pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness of Audiovisual Versus Written Postoperative Instructions for Patients Undergoing Minor Hand Procedures
Status: NOT_YET_RECRUITING
Conditions: Carpal Tunnel Syndrome|Hand Cyst Ganglion|Trigger Finger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Estrogen and Perimenopausal Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major|Menopause
Interventions: DRUG: Estrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vestibular Stimulation on Motor Proficiency and Balance Among Children With Down Syndrome
Status: COMPLETED
Conditions: Vestibular System Disorder
Interventions: OTHER: Vestibular stimulation|OTHER: General strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT）
Status: COMPLETED
Conditions: Cirrhosis|Splenectomy; Status|Venous Thrombosis|Hypertension, Portal
Interventions: DRUG: Apixaban|DRUG: Warfarin|DRUG: Aspirin|DRUG: Dipyridamole|DRUG: Low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Repeat Treatment With PurTox® Botulinum Toxin Type A for Frown Lines Between the Eyebrows
Status: COMPLETED
Conditions: Glabellar Rhytides|Frown Lines Between the Eyebrows
Interventions: DRUG: Mentor Purified Toxin Botulinum Toxin Type A|DRUG: Preservative-free Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Treatment Methods Effect on Upper Extremity Spasticity and Decreased Functionality After Stroke
Status: COMPLETED
Conditions: Stroke|Spasticity as Sequela of Stroke|Limitation, Mobility
Interventions: OTHER: Vibration|OTHER: Modified Constraint-İnduced Movement Therapy|OTHER: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Eniluracil, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: ethynyluracil|DRUG: fluorouracil|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Autologous Platelet-rich Plasma in the Treatment of Persistent Epithelial Defects
Status: RECRUITING
Conditions: Persistent Epithelial Defect
Interventions: COMBINATION_PRODUCT: PRP plus BCL|COMBINATION_PRODUCT: BCL plus PFL|COMBINATION_PRODUCT: Eye patch plus ocular lubricant ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RC Repair Versus Subacromial Balloon Spacer in Older Adults
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: PROCEDURE: Subacromial spacer implantation|PROCEDURE: Rotator cuff repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Colistin Inhalation on Ventilator Associated Pneumonia
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: Colistin|DRUG: Carbapenem + Aminoglycoside/ Quinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation Study of Cortical Excitability as Marker of Antidepressant Response: EXCIPSY Study
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DEVICE: Measurements of markers of cortical excitability by TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Casein Phosphopeptide--amorphous Calcium Phosphate on Human Enamel Subjected to in Vivo Acid Attacks
Status: COMPLETED
Conditions: Dental Erosion
Interventions: DRUG: CPP-ACP|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorders
Interventions: DRUG: Eszopiclone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy
Status: COMPLETED
Conditions: Hip Disease
Interventions: DRUG: Bupivacaine + dexamethasone|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-arm Pilot Study of First-line Treatment With Carbognilumab Combined With Chemotherapy in Patients With STK11-mutated Advanced or Postoperative Recurrent Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Malignant Head and Neck Tumors
Interventions: DRUG: lithium-containing mouthwash|DRUG: Plcacebo mouthwash|DRUG: lithium-containing mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NEUROCUPLE™ in TKA Patients
Status: NOT_YET_RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: NEUROCUPLE™ Patch|DEVICE: Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Nerve Block vs Spinal Anesthesia in Hip Surgery
Status: COMPLETED
Conditions: Hip Arthroplasty
Interventions: PROCEDURE: Peripheral nerve block|PROCEDURE: Spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bosentan for Severe Mitral Valve Dysfunction
Status: UNKNOWN
Conditions: SECONDARY PULMONARY HYPERTENSION|MITRAL STENOSIS|CHILDHOOD RHEUMATOID FEVER|CONGESTIVE HEART FAILURE
Interventions: DRUG: BOSENTAN
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Accuracy of the ActiSight Needle Guidance System in Percutaneous Chest Aspiration and Biopsy
Status: COMPLETED
Conditions: Biopsy
Interventions: DEVICE: Biopsy needle guidance system (ActiSight™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Aerobic Exercise for Treating Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease, Late Onset
Interventions: BEHAVIORAL: Cycling exercise|BEHAVIORAL: Range of motion/stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failure
Status: TERMINATED
Conditions: Diastolic Heart Failure
Interventions: DRUG: Eplerenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Life Improvement Following Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Depression
Interventions: BEHAVIORAL: In-person Cognitive Behavioral Therapy|BEHAVIORAL: Telephone Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
Status: RECRUITING
Conditions: Solid Malignancy Located in the Head and Neck|Cancer|Carotid Stenosis|Atherosclerosis of Artery|Hodgkin Lymphoma, Adult|Non Hodgkin Lymphoma|HLH|Cardiac Sarcoidosis|Sarcoidosis
Interventions: DRUG: 68GaNOTA-Anti-MMR-VHH2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bipolar vs Monopolar Transurethral Resection of the Prostate (TURP)
Status: COMPLETED
Conditions: BPH|Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Bipolar Transurethral Resection of the Prostate|PROCEDURE: Monopolar Transurethral Resection of the Prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Air-polishing With Erythritol During Orthodontic Tretament
Status: RECRUITING
Conditions: Inflammation Gum|White Spot Lesion
Interventions: DEVICE: Ultrasonic scaler|DEVICE: Air-Flow Prophylaxis Master
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Investigation of Peginterferon Alfa-2a on the RFS of the Subjects With HCC Who Have Been Treated by Resection
Status: UNKNOWN
Conditions: Chronic Hepatitis b|Hepatic Carcinoma
Interventions: DRUG: ETV；TDF；ADV|DRUG: Peginterferon Alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Study of Cementless vs Cemented UKA
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: Engage Partial Knee|DEVICE: Engage Partial Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Efficacy and Tolerability of Quetiapine XR and Amitriptyline in the Treatment of Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: amitriptyline|DRUG: quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed/Refractory Peripheral T-cell Lymphoma
Interventions: DRUG: Tolinapant|DRUG: Decitabine + Cedazuridine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ColdZyme® on Experimentally Induced Common Cold.
Status: COMPLETED
Conditions: Common Cold
Interventions: DEVICE: ColdZyme® mouth spray|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Chemotherapy With or Without Hepatic Arterial Infusion for Patients With Unresectable Metastatic Colorectal Cancer to the Liver
Status: WITHDRAWN
Conditions: Colorectal Adenocarcinoma Metastatic to the Liver
Interventions: DRUG: Floxuridine (FUDR)|DRUG: Irinotecan (CPT-11)|DRUG: FLUOROURACIL|DRUG: PANITUMUMAB|DRUG: DEXAMETHASONE|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics
Status: COMPLETED
Conditions: Bacteremia
Interventions: DRUG: DSTA4637S|DRUG: Placebo|DRUG: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention
Status: RECRUITING
Conditions: First Episode Psychosis|Psychosis|Psychotic Episode|Psychoses, Affective|Bipolar Disorder|Depressive Psychosis|Schizoaffective Disorder|Schizophreniform Disorders|Schizophrenia|Schizophrenia Spectrum and Other Psychotic Disorders|Substance Induced Psychoses
Interventions: BEHAVIORAL: Active SMS Intervention|BEHAVIORAL: Sham SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Lipoic Acid on Oxidative, Inflammatory and Functional Markers in Asthmatic Patients
Status: COMPLETED
Conditions: Asthma|Allergic Rhinitis
Interventions: DIETARY_SUPPLEMENT: Lipoic acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Prolonged-release melatonin|DRUG: Temazepam|DRUG: Zolpidem|DRUG: Placebo to match melatonin, zolpidem and temazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: DRUG: Magnesium Sulphate|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letrozole in Induction of Abortion of Anembryonic Pregnancy
Status: COMPLETED
Conditions: Anembryonic Pregnancy
Interventions: DRUG: Letrozole tablets|DRUG: Misoprostol Tabets|DRUG: Placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effectiveness Of Ischemic Compression And IASTM In Trigger Point Treatment In Patients With Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tears|Shoulder Pain|Myofascial Trigger Point Pain
Interventions: OTHER: ischemic compression|OTHER: IASTM|OTHER: Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Glycemic Index of Instant Noodle With and Without Soup: Does Serving Method Have an Effect?
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: Instant noodle without soup|OTHER: Instant noodle with soup|OTHER: Glucose reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Microcirculation, Dialysis Modality and Sequestered Salt
Status: NOT_YET_RECRUITING
Conditions: End-stage Renal Disease
Interventions: DEVICE: Hemodialysis (DNa = PNa)|DEVICE: Hemodialysis (DNa<PNa)|DEVICE: Hemodialysis after isolated ultrafiltration (DNa=PNa)|DEVICE: High volume hemodiafiltration (DNa=PNa)|DEVICE: High volume hemodiafiltration (DNa<PNa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Preoperative Oral Carbohydrates Loading in Patients at High Risk of Postoperative Nausea and Vomiting Undergoing Spinal Surgery
Status: UNKNOWN
Conditions: Spinal Disease
Interventions: OTHER: oral carbohydrate beverage|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine as Prophylaxis for COVID-19 in Healthcare Workers (HCQPreP)
Status: UNKNOWN
Conditions: COVID-19|Corona Virus Infection|Wuhan Coronavirus|Prophylaxis|Healthcare Worker|Sars-CoV2|Hydroxychloroquine
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: M-Suubi: A Multi-Level Integrated Intervention to Reduce the Impact of HIV Stigma
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE|BEHAVIORAL: Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE plus Group-based stigma reduction for educators (GED-HIVSR).|OTHER: Bolstered Standard of Care (BSOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PTSD Symptom Reduction by Propranolol Given After Trauma Memory Activation
Status: TERMINATED
Conditions: Posttraumatic Stress Disorders
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 14-day Double Therapy Versus Bismuth Quadruple Therapy in First-line Treatment of Helicobacter Pylori Infection
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 14-day high-dose Tegoprazan Dual Therapy (HDDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Stent Patency in Patients With Benign Biliary Obstruction of the Wing Biliary Stent (Viaduct™)
Status: UNKNOWN
Conditions: Bile Duct Stricture
Interventions: OTHER: Liver Function Tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Liraglutide, a GLP-1 Receptor Agonist, on Brown Adipose Tissue (BAT) Activity in Humans
Status: UNKNOWN
Conditions: Obesity|Type 2 Diabetes Mellitus
Interventions: DRUG: Liraglutide 3.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Supportive Nursing Interventions of Mothers of Infants in Neonatal Intensive Care Unit
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Supportive interventions on the stress levels of mothers of infants hospitalized in the Neonatal Intensive Care Unit (NICU).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Acupuncture as a Treatment for Faecal Incontinence
Status: UNKNOWN
Conditions: Faecal Incontinence
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Best Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Propranolol on the Autonomic Nervous System and Muscle Pain
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders|Myofascial Temporomandibular Disorders
Interventions: DRUG: Propranololhydrochlorid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: 4-Day Primary Irritation Patch Test of MIS Solution
Status: COMPLETED
Conditions: Healthy|Irritation/Irritant|Reactions Adverse
Interventions: DEVICE: NS Solution|OTHER: Normal Saline|OTHER: SLS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neuromodulation Techniques After SCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injury
Interventions: DEVICE: EAW+SCES (exoskelton and spinal cord epidural stimulation)|DEVICE: EAW+TS (exoskelton and transspinal stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dose-response of Physical Exercise on Pelvic Floor Muscle Function in Postmenopausal Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Pelvic Floor Muscle Weakness
Interventions: OTHER: general exercise|OTHER: pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine After Thyroidectomy
Status: COMPLETED
Conditions: Thyroid Tumor
Interventions: DRUG: Desflurane|DRUG: Remifentanil|PROCEDURE: Thyroidectomy|OTHER: Vital signs|BEHAVIORAL: Cough reflex|BEHAVIORAL: Ramsay Sedation Scale|OTHER: Extubation time and Recovery time|BEHAVIORAL: Visual analogue scale|OTHER: Postoperative bleeding|OTHER: Postoperative complications|OTHER: Time to remove drainage and duration of hospital staying|DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide fixed-dose combination (FDC)|DRUG: Emtricitabine/tenofovir alafenamide FDC|DRUG: Darunavir|DRUG: Cobicistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SciBase International Melanoma Pivotal Study
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DEVICE: SciBase III Electrical Impedance Spectrometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of RP-6306 With FOLFIRI in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: RP-6306 (oral PKMYT1 inhibitor)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-effectiveness of the T-Control® Catheter in Patients With Acute Urine Retention
Status: WITHDRAWN
Conditions: Urinary Retention|Catheter-Associated Urinary Tract Infection|Catheter Complications
Interventions: DEVICE: Foley catheter|DEVICE: T-Control catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Type 2 Diabetes and Dietary Regulation on VLDL1-and VLDL2-triglyceride Metabolism
Status: COMPLETED
Conditions: Type 2 Diabetes|Dyslipidemia
Interventions: DRUG: Insulin|DRUG: insulin|OTHER: diet|OTHER: no diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Active Comparator Study of Generex Oral-lyn™ Spray and Injected Human Insulin
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DRUG: Generex Oral-lyn™|DRUG: Regular human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Cholecystectomy vs Hybrid Natural Orifice Translumenal Surgery
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: PROCEDURE: Transvaginal hybrid NOTES cholecystectomy|PROCEDURE: Cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Phase II Study of IMC-A12 in Patients With Thymoma and Thymic Carcinoma Who Have Been Previously Treated With Chemotherapy
Status: COMPLETED
Conditions: Thymoma|Thymic Carcinoma|Thymic Carcinoid|Thymic Neuroendocrine Tumors
Interventions: DRUG: IMC-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Breast Cancer That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: erlotinib hydrochloride|GENETIC: TUNEL assay|GENETIC: protein expression analysis|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: matrix-assisted laser desorption ionization mass spectrometry|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Training in the 21st Century: Using Virtual Role-Plays to Improve Nurse Communication for Medication Adherence
Status: COMPLETED
Conditions: High Blood Pressure|Hypertension
Interventions: BEHAVIORAL: Audiotaped Counseling Session
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Effects of Mango Leaf Extract on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study
Status: COMPLETED
Conditions: Attention|Cognition|Mood
Interventions: OTHER: Mango leaf extract capsule|OTHER: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of Repeated Dosing of a Cytotoxic Lymphocytes (CTL) Based Prostate Cancer Therapy
Status: COMPLETED
Conditions: Hormone-refractory Prostate Cancer
Interventions: BIOLOGICAL: ALECSAT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relation Between MicroRNA 203 and 210 and Sparing the Laparoscopic Examination in Cases of Unexplained Infertility
Status: COMPLETED
Conditions: Infertility Unexplained|Endometriosis
Interventions: PROCEDURE: Laparoscopic Exploration|DIAGNOSTIC_TEST: Estimation of Plasma Expression level of MICRO RNA 203 & 210
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Single Ascending Doses of Elsulfavirine to Evaluate the Safety, Tolerability, and Pharmacokinetics of Elsulfavirine and Its Active Metabolite VM-1500A in Healthy Subjects
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Elsulfavirine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GPED for Patients With Relapsed/Refractory or Advanced NK/T-cell Lymphoma
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: DRUG: Gemcitabine|DRUG: Pegaspargase|DRUG: Etoposide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Heparin Treatment to Reduce Transmission Among Household Contacts of COVID 19 Positive Adults and Children
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: unfractionated heparin|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer Disease
Interventions: DIETARY_SUPPLEMENT: Yeast beta-glucan|DIETARY_SUPPLEMENT: Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Culturally-Adapting a Communication Intervention to Improve Palliative Care Literacy on Two Native American Reservations
Status: WITHDRAWN
Conditions: Advance Care Planning
Interventions: OTHER: Cultural adaptation/implementation COMFORT CC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of BL-M11D1 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)
Interventions: DRUG: BL-M11D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Isradipine for Cognitive Enhancement in Schizophrenia and Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: isradipine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Viral Suppression After Analytic Treatment Interruption in Thai Patients Who Initiated Highly Active Antiretroviral Therapy During Acute HIV Infection
Status: COMPLETED
Conditions: Acute HIV Infection|Antiretroviral Treatment Interruption
Interventions: OTHER: Treatment interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients
Status: COMPLETED
Conditions: Covid 19 Infection
Interventions: OTHER: Respiratory Training|OTHER: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal and Health-related Quality of Life Outcomes in Patients With Simultaneous Pancreas-Kidney Transplants
Status: COMPLETED
Conditions: Pancreas Transplantation|Kidney Transplantation
Interventions: DRUG: Enteric-coated mycophenolate sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Cisplatin and Radiation in Combination With Sorafenib in Cervical Cancer
Status: COMPLETED
Conditions: Cancer of the Cervix
Interventions: DRUG: Sorafenib|DRUG: Cisplatin|PROCEDURE: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Microneedle Pretreatment on Topical Anesthesia
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Microneedle Roller|DEVICE: Sham microneedle Roller
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase 1 Trial To Evaluate mFOLFOX6 With Selinexor In Patients With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Neoplasm
Interventions: DRUG: Selinexor|DRUG: Oxaliplatin|DRUG: 5-FU|DRUG: Folinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of CR8020, a Monoclonal Antibody Against Influenza A Viruses
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: 2 mg/kg CR8020|BIOLOGICAL: 5 mg/kg CR8020|BIOLOGICAL: 15 mg/kg CR8020|BIOLOGICAL: 30 mg/kg CR8020|BIOLOGICAL: 50 mg/kg CR8020|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Cisplatin in Patients With Solid Tumors
Status: COMPLETED
Conditions: Neoplasms, Malignant
Interventions: DRUG: ombrabulin (AVE8062)|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Efficacy and Safety of Passive Immunization With TNM002 Injection and Human Tetanus Immunoglobulin as Prophylaxis Against Tetanus
Status: COMPLETED
Conditions: Tetanus
Interventions: DRUG: TNM002|DRUG: Human tetanus immunoglobulin (HTIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Shock Wave Versus Iontophoresis in Treatment of Subjects With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: radial extracorporeal shock wave|DEVICE: iontophoresis|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bacteriophage Therapy in Patients With Prosthetic Joint Infections
Status: WITHDRAWN
Conditions: Prosthetic Joint Infection
Interventions: BIOLOGICAL: Phage Therapy|PROCEDURE: Two-Stage Exchange Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clearance of Asymptomatic Pharyngeal Carriage of Neisseria Gonorrhoeae With or Without Ceftriaxone Treatment: Randomized Non-inferiority Study
Status: NOT_YET_RECRUITING
Conditions: Neisseria Gonorrhoeae Infection|Asymptomatic Pharyngeal Carriage
Interventions: OTHER: Absence of antibiotic treatment|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I EGFR BATs in Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: EGFR BATs with TMZ following SOC RT/TMZ|DRUG: Weekly EGFR BATs following SOC RT/TMZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of hzVSFv13 in Patients With COVID-19 Pneumonia
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: hzVSF-v13|DRUG: Placebo (Normal saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MEK162 With Gemcitabine and Oxaliplatin in Biliary Cancer
Status: WITHDRAWN
Conditions: Biliary Tract Carcinoma|Gallbladder Carcinoma
Interventions: DRUG: MEK 162|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: LMY-920
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-utility Analysis of the Outpatient Versus Conventional Hospitalization in Treatment of Occlusive Arterial Disease
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Treatment of Occlusive Arterial Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing SLNE With or Without Preoperative Hybrid SPECT/CT in Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Melanoma
Interventions: PROCEDURE: SLNE with preoperative hybrid SPECT/CT|PROCEDURE: Standard SLNE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreas Allotransplantation for Diabetic Nephropathy and Mild Chronic REnal fAilure Stage Study
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Isolated Pancreas Transplant|DRUG: Intensive Insulin Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AMG 853 Phase 2 Study in Subjects With Inadequately Controlled Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AMG 853|DRUG: AMG 853|DRUG: AMG 853|DRUG: AMG 853|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Omission of SLNB in cN0 Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Clinically Assessed Negative Axillary Lymph Nodes|Sentinel Lymph Node
Interventions: PROCEDURE: Omit SLNB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Safety of the Transplantation (by Injection) of Human Glial Restricted Progenitor Cells (hGRPs; Q-Cells®) Into Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Q-Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative ERAS Based Nursing Intervention for Laryngeal Cancer Patients
Status: UNKNOWN
Conditions: Laryngeal Cancer|Nursing
Interventions: OTHER: Routine nursing care|OTHER: Perioperative Enhanced Recovery After Surgery (ERAS) Based Nursing Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Antisense Oligonucleotides in Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: AVI-4658 (PMO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alternating and Direct Current Stimulation for Neuropathic Eye Pain
Status: RECRUITING
Conditions: Eye Pain|Neuropathy, Optic|Cerebral Injury
Interventions: DEVICE: DC-Stimulator Plus (NeuroConn GmbH, Germany)|DEVICE: Sooma direct current stimulator (Sooma, Finland)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dynamics of Insulin Absorption in Subclinical Lipohypertrophy Using the Euglycemic Clamp Technique
Status: SUSPENDED
Conditions: Diabetes Mellitus|Lipohypertrophy
Interventions: DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: mRNA-2736 for Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Status: WITHDRAWN
Conditions: Relapsed or Refractory Multiple Myeloma
Interventions: BIOLOGICAL: mRNA-2736
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivastigmine BA Trial With Multiple Application of Transdermal Patches, Adaptation and Tapering Phase
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: RIV-TDS 13.3 mg/24 h|DRUG: Exelon® 13.3 mg/24 hours transdermal patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Ranibizumab in Diabetic Macular Edema With Center Involvement
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab 0.3 mg|DRUG: Ranibizumab 0.5 mg|DRUG: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temporary Simultaneous Two-arterial Occlusions During Laparoscopic Myomectomy
Status: COMPLETED
Conditions: Myoma
Interventions: PROCEDURE: LM with TESTO|PROCEDURE: LM without TESTO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Excretion and Metabolism of 14C-ETX2514 Administered Intravenously in Healthy Male Subjects
Status: COMPLETED
Conditions: Acinetobacter Baumannii-calcoaceticus Complex Infections
Interventions: DRUG: ETX2514|DRUG: 14C-ETX2514
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group-based Mindfulness for Chronic Pain in the Primary Care Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain|Back Pain
Interventions: OTHER: Group medical visits with mindfulness-based stress reduction|OTHER: Usual PCP care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma, IDH-Wildtype|MGMT-Unmethylated Glioblastoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Magnetic Resonance Imaging|RADIATION: Radiation Therapy|DRUG: STAT3 Inhibitor WP1066|PROCEDURE: Surgical Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Instylla HES Hypervascular Tumor Pivotal Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypervascular Tumors
Interventions: DEVICE: Instylla HES|OTHER: TAE or cTACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retreatment Study of Galiximab + Rituximab in Follicular Non-Hodgkin's Lymphoma (NHL)
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin's
Interventions: DRUG: galiximab in combination with rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lifestyle Factors and Hormone Function on Breast Density in Healthy Hispanic Women Who Are Undergoing Mammography for Breast Cancer Screening
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: physiologic testing|OTHER: study of socioeconomic and demographic variables|PROCEDURE: breast imaging study|PROCEDURE: study of high risk factors
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SCREENING
Clinical trial: Restoring Normal Sagittal Thoracic Posture Improves Management Outcomes in Patients With Chronic Nonspecific Neck Pain
Status: UNKNOWN
Conditions: Rehabilitation
Interventions: OTHER: Denneroll traction|OTHER: Multimodal Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Versus Standard of Care for Patients With Excessive Atrial Ectopy or Short Atrial Runs and High Embolism Risk
Status: NOT_YET_RECRUITING
Conditions: Excessive Supraventricular Ectopies or Short Atrial Runs (ESVEA)
Interventions: DRUG: Rivaroxaban group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rimegepant in Moderate Plaque-type Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cabazitaxel With Radiation and Hormone Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Cabazitaxel|RADIATION: Intensity Modulated Radiation Therapy (IMRT)|DRUG: Anti-Androgen Therapy: Bicalutamide|GENETIC: Luteinizing Hormone-Releasing Hormone (LHRH) Agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial To Evaluate A Multivalent Pneumococcal Conjugate Vaccine In Healthy Adults 50-85 Years Of Age
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: Multivalent|BIOLOGICAL: Tdap|BIOLOGICAL: polysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Falciformopexy for Treatment Perforated Peptic Ulcer.
Status: NOT_YET_RECRUITING
Conditions: Perforated Peptic Ulcer
Interventions: PROCEDURE: Falciformopexy for Treatment Perforated Peptic Ulcer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shivering Prevention During Cesarean Section by Intrathecal Injection of Magnesium Sulfate
Status: COMPLETED
Conditions: Cesarean Section; Shivering
Interventions: DRUG: MgSo4|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION