pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nephroprotective Effects of Carnitine and (PDE5) Inhibitor Agent Against Contrast Media-induced Nephropathy (CMN)
Status: UNKNOWN
Conditions: Contrast Media Induced Nephropathy
Interventions: DRUG: Acetylcysteine, Phosphodiesterase type 5 inhibitor ,Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dimensional Approach to Evaluate Reward Processing in Major Depressive Disorder Pre- and Post-Desvenlafaxine Treatment
Status: COMPLETED
Conditions: Depression|Anhedonia
Interventions: DRUG: Desvenlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparative Study Between Laryngeal Mask Airway and Magensium Sulphate in Attenuating Systemic Stress Response During Emergence of Patients Undergoing Supratentorial Tumours.
Status: COMPLETED
Conditions: LMA Versus Mgso4 in Attenuating Stress Response During Emergence of Supratentorial Tumours Patients
Interventions: DEVICE: Laryngeal mask airway|DRUG: Magensium sulphate|OTHER: Control group (closure of anesthetics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Patient and Caregiver Education After Stroke
Status: COMPLETED
Conditions: Stroke, Acute|Stroke, Ischemic|Stroke
Interventions: BEHAVIORAL: Customized education|BEHAVIORAL: Standard of care discharge education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving the Efficacy of Exposure Therapy for the Treatment of Cockroach Phobia
Status: RECRUITING
Conditions: Specific Phobia, Animal
Interventions: BEHAVIORAL: Projection-based augmented reality therapy (P-ARET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Psychological Intervention on Mental Health and Sleep.
Status: ENROLLING_BY_INVITATION
Conditions: Insomnia Chronic|Anxiety|Depression|Sleep Quality|Life Quality
Interventions: BEHAVIORAL: Brief Behavioral Intervention in Insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Care of Intubated Intensive Care Patient
Status: COMPLETED
Conditions: Pneumonia|Mechanical Ventilation Complication|Salivation|Dry Mouth
Interventions: OTHER: oral care bundle|OTHER: clinical oral care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination for 12 Weeks in Adults With Chronic HCV Infection and Compensated Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer Dementia
Interventions: DRUG: Allopregnanolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spacing Lidcombe Program Clinic Visits
Status: UNKNOWN
Conditions: Stuttering
Interventions: BEHAVIORAL: The Lidcombe Program for early stuttering|BEHAVIORAL: The Lidcombe Program for early stuttering|BEHAVIORAL: The Lidcombe Program for early stuttering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Partial Oral Antibiotic Treatment for Bacterial Brain Abscess
Status: RECRUITING
Conditions: Brain Abscess|Cerebral Abscess
Interventions: DRUG: Early transition to oral antibiotics|DRUG: Standard treatment of intravenous antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Porphyromonas Gingivalis Fimbrial Subunit Genotype in Smokers and Nonsmokers After Periodontal Therapy
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Periodontal treatment|PROCEDURE: Microbiological collect|PROCEDURE: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pre-operative PET-MR of High Risk Prostate Cancer Patients for Assessment of Cancer Aggressiveness and Lymph Node Status
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: PROCEDURE: PET-MR 18f-FACBC|PROCEDURE: histology (gold standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Study for Children and Adolescents With Acute Promyelocitic Leukemia
Status: UNKNOWN
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: ATRA|DRUG: ATRA + IDA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ATN-103|DRUG: ATN-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linaclotide Acetate in Preventing Colorectal Cancer in Healthy Volunteers
Status: COMPLETED
Conditions: Colorectal Cancer|Healthy, no Evidence of Disease
Interventions: DRUG: linaclotide acetate|OTHER: placebo|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK525762 in Subjects With NUT Midline Carcinoma (NMC) and Other Cancers
Status: COMPLETED
Conditions: Carcinoma, Midline
Interventions: DRUG: GSK525762
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Three Dimensional (3D) Ultrasound in Predicting Response to Breast Cancer Therapies
Status: COMPLETED
Conditions: Breast Cancers
Interventions: PROCEDURE: Ultrasound Scan|PROCEDURE: Mammography and Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Double-blind, Randomized, Controlled Trial of Quetiapine Versus Haloperidol for the Treatment of Delirium
Status: TERMINATED
Conditions: Delirium
Interventions: DRUG: quetiapine|DRUG: haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Benefit of Laparoscopic Hysterectomy With Less Than 3 Millimeter Diameter's Instruments in Current Practice
Status: UNKNOWN
Conditions: Benign Uterine Diseases
Interventions: PROCEDURE: laparoscopic hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers
Status: UNKNOWN
Conditions: Respiratory Depression|Cannabis Use|Opioid Use
Interventions: DRUG: Medicinal cannabis in combination with oxycodon|DRUG: Medicinal cannabis in combination with placebo oxycodon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Oxytocin Effectiveness in First Trimester Dilatation and Curettage
Status: NOT_YET_RECRUITING
Conditions: Missed Abortion
Interventions: DRUG: Oxytocin|DRUG: Sodium Chloride 0.9% Inj
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Coronary Angiography THerapeutic Virtual Reality
Status: WITHDRAWN
Conditions: Virtual Reality|Atherosclerosis|Coronary Artery Disease|Anxiety|Pain, Acute|Vasospasm;Peripheral
Interventions: DEVICE: Virtual Reality|DRUG: Fentanyl Injection|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health Services for Foster and Adopted Children
Status: COMPLETED
Conditions: Problem Behaviors|Attention Deficit Hyperactivity Disorder|Depression
Interventions: BEHAVIORAL: Attachment and Biobehavioral Catch-up|BEHAVIORAL: Developmental Education for Families
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ELobectomy for NSCLC by VATS Versus Thoracotomy (ECTOP-1007)
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: VATS|PROCEDURE: Thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Apalutamide, Radiotherapy, and LHRH Agonist in Prostate Cancer Patients After Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Apalutamide|RADIATION: Salvage radiotherapy (SRT)|DRUG: Luteinising Hormone Releasing Hormone agonist (LHRHa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Topical Vancomycin in Reducing Infections in Hip and Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Rheumatoid Arthritis|Avascular Necrosis of Hip
Interventions: PROCEDURE: 1.0 g Vancomycin powder into the wound|PROCEDURE: 0,35% povidone-iodine solution lavage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal and Sub-serratus Block
Status: COMPLETED
Conditions: Rhomboid Intercostal Block
Interventions: PROCEDURE: Patients will be received rhomboid intercostal block under ultrasound guidance.|DRUG: conventional intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine
Status: COMPLETED
Conditions: Tumor|Pain
Interventions: DRUG: Tapentadol Extended Release|DRUG: Matching Placebo after Tapentadol in the Titration Phase.|DRUG: Morphine Sulphate Controlled Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rationale and Analysis of the Use of ETDNO in the Treatment of PIPJ Flexion Contracture:
Status: COMPLETED
Conditions: Flexion Contracture of Proximal Interphalangeal Joint|Joint Deformities, Acquired
Interventions: DEVICE: ETDNO (Elastic Tension digital neoprene orthosis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised-controlled Trial of an Oral Microbiome Immunity Formula in Recovered COVID-19 Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19|Probiotic
Interventions: DIETARY_SUPPLEMENT: Microbiome immunity formula|DIETARY_SUPPLEMENT: Active placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Of Adjunctive Treatment Of Cognitive Deficits In Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: PF-3463275|DRUG: PF-3463275|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2944876 in Healthy Japanese and Non-Japanese Participants
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: LY2944876|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Lobeline in Treating Symptoms of ADHD in Adult Patients
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Lobeline sulfate|DRUG: Methylphenidate HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Effects on Pulmonary Haemodynamics and Gas Exchange in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Pulmonary Hypertension
Interventions: DRUG: Sildenafil|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Effect of Food on Pharmacokinetics(PK), Phase I Clinical Study of LCB01-0371
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LCB01-0371 Tablet 800 mg(R)|DRUG: LCB01-0371 Tablet 800 mg(T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study on the Improvement of Sleep Quality, Skin Condition and Life Status After Taking Sleep Aid Drinks
Status: COMPLETED
Conditions: Sleep Disorder
Interventions: COMBINATION_PRODUCT: Drinks with active ingredients such as poria and GABA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Study on the Safety, Anti-tumor Activity and Pharmacology of IPH2101 Combined With Lenalidomide in Patients With Multiple Myeloma Experiencing a First or Second Relapse
Status: COMPLETED
Conditions: Patients With Multiple Myeloma Experiencing a|First or Second Relapse
Interventions: DRUG: IPH2101 combined to lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral GLP-1 on Glucose Homeostasis and Appetite Profile in Healthy Male Subjects
Status: COMPLETED
Conditions: Glucose Homeostasis
Interventions: DRUG: Oral GLP-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study to Assess the Safety of Inactivated Split Influenza Vaccine and Control Vaccine in Korean Volunteer
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: IL-YANG FLU Vaccine Prefilled Syringe INJ.|BIOLOGICAL: Fluarix Prefilled Syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulsed Electromagnetic Fields for Post-Amputation Pain
Status: COMPLETED
Conditions: Phantom Limb Pain|Residual Limb Pain
Interventions: DEVICE: Active then Sham Treatment|DEVICE: Sham then Active Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Doses Study of SHR4640 in Male Subjects With High Serum Uric Acid Level
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: SHR4640
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Assessment of Progression of Paroxysmal AF After CABG
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation, Coronary Artery Disease
Interventions: PROCEDURE: CABG+Pulmonary vein isolation procedure|PROCEDURE: Isolated CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania
Status: UNKNOWN
Conditions: Malaria,Falciparum|Anemia
Interventions: DRUG: Dihydroartemisinin-piperaquine|DRUG: Artesunate-amodiaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Perioperative Use of a Selective COX2 Inhibitor in Patients Undergoing Elective Colorectal Surgery: the Effect on Post-operative Bowel Motility and Post-operative Pain
Status: UNKNOWN
Conditions: Prevention of Post Operative Ileus
Interventions: DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Muscle Relaxants on Efficacy of LMA Insertion
Status: COMPLETED
Conditions: Anesthesia Intubation Complication
Interventions: DRUG: rocuronium|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extracorporeal Cytokine Adsorption in Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass
Interventions: DEVICE: CytoSorb|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of PG102, a Water Soluble Extract From Actinidia Arguta, on Serum Total IgE Levels
Status: COMPLETED
Conditions: Asymptomatic Subjects With Atopy and Elevated Serum IgE
Interventions: DIETARY_SUPPLEMENT: PG102, a water soluble extract from Actinidia arguta|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Acetaminophen Intravenous|DRUG: Acetaminophen Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Protective Effect of Soluble Beta-1,3/1,6-Glucan Compared to Placebo in Oral Mucositis in Head and Neck Cancer Patients
Status: COMPLETED
Conditions: Oral Mucositis
Interventions: DRUG: Soluble beta-1,3/1,6-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Vaping Ethanol in the Evaluation of Impairment
Status: COMPLETED
Conditions: Electronic Cigarette Use
Interventions: OTHER: E-cigarette liquid with ethanol, 1 puff|OTHER: E-cigarette liquid without ethanol, 1 puff|OTHER: E-cigarette liquid with ethanol, 10 puffs|OTHER: E-cigarette liquid without ethanol, 10 puffs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Hot Water Application in Pregnant Women With Restless Legs Syndrome: A Randomised Controlled Study
Status: COMPLETED
Conditions: Restless Legs Syndrome|Pregnancy Related
Interventions: OTHER: Hot water application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptability of Simultaneous Screening for Viral Hepatitis B, C and HIV Among Drug Users in Non-conventional Structures
Status: RECRUITING
Conditions: Hepatitis C|Transmission, Intravenous Drug Abuser|Addiction, Alcohol|Addiction Opiate|Hepatitis C Virus Infection, Response to Therapy of
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Escalation and Expansion Study of TRX518 in Combination With Cyclophosphamide Plus Avelumab in Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors|Advanced Triple Negative Breast Cancer|Advanced Hormone Receptor Positive/Endocrine Refractory Breast Cancer|Advanced Metastatic Castration-Resistant Prostate Cancer|Advanced Platinum-Resistant Ovarian Cancer
Interventions: DRUG: TRX518|DRUG: Cyclophosphamide|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Cancer Prevention Study(CHICAPS)
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervical Cancer|Cervical Neoplasm|Cervical Dysplasia|Human Papillomavirus
Interventions: PROCEDURE: cryotherapy|PROCEDURE: Colposcopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Addition of a Pilates Program for Short-Term Improvements in Patients With Spondylolysis or Spondylolisthesis
Status: COMPLETED
Conditions: Spondylolisthesis|Spondylolysis|Children
Interventions: OTHER: Motor Control|OTHER: General Strengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)
Status: RECRUITING
Conditions: Systemic Sclerosis|Scleroderma
Interventions: COMBINATION_PRODUCT: Anifrolumab (blinded)|DRUG: Placebo (blinded)|COMBINATION_PRODUCT: Anifrolumab (unblinded, open label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indomethacin Prior to Difficult Embryo Transfer is it a Solution?
Status: COMPLETED
Conditions: Difficult Embryo Transfer
Interventions: DRUG: Indomethacin 100Mg Suppository|PROCEDURE: IVF/ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex
Status: COMPLETED
Conditions: Urinary Retention Postoperative|Laparoscopic Cholecystectomy|Neuromuscular Blockade|Sugammadex|Neostigmine|Neuromuscular Blocking Agents|Physiological Effects of Drugs
Interventions: DRUG: Neostigmine|DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma
Status: COMPLETED
Conditions: Prolymphocytic Leukemia|Recurrent Adult Hodgkin Lymphoma|Recurrent Childhood Hodgkin Lymphoma|Recurrent Childhood Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Non-Hodgkin Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory Small Lymphocytic Lymphoma|T-Cell Chronic Lymphocytic Leukemia|T-Cell Prolymphocytic Leukemia
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|PROCEDURE: Autologous-Allogeneic Tandem Hematopoietic Stem Cell Transplantation|DRUG: Carmustine|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Cytarabine|DRUG: Etoposide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Melphalan|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|BIOLOGICAL: Therapeutic Autologous Lymphocytes|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INfusion VErsus STimulation in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Continuous intrajejunal infusion of levodopa-carbidopa|DEVICE: deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Walkers in Infancy and Musculoskeletal System
Status: COMPLETED
Conditions: Use of a Walker in Infancy|Physical Activity Level|Musculoskeletal Problems
Interventions: DIAGNOSTIC_TEST: Posture Analysis|DIAGNOSTIC_TEST: Physical activity level|DIAGNOSTIC_TEST: Muscle strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Osimertinib and Bevacizumab as Treatment for EGFR-mutant Lung Cancers
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|EGFR-mutant Lung Cancers
Interventions: DRUG: osimertinib|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effect of Co-administration of ABT-450 With Ritonavir (ABT-450/r) and ABT-267 in Adults With Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: ABT-450/r|DRUG: ABT-267|DRUG: Ribavirin (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture Regulates Default Mode Network of Chronic Insomnia Disorder Patients : A fMRI Study
Status: UNKNOWN
Conditions: Chronic Insomnia
Interventions: DEVICE: Ture acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Ultrasound Guided Superficial Cervical Plexus Block After Thyroid Surgery
Status: UNKNOWN
Conditions: Bilateral Ultrasound Guided Superficial Cervical Plexus Block|Thyroid Surgery|Enhanced Recovery
Interventions: PROCEDURE: Ultrasound-guided Bilateral superficial cervical plexus block|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nilotinib in Preventing Paclitaxel-Induced Peripheral Neuropathy in Patients With Stage I-III Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: DRUG: Nilotinib|DRUG: Nilotinib Hydrochloride Monohydrate|DRUG: Paclitaxel|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Identification of Optimal Ultrasonografic Tecniques for Determining the Location , Size and the Surgical Methods of Intestinal Endometriotric Nodules
Status: UNKNOWN
Conditions: ULTRASONOGRAPHY|Endometriosis, Rectum
Interventions: DIAGNOSTIC_TEST: Ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of Kedbumin 25% Versus Normal Saline in the Treatment of Post-Surgical Hypovolemia in Pediatric Patients
Status: TERMINATED
Conditions: Hypovolemia
Interventions: DRUG: Kedbumin 25%|DRUG: Normal Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis B
Status: TERMINATED
Conditions: Chronic Hepatitis b
Interventions: DRUG: STSG-0002 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EOI Block Versus ESP Block in Laparoscopic Bariatric Surgery
Status: RECRUITING
Conditions: Anesthesia|Bariatric Surgery Candidate|Regional Anesthesia Morbidity
Interventions: PROCEDURE: Ultrasound guided EOI block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Disorders
Interventions: DRUG: Placebo|DRUG: JNJ-42847922, 5 mg|DRUG: JNJ-42847922, 10 mg|DRUG: JNJ-42847922, 20 mg|DRUG: Zolpidem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Clinical Cohort Study of Modified Flexible Fixation Latarjet Procedure for Recurrent Shoulder Dislocation
Status: NOT_YET_RECRUITING
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: Arthroscopic modified individualized flexible Latarjet procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in the Etiology of Idiopathic Intracranial Hypertension
Status: RECRUITING
Conditions: Idiopathic Intracranial Hypertension
Interventions: PROCEDURE: Blood punction|PROCEDURE: Central blood sampling|PROCEDURE: Intracranial pressure measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment Outcomes of Pulpotomy vs. Pulpectomy in Vital Primary Molars With Symptomatic Irreversible Pulpitis
Status: NOT_YET_RECRUITING
Conditions: Irreversible Pulpitis
Interventions: PROCEDURE: Pulpotomy|PROCEDURE: Pulpectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials
Status: COMPLETED
Conditions: Diet Intervention
Interventions: DIETARY_SUPPLEMENT: Almonds|DIETARY_SUPPLEMENT: Graham crackers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention to Prevent Peer Violence & Depressive Symptoms Among At-Risk Adolescents
Status: RECRUITING
Conditions: Depressive Disorder|Violence
Interventions: BEHAVIORAL: + Brief ED Intervention (BI)|BEHAVIORAL: + Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Research Investigating Depression Effects on Neuroimmune Targets (TRIDENT)
Status: RECRUITING
Conditions: Depression|HIV-1-infection|Inflammation
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy for Adherence and Depression (CBT-AD)|BEHAVIORAL: Antiretroviral Therapy (ART) Adherence Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Pharmacogenetic Study of Ondansetron in Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Ondansetron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Oesophagitis In Adult Patients
Status: COMPLETED
Conditions: Oesophagitis, Eosinophilic
Interventions: DRUG: mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Chirocaine %0.5|DRUG: Chirocaine Heavy 40|DRUG: Chirocaine Heavy 60|DRUG: Chirocaine Heavy 80
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotics on Hyperuricemia
Status: UNKNOWN
Conditions: Subjects With Hyperuricemia
Interventions: DIETARY_SUPPLEMENT: anserine|DIETARY_SUPPLEMENT: Sunflower peptide|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study
Status: UNKNOWN
Conditions: Depression|Pain
Interventions: DRUG: Paroxetine|DRUG: Paroxetin placebo|DRUG: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Solifenacin Succinate as Adjuvant Therapy for Urinary Tract Infection in Females
Status: UNKNOWN
Conditions: Urinary Tract Infection
Interventions: DRUG: Levofloxacin|DRUG: Solifenacin succinate|DRUG: Placebo (for Solifenacin succinate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Cooling Sensation and Consumer Liking of a Skin Disinfectant Spray
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Prototype disinfectant spray formulation|OTHER: Reference product|OTHER: Negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery
Status: RECRUITING
Conditions: Patient|Satisfaction
Interventions: DRUG: Dexmedetomidine|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Computerized, Adaptive Therapeutic Gaming Approach Training Visual Perceptual Skills in Children With CVI
Status: ACTIVE_NOT_RECRUITING
Conditions: Cerebral Visual Impairment
Interventions: OTHER: Adaptive Therapeutic gaming|OTHER: Non-adaptive Therapeutic gaming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maxillary Nerve Blocks in Children - An MRI Study of the Suprazygomatic Approach
Status: RECRUITING
Conditions: Nerve Block|Cleft Palate|Analgesia
Interventions: OTHER: Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)
Status: TERMINATED
Conditions: Critical Illness|Enteral Nutrition|Enteral Feeding Intolerance
Interventions: DRUG: TAK-954|DRUG: Metoclopramide|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pomegranate Improve Biological Recovery Kinetics in Elite Weightlifter
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Natural Pomegranate Juice|DIETARY_SUPPLEMENT: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging
Status: NOT_YET_RECRUITING
Conditions: Myocardial Suppression
Interventions: OTHER: Fast + High-fat low-carbohydrate diet|COMBINATION_PRODUCT: Fast + Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rituximab in Eosinophilic Granulomatosis With Polyangiitis
Status: COMPLETED
Conditions: Eosinophilic Granulomatosis With Polyangiitis (EGPA)
Interventions: DRUG: Rituximab|DRUG: Placebo-rituximab|DRUG: Cyclophosphamide|DRUG: Placebo-cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Regimen of Bendamustine-Debulking Followed by ABT-199 and GA101-Induction and -Maintenance in CLL (CLL2-BAG)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leucemia
Interventions: DRUG: Bendamustine|DRUG: GA101|DRUG: ABT-199
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating Patients With Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: BIOLOGICAL: DC-CIK|DRUG: IL-2/IFN-α
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Temozolomide in Unfit NENs Patients Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe Study
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Frailty|Chemotherapy Effect
Interventions: DRUG: Temozolomide capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures
Status: TERMINATED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Status: COMPLETED
Conditions: Hyperphosphatemia|End Stage Renal Disease|ESRD
Interventions: DRUG: Ferric citrate tablet|DRUG: Sevelamer carbonate tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
Status: NOT_YET_RECRUITING
Conditions: Cardiopulmonary Arrest|Pediatric ALL|Resuscitation
Interventions: DEVICE: InterFACE (mHealth tool)|OTHER: Conventional methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Telemonitoring on the Outcome of Heart Failure Patients After an Incidence of Acute Decompensation
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: DEVICE: Medly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intubation on a Paediatric Manikin by Emergency Staff: a Comparison of Airtraq and Glidescope
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: Airtraq|DEVICE: Glidescope|DEVICE: direct laryngoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Does The Type of Exercise Influence Outcome in Rotator Cuff Related Shoulder Pain
Status: COMPLETED
Conditions: Shoulder Pain|Rotator Cuff Injury|Rotator Cuff Tendinitis|Rotator Cuff Impingement Syndrome
Interventions: OTHER: Strengthening exercises program|OTHER: Motor control exercises program|OTHER: Education and advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation Therapy in Neuropathic Painful Spinal Cord Injury Patients
Status: RECRUITING
Conditions: Spinal Cord Injuries|Neuropathic Pain|Neurological Diseases or Conditions
Interventions: DEVICE: High-frequency real-time rTMS protocol|DEVICE: Sham rTMS Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flushing of Internalized Percutaneous Transhepatic Biliary Drainage Catheters
Status: RECRUITING
Conditions: Bile Duct Obstruction
Interventions: PROCEDURE: Flushing of PTBD catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients
Status: COMPLETED
Conditions: Kidney Failure, Chronic
Interventions: DRUG: Glucose-infusion|DRUG: Glucose-insulin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Whether Deferiprone Affects QT Interval in Healthy Subjects
Status: COMPLETED
Conditions: Prolonged QTc Interval
Interventions: DRUG: Deferiprone|DRUG: deferiprone matching placebo tablets|DRUG: moxifloxacin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Once-Daily Investigational Nasal Spray In Adults And Adolescents With Vasomotor Rhinitis
Status: COMPLETED
Conditions: Vasomotor Rhinitis|Rhinitis, Vasomotor
Interventions: DRUG: GW685698X
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of SIBP's MMR Vaccine Versus GSK MMR Vaccine in Children Aged 9-11 Months
Status: NOT_YET_RECRUITING
Conditions: Measles-Mumps-Rubella
Interventions: BIOLOGICAL: SIBP MMR Vaccine|BIOLOGICAL: GSK MMR Vaccine (PRIORIX)|BIOLOGICAL: Yellow Fever Vaccine (Stamaril)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Investigational Drug Versus an Approved Drug in Patients With Osteoarthritis (0663-061)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib|DRUG: Comparator: Diclofenac sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Cardiometabolic Health, Cognition and Academic Performance in Children (HAPHC)
Status: RECRUITING
Conditions: Physical Activity|Cardiometabolic Health
Interventions: BEHAVIORAL: 45-minute daily physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Mulligans Mobilization With Movement in Osteoarthritis Knee.
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: BEHAVIORAL: Mulligan's mobilization with movement MWM added isometric strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or Terlipressin
Status: UNKNOWN
Conditions: Septic Shock|Refractory Shock
Interventions: DRUG: Methylene Blue|DRUG: Terlipressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
Status: NOT_YET_RECRUITING
Conditions: Surgical Wound|Wound Healing Delayed|Heart; Surgery, Heart, Functional Disturbance as Result
Interventions: DEVICE: Isla wound prioritisation module|OTHER: Standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety and Efficacy of Ferrlecit® Maintenance Dosing in Pediatric Hemodialysis Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Sodium Ferric Gluconate Complex in Sucrose.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT