pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Patch Test of Benzalkonium Chloride Disinfectant Spray
Status: COMPLETED
Conditions: Wound Healing
Interventions: DRUG: 0.13% Benzalkonium Chloride|DRUG: SLS Solution|DRUG: Normal Saline Water|OTHER: Empty Finn Chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III, Randomized, Double-Blind, Placebo-Controlled, Trial of Linaclotide Administered to Patients With Chronic Constipation
Status: COMPLETED
Conditions: Chronic Constipation
Interventions: DRUG: Linaclotide 290 micrograms|DRUG: Linaclotide 145 micrograms|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Extended Treatment With Liatermin (r-metHuGDNF) Administered by Continuous Intraputaminal (IPu)Infusion to Subjects With Idiopathic Parkinson's Disease Who Have Completed a Previous Trial of Liatermin
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BIOLOGICAL: Liatermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children
Status: COMPLETED
Conditions: New Daily Persistent Headache (NDPH)
Interventions: DRUG: Naltrexone HCl (Bulk) Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Structured Simplified Short-term Intensive Insulin Therapy on Long-term Glycemic Remission
Status: UNKNOWN
Conditions: Newly Diagnosed Type 2 Diabetes|Simplified Short-term Intensive Insulin Therapy|Glycemic Remission
Interventions: DRUG: Simplified intensive insulin therapy regimen|DRUG: Traditional Short-term Intensive insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure
Interventions: OTHER: Immediate ENABLE nurse coaching, on top of usual care|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patellar Resurfacing in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: PROCEDURE: Patellar component|PROCEDURE: No patellar component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Confirm the Efficacy and Safety of Fixed-dose Combinations of Amlodipine and Candesartan
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: Group I|DRUG: Group II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation as an Analgesic Treatment in Endometriosis Chronic Pain : Feasibility
Status: UNKNOWN
Conditions: Deep Endometriosis|Chronic Pelvic Pain
Interventions: DEVICE: Repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling
Status: RECRUITING
Conditions: Solid Tumor, Unspecified, Child|Relapsed Solid Neoplasm|CNS Tumor
Interventions: DRUG: avapritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Good Idea on Glucose Homeostasis in a Healthy Population
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: GoodIdea|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breathe Easier II: A Dyad-based Multiple Behavior Intervention
Status: COMPLETED
Conditions: Lung Cancer, Nonsmall Cell|COPD|Self-Management|Physical Inactivity|Stress|Quality of Life
Interventions: BEHAVIORAL: Breathe Easier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trans-Middle-Ear Mucosal Gas Exchange Project 1, Specific Aim 1
Status: COMPLETED
Conditions: Middle Ear Gas Exchange
Interventions: DRUG: 6%CO2, 25%O2, balance N2|DRUG: 6% CO2, 0%O2, balance N2|DRUG: 20%CO2, 6%O2, balance N2|DRUG: 0%CO2, 6%O2, balance N2|DRUG: 6% CO2, 6%O2, balance N2|DRUG: 6%CO2, 6%O2, 0%N2, balance argon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Implantation of Add on Lens for Age Related Macular Degeneration Patients With Low Vision
Status: UNKNOWN
Conditions: Inclusion Criteria
Interventions: DEVICE: "Scharioth" macula lens A45sml/A45smy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pencil Beam Proton Therapy for Pelvic Recurrences in Rectal Cancer Patients Previously Treated With Radiotherapy
Status: RECRUITING
Conditions: Rectal Cancer Recurrent
Interventions: RADIATION: Pencil beam proton radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Inflammatory and Metabolic Responses to a High Fat Meal and Plant Polyphenol Blend
Status: COMPLETED
Conditions: Anthocyanins
Interventions: DIETARY_SUPPLEMENT: Plant polyphenol blend|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Diagnostic Value of Portable Ultrasound for Dyspneic Patient Support in the Emergency Department
Status: TERMINATED
Conditions: Dyspnea
Interventions: OTHER: Standard care|DEVICE: Vscan portable ultrasound device (GE Healthcare, Wauwatosa, WI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PEEP Mask for Tracheobronchomalacia-Induced Cough
Status: COMPLETED
Conditions: Tracheobronchomalacia
Interventions: DEVICE: nPEP (non-invasive positive expiratory pressure) mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Ibuprofen 400 and 800 mg Every 6 Hours in the Management of Postoperative Pain.
Status: UNKNOWN
Conditions: Ibuprofen|Nonsteroidal Anti-inflammatory Drug|Intravenous|Injectable|Pain|Analgesic
Interventions: DRUG: ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Conducted in Healthy Subjects to Demonstrate Bioequivalence Between Ropinirole Prolonged Release Tablets Manufactured at Crawley and Aranda
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: Ropinirole XL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electroencephalography Activity in Individuals With Nonspecific Chronic Low Back Pain After Cranial Osteopathic Manipulative Treatment
Status: WITHDRAWN
Conditions: Low Back Pain
Interventions: OTHER: CV4 Cranial (4th ventricle technique) Osteopathic Manipulative|OTHER: CV4 (4th ventricle technique) manual therapy sham technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Relief Using VR in Oocyte Retreival
Status: COMPLETED
Conditions: Infertility|Pain
Interventions: DEVICE: Virtual reality|DEVICE: No virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structured Mobile Technology Based Lifestyle Program vs Usual Care for Patients With Non-alcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease|Non-alcoholic Steatohepatitis
Interventions: OTHER: Usual Care then FitBit|OTHER: FitBit then Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumor
Interventions: DRUG: BL-B01D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Brachytherapy (100/110)|RADIATION: Brachytherapy (125/145)|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Essiac (ESIAK) Versus Placebo to Improve Quality of Life in Transition in Women With Breast or Ovarian Cancer.
Status: TERMINATED
Conditions: Ovarian Cancer|Breast Cancer
Interventions: DRUG: Essiac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Single and Repeated Dose of Roflumilast 500 µg , in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Roflumilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Two Exercise Programs on the Neck.
Status: COMPLETED
Conditions: Subjects With Deep Cervical Muscle Strength Deficit
Interventions: OTHER: Training protocol with the cervical device for treatment (CDAT).|OTHER: Conventional training protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electroencephalographic Signatures of Neuropsychiatric Fluctuations in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: assessment during the transition between OFF-levodopa (i.e. withdrawal of levodopa phase) and ON-levodopa (i.e. effect of Levodopa phase)states
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SBRT Sequential Surufatinib Combined With Immunotherapy for Biliary Tract Carcinoma
Status: RECRUITING
Conditions: Biliary Tract Carcinoma
Interventions: DRUG: SBRT Sequential Surufatinib Combined With Immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrating Pediatric Care Delivery in Rural Healthcare Systems
Status: UNKNOWN
Conditions: Infant Mortality|Under-two Mortality
Interventions: OTHER: Structured Quality Improvement|OTHER: Chronic Care Model|DEVICE: Integrated Electronic Medical Record|DEVICE: Solar-powered electrical supply|BEHAVIORAL: Performance-based financing|OTHER: Existing healthcare system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pathway Study WS3 - Home Based Metacognitive Therapy for Cardiac Rehabilitation Patients
Status: COMPLETED
Conditions: Depression|Anxiety|Cardiac Rehabilitation|Psychological Distress
Interventions: OTHER: Home-based Metacognitive Therapy (Home-MCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Kinetin 0.1% for Treatment of Skin Photoaging
Status: COMPLETED
Conditions: Cutaneous Photoaging
Interventions: OTHER: Kinetin, N6-furfuryladenine, 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Use of Nitazoxanide and Probiotics in Acute Diarrhea Secondary to Rotavirus
Status: COMPLETED
Conditions: Diarrhea|Rotavirus Infection
Interventions: DRUG: Nitazoxanide|DRUG: Probiotic mix preparation|OTHER: Oral hydration solutions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Evaluation of Uptake in Bone Metastases and Biodistribution of [68Ga]P15-041
Status: COMPLETED
Conditions: Prostate Cancer|Bone Metastases
Interventions: DRUG: [68Ga]P15-041
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: " Arthrospira Platensis" as Nutrition Supplementation for Female Adult Patients Infected by HIV in Yaoundé Cameroon
Status: COMPLETED
Conditions: HIV
Interventions: DIETARY_SUPPLEMENT: Arthrospira platensis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: (11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas
Status: TERMINATED
Conditions: Low Grade Glioma|Glioblastoma Multiforme|Anaplastic Astrocytoma|Anaplastic Oligodendroglioma|Oligoastrocytoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Effect of Tocilizumab on Markers of Atherogenic Risk in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction of Cardizem LA (Diltiazem Hydrochloride) on Pitavastatin
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pitavastatin (NK-104)|DRUG: Diltiazem (Cardizem LA) 240 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Pharmacokinetic Study to Evaluate the Effect of a Single Dose of Guselkumab (CNTO 1959) on CYP 450 Enzyme Activities After Subcutaneous Administration in Participants With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Guselkumab|DRUG: Midazolam|DRUG: Warfarin|DRUG: Omeprazole|DRUG: Dextromethorphan|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study to Evaluate the Impact of Duration of Subcutaneous Infusion of a Novel, pH Neutral Formulation of Furosemide (Furoscix®) on Safety and Local Skin Tolerability
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Furosemide 80 mg (8 mg/mL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rule of Carbone Monoxyde in the Ex Vivo Lung Perfusion Reconditionning
Status: UNKNOWN
Conditions: Neurogenic Lung Edema
Interventions: OTHER: Carbone monoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Varenicline Light Smoking Pilot
Status: COMPLETED
Conditions: Smoking Cessation|Smoking Behaviors|Smoking
Interventions: DRUG: Varenicline|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene
Status: NOT_YET_RECRUITING
Conditions: Hyperoxaluria (Disorder)
Interventions: DIAGNOSTIC_TEST: Lithiasis assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Dose Primaquine for Clearance of Gametocytes
Status: COMPLETED
Conditions: Malaria|Asymptomatic Malaria|Plasmodium Falciparum
Interventions: DRUG: Artemether-lumefantrine combination|DRUG: Artemether-Lumefantrine with a single dose of 0.25mg/kg primaquine|DRUG: Artemether-Lumefantrine with a single dose of 0.4mg/kg primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Electrical Stimulation for Management of Orthostatic Instability in Acute Cervical Spinal Cord Injury
Status: COMPLETED
Conditions: Orthostatic Hypotension|Postural Hypotension
Interventions: DEVICE: transcranial electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Recurrent Aphthous Stomatitis With Er,Cr:YSGG Laser Irradiation
Status: COMPLETED
Conditions: Stomatitis, Aphthous
Interventions: DEVICE: Er,Cr:YSGG Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of the Athero-Protective Effects of Clopidogrel
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Electronic Method of Collecting Pain Scores in the Emergency Department
Status: COMPLETED
Conditions: Pain, Acute
Interventions: OTHER: PIMPERNEL Novel Electronic Log: Pain display can be seen|OTHER: PIMPERNEL Novel Electronic Log: Pain display is hidden
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electronic Pre-visit Questionnaire to Prompt Discussions of Youth Violence in Primary Care
Status: COMPLETED
Conditions: Exposure to Violent Event|Bullying
Interventions: BEHAVIORAL: Pre-Visit Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study of Dose-Adjusted EPOCH-Rituximab in Adults With Untreated Burkitt Lymphoma and c-MYC+ Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Burkitt Lymphoma|Diffuse Large B-cell Lymphoma, c-MYC Positive|Plasmablastic Lymphoma
Interventions: DRUG: EPOCH-R|DRUG: EPOCH-RR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of an Electrical Impedance Device Versus Digital Radiography in Estimation of Remaining Dentin Thickness
Status: ACTIVE_NOT_RECRUITING
Conditions: Caries,Dental|Deep Caries
Interventions: DIAGNOSTIC_TEST: electrical impedance device,|DIAGNOSTIC_TEST: Reference test: Digital Radiographic examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Influenza Vaccination of HIV Infected Pregnant Women: Safety and Immunogenicity
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent influenza vaccine|BIOLOGICAL: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assess the Correlation With Severe Respiratory Syncytial Virus Disease in the First 6 Months in Children With Congenital Heart Disease and Maternal Ac-AntiVSR Titers During Pregnancy
Status: UNKNOWN
Conditions: Respiratory Syncytial Virus, Congenital Heart Disease
Interventions: DIAGNOSTIC_TEST: Determination of antibodies in maternal serum IgG for respiratory syncytial virus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Effect of Rifampin on the Metabolism of ABT-199
Status: WITHDRAWN
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: ABT-199|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MK-0524B Lipid Study (MK-0524B-063)
Status: COMPLETED
Conditions: Primary Hypercholesterolemia|Mixed Dyslipidemia
Interventions: DRUG: Comparator: simvastatin|DRUG: MK-0524A|DRUG: Placebo|DRUG: MK-0524B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia|Chronic Myelomonocytic Leukemia|de Novo Myelodysplastic Syndrome|Myelodysplastic Syndrome
Interventions: PROCEDURE: Bone Marrow Biopsy|BIOLOGICAL: Epoetin Alfa|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Providing Access to Cord Blood Units for Transplants
Status: WITHDRAWN
Conditions: Chronic Myelogous Leukemia/Other Leukemia|Acute Leukemias|MDS/MPS|Multiple Myeloma|Non-Hodgkin Lymphoma
Interventions: DRUG: Access to unlicensed cord blood units
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Brown Seaweed Tart Cherry Blend in Mild-moderate Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Brown seaweed and tart cherry blend|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dementia Caregiver Career Study
Status: COMPLETED
Conditions: Stress|Carer Stress Syndrome|Dementia|Alzheimer's Disease|Bereavement
Interventions: BEHAVIORAL: Resourcefulness Training|BEHAVIORAL: Biofeedback Training|BEHAVIORAL: Diversional Activites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AFP Specific T Cell Receptor Transduced T Cells Injection(C-TCR055) in Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Autologous C-TCR055
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zimbabwe Eyecare And Learning(ZEAL):Formative Research on Hyperopia and Educational Outcomes in Primary School Children
Status: COMPLETED
Conditions: Hyperopia|Long Sight
Interventions: DEVICE: Spectacles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients
Status: UNKNOWN
Conditions: Glioblastoma|Glioblastoma Multiforme|Glioma, Malignant
Interventions: BIOLOGICAL: EGFRvIII-specific hinge-optimized CD3 ζ-stimulatory/41BB-co-stimulatory Chimeric Antigen Receptor autologous T-lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENCOrafenib With Binimetinib in bRAF NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|BRAF V600E
Interventions: DRUG: Encorafenib 75 MG|DRUG: Binimetinib 15 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RFA for Small HCC With No-touch Technique Using Octopus Electrode
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: PROCEDURE: No-touch RFA|PROCEDURE: Conventional tumor puncture RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Emergency Care Action Plans for Infants With Medical Complexity
Status: NOT_YET_RECRUITING
Conditions: Children With Medical Complexity|Child, Only|Infant Morbidity|Infant Conditions|Utilization, Health Care|Emergencies|Chronic Condition
Interventions: OTHER: Emergency Care Action Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Evaluation of a New Palatal Implant for Treatment of Snoring and Obstructive Sleep Apnea (OSAS)
Status: COMPLETED
Conditions: Reduction of Initial AHI|Reduction of Initial Snoaring Index
Interventions: DEVICE: The IMD is a resilient palatal implant which is introduced through a stab incision into the palate.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of Levetiracetam Monotherapy in Patients With Newly Diagnosed Focal Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Partial Onset Seizures
Interventions: DRUG: Levetiracetam (LEV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Fluocinolone Acetonide Intravitreal Implants
Status: COMPLETED
Conditions: Noninfectious Posterior Uveitis
Interventions: DRUG: fluocinolone acetonide intravitreal implant|DRUG: Fluocinolone acetonide 2.1mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Placebo (for alirocumab)|DRUG: Alirocumab|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: NOT_YET_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: ARGX-119|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Septic Shock|Acute Respiratory Distress Syndrome
Interventions: DEVICE: PiCCO monitoring (PULSION)|PROCEDURE: central venous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study for Exploring the Efficacy of Naoxintong Capsules in the Treatment of Coronary Atherosclerotic Plaque on the Basis of Optimal Medical Therapy (Aspirin,Statins,Clopidogrel, Etc.): Stage One
Status: NOT_YET_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Naoxintong Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study to Evaluate Lower Dose of GSK2248761 in Antiretroviral Treatment-Naive HIV-1 Infected Adults.
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: GSK2248761|DRUG: Lopinavir/ritonavir|DRUG: HAART|DRUG: Placebo|DRUG: GSK2248761
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative FOLFIRINOX for Patients With Resectable Pancreatic Adenocarcinoma: A Pilot Study
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions: DRUG: FOLFIRINOX (oxaliplatin, leucovorin, irinotecan)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Recurrences of Atrial Arrhythmias and Their Impact on Late Recurrence After Pulmonary Vein Isolation With Pulsed Field Ablation of Paroxysmal Atrial Fibrillation
Status: RECRUITING
Conditions: Atrial Fibrillation Paroxysmal|Recurrence
Interventions: OTHER: Monitoring of paroxysmal atrial fibrillation recurrence after pulsed field catheter ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hybrid Versus Synthetic TOT for Treatment of SUI
Status: UNKNOWN
Conditions: Female Stress Incontinence
Interventions: PROCEDURE: Transobturator tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)
Status: COMPLETED
Conditions: Prostate Carcinoma Metastatic to the Bone|Castration Resistant Prostate Cancer
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secukinumab Safety and Efficacy in Juvenile Psoriatic Arthritis (JPsA) and Enthesitis-related Arthritis (ERA)
Status: COMPLETED
Conditions: Juvenile Psoriatic Arthritis|Enthesitis-related Arthritis
Interventions: DRUG: secukinumab|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Metastatic Gastrointestinal Carcinoid Tumor|Pulmonary Carcinoid Tumor|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Islet Cell Carcinoma
Interventions: DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody Plus Cyclophosphamide in Treating Patients With Metastatic Cancer
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: antibody therapy|BIOLOGICAL: biological therapy|BIOLOGICAL: muromonab-CD3|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: lithium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal HIV Disclosure to School Children: RCT of Family-based Intervention
Status: COMPLETED
Conditions: HIV|Disclosure
Interventions: BEHAVIORAL: Amagugu Counseling Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Triamcinolone Acetonide in Silicone-Filled Eyes as Adjunctive Treatment for Proliferative Vitreoretinopathy
Status: COMPLETED
Conditions: Proliferative Vitreoretinopathy
Interventions: DRUG: Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics of PXL770 After 4 Weeks of Treatment in Subjects With NAFLD
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver
Interventions: DRUG: PXL770|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Bortezomib in Treating Patients With Progressive or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: docetaxel|DRUG: bortezomib|OTHER: laboratory biomarker analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Clinical Excellence and Safety Evaluation of 4-channel Functional Electric Stimulator
Status: RECRUITING
Conditions: Dysphagia
Interventions: DEVICE: 4-channel Electrical Stimulation Device|DEVICE: 2-channel Electrical Stimulation Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Reconstructing Schoolyards With Greenery to Increase Schoolchildren's Physical Activity and Mitigate Climate Changes
Status: RECRUITING
Conditions: Physical Inactivity|Environmental Exposure|Mental Health Wellness 1
Interventions: BEHAVIORAL: Schoolyard reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
Status: NOT_YET_RECRUITING
Conditions: Rhabdomyolysis
Interventions: DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-D4010 in Healthy Subjects
Status: COMPLETED
Conditions: Cognitive Disorders
Interventions: DRUG: SUVN-D4010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sub-Ischial Socket for Transfemoral Amputation and Lower Mobility
Status: RECRUITING
Conditions: Transfemoral Amputation
Interventions: DEVICE: Northwestern University Flexible Subischial Suction Socket (NU-FlexSIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Magnesium on Anesthesia and Postoperative Analgesia After Surgical Removal of the Lower Third Molars.
Status: UNKNOWN
Conditions: Postoperative Pain|Third Molar|Postoperative Complications
Interventions: DIETARY_SUPPLEMENT: Magnesium tablet group|DIETARY_SUPPLEMENT: Placebo tablets group|DIETARY_SUPPLEMENT: Magnesium lozenge group|DIETARY_SUPPLEMENT: Placebo lozenges group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pregabalin is an Effective Treatment for Acute Postoperative Pain Following Spinal Surgery Without Major Side Effects
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Pregabalin|Spine Surgery|Adverse Reaction to Pregabalin
Interventions: DRUG: Pregabalin 25 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Barre Stretching Among Dental Hygiene Students
Status: NOT_YET_RECRUITING
Conditions: Musculoskeletal Disorders|Stress Management|Perceived Stress|Reported Stress|Perceived Pain|Reported Pain
Interventions: BEHAVIORAL: Barre Stretching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PII Trial of Docetaxel/Prednisone w/Sargramostim for HRPC
Status: TERMINATED
Conditions: Hormone Refractory Prostate Cancer
Interventions: DRUG: Sargramostim|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Recurrent Primary Central Nervous System Neoplasm|Refractory Malignant Solid Neoplasm|Refractory Primary Central Nervous System Neoplasm
Interventions: DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Sirolimus Albumin-bound Nanoparticles|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IM Versus 5-FU Versus IMI Versus MAL-PDT in Treatment of Actinic Keratosis
Status: UNKNOWN
Conditions: Keratosis, Actinic
Interventions: DRUG: Imiquimod|DRUG: 5-fluorouracil|DRUG: Ingenol mebutate|PROCEDURE: methylaminolevulinate photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alternating Ixazomib Citrate and Lenalidomide as Maintenance Therapy After Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasma Cell Myeloma|Transplant-Related Carcinoma
Interventions: DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of the Harmonic Scalpel in Neck Dissection
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Neck dissection with Harmonic scalpel|PROCEDURE: neck dissection with conventional hand-tie ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Dulaglutide|DRUG: Insulin glargine|DRUG: Metformin|DRUG: Sulfonylureas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Turkish Validation of Prosthesis Donning and Doffing Questionnaire
Status: COMPLETED
Conditions: Amputation; Traumatic, Leg, Lower
Interventions: OTHER: Satisfaction with Prosthesis -SATPRO|OTHER: Nottingham Health Profile-NHP|OTHER: Prosthesis donning and doffing questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Premature Infants
Status: COMPLETED
Conditions: Intraventricular Hemorrhage
Interventions: PROCEDURE: Umbilical Cord Milking|PROCEDURE: Delayed Cord Clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Venetoclax and Lintuzumab-Ac225 in AML Patients
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Relapsed Adult AML
Interventions: BIOLOGICAL: Lintuzumab-Ac225|DRUG: Venetoclax|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of RGB-286638 in Patients With Selected, Relapsed or Refractory Hematological Malignancies
Status: WITHDRAWN
Conditions: Hematological Malignancies
Interventions: DRUG: RGB-286638
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contribution of Urethral Sensory Feedback in Voiding Efficiency
Status: COMPLETED
Conditions: Urethral Anesthesia
Interventions: DRUG: lidocaine gel|OTHER: Plain aqueous gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet-rich Plasma With Topical Retinoids Versus Topical Retinoids Alone in Acne Vulgaris
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: OTHER: topical retinoids and platalet rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-dose Rifampicin for the Treatment of Tuberculous Meningitis: a Dose-finding Study
Status: COMPLETED
Conditions: Tuberculosis, Meningeal
Interventions: DRUG: Placebo|DRUG: Rifampicin|DRUG: Other TB drugs|DRUG: Adjuvant dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis
Status: RECRUITING
Conditions: Glaucoma|Eye Diseases|Cornea Disease
Interventions: PROCEDURE: Transscleral cyclphophotocoagulation using the Micropulse system ( IRIDEX IQ810 Laser systems, Mountain View, CA).|PROCEDURE: G-Probe transscleral cyclphophotocoagulation (Iris Medical Instruments, Montain View, CA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety of Laparoscopic ChOlecystectomy Performed by Trainee Surgeons With Different CHolangiographic Techniques
Status: UNKNOWN
Conditions: Cholecystitis; Gallstone
Interventions: PROCEDURE: IOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation
Status: COMPLETED
Conditions: COVID-19|Hypoxia
Interventions: DRUG: L-ascorbic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Intravitreal Conbercept for Exudative Circumscribed Choroidal Haemangioma
Status: UNKNOWN
Conditions: Circumscribed Choroidal Haemangioma
Interventions: DRUG: conbercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rewilding the Human Gut: Reintroduction of the Species Limosilactobacillus Reuteri
Status: COMPLETED
Conditions: Microbial Colonization
Interventions: OTHER: L Reuteri PB-W1 Strain|OTHER: L. Reuteri DSM20016T Strain|OTHER: Placebo|OTHER: Non-Industrialized-Type Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Detection of Colorectal Adenoma by Optical Enhancement Technology vs. High-Definition Colonoscopy
Status: UNKNOWN
Conditions: Colonic Polyps
Interventions: PROCEDURE: white light was used for colonoscopy withdrawal|PROCEDURE: OE mode was used for colonoscopy withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers
Status: RECRUITING
Conditions: Cholera|Cholera Vaccine Toxicity
Interventions: BIOLOGICAL: PanChol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transcranial Direct Current Stimulation for Postoperative Pain in Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Replacement
Interventions: DEVICE: tDCS|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 506U78 in Treating Patients With Recurrent or Refractory Cutaneous T-cell Lymphoma
Status: TERMINATED
Conditions: Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome
Interventions: DRUG: nelarabine|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Syntocinon for Prevention of Postpartum Hemorrhage in Cardiac Patients Undergoing Caesarean Section
Status: ENROLLING_BY_INVITATION
Conditions: Adverse Effect of Oxytocic Drugs
Interventions: DRUG: Syntocinon|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION