pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Remote Alcohol Monitoring and Episodic Thinking
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol-Related Disorders
Interventions: BEHAVIORAL: Episodic Future Thinking (EFT)|BEHAVIORAL: Episodic Recent Thinking (ERT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Triage - Symptoms and Other Predictors in an All-comer Emergency Department Population; (EKBB 236/13)
Status: COMPLETED
Conditions: Triage Risk Stratification
Interventions: OTHER: Assessment of symptoms patients presenting when admitted to ED|OTHER: Reason for patient presentation at ED|OTHER: physicians rating of severity of illness|DIAGNOSTIC_TEST: Assessment of vital signs|OTHER: Clinical Frailty Scale|OTHER: Impaired mobility on presentation (IMOP)|OTHER: Assessment of suspected diagnosis and differential diagnoses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intrathecal Morphine and Local Infiltration Analgesia in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Bupivacaine Hydrochloride, Spinal|DRUG: Morphine hydrochloride, Spinal|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on the Metabolic Control and Body Composition of Type 2 Diabetes Subjects in Ajman (UAE)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity|Hypovitaminosis D
Interventions: DIETARY_SUPPLEMENT: Vitamin D3(cholecalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factor In the Initial Resuscitation of Severe Trauma 2 Patients
Status: RECRUITING
Conditions: Traumatic Hemorrhage|Coagulopathy|Massive Hemorrhage
Interventions: BIOLOGICAL: Fibrinogen + PCC|BIOLOGICAL: Frozen Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Verapamil SR in Adults With Type 1 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Verapamil SR 120 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: SDF for the Management of Dental Caries in Children in Primary Dental Care: Protocol for a Feasibility Study
Status: RECRUITING
Conditions: Dental Caries in Children
Interventions: DEVICE: Silver diamine fluoride|PROCEDURE: Usual dental care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery
Status: TERMINATED
Conditions: Colorectal Cancer|Diverticular Disease|Crohn Disease|Ulcerative Colitis
Interventions: GENETIC: PGx-guided post-operative pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 5HT2CR Balance in Brain Connectivity in Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Mirtazapine 15 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preoperative Micronized Flavonoid Fraction (MFF) Use in Multimodal Anesthesia in Anorectal Surgery
Status: COMPLETED
Conditions: Hemorrhoids|Hemorrhoid Pain|Hemorrhoidal Bleeding
Interventions: DRUG: micronized flavonoid fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Couple-based Intervention on Quality of Life in HIV Male Serodiscordant Couples
Status: RECRUITING
Conditions: Quality of Life|Hiv|Relationship, Social
Interventions: BEHAVIORAL: Couple-based Dyadic Coping Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Aflibercept as Adjunctive Treatment for Filtration Surgery in Neovascular Glaucoma
Status: COMPLETED
Conditions: Intraocular Pressure|Neovascular Glaucoma|Vascular Endothelial Growth Factor Overexpression|Glaucoma Secondary to Eye Inflammation
Interventions: DRUG: Aflibercept Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HoLEP vs BPRP in the Management of a Large Volume (> 80 gm) Symptomatic BPH
Status: COMPLETED
Conditions: BPH With Urinary Obstruction|Male
Interventions: PROCEDURE: holmium laser enucleation of the prostate|PROCEDURE: Bipolar resection of the prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension
Status: COMPLETED
Conditions: Portopulmonary Hypertension|Pulmonary Arterial Hypertension|Pulmonary Hypertension
Interventions: DRUG: Treprostinil
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of LEO 19123 Cream in the Treatment of Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 19123 Cream (calcipotriol plus LEO 80122)|DRUG: Dovonex® cream|DRUG: Cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Tolerability, Safety and Effectiveness of Edratide in the Treatment of Lupus
Status: TERMINATED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: edratide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Safety, Tolerability, PK Study of IV CXA-10 Emulsion in Subjects in Chronic Kidney Injury
Status: COMPLETED
Conditions: Acute Kidney Injury (Nontraumatic)
Interventions: DRUG: CXA-10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Shotblocker, Finger Puppet And Balloon Method During Intramuscular Injection
Status: COMPLETED
Conditions: Children
Interventions: DEVICE: ShotBlocker|OTHER: Finger Puppet group|OTHER: Balloon group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of New Protocols in the Treatment of Upper Limb Dysfunctions in Patients With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: Low dosage SES group|DEVICE: High dosage SES group|DEVICE: VRCIT group|DEVICE: VRCIT+SES group|PROCEDURE: traditional rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship of DASH and Mediterranean Diet Score With Serum Adiponectin Levels in Patients With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: OTHER: Keeping a 1-day food consumption record by the patient|OTHER: Measurement of adiponectin level
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Versus High-glycemic Index Post-exercise Diets for Improving Metabolism and Body Composition
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Low glycemic index post-exercise diet|DIETARY_SUPPLEMENT: High glycemic index post-exercise diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Combined treatment with Arimidex and Zoladex before IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Metoclopramide in the Acute Treatment of Migraine: A Double-blind, Randomized, Placebo-controlled Trial
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Metoclopramide 10 mg|DRUG: Placebo|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Imaging of Vulnerable Plaques in Coronary Artery Disease by Multidetector Computed Tomography
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: RADIATION: Multidetector computed tomography scanning|PROCEDURE: Coronary angiography (CAG)|PROCEDURE: Intravascular ultrasound|PROCEDURE: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Eliminate Hepatitis C/EC Partnership Evaluation Protocol
Status: UNKNOWN
Conditions: Hepatitis C|Chronic Hepatitis c|Hepatitis C, Chronic
Interventions: OTHER: EC clinic support - whole of practice interventions delivery through nurse-led model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Correlation Between Dorsalis Pedis and Radial Arterial Invasive Blood Pressures During Anesthesia Induction in Neurosurgical Patients
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DIAGNOSTIC_TEST: invasive blood pressure monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Tolerability of Maintenance Treatment With Asmanex Twisthaler Versus Placebo in Mild/Moderate Persistent Asthmatics (Study P04654)(TERMINATED)
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Asmanex twisthaler|OTHER: Placebo for Asmanex twisthaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPICC-HPV)
Status: WITHDRAWN
Conditions: Vaccine Decision Making
Interventions: OTHER: Vacteens Web app for mobile devices|OTHER: Standard Usual and Customary HPV Information - CDC pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Retrospective Evaluation of Athens Complete Health Improvement Program (CHIP) Database
Status: COMPLETED
Conditions: Cardiovascular Diseases|Diabetes Mellitus|Hypertension|Dyslipidemias|Overweight and Obesity
Interventions: BEHAVIORAL: The Complete Health Improvement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AZD6094 (Volitinib) in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Third-line Treatment
Status: COMPLETED
Conditions: Advanced Gastric Adenocarcinoma
Interventions: DRUG: Volitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Plus Rituximab Versus Fludarabine Plus Rituximab
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Bendamustine plus Rituximab|DRUG: Fludarabine 25 mg/m² d 1-3 + Rituximab 375 mg/m² d 1 q4w
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing General Anesthesia With Single Injection Peribulbar Block With 3 Different Drugs
Status: RECRUITING
Conditions: Pediatric Squint Surgeries
Interventions: DRUG: Articaine and Epinephrine Only Product|DRUG: levobupivacaine|DRUG: mepivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: An Attempt at Translating Novelty-enhanced Extinction of Context Conditioning From Rodents to Humans
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Novel Exploration|BEHAVIORAL: Threat conditioning|BEHAVIORAL: Extinction|BEHAVIORAL: Reinstatement|BEHAVIORAL: Visual attention control task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liposomal Amphotericin B (Ambisome) Versus Oral Voriconazole for the Prevention of Invasive Fungal Infections
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Voriconazole|DRUG: Liposomal amphotericin B|DRUG: Liposomal amphotericin B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Randomised Controlled Trial to Evaluate the Impact of Complement Theory's Live 1:1 Exercise Coaching and Personalised Digital Application on Cancer Survivors' Cost of Care
Status: RECRUITING
Conditions: Breast Cancer|Lung Cancer|Prostate Cancer|Colorectal Cancer|Other Cancer
Interventions: BEHAVIORAL: Complement Theory's Live 1:1 Exercise Coaching and Personalized Digital Application|BEHAVIORAL: Digital application with expert guidelines on lifestyle modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vaginal Estrogen and Pelvic Floor Physical Therapy in Women With Symptomatic Mild Prolapse
Status: RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: DRUG: Vaginal estrogen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myeloproliferative Disorders|Anemia, Refractory, With Excess of Blasts
Interventions: DRUG: Hum-195/rGel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Gag Reflex in Healthy Persons and Across Different Patient Groups and Its Relevance in Dysphagia Screening
Status: RECRUITING
Conditions: Neurological Diseases or Conditions
Interventions: DIAGNOSTIC_TEST: Gag reflex test; assessment of Mallampati Score
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Dupilumab Auto-injector Device When Used by Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Disorders|Eczema, Atopic
Interventions: DRUG: Dupilumab|DEVICE: Auto-injector Device|DEVICE: Prefilled syringe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lamotrigine Tablets 25 mg|DRUG: Lamictal® Tablets 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: motesanib diphosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Detection Method for Microorganisms in the Lower Genital Tract
Status: NOT_YET_RECRUITING
Conditions: Infertility, Female
Interventions: DIAGNOSTIC_TEST: lower genital tract microorganisms detection using Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biomechanical Assessment of a High Congruency Knee Bearing
Status: UNKNOWN
Conditions: Knee Replacement
Interventions: DEVICE: Mobile high congruency bearing (Columbus)|DEVICE: Fixed high congruency bearing (Columbus)|DEVICE: Fixed high congruency bearing (Columbus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vertebral Osteosynthesis in Degenerative Lumbar Stenosis With Spondylolisthesis
Status: TERMINATED
Conditions: Spondylolisthesis
Interventions: PROCEDURE: Osteosynthesis|PROCEDURE: Simple surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BATTLE Trial: Bare Metal Stent Versus Paclitaxel Eluting Stent in the Setting of Primary Stenting of Intermediate Length Femoropopliteal Lesions
Status: TERMINATED
Conditions: Peripheral Arterial Disease|Femoropopliteal Lesions
Interventions: DEVICE: Misago RX|DEVICE: Zilver PTX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Native Coronary Artery Instead of SAphenous Vein Graft Intervention for Treatment of Significant Saphenous Vein Graft Lesions
Status: RECRUITING
Conditions: Target Vessel Failure in Saphenous Vein Grafts|Percutaneous Coronary Intervention
Interventions: PROCEDURE: Percutaneous coronary intervention of the native coronary artery with Synergy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients
Status: RECRUITING
Conditions: Antimicrobial Drug Resistance|Antibiotic Resistant Infection|Clostridium Difficile|Carbapenem-Resistant Enterobacteriaceae Infection|Extended Spectrum Beta-Lactamase Producing Bacteria Infection|Vancomycin Resistant Enterococci Infection|Carbapenem Resistant Bacterial Infection|Vancomycin-Resistant Enterococcal Infection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Creatine and GAA for Brain Oxygenation
Status: COMPLETED
Conditions: Oxygen Deficiency
Interventions: DIETARY_SUPPLEMENT: Supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pain Outcomes After Anterior Cruciate Ligament Reconstruction With Posterior Capsular Marcaine Injection
Status: TERMINATED
Conditions: Anesthesia
Interventions: DRUG: Marcaine|OTHER: Ice|DRUG: Percocet|DEVICE: Knee Brace and Crutches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase III Double-blind Comparative Study of BAY77-1931 (Lanthanum Carbonate) With Calcium Carbonate
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Lanthanum carbonate (BAY77-1931)|DRUG: Calcium carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parmigiano-Reggiano Cheese as a Possible Strategy to Acquire Oral Tolerance in Children With Cow's Milk Allergy
Status: UNKNOWN
Conditions: Cow's Milk Allergy
Interventions: DIETARY_SUPPLEMENT: Parmigiano Reggiano cheese
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
Status: COMPLETED
Conditions: Interaction|Endogenous Biomarkers
Interventions: DRUG: MetFORMIN Oral Solution|DRUG: Cimetidine 400 MG|DRUG: Furosemide Oral Liquid Product|DRUG: Probenecid 500 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Extracellular Vesicles (EV) in Patients Undergoing CAR-T Cell Therapies
Status: NOT_YET_RECRUITING
Conditions: CAR-T Cell Therapy|Extracellular Vesicles
Interventions: OTHER: Patients who are candidates for CAR-T cell therapy for hematologic malignancy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BETTY: BEnign Prostatic Hyperplasia Transperineal Targeted Microwave therapY
Status: RECRUITING
Conditions: Prostate Hyperplasia
Interventions: DEVICE: 3D-Ultrasound-Guided Transperineal Microwave needle ablation of BPH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ramucirumab/Paclitaxel as Second-line Treatment in Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma With Integrative Genomic Analysis
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: DRUG: Ramucirumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms
Status: RECRUITING
Conditions: Urinary Incontinence|Overactive Bladder Syndrome|Overactive Bladder|Urologic Diseases
Interventions: DRUG: OnabotulinumtoxinA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Automatic Oxygen Titration System in People With Hypoxemia During Exercise Training
Status: RECRUITING
Conditions: Hypoxaemia|Chronic Lung Disease
Interventions: OTHER: Oxygen therapy - constant oxygen flow|OTHER: Oxygen therapy - automatic titrating oxygen flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients
Status: UNKNOWN
Conditions: Septic Shock
Interventions: PROCEDURE: Fluid resuscitation and furosemide administration (bolus and continuous) with central venous pressure target 8 - 10 mmHg|PROCEDURE: Fluid deresuscitation and furosemide administration (bolus and continuous) with central venous pressure target 0 - 4 mmHg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Equine-assisted Therapy for Therapy-resistant Adolescents With Autism Spectrum Disorders, a Replicated AB-design
Status: RECRUITING
Conditions: Emotion Regulation|Autism Spectrum Disorder|Adolescent - Emotional Problem
Interventions: BEHAVIORAL: Equine assisted Therapy (EAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relugolix in Combination With Radiation Therapy for Treating Patients With High Risk Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Stage IIC Prostate Cancer AJCC v8|Stage III Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|RADIATION: Brachytherapy|PROCEDURE: Computed Tomography|PROCEDURE: Dual X-ray Absorptiometry|RADIATION: External Beam Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: PSMA PET Scan|OTHER: Questionnaire Administration|DRUG: Relugolix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Satisfaction in Adult Participants With the Aesthetics of the Periorbital Area After JUVÉDERM® Fillers and BOTOX®/VISTABEL® Injections
Status: COMPLETED
Conditions: Facial Corrections|Facial Lines
Interventions: DRUG: BOTOX®/VISTABEL®|DEVICE: Juvéderm® VOLBELLA® with Lidocaine|DEVICE: Juvéderm® VOLIFT® with Lidocaine|DEVICE: Juvéderm® VOLUMA® with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Sandoz Inc. and UCB Pharma, Inc (Keppra) 750 mg Levetiracetam Tablets In Healthy Adults Volunteers Under Fasting Conditions
Status: COMPLETED
Conditions: Seizure
Interventions: DRUG: Levetiracetam Tablets, 750 mg (Sandoz Inc.)|DRUG: Keppra (Levetiracetam) Tablets, 750 mg (UCB Pharma, Inc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Versus Multi-Dose Oral Tranexamic Acid in Patients at High Risk for Blood Transfusion After Total Joint Arthroplasty
Status: WITHDRAWN
Conditions: Anemia|Arthritis|Total Knee Arthroplasty|Total Hip Arthroplasty
Interventions: DRUG: Conventional Oral TXA (Tranexamic Acid)|DRUG: Multi-Dose Oral TXA (Tranexamic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Introducing an Onsite Test for Syphilis in the Package of Antenatal Care in Burkina Faso
Status: COMPLETED
Conditions: Syphilis Infection|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: Feasibility of introducing onsite test for syphilis in the package of antenatal care at rural primary health care in Burkina Faso
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photobiomodulation Therapy in Patients Receiving Total Knee Arthroplasty
Status: RECRUITING
Conditions: Inflammation|Osteoarthritis|Post Operative Pain
Interventions: DEVICE: Photobiomodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Biomarkers Related to Periodontal Disease Activity in Diabetic
Status: COMPLETED
Conditions: Periodontitis|Type 2 Diabetes Mellitus
Interventions: DRUG: non-surgical periodontal therapy + systemic doxycycline|PROCEDURE: Non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: ARTerial EMbolization for haemorrhoIdal Disease (ART.EM.I. Study)
Status: WITHDRAWN
Conditions: Haemorrhoidal Bleeding
Interventions: PROCEDURE: Coil embolisation of hemorrhoidal arteries.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab as First-line Monotherapy for Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Fentanyl for Management of Pain Associated With Cystoscopic Procedures
Status: COMPLETED
Conditions: Other Acute Pain|Pain Experienced During Cystoscopy
Interventions: DRUG: Fentanyl pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immediate Implant Placement With Immediate Loading With and Without Connective Tissue Graft
Status: UNKNOWN
Conditions: Pateint With Badely Decayed Anterior Teeth
Interventions: PROCEDURE: sub epithelial connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: An Investigational Drug, PF-02341066, Is Being Studied In Patients With Advanced Non-Small Cell Lung Cancer With A Specific Gene Profile Involving The Anaplastic Lymphoma Kinase (ALK) Gene
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: PF-02341066
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
Status: NOT_YET_RECRUITING
Conditions: Post-Traumatic Stress Disorder (PTSD)
Interventions: DRUG: Oxytocin nasal spray|DRUG: Saline nasal spray|BEHAVIORAL: Brief Cognitive-Behavioral Conjoint Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CTC Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Adenocarcinoma|Circulating Tumor Cells|Pancreatic Neoplasms
Interventions: DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Sildenafil Administration for Hepatectomy
Status: RECRUITING
Conditions: Central Venous Pressure|Hepatectomy|Hemodynamics Instability|Sildenafil
Interventions: DRUG: Sildenafil 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Rituximab Induction Therapy Followed by Glatiramer Acetate
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Rituximab|DRUG: Glatiramer Acetate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Two Medications as First Treatment in Elderly Patients With Metastatic or Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: Pazopanib|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: rosiglitazone/metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: Ipilimumab|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Trial in Overweight and Obese Patients, Investigating Effect of EMP16-02 on Body Weight (Primary)
Status: COMPLETED
Conditions: Overweight or Obesity
Interventions: DRUG: EMP16-02 120 mg orlistat/40 mg acarbose|DRUG: EMP16-02 150 mg orlistat/50 mg acarbose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C2 CryoBalloon™ 180 Ablation System Dose De-escalation Study.
Status: ENROLLING_BY_INVITATION
Conditions: Barrett Esophagus
Interventions: DEVICE: C2 CryoBalloon 180° Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Guided Transversus Abdominis Plane Block Versus Trocar Site Infiltration in Gynecologic Laparoscopy.
Status: COMPLETED
Conditions: Post Operative Local Anaesthesia
Interventions: DRUG: Laparoscopic Guided Bupivacaine|DRUG: local Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P300 Brain Computer Interface Keyboard to Operate Assistive Technology
Status: COMPLETED
Conditions: Healthy|Amyotrophic Lateral Sclerosis|Neuromuscular Disease|Spinal Cord Injury|Cerebral Palsy
Interventions: DEVICE: Brain Computer Interface Keyboard
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Submucosal Dissection Versus Transanal Endoscopic Microsurgery For Early Rectal Neoplasms And Large Rectal Adenomas: Сomparison Of Treatment Efficacy And Safety.
Status: UNKNOWN
Conditions: Early Rectal Cancer|Large Rectal Adenomas
Interventions: PROCEDURE: transanal endoscopic microsurgery|PROCEDURE: endoscopic submucosal dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Anterior Approach|PROCEDURE: Posterior Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transdisciplinary Versus Usual Care for Type1 Diabetes in Adolescence
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: OTHER: Usual Care|BEHAVIORAL: Transdisciplinary Care-In Person & Telehealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Hematopoietic Stem Cell Transplantation for Early Onset Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: AHSCT|DRUG: Insulin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the SENSEI® Laparoscopic Tethered Gamma Probe for 99mTc-nanocolloid Sentinel Lymph Node Biopsy in Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DEVICE: SENSEI®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations
Status: NOT_YET_RECRUITING
Conditions: OTOF Gene Mutation|DFNB9|Congenital Deafness|Hearing Disorders|Ear Diseases|Otorhinolaryngologic Diseases|Deafness|Hearing Loss, Sensorineural
Interventions: COMBINATION_PRODUCT: SENS-501 administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Multimodal Preference-based Parental Intervention on Preschoolers' Physical Activity Behaviour - a Cluster-randomized Trial
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Participatory parent-focused intervention|BEHAVIORAL: State-sponsored PA program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ABI-aftercare in Motion: Multidisciplinary Aftercare in the Home Environment in Patients With Acquired Brain Injury
Status: RECRUITING
Conditions: Acquired Brain Injury
Interventions: BEHAVIORAL: ABI-motion program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Extension Trial Assessing the Safety and Efficacy of BI 655066/ABBV-066/Risankizumab in Patients With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Risankizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)
Status: RECRUITING
Conditions: Primary Progressive Multiple Sclerosis
Interventions: DRUG: Tolebrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Propolis Mouthwash Compared to Chlorhexidine Mouthwash on Oral and Cardiovascular Health
Status: COMPLETED
Conditions: Blood Pressure|Periodontal Diseases
Interventions: OTHER: Propolis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)
Status: TERMINATED
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: Sliding Hip Screw|PROCEDURE: Cancellous Screws|DRUG: Vitamin D|DRUG: Vitamin D Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-Serine for Cocaine Dependence Pilot
Status: WITHDRAWN
Conditions: Cocaine Dependence
Interventions: DRUG: D-serine|BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation
Status: UNKNOWN
Conditions: Functional Constipation
Interventions: OTHER: dietary intervention with oligosaccharides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DSP-0390 in Patients With Recurrent High-Grade Glioma
Status: ACTIVE_NOT_RECRUITING
Conditions: High Grade Glioma|Glioblastoma Multiforme
Interventions: DRUG: DSP-0390
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder (PALISADE-3)
Status: RECRUITING
Conditions: Social Anxiety Disorder
Interventions: DRUG: Fasedienol Nasal Spray|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Association of Affective Resonance With Empathy Modulated by Negative Symptomatology and Oxytocin
Status: COMPLETED
Conditions: Schizophrenia Spectrum Disorders
Interventions: OTHER: Oxytocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Resveratrol to Decrease Acute Secondary Brain Injury Following Sports-Related Concussions in Boxers
Status: COMPLETED
Conditions: Sports Concussion
Interventions: DRUG: Resveratrol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ofatumumab as Part of Reduced Intensity Conditioning (RIC) Regimen for Patients With High Risk Chronic Lymphocytic Leukemia (CLL) Undergoing Allogeneic Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Ofatumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Could Pre-operative Rectal Misoprostol Reduce Intra-operative Blood Loss During Ceserean Section?
Status: COMPLETED
Conditions: Postpartum Haemorrhage
Interventions: DRUG: misoprostol|DRUG: placeboo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PET Scan Combined With CT Scan in Evaluating Treatment Response in Patients Undergoing Treatment for Bone Cancer or Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: PROCEDURE: positron emission tomography computed tomography (PET/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of HSK21542 in Inducing Postoperative Analgesia in Undergoing Elective Laparoscopic Surgery
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Experimental: stage I：HSK21542 0.4 μg/kg|DRUG: Experimental: stage I：HSK21542 1 μg/kg|DRUG: Experimental: stage I：HSK21542 0.5μg/kg|DRUG: Experimental: stage I：HSK21542 1μg/kg|DRUG: Experimental: stage II：HSK21542 0.5μg/kg|DRUG: Experimental: stage II：HSK21542 1μg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Very Low Carbohydrate Diet Intervention on Weight Control in Overweight/Obese Patients in China
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: diet nutrition bar|OTHER: energy-restricted diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Augmented Renal Clearance in the Adult Non-critically Ill Surgery Patient: a Prospective Point Prevalance Study
Status: COMPLETED
Conditions: Prevalence of Augmented Renal Clearance|Risk Factors for Augmented Renal Clearance
Interventions: OTHER: Augmented renal clearance Point prevalence study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks
Status: COMPLETED
Conditions: Orthopedic Disorder
Interventions: DRUG: Ropivacaine Hcl 0.5% Inj Vil 20Ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Granulocyte Colony Stimulating Factor (G-CSF) in Acute Liver Failure and Alcoholic Hepatitis
Status: UNKNOWN
Conditions: Liver Failure, Acute
Interventions: DRUG: Granulocyte colony stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-ascending Dose Study of Kylo-11 in Healthy Subjects
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DRUG: Kylo-11|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Alphagan and Xalatan Eye Drops on Corneal Temperature
Status: COMPLETED
Conditions: Primary Vascular Dysregulation
Interventions: DRUG: Brimonidine|DRUG: Latanoprost|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults
Status: TERMINATED
Conditions: Healthy Controls
Interventions: BIOLOGICAL: Clinical Center Reference Endotoxin (CCRE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exercise Therapy With Risk Factor Management and Life Style Coaching After Vascular Intervention for Patients With Peripheral Arterial Disease
Status: TERMINATED
Conditions: Peripheral Arterial Disease, Rutherford 4 and 5 With Possibility to Improve Vascularization
Interventions: BEHAVIORAL: Supervised Exercise Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intralesional Tranexamic Acid and Platelets Rich Plasma in the Treatment of Melasma
Status: COMPLETED
Conditions: Melasma
Interventions: DRUG: Tranexamic acid|DRUG: Platelets rich plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Multicenter Topic Trial
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Ivacaftor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resuscitation Table Height for Face-mask Ventilation in Infants
Status: COMPLETED
Conditions: Asphyxia|Resuscitation|Newborn Morbidity
Interventions: OTHER: High resuscitation table|OTHER: Low resuscitation table
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Liothyronine in MS
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive|Multiple Sclerosis, Primary Progressive
Interventions: DRUG: liothyronine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT