pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cognitive Behaviour Therapy for Sleep Problems in Children With Autism Spectrum Disorder
Status: UNKNOWN
Conditions: Autism Spectrum Disorder|Cognitive Behaviour Therapy
Interventions: BEHAVIORAL: Cognitive behaviour therapy for insomnia|BEHAVIORAL: psychoeducation for ASD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemoradiation With Oxaliplatin and Fluorouracil (5FU) for Locally Advanced Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Oxaliplatin|DRUG: 5FU|RADIATION: Radiation|PROCEDURE: Surgery|DRUG: FOLFOX 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tenofovir Alafenamide Versus Placebo Added to a Failing Regimen Followed by Treatment With Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Atazanavir in HIV-1 Positive, Antiretroviral Treatment-Experienced Adults
Status: COMPLETED
Conditions: HIV|HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: TAF|DRUG: Placebo|DRUG: E/C/F/TAF|DRUG: Current failing ARV regimen|DRUG: ATV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Effects of Repeated Exposure to Low Levels of Concentrated Ambient Particles in Healthy Young Volunteers
Status: RECRUITING
Conditions: Air Pollution
Interventions: OTHER: PM exposure|OTHER: Filtered air exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Sublingual Immunotherapy (SLIT) Tablets in Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: 100 IR grass pollen allergen extract tablet|DRUG: 300 IR grass pollen allergen extract tablet|DRUG: 500 IR grass pollen allergen extract tablet|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHR1020 Plus Docetaxel as Compared to Placebo Plus Docetaxel in 2nd Line Non Squamous Non Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Squamous Non Small Cell Lung
Interventions: DRUG: SHR1020 plus Docetaxel|DRUG: Placebo plus Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating the Efficacy of Apremilast for the Treatment of Frontal Fibrosing Alopecia
Status: UNKNOWN
Conditions: Frontal Fibrosing Alopecia
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2, Multicenter, Open-Label Extension Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ABT-122
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis
Status: RECRUITING
Conditions: Renal Artery Stenosis Atherosclerotic|Secondary Hypertension Renal Arterial
Interventions: DRUG: Dopamine|DIAGNOSTIC_TEST: Fractional Flow Reserve, Renal|DEVICE: Renal artery stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MI and PreviDent Varnish on Non Cavitated Interproximal Lesions.
Status: UNKNOWN
Conditions: Prevention
Interventions: DRUG: MI Varnish|DRUG: PreviDent Varnish|DRUG: 1.23% APF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adult Study / OROS Methylphenidate Hydrochloride (HCL) (OROS MPH) in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: OROS MPH|DRUG: Placebo|DRUG: OROS MPH Tablets|DRUG: Placebo Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma
Status: COMPLETED
Conditions: Uveal Melanoma|Choroid Neoplasm
Interventions: BIOLOGICAL: ICON-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers|Adult|Pharmacokinetics
Interventions: DRUG: Ritlecitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Post-endodontic Pain After 3 Irrigation Regime
Status: COMPLETED
Conditions: Post-operative Pain
Interventions: PROCEDURE: Applied saline solution at 2.5 oC (Cryotherapy group)|PROCEDURE: Applied saline solution at 8oC (Cryotherapy )|PROCEDURE: Applied saline solution at room temperature (No cryotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Therapy in Patients With Resectable HCC Screened by a Multimodal Deep Learning Model
Status: NOT_YET_RECRUITING
Conditions: HCC
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Lenvatinib|DRUG: Tislelizumab|PROCEDURE: Liver resection|DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electromyography-Triggered Constraint-Induced Movement Cycling Therapy on Patients With Chronic Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: EMG-triggered CIMCT device|DEVICE: general cycling training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Imaging of High-grade Glioma Using 18F-fluoromethylcholine: a Tool for the Early Detection of Tumour Recurrence After Combined Radiochemotherapy?
Status: COMPLETED
Conditions: High-grade Glioma of the Brain
Interventions: RADIATION: PET images with 18F-fluoromethylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: DRUG: Inhaled amikacin|DRUG: Inhaled placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP)
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: DRUG: MSTT1041A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: H3N2 M2SR in Pediatric Population
Status: COMPLETED
Conditions: Influenza|Influenza Immunisation
Interventions: BIOLOGICAL: Influenza Virus Monovalent A/H3N2/Bris 10 M2SR Live Vaccine|OTHER: Placebo|BIOLOGICAL: Quadrivalent MDCK Inactivated Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Psychological Interventions for Complex PTSD And Schizophrenia-Spectrum Disorder: PICASSO Trial
Status: COMPLETED
Conditions: Psychosis|Complex Post-Traumatic Stress Disorder|Schizophrenia
Interventions: BEHAVIORAL: Affect Dysregulation intervention|BEHAVIORAL: Negative Self Concept intervention|BEHAVIORAL: Disturbed Relationships intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRF Based Dressing Versus AQUACEL® for Local Treatment of Skin Graft Donor Site
Status: WITHDRAWN
Conditions: Treatment of Skin Graft Donor Site
Interventions: OTHER: Half of the harvested area will be dressed with PRF dressing, and half with Aquacel®.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of BFR Training on Glycemic Control, Functional Activity and Quality of Life in Individuals With Pre-diabetes
Status: UNKNOWN
Conditions: PreDiabetes
Interventions: OTHER: Aerobic exercise with Blood flow restriction|OTHER: Aerobic exercise without Blood flow restriction|OTHER: Patient Education and dietary modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Cardiac Monitoring of Higher-Risk Emergency Department Syncope Patients After Discharge - A Pilot Study
Status: COMPLETED
Conditions: Syncope|Arrhythmia
Interventions: DEVICE: Cardiophone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Inoperable Non-Squamous NSCLC Stage III/IV: A Randomised Phase II Study With Bevacizumab Plus Erlotinib Or Gemcitabine/Cisplatin Plus Bevacizumab
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Erlotinib|DRUG: Bevacizumab|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Add-on Aripiprazole on Cardiometabolic Profile in Treatment Resistant Schizophrenia: RCT
Status: NOT_YET_RECRUITING
Conditions: Difference in the Change in Cardiovascular Risk in Treatment Resistant Schizophrenia
Interventions: DRUG: Aripiprazole 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Responsiveness of the Erectile Quality Scale to Vardenafil Flexible Dose vs Placebo in Males With Erectile Dysfunction (ED)
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Placebo|DRUG: Levitra (Vardenafil, BAY38-9456)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial on Precision Mental Health
Status: RECRUITING
Conditions: Mental Well-being|Mental Health Issue|Mental Health Wellness 1|Precision Mental Health
Interventions: BEHAVIORAL: Online guided transdiagnostic cognitive behavioural therapy|BEHAVIORAL: Online self-guided transdiagnostic cognitive behavioural therapy|BEHAVIORAL: Online self-guided mindfulness-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abuse Liability of Controlled-Release Oxycodone Formulations
Status: COMPLETED
Conditions: Substance-Related Disorders
Interventions: DRUG: Apo-Oxycodone CR®|DRUG: OxyNEO®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Minimally Invasive Total Knee Replacement in Improving Rehabilitation and Function
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Minimally Invasive Total Knee Arthroplasty [TKA Min]|PROCEDURE: Total Knee Arthroplasty (TKA) Traditional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concurrent Training and Metabolic Profile, Lung Function, Quality of Life and Stress
Status: COMPLETED
Conditions: Sedentary Lifestyle|Metabolic Disorders|Concurrent Exercise|Lung Function Decreased|Stress|Quality of Life|Office Worker
Interventions: BEHAVIORAL: Concurrent training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CCI-779 and Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma|Recurrent Renal Cell Cancer|Stage IV Renal Cell Cancer
Interventions: DRUG: CCI-779|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating Thought Problems in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Cognitive Adaptation Therapy (CAT)|BEHAVIORAL: Minimal Environmental Supports (MES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Molecular Variants Associated With Schizophrenia: Differential Analysis of Monozygotic Twins With Variable Phenotypic 22q11
Status: COMPLETED
Conditions: Di George Syndrome
Interventions: GENETIC: Molecular analyses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Embolization Trial for NeuroEndocrine Tumor Metastases To The Liver
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuroendocrine Tumor, Malignant|Liver Metastases
Interventions: DEVICE: Bland Embolization|COMBINATION_PRODUCT: Transarterial chemoembolization|COMBINATION_PRODUCT: Drug Eluting Beads Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elutax-SV Drug-eluting Balloons for Below-the-knee Treatment
Status: COMPLETED
Conditions: Critical Limb Ischemia|Peripheral Artery Disease
Interventions: DEVICE: Angioplasty Paclitaxel-eluted balloon catheter ELUTAX SV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epidemiological Study in Children and Adolescents With Chronic Hepatitis B
Status: COMPLETED
Conditions: Liver Diseases|Hepatitis, Chronic|Hepatitis, Viral, Human|Hepatitis|Virus Diseases|Digestive System Diseases|Hepatitis B, Chronic|Hepatitis B|DNA Virus Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics of Subcutaneous Dose of IMG-007 in Healthy Participants
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: IMG-007|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety and Efficacy Assessment of Hyaluronic Acid Dermal Filler With for the Treatment of Nasolabial Folds
Status: COMPLETED
Conditions: Aesthetics
Interventions: DEVICE: Hyaluronic acid dermal filler with lidocaine 0.3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Versus Progressive Robot-assisted Gait Training in People With Multiple Sclerosis and Severe Gait Disability
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: Lokomat device (Hocoma AG, Volketswil, Switzerland).|OTHER: Conventional walking training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction
Status: RECRUITING
Conditions: Smoking|Smoking Behaviors|Nicotine Dependence
Interventions: BEHAVIORAL: E-cigarette with 2.4% Nicotine with Menthol and Tobacco Flavors|BEHAVIORAL: E-cigarette with 2.4% Nicotine with Tobacco Flavor Only|BEHAVIORAL: E-cigarette with 5% Nicotine with Menthol and Tobacco Flavors|BEHAVIORAL: E-cigarette with 5% Nicotine with Tobacco Flavor Only|BEHAVIORAL: Tobacco Pouches with 3mg Nicotine with Menthol and Tobacco Flavors|BEHAVIORAL: Tobacco Pouches with 3mg Nicotine with Tobacco Flavor Only|BEHAVIORAL: Tobacco Pouches with 6mg Nicotine with Menthol and Tobacco Flavors|BEHAVIORAL: Tobacco Pouches with 6mg Nicotine with Tobacco Flavor Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long Term Efficacy, Safety and Immunogenicity of Enerceptan in Rheumatoid Arthritis ( GEMENE002 )
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Enteral Glutamine on Intestinal Permeability in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Enteral Nutrition|Intestinal Permeability
Interventions: DRUG: Glutamin|OTHER: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxyurea and EPO in Sickle Cell Disease
Status: RECRUITING
Conditions: Anemia, Sickle Cell|Sickle Cell Disease
Interventions: DRUG: Hydroxyurea|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Yoga on Student Mental Health
Status: COMPLETED
Conditions: Mental Health|Public Health|Depression, Anxiety|Sleep Problem|University Students
Interventions: BEHAVIORAL: Yoga group|BEHAVIORAL: yoga course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants >=12 Years Old With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclomethasone dipropionate|DRUG: Placebo|DRUG: Albuterol/salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability, and Efficacy of a Combination Treatment of LJN452 and CVC in Adult Patients With NASH and Liver Fibrosis
Status: COMPLETED
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: Tropifexor (LJN452)|DRUG: Cenicriviroc (CVC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Efficacy of Osteopathic Manipulative Treatment on Gait Dysfunction Following Knee Surgery
Status: COMPLETED
Conditions: Knee Arthroscopy|Knee Arthroplasty|Osteopathic Manipulative Treatment|Gait, Unsteady
Interventions: PROCEDURE: OMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
Status: TERMINATED
Conditions: Full-thickness Rotator Cuff Tear
Interventions: PROCEDURE: Best Repair of torn Rotator Cuff|DEVICE: InSpace™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of Gemcitabine, Capecitabine, and Bevacizumab in Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: combination of gemcitabine, capecitabine, and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Testosterone Gel Replacement on Fat Mass in Males With Low Testosterone Levels and Diabetes
Status: WITHDRAWN
Conditions: Hypogonadism|Diabetes
Interventions: DRUG: Testosterone gel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Investigating Four Nasal CPAP Systems in the Management of Apnea of Prematurity
Status: TERMINATED
Conditions: Continuous Positive Airway Pressure|Apnea of Prematurity|CPAP
Interventions: DEVICE: Stephanie (TM), Infant Flow (TM), Infant Flow advance (TM), Bubble CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Sleeve Gastrectomy and Cholecystectomy Are Safe in Obese Patients With Asymptomatic Cholelithiasis
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: PROCEDURE: patients with morbid obesity and gall bladder stone underwent concomitant laparoscopic cholecystectomy in the same setting during laparoscopic sleeve gastrectomy|PROCEDURE: patients with morbid obesity and gall bladder stone underwent laparoscopic sleeve gastrectomy without concomitant laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prednisone Timed-Release Tablet (TRT) Study: Modified-Release (MR) Formulation of Prednisone Compared to Standard Immediate-Release (IR) Prednisone in Participants With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MR Prednisone|DRUG: IR Prednisone|DRUG: Placebo - MR Prednisone|DRUG: Placebo - IR Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Candida Eradication and Serum Cidal Activity of Echinocandins
Status: COMPLETED
Conditions: Candidemia
Interventions: DRUG: micafungin|DRUG: Micafungin|DRUG: Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Far Infrared Irradiation for Control, Management and Treatment of Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: RADIATION: Far Infrared Radiation (5μm to 20μm wavelength)|RADIATION: Far infrared radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact on Birth Weight of Two Therapeutic Strategies (Insulin Therapy From the Beginning of Pregnancy vs. Insulin Therapy Initiated According to Fetal Growth Evaluated by Ultrasonography Measurements) in Pregnant Women With Monogenic Diabetes
Status: COMPLETED
Conditions: Maturity-Onset Diabetes of the Young
Interventions: OTHER: insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Radial Versus Femoral Arterial Access for Cerebral Angiography in Adolescents
Status: TERMINATED
Conditions: Procedural Related Injuries and Complications Nec|Patient Satisfaction
Interventions: PROCEDURE: transradial access for neuroangiography|PROCEDURE: transfemoral access for neuroangiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Deproteinized Bovine Bone in Alveolar Bone Critical Size Defect (>2cm) Secondary to Cyst Removal
Status: COMPLETED
Conditions: Maxillary Cyst
Interventions: BIOLOGICAL: Deproteinized bovine bone|DEVICE: granules of deproteinized bovine bone (Bio-Oss)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
Status: TERMINATED
Conditions: Diagnostic|Procedures and Surgeries on or Through Accessible Mucous Membranes|of the Nasal Cavities
Interventions: DRUG: Cocaine HCl 4% Topical Solution|DRUG: Cocaine HCl 10% Topical Solution|DRUG: Placebo Topical Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Status: NOT_YET_RECRUITING
Conditions: Inflammation|Cardiovascular Diseases|Myocarditis|Pericarditis|Myocardial Infarction|Heart Failure|Heart Diseases
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study on the Effect of Rosuvastatin Treatment on the Prevention of Thrombosis in Patients With Previous Thrombosis
Status: WITHDRAWN
Conditions: Venous Thrombosis|Pulmonary Embolism
Interventions: DRUG: Rosuvastatin (AZD4522)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Effects According to Patient-controlled Epidural Analgesia Modes in Patients Undergoing Open Gastrectomy
Status: UNKNOWN
Conditions: Open Gastrectomy With Gastric Cancer
Interventions: DEVICE: Apply CIPKA mode|DEVICE: Conventional mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exploring the Clinical Efficacy of Remote Management Applications Through Comprehensive Physical Therapy for Patients With Moderate to Severe Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: OSAHS|Oropharyngeal Muscle Training|Aerobic Exercise|Comprehensive Physical Therapy|M-health
Interventions: BEHAVIORAL: Myofunctional Therapy|BEHAVIORAL: Inspiratory Muscle Training|BEHAVIORAL: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: Febuxostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoreflex and Baroreflex Alterations Causing Postural Tachycardia Syndrome With Orthostatic Hyperpnea and Hypocapnia
Status: RECRUITING
Conditions: Postural Orthostatic Tachycardia Syndrome|Hypocapnia|Hyperventilation
Interventions: DIAGNOSTIC_TEST: Chemoreflex Testing|DIAGNOSTIC_TEST: Baroreflex testing|DIAGNOSTIC_TEST: Orthostatic stress testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Iloprost on Oxygenation During One-lung Ventilation for Lung Surgery
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Inhaled iloprost|DRUG: Distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Identify Biomarkers for Protein Intake
Status: COMPLETED
Conditions: Identify New Biomarkers in Blood or Urine After Consumption of Meat Protein, Dairy Protein and Grain Protein in Healthy Subjects.
Interventions: OTHER: Run in diet|OTHER: High meat protein diet|OTHER: High dairy protein diet|OTHER: High grain protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Trastuzumab in Treating Patients With Locally Advanced or Metastatic Gallbladder Cancer or Bile Duct Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Adenocarcinoma of the Extrahepatic Bile Duct|Adenocarcinoma of the Gallbladder|Malignant Neoplasm|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Morphine for Robotic-assisted Laparoscopic Hysterectomy.
Status: COMPLETED
Conditions: Opioid-Related Disorders
Interventions: PROCEDURE: Robotic-assisted hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma|Exfoliation Syndrome
Interventions: DRUG: travoprost/timolol fixed combination|DRUG: placebo (artificial tears)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Synbiotic Treatment in NAFLD
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab and/or Niraparib in Patients With Recurrent Endometrial and/or Ovarian Cancer With ARID1A Mutation
Status: RECRUITING
Conditions: Recurrent Endometrial Carcinoma|Recurrent Ovarian Carcinoma|ARID1A Gene Mutation
Interventions: DRUG: Bevacizumab|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating the ESDM in ASD Preschools in Israel
Status: UNKNOWN
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Early Start Denver Model|BEHAVIORAL: Eclectic preschool intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Status: RECRUITING
Conditions: Aortic Stenosis|Coronary Artery Disease|Coronary Stenosis
Interventions: PROCEDURE: Percutaneous Coronary Intervention (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams
Status: COMPLETED
Conditions: Neuroscience of Dreaming, Healthy
Interventions: DRUG: Naltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Propranolol on Post Stroke Immune Status and Infection
Status: UNKNOWN
Conditions: Stroke|Cerebrovascular Disorders|Ischemic Stroke|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Cardiovascular Diseases|Propranolol|Beta Blocker|Molecular Mechanisms of Pharmacological Action|Immunologic Factors|Physiological Effects of Drugs
Interventions: DRUG: Propranolol|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Phytonutrients Upon Muscle Perfusion in Response to Feeding
Status: COMPLETED
Conditions: Biological Aging
Interventions: OTHER: Catechin Cohort 1|OTHER: Curcuminoid Cohort 2|OTHER: Flavonoid Cohort 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: CP-690,550|DRUG: CP-690,550|DRUG: Placebo|DRUG: CP-690,550|DRUG: Placebo|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of mgso4 on Oxygenation and Lung Mechanics in Morbidly Obese Patients During Bariatric Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: mg sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of XL147 (SAR245408) in Combination With Erlotinib in Adults With Solid Tumors
Status: COMPLETED
Conditions: Cancer|Non-small Cell Lung Cancer
Interventions: DRUG: XL147 (SAR245408)|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
Status: TERMINATED
Conditions: Mitral Valve Insufficiency|Heart Failure
Interventions: PROCEDURE: Surgical mitral valvuloplasty with placement of annular ring (SMVR)|DRUG: Optimal medical therapy (OMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Calcipotriol Plus Betamethasone Dipropionate Gel in Scalp Psoriasis
Status: COMPLETED
Conditions: Psoriasis of Scalp
Interventions: DRUG: Calcipotriol plus betamethasone dipropionate (LEO80185 gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pain Assessment During Mandibular Nerve Block Injection With the Aid of Dental Vibe Tool in Pediatric Dental Patients
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DEVICE: DentalVibe|DRUG: Topical Benzocaine 20%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Dose Finding Study of Eribulin Mesylate and Cetuximab For Patients With Advanced Head and Neck and Colon Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Colon Cancer
Interventions: DRUG: Head and neck|DRUG: Colon- Closed as of May 2014
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxycycline PEP for Prevention of Sexually Transmitted Infections Among Kenyan Women Using HIV PrEP
Status: COMPLETED
Conditions: HIV Infections|HIV/AIDS|Neisseria Gonorrheae Infection|Chlamydia Trachomatis Infection|Syphilis Infection
Interventions: DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial of Topical ABL01 Treatment of Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis of Toenail
Interventions: DEVICE: ABL01|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venlafaxine ER Phase 3 Study for Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: venlafaxine ER 75 mg/day (fixed dose)|DRUG: venlafaxine ER 75 mg/day to 225 mg/day (flexible dose)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PCSK9 Inhibitor on ACS Patients With Multivessel Disease and Relatively Low LDL-C Level in Chinese Population
Status: UNKNOWN
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Repatha or Praluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-market Clinical Follow up of the Genio™ System for the Treatment of Obstructive Sleep Apnea in Adults
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Genio(TM) system therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Bioequivalence Study of 2 Oral Progesterone Soft Capsules 200 mg in 48 Healthy Female Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Progesterone 200 mg Soft Capsule (JSC "Farmak", Ukraine)|DRUG: Utrogestan® 200 mg Soft Capsule (Manufacturer by: Cyndea Pharma, S.L., Spain, MAH: Laboratoires Besins International, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of CardiolRx on Myocardial Recovery in Patients With Acute Myocarditis
Status: RECRUITING
Conditions: Acute Myocarditis
Interventions: DRUG: CardiolRx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects on CK, RPE, VAS Scale and Physical Performance of Three Recovery Methods in Elite Basketball Players
Status: COMPLETED
Conditions: Cold-water Immersion|Protein-carbohydrates Supplementation|Active Recovery|Placebo
Interventions: PROCEDURE: Cold-water immersion|PROCEDURE: Protein-carbohydrates supplementation|PROCEDURE: Active recovery|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sotagliflozin in Young Adult Patients With Type 1 Diabetes Mellitus and Elevated Hemoglobin A1C
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Accelerometer-Based Neuromuscular Monitoring Reliability to Exclude Postoperative Residual Paralysis
Status: COMPLETED
Conditions: Postoperative Residual Paralysis
Interventions: DRUG: sugammadex|DRUG: Sodium chloride solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparison of the Cuff Pressure of TaperGuard and Cylindrical- Endotracheal Tube During Laparoscopic Surgery
Status: COMPLETED
Conditions: Cuff Pressure
Interventions: DEVICE: Cylindrical endotracheal tube|DEVICE: TaperGaurd endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme of Brain
Interventions: DRUG: Cisplatin Plus Temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer
Status: TERMINATED
Conditions: Malignant Neoplasm
Interventions: DRUG: Dexamethasone|OTHER: Placebo|OTHER: Questionnaire|OTHER: Quality-of-Life Assessment|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Gemcitabine and Carboplatin in the Treatment of Metastatic or Recurrent Cholangiocarcinoma/Gallbladder Cancer
Status: COMPLETED
Conditions: Cholangiocarcinoma|Gallbladder Cancer
Interventions: DRUG: Gemcitabine|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Ifosfamide, and Vinorelbine Tartrate in Treating Young Patients With Hodgkin's Lymphoma That is Recurrent or Did Not Respond to Previous Therapy
Status: COMPLETED
Conditions: Adult Lymphocyte Depletion Hodgkin Lymphoma|Adult Lymphocyte Predominant Hodgkin Lymphoma|Adult Mixed Cellularity Hodgkin Lymphoma|Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma|Adult Nodular Sclerosis Hodgkin Lymphoma|Childhood Lymphocyte Depletion Hodgkin Lymphoma|Childhood Lymphocyte Predominant Hodgkin Lymphoma|Childhood Mixed Cellularity Hodgkin Lymphoma|Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma|Childhood Nodular Sclerosis Hodgkin Lymphoma|Recurrent Adult Hodgkin Lymphoma|Recurrent/Refractory Childhood Hodgkin Lymphoma|Stage I Adult Hodgkin Lymphoma|Stage I Childhood Hodgkin Lymphoma|Stage II Adult Hodgkin Lymphoma|Stage II Childhood Hodgkin Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Childhood Hodgkin Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Childhood Hodgkin Lymphoma
Interventions: DRUG: ifosfamide|DRUG: bortezomib|DRUG: vinorelbine tartrate|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Creatine Monohydrate Supplementation on Androgens and Global Hair Assessments
Status: WITHDRAWN
Conditions: Dihydrotestosterone|Testosterone|Hair Loss
Interventions: DIETARY_SUPPLEMENT: Creatine Monohydrate Supplementation|DIETARY_SUPPLEMENT: Placebo Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adequate Additional Bronchial Cuff Volume to Achieve Blood-tight Seal After Air-tight Seal in Double Lumen Tube
Status: UNKNOWN
Conditions: Preventing Blood Leakage of Bronchial Cuff
Interventions: PROCEDURE: 39 Fr double lumen tube group|PROCEDURE: 37 Fr double lumen tube group|PROCEDURE: 35 Fr double lumen tube group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PERIOPERATIVE MYOCARDIAL DAMAGE IN ROBOT-ASSISTED SURGERY
Status: NOT_YET_RECRUITING
Conditions: Myocard Injury After Non Cardiac Surgery|Robotic Assisted Laparoscopic Radical Prostatectomy
Interventions: DIAGNOSTIC_TEST: high sensitive troponin I
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Placebo-Controlled Multi-Centre Double-Blind Trial for Adults With Extended-Release Methylphenidate for ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: methylphenidate hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Families on Track: A Digital Health Behavioral Intervention for Parents Seeking Treatment for Their Child With Obesity
Status: COMPLETED
Conditions: Obesity|Childhood Obesity|Hypertension|Diabetes|Dyslipidemia
Interventions: BEHAVIORAL: Families on Track Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ph 2 Intensification Regimen for Previously Untreated, Resectable, Advanced Squamous Cell Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cisplatin|DRUG: Paclitaxel|RADIATION: Intensity-Modulated Radiation Therapy (IMRT) External Beam Radiation|PROCEDURE: Triple endoscopy and biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cortical Plasticity in a Complex Intervention for Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: PROCEDURE: Specific Autoregulation Therapy (SART)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Metabolic Effects of Carbohydrate Restriction at Varying Energy Levels
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: nEB Diet, followed for 36 hours|OTHER: LC25 Diet, followed for 36 hours|OTHER: LCEB Diet, followed for 36 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: BL-300-PFM04|DEVICE: OPTI-FREE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT