pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of GSK2126458 and GSK1120212 Combination Therapy in Subjects With Advanced Solid Tumors.
Status: TERMINATED
Conditions: Cancer
Interventions: DRUG: GSK2126458 and GSK1120212
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of NovoPen® 4 on Treatment Satisfaction of Insulin Therapy in Type 1 or Type 2 Subjects With Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoPen® 4
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Molecular Basis of Loss Aversion
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: single-dose madopar, single-dose propranolol, and single-dose placebo by order|DRUG: single-dose madopar, single-dose placebo, and single-dose propranolol by order|DRUG: single-dose propranolol, single-dose madopar, and single-dose placebo by order|DRUG: single-dose propranolol, single-dose placebo, and single-dose madopar by order|DRUG: single-dose placebo, single-dose propranolol, and single-dose madopar by order|DRUG: single-dose placebo, single-dose madopar, and single-dose propranolol by order
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Home Transcranial Direct-Current Stimulation for Motoric Cognitive Risk Syndrome
Status: NOT_YET_RECRUITING
Conditions: Motoric Cognitive Risk Syndrome
Interventions: DRUG: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Mood Effects of Serotonin Agonists
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lysergic Acid Diethylamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Everolimus and LongActing Octreotide Trial in Polycystic Livers
Status: COMPLETED
Conditions: Polycystic Liver Disease
Interventions: DRUG: Everolimus|DRUG: Octreotide LAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholecalciferol on Depressive Symptoms in Type 2 Diabetes Mellitus Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2|Depressive Symptoms
Interventions: DRUG: Cholecalciferol 4000 IU Oral Capsule, Liquid Filled|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Osteopathic Manipulative Therapy in Paediatric Patients, With High Frequency Headache.
Status: UNKNOWN
Conditions: Headache Disorders|Primary Headache Disorder
Interventions: OTHER: Osteopathic manipulative therapy (OMTh)|OTHER: Light Touch Therapy (LTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of the Novel Intra- Semispinal Fascial Plane Block in Posterior Cervical Spine Surgery
Status: COMPLETED
Conditions: Cervical Spine Surgery
Interventions: PROCEDURE: Inter-semispinal plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effectiveness and Quality of Life With the Administration of the Fixed Combination of Budesonide Formoterol in Greek Patients With Asthma During Routine Clinical Practice.
Status: COMPLETED
Conditions: Asthma|Quality of Life
Interventions: OTHER: Budesonide/Formoterol treated patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extraesophageal Reflux - Feasibility of Measurement of Pepsin in Saliva as a Diagnostic Option
Status: COMPLETED
Conditions: Extraesophageal Reflux
Interventions: DIAGNOSTIC_TEST: Pepsin in saliva test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Policosanol to Improve Platelet Reactivity After Percutaneous Coronary Stent Implantation (PCI)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: high maintenance clopidogrel|DRUG: routine dual antiplatelet|DRUG: policosanol plus dual antiplatelet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Cancer|Metastatic Colorectal Cancer
Interventions: DRUG: MRTX849|BIOLOGICAL: Cetuximab|DRUG: mFOLFOX6 Regimen|DRUG: FOLFIRI Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Network Intervention to Engage Community PLH to Engage in HIV Medical Care
Status: COMPLETED
Conditions: Human Immunodeficiency Virus|HIV/AIDS
Interventions: BEHAVIORAL: Social Network Training|BEHAVIORAL: Single Care-Related Counseling Session and Referral to Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pravastatin Sodium 80 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pravastatin sodium 80 mg tablets|DRUG: Pravachol® 80 mg tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Agreement and Accuracy of Different Devices for Biometry Measurements in Patients With Cataract
Status: UNKNOWN
Conditions: Cataract|Cornea|Surgery
Interventions: DIAGNOSTIC_TEST: Biometry|DIAGNOSTIC_TEST: Keratometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial of EVL\GVS Alone vs. EVL\GVS Combined Propranolol (S-HCC)
Status: UNKNOWN
Conditions: Gastroesophageal Varices Hemorrhage|Hepatocellular Carcinoma
Interventions: DRUG: propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilatory Responses to Hypercapnic and Hypoxic Conditions in Hyperventilants
Status: COMPLETED
Conditions: Hyperventilation Syndrome|Hypercapnia|Hypoxia
Interventions: DIAGNOSTIC_TEST: Hypercapnic hyperoxic ventilatory response|DIAGNOSTIC_TEST: Hypoxic eucapnic ventilatory response
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Novel Vitality Indices Derived From the Hexoskin in Patients Affected With Angina Undergoing Coronary Revascularization or Medical Therapy
Status: COMPLETED
Conditions: Chronic Stable Angina
Interventions: DEVICE: Hexoskin Vest|BEHAVIORAL: Cardiac rehabilitation program|OTHER: Anxiety assessment as determined by the GAD-7|OTHER: Angina assessment with the angina diary, the SAQ and the SF-36|OTHER: Exercise stress test|OTHER: Holter monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Functional Gastrointestinal Disorders|Irritable Bowel Syndrome|Functional Abdominal Pain Syndrome
Interventions: OTHER: Home-based hypnotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elmo Respiratory Support Project - COVID-19
Status: COMPLETED
Conditions: COVID-19|Respiratory Failure With Hypoxia
Interventions: OTHER: ELMO PROJECT AT COVID-19: STUDY IN HUMANS|DEVICE: ELMO PROJECT AT COVID-19: PROOF OF CONCEPT AND USABILITY
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Clinical Trial Evaluating the Efficiency of Holmium Laser Settings on Urinary Stones
Status: COMPLETED
Conditions: Stone Ureter|Stone;Renal|Surgery
Interventions: DEVICE: Holmium:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metal Versus Plastic Stent in Malignant Hilar Biliary Obstruction
Status: UNKNOWN
Conditions: Malignant Hepatobiliary Neoplasm
Interventions: PROCEDURE: endoscopic retrograde cholangio-pancreatography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel
Status: COMPLETED
Conditions: Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel|Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel
Interventions: DRUG: Clopidogrel+Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facial Emotion Recognition in Insomnia and Emotional Regulation
Status: NOT_YET_RECRUITING
Conditions: Chronic Insomnia
Interventions: DIAGNOSTIC_TEST: Facial emotion recognition test with and without eye-tracking and Cognitive Emotion Regulation. Questionnaire (CERQ)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influenza Vaccine Challenge Study in Healthy Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza vaccine (FLU-v)|BIOLOGICAL: Placebo (adjuvant only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Short-Term Statins and NSAIDs on Levels of Beta-Amyloid, a Protein Associated With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Lovostatin|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Supplementation on Endothelial Function II
Status: RECRUITING
Conditions: Cardiovascular Disease|Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Goodbelly first|DIETARY_SUPPLEMENT: Placebo first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Deeper Intubation Make Effects on Cervical Esophageal ESD
Status: RECRUITING
Conditions: Carcinoma in Situ of Cervical Part of Esophagus
Interventions: PROCEDURE: Deeper endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Ningetinib in Advanced NSCLC Skipping Mutations With MET Exon 14 Skipping Mutations
Status: NOT_YET_RECRUITING
Conditions: Advanced NSCLC
Interventions: DRUG: CT053PTSA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Naltrexone SR/ Bupropion SR in Overweight or Obese Subjects With Major Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: naltrexone SR 32 mg/ bupropion SR 360 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy
Status: COMPLETED
Conditions: Myasthenia Gravis
Interventions: PROCEDURE: thymectomy plus prednisone|DRUG: prednisone alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cyclosporine in Post-LASIK Patients
Status: COMPLETED
Conditions: Laser In Situ Keratomileusis
Interventions: DRUG: Cyclosporine 0.010% eye drops|DRUG: Cyclosporine 0.005% eye drops|DRUG: Placebo (Vehicle for Cyclosporine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness of Two Painkillers for Treating Pain After Limb Injuries
Status: COMPLETED
Conditions: Soft Tissue Injuries
Interventions: DRUG: Paracetamol|DRUG: Ibuprofen|DRUG: Paracetamol Placebo|DRUG: Ibuprofen placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Biological Activity of Intraperitoneal (IP) EGEN-001 Administered Alone and in Combination With Standard Chemotherapy in Colorectal Peritoneal Carcinomatosis Patients
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: EGEN-001-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: DRUG: Mupirocin calcium|DRUG: Mupirocin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: PREVENTION
Clinical trial: Atezolizumab Monotherapy vs Atezolizumab Plus Cobimetinib in Liver Metastases From Colorectal Cancer
Status: WITHDRAWN
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Atezolizumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Drug-drug Interactions Between DWC202313 and DWC202314 in Healthy Subjects
Status: RECRUITING
Conditions: Drug Drug Interaction
Interventions: DRUG: DWC202313|DRUG: DWC202314
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Fed Healthy Volunteers
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: repaglinide|DRUG: metformin|DRUG: repaglinide and metformin combination tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spurring Innovation to Promote HIV Testing: An RCT Evaluating Crowdsourcing
Status: COMPLETED
Conditions: HIV
Interventions: BEHAVIORAL: Conventional Video|BEHAVIORAL: Crowdsourced Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
Status: COMPLETED
Conditions: Stroke|Acute
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Victoza® Versus Lyxumia® on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: Liraglutide|DRUG: Lixisenatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metoclopramide for Post Traumatic Headache
Status: COMPLETED
Conditions: Post-Traumatic Headache
Interventions: DRUG: Metoclopramide|DRUG: Diphenhydramine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Malnutrition And Sarcopenia In Older Adults With Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Leukemia, Myeloid
Interventions: DEVICE: Bioelectrical Impedence Analysis Device|OTHER: 6 Minute Walk Test|DIAGNOSTIC_TEST: Computed Tomography Scans to Measure Skeletal Muscular Index|DIAGNOSTIC_TEST: Blood Test/Blood Draw|OTHER: Hand Grip Strength Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surufatinib or Surufatinib Combined With Vinorelbine for Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: Surufatinib|DRUG: Surufatinib Plus Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expanding the Infant Achievements Intervention Through Community Partnerships
Status: ENROLLING_BY_INVITATION
Conditions: Child Development|Infant Development|Developmental Delay|Language Development
Interventions: BEHAVIORAL: Building Capacity for Infant Achievements in Child Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer
Status: TERMINATED
Conditions: Barrett Esophagus|Esophageal Neoplasms|Deglutition Disorders|GERD|Neoplasm
Interventions: DEVICE: CSA System (CryoSpray AblationTM System)|DEVICE: CryoSpray Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tolerance of a Probiotic Formula
Status: COMPLETED
Conditions: Safety Issues
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Observational Study Evaluating SYMLIN® (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Type 2 Diabetes Mellitus
Interventions: DRUG: pramlintide acetate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of the Utility of an Artificial System for the Large-scale Screening of Scoliosis
Status: COMPLETED
Conditions: Orthopedic Disorder of Spine|Artificial Intelligence|Scoliosis
Interventions: DEVICE: An artificial system for the screening of scoliosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Lymphadenectomy and Chemotherapy TIP on Inguinal Lymph Nodes in Squamous Cell Carcinoma of the Penis
Status: RECRUITING
Conditions: Penile Cancer|Squamous Carcinoma
Interventions: DRUG: Chemotherapy TIP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Incidence and Risks Factors of CMV Reactivation in Patients Receiving of CAR-T Cells for Acute Leukemia and Lymphoma Relapse, a Cohort Study Analysis
Status: RECRUITING
Conditions: Cytomegalovirus Infections|Acute Leukemia|B Cell Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II Study of 131I-rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma (DLBCL)
Status: UNKNOWN
Conditions: Relapsed or Refractory Diffuse Large B Cell Lymphoma
Interventions: DRUG: 131I-rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure
Status: COMPLETED
Conditions: Congestive Heart Failure
Interventions: DEVICE: Cardiac Resynchronization Therapy with & without defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy
Status: TERMINATED
Conditions: Cardiac AL Amyloidosis
Interventions: DRUG: Doxycycline|DRUG: Standard of care therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Web-supported Interactive Nurse Program in Fibromyalgia Patients: A Mixed Method Study
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Web-assisted patient education intervention designed according to the common-sense model|BEHAVIORAL: The website where the Turkish Physical Medicine and Rehabilitation Association Fibromyalgia patient booklet is available as pdf.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Dosing of 1st Line Antituberculosis and Antiretroviral Drugs in Children (a Pharmacokinetic Study)
Status: COMPLETED
Conditions: Tuberculosis|HIV
Interventions: DRUG: 8 hourly LPV/r during TB treatment|DRUG: Nevirapine|DRUG: Lopinavir/Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Therapeutic Use of Botulinum Toxin Type A in Subacute Cervical/Upper Back Pain
Status: COMPLETED
Conditions: Subacute Cervical Pain|Subacute Upper Back Pain
Interventions: DRUG: Botulinum Toxin type a (Botox)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate
Interventions: DRUG: Atrasentan|DRUG: Zoledronic Acid (Zometa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for Methamphetamine Use Disorder
Status: RECRUITING
Conditions: Methamphetamine Use Disorder
Interventions: DEVICE: Experimental 1 - DBS of bilateral NAc - 6 months of active stimulation -- > 6 months of sham stimulation|DEVICE: Experimental 2 - DBS of bilateral NAc - 6 months of sham stimulation -- > 6 months of active stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal Hypertension
Status: COMPLETED
Conditions: Acute Pancreatitis|Intra-abdominal Hypertension
Interventions: DRUG: Neostigmine Methylsulfate 1 MG/ML|COMBINATION_PRODUCT: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: VIrtual REality Glasses for the Enhancement of Acute BRACHYtherapy Tolerance for Endometrial Cancer Patients.
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: DEVICE: Virtual reality Helmet|OTHER: No Virtual Reality Helmet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff
Status: COMPLETED
Conditions: Seasonal Affective Disorder|Vitamin D3|Mental Health|Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Age and Fitness on Vascular Function and Oxidative Stress During Acute Inflammation
Status: TERMINATED
Conditions: Aging|Inflammation
Interventions: BIOLOGICAL: Typhoid Vaccine|DIETARY_SUPPLEMENT: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: BH4 5mg|DRUG: BH4 20mg|DIETARY_SUPPLEMENT: Antioxidant Cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Status: NOT_YET_RECRUITING
Conditions: Myopia
Interventions: DEVICE: Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2D 4K vs. 3D HD in Bariatric Laparoscopic Surgery
Status: RECRUITING
Conditions: Laparoscopy
Interventions: DEVICE: Gastric bypass surgery with 2D 4K laparoscopic imaging|DEVICE: Gastric bypass surgery with 3D HD laparoscopic imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Efficacy and Safety Study of CD07805/47 Topical Gel in Subjects With Facial Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: CD07805/47 gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Practical RCT of TCM in the Treatment of LCOVID and Analysis of Syndrome Types and Medication Characteristics.
Status: NOT_YET_RECRUITING
Conditions: Long COVID
Interventions: DRUG: Traditional Chinese medicine treatment|DRUG: Western medicine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effective Caregiving for Neonatal Abstinence Syndrome: Testing an Instructional Mobile Technology Platform for High-Risk Pregnant Women
Status: RECRUITING
Conditions: Neonatal Abstinence Syndrome|Opioid-use Disorder
Interventions: BEHAVIORAL: Mobile-based NAS Caregiving Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution: A Pilot Study
Status: COMPLETED
Conditions: Catheter Related Infection|Bacteremia
Interventions: OTHER: 30 % ethanol / 4% sodium citrate catheter locking solution|DRUG: Heparin 1000 u / ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Recombine Endostatin With Neoadjuvant Chemotherapy Followed by Concurrent Chemoradiation in Advanced Nasopharynx Cancer
Status: UNKNOWN
Conditions: 1、Enough Cases|2、Elekta Precise 1343 Digital Control Electron Linear Accelerator|Can Undertake Nasopharyngeal Carcinoma Specimens in the Materia，|Image Department of Nose Pharynx Ministry MRI Dynamic Testing,
Interventions: DRUG: Recombine Endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Extruded the effectıveness of Prone posıtıon ın ınfants evaluatıon
Status: COMPLETED
Conditions: Prone posıtıon
Interventions: OTHER: Prone positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of a Low Protein Diet in Patients With Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Mild Dementia|Fasting-Mimicking Diet
Interventions: DIETARY_SUPPLEMENT: Fasting-Mimicking Diet ProlonADTM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: How Desloratadine (Clarinex, Aerius) Affects Quality of Life in Patients With Chronic Idiopathic Urticaria (Have Had Hives for 6 Weeks or Longer)(Study P02988)
Status: COMPLETED
Conditions: Urticaria
Interventions: DRUG: desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma|Follicular Lymphoma|Marginal Zone Lymphoma|Small Lymphocytic Lymphoma|Mantle Cell Lymphoma|Chronic Lymphocytic Leukemia|High-grade B-cell Lymphoma|Primary Mediastinal Large B-cell Lymphoma
Interventions: BIOLOGICAL: GEN3009|BIOLOGICAL: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Testosterone Undecanoate to Improve Sexual Function in Postmenopausal Women
Status: COMPLETED
Conditions: Female Sexual Dysfunction
Interventions: DRUG: Testosterone undecanoate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DEVICE: HeartWare® VAS (HVAD)|DEVICE: Control LVAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of and Exploring the Processes of Free Movement Dance as a Physical Therapy Intervention for Female Patients Diagnosed With Chronic Widespread Pain (Including Fibromyalgia).
Status: RECRUITING
Conditions: Fibromyalgia|Chronic Widespread Pain
Interventions: OTHER: Free Movement Dance|OTHER: Modified person-centred progressive resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measuring and Reducing Excessive Infant Crying
Status: COMPLETED
Conditions: Infant Colic|Postpartum Depression
Interventions: BEHAVIORAL: The Happiest Baby on The Block|BEHAVIORAL: AAP Infant Colic counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Stereotactic Body Radiation Therapy and FOLFIRINOX in the Neoadjuvant Therapy of Pancreatic Cancer
Status: COMPLETED
Conditions: Cancer of Pancreas|Cancer of the Pancreas|Neoplasms, Pancreatic|Pancreas Cancer|Pancreas Neoplasms
Interventions: DRUG: Modified FOLFIRINOX|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: STEMVAC in Patients With Early Stage Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: BIOLOGICAL: CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: (H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) Cholesterol
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DEVICE: Secura then Futura|DEVICE: Futura then Secura
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Safety and the Ability of a DNA Vaccine to Protect Against Dengue Disease
Status: COMPLETED
Conditions: Dengue Disease|Dengue Fever
Interventions: BIOLOGICAL: Tetravalent Dengue Vaccine (TVDV)|BIOLOGICAL: Tetravalent Dengue Vaccine (TVDV) with Vaxfectin® (low-dose)|BIOLOGICAL: Tetravalent Dengue Vaccine TVDV with Vaxfectin® (High Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Immunogenicity of INO-4800 for COVID19 in Healthy Volunteers
Status: WITHDRAWN
Conditions: Coronavirus Infection
Interventions: DRUG: INO-4800|DRUG: INO-9112|DEVICE: CELLECTRA® 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of ICS/LABA vs. LAMA/LABA in Patients With Different COPD Phenotypes.
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Fluticasone Furoate/Vilanterol 100/25 mcgs|DRUG: Umeclidinium/Vilanterol 62.5/25 mcgs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effects of Oxygen-ozone Therapy on Back Pain in Subjects Aged 65 or Older
Status: UNKNOWN
Conditions: Back Pain
Interventions: DRUG: Intramuscular/paravertebral injections of Oxygen-Ozone|OTHER: Simulated intramuscular/paravertebral injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Restoration of Standing and Walking With ISMS in Humans
Status: WITHDRAWN
Conditions: Spinal Cord Injury|Paralysis
Interventions: OTHER: Movement Assessment|OTHER: MRI Scan|PROCEDURE: IntraSpinal Micro-Stimulation|OTHER: Follow up clinical exam|OTHER: Post Op MRI Scan|OTHER: Follow up gait assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in Lesotho
Status: RECRUITING
Conditions: Health Behavior|Motivation|Health Care Utilization|Consumer Behavior|Social Behavior|Health Care Seeking Behavior|Recruitment|Researcher-Subject Relations
Interventions: BEHAVIORAL: Partner support|BEHAVIORAL: Formal recruiter attire|BEHAVIORAL: Without Partner support|BEHAVIORAL: Casual recruiter attire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open Versus Robotic Retromuscular Ventral Hernia Repair
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventral Hernia
Interventions: PROCEDURE: open ventral hernia repair|PROCEDURE: robotic ventral hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Carvedilol on Suppressing the Premature Ventricular Complex/Ventricular Tachycardia From Outflow Tract
Status: UNKNOWN
Conditions: Ventricular Premature Complexes|Outflow Tract|Carvedilol
Interventions: DRUG: Carvedilol|DRUG: Flecainide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lidocaine and Remifentanil for the Effect on Responses to the Endotracheal Tube During Emergence From General Anesthesia
Status: COMPLETED
Conditions: Thyroidectomy
Interventions: DRUG: remifentanil / lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of the SNaP Wound Care System
Status: WITHDRAWN
Conditions: Acute and Chronic Wounds|Pressure Ulcers|Trauma Wounds|Diabetic Foot Ulcers|Venous Stasis Ulcers
Interventions: DEVICE: SNaP Wound Care System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Immunomodulatory Effect of Eprolidone on Patients With Chronic Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Chronic Heart Failure Patients
Interventions: DRUG: Eprolidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture
Status: TERMINATED
Conditions: Pain, Postoperative|Fractures, Closed|Fractures, Open
Interventions: BEHAVIORAL: Cognitive behavioural therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label, Extension Study of Aripiprazole Intramuscular Depot (OPC-14597, Lu AF41155) in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole IM Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telephone Services for Participation in Colorectal Cancer Screening
Status: UNKNOWN
Conditions: Participation Rate, Patient
Interventions: BEHAVIORAL: Telephone recruitment to screening colonoscopy|BEHAVIORAL: Combined methods recruitment to screening colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cardiac Output and Duplex Sonography in Carotid Endarterectomy
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: PROCEDURE: Regional anesthesia|PROCEDURE: General anesthesia|DEVICE: Transcranial Doppler ultrasonography|PROCEDURE: blood gas analysis|PROCEDURE: invasive arterial blood pressure measurement|PROCEDURE: arterial blood gas measurement|BEHAVIORAL: Neurological Control|BEHAVIORAL: NIRS monitoring|DEVICE: oxygen supply (not invasive 'Vigileo')
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subthreshold Stimulation Versus Suprathreshold Stimulation in People With Chronic Low Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Pain|Trigger Point Pain, Myofascial
Interventions: DEVICE: electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent-supported Social Skills Training for Teens With Autism Spectrum Disorders (PEERS-K)
Status: UNKNOWN
Conditions: Autism Spectrum Disorders
Interventions: BEHAVIORAL: parent-assisted social skills training program for adolescents with autism spectrum disorder|BEHAVIORAL: Delayed intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CENtral Blood Pressure Targeting: A Pragmatic RAndomized Pilot triaL in Advanced Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Hypertension
Interventions: OTHER: Central vs brachial systolic blood pressure targeting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the 'EuPCV15' in Healthy Korean Adults
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: EuPCV15|BIOLOGICAL: Prevenar13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Robotic Versus Conventional Therapy For Post-Stroke Hand Motoric Recovery
Status: NOT_YET_RECRUITING
Conditions: Stroke|Physical Disability|Upper Extremity Paresis
Interventions: PROCEDURE: SYREBO|PROCEDURE: Conventional Mirror Method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Pharmacokinetics of Albiglutide in Normal and Renally Impaired Subjects.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OCT Imaging of Papilledema in Pediatric Idiopathic Intracranial Hypertension
Status: UNKNOWN
Conditions: Pediatric Idiopathic Intracranial Hypertension
Interventions: OTHER: OCT Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Safety of a Novel Milk Protein Peptide
Status: COMPLETED
Conditions: Drug Safety
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed milk protein mixture|DIETARY_SUPPLEMENT: Glycerol placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetics, Safety, and Tolerability of Subcutaneous GAMUNEX-C in Pediatric Subjects With Primary Immunodeficiency
Status: COMPLETED
Conditions: Primary Immunodeficiency
Interventions: BIOLOGICAL: GAMUNEX-C|BIOLOGICAL: GAMUNEX-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: European Study on Three Different Approaches to Managing Class 2 Cavities in Primary Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: PROCEDURE: Hall Technique|PROCEDURE: Non-Restorative Caries Treatment|PROCEDURE: Conventional Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Gastrointestinal Diseases|Healthy
Interventions: PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Theory-driven Visual Arts-based Intervention for Community-dwelling Stroke Survivors
Status: RECRUITING
Conditions: Stroke|Psychosocial Problem
Interventions: OTHER: Visual arts-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal
Status: COMPLETED
Conditions: Tooth Stain
Interventions: DRUG: Colgate® Regular Cavity Protection|DRUG: Experimental Mouth Rinse|OTHER: Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer|Surgery--Complications
Interventions: DIETARY_SUPPLEMENT: MICODIGEST 2.0 supplement|DIETARY_SUPPLEMENT: Placebo supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL)
Status: COMPLETED
Conditions: Prostate Cancer Metastatic
Interventions: DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Vitamin D3 Supplement on Post-Op Outcomes
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Vitamin D|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Sotyktu and Enstilar for Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Enstilar|DRUG: Deucravacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema
Status: TERMINATED
Conditions: Diabetic Macular Edema (DME)
Interventions: DRUG: AXT107 0.1 mg|DRUG: AXT107 0.25 mg|DRUG: AXT107 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MT-101 in Subjects With CD5+ Relapsed/Refractory TCL
Status: SUSPENDED
Conditions: Lymphoma, T-Cell, Peripheral|Lymphoma, T-Cell, Cutaneous|Mycosis Fungoides|Adoptive Cellular Immunotherapy|Cell Therapy
Interventions: BIOLOGICAL: MT-101|OTHER: MT-101 + Conditioning (Lymphodepleting) Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT