pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluate Pharmacokinetic/Pharmacodynamic and Safety/Tolerability of AYP-101 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Submental Fat
Interventions: DRUG: Polyene Phosphatidylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mulligan SNAG Technique in Individuals With Lumbar Intervertebral Disc Protrusion
Status: NOT_YET_RECRUITING
Conditions: Intervertebral Disc Protrusion
Interventions: OTHER: Mulligan SNAG mobilization tecnique|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches
Status: COMPLETED
Conditions: Migraine Headache
Interventions: DRUG: NPS 1776 (800 mg)|DRUG: PLACEBO|DRUG: NPS 1776 (400 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TY-302 in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Breast Cancer|Solid Tumor
Interventions: DRUG: TY-302: capsule, 25mg/50mg ; Tamoxifen: tablet,10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Advanced Practice Nurse-Led Telehealth on Readmissions
Status: UNKNOWN
Conditions: Acute Myocardial Infarction|Acute Coronary Syndrome
Interventions: OTHER: APN-led Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SP-8008
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Stroke
Interventions: DRUG: SP-8008 Prototype Capsule A|DRUG: SP-8008 Prototype Capsule B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SGN-30 and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: COMPLETED
Conditions: Adult Lymphocyte Depletion Hodgkin Lymphoma|Adult Lymphocyte Predominant Hodgkin Lymphoma|Adult Mixed Cellularity Hodgkin Lymphoma|Adult Nodular Sclerosis Hodgkin Lymphoma|Recurrent Adult Hodgkin Lymphoma
Interventions: BIOLOGICAL: monoclonal antibody SGN-30|OTHER: placebo|DRUG: vinorelbine tartrate|DRUG: pegylated liposomal doxorubicin hydrochloride|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease
Status: UNKNOWN
Conditions: Acute Coronary Syndromes
Interventions: DEVICE: High dose rapamycin stent|DEVICE: Low dose rapamycin stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in R/R DLBCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: BIOLOGICAL: Epcoritamab|DRUG: Investigator's Choice Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blind Elderly Melatonin Treatment Study
Status: TERMINATED
Conditions: Blindness
Interventions: BIOLOGICAL: Melatonin|BIOLOGICAL: Melatonin|BIOLOGICAL: Melatonin|BIOLOGICAL: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oestradiol Supplementation in Luteal Long Agonist Fresh In Vitro Fertilization/Intra Cytoplasmic Sperm Injection ( IVF/ICSI) Cycle .
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: Estradiol Valerate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Cukurova University Faculty of Medicine Non-interventional Clinical Research Institutional Ethics Committe
Status: COMPLETED
Conditions: Menopause|Sleep|Fatigue|Therapeutic Touch
Interventions: BEHAVIORAL: Therapeutic Touch|OTHER: Sham Therapeutic Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: GSK5733584
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation Therapy in Anorexia Nervosa
Status: COMPLETED
Conditions: Teenager|Young Adult|Hospitalized|Anorexia Nervosa (DSM-IV Revised Criteria)
Interventions: BEHAVIORAL: Cognitive Remediation Therapy|BEHAVIORAL: Sham Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Automated Closed-Loop Ventilation Reduce the DRiving Pressure Levels in Patients With ARDS
Status: TERMINATED
Conditions: ARDS
Interventions: DEVICE: INTELLiVENT-ASV|OTHER: Conventional lung protective ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid Malignancies
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: MP-470|DRUG: amuvatinib (MP-470)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS for the Treatment of Pain and Respiratory Function Following Mastopexy With Augmentation
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Respiratory Complication
Interventions: DEVICE: Experimental: Experimental group|DEVICE: Sham Comparator: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strip Meniscometry in Dry Eye Evaluation
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Disease
Interventions: DIAGNOSTIC_TEST: Central visual acuity|DIAGNOSTIC_TEST: Intraocular pressure measurement|DIAGNOSTIC_TEST: Slit lamp examination|DIAGNOSTIC_TEST: Refraction and keratometry|DIAGNOSTIC_TEST: Optical biometry|DIAGNOSTIC_TEST: Strip meniscometry (SM)|DIAGNOSTIC_TEST: Lid Parallel Conjunctival Folds test (LIPCOF)|DIAGNOSTIC_TEST: Staining of the ocular surface with fluorescein|DIAGNOSTIC_TEST: Tear break up time test (TBUT)|OTHER: Ocular Surface Disease Index questionnaire (OSDI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Integrated Treatment for Comorbid PTSD and Substance Abuse in Adolescents
Status: COMPLETED
Conditions: Substance Abuse|Traumatic Stress
Interventions: BEHAVIORAL: Trauma-focused Substance Abuse Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REcovery of Left Ventricular Dysfunction in CAncer Patients (RECAP Trial)
Status: COMPLETED
Conditions: Heart Failure|Cancer Treatment Induced Left Ventricular Dysfunction
Interventions: DEVICE: Echocardiograms|DEVICE: Electrocardiogram|BEHAVIORAL: Symptom Questionnaire|BEHAVIORAL: Telephone Follow-Up
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Suboccipital Inhibition Technique in Patients With Mechanical Neck Pain
Status: UNKNOWN
Conditions: Neck Pain|Myofascial Pain
Interventions: OTHER: Suboccipital inhibition technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: fish oil capsules|DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTTAPE : Observatory on the Use of New Therapies (LED Photobiomodulation, Radiofrequency, Laser and Injectable Hyaluronic Acid) in the Treatment of Women's Pelvic-perineal Pathologies After Failure, Partial or Total, of First-line Medical Treatment
Status: COMPLETED
Conditions: Pelvic-perineal Pathology
Interventions: OTHER: None. This is a non-interventional observational study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Glycopyrronium in Subjects With Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Hyperhidrosis
Interventions: DRUG: glycopyrronium Topical Wipes|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Ultrasound-assessed Quadriceps Muscle Mass and Baseline Whole-body Densitometry Muscle Index in the Post-cancer Population (JUMP Research II)
Status: RECRUITING
Conditions: Cancer|Post-cancer|Hematology
Interventions: OTHER: JUMP group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Effect of Tracleer on Tourniquet-associated Hypertension
Status: UNKNOWN
Conditions: Tourniquets|Hypertension|Bosentan
Interventions: DRUG: Tracleer 125Mg Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults.
Status: COMPLETED
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: Low dose Ebola Zaire vaccine (Ad5-EBOV)|BIOLOGICAL: High dose Ebola Zaire vaccine (Ad5-EBOV)|BIOLOGICAL: placebo (one dose)|BIOLOGICAL: placebo (two doses)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury.
Status: RECRUITING
Conditions: Sepsis|Septic Shock|Acute Kidney Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacist Management of Attention Deficit Hyperactivity Disorder Medication Refill Requests
Status: COMPLETED
Conditions: Attention-deficit Hyperactivity
Interventions: OTHER: Pharmacist Care|OTHER: Primary Care Physician Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access
Status: COMPLETED
Conditions: Stroke|Intracranial Hypotension|Cerebral Edema
Interventions: DEVICE: Intraosseous|DRUG: Hypertonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) Versus Platinum-Based Chemotherapy for Participants With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Advanced or Metastatic Non-Small Cell Lung Cancer (MK-3475-042/KEYNOTE-042)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: pembrolizumab|DRUG: carboplatin|DRUG: paclitaxel|DRUG: pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LCP-Tacro vs. Azathioprine for the Treatment of Autoimmune Hepatitis
Status: TERMINATED
Conditions: Autoimmune Hepatitis
Interventions: DRUG: LCP-Tacro (tacrolimus)|DRUG: Azathioprine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Transcatheter Patent Foramen Ovale Closure for Migraine
Status: COMPLETED
Conditions: Foramen Ovale, Patent|Migraine
Interventions: DEVICE: transcatheter patent foreman ovale closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
Status: RECRUITING
Conditions: Lymphoblastic Lymphoma, Childhood
Interventions: DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Daunorubicin|DRUG: Doxorubicin|DRUG: Ifosfamide|DRUG: 6-Mercaptopurine|DRUG: Methotrexate|DRUG: PEG asparaginase|DRUG: Prednisone|DRUG: Prednisolone|DRUG: Thioguanine|DRUG: Vincristine|DRUG: Vindesine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: DRUG: Aminolevulinic Acid (ALA)|DEVICE: Environ Cosmetic Roller|DEVICE: BLU-U IIlluminator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo-Controlled, Double-Blind, Crossover Study to Evaluate the Effects of Three Doses of the Dietary Supplement oréVida™ on Alertness, Attention and Concentration in Healthy Men and Women
Status: COMPLETED
Conditions: Attention|Memory|Alertness
Interventions: DIETARY_SUPPLEMENT: oréVida™|DIETARY_SUPPLEMENT: oréVida™|DIETARY_SUPPLEMENT: oréVida™|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Using Continuous Glucose Monitoring to Detect and Intervene on Maintenance Factors for Trans-diagnostic Binge Eating Pathology
Status: COMPLETED
Conditions: Bulimia Nervosa|Binge Eating
Interventions: BEHAVIORAL: CBT with smartphone application SenseSupport
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy Volunteers
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Corticobasal Degeneration
Interventions: DRUG: Flortaucipir F18|PROCEDURE: Brain PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A New Optical Sweat Test Method Based on a Citric Acid-derived Multi-halide Sensor
Status: TERMINATED
Conditions: Cystic Fibrosis
Interventions: DIAGNOSTIC_TEST: Measurement of Sweat Chloride and Sweat Bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Lapaquistat acetate|DRUG: Lapaquistat acetate and atorvastatin|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Lenalidomide and Intravesical BCG for Therapy of Bladder Cancer
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: Bacille Calmette-Guerrin (BCG)|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Access to Extended Release Guanfacine HCl for Subjects Who Participated in Studies SPD503-315 or SPD503-316 in Europe
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: DRUG: Extended-release Guanfacine HCl (Intuniv, SPD503)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Response to Neo-adjuvant Chemotherapy for Patients With a Locally Advanced Breast Cancer With 3D Elastography (Shear Wave),
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: 3D Shear Wave Elastography (SWE)|BIOLOGICAL: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Accu-Chek 360 in Veterans With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Targeted Self-Monitoring Of Blood Glucose (SMBG)|OTHER: Provider Training|OTHER: Patient Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feeding Trial to Determine How Combinations of Different Dietary Bioactive Ingredients Influence High Density Lipoprotein (HDL) Metabolism
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Krill Oil|DIETARY_SUPPLEMENT: Lutein|DIETARY_SUPPLEMENT: Nicotinic acid|DIETARY_SUPPLEMENT: Dairy phospholipids|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KRX-0502 (Ferric Citrate) for the Treatment of IDA in Adult Subjects With NDD-CKD
Status: COMPLETED
Conditions: Anemia of Chronic Kidney Disease
Interventions: DRUG: ferric citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly
Status: COMPLETED
Conditions: Alzheimer's Disease|Mild Cognitive Impairment|Age-Related Cognitive Decline|Dementia
Interventions: DEVICE: BrainPalTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial to Reduce Harm From Tobacco
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: E-cigarette free access|BEHAVIORAL: E-cigarette/NRT/Zyban/Chantix Choice|BEHAVIORAL: Outcome Incentive arm|BEHAVIORAL: Loss framing incentive arm|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?
Status: COMPLETED
Conditions: Choledocholithiasis With Cholecystitis|Biliary Stones
Interventions: PROCEDURE: Laproscopic cholecystectomy (LC)|PROCEDURE: Endoscopic Retrograde Cholangiopancreatography (ERCP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Safety, Pharmacokinetics and Haemodynamic Effect of a Slow Release Oral Formulation of Milrinone
Status: COMPLETED
Conditions: Healthy|Heart Failure
Interventions: DRUG: Milrinone 6mg|DRUG: milrinone 10mg ER|DRUG: milrinone 14mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice
Status: COMPLETED
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: retapamulin|DRUG: Retapamulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study for Combinational Treatment of DaRT and Check Point Inhibitor for Recurrent Unresectable or mHNSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Skin Cancer|Metastatic Head-and-neck Squamous-cell Carcinoma
Interventions: DEVICE: Diffusing Alpha Radiation Emitters Therapy (DaRT)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prayer on Dyspnea Severity, Anxiety and Spiritual Well-Being in Individuals With COPD
Status: COMPLETED
Conditions: COPD
Interventions: OTHER: A prayer concert will be held for the participants.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of SYHX1901 Tablets in Severe Alopecia Areata Patients
Status: NOT_YET_RECRUITING
Conditions: Severe Alopecia Areata
Interventions: DRUG: SYHX1901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate Drug-drug Interactions and Safety Between "BR1015-1" and "BR1015-2" in Healthy Volunteers
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: BR1015-1|DRUG: BR1015-2|DRUG: BR1015-1 + BR1015-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors
Status: COMPLETED
Conditions: Childhood Germ Cell Tumor|Ovarian Cancer|Teratoma
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|DRUG: paclitaxel|DRUG: thiotepa|PROCEDURE: autologous hematopoietic stem cell transplantation|DRUG: Mesna|BIOLOGICAL: filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Roux-En-Y Gastric Bypass|OTHER: Low-calorie Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03826)
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Desloratadine (Clarinex)|DRUG: Cetirizine (Zyrtec)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Compare Oral Absorption of YM060 Between Orally-disintegrating Tablet (Without Water) and Conventional Tablet
Status: COMPLETED
Conditions: Healthy|Plasma Concentration of YM060
Interventions: DRUG: YM060
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Dopamine Versus Norepinephrine Under General Anesthesia
Status: COMPLETED
Conditions: Anesthesia|Infant|Congenital Heart Disease|Hemodynamic Instability
Interventions: DRUG: norepinephrine|DRUG: dopamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Approach for Promoting Physical Activity in Mayo Clinic Physicians
Status: COMPLETED
Conditions: Weight|Well Being
Interventions: OTHER: GRUVE accelerometer (MUVE, inc.)|OTHER: walking workstation|PROCEDURE: exercise counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pectoralis and Serratus Muscle Blocks
Status: COMPLETED
Conditions: Post Operative Pain Control
Interventions: DRUG: Exparel 266 MG Per 20 ML Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute and Residual Effects of Caffeinated Beer
Status: COMPLETED
Conditions: Neurobehavioral Manifestations|Drug Related Sleep Disturbance|Alcohol Intoxication
Interventions: DRUG: Caffeinated Alcoholic Beer|OTHER: Non-Caffeinated Alcoholic Beer|DRUG: Caffeinated Non-Alcoholic Beer|OTHER: Non-Caffeinated, Non-Alcoholic Beer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Mucolytic Solution Before Upper Endoscopy
Status: UNKNOWN
Conditions: Gastroscopy; Gastric Cancer
Interventions: DRUG: Administration of mucolytic solution before upper endoscopy (Espumisan, ACC long)|DRUG: Administration of water before upper endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI
Status: RECRUITING
Conditions: ST Elevation Myocardial Infarction
Interventions: DEVICE: Primary PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Orbital Compression Surgery and Strabismus Surgery for Thyroid Associated Ophthalmopathy
Status: UNKNOWN
Conditions: Thyroid Associated Ophthalmopathy
Interventions: PROCEDURE: combination of orbital compression surgery and strabismus surgery|PROCEDURE: orbital compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: aldesleukin|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exclusive Human-milk in Preterm NEOnates and Early VASCular Aging Risk Factors (NEOVASC)
Status: RECRUITING
Conditions: Prematurity|Vascular Aging
Interventions: DIETARY_SUPPLEMENT: Humavant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 4-session Metacognitive Training in Chinese Adult Outpatients With Schizophrenia Spectrum Disorders and Major Depressive Disorder
Status: COMPLETED
Conditions: Delusions|Depression
Interventions: OTHER: Metacognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TCR-T Cells for the Treatment NY-ESO-1-positive Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumors
Interventions: BIOLOGICAL: TCR-T cells|DRUG: Fludarabine|DRUG: Cyclophosphamide Capsules|DRUG: Albumin-bound paclitaxel|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Evaluate the Safety, Efficacy and Pharmacokinetics/Pharmacodynamics of BAYQ3939 in Patients With Bacterial Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Ciprofloxacin (Cipro, BAYQ3939)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIVACOR Trial: Minimally Invasive LIVer And Simultaneous COlorectal Resection
Status: UNKNOWN
Conditions: Colorectal Neoplasms Malignant|Neoplasm Metastasis
Interventions: PROCEDURE: Minimally invasive simultaneous resection|PROCEDURE: Minimally invasive two-stage resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement
Status: TERMINATED
Conditions: Aortic Stenosis
Interventions: DEVICE: Transcaval closure device (TCD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Topical Mesalazine Sustained-Release Tablets in Crohn's Disease Patients With Oral Ulcer
Status: WITHDRAWN
Conditions: Crohn's Disease|Oral Ulcer
Interventions: DRUG: Mesalazine Sustained-Release Tablets|DRUG: Riboflavin Sodium Phosphate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Properties of BIOD-123 and BIOD-125 Compared to Humalog® in Subjects With Type 1 Diabetes Including Assessments of Injection Site Toleration
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: BIOD-123|DRUG: BIOD-125|DRUG: Humalog
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma.
Status: COMPLETED
Conditions: Medullary Thyroid Carcinoma|Nodular Goiter
Interventions: DIAGNOSTIC_TEST: Fine Needle Aspiration Cytology (FNAC) procedure+calcitonin measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis
Status: RECRUITING
Conditions: Cancer, Appendiceal|ColoRectal Cancer
Interventions: DRUG: Mitomycin c|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Scapular Stabilization Exercises Versus Eccentric Muscle Energy Techniques in Patients With Upper Crossed Syndrome
Status: RECRUITING
Conditions: Upper Crossed Syndrome
Interventions: OTHER: Protocol of Scapular Stabilization Exercises;|OTHER: Protocol of Muscle Energy technique;
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Counting On U: Towards Better Mental Health
Status: COMPLETED
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Mental Health First Aid and Relationship Building Training|BEHAVIORAL: Mental Health First Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Magnesium Sulfate Bolus in Pediatric Patients With Bronchiolitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchiolitis, Viral
Interventions: DRUG: Magnesium Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Pegylated Interferon Lambda Versus Pegylated Interferon Alfa, Plus Ribavirin in Subjects With Hepatitis C
Status: WITHDRAWN
Conditions: Hepatitis C Virus (HCV)
Interventions: BIOLOGICAL: Pegylated Interferon Lambda|BIOLOGICAL: Pegylated Interferon Alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Non-Invasive Automated Fractional Flow Reserve Software System in Patients With Coronary Artery Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Stable Angina, Unstable Angina, NSTEMI
Interventions: OTHER: Collecting invasive FFR measurements.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of ADHEAR, a Non-Implantable Bone Conduction Hearing System, in Children With Single Sided Deafness and/or Conductive Hearing Loss
Status: UNKNOWN
Conditions: Conductive Hearing Loss|Single Sided Deafness
Interventions: DEVICE: ADHEAR Audio Processor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib Plus Rituximab for cGVHD Following Allo-SCT
Status: TERMINATED
Conditions: Chronic Graft-versus-host-disease
Interventions: DRUG: Ibrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment for Treatment-Experienced, HIV-Infected People
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Enfuvirtide|DRUG: Raltegravir|DRUG: Darunavir|DRUG: Tipranavir|DRUG: Etravirine|DRUG: Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retention of Computer Aided Design and Computer Aided Manufacturing Titanium Versus Co/Cr Single Dentures.
Status: UNKNOWN
Conditions: Edentulous Mouth
Interventions: DEVICE: CAD/CAM titanium denture base|DEVICE: CAD/CAM cobalt/chromium denture bases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Crossover Bioequivalence Study of Quetiapine Fumarate 25 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Bipolar I Disorder
Interventions: DRUG: Quetiapine Fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bleb Vascularity Change After Subconjunctival Injection Bevacizumab
Status: UNKNOWN
Conditions: Bleb Vascularity|Conjunctival Scarring
Interventions: DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Effectiveness and Safety of Extracorporeal Shock Wave Therapy (ESWT) for Treatment of Painful Heel Syndrome
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: DEVICE: Duolith SD1|DEVICE: Sham Duolith SD1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo IGF-1R Molecular Imaging Using [68Ga]- Labelling Anti-IGF-1R Affibody Molecule
Status: UNKNOWN
Conditions: Molecular Imaging
Interventions: RADIATION: 68Ga-NODAGA-ZIGF-1R:4：40
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Prevent and Improve Sexual Health Concerns for People With Breast Cancer
Status: RECRUITING
Conditions: Improve Sexual Health|Improve Vulvovaginal Health
Interventions: OTHER: questionnaires|OTHER: moisturizers|OTHER: moisturizers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint
Status: TERMINATED
Conditions: Arthritis Multiple Joint
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Steroid - Triamcinolone Acetonide|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Scapular Clock Exercises in Scapular Dyskinesia in Post-Operative Open Heart Surgery Patients
Status: UNKNOWN
Conditions: Scapular Dyskinesis
Interventions: OTHER: Scapular clock exercises|OTHER: Stretching and strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of miRNAs in CVD and Periodontitis
Status: COMPLETED
Conditions: Cardiovascular Diseases|Periodontal Diseases
Interventions: OTHER: Observation of Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetics of Hypertension Associated Treatments (GenHAT)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Hypertension|Coronary Disease|Myocardial Infarction
Interventions: DRUG: Chlorthalidone|DRUG: Lisinopril|DRUG: Amlodipine|DRUG: Doxazosin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-operative Vabysmo in Patients With Non-clearing Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy
Status: ENROLLING_BY_INVITATION
Conditions: Diabetic Retinopathy|Vitreous Hemorrhage Due to Diabetes Mellitus
Interventions: DRUG: Faricimab Injection|DRUG: sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VItamin C in Thermal injuRY: The VICToRY Trial
Status: RECRUITING
Conditions: Shock|Thermal Burn
Interventions: DRUG: Ascorbic Acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LCI-GU-URO-CRI-001: Crizotinib in Patients With c-MET or RON-Positive Metastatic Urothelial Cancer
Status: TERMINATED
Conditions: Urinary Bladder Neoplasms|Ureteral Neoplasms|Urethral Neoplasms
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of CB1 Antagonist/Reverse Agonist Rimonabant on Walking Abilities in Incomplete Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DRUG: Rimonabant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peak Inspiratory Flow and Dry Powder Inhaler Performance in COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Trelegy Ellipta 100/62.5/25Mcg Inh 30D|DRUG: Ventolin 90Mcg/Actuation Inhalation Aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing 2 Different Strategies For Management of Subjects With Plaque Psoriasis Who Have Responded to Etanercept
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: etanercept|DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib to Prevent Colorectal Cancer in Patients Who Have Undergone Surgery to Remove Polyps
Status: COMPLETED
Conditions: Colon Cancer|Rectal Cancer
Interventions: DRUG: celecoxib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of DE-104 Ophthalmic Solution to Treat Open-angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DE-104 medium concentration|DRUG: DE-104 high concentration|DRUG: Placebo|DRUG: 0.005% latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Genotype-guided Study of Irinotecan Administered in Combination With 5-fluorouracil/Leucovorin (FOLFIRI) and Bevacizumab in Advanced Colorectal Cancer Patients
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI, Avastin, Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-087/KEYNOTE-087)
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: BIOLOGICAL: pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Combined With Sintilimab Plus Bevacizumab Biosimilar in Patients With Advanced Hepatocellular Carcinoma (TASK-02)
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Sintilimab|COMBINATION_PRODUCT: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Virtual BASRD Reality Training Versus Conservative Treatment In Chronic Hemipretic Stroke Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: COMBINATION_PRODUCT: Exp Group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma
Status: UNKNOWN
Conditions: Sarcoma,Soft Tissue|Extremity|Trunk|Anlotinib|Intensity-modulated Radiotherapy|Major Wound Complications
Interventions: DRUG: Anlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Node-sparing Radiotherapy Combined With Total Neoadjuvant CAPOX and Sintilimab for MSS Middle and Low Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: RADIATION: node-sparing short-course radiotherapy|DRUG: Sintilimab|DRUG: Capecitabine|DRUG: Oxaliplatin|PROCEDURE: TME surgery|PROCEDURE: watch and wait
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery Occlusion
Status: COMPLETED
Conditions: Central Retinal Artery Occlusion
Interventions: DRUG: Alteplase|DRUG: acetylsalicylic acid|DRUG: Placebo Oral Tablet|DRUG: placebo IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compassion Training and Mindfulness Training for Social Well-Being and Mental Health
Status: COMPLETED
Conditions: Anxiety|Depression|Stress|Burnout|Emotion Regulation|Social Acceptance|Loneliness|Compassion
Interventions: BEHAVIORAL: Compassion Cultivation Training (CCT)|BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Yoga-based Physical Therapy for Individuals With Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: OTHER: Yoga-based physical therapy group|OTHER: Seated Rest|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking Insulin Alone or With Other Oral Antidiabetic Agents
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin|DRUG: Insulin glargine (HOE901)|DRUG: Placebo|DRUG: Oral Antidiabetes Drugs (OADs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Altitude Illness With Non-steroidal Anti-inflammatory Study (PAINS)
Status: COMPLETED
Conditions: Altitude Sickness
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION