pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nedaplatin Versus Cisplatin and Capecitabine Versus Fluorouracil in IC + CCRT for Locoregionally Advanced NPC
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: docetaxel, nedaplatin, and capecitabine|DRUG: nedaplatin|DRUG: docetaxel, cisplatin, and fluorouracil|DRUG: cisplatin|DRUG: docetaxel, cisplatin, and capecitabine|DRUG: docetaxel, nedaplatin, and fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Of Itraconazole In Chronic Cavitary Pulmonary Aspergillosis
Status: COMPLETED
Conditions: Chronic Cavitary Pulmonary Aspergillosis
Interventions: DRUG: Itraconazole|DRUG: treatment in cavitary pulmonary aspergillosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: TAVR with CENTERA THV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of CC7 Transfer in Stroke Subtypes
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Ischemic|Stroke Hemorrhagic|Spastic Hemiparesis
Interventions: PROCEDURE: Contralateral C7 root transfer for the treatment of spastic hemiparesis.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Acidophilus L92 on Markers of Allergic Inflammation by Nasal Provocation With Grass Pollen
Status: WITHDRAWN
Conditions: Hayfever
Interventions: BIOLOGICAL: Lactobacillus acidophilus L-92
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: ESK-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of ASC16 Tablets in Healthy Volunteers in China
Status: COMPLETED
Conditions: HCV
Interventions: DRUG: Danoprevir|DRUG: Ritonavir|DRUG: Ravidasvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: CDX-1401|DRUG: MPDL3280A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study, Single-arm, Multicentre, Observational to Evaluate Safety and Effectiveness of Stent Ultimaster Tansei Coronary Stent in Complex Coronary Lesions.
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Heart Disease|Coronary Artery Disease
Interventions: DEVICE: TANSEI stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
Status: RECRUITING
Conditions: Change in Bone Mineral Density|Bone Loss
Interventions: DRUG: LF111 (drospirenone 4 mg oral tablet) or drospirenone (DRSP) 3.5 mg chewable tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Dry Needling and Spinal Manipulation vs. Conventional PT for Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: OTHER: electric dry needling, manipulation|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study on SHR6390 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: SHR6390(100mg)|DRUG: SHR6390(125mg)|DRUG: SHR6390(150mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosuvastatin Prevent Contrast Induced Acute Kidney Injury in Patients With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Chronic Kidney Disease
Interventions: DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gulf War Digestive Health Study
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Small Intestinal Bacterial Overgrowth
Interventions: DRUG: Placebo|DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IM Ketamine vs Midazolam for Suicidal ER Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression, Unipolar|Depression, Bipolar|Suicidal Ideation
Interventions: DRUG: Ketamine hydrochloride injection|DRUG: Midazolam injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychotherapy Intervention for Latinos With Adv Cancer
Status: RECRUITING
Conditions: Solid Tumor|Solid Tumor, Adult|Solid Tumor, Unspecified, Adult
Interventions: BEHAVIORAL: Meaning Centered Psychotherapy for Latinos|BEHAVIORAL: Functional Assessment of Cancer Therapy - Spiritual Well-Being Scale|BEHAVIORAL: Meaning Centered Psychotherapy for Latinos for Waitlist Control Patients|BEHAVIORAL: Pre-assessment questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pragmatic Research in Healthcare Settings to Improve Diabetes and Obesity Prevention and Care for Our Program
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes|Weight Loss|Diet Habit
Interventions: BEHAVIORAL: MAINTAIN PRIME Lifestyle Coaching|BEHAVIORAL: Control tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp Treatments
Status: RECRUITING
Conditions: Pulpitis - Irreversible|Apical Periodontitis
Interventions: PROCEDURE: Pulpotomy for mature permanent mandibular molars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development and Effectiveness of Cognitive Behavioral Therapy Based Weight Control Mobile Application "BI'KILO"
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Loss|Obesity|Overweight and Obesity|Eating Behavior|Eating Habit
Interventions: OTHER: BI'KILO Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failure
Status: COMPLETED
Conditions: Pulmonary Hypertension|Diastolic Heart Failure
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HILT and US Therapies in Adhesive Capsulitis
Status: COMPLETED
Conditions: Adhesive Capsulitis of Shoulder
Interventions: DEVICE: Ultrasound Therapy (US)|DEVICE: High-Intensity Laser Therapy (HILT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects
Status: COMPLETED
Conditions: Tuberculosis|Tuberculosis, Pulmonary
Interventions: DRUG: 1800 mg TBI-223|DRUG: 2400mg TBI-223|DRUG: 3000mg TBI-223|DRUG: TBI-223 Placebo|DRUG: TBI-223 Placebo|DRUG: TBI-223 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cytoreductive Surgery Combined With HIPEC and Chemotherapy for Gastric Cancer With Peritoneal Metastasis
Status: UNKNOWN
Conditions: Stomach Neoplasm
Interventions: PROCEDURE: Cytoreductive surgery|PROCEDURE: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Fluoropyrimidine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Objective Vision Evaluation of Two Cosmetic Contact Lenses
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: JJVC Investigational Contact Lens|DEVICE: 1-DAY ACUVUE® DEFINE® Radiant Sweet™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of an Online Mindfulness-based Intervention for Children With Attention-Deficit/Hyperactivity Disorder
Status: RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: mindfulness-based intervention|BEHAVIORAL: child behavior management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: Intravenous thrombolysis|OTHER: Standard medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pilates and Aerobic Exercises on Pain, Anxiety and QOL in PMS
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: OTHER: Pilates training|OTHER: Aerobic Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Self-Management Support Provided to Hypertension Patients Affected by the Earthquake Via Tele-Nursing on Patients' Treatment Compliance and Self-Care Management
Status: NOT_YET_RECRUITING
Conditions: With Tele-Nursing
Interventions: BEHAVIORAL: With Tele-Nursing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Triamcinolone Levels in Cochlear Perilymph, Lateral Canal and CSF
Status: COMPLETED
Conditions: Vestibular Schwannoma
Interventions: DRUG: Triamcinolone Acetonide 40mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Procedural Sedation Protocol Used for Dental Care Delivery in People With Mental Disability
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Care for Disabled
Interventions: DRUG: Midazolam Mylan|DRUG: Lorazepam Mylan|DRUG: Valium + Akineton + Dehydrobenzperidol + Atropine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LAGB Versus VBG: 7-Year Results
Status: COMPLETED
Conditions: Morbid Obesity|Bariatric Surgery|Vertical Banded Gastroplasty|Laparoscopic Adjustable Gastric Banding|Long Term Results
Interventions: PROCEDURE: Laparoscopic adjustable gastric banding|PROCEDURE: vertical banded gastroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Preventative and Therapeutical Effect of Ursodeoxycholic Acid(UDCA) to Short Bowel Syndrome Patients
Status: COMPLETED
Conditions: Short Bowel Syndrome
Interventions: DRUG: ursodeoxycholic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of a Novel Therapeutic Vaccine Against Hepatitis C Using Ad6NSmut and MVA-NSmut in Chronically Infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Ad6NSmut, MVA-NSmut
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal Epilepsy
Status: ENROLLING_BY_INVITATION
Conditions: Focal Epilepsy
Interventions: DRUG: Lamotrigine tablet|DRUG: Carbamazepine-Containing Product in Oral Dose Form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mild to Moderate Joint Pain in Patients With Chronic Plaque Psoriasis Receiving Efalizumab
Status: COMPLETED
Conditions: Arthritis|Arthralgia
Interventions: DRUG: Acetaminophen|DRUG: NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Biomechanics and Continuous IOP Monitoring Using Soft Contact Lenses in Glaucomatous Patients
Status: COMPLETED
Conditions: Open Angle Glaucoma With a Progressive Visual Field
Interventions: DEVICE: SENSIMED Triggerfish®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: c-CetuIRI Versus Ersecond-line Irinotecan s-IRI-CetuIRI
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Irinotecan|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Auricular Acupressure on the Management of Postoperative Nausea and Vomiting After Gynecological Laparoscopic Surgeries
Status: COMPLETED
Conditions: Laparoscopic Surgery|PONV|Auricular Acupressure
Interventions: OTHER: auricular acupressure|OTHER: sham auricular acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Treatment of COVID-19 Acute Respiratory Distress
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: COVI-MSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma|Glioblastoma|Glioblastoma Multiforme|GBM|Brain Cancer
Interventions: DRUG: VAL-083 (Dianhydrogalactitol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mirabegron and Tadalafil on Glucose Tolerance in Prediabetics
Status: RECRUITING
Conditions: Pre-diabetes|Obesity
Interventions: DRUG: Mirabegron 50 MG|DRUG: Tadalafil 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Dasatinib in Children and Adolescents With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (CML) or With Ph+ Leukemias Resistant or Intolerant to Imatinib
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STereotactic sAlvage Radiotherapy for Macroscopic Prostate Bed Recurrence After prostatectomy-a Prospective Observational Study
Status: UNKNOWN
Conditions: Prostate Cancer|Relapse
Interventions: OTHER: Stereotactic salvage radiotherapy for macroscopic prostate bed relapse
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Spinal Cord Stimulation for Diabetic Polyneuropathy
Status: WITHDRAWN
Conditions: Diabetic Polyneuropathy
Interventions: DEVICE: ANS Eon™ Implantable Pulse Generator (Permanent Implant)|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect on Migraine Frequency of Combined Anti-oxidant Therapy: The MIGRANT Study.
Status: UNKNOWN
Conditions: Migraine, Headaches
Interventions: DRUG: N-acetyl cysteine 600 mg, VitE 250 IU, VitC 500 mg tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Megaprosthetic Implants the Next Generation (MING)
Status: UNKNOWN
Conditions: Bone Neoplasm of Hip (Diagnosis)
Interventions: DEVICE: Megaprosthetic Implants the Next Generation (MING)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laronidase (Aldurazyme TM) Enzyme Replacement Therapy With Hematopoietic Stem Cell Transplant for Hurler Syndrome
Status: TERMINATED
Conditions: Mucopolysaccharidosis Type IH|MPS I|Hurler Syndrome
Interventions: DRUG: Laronidase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis (PSC)
Interventions: DRUG: Obeticholic Acid (OCA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nursing Care for Breathing Discomfort Among Mechanically Ventilated Patients
Status: UNKNOWN
Conditions: Dyspnea
Interventions: OTHER: visual analogue scale (VAS),Respiratory distress observational scale (RDOS) and other Nursing care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics With a New Oral Nicotine Replacement Product and Nicorette® Gum
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AGe-adapted Benefits of Envarsus Versus Twice-daily Tacrolimus ImmunosuppressioN druGs After Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplant Failure and Rejection
Interventions: DRUG: ENVARSUS|DRUG: Standard twice daily tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound and EMG Guided Botox Injection for the Treatment of Non-Relaxing Puborectalis Syndrome
Status: TERMINATED
Conditions: Non-relaxing Puborectalis Syndrome
Interventions: DRUG: botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: OTHER: Pre-operative exercise therapy and education|OTHER: Standardized pre-operative information session
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin and Maternal Neglect
Status: COMPLETED
Conditions: Maternal Behavior
Interventions: DRUG: Intranasal Oxytocin|DRUG: Placebo|PROCEDURE: Functional MRI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Anterior Approach Versus Direct Lateral Approach in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Coxarthrosis
Interventions: PROCEDURE: direct anterior approach|PROCEDURE: direct lateral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vestibular Rehabilitation for Chronic Central Vestibular Deficits: A Case Study
Status: COMPLETED
Conditions: Vestibular Disorder|Fall|Coordination and Balance Disturbances
Interventions: OTHER: Vestibular Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychological Intervention for Distress During HSCT
Status: COMPLETED
Conditions: Psychological Distress|Haematopoietic Stem Cell Transplantation|Bone Marrow Transplantation
Interventions: OTHER: Psychological preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE Patients
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Telitacicept|DRUG: Hydroxychloroquine|DRUG: Prednisone|DRUG: Methylprednisolone|DRUG: Cyclophosphamide|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Transition Program for Adolescents With Type 1 Diabetes in the Transition to Adulthood
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: A Person-Centred Transition Program to Empower Adolescents With Type 1 Diabetes in the Transition to Adulthood: the STEPSTONES-DIAB Project|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: INTEGRATED IMPACT ASSESSMENT a Telemedicine Program in the Care of Patients With Diabetes Mellitus Type 1 Intensive Treatment With Multiple Daily Injections.
Status: COMPLETED
Conditions: Metabolic Impact
Interventions: DEVICE: telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of A-101 Solution 40% in Subjects With Seborrheic Keratosis.
Status: COMPLETED
Conditions: Seborrheic Keratosis
Interventions: DRUG: A-101 Solution|OTHER: Vehicle Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
Status: COMPLETED
Conditions: Alzheimers Disease|Postoperative Delirium|Post Operative Cognitive Dysfunction
Interventions: DRUG: Total intravenous anesthesia with propofol|DRUG: General anesthesia with isoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Xeloda (Capecitabine) in Women With HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sorafenib + Paclitaxel + Carboplatin|DRUG: Placebo + Paclitaxel + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Assessment of a Novel Wedge Shape Implant Placed in Edentulous Narrow Ridges
Status: COMPLETED
Conditions: Surgical Technique|Implant Surface
Interventions: PROCEDURE: Bone Consumption|PROCEDURE: Bone expansion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thymus Transplantation Dose in DiGeorge #932
Status: COMPLETED
Conditions: DiGeorge Anomaly|DiGeorge Syndrome|Complete DiGeorge Anomaly|Complete DiGeorge Syndrome
Interventions: BIOLOGICAL: Cultured Thymus Tissue Implantation (CTTI)|OTHER: Cultured Thymus Tissue Implantation with Parathyroid Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Potentially Inappropriate Medication Prescribing for Older Patients in the ED
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: OTHER: EQUIPPED with Active Feedback|OTHER: EQUIPPED with Passive Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Endocrine Tumors of the Gastrointestinal Tract.
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: bevacizumab [Avastin]|DRUG: 5 FU|DRUG: Streptozotocin|DRUG: Xeloda
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Saroglitazar Magnesium for Treatment of Primary Biliary Cholangitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Biliary Cholangitis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma
Status: TERMINATED
Conditions: Transitional Cell Carcinoma|Bladder Carcinoma|Urothelial Carcinoma
Interventions: DRUG: Everolimus|DRUG: Everolimus|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib in Treating Patients With Metastatic Urothelial Cancer
Status: COMPLETED
Conditions: Distal Urethral Cancer|Proximal Urethral Cancer|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Urethral Cancer|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: DRUG: pazopanib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-Exercise vs General Physical Activity: Effect on Health-related Quality of Life
Status: COMPLETED
Conditions: Health-Related Quality of Life
Interventions: OTHER: Balance- training and home-exercise|OTHER: Balance-training and home-exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Kinematics for Subjects With Smith & Nephew Journey II BCS TKA, Journey II CR TKA, Or Journey II XR TKA
Status: COMPLETED
Conditions: Knee Osteoarthritis|Total Knee Arthroplasty|Knee
Interventions: DEVICE: Journey II Bi-Cruciate Stabilized TKA|DEVICE: Journey II Cruciate Retaining TKA|DEVICE: Journey II Bi-Cruciate Retaining TKA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thrombelastography Based Dosing of Enoxaparin
Status: COMPLETED
Conditions: Thromboembolic Complications
Interventions: DRUG: Enoxaparin dose adjusted Lovenox based on TEG|DRUG: Enoxaparin 30 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Alpha-1-Antitrypsin (AAT) in Steroid Refractory Acute Graft vs Host Disease
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: Alpha-1-Antitrypsin (AAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALRN-6924 and Paclitaxel in Treating Patients With Advanced, Metastatic, or Unresectable Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Estrogen Receptor Positive|HER2/Neu Negative|Metastatic Malignant Solid Neoplasm|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Recurrent Breast Carcinoma|TP53 wt Allele|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: MDM2/MDMX Inhibitor ALRN-6924|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies
Status: RECRUITING
Conditions: Costello Syndrome|Noonan Syndrome|Cardiofaciocutaneous Syndrome|Legius Syndrome|Capillary Arteriovenous Malformation Syndrome|RASopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pericardiotomy in Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation|Atrial Flutter|Cardiac Events
Interventions: PROCEDURE: Left Posterior Pericardiotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacogenomics Blood Sampling Protocol For Irinotecan/Fluorouracil/Leucovorin(CPT-11/FU/LV).
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microspheres in Preventing Lymphatic Fluid Collection After Surgery in Patients With Prostate Cancer
Status: TERMINATED
Conditions: Lymphocele|Prostate Cancer
Interventions: PROCEDURE: robot-assisted laparoscopic surgery|PROCEDURE: regional lymph node dissection|DEVICE: microsphere-mediated lymphocele prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Surgery in Elderly With Traumatic Acute SubDural Hematoma
Status: WITHDRAWN
Conditions: Intracranial Hemorrhages|Surgery
Interventions: OTHER: Early neurosurgical hematoma evacuation|OTHER: Conservative treatment (best medical management)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study on Safety and Tolerability of SAR425899 in Overweight to Obese Subjects and Type 2 Diabetes Mellitus Patients Not Requiring Anti-Diabetic Pharmacotherapy With an Optional 6-month Safety Extension Period
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SAR425899
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy
Status: RECRUITING
Conditions: Neurocognitive Impairment, Mild
Interventions: DRUG: Atorvastatin|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Effects of Intrathoracic Pressure Overshoot During Carbon Dioxide Insufflation in Thoracoscopic Surgery
Status: COMPLETED
Conditions: Esophageal Neoplasms
Interventions: DEVICE: Insufflation of carbon dioxide (CO2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL
Status: RECRUITING
Conditions: PTCL
Interventions: DRUG: Azacytidine|DRUG: Romidepsin|DRUG: Belinostat|DRUG: Pralatrexate|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Supplementation on Psoriasis Severity
Status: COMPLETED
Conditions: Psoriasis|Vitamin D Deficiency
Interventions: DRUG: 25-Hydroxyvitamin D|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Airway Interventions, During One Lung Ventilation, on Blood Oxygen Content
Status: UNKNOWN
Conditions: Thoracic, Diseases
Interventions: PROCEDURE: RM + Positive End Expiratory Pressure|PROCEDURE: Continuous Positive Airway Pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study in Patients With Acne Vulgaris.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: ADPS topical product|DRUG: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Universal Electronic Health Record-based IMPROVE DD VTE Risk Assessment Model for the Prevention of Thromboembolism in Hospitalized Medically Ill Patients
Status: COMPLETED
Conditions: Venous Thromboembolism|Arterial Thromboembolism
Interventions: OTHER: IMPROVE DD VTE Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose, Bioequivalence Study of Generic Alfuzosin Hydrochloride 10 mg Prolonged-release Tablets Under Fed Conditions
Status: NOT_YET_RECRUITING
Conditions: Healthy Vollunteer
Interventions: DRUG: Alfuzosin Hydrochloride 10 mg|DRUG: Xatral® XL 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Effectiveness and Safety Study of Chinese Herbal Medicine for Functional Constipation
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders|Constipation
Interventions: DRUG: MaZiRenWan (MZRW)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of GSK Measles-mumps-rubella-varicella (MMRV) Vaccine Versus PriorixTM
Status: COMPLETED
Conditions: Varicella|Rubella|Mumps|Measles
Interventions: BIOLOGICAL: GSK Biological's investigational MMRV vaccine 208136|BIOLOGICAL: Priorix™|BIOLOGICAL: Varilrix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Assess the Safety and PK of OMN6 in HABP or VABP Caused by Acinetobacter Baumannii Complex
Status: RECRUITING
Conditions: Hospital-acquired Bacterial Pneumonia|Ventilator-associated Bacterial Pneumonia
Interventions: DRUG: OMN6|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of Low Wattage and High Wattage E-Cigarettes
Status: COMPLETED
Conditions: Smoking, Cigarette|Smoking, Tobacco|Nicotine Dependence|Exposure to Toxic Agent
Interventions: BEHAVIORAL: Low wattage E cigarette device|BEHAVIORAL: High wattage E cigarette device|BEHAVIORAL: Usual brand cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Epidural Dexamethasone on Labor Analgesia
Status: UNKNOWN
Conditions: Labor
Interventions: DRUG: Levobupivacaine|DRUG: Dexamethasone and levobupivacaine|DRUG: Levobupivacaine and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Heart Rate Variability Biofeedback With In-patient Pregnant Women
Status: TERMINATED
Conditions: Maternal Stress|Maternal Anxiety|Maternal Health Services
Interventions: BEHAVIORAL: Heart Rate Variability Biofeedback Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult
Status: NOT_YET_RECRUITING
Conditions: Acute Myeloid Leukemia, Adult
Interventions: PROCEDURE: DEC3-VEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study Comparing the Liraglutide Injection (RD12014) and Victoza® in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Liraglutide injection,RD12014|DRUG: Liraglutide injection,Victoza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Alogliptin|DRUG: Acarbose|DRUG: Metformin|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Web-enabled Integrated Care Pathway (ICP) for Addressing Multiple Modifiable Risk Factors as a Part of Smoking Cessation Treatment in Primary Care Settings.
Status: COMPLETED
Conditions: Physical Activity|Fruits and Vegetable Consumption|Smoking Cessation
Interventions: BEHAVIORAL: Brief physical activity and diet intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Qishe Pill for Cervical Radiculopathy
Status: UNKNOWN
Conditions: Cervical Radiculopathy
Interventions: DRUG: Qishe Pill|DRUG: Qishe Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Effectiveness of a Type of Interleukin-2 Plus Zidovudine Plus Thymosin in HIV-Positive Patients With and Without Symptoms of Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Thymalfasin|DRUG: Interleukin-2, Polyethylene Glycolated|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: MyVoice:CF Decision Aid for Women With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Contraception|Physician-Patient Relations|Pregnancy Complications
Interventions: OTHER: MyVoice:CF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparative Effects of Clamshell Technique With EMS vs CTin Iliotibial Band Tightness for Pain and Function
Status: ACTIVE_NOT_RECRUITING
Conditions: Tibial Muscular Dystrophy
Interventions: DIAGNOSTIC_TEST: Clamshell exercises with Electrical Muscle Stimulation (CT + EMS)|OTHER: Conservative Treatment (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of bb2121 (Ide-cel) Combinations in Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BB2121|DRUG: CC-220|DRUG: BMS-986405
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: LY01005 3.6 mg|DRUG: ZOLADEX® 3.6 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Effect of a CANDIDA Mouthwash, Containing the Curolox™ Peptide
Status: WITHDRAWN
Conditions: Erosion of Teeth, Unspecified
Interventions: DEVICE: Candida Mouthwash with Curolox™ Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Wound Healing With Hyaluronic Acid After Alveolar Ridge Preservation
Status: COMPLETED
Conditions: Healing Wound
Interventions: DEVICE: Gengigel Forte©
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a-Interferon With Adriamycin, Bleomycin, Velban, and Dacarbazine (ABVD) With Hodgkin's Disease
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Interferon-2A|DRUG: Adriamycin|DRUG: Bleomycin|DRUG: Velban|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Acupuncture Improves Constipation for Critical Care Nurses During the COVlD-19 Pandemic
Status: UNKNOWN
Conditions: Nurse
Interventions: DEVICE: Acupoint stimulation with low energy laser (Erger laser pen)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Posture Correction Girdle for Adolescent With Early Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Posture Correction Girdle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Medication Used to Stimulate Ovulation
Status: UNKNOWN
Conditions: IVF Cycle|Ovarian Stimulation|Egg Retrieval|Pregnancy|Miscarriages|Ovarian Hyperstimulation
Interventions: DRUG: Ovulation induction with hCG and Lupron (GnRH agonist)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Methylprednisolone or Ibuprofen on Efficacy of Nerve Blocks With Symptomatic Irreversible Pulpitis
Status: TERMINATED
Conditions: Irreversible Pulpitis
Interventions: DRUG: Ibuprofen|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Post-market, Observational Registry With the easyEndoTM Universal Linear Cutting Stapler in Laparoscopic Bariatric Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Roux-en-Y Gastric Bypass|Gastrectomy|Mini Gastric Bypass
Interventions: DEVICE: easyEndoTM Universal Linear Cutting Stapler and reloads (Ezisurg Medical)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Encapsulated Allogeneic MPS-1 Therapy
Status: WITHDRAWN
Conditions: MPS I|MPS1-S|MPS1-HS
Interventions: COMBINATION_PRODUCT: SIG-005 (hIDUA Producing Spheres)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis
Status: RECRUITING
Conditions: Primary Biliary Cholangitis|PBC
Interventions: DRUG: Volixibat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic and Strength Training With Caloric Restriction on Insulin Resistance in Obese Premenopausal Women
Status: COMPLETED
Conditions: Insulin Resistance Syndrome
Interventions: OTHER: Resistance exercise|OTHER: Aerobic exercise|DIETARY_SUPPLEMENT: diet restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety in Male Subjects With Premature Ejaculation
Status: TERMINATED
Conditions: Premature Ejaculation
Interventions: DRUG: Tramadol Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: