pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Post-Approval Study of the TECNIS SYMFONY® Toric Lenses
Status: COMPLETED
Conditions: Cataract|Corneal Astigmatism
Interventions: DEVICE: Higher Cylinder Toric IOL|DEVICE: Lower Cylinder Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prevention of COVID19 Infection in Nursing Homes by Chemoprophylaxis With Hydroxychloroquine (PREVICHARM)
Status: UNKNOWN
Conditions: Sars-CoV2|Coronavirus Infection|Prevention & Control|Nursing Home|Hydroxychloroquine
Interventions: DRUG: Hydroxychloroquine Only Product in Oral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PET Imaging of Ovarian Carcinoma With 18F-FSPG
Status: WITHDRAWN
Conditions: Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: DRUG: (S)-4-(3-[18F]Fluoropropyl)-L-glutamic acid (18F-FSPG)|PROCEDURE: Positron Emission Tomography|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Falciparum Malaria
Interventions: DRUG: Azithromycin plus chloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III, Randomized, Double-Blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of Nitazoxanide in the Treatment of Uncomplicated Influenza
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Nitazoxanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Influence of Heel Wedge Properties on Roll-over of the Intrepid Dynamic Exoskeletal Orthosis (IDEO)
Status: COMPLETED
Conditions: Physical Disability
Interventions: DEVICE: Heel Cushion Material Bulk (foam)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pregnancy and Childbirth on Pelvic Floor Morphology and Sexual Function in Egyptian Women
Status: COMPLETED
Conditions: Pregnancy, Childbirth and Puerperal Disorders
Interventions: OTHER: postpartum female pelvic floor muscle affection|OTHER: postpartum sexual function in Egyptian women.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Attentional Re-training for Chronic Pain Patients
Status: TERMINATED
Conditions: Chronic Pelvic Perinal Pain
Interventions: OTHER: Group 1|OTHER: Group 2|OTHER: Group 3 (control group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Peri-articular Nerve Group Block Versus Fascia Iliaca Block on Postoperative Pain After Hip Arthroscopy
Status: UNKNOWN
Conditions: Analgesia
Interventions: PROCEDURE: PENG block|PROCEDURE: fascia iliaca block|OTHER: IV analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PANDORA: Delirium Prevention After Cardiac Surgery Using IV Acetaminophen to Prevent Postoperative Delirium in Older Cardiac Surgical Patients
Status: RECRUITING
Conditions: Delirium in Old Age|Delirium|Coronary Artery Disease
Interventions: DRUG: IV acetaminophen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: RHA Redensity - Perioral Rhytids
Status: COMPLETED
Conditions: Perioral Rhytids|Aging|Wrinkle
Interventions: DEVICE: TEOSYAL RHA Redensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph 2 Bortezomib, Dexamethasone, + Doxorubicin With ALCAR for Previously Treated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Bort, Dex, and Dox with ALCAR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell Transplant
Status: RECRUITING
Conditions: Acute Myeloid Leukemia in Children
Interventions: DRUG: CIML NK Cell Infusion|PROCEDURE: CD3+ T Cell Product Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Sugammadex After COVID-19
Status: NOT_YET_RECRUITING
Conditions: General Anesthesia|COVID-19
Interventions: DRUG: Sugammadex Sodium|DRUG: neostigmine 50µg/kg + glycopyrollate 0.01mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROTECT2: Diabetes Care - Eye Exam
Status: UNKNOWN
Conditions: Diabetic Retinopathy|Diabetic Macular Edema
Interventions: BEHAVIORAL: Financial Incentive|BEHAVIORAL: Retinal Care DR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Acral Lentiginous Melanoma|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Mucosal Melanoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of Valproic Acid and Karenitecin for Melanoma
Status: TERMINATED
Conditions: Malignant Melanoma
Interventions: DRUG: Karenitecin|DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms
Status: UNKNOWN
Conditions: Refractory Angina
Interventions: DRUG: Allopurinol 300 MG|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraosseous Administration of Mesenchymal Stromal Cells for Patients With Graft Failure After Allo-HSCT
Status: UNKNOWN
Conditions: Mesenchymal Stem Cell Transplantation
Interventions: BIOLOGICAL: MSC administration (intraosseal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Cancer Disparities Among Latinos in Texas
Status: COMPLETED
Conditions: Psychosocial Problem
Interventions: BEHAVIORAL: Health Education|BEHAVIORAL: Questionnaires|BEHAVIORAL: Telephone Counseling Sessions|DRUG: Nicotine Patches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Cognitive Remediation on Cognition in Young People at Clinical High Risk of Psychosis
Status: COMPLETED
Conditions: Prodromal Schizophrenia
Interventions: OTHER: Cognitive Remediation Therapy|OTHER: computer games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effekt-2 - Efficacy and Safety of Long-term Treatment With KOGENATE® FS in Latin America
Status: COMPLETED
Conditions: Blood Coagulation Disorders|Hemophilia A
Interventions: BIOLOGICAL: Recombinant Factor VIII (Kogenate FS, BAY14-2222)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria
Status: UNKNOWN
Conditions: Bacteriuria
Interventions: DEVICE: Camstent Coated Catheter|DEVICE: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Further Investigation of an Intramuscular Influenza Vaccine (Multimeric-001)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Multimeric-001, 500 mcg|BIOLOGICAL: Adjuvanted PBS|BIOLOGICAL: PBS and TIV 15%|BIOLOGICAL: PBS and TIV 50%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy of Cancer Using Donor Lymphocytes Labelled With In-vitro Bispecific Antibodies.
Status: WITHDRAWN
Conditions: Metastatic Solid Tumors
Interventions: DRUG: Cell therapy with bispecific antibodies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TaiChi-DTx for Treating Long Covid Symptoms
Status: ENROLLING_BY_INVITATION
Conditions: Fatigue|Dyspnea|Cognitive Impairment|Muscle Pain
Interventions: DEVICE: the multi-domain Tai Chi Digital therapy Software Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of DXP604 in Patients With Mild to Moderate COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: DXP604
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability Study of ACT-129968 in Patients With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: ACT-129968|DRUG: Placebo|DRUG: Cetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Chronic Cholecystitis
Interventions: DRUG: Dexmedetomidine and lidocaine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Pediatric Chronic Cholestasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cholestatic Liver Disease
Interventions: OTHER: placebo|COMBINATION_PRODUCT: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Laser Acupuncture on Forearm Bone Mineral Density and Wrist Pain in Osteoporotic Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DRUG: Calcium carbonate|DRUG: Vitamin D3|DEVICE: laser acupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dexmedetomidine in Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Steep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy
Interventions: DRUG: Dexmedetomidine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Soliqua Versus Lantus in Ethnically/Racially Diverse Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Agents
Status: TERMINATED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glargine/Lixisenatide|DRUG: Insulin glargine (HOE901)|DRUG: Background therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SubCutaneous (SC) Versus Intravenous (IV) Granulocyte Colony Stimulating Factors (G-CSF) for the Treatment of Neutropenia in Hospitalized Haemato-oncological Patients
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis|Osteoporosis
Interventions: DRUG: synthetic hPTH 1-34
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Addition Oral Montelukast to Standard Treatment in Acute Asthma in Hospitalized Preschool Children
Status: COMPLETED
Conditions: Acute Asthma|Acute Wheezy Bronchitis
Interventions: DRUG: Montelukast 4 Mg Oral Granule|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of AdCh63 ME-TRAP Alone and With MVA ME-TRAP
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: AdCh63 ME-TRAP|BIOLOGICAL: AdCh63 ME-TRAP; MVA ME-TRAP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study of Pantoprazole Sodium DR Tablets 40 mg of Dr. Reddy's Laboratories Limited Under Fasting Condition
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: Pantoprazole Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method
Status: COMPLETED
Conditions: Arrhythmia, Cardiac|Kidney Cancer|Surgery|Anesthesia, Local
Interventions: DRUG: Bupivacaine-fentanyl|DEVICE: Holter ECG monitor|PROCEDURE: Open kidney cancer surgery|PROCEDURE: General anesthesia|PROCEDURE: Epidural Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Reduction of Daily Maintenance ICS/LABA Treatment Towards Anti-Inflammatory Reliever Treatment in Patients With Severe Eosinophilic Asthma Treated With Benralizumab
Status: COMPLETED
Conditions: Asthma|Severe Eosinophilic Asthma
Interventions: DRUG: Symbicort®|DRUG: Fasenra®|DRUG: Ventolin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: CNS 2a|CNS 2b|CNS 2c|CNS1|Recurrent Adult Acute Myeloid Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|BIOLOGICAL: Filgrastim|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: WEE1 Inhibitor AZD1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aldosterone Antagonism and Microvascular Function
Status: TERMINATED
Conditions: Abdominal Obesity Metabolic Syndrome|Insulin Resistance|Hypertension
Interventions: DRUG: Eplerenone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Niaspan|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intradermal Acupuncture Versus Sham Acupuncture and SSRI for Treating Adolescents With Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRI|DEVICE: SIA|DEVICE: AIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DOX-SL in the Treatment of AIDS-Related Kaposi's Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi|HIV Infections
Interventions: DRUG: Doxorubicin hydrochloride (liposomal)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of XC8, Film-coated Tablets, 40 mg in Patients With Dry Non-productive Cough Against Acute Respiratory Viral Infection
Status: COMPLETED
Conditions: Common Cold|Acute Respiratory Infection|Influenza, Human
Interventions: DRUG: XC8, film-coated tablets, 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Bias Modification for OCD
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Obsessive-compulsive Disorders and Symptoms
Interventions: BEHAVIORAL: Cognitive bias modification for interpretation bias|BEHAVIORAL: Psychoeducation|BEHAVIORAL: Approach avoidance training|BEHAVIORAL: Inactive sham approach avoidance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HAIC Sequential TAE Combined With Lenvatinib and Tislelizumab in Unresectable HCC
Status: COMPLETED
Conditions: Liver Cancer
Interventions: COMBINATION_PRODUCT: HAIC sequential TAE combined with lenvatinib and tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Validation Study of Mobile Virtual Reality-Based Self-Care and Exposure Therapy Contents for the Treatment of Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: PROCEDURE: Arm I (Prepectoral)|OTHER: Arm II (Subpectoral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxygen Supplementation and Ventilator Hyperinflation in the Endotracheal Suction (OSVHES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoventilation|Hypoxemia
Interventions: OTHER: Hyperoxygenation 100% FiO2|OTHER: Hyperoxygenation 20% FiO2|OTHER: Hyperinflation (PEEP- ZEEP) Basal FiO2|OTHER: Hyperinflation (PEEP- ZEEP) 20% FiO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies
Status: TERMINATED
Conditions: Solid Tumor Malignancies
Interventions: BIOLOGICAL: Clostridium novyi-NT spores
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Study of the LRS ThermoSuit™ System in Post Arrest Patients
Status: COMPLETED
Conditions: Cardiac Arrest|Comatose
Interventions: DEVICE: ThermoSuit(R) System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saracatinib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIA Melanoma|Stage IIB Melanoma|Stage IIC Melanoma|Stage IV Melanoma
Interventions: DRUG: saracatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vscan Access R2 Feasibility Evaluation
Status: COMPLETED
Conditions: Gather Feasibility Data and User Feedback on Use of a Device in Vivo on Pregnant Volunteers in Their 2nd and 3rd Trimester
Interventions: DEVICE: GE VScan Access R2 Ultrasound System|DEVICE: GE Corometrics 170 Series Fetal Monitor|DEVICE: GE Corometrics 170 Series Fetal Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Tolerance and Performance (Mode of Administration) of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots
Status: COMPLETED
Conditions: Lentigo Solar|Senile Lentigo
Interventions: DEVICE: Prototypes (816-v1 301) to (816-v1 355) every week|DEVICE: Prototypes (816-v1 301) to (816-v1 355) every two weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Concentrated Bone Marrow Aspirate (cBMA) for Critical Limb Ischemia (CLI)
Status: TERMINATED
Conditions: Critical Limb Ischemia|Peripheral Arterial Disease|Peripheral Vascular Disease
Interventions: DEVICE: Bone marrow concentration device|PROCEDURE: Placebo procedure (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Wound Infusion and Functional Recovery After Colon Surgery
Status: TERMINATED
Conditions: Colon Cancer|Inflammatory Bowel Diseases|Diverticulitis
Interventions: PROCEDURE: Epidural analgesia|PROCEDURE: Wound catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Relation Between Venetoclax Plasma Concentration and Remission in Adults With Acute Myeloid Leukemia (PREDICLAX)
Status: RECRUITING
Conditions: Adult Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Blood sampling for venetoclax drug dosage (venous puncture)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term PK and Safety/Tolerability Testing LDLL600 Against Esmolol in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LDLL600|DRUG: Brevibloc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study of TAH3311 5 mg Oral Dissolving Film vs ELIQUIS® 5 mg Tablet in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers|Fasting|Fed
Interventions: DRUG: Apixaban 5 mg Oral Dissolving Film (TAH3311) and Tablet (Eliquis®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Families and Schools for Health
Status: COMPLETED
Conditions: Overweight|Pediatric Obesity
Interventions: BEHAVIORAL: Family Lifestyle (FL)|BEHAVIORAL: Family Dynamics (FD)|BEHAVIORAL: Peer Group (PG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Spices and Herbs on Endothelial Function
Status: COMPLETED
Conditions: Endothelial Function
Interventions: DIETARY_SUPPLEMENT: Cinnamon|DIETARY_SUPPLEMENT: Oregano|DIETARY_SUPPLEMENT: Ginger|DIETARY_SUPPLEMENT: Rosemary|DIETARY_SUPPLEMENT: Black pepper|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Breast Carcinoma|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Breast Carcinoma|Refractory Breast Carcinoma
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Allogeneic GM-CSF-secreting Breast Cancer Vaccine SV-BR-1-GM|BIOLOGICAL: Pembrolizumab|BIOLOGICAL: Recombinant Interferon Alpha 2b-like Protein|OTHER: Questionnaire Administration|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
Status: UNKNOWN
Conditions: Local Anesthesia
Interventions: DRUG: Buffered Local Anesthesia|DRUG: Conventional Unbuffered Local Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International Multicenter, Observational, Non-Interventional Prospective Study of Azilsartan Medoxomil in Participants With Arterial Hypertension Who Are Overweight or Obese in the Russian Federation and The Republic of Kazakhstan
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Azilsartan Medoxomil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of One Single Dose of SR58611 Compared to Placebo and Paroxetine
Status: COMPLETED
Conditions: Major Depressive Disorders
Interventions: DRUG: amibegron (SR58611A)|DRUG: placebo|DRUG: paroxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma
Status: COMPLETED
Conditions: Adenoid Cystic Carcinoma
Interventions: RADIATION: Radiation|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof-of-Concept Study With BT063 in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: BT063|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of 'Corona-T-test' for Assessment of SARS-COV-2-specific T-cell Response After COVID-19 or Vaccination
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|SARS-CoV-2 Vaccination
Interventions: DIAGNOSTIC_TEST: Corona-T-test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Dose Escalation Study of BAY94-9343 Given by Intravenous Infusion Every 3 Weeks in Japanese Subjects With Advanced Malignancies
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BAY94-9343
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilates Method in People With HAM/TSP
Status: COMPLETED
Conditions: HAM/TSP|HTLV-1 Secondary Myelopathy|Balance|Gait Balance|Functional Mobility
Interventions: OTHER: Pilates Method|OTHER: task-oriented training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BIOMARKER TRIAL of APALUTAMIDE and RADIATION for RECURRENT PROSTATE CANCER
Status: ACTIVE_NOT_RECRUITING
Conditions: PSA Progression|Stage III Prostate Adenocarcinoma|Stage IV Prostate Adenocarcinoma
Interventions: DRUG: Apalutamide|RADIATION: External Beam Radiation Therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pharmacological Interventions on Sleep in Post-Acute Rehabilitation
Status: COMPLETED
Conditions: Sleep Disorders
Interventions: BEHAVIORAL: Nonpharmacological sleep intervention|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synaptic Plasticity in the Epicardial Ganglionated Plexi
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: Parasym|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Standard Dressing Versus Moist Dressing in the Course of the Postoperative Wound in Patients With Knee Prosthesis
Status: UNKNOWN
Conditions: Surgical Wound|Knee Disease
Interventions: PROCEDURE: Multi-Foam dressing|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of HL-085 Combined With Vemurafenib in BRAF V600E Patients With Non-small Cell Lung Cancer: a Phase II Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: HL-085+Vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-Emotio Project A Gamified Preventive School-based Paradigm Using Virtual Reality Technologies for Improving Emotional Regulation in Children and Adolescents.
Status: NOT_YET_RECRUITING
Conditions: Emotional Regulation|Virtual Reality|Anxiety|Depression|Executive Function
Interventions: BEHAVIORAL: VR cognitive training|BEHAVIORAL: VR nature exposure relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Sublingual Tacrolimus in Adult Blood and Marrow Transplant Patients
Status: COMPLETED
Conditions: Immunosuppression|Stem Cell Transplant|Bone Marrow Transplant
Interventions: DRUG: Tacrolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Total Knee Replacement Patients Using the Zimmer-Biomet Persona Total Knee System With Different Inserts
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Knee Osteoarthritis
Interventions: DEVICE: Medial Congruent Insert|DEVICE: Cruciate-Retaining Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Non-invasive Technique of Cerebral Compliance and Auto-regulation Assessment
Status: UNKNOWN
Conditions: Intracranial Hypertension
Interventions: DIAGNOSTIC_TEST: Transcranial Doppler (TCD) ultrasound monitoring|DIAGNOSTIC_TEST: Non invasive intracranial compliance monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of a Long-acting Injectable Antipsychotic vs Clinician's Choice Early in Treatment to Break the Cycle of Relapse in Early Phase Schizophrenics
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Any FDA approved antipsychotic agent|DRUG: aripiprazole long acting injectable formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Compression Device Safety Study on Edema
Status: COMPLETED
Conditions: Edema
Interventions: DEVICE: Prototype device (unnamed) worn-no pressure given (placebo) from inflatable cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs|DEVICE: Prototype device(unnamed)-A battery operated inflatable pneumatic cuffs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: STIMPulseControl Ancillary Speech Study
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Impulse Control Disorder
Interventions: PROCEDURE: bilateral high frequency deep brain stimulation of the subthalamic neucleus combined with best medical treatment according to widely accepted expert consensus paper|DRUG: best medical treatment for management of impulse control in Parkinson´s disease according to widely accepted expert consensus paper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nab-paclitaxel Combined With Bevacizumab in the Treatment of Metastatic Neuroendocrine Carcinoma
Status: UNKNOWN
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Nab-paclitaxel Combined With Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dermatoscopy X400 Interpreted by 6 Non-dermatologists and an Artificial Intelligence Software Skin Artificial Intelligence Versus Dermatoscopy x 20
Status: COMPLETED
Conditions: Genital Tumor|Pigmented Lesions
Interventions: OTHER: Analysis of photos of pigmented tumours by the three groups
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and ECMO
Status: COMPLETED
Conditions: ARDS|Acute Lung Injury|Extracorporeal Membrane Oxygenation|Respiratory Distress Syndrome|Respiratory Tract Diseases|Lung Diseases|Lung Injury, Acute
Interventions: OTHER: Ultra-protective ventilator settings|OTHER: Standard ventilator settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between GLP 1 Analogues and DPP 4 Inhibitors in Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Insulin|DRUG: Sitagliptin|DRUG: Exenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 506U78 In Relapsed Or Refractory Acute Lymphoblastic Leukemia (T-ALL)
Status: COMPLETED
Conditions: T-ALL, T-NHL (Lymphoblastic)
Interventions: DRUG: Nelarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nilotinib Plus Dabrafenib/Trametinib in Metastatic Melanoma
Status: RECRUITING
Conditions: Metastatic Melanoma|BRAF Gene Mutation
Interventions: DRUG: Nilotinib 100mg|DRUG: Nilotinib 200mg|DRUG: Nilotinib 300mg|DRUG: Nilotinib 400mg|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)
Status: COMPLETED
Conditions: Opioid Induced Constipation (OIC)
Interventions: DRUG: placebo|DRUG: NKTR-118
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Chemotherapy Effect|Side Effect of Drug
Interventions: COMBINATION_PRODUCT: Consolidation chemotherapy (4 courses)|COMBINATION_PRODUCT: Concurrent chemotherapy (2 courses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Stem Cell Transplantation in Chronic Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Chronic Lymphocytic Leukemia
Interventions: PROCEDURE: allogeneic stem cell transplantation|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy
Status: TERMINATED
Conditions: Kidney Cancer|Leukemia|Lymphoma|Multiple Myeloma|Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine|DRUG: mycophenolate mofetil|PROCEDURE: stem cell transplantation|RADIATION: total body irradiation|DRUG: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-CHEC-uP: Scaling up an Efficacious Cancer Screening Intervention for Women With Limited English
Status: COMPLETED
Conditions: Breast Cancer|Cervical Cancer
Interventions: BEHAVIORAL: e-CHEC-uP|BEHAVIORAL: CHEC-uP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Long-Term Evaluation of BIIB067 (Tofersen)
Status: COMPLETED
Conditions: ALS Caused by Superoxide Dismutase 1 (SOD1) Mutation
Interventions: DRUG: Tofersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0423 Pemetrexed Disodium in Treating Patients With Recurrent and Unresectable or Metastatic Chondrosarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: pemetrexed disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis
Status: TERMINATED
Conditions: Psoriasis|Eczema
Interventions: DRUG: Neuroskin Forte|DRUG: Placebo Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etodolac and Post-bleaching Sensitivity
Status: COMPLETED
Conditions: Medicaments Substances in Therapeutic Use
Interventions: DRUG: Etodolac|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Sirolimus Eluting Coronary Stent System (Biomime)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy of PRP Combined With Different Hyaluronan for the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: PRP+Artz group|COMBINATION_PRODUCT: PRP+ HYAJOINT Plus group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing BCI-FIT: Brain Computer Interface - Functional Implementation Toolkit
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Brainstem Stroke|Muscular Dystrophies|Parkinson's Disease and Parkinsonism|Multiple System Atrophy|Brain Tumor Adult|Spinal Cord Injuries|Locked-in Syndrome
Interventions: BEHAVIORAL: BCI-FIT multi-modal access|BEHAVIORAL: BCI-FIT adaptive signal modeling|BEHAVIORAL: BCI-FIT active querying|BEHAVIORAL: BCI-FIT language modeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Different Dose of Anti-T Lymphocyte Globulin (ATLG) in Haploidentical HSCT for GVHD Prophylaxis
Status: NOT_YET_RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DRUG: ATLG|DRUG: ATLG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients
Status: NOT_YET_RECRUITING
Conditions: Urinary Tract Infection, Recurrent
Interventions: DRUG: phage therapy|DRUG: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Assessment and CLInical imPlication of Functional tricuSpid rEgurgitation in Heart Failure With Reduced or Preserved Ejection Fraction
Status: RECRUITING
Conditions: Functional Tricuspid Regurgitation
Interventions: DIAGNOSTIC_TEST: Transthoracic Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Selective Strengthening of Peroneus Longus on Pain , Joint Alignment and Foot Function in Hallux Valgus
Status: RECRUITING
Conditions: Hallux Valgus
Interventions: OTHER: Selective Peroneus longus excercise|OTHER: Conventional physical therapy programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Unilateral GPi vs Unilateral STN DBS in the Same Patient With PD
Status: COMPLETED
Conditions: Parkinson Disease|Deep Brain Stimulation|Globus Pallidus Interna|Subthalamic Nucleus
Interventions: PROCEDURE: DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humanalbumin, Hydroxyethylstarch and Ringer Lactate During Cardiac Surgery
Status: COMPLETED
Conditions: Valvular Heart Disease|Coronary Artery Disease
Interventions: DRUG: volume replacement|DRUG: Humanalbumin 5%|DRUG: volume replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: AZD9668|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Delirium|Postoperative Cognitive Dysfunction|Chronic Post-surgical Pain
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud's Disease|Scleroderma|Autoimmune Diseases
Interventions: DRUG: Topical AmphiMatrix with nitroglycerin (MQX-503)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Alogliptin|DRUG: Placebo to alogliptin|DRUG: Metformin|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Erythromycin Before Endoscopy of Patients With Subtotal Gastrectomy (STG), High Risk of Gastric Stasis
Status: COMPLETED
Conditions: Subtotal Gastrectomy|Stomach Cancer
Interventions: DRUG: Erythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment
Status: WITHDRAWN
Conditions: Hepatitis B, Chronic
Interventions: OTHER: Entecavir (ETV)|OTHER: Tenofovir Disoproxil Fumarate (TDF)|OTHER: Tenofovir Alafenamide (TAF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fluorescence Cystoscopy and Optimized MMC in Recurrent Bladder Cancer (FinnBladder 9)
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: PROCEDURE: white light TUR-BT|PROCEDURE: blue light TUR-BT|DRUG: optimized MMC|DRUG: single immediate chemotherapy instillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT