pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Anamorelin Hydrochloride, Physical Activity, and Nutritional Counseling in Decreasing Cancer-Related Fatigue in Patients With Incurable Metastatic or Recurrent Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|C-Reactive Protein Measurement|Cancer Fatigue|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Weight Loss
Interventions: DRUG: Anamorelin Hydrochloride|BEHAVIORAL: Exercise Intervention|OTHER: Laboratory Biomarker Analysis|OTHER: Nutritional Assessment|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HFNC Versus Oxygen Face Mask on Postoperative Pulmonery Complications
Status: COMPLETED
Conditions: Post Operative Pulmonary Complications
Interventions: DEVICE: HFNC|DEVICE: Oxygen face mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Accuracy in Resection of Non-pedunculated Colonic Lesions 5-20 mm With/Without Using NBI
Status: TERMINATED
Conditions: Polypectomy
Interventions: DEVICE: NBI during polypectomy|DEVICE: no NBI during polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose Escalation of Lapatinib With Paclitaxel in Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Lapatinib and Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Comparing Talquetamab to Belantamab Mafodotin in Participants With Relapsed/Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Relapsed/ Refractory Multiple Myeloma
Interventions: DRUG: Talquetamab|DRUG: Belantamab Mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SclerFIX Graft in Scleral Thinning After Exeresis of Tumors of the Ocular Surface
Status: RECRUITING
Conditions: Scleral Thinning
Interventions: BIOLOGICAL: SclerFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IO102-IO103 in Combination With Pembrolizumab as First-line Treatment for Patients With Metastatic NSCLC, SCCHN, or mUBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Non Small Cell|Head and Neck Squamous Cell Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: IO102-IO103 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-up of the VIPES Study to Evaluate Efficacy and Safety of Viaskin Peanut in Adults and Children
Status: COMPLETED
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: Viaskin Peanut 250 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Status: TERMINATED
Conditions: Macular Degeneration, Age-Related|Geographic Atrophy
Interventions: DRUG: Galegenimab|DRUG: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) Amyloidosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Light Chain (AL) Amyloidosis, Stage 3B
Interventions: DRUG: Daratumumab|DRUG: Bortezomib Injection|DRUG: Dexamethasone oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sulforaphane on Normal Prostate Tissue
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: High Sulforaphane Extract (Broccoli Sprout Extract)|DRUG: Microcrystalline Cellulose NF (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Aerobic Exercise Training on Nurses' Sleep Quality, Fatigue, Attention and Cortisol Profile
Status: COMPLETED
Conditions: Nurse|Attention|Aerobic Exercise|Sleep Quality|Fatigue|Cortisol
Interventions: BEHAVIORAL: aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Tolerability of a Bioconjugate Vaccine Against Shigella Flexneri 2a
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: Flexyn2a|BIOLOGICAL: Placebo|BIOLOGICAL: Flexyn2a plus adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Recombinant Interferon Gamma in Treating Patients With Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Myxoid Liposarcoma|Round Cell Liposarcoma|Synovial Sarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant Interferon Gamma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Ewing Sarcoma
Interventions: DRUG: Cyclophosphamide|DEVICE: Doxorubicin|DRUG: Vincristine|DRUG: Ifosfamide|DRUG: Etoposide|PROCEDURE: Surgery|RADIATION: Radiation Therapy*|DRUG: Temozolomide|DRUG: Irinotecan|DRUG: Mesna|DRUG: Dexrazoxane|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Benralizumab in Patients With Uncontrolled Asthma on Medium to High Dose Inhaled Corticosteroid Plus LABA (MIRACLE)
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Benralizumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial To Evaluate The Use Of Botox In Breast Reconstruction With Tissue Expanders
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Bilateral mastectomy with reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Dose Escalation Study in Patients With Relapsed or Refractory Waldenstrom's Macroglobulinemia
Status: TERMINATED
Conditions: Waldenstrom's Macroglobulinemia
Interventions: DRUG: IMO-8400
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Truth or Dare; Artificial Blastocoel Collapse Using Laser Before Blastocyst's Vitrification Versus Non-laser Usage
Status: TERMINATED
Conditions: Blastocyst Disintegration
Interventions: DEVICE: laser assisted collapse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Safety and Efficacy Study of New Bifonazol Spray vs Terbinafine Solution vs Placebo
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Bifonazole spray once daily|DRUG: Bifonazole spray twice daily|DRUG: Placebo|DRUG: Placebo|DRUG: Lamisil Once
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of GT267-004 Versus Vancomycin and GT267-004 Versus Metronidazole in Patients With C.Difficile - Associated Diarrhea
Status: COMPLETED
Conditions: Clostridium Enterocolitis|Pseudomembranous Colitis
Interventions: DRUG: tolevamer potassium-sodium (GT267-004)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Evaluation of the Effects of Moderate Hepatic Impairment on Deflazacort Pharmacokinetics
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Deflazacort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Scheduled Triple-lumen Central Venous Catheter Exchange: A Prospective Controlled Randomized Study
Status: TERMINATED
Conditions: Other Female Genital|Cancer
Interventions: PROCEDURE: Placement of a central venous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Imatinib, a Platelet-derived Growth Factor Receptor Inhibitor, and LBH589, a Histone Deacetylase Inhibitor, in the Treatment of Newly Diagnosed and Recurrent Chordoma
Status: UNKNOWN
Conditions: Chordoma
Interventions: DRUG: Imatinib + LBH589
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements
Status: RECRUITING
Conditions: Cirrhosis|Vascular Diseases
Interventions: DEVICE: Endoscopic ultrasound pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypertrophic Cardiomyopathy Symptom Release by BX1514M
Status: COMPLETED
Conditions: Hypertrophic Cardiomyopathy
Interventions: DRUG: Treatment BX1514M|DRUG: Placebo|OTHER: Walk distance test|OTHER: Exercise echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: Aricept (donepezil hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CASIMAS: Catumaxomab Safety Phase IIIb Study With Intraperitoneal Infusion in Patients With Malignant Ascites Due to Epithelial Cancers
Status: COMPLETED
Conditions: Cancer|Neoplasms|Carcinoma|Malignant Ascites
Interventions: DRUG: Catumaxomab|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Coronary Intervention in Patients witH OrthotoPic hEart Transplantation: the PCI-HOPE a Multicenter Study.
Status: UNKNOWN
Conditions: Heart Transplant Failure and Rejection|Coronary Artery Disease
Interventions: OTHER: PCI and implantation drug eluting stent or bare metal stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retreatment With CTL019/CTL119
Status: NOT_YET_RECRUITING
Conditions: Lymphoma, B-Cell
Interventions: DRUG: CD19 redirected autologous T cells (CTL019 or CTL119 cells)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Tidal Volume and EVLWI During OLV
Status: COMPLETED
Conditions: Lung Diseases
Interventions: PROCEDURE: The VT 4 ml/kg group|PROCEDURE: The VT 6 ml/kg group|PROCEDURE: The VT 8 ml/kg group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remifentanil on Cough During Emergence From General Anesthesia : Trial to Compare Between Sevoflurane Anesthesia and Propofol Anesthesia
Status: COMPLETED
Conditions: Elective Thyroidectomy
Interventions: DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial of a Minimal Versus Extended Internet-based Intervention for Problem Drinkers
Status: COMPLETED
Conditions: Alcohol Consumption|Hazardous Alcohol Consumption
Interventions: BEHAVIORAL: Check Your Drinking|BEHAVIORAL: Alcohol Help Centre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental Vaccine for Prevention of Ebola Virus Infection
Status: COMPLETED
Conditions: Ebola Hemorrhagic Fever|Ebola Virus Disease|Ebola Virus Vaccines|Envelope Glycoprotein, Ebola Virus|Filovirus
Interventions: DRUG: VRC-EBOADV018-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Different Gingival Retraction Systems on Gingival Displacement and Periodontal Health
Status: UNKNOWN
Conditions: Gingival Hemorrhage
Interventions: OTHER: No Cord impression material|DEVICE: cord|OTHER: Gingitrac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Role of Tramadol 50mg as an Analgesic During Outpatient Hysteroscopy
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Tramadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multiple-dose Study of Levetiracetam Injection in Japanese and Caucasian Healthy Males
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Multiple 15-minute intravenous infusions of 1500 mg levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Contrast-inDuced nephRotoxicity as Assessed by the KIdney Load-to-DAmage RElationship
Status: COMPLETED
Conditions: Contrast Induced Acute Kidney Injury
Interventions: DRUG: Iobitridol 350|DRUG: Iodixanol 320
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HbA1c Variability in Type II Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Metformin|DRUG: Gliclazide|DRUG: Sitagliptin|DRUG: Liraglutide|DRUG: Pioglitazone|DRUG: Dapagliflozin|DRUG: human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Study the Feasibility and Quality of Life of Medial Group Retropharyngeal Node Sparing in Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: medial group retropharyngeal node（MRLN） sparing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pivotal Study to Evaluate the Safety and Efficacy of GelrinC for Treatment of Cartilage Defects
Status: ACTIVE_NOT_RECRUITING
Conditions: Articular Cartilage Defects in the Knee Joint
Interventions: DEVICE: GelrinC|OTHER: Microfracture historical control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Exposure and Response Prevention(ERP) and SSRIs in Chinese OCD Patients
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Anxiety Disorders|Mental Disorders
Interventions: DRUG: Fluoxetine|DRUG: Sertraline|DRUG: Paroxetine|DRUG: Citalopram|DRUG: Fluvoxamine|BEHAVIORAL: Exposure and Response Prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Doses of Vitamin D and T Regulatory Cells in Preterm Infants
Status: COMPLETED
Conditions: Prematurity|Immune Defect
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Maneuvers for Reducing Post-laparoscopic Pain
Status: COMPLETED
Conditions: Gynecologic Disease
Interventions: PROCEDURE: group C|PROCEDURE: Group L|PROCEDURE: Group LR|PROCEDURE: Group LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing a Low-GI Nutrigenetic and Ketogenic Diet for Weight Loss With 18 Month Follow-up
Status: COMPLETED
Conditions: Weight Loss|Glucose, High Blood|LDL Hyperlipoproteinemia|HDL|Triglycerides High
Interventions: OTHER: weight loss diets
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low-dose Radiotherapy Plus Chemotherapy With Gem-based Doublets and Stereotactic Radiotherapy for Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: RADIATION: LDR|DRUG: Gem-based doublets|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a New Oral Contraceptive Pill on Hormone Related Symptoms Such as Pelvic Pain and Headache
Status: COMPLETED
Conditions: Oral Contraceptive|Headache|Pelvic Pain
Interventions: DRUG: EV/DNG (Qlaira, BAY86-5027)|DRUG: Encapsulated Microgynon + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Same-visit Hepatitis C Testing and Treatment (The QuickStart Study)
Status: RECRUITING
Conditions: Hepatitis C
Interventions: DEVICE: OraQuick HCV Antibody test (OraSure Technologies, Inc)|DEVICE: Xpert HCV Viral Load Finger-stick Point-of-Care test (Cepheid)|DRUG: Sofosbuvir/Velpatasvir (Gilead)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Kinesiophobia After Anterior Cruciate Ligament Reconstruction.
Status: RECRUITING
Conditions: Kinesiophobia|ACL Injury
Interventions: DIAGNOSTIC_TEST: Tampa Scale of Kinesiophobia (TSK-17)|DIAGNOSTIC_TEST: Knee injury and Osteoarthritis Outcome Score (KOOS)|DIAGNOSTIC_TEST: Oxford Knee Score (OKS) scoring|DIAGNOSTIC_TEST: Quadriceps and hamstring muscle isokinetic strength|DIAGNOSTIC_TEST: Single-leg hop test|DIAGNOSTIC_TEST: Y-balance test|DIAGNOSTIC_TEST: Anthropometric measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Wound Packing After Superficial Skin Abscess Drainage
Status: COMPLETED
Conditions: Abscess|Skin Diseases, Infectious|Boils|Furuncle|Carbuncle|Folliculitis|Cellulitis|Wounds
Interventions: PROCEDURE: Wound packing|PROCEDURE: NoPacking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Crotalinae Equine Immune F(ab)2 Antivenom (Anavip) and Crotalidae Polyvalent Immune Fab,
Status: COMPLETED
Conditions: Snake Bite|Blood Coagulation Disorders
Interventions: BIOLOGICAL: Anavip|BIOLOGICAL: CroFab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab or Expectant Observation Following Ipilimumab, Nivolumab, and Surgery in Treating Patients With High Risk Localized, Locoregionally Advanced, or Recurrent Mucosal Melanoma
Status: WITHDRAWN
Conditions: Cervical Carcinoma|Esophageal Carcinoma|Mucosal Melanoma|Mucosal Melanoma of the Head and Neck|Oral Cavity Mucosal Melanoma|Recurrent Melanoma|Stage II Vulvar Cancer AJCC v7|Stage III Vulvar Cancer AJCC v7|Stage IIIA Vulvar Cancer AJCC v7|Stage IIIB Vulvar Cancer AJCC v7|Stage IIIC Vulvar Cancer AJCC v7|Stage IV Oral Cavity Cancer AJCC v6 and v7|Stage IV Vulvar Cancer AJCC v7|Stage IVA Oral Cavity Cancer AJCC v6 and v7|Stage IVB Oral Cavity Cancer AJCC v6 and v7|Stage IVC Oral Cavity Cancer AJCC v6 and v7|Vaginal Carcinoma
Interventions: PROCEDURE: Conventional Surgery|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|OTHER: Patient Observation|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superficial Cervical Plexus Block for Orthognathic Surgery
Status: WITHDRAWN
Conditions: Maxillofacial Injuries|Maxillofacial Trauma|Maxillofacial Abnormalities|Maxillofacial Dysostosis
Interventions: OTHER: Group SCPB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Radiofrequency Ablation and Hepatic Resection for Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: Hepatic resection|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of a Tongue Strength Measurement in the Screening for Sarcopenia in Hospitalized Elderly Patients
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DEVICE: Tongue strength measurement|PROCEDURE: Blood sampling|DIAGNOSTIC_TEST: Mini Mental State Examination (MMSE)|DIAGNOSTIC_TEST: Minimal nutritional assessment (MNA-SF)|DIAGNOSTIC_TEST: Dual-energy x-ray absorptiometry (DEXA)|DEVICE: Dynamometer (Hand grip )|DIAGNOSTIC_TEST: Walking speed
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Intramuscular Electrotransfer of Plasmid AMEP in Patients Suffering From Advanced or Metastatic Melanoma
Status: WITHDRAWN
Conditions: Melanoma
Interventions: BIOLOGICAL: naked DNA coding for protein AMEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Retinal Vessel Pulsations With Electrocardiographic Gating
Status: COMPLETED
Conditions: Vessels; Anomaly
Interventions: DEVICE: Retinal Vessel Analyzer recordings with electrocardiographic (ECG) gating
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders
Status: TERMINATED
Conditions: Hemolytic Disorders|Gallstones
Interventions: DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nonopioid Analgesia After Labral Surgery
Status: RECRUITING
Conditions: Narcotic Use
Interventions: DRUG: Celecoxib|DRUG: Hydrocodone-Acetaminophen|DRUG: Ketorolac|DRUG: Gabapentin|DRUG: Acetaminophen|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Baloxavir in Combination With Oseltamivir in Allogenic Bone Marrow Transplant Recipients With Influenza
Status: TERMINATED
Conditions: Influenza
Interventions: DRUG: Baloxavir Marboxil|DRUG: Placebo|DRUG: Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OKV Versus CKC for Biomechanics and Function in Mild Knee OA Patients
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Aging Problems
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparative Study of Effects of Berry and Grain Products on Postprandial Glycemic Response in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Berry product|OTHER: Bread product|OTHER: Bread product|OTHER: Glucose control solution|OTHER: Glucose-fructose control solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Observational Study Of An Electronic Questionnaire In Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Infections, Bacterial
Interventions: OTHER: GSK questionnaire|OTHER: St. George's Respiratory Questionnaire|OTHER: Acute Short Form 12 version 2|OTHER: Global Efficacy questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Oligodendroglioma|Adult Brain Stem Glioma|Adult Diffuse Astrocytoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Mixed Glioma|Adult Oligodendroglioma|Adult Pilocytic Astrocytoma|Adult Pineal Gland Astrocytoma|Adult Subependymal Giant Cell Astrocytoma|Recurrent Adult Brain Tumor
Interventions: RADIATION: Hyperfractionated radiation therapy|RADIATION: Stereotactic radiosurgery|DRUG: Alisertib|PROCEDURE: Quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Basal Androgens and LH Needing for Ovarian Stimulation for in Vitro Fertilization
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: FSH+LH|DRUG: FSH+LH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Repeated Dosis of Intravitreous Bevacizumab in Uveitic Macular Oedema
Status: TERMINATED
Conditions: Uveitis
Interventions: DRUG: bevacizumab|DRUG: triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of LGH447 in Patients With Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: AML and High Risk MDS
Interventions: DRUG: LGH447|DRUG: LGH447 + midostaurin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Single-blind Placebo Controlled Comparative Trial of Pramipexole and Bromocriptine in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Pramipexole|DRUG: Bromocriptine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation in Spino-Cerebellar Ataxia
Status: COMPLETED
Conditions: Spinocerebellar Ataxia
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Suplementation of Vitamin D in Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Vitamin D3|Gestational Diabetes Mellitus in Pregnancy
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|OTHER: Capsules with placebo (talcum food grade)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Breast Cancer, Advanced Carcinomas With Squamous Cell Histology
Interventions: DRUG: BKM120
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagen Injections for the Treatment of Acne Scars and Wrinkles
Status: TERMINATED
Conditions: Acne Scars|Wrinkles
Interventions: DRUG: Fibroblast Treatment|PROCEDURE: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Reacto- and Immunogenicity of Pneumococcal Conjugate Vaccine When Given as Booster or a 2 Dose Catch up Schedule
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Synflorix|BIOLOGICAL: Infanrix Hexa|BIOLOGICAL: Havrix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of Apremilast in Patients of Chronic and Recurrent Erythema Nodosum Leprosum
Status: COMPLETED
Conditions: Erythema Nodosum Leprosum
Interventions: DRUG: Apremilast;Apremilast;Apremilast 10 MG; 20 MG; 30 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Oncologic Complications|Comprehensive Geriatric Assessment|Vestibular Rehabilitation|Geriatric Oncology|Sarcopenia|Vertigo|Cancer|Rehabilitation|Exercise|Geriatric|Elderly|Frail|Older Adults|Chemotherapy|Chemotherapy-induced Peripheral Neuropathy|Resistance Training|Balance Training|Postural Stability|Pragmatic Trial|Personal Medicine|Individualised
Interventions: OTHER: Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BIOLOGICAL: Albiglutide weekly injection|BIOLOGICAL: Placebo weekly injection|BIOLOGICAL: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacist-led Medication Review With Follow-up on Primary Care Cardiovascular Older Adult Patients.
Status: COMPLETED
Conditions: Cardiovascular Diseases|Medication Adherence|Drug Use|Hypertension|Type 2 Diabetes Mellitus|Dyslipidemias
Interventions: OTHER: Medication review with follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy Study Measuring The Impact Of Treatment With Viagra On The Depressive Symptoms Of Men With Erectile Dysfunction
Status: COMPLETED
Conditions: Impotence|Depression
Interventions: DRUG: Viagra (Sildenafil citrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Locally Prepared Supplement to Support Growth and Brain Health
Status: COMPLETED
Conditions: Malnutrition, Child|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Locally-prepared bar|DIETARY_SUPPLEMENT: USAID Corn Soy Blend Plus|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between IMV and SIMV/PS for Ventilatory Support of Children: a Randomized Clinical Trial
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: PROCEDURE: Intermittent mandatory ventilation (IMV) and synchronous IMV
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Futuros Fuertes 2.0
Status: NOT_YET_RECRUITING
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Control|BEHAVIORAL: Futuros Fuertes 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Music-based VR Intervention for Upper Limb Motor Rehabilitation in Hemiparetic Patients
Status: UNKNOWN
Conditions: Hemiparesis
Interventions: BEHAVIORAL: VR+MUSIC|BEHAVIORAL: VR|BEHAVIORAL: TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Mechanisms of Improved Wound Healing
Status: COMPLETED
Conditions: Burns
Interventions: PROCEDURE: Stable Isotope Infusion study|DRUG: Insulin High Dose|DRUG: oxandrolone|DRUG: Propranolol|DRUG: Growth Hormone|DRUG: Insulin Low Dose|DRUG: IGF-1/IGFBP-3|DRUG: Itraconazole|DRUG: Growth Hormone and Propranolol|DRUG: Oxandrolone and Propranolol|DRUG: Placebo or Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).
Status: TERMINATED
Conditions: Depressive Episodes, Bipolar I Depression
Interventions: DRUG: SEP-4199 CR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab or Nivolumab and Azacitidine in Patients With Recurrent, Resectable Osteosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteosarcoma|Osteosarcoma in Children|Osteosarcoma Recurrent|Sarcoma
Interventions: DRUG: Nivolumab|DRUG: Azacitidine|PROCEDURE: Post Treatment Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity
Status: COMPLETED
Conditions: Metabolic Disease|Obesity|Exercise
Interventions: DIETARY_SUPPLEMENT: Sodium Nitrate|DIETARY_SUPPLEMENT: Beetroot Juice no Nitrate|DIETARY_SUPPLEMENT: Beetroot Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impacts of Omega-3-PUFA Enriched Chicken-meat and Eggs in Healthy Humans
Status: COMPLETED
Conditions: Healthy Diet
Interventions: OTHER: Control Chicken-meat|OTHER: Control Eggs|OTHER: Omega-3-PUFA Enriched Chicken-meat|OTHER: Omega-3PUFA Enriched Eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tramadol-paracetamol Combination in Treatment of Patients Undergoing Spinal Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain, Postoperative
Interventions: PROCEDURE: spine surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Telephone-Based Prevention Care Manager in Increasing Screening Rates for Breast Cancer, Cervical Cancer, and Colorectal Cancer in Minority and Low-Income Women
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer|Colorectal Cancer
Interventions: OTHER: educational intervention|OTHER: study of socioeconomic and demographic variables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effect Of Use Of Raınstick And Kaleydoscope On Paın Anxıety Durıng Blood Draw
Status: COMPLETED
Conditions: Pain|Child, Only|Anxiety|Pain, Procedural
Interventions: OTHER: RAINSTİCK|OTHER: KALEİDOSCOPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation
Status: COMPLETED
Conditions: Renal Transplantation|Heart Transplantation
Interventions: DRUG: Cyclosporine A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine|OTHER: Grapefruit Juice|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Safety and Efficiency of 20w and 30w Holmium Laser Device in Management of 2-3 cm Diameter Kidney Stones With Retrograde Intrarenal Surgery
Status: UNKNOWN
Conditions: Nephrolithiasis
Interventions: PROCEDURE: Retrograde Intrarenal Surgery|PROCEDURE: Retrograde Intrarenal Surgery|PROCEDURE: Retrograde Intrarenal Surgery|DEVICE: Holmium laser device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pediatric Intensive Care Unit Diaries on PICS-p
Status: RECRUITING
Conditions: Post Intensive Care Syndrome|Narrative Medicine|Post Traumatic Stress Disorder|Anxiety|Depression
Interventions: OTHER: PICU diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia
Status: COMPLETED
Conditions: Beta-Thalassemia
Interventions: GENETIC: LentiGlobin BB305 Drug Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Low Cortisol Levels and Whiplash Syndrome
Status: UNKNOWN
Conditions: Injuries, Whiplash
Interventions: DRUG: Hydrocortisone|DRUG: normal saline 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Paracervical Block in Laparoscopic Hysterectomy
Status: UNKNOWN
Conditions: Uterine Fibroid|Adenomyosis
Interventions: DEVICE: Paracervical block|DRUG: 5% bupivacaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Number of Micro-osteo-perforations on the Rate of Tooth Movement.
Status: RECRUITING
Conditions: Orthodontic Tooth Movement
Interventions: PROCEDURE: Micro-osteo-perforations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of AGS-004 During Analytical Treatment Interruption
Status: COMPLETED
Conditions: HIV Infection
Interventions: BIOLOGICAL: AGS-004|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Buspirone in the Treatment of 2-6 Year Old Children With Autistic Disorder
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: DRUG: Buspirone|DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telemedicine in Early Childhood Constraint Therapy in Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: APPLES-tele|BEHAVIORAL: Parent-centered Approach (PCA) Support Intervention|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of MEDI6012 in Acute ST Elevation Myocardial Infarction
Status: COMPLETED
Conditions: ST Elevation Myocardial Infarction
Interventions: BIOLOGICAL: MEDI6012|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I of XKH001Injection in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Adults
Interventions: DRUG: XKH001 Injection|DRUG: XKH001Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Novel Integrative Non-invasive Embryo Selection Approach for in Vitro Fertilization Based on Artificial Intelligence Enhanced Morphokinetic Analysis and Raman Spectra in Spent Culture Media
Status: RECRUITING
Conditions: Reproductive Issues|Subfertility|IVF
Interventions: OTHER: MK-RS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Predicting Aortic Stenosis Progression by Measuring Serum Calcification Propensity
Status: COMPLETED
Conditions: Aortic Valve Sclerosis|Aortic Valve Stenosis|Stenosis Progression|Valvular Heart Disease
Interventions: OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Full-scale Intervention Study: Genetic Risk Communication and Wearables
Status: ACTIVE_NOT_RECRUITING
Conditions: Fitness Trackers|Physical Activity|Exercise|Genetic Predisposition to Disease|Type 2 Diabetes
Interventions: GENETIC: Genetic Risk Estimate|DEVICE: Genetic Risk Estimate + Fitbit Functions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Dose of Ketamine With Low Dose Rocuronium in Children
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: DRUG: Rocuronium|DRUG: ketamine 1|DRUG: ketamine 1.5|DRUG: ketamine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Vidutolimod (CMP-001) in Combination With Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer
Status: SUSPENDED
Conditions: Metastatic Prostate Adenocarcinoma|Stage IV Prostate Cancer AJCC v8
Interventions: DRUG: VLP-encapsulated TLR9 Agonist CMP-001,|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin and Mineral Supplementation Improves Micronutrient Status in Older Adults
Status: COMPLETED
Conditions: Nutrient Deficiency
Interventions: DIETARY_SUPPLEMENT: Pharmavite Nature Made Multi for Him 50+|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment
Status: TERMINATED
Conditions: Adjunctive Treatment of Major Depressive Disorder
Interventions: DRUG: Pimavanserin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions
Status: UNKNOWN
Conditions: White Spot Lesion
Interventions: OTHER: self-assembling peptide|OTHER: nanosilver fluoride varnish|OTHER: sodium fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab, Apatinib Plus HAIC Versus Camrelizumab and Apatinib for HCC With Portal Vein Invasion: a Randomized Trial
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: FOLFOX-HAIC|DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Decision-support Reminders to Improve IPT Initiation Among HIV Positive Adults in Western Kenya
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BEHAVIORAL: TB reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Myocardial Effects of MTP-131 for Reducing Reperfusion Injury in Patients With Acute Coronary Events
Status: COMPLETED
Conditions: Reperfusion Injury|STEMI
Interventions: DRUG: Bendavia (MTP-131)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT