pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Differing Taxanes/Taxane Combinations on the Outcome of Patients With Operable Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects on the Personalized Rehabilitation Service in Patients With Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Breast Neoplasms|Breast Cancer Female|Lymphedema
Interventions: BEHAVIORAL: Personalized health care service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of BHV-4157 in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: troriluzole|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Process for the Manufacture of Stem Cells Isolated From the Nasal Cavity for Innovative Cell Therapy of Traumatized Peripheral Nerves
Status: UNKNOWN
Conditions: Septoplasty|Turbinoplasty
Interventions: PROCEDURE: biopsy of mucosa's olfactory
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Polio|Haemophilus Infection
Interventions: BIOLOGICAL: Diphtheria and Tetanus Toxoids and Acellular Pertussis (DAPTACEL®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CRRT Versus Plasmapheresis in Aluminum Phosphide Poisoning
Status: NOT_YET_RECRUITING
Conditions: Aluminium Phosphide Poisoning
Interventions: OTHER: Routine management|DEVICE: CRRT|DEVICE: PPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Springfusor for Administration of Magnesium Sulphate in Preeclampsia and Eclampsia
Status: UNKNOWN
Conditions: Preeclampsia and Eclampsia
Interventions: DEVICE: Springfusor|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Scapular Stabilization Exercises on Scapular Muscles Strength and Kyphosis Index in Smartphone Users
Status: UNKNOWN
Conditions: Muscle Weakness|Smartphone Addiction
Interventions: OTHER: Scapular Stabilization exercises|OTHER: Postural correction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Myofascial Relaxation on Individuals With Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Conventional Treatment|OTHER: Myofascial Release Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Tramacet Versus Percocet in Post Surgical Patients
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: DRUG: Tramacet|DRUG: Percocet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Doses of Olmesartan Medoxomil and Amlodipine on Vascular Markers in Hypertensive Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Hypertension
Interventions: DRUG: Olmesartan medoxomil tablets low dose|DRUG: Olmesartan medoxomil tablets high dose|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating of the Impact of a Connected and Non-intrusive Device in Improving the Screening of Sleep Apnea Syndrome and the Addressing of Potentially Pathological Patients in Hospital Environment
Status: RECRUITING
Conditions: Sleep Apnea Syndromes|Metabolic Syndrome|Diabetes|Obese
Interventions: DEVICE: WITHINGS Sleep Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: RCT of Vibration Effect on Vertebral BMD in Disabled Patients
Status: UNKNOWN
Conditions: Vibration Therapy|Wheelchair|Osteoporosis
Interventions: DEVICE: Low-magnitude High-frequency Vibration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Combined With Early Stereotactic Body Radiation Therapy to the Primary Tumor in Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor|DEVICE: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IN.PACT™ AV Access IDE Study
Status: COMPLETED
Conditions: Arteriovenous Fistula Stenosis|Arteriovenous Fistula Occlusion|Arteriovenous Fistula|Fistula
Interventions: DEVICE: IN.PACT AV DCB|DEVICE: Standard Balloon Angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Of An Oral Tyrosine Kinase Inhibitor Of VEGFR-2 To Treat Small-Volume Ovarian, Peritoneal, Fallopian Tube Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms|Fallopian Tube Neoplasms
Interventions: DRUG: CP-547,632
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke （Japan Alteplase Clinical Trial Ⅱ：J-ACT Ⅱ）
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Alteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Valiant Mona LSA Thoracic Stent Graft System in Descending TAA and Chronic Dissections
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm, Thoracic, Chronic Type B Dissection
Interventions: DEVICE: Valiant Mona LSA Thoracic Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Botulinum Toxin A Alone Versus Botulinum Toxin A With Hydrodistension for Treatment of Overactive Bladder
Status: TERMINATED
Conditions: Overactive Bladder
Interventions: PROCEDURE: Hydrodistention|DRUG: Botulinum toxin-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blinded Study of Simvastatin 20 mg/Day Versus Vytorin 10/20 in Subjects With Lipid Profiles Not Meeting Current NCEP Guidelines, Following a Low-Carbohydrate Diet
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DRUG: simvastatin 20 mg/ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluate the Efficacy and Safety of GV1001 in Patients With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)
Interventions: DRUG: GV1001 placebo|DRUG: Proscar placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Teduglutide Effectiveness in Parenteral Nutrition (PN)-Dependent Short Bowel Syndrome (SBS) Subjects
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: teduglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tezosentan in Patients With Pulmonary Arterial Hypertension
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: ACT-050089|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of IV Acetaminophen in Acute Post-Operative Pain Control in Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP) Patients
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DRUG: IV acetaminophen|DRUG: IV normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Amlodipine Versus Amlodipine Combined With Atorvastatin on the Coronary Vasospastic Angina
Status: UNKNOWN
Conditions: Quality of Life
Interventions: DRUG: Caduet 10Mg-20Mg Tablet|DRUG: NorvasC® 10 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of a Combination of Bendamustine, Rituximab and Lenalidomide in Patients With Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Bendamustine, Rituximab, Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Sprint Training in Normobaric Hypoxia
Status: COMPLETED
Conditions: Hypoxia
Interventions: DEVICE: Normobaric Hypoxia Exposure|DEVICE: Normobaric Normoxia Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Biobehavioral Pathways Underlying Alcohol Use and Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder|Liver Diseases
Interventions: BEHAVIORAL: Brief Motivational Interviewing with Personalized Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Clinical Study of Recombinant Erythropoiesis Stimulating Protein Injection (rESP) in the Treatment of Anemia in Hemodialysis Patients With Chronic Renal Failure
Status: UNKNOWN
Conditions: Kidney Failure, Chronic|Hemodialysis
Interventions: DRUG: Human Erythropoiesis Injection (CHO cell)|DRUG: Recombinant Erythropoiesis Stimulating Protein Injection(CHO cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 4 Study With Tamsulosin OCAS to Assess Nighttime Voiding.
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin OCAS|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Title: Efficacy and Safety of Point- Of-care Procalcitonin Test to Reduce Antibiotic Exposure in VAP
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DIAGNOSTIC_TEST: PCT-guided group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.
Status: COMPLETED
Conditions: Solid Tumour Neoplastic Meningitis|Brain Metastases
Interventions: DRUG: Whole Brain Radio Therapy (WBRT) with sequential Depocyte|DRUG: Whole brain radiotherapy (WBRT) with concomitant Depocyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction of the Anterior Cruciate Ligament(ACL-R) in the 30+-Year Old Assessed by Patient Reported Outcome Measures(PRO) Using the Nationwide Danish Knee Ligament Reconstruction Registry
Status: COMPLETED
Conditions: Cruciate Ligament Rupture
Interventions: PROCEDURE: Patient age at time of procedure of reconstruction of ACL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Positron Emission Tomography (PET) Imaging of Participants With Confirmed Prostate Cancer Using 64Cu-SAR-bisPSMA (PROPELLER)
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: 64Cu-SAR-bisPSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cough Reflex Sensitivity and Bronchial Hyper-responsiveness
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Chronic Cough|Broncho-hyperreactivity
Interventions: PROCEDURE: Cough Reflex Sensitivity|PROCEDURE: Methacholine Challenge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dronedarone in Pacemakers Patients With Paroxysmal Atrial Fibrillation
Status: UNKNOWN
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DRUG: Dronedarone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the BREATHE Asthma Intervention Trial
Status: COMPLETED
Conditions: Asthma Chronic|Health Behavior
Interventions: BEHAVIORAL: BREATHE|OTHER: Attention Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Dose Proportionality and Bioavailability Assessment of Buprenorphine Transdermal Delivery System Second Generation Patches
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Second generation BTDS patch|DRUG: First generation BuTrans patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Phase 1 Study in Patients With Advanced and/or Refractory Solid Malignancies to Evaluate the Safety of ATOR-1015
Status: COMPLETED
Conditions: Solid Tumor|Neoplasms
Interventions: BIOLOGICAL: ATOR-1015
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of FMT for Acute Intestinal GVHD After Allo-HSCT
Status: UNKNOWN
Conditions: Acute Graft Versus Host Disease in Intestine
Interventions: BIOLOGICAL: Fecal Microbiota Transplantation|DRUG: drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Tractions vs. Placebo Tractions in Patients With Cervical Radiculopathy
Status: RECRUITING
Conditions: Radiculopathy|Cervical
Interventions: OTHER: Intensive cervical traction protocol|OTHER: Intensive cervical traction protocol - placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer
Status: COMPLETED
Conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Biomechanical Exercise Program for Knee OA
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Biomechanical Exercise (BE)|OTHER: Traditional Exercise (TE)|OTHER: Meditation Control (M)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Compare the Pharmacokinetics of a Single Oral Dose of TC-5214 in Subjects With Renal Impairment and With Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Healthy Volunteers|Patients|Pharmacokinetics|Renal Impairment
Interventions: DRUG: TC-5214
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Is Video-assisted Thoracoscopic Lobectomy a Clinical Alternative for Surgically Resectable Pathologic N2 NSCLC Patients
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: PROCEDURE: VATS lobectomy|PROCEDURE: Thoracotomy lobectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of 68Ga-PSMA-11 PET Scans in People With Brain Tumors
Status: RECRUITING
Conditions: High-grade Glioma|Brain Metastases|Brain Metastases, Adult
Interventions: DIAGNOSTIC_TEST: 68Ga-PSMA-11 PET Scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Practical Advantages of Single-port Over Three-port Laparoscopic Appendectomy in Children
Status: COMPLETED
Conditions: Appendicitis
Interventions: PROCEDURE: Single-port laparoscopic appendectomy|PROCEDURE: Three-port laparoscopic appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Balance Changes After Chiropractic Adjustments in Health Adults.
Status: COMPLETED
Conditions: Postural Balance|Musculoskeletal Manipulation
Interventions: OTHER: Upper extremity manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nimotuzumab Plus S1 Versus Placebo Plus S1 as Maintenance Treatment in Patients With Unresectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Unresectable Pancreatic Cancer
Interventions: DRUG: Nimotuzumab plus S1|DRUG: Placebo plus S1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)
Status: RECRUITING
Conditions: Advanced Cancer|Anal Carcinoma|Anal Cancer|Biliary Cancer|Cholangiocarcinoma|Bile Duct Cancer|Neuroendocrine Tumor|Carcinoid Tumor|Endometrial Carcinoma|Endometrial Cancer|Cervical Carcinoma|Cervical Cancer|Vulvar Carcinoma|Vulvar Cancer|Small Cell Lung Carcinoma|Small Cell Lung Cancer (SCLC)|Mesothelioma|Thyroid Carcinoma|Thyroid Cancer|Salivary Gland Carcinoma|Salivary Gland Cancer|Salivary Cancer|Parotid Gland Cancer|Advanced Solid Tumors|Colorectal Carcinoma
Interventions: BIOLOGICAL: pembrolizumab|BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Dipyridamole Induce Protection Against Ischemia and Reperfusion Injury in Patients Undergoing Elective Coronary Artery Bypass Grafting (CABG)?
Status: COMPLETED
Conditions: Cardiovascular Disease|Ischemic Heart Disease
Interventions: DRUG: Dipyridamole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL)
Status: RECRUITING
Conditions: Hot Flashes|Prostate Cancer|Acupuncture
Interventions: DEVICE: Acupuncture|DEVICE: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Patient Use and Perception of the Travatan Dosing Aid
Status: COMPLETED
Conditions: Glaucoma
Interventions: DEVICE: Fully functional monitoring device|DEVICE: Partially functional monitoring device|DEVICE: Non-functional monitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma
Status: RECRUITING
Conditions: Lymphoma
Interventions: DRUG: Magnesium Chloride-based Lotion|OTHER: Quality-of-Life Assessment|BEHAVIORAL: Special Diet Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alendronate Compared to Metformin in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: SRP plus Placebo Gel|DRUG: SRP plus Alendronate gel|DRUG: SRP plus Metformin gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Polymorphisms of Interleukins, Glypican, and Human Leukocyte Antigen Genes and Treatment Response in Multiple Sclerosis.
Status: UNKNOWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: GENETIC: Polymorphism of Interleukins, Glypican, and Human Leukocyte Antigen Genes.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Care Planning for Older Persons With Multiple Conditions: Encouraging a Tailored Approach (COMET): Stage II
Status: COMPLETED
Conditions: Polypharmacy
Interventions: OTHER: COMET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dasatinib in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IVA Salivary Gland Cancer|Stage IVA Squamous Cell Carcinoma of the Larynx|Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVA Verrucous Carcinoma of the Larynx|Stage IVA Verrucous Carcinoma of the Oral Cavity|Stage IVB Salivary Gland Cancer|Stage IVB Squamous Cell Carcinoma of the Larynx|Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVB Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVB Verrucous Carcinoma of the Larynx|Stage IVB Verrucous Carcinoma of the Oral Cavity|Stage IVC Salivary Gland Cancer|Stage IVC Squamous Cell Carcinoma of the Larynx|Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IVC Squamous Cell Carcinoma of the Oropharynx|Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IVC Verrucous Carcinoma of the Larynx|Stage IVC Verrucous Carcinoma of the Oral Cavity|Tongue Cancer
Interventions: DRUG: dasatinib|PROCEDURE: pharmacological study|PROCEDURE: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-dose Pharmacokinetics and Relative Bioavailability of an Oral Suspension and Two Tablet Formulations of BIA 2-093
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: BIA 2-093|DRUG: BIA 2-093|DRUG: BIA 2-093
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observed Pharmacokinetic of Piperacillin/Tazobactam Compared to Amikacin in ICU
Status: UNKNOWN
Conditions: Septic Shock|Sepsis|Sepsis Syndrome
Interventions: BIOLOGICAL: Plasma dosage of amikacin, piperacillin and tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation and Evaluation of an Electronic Alert to Encourage Targeted Screening for HIV Infection at Foch Hospital According to Socio-demographic Criteria
Status: COMPLETED
Conditions: HIV Testing
Interventions: OTHER: "POP-UP" electronic alert|DIAGNOSTIC_TEST: Serology HIV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer
Status: RECRUITING
Conditions: Urothelial Bladder Cancer|Muscle-Invasive Bladder Cancer
Interventions: DIAGNOSTIC_TEST: mpMRI + Diagnostic TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Ascending Dose Study of AMG 570 in Healthy Subjects
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: AMG 570|BIOLOGICAL: AMG 570 Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|DRUG: vorinostat|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.
Status: COMPLETED
Conditions: Hemochromatosis, Type 4|Ferroportin Disease|Dysmetabolic Hepatosiderosis|Diagnosis
Interventions: DRUG: iron fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers
Status: WITHDRAWN
Conditions: Advanced Solid Tumor|Metastatic Cancer|HER2-positive Breast Cancer|HER2-positive Gastric Cancer|HER-2 Protein Overexpression|Esophageal Cancer|Ovarian Cancer|Endometrium Cancer|Bladder Cancer|Pancreatic Cancer|Colorectal Cancer|Non Small Cell Lung Cancer|EGF-R Positive Non-Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma|Triple Negative Breast Cancer|Cervical Cancer|Sarcoma
Interventions: BIOLOGICAL: SNK01|DRUG: Trastuzumab|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Obliquity Rehabilitation in Stroke Patients Using Robotically Generated Force Fields
Status: TERMINATED
Conditions: Gait Re-training in Healthy Subjects|Gait Re-training in Stroke Survivors
Interventions: DEVICE: Robotic Gait Rehabilitation (RGR) Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Preoperative Exercise on Postoperative Outcome in AAA Patients: Pilot Study
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal|Surgery
Interventions: OTHER: Preoperative exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of an APP in Improving Treatment Adherence in Hypertensive Patients in Hypertension Ambulatory
Status: UNKNOWN
Conditions: Blood Pressure|Adhesion
Interventions: OTHER: App hypercross group|OTHER: without App hypercross group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: BEACON - ABC in Recurrent Platinum Resistant HGSOC
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stalevo in Early Wearing-Off Patients
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: DRUG: Stalevo (levodopa/carbidopa/entacapone)|DRUG: Levodopa/carbidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Prophylactic Octreotide to Pancreatic Exocrine Secretion
Status: UNKNOWN
Conditions: Periampullary Tumors
Interventions: DRUG: Octreotide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CEND-1 Injection (QLC12102) in Patients With Advanced Metastatic Pancreatic Ductal Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: CEND-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programmed Intermittent Epidural Bolus (PIEB) Techniques for Labour Analgesia
Status: NOT_YET_RECRUITING
Conditions: Labor Pain|Obstetric Pain|Analgesia
Interventions: DRUG: Levobupivacaine and Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gentamicin Bladder Instillation Trial
Status: UNKNOWN
Conditions: Urinary Tract Infections
Interventions: DRUG: Gentamicin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Salvational Intervention for Reducing AECOPD Under Severe Air Pollution
Status: COMPLETED
Conditions: COPD Exacerbation|Air Pollution
Interventions: DRUG: Budesonide/formoterol|DRUG: tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ACL SNNAP Trial: ACL Surgery Necessity in Non Acute Patients
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Injury
Interventions: OTHER: Non-Surgical Management (Rehabilitation)|PROCEDURE: Surgical Management (Reconstruction)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
Status: RECRUITING
Conditions: Cognition|Gut Microbiome
Interventions: DIETARY_SUPPLEMENT: Probiotic Supplement|DEVICE: Transcutaneous Vagal Nerve Stimulation (tVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Six-month Phase 2 Study of Oral hPTH(1-34) (EBP05) in Postmenopausal Women With Low Bone Mass
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: EBP05|DRUG: Placebo of EBP05
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Treatment for Permanent Molars Affected With Molar-incisor Hypomineralization Defects
Status: ACTIVE_NOT_RECRUITING
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: SDF|PROCEDURE: HVGIC restoration|PROCEDURE: SSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-course Regimens for the Treatment of Pulmonary Tuberculosis
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary|Tuberculosis Infection
Interventions: DRUG: Rifabutin|DRUG: Delamanid|DRUG: Bedaquiline|DRUG: Moxifloxacin|DRUG: Pyrazinamide|DRUG: Isoniazid|DRUG: Rifampin|DRUG: Ethambutol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of IBI110 in Combination With Sintilimab Versus Sintilimab Alone in Neoadjuvant and Adjuvant Therapy of Radically Resectable Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: IBI110|DRUG: sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Cocaine, Nasal Oxytocin, and Maternal Psychophysiology
Status: COMPLETED
Conditions: Substance Abuse Problem|Pregnancy
Interventions: DRUG: Syntocinon treatment|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV Melanoma
Status: COMPLETED
Conditions: Unresectable Stage III|Stage IV Melanoma
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drainage After Rectal Excision for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer Surgery|Randomized Clinical Trial|Multicenter Study|Pelvic Drainage
Interventions: PROCEDURE: Laying and management of the drain (strictly randomized arm with drainage)|PROCEDURE: No pelvic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intervention to Retain HIV-positive Patients in Medical Care
Status: COMPLETED
Conditions: Primary Care Appointment Keeping
Interventions: BEHAVIORAL: Enhanced contact plus behavioral skills|BEHAVIORAL: Enhanced contact only|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease.
Status: RECRUITING
Conditions: Crohn's Disease
Interventions: DRUG: Risankizumab SC|DRUG: Placebo for risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Recurrent Head and Neck Squamous Cell Carcinoma|Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Pembrolizumab|RADIATION: Proton Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of a Telephone Weight Loss, Nutrition, Exercise Study
Status: COMPLETED
Conditions: Weight Loss|Weight, Body
Interventions: BEHAVIORAL: TALK study group|BEHAVIORAL: TALK control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of VAL401 in the Treatment of Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Adenocarcinoma
Interventions: DRUG: VAL401
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Tolerability of EVI-01 Intra-Articular Injection in Osteoarthritis of the Knee
Status: RECRUITING
Conditions: Osteoarthritis|Osteoarthritis, Knee
Interventions: DEVICE: EVI-01|DEVICE: Active comparator Synvisc-One
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye.
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: SI-614|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Henagliflozin for Weight Loss in Obesity Without Diabetes
Status: NOT_YET_RECRUITING
Conditions: Obese|Weight Loss|Pre-diabetes
Interventions: DRUG: Henagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Icotinib Versus Placebo as Adjuvant Therapy in EGFR-mutant Lung Adenocarcinoma
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer|Adenocarcinoma
Interventions: DRUG: Icotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Penetration of Ceftobiprole Into Soft Tissue Determined by Microdialysis in Healthy Volunteers
Status: COMPLETED
Conditions: Staphylococcal Skin Infections|Streptococcal Infections
Interventions: DRUG: Ceftobiprole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-exposure Prophylaxis (PrEP) Adherence Enhancement Guided by iTAB and Drug Levels for Women
Status: COMPLETED
Conditions: HIV Prevention
Interventions: BEHAVIORAL: Text Messaging|BEHAVIORAL: Adherence Counseling|DRUG: Daily Oral PrEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study of the Use of ULTRABRAID PLUS SUTURE in the Repair of Tears of the Rotator Cuff
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: ULTRABRAID PLUS SUTURE|DEVICE: ULTRABRAID SUTURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the Pharmacokinetics and Bioequivalence of Two Flupentixol Formulations
Status: COMPLETED
Conditions: Bioequivalence Study in Healthy Subjects
Interventions: DRUG: 0.5 mg Flupentixol film-coated tablet (test treatment)|DRUG: 1 mg Flupentixol film-coated tablet (test treatment)|DRUG: 5 mg Flupentixol film-coated tablet (test treatment)|DRUG: 0.5 mg Flupentixol coated tablet (reference treatment)|DRUG: 1 mg Flupentixol coated tablet (reference treatment)|DRUG: 5 mg Flupentixol coated tablet (reference treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stability, Marginal Bone Loss and Occlusal Load Analysis of PEEK Abutment Supported on Short Implant
Status: UNKNOWN
Conditions: Marginal Bone Loss and Loss of Osteointegration of Short Implant
Interventions: OTHER: customization of abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19
Status: COMPLETED
Conditions: COVID-19|Corona Virus Infection|SARS-CoV 2|Coronavirus|Coronavirus Infection
Interventions: DRUG: ArtemiC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Vancomycin CVVHDF With oXiris Membrane
Status: NOT_YET_RECRUITING
Conditions: AKI - Acute Kidney Injury
Interventions: DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: Digital app and information system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of LY900014 in a Medtronic Pump
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy or Combination Chemotherapy in Treating Patients With Clinically or Radiologically Progressive Low-Grade Gliomas
Status: COMPLETED
Conditions: Primary Central Nervous System Neoplasms
Interventions: DRUG: vincristine, carboplatin|DRUG: vincristine, carboplatin, etoposide|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of PACV Administration on Vaccine Hesitancy
Status: COMPLETED
Conditions: Evaluating Impact of PACV on Vaccine Hesitancy Among Parents of Newborns
Interventions: BEHAVIORAL: PACV survey|BEHAVIORAL: Placebo survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Pilot Study Evaluating the Potential of 18F Fluorodeoxyglucose PET-CT Imaging in Diagnosing Cardiac Rejection.
Status: NOT_YET_RECRUITING
Conditions: Cardiac Transplant Rejection
Interventions: RADIATION: 18F-Fluorodeoxyglucose Positron Emission Tomography-computed Tomography (18F-FDG PET CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Peripheral and Macular Retinal Vascular Perfusion and Leakage in DME and RVO
Status: COMPLETED
Conditions: Retinal Vein Occlusion|Diabetic Macular Edema|Branch Retinal Vein Occlusion|Central Retinal Vein Occlusion
Interventions: DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotypic and Genetic Properties in Males at Risk for X-linked Hypohidrotic Ectodermal Dysplasia: Evaluation of an Early Diagnosis Technology and Tests to Assess Nutritional Status
Status: COMPLETED
Conditions: X-linked Hypohidrotic Ectodermal Dysplasia|Hypohidrotic Ectodermal Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness-based Program for Children With Disruptive Behavior Disorder
Status: COMPLETED
Conditions: Disruptive Behavior Disorder|Oppositional Defiant Disorder|Attention Deficit and Disruptive Behavior Disorders
Interventions: BEHAVIORAL: Mindfulness-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Hormones and Roux en Y Gastric Bypass
Status: RECRUITING
Conditions: Obesity|Type 2 Diabetes
Interventions: PROCEDURE: Roux en Y Gastric Bypass Surgery|OTHER: Gut hormone infusion|OTHER: Placebo infusion|OTHER: Very low calorie diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Afatinib|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cisplatin|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tegoprazan in GERD Patients With Nighttime Heartburn
Status: RECRUITING
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Tegoprazan|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT