pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety, Efficacy, and Pharmacokinetics of Adalimumab in Japanese Children With Juvenile Rheumatoid Arthritis
Status: COMPLETED
Conditions: Juvenile Rheumatoid Arthritis
Interventions: BIOLOGICAL: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use and Tolerability of Imatinib Mesylate (Gleevec) in Leukemia Patients
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin in Patients With Type 2 Diabetes With HbA1c 9-11%
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: High-Risk Skin Cancers With Atezolizumab Plus NT-I7
Status: TERMINATED
Conditions: Melanoma|Merkel Cell Carcinoma|Cutaneous Squamous Cell Carcinoma
Interventions: DRUG: NT-I7|DRUG: atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IBI362 9 mg in Chinese Adults With Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: IBI362|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alendronate in Chinese Children or Adolescents With Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Universal Exercise Unit Therapy With Sling Exercise Therapy on Lower Limb Kinematics in Chronic Stroke Patients
Status: RECRUITING
Conditions: Chronic Stroke
Interventions: OTHER: Universal Exercise Unit Therapy (UEU)|OTHER: Sling Exercise Therapt (SET)|OTHER: Routine Physical Therapy / Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine lozenge|DRUG: Nicotine lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Status: COMPLETED
Conditions: Depression, Anxiety|Alcohol Abuse|Sexual Compulsivity|Unsafe Sex
Interventions: BEHAVIORAL: ESTEEM (Effective Sikills to Empower Effective Men)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mostafa Maged Four-stitch Technique in Closure the Episiotomy During Vaginal Delivery
Status: UNKNOWN
Conditions: Vaginal Delivery|Suture, Complication|Tear; Cervix|Hematoma|Ecchymosis
Interventions: PROCEDURE: patients of controlled group with routine closure of episiotomy|PROCEDURE: The Mostafa Maged four-stitch technique fore closure of the episiotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Trial of Xyrem® (Sodium Oxybate) for the Treatment of Narcolepsy
Status: COMPLETED
Conditions: Narcolepsy
Interventions: DRUG: Xyrem (sodium oxybate) oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate Safety, Efficacy, and Pharmacokinetics in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Renal Cell Cancer Metastatic|Non-Small Cell Lung Cancer|Renal Cell Carcinoma|Prostate Cancer
Interventions: DRUG: EU101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Interventions: DRUG: Tolvaptan|DRUG: Tolvaptan Matching-placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Mesenchymal Stem Cells for Patients With Primary Biliary Cirrhosis
Status: UNKNOWN
Conditions: Primary Biliary Cirrhosis
Interventions: OTHER: conventional plus UC-MSC treatment|OTHER: Conventional plus placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A High-PRotein Mediterranean Diet and Resistance Exercise for Cardiac Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Diseases|Sarcopenic Obesity
Interventions: OTHER: High-Protein Mediterranean Diet|OTHER: Resistance Exercise|OTHER: Standard Dietary Advice|OTHER: Standard Cardiac Rehabilitation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Pomegranate Seed Oil on Postprandial Cardiovascular Disease Risk Markers
Status: RECRUITING
Conditions: Postmenopausal Women
Interventions: DIETARY_SUPPLEMENT: Pomegranate seed oil|DIETARY_SUPPLEMENT: Mixed vegetable oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: DRUG: D-cycloserine|BEHAVIORAL: Exposure and Response Prevention (EX/RP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dupilumab for Eosinophilic Esophagitis With Severe Strictures
Status: RECRUITING
Conditions: Eosinophilic Esophagitis|EoE
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: PET MPI|DRUG: SPECT MPI|DRUG: Pharmacological stress agents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Relationship Between Serum Chemokine Ligand 21 (CCL-21) Level and Disease Activity
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis|Osteoarthritis
Interventions: DIAGNOSTIC_TEST: Laboratory tests (examination)|DIAGNOSTIC_TEST: Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index|DIAGNOSTIC_TEST: The Disease Activity Score28 (DAS28)|DIAGNOSTIC_TEST: Patient global assessment (PGA)|DIAGNOSTIC_TEST: Physician global assessment (PhGA)|DIAGNOSTIC_TEST: Health Assessment Questionnaire (HAQ)|DIAGNOSTIC_TEST: Clinical disease activity index (CDAI)|DIAGNOSTIC_TEST: The Simplified Disease Activity Index (SDAI)|DIAGNOSTIC_TEST: Knee Radiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Capecitabine and GTI-2040 in the Treatment of Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Metastases, Neoplasm
Interventions: DRUG: GTI-2040
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of GFA-918 on Serum Triglyceride Levels in Individuals With Elevated Serum Triglyceride
Status: COMPLETED
Conditions: Elevated Triglycerides
Interventions: DIETARY_SUPPLEMENT: GFA-918|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Phase I Study of MSB2311 in Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: 3 mg/kg Q3W MSB2311 Injection|DRUG: 10 mg/kg Q3W MSB2311 Injection|DRUG: 20 mg/kg Q3W MSB2311 Injection|DRUG: 10 mg/kg Q2W MSB2311 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)
Status: COMPLETED
Conditions: Bilateral Cataract
Interventions: DEVICE: ACRYSOF® Single-Piece NATURAL Toric IOL Model SN60T9 and Model SN60T8.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma
Status: TERMINATED
Conditions: Lung Adenocarcinoma
Interventions: DRUG: L-DOS47|DRUG: Cisplatin|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Bevacizumab and Pemetrexed in Patients With Untreated, Advanced Non-Small Cell Lung Cancer Using Web-Based Data Collection, Patient Self-Reporting of Adverse Effects and Automated Response Assessment
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMS-188667 in Children and Adolescents With Juvenile Rheumatoid Arthritis
Status: COMPLETED
Conditions: Juvenile Rheumatoid Arthritis
Interventions: DRUG: Abatacept|DRUG: Placebo|DRUG: Abatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Bydureon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Registry of Patients Treated With Plerixafor (Mozobil®) for Haematopoietic Stem Cell Mobilization Before Autologous Transplantation
Status: COMPLETED
Conditions: Bone Marrow / Autologous Transplants
Interventions: DRUG: Plerixafor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Pharmacokinetic and Pharmacodynamic Bioequivalence of CHS-1701 With Neulasta
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CHS-1701|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: SPI-1005 Treatment in Severe COVID-19 Patients
Status: ENROLLING_BY_INVITATION
Conditions: Covid19|Coronavirus|Coronavirus Infection|Corona Virus Infection
Interventions: DRUG: Ebselen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Rapid Recovery Protocol in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Fast Track|Tranexamic Acid Adverse Reaction|Knee Osteoarthritis
Interventions: BEHAVIORAL: Walk within 24 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Radiation Therapy in Treating Patients With Stage II Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: RADIATION: Conventional 3D-CRT or IMRT|RADIATION: Hypofractionated 3D-CRT or IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome
Status: COMPLETED
Conditions: Atypical Hemolytic-Uremic Syndrome
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Locally Advanced Malignant Solid Neoplasm|Locally Advanced Melanoma|Metastatic Malignant Solid Neoplasm|Metastatic Melanoma|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Malignant Solid Neoplasm|Unresectable Melanoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Dabrafenib Mesylate|PROCEDURE: Magnetic Resonance Imaging|DRUG: Trametinib Dimethyl Sulfoxide|DRUG: Uprosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experienced Chinese Herbal Formulas on Pediatric Asthma
Status: COMPLETED
Conditions: Childhood Asthma
Interventions: DRUG: experienced chinese herbal formulas|DRUG: leukotriene receptor antagonist and bronchial relaxant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects
Status: COMPLETED
Conditions: Drug Safety
Interventions: DRUG: Placebo|DRUG: VIA-3196
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Four-hour Glycemic Kinetic Response Following 13C-enriched Oatmeal Breakfast Compared to Hot Corn Grits
Status: COMPLETED
Conditions: Glycemic and Insulinemic Response
Interventions: OTHER: Oatmeal|OTHER: Corn grits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Automatic Self Transcending Meditation (ASTM) Versus Heart Rate Variability (HRV) Biofeedback in Patients With Late Life Depression (LLD): a Longitudinal Pilot Feasibility Study
Status: COMPLETED
Conditions: Late Life Depression
Interventions: BEHAVIORAL: HRV biofeedback|BEHAVIORAL: ASTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unravelling the Etiology of Shoulder Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis of the Shoulder
Interventions: RADIATION: Low-dose CT|OTHER: T1Rho MRI|OTHER: Motion Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Esketamine and Perioperative Depressive Symptoms
Status: RECRUITING
Conditions: Depressive Symptoms|Esketamine|Perioperative Complication|Major Surgery
Interventions: DRUG: Esketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of MT-0169 in CD38+ Acute Leukemia With Relapsed/Refractory or Measurable Residual Disease
Status: NOT_YET_RECRUITING
Conditions: Leukemia
Interventions: DRUG: MT-0169
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of Intermittent Fasting
Status: RECRUITING
Conditions: Normal and Overweight Individuals at High-risk of Diabetes
Interventions: BEHAVIORAL: Fasting arm|BEHAVIORAL: Weight maintenance|BEHAVIORAL: Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long Term Follow-Up of Food and Cash Assistance for HIV-Positive Men and Women on Antiretroviral Therapy in Tanzania
Status: COMPLETED
Conditions: Hiv
Interventions: BEHAVIORAL: Incentive for linkage to care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of PEMF Therapy for Female Patients With IC/BPS
Status: RECRUITING
Conditions: Interstitial Cystitis|Chronic Interstitial Cystitis|Bladder Pain Syndrome
Interventions: DEVICE: Pulsed Electromagnetic Field (PEMF) Device|DEVICE: Sham Pulsed Electromagnetic Field (PEMF) Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Darolutamide as a Prostate-Specific Membrane Antigen (PSMA) Expression Enhancer in Patients With Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Darolutamide Oral Tablet [Nubeqa]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Traumeel® S in Preventing and Treating Mucositis in Young Patients Undergoing Stem Cell Transplantation
Status: COMPLETED
Conditions: Kidney Cancer|Leukemia|Lymphoma|Neuroblastoma|Oral Complications|Sarcoma
Interventions: DRUG: Traumeel S|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gene Electrotransfer to Muscle With Plasmid AMEP in Patients With Disseminated Cancer
Status: TERMINATED
Conditions: Metastatic Malignant Neoplasm
Interventions: DRUG: Plasmid AMEP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group Therapy With Transcranial Direct Current Stimulation in Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: OTHER: GTO|OTHER: GT-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Strength Cranberry Supplementation for Prevention of Recurrent Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DIETARY_SUPPLEMENT: High Strength Cranberry|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevent Return of Stroke Study
Status: COMPLETED
Conditions: Stroke Recurrence|Transient Ischemic Attack
Interventions: BEHAVIORAL: Prevent Return of Stroke|BEHAVIORAL: Prevent Return of Stroke
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels
Status: TERMINATED
Conditions: Acute Exacerbation of COPD|Corticosteroid|Morality|Lung Diseases, Obstructive|Blood Eosinophil Count|COPD|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Regulated Pleural Pressure on Air Leak and Fluid Drainage Following Pulmonary Resections: A Multicenter Randomized Trial
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: PROCEDURE: Switching level of suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Leucine on Body Composition and Muscle Characteristics in Elderly, Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Wheat flour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose:
Clinical trial: Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections
Status: COMPLETED
Conditions: IgG Deficiency|Infections
Interventions: DRUG: IV Gamunex 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Nalbuphine as an Adjuvant to Intrathecal Bupivacaine
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Dexmedetomidine|DRUG: Nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Effects of Four-week Lactate-ketone Ester Supplementation
Status: RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: LaKe Ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Metformin Treatment on Cognitive Impairment of Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Metformin treatment|DRUG: Placebo treatment|OTHER: Baseline assessments|OTHER: Volunteer assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Therapy With Bevacizumab in Chronic Central Serous Chorioretinopathy
Status: UNKNOWN
Conditions: Central Serous Chorioretinopathy
Interventions: PROCEDURE: intravitreal injection with anterior paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Safety and Efficacy of Bio-Active Silver Hydrosol™ in Providing Immune Support
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Silver Hydrosol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Contribution of the ENT (Ear, Nose, and Throat) Surgeon's Clinical Evaluation to the Contouring of Target Volumes and Organs Eligible for Radiotherapy in Head and Neck Cancers
Status: COMPLETED
Conditions: Radiotherapy, Conformal (IMRT)|Head and Neck Cancer|Otolaryngology|Surgeons|Radiation Oncologists
Interventions: OTHER: Systematic consideration of the advice of the ENT surgeon in the determination of the radiotherapy target volumes in head and neck cancers.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Biobanking Study in Ovarian, Breast, Head and Neck and Cervical Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)
Status: RECRUITING
Conditions: Ovarian Cancer|Triple-Negative Breast Cancer|Head and Neck Cancer|Cervical Cancer
Interventions: PROCEDURE: Tumor biopsies / Tumor surgery|PROCEDURE: Blood withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Do Corticosteroid Injections During Total Knee Replacement Improve Early Clinical Results?
Status: COMPLETED
Conditions: Osteoarthritis|Post-traumatic; Arthrosis
Interventions: DRUG: methylprednisolone acetate|DRUG: active comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Efficacy and Safety of Ustekinumab in Patients With Primary Biliary Cirrhosis (PBC) Who Had an Inadequate Response to Ursodeoxycholic Acid
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DRUG: ustekinumab 90 mg|DRUG: ustekinumab 45 mg|DRUG: ustekinumab 180 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Toric Intraocular Lens(IOL) Combined with Capsular Tension Ring(CTR) in Patients with Cataract Combined with High Myopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Cataract|Astigmatism|Intraocular Lens Rotation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BMS-214662 in Treating Patients With Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: BMS-214662|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The "CAD-Man" EXTEND Study
Status: ENROLLING_BY_INVITATION
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: CT|DIAGNOSTIC_TEST: invasive coronary angiography (ICA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Intermittent Oral Dosing of ASP1517 in Non-Dialysis Chronic Kidney Disease Patients With Anemia
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: roxadustat|DRUG: DA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of SHR7390 in Combination With SHR-1210 and SHR3162 in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor
Interventions: DRUG: SHR7390|BIOLOGICAL: SHR-1210|DRUG: SHR3162
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: Rapamycin|PROCEDURE: Surgery|PROCEDURE: Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASSIP, Attempted Suicide Short Intervention Program. Two Year Follow-Up Study
Status: COMPLETED
Conditions: Suicide Attempt|Suicide|Suicidal Ideation
Interventions: BEHAVIORAL: Attempted Suicide Short Intervention Program (ASSIP)|BEHAVIORAL: Control Group (CG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography Imaging Using Copper Cu 64 TP3805 in Patients With Breast Cancer
Status: TERMINATED
Conditions: Breast Carcinoma
Interventions: DEVICE: Positron Emission Mammography|DEVICE: Positron Emission Tomography|RADIATION: Fludeoxyglucose F-18|DRUG: Copper Cu 64 TP3805
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: So-Lo-Mo Intervention Applied to the Smoking Cessation Process
Status: COMPLETED
Conditions: Smoking Cessation|Health Behavior|Lifestyle-related Condition
Interventions: OTHER: So-Lo-Mo|BEHAVIORAL: Psychological advice|DRUG: Bupropion Pill|DRUG: Varenicline Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exemestane or Anastrozole in Treating Postmenopausal Women Who Have Undergone Surgery for Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Secondary Care - Prescribing Lifestyle Adjustments for Cardiovascular Health (S-PLAC 2)
Status: SUSPENDED
Conditions: Cardiovascular Diseases|Cardiovascular Risk Factor|Health Behavior
Interventions: BEHAVIORAL: Lifestyle Prescription (LRx)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency
Status: COMPLETED
Conditions: Growth Hormone Deficiency|Endocrine System Diseases|Hormone Deficiency
Interventions: DRUG: Lonapegsomatropin|OTHER: Placebo|DRUG: Somatropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nitroglycerin on the Intrauterine Device (IUD) Insertion Experience in Nulliparous Women
Status: COMPLETED
Conditions: Contraception|Pain
Interventions: DRUG: Insertion of nitroglycerin ointment|DRUG: Insertion of placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Tolerability of Fentanyl Iontophoretic Transdermal System (Fentanyl-ITS) in the Management of Post-Surgery Pain
Status: TERMINATED
Conditions: Postoperative Pain
Interventions: DRUG: Fentanyl-ITS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: D2 vs D3 Lymph Node Dissection for Left Colon Cancer
Status: RECRUITING
Conditions: Colon Cancer
Interventions: PROCEDURE: Left colon resection|PROCEDURE: Sigmoid colon resection|PROCEDURE: Distal sigmoid colon resection or anterior resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Almond Milk With Vitamin D: Impact on Vitamin D Status
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic|Kidney Failure, Chronic
Interventions: DIETARY_SUPPLEMENT: NanoD4CKD|DIETARY_SUPPLEMENT: MicroD4CKD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: POWER: Pulse Intravascular Lithotripsy (Pulse IVL) to Open Vessels With Calcific Walls and Enhance Vascular Compliance and Remodeling
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Pulse Intravascular Lithotripsy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Investigation of Glucose Monitoring After Gestational Diabetes Pilot
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes|Hyperglycemia
Interventions: DEVICE: Dexcom G6/G7 CGM|DIAGNOSTIC_TEST: Oral Glucose Tolerance Test|DIAGNOSTIC_TEST: Hemoglobin A1c
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Atorvastatin on Disease Activity and HDL Cholesterol Function in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Breast Imaging as a Screening Tool for Women With Dense Breasts
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Molecular Breast Imaging|DEVICE: Conventional Mammography|DRUG: Technetium (99mTc) sestamibi
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Ketamine for Pain Relief in Bariatric Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Fentanyl|DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Three Dimensional Versus Two Dimensional Laparoscopic Salpingectomy in Patients With Hydrosalpinx Undergoing IVF-ET
Status: COMPLETED
Conditions: Hydrosalpinx
Interventions: BIOLOGICAL: Laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis
Status: NOT_YET_RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Methotrexate Combined With Tofacitinib|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Randomized, Double-blind, Placebo-controlled Crossover Study of RG7314 on the Potential Regulation of Higher Brain Functions in Healthy Male Participants: Proof of Mechanism
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Placebo RD + AVP SD|DRUG: Placebo RD + Placebo SD|DRUG: RG7314 RD + AVP SD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose Selection Study of Efficacy and Safety of Different Doses of Grass MATA MPL and Grass MATA Using mEECs™
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: BIOLOGICAL: Placebo (0.5ml)|BIOLOGICAL: Placebo (1.0ml)|BIOLOGICAL: Grass MATA MPL (0.5ml) 5100SU|BIOLOGICAL: Grass MATA MPL (1.0ml) 10200SU|BIOLOGICAL: Grass MATA MPL (1.0ml) 18200SU|BIOLOGICAL: Grass MATA (0.5ml) 5100SU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Oncostatin M, Leukemia Inhibitory Factor and Interleukin-11 Levels of Patients With Periodontal Disease
Status: COMPLETED
Conditions: Chronic Periodontitis, Generalized|Gingivitis
Interventions: PROCEDURE: Initial Periodontal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study to Describe the Safety and Immunogenicity of a RSV Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Tract Infections
Interventions: BIOLOGICAL: Formulation A|BIOLOGICAL: Formulation B|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of AP-CD/LD in Fluctuating Parkinson's Disease Patients Who Completed IN 11 004
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DRUG: Accordion Pill™ Carbidopa/Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure for Primary Care (PE-PC)|BEHAVIORAL: EAP Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Ablation Device Comparison Study
Status: WITHDRAWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: Dry bipolar radiofrequency (RF) clamp|DEVICE: Unipolar microwave antenna|DEVICE: Unipolar cryothermic probe|DEVICE: Irrigated unipolar RF antenna|DEVICE: Irrigated bipolar RF clamp|DEVICE: Hi-intensity focused ultrasound wand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Tigecycline Versus Clindamycin Or Vancomycin On Complicated Skin And Skin Structure Infections Including Those Due To Methicillin-Resistant Staphylococcus Aureus (MRSA) In Pediatric Subjects
Status: WITHDRAWN
Conditions: Skin Diseases|Infection
Interventions: DRUG: Tigecycline|DRUG: Clindamycin (or Vancomycin if needed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy of Food Supplement Manremyc® Against SARS- COV-2 Infection (COVID-19) in Healthcare Workers
Status: UNKNOWN
Conditions: COVID19
Interventions: DIETARY_SUPPLEMENT: Manremyc|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Tooth Mousse to Remineralise Post-orthodontic Treatment White Spot Lesions
Status: COMPLETED
Conditions: Demineralisation|White Spot Lesions|Orthodontic Treatment
Interventions: DEVICE: Tooth Mousse creme (Casein Phosphopeptide)(RECALDENT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in Combination
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: A1: Etoricoxib / Tramadol Fixed dose combination|DRUG: A2: Etoricoxib|DRUG: A3: Tramadol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychoeducation of Parents to Children With FASD
Status: NOT_YET_RECRUITING
Conditions: Fetal Alcohol Spectrum Disorders|Behavior Problem|Adaptive Behavior|Learning Disorders
Interventions: BEHAVIORAL: Program of psychoeducation of parents and professionals
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Cosibelimab in Subjects With Relapsed or Refractory Lymphoma
Status: TERMINATED
Conditions: B-cell Non Hodgkin Lymphoma|Richter's Transformation
Interventions: DRUG: Cosibelimab|DRUG: Cosibelimab + Ublituximab + Bendamustine combination|DRUG: Cosibelimab + Ublituximab + Bendamustine combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic Renal Cell Carcinoma
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study for T-1101 (Tosylate) to Treat Advanced Refractory Solid Tumors
Status: COMPLETED
Conditions: Advanced Refractory Solid Tumors
Interventions: DRUG: T-1101 (Tosylate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Financial Incentives And Nurse Coaching to Enhance Diabetes Outcomes (FINANCE-DM)-1
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: FINANCE-DM|BEHAVIORAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dehydroepiandrosterone (DHEA) + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women
Status: COMPLETED
Conditions: Vasomotor Symptoms|Hot Flushes
Interventions: DRUG: Placebo|DRUG: DHEA and Acolbifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide once weekly|DRUG: sitagliptin|DRUG: pioglitazone|DRUG: placebo tablet|DRUG: placebo once weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of rTMS With Different Stimulation Spots in Patients With Disorders of Consciousness
Status: RECRUITING
Conditions: Disorder of Consciousness
Interventions: DEVICE: active repetitive transcranial magnetic stimulation|DEVICE: sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Through QT/QTc Study of KW-6356
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: KW-6356|DRUG: KW-6356|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Respiratory Rehabilitation on Quality of Life in Patients With Metastatic Non-small Cell Lung Cancer Treated With Immunotherapy and Chemotherapy in the Maintenance Phase
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: PROCEDURE: Respiratory Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: TLC599 LD group|DRUG: Normal Saline|DRUG: TLC599 HD group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Grass-SPIRE Registration Study
Status: WITHDRAWN
Conditions: Rhinitis|Conjunctivitis
Interventions: DRUG: Grass-SPIRE|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Relapsed or Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: single dose of CNCT19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Immediate Efficacy of Kinesiology Taping
Status: COMPLETED
Conditions: Postural; Defect
Interventions: OTHER: Kinesio Taping|OTHER: Placebo Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Can the Reduction of Iron Availability Caused by Tea Consumption Change the Gut Microbiota Composition and Disrupt Host Body-iron Status
Status: UNKNOWN
Conditions: Focus of Study: 1- Effect of Tea Consumption on Gut Microbiota|Focus of Study: 2- Effect of Tea Consumption on Body-iron Status
Interventions: DIETARY_SUPPLEMENT: Black tea|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Phase I/IIa Dose Ranging CHRONVAC-C® Study in Chronic HCV Patients
Status: UNKNOWN
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: CHRONVAC-C®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive Patients
Status: COMPLETED
Conditions: Toxoplasmosis, Cerebral|HIV Infections
Interventions: DRUG: Pyrimethamine|DRUG: Leucovorin calcium|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Porous Tissue Regenerative Silk Scaffold for Human Meniscal Cartilage Repair
Status: WITHDRAWN
Conditions: Repair of Meniscal Injury
Interventions: DEVICE: FibroFix Meniscal Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sweetgoals for Type 1 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: SweetGoals app|BEHAVIORAL: Coaching|BEHAVIORAL: Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endovascular Aortic Repair of Free and Contained Ruptured Thoraco-Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Thoracoabdominal Aortic Aneurysm|Ruptured Thoracic Aneurysm|Ruptured Aortic Aneurysm|Thoracoabdominal Aortic Aneurysm, Ruptured
Interventions: DEVICE: REVAR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p