pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma
Status: RECRUITING
Conditions: Metastatic Melanoma
Interventions: DRUG: Pembrolizumab|DRUG: Infliximab|DRUG: Placebo|DRUG: Relatlimab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fever Management in Children With Febrile Neutropenia
Status: RECRUITING
Conditions: Fever
Interventions: PROCEDURE: Control Group (Only Algorithm of Febrile Neutropenia Management)|PROCEDURE: Experimental Group (Algorithm of Febrile Neutropenia Management+Cold Steam)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Comparative Study of Arthroscopic and Open Surgery in Cuistow Procedure
Status: UNKNOWN
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: arthroscopic Cuistow|PROCEDURE: open Cuistow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of EzetimiBe/Rosuvastatin in Diabetic Dislipidemia With Hypertriglyceridaemia
Status: UNKNOWN
Conditions: Endocrine System Diseases|Nutritional and Metabolic Diseases|Diabetes Mellitus, Type 2|Dyslipidemias
Interventions: DRUG: Rosuzet tablet 10/5 mg (Ezetimibe 10 mg/Rosuvastatin 5 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luspatercept and Lenalidomide (L2) in Lower-risk, Non-del(5q) MDS Patients
Status: RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Lenalidomide|DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of VSL#3 on Intestinal Permeability in Pediatric Crohn's Disease
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: DIETARY_SUPPLEMENT: VSL#3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Ischemia-Reperfusion Mediated Cardiac Injury in Subjects Undergoing Coronary Artery Bypass Graft Surgery
Status: TERMINATED
Conditions: Coronary Artery Bypass Surgery
Interventions: DRUG: IK-1001|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 764198 is Processed in the Body
Status: COMPLETED
Conditions: Healthy|Chronic Kidney Disease
Interventions: DRUG: BI 764198
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years
Status: RECRUITING
Conditions: Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Interventions: BIOLOGICAL: ExPEC9V|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004)
Status: COMPLETED
Conditions: Advanced Melanoma
Interventions: DRUG: lenvatinib|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Protein or Carbohydrate Intake on Testosterone Levels and Food Intake in Children and Adolescent Boys
Status: COMPLETED
Conditions: Appetitive Behavior|Pediatric Obesity
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tailored Approaches to Reduce Distress and Improve Self-Management for Veterans With Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Diabetes Distress|Self-Management|Veteran
Interventions: BEHAVIORAL: Cognitive Interview|BEHAVIORAL: Baseline Survey|BEHAVIORAL: Qualitative Interviews|BEHAVIORAL: TARDIS Photo Elicitation|BEHAVIORAL: TARDIS Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block After Video-Assisted Thoracoscopic Surgery
Status: RECRUITING
Conditions: Serratus Anterior Plane Block|Pain, Postoperative|Thoracic Surgery, Video-Assisted|Local Anesthetic
Interventions: PROCEDURE: Serratus Anterior Plan Block with 20 ml|PROCEDURE: Serratus Anterior Plan Block with 30 ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Preoperative Radiosurgery Versus Postoperative Stereotactic Radiotherapy for Resectable Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases, Adult
Interventions: RADIATION: preoperative radiosurgery|RADIATION: postoperative hypofractionated stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/Stapedectomy
Status: RECRUITING
Conditions: Otosclerosis
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinico-biological Data Collection Study of Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Metastasis biopsy|BIOLOGICAL: Biomarkers blood, urine and microbiota samples|BEHAVIORAL: Patient Reported Outcome (PRO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Telisotuzumab vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease
Status: TERMINATED
Conditions: Hematologic Diseases|Anemia, Sickle Cell
Interventions: DRUG: Intravenous Ketorolac|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Doses and Fractionation Schedules in Non-low Risk Ductal Carcinoma In Situ (DCIS) of the Breast
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Ductal, Breast
Interventions: RADIATION: Standard WB fractionation|RADIATION: Shorter WB fractionation|RADIATION: Standard WB fractionation+Boost|RADIATION: Shorter WB fractionation + Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Education in Perimenopausal Women to Promote Self-care and Quality of Life
Status: COMPLETED
Conditions: Perimenopausal Women
Interventions: OTHER: Training health professionals|BEHAVIORAL: Behavioral group intervention|OTHER: Usual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Peri-operative Risk Factors for Surgery Site Infection in Cardiac Surgery
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: PROCEDURE: Sternotomy for coronary artery bypass graft, valvuloplasty, aortic surgery or combined procedures, under extracorporeal circulation or not, in emergency or scheduled.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect Of Vestibular Rehabilitation On Kinesiophobia And Balance With Individuals Who Has Vestibular Hypofunction
Status: COMPLETED
Conditions: Individuals With Vestibular Hypofunction|Individuals Between the Ages of 18-65
Interventions: OTHER: vestibular rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antipsychotics and Risk of Hyperglycemic Emergencies
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder|Diabetes Mellitus, Type 2
Interventions: DRUG: Olanzapine|DRUG: Risperidone|DRUG: atypical antipsychotics (other)|DRUG: typical antipsychotics
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diuretic Response in Advanced Heart Failure: Bolus Intermittent vs Continuous INfusion
Status: COMPLETED
Conditions: Heart Failure NYHA Class III|Heart Failure NYHA Class IV
Interventions: DRUG: Loop Diuretics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trial of Perioperative Tadalafil and Influenza Vaccination in Cancer Patients Undergoing Major Surgical Resection of a Primary Abdominal Malignancy
Status: COMPLETED
Conditions: Abdominal Cancer
Interventions: DRUG: Cialis|BIOLOGICAL: Influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: : Intravascular Injection Rates During Cervical Medial Branch Block
Status: COMPLETED
Conditions: Vascular Complications
Interventions: PROCEDURE: cervical spinal injection with 0.2% ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient and Physician Attitudes About Informed Consent for Emergency Department (ED) Computerized Axial Tomography (CT) Scans
Status: COMPLETED
Conditions: Attitudes About CT Utilization
Interventions: OTHER: Educational session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vaginal Progesterone Supplementation in the Management of Preterm Labor
Status: COMPLETED
Conditions: Preterm Labor
Interventions: DRUG: progesterone|DRUG: Tocolytics|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foot-skin Microbiome and Metabolomics of Pitted Keratolysis
Status: ACTIVE_NOT_RECRUITING
Conditions: Microbial Disease|Metabolomics
Interventions: DRUG: 4%Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Appendectomy
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Single Incision Laparoscopic Appendectomy|PROCEDURE: 3 port laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loaded and Unloaded Magnetic Resonance (MR) Imaging of Meniscus-Cartilage-Trabecular Bone in Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Gait Retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pregabalin and Orofacial Neuropathic Pain
Status: TERMINATED
Conditions: Neuropathic Pain|Orofacial Pain
Interventions: DRUG: pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease|Alzheimer Dementia|Vascular Dementia|Lewy Body Disease|Lewy Body Dementia With Behavioral Disturbance (Disorder)|Dementia, Mixed|Parkinson-Dementia Syndrome|Chronic Traumatic Encephalopathy|Huntington's Dementia|Wernicke Korsakoff Syndrome|Traumatic Brain Injury|Dementia, Multi-Infarct|Autism|Autism Spectrum Disorder|Autistic Behavior|Autistic Disorder, Current or Active State|Cadasil|LATE Limbic-predominant Age-related TDP-43 Encephalopathy
Interventions: PROCEDURE: Intravenous Bone Marrow Stem Cell (BMSC) Fraction|PROCEDURE: Intranasal Topical Bone Marrow Stem Cell (BMSC) Fraction|PROCEDURE: Near Infrared Light
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Costoclavicular and Paracoracoid Approaches to Infraclavicular Brachial Plexus Blocks
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Infraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IBD Strong Peer2Peer for Self-Management of Psychological Distress
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Ulcerative Colitis|Crohn Disease
Interventions: BEHAVIORAL: IBD Strong Peer2Peer|OTHER: Waitlist control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
Status: RECRUITING
Conditions: Gingival Recession|Lack of Keratinized Attached Peri-implant Mucosa|Thin Gingiva
Interventions: PROCEDURE: Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM)|PROCEDURE: Free Gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The EXPLAIN Study: Exploring Plant-Based Meat Analogues for Their Impact on Health
Status: RECRUITING
Conditions: Blood Pressure|Cardiometabolic Health
Interventions: OTHER: Standardized diet with commercially available animal meats (comparator products)|OTHER: Standardized diet with commercially available PBMAs (intervention products)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tarceva (Erlotinib) as First Line Therapy in Participants With Non-Small Cell Lung Cancer Harbouring Epidermal Growth Factor Receptor (EGFR) Mutations
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II, Safety Clinical Trial of DCVAC/PCa and ONCOS-102 in Men With Metastatic Castration-resistant Prostate Cancer
Status: TERMINATED
Conditions: Castration-resistant Prostate Cancer
Interventions: BIOLOGICAL: DCVac/PCa|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings in Kidney Transplant Recipients (HARBOR)
Status: COMPLETED
Conditions: Tomography, Optical Coherence|Kidney Transplantation
Interventions: OTHER: Dynamic full-field optical coherence tomography analysis of kidney transplant biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Strength and Conditioning Training on Functional Performance in Children With Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases
Interventions: OTHER: medical treatment|OTHER: plyometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate Administered in Combination With Pemetrexed Versus Pemetrexed Alone as Second Line Therapy in Patients With Stage IIIB or IV Nonsquamous Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: eribulin mesylate|DRUG: pemetrexed|DRUG: Eribulin mesylate (eribulin; E7389)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Confirmatory Study in Erythropoietic Protoporphyria
Status: COMPLETED
Conditions: Erythropoietic Protoporphyria
Interventions: DRUG: Afamelanotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in NSCLC With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer|Melanoma|Mismatch Repair-Proficient Colorectal Cancer
Interventions: DRUG: entinostat|DRUG: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Pembrolizumab Compared to Placebo in Resected High-risk Stage II Melanoma (MK-3475-716/KEYNOTE-716)
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: BIOLOGICAL: Pembrolizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novum Vitrium® Cervical Cage in Anterior Cervical Discectomy and Fusion
Status: TERMINATED
Conditions: Symptomatic Cervical Disc Disease
Interventions: DEVICE: Novum Vitrium® Cervical Interbody Device|DEVICE: Allograft Ring or Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: AEG35156|DRUG: docetaxel|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Health Program for Older Adults With Subjective Cognitive Decline
Status: RECRUITING
Conditions: Memory Loss (Excluding Dementia)|Healthy Lifestyle|Risk Reduction Behavior
Interventions: BEHAVIORAL: My Healthy Brain 1|BEHAVIORAL: My Healthy Brain 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Torrent's Olmesartan Medoxomil, Amlodipine and Hydrochloride Tablets Under Fasting Conditions.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Torrent's Olmesartan medoxomil, Amlodipine and Hydrochlorothiazide Tablets|DRUG: Tribenzor Tablets of Daichi Sankyo Inc, USA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity
Status: RECRUITING
Conditions: Incomplete Spinal Cord Injury|Spasticity, Muscle
Interventions: BEHAVIORAL: Motor Skill Training (MST)|DEVICE: Transcutaneous Spinal Stimulation (TSS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Moderate vs. Aggressive Treatment With Valsartan + Amlodipine on Patients With Hypertension Uncontrolled by Angiotensin-Receptor Blocker (Herein, ARB) Monotherapy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan and amlodipine|DRUG: valsartan and amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Miracle Mouthwash Plus Hydrocortisone vs Prednisolone Mouth Rinse for Mouth Sores Caused by Everolimus
Status: COMPLETED
Conditions: Stomatitis|Oral Mucositis|Neoplasm of the Breast|Malignant Tumor of Breast
Interventions: DRUG: Miracle Mouthwash Plus Hydrocortisone|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lapatinib in Treating Patients With Locally Advanced or Metastatic Biliary Tract or Liver Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Versus PDT for Presumed Ocular Histoplasmosis
Status: UNKNOWN
Conditions: Presumed Ocular Histoplasmosis (POHS)
Interventions: DRUG: ranibizumab|DRUG: verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vitespen (HSPPC-96, Oncophage ®) for Immune Response Assessment in Participants With Resectable Renal Cell Carcinoma at Intermediate Risk of Recurrence
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: HSPPC-96
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Peritubal Analgesic Infiltration in Postoperative Pain Following Percutaneous Nephrolithotomy
Status: COMPLETED
Conditions: Renal Stone
Interventions: DRUG: Marcaine Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Ruxolitinib Phosphate in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma|Untreated Chronic Lymphocytic Leukemia
Interventions: DRUG: Ruxolitinib|DRUG: Ruxolitinib Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Normothermic Isolated Limb Infusion (ILI) With Melphalan Plus Buthionine Sulfoximine (BSO) in Patients With Locally Advanced Malignant Melanoma
Status: WITHDRAWN
Conditions: Melanoma (Skin)
Interventions: DRUG: buthionine sulfoximine|DRUG: melphalan|GENETIC: microarray analysis|OTHER: high performance liquid chromatography|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BT062 in Combination With Lenalidomide or Pomalidomide and Dexamethasone in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: BT062 , intravenous administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carboplatin, Paclitaxel, and Bevacizumab in Treating Patients With Locally Recurrent or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: Carboplatin|DRUG: ABI-007
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Utility of Regional Bioimpedance in Chronically Ventilated Patients
Status: WITHDRAWN
Conditions: Chronic Respiratory Failure
Interventions: DEVICE: NiCAS treated|DEVICE: Non NiCAS treated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 1 Study of MGD010 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: MGD010|DRUG: Placebo|BIOLOGICAL: Hepatitis A vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Oral 5-HTP Intake on Urinary 5-HIAA Excretion
Status: TERMINATED
Conditions: Carcinoid Tumors|Neuroendocrine Tumors
Interventions: DRUG: 5-Hydroxy-Tryptamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Healthy Men to Test Whether BI 1015550 Influences the Amount of Midazolam in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1015550|DRUG: midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and High-Dose Melphalan
Status: COMPLETED
Conditions: Myeloma|Stem Cell Transplantation
Interventions: DRUG: Lenalidomide|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Dialyzed Leukocytes Extracts to Treat Paediatric Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Childhood Atopic Dermatitis
Interventions: BIOLOGICAL: Conventional treatment plus DLE|BIOLOGICAL: Conventional treatment plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ABO Blood Group Antibody Elimination by a Combination of Semiselective Immunoadsorption Therapy and Membrane Filtration
Status: COMPLETED
Conditions: Immunology
Interventions: DEVICE: Membrane filtration|DEVICE: Semiselective IA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Assess the Effect of Food on the Pharmacokinetics of YHD1119 in Healthy Volunteers
Status: COMPLETED
Conditions: Peripheral Neuropathic Pain
Interventions: DRUG: YHD1119 300mg|DRUG: YHD1119 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Kinetics, Biodistribution and Repeatability of 11C-BMS-986196 After Intravenous (IV) Administration in Healthy Participants and After Repeat IV Administration in Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: 11C-BMS-986196
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of an Intervention on Vaccine Hesitancy Among Pediatric Nurses and Pediatricians
Status: COMPLETED
Conditions: Vaccination Hesitancy|Pediatric ALL|Presumptive Communication|Motivational Interviewing
Interventions: BEHAVIORAL: Vaccine Confidence: Skills to Promote Vaccination in the Pediatric Consultations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Anlotinib Combined With Docetaxel Versus Docetaxel for Previous Treated Advanced NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Anlotinib combined Docetaxel|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI and CT Scans to Evaluate Invasive Cervical Cancer Before Treating Patients
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: iodinated contrast dye|PROCEDURE: computed tomography|PROCEDURE: magnetic resonance imaging|RADIATION: gadopentetate dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy
Status: RECRUITING
Conditions: Veteran Aged 65 and Older
Interventions: DEVICE: Bright Light Therapy (AYO Glasses)|DEVICE: Bright Light Therapy (AYO Glasses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Pain|Lumbar Disc Herniation|Back Pain|Spinal Diseases|Surgery
Interventions: DIAGNOSTIC_TEST: Paraspinal Mapping and Quantitative Sensory Pain Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of AVN-944 in Patients With Advanced Hematologic Malignancies
Status: COMPLETED
Conditions: Acute Leukemia|Chronic Leukemia|Multiple Myeloma|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Waldenstrom's Macroglobulinemia
Interventions: DRUG: AVN-944 capsules for oral administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study Comparing Tarlatamab and Durvalumab Versus Durvalumab Alone in First-Line Extensive-Stage Small-Cell Lung Cancer (ES-SCLC) Following Platinum, Etoposide and Durvalumab
Status: RECRUITING
Conditions: Extensive-Stage Small-Cell Lung Cancer|Small-Cell Lung Cancer
Interventions: DRUG: Tarlatamab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available
Interventions: DRUG: MSC2156119J
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of VRd-based Regimen Followed by BCMA CAR-T Therapy in Transplant-Ineligible Patients With New-diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: anti-BCMA CAR-T|DRUG: VRd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of Psychological Treatment in Generalized Anxiety
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Implementation - SOTA|BEHAVIORAL: Implementation - Prolonged focus on changes|BEHAVIORAL: Mastery your Anxiety and Worry (MAW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Plasma Injection Versus Surgical Fixation Procedure in Management of Spondylolisthesis grade1.
Status: COMPLETED
Conditions: Degenerative Spondylolisthesis G1
Interventions: OTHER: PRP injection.|PROCEDURE: fixation surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Noninvasive Ventilation on Chronic Obstructive Pulmonary Disease (COPD) Patient Functionality
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: physical training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hierarchical Diagnosis for Adult Diffuse Glioma Based on Deep Learning
Status: RECRUITING
Conditions: Astrocytoma|Glioblastoma Multiforme|Oligodendroglioma
Interventions: DIAGNOSTIC_TEST: multi-parametric magnetic resonance imaging scan|DIAGNOSTIC_TEST: Pathology examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing Interventions to Increase Tdap Acceptance for Non-birthing Partners in Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Non-birthing Partner Vaccination in Pregnancy|Tdap - Tetanus, Diphtheria and Acellular Pertussis Vaccination|Vaccine Exposure During Pregnancy
Interventions: BEHAVIORAL: Education|BIOLOGICAL: Vaccine administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Skeletal Stability of Le Fort I Osteotomy Using Patient-specific Osteosynthesis Compared to Mini-plate Fixation for Patients With Dentofacial Disharmony
Status: UNKNOWN
Conditions: Dentofacial Deformities
Interventions: PROCEDURE: Bimaxillary orthognathic surgery using conventional plates|PROCEDURE: Bimaxillary orthognathic surgery using patient specific plates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder
Status: NOT_YET_RECRUITING
Conditions: PTSD|Post-traumatic Stress Disorder
Interventions: PROCEDURE: Propofol anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Durham Connects RCT Evaluation II
Status: ACTIVE_NOT_RECRUITING
Conditions: Unspecified Child Maltreatment, Suspected|Unspecified Child Maltreatment, Confirmed
Interventions: OTHER: Durham Connects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkers
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Extensive Stage Small Cell Lung Cancer|Limited Stage Small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Recurrent Small Cell Lung Cancer|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: Ponatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PEEK Fixed Retainer
Status: RECRUITING
Conditions: Retention
Interventions: DEVICE: Multistranded stainless steel fixed retainer|DEVICE: Polyether-Ether-Ketone (PEEK) fixed retainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Bi-Axial Rotating Magnetic Field Therapy in Refractory Neuropathic Foot Pain Secondary to Diabetic Peripheral Neuropathy
Status: UNKNOWN
Conditions: Diabetic Neuropathies
Interventions: DEVICE: foot energizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Valuation of the Low Back Pain Treated With Different Types of Active Exercises in Women
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: PROCEDURE: Core Stability Exercises (CSE)|PROCEDURE: Traditional Back School|DEVICE: TENS|DEVICE: Infra-red
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of EUFLEXXA™ for Treatment of Painful Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: EUFLEXXA™|DEVICE: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Sublingual Sufentanil for Acute Pain in the Ambulatory Surgery Center
Status: COMPLETED
Conditions: Pain|Pain, Acute|Anesthesia
Interventions: DRUG: Sublingual Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK1349572 Proton Pump Inhibitor Drug Interaction and Supratherapeutic Dose Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GSK1349572|DRUG: GSK1349572|DRUG: Placebo|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin in the Post-cesarean Pain Management of Buprenorphine Patient
Status: WITHDRAWN
Conditions: Cesarean Delivery|Pain Management
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Family Assessment Motivation, and Linkage Intervention (FAMLI)
Status: COMPLETED
Conditions: Mapping Enhanced Counseling (MEC)|Active Linkage (AL)
Interventions: BEHAVIORAL: Mapping Enhanced Counseling|BEHAVIORAL: Active Linkage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin for the Management of Chronic Orchialgia
Status: COMPLETED
Conditions: Chronic Testicular Pain
Interventions: DRUG: Botox Injection|PROCEDURE: Normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Risk in Digital Osteoarthritis
Status: RECRUITING
Conditions: Osteoarthritis Hand|Lumbago|Osteoporosis|Radiculopathy Lumbar
Interventions: OTHER: Intima media thickness ultrasound|OTHER: hand ultrasound|OTHER: EndoPAT™ 2000 system|OTHER: X-ray absorptiometry (DXA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetics of IAsp Following CSII in Patients With T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin Aspart (IAsp)|DRUG: Insulin Aspart (IAsp).|DRUG: Insulin Aspart (IAsp)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triptorelin in Preventing Early Menopause in Premenopausal Women Who Are Receiving Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: methotrexate|DRUG: paclitaxel|DRUG: triptorelin|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings
Status: COMPLETED
Conditions: HIV Infections|Tuberculosis
Interventions: DRUG: Didanosine|DRUG: Efavirenz|DRUG: Lamivudine|DRUG: Standard TB treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy
Status: TERMINATED
Conditions: Small Fiber Neuropathy|Diabetes Mellitus
Interventions: DRUG: BIIB074|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Brimonidine/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Ocular Hypertension
Interventions: DRUG: brimonidine/timolol fixed combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clarithromycin Resistant Tailored Therapy
Status: COMPLETED
Conditions: Peptic Ulcer|Helicobacter Pylori Infection
Interventions: PROCEDURE: 23S rRNA point mutation test of Helicobacter pylori|PROCEDURE: UBT test & Gastroenterology with biopsy c silver stain
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Cerebrospinal Fluid INflammatory Markers After Addition of Maraviroc to MONotherapy Darunavir/Ritonavir - The CINAMMON Study
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 36-Week Safety Extension Study of ELND005 as a Treatment for Agitation and Aggression in Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Group 1 ELND005|DRUG: Group 2 ELND005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Root Canal Treatment in Primary Molars With Necrotic Pulp Using Two Different Pulp Therapies
Status: COMPLETED
Conditions: Dental Pulp Necrosis
Interventions: DRUG: Pulp Therapy CTZ Paste|DRUG: Pulp Therapy ZOE Paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Root Canal Obturation With Sealer Containing Prednisolone.
Status: COMPLETED
Conditions: Root Canal Obturation
Interventions: DEVICE: root canal sealer : CORTISOMOL SP|DEVICE: root canal sealer : SEALITE REGULAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BCG Vaccination for Healthcare Workers in COVID-19 Pandemic
Status: COMPLETED
Conditions: COVID-19|Sars-CoV2
Interventions: BIOLOGICAL: Bacille Calmette-Guérin (BCG)|OTHER: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DIETARY_SUPPLEMENT: niacinamide|DRUG: carbogen|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Auriculotherapy for Osteoarthritis Knee
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: magnetotherapy|DEVICE: laser auriculotherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers
Status: UNKNOWN
Conditions: Pancreatic Cancer|Colorectal Cancer|Non-small Cell Lung Cancer|KRAS Mutation-Related Tumors
Interventions: DRUG: RMC-4630|DRUG: LY3214996
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability And Efficacy Study Of Topical PF-06763809 In Subjects With Mild To Moderate Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: PF-06763809|OTHER: Vehicle|DRUG: Calcipotriene/calcipotriol|DRUG: Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-Tumoral Vascular Growth Patterns is a Robust Indicator of Adjuvant Therapy Following Liver Resection in HCC
Status: ACTIVE_NOT_RECRUITING
Conditions: HCC|Adjuvant Therapy|Immunotherapy|Recurrence
Interventions: DRUG: Sintilimab|DRUG: Lenvatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glutathione, Oxidative Stress and Mitochondrial Function in COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Glycine|DIETARY_SUPPLEMENT: N-acetylcysteine|DIETARY_SUPPLEMENT: Alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Randomized Study of the Use of Warfarin During Pacemaker or ICD Implantation in Patients Requiring Long Term Anticoagulation
Status: COMPLETED
Conditions: Bradycardia|Tachycardia|Atrial Fibrillation|Valvular Heart Disease
Interventions: DRUG: continue warfarin through the procedure|DRUG: Hold warfarin|DRUG: Warfarin held with heparin transition.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION