pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Transcutaneous Electrical Nerve Stimulation for Local Anaesthesia
Status: TERMINATED
Conditions: Donor Site Complication|Skin Graft
Interventions: DEVICE: TENS machine|COMBINATION_PRODUCT: EMLA cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of APG2575 Single Agent and Combination With Therapy in Patients Relapsed/Refractory AML
Status: RECRUITING
Conditions: Relapsed/Refractory Acute Myeloid Leukaemia|Myeloid Malignancy
Interventions: DRUG: APG-2575|DRUG: Reduced-dose HHT|DRUG: standard-dose HHT|DRUG: Azacitidine|DRUG: APG-2575
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COMFORT: A Multicenter, Open-label, Randomized, Crossover Study
Status: COMPLETED
Conditions: Varicose Veins
Interventions: DRUG: Varithena®|DEVICE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of EUS-guided Biliary Drainage Using Partially or Fully Covered Metallic Stents
Status: COMPLETED
Conditions: Cholestasis, Extrahepatic
Interventions: DEVICE: EUS-BD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Topical XG004 in Participants With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: XG004|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of Sexelaxin When Added to Standard Therapy in AHF
Status: TERMINATED
Conditions: Acute Heart Failure
Interventions: DRUG: Serelaxin|DRUG: Placebo|OTHER: Standard of CareTherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Adolescent Antimuscarinic (Anticholinergic) Toxidrome
Status: COMPLETED
Conditions: Anticholinergics Toxicity
Interventions: DRUG: Physostigmine|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Low Carbohydrate Diet Versus a High Carbohydrate Diet in Promoting Weight Loss and Improved Health
Status: COMPLETED
Conditions: Obesity|Hypertension
Interventions: BEHAVIORAL: Atkins diet (low carbohydrate diet)|BEHAVIORAL: DASH diet (high carbohydrate diet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Core Stabilization Exercise With Scientific Exercise Approach to Scoliosis in Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis|Adolescent Idiopathic Scoliosis
Interventions: OTHER: SEAS exercise|OTHER: CS exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell Vaccination for Patients With Solid Tumors
Status: COMPLETED
Conditions: Glioblastoma|Renal Cell Carcinoma|Sarcomas|Breast Cancers|Malignant Mesothelioma|Colorectal Tumors
Interventions: BIOLOGICAL: autologous dendritic cell vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individual Placement and Support and/or Cognitive Remediation Therapy Added to TAU in Patients With Early Schizophrenia
Status: NOT_YET_RECRUITING
Conditions: Schizophrenia|Schizophreniform Disorders|Schizoaffective Disorder|Psychosis
Interventions: BEHAVIORAL: Individual Placement and Support|BEHAVIORAL: Cognitive Remediation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Safety of Repeated Doses of Dihydroartemisinin-Piperaquine for the Use in Mass Treatment Campaigns
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Dihydroartemisinin-piperaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Antisense Oligonucleotide to Lower Transthyretin (TTR) Levels on the Progression of -Wild-type TTR Involving the Heart
Status: WITHDRAWN
Conditions: Amyloidosis
Interventions: DRUG: Isis 420915/GSK 299872
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clopidogrel Prevention of Early Arteriovenous (AV) Fistula Thrombosis
Status: COMPLETED
Conditions: Kidney Failure|Hemodialysis Fistula Thrombosis
Interventions: DRUG: Clopidogrel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Efficacy of Different Regimens of PVPI 5% Eye Drops Instillation in Reducing Conjunctival Bacterial Flora
Status: COMPLETED
Conditions: Eye Infections
Interventions: OTHER: Povidone-iodine|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
Status: WITHDRAWN
Conditions: Metastatic Cancer|Foregut Carcinoid Tumor|Gastric Adenocarcinoma|Gallbladder Adenocarcinoma|Liver Cancer|GI Cancer|GI Carcinoma|Lung Cancer
Interventions: DRUG: Standard of Care Chemotherapy|PROCEDURE: Video-Assisted Thoracic Surgery (VATS)|PROCEDURE: Lobectomy|RADIATION: Consolidative Radiation|RADIATION: Ablation Treatment|PROCEDURE: Resection or Excision|PROCEDURE: Peritonectomy|OTHER: Transarterial Radioembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-Articular Injections of Platelet-Rich Plasma in Knee Osteoarthritis: Unique Application Versus Triple Application
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Platelet-Rich Plasma|BEHAVIORAL: rehabilitation exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sugammadex Dosing: Anaesthesiologist Clinical Perception Versus Quantitative Monitoring
Status: COMPLETED
Conditions: Neuromuscular Blockade|Anesthesia|TOF|Curarization, Postoperative Residual
Interventions: OTHER: Dose of sugammadex according to SSD and QSD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lidocaine Spray Compared With Submucosal Injection During LEEP: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Uterine Cervical Dysplasia
Interventions: PROCEDURE: Lidocaine spray|PROCEDURE: Lidocaine submucosal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Treatment for Children With Intraocular Germ-Line Retinoblastoma
Status: COMPLETED
Conditions: Retinoblastoma|Retinal Neoplasms
Interventions: DRUG: Carboplatin|DRUG: VP-16|PROCEDURE: Local Surgery|PROCEDURE: Cryotherapy|PROCEDURE: Laser hyperthermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Antioxidant Efficacy of Spirulina on oxLDL and Lipids Metabolism on Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Spirulysat®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Estradiol Vaginal Inserts 4mcg To IMVEXXY ® (Estradiol Vaginal Inerts 4 mcg) In The Treatment Of Dyspareunia in Women With Vulvur and Vaginal Atrophy
Status: COMPLETED
Conditions: Dyspareunia
Interventions: DRUG: Estradiol|DRUG: Imvexxy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A COMparison Between PAClitaxel-coated Balloon and pacliTaxel-eluting Stent in the Treatment of In-Stent Restenosis (COMPACT-ISR)
Status: TERMINATED
Conditions: Stable Angina|Unstable Angina
Interventions: PROCEDURE: Paclitaxel-coated Balloon|DEVICE: Paclitaxel-eluting Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Raltegravir (Isentress®) on Lipid and Carbohydrate Metabolism and Mitochondrial Function in Healthy Volunteers
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: raltegravir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Telavancin and Vancomycin for Hospital-acquired Pneumonia Due to Methicillin-resistant Staphylococcus Aureus
Status: COMPLETED
Conditions: Bacterial Pneumonia
Interventions: DRUG: Telavancin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating ABT-199 in Participants With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: DRUG: Venetoclax|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Immune Response, and Efficacy of Gardasil (V501, qHPV) in Mid-Adult Women (V501-019)
Status: COMPLETED
Conditions: Healthy Adult Female Participants|Prevention|Papillomavirus Infection|Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine|BIOLOGICAL: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory Study of the Safety, Tolerability and Efficacy of Multiple Regimens of Natalizumab in Adult Participants With Relapsing Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: natalizumab IV|DRUG: natalizumab SC|DRUG: IV Placebo|DRUG: SC Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peer Navigator Education in Improving Survivorship Care in African American Breast Cancer Survivors
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: educational intervention|OTHER: questionnaire administration|OTHER: counseling intervention|OTHER: survey administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study for the Management of Pediatric Chronic Rhinosinusitis With or Without Balloon Sinuplasty
Status: COMPLETED
Conditions: Rhinitis + Sinusitis, Pediatric Chronic Rhinosinusitis
Interventions: DEVICE: Acclarent Relieva Balloon Sinuplasty|PROCEDURE: Adenoidectomy + Maxillary Sinus Irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short Transverse Versus Conventional Hockey Stick Incision in Kidney Transplantation
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: Short Transverse Incision|PROCEDURE: Hockey Stick Incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficiency of Cervical Ripening BALLoon (Cook) to the DINOprostone (Propess) for the Cervical Maturation in Case of Unfavorable Cervix (Bishop <6) in the Population of Obese Pregnant Women (BMI >= 30 kg/m²)
Status: TERMINATED
Conditions: Delivery
Interventions: DEVICE: Cervical ripening balloon|DRUG: Dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products.
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Experimental Nicotine Replacement Therapy (NRT) 2 mg|DRUG: Experimental Nicotine Replacement Therapy (NRT)|DRUG: Marketed Nicotine Lozenge|DRUG: Marketed Nicotine Lozenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pertussis Acellular Vaccine Adjuvanted With TQL1055
Status: TERMINATED
Conditions: Pertussis
Interventions: OTHER: TQL1055|BIOLOGICAL: Acellular pertussis vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Dextromethorphan and Quinidine in the Treatment of the Pain of Diabetic Neuropathy
Status: COMPLETED
Conditions: Pain|Diabetic Neuropathy
Interventions: DRUG: Neurodex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT)
Status: WITHDRAWN
Conditions: Cardiac Arrest, Out-Of-Hospital|Ventricular Fibrillation|Ventricular Tachycardia
Interventions: DEVICE: Resuscitative Endovascular balloon occlusion of the aorta using a REBOA catheter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCH708980 With and Without AmBisome for Visceral Leishmaniasis
Status: WITHDRAWN
Conditions: Leishmaniasis|Effects of Immunotherapy
Interventions: DRUG: SCH708980 Anti-IL-10 monoclonal|DRUG: AmBisome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of Dopaminergic Medications on Dopamine Transporter Imaging in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Parkinsonian Syndrome
Interventions: DRUG: levodopa|DRUG: Mirapex (pramipexole)|PROCEDURE: [123I]ß-CIT and SPECT imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physiologic Comparison Between NIV-NAVA and PS in Preterm Infants
Status: COMPLETED
Conditions: Noninvasive Neurally Adjusted Ventilatory Assist and Pressure Support in Preterm Infants
Interventions: DEVICE: noninvasive respiratory support with NAVA mode and PSV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Copeptin in Adolescent Participants With Type 1 Diabetes and Early Renal Hemodynamic Function
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Nephropathy|Diabetic Nephropathies|Juvenile Diabetes|Diabetes Mellitus Complication|Autoimmune Diabetes|Type 1 Diabetes Mellitus
Interventions: DRUG: Aminohippurate Sodium Inj 20%|DRUG: Iohexol Inj 300 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Tazarotene Foam|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Video-ludic Re-education of the Paretic Upper Limb in Chronic Hemipartic Patients Post Cerebral Vascular Accident
Status: COMPLETED
Conditions: Stroke|Motor Activity
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Isolating & Exploiting the Mechanisms That Link Breakfast to Human Health - Acute
Status: COMPLETED
Conditions: Postprandial Metabolism|Appetite
Interventions: OTHER: Carbohydrate rich breakfast|DIETARY_SUPPLEMENT: Whey protein enriched breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: VNS During Rehabilitation for Improved Upper Limb Motor Function After Stroke
Status: COMPLETED
Conditions: Stroke|Upper Limb Deficits
Interventions: DEVICE: Vagus Nerve Stimulation (VNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BioACL Reconstruction With Amnion Collagen Matrix Wrap and Stem Cells Case Series
Status: COMPLETED
Conditions: ACL - Anterior Cruciate Ligament Rupture
Interventions: PROCEDURE: Bio-ACL|DEVICE: amnion wrap and BMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietetic and Hygiene Measures in Metabolic Neuropathies: the Neurodiet Study
Status: COMPLETED
Conditions: Peripheral Nervous System Diseases|Diabetic Polyneuropathy|Metabolic Syndrome X
Interventions: BEHAVIORAL: hygienic-dietetic measures|BEHAVIORAL: hygienic-dietetic measures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acetyl-L-Carnitine Hydrochloride in Preventing Peripheral Neuropathy in Patients With Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer Undergoing Chemotherapy
Status: WITHDRAWN
Conditions: Fatigue|Malignant Ovarian Mixed Epithelial Tumor|Neuropathy|Neurotoxicity Syndrome|Ovarian Brenner Tumor|Ovarian Clear Cell Cystadenocarcinoma|Ovarian Endometrioid Adenocarcinoma|Ovarian Mucinous Cystadenocarcinoma|Ovarian Serous Cystadenocarcinoma|Pain|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: DIETARY_SUPPLEMENT: Acetyl-L-Carnitine Hydrochloride|OTHER: Placebo|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Clinical and Biological Prognostic Factors in Patients With Ovarian Cancer Receiving Carboplatin +Paclitaxel With Bevacizumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
Status: COMPLETED
Conditions: Wound Healing
Interventions: DEVICE: GSUC|DEVICE: VAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft Recipients
Status: COMPLETED
Conditions: Graft Rejection|Kidney Failure|Kidney Transplantation
Interventions: DRUG: tacrolimus|DRUG: mycophenolate mofetil|DRUG: methylprednisolone|DRUG: prednisolone|DRUG: sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Study of Dapsone-Adapalene Fixed Combination Gel in Acne
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: DRUG: Fixed Combination dapsone/adapalene Formulation A Gel|DRUG: Fixed Combination dapsone/adapalene Formulation B Gel|DRUG: dapsone 5% gel|DRUG: adapalene 0.3% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Tucatinib With Chemotherapy and Trastuzumab in Advanced Her-2-neu Overexpressing, Previously Treated Breast Cancer.
Status: WITHDRAWN
Conditions: Breast Cancer Stage IV
Interventions: DRUG: Tucatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antineoplaston Therapy in Treating Patients With Stage IV Kidney Cancer
Status: TERMINATED
Conditions: Stage IV Kidney Cancer
Interventions: DRUG: Antineoplaston therapy (Atengenal + Astugenal)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Epidural Patch Versus Pain Block in the Midface for Headache
Status: TERMINATED
Conditions: Postdural Puncture Headache
Interventions: DEVICE: Epidural Blood Patch|DRUG: Sphenopalatine Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Escitalopram in Total Knee Arthroplasty (TKA)
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Escitalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music Played and Acupressure Application on Pain and Anxiety in Women Undergoing Gynecological Examination
Status: COMPLETED
Conditions: Pain, Acute|Anxiety Acute
Interventions: OTHER: acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Pomalidomide in Combination With Low-dose Dexamethasone in Chinese Patients With Relapsed and Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Rehabilitation After Total Knee Arthroplasty Work? - Feasibility Trial
Status: RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: OTHER: Usual care - Municipal exercise-based rehabilitation|OTHER: Return to Everyday life|BEHAVIORAL: Symptom guide and encouragement to follow DHA/WHO recommendations for physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase II Study of the Effects of rhPDGF-BB Injection on Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: DRUG: rhPDGF-BB Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TA-8995 After Multiple Doses in Healthy Subjects
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: TA-8995|DRUG: TA-8995|DRUG: TA-8995|DRUG: TA-8995|DRUG: TA-8995|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Brief Lifestyle Intervention in Type 2 Diabetes, Compared With a Longer Group Educational Program
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Brief lifestyle program|BEHAVIORAL: Conventional lifestyle program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Healing After Deployment of Titanium-nitride-oxide-coated OPTIMAX™ Stent and PROMUS-ELEMENT™ Everolimus-Eluting Stent
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: PROCEDURE: Stenting using Optimax™|PROCEDURE: Stenting using PROMUS Element™ Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Dose Study of the CAM-3001 in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CAM-3001|DRUG: CAM-3001|DRUG: CAM-3001|DRUG: CAM-3001|DRUG: CAM-3001|DRUG: CAM-3001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: metformin|DRUG: glybenclamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of Radotinib Versus Imatinib in Phase III Study for Efficacy With Chinese Patients (RERISE China)
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase
Interventions: DRUG: Radotinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Macular Edema
Interventions: DRUG: Experimental: Group 1|DRUG: Experimental: Group 2|DRUG: Experimental: Group 3|OTHER: Placebo: Group 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dilute Bleach Baths in Pediatric Patients With Atopic Dermatitis
Status: TERMINATED
Conditions: Moderate to Severe Atopic Dermatitis
Interventions: OTHER: Dilute bleach baths|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Phospholipids on Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DIETARY_SUPPLEMENT: milk phospholipid|DIETARY_SUPPLEMENT: diary product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074)
Status: COMPLETED
Conditions: Candidiasis, Esophageal|Candidiasis, Invasive|Aspergillosis
Interventions: DRUG: Caspofungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Myocardial Scars on CMR After COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19|Virus Disease
Interventions: DEVICE: Contrast-enhanced CMR|DIAGNOSTIC_TEST: Exercise test ECG|BIOLOGICAL: Blood sample|DIAGNOSTIC_TEST: Resting 12 lead ECG|DIAGNOSTIC_TEST: 24 hour Holter ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Military Continuity Project
Status: COMPLETED
Conditions: Suicidal Ideation Active|Suicidal and Self-injurious Behavior
Interventions: BEHAVIORAL: TAU|BEHAVIORAL: CCVT+TAU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functionally-tailored Oral Care Intervention for Community-dwelling Older Adults With Dementia and Their Caregivers
Status: COMPLETED
Conditions: Dementia|Cognitive Impairment
Interventions: BEHAVIORAL: Functionally Tailored Oral Care Intervention|BEHAVIORAL: Control Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Vortioxetine (Lu AA21004) in Treating Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-response Relationship of Phototherapy for Hyperbilirubinaemia Using Diodes: is There a "Saturation Point"
Status: COMPLETED
Conditions: Neonatal Hyperbilirubinemia
Interventions: OTHER: Phototherapy with blue light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Trial to Assess the Efficacy and Safety of GO2KA1(Chitosan Oligosaccharide)on Blood Glucose Control
Status: COMPLETED
Conditions: Impaired Fasting Glucose, Newly-diagnosed Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: GO2KA1|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nab-paclitaxel Combined With S-1 Treating Diffuse Type of Stage Ⅲ Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Nab-paclitaxel combined with S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Impact of theERAS Consensus on Patients With Endoscopic Pituitary Tumor Surgery
Status: RECRUITING
Conditions: Enhanced Recovery After Surgery|Pituitary Tumor|Postoperative Complications
Interventions: DIAGNOSTIC_TEST: Malnutrition Universal Screening Tool|DEVICE: TIB Olfactory Test Device|DIAGNOSTIC_TEST: Apfel Score for Postoperative nausea and vomiting|DIAGNOSTIC_TEST: The American Society of Anesthesiologists (ASA) Physical Status Classification|BEHAVIORAL: Short Form-36|BEHAVIORAL: World Health Organization Quality of Life questionnaire (WHOQOL-BREF)|BEHAVIORAL: BDI-II(Beck Depression Inventory-II)|BEHAVIORAL: ERAS Patient Satisfaction Questionnaire(ERAS-PSQ)|BEHAVIORAL: Quality of Recovery-40(QoR-40)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Place of Nasogastric Tube in Uncomplicated Adhesive Small Bowel Obstruction
Status: RECRUITING
Conditions: Small Bowel Obstruction Adhesion
Interventions: PROCEDURE: nasogastric tube|OTHER: NOM without NGT insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Post Facilitation Stretch Versus Active Isolated Stretching Along With Deep Friction Massage in Wallet Sciatica.
Status: UNKNOWN
Conditions: Wallet Sciatica
Interventions: OTHER: Post Facilitation stretch|OTHER: Active Isolated Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts
Status: NOT_YET_RECRUITING
Conditions: Suicide|Suicide, Attempted|Suicidal Ideation
Interventions: BEHAVIORAL: Enhanced Outreach Intervention (EOI) plus Care as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Chinese|Homologous Recombination Deficiency|BRCA1 Mutation|BRCA2 Mutation|Prognosis|Homologous Recombination Genes
Interventions: GENETIC: Evaluation of homologous recombination deficiency score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Zinc Supplementation in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DIETARY_SUPPLEMENT: Zinc gluconate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of PEGPH20 in Combination With Avelumab in Chemotherapy Resistant Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer
Interventions: DRUG: PEGylated Recombinant Human Hyaluronidase (PEGPH20)|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlled Human Infection Model Challenge/Rechallenge
Status: COMPLETED
Conditions: Shigellosis
Interventions: BIOLOGICAL: S. sonnei 53G|BIOLOGICAL: S. flexneri 2a 2457T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Capecitabine, Oxaliplatin & Bevacizumab for Metastatic / Unresectable Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Capecitabine|DRUG: Oxaliplatin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trauma Informed Prevention for Substance Use and Risky Sex
Status: COMPLETED
Conditions: Substance Use|HIV/AIDS
Interventions: BEHAVIORAL: TIPS app|BEHAVIORAL: Trauma Focused-Cognitive Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 3 Days Amoxicillin Versus Placebo for Fast Breathing Childhood Pneumonia in Malawi
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Amoxicillin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Epinephrine, Dexamethasone, and Hypertonic Saline in Bronchiolitis, Randomised Clinical Trial of Efficacy and Safety
Status: COMPLETED
Conditions: Bronchiolitis
Interventions: DRUG: Epinephrine and Dexamethasone|DRUG: Hypertonic Saline|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Inactive HBsAg Carriers (IHCs) Treated With Pegylated Interferon α2b Based Intervention Therapy
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: PegIFN α- 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Visceral Manipulation Versus Integrated Neuromuscular Inhibition Technique in Shoulder Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Shoulder Impingement
Interventions: OTHER: visceral manipulation|OTHER: integrated neuromuscular inhibition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DIAGNOSTIC_TEST: High resolution MRI scan|DIAGNOSTIC_TEST: mrTRG assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of Adjuvant Chemotherapy in Patients With Locally Advanced Cervical Cancer Who Did Not Meet the NCCN Guidelines for Adjuvant Treatment After NACT Combined With Surgery
Status: RECRUITING
Conditions: Uterine Cervical Neoplasms|Cervical Cancer
Interventions: DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of GlucoNorm vs Glyburide on Post-Prandial Hyperglycemia in Elderly Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: glyburide|DRUG: GlucoNorm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HeartLight: Heart Rate Monitoring for Newborn Resuscitation
Status: COMPLETED
Conditions: Infant, Newborn, Diseases|Fetus or Neonate Affected by Cesarean Section|Infant, Premature, Diseases
Interventions: DEVICE: HeartLight hat|DEVICE: The HeartLight hat with in-built sensor|DEVICE: HeartLight|DEVICE: HeartLight device|OTHER: parental feedback|OTHER: healthcare provider feedback
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Isometric Handgrip Training on Blood Pressure of Peripheral Artery Disease Patients
Status: COMPLETED
Conditions: Peripheral Artery Disease
Interventions: OTHER: Isometric Handgrip Training Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Muscle Energy Technique and Routine Physical Therapy on Quadratus Lumborum in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Routine Physical Therapy|OTHER: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Impairment, Cholestatic Liver Disease, & NASH With Advanced Fibrosis & Normal Hepatic Function
Status: RECRUITING
Conditions: Hepatic Impairment
Interventions: DRUG: Saroglitazar Magnesium 2 mg|DRUG: Saroglitazar Magnesium 4 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee|Sarcopenia
Interventions: OTHER: Knee strengthening exercises with isokinetic dynamometer|OTHER: Strengthening around the knees with home exercise programe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection
Status: NOT_YET_RECRUITING
Conditions: Mycobacterium; Xenopi|Lung Diseases
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Dalotuzumab (MK-0646) in Combination With Erlotinib for Participants With Non-Small Cell Lung Cancer (MK-0646-007)
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: Dalotuzumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DEVICE: AnapnoGuard 100,|DEVICE: routine mechanical ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercise on Clinical Symptoms, Cognitive Performance, and Quality of Life in Schizophrenia Patients Treated With Clozapine
Status: RECRUITING
Conditions: Schizophrenia|Clozapine|Exercise
Interventions: OTHER: physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Modulating Cerebellar Activity With Low-intensity Focused Ultrasound Stimulation for Primary Orthostatic Tremor
Status: RECRUITING
Conditions: Orthostatic Tremor
Interventions: DEVICE: LIFUS Online Real|DEVICE: LIFUS Online Sham|DEVICE: LIFUS Offline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Busulfan, Cyclophosphamide, and Autologous Stem Cell Transplant in Treating Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: busulfan|DRUG: cyclophosphamide|PROCEDURE: autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRE Scan for the Assessment of Differences in Tissue Stiffness Between Radiation Necrosis and Recurrent Glioma in Patients With Previously Treated Gliomas
Status: RECRUITING
Conditions: Glioma
Interventions: PROCEDURE: Magnetic Resonance Elastography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Self-help Forest Bathing (Shinrin-yoku) on Depression, Anxiety, and Stress
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety|Stress
Interventions: BEHAVIORAL: Self-help Forest Bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LLIF Plus Posterior Decompression for Severe Lumbar Spinal Stenosis
Status: COMPLETED
Conditions: Lumbar Spine Degeneration|Lumbar Spinal Stenosis
Interventions: PROCEDURE: Lateral lumbar interbody fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Investigating the Comparison of Three Different Concentrations of NN9535 in Healthy Male Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: semaglutide|DRUG: semaglutide|DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Blood Levels of Nicotine Following an Electronic Cigarette
Status: COMPLETED
Conditions: Nicotine Replacement Therapy
Interventions: DEVICE: CN electronic cigarette 10 mg|DEVICE: CN electronic cigarette 15 mg|DEVICE: Nicorette Inhalator 15 mg|OTHER: Cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 17OHP for Reduction of Neonatal Morbidity Due to Preterm Birth (PTB) in Twin and Triplet Pregnancies
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: 17-alpha-hydroxyprogesterone caproate injectable|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve Thrombosis
Status: COMPLETED
Conditions: Prosthetic Valve Thrombosis
Interventions: DRUG: Streptokinase|DRUG: Streptokinase|DRUG: Tissue plasminogen activator|DRUG: Tissue Plasminogen Activator|DRUG: Tissue Plasminogen Activator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micro-Ultrasound for the Detection and Localization of Prostate Cancer Tumors in Patients Undergoing Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: DEVICE: Digital Image Analysis|PROCEDURE: Radical Prostatectomy|PROCEDURE: Transrectal Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Topical Minocycline in Managing Symptomatic Oral Lichen Planus
Status: UNKNOWN
Conditions: Oral Lichen Planus
Interventions: DRUG: Minocycline|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subject Satisfaction With BOTOX® Cosmetic Treatment in Facial Rhytides
Status: COMPLETED
Conditions: Facial Rhytides
Interventions: BIOLOGICAL: onabotulinumtoxinA|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT