pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prosthetic Rehabilitation of Lip and Palate Deformaties in Neonates Using Two Different Approaches
Status: COMPLETED
Conditions: Evaluation
Interventions: DEVICE: nasoalveolar molding appliance|DEVICE: digital nasoalveolar molding appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of Triostat in Infants During Heart Surgery
Status: COMPLETED
Conditions: Heart Defects, Congenital
Interventions: DRUG: Liothyronine sodium/triiodothyronine|PROCEDURE: Cardiopulmonary bypass and cardiac surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Spinal Anesthesia Compared With Traditional Epidural Anesthesia Concerning Peroperative and Postoperative Pain After Open Nephrectomy in Patients With Renal Cell Carcinoma
Status: COMPLETED
Conditions: Pre- and Postoperative Analgesia|Spinal Anesthesia|Renal Cell Carcinoma
Interventions: DRUG: klonidin|DRUG: epidural anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbial Transplants for the Treatment of Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Fecal Microbiota Transplantation|DRUG: Fecal Microbiota Transplantation Capsule|OTHER: Questionnaire Administration|PROCEDURE: Resection|PROCEDURE: Therapeutic Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Long-Term Safety and Efficacy of SPN-812 (Viloxazine Extended-release Capsule) in Adults With ADHD
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder
Interventions: DRUG: SPN-812
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Application of the Self Care Deficit Nursing Theory in Adolescents With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Adolescence|Self-care
Interventions: OTHER: Supportive-Educative Nursing Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Sugammadex (Org 25969) With Neostigmine as Reversal Agents for Rocuronium or Vecuronium at Reappearance of T2 (P05960)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex|DRUG: Neostigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors
Status: COMPLETED
Conditions: Advanced Nonhaematologic Malignancies
Interventions: DRUG: BOS172738
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dan-NICAD - Danish Study of Non-Invasive Diagnostic Testing in Coronary Artery Disease
Status: COMPLETED
Conditions: Angina Pectoris|Arteriosclerosis|Coronary Artery Disease|Myocardial Ischemia
Interventions: PROCEDURE: SPECT|PROCEDURE: Cardiac MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Carbetocin Versus Buccal Misoprostol Plus IV Tranexamic Acid for Prevention of Postpartum Hemorrhage at Cesarean Section
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: DRUG: carbetocin|DRUG: Tranexamic Acid|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Waterless Hand Cleansing With Chlorhexidine During the Perinatal Period
Status: COMPLETED
Conditions: Hand Washing Behavior|Hand Cleansing Behavior|Chlorhexidine|Neonatal Period
Interventions: BEHAVIORAL: Hand cleansing with chlorhexidine|BEHAVIORAL: Mother and neonatal health counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Matrices on Serum Fructose.
Status: ACTIVE_NOT_RECRUITING
Conditions: Fructose Metabolism Disorder
Interventions: OTHER: Apple|OTHER: Mashed apple|OTHER: Apple juice|OTHER: Fructose powder in water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect Of Health Extension Worker-Led Based Interventions on Improving Self-Management Behavior Among Diabetic Patients in Ethiopia
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Self-management Behavior and Glycosylated Hemoglobin Levels
Interventions: BEHAVIORAL: Health Extension Led club based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Misoprostol Prior to IUD Insertion in Nullipara
Status: COMPLETED
Conditions: Family Planning
Interventions: DRUG: Vaginal misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation
Status: NOT_YET_RECRUITING
Conditions: Spinal Fusion|Spinal Deformity|Spine Injury
Interventions: DEVICE: O-ARM (Medtronic, Inc, Louisville, CO)|PROCEDURE: Conventional corrective surgery for arthrodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of PBI-4050 and Its Effects on the Biomarkers in Subjects With Alström Syndrome
Status: COMPLETED
Conditions: Inflammation and Fibrosis|Diabetes
Interventions: DRUG: PBI-4050
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Tacrolimus|DRUG: Sirolimus|DRUG: Any prophylaxis for GVHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil
Status: TERMINATED
Conditions: Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|DRUG: methylprednisolone|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Mosunetuzumab + Lenalidomide|DRUG: - Rituximab + Lenalidomide (28-days cycles|DRUG: - Rituximab + Bendamustine (28-days cycles)|DRUG: - Rituximab + CHOP (21-days cycles)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Information Assistance Application in Addition to a Traditional Anesthesia Consultation on Preoperative Anxiety in Pediatrics: Prospective Randomized Trial
Status: UNKNOWN
Conditions: Pediatric Surgery
Interventions: OTHER: additional information via the computerized tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Motor-cognitive Training Effects on Cognition in Breast Cancer Survivors: the BRAINonFIT Study (BRAINonFIT).
Status: RECRUITING
Conditions: Breast Cancer Survivors|Cognitive Impairment|Executive Dysfunction
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Motor-cognitive Training|BEHAVIORAL: Health and Wellness
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mind Nutrition Study: Nutrition in the Prevention of Depressiveness and Sustaining Work Ability
Status: NOT_YET_RECRUITING
Conditions: Depressive Symptoms|Nutrition, Healthy|Quality of Life|Eating Behavior|Work-Related Condition
Interventions: BEHAVIORAL: Mind Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion
Status: COMPLETED
Conditions: Cervical Degenerative Disc Disease|Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: BIOLOGICAL: NeoFuse|DEVICE: MasterGraft Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Evixapodlin (Formerly GS-4224) in Participants With Advanced Solid Tumors
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Evixapodlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RANKL Inhibition and Breast Tissue Biomarkers
Status: COMPLETED
Conditions: Breast Cancer Prevention|Mammographic Density
Interventions: PROCEDURE: Ultrasound-guided core needle biopsy|DRUG: Denosumab|PROCEDURE: Blood draw|DRUG: Calcium|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality and Computerized Cognitive Intervention for Mild Cognitive Impairment in Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Vita|BEHAVIORAL: Com|BEHAVIORAL: Vita+Com
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tomographic Comparison of Aerosol Lung Distribution With Two Nebulizers Through a High Flow Nasal Cannula
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Technetium-99m - Diethylenetriaminepentaacetic acid|DEVICE: Aeroneb Solo|DEVICE: Jet Nebulizer|OTHER: Single photon emission computed tomography|OTHER: Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study of Rasburicase as Treatment or Prevention of Hyperuricemia Associated With Tumor Lysis Syndrome in Patients With Relapsed or Refractory Lymphoma, Leukemia, or Solid Tumor Malignancy
Status: COMPLETED
Conditions: Tumors|Hyperuricemia|Tumor Lysis Syndrome
Interventions: DRUG: Rasburicase (SR29142)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer
Status: TERMINATED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Adrenal Insufficiency
Interventions: DRUG: Prednisolone|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioactive Glass Air-abrasion and Non-carious Cervical Lesions
Status: COMPLETED
Conditions: Cervical Lesion
Interventions: PROCEDURE: Air-abrasion|PROCEDURE: Adhesive application - Etch&rinse|BIOLOGICAL: Adhesive application - Self-etch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With Induction
Status: COMPLETED
Conditions: Induced; Birth
Interventions: DRUG: Continuation or discontinuation of oxytocin during the active first stage of labor (≥6 cm dilation).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy and Temozolomide Followed by Temozolomide Plus Sorafenib for Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: RADIATION: Radiation Therapy|DRUG: Temozolomide|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enterade in Carcinoid/Non-Carcinoid Syndrome Neuroendocrine Tumor Patients With Quality of Life Limiting Bowel Frequency
Status: TERMINATED
Conditions: Neuroendocrine Tumor|Carcinoid Syndrome
Interventions: DIETARY_SUPPLEMENT: Enterade®|OTHER: Functional Assessment of Chronic Illness Therapy for Patients with Diarrhea (version 4.0)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Green Tea Extract on Obese Women With High Level of LDL
Status: COMPLETED
Conditions: Obese|Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: green tea extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short Versus Long-term Androgen Deprivation Therapy With Salvage Radiotherapy in Prostate Cancer. URONCOR 0624
Status: RECRUITING
Conditions: Prostate Cancer|Salvage Radiotherapy|Biochemical Recurrence|Androgen Deprivation Therapy|Metastases-free Survival
Interventions: DRUG: triptorelin, goserelin, leuprorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aortic Valve Replacement Above the Aortic Annulus (SA-AVR) With the Carpentier-Edwards Magna-Ease Bioprosthesis
Status: COMPLETED
Conditions: Aortic Valve Disease|Prosthesis; Cardiac, Heart, Functional Disturbance as Result
Interventions: PROCEDURE: aortic valve replacement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Effect of VIA-2291 on Atherosclerotic Vascular Inflammation in Patients Undergoing Elective Carotid Endarterectomy
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: VIA-2291|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolic Impact Assessment of Tenofovir Disoproxil Fumarate on Non-HIV-1 Infected Healthy Adult Male Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir Disoproxil Fumarate|DRUG: Tenofovir DF placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Umbilical Cord Mesenchymal Stem Cells Combined With Collagen Scaffold in the Treatment of Thin Endometrium
Status: COMPLETED
Conditions: Thin Endometrium|Intrauterine Adhesion
Interventions: DRUG: umbilical cord mesenchymal stem cells combined with collagen scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of 18 to 24mg/Day Ropinirole Controlled Release (CR) Tablets in Early and Advanced Parkinson's Disease (PD) Patients.
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: DRUG: Ropinirole CR 2mg tablet|DRUG: Ropinirole CR 8mg tablet|DRUG: Ropinirole CR matching Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: atovaquone/proguanil 250mg/100mg (A/P)|BIOLOGICAL: PfSPZ Challenge (NF54)|OTHER: NaCl 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Different Immunization Strategies in Zhejiang Province
Status: UNKNOWN
Conditions: Japanese Encephalitis|Vaccine Preventable Disease|Vaccine Reaction
Interventions: BIOLOGICAL: Japanese Encephalitis Vaccine (Vero Cell), Inactivated;|OTHER: No prospective interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Therapy to Prevent Sexual Pain in Breast Cancer Survivors
Status: COMPLETED
Conditions: Vulvodynia|Dyspareunia|Breast Cancer|Menopause
Interventions: DRUG: Topical liquid lidocaine|DRUG: Topical saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1029 in Participants With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: MK-1029|DRUG: Placebo for MK-1029
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High Dose Parenteral Ascorbic Acid On Microcirculation In Sepsis
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DRUG: Ascorbic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study ：SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Negative
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Receptor Positive,Human Epidermal Receptor 2 Negative, Node-positive, High Risk, Early Stage，Female Breast Cancer
Interventions: DRUG: SHR6390|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase IIa Study Investigating the Tolerance, Efficacy and Safety of HSK3486
Status: COMPLETED
Conditions: Induction of General Anaesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Udenafil Therapy in Patients With Heart Failure With Preserved Ejection Fraction [ULTIMATE-HFpEF]
Status: UNKNOWN
Conditions: Diastolic Heart Failure
Interventions: DRUG: Placebo|DRUG: Udenafil (Zydena)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partial Rebreathing in the Treatment of Migraine With Aura
Status: COMPLETED
Conditions: Migraine With Aura
Interventions: DEVICE: Active partial rebreathing device|DEVICE: Dummy partial rebreathing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Chronic Pain|Acute Pain|Depression, Anxiety
Interventions: OTHER: Questionnaires|OTHER: Mechanical Temporal Summation assessment|OTHER: Pain threshold assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment and Rehabilitation of Patients With Hip Arthroplasty to Regain Walk and Work Efficiency and Quality of Life
Status: COMPLETED
Conditions: Osteoarthritis, Hip
Interventions: BEHAVIORAL: Maximal strength training|BEHAVIORAL: conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alpha-2a and Ribavirin to Treat Hepatitis C in HIV-infected Patients
Status: COMPLETED
Conditions: Hepatitis C|HIV Infections
Interventions: DRUG: Double dose pegylated interferon with weight based Ribavirin|DRUG: standard dose pegylated interferon alfa -2a and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative 13N-Ammonia Cardiac Rest/Stress Digital PET/CT
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Cardiac Perfusion Rest/Stress Digital PET/CT|DRUG: N-13 ammonia|DRUG: Regadenoson
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study of GC33 in Advanced or Metastatic Liver Cancer (Hepatocellular Carcinoma)
Status: COMPLETED
Conditions: Advanced or Metastatic HCC
Interventions: DRUG: GC33
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Recombinant FVIII in Healthy Male Subjects Treated With TB-402
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Administration of recombinant FVIII/placebo in healthy male subjects treated with TB-402
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Dose-response Study With Subcutaneous Immunotherapy of an Standardized Dermatophagoides Pteronyssinus (DPT) Extract
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Allergovac depot|BIOLOGICAL: Allergovac depot|BIOLOGICAL: Allergovac depot|BIOLOGICAL: Allergovac depot|BIOLOGICAL: Allergovac depot|BIOLOGICAL: Allergovac depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Relative Bioavailability of Tablet Formulations of GSK2248761 in Healthy Adult Subjects. SGN114435
Status: COMPLETED
Conditions: Infections, Human Immunodeficiency Virus and Herpesviridae|Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK2248761 WBM Capsule|DRUG: GSK2248761 WBM Tablet Formulation 1|DRUG: GSK2248761 WBM Tablet Formulation 2|DRUG: GSK2248761 WBM Tablet Formulation 3|DRUG: GSK2248761 WBM Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of a Range of Naltrexone Doses in Combination With Smoked Marijuana
Status: COMPLETED
Conditions: Marijuana Use
Interventions: DRUG: Placebo + Inactive Marijuana (0% THC)|DRUG: Placebo + Active Marijuana (3.27% THC)|DRUG: Naltrexone 12 Mg+ Active Marijuana (3.27% THC)|DRUG: Naltrexone 25 Mg + Active Marijuana (3.27% THC)|DRUG: Naltrexone 50 Mg+ Active Marijuana (3.27% THC)|DRUG: Naltrexone 100 Mg+ Active Marijuana (3.27% THC)|DRUG: Naltrexone 12 Mg + Inactive Marijuana (0% THC)|DRUG: Naltrexone 25 Mg + Inactive Marijuana (0% THC)|DRUG: Naltrexone 50 Mg + Inactive Marijuana (0% THC)|DRUG: Naltrexone 100 Mg + Inactive Marijuana (0% THC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Test GSK256073 in Patients With Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidaemias|Dyslipidemias
Interventions: DRUG: GSK256073|DRUG: GSK256073|DRUG: GSK256073|DRUG: Placebo|DRUG: Niaspan|DRUG: GSK256073|DRUG: GSK256073
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Real-fire Training on Vascular Function
Status: COMPLETED
Conditions: Vascular Function|Atherothrombosis
Interventions: PROCEDURE: Forearm Vascular Study|PROCEDURE: Badimon Chamber Study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beryllium Infliximab Study: Clinical Interventional Trial
Status: TERMINATED
Conditions: Berylliosis|Beryllium Disease
Interventions: DRUG: Infliximab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: OTHER: Tobacco-Heating Cigarette|OTHER: Snus (Smokeless Tobacco)|OTHER: Tobacco-Burning Cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Objectives of This Study Are Study the Safety, Reactogenicity and Obtain Preliminary Data on the Immunogenicity of Flu-M Quadro, 4-valent Inactivated Split Influenza Vaccine, in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Flu-M Quadro [inactivated split influenza vaccine] with preservative|BIOLOGICAL: Flu-M Quadro [inactivated split influenza vaccine] without preservative|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CATCH - Catheter Infections in Children
Status: COMPLETED
Conditions: Catheter-related Infections
Interventions: DEVICE: Standard polyurethane Central Venous Catheter|DEVICE: Antibiotic impregnated polyurethane CVC (minocycline and rifampicin)|DEVICE: Heparin bonded polyurethane CVC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)
Status: TERMINATED
Conditions: Solid Tumor Malignancy
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Drug Interaction
Interventions: DRUG: Estradiol valerate 2 mg, cyproterone acetate 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy, and Dosing of VIX001 in Patients With Neurological Symptoms of Post Acute COVID-19 Syndrome (PACS).
Status: NOT_YET_RECRUITING
Conditions: Post-Acute COVID-19 Syndrome|Cognitive Impairment|Neurological Complication
Interventions: DRUG: VIX001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel-Loaded Polymeric Micelle and Carboplatin as First-Line Therapy in Treating Patients With Advanced Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel-loaded polymeric micelle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electromyography-Triggered Electrical Stimulation on Trunk Balance and Muscle Thickness in SCI Patients
Status: COMPLETED
Conditions: Spinal Cord Injury Thoracic
Interventions: DEVICE: Neuro Trac Myo Plus Pro|OTHER: Trunk eccentric exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial
Status: COMPLETED
Conditions: Atrial Fibrillation|Arrhythmia
Interventions: DRUG: Rate Control|DEVICE: Ablation Therapy|DRUG: Rate Control|DRUG: Rate control|DRUG: Rate control|DRUG: Rate control|DRUG: Rate Control|DRUG: Rate Control|DRUG: Rate Control|DRUG: Rhythm Control|DRUG: Rhythm control|DRUG: Rhythm control|DRUG: Rhythm control|DRUG: Rhythm control|DRUG: Rhythm control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy
Status: UNKNOWN
Conditions: Pharyngeal Neoplasms|Laryngeal Neoplasms|Carcinoma
Interventions: DEVICE: prothesis voice|PROCEDURE: total laryngectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
Status: NOT_YET_RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: 3,4-Methyl enedioxy methamphetamine|DRUG: Methamphetamine|BEHAVIORAL: Cognitive Behavioral Therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-αIIbβ3 Immunization in Glanzmann Thrombasthenia: Prevalence and Associated Risk Factors: Thrombasthenia Anti-αIIbβ3 Antibodies Study (TAAS)
Status: COMPLETED
Conditions: Glanzmann Thrombasthenia
Interventions: BIOLOGICAL: Antibodies screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetics and Safety/Tolerability Profiles of DA-2811 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Forxiga|DRUG: DA-2811|DRUG: DA-2811|DRUG: DA-2811
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phenotypic and Genotypic Variations of Enterococcus Spp
Status: RECRUITING
Conditions: Isolation of Enterococci From Samples|Demonstration of Enterococci Antibiotic Susceptibility|Detection of Strains Enterococci Produce Biofilm|Studying Effect of Nanoparticles on Enterococci Antimicrobial Resistance|Studying Effect of Nanoparticles on Enterococci Biofilm|Genotyping of Enterococci
Interventions: DIAGNOSTIC_TEST: Culture|DIAGNOSTIC_TEST: Staining:|DIAGNOSTIC_TEST: Biochemical reactions:|DIAGNOSTIC_TEST: VITEK|DIAGNOSTIC_TEST: Antibiotic sensitivity test|DIAGNOSTIC_TEST: nanoparticles effect|DIAGNOSTIC_TEST: The biofilm formation activity|DIAGNOSTIC_TEST: molecular diagnosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Probiotics on Low-grade Inflammation, Microbiota and Risk Factors for Metabolic Syndrome in Obese Children
Status: COMPLETED
Conditions: Metabolic Syndrome|Inflammation|Obesity
Interventions: DIETARY_SUPPLEMENT: Ls-33
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Raptiva in Adults With Moderate to Severe Plaque Psoriasis Who Are Candidates for Systemic Therapy
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Raptiva (efalizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reducing Reintubation Risk in High-Risk Cardiac Surgery Patients With High-Flow Nasal Cannula
Status: RECRUITING
Conditions: Intubation|Cardiovascular Surgical Procedure
Interventions: OTHER: Recommendation for high flow nasal cannula oxygen therapy order set|OTHER: Provider choice standard care order set
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effect of a Follow up Tele-rehabilitation Program for Chronic Obstructive Lung Disease vs. Standard Follow up
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: BEHAVIORAL: Tele rehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesh Fixation Versus Non Fixation in Laparoscopic Inguinal Hernioplasty
Status: NOT_YET_RECRUITING
Conditions: Laparoscopic|Inguinal Hernia|Hernioplasty
Interventions: PROCEDURE: fixation of conventional polypropylene mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Double Crossover Casein Type Tolerance Trial
Status: RECRUITING
Conditions: Dairy Intolerance|Healthy Adults
Interventions: OTHER: Conventional lactose-free cow's milk|OTHER: Nonconventional (A2) cow's milk|OTHER: Nonconventional (A2) lactose-free cow's milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy, Bone Marrow Transplant, and Post Transplant Cyclophosphamide for Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Trial of Two Pneumococcal Conjugate Vaccines (PncCRM and PncOMPC) for Prevention of Acute Otitis Media Due to Vaccine Serotypes
Status: COMPLETED
Conditions: Otitis Media|Pneumococcal Infections
Interventions: BIOLOGICAL: 7-valent pneumococcal-CRM197 conjugate vaccine|BIOLOGICAL: 7-valent pneumococcal-OMPC conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Prime Time for Superficial Femoral Artery (SFA) - The SFA Study
Status: TERMINATED
Conditions: Peripheral Vascular Disease
Interventions: PROCEDURE: Cryoplasty (PolarCath peripheral balloon catheter)|PROCEDURE: Laser Angioplasty (Spectranetics)|PROCEDURE: SilverHawk Atherectomy|DEVICE: Viabahn Endograft|PROCEDURE: Angioplasty/Stent (Guidant "Absolute" stent)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy
Status: RECRUITING
Conditions: Symptomatic Neurogenic Orthostatic Hypotension|MSA - Multiple System Atrophy
Interventions: DRUG: Ampreloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness on Family Cohesion and Happiness of Using Social Media to Enhance Happiness Accounts for Late-Stage Cancer Patients and Their Families
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: OTHER: life review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Genotype-Driven Treatment of Advanced Non-small Cell Lung Cancer Based on mRNA Expression of ERCC1 & RRM1 as First-line Chemotherapy
Status: COMPLETED
Conditions: Non-small Cell Lung Carcinoma
Interventions: DRUG: chemotherapy|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Subjects With Genotype 1 Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C|Hepatitis C Virus|HCV
Interventions: DRUG: ABT-493/ABT-530
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREPARE, Prematurity Reduction by Pre-eclampsia Care
Status: COMPLETED
Conditions: Pre-Eclampsia|Premature Birth
Interventions: DIAGNOSTIC_TEST: FullPIERS and sFlit/PLGF (Soluble fms-Like Tyrosine Kinase-1-to-Placental Growth Factor Ratio)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Green Coffee Effect on Metabolic Syndrome
Status: COMPLETED
Conditions: Supportive Care|Metabolic Syndrome|Obesity|Hypertension
Interventions: DIETARY_SUPPLEMENT: Green coffee been extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ascending Dose Study of the Safety and Tolerability of Alirocumab (SAR236553/REGN727) in Japanese Healthy Volunteers
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Alirocumab (Solution)|DRUG: Alirocumab (Lyophilized formulation)|DRUG: Placebo (Solution)|DRUG: Placebo (Lyophilized formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AMG 811 in Subjects With Discoid Lupus Erythematosus
Status: TERMINATED
Conditions: Cutaneous Lupus|Discoid Lupus|Lupus|Systemic Lupus Erythematosus
Interventions: DRUG: AMG811|DRUG: AMG811 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser
Status: RECRUITING
Conditions: Hypertrophic Scar|Burn Scar
Interventions: DEVICE: Luminis ultrapulse fractional ablative carbon dioxide laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Standard Process 21 Day Purification Program Project
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: OTHER: Standard Process 21 Day Purification Program (SPPP)|OTHER: Standard Process 21 Day Purification Program (SPPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Muscle Derived Cells Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: BIOLOGICAL: AMDC-USR (iltamiocel)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Conditioning in Heart Attack Patients
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Catechin High Contain Greentea Extract on Improvement of Cognitive Function
Status: COMPLETED
Conditions: Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Catechin high contain greentea extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of New Generation Drug Eluting Stents Associated With an Ultra Short Duration of Dual Antiplatelet Therapy. Design of the Short Duration of Dual antiplatElet Therapy With SyNergy II Stent in Patients Older Than 75 Years Undergoing Percutaneous Coronary Revascularization.
Status: COMPLETED
Conditions: Stable Angina|Silent Myocardial Ischemia|Acute Coronary Syndrome
Interventions: PROCEDURE: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Synergy II stent|PROCEDURE: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Omega stent|PROCEDURE: Percutaneous Coronary Intervention (PCI) with short DAPT duration with Rebel stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Transitional Palliative Care Model on Patients With End-stage Renal Failure
Status: COMPLETED
Conditions: Palliative Care|Renal Failure, End-stage
Interventions: BEHAVIORAL: Transitional community based palliative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of High-Dose Ranibizumab for Polypoidal Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: ranibizumab 2.0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stabilizing Group Treatment of Complex Trauma: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Dissociative Identity Disorder|Dissociative Disorder
Interventions: BEHAVIORAL: Conventional individual treatment|BEHAVIORAL: Stabilizing group treatment for PTSD|BEHAVIORAL: Stabilizing group treatment for Dissociative disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness Of Intravenous TXA on Reducing Perioperative Blood Loss For Patients Undergoing PAO
Status: WITHDRAWN
Conditions: Bleeding
Interventions: DRUG: Tranexamic Acid|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aerobic Exercises and Yoga Exercises in Axial Spondyloarthritis
Status: RECRUITING
Conditions: Axial Spondyloarthritis and Ankylosing Spondylitis
Interventions: OTHER: yoga based exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIRTUAL REALITY TECHNOLOGY FOR CEREBRAL PALSY
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: conventional upper extremity therapeutic program|OTHER: full immersive VRapeutic software gaming technology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention for Veterans With Depression, Substance Disorder, and Trauma
Status: COMPLETED
Conditions: Depressive Symptoms|Substance-related Disorders|Posttraumatic Stress Disorders
Interventions: BEHAVIORAL: Cognitive Processing Therapy-Modified (CPT-M)|BEHAVIORAL: Integrated Cognitive Behavioral Therapy (ICBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ixabepilone and Ketoconazole in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ixabepilone|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sinew Acupuncture for Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Sinew acupuncture|OTHER: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of Shatavari Supplementation on Bone and Skeletal Muscle Health in Healthy Postmenopausal Women
Status: COMPLETED
Conditions: Muscle Weakness|Osteoporosis, Postmenopausal
Interventions: DIETARY_SUPPLEMENT: Shatavari|DIETARY_SUPPLEMENT: Magnesium stearate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compass Hinge Stabilization of Knee Dislocations: A Randomized Trial
Status: COMPLETED
Conditions: Knee Dislocation
Interventions: DEVICE: Compass Universal Hinge External Fixator|PROCEDURE: Non-invasive External Knee Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Humira in Treatment of Pyoderma Gangrenosum
Status: WITHDRAWN
Conditions: Pyoderma Gangrenosum
Interventions: DRUG: Humira|DRUG: Humira
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Purpose of This Study is to Assess Clinical Efficacy and Safety of Berovenal® Intended to Promote Treatment and to Expedite Chronic Diabetic Foot Ulcer Healing
Status: RECRUITING
Conditions: Diabetic Foot Ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT