pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Test the Effect of 2 Different Doses of Topical GW870086X on Atopic Dermatitis Also Including a Postive Control and a Placebo
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: GW870086 2.0%|DRUG: GW870086 0.2%|DRUG: FP 0.05%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Thermal Stress on Pulmonary Absorption and Toxicokinetics of 3 Organic Solvents
Status: UNKNOWN
Conditions: Heat
Interventions: OTHER: Heat stress (21)|OTHER: Heat stress (25)|OTHER: Heat stress (30)|OTHER: Heat Stress (21) +TOL|OTHER: Heat stress (25) + TOL|OTHER: Heat stress (21) + TOL|OTHER: Heat stress (21) + ACE|OTHER: Heat stress (25) + ACE|OTHER: Heat stress (30) + ACE|OTHER: Heat stress (21) + DCM|OTHER: Heat stress (25) + DCM|OTHER: Heat stress (30) + DCM|OTHER: Heat stress (21) + TOL (dermal)|OTHER: Heat stress (25) + TOL (dermal)|OTHER: Heat stress (30) + TOL (dermal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Thoracic Paravertebral Block on Heart Rate Variability (HRV)
Status: UNKNOWN
Conditions: Breast Surgery|Thoracic Paravertebral Block|HRV|Autonomic Nervous System
Interventions: OTHER: Left thoracic paravertebral block|OTHER: Right thoracic paravertebral block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MGC Health COVID-19 & Flu A+B Home Multi Test Usability Study
Status: COMPLETED
Conditions: COVID-19|Influenza A|Influenza B
Interventions: DIAGNOSTIC_TEST: MGC Health COVID-19 & Flu A+B Home Multi Test|DIAGNOSTIC_TEST: MGC Health COVID-19 & Flu A+B Home Multi Test (2 to 13 y/o)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MSCs for Prevention of MI-induced HF
Status: RECRUITING
Conditions: Myocardial Infarction, Acute|Myocardial Infarction First|Myocardial Infarction, Anterior Wall|Cardiac Remodeling, Ventricular|STEMI|Regenerative Medicine|Heart Failure
Interventions: BIOLOGICAL: Umbilical Cord-Derived Wharton's Jelly Mesenchymal Stem Cells (WJ-MSCs)|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Ascorbic Acid Treatment of CMT1A
Status: COMPLETED
Conditions: Charcot-Marie-Tooth Disease, Type Ia
Interventions: DRUG: Ascorbic acid (Vitamin C)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Spasticity
Interventions: DEVICE: Dry needling|DEVICE: Sham dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Immunopheresis® Alone or In Combination With Chemotherapy Versus Chemotherapy Alone in Treatment of Advanced Breast Cancer Patients
Status: UNKNOWN
Conditions: Advanced Breast Cancer
Interventions: OTHER: Plasma soluble TNF receptor pulldown|OTHER: Plasma soluble TNF receptor pulldown + chemotherapy|DRUG: Chemotherapy Drugs, Cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Trivalent Split Influenza Vaccine Using the Strain Composition 2008/2009
Status: COMPLETED
Conditions: Seasonal Influenza, Vaccine
Interventions: BIOLOGICAL: Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endotypic Traits and Obstructive Sleep Apnea Surgery
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Acetazolamide 500 MG QHS|DRUG: Eszopiclone 3 mg QHS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes
Status: COMPLETED
Conditions: Asthma|Children
Interventions: DRUG: Albuterol - Experimental|DRUG: Albuterol - Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Symptom Management Application for Children at the Early Stage of Cancer Survivorship and Their Caregivers
Status: NOT_YET_RECRUITING
Conditions: Oncology|Survivorship
Interventions: OTHER: Symptom management mobile health application with personalised support|OTHER: Wait-list Symptom management mobile health application with personalised support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of PK of AC-1204 Mixed in Water, AC-1202 Mixed in Water, and AC-1202 Mixed in Ensure® on Ketone Body Production
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AC-1204 mixed in water|DRUG: AC-1202 mixed in water|DRUG: AC-1202 mixed in Ensure®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Tislelizumab Combined With Chemotherapy or Radiotherapy in the Treatment of Advanced or Recurrent Metastatic Elderly Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Tislelizumab|RADIATION: Radiation|DRUG: Paclitaxel|DRUG: Platinum: cisplatin, carboplatin, naidaplatin and other platinum drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Gabapentin Versus Placebo for Treatment of Postoperative Pain Following Photorefractive Keratectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Gabapentin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: Tiagabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Studies of rHSA/GCSF Fusion Protein For Injection to Treat Neutropenia
Status: COMPLETED
Conditions: Underdose (Unintentional)|Cancer|Tumor
Interventions: DRUG: rHSA/GCSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Kinesio Taping on Lymphedema Following Head and Neck Cancer Therapy
Status: COMPLETED
Conditions: Lymphedema|Head and Neck Cancer|Kinesio Taping|Therapy
Interventions: DEVICE: Kinesio Tex Gold
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Followed by Peripheral Stem Cell Transplantation in Treating Patients With Relapsed or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: yttrium Y 90 monoclonal antibody B3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Healthy Lifestyle Intervention for High-Risk Minority Pregnant Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Emotional Disturbances|Depression|Pregnancy Late|Post-Partum Depression|Anxiety|Nutritional Deficiency
Interventions: BEHAVIORAL: COPE-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Exosomes Derived From Epicardial Fat in Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Epicardial fat biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, and Efficacy of NBI-98854 for the Treatment of Pediatric Subjects With Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome
Interventions: DRUG: Valbenazine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Focal Salvage High-Dose-Rate Brachytherapy for Prostate Gland Only Recurrence
Status: RECRUITING
Conditions: Prostate Cancer|HDR
Interventions: PROCEDURE: High-Dose-Rate Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parallel, Double-dummy, Superiority Study Levocetirizine/Pseudoephedrine x Zina for Allergic Rhinitis in Brazil
Status: NOT_YET_RECRUITING
Conditions: Allergic Rhinitis
Interventions: DRUG: Administration of investigation of Eurofarma drug|DRUG: Administration of Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on the Bioequivalence of Perindopril Tert-butylamine Tablets Taken on After Meals in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Perindopril tert-Butylamine tablets （ Produced by Haisco）|DRUG: Perindopril tert-Butylamine tablets（ACERTIL®）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Disentangling Anxiety Sensitivity and Anxiety-induced Physiological Stress Response
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: HPA, ANS stimulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax 100 mg d1，200 mg d2，400 mg d3-28；
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Pre-operative Radiation Therapy for Soft Tissue Sarcomas of the Extremity and Chest-wall
Status: ACTIVE_NOT_RECRUITING
Conditions: Soft Tissue Sarcoma
Interventions: RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D-Printed Hand Orthosis Versus Thermoplastic Orthosis
Status: NOT_YET_RECRUITING
Conditions: Thumb Osteoarthritis|CMC|Splints
Interventions: DEVICE: splint (orthosis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Vest Treatment (high frequency chest wall oscillation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 6-week Trial of the Efficacy and Safety of Asenapine Compared to Placebo in Participants With an Acute Exacerbation of Schizophrenia (P06124)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Asenapine 5 mg|DRUG: Asenapine 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Safety of Coronavirus Infection (COVID-19) Messenger RNA (mRNA) Vaccine Administration in the Setting of a Previous Adverse Reaction
Status: RECRUITING
Conditions: COVID-19|Corona Virus Infection
Interventions: BIOLOGICAL: Pfizer-BioNTech mRNA COVID-19 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncorine (H101) Combined With Tislelizumab and Chemotherapy in Previously Untreated Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Untreated Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Recombinant human adenovirus type 5 injection (H101) combined with tirilizumab and platinum-containing two-drug chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relevance of a Web-mediated Follow up in Patients Having a Lymphoma With a High Risk of Relapse in Complete or Partial Response
Status: TERMINATED
Conditions: Lymphoma, T-Cell|Lymphoma, Large B-Cell, Diffuse|Lymphoma, Hodgkin
Interventions: DEVICE: MOOVCARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open, Randomized Phase II Trial to Investigate the Efficacy and Safety of the PLK-1 Inhibitor BI 2536 in Patients With Advanced, Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Neoplasms
Interventions: DRUG: BI 2536
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Individualized Neo-antigen mRNA Cancer Vaccine InnoPCV in Advanced Solid Tumor Treatment
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Biological: Tislelizumab|DRUG: Biological: InnoPCV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Compare Ofloxacin With Azitromycin for Pelvic Inflammatory Disease (PID) Treatment
Status: COMPLETED
Conditions: Pelvic Inflammatory Disease
Interventions: DRUG: Ofloxacin group A, Azitromycin group B|DRUG: azitromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine (DAC) w/ or w/o Valproic Acid (VPA) in Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Acute Myelogenous Leukemia
Interventions: DRUG: Decitabine|DRUG: Valproic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.
Status: TERMINATED
Conditions: Depressive Episodes, Bipolar I Depression
Interventions: DRUG: SEP-4199 CR 200 mg|DRUG: SEP-4199 CR 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain
Status: RECRUITING
Conditions: Knee Osteoarthritis|Persistent Postsurgical Pain|Chronic Knee Pain
Interventions: PROCEDURE: Conventional Radiofrequency ablation of the genicular nerves|PROCEDURE: Cooled Radiofrequency ablation of the genicular nerves|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3023703 Testing Pain Relief After Wisdom Teeth Removal
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Placebo|DRUG: LY3023703|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of EPC2407, A Anti-Cancer Drug With Vascular Disrupting Activity: In Patients With Advanced Cancer
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: EPC2407 (crinobulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Inhaled Synthetic THC/CBD for Improving Physical Functioning and for Modulating Cachexia Progression in Patients With Advanced Cancer and Associated Cachexia
Status: SUSPENDED
Conditions: Cannabis Use|Cachexia; Cancer|Advanced Cancer
Interventions: DRUG: PPP011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline for Acute Ischemic Stroke Undergoing Endovascular Treatment Due to Basilar Artery Occlusion (MIST-B)
Status: RECRUITING
Conditions: Ischemic Stroke, Acute|Minocycline|Endovascular Treatment|Basilar Artery Occlusion
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics and Overreaching Recovery
Status: UNKNOWN
Conditions: Fatigue; Muscle, Heart|Immunosuppression
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Re:MIX: a Teen Pregnancy Prevention Program With Young Parents as Peer Educators, EngenderHealth
Status: COMPLETED
Conditions: Sexual Behavior|Unprotected Sex
Interventions: BEHAVIORAL: Re:MIX, a multi-layer comprehensive teen pregnancy prevention intervention aimed at reducing pregnancy and STIs among youth ages 13-17
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PK Study of YH22162 FDC Compared to Combination of Twynsta and Hygroton
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: YH22162|DRUG: Telmisartan/Amlodipine 80/5 mg (FDC)|DRUG: Chlorthalidone 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Exploration of Genotype Based Personalized Prescription of Cyclophosphamide in Systemic Lupus Erythematosus Treatment
Status: COMPLETED
Conditions: Lupus Erythematosus, Systemic|Adverse Effects
Interventions: GENETIC: Polymorphism Analysis|DRUG: Cyclophosphamide|OTHER: Pharmacokinetic analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Provisional Versus Routine Kissing Balloon Technique After Main Vessel Crossover Stenting for Bifurcated Lesions.
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: stent technique: Provisional fKBT|PROCEDURE: stent technique: Routine fKBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Long Term Safety, Tolerability and Efficacy of Aliskiren Compared to Enalapril in Pediatric Hypertensive Patients 6-17 Years of Age
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Aliskiren|DRUG: Enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Pegasys (Peginterferon Alfa-2a) Plus Copegus (Ribavirin) in Participants With Chronic Hepatitis C (CHC), Genotype 2, 3, 1 or 4, Undergoing Opioid Maintenance Therapy
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.
Status: WITHDRAWN
Conditions: Infections, Bacterial
Interventions: DRUG: GSK945237|DRUG: Placebo|DRUG: Linezolid|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: KPL-404|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis
Status: RECRUITING
Conditions: Non Alcoholic Steatohepatitis|Non-Alcoholic Fatty Liver Disease|Fecal Microbiota Transplantation|FMT|Prebiotics|Probiotics|Microbiome|Intestinal Microbiome|Gut Microbiome
Interventions: COMBINATION_PRODUCT: Lyophilized fecal microbiota transplantation capsules|COMBINATION_PRODUCT: Placebo capsules|DIETARY_SUPPLEMENT: A. soehngenii|DIETARY_SUPPLEMENT: Pasteurized A. muciniphila|DIETARY_SUPPLEMENT: B. animalis subsp. lactis|DIETARY_SUPPLEMENT: Fructo-oligosaccharides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms|Solid Tumor, Adult|Non-Hodgkin Lymphoma|Myelodysplastic Syndromes
Interventions: DRUG: JNJ-64619178
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Tenofovir DF|DRUG: lopinavir/ritonavir with 2 Nucleoside RTIs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PK and PD Interaction Between Tegoprazan and NOACs After Multiple Oral Dosing in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tegoprazan 50mg|DRUG: Edoxaban 60mg|DRUG: Apixaban 5mg|DRUG: Rivaroxaban 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluid Coloading and the Incidence of Hypotension
Status: COMPLETED
Conditions: Complications; Cesarean Section|Anesthesia; Adverse Effect, Spinal and Epidural|Other Fluid Overload
Interventions: BIOLOGICAL: Cristalloid and colloid coloading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating of Recombinant Human Factor IX (BeneFIX) and a New Formulation of BeneFIX (rFIX-R) in Moderate to Severe Hemophilia B
Status: COMPLETED
Conditions: Hemophilia B
Interventions: DRUG: rFIX|DRUG: rFIX-R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: dactinomycin|BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: vincristine sulfate|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effectiveness of Muscle Inhibition and Space Correction Techniques of Kinesiotaping Method in Female Patients With Myofascial Pain Syndrome Related to Upper Trapezius Active Trigger Points
Status: COMPLETED
Conditions: Female Patients With Myofascial Pain Syndrome (MPS) Related to Upper Trapezius Active Trigger Points (TP)
Interventions: OTHER: Kinesiotaping with space correction technique|OTHER: Kinesiotaping with muscle inhibition technique|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Periodontal Treatment on Serum Levels of Hepcidin and Hemoglobin
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Periodontal Treatment|DRUG: Albendazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety & Efficacy of Selumetinib When Given in Combination With Standard First Line Treatment for Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic NSCL Cancer Stage IIIB IV
Interventions: DRUG: selumetinib|DRUG: gemcitabine|DRUG: cisplatin|DRUG: carboplatin|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor and ASA vs. ASA Only After Isolated Coronary Artery Bypass Grafting in Patients With Acute Coronary Syndrome
Status: RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor 90mg twice daily and ASA 75-100 mg daily|DRUG: ASA 75-160 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial-intelligence-based QUAntification of Size measuremeNts of Adenoma in Routine Endoscopy
Status: RECRUITING
Conditions: Colorectal Polyp|Colorectal Adenoma
Interventions: DEVICE: POSEIDON size estimation software with the EndoMind polyp detection system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sorafenib Tosylate and Chemoembolization With Doxorubicin Hydrochloride and Mitomycin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: mitomycin C|DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Electro Magnetic Interference of Using Tablet and Smart Phone on Leadless Pacemaker (MICRA)
Status: COMPLETED
Conditions: Bradycardia, Atrial Tachyarrhythmia
Interventions: DEVICE: Use of a Tablet|DEVICE: Use of a Smart Phone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Supplementation of Flaxseed, Hesperidin, Flaxseed and Hesperidin Together in Non-alcoholic Fatty Liver Disease: A Randomized, Controlled Study
Status: UNKNOWN
Conditions: Non Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement: hesperidin and flaxseed|DIETARY_SUPPLEMENT: Dietary Supplement: hesperidin|DIETARY_SUPPLEMENT: Dietary Supplement: flaxseed|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic Atrophy
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: BI 754132
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma or Hormone Receptor Positive Her2 Negative Metastatic Refractory Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Hormone Receptor-Positive Breast Carcinoma|Locally Advanced Cutaneous Melanoma|Metastatic Acral Lentiginous Melanoma|Metastatic Conjunctival Melanoma|Metastatic Cutaneous Melanoma|Metastatic HER2-Negative Breast Carcinoma|Metastatic Mucosal Melanoma|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Recurrent Acral Lentiginous Melanoma|Recurrent Cutaneous Melanoma|Recurrent Mucosal Melanoma|Refractory HER2-Negative Breast Carcinoma|Unresectable Acral Lentiginous Melanoma|Unresectable Cutaneous Melanoma|Unresectable Mucosal Melanoma
Interventions: BIOLOGICAL: Neoantigen Peptide Vaccine|BIOLOGICAL: Nivolumab|DRUG: Poly ICLC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics, and Safety of Single-dose Sotrovimab in High-risk Pediatric Participants With Mild to Moderate COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: Sotrovimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma
Status: SUSPENDED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: Bevacizumab and Carboplatin|DRUG: Bevacizumab and Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Transdermal Optical Imaging (TOI) as a Non-invasive Measure of Hydration Status: Phase 3a for Model Development
Status: COMPLETED
Conditions: Dehydration
Interventions: OTHER: GENPOP Passive dehydration (75% reduction in fluid intake|OTHER: GENPOP Ad lib fluid intake|OTHER: EXERCISE without fluid replacement|OTHER: EXERCISE with fluid replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Trachomatous Trichiasis (TT)|Eye Diseases|Eyelid Diseases|Trachomatous|Trichiasis
Interventions: DRUG: Fluorometholone 0.1% Oph Susp|DRUG: Artificial Tears
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Results Obtained in the Regular Clinical Practice of a Clinical Ultrasound Classroom For Primary Care Physicians As a Formative Intervention System
Status: RECRUITING
Conditions: Family Medicine|Clinical Ultrasound|Primary Care
Interventions: PROCEDURE: A training intervention on clinical ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology
Status: UNKNOWN
Conditions: Severe Sepsis
Interventions: DRUG: Flucis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2a, Ribavirin and Epoetin β in Coinfected Patients HCV/HIV Not Responding to Previous Treatment Regimens
Status: COMPLETED
Conditions: Hepatitis C|HIV Infections
Interventions: DRUG: Peginterferón alfa-2a (40 KD) (Pegasys®) 180 ug/week|DRUG: Ribavirin (Copegus®) 1600 mg/day|DRUG: Epoetin β (450 UI/kg/week)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without G-CSF in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: BIOLOGICAL: Filgrastim|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Mitoxantrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Pulse Width Versus Low Frequency DBS in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis
Status: COMPLETED
Conditions: Recurrent Pericarditis
Interventions: DRUG: Rilonacept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of Viral Infections' Exposition Preceding the Type 1 Diabetes (T1D) Diagnostic in Children of the Isis-Diab Cohort. Search for Explanations of of the Disease's Early Onset
Status: UNKNOWN
Conditions: Diabetes Mellitus|Insulin-Dependent
Interventions: OTHER: Collect of data on viral environment of T1D patients|GENETIC: Collect of blood samples for DNA extraction and genetic characterization (GWAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Amount of Drug That Becomes Available in the Blood Circulation When Savolitinib is Administered Alone and in Combination With Itraconazole
Status: COMPLETED
Conditions: Solid Tumour
Interventions: DRUG: Savolitinib|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AZD4831|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Plasma Sodium Concentration on Blood Pressure Regulators During Hemodialysis
Status: COMPLETED
Conditions: Patients With End Stage Renal Disease on Hemodialysis
Interventions: DEVICE: Hemocontrol hemodialysis|DEVICE: Standard hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Program to Personalize Care & Improve Quality of Life for Women With Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: OTHER: Pre-study Questionnaire|OTHER: Educational Presentations|OTHER: CAM Therapies|OTHER: Post-study Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intravenous Lidocaine to Reduce ED50 for Propofol Administered Using Target Controlled Infusion (TCI) During Gastroscopy
Status: RECRUITING
Conditions: Diagnostic Gastroscopy
Interventions: DRUG: Lidocaine 2% Injectable Solution|DRUG: Saline administration as placebo|DRUG: Propofol injection|PROCEDURE: gastroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Performance and Safety Assessment of the Mechanical Decongestant Seawater Spray Enriched with Essential Oils from Laboratoires Gilbert in Patient with Acute Rhinitis Associated with Nasal Obstruction
Status: NOT_YET_RECRUITING
Conditions: Acute Rhinitis|Nasal Obstruction|Rhinosinusitis|Rhinopharyngitis|Allergic Rhinitis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Abuse Liability of Oxycodone HCl/Niacin in Subjects With a History of Opioid Abuse
Status: COMPLETED
Conditions: Opioid Abuse
Interventions: DRUG: Acurox 5/30mg taken first|DRUG: Oxycodone 5mg taken first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Eradication of Carbapenem Resistant Klebsiella Pneumonia
Status: UNKNOWN
Conditions: Anti-Biotic Resistance|Klebsiella Pneumoniae
Interventions: DIETARY_SUPPLEMENT: VSL#3|DRUG: Polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Mesenchymal Stromal Cell Therapy in Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: BIOLOGICAL: Mesenchymal stromal cell|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Theranova 400 Dialyzer In End Stage Renal Disease (ESRD) Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Theranova 400 dialyzer|DEVICE: Elisio-17H dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative or Postoperative Therapy of Patients With Stages IB, II, IIIA Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas
Status: COMPLETED
Conditions: Adult Liposarcoma|Metastatic Liposarcoma|Metastatic Osteosarcoma|Recurrent Adult Soft Tissue Sarcoma|Recurrent Liposarcoma|Recurrent Osteosarcoma|Stage IV Adult Soft Tissue Sarcoma
Interventions: DRUG: Pazopanib Hydrochloride|DRUG: Oral Topotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
Status: COMPLETED
Conditions: Colorectal Cancer|Colonic Adenoma|Bowel Preparation
Interventions: DEVICE: Pure-Vu System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints
Status: COMPLETED
Conditions: Memory Disorders, Age-Related|Retention Disorders, Cognitive
Interventions: DRUG: EGb 761® (Tanakan®)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency
Status: WITHDRAWN
Conditions: Primary Immune Deficiency Disorder
Interventions: BIOLOGICAL: Immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial: Oral Health Package Law and Fluor Varnish Impact on Schoolchildren in Merida, Mexico
Status: RECRUITING
Conditions: Caries|Gum Disease
Interventions: DRUG: Fluoride varnish|DRUG: Fluoride toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of an Optimized Formulation of Omega 3 on the Composition of Atheromatous Plaques in Patients Requiring Carotid Endarterectomy
Status: UNKNOWN
Conditions: Carotid Endarterectomy
Interventions: DIETARY_SUPPLEMENT: VASCAZEN|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of NPF-08 in Patients Who Receive Colonoscopy
Status: COMPLETED
Conditions: Patients Who Receive Colonoscopy
Interventions: DRUG: NPF-08 （1-day treatment）|DRUG: NPF-08 （2-day split dose）|DRUG: Moviprep（1-day treatment）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Transcranial Magnetic Stimulation in Treatment of Attention Deficit/Hyperactivity Disorders
Status: UNKNOWN
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (Magstim, Rapid)|OTHER: Placebo Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of High Dose Vitamin D in Patient's With Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol 10,000 IU|DRUG: Cholecalciferol 400 IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Phase Ib/II Study of BAY 1000394 (Roniciclib) in Combination With Docetaxel in Second- or Third-line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Status: WITHDRAWN
Conditions: NSCLC (Non-Small Cell Lung Cancer)
Interventions: DRUG: BAY 1000394 (Roniciclib) in combination with docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Lazertinib With or Without Chemotherapy for Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Lazertinib+Pemetrexed+Carboplatin|DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Defibrotide Prophylaxis of Transplant Associated-Thrombotic Microangiopathy for Neuroblastoma
Status: WITHDRAWN
Conditions: Transplant-Associated Thrombotic Microangiopathy|Neuroblastoma|High-risk Neuroblastoma|Thrombotic Microangiopathies
Interventions: DRUG: Defibrotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Social Determinants of Health in Patients With Penetrating Trauma Injuries Before and During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Penetrating Injury|COVID-19|Social Determinants of Health
Interventions: DIAGNOSTIC_TEST: Postive SAR-CoV-2 PCR nasopharyngeal swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NIR-Fluorescence Guided Surgical Resection of Neoadjuvant Treated Localized Pancreatic Cancer Using SGM-101
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma
Interventions: PROCEDURE: Fluorescence-guided surgery using CEA-targeted fluorophore SGM-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Teaching People to be Self-compassionate Feasible and Acceptable for People Who Are Pre-diabetic
Status: COMPLETED
Conditions: PreDiabetes
Interventions: BEHAVIORAL: Self-compassion|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Immunotherapy Combinations in Participants With Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer|Nonsquamous Nonsmall Cell Neoplasm of Lung|Sensitizing EGFR Gene Mutation
Interventions: DRUG: Etrumadenant|DRUG: Zimberelimab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Rituximab|DRUG: Zanubrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph II Long Term/Low Dose Xeloda in Head and Neck Squamous Cell Carcinoma After Surgery, Radiation & or Chemo
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: capecitabine|PROCEDURE: Surgery, chemotherapy and/or radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Medical Device Usage and Evaluation|OTHER: Best Practice|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Types of Lingual Fixed Retainer Fabricated
Status: RECRUITING
Conditions: Malocclusion, Angle's Class
Interventions: DEVICE: Lingual retainer from Fiber|DEVICE: Lingual retainer from metal|DEVICE: Traditional retianer from braided
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT