pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Pharmacokinetic Study on Co-administration of Tamiflu (Oseltamivir) and Rimantadine in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: oseltamivir [Tamiflu]|DRUG: rimantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Prophylactic Corticosteroid to Prevent COVID-19 Cytokine Storm
Status: UNKNOWN
Conditions: Covid-19
Interventions: DRUG: MethylPREDNISolone 80 Mg/mL Injectable Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Balanced Propofol Sedation Versus Propofol Alone Sedation in Therapeutic Endoscopic Retrograde Cholangiopancreatography (ERCP)
Status: UNKNOWN
Conditions: Conscious Sedation Failure During Procedure
Interventions: DRUG: Propofol|DRUG: BPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategy for Relapsed/Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma|Refractory Hodgkin Lymphoma|Relapsed Hodgkin's Disease, Adult
Interventions: DRUG: Brentuximab Vedotin 50 MG [Adcetris]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5Fluorouracil|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Aeroquin Versus Tobramycin Inhalation Solution (TIS) in Cystic Fibrosis (CF) Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: MP-376 (Levofloxacin Solution for Inhalation)|DRUG: TIS (Tobramycin Inhalation Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety/Tolerance Study of PPI-2458 in Subjects With Non-Hodgkin's Lymphoma and Solid Tumors
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma,|Solid Tumors
Interventions: DRUG: PPI-2458
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Antidepressant Effect of Right Temporal Low Frequency rTMS Compared to Sham
Status: TERMINATED
Conditions: Depressive Disorder
Interventions: PROCEDURE: right temporal low frequency (1 hz) rTMS|PROCEDURE: Sham-rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depression and Pain Perseverance Through Empowered Recovery Intervention
Status: COMPLETED
Conditions: Pain|Depressive Symptoms|Frailty|Aging
Interventions: BEHAVIORAL: DAPPER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefit of the Use of Autologous Glue Prepared With RegenKit®-Surgery Device in Abdominoplasty
Status: UNKNOWN
Conditions: Abdominoplasty
Interventions: DEVICE: Autologous glue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study for the Safety and the Pharmacokinetics of DWJ1543 in Healthy Adult Volunteers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: DWJ1543|DRUG: DWC202216
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
Status: COMPLETED
Conditions: Post Induction Hypotension
Interventions: DRUG: Ringer acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infection
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H0731|DRUG: ETV|BIOLOGICAL: Peg-IFNα
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of HRS-7085 Tablet in Healthy Participants With and Without Food Effect.
Status: COMPLETED
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: HRS-7085 tablets|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care Online Emotion-regulation Treatment
Status: COMPLETED
Conditions: Mental Health Issue
Interventions: BEHAVIORAL: Therapist-supported digitally delivered transdiagnostic emotion regulation treatment|BEHAVIORAL: Therapist-supported digitally delivered supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib (BMS-354825) in Patients With Accelerated Phase Chronic Myeloid Leukemia
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Energy Availability and Pituitary Function (LEAP Study)
Status: RECRUITING
Conditions: Hypogonadotropic Hypogonadism
Interventions: BEHAVIORAL: 5-day controlled metabolic dietary intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Efficacy and Safety of the Postoperative Analgesia Methods
Status: UNKNOWN
Conditions: Supratentorial Neoplasms
Interventions: DRUG: Morphine|DRUG: Dexketoprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anemia Study in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Blood Pressure (ASCEND-BP)
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: Daprodustat|DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Colorectal Cancer|Cholangiocarcinoma|Bladder Cancer|Ovarian Cancer|Gastric Cancer|Palpable Subcutaneous Malignant Lesions|Renal Cell Carcinoma|Melanoma|Epithelial Ovarian Cancer|Primary Peritoneal Cancer|Fallopian Tube Cancer
Interventions: BIOLOGICAL: TRK-950|BIOLOGICAL: TRK-950|BIOLOGICAL: TRK-950|DRUG: Irinotecan|DRUG: Leucovorin|DRUG: 5-FU|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Ramucirumab|DRUG: Paclitaxel|DRUG: Nivolumab|DRUG: Pembrolizumab|DRUG: Imiquimod Cream|DRUG: Bevacizumab|DRUG: PLD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebrovascular EveNts in Patients Undergoing TranscathetER Aortic Valve Implantation With Balloon-expandable Valves Versus Self-expandable Valves.
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: transcatheter aortic valve implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gingival Crevicular Fluid Vaspin and Omentin Levels in Type 2 Diabetic Patients With Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis|Diabetes Mellitus
Interventions: OTHER: gingival crevicular fluid|OTHER: non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tislelizumab in Combination With Chemotherapy Versus Chemotherapy in Advanced Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of XL114 in Subjects With Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Non-Hodgkin's Lymphoma (NHL)|Activated B-Cell Type Diffuse Large B-Cell Lymphoma (ABC-DLBCL)|Mantle Cell Lymphoma (MCL)|Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: XL114
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of KIACTA in Preventing Renal Function Decline in AA Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: KIACTA (eprodisate disodium)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Automated Adjustment of Inspired Oxygen to Maintaining Regional Cerebral Oxygenation in Preterm Infants on Respiratory Support
Status: UNKNOWN
Conditions: Cerebrovascular Circulation|Premature Infants
Interventions: DEVICE: Automated FiO2 adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of 'Pelubiprofen Controlled Released Tab.' in Acute Traumatic Injury
Status: UNKNOWN
Conditions: Acute Traumatic Injury
Interventions: DRUG: pelubiprofen 45mg|DRUG: pelubiprofen placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients
Status: COMPLETED
Conditions: Schizophrenia, Undifferentiated Type
Interventions: OTHER: Imagery|GENETIC: pharmacogenetic sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Nalmefene hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Beliefs, Glycemic Control, and Preventing Cognitive Decline in African Americans With Diabetes and Mild Cognitive Impairment: A Randomized Clinical Trial
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Diabetes
Interventions: BEHAVIORAL: Diabetes Regulation for Eyesight and Memory|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Uproleselan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual Reality in the Treatment of Pelvic Floor Dysfunction in Women With Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: OTHER: Virtual reality|OTHER: Neuromodulation of the tibialis posterior nerve|OTHER: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY
Status: COMPLETED
Conditions: Klinefelter Syndrome
Interventions: DRUG: Testosterone Cypionate 200 Milligram/Milliliter Injectable Solution|DRUG: Placebo injectable saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Cimzia in Crohn's Patients
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: certolizumab pegol|BIOLOGICAL: certolizumab pegol|BIOLOGICAL: certolizumab pegol|BIOLOGICAL: certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraocular Pressure Control Following One Site Versus Two Site Combined Phacoemulsification/IOL And Trabeculectomy
Status: COMPLETED
Conditions: Glaucoma|Cataracts
Interventions: PROCEDURE: 2 Site procedure- Phacoemulsification/IOL and Trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Combined With Radiation Therapy in Treating Patients Who Have Stage II or Stage III Cancer of the Esophagus
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: fluorouracil|DRUG: hydroxyurea|DRUG: paclitaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Study of Epofolate (BMS-753493) in Subjects With Advanced Cancer (Schedule 1)
Status: TERMINATED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Epofolate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)
Status: RECRUITING
Conditions: Mechanical Ventilation Complication|Pulmonary Edema
Interventions: PROCEDURE: Spontaneous breathing trial
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hysteroscopic "Hot Knife" and "Cold Knife" in the Treatment of the Intrauterine Adhesion
Status: UNKNOWN
Conditions: Intrauterine Adhesion
Interventions: PROCEDURE: cold knife|PROCEDURE: hot knife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Arm Objective Performance Criteria Trial For Intracranial Thrombus Aspiration Catheter
Status: UNKNOWN
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: Thrombus Aspiration Catheter(Ton-bridgeMT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Overcoming Insomnia: Impact on Sleep, Health and Work of Online CBT-I
Status: UNKNOWN
Conditions: Insomnia
Interventions: BEHAVIORAL: CBT for insomnia (CBT-I)|BEHAVIORAL: Psycho-Education about Sleep (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: WVE-210201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterize the Abuse Liability of Intravenous Oxycodone Alone or in Combination With Intravenous Naltrexone in Healthy, Non-Dependent, Recreational Opioid Users
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Oxycodone + Naltrexone|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Aducanumab (BIIB037)|DRUG: Aducanumab (BIIB037)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrin Glue for Perianal Fistulas in Crohn's Disease: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: PROCEDURE: Fibrin glue injection in fistula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Needle Electrolysis Versus Surgery in the Treatment of Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: PNE|PROCEDURE: Surgery for CTS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Using Triclosan-antibacterial Sutures on the Incidence of Surgical Site Infection
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: OTHER: Vicryl Plus|OTHER: Vicryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Regurgitation|Mitral Disease
Interventions: DEVICE: Edwards SAPIEN M3 System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Transpyloric Stenting as a Predictor for G-POEM for Refractory Gastroparesis
Status: RECRUITING
Conditions: Gastroparesis
Interventions: DEVICE: Transpyloric stent|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phage II Trial of Stathmin as Predictive Biomarker for TPF Induction Chemotherapy in OSCC
Status: RECRUITING
Conditions: Neoplasm Neck
Interventions: DRUG: docetaxel, cisplatin and 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SPY001-001 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: SPY001-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: PROCEDURE: T-Cell replete haplo-transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the "Tecaretherapy" in Patients With Lateral Elbow Tendinopathy
Status: TERMINATED
Conditions: Tendinopathy
Interventions: OTHER: Active Tecaretherapy|OTHER: Inactive Tecaretherapy|OTHER: CPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Effectiveness of Beltavac® Polymerized With House Dust Mites
Status: COMPLETED
Conditions: Rhinoconjunctivitis With or Without Allergic Asthma
Interventions: BIOLOGICAL: Beltavac® Polymerized with house dust mites
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Activity, Adiposity, and Appetite in Adolescents 2 Intervention
Status: RECRUITING
Conditions: Obesity|Energy Balance|Appetite|Metabolism|Insulin Sensitivity
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Newsletter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lapatinib in Combination With Radiation Therapy in Patients With Brain Metastases From HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Brain Metastases
Interventions: DRUG: Lapatinib|PROCEDURE: Whole Brain Radiation|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Iron Bioavailability From Iron Chlorophyllin
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: SIC|DIETARY_SUPPLEMENT: SIC + AA combined|DIETARY_SUPPLEMENT: FeSO4|DIETARY_SUPPLEMENT: FeSO4 + AA combined|OTHER: EP + FeSO4 combined|OTHER: EP + FeSO4 + AA combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aripiprazole Once-monthly Versus Paliperidone Palmitate in Adult Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole and aripiprazole once-monthly|DRUG: Paliperidone and paliperidone palmitate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analyse Of Early Skın To Skın Contact's Impact Upon Maternal-Infant Bondıng And Perceptıon Of Traumatıc Bırth
Status: COMPLETED
Conditions: Postpartum
Interventions: BEHAVIORAL: skin-to-skin contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Status: COMPLETED
Conditions: Leukemia, Acute Lymphoblastic|Acute Myeloid Leukemia|Mixed-Lineage Acute Leukemias
Interventions: PROCEDURE: Allogeneic stem cell transplantation|DRUG: Fludarabine monophosphate|DRUG: Busulfan|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pramlintide on Endogenous Production of Very-low-density-lipoprotein (VLDL)-Triglyceride and Glucose in the Post Prandial State in T2DM
Status: WITHDRAWN
Conditions: Type 2 Diabetes
Interventions: DRUG: Pramlintide acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Electrical Stimulation on Glucose Variability in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DEVICE: NMES|DEVICE: NMES-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients With Metastatic Cancer in Response After 6 Months of Standard IO
Status: RECRUITING
Conditions: Lung Cancer Metastatic|Renal Cell Carcinoma|Head and Neck Cancer|Bladder Cancer|Triple Negative Breast Cancer|Merkel Cell Carcinoma|Hepatocellular Carcinoma|Melanoma
Interventions: DRUG: Reduced dose intensity of IO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options
Status: COMPLETED
Conditions: Generalized Pustular Psoriasis
Interventions: DRUG: spesolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for the Assessment of Delayed Antibiotic Treatment in Pediatric (DAP-Pediatrics)
Status: COMPLETED
Conditions: Rhinosinusitis|Acute Bronchitis|Acute Otitis Media|Pharyngotonsillitis
Interventions: OTHER: Antibiotic prescription strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Multiple Sclerosis, Progressive|Cognition - Other|Memory Impairment
Interventions: BEHAVIORAL: Memory retraining exercises|BEHAVIORAL: Placebo control memory exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Digital Health Tool for Insulin Titration (DHIT) Individuals With Type 2 Diabetes: A Prospective Outcomes Study With a Retrospective Control Group
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: Basal Insulin Titration Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Balance, Pharmacokinetics and Metabolism Study of Alisertib
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphoma
Interventions: DRUG: [^14C]-alisertib|DRUG: alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients
Status: TERMINATED
Conditions: Sedation
Interventions: DRUG: Ketamine|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
Status: COMPLETED
Conditions: Oropharyngeal Dysphagia|Stroke
Interventions: DEVICE: Cerebellar TMS|DEVICE: Sham cerebellar TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study, Called ROCURS, to Learn About COVID-19 Related Outcomes in People With Cancer Who Are Treated With Tyrosine Kinase Inhibitors (TKIs) Including Regorafenib or Sorafenib
Status: COMPLETED
Conditions: Malignant Solid Tumors|Coronavirus Disease 2019 (COVID-19)|SARS-CoV-2 Infection
Interventions: DRUG: Non-TKIs|DRUG: Other TKIs|DRUG: Regorafenib (Stivarga, BAY73- 4506)|DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Therapy Effect of Azathioprine Initial or 14 Weeks After Combined With Infliximab on CD
Status: UNKNOWN
Conditions: Crohn Disease
Interventions: DRUG: infliximab and azathioprine combination at week 0|DRUG: infliximab and azathioprine combination at week 14
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Culturelle in the Prophylaxis of Infection and Diarrhea
Status: TERMINATED
Conditions: Pediatric Burns
Interventions: DIETARY_SUPPLEMENT: Culturelle|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Characterizing Adipose Tissue Leukocytes by Flow Cytometry/Microscopy in Lean, Obese and Psoriatic Subjects
Status: TERMINATED
Conditions: Psoriasis|Obesity
Interventions: PROCEDURE: Adipose tissue biopsy (fat biopsy)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Craniosacral Therapy on Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Craniosacral Therapy|PROCEDURE: Sham Craniosacral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Anti-Depressant for Chronic Obstructive Pulmonary Disease (SAD-COPD)
Status: TERMINATED
Conditions: COPD|Anxiety|Depression|Stress|Interstitial Lung Disease
Interventions: DRUG: Sertraline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rhomboid Intercostal Plane Block vs Local Anesthetic Infilteration for Postoperative Analgesia After Thoracoscopic Surgery
Status: UNKNOWN
Conditions: Anesthesia
Interventions: OTHER: Rhomboid intercostal plane block or Local anesthetic infiltration of 0.25% Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cervicothoracic Junction Mobilization Versus Muscle Energy Technique in Chronic Neck Pain
Status: COMPLETED
Conditions: Chronic Mechanical Neck Pain
Interventions: OTHER: cervicothoracic junction mobilization in form of Maitland mobilization|OTHER: autogenic muscle Energy Technique|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lithium Effects on Reward Processing and Reappraisal in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lithium|OTHER: Placebo - Rayotabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease
Status: RECRUITING
Conditions: Parkinson Disease|Gait Disorders, Neurologic|Disease Progression|Subthalamic Nucleus|Accidental Fall|Deep Brain Stimulation
Interventions: DEVICE: High-Frequency-Only Stimulation|DEVICE: Low-Frequency-Only Stimulation|DEVICE: Alternating, 50 sec High-Frequency, 10 sec Low-Frequency Stimulation|DEVICE: Alternating, 50 sec High-Frequency, 50 sec Low-Frequency Stimulation|DEVICE: Alternating, 10 sec High-Frequency, 50 sec Low-Frequency Stimulation|DEVICE: Alternating, 10 sec High-Frequency, 10 sec Low-Frequency Stimulation|DRUG: OFF Dopaminergic Medication|DRUG: ON Dopaminergic Medication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microdose and First-In-Human (FIH) Study of Recombinant Human Placental Alkaline Phosphatase (hRESCAP)
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: hRESCAP|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Resistance Training and Blood Flow Restriction
Status: COMPLETED
Conditions: Blood Flow Restriction and Low-Intensity Resistance Training
Interventions: DEVICE: Blood Flow Restriction Cuffs|OTHER: Low-Intensity Resistance Training|OTHER: High-Intensity Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and Mouth
Status: COMPLETED
Conditions: Herpes Simplex
Interventions: DRUG: Acyclovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Efficacy Between Rehabilitation Therapy and Stem Cells Transplantation in Patients With SCI in China
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: BIOLOGICAL: cell therapy|OTHER: rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lao Zinc Study: Effects of Two Forms of Daily Preventive Zinc Versus Therapeutic Zinc Supplementation
Status: COMPLETED
Conditions: Diarrhea
Interventions: DIETARY_SUPPLEMENT: MNP|DIETARY_SUPPLEMENT: preventive zinc supplement|DIETARY_SUPPLEMENT: therapeutic zinc supplement|DIETARY_SUPPLEMENT: preventive placebo supplement|DIETARY_SUPPLEMENT: therapeutic placebo supplement|DIETARY_SUPPLEMENT: placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Airway Clearance Efficacy of Electro Flo 5000 and the G5 Flimm-Fighter in Patients With CF
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: Electro-Flo Intervention|DEVICE: G5 Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
Status: RECRUITING
Conditions: Myelofibrosis|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome|Myeloproliferative Neoplasm|Relapsed or Refractory Primary Myelofibrosis|Secondary Myelofibrosis (Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis)|ET (Essential Thrombocythemia)
Interventions: DRUG: INCB057643|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopy-Assisted Surgery for Carcinoma of the Low Rectum
Status: UNKNOWN
Conditions: Rectal Carcinoma
Interventions: PROCEDURE: laparoscopic-assisted rectal resection|PROCEDURE: conventional open rectal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of XL147 (SAR245408), in Combination With Paclitaxel and Carboplatin in Adults With Solid Tumors
Status: COMPLETED
Conditions: Cancer|Non-Small Cell Lung Cancer|Endometrial Carcinoma|Ovarian Carcinoma
Interventions: DRUG: XL147 (SAR245408),|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reproductive Outcome After Sperm Selection for Intracytoplasmic Sperm Injection (ICSI) Using Zona Pellucida Proteins
Status: ENROLLING_BY_INVITATION
Conditions: Infertility, Male
Interventions: OTHER: Zona pellucida sperm selection|OTHER: Conventional sperm selection|OTHER: Intracytoplasmic Sperm Injection (ICSI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Uterine Closure Techniques and Cesarean Scar Defect Risk
Status: COMPLETED
Conditions: Cesarean Section Complications|Scar; Deformity
Interventions: PROCEDURE: Uterine closure during Cesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sildenafil and Stroke Recovery
Status: TERMINATED
Conditions: Stroke
Interventions: DRUG: sildenafil citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Nanoparticle Thermoablation-Retention and Maintenance in the Prostate:A Phase 0 Study in Men
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: Magnetic Nanoparticle Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Carfilzomib in Patients With Relapsed Acute Myeloid or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Carfilzomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery
Status: RECRUITING
Conditions: Bariatric Surgery Candidate
Interventions: OTHER: Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals|OTHER: Standard Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance-based Group Intervention for Binge Eating
Status: COMPLETED
Conditions: Binge-Eating Disorder
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Brief MOVE-II control group intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD1603: A Crossover Study to Evaluate the Exposure to "Tar" and Nicotine From 100s Menthol Cigarette Products
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: PD21871AA|OTHER: PD21872AA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adjuvant Chemoradiotherapy Versus Chemotherapy for Pancreatic Cancer (ADJUPANC)
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: COMBINATION_PRODUCT: Adjuvant chemoradiotherapy|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Investigating EMDR for Suicidal Ideation
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Eye Movement Desensitization and Reprocessing (EMDR)|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Aggression|Irritability
Interventions: DRUG: Transdermal nicotine|OTHER: Transdermal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium|DEVICE: HandiHaler|DEVICE: Respimat SMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: GEN-001 Plus Pembrolizumab for Patients With Advanced Refractory Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: GEN-001|DRUG: Pembrolizumab|DRUG: mFOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tandem Autologous- Nonmyeloablative Allogeneic Transplant for Newly Diagnosed Multiple Myeloma (Trapianto Tandem Autologo-Allogenico Non Mieloablativo Nel Mieloma Alla Diagnosi)
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: This Study Compared an in Home Asthma Management Program Provided by Nurses or Respiratory Therapist
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: In-home asthma management program (AMP) provided by nurses|BEHAVIORAL: In-home asthma management program (AMP) provided by respiratory therapists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Tanespimycin, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: gemcitabine hydrochloride|DRUG: tanespimycin|DRUG: cisplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docosahexaenoic Acid in the Treatment of Autism
Status: COMPLETED
Conditions: Autism
Interventions: DIETARY_SUPPLEMENT: docosahexaenoic acid (DHA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suturing Through-the-scope System Used for Prophylactic Closure of Colonic Post-ESD Defects
Status: NOT_YET_RECRUITING
Conditions: Precancerous Lesion of Colon
Interventions: DEVICE: TTS suturing system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rutgers Pilot for Dental Health Care Worker SARS-CoV-2 Testing
Status: COMPLETED
Conditions: SARS-CoV2 Infection
Interventions: DEVICE: Testing for SARS CoV2 Antigen and Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of Two Different Strengths of the Inactivated COVID-19 Vaccine ERUCOV-VAC
Status: COMPLETED
Conditions: COVID-19 Vaccine
Interventions: BIOLOGICAL: ERUCOV-VAC|OTHER: Placebo Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Trial of Upfront Radiotherapy Plus Almonertinib for Epidermal Growth Factor Receptor(EGFR)-Mutant Non-small-cell Lung Cancer(NSCLC) Patients With Brain Metastases
Status: UNKNOWN
Conditions: EGFR Positive Non-small Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Almonertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection and Prevention of Concussive Injuries With Smart Technology.
Status: UNKNOWN
Conditions: Concussion|Head Injury Trauma
Interventions: DEVICE: Modern microelectrical mechanical systems (MEMS) head-impact sensors|OTHER: Virtual Reality (VR) Goggle Use with consistent timing of Conditioned Stimulus and Unconditioned Stimulus|OTHER: Virtual Reality (VR) Goggle Use with inconsistent timing of Conditioned Stimulus and Unconditioned Stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: White Test in Intra-operative Detection of Donor Biliary Leak in LDLTx.
Status: COMPLETED
Conditions: Bile Leak
Interventions: PROCEDURE: The White test uses fat emulsion (SMOFLIPID), for localization of bile leakage.|PROCEDURE: Saline test (routine test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mechanistic Randomized Controlled Trial (RCT) of Mesalazine in Symptomatic Diverticular Disease
Status: COMPLETED
Conditions: Diverticulosis, Colonic
Interventions: DEVICE: Mesalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bacopa Monnieri on Working Memory and Cognitive Processing in Student
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Bacopa Monnieri 300 mg/day|DIETARY_SUPPLEMENT: Bacopa Monnieri 600 mg/day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV (vCP205) and HIV-1 SF-2 rgp120 in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Selectively Modulating Pathophysiological Biomaker to Improve Freezing of Gait in Parkinson' s Disease by Adaptive Subthalamic Stimulation
Status: UNKNOWN
Conditions: Freezing of Gait|Parkinson Disease
Interventions: DEVICE: Neuro Omega
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-P16-093 and 18F-FDG PET/CT Imaging in the Same Group of Clear Cell Renal Cell Carcinoma Patients
Status: COMPLETED
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: 68Ga-P16-093|DRUG: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC