pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Erlotinib (Tarceva) During First Line Standard Platinum Containing Chemo for Advanced Squamous Cell Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer|Carcinoma, Squamous Cell
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
Status: COMPLETED
Conditions: Pregnancy|Polycystic Ovary Syndrome
Interventions: DRUG: metformin plus placebo|DRUG: Metformin plus folic acid|DRUG: placebo plus folic acid|DRUG: placebo alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Effect on Central Macular Thickness of Treatment With MG-O-1002 Eye Drops in Participants Aged Over 45 With Neovascular Age-related Macular Degeneration (nAMD)
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: MG-O-1002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Cellular and Humoral Immunity to COVID-19 in Moscow Residents
Status: COMPLETED
Conditions: Covid19|Respiratory Viral Infection
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 specific IgM and IgG detection|DIAGNOSTIC_TEST: ELISpot: detection of the T cells specific to different SARS-CoV-2 proteins|DIAGNOSTIC_TEST: Flow cytometry: detection of the SARS-CoV-2 specific T-helpers and cytotoxic T lymphocytes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transthoracic vs Transbronchial Cryoablation for Early-stage Peripheral Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer
Interventions: DEVICE: Transthoracic cryoablation|DEVICE: Transbronchial cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation to Test the Efficacy of the High Flow (HF) Continuous Positive Airway Pressure (CPAP) in Patients With Obstructive Sleep Apnea (OSA)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Abnoba Viscum F 20mg in Malignant Pleural Effusion Patients
Status: COMPLETED
Conditions: Malignant Pleural Effusion
Interventions: DRUG: Abnoba Viscum F 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractionated Microneedle Radiofrequency for Treatment of Primary Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Primary Axillary Hyperhidrosis
Interventions: DEVICE: Fractional microneedle RF(United, Peninsula Medical, China)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Doravirine (MK-1439) Experimental Nano Formulations in Healthy Adults (MK-1439-046)
Status: COMPLETED
Conditions: Human Immunodeficiency Virus-1 (HIV-1)
Interventions: DRUG: Treatment A: Doravirine 100 mg film coated tablet|DRUG: Treatment B: Doravirine 150 mg tablet (40% drug loaded granule)|DRUG: Treatment C: Doravirine 150 mg tablet (30% drug loaded granule)|DRUG: Treatment D: Doravirine 150 mg tablet (50% drug loaded granule)|DRUG: Treatment E: Doravirine 100 mg tablet (30% drug loaded granule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transplant Wellness Clinic for Elderly or High Risk Patients Undergoing BMT
Status: RECRUITING
Conditions: Stem Cell Transplant Complications|Myeloma|Lymphoma|Allogeneic and Autologous Stem Cell Transplant
Interventions: OTHER: physical therapy consult|OTHER: Cognitive Assessment|OTHER: Cancer Aging Research Group (CARG) assessment|OTHER: Medication Review|OTHER: Nutrition assessment|OTHER: Laboratory studies|OTHER: Patient satisfaction questionnaire|OTHER: Physician Questionnaire|OTHER: Patient follow-up questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The UCAP 2 Pilot Study
Status: WITHDRAWN
Conditions: COPD|Asthma
Interventions: OTHER: Assessment and Treatment provided to participant by a respirologist using evidence-based guidelines for asthma or COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract Surgery
Status: UNKNOWN
Conditions: Endophthalmitis|Cataracts Infantile|Suture, Complication
Interventions: DEVICE: Vicryl suture|DEVICE: Nylon suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opioid-Sparing Multimodal Analgesia Versus Opioid Analgesia for Postoperative Pain After Elective Craniotomy
Status: COMPLETED
Conditions: Analgesia Post Craniotomy
Interventions: DRUG: Morphine versus multimodal analgesia for post elective craniotomy pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Exam the Efficacy of Oral Health and Mediterranean Diet Interventions in Preventing Cognitive Decline Among Older Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment (MCI)|Oral Health|Mediterranean Diet
Interventions: BEHAVIORAL: oral health + MED diet|BEHAVIORAL: oral health|BEHAVIORAL: MED diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: L- Shape Symphyseal Autogenous Bone Block for Alveolar Ridge Augmentation in Anterior Maxilla and Mandible
Status: COMPLETED
Conditions: Atrophic Anterior Alveolar Ridge
Interventions: PROCEDURE: harvesting bone block|PROCEDURE: Recipient site preparation|PROCEDURE: implant insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pyridoxamine Supplementation on Microvascular Function in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Microvascular Function|Retinopathy, Diabetic|Nephropathy, Diabetic|Neuropathy, Diabetic
Interventions: DIETARY_SUPPLEMENT: Pyridoxamine 300mg per day|OTHER: Placebo 300mg placebo per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: DRUG: CC-90010|DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of Thromboembolism Disease: A Cohort Study
Status: COMPLETED
Conditions: Vascular Diseases|Embolism and Thrombosis|Phlebitis|Venous Insufficiency|Pulmonary Embolism
Interventions: OTHER: procedure of Deep Vein Thrombosis (DVT) and PE (Pulmonary Embolism) diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acute Heart Graft Rejection Screening by Cardiac Magnetic Resonance Imaging
Status: WITHDRAWN
Conditions: Cardiac Graft
Interventions: PROCEDURE: cardiac MRI|DRUG: gadobenic acid intravenous injection 0.2 ml/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Stable Angina, NSTEMI and STEMI Undergoing PCI
Status: UNKNOWN
Conditions: Cardiovascular Disease|Stable Angina|Myocardial Infarction|Coronary Artery Disease
Interventions: DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Polycystic Ovarian Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Balancing Effortful and Errorless Learning in Naming Treatment for Aphasia
Status: RECRUITING
Conditions: Aphasia|Stroke
Interventions: BEHAVIORAL: Accuracy-maximized condition|BEHAVIORAL: Effort-maximized condition|BEHAVIORAL: Effort-accuracy balanced condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LAM07: Study to Analyze the Efficacy of a Risk Adapted Treatment Strategy, Including Gemtuzumab Ozogamicin (GO) During Consolidation, for Patients With Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Acute Myeloblastic Leukemia
Interventions: DRUG: gemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-771 in Japanese People With Primary Immunodeficiency Diseases (PID)
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: DRUG: TAK-771
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy, Tolerability and Safety of actiTENS to Those of Level 2 Analgesic Treatments.
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DEVICE: ActiTENS|DRUG: Level 2 Analgesic Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Topical and Intravenous Tranexamic Acid in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Blood Loss
Interventions: DRUG: 0.9% sodium chloride|DRUG: tranexamic acid|DRUG: tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SBRT Combination With rhGM-CSF and Tα1 for Stage IV NSCLC Patients Who Failed in Second-line Chemotherapy
Status: UNKNOWN
Conditions: Lung Cancer Metastatic
Interventions: RADIATION: SBRT|DRUG: Immunological Agent|DRUG: Immunological Factors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide With or Without Oblimersen in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: oblimersen sodium|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Intervention for Older HIV+ Adults With HAND
Status: COMPLETED
Conditions: HIV/AIDS|Aging|Mild Cognitive Impairment|Group, Peer
Interventions: BEHAVIORAL: CRGT|BEHAVIORAL: HIV group therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Standard SOX/XELOX adjuvant chemotherapy plus multimodal rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Subjects With Active Axial Spondyloarthritis Including Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Axial Spondyloarthritis|Ankylosing Spondylitis|r-axSpa|Nr-axSpa
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Study in Healthy Japanese Males Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083
Status: COMPLETED
Conditions: Growth Hormone Disorder|Healthy
Interventions: DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: NNC126-0083|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: placebo|DRUG: NNC126-0083|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CRUSHed vs. Uncrushed Prasugrel in STEMI Patients Undergoing PCI
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DRUG: Prasugrel (Crushed tablets)|DRUG: Prasugrel (Integral tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vaginal Mesh for Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Uterine Prolapse|Vaginal Prolapse|Cystocele|Rectocele
Interventions: DEVICE: synthetic monofilament polypropylene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Field Versus Pulsed High Intensity Laser in the of Osteoprosis
Status: COMPLETED
Conditions: Osteopenia or Osteoporosis
Interventions: OTHER: Pulsed Electromagnetic Field|OTHER: Exercise Program|OTHER: Pulsed High Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ebastine/Pseudoephedrine on Subacute Cough
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: Rhinoebastel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability DS-1971a Suspension and Tablets and Food Effect on DS-1971a Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DS-1971a suspension|DRUG: DS-1971a tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Management of Palmar Hyperhidrosis With Hydrogel-based Iontophoresis
Status: COMPLETED
Conditions: Hyperhidrosis|Hyperhidrosis Palmaris et Plantaris
Interventions: DEVICE: Hydrogel electrode-based iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Surgical sTaging vs Endoscopic Ultrasound in Lung Cancer: a Randomized Clinical Trial (ASTER Study)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: PROCEDURE: Endoscopic ultrasound staging|PROCEDURE: Surgical staging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized Open Label Study of KLH-2109 in Patients With Endometriosis(1)
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: KLH-2109|DRUG: KLH-2109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Lorcaserin Hydrochloride on Energy Metabolism and Food Intake
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Placebo|DRUG: Lorcaserin 10mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study to Determine Skin Irritation and/or Sensitization Potential of an Antifungal Cream Containing Trolamine (Repeated Insult Patch Test)
Status: COMPLETED
Conditions: Hypersensitivity
Interventions: DRUG: Butenafine HCl 1% (BAY1896425)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Importance of Hollow or Solid Centralizer for Polished, Collarless and Tapered Stems in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Hollow Centralizer|PROCEDURE: Solid Centralizer|DEVICE: MS-30 femoral stem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and PK/PD of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN) (NewPLACE)
Status: COMPLETED
Conditions: Glomerulonephritis|Membranous Nephropathy|antiPLA2R Positive
Interventions: DRUG: MOR202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Education and Exercise for Patients With Longstanding Hip and Groin Pain
Status: RECRUITING
Conditions: Hip Pain Chronic|Femoro Acetabular Impingement|Groin Injury
Interventions: OTHER: Usual care|OTHER: HIPSTER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Group-based Psychotherapy to Address Emotional Stress in at Risk ICU Survivors
Status: WITHDRAWN
Conditions: Post Intensive Care Syndrome|Anxiety|Traumatic Stress|Depression
Interventions: BEHAVIORAL: Managing Stress & Emotions Group (MSEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer|Residual Cancer|Circulating Tumor DNA
Interventions: DRUG: Atezolizumab|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Miswak Versus Standard Measures to Prevent the Incidence of Caries Young Egyptian Adults: A Randomized Controlled Clinical Trial
Status: UNKNOWN
Conditions: Dental Caries
Interventions: OTHER: miswak stick|OTHER: Miswak plus tooth brushing and tooth paste|OTHER: Standard preventive measures (tooth brushing , interdental cleaning and mouth rinse use containing CHX and Fluoride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Per-oral Pyloromyotomy for Treating Infantile Hypertrophic Pyloric Stenosis
Status: UNKNOWN
Conditions: Infantile Hypertrophic Pyloric Stenosis|Pyloromyotomy
Interventions: PROCEDURE: G-POEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of Anthocyanins
Status: COMPLETED
Conditions: Gout
Interventions: DIETARY_SUPPLEMENT: Tart cherry extract 60 mL|DIETARY_SUPPLEMENT: Tart cherry extract 120 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ELAPR002f Injectable Gel in the Treatment of Atrophic Acne Scars
Status: RECRUITING
Conditions: Atrophic Acne Scars
Interventions: DEVICE: ELAPR002f Injectable Gel|OTHER: Saline Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of NWT-03 on Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure|Albuminuria
Interventions: DIETARY_SUPPLEMENT: NWT-03, an egg-white protein hydrolysate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Group Education Trial to Improve Transition in Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 1|Type1diabetes|Insulin Dependent Diabetes
Interventions: OTHER: Active arm|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Red and Infrared Lasers in Treatment of Temporomandibular Disorders
Status: COMPLETED
Conditions: Temporomandibular Disorders
Interventions: RADIATION: Red laser|RADIATION: Infrared laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Post-covid Infection Status and Perioperative Morbidity: A Ambispective Cohort Study
Status: COMPLETED
Conditions: COVID-19|Complication of Anesthesia|Complication of Surgical Procedure|Complication,Postoperative|Sars-CoV-2 Infection
Interventions: PROCEDURE: Receiving inpatient surgical intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pediatric Caudal Anesthesia Block. And Pain Control
Status: COMPLETED
Conditions: Pain, Postoperative|Adverse Reaction to Epidural Anesthesia|Anesthesia, Caudal
Interventions: COMBINATION_PRODUCT: Group A Caudal Epidural Anesthesia with bupivacaine 0.25% and group B with opioid intervenors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Registry to Collect Patient Outcome Date for the BIOMET® Stimulator Systems
Status: TERMINATED
Conditions: Fusion of Spine (Disease)|Fractures, Ununited
Interventions: DEVICE: Biomet® EBI Bone Healing System|DEVICE: Biomet Orthopak® Non-Invasive Bone Growth Stimulator System|DEVICE: Biomet SpinalPak® Non-Invasive Spine Fusion Stimulator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy of Bevacizumab Combined With m-FOLFOXIRI in Borderline Resectable Colorectal Liver Metastases
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab|DRUG: Oxaliplatin|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5-FU
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Long-course Chemoradiotherapy Followed by Immunotherapy for Locally Advanced Mid-low Rectal Cancer
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: RADIATION: radiation|DRUG: PD-1 Monoclonal Antibody|PROCEDURE: TME surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromodulation in Laryngeal Dystonia
Status: RECRUITING
Conditions: Laryngeal Dystonia|Focal Dystonia
Interventions: DEVICE: repetitive transcranial magnetic stimulation (rTMS)|DEVICE: sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-center, Prospective,Randomized Study of Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Dual Anti-platelet Therapy After Coronary Artery Bypass Grafting
Status: COMPLETED
Conditions: Antiplatelet Therapy of Coronary Artery Bypass
Interventions: DRUG: ticagrelor|DRUG: clopidogrel|DRUG: asprin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Behavioral Weight Loss Treatment vs. Weight Watchers
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Weight Watchers|BEHAVIORAL: brief behavioral weight loss treatment|BEHAVIORAL: brief behavioral + Weight Watchers combined treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting
Status: COMPLETED
Conditions: Socket Sealing|Free Gingival Graft|Collagen Membrane
Interventions: PROCEDURE: Socket preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Self-rehabilitation and Tele-rehabilitation Program on the Post-stroke Care Pathway
Status: RECRUITING
Conditions: Hemorrhagic Unilateral Cortico-subcortical Hemispheric Stroke|Ischemic Stroke
Interventions: DEVICE: AutonHome® device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sterile Water Injections for Relieving Ureterolithiasis Pain
Status: WITHDRAWN
Conditions: Ureterolithiasis|Pain
Interventions: OTHER: Diclofenac and sterile water injections|OTHER: Diclofenac and isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: eHealth Intervention to Promote Self-regulation of Physical Activity and Fruit and Vegetable Intake Among Adults Who Visit General Practice
Status: COMPLETED
Conditions: Physical Activity|Fruit and Vegetable Intake|Self-regulation|Empowerment
Interventions: BEHAVIORAL: My Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of the Magnetically Guided Capsule Endoscopy Versus High Definition Gastroscopy
Status: COMPLETED
Conditions: Gastric Focal Lesion
Interventions: DEVICE: Magnetically Guided Capsule (MGCE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD)
Status: RECRUITING
Conditions: Depression|Sequestra
Interventions: DRUG: Fluoxetine|DRUG: Sertraline|DRUG: Vortioxetine|DRUG: Duloxetine|DRUG: Aripiprazole|DRUG: Lithium Carbonate|DRUG: Olanzapine|BEHAVIORAL: GCBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Long-term Respiratory Complications of Severe SARS-CoV-2 Pneumonia - COVID-19
Status: UNKNOWN
Conditions: Severe SARS-CoV2 Pneumonia
Interventions: OTHER: Blood sample and data record
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ultrasound to Enhance Paclitaxel Uptake in Critical Limb Ischemia: the PACUS Trial
Status: COMPLETED
Conditions: Peripheral Arterial Disease, Angioplasty
Interventions: DEVICE: Local exposition of target lesion to high intensity, low-frequency ultrasound|DEVICE: drug eluting ballon angioplasty|DEVICE: Flow occlusion with an angioplasty balloon|DRUG: Local Paclitaxel infusion|PROCEDURE: Angiographic control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Safety/Efficacy of Combination Checkpoint Blockade + External Beam Radiotherapy in Stage IV Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Analysis of Procedural Aspects of Transcatheter Aortic Valve Implantation (TAVI) on Peri-procedural Stroke
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: Balloon Aortic Valvuloplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Natural Fruit Extract Versus the Assumed Key Active Compound in Reducing the Post-prandial Blood Glucose Level
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Natural fruit extract|OTHER: Assumed active|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment of Anal High-grade Squamous Intraepithelial Lesions (HSIL) Through Use of a Chinese Herbal Topical Cream
Status: COMPLETED
Conditions: Anus Neoplasms
Interventions: DRUG: AIJP (Arnebia Indigo Jade Pearl)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Treatment Extension Study With SAR245408 or SAR245409 as a Monotherapy or as a Combination Regimen
Status: COMPLETED
Conditions: Neoplasm Malignant
Interventions: DRUG: SAR245408|DRUG: SAR245409
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Study to Evaluate the Safety and Efficacy of JHM03 in Adult Patients with Upper Limb Spasticity
Status: NOT_YET_RECRUITING
Conditions: Upper Limb Spasticity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Additional Effect of Different Taping Applications in Patients With Lumbar Radiculopathy
Status: COMPLETED
Conditions: Low Back Pain, Recurrent|Kinesiotape|Quality of Life|Physiotherapy
Interventions: OTHER: kinesio taping|OTHER: rigid taping|OTHER: placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic Transplantation Using Total Lymphoid Irradiation (TLI) and Anti-Thymocyte Globulin (ATG) for Older Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Blood Cancer|Leukemia
Interventions: DRUG: Cyclosporine|DRUG: Anti-thymocyte globulin (ATG)|DRUG: Mycophenolate mofetil (MMF)|DRUG: Filgrastim|RADIATION: Total Lymphoid Irradiation (TLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-Invasive Neuromodulation Device for Treatment of Migraine Headache
Status: COMPLETED
Conditions: Migraine Headache, Episodic
Interventions: DEVICE: neuromodulation for episodic migraine headache
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetylpyridium Chloride (CPC) Based Chewing Gum and Gingivitis
Status: COMPLETED
Conditions: Gingivitis|Plaque, Dental|Periodontal Diseases
Interventions: DRUG: Cetylpyridinium Chloride (CPC) 0.09% + Xylitol chewing gum|DRUG: Xylitol only chewing gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dose-Escalation Study of Ponatinib, a FLT3 Inhibitor, With and Without Combination of 5-Azacytidine, in Patients With FLT3-Mutated Acute Myeloid Leukemia (AML)
Status: WITHDRAWN
Conditions: Leukemia|FLT3-Mutated Acute Myeloid Leukemia|FLT3-Mutated High-Risk Myelodysplastic Syndrome
Interventions: DRUG: Ponatinib|DRUG: 5-azacytidine|BEHAVIORAL: Phone Calls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PeerScope B System™ Clinical Protocol
Status: COMPLETED
Conditions: Colon Cancer|Colon Diseases|Colon Polyps|Colon Adenomas
Interventions: DEVICE: colonoscopy system (PeerScope B System™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Outpatient Clinical Trial Using Ivermectin and Doxycycline in COVID-19 Positive Patients at High Risk to Prevent COVID-19 Related Hospitalization
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Ivermectin Tablets|DRUG: Doxycycline Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|DRUG: Oleclumab|DRUG: Monalizumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Ability Of A Crossover Study Design To Detect The Efficacy Of Pregabalin In Post-Traumatic Neuropathic Pain Patients
Status: COMPLETED
Conditions: Nerve Pain
Interventions: DRUG: Pregabalin (Lyrica)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Interleukin-11 Can Prevent and Treat of Radioactive Oral Mucitis
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Recombinant Human Interleukin-11|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTENSIVE TREATMENT WITH ROBOTIC PLUS VIBRATION IN STROKE
Status: UNKNOWN
Conditions: Stroke|Activities, Motor|Quality of Life|Sensitivity|Upper Extremity Paresis
Interventions: DEVICE: Robotic|DEVICE: Vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CS-7017 in Colorectal Cancer Patients Who Have Achieved Disease Control Following First-Line Chemotherapy
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: CS-7017|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Postprandial Responses to Two Cereal Foods Differing by Their SDS Content and GI Consumed Alone.
Status: COMPLETED
Conditions: Metabolism and Nutrition Disorders
Interventions: OTHER: High-SDS biscuit|OTHER: Low-SDS extruded cereals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Neurodynamic Mobilization Exercise on Lower Limb Pain in Patients With Rheumatoid Arthritis.
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Neurodynamic mobilization exercise|OTHER: Conservative Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Bleeding Following Hypertonic Saline Sclerotherapy Compared to Brand Ligation for Symptomatic Hemorrhoids
Status: WITHDRAWN
Conditions: Hemorrhoids|Bleeding|Pain
Interventions: PROCEDURE: Rubber Band Ligation|PROCEDURE: Hypertonic Saline Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Analgesia vs Adductor Canal Block in Bilateral TKA
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: Continuous epidural block|PROCEDURE: Bilateral single-shot bilateral adductor canal blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of the Effects of QS-M Needle Free Injector and Glargine Pen Subcutaneous Injection of Insulin Glargine on Insulin Use
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DEVICE: QS-M Needle Free Injector|DEVICE: Glargine pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The PK and PD of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin 5mg|DRUG: Dapagliflozin 10mg|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endoscopic Visualisation of Anastomosis in Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Rectal Cancer|Colorectal Cancer|Anastomotic Leak|Intraoperative Endoscopy
Interventions: DIAGNOSTIC_TEST: Intra-operative endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety Following a Single Dose of Influenza Vaccines in Healthy Children Who Received Either One or the Other Vaccine (an Adjuvanted Sub-unit Influenza Vaccine and a Non-adjuvanted Split Virion Influenza Vaccine) in the Previous V70P2 Study
Status: COMPLETED
Conditions: FLU
Interventions: BIOLOGICAL: Influenza Trivalent Inactivated Vaccines|BIOLOGICAL: Influenza Trivalent Inactivated Vaccines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Intralipid Efficacy in Women With Unexplained Recurrent Implantation Failure
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Intralipid 20%|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) + Xeloda (Capecitabine)as Maintenance Therapy in Patients With HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Explore the Effectiveness and Feasibility of HERADERM Hydrogel Wound Dressing on Caesarean Section Surgical Site
Status: RECRUITING
Conditions: Cesarean Section|Surgical Wound|Surgical Wound Infection|Wounds and Injuries
Interventions: DEVICE: HERADERM Hydrogel Wound Dressing (Sterile)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metformin Pharmacokinetics in Patients With Chronic and Acute Heart Failure
Status: UNKNOWN
Conditions: Heart Failure, Systolic
Interventions: OTHER: Blood draws and urine samples for metformin concentration measurements|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis?
Status: COMPLETED
Conditions: Severe Sepsis|Septic Shock|Acute Kidney Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Validity of Kleinhauer Betke in Women With Known Hemoglobinopathy for Fetal-maternal Hemorrhage
Status: COMPLETED
Conditions: Fetal-Maternal Hemorrhage
Interventions: DIAGNOSTIC_TEST: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A PhaseⅡ Study: SOX vs SP in Adjuvant Chemotherapy After D2 Surgery
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: S-1|DRUG: oxaliplatin|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nexium Study To Suppress Nausea During Chemotherapy
Status: TERMINATED
Conditions: Nausea
Interventions: DRUG: esomeprazole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triple-branch Stent Graft Placement for the Treatment of Acute DeBakey I Aortic Dissection
Status: COMPLETED
Conditions: Acute Aortic Dissection
Interventions: PROCEDURE: triple-branched stent graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Indirect and Direct MR Arthrography of the Shoulder Using Arthroscopic Correlation
Status: WITHDRAWN
Conditions: Shoulder Pain
Interventions: PROCEDURE: Indirect MRA of shoulder|DRUG: Gadopentetate Dimeglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Assess the Pharmacokinetics, Efficacy, and Safety of Atezolizumab Administered Intravenously (IV) as a Single Agent or in Combination With Chemotherapy in Chinese Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Atezolizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect and Tolerance of Preservative Free NAAGA on the Inflammatory Component and Symptoms of Dry Eye Syndrome in Allergic Conjunctivitis Patients
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: NAABAK eyedrops|DRUG: Saline eyedrops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke
Status: RECRUITING
Conditions: Ischemic Stroke, Acute
Interventions: DRUG: Minocycline hydrochloride capsule|DRUG: Placebo capsules of Minocycline hydrochloride capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: gastric emptying test|OTHER: gut hormones determination|OTHER: Continuous Glucose Monitoring|DRUG: Insulin single bolus|DRUG: Insulin double-wave bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease
Status: COMPLETED
Conditions: Coronary Heart Disease
Interventions: DRUG: MPSK3169A|DRUG: MPSK3169A|DRUG: MPSK3169A|DRUG: MPSK3169A|DRUG: MPSK3169A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-label Phase I Study for PEP or Treatment of HS-ARS PLX-R18 for the Post-Exposure Prevention (PEP) or Treatment of Hematopoietic Syndrome of Acute Radiation Syndrome (HS-ARS)
Status: UNKNOWN
Conditions: Ionizing Radiation Exposure
Interventions: BIOLOGICAL: Cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Influencing the Mortality of Patients With Subarachnoid Haemorrhage
Status: COMPLETED
Conditions: Spontaneous Subarachnoid Hemorrhage
Interventions: OTHER: Spontaneous subarachnoid haemorrhage survival cohort|OTHER: Spontaneous subarachnoid haemorrhage mortality cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Eliminating Gastric Residual Volume Monitoring on Ventilator Associated Events
Status: NOT_YET_RECRUITING
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: eliminating gastric residual volume monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Assess the Efficacy and to Evaluate Safety of HT047 in Patients With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: HT047 High-dose group|DRUG: HT047 Low-dose group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficiency and Safety of Paxlovid for COVID-19 Patients With Severe Chronic Kidney Disease
Status: RECRUITING
Conditions: COVID-19|Renal Insufficiency, Chronic
Interventions: DRUG: Nirmatrelvir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Resync|DIETARY_SUPPLEMENT: Resync + Collagen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE