pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Lanreotide Autogel in Tumour Stabilization of Patients With Progressive Neuroendocrine Tumours
Status: COMPLETED
Conditions: Neuroendocrine Tumours
Interventions: DRUG: lanreotide (Autogel formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dronabinol as an Adjunct for Reducing Pain
Status: RECRUITING
Conditions: Low Back Pain|Chronic Pain|Back Injuries
Interventions: DRUG: Dronabinol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemoembolization With or Without Antiviral Therapy for Unresectable HBV-related HCC With Low HBV DNA Replication
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lamivudine 100mg once daily; or Entecavir 0.5mg once daily.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DLBS2411 Treatment for Ulcer Healing in Non-Bleeding Peptic Ulcers
Status: TERMINATED
Conditions: Non-Bleeding Peptic Ulcers
Interventions: DRUG: Omeprazole|DRUG: Placebo caplet of DLBS2411|DRUG: DLBS2411|DRUG: Placebo capsule of Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Transcranial Magnetic Stimulation and Cognitive Treatment in Blast Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Cognitive Dysfunction|Blast Injury
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation (rTMS)|BEHAVIORAL: Cognitive Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Food Study of Clopidogrel Bisulfate Tablets 75 mg to Plavix® Tablets 75 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clopidogrel Bisulfate Tablets 75 mg|DRUG: Plavix® Tablets 75 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Natural Sounds on Attention Restoration in Virtual Reality
Status: RECRUITING
Conditions: Cognitive Fatigue|Mental Fatigue|Behavioral Performance|Heart Rate Variability|Working Memory
Interventions: OTHER: Masking Sound|OTHER: No masking sound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior
Status: COMPLETED
Conditions: Lactose Intolerance
Interventions: DIETARY_SUPPLEMENT: Oral consumption milk Tetra Pak
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Internet-based Intervention to Promote a Healthy Lifestyle on the Reproductive Parameters of Overweight and Obese Women
Status: RECRUITING
Conditions: Obesity|Infertility, Female
Interventions: OTHER: Healthy Lifestyle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy
Status: TERMINATED
Conditions: Polypoidal Choroidal Vasculopathy
Interventions: DRUG: Lucentis® (Raibizumab) double-dose|DRUG: Lucentis® (Raibizumab) regular-dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK257049 Dosage 1|BIOLOGICAL: GSK257049 Dosage 2|PROCEDURE: Sporozoite-infected mosquitoes challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VITATOPS: A Study of VITAmins TO Prevent Stroke
Status: COMPLETED
Conditions: Stroke|Transient Ischemic Attack
Interventions: DRUG: Active VITATOPS Tablet (folic acid 2mg, B6 25mg , B12 500ug) or placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acetabular Cerclage and Total Hip Arthroplasty in the Treatment of Acetabular Fractures in Elderly Patients.
Status: WITHDRAWN
Conditions: Elderly|Acetabular Fractures|Cerclage Acetabular Fractures|Total Hip Arthroplasty
Interventions: DEVICE: Cerclage and total hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate the Efficacy and Safety of My-Rept® Tablet vs. My-Rept® Capsule in Combination With Tacrolimus in Kidney Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Mycophenolate Mofetil 500mg|DRUG: Mycophenolate Mofetil 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Delirium|Critical Illness|Intensive Care Unit Delirium|Thoracic Diseases|Respiratory Failure|Cardiac Disease|Cardiac Failure
Interventions: OTHER: COVID visitation restrictions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exenatide Once Weekly Over 2 Years as a Potential Disease Modifying Treatment for Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: Exenatide extended release 2mg (Bydureon)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: App-delivered Sleep ThERapy for Older Individuals With Insomnia
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: SleepFix mobile application|BEHAVIORAL: Sleep Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Out-of-hospital Cardiopulmonary Resuscitation and AED Feedback
Status: COMPLETED
Conditions: Cardiac Arrest|Resuscitation
Interventions: DEVICE: Zoll AED pro|DEVICE: Zoll AED pro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aronia and Non-alcoholic Fatty Liver Disease
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: OTHER: Aronia juice|OTHER: Mediterranean diet|OTHER: Low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on the Effects of Sacubitril/Valsartan on Physical Activity and Sleep in Heart Failure With Reduced Ejection Fraction Patients.
Status: COMPLETED
Conditions: Heart Failure, Reduced Ejection Fraction
Interventions: DRUG: sacubitril/valsartan (LCZ696)|DRUG: enalapril|DRUG: matching placebo sacubitril/valsartan (LCZ696)|DRUG: matching placebo enalapril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Dose-escalation Study of the Safety and Pharmacology of DAN-222 in Subjects With Metastatic Breast Cancer
Status: COMPLETED
Conditions: HER2-negative Metastatic Breast Cancer
Interventions: DRUG: DAN-222|DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Psychoeducational Intervention for Brain Awareness, Metacognition, Self-efficacy and Treatment Motivation
Status: COMPLETED
Conditions: Substance Use Disorders|Alcohol Use Disorder
Interventions: BEHAVIORAL: Brain Awareness Intervention|BEHAVIORAL: Being Healthy Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Normal Values for Esophageal and Pyloric Impedance Planimetry Under General Anesthesia (NormaFLIP)
Status: UNKNOWN
Conditions: Esophageal Dysfunction|Pylorus Dysfunction
Interventions: DEVICE: EndoFLIP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Sanofi Pasteur's Intradermal Influenza Vaccine (IDflu™) in Adults and Elderly in Korea
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: IDflu™: Split virion inactivated influenza vaccine|BIOLOGICAL: Vaxigrip®: Split virion inactivated influenza vaccine|BIOLOGICAL: IDflu™: Split virion inactivated influenza vaccine|BIOLOGICAL: Vaxigrip®: Split virion inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment
Status: COMPLETED
Conditions: Human Gastrointestinal Physiology Data
Interventions: DRUG: Single dose of ibuprofen (800 mg tablet)|DIETARY_SUPPLEMENT: Pulmocare, two 8.0 oz (236.6 mL) cans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.
Status: UNKNOWN
Conditions: Breast Neoplasm|Antineoplastic Agents|Antiemetics|Quality of Life
Interventions: DRUG: Palonosetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triple Therapy in Type 2 Diabetic Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Metformin|DRUG: Pioglitazone|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Regadenoson Versus Intravenous Adenoscan® for Fractional Flow Reserve (FFR)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: FFR Measurement with IV Adenoscan® then with Regadenoson
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparison of DFD01 Spray Versus Vehicle Spray in Subjects With Moderate Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: DFD01 Spray|DRUG: Vehicle Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Homeopathy for Post-operative (C. Section) Recovery
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: Bellis perennis and Staphysagria (C6)|DRUG: Bellis perennis and Staphysagria (C30)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasms|Laparotomy|Laparoscopy|Survival|Mortality|Recurrence
Interventions: PROCEDURE: Laparotomic radical hysterectomy|PROCEDURE: Laparoscopic radical hysterectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal Carcinoma
Interventions: DRUG: 5-Fluorouracil (5-FU)|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Atezolizumab|DRUG: Cobimetinib|BIOLOGICAL: Ramucirumab|DRUG: Paclitaxel|BIOLOGICAL: PEGylated recombinant human hyaluronidase (PEGPH20)|DRUG: BL-8040|DRUG: Linagliptin|DRUG: Atezolizumab|DRUG: Cobimetinib|DRUG: Cisplatin|DRUG: Tiragolumab|DRUG: 5-Fluorouracil (5-FU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Pharmacokinetics Study of TLC590 for Postsurgical Pain Management in Multiple Surgical Models
Status: NOT_YET_RECRUITING
Conditions: Postsurgical Pain Management
Interventions: DRUG: TLC590|DRUG: TLC590|DRUG: TLC590|DRUG: TLC590|DRUG: TLC590|DRUG: Ropivacaine|DRUG: TLC590
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Determine Absorption, Distribution, Metabolism, and Elimination of a Single Radiolabeled Dose of Brivanib (BMS-582664)
Status: COMPLETED
Conditions: Tumors
Interventions: DRUG: Brivanib|DRUG: Brivanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Potential for Adrenal Suppression Following Treatment With DSXS in Patients With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: DSXS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Interaction Study of an OCP (Norethindrone (ND) Acetate and Ethinyl Estradiol (EE))With a Combination of Daclatasvir (DCV) Asunaprevir (ASV) and BMS-791325
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: FDC of Daclatasvir, Asunaprevir and BMS-791325|DRUG: FDC of Norethindrone and Ethinyl Estradiol|DRUG: BMS-791325
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Headache and Patients' Satisfaction With the Treatment in Routine Clinical Practice
Status: COMPLETED
Conditions: Headache Disorders, Primary|Migraine With Aura|Migraine Without Aura|Tension-Type Headache
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biodistribution/Reproducibility Ga-68 PSMA-HBED-CC
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: (68Ga)PSMA-HBED-CC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravenous Lidocaine on Chronic Pain in Patients Undergoing Hepatectomy
Status: RECRUITING
Conditions: Postoperative Chronic Pain
Interventions: DRUG: Lidocaine Hydrochloride, Injectable|DRUG: 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET Study of the Nicotinic System in Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: RADIATION: MRI of the brain|RADIATION: PET scan [18F]F-A-85380|RADIATION: PET scan [18F]FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stress Management and Resiliency Training Program for Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Stress Management and Resiliency Training Program for Parkinson's Disease (SMART-PD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ramucirumab, Atezolizumab and N-803 After Progression on Any Immune Checkpoint Blocker in NSCLC
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer|Non-small Cell Carcinoma|NSCLC|Non Small Cell Lung Cancer
Interventions: DRUG: Ramucirumab|DRUG: Atezolizumab|DRUG: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
Status: TERMINATED
Conditions: Neurogenic Overactive Bladder|Urinary Incontinence|Detrusor Overactivity
Interventions: DEVICE: InterStim Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Montelukast Sodium 10mg Tablet Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Torrent's Montelukast Sodium Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: FOLFIRI + Cetuximab + Avelumab RAS Wild-type CRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment Related Cancer
Interventions: DRUG: 5-FU|DRUG: Folinic Acid|DRUG: Irinotecan|DRUG: Cetuximab|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised Trial Comparing the Ovarian Response of a Starting Dose of Either 10 μg or 15 μg Follitropin Delta (FE 999049) to a Starting Dose of Either 150 IU or 225 IU Follitropin Alfa (GONAL-F) in Conventional Regimens in China
Status: RECRUITING
Conditions: Infertility, Female
Interventions: DRUG: FE 999049|DRUG: GONAL-F
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a New Mechanical Ventilation Weaning Strategy for Patients With Altered Level of Consciousness
Status: COMPLETED
Conditions: Artificial Respiration|Consciousness Disorders|Wearing Off Effect
Interventions: PROCEDURE: mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrospective Analysis of Colorectal Cancer Screening Results
Status: COMPLETED
Conditions: Colorectal Cancer|Advanced Adenocarcinoma|Hyperplastic Polyp|Colorectal Neoplasms|Digestive System Neoplasm|Neoplasms
Interventions: DIAGNOSTIC_TEST: SDC2 Gene Methylation Test and Q-FIT Test|PROCEDURE: Colonoscopy and/or pathological examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Portal Vein Tumor Thrombus After Hepatocellular Carcinoma Resection
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: TACE|PROCEDURE: Laser ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictors of Occult Atrial Fibrillation in 171 Patients With Cryptogenic TIA and Minor Stroke
Status: COMPLETED
Conditions: Cryptogenic Transient Ischemic Attack and Minor Stroke
Interventions: PROCEDURE: Holter 21 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety and Efficacy of Replenine®-VF in Haemophilia B Patients Under the Age of 6 Years
Status: COMPLETED
Conditions: Haemophilia B
Interventions: BIOLOGICAL: Replenine®-VF (High Purity Factor IX)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Clinical Study to Evaluate Pharmacokinetic Profiles and Safety of CKD-387 Under Fasting Condition
Status: COMPLETED
Conditions: Endocrine, Nutritional and Metabolic Diseases
Interventions: DRUG: CKD-387|DRUG: D484
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SM-13496 (Lurasidone HCl) in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: SM-13496 (lurasidone HCl)|DRUG: SM-13496 (lurasidone HCl)|DRUG: Placebo|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study
Status: COMPLETED
Conditions: Emergence Reaction|Procedural Sedation
Interventions: DRUG: Inhaled Nitrous Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Ribavirin With Sofosbuvir/Velpatasvir/Voxilaprevir in Retreatment of Chronic Hepatitis C Non-responders
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Sofosbuvir / Velpatasvir / Voxilaprevir Oral Tablet [Vosevi] plus Ribavirin|DRUG: Sofosbuvir / Velpatasvir / Voxilaprevir Oral Tablet [Vosevi]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating Pharmacogenomics-informed Pharmacotherapy Versus Dosing as Usual in Psychiatric Disorders
Status: RECRUITING
Conditions: Mood Disorders|Anxiety Disorders|Psychotic Disorders
Interventions: OTHER: Personalised medication advice based on pharmacogenetic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH)
Status: COMPLETED
Conditions: Acne Vulgaris|Post Inflammatory Hyperpigmentation
Interventions: DRUG: Azelaic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced or Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: Lazertinib|DRUG: Amivantamab Subcutaneous and Co-Formulated with Recombinant Human Hyaluronidase (SC CF)|DRUG: Amivantamab Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Mindfulness-based Program for Parents of Children With Autism
Status: RECRUITING
Conditions: Mindfulness|Psychophysiologic Reaction|Behavior, Health
Interventions: BEHAVIORAL: Online Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Determination of Risk Factors of Ventricular Arrhythmias (VAs) After Implantation of Continuous Flow Left Ventricular Assist Device With Continuous Flow Left Ventricular Assist Device (CF-LVAD)
Status: COMPLETED
Conditions: Severe Cardiac Insufficiency
Interventions: OTHER: Implantable cardioverter-defibrillator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics of BV100 in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: BV100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Long-term Safety and Tolerability and the Long-term Effectiveness of Extended-release Oral Paliperidone in Patients Diagnosed With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone ER Oros
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-procedural Mouthwash in Reducing Bacteria in Dental Aerosols
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Dental prophylaxis|DRUG: Mouthwash CPC+Zn+F|DRUG: Mouthwash CHX|OTHER: No rinsing|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Low Flow Anaesthesia, is There a Difference Between 2 Modern Anaesthetic Machines Using Different Gas Reservoir
Status: TERMINATED
Conditions: General Anaesthesia
Interventions: DEVICE: Flow-I, a modern anaesthetic machine without a bag/below/gas reservoir for compression of insufflation gas|DEVICE: Asys, a anaesthetic machine with a bag/bellow for compression of gas to be insufflated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hemodynamic Effect of Lumbosacral Plexus Blockade Versus Spinal Anesthesia
Status: TERMINATED
Conditions: Total Hip Replacement
Interventions: PROCEDURE: Ropivacaine|PROCEDURE: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer|Anaplastic Thyroid Cancer|Undifferentiated Thyroid Cancer
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Outcomes Following LASIK Surgery Using CustomVue
Status: COMPLETED
Conditions: Myopia|Astigmatism|Myopic Astigmatism
Interventions: DEVICE: Wavefront-guided LASIK using CustomVue platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Measurement Using Infrared Camera and Electrical Impedance Tomography for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia
Status: RECRUITING
Conditions: Patients Undergoing Transurethral Prostate or Cystectomy Under Spinal Anesthesia
Interventions: DEVICE: IR Camera|DEVICE: Electrical Impedance Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients
Status: COMPLETED
Conditions: Pain|Cancer
Interventions: DRUG: Morphine Sulphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of NOTES-TME Versus L-LAR in Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: TRANSANAL TOTAL MESORECTAL EXCISION|PROCEDURE: Laparoscopic-LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FAZA PET/MRI Pancreas
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma Non-resectable|Locally Advanced Pancreatic Adenocarcinoma|Unresectable Pancreatic Cancer
Interventions: DRUG: 18F-FAZA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Transhepatic Arterial Chemotherapy (TAC) Versus Transcatheter Arterial Chemoembolization (TACE) Plus Folfox4 as the Treatment of Unresectable Liver Metastasis of Colorectal Cancer
Status: UNKNOWN
Conditions: Liver Metastasis|Colorectal Cancer
Interventions: PROCEDURE: TACE + folfox 4|PROCEDURE: TAC + folfox4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iodine Supplementation in Graves' Hyperthyroidism
Status: NOT_YET_RECRUITING
Conditions: Graves Disease|Hyperthyroidism
Interventions: DIETARY_SUPPLEMENT: Iodine Supplementation in Whole Course of Treatment with ATDs|DIETARY_SUPPLEMENT: Iodine Supplementation During Maintenance Treatment with ATDs|DIETARY_SUPPLEMENT: Iodine Restriction in Whole Course of Treatment with ATDs|DRUG: anti-Thyroid Drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Spreader Grafts in Reduction Rhinoseptoplasty: a Randomized Clinical Trial With Quality of Life Assessment
Status: UNKNOWN
Conditions: Rhinoplasty|Nasal Obstruction
Interventions: PROCEDURE: Spreader Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Pharmacokinetic Study of Lorcaserin Hydrochloride in Obese Pediatric Subjects 6 to 11 Years of Age
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Lorcaserin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PL9643 Ophthalmic Solution in Subjects With Dry Eye
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: PL9643 Ophthalmic Solution|DRUG: Placebo Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4, Randomized, Double-blind, Parallel-group, Comparative Study and a Phase 4, Open-label, Long-term Study of SYR-472 (100 mg) in Combination With Insulin in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: SYR-472|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Support Through Remote Observation and Nutrition Guidance Program for Individuals With Gastroesophageal Cancer
Status: RECRUITING
Conditions: GastroEsophageal Cancer
Interventions: BEHAVIORAL: Dietitian Consultation|BEHAVIORAL: Survey|BEHAVIORAL: Fitbit Data Collection|BEHAVIORAL: Referral to Dietitian|BEHAVIORAL: Social Determinants of Health Survey (SDOH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neutrophils to Lymphocytes Ratio in Predicting the Response to BCG in Non-muscle Invasive Bladder Cancer
Status: COMPLETED
Conditions: Urinary Bladder Cancer|Urinary Bladder Neoplasm|BCG|Trans Urethral Resection of a Bladder Tumor|Non-Muscle Invasive Bladder Urothelial Carcinoma
Interventions: DIAGNOSTIC_TEST: Neutrophil to lymphocyte ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Incoxil Food Supplement in Female Patients With Stress Dominant Urinary Incontinence.
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DIETARY_SUPPLEMENT: Incoxil food supplement and pelvic floor muscle exercise|OTHER: Pelvic floor muscle exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: MRI Anastomotic Integrity of Pelvic Intestinal Anastomoses
Status: COMPLETED
Conditions: Ulcerative Colitis|Ileal Pouch|Anastomotic Leak
Interventions: DIAGNOSTIC_TEST: Dynamic MRI enema|DIAGNOSTIC_TEST: Fluoroscopic enema
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Desensitizers in Reducing Post-operative Sensitivity Following Composite Restorations
Status: COMPLETED
Conditions: Sensitivity
Interventions: COMBINATION_PRODUCT: Gluma desensitiser|COMBINATION_PRODUCT: Sheildforce Plus desensitiser|COMBINATION_PRODUCT: Telio CS desensitiser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy Adults
Status: COMPLETED
Conditions: West Nile Fever
Interventions: BIOLOGICAL: ChimeriVax-WN02 Low Dose|BIOLOGICAL: ChimeriVax-WN02 Medium Dose|BIOLOGICAL: ChimeriVax-WN02 High Dose|BIOLOGICAL: 0.9% Saline solution|BIOLOGICAL: ChimeriVax-WN02 High Dose|BIOLOGICAL: 0.9 % NaCl solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Butyrate and Palmitoylethanolamide in IBS Patients (B/P3_1)
Status: ENROLLING_BY_INVITATION
Conditions: Irritable Bowel Syndrome With Diarrhea
Interventions: DIETARY_SUPPLEMENT: ButirBioma + PeaBioma|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of JNJ-39758979 in the Treatment of Adults With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: JNJ39758979|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ATX Study:A Study of Avastin (Bevacizumab), Tarceva (Erlotinib) and Xeloda (Capecitabine) in Patients With Locally Advanced and/or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: capecitabine [Xeloda]|DRUG: erlotinib [Tarceva]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of Using Supportive Postures and Holding Techniques to Minimize Premature Infant Pain (PAP)
Status: SUSPENDED
Conditions: Premature Infant
Interventions: OTHER: Installation of a naso-gastric feeding tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxandrolone Multiligament Knee
Status: RECRUITING
Conditions: Ligament Tear Knee
Interventions: DRUG: Oxandrolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gingival Response and Marginal Adaptation of Zirconia Crowns With Two Subgingival Margin Designs
Status: UNKNOWN
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Feather edge finish line preparation|PROCEDURE: Deep chamfer finish line preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoral Scanning v.s Desktop Scanning
Status: COMPLETED
Conditions: Edentulous Jaw
Interventions: PROCEDURE: intraoral scanning|PROCEDURE: Desktop scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Retreatment of Chronic Hepatitis C Non-responders With Pegylated Interferon Alpha Plus Ribavirin Plus Pioglitazone
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Pioglitazone|DRUG: Interferon Alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Single Centre, Double-blind, Parallel, Sham-controlled Pilot Study Using gammaCore®-G
Status: COMPLETED
Conditions: Dyspepsia|Irritable Bowel Syndrome
Interventions: DEVICE: gammaCore®-G
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: BENEFIT OF MECHANICAL ISCHEMIC PRECONDITIONING ON TOLERANCE OF ADIPOSE TISSUE TO ISCHEMIA REPERFUSION OF TYPE DIEP (DEEP INFERIOR EPIGASTRIC PERFORATOR) FREE FLAPS.
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: Mechanical ischemic preconditioning of diep-type flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma Multiforme, Adult
Interventions: DRUG: Berubicin|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Mucosal Injection Versus Ultrasound-Guided Injection of Triamcinolone to Treat Subglottic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Subglottic Stenosis
Interventions: PROCEDURE: Ultrasound-Guided|PROCEDURE: Translaryngeal Endoscopic Mucosal Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy
Status: COMPLETED
Conditions: Narcolepsy With Cataplexy
Interventions: DRUG: Xyrem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tiotropium/Formoterol Via Discair® vs Tiotropium Monotherapy or Tiotropium + Formoterol Free Combination Treatment
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Tiotropium/Formoterol|DRUG: Tiotropium|DRUG: Formoterol|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Effectiveness and Safety of Closed-Loop Spinal Cord Stimulation in Treating Patients With Chronic Pelvic Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DEVICE: ECAP (Evoked Compound Action Potential)-controlled Closed-Loop Spinal Cord Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells in Patients With Alzheimer's Disease
Status: WITHDRAWN
Conditions: Alzheimer's Disease
Interventions: PROCEDURE: Liposuction under local anesthesia|BIOLOGICAL: Infusion of AD-SVF via IV and Intranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Feasibility of Implementing a Coordinated Hospital/Non-hospital Parenting Support and Prevention Program for Families of Infants at High Neurodevelopmental Risk After Neonatal Intensive Care Hospitalization
Status: RECRUITING
Conditions: Neurodevelopmental Motor Disorders
Interventions: OTHER: Focus group (FC) - WP1|OTHER: Child Neurodevelopment Questionnaires - WP2|OTHER: Evaluation of compliance for the acquired skills in terms of development support - WP2|OTHER: Evaluation of physiotherapist satisfaction with the follow-up and the time spent at the consultation - WP2|OTHER: 4 Focus Group (FC) - WP2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Delto-Tricipital Compression Syndrome: Treated With Injection of Dextrose
Status: UNKNOWN
Conditions: Superficial Radial Nerve Lesion
Interventions: DRUG: Dextrose 5% (D5W)|OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarkers in Patients With Head and Neck Cancer and in Healthy Volunteers
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: protein expression analysis|GENETIC: proteomic profiling|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of the Treatment of Intellectual Metastases by Radiosurgery Gamma Knife by Means of a Support System by Mask.
Status: COMPLETED
Conditions: Lung Cancer|Brain Metastases
Interventions: DEVICE: GammaKnifePerfexion®|DEVICE: GammaKnifeIcon®|DEVICE: Efficast®|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Instant Message Intervention for Psychological Well-being Among Stroke Survivors
Status: COMPLETED
Conditions: Stroke|Depressive Symptoms|Mobile Phone Use
Interventions: OTHER: iCBT-based EMI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Flumazenil Antagonism of Remimazolam in Kidney Transplant Patients
Status: NOT_YET_RECRUITING
Conditions: Flumazenil to Antagonize Remimazolam|Remimazolam|Renal Transplantation
Interventions: DRUG: Flumazenil Injection（F1 group）|DRUG: Flumazenil Injection（F2 group）|DRUG: Saline（C group）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Cessation Study for Patients With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: placebo|DRUG: varenicline (CP-526,555)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Trial of a Botulinum A Toxin (Botox) Injection in the Gastrocnemius Muscle in Children With Idiopathic Toe Walking
Status: COMPLETED
Conditions: Idiopathic Toe Walking
Interventions: DRUG: Botox injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of tDCS on Inflammatory Biomarkers in Chronic Schizophrenia
Status: RECRUITING
Conditions: Chronic Schizophrenia
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impacts of the Different Anesthesia Methods on Patients of Transbronchial Cryobiopsy
Status: UNKNOWN
Conditions: Transbronchial Cryobiopsy|Anesthesia|Tracheal Intubation|Rigid Bronchoscopy|Safety
Interventions: PROCEDURE: anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Action Toward Obesity Prevention (SHARE-AP Action)
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Health messaging at weekly home visits by health counsellor|BEHAVIORAL: Weekly home delivery of bottled spring water|BEHAVIORAL: Weekly afterschool physical activity program for 5-18y.o.|BEHAVIORAL: Cooking classes and grocery store tours with dietician|BEHAVIORAL: Pedometers to track/increase weekly physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Nab-Paclitaxel and S-1 in Borderline Resectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Borderline Resectable Pancreatic Cancer
Interventions: DRUG: nab-paclitaxel and S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Loncastuximab Tesirine in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma Refractory|Diffuse Large B-cell Lymphoma Recurrent
Interventions: DRUG: Loncastuximab tesirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies
Status: TERMINATED
Conditions: Sickle Cell Anemia|Hemoglobinopathy|Thalassemia
Interventions: DRUG: Campath -1H|DRUG: Dilantin|DRUG: Busulfan|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Pregabalin to Decrease Pain During Medical Abortion
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Sunitinib Malate as a Component of Neoadjuvant Therapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: sunitinib alone|DRUG: sunitinib plus paclitaxel|DRUG: doxorubicin and cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Rosnilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT