pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A School-based Prevention Intervention to Promote Wellbeing in Preadolescents
Status: COMPLETED
Conditions: Major Risk Factors for Noncommunicable Diseases
Interventions: OTHER: Diario della Salute (DDS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surufatinib Plus Anti-PD-1/L1 as Maintenance Therapy in Extensive-Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Extensive-Stage Small Cell Lung Cancer
Interventions: DRUG: Surufatinib|DRUG: Anti-PD-1/L1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Supplementation in Breastfed Newborn Infants
Status: WITHDRAWN
Conditions: Atopic Dermatitis|Food Allergies
Interventions: DRUG: B. infantis|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Remediation of Schizophrenia Sensory Gating Deficit With Aripiprazole
Status: UNKNOWN
Conditions: Schizophrenia|Sensory Gating
Interventions: DRUG: Aripiprzole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroids in the Maintenance of Remission of Proliferative Lupus Nephritis
Status: WITHDRAWN
Conditions: Lupus Nephritis
Interventions: DRUG: prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD)
Status: RECRUITING
Conditions: Post-traumatic Stress Disorder
Interventions: BEHAVIORAL: KopOpOuders-PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C|Thrombocytopenia
Interventions: DRUG: SB497115|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Zonisamide in Advanced Parkinson's Disease (PD) in Egyptian Population: Pilot Study
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Zonisamide Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Bupivacaine, Ketorolac, Ketamine, vs Bupivacaine Alone in Reducing Postoperative Pocket Pain
Status: NOT_YET_RECRUITING
Conditions: Pain Management
Interventions: DRUG: Bupivacaine alone OR Bupivacaine-Ketorolac-Ketamine (BKK) Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating a Laparoscopic Banded Sleeve Gastrectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Morbid Obesity
Interventions: DEVICE: Banded Sleeve Gastrectomy|DEVICE: Standard SG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Salty Life 7 Study: Effect of High Salt Intake on Several Physiological Systems in Immobilisation
Status: COMPLETED
Conditions: Bone Metabolism|Electrolyte Metabolism|Acid-Base Metabolism|Energy Metabolism|Circulation System
Interventions: OTHER: Dietary salt intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rituximab for the Treatment of Wegener's Granulomatosis and Microscopic Polyangiitis
Status: COMPLETED
Conditions: Vasculitis|Wegener's Granulomatosis|Microscopic Polyangiitis
Interventions: DRUG: Rituximab plus cyclophosphamide placebo (rituximab group)|DRUG: Cyclophosphamide plus rituximab placebo (control group)|DRUG: Azathioprine|DRUG: Methylprednisolone (or other glucocorticoid)|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Whether GSK239512 Can Remyelinate Lesions in Subjects With Relapsing Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: DRUG: GSK239512|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Mobility Interventions Using Smart Sensor Resources for Lower-Limb Prosthesis Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Amputation
Interventions: OTHER: Needs-based intervention (physical, psychological, or both)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing Water Exchange, Water Immersion and Air Insufflation Methods During Colonoscopy With the Option of on Demand Sedation
Status: COMPLETED
Conditions: Colon Neoplasm
Interventions: PROCEDURE: water immersion|PROCEDURE: water exchange|PROCEDURE: air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Evaluating Vitamin D in Allergic Bronchopulmonary Aspergillosis Complicating Asthma
Status: COMPLETED
Conditions: Allergic Bronchopulmonary Aspergilloses
Interventions: DRUG: Glucocorticoids|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Guided Bone Regeneration With and Without the Use of Intra-marrow Penetrations
Status: RECRUITING
Conditions: Ridge Augmentation
Interventions: PROCEDURE: Intra-marrow penetrations|PROCEDURE: No Intra-marrow penetrations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contrast The Role of Avitene And OK-432 in Reducing Seroma Formation After Axillary Lymphadenectomy for Breast Cancer
Status: UNKNOWN
Conditions: Drainage|Postoperative Complications
Interventions: DRUG: Avitene|DRUG: Sapylin|BEHAVIORAL: axillary drainage|OTHER: reexamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: GEN1042 Safety Trial and Anti-tumor Activity in Subjects With Malignant Solid Tumors
Status: RECRUITING
Conditions: Malignant Solid Tumor|Non Small Cell Lung Cancer (NSCLC)|Colorectal Cancer (CRC)|Melanoma|Head and Neck Squamous Cell Carcinoma (HNSCC)|Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: BIOLOGICAL: GEN1042|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: 5-FU|DRUG: Gemcitabine|DRUG: Nab paclitaxel|DRUG: Pemetrexed|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: PRM-151 (Zinpentraxin Alfa)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bupropion for ADHD in Adolescents With Substance Use Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Nicotine Dependence|Cannabis Use Disorder
Interventions: DRUG: Bupropion|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Conditioning Approach to Counter Loneliness in Adults
Status: NOT_YET_RECRUITING
Conditions: Loneliness
Interventions: BEHAVIORAL: Evaluative Conditioning with positive stimuli|BEHAVIORAL: Conditioning with neutral stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of the Treatment of Fungal Corneal Ulcers With Povidone-Iodine
Status: TERMINATED
Conditions: Fungal Keratitis
Interventions: DRUG: povidone-iodine 1.25% ophthalmic solution|DRUG: natamycin ophthalmic suspension, USP 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Tadalafil to Treat Erectile Dysfunction After Radiotherapy of Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Erectile Dysfunction
Interventions: DRUG: tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Resveratrol and Cardiovascular Health in the Elderly
Status: TERMINATED
Conditions: Vascular Resistance|Hypertension
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Antibiotics in the Treatment of Colonic Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Metronidazole placebo|DRUG: ciprofloxacin placebo|DRUG: ciprofloxacin|DRUG: metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternate Dosing of PROCRIT (Epoetin Alfa) in Patients With Cancer and Chemotherapy Induced Anemia
Status: COMPLETED
Conditions: Anemia|Chemotherapy
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial
Status: RECRUITING
Conditions: Crohn Disease
Interventions: OTHER: Whole-food based smoothie|OTHER: Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mode of Action of Ondansetron, a 5-HT Receptor 3 Antagonist, in Lactulose Induced Diarrhoea
Status: COMPLETED
Conditions: Motility Disorder of Intestine|Ondansetron|Small Bowel Water
Interventions: DRUG: Ondansetron 8mg|DIAGNOSTIC_TEST: abdominal MRI|DRUG: Lactulose|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intra-articular Corticosteroid Injections to Platelet Rich Plasma (PRP) for Cervical Facetogenic Pain
Status: COMPLETED
Conditions: Cervical Pain
Interventions: DRUG: Intraarticular platelet rich plasma cervical facet injection|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation Montelukast in the Treatment of Status Asthmaticus
Status: UNKNOWN
Conditions: Status Asthmaticus
Interventions: DRUG: Montelukast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Patients With Chronic Liver Diseases(Alcoholic Liver Disease and Non-Alcoholic Fatty Liver Disease), LAENNEC(Human Placenta Hydrolysate) is to Evaluate the Efficacy and Safety of Intravenous Drop
Status: NOT_YET_RECRUITING
Conditions: Chronic Liver Disease
Interventions: DRUG: LAENNEC (Human Placenta Hydrolysate) IV|DRUG: LAENNEC (Human Placenta Hydrolysate) SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of Clinical Course and Treatment Response in DBT Programmes
Status: RECRUITING
Conditions: Self Harm|Borderline Personality Disorder
Interventions: BEHAVIORAL: Dialectical Behaviour Therapy adapted for adolescents (DBT-A)|BEHAVIORAL: Dialectical Behaviour Therapy - Standard version (DBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GCSSG-SPNX: Trial to Evaluate Splenectomy in Total Gastrectomy for Proximal Gastric Carcinoma: JCOG0110
Status: COMPLETED
Conditions: Gastric Neoplasm
Interventions: PROCEDURE: Surgery: Splenectomy|PROCEDURE: Surgery: Spleen-preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Of PF-06439535 Plus Paclitaxel-Carboplatin And Bevacizumab Plus Paclitaxel-Carboplatin Patients With Advanced Non-Squamous NSCLC
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab-Pfizer|DRUG: Bevacizumab-EU|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fat Metabolism in Response to Acute Diet- and Exercise-induced Changes in Energy Balance
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Positive energy balance|BEHAVIORAL: Energy balance with exercise|BEHAVIORAL: Negative energy balance|BEHAVIORAL: Negative energy balance with exercise|BEHAVIORAL: Energy balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Preladenant for the Treatment of Antipsychotic Induced Movement Disorders in Participants With Schizophrenia (Study P04628)
Status: TERMINATED
Conditions: Akathisia, Drug-Induced|Dyskinesia, Drug-Induced|Parkinsonian Disorders
Interventions: DRUG: Preladenant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glargine Insulin vs.Continuous Regular Insulin in Diabetic Surgical Patients Receiving Parenteral Nutrition (GLUCOSE-in-PN)
Status: COMPLETED
Conditions: Diabetic Patients With Gastrointestinal Cancer Undergoing Surgery and Receiving Parenteral Nutrition
Interventions: DRUG: Glargine Insulin|DRUG: Regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alcohol Brief Intervention Plus Personalized Mobile Chat-based Intervention to Reduce Alcohol Misuse in an Emergency Department
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Mobile chat-based instant messages|BEHAVIORAL: Alcohol brief intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Confirmation Trial of CDP870 as add-on Medication to Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CDP870 400mg|DRUG: CDP870 200mg|DRUG: CDP870 100mg|DRUG: Placebo of CDP870
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assert-IQ Implantable Cardiac Monitor (ICM) Post Market Study
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal|Atrial Fibrillation, Persistent|Cardiac Arrhythmia|Ablation
Interventions: DEVICE: Holter monitoring in patients who have been successfully implanted with an Abbott Assert-IQ ICM device
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery
Status: COMPLETED
Conditions: Hemodynamics, Liver, Terlipressin
Interventions: DRUG: terlipressin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Partly-blinded Investigation to Evaluate the Clinical Performance and Safety of pHyph in Adult Women With Bacterial Vaginosis Compared With an Untreated Control Group
Status: ACTIVE_NOT_RECRUITING
Conditions: Bacterial Vaginosis
Interventions: DEVICE: pHyph
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing KIM to TVT Exact Sling
Status: COMPLETED
Conditions: Stress Urinary Incontinence
Interventions: DEVICE: Gynecare TVT Exact Continence System|DEVICE: Neomedic KIM (Knotless Incontinence Mesh)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Children 2 to <18 Years of Age at High Risk of Respiratory Syncytial Virus
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: mRNA-1345|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotics for Prevention of Antibiotic-associated Diarrhea
Status: COMPLETED
Conditions: Antibiotic-Associated Diarrhea
Interventions: OTHER: Jarro-Dophilus EPS probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Complete Decongestive Therapy With Intermittent Pneumatic Compression for Treatment of Lipedema
Status: COMPLETED
Conditions: Lipedema
Interventions: COMBINATION_PRODUCT: Combined decongestive treatment (CDT) & Combined exercise|COMBINATION_PRODUCT: Intermittent pneumatic compression & Combined exercise|COMBINATION_PRODUCT: Combined exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LC15-0444|DRUG: Metformin|DRUG: LC15-0444+Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Contrast on Platelet Activity, Thrombosis and Fibrinolysis in Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Iodixanol|DRUG: Ioxaglate|DRUG: Bivalirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Procalcitonin Versus C-reactive Protein to Guide Therapy in Community Acquired Pneumonia
Status: WITHDRAWN
Conditions: Community-acquired Pneumonia
Interventions: OTHER: CRP|OTHER: PCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of Participants With Relapsing-Remitting Multiple Sclerosis (RRMS)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: LY2127399|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The EC50 of Remifentanil Blunting Hemodynamic Response to Double Lumen Tube Intubation
Status: COMPLETED
Conditions: Hemodynamic Responses During Tracheal Intubation
Interventions: DRUG: Remifentanil|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of ART6043 in Advanced/Metastatic Solid Tumors Patients
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: ART6043|DRUG: Olaparib|DRUG: Niraparib|DRUG: Olaparib|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of GSK1322322 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers
Status: WITHDRAWN
Conditions: Infections, Bacterial
Interventions: DRUG: GSK1322322 1200 mg|DRUG: GSK1322322 3000 mg|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Integrated Care Combined Nutrition and Lifestyle Counselling in Frail Older Patients With Diabetes
Status: RECRUITING
Conditions: Frailty|Diabetes|Lifestyle
Interventions: BEHAVIORAL: Integrated care with nutrition and lifestyle counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Label Study of the Effects of Secukinumab on Nail Psoriasis and Non-Invasive Measures of Enthesitis (Phase IV)
Status: RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Secukinumab Auto-Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microsurgical Versus Conventional Semilunar Coronally Advanced Flap
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: MICROSURGERY|PROCEDURE: MACROSURGERY|DRUG: Dexamethasone|DRUG: Chlorhexidine gluconate|DRUG: 2.0% Mepivacaine + 1:100.000 epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Med-South Lifestyle Program for Pregnancy
Status: NOT_YET_RECRUITING
Conditions: Pregnancy Complications
Interventions: BEHAVIORAL: Med-South Lifestyle Intervention for Pregnancy--Arm 1|BEHAVIORAL: Med-South Lifestyle Intervention for Pregnancy--Arm 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer
Status: UNKNOWN
Conditions: Anastomotic Leak|Anastomotic Haemorrhage|Anastomotic Complication|Rectal Neoplasms|Staple Misfire|Anastomosis|Anastomotic Stenosis
Interventions: DEVICE: Three-row circular stapler|DEVICE: Two-row circular stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Nonoperative Management (NOM)|PROCEDURE: Local Excision (LE)|PROCEDURE: Total Mesorectal Excision (TME)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy
Status: UNKNOWN
Conditions: Brain Tumors
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ilofotase Alfa for Prevention of Renal Damage After Cardiac Surgery
Status: RECRUITING
Conditions: Open Heart Surgery
Interventions: DRUG: Ilofotase alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Double Bundle ACL Reconstructions, in Term of Cartilage Damage Due to Remaining Instability After Surgery.
Status: UNKNOWN
Conditions: Anterior Cruciate Ligament Rupture|Knee Instability|Cartilage Damage
Interventions: PROCEDURE: Single Bundle ACL Reconstruction|PROCEDURE: Double Bundle ACL Reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy
Status: RECRUITING
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss
Status: TERMINATED
Conditions: Bone Demineralization
Interventions: DRUG: Alendronate|DRUG: Placebo|DIETARY_SUPPLEMENT: calcium carbonate and colecalciferol|DRUG: Tenofovir disoproxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise for Young Adults With Cancer
Status: COMPLETED
Conditions: Fatigue|Cancer|Physical Activity|Exercise
Interventions: BEHAVIORAL: Exercise - Social Media|BEHAVIORAL: Exercise - App|BEHAVIORAL: Exercise - closed to patients residence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NMR-based Metabolic Profiling Identifies High Risk of MAFLD Patients With Advanced Fibrosis
Status: NOT_YET_RECRUITING
Conditions: Metabolic Dysfunction-associated Fatty Liver Disease|Metabolic Disease
Interventions: DEVICE: NMR-based metabolic profiling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Osteopathy in Chronic Obstructive Pulmonary Disease (COPD) Rehabilitation Trial
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Active osteopathic treatment (OMT+PR): Active Comparator|OTHER: sham osteopathic treatment (SOT+PR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Virtual Reality Distraction During Arteriovenous Fistula Puncture
Status: COMPLETED
Conditions: Pain Management|Hemodialysis|Virtual Reality
Interventions: PROCEDURE: virtual reality distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Malposition Rates of the Vertebral Pedicle Screws Using the PediGuard Technique: PediGuard Technique Associated With Fluoroscopy and Fluoroscopy Alone
Status: COMPLETED
Conditions: Pedicular Screwing
Interventions: DEVICE: Pediguard|OTHER: Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dermacyd PH_DESILSTY_FL (Lactic Acid) - Acceptability - Stay on Floral.
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: LACTIC ACID(ND)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topical Umeclidinium in Primary Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: Umeclidinium|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conversational Agents to Improve HPV Vaccine Acceptance in Primary Care (ECA-HPV) Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Human Papilloma Virus
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: ECA-HPV App with Clinic Notification and Adolescent Functions Disabled|BEHAVIORAL: ECA-HPV App with Clinic Notification Function Enabled|BEHAVIORAL: ECA-HPV App with Adolescent Function Enabled|BEHAVIORAL: ECA-HPV App with Clinic Notification and Adolescent Functions Enabled
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: LCS Complete Duofix|DEVICE: LCS Complete Porocoat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eplerenone Treatment for Chronic Central Serous Chorioretinopathy in Hungarian Population
Status: COMPLETED
Conditions: Chronic Central Serous Chorioretinopathy
Interventions: DRUG: Inspra (eplerenone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate GLPG0634 in Subjects With Renal Impairment Compared to Healthy Subjects
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: GLPG0634
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variation of COMT Val158Met Polymorphism Between COM-ON Patients and METHADOSE Patients
Status: COMPLETED
Conditions: Opioid-related Disorders|Opiate Dependence|Opiate Addiction|Opiate Abuse
Interventions: GENETIC: COMT polymorphism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess 7/8 HLA-matched Hematopoietic Stem Cell Transplantation Participants Treated With or Without Abatacept in Combination With a Calcineurin Inhibitor and Methotrexate
Status: COMPLETED
Conditions: Stem Cell Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of an Inhaled Corticosteroid on Airway Gene Expression in Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Inhaled fluticasone 500 ug BID for 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Weightbearing Restrictions on Postoperative Outcomes Following Arthroscopic Surgery for FAI
Status: RECRUITING
Conditions: Femoro Acetabular Impingement
Interventions: OTHER: Weight-bearing As Tolerated|OTHER: Partial Weight-bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Intervention to Improve Lifestyles in Subjects With Intermediate Cardiovascular Risk.
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Individual counselling on lifestyles|BEHAVIORAL: Additional group counselling on lifestyles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Ability of Osteopathic Structural Evaluation to Assess Gait
Status: COMPLETED
Conditions: Osteopathic Manipulation|Postural; Defect|Somatic; Functional Disturbance
Interventions: PROCEDURE: Osteopathic Manipulative Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of SYM-SV/DS-002 in Patients With Severe Aortic Stenosis
Status: TERMINATED
Conditions: Severe Aortic Stenosis
Interventions: DEVICE: SYM-SV-002 Aortic Bioprosthesis and SYM-DS-002 Transfemoral Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Dermal Cells Into the Balding Scalp of Subjects With Hair Loss
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Short-term Mixed Exercise for Sarcopenic Hospitalized Aged 80+ Years
Status: COMPLETED
Conditions: Sarcopenia
Interventions: BEHAVIORAL: balance training|BEHAVIORAL: resistance training|BEHAVIORAL: aerobic exercise|BEHAVIORAL: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Corticospinal Excitability After rTMS in Spinal Cord Injury Patients
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DEVICE: High frequency rTMS (repetitive Transcranial Magnetic Stimulation)|DEVICE: Low frequency rTMS (repetitive Transcranial Magnetic Stimulation)|DEVICE: sham rTMS (repetitive Transcranial Magnetic Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve
Status: RECRUITING
Conditions: Fertility Issues
Interventions: OTHER: Blood sample taking , like to measure hormonal level like LH, FSH, Perlakan ,in a follicular fluid after the oocyte retrival
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effectiveness of Neurodynamic Techniques in Patients With Nerve-Related Leg Pain
Status: COMPLETED
Conditions: Nerve Pain|Peripheral Nerve Injuries|Peripheral Nervous System Diseases|Sciatica|Low Back Pain|Low Back Ache|Signs and Symptoms
Interventions: PROCEDURE: Neurodynamic Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Central Hypersensitivity in Chronic Musculoskeletal Pain by Intravenous Tropisetron
Status: COMPLETED
Conditions: Pain|Chronic Disease
Interventions: DRUG: Tropisetron 2 mg|DRUG: Tropisetron 5mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Optimal Time of Methimazole Discontinuation Before Radio-iodine Therapy in Hyperthyroid Grave's Patients
Status: COMPLETED
Conditions: Graves Disease
Interventions: DRUG: Methimazole|DRUG: Methimazole|DRUG: Methimazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T Cells Expressing a Bispecific CAR Targeting CS1 and BCMA in Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: CS1+ or BCMA+ Multiple Myeloma
Interventions: BIOLOGICAL: Conditioning chemotherapy followed by CAR T cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-centre Prospective Cohort of Childhood Leukaemia: Determinants of Health and Quality of Life of the Patients After Treatment for an Acute Leukaemia During Childhood or Adolescence - LEA
Status: UNKNOWN
Conditions: Leukaemia During Childhood or Adolescence
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interfaces of Non-invasive Ventilation on Performance in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Non Invasive Ventilation|Exercise, Aerobic
Interventions: DEVICE: Non invasive ventilation during exercise with facial or nasal mask.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Pharmacist Intervention on Capecitabine Relative Dose Intensity, Adherence, Knowledge & Safety Among Cancer Patients in Malaysia
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: OTHER: Pharmacist-led Oral Chemo Care Program (POCCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Utidelone Versus Docetaxel in HER2-negative Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms|Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: utidelone|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lactobacillus Paracasei PS23 for Patients With Post-COVID-19 Syndrome
Status: TERMINATED
Conditions: Post-COVID-19 Syndrome
Interventions: DIETARY_SUPPLEMENT: PS23 heat-treated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of a Dietary Fibre Supplementation of a Low Calorie Diet on Appetite and Body Weight
Status: COMPLETED
Conditions: Appetite Suppression|Weight Loss
Interventions: DIETARY_SUPPLEMENT: PolyGlycopleX (PGX)|DIETARY_SUPPLEMENT: Rice flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of A Combination Pill With GS-7977 and GS-5885 for Hepatitis C in People With HIV
Status: COMPLETED
Conditions: Hepatitis C|HIV
Interventions: DRUG: GS-7977/GS- 5885 FDC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AGN-242428 in the Treatment of Plaque Psoriasis
Status: TERMINATED
Conditions: Plaque Psoriasis
Interventions: DRUG: AGN-242428|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigation Into the Mechanism of Inhalation Cough Challenge
Status: COMPLETED
Conditions: Cough
Interventions: OTHER: Nebulised citric acid in serial dilutions|OTHER: Nebulised ATP solution in serial dilutions|OTHER: Nebulised TRPA1 agonist solution in serial dilutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate Vaccine Against Chickenpox and a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and Chickenpox
Status: COMPLETED
Conditions: Varicella|Chickenpox Vaccines
Interventions: BIOLOGICAL: Priorix-tetra™|BIOLOGICAL: Priorix™|BIOLOGICAL: Varilrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy, and Pharmacokinetic Behavior of Leuprolide Mesylate (LMIS 25 mg) in Subjects With Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Leuprolide Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma Multiforme|Glioblastoma Multiforme of Brain|Astrocytoma, Grade IV|Brain Tumor|Brain Cancer|Brain Neoplasms
Interventions: PROCEDURE: Awake craniotomy|PROCEDURE: Craniotomy under general anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Denture Adhesive is a Patient Advantageous or Prosthetic Failure During Adaption Period: Randomized Control
Status: COMPLETED
Conditions: Dental
Interventions: OTHER: denture adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia
Status: RECRUITING
Conditions: Presbyopia|Near Vision|Miosis|Eye Diseases
Interventions: DRUG: Aceclidine+Brimonidine combination ophthalmic solution|DRUG: Aceclidine ophthalmic solution|DRUG: Placebo (Vehicle) ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria
Status: COMPLETED
Conditions: Diabetic Kidney Disease
Interventions: DRUG: TMX-049|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Palifermin After Haploidentical PBSCT
Status: WITHDRAWN
Conditions: Non-Hodgkin's Lymphoma or Hodgkin's Disease|Acute Leukaemia|Myelodysplastic Syndrome|Chronic Myeloid Leukemia|Osteomyelofibrosis
Interventions: DRUG: Palifermin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sugammadex v.s. Neostigmine/Glycopyrrolate
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Neoplasms|Chronic Sinusitis|Chronic Otitis Media
Interventions: DRUG: Group S: sugammadex injection|DRUG: Group N: neostigmine/glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of an Edible Algal Extract (Ulva Lactuca) on the Component of Depression in Healthy Volunteers With Anhedonia
Status: COMPLETED
Conditions: Anhedonia in Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Ulva Lactuca|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Understand Novel Biomarkers in Researching Dementia
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer Disease|Mild Cognitive Impairment|Dementia
Interventions: DIAGNOSTIC_TEST: Clinical tau PET|DIAGNOSTIC_TEST: Clinical amyloid test|OTHER: Research blood collection|OTHER: Cognitive assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Dermatitis, Atopic
Interventions: DRUG: GSK1070806|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Placental Drainage of Fetal Blood at Cesarean Section on the Incidence of Feto-Maternal Transfusion
Status: COMPLETED
Conditions: Fetomaternal Transfusion
Interventions: PROCEDURE: drainage of placenta of fetal blood
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Abdominal Exercises and Kinesio Taping on Abdominal Strength in Females With Diastasis Recti.
Status: COMPLETED
Conditions: Diastasis Recti|Kinesio Taping
Interventions: OTHER: Kinesio taping|OTHER: Abominal exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: HMB Enriched Amino Acids to Reverse Muscle Loss in Cirrhosis
Status: RECRUITING
Conditions: Cirrhosis, Liver
Interventions: DIETARY_SUPPLEMENT: Hydroxy Methyl Butyrate|DIETARY_SUPPLEMENT: Balanced Amino Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of a Diabetes Vaccine in Newly Diagnosed Diabetics
Status: COMPLETED
Conditions: Insulin-dependent Diabetes Mellitus|Diabetes Mellitus
Interventions: BIOLOGICAL: IBC-VS01|BIOLOGICAL: IBC-VS01 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between Telaprevir and Buprenorphine
Status: COMPLETED
Conditions: Hepatitis C|Opioid-Related Disorders
Interventions: DRUG: telaprevir|DRUG: buprenorphine/naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Modified 2.2mm Microincision Phacoemulsification for Age-related Cataract
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: modified 2.2mm microincision|PROCEDURE: conventional 2.2mm microincision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION