pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomised Study of Docosahexaenoic Acid (DHA) in Metastatic Breast Cancer
Status: TERMINATED
Conditions: Metastatic Breast Cancer|Progesterone Receptor Positive Tumor|Estrogen Receptor Positive Tumor|HER-2 Negative Tumor
Interventions: DIETARY_SUPPLEMENT: Dietary supplementation with fish oil.|DIETARY_SUPPLEMENT: Dietary supplementation with vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of Thymosin Beta 4 in Patients With Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: NL005 Middle Dose|DRUG: NL005 High Dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tipepidine in Children With Attention Deficit/Hyperactivity Disorder (AD/HD): a Double-blind, Placebo-controlled Trial
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity Disease|Hyperkinesis|Attention Deficit and Disruptive Behavior Disorders
Interventions: DRUG: Tipepidine Hibenzate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FACILE: FeAsibility of First-line riboCIclib in oLdEr Patients With Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Ribociclib|DRUG: Aromatase Inhibitors, non steroideal|DRUG: LHRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Albiglutide Glucose Clamp Study in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|BIOLOGICAL: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: OTHER: Lixisenatide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion
Status: RECRUITING
Conditions: Stroke, Acute|Neuroprotection|Ischemic Conditioning
Interventions: PROCEDURE: Direct Ischemic Post-conditioning|PROCEDURE: Endovascular therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Ceftaroline in Paediatrics With Late-Onset Sepsis
Status: TERMINATED
Conditions: Late-onset Sepsis
Interventions: DRUG: Ceftaroline Fosamil|DRUG: Ampicillin|DRUG: Aminoglycoside
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Interleukin-2 Followed by Intermittent Low Dose Temozolomide in Patients With Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Interleukin-2|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 5% Topical Ibuprofen (IBU) for Ankle Sprain
Status: COMPLETED
Conditions: Ankle Injuries
Interventions: DRUG: Topical IBU twice daily|DRUG: Placebo twice daily|DRUG: Topical IBU three times daily|DRUG: Placebo three times daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of AERAS-456 Vaccine for Tuberculosis
Status: COMPLETED
Conditions: Latent Tuberculosis|Latent Tuberculosis Bacteriology and Histology Unknown
Interventions: BIOLOGICAL: H56:IC31
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanism and Early Intervention Research on ALI During Emergence Surgery of Acute Stanford A Aortic Dissection
Status: UNKNOWN
Conditions: Acute Aortic Dissection
Interventions: DRUG: Ulinastatin|DRUG: Tranexamic acid|DRUG: Edaravone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Prospective, Multi-center Trial to Assess an Everolimus-Eluting Coronary Stent System (PROMUS Element™)
Status: COMPLETED
Conditions: Atherosclerosis|Coronary Artery Disease
Interventions: DEVICE: PROMUS Element™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Ribociclib and Palbociclib on Tumor and Blood Characteristics in Patients With Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Advanced Breast Adenocarcinoma|Advanced HER2-Negative Breast Carcinoma|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Hormone Receptor-Positive Breast Carcinoma|Metastatic Breast Adenocarcinoma|Metastatic HER2-Negative Breast Carcinoma|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: OTHER: Best Practice|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Quality of Life After Treatment for Bladder Cancer: The Bladder Cancer Survivorship Study
Status: RECRUITING
Conditions: Stage 0a Bladder Cancer AJCC v8|Stage 0is Bladder Cancer AJCC v8|Stage I Bladder Cancer AJCC v8|Stage II Bladder Cancer AJCC v8|Stage IIIA Bladder Cancer AJCC v8
Interventions: OTHER: Non-Interventional Study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability of Baclofen for Alcohol Dependence
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: baclofen|DRUG: placebo|BEHAVIORAL: BRENDA counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ultrasound-Guided Erector Spinae Plane Block for Postoperative Pain Control in Open Knee Surgeries
Status: NOT_YET_RECRUITING
Conditions: Knee Injuries
Interventions: PROCEDURE: erector spinea plane block|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Permission to Collect Blood Over Time for Research
Status: TERMINATED
Conditions: Pancreatic Cancer|Gastrointestinal Neoplasms|Colon Rectal Cancer Adenocarcinoma|Esophageal Cancer|Gall Bladder Cancer|Gastric (Stomach) Cancer|Gastrooesophageal Cancer|Gastrointestinal Stromal Tumor (GIST)|Hepatobiliary Neoplasm|Liver Carcinoma|Gallbladder Carcinoma|Bile Duct Carcinoma|Carcinoma of the Large Intestine|Anal Cancer
Interventions: PROCEDURE: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Foley Catheter vs a Self-contained Valved Urinary Catheter
Status: COMPLETED
Conditions: Catheter-Related Infections|Urinary Tract Infections|Urogynecologic Surgery
Interventions: DEVICE: Foley Catheter vs Self-Contained Valved Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
Status: RECRUITING
Conditions: Traumatic Brain Injury|Insomnia|Depression|Post-traumatic Stress|Sleep|Memory Impairment|Cognitive Behavioral Therapy|Concussion, Brain|Head Injury|Brain Injury Traumatic Mild
Interventions: BEHAVIORAL: Mindfulness-based treatment for insomnia (MBTI)|BEHAVIORAL: Cognitive behavioral therapy for insomnia (CBT-I)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Durvalumab|OTHER: Placebo|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Pemetrexed|DRUG: Paclitaxel|DRUG: Gemcitabine|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia
Status: TERMINATED
Conditions: HIV Infections|Hyperlipidemia
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children
Status: COMPLETED
Conditions: Constipation|Faecal Impaction
Interventions: DRUG: Polyethylene glycol with electrolytes|DEVICE: Polyethylene glycol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ranolazine in Diastolic Heart Failure
Status: COMPLETED
Conditions: Diastolic Heart Failure
Interventions: DRUG: Ranolazine|OTHER: Saline 0.9% and placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: OTHER: TIL|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Interleukin-2|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TACE Combinated With Sorafenib in Treating Patients With Unresectable Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: PHENYTOIN/SORAFENIB [VA Drug Interaction]|Carcinoma, Hepatocellular
Interventions: PROCEDURE: TACE|DRUG: sorafenib combined with TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing Delirium Through Music in Critically Ill Older Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Intensive Care Unit Delirium|Pain|Anxiety|Intensive Care Acquired Cognitive Impairment
Interventions: OTHER: Slow Tempo Music|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multisystem Inflammatory Syndrome In Children at Sohag University Hospital
Status: UNKNOWN
Conditions: Multisystem Inflammatory Syndrome in Children
Interventions: DIAGNOSTIC_TEST: CBC, ESR ,CRP,Liver Function ,renal function ,ABG,Na,K,D-dimmer ,cardiac enzyme,ferritin ,blood and urine culture in negative cases
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post Extubation Delirium and End-tidal Sevoflurane Concentration
Status: COMPLETED
Conditions: Delirium on Emergence
Interventions: DRUG: sevoflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Pharmacokinetics of AGN-190168 in Subjects With Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: AGN-190168 Formulation 1|DRUG: AGN-190168 Formulation 2|DRUG: tazarotene gel 0.1%|DRUG: tazarotene cream 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of an Automatic Toothbrush
Status: COMPLETED
Conditions: Dental Plaque
Interventions: OTHER: Automatic toothbrush with nylon bristle|OTHER: Automatic toothbrush with silicone bristle|OTHER: Manual toothbrush used for 2 minutes|OTHER: Manual toothbrush used for 45 seconds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Move for Surgery (MFS): Evaluating the Use of Wearable Technology for Preconditioning Before Thoracic Surgery
Status: COMPLETED
Conditions: Preconditioning|Lung Cancer, Nonsmall Cell
Interventions: OTHER: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomized, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Treatment of Physician's Choice in Subjects With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Eribulin|DRUG: TPC -Vinorelbine,Gemcitabine,Docetaxel, and Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma|Intrahepatic Cholangiocarcinoma|Liver Metastases
Interventions: DRUG: MIV-818 (fostroxacitabine bralpamide) + pembrolizumab|DRUG: MIV-818 (fostroxacitabine bralpamide) + lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms Underlying Postoperative Insulin Resistance and Inflammation
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: carbohydrate drink|PROCEDURE: Muscle biopsy|PROCEDURE: Blood sampling|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acute Effects of Oxygen Supplementation Among IPF Patients
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Oxygen 40 %|DRUG: Medical air (sham O2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant PVX-410 Vaccine and Durvalumab in Stage II/III Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: BIOLOGICAL: PVX-410|BIOLOGICAL: Durvalumab|DRUG: Hiltonol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of B244 Delivered as a Topical Spray to Assess Safety in Pediatric Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Eczema|Atopic Dermatitis
Interventions: DRUG: Experimental: B244
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung Ultrasound Assisting Weaning in Difficult-to-wean Patients
Status: UNKNOWN
Conditions: Difficult-to-wean Adult Patients
Interventions: OTHER: Abolish Lung Sliding|OTHER: Normal Lung Ultrasound|OTHER: Pulmonary Interstitial Syndrome|OTHER: Asymmetrical Lung Ultrasound|OTHER: Simple Pleural Effusion|OTHER: Complex Pleural Effusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ABX Plus Cisplatin Versus Gemcitabine Plus Cisplatin in Triple Negative Breast Cancer (TNBC)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: ABX, cisplatin|DRUG: Gemcitabine, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Connections and Blood Pressure
Status: COMPLETED
Conditions: Hypertension|Mild Cognitive Impairment
Interventions: BEHAVIORAL: Mindfulness and DASH Diet Education|BEHAVIORAL: Education group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: ST-segment Elevation Myocardial Infarction (STEMI)
Interventions: OTHER: Morning aerobic exercise|OTHER: Evening aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Breastfeeding Training Given to Mothers With Vaginal Birth by Motivational Interview Technique
Status: RECRUITING
Conditions: Breastfeeding
Interventions: BEHAVIORAL: Breastfeeding education based on motivational interviewing technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single-cell Sequencing of BLF to Guide the Treatment of Radiation Pneumonitis or Immune Checkpoint Inhibitor Pneumonitis
Status: RECRUITING
Conditions: Pneumonitis
Interventions: GENETIC: single-cell sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fluid Management by Pleth Variability Index on Acute Kidney Injury in Obese Patients
Status: COMPLETED
Conditions: Laparoscopic Colorectal Surgery|Acute Kidney Injury
Interventions: OTHER: pulse variability index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxycodone Hydrochloride Injection in the Postoperative Pain Relieving Treatment
Status: COMPLETED
Conditions: Other Acute Postoperative Pain
Interventions: DRUG: Oxycodone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Sickle Cell Anemia|Osteonecrosis|Ischemic Necrosis|Avascular Necrosis
Interventions: DRUG: Alendronate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Blood Pressure for the prevenTIon of Major vAscuLar Events in Patients With DIABETES Mellitus (OPTIMAL-DIABETES)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|High Blood Pressure|Cardiovascular Diseases|Cognitive Impairment
Interventions: DRUG: Intensive Control of Systolic Blood Pressure (SBP)|DRUG: Standard control of Systolic Blood Pressure (SBP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide for Migraine: A Dose Finding Study
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: metoclopramide|DRUG: metoclopramide|DRUG: metoclopramide|DRUG: Diphenhydramine 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency
Status: RECRUITING
Conditions: Nicotine Vaping|Nicotine Dependence|Nicotine Addiction
Interventions: COMBINATION_PRODUCT: e-liquid 1|COMBINATION_PRODUCT: e-liquid 2|COMBINATION_PRODUCT: e-liquid 3|COMBINATION_PRODUCT: e-liquid 4|COMBINATION_PRODUCT: e-liquid 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Core Stability Exercise on Isolated Patellofemoral Osteoarthritis.
Status: COMPLETED
Conditions: Chondromalacia Patellae
Interventions: OTHER: a traditional therapeutic knee rehabilitation program|OTHER: core stability exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obesity Surgery During 2020 Italian Pandemic
Status: UNKNOWN
Conditions: Bariatric Surgery Candidate|Covid19|Complication of Surgical Procedure|Pneumonia, Viral|Viral Infection|Obesity, Morbid|Safety Issues|Readmission
Interventions: PROCEDURE: Bariatric procedures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Different Surgical Methods to Treat Obesity
Status: COMPLETED
Conditions: Obesity|Type 2 Diabetes|Insulin Sensitivity
Interventions: PROCEDURE: Omentectomy|PROCEDURE: Gastric bypass operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Endoscopic Subureteral Injection for Vesicoureteral Reflux in Adults With Decreased Bladder Compliance
Status: COMPLETED
Conditions: Vesicoureteral Reflux
Interventions: PROCEDURE: Endoscopic subureteric injection
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics (PKs) Investigation of GSK3186899 in Healthy Subjects
Status: TERMINATED
Conditions: Leishmaniasis
Interventions: DRUG: GSK3186899|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Immunogenicity of a Single 40-ug Dose of rBV A/B for the Production of BabyBIG®
Status: ENROLLING_BY_INVITATION
Conditions: Botulism
Interventions: BIOLOGICAL: rBV A/B
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 68Ga-DOTA-F2 PET/CT in Patients With Various Types of Cancer
Status: RECRUITING
Conditions: Tumor, Solid
Interventions: DIAGNOSTIC_TEST: 68Ga-DOTA-F2 PET/CT and 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IOP Changes With Different Anesthetic Agents During Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Sintilimab|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Fluorouracil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Combined Neck Strength Exerciser Plus Physiotherapy to Treatment Chronic Neck Pain
Status: COMPLETED
Conditions: Cervicalgia
Interventions: OTHER: Physical therapy|DEVICE: Neck Strength Exerciser (NSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous And Oral Casopitant (GW679769) For The Prevention Of Chemotherapy Induced Nausea And Vomiting
Status: COMPLETED
Conditions: Vomiting|Nausea|Nausea and Vomiting, Chemotherapy-Induced
Interventions: DRUG: Casopitant (GW679769) oral tablets|DRUG: Casopitant (GW679769) intravenous|DRUG: Dexamethasone intravenous|DRUG: Ondansetron oral tablets|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of 0.15% Brimonidine Tartrate in Patients With Primary Open Angle Glaucoma and Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: 0.15% Brimonidine Tartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Visiting for Low Income, Pregnant Women
Status: COMPLETED
Conditions: Pregnant Women|Nutrition During Pregnancy|Breast Feeding|Newborns
Interventions: BEHAVIORAL: In-home Mentor Mother visits|BEHAVIORAL: Health Information Mailings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Digestive System Diseases|Colonic Diseases, Functional|Colitis, Mucous|Colon, Irritable
Interventions: DIETARY_SUPPLEMENT: Kyodophilus multi-strain probiotic capsules|DIETARY_SUPPLEMENT: Kyodophilus Matching Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: intensity modulated radiotherapy|PROCEDURE: DRE-Endoscopy-MRI-CEA|PROCEDURE: Nonoperative Management|PROCEDURE: Local Excision|PROCEDURE: Total Mesorectal Excision|BEHAVIORAL: Quality of Life Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Time to Accurate Heart Rate on Neonatal Outcomes
Status: COMPLETED
Conditions: Premature Infant|Extremely Low Birth Weight|Extreme Prematurity
Interventions: DEVICE: iRes Warmer with ResusView|OTHER: iRes Warmer without ResusView
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vision Preservation and Restoration Following a 6 Month Trial of GlaucoCetin
Status: UNKNOWN
Conditions: Primary Open Angle Glaucoma
Interventions: DIETARY_SUPPLEMENT: GlaucoCetin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Oral Etrasimod in Adult Participants With Moderate-to-Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Etrasimod|DRUG: Etrasimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Trial of the iAMHealthy Intervention
Status: COMPLETED
Conditions: Obesity; Rurality
Interventions: BEHAVIORAL: the iAmHealthy Behavioral Intervention|BEHAVIORAL: Newsletter only arm|OTHER: Consecutive Recruitment|OTHER: Traditional Recruitment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Far Infrared Irradiation for Managing and Treating Multiple Sclerosis (MS)
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: RADIATION: Far Infrared Radiation (5μm to 20μm wavelength)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Human Insulin Inhalation Powder|DRUG: Injectable Insulin|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Gastric Plication for Weight Loss in Morbidly Obese Patients Prior to Incisional Hernia Repair
Status: WITHDRAWN
Conditions: Morbid Obesity|Weight Loss|Complex Incisional Hernias
Interventions: PROCEDURE: Endoscopic Gastric Plication
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies
Status: RECRUITING
Conditions: Bone Marrow Transplant Complications|Graft Versus Host Disease|Infection Viral|Engraft Failure|Immunologic Suppression
Interventions: DRUG: Cyclophosphamide|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: To Study the Safety and Clinical Outcomes of the Absorb Bioresorbable Vascular Scaffold (BVS) System in Patients With de Novo Lesions in Previously Untreated Vessels
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: Absorb BVS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transvaginal Versus Transabdominal Extraction of Laparoscopically-excised Specimen
Status: COMPLETED
Conditions: Colorectal Neoplasms|Urologic Neoplasms|Gastrointestinal Neoplasms|Neoplasms by Site
Interventions: PROCEDURE: Transvaginal natural orifice specimen extraction (NOSE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MySkin Patch for the Healing of Cut Injuries and Abrasions
Status: COMPLETED
Conditions: Wounds and Injuries|Abrasion|Cut Injuries
Interventions: DEVICE: MySkin patch|DEVICE: Gauze and Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lucinactant for Treatment of Acute Hypoxemic Respiratory Failure in Children up to Two Years Old
Status: COMPLETED
Conditions: Acute Hypoxemic Respiratory Failure
Interventions: DRUG: Lucinactant|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Additional Physiotherapy for Patients Aged 75 and Older
Status: TERMINATED
Conditions: Exercise|Hospitalisation|Older Adults
Interventions: OTHER: Strengthening exercises|OTHER: Stretching exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised Controlled Trial Comparing Single Shot Adductor Canal Block With Local Infiltration Analgesia for Postoperative Analgesia After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Analgesia in Total Knee Arthroplasty
Interventions: PROCEDURE: Adductor Canal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Bendamustine Hydrochloride, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: DRUG: Bendamustine Hydrochloride|DRUG: Carfilzomib|DRUG: Dexamethasone|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sodium Bicarbonate in Cardiac Surgery Study
Status: TERMINATED
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: DRUG: Sodium Bicarbonate|DRUG: Sodium Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Strategies for Asymmetrical Triacetate Dialyzer Heparin-Free Effective Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis Complication
Interventions: DEVICE: dialyzer|COMBINATION_PRODUCT: hemodialysis with citrate-containing dialysate|OTHER: predilution hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Risperidone|DRUG: Aripiprazole|DRUG: Ziprasidone|DRUG: Amisulpride|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Practical Anemia Bundle for SusTained Blood Recovery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anemia|Critical Illness
Interventions: DRUG: Iron Dextran|DRUG: Erythropoietin (EPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arsenic Trioxide and Tyrosine Kinase Inhibitors for Chronic Myelogenous Leukemia (CML)
Status: TERMINATED
Conditions: Chronic Myelogenous Leukemia
Interventions: DRUG: Arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HGXJT in Bone Metastatic NSCLC Patients
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: ICI|DRUG: Chemotherapy|DRUG: Placebo|DRUG: Bone-protecting and Mass-dispersesing Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Glioblastoma Multiforme (Grade IV) of Cerebellum
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs
Status: RECRUITING
Conditions: HIV Infections|Opioid Use|Trauma, Psychological
Interventions: BEHAVIORAL: Expressive Writing|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Fecal Microbiota Transplantation and ACHIM for Manipulating Gut Microbiota in IBS Patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Dysbiosis
Interventions: DIETARY_SUPPLEMENT: Anaerobically Cultivated Human Intestinal Microbiota (ACHIM)|DIETARY_SUPPLEMENT: Donor fecal microbiota transplantation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Remimazolam Tosylate for Sedation in Gastroscopy
Status: RECRUITING
Conditions: Hypoxia|Gastric Cancer|Sedation Complication|Propofol Adverse Reaction
Interventions: DRUG: Remimazolam tosylate|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis
Status: RECRUITING
Conditions: Oral Cavity Cancer|Head and Neck Cancers - Tonsils|Esophageal Cancer|Laryngeal Cancer|Oropharynx Cancer|Mediastinal Cancer|Chest Wall Tumor|Radiation Mucositis
Interventions: DIETARY_SUPPLEMENT: 100% Aloe Vera Juice|COMBINATION_PRODUCT: Magic Mouthwash|COMBINATION_PRODUCT: Salt and Baking soda rinse|DRUG: Carafate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Efficacy of Enhancing Cognitive Reserve in Patients With a First Bipolar Episode
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: BEHAVIORAL: Enhancing cognitive reserve|OTHER: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Guiding Instillation in Non Muscle-invasive Bladder Cancer Based on Drug Screens in Patient Derived Organoids
Status: RECRUITING
Conditions: Bladder Cancer|Non-muscle Invasive
Interventions: DRUG: Epirubicin|DRUG: Mitomycin|DRUG: Gemcitabine|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Distant Reiki Application on Pain, Functional Status and Sleep Quality
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BEHAVIORAL: Distant reiki group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amlodipine/Atorvastatin Combination to Reduce the Health Risk of High Blood Pressure and High Cholesterol Levels
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Amlodipine/atorvastatin single pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pain and Anxiety in Children With Intramuscular Injection
Status: COMPLETED
Conditions: Intramuscular Myxoma
Interventions: BEHAVIORAL: Distraction Card|BEHAVIORAL: Stress Ball
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Outcomes of Straight-line Flow Versus Angiosome-targeted Angioplasty in Treatment of Critical Lower Limb Ischemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Angioplasty|Critical Lower Limb Ischemia
Interventions: PROCEDURE: peripheral angioplasty for tibial vessels
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Soil-transmitted Helminth Reinfection Rates After Single and Repeated School Hygiene Education
Status: UNKNOWN
Conditions: Helminthiasis|Ascaris Infection|Trichuris Infection|Hookworm Infections|Children, Only
Interventions: BEHAVIORAL: Health hygiene education
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Benefits of Eggs in Combination With a Plant-based Diet
Status: COMPLETED
Conditions: Coronary Artery Disease|Diabetes|Metabolic Syndrome
Interventions: OTHER: Consume 2 eggs with spinach per day|OTHER: Egg Subsitute with spinach per day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection
Status: COMPLETED
Conditions: Candidiasis|Candidemia
Interventions: DRUG: voriconazole (Vfend)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Conservative Management on Relieving Storage Urinary Symptoms and Poor Sleep in Women With Diabetes
Status: RECRUITING
Conditions: Conservative Management|Diabetes Mellitus|Health-related Quality of Life|Lower Urinary Tract Symptoms|Self-management|Sleep|Sleep Health
Interventions: BEHAVIORAL: Sleep health promotion|BEHAVIORAL: Urologic health promotion|BEHAVIORAL: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dye Taping Technique Versus Robert Debre Method On Foot Posture And Range Of Motion In Children With Club Foot.
Status: COMPLETED
Conditions: Club Foot
Interventions: OTHER: Low Dye Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A 24 Month Study to Compare Efficacy of Doxycycline vs Placebo for Improving Filarial Lymphedema in Sri Lanka
Status: COMPLETED
Conditions: Lymphedema|Lymphatic Filariasis|Filariasis
Interventions: DRUG: Doxycycline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine in Children and Adolescents (MK-0462-082 AM7)
Status: COMPLETED
Conditions: Migraine, Acute
Interventions: DRUG: rizatriptan|DRUG: placebo|DRUG: rizatriptan|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effects Of Repeat Dosing Of Esomeprazole On The Pharmacokinetics Of SB-751689 In Healthy People
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: SB-751689
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Flexibility Program on the Extensibility of the Hamstrings and the Thoracic and Lumbar Spinal Curvatures
Status: COMPLETED
Conditions: Spine Injury|Hamstring Injury|Lumbar Hyperlordosis|Kyphosis
Interventions: OTHER: Flexibility training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: IPACK Nerve Block for Total Knee Arthroplasty
Status: COMPLETED
Conditions: Arthropathy of Knee|Anesthesia
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Lipid Apheresis in Patients With Elevated Lipoprotein(a)
Status: WITHDRAWN
Conditions: Hyperlipoproteinemia(a)|Progressive Cardiovascular Disease
Interventions: PROCEDURE: Lipid apheresis|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Metionac for the Modulation of Metabolic and Endocrine Parameters in Patients With PCOS.
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Metionac|DRUG: Oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline Accelerates Intracerebral Hemorrhage Absorption
Status: NOT_YET_RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Minocycline|OTHER: starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Project CLEAR - Changing Lives by Eradicating Antibiotic Resistance
Status: COMPLETED
Conditions: Methicillin-resistant Staphylococcus Aureus
Interventions: BEHAVIORAL: Standard-of-Care Education|DRUG: MRSA Decolonization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Peroxide Level in Saliva During Teeth Bleaching With 9.5% Hydrogen Peroxide Gel
Status: COMPLETED
Conditions: Consumption|Toxicity
Interventions: OTHER: 9.5% hydrogen peroxide bleaching (POLA DAY advanced tooth whitening system, SDI) using a tray with reservoir|OTHER: 9.5% hydrogen peroxide bleaching (POLA DAY advanced tooth whitening system, SDI) using a tray without reservoir.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder|Suicide
Interventions: DRUG: Fluoxetine|BEHAVIORAL: DBT|DRUG: Citalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: BIOLOGICAL: ZFN modified T cells|OTHER: Structured Treatment Interruption
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Invasive and Clinical Features in Patients With Brugada Syndrome Undergoing Catheter Ablation
Status: RECRUITING
Conditions: Brugada Syndrome
Interventions: DEVICE: Radiofrequency catheter ablation|DEVICE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT