pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Methods to Reduce Blood Loss in Abdominal Myomectomy
Status: UNKNOWN
Conditions: Abdominal Myomectomy|Blood Loss
Interventions: DRUG: Misoprostol 200mcg Tab vaginal|DRUG: Oxytocin|DRUG: Carbetocin|PROCEDURE: pericervical hemostatic tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Impact of AbbVie Care Patient Support Program on Clinical, Health Economic and Patient Reported Outcomes, in Crohn's Disease, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis and Axial Spondyloarthritis, in the Portuguese National Health Service
Status: COMPLETED
Conditions: Crohn's Disease|Ulcerative Colitis (UC)|Rheumatoid Arthritis (RA)|Psoriatic Arthritis|Psoriasis|Ankylosing Spondylitis (AS)|Non-radiographic Axial Spondyloarthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms
Status: COMPLETED
Conditions: Xerostomia
Interventions: OTHER: Biotene mouthwash|OTHER: Mineral Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Drug/Agent Toxicity by Tissue/Organ|Lung Cancer|Radiation Toxicity
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: etoposide|DRUG: paclitaxel|DRUG: topotecan hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Electromagnetic Stimulation Therapy for Chronic Prostatitis and Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Prostatitis|Chronic Pelvic Pain Syndrome
Interventions: DEVICE: Electromagnetic Stimulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Breast Massage Necessary to Find Sentinel Lymph Node?
Status: COMPLETED
Conditions: Sentinel Lymph Node|Breast Cancer
Interventions: PROCEDURE: Sentinel lymph node biopsy|PROCEDURE: Breast massage|PROCEDURE: Blue dye injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mnaual Therapy in Treatment of Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing Dolutegravir and Associated Nucleoside / Nucleotide Reverse Transcriptase Inhibitors Backbone
Status: COMPLETED
Conditions: HIV-1 Infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing CHG I.V. Securement Dressing With Transparent Dressing for Evaluation of Antimicrobial Efficacy
Status: TERMINATED
Conditions: Central Venous Catheter Exit Site Infection|Catheter-Related Infections
Interventions: DEVICE: 3M™ Tegaderm™ CHG I.V. Securement Dressing|DEVICE: 3M™ Tegaderm™ Transparent Film Dressing 1626W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Extended Versus Conventional Duration of Enoxaparin Prophylaxis (i.e., Preventive Treatment) for Venous Thromboembolism (VTE, i.e., Blood Clots in the Veins) and Bleeding Event Risk in a Population With Acute Medical Illness
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Thromboembolism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trichloroacetic Acid for Endoscopic Tracho-esophageal Fistula Repair
Status: UNKNOWN
Conditions: Tracheo Esophageal Fistula
Interventions: PROCEDURE: Endoscopic repair of recurrent TEF by trichloroacetic acid aplications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Hyaluronic Acid Gel and Photobiomodulation on Wound Healing After Surgical Gingivectomy
Status: COMPLETED
Conditions: Gingival Enlargement
Interventions: DEVICE: Photobiomodulation|OTHER: Hyaluronic acid after photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Neoadjuvant Treatment in Patients With Pancreatic Cancer That is Potentially Resectable
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|RADIATION: Radiotherapy|DRUG: Tarceva|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRANSDERMAL HRT RELIEVING POSTMENOPAUSAL SYMPTOMS
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Transdermal Hormone Replacement Therapy|DRUG: Transdermal Nanoformulation|DRUG: Transdermal formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specific Immunotherapy for Allergic Child
Status: UNKNOWN
Conditions: Allergic Rhinitis|Allergic Asthma|Grass Allergy
Interventions: DEVICE: Injex|PROCEDURE: SCIT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation
Status: UNKNOWN
Conditions: Lung Inflammation|Sarcoidosis
Interventions: RADIATION: PET/CT scan|OTHER: LPS Challenge|OTHER: Saline Challenge|DIAGNOSTIC_TEST: Blood and urine sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Injection of Dorsal Scapular n at Different Levels, Dose it Make Difference?
Status: COMPLETED
Conditions: Pain, Chronic
Interventions: DRUG: Depo medrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Acupuncture Efficacy for Medical Students' Examination Anxiety
Status: COMPLETED
Conditions: Anxiety|Anxiety, Exam
Interventions: OTHER: Auricular acupuncture|OTHER: Sham Auricular acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Twice High Dose External Beam Radiotherapy by Image-guided Tomotherapy for Organ-confined Prostate Cancer Treatment Emulating High Dose Radiation (HDR) Brachytherapy
Status: TERMINATED
Conditions: Prostate Adenocarcinoma|Radiotherapy; Complications|Tomotherapy
Interventions: RADIATION: tomotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug-Drug Interaction Study of Rucaparib
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Caffeine|DRUG: Warfarin|DRUG: Omeprazole|DRUG: Midazolam|DRUG: digoxin|DRUG: Vitamin K|DRUG: Rucaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rural Access to Physical Therapy for Osteoarthritis Rehabilitation - Pilot
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: RAPTOR protocol: hybrid in-person + telehealth physical therapy services
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Lumbar Stabilization Exercises With and Without Jaw Movements in Non-specific Low Back Pain.
Status: COMPLETED
Conditions: Chronic Nonspecific Low Back Pain|Core Stability|Jaw Movements|Temporomandibular Joint
Interventions: OTHER: core stability exercises with teeth clenching|OTHER: core stability exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis
Status: UNKNOWN
Conditions: Mucositis Oral
Interventions: OTHER: Benzydamine Hydrochloride|COMBINATION_PRODUCT: Solcoseryl and pumpkin seed oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Nature Walks or Exercise as a Group Activity, the Effect Well-being, Sleep and Activity.
Status: COMPLETED
Conditions: Health Promotion|Multimorbidity
Interventions: BEHAVIORAL: Nature based facilitated group intervention|BEHAVIORAL: Exercise in group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug Interactions of Echinacea, Ginseng, and Ginkgo Biloba Taken With Lopinavir/Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gingko Biloba|DRUG: Echinacea purpurea|DRUG: Panax ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Instrumented vs. Conventional Perturbation-based Balance Training for Fall Prevention
Status: TERMINATED
Conditions: Fall Risk, Fall Prevention
Interventions: OTHER: Training on perturbation treadmill|OTHER: Exercises of dynamic stability under unstable conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Foster 100/6mg NEXThaler|DRUG: Foster 100/6mg pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alemtuzumab and Rituximab in the Treatment of Refractory Autoimmune Cytopenias
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura|Anemia, Hemolytic, Autoimmune
Interventions: DRUG: Alemtuzumab, Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of GANFORT® Ophthalmic Solution in Chinese Patients With Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.03% plus timolol 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Screening of Alberta Asbestos Exposed Workers for Lung Cancer and Mesothelioma
Status: TERMINATED
Conditions: Lung Cancer|Mesothelioma
Interventions: PROCEDURE: Low-dose computed tomography Annual scan x3|PROCEDURE: Low-dose computed tomography Baseline scan only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial
Status: RECRUITING
Conditions: Asymmetric Hearing Loss|Single-sided Deafness|Unilateral Deafness
Interventions: DEVICE: Cochlear Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK3359609 Plus Tremelimumab for the Treatment of Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: feladilimab|DRUG: Tremelimumab|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Regimen With Sodium Valproate for Severe Hemophilia: a Single-arm, Phase 1, Pilot Trial.
Status: RECRUITING
Conditions: Hemophilia
Interventions: DRUG: Sodium valproate extended-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of Infloran (TM) in Treating Acute Childhood Diarrhea in Phramongkutklao Hospital
Status: UNKNOWN
Conditions: Acute Diarrhea
Interventions: DRUG: Probiotic - Infloran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using Nevirapine to Prevent Mother-to-Child HIV Transmission During Breastfeeding
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Nevirapine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer
Status: COMPLETED
Conditions: Metastatic Cancer|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: Acetaminophen|DRUG: Morphine Sulfate|OTHER: Questionnaire administration|PROCEDURE: Quality-of-life assessment|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate|DRUG: Fluticasone furoate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safe Excipient Exposure in Neonates and Small ChildreN
Status: UNKNOWN
Conditions: Excipient Exposure|Neonatal|Pediatric
Interventions: OTHER: Exposure to ethanol|OTHER: Exposure to propylene glycol|OTHER: Exposure to benzyl alcohol|OTHER: Exposure to acesulfam potassium|OTHER: Exposure to aspartame|OTHER: Exposure to glycerol|OTHER: Exposure to sorbitol|OTHER: Exposure to methyl-p-hydroxybenzoate|OTHER: Exposure to propanyl-p-hydroxybenzoate|OTHER: Exposure to polysorbate-80
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extracellular Impact of Ultrasound-induced Blood-brain Barrier Disruption
Status: RECRUITING
Conditions: Brain Tumor
Interventions: DEVICE: InSightec's ExAblate Neuro Model 4000 Type 2.0 (220 KHz) system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A-Part® Gel as Adhesion Prophylaxis After Major Abdominal Surgery Versus a Non-treated Group
Status: COMPLETED
Conditions: Adhesions|Abdominal Cavity
Interventions: DEVICE: A-Part® Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oxytocin, Carbetocin and Misopristol for Treatment of Postpartum Hemorrhage: A Multicentric Randomized Trial
Status: UNKNOWN
Conditions: Postpartum Hemorrhage
Interventions: DRUG: carbetocin|DRUG: misopristol|DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lenacapavir Taken Twice a Year for HIV Pre-Exposure Prophylaxis (PrEP)
Status: NOT_YET_RECRUITING
Conditions: Pre-Exposure Prophylaxis of HIV Infection
Interventions: DRUG: Lenacapavir Injection|DRUG: Lenacapavir Tablet|DRUG: Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Education Given at Different Times Before a Breast Biopsy
Status: COMPLETED
Conditions: Breast Cancer|Educational Problems|Bypass Complication
Interventions: OTHER: Written, Oral and Visual Education|OTHER: Written, Oral and Visual Education|OTHER: Written, Oral and Visual Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: ISB 2001|DRUG: ISB 2001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating NeuroVision's Neural Vision Correction (NVC) Myopia Treatment
Status: TERMINATED
Conditions: Myopia
Interventions: DEVICE: NeuroVision's NVC treatment for Low Myopia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Desflurane and Sevoflurane in Pediatrics With Elevated Liver Enzymes
Status: UNKNOWN
Conditions: Liver Functions Tests
Interventions: DRUG: Desﬂurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Convection-enhanced Delivery of OS2966 for Patients With High-grade Glioma Undergoing a Surgical Resection
Status: TERMINATED
Conditions: Glioma, Malignant|High Grade Glioma|Glioblastoma|Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: OS2966|DRUG: Gadoteridol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Effect of 2 Pen Devices on HbA1c
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin Lispro|DRUG: Huminsulin Regular|DEVICE: HumaPen Memoir|DEVICE: HumaPen Luxura
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasmakinetic Enucleation of the Prostate and Open Prostatectomy to Treat Large Prostates
Status: COMPLETED
Conditions: Benign Prostate Hyperplasia
Interventions: PROCEDURE: PkEP|PROCEDURE: OP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Clinical Safety/Tolerability and Exploratory Efficacy of EHT 0202 as Adjunctive Therapy to Acetylcholinesterase Inhibitor in Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: EHT 0202 etazolate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of a New Gene Involved in Hereditary Lipodystrophy
Status: COMPLETED
Conditions: Lipodystrophy
Interventions: GENETIC: Amplification by PCR and direct sequencing on the entire coding sequence and intron-exons boundaries of the candidate gene|BIOLOGICAL: Perform blood cells and fibroblasts biochemical and immuno-labeled investigations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Implementation of the Specific Treatment Of Problems of the Spine Approach in Bangladesh
Status: RECRUITING
Conditions: Chronic Low-back Pain
Interventions: OTHER: Usual physiotherapy care|OTHER: Individualized (STOPS) physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Allergy Towards Grass and Bronchial Inflammation - Related to Immunotherapy and Exhaled Nitrogen Oxide
Status: UNKNOWN
Conditions: Asthma, Bronchial|Allergic Rhinitis|Hypersensitivity, Immediate
Interventions: BIOLOGICAL: Specific immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: TIME in Immunotherapy Combined With nCRT for Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: PD-1 inhibitor|DRUG: Capecitabine|RADIATION: Long-course radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Relationship Between Clinical and Paraclinical Markers During Situations of Cachexia and Pre-cachexia in Patients Over 70 Years With Colorectal Surgery
Status: COMPLETED
Conditions: Colorectal Tumor
Interventions: PROCEDURE: Biopsy of adipose and muscular tissue|OTHER: Blood sampling|OTHER: Calorimetry|OTHER: Impedance measure|OTHER: Evaluation of nutritional status|OTHER: Evaluation of physical performance|OTHER: Evaluation of muscular strength|OTHER: Evaluation of emotional status|OTHER: Evaluation of functional status
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Support Via Technology: Living and Learning With Advancing Dementia-REVISED
Status: RECRUITING
Conditions: Caregiver Burden
Interventions: BEHAVIORAL: STELLA-R Curriculum|BEHAVIORAL: Unrestricted Access|BEHAVIORAL: Limited Access
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acute Ventilatory Response to Hypoxia During Sedation With Dexmedetomidine Compared to Propofol in Healthy Male Volunteers
Status: COMPLETED
Conditions: Hypoxia|Anesthetics|Conscious Sedation|Hypercapnia
Interventions: PROCEDURE: Hypoxic ventilatory response|PROCEDURE: Hypercapnic ventilatory response
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Water and Glucose Drinks on Cardiovascular Function in Subjects With and Without Postprandial Hypotension
Status: COMPLETED
Conditions: Autonomic Nervous System Diseases|Baroreflex Failure|Blood Pressure|Hypotension
Interventions: OTHER: Glucose|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Polyphenols on Peripheral Vascular Disease.
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DIETARY_SUPPLEMENT: dark chocolate with crossover to milk chocolate|DIETARY_SUPPLEMENT: milk chocolate with crossover to dark chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Differentiation Induction in Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: all-trans retinoic acid (ATRA)|DRUG: Valproic acid|DRUG: Theophyllin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of CPT-11 Plus Platinum Analogues Regimens and UGT1A1 Genotypes in Solid Tumors
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Non-small Cell Lung Cancer|Cervical Cancer|Ovarian Cancer|Gastric Cancer (Inoperable and Recurrent)
Interventions: DRUG: CPT-11|DRUG: Platinum analogues
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Disturbances in Surgical Patients With GI Cancers: A Quantitative and Qualitative Analysis
Status: NOT_YET_RECRUITING
Conditions: GI Cancers|Gastrointestinal Cancer
Interventions: OTHER: Sleeping Disturbances
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study of Intralesional Injection of M4N in Patients With Refractory Malignant Tumors of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: M4N
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of GABA-A Receptors in Parkinson Disease-Transdermal Flumazenil Arm
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Clarithromycin (Not used as of 4/2020)|DRUG: Placebo (Not used as of 4/2020)|DRUG: Transdermal flumazenil (Added 4/2020)|DRUG: Placebo (Added 4/2020)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase I, Placebo-Controlled, Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Thalidomide in Subjects With HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study on the Bioequivalence of Amisulpride Orally Disintegrating Tablets in Human Body
Status: RECRUITING
Conditions: Bioequivalence|Schizophrenia
Interventions: DRUG: Drug: Test (T) Amisulpride orally disintegrating tablets (200mg). Produced and supplied by Zezheng (Shanghai) Biotechnology Co., Ltd.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plantar Compartment Block Versus Sciatic Block in Hallux Valgus Ambulatory Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: PLANTAR BLOCK|PROCEDURE: Sciatic popliteal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Virtual Reality Cognitive Training for Older Adults With Mild Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Mild Cognitive Impairment|Older Adults
Interventions: BEHAVIORAL: fi-VR Cognitive Training|BEHAVIORAL: Traditional Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Medicinal Product Cardionat® Using in Health Athlete Volunteers
Status: COMPLETED
Conditions: Stroke, Not Specified as Hemorrhage or Infarction|Angina Pectoris
Interventions: DRUG: оral intake of study drug capsules; study drug - Cardionat ® (trimethylhydrazinium propionate dihydrate), oral capsules 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatment Effects of Atorvastatin on Hemostasis and Skin Microcirculation in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Dyslipidemia
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Portico and Navitor India Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis|Aortic Valve Failure|Aortic Insufficiency|Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Two Induction Means on Emergence After General Anesthesia
Status: UNKNOWN
Conditions: Mean Arterial Pressure|Heart Rate
Interventions: DRUG: Fentanyl|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Complete Axillary Lymph Node Dissection With Axillary Radiation Therapy in Treating Women With Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: axillary lymph node dissection|PROCEDURE: lymphoscintigraphy|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Safety, Tolerability and PK Study of Ondansetron and Hylenex Recombinant in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ondansetron|DRUG: Ondansetron + Hylenex|DRUG: Zofran ODT|DRUG: Ondansetron solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resetting the Default: Improving Provider-patient Communication to Reduce Antibiotic Misuse
Status: COMPLETED
Conditions: Communication|Anti-Bacterial Agents|Decision Making|Personal Satisfaction
Interventions: BEHAVIORAL: Education|BEHAVIORAL: Communication Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Bioequivalence Study of Clopidogrel 75 mg in Two Tablet Formulations Relative to Reference Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DRUG: Clop F1|DRUG: Clop F2|DRUG: Innovator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Unilateral Nerve-Sparing Cryoablation for Low-Risk, Clinically Localized, Unilateral Prostate Cancer
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Unilateral Nerve-Sparing Cryoablation of the Prostate|DEVICE: Precise Cryoablation System with IceRod Needles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Tablet Regimen (STR) Simplification Study for HIV-1 Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Efavirenz (EFV), Emtricitabine (FTC), Tenofovir DF (TDF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vestibular and Motor Functions in Children With Hemiplegic Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Hemiplegic Cerebral Palsy
Interventions: OTHER: Neurodevelopmental technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed Episode
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lamotrigine + Aripiprazole|DRUG: Lamotrigine + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Massage Applied by the Parents in Hospitalized Premature Birth (PreMas)
Status: COMPLETED
Conditions: Massage|Premature Infant|Premature Birth|Preterm Infant
Interventions: BEHAVIORAL: Protocol of massage therapy and kinesiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Prospective Randomized Trial of the Effect of Rivaroxaban on Survival and Development of Complications of Portal Hypertension in Patients With Cirrhosis
Status: UNKNOWN
Conditions: Cirrhosis
Interventions: DRUG: Rivaroxaban|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telmisartan Effectiveness on Left Ventricular Mass Reduction (TELMAR) as Assessed by MRI, in Patients With Mild to Moderate Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Metoprolol succinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Perineal Protective Package Application on Pelvic Floor in Labor
Status: NOT_YET_RECRUITING
Conditions: Pregnancy|Labor|Pelvic Floor
Interventions: OTHER: Experimental: perineal package application group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Respiratory Tract Illness
Interventions: BIOLOGICAL: RSVpreF|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture
Status: COMPLETED
Conditions: Cholangiocarcinoma|Biliary Stricture|DNA Methylation|Brush Cytology
Interventions: DIAGNOSTIC_TEST: Control|DIAGNOSTIC_TEST: Cholangiocarcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Atopic Dermatitis: Early Gene Expression Changes as Predictors of Therapeutic Response to Narrow-band UVB Treatment
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: OTHER: narrow-band UVB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ability of Carotid Sonography and Inferior Vena Cava Sonography for the Prediction of Post-induction Hypotension in Hypertensive Patients
Status: UNKNOWN
Conditions: General Anesthesia
Interventions: BIOLOGICAL: carotid sonography and inferior vena cava sonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of L-PRF and A-PRF in Ridge Preservation
Status: COMPLETED
Conditions: Atrophic Maxilla|Ridge Preservation
Interventions: OTHER: L-PRF|OTHER: A-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual Disease
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: haploid allogeneic NK cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Clinic-based vs. Self-use of a Misoprostol-only Regimen for Induced Abortion
Status: UNKNOWN
Conditions: Induced Abortion|First Trimester Abortion
Interventions: BEHAVIORAL: Misoprostol sourced from clinics|BEHAVIORAL: Misoprostol sourced from PMVs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Fasting Study of Divalproex Sodium Extended-Release Tablets 500 mg to Depakote ER® Tablets 500 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Divalproex Sodium Extended-Release Tablets 500 mg|DRUG: Depakote ER® Tablets 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Surgical Outcomes of Simple Interrupted Versus Running Epidermal Sutures in Full-thickness Skin Graft Placement
Status: RECRUITING
Conditions: Skin Graft Scar
Interventions: PROCEDURE: Simple interrupted suturing technique|PROCEDURE: Running suturing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia)
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: IMR-687|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet-rich Fibrin on Clinical and Patient-centered Outcomes of Third Molar Extractions
Status: COMPLETED
Conditions: Oral Surgery
Interventions: PROCEDURE: Third-molar extraction using platelet-rich fibrin as a filling of the alveolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis
Status: COMPLETED
Conditions: Uveitis, Posterior|Uveitis, Intermediate|Panuveitis
Interventions: DRUG: Placebo|DRUG: LX211|DRUG: LX211|DRUG: LX211
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine
Status: TERMINATED
Conditions: Glioblastoma Multiforme|Astrocytoma, Grade III|Anaplastic Ependymoma|Clear Cell Ependymoma|Ependymoma
Interventions: BIOLOGICAL: Heat Shock Protein Peptide Complex-96 (HSPPC-96)|PROCEDURE: Tumor Resection|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FLOWS-HF : Feasibility of Lymphatic Offloading With Stenting in Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Chronic Heart Failure
Interventions: PROCEDURE: Lymphatic Decompression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Nonalcoholic Fatty Liver Disease With Probiotics and Prebiotics
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease
Interventions: DRUG: Lepicol probiotic & prebiotic formula|OTHER: Simple lifestyle advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Active Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Anifrolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea
Status: NOT_YET_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: BEHAVIORAL: routine rehabilitation treatment|PROCEDURE: Stellate ganglion block|DRUG: Lidocaine Hydrochloride|PROCEDURE: Placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions: DRUG: ADX-038|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Assessment of Low-cost Infant Incubator in Monitoring Temperature and Treating Hypothermia in Infants
Status: UNKNOWN
Conditions: Neonatal Hypothermia
Interventions: DEVICE: Continuous temperature monitor|DEVICE: Neonatal Incubator|DEVICE: Patient monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury
Status: ENROLLING_BY_INVITATION
Conditions: Traumatic Brain Injury
Interventions: DRUG: Atorvastatin Calcium|DRUG: Minocycline Hydrochloride|DRUG: Candesartan Cilexetil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Versus Conventional Altered Cast Techniques For Constructing Mandibular Distal Extension Removable Partial Dentures Using Digitally Fabricated Frameworks: Alveolar Bone Height Changes
Status: RECRUITING
Conditions: Denture, Partial, Removable
Interventions: OTHER: Removable Partial Denture Construction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: KVD900|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Warm Needle Acupuncture vs Needle Acupuncture
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Warm needle acupuncture|DEVICE: Needle acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Efficacy and Safety of DP-R202 and Anplag in Patients With Artery Occlusive Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: DP-R202|DRUG: Anplag tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Two Anti-T-lymphocyte Immune Globulin (ATG-F) Induction Regimens in Anew Kidney Transplant Patients
Status: COMPLETED
Conditions: De Novo Kidney Transplant Patients
Interventions: DRUG: ATG-F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Empagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photoallergic Potential of 6% Bemotrizinol
Status: COMPLETED
Conditions: Photoallergic Response
Interventions: DRUG: 6% Bemotrizinol in sunscreen formulation|DRUG: 6% Bemotrizinol in petrolatum|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores
Status: WITHDRAWN
Conditions: Pain, Postoperative
Interventions: DRUG: Brivoligide Injection 660 mg/6 mL|DRUG: Placebo 6 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: PROMUS Coronary Stent System|DEVICE: PROMUS Element Coronary Stent System|DRUG: Aspirin|DRUG: Thienopyridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: DRUG: systemic proteolytic enzyme (Tibrolin)|DRUG: Amoxicillin 500mg+metronidazole 500mg+ doliprane 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Combined With Toripalimab and SOX Regimen in the First-line Treatment of Advanced Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Status: RECRUITING
Conditions: Metastatic Gastric Cancer
Interventions: DRUG: fruquintinib＋toripalimab + SOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Human Urinary Kallidinogenase Combined With Endovascular Therapy in Acute Ischemic Stroke With Large Vessel Occlusion
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Experimental: Human Urinary Kallidinogenase|DRUG: Placebo Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REMASTer: REcurrent Brain Metastases After SRS Trial
Status: RECRUITING
Conditions: Brain Metastases|Radiation Necrosis|Recurrent Tumor|Recurrent Metastases
Interventions: PROCEDURE: Radiation Therapy|DRUG: Steroid Therapy|PROCEDURE: Laser Interstitial Thermal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection
Status: NOT_YET_RECRUITING
Conditions: Rectal Cancer
Interventions: BIOLOGICAL: Mesenchymal Stem Cells Derived Exosomes|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION