OTHER: Antiretroviral (ARV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cell Therapy In Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: optimal therapy for cardiaca failure|PROCEDURE: cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Spinal Cord Stimulation After Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Transcutaneous Electrical Spinal Cord Stimulation (TcESCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)
Status: COMPLETED
Conditions: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma|Leukemia, Myeloid, Acute|Burkitt Lymphoma|Lymphoma, B-Cell|Lymphoma, Follicular|Lymphoma, Large B-Cell, Diffuse
Interventions: BIOLOGICAL: Hematopoietic Umbilical Cord Blood Stem Cell Transplantation|BIOLOGICAL: GVHD prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of Child and Parent-Targeted Health Promotion Interventions in Pediatric Stem Cell Transplantation
Status: COMPLETED
Conditions: Bone Marrow|Stem Cell Transplant
Interventions: OTHER: Massage Therapy|OTHER: Humor Therapy|OTHER: Relaxation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease
Status: COMPLETED
Conditions: Graft-versus-host-disease|GVHD|GVHD, Acute
Interventions: DRUG: BMS-986004|DRUG: Sirolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acceptability and Feasibility Study of the Program "Yo Se Lo Que Quiero" (Unplugged)
Status: COMPLETED
Conditions: Substance Use|Adolescent Behavior
Interventions: BEHAVIORAL: "Yo Sé Lo Que Quiero" programl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PhXA41|DRUG: timolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Desensitizing Efficacy of Polymeric Nano Calcium Fluoride Containing Varnish
Status: UNKNOWN
Conditions: Dentin Hypersensitivity
Interventions: COMBINATION_PRODUCT: polymeric nano calcium fluoride containing varnish NANO SEAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Coronary Artery Disease After Mediastinal Irradiation
Status: COMPLETED
Conditions: Radiation Therapy|Coronary Artery Disease|Hodgkin Lymphoma
Interventions: RADIATION: CT coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Anti-pneumococcal Vaccine Strategy in Patients Treated With Immunosuppressants or Biotherapies for CIBD
Status: TERMINATED
Conditions: Infections, Pneumococcal|Bowel Diseases, Inflammatory
Interventions: BIOLOGICAL: Prevenar 13|BIOLOGICAL: Pneumo 23
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pegylated-Interferon and Ribavirin in Hepatitis C Patients With Persistently Normal Alanine Aminotransferase Levels
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peg-Interferon alpha2a plus Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fixed Monthly Dosing of Ranibizumab in Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Wet Macular Degeneration
Interventions: DRUG: Lucentis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study to Assess the Efficacy of Decitabine in the Treatment of Chronic Myelomonocytic Leukemia
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Added Value of Systemic Lidocaine on Postoperative Pain, Opiate Use and Nausea After Knee Arthroscopy
Status: COMPLETED
Conditions: Surgery|Pain, Postoperative|Nausea, Postoperative|Opioid Use
Interventions: DRUG: systemic lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Cannabidiol Oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma
Status: RECRUITING
Conditions: Chordoma|Metastatic Chordoma|Unresectable Chordoma
Interventions: BIOLOGICAL: Cetuximab|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of L-Ornithine L-Aspartate (LOLA) as an Adjunct to Branched Chain Amino Acids (BCAA) Enriched Solutions on Clinical Outcomes in ICU Patients With Hepatic Encephalopathy
Status: RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: DRUG: Branched-chain amino acids (BCAA), enriched solution (Aminoleban) and L-ornithine L-aspartate (LOLA)|DRUG: Branched-chain amino acids (BCAA), enriched solution (Aminoleban)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Protocol Design of Hand Robotics Assisted Therapy in Patients With Different Severity of Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: Amadeo-assisted training-1|DEVICE: Amadeo-assisted training-2|DEVICE: Amadeo-assisted training-3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Dyspnea Relief During Exercise in COPD Patients Following Treatment With Tiotropium (Spiriva)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients
Status: COMPLETED
Conditions: Restless Legs Syndrome (RLS)
Interventions: DRUG: Placebo|DRUG: Gabapentin enacarbil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Amantadine Sulphate on Disorders of Consciousness
Status: ACTIVE_NOT_RECRUITING
Conditions: Amantadine|Consciousness Disorders|Electroencephalography
Interventions: DRUG: Amantadine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess 11 Beta-hydroxysteroid Dehydrogenase Type 1 Inhibition in Adipose Tissue by SPI-62
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus in Obese|Obesity|Type2Diabetes
Interventions: DRUG: SPI-62|DRUG: Cortisone-d8
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
Status: NOT_YET_RECRUITING
Conditions: Water|Child Nutrition|Family Dynamics|Healthy Nutrition|Healthy Lifestyle|Health-Related Behavior|Obesity Prevention
Interventions: BEHAVIORAL: Water is K'é
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Nursing Education Intervention on Women's Health Literacy of Plasticizers
Status: UNKNOWN
Conditions: Endocrine Disrupting Chemicals|Health Literacy
Interventions: BEHAVIORAL: Experimental: nursing education interventions (including e-health platform assistance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Epifaith® Syringe With the Plastic Syringe
Status: NOT_YET_RECRUITING
Conditions: Epidural; Anesthesia, Headache|Analgesia
Interventions: PROCEDURE: Labor analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of a Multi-pronged Intervention to Address Prevention of Violence in Zambia
Status: COMPLETED
Conditions: Domestic Violence|Mental Health Impairment|Child Abuse|Alcoholism
Interventions: BEHAVIORAL: CETA|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia
Status: RECRUITING
Conditions: Skin Cancer|Mucosal Neoplasm of Oral Cavity|Soft Tissue Neoplasm
Interventions: DEVICE: Radiation: Diffusing Alpha Radiation Emitters Therapy (DaRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atogepant for Prophylaxis of Migraine in Participants Who Failed Previous Oral Prophylactic Treatments.
Status: COMPLETED
Conditions: Episodic Migraine
Interventions: DRUG: Atogepant 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain
Status: COMPLETED
Conditions: Opioid Induced Constipation
Interventions: DRUG: Placebo|DRUG: ADL5945 0.1 mg|DRUG: ADL5945 0.25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study Tests a New Medicine Called BI 685509 in Patients That Have Kidney Problems Because of Diabetes. The Study Tests How BI 685509 is Taken up in the Body and How Well it is Tolerated (Multiple Rising Doses)
Status: COMPLETED
Conditions: Diabetic Nephropathies
Interventions: DRUG: BI 685509|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Compare the Safety, Pharmacokinetic Profiles of CJ Amlodipine/Valsartan 10/160mg and Novartis Exforge 10/160mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CJ Amlodipine/Valsartan 10/160mg|DRUG: Novartis Exforge 10/160mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of Talnetant Versus Placebo And Risperidone In Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Talnetant|OTHER: placebo|OTHER: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use Of Liposomal Bupivacaine For Pain Control
Status: COMPLETED
Conditions: Pain, Breast
Interventions: DRUG: Bupivacaine|DRUG: Liposomal Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Expectations on Post-needling Soreness and Pain Processing After Dry Needling Treatment
Status: COMPLETED
Conditions: Placebo Effect|Pain Intensity|Disability|Dry Needling
Interventions: OTHER: Dry Needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of AIDSVAX B/E Vaccine in Intravenous Drug Users in Bangkok, Thailand
Status: COMPLETED
Conditions: HIV Infections|HIV Seronegativity
Interventions: BIOLOGICAL: MN rgp120/HIV-1 and A244 rgp120/HIV-1
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Impact of a Chatbot on COVID-19 Vaccine Perceptions and Intentions in ESPERES Cohort (ESPERES-COVID-19-CHATBOT)
Status: COMPLETED
Conditions: Healthcare Workers|Covid19
Interventions: DEVICE: Chatbot on COVID-19 vaccine hesitancy|OTHER: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Of Rosiglitazone Plus Insulin To Treat Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetes Mellitus, Type 2
Interventions: DRUG: Rosiglitazone 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels
Status: COMPLETED
Conditions: Scoliosis|Kyphosis
Interventions: PROCEDURE: Traditional technique|PROCEDURE: Minimally invasive technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Optimize the Quality of Samples for Cell-mediated Immunity (CMI) in ART-naïve HIV-1-infected Subjects
Status: COMPLETED
Conditions: AIDS|AIDS Vaccines
Interventions: PROCEDURE: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: Prostate|Ejaculation|Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Search retrograde ejaculation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Efficacy of Automated Intermittent Boluses for Continuous Femoral Nerve Block: a Prospective, Randomized Comparison to Continuous Infusions
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee|Nerve Block
Interventions: OTHER: Automated intermittent bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TDCS* and Laterality Trainnning in Patients With Chronic Neck Pain
Status: RECRUITING
Conditions: Neck Pain|Chronic Pain
Interventions: DEVICE: TDCS|DEVICE: Recognize (hand) - Laterality|OTHER: Sham TDCS|OTHER: Landscape recognition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Edaravone Dexborneol for Treatment of Acute Ischemic Stroke With Endovascular Therapy in Extended Time Windows
Status: UNKNOWN
Conditions: Stroke, Ischemic
Interventions: DRUG: Edaravone Dexborneol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Progressive Resistance Training Versus Total Hip Arthroplasty in Patients With Hip Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Osteoarthritis
Interventions: PROCEDURE: Total Hip Arthroplasty|OTHER: Progressive Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dexamethasone Added to the Usual Infiltration With Bupivacaine in Inguinal Hernia Repair Mesh
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine-Dexamethasone|DRUG: Bupivacaine- physiological solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ADVM-022 Intravitreal Gene Therapy for DME
Status: COMPLETED
Conditions: Diabetic Macular Edema|Diabetic Retinopathy
Interventions: BIOLOGICAL: 6E11 vg/eye of ADVM-022|BIOLOGICAL: 2E11 vg/eye of ADVM-022|BIOLOGICAL: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Imaging Agent (I-124 M5A) in Detecting CEA-Positive Liver Metastases in Patients With Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Carcinoma Metastatic in the Liver|Metastatic Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8
Interventions: BIOLOGICAL: Iodine I 124 Monoclonal Antibody M5A|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ropinirole Controlled Release (CR) as an Adjunctive Agent in the Treatment of Major Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Ropinirole CR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: China HeadAche DIsorders RegiStry
Status: NOT_YET_RECRUITING
Conditions: Headache Disorders, Primary|Migraine|New Daily Persistent Headache|Medication Overuse Headache|Tension-Type Headache|Trigeminal Autonomic Cephalalgia
Interventions: BEHAVIORAL: Medicine Overuse Headache/New Daily Persistent Headache|BEHAVIORAL: Chronic Migraine|BEHAVIORAL: Patients with other types of primary headache
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Hematopoietic Cell Transplantation|Oncology
Interventions: OTHER: Pharmacogenomic-guided supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CO2 Laser Revision for Burn Related Donor Site Scars
Status: ACTIVE_NOT_RECRUITING
Conditions: Burn Scar|Scar|Skin Graft Scar
Interventions: PROCEDURE: Fractional CO2 Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of a Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Hib Vaccine in 13-59 Months Old Healthy Children
Status: COMPLETED
Conditions: Haemophilus Influenzae Type b (Hib) Infection
Interventions: BIOLOGICAL: Monovalent glyco-conjugated vaccine against Haemophilus influenzae type b (Hib)|BIOLOGICAL: Tetanus toxoid polysaccharide-conjugated vaccine against Haemophilus influenzae type b (Hib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Sublingual Immunotherapy in Peanut-allergic Children
Status: COMPLETED
Conditions: Food Hypersensitivity
Interventions: DRUG: Peanut SLIT|DRUG: Placebo SLIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EKG Criteria and Identification of Acute Coronary Occlusion
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|STEMI|STEMI - ST Elevation Myocardial Infarction|Acute Coronary Artery Thrombosis (Diagnosis)|NSTEMI - Non-ST Segment Elevation MI|Non-ST Elevation Myocardial Infarction|Non ST Segment Elevation Myocardial Infarction|Non ST Segment Elevation Acute Coronary Syndrome|Non-ST Elevation Myocardial Infarction (nSTEMI)|Non STEMI
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cement Excess at Single Implant Crowns Malmö/Lund
Status: COMPLETED
Conditions: Gingivitis and Periodontal Diseases|Tooth Loss
Interventions: DEVICE: implant crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HKT-500 in Adult Patients With Osteoarthritis (OA) Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: ketoprofen Patch|OTHER: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Milrinone Infusion for VAsospam Treatment in Subarachnoid hemoRrhage
Status: RECRUITING
Conditions: Vasospasm
Interventions: DRUG: Milrinone 1 Mg/mL Solution for Injection|DRUG: Saline solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Creatine and Resistance Exercise Training in People With HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: PROCEDURE: Use of creatine monohydrate (a dietary supplement)|BEHAVIORAL: Progressive resistance exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Compumedics "Somfit" Device
Status: COMPLETED
Conditions: Sleep Apnea
Interventions: DEVICE: Intervention is the validation of a sleep monitoring device (i.e. Somfit) against the gold-standard polysomnograph with electroencephalograph (i.e. the Greal system)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positive Valence System Enhancement Treatment for Anxiety and Depression: Clinical Efficacy and Neural Changes
Status: COMPLETED
Conditions: Anxiety Disorders and Symptoms|Depression
Interventions: BEHAVIORAL: Positive Valence System Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Circulating Cytotoxic Lymphocytes in Endothelial Cell Injury in Systemic Sclerosis
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: OTHER: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Ascorbic Acid on Postoperative Pulmonary Complications in Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Postoperative Pulmonary Complications
Interventions: DRUG: Ascorbic Acid|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Values of the Immune Activation Markers CD38 and HLA-DR and the Ratio CD4/CD8 According to the Delay of Combined AntiRetroviral Therapy (c-ART) Initiation in Primary HIV-infected Patients (PRIMIMMUNO)
Status: COMPLETED
Conditions: HIV-infected Patients
Interventions: BIOLOGICAL: lymphocytes immunophenotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Postmarketing Surveillance Study for Use of Menactra® in the Republic of Korea
Status: COMPLETED
Conditions: Meningitis|Meningococcal Meningitis|Meningococcal Infections
Interventions: BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Clinical Trial of a COVID-19 Vaccine in 18-60 Healthy Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT
Status: RECRUITING
Conditions: Hematologic Malignancy|Older Patients|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: COMBINATION_PRODUCT: venetoclax combining with fludarabine and melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Genomic Population Structure and Phenotype-genotype Variation in ADME Genes in Four Populations
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Phenotyping|GENETIC: Genotyping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Using fMRI Imaging to Evaluate the Effect of NKTR-181 on Brain Activity in Healthy, Non-physically Dependent Recreational Opioid Users.
Status: TERMINATED
Conditions: Moderate to Severe Chronic Pain
Interventions: DRUG: NKTR-181|DRUG: Oxycodone IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Camrelizumab With Chemotherapy in Adults With Medically Inoperable Early Stage NSCLC
Status: RECRUITING
Conditions: Early Stage Non-small Cell Lung Cancer
Interventions: DRUG: Biological: Camrelizumab|DRUG: Pemetrexed|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Training Load With/Out Blood Flow Restriction Training in Rheumatoid Populations
Status: TERMINATED
Conditions: Rheumatoid Arthritis|Myositis|Osteoarthritis|Weakness, Muscle
Interventions: OTHER: Strength Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT