pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Neurofilament Light Protein in Peripheral Blood Used as a Biomarker for Neurotoxicity After Isolated Limb Perfusion.
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: PROCEDURE: Neurofilament light protein measurement in Isolated limb perfused patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
Status: COMPLETED
Conditions: Chronic Renal Failure|Chronic Kidney Disease|Anemia
Interventions: DRUG: peginesatide|DRUG: Epoetin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anabolic Steroid and Propranolol in Paediatric Burn
Status: RECRUITING
Conditions: Arrest|Bone|Development|Growth
Interventions: DRUG: Propranolol|DRUG: Nandrolone Decanoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Choosing Healthy Activities and Lifestyle Management Through Portal Support
Status: RECRUITING
Conditions: Weight Loss|Overweight and Obesity|Behavior, Health
Interventions: BEHAVIORAL: Active Intervention Group|BEHAVIORAL: Comparison Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality Glasses on Pain Level and Hemo-Dynamic Variables After Open Heart Surgery
Status: NOT_YET_RECRUITING
Conditions: Pain|Hemodynamic Instability
Interventions: OTHER: virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Stellate Ganglion Block on Postoperative Sleep Disturbance and Cognitive Function in Elderly Surgical Patients
Status: COMPLETED
Conditions: Stellate Ganglion Block
Interventions: PROCEDURE: Stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Over and Under/Aneugraft Pericardium Covered Stent Long Term Follow up Registry
Status: UNKNOWN
Conditions: Diseased Saphenous Vein Grafts|Aneurysmal Coronary Arteries
Interventions: DEVICE: Pericardium Covered Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outpatient Registry Trial of Respiratory Tract Infections in Adults
Status: WITHDRAWN
Conditions: Pneumonia, Bacterial|Bronchitis, Chronic
Interventions: DRUG: azithromycin|DRUG: telithromycin|DRUG: Clarythromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Efficacy Trial of Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Autistic Disorder|Autism Spectrum Disorder|Asperger Syndrome|Pervasive Developmental Disorder
Interventions: BEHAVIORAL: Cognitive Enhancement Therapy|BEHAVIORAL: Enriched Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Short-Term Effect of Dietary Carbohydrate Restriction Versus Exogenous Ketone Supplementation on Myocardial Glucose Suppression and Timing to Achieve a State of Ketosis Using FDG PET/CT Serial Imaging
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: FDG|DIETARY_SUPPLEMENT: Ketone Drink|OTHER: Ketogenetic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: the Efficacy and Safety of Anlotinib Combined With Almonertinib in the First-line Treatment of Patients With Brain Metastases From EGFR Mutation-positive Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer|Brain Metastases
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Sensor Controlled Compliance Analysis of Shoulder Abduction Splint After Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: BEHAVIORAL: Abduction brace wearing time analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability Study of Cinnamon in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Males
Interventions: OTHER: cinnamon|OTHER: Oatmeal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Insulin Detemir in Type 2 Diabetes Inadequately Controlled on OHA Therapy Alone
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin NPH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment
Status: UNKNOWN
Conditions: Aortic Coarctation|Arterial Stiffness|PULSE WAVE VELOCITY|Functional Magnetic Resonance Imaging|Vascular Endothelium
Interventions: PROCEDURE: Surgery|PROCEDURE: Balloon dilation|PROCEDURE: Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Directional Versus Orbital Atherectomy Plaque Modification and Luminal Area Assessment of the Femoro-popliteal Artery Via Intravascular Ultrasound
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: DEVICE: Percutaneous Revascularization of the Femoropopliteal Arteries using a DAS|DEVICE: Percutaneous Revascularization of the Femoropopliteal Arteries using a OAS device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the TEGO Connector in Preventing Tunneled Cuffed Hemodialysis Catheters From Dysfunction and/or Bacteremia
Status: COMPLETED
Conditions: Other Complication of Vascular Dialysis Catheter
Interventions: DEVICE: TEGO connector®|DRUG: Trisodium citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Facilitating Employment for Youth With Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autism|Asperger Syndrome|Pervasive Developmental Disorder|Adolescent Development
Interventions: BEHAVIORAL: Project SEARCH Plus ASD Supports
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Safety and Effectiveness of Remimazolam Tosilate for Injection for Short-term Elective Surgery in Adults
Status: COMPLETED
Conditions: Hypotension During Surgery
Interventions: DRUG: Remimazolam Tosilate for Injection 0.1mg/kg|DRUG: Remimazolam Tosilate for Injection 0.15mg/kg|DRUG: Remimazolam Tosilate for Injection 0.2mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Local Anesthesia on Post-operative Pain During Laparoscopic Inguinal Hernia Repair
Status: COMPLETED
Conditions: Post Operative Pain (Post Laparoscopic Hernia Repair)
Interventions: DRUG: 0.5% Bupivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimizing Tourniquet Pressures in Paediatric Orthopaedic Knee Surgery
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Repair
Interventions: DEVICE: Tourniquet instrument capable of measuring LOP in combination with tourniquet cuffs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Anabolic Effect of Perioperative Nutrition With Insulin While Maintaining Normoglycemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Travasol (amino acid injection)|DRUG: Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence|Smoking, Cigarette|Smoking Cessation|Smoking Behaviors|Smoking Reduction|Craving
Interventions: DRUG: Isradipine|BEHAVIORAL: Cue Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Hip and Knee Focused Exercises Versus Hip and Knee Focused Exercises With the Use of Blood Flow Restriction Training in Adults With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Exercise with Blood Flow restriction training|OTHER: Hip and Knee Exercise Program|OTHER: stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CARNIVAL Type I: Valproic Acid and Carnitine in Infants With Spinal Muscular Atrophy (SMA) Type I
Status: COMPLETED
Conditions: Spinal Muscular Atrophy Type I
Interventions: DRUG: Valproic Acid and Levocarnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Major Cardiovascular Events in Patients With Nonvalvular Atrial Fibrillation Treated With Rivaroxaban
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease
Status: ENROLLING_BY_INVITATION
Conditions: ST Elevation Myocardial Infarction|Multi-Vessel Coronary Artery Stenosis
Interventions: PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Randomized, Placebo-controlled, Single & Multiple Dose Escalation Study to Investigate Safety, Pharmacokinetics, and Pharmacodynamics of SHR0534 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SHR0534|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics
Status: TERMINATED
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Loop diuretics (furosemide, torsemide, bumetanide)|OTHER: Ultrafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen
Status: TERMINATED
Conditions: Oral Lichen Planus
Interventions: DRUG: TOPICAL SIROLIMUS (RAPAMUNE*)|DRUG: TOPICAL BETAMETHASONE 0.05%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability of Rebif® Injection With and Without the Use of Rebiject™Mini in Relapsing-Remitting Multiple Sclerosis Subjects
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-remitting
Interventions: DEVICE: Rebif® via Rebiject™Mini|DEVICE: Rebif® via manual injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults
Status: COMPLETED
Conditions: Pain, Postoperative|Medication Adherence|Opioid Use|Knowledge, Attitudes, Practice|Risk Reduction Behavior
Interventions: BEHAVIORAL: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fat Grafting Technique Using Autologous Adipose Tissue Lipogems in Patients Suffering From Stress Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence,Stress
Interventions: PROCEDURE: Autologous adipose tissue harvesting/grafting using Lipogems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients With Endometriosis.
Status: RECRUITING
Conditions: Endometriosis|Dyspareunia|Pelvic Pain
Interventions: DEVICE: Transvaginal photobiomodulation|DEVICE: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharynx Cancer
Interventions: DRUG: Carboplatin|RADIATION: Radiation Therapy|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monthly Itraconazole Versus Classic Homeopathy for Treatment of Recurrent Vulvovaginal Candidiasis (RVVC)
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: DRUG: itraconazole|DRUG: lactobacillus gasseri|DRUG: classic homeopathy (carcinosin M, nux vomica, pulsatilla M, ferrum metallicum, sepia M, etc. as prescribed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Oral Vinorelbine Combination With Tislelizumab in EGFR/ALK-negative Advanced NSCLC
Status: ENROLLING_BY_INVITATION
Conditions: EGFR/ ALK-negative Advanced NSCLC
Interventions: DRUG: tislelizumab and metronomic oral vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
Status: COMPLETED
Conditions: Birth Outcome, Adverse|Labor Long|Labor Complication|Maternal Injury|Maternal Distress During Labor and Delivery|Neonatal and Perinatal Conditions|Labor Duration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using Mukbang to Improve Appetite, Nutritional Status and Quality of Life in Children With Cancer
Status: NOT_YET_RECRUITING
Conditions: Children With Cancer
Interventions: BEHAVIORAL: Active Ingredient Mukbang|BEHAVIORAL: Common Mukbang|BEHAVIORAL: General short videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Psychological Experience of Pathological Pregnancy. Study of the Case of Premature Rupture of Membranes and Evaluation of the Impact of Hypnosis Support
Status: UNKNOWN
Conditions: Preterm Premature Rupture of Membrane
Interventions: OTHER: hypnosis|OTHER: standart care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: DRUG: Placebo|DRUG: Semaglutide (Rybelsus®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study to Evaluate the Predictive Value of the Heart Failure Questionnaire (HF-Q) for the Occurrence of Μajor Αdverse Cardiovascular Events (MACE) in Patients With Symptomatic Heart Failure
Status: WITHDRAWN
Conditions: Heart Failure|Heart Failure NYHA Class III|Heart Failure NYHA Class II|Heart Failure NYHA Class IV
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Ezetimibe with simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Immunotherapy Plus Chemotherapy for Potentially Resectable Stage IIIA/IIIB Non-Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: IIIA Stage Non-small Cell Lung Cancer
Interventions: DRUG: Sintilimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Multimodal Physical Therapy With and Without McConnell Taping in Patients With Anterior Knee Pain.
Status: RECRUITING
Conditions: Anterior Knee Pain Syndrome
Interventions: OTHER: Multimodal therapy with McConnell taping|OTHER: Multimodal therapy without McConnell taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immunomodulatory Effects of Silymarin in Patients With Beta-Thalassemia Major
Status: COMPLETED
Conditions: Immune Abnormalities
Interventions: DRUG: Desferrioxamine, Legalon® (Silymarin)|DRUG: Silymarin (Legalon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Clinical Trial of Vidaza With Abraxane in Patients With Advanced/Metastatic Solid Tumors and Breast Cancer
Status: COMPLETED
Conditions: Advanced or Metastatic Solid Tumors|Advanced or Metastatic Breast Cancer
Interventions: DRUG: Azacitidine (Vidaza)|DRUG: Nab-paclitaxel (Abraxane)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of SOL-804 in Healthy Male Subjects
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: SOL-804-F|DRUG: Zytiga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment
Status: COMPLETED
Conditions: Antibiotic Therapy
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Mircera for the Maintenance Treatment of Anemia in Dialysis Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Darbepoetin alfa|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment
Status: RECRUITING
Conditions: Ductal Carcinoma in Situ
Interventions: DRUG: Tamoxifen|DRUG: Exemestane|DRUG: Letrozole|DRUG: Anastrazole|DRUG: Testosterone + Anastrazole|DRUG: Elacestrant|DRUG: Z-endoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Effect of Magnesium Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia on Postoperative Pain Control in Pediatric Patients Undergoing Inguinal Hernia Repair
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: caudal block|DRUG: normal saline 0.5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Floxuridine, Dexamethasone, and Irinotecan After Surgery in Treating Patients With Liver Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: dexamethasone|DRUG: floxuridine|DRUG: irinotecan hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT
Status: TERMINATED
Conditions: Lymphoma, B-cell|Lymphoma, Non-Hodgkin|Diffuse Large B-cell Lymphoma (DLBCL)|Malignant Lymphoma, Non-Hodgkin
Interventions: PROCEDURE: Autologous hematopoietic stem cell transplantation (auto-HSCT)|PROCEDURE: Allogeneic hematopoietic stem cell transplantation (allo-HSCT)|PROCEDURE: Total lymphoid irradiation (TLI)|DRUG: Rituximab|DRUG: Carmustine|DRUG: Etoposide|DRUG: Filgrastim|DRUG: Anti-thymocyte globulin (ATG)|DRUG: Cyclosporine|DRUG: Mycophenolate mofetil (MMF)|DRUG: Cyclophosphamide|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Hydrocortisone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Local Doxycycline on the Outcomes of Periodontal Regeneration
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Decontamination of the pocket with local doxycycline|PROCEDURE: Decontamination of the pocket with mechanical instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Multimodal Opioid Therapy During Hepatic Resection Surgery
Status: UNKNOWN
Conditions: Liver Dysfunction|Pain
Interventions: DRUG: Morphine sulphate|DRUG: Morphine hydrochloride, remifentanil hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial To Study The Effect Of Lamivudine In Adult Patients Who Suffer From Chronic Hepatitis B Alone
Status: COMPLETED
Conditions: CHRONIC HEPATITIS B
Interventions: DRUG: LAMIVUDINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single- Versus Double-balloon Enteroscopy in Small Bowel Diagnostics
Status: COMPLETED
Conditions: Gastrointestinal Diseases
Interventions: DEVICE: Double-balloon procedure (DBE)|DEVICE: Single-balloon procedure (SBE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot
Status: RECRUITING
Conditions: Tetralogy of Fallot|Ventricular Tachycardia|Sudden Cardiac Death
Interventions: DIAGNOSTIC_TEST: Electroanatomic substrate mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Chinese Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Domperidone|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dairy- and Berry-based Snacks on Postprandial Glucose Metabolism in Older People
Status: COMPLETED
Conditions: Postprandial Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Dairy snack|DIETARY_SUPPLEMENT: Berry snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Long-term Effects Secondary to Cancer Therapy in Children|Perioperative/Postoperative Complications|Psychosocial Effects of Cancer and Its Treatment|Weight Changes
Interventions: OTHER: metabolic assessment|OTHER: physiologic testing|PROCEDURE: biopsy|PROCEDURE: computed tomography|PROCEDURE: conventional surgery|PROCEDURE: magnetic resonance imaging|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Efficacy and Safety of GX-E2 in the Anemic Patients Diagnosed With Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: GX-E2|DRUG: GX-E2|DRUG: GX-E2|DRUG: NESP|DRUG: MIRCERA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Examining Arts as Therapy in Children With Cancer, CREATe Trial
Status: RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Interventions: PROCEDURE: Art Therapy|PROCEDURE: Discussion|OTHER: Media Intervention|OTHER: Survey Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency of Spatially Distributed Sequential Stimulation (Sdss) for Functional Electrical Stimulation (FES) of Upper Motor Neuron Syndrome (UMR) Patients
Status: RECRUITING
Conditions: Upper Motor Neuron Disease
Interventions: DEVICE: SDSS|DEVICE: Standard Electrical Stimulation During Functional Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm
Status: RECRUITING
Conditions: Lung Adenocarcinoma
Interventions: PROCEDURE: Lobectomy with systemic lymph node dissection|PROCEDURE: Segmentectomy with systemic lymph node dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Antiinflammatory Diet as Modulator of Cardiometabolic Risk and Body Weight in Healthy Subjects
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Resistance|Overweight
Interventions: OTHER: Multifunctional diet (MFD)|OTHER: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant
Status: TERMINATED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Myeloid Leukemia in Remission
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Massage for GAD: Neuroimaging and Clinical Correlates of Response
Status: ACTIVE_NOT_RECRUITING
Conditions: Generalized Anxiety Disorder
Interventions: OTHER: Swedish Massage Therapy|OTHER: Light Touch Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder
Status: COMPLETED
Conditions: Carcinoma, Transitional Cell|Bladder Cancer|Bladder Neoplasm
Interventions: DRUG: Pralatrexate Injection|DIETARY_SUPPLEMENT: Vitamin B12|DIETARY_SUPPLEMENT: Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of SAR231893 (REGN668) in Healthy Japanese Adult Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SAR231893 (REGN668)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant Recipient
Status: UNKNOWN
Conditions: Acute Rejection of Renal Transplant
Interventions: DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Impact of Pharmacist-led Cognitive Behavioral Intervention on Adherence and Quality of Life of Epileptic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: BEHAVIORAL: Pharmacist-led Cognitive Behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Metabolic Effects of Plant-based Diet
Status: COMPLETED
Conditions: Healthy Diet|Fatty Liver|Insulin Resistance|Metabolic Syndrome|Healthy Lifestyle|Healthy Nutrition
Interventions: DIETARY_SUPPLEMENT: Omnivore|DIETARY_SUPPLEMENT: Vegetarian|DIETARY_SUPPLEMENT: Vegan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PF-06842874 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: PF-06842874|DRUG: Placebo|DRUG: Relative Bioavailability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rovalpituzumab Tesirine (SC16LD6.5) in Recurrent Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Small Cell Lung Cancer
Interventions: DRUG: Rovalpituzumab tesirine (SC16LD6.5)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Ultra" Enhanced Recovery After Surgery (E.R.A.S.) in Laparoscopic Colectomy for Cancer
Status: COMPLETED
Conditions: Colonic Cancer
Interventions: OTHER: "Ultra" E.R.A.S.|OTHER: Classic E.R.A.S.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification and Treatment Of Micrometastatic Disease in Stage III Colon Cancer
Status: RECRUITING
Conditions: Metastatic Colon Cancer|Stage III Colon Cancer
Interventions: DRUG: FOLFIRI Protocol|OTHER: ACTIVE SURVEILLANCE|DRUG: Nivolumab Protocol|DRUG: Encorafenib/Binimetinib/Cetuximab Protocol|DRUG: Trastuzumab + Pertuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Melanoma|Nasopharyngeal Carcinoma|Microsatellite Stable Colorectal Cancer|Triple Negative Breast Cancer
Interventions: DRUG: DKY709|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determination of Lysine Requirement in the Parenterally Fed Neonate
Status: COMPLETED
Conditions: Parenteral Lysine Requirements|Parenteral Feedings
Interventions: DIETARY_SUPPLEMENT: Amino Acid Solution with different amount of Lysine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Physical training and high protein diet|OTHER: Physical training and low protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects
Status: COMPLETED
Conditions: Periodontitis, Adult
Interventions: BIOLOGICAL: advanced PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Clinical Trial of PRS TB Regimen I - Phase II
Status: COMPLETED
Conditions: Pulmonary Tuberculosis TB in Sputum: (+) Microscopy
Interventions: DRUG: Group A (the standard 2HRZE/4HR regimen）|DRUG: Group B (New short course PRS regimen, 4EZ(high dose)PtoCfz)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Recombinant SeV-hFGF2/dF Injection for PAOD
Status: UNKNOWN
Conditions: PAOD - Peripheral Arterial Occlusive Disease|PAD|Critical Limb Ischemia
Interventions: BIOLOGICAL: Recombinant SeV-hFGF2/dF Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MRG002 Versus Investigator's Choice of Chemotherapy in the Treatment of Patients With HER2-positive Unresectable Advanced or Metastatic Urothelial Cancer
Status: RECRUITING
Conditions: Advanced or Metastatic Urothelium Cancer
Interventions: DRUG: MRG002|DRUG: Docetaxel Injection|DRUG: Paclitaxel Injection|DRUG: Gemcitabine Hydrochloride for Injection|DRUG: Pemetrexed Disodium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Status: RECRUITING
Conditions: Primary Progressive Aphasia|Dementia|Dementia, Frontotemporal|Alzheimer Disease|Neurodegenerative Diseases|Frontotemporal Lobar Degeneration|Apraxia, Motor|Dysarthria|Communication Disorders|Language Disorders|Speech Disorders|Neurocognitive Disorders|Aphasia|Bilingual Aphasia
Interventions: BEHAVIORAL: Video-Implemented Script Training for Aphasia (VISTA)|BEHAVIORAL: Lexical Retrieval Training (LRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of NAC for the Prevention and Relief of PIPN in Women With Ovarian, Tubal, and Peritoneal Cancer
Status: COMPLETED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: N Acetylcysteine A|DRUG: N Acetylcysteine B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Examining the Individual Response to a Restricted Sodium Diet in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Modified Sodium Watcher Program + Digital Self-Monitoring|BEHAVIORAL: Usual care + Digital Self-Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Prevention Of Postmenopausal Osteoporosis With Lasofoxifene And Cytokine Evaluation
Status: COMPLETED
Conditions: Bone Loss
Interventions: DRUG: Lasofoxifene|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)
Status: UNKNOWN
Conditions: Lymphoblastic Leukemia, Acute
Interventions: DRUG: Methotrexate|DRUG: Prednisolone|DRUG: Dexamethasone|DRUG: Vincristine|DRUG: Pirarubicin|DRUG: Cyclophosphamide|DRUG: L-asparaginase|DRUG: Cytarabine|DRUG: Hydrocortisone|DRUG: Mercaptopurine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Propionate on Energy Homeostasis
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Placebo (Sodium Chloride)|OTHER: Exercise|DIETARY_SUPPLEMENT: Sodium Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Curcumin in the Lower Gastrointestinal Tract in Familial Adenomatous Polyposis Patients
Status: WITHDRAWN
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Static Stretching and Deep Kneading Massage Among Plantar Fasciitis Patients
Status: UNKNOWN
Conditions: Plantar Fasciitis
Interventions: BEHAVIORAL: Static Stretching|BEHAVIORAL: Deep Kneading Massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Dobutamine on Microcirculation, Regional and Peripheral Perfusion in Septic Shock Patients
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: Dobutamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nemonoxacin 500Mg Capsule|DRUG: Moxifloxacin 400Mg Tablet|DRUG: Nemonoxacin 750Mg Capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sequential Treatment Regimen of Cryotherapy and Picato® for the Treatment of Actinic Keratosis on the Face and Scalp
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: PROCEDURE: Cryotherapy|DRUG: Vehicle|DRUG: Ingenol metabute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Cytoreductive Surgery and HIPEC in Patients With Primary and Secondary Peritoneal Cancers
Status: COMPLETED
Conditions: Stomach Cancer|Colorectal Cancer|Appendiceal Cancer|Ovarian Cancer|Uterine Cancer|Cervical Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DEVICE: HIPEC|DRUG: Mitomycin c|DRUG: CDDP 50|DRUG: CDDP 75|DRUG: Doxorubicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Prophylactic Use of Irrisept Irrigation System for Spinal Instrumentation
Status: NOT_YET_RECRUITING
Conditions: Post-Op Complication|Spine Surgery|Site Infection|Surgical Site Infection|Spinal Instrumentation|Index Spinal Instrumentation|Layer-by-Layer Closure|Locoregional Flap-Based Closure
Interventions: DEVICE: Chlorhexidine gluconate solution|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Polarstem Versus Corail; a Comparison of Micromotion and Periprosthetic Bone Remodelling of Two Femoral Stems
Status: ACTIVE_NOT_RECRUITING
Conditions: Arthritis of the Hip
Interventions: DEVICE: Polarstem|DEVICE: Corail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan
Status: TERMINATED
Conditions: Refractive Error|Myopia|Astigmatism
Interventions: DEVICE: senofilcon A toric soft contact lens|DEVICE: senofilcon A sphere soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Radiation Therapy With or Without Lapatinib in Treating Patients With Locally Advanced Cancer of the Larynx or Hypopharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: docetaxel|DRUG: fluorouracil|DRUG: lapatinib ditosylate|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|GENETIC: in situ hybridization|GENETIC: polymerase chain reaction|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: fludeoxyglucose F 18|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TURBt With Adjuvant Cryoablation to Treat Bladder Cancer
Status: UNKNOWN
Conditions: Urinary Bladder Neoplasms
Interventions: PROCEDURE: Cryoablation|DRUG: Epirubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Myotonometry Quantify Dry Needling Effectiveness on Myofascial Trigger Points?
Status: COMPLETED
Conditions: Muscle Tone Abnormalities
Interventions: DEVICE: MTrP Group|DEVICE: TB Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Methods to Enhance Transcranial Direct Stimulation (tDCS)
Status: COMPLETED
Conditions: Healthy Volunteers|Brain Excitation
Interventions: DEVICE: Transcranial Direct Current Stimulation (tDCS)|DEVICE: Transcranial Direct Current Stimulation (tDCS)|OTHER: Transcranial direct Stimulation (tDCS) and D-cycloserine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
Status: COMPLETED
Conditions: Photoaging|Wrinkle
Interventions: PROCEDURE: Radiofrequency Microneedling|OTHER: Facial Cleanser|OTHER: Facial Moisturizer|OTHER: Sunscreen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Tenofovir DF in HIV-1 Infected Adolescents Failing Their Current Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Tenofovir DF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Trial of the Use of ReCell® Autologous Cell Harvesting Device for Venous Leg Ulcers
Status: COMPLETED
Conditions: Venous Leg Ulcers
Interventions: DEVICE: Standard Care plus ReCell|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Bioavailability of Subcutaneously Administered XmAb®7195
Status: COMPLETED
Conditions: Healthy Volunteers|Atopic Disease
Interventions: DRUG: XmAb7195|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expansion of Invariant NKT Cells for a Cell Immunotherapeutic Approach Allowing the Control of Graft Versus Host-disease and Preserving the Graft Versus Leukemia Effect After Allogeneic Hematopoietic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Allogeneic Hematopoietic Stem Cell (HSC) Transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electromagnetic Stimulation of the Phrenic Nerve in Critically Ill Mechanically Ventilated Patients (STIMIT-II)
Status: TERMINATED
Conditions: Muscle Weakness|Critical Illness|Mechanical Ventilation Complication
Interventions: DEVICE: Non-invasive electromagnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Chiropractic Treatment Using Reaction and Response Times in Members of the Special Operation Forces (ACT2)
Status: COMPLETED
Conditions: Physiological Measurements of Response and Reaction Times
Interventions: OTHER: Chiropractic Manipulative Therapy|OTHER: Wait-list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Support Improves Preoxygenation in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: VS|OTHER: AI-4/PEEP-4|OTHER: AI-6/PEEP-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Exercise With Scleroderma Functional Outcomes
Status: COMPLETED
Conditions: Scleroderma, Systemic|Scleroderma, Diffuse|Scleroderma, Limited|Hand Rheumatism|Mouth Movement Impaired
Interventions: OTHER: Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE