pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination of Carboplatin, Gemcitabine, and Capecitabine in Patients With Carcinoma of Unknown Primary Site
Status: TERMINATED
Conditions: Carcinoma of Unknown Primary
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: CACIPLIQ20 in Wound Healing in Subjects With Epidermolysis Bullosa
Status: RECRUITING
Conditions: Epidermolysis Bullosa Dystrophica|Epidermolysis Bullosa, Junctional
Interventions: DEVICE: CACIPLIQ20|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quality and Biologic Characteristics of Red Blood Concentrates Obtained From Individuals With Elevated Ferritin.
Status: ENROLLING_BY_INVITATION
Conditions: Hereditary Hemochromatosis|Hyperferritinemia
Interventions: PROCEDURE: Venipuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) for Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Status: COMPLETED
Conditions: Ulcerative Colitis (UC)
Interventions: DRUG: Placebo|DRUG: Upadacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The FundoRingOAGB Versus Non-wrapping (Non-banded) Standard Method of Laparoscopic One Anastomosis Gastric Bypass
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: FundoRingOAGB|PROCEDURE: OAGB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Voice for Ergonomics as a Preventive Approach for Work-related Musculoskeletal Disorders in Masonry Apprentices
Status: UNKNOWN
Conditions: Work Related Musculoskeletal Disorders
Interventions: BEHAVIORAL: Ergonomics training and/or Safety Voice training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF
Status: TERMINATED
Conditions: Pancreatic Fistula
Interventions: DRUG: Piperacillin/Tazobactam|DRUG: Amoxicillin/ Clavulanic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Focused Ultrasound to Promote Immune Responses for Undifferentiated Pleomorphic Sarcoma
Status: RECRUITING
Conditions: Undifferentiated Pleomorphic Sarcoma
Interventions: DEVICE: ExAblate 2000/2100 Magnetic Resonance-guided Focused Ultrasound (MRgFUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Peripheral Mobilized Mononuclear Cell-based Therapy in Patient With Diabetic Neuropathy
Status: WITHDRAWN
Conditions: Diabetic Neuropathy
Interventions: BIOLOGICAL: Normal saline|BIOLOGICAL: stem-cell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intelligent Vacuum Assisted Biopsy Immediately Before Surgery as an Intra- or Pre-Operative Surrogate for Patient Response to Neoadjuvant Chemotherapy for Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: PROCEDURE: Vacuum assisted biopsy (VAB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Tolerance and Efficacy of a Predigested, High Protein, High Omega 3 Fat Enteral Feeding Formula Versus a Standard Formula In Multiple Intensive Care Unit Settings
Status: COMPLETED
Conditions: Critical Illness|Enteral Feeding
Interventions: OTHER: VITAL AF|OTHER: Osmolite 1.2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Secondary Prevention of Atrial Fibrillation (Impact of Renin-Angiotensin-Aldosterone System Inhibition)
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: OTHER: no drug|DRUG: start cozaar|DRUG: continue cozaar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vascular Boot Warming Program After Acute Deep Vein Thrombosis (DVT) ± Pulmonary Embolism (PE)
Status: TERMINATED
Conditions: Acute DVT of Lower Extremity
Interventions: COMBINATION_PRODUCT: Vascular Boot|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue
Status: COMPLETED
Conditions: Neoplasms of the Prostate
Interventions: DEVICE: AuroShell particle infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neurofeedback-enhanced Mindfulness Meditation in Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DEVICE: EEG neurofeedback-assisted meditation|DEVICE: Non-EEG feedback-assisted meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy With Camrelizumab in Locally Advanced Esophageal Squamous Cell
Status: UNKNOWN
Conditions: PFS
Interventions: DRUG: camrelizumab|DRUG: Paclitaxel|DRUG: Neoadjuvant Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP2408 Following Single Intravenous Doses in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP2408
Interventions: DRUG: ASP2408|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Non-Inferiority RCT Comparing Online and On-Site CBT in MDDi
Status: SUSPENDED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Standard psychiatry and cognitive behavioral online intervention|BEHAVIORAL: Standard psychiatry and cognitive behavioural in-person intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Alzheimer's Disease THErapy With NEuroaid (ATHENE) Study
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: DRUG: MLC901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the 12-month Spatz3 Adjustable Balloon With a 6-month Non Adjustable Balloon
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: DEVICE: Gastric Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Growth Factor Signature (GFS) Pilot Study (MK0000-098)(COMPLETED)
Status: TERMINATED
Conditions: Blast Phase Philadelphia Chromosomes Positive (Ph+) Chronic Myelogenous Leukemia (CML)|Philadelphia Chromosome Positive (Ph+) Acute Lymphocytic Leukemia (ALL)
Interventions: OTHER: Comparator: Biomarker evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: TLR-9 Antagonism in Steroid Resistant Optic Neuritis
Status: COMPLETED
Conditions: Optic Neuritis
Interventions: DRUG: Mycobacterium w.(Mw)-freeze dried extract 0.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic and Prognostic Accuracy of FDHT-PET and Liquid Biopsies in Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: FDHT-PET Scan|DIAGNOSTIC_TEST: liquid biopsies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessing Uterine Ultrasound Done as a Diagnostic Tool for the Depth of Carcinoma Invasion
Status: COMPLETED
Conditions: Endometrial Endometroid Carcinoma
Interventions: DEVICE: Intraoperative ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Better Understand Children and Adolescents' Intrafamilial Oppositional Defiant Disorder
Status: COMPLETED
Conditions: Oppositional Defiant Disorder With Familial Setting
Interventions: OTHER: Semi-directive interview (Kiddy Sads)|OTHER: SDQ questionnaires (strenghs and difficulties questionnaire)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Research for Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-MDS) in the Treatment of Myelodysplastic Syndrome (MDS)
Status: SUSPENDED
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Allogeneic umbilical cord mesenchymal stem cells|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Development & Evaluation of Pneumatic Artificial Muscle(PAM) for Patients With Ankle Foot Orthosis(AFO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthopedic Disorder
Interventions: DIAGNOSTIC_TEST: PneuFlex AFO Assist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cerebral Blood Flow and PETCO2 on Neuromuscular Function During Environmental Stress
Status: COMPLETED
Conditions: Healthy Males|Neuromuscular Function
Interventions: DRUG: Indomethacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Immunological Efficacy of the Pentavalent Rotavirus Vaccine - Rota-V-Aid™ (Live Attenuated Oral, Freeze-dried) at Healthy Adults Aged 18 to 45 Years.
Status: COMPLETED
Conditions: Rotavirus Infections|Rotavirus Vaccines
Interventions: BIOLOGICAL: The pentavalent rotavirus vaccine (live attenuated oral, freeze-dried)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cryosurgery and Radiation Therapy in Treating Patients With Painful Bone Metastases
Status: TERMINATED
Conditions: Bone Metastases|Pain
Interventions: PROCEDURE: cryosurgery|RADIATION: radiation therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety and Immunogenicity of Co-administration of the Candidate Influenza Vaccine MVA-NP+M1 and Seasonal Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: TIV and MVA-NP+M1|BIOLOGICAL: Saline placebo and seasonal influenza vaccine TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: CHF6523
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
Status: COMPLETED
Conditions: Healthy Person|Bowel Preparation Before Colonoscopy
Interventions: DRUG: 2L Coolprep®|DRUG: 1L Coolprep® and Bisacodyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Computed Tomography-Guided Catheter Ablation for Ventricular Tachycardia
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventricular Tachycardia
Interventions: DEVICE: image-guided VT ablation strategy|DEVICE: conventional VT ablation strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Opposite SI Joint Stretching for GIRD
Status: COMPLETED
Conditions: Shoulder Impingement
Interventions: PROCEDURE: Sleeper Stretch|PROCEDURE: Opposite SI joint Stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breakfast and Energy Expenditure in Young Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Control|DIETARY_SUPPLEMENT: Omega 3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC
Status: COMPLETED
Conditions: Contraception|HIV|Immune Cells (Mucosal and Systemic)|Microbiota
Interventions: DRUG: DMPA|DRUG: NET-EN|DRUG: MPA/E2|DEVICE: LNG-I|DEVICE: ENG-I|DEVICE: Cu-IUD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Pulmonary Rehabilitation Program on Post Hospitalization Severe COVID- 19 Patients
Status: COMPLETED
Conditions: Post COVID-19 Condition
Interventions: COMBINATION_PRODUCT: respiratory exercises - incentive spirometer - walking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Emergency Use of Adoptive Immunotherapy With CMV-Specific T Cells After Donor Bone Marrow Transplant of an Infant With Immunodeficiency Syndrome and CMV Infection
Status: NO_LONGER_AVAILABLE
Conditions: Infection|Precancerous/Nonmalignant Condition
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes|PROCEDURE: allogeneic bone marrow transplantation|RADIATION: total-body irradiation
Study Type: EXPANDED_ACCESS
Clinical trial: Sunitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
Interventions: DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Flexed Position in Percutanous Nephrolithotomy
Status: COMPLETED
Conditions: Renal Stones
Interventions: PROCEDURE: Percutanous nephrolithotomy (PCNL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Brilaroxazine (RP5063) in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Brilaroxazine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 70 vs 110 Degree Side-cut Angles in Femtosecond LASIK
Status: COMPLETED
Conditions: Operative Incision
Interventions: DEVICE: FS-LASIK 70 degree side-cut angle|DEVICE: FS-LASIK 110 degree side-cut angle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels
Status: RECRUITING
Conditions: Cervical Disc Herniation|Cervical Disc Degeneration|Degenerative Disc Disease
Interventions: DEVICE: Tritanium C Anterior Cervical Cage
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 4 Versus 6 Courses of Adjuvant Chemotherapy in LACC Patients Previously Treated With NACT Plus Radical Surgery
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: PROCEDURE: Group A adjuvant chemotherapy|PROCEDURE: Group B adjuvant chemotherapy|DRUG: Cisplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Medical Spastic Patient Machine Interface MSPMI : Biomechanical and Electrophysiological Assessment of the Triceps Surae Spasticity
Status: COMPLETED
Conditions: Spasticity, Muscle
Interventions: DEVICE: single assessment with the MSPMI|DEVICE: double assessment with the MSPMI with 7 days of interval|DEVICE: double assessment with the MSPMI before and after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nu-3 Gel for Infected Diabetic Foot Ulcers
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Infection
Interventions: DRUG: 5% Nu-3 gel|DRUG: 10% Nu-3 gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Virtual Reality Mask or Music Therapy for Analgesia and Anxiolytic Purpose When Totally IVAD for Chemotherapy Under Local Anesthesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Implanted Venous Access Device
Interventions: DEVICE: REV : local anesthesia and virtual reality|DEVICE: MUS : local anesthesia and music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dronabinol Naltrexone Treatment for Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: injectable naltrexone and dronabinol|DRUG: Naltrexone and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Enalapril and Losartan Association Therapy on Proteinuria and Inflammatory Biomarkers in Diabetic Nephropathy: a Clinical Trial on Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Macroalbuminuric Diabetic Nephropathy
Interventions: DRUG: enalapril|DRUG: losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Tolerability, Safety, Immunogenicity and Preventive Efficacy of the EpiVacCorona Vaccine for the Prevention of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: EpiVacCorona (EpiVacCorona vaccine based on peptide antigens for the prevention of COVID-19)|OTHER: Placebo (sodium chloride, a 0.9% solution for the preparation of dosage forms for injections)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Venous Thrombosis: Thrombus Removal With Adjunctive Catheter-Directed Thrombolysis
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Venous Thrombosis|Postphlebitic Syndrome|Venous Thromboembolism|Post Thrombotic Syndrome
Interventions: DRUG: Recombinant tissue plasminogen activator (rt-PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study With OHR/AVR118 in Advanced Cancer Patients With Anorexia-Cachexia
Status: UNKNOWN
Conditions: Anorexia|Cancer Cachexia
Interventions: DRUG: OHR/AVR118
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Mycotic Ulcer Treatment Trial II: A Randomized Trial Comparing Oral Voriconazole vs Placebo
Status: COMPLETED
Conditions: Corneal Ulcer|Eye Infections, Fungal
Interventions: DRUG: Voriconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SIM0718 in Adult and Adolescent Patients With Moderate to Severe Atopic Dermatitis
Status: NOT_YET_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: SIM0718 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Blood Stem Cell Collection and Transplant Procedures
Status: COMPLETED
Conditions: Myelodysplastic Syndrome (MDS)|Chronic Myelogenous Leukemia|Acute Lymphoblastic Leukemia|CML (Chronic Myelogenous Leukemia|CLL (Chronic Lymphocytic Leukemia)
Interventions: PROCEDURE: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Triple Therapy in Patients With Anti-MDA5 Antibody-positive Dermatomyositis
Status: RECRUITING
Conditions: Dermatomyositis, Adult Type|Interstitial Lung Disease
Interventions: DRUG: triple therapy|DRUG: dual-therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma|Diffuse Large B-Cell Lymphoma|Mantle Cell Lymphoma|Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Transformed Non-Hodgkin Lymphoma|Transformed Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Anti-CD19-CAR CMV-specific T-lymphocytes|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Multi-peptide CMV-Modified Vaccinia Ankara Vaccine|PROCEDURE: Myeloablative Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of CBT-i on CPAP Therapy Use and Drop Outs in OSAS Patients With Insomnia.
Status: UNKNOWN
Conditions: Insomnia|Obstructive Sleep Apnea|Cognitive Behavioral Therapy|Continuous Positive Airway Pressure
Interventions: BEHAVIORAL: Cognitive behavioural therapy for insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate Efficacy of Ursodeoxycholic Acid (UDCA) for the Prevention of Gallstone Formation After Gasterectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Patients who continued UDCA 300mg medication|OTHER: Patients who discontinued UDCA 300mg prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder
Status: RECRUITING
Conditions: Problems Related to Social Environment
Interventions: BEHAVIORAL: Clinic-Level Multidimensional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Switching From Oral Antipsychotics to Long-Acting Risperidone in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Risperidone prolonged release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Demonstrate the Effects of Pramlintide on Weight Reduction in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Diabetes|Weight Gain
Interventions: DRUG: Pramlintide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: Piromelatine 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Reliability of Demirjian Formula for Age Estimation Using Mandibular Third Molar in a Sample of Egyptian Population Using CBT: a Cross-sectional Study
Status: COMPLETED
Conditions: Estimated Age Calculated Based on Modified Demirjian Method Using Mandibular Left Third Molar
Interventions: OTHER: CBCT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS)
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome|Infertility
Interventions: DRUG: Menotropin|DRUG: Progesterone vaginal insert|DRUG: Follitropin beta|DRUG: Progesterone in oil|DRUG: leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dressing: Frequency of Change and Evaluation of an Antiseptic-Impregnated Catheter Dressing in ICU Patients
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome|Bacteremia
Interventions: DEVICE: Chlorhexidine Sponge (Biopatch TM)|BEHAVIORAL: 7-day catheter dressing frequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study FFR116364, a Placebo-controlled Study of GW685698X in Paediatric Subjects With Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Fluticasone furoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Feasibility of a Prevention m-Health App Intervention for Informal Caregivers of Outpatients
Status: COMPLETED
Conditions: Telemedicine|Caregivers|Pressure Ulcer
Interventions: DEVICE: mHealth App
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases
Status: UNKNOWN
Conditions: Brain Metastasis|Radiation Therapy Complication
Interventions: DRUG: TMZ|RADIATION: WBRT with avoidance of hippocampus|RADIATION: WBRT without avoidance of hippocampus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Visceral Manifold and Unitary Device Study for the Repair of Thoracoabdominal Aortic Aneurysms
Status: ACTIVE_NOT_RECRUITING
Conditions: Thoracoabdominal Aneurysms
Interventions: DEVICE: Visceral Manifold and Thoracic Bifurcation|DEVICE: Unitary Manifold
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Povidone-iodine vs Saline Solution in Colorectal Surgeries and Its Effects on the Surgical Site Infection
Status: RECRUITING
Conditions: Surgical Site Infection
Interventions: DRUG: Povidone-iodine|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Transcutaneous Electrical Acupoint Stimulation of P6 to Prevent Postoperation Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: Transcutaneous electrical acupoint stimulation|DEVICE: Sham transcutaneous electrical acupoint stimulation|DRUG: Tropisetron|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Spinal Anesthesia With Articaine and Bupivacaine for Outpatient Lower Limb Surgery
Status: COMPLETED
Conditions: Spinal Anesthesia
Interventions: DRUG: spinal administration of articaine|DRUG: spinal administration of bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Electromyographic (EMG) on the Anaesthesia Monitor
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Rocuronium bromide|DRUG: Rocuronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home Monitoring in Idiopathic Pulmonary Fibrosis; Improving Use of Anti-fibrotic Medication and Quality of Life
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: OTHER: Home monitoring program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Status: COMPLETED
Conditions: Ewing's Sarcoma|Osteosarcoma|Astrocytoma|Atypical Teratoid/Rhabdoid Tumor|Ependymoma|Germ Cell Tumor|Glioma|Medulloblastoma|Rhabdoid Tumor|Retinoblastoma|Clear Cell Sarcoma|Renal Cell Carcinoma|Wilms Tumor|Hepatoblastoma|Neuroblastoma|Rhabdomyosarcoma
Interventions: DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIBERTY 1: Efficacy & Safety Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
Status: COMPLETED
Conditions: Heavy Menstrual Bleeding|Uterine Fibroid
Interventions: DRUG: Relugolix|DRUG: Estradiol/norethindrone acetate|DRUG: Estradiol/norethindrone acetate placebo|DRUG: Relugolix placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacology Study of MT-3921 in Healthy Adult Males
Status: COMPLETED
Conditions: Healthy Adult Males
Interventions: BIOLOGICAL: MT-3921|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study Examining Exenatide Long-Acting Release in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: placebo|DRUG: placebo|DRUG: Exenatide LAR|DRUG: Exenatide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Darbepoetin in Contrast-induced Nephropathy
Status: TERMINATED
Conditions: Acute Kidney Injury
Interventions: DRUG: darbepoetin-α|DRUG: isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Childhood Alveolar Rhabdomyosarcoma|Childhood Botryoid-Type Embryonal Rhabdomyosarcoma|Childhood Embryonal Rhabdomyosarcoma|Localized Childhood Soft Tissue Sarcoma|Rhabdomyosarcoma|Sarcoma|Stage I Adult Soft Tissue Sarcoma AJCC v7|Stage II Adult Soft Tissue Sarcoma AJCC v7|Stage III Adult Soft Tissue Sarcoma AJCC v7
Interventions: DRUG: Cyclophosphamide|BIOLOGICAL: Dactinomycin|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Questionnaire Administration|RADIATION: Radiation Therapy|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lokomat Treadmill Training Effects on MS Gait
Status: COMPLETED
Conditions: Gait, Unsteady|Multiple Sclerosis
Interventions: OTHER: Body-weight supported treadmill training +/- Lokomat assistance|OTHER: Usual Care - no active intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites
Status: COMPLETED
Conditions: Ascites|Hepatic Cirrhosis
Interventions: DRUG: Tolvaptan|DRUG: Tolvaptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population
Status: COMPLETED
Conditions: Epilepsy|Mental Retardation|Developmental Disabilities
Interventions: BEHAVIORAL: Swallow instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
Status: COMPLETED
Conditions: Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Interventions: OTHER: Spinal Anesthesia with cerebral oxygen saturation monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: OSI-906|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity Behavioral Change Intervention in Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Lung Cancer|Sedentary Behavior|Fatigue
Interventions: BEHAVIORAL: Physical activity in the community|BEHAVIORAL: Conventional intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Menstrual Phase and Postoperative Pain
Status: COMPLETED
Conditions: Acute Postoperative Pain|Chronic Postoperative Pain
Interventions: OTHER: HAD scale|OTHER: The SF 12 test|OTHER: Visual analogue score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: ATG Plus PTCy vs ATG for CGVHD Prophylaxis
Status: RECRUITING
Conditions: Acute Leukemia|Myelodysplasia|Chronic Graft-versus-host-disease
Interventions: DRUG: Cyclophosphamide|DRUG: Anti-Thymocyte globulin (rabbit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Local Vaginal Estrogen in Postmenopausal Women With Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Vaginal Atrophy
Interventions: DRUG: Vaginal conjugated estrogen cream 0.5gm|DRUG: Vaginal conjugated estrogen cream 1.0gm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: DSP-0509|DRUG: DSP-0509, Pembrolizumab|DRUG: DSP-0509, Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Outreach Methods to Encourage Enrollment in Diabetes Prevention and Weight Management Programs
Status: COMPLETED
Conditions: PreDiabetes|Obesity
Interventions: OTHER: EHR gaps|OTHER: Bulk outreach|OTHER: Dietician call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: MUscle Side-Effects of Atorvastatin in Coronary Patients (MUSE) -Follow-up Study
Status: COMPLETED
Conditions: Statin Adverse Reaction
Interventions: DRUG: Atorvastatin mylan 40 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Outcome After Lichtenstein Operation vs. ProGrip Patch Repair of Inguinal Hernia
Status: COMPLETED
Conditions: Inguinal Hernia|Primary|Unilateral
Interventions: DEVICE: Open inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacodynamics, and Pharmacokinetics of Different Dosing Regimens of MK-8266 in Participants With Hypertension (MK-8266-008)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D|DRUG: Treatment E|DRUG: Treatment F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of MMFS-202-302 on Cognitive Enhancement in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: MMFS-202-302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-histamines Promote Electroacupuncture Analgesia: Basic and Clinical Research
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: electroacupuncture|DRUG: antihistamine(low dose) chlorpheniramine (Dexchlorpheniramine maleate)|DRUG: antihistamine(high dose) chlorpheniramine (Dexchlorpheniramine maleate)|DEVICE: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Repotrectinib and Osimertinib in NSCLC Patients
Status: RECRUITING
Conditions: Nsclc
Interventions: DRUG: Repotrectinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Docetaxel Plus Gemcitabine in Patients With Completely Resected Leiomyosarcoma (LMS) of the Uterus
Status: COMPLETED
Conditions: Uterine Leiomyosarcoma|Uterine Cancer
Interventions: DRUG: Docetaxel plus Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.
Status: WITHDRAWN
Conditions: Asthma|Asthma, Bronchial|Bronchial Asthma|Eosinophilia|Physiological Effects of Drugs
Interventions: DRUG: QAW039
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Education Given to the Patients Who Will Be Applied Coronary Angiography
Status: COMPLETED
Conditions: Coronary Angiography|Anxiety|Vital Signs|Education|Nursing|Nursing Care
Interventions: BEHAVIORAL: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Manual Therapy for Hand Osteoarthritis
Status: UNKNOWN
Conditions: Hand Osteoarthritis
Interventions: DEVICE: Neural mobilization|DEVICE: Gloreha device|DEVICE: Standardized exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bone Metabolic Activity in the Patellofemoral Joint in Patients With Unilateral PFP
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Anterior Knee Pain Syndrome
Interventions: OTHER: 18F NaF-PET/CT and cone beam CT scans
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Stress MRI to Evaluate Aortic Function (Compliance, Distensibility, Pulse Wave Velocity) and Left Ventricular Function : Validation in Healthy Volunteers and in Selected Patients. A Pilot Study.
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DEVICE: MRI|DEVICE: cardiac echography transthoracic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy in Treating Patients With Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: Bleomycin Sulfate (BLM)|BIOLOGICAL: Filgrastim (G-CSF)|BIOLOGICAL: Recombinant Interferon Alfa|DRUG: Carmustine|DRUG: Cisplatin (CDDP)|DRUG: Cyclophosphamide|DRUG: Cytarabine (ARA-C)|DRUG: Etoposide (VP-16)|DRUG: Idarubicin|DRUG: Ifosfamide|DRUG: Leucovorin Calcium|DRUG: Melphalan|DRUG: Methotrexate|DRUG: Methylprednisolone|DRUG: mitoxantrone hydrochloride (DHAD)|DRUG: Vincristine Sulfate|PROCEDURE: Peripheral Blood Stem Cell Transplantation|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveillance and Implementation of a Bundle of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat)
Status: RECRUITING
Conditions: Colon Rectal Cancer|Surgical Site Infection
Interventions: OTHER: Implementation of a bundle of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PEriToneal Catheter Versus Repeated Paracentesis for Ascites in Cirrhosis
Status: TERMINATED
Conditions: Cirrhosis|Ascites Hepatic|Ascites (Non-Malignant)
Interventions: DEVICE: PleurX, peritoneal tunnelated catheter|DEVICE: Large Volume Paracentesis|DRUG: Ciprofloxacin 500Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Phase Study to Assess Efficacy and Safety of AZD9567 Versus Prednisolone in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AZD9567|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Relative Dose Intensity of PARP Inhibitors in Real-life on a Population of Patients Over 70 Years With Advanced Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer
Interventions: OTHER: QoL surveys|OTHER: Geriatric assessment (G-CODE)|BIOLOGICAL: Blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Brain-Computer Interface-based Programme for the Treatment of ASD/ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorders
Interventions: OTHER: Intervention Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of MELT-100, IV Midazolam, and IV Ketamine
Status: COMPLETED
Conditions: Procedural Sedation
Interventions: DRUG: midazolam / ketamine sublingual tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Response in Blood and Tumor Tissue Samples From Patients With Unresectable Stage IV Squamous Cell Cancer of the Head and Neck Previously Treated With Cetuximab, Cisplatin, and Radiation Therapy
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|GENETIC: protein analysis|GENETIC: protein expression analysis|OTHER: enzyme-linked immunosorbent assay|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p