pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases
Status: NOT_YET_RECRUITING
Conditions: Acute Graft Versus Host Disease|Malignant Hematologic Neoplasm
Interventions: DRUG: Basiliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Seaweed-derived Rhamnan Sulfate and Vascular Function
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Rhamnan sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: CVisc50 OVD|DEVICE: ProVisc OVD|PROCEDURE: Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of N-acetylcysteine (NAC) on Impulse Control Disorders
Status: UNKNOWN
Conditions: Impulse Control Disorder|Parkinson
Interventions: BIOLOGICAL: Variation of behaviors of Parkinson's disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
Status: RECRUITING
Conditions: TMJ|Apical Periodontitis|Periodontal Inflammation|Retained Tooth|MRI
Interventions: DEVICE: MRI of teeth and surrounding structures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease
Status: RECRUITING
Conditions: Liver Disease Chronic|End Stage Liver DIsease|Cirrhosis|Cirrhosis, Liver|Advanced Cirrhosis
Interventions: BEHAVIORAL: LiverPAL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: "Effectiveness of the Ultrasound - Guided Lengthening of the Gastrocsoleus Complex"
Status: RECRUITING
Conditions: Gastrocnemius Equinus
Interventions: PROCEDURE: Stayer|PROCEDURE: Plantar transection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Estimate The Effect Of Omeprazole On The Pharmacokinetics Of Nelfinavir In Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nelfinavir and Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of PN-235 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PN-235|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease
Status: UNKNOWN
Conditions: Graft vs Host Disease
Interventions: BIOLOGICAL: mesenchymal stem cells|DRUG: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cervical Restorations Placed Under Two Isolation Methods
Status: COMPLETED
Conditions: Non-carious Cervical Lesions
Interventions: PROCEDURE: Relative isolation with cotton rolls|PROCEDURE: Absolute isolation with rubber dam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System
Status: COMPLETED
Conditions: Symptomatic Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Implantation (TAVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Peripheral Cutaneous Nerve Block of Knee Joint After Total Knee Arthroplasty
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Knee|Analgesia
Interventions: PROCEDURE: New local anesthesia injection site and new local anesthetic drug formulation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Pharmacokinetics and Safety of ASC16 Tablets in Healthy Volunteers in China
Status: COMPLETED
Conditions: Chronic Hepatitis c
Interventions: DRUG: Ravidasvir 50mg|DRUG: Ravidasvir 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed Dose Combination, With or Without Ribavirin, in Egyptian Adults With Chronic Genotype 4 HCV Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Encouraging LPG Adoption in Ghana: A Factorial Randomized Clinical Trial to Enhance LPG Adoption & Sustained Use
Status: COMPLETED
Conditions: Behavior, Consumer|Health Knowledge, Attitudes, Practice|Health Attitude
Interventions: BEHAVIORAL: RANAS Behavior Change Intervention|OTHER: Infrastructural Intervention - Direct Delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Single Dose Administration of Ketamine 10, 20, 40 and 80 mg and 5 mg Solution for Infusion in 15 Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: GSK Biologicals' candidate Plasmodium falciparum malaria vaccine 257049|BIOLOGICAL: Rabipur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of the Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Surgery Patients
Status: COMPLETED
Conditions: Anxiety
Interventions: OTHER: Lavandula Angustifolia oil (LO)|OTHER: Michelia Alba Leaf oil (MA)|OTHER: Almond oil (AO)|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Tolerability and Pharmacokinetics of TQB2858 Injection in Subjects With Advanced Malignant Tumors
Status: TERMINATED
Conditions: Advanced Cancer|Advanced Soft-tissue Sarcoma
Interventions: DRUG: TQB2858 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Special Drug Use Observational Study of Xolair in Patients With Severe to Most Severe Seasonal Allergic Rhinitis Aged ≥ 12 Years and < 18 Years Whose Symptoms Were Inadequately Controlled Despite to Conventional Therapies
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Xolair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of the Snackability Smartphone Application to Improve Quality of the Snack Intake, General Diet Quality, and Weight Among College Students
Status: COMPLETED
Conditions: Obesity|Diet, Healthy
Interventions: BEHAVIORAL: Snackability app|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Bi-environmental Conditions During Occupational Related Activity
Status: COMPLETED
Conditions: Hyperthermia|Hypothermia
Interventions: OTHER: Zero Degrees Cold Environment|OTHER: Eight Degrees Cold Environment|OTHER: Ten Degrees Cold Environment|OTHER: 40 degrees Hot Environment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nutrition Optimization and Community Upliftment for Postpartum Recovery
Status: NOT_YET_RECRUITING
Conditions: Obesity, Maternal|Gestational Diabetes
Interventions: BEHAVIORAL: MFeast ENHANCED|BEHAVIORAL: MFeast Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: BEHAVIORAL: NDURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Zn Biofortified Wheat in Improving Zn Status in Indian School Children With Low Zn Status
Status: COMPLETED
Conditions: Zinc Deficiency
Interventions: DIETARY_SUPPLEMENT: Biofortified wheat|DIETARY_SUPPLEMENT: Fortification|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Asian Subjects With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard Therapy
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: Regorafenib (BAY73-4506)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane Protective Effect on Ischemia Reperfusion Injury in Microvascular Surgery
Status: COMPLETED
Conditions: Microvascular Breast Flap in Plastic Surgery
Interventions: DRUG: Sevoflurane|DRUG: Diprivan + Remifentanil TCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conventional PCNL Versus Tubeless PCNL
Status: UNKNOWN
Conditions: Percutaneous Nephrolithotomy
Interventions: PROCEDURE: percutaneous nephrolithotripsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neovascular Age Related Macular Degeneration (AMD), Periocular Corticosteroids, and Photodynamic Therapy (PDT)
Status: COMPLETED
Conditions: Choroidal Neovascularization|Age-Related Macular Degeneration
Interventions: DRUG: Periocular injection of triamcinolone acetonide 40mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Deltoid Exercises on Injection Site Pain After (BNT162b2) COVID - 19 Vaccination
Status: COMPLETED
Conditions: Vaccines, Adverse Effects|Injection Site Reaction
Interventions: BEHAVIORAL: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Double-Blind Comparison of Naltrexone and Placebo in Adults With Attention Deficit Hyperactivity Disorder
Status: TERMINATED
Conditions: ADHD|Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess CLn® BodyWash for Reducing Skin Fauna in Patients With Hand Eczema
Status: TERMINATED
Conditions: Eczema|Hand Eczema|Atopic Dermatitis
Interventions: OTHER: CLn BodyWash|OTHER: Cetaphil Daily Facial Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PBWST (Partial Body-Weight Supported Treadmill Training) and Muscle Power Training After Sub-acute Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: PROCEDURE: Partial Body-weight supported Treadmill Training|PROCEDURE: PBWST + Power training|PROCEDURE: "Usual" physiotherapy care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI
Status: COMPLETED
Conditions: Glioblastoma
Interventions: RADIATION: Avastin|RADIATION: Lomustine|RADIATION: Temozolomide|DEVICE: MRI|DEVICE: MRS|DEVICE: DSC
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preventing & Treating HIV Comorbidities in India: Multi-tiered Strategy for Women
Status: COMPLETED
Conditions: HIV|Depression
Interventions: BEHAVIORAL: Nurse-delivered mobile phone counseling intervention|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis
Status: COMPLETED
Conditions: Sinusitis, Acute
Interventions: DRUG: FFNS 110 mcg QD|DRUG: FFNS 110 mcg BID|DRUG: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naïve Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV
Status: TERMINATED
Conditions: Chronic Hepatitis C Infection
Interventions: BIOLOGICAL: Pegylated Interferon Lambda-1a|DRUG: Daclatasvir (DCV)|DRUG: Ribasphere (RBV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Previously Received BCG
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: THE EFFECT OF SEX EDUCATION AND COUNSELING GIVEN TO WOMEN WITH STOMIA WITH THE EX-PLISSIT MODEL ON SEXUAL LIFE
Status: NOT_YET_RECRUITING
Conditions: Stoma Colostomy|Stoma Ileostomy
Interventions: OTHER: EDUCATION AND COUNSELING WITH EX-PLISSIT MODEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficiency of Two Different Teaching Methods in Safe Subcutaneous Injection Skills
Status: NOT_YET_RECRUITING
Conditions: Complication of Injection
Interventions: OTHER: video-assisted training group|OTHER: low fidelity simulation model group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Neurofeedback Effectiveness Trial in PTSD
Status: WITHDRAWN
Conditions: PTSD|Post-traumatic Stress Disorder|Cognitive Dysfunction|Cognitive Deficit
Interventions: OTHER: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carillon Mitral Contour System® for Reducing Functional Mitral Regurgitation
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Heart Failure
Interventions: DEVICE: Carillon Mitral Contour System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Impaired Glucose Tolerance in Overweight/Obese Population
Status: RECRUITING
Conditions: Impaired Glucose Tolerance|Overweight|Obese|Prediabetic State
Interventions: OTHER: Acupuncture|OTHER: Sham Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prehospital High-Flow Nasal Oxygen Therapy
Status: COMPLETED
Conditions: Acute Respiratory Failure With Hypoxia|Oxygen Inhalation Therapy|Prehospital Setting
Interventions: DEVICE: High-flow nasal oxygen|DEVICE: Standard oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases
Status: RECRUITING
Conditions: Malignant Neoplasm|Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Neoplasm in the Leptomeninges|Breast Cancer|HER2-positive Breast Cancer
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Topiramate in the Treatment of Obese, Type 2 Diabetes Patients on a Controlled Diet
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus, Type 2|Diabetes Mellitus, Adult-Onset
Interventions: DRUG: topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Protandim on Non-alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-Alcoholic Steatohepatitis
Interventions: DIETARY_SUPPLEMENT: Protandim|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tailored Intervention to Promote Positive Airway Pressure Adherence
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Patient Compliance
Interventions: BEHAVIORAL: Tailored|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COPE, Maternal Competence, Maternal Mental Health, Parent-Infant Interaction and Preterm Neonates
Status: RECRUITING
Conditions: Empowerment|Competence|Outcome|Interaction
Interventions: BEHAVIORAL: Creating Opportunities for Parent Empowerment (COPE) Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate EBA, Safety and Tolerability of Carbapenems in Adults With Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: Meropenem 6g IV over 6 hours|DRUG: Ertapenem 1g IM|DRUG: Meropenem 3g IV|DRUG: Ertapenem 1g IV|DRUG: Amoxicillin/CA twice daily|DRUG: Rifampicin 35 mg/kg|DRUG: Meropenem 6g IV over 60 minutes|DRUG: Rifafour e-275|DRUG: Meropenem 4g IV|DRUG: Amoxicillin/CA once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Spinal Mobilization Versus Myofacial Release Techniques On Pain And Disability In Patients With Tension Type Headache
Status: COMPLETED
Conditions: Tension Type Headache
Interventions: OTHER: Spinal Mobilizations|OTHER: Myofascial Release Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Needle Transducer for Regional Anesthesia Validation Study
Status: RECRUITING
Conditions: Thorax; Pain, Spine, With Radicular and Visceral Pain|Acute Post-thoracotomy Pain|Pain, Postoperative|Ultrasound Therapy; Complications
Interventions: PROCEDURE: Intercostal nerve blocks|PROCEDURE: Paravertebral block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function
Status: RECRUITING
Conditions: Graft-versus-host Disease|Poor Graft Function|Low Donor T-cell Chimerism
Interventions: BIOLOGICAL: Mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Resectable Lung Non-Small Cell Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|RADIATION: Proton Beam Radiation Therapy|OTHER: Radiology, Treatment Planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate and Vitamin C on Vascular Health Oxidative Stress
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Dietary nitrate in the form of beetroot juice for all participnats|DIETARY_SUPPLEMENT: Nature Made vitamin c 1000 mg|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Raynaud's Treatment Study (RTS)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Raynaud's Disease|Vascular Diseases
Interventions: DRUG: nifedipine|BEHAVIORAL: biofeedback (psychology)|PROCEDURE: electromyography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Investigator Initiated, Prospective Study of Xenia Corneal Lenticule
Status: RECRUITING
Conditions: Keratoconus|Post-Laser Retinal Condition
Interventions: DEVICE: Gebauer Lenticule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Recombinant intravesical BCG (Bacillus Calmette-Guérin VPM1002BC)|DRUG: Atezolizumab|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACVBP Followed by ASCT in Patients With BCL-2 Positive Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large-Cell, Diffuse
Interventions: DRUG: doxorubicin|DRUG: cyclophosphamide|PROCEDURE: Autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Preconditioning on Cerebral Circulation Time in Patients With Severe Carotid Artery Stenosis (RIP-CCT)
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: remote ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect Of WCK 2349 on the QT/QTc Interval in Health Volunteers
Status: COMPLETED
Conditions: Qt Interval, Variation in
Interventions: DRUG: WCK 2349|DRUG: Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Investigations on Improving Docosahexaenoic and Arachidonic Acid Content in Preterm Infant Formula
Status: COMPLETED
Conditions: Prematurity of Fetus
Interventions: DIETARY_SUPPLEMENT: low docosahexaenoic acid formula|DIETARY_SUPPLEMENT: medium docosahexaenoic acid formula|DIETARY_SUPPLEMENT: high docosahexaenoic acid formula|DIETARY_SUPPLEMENT: breast milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy
Status: TERMINATED
Conditions: Leukemia
Interventions: DRUG: MEK 162
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sacrospinous Ligament Fixation and Uterosacral Ligament Suspension for Apical Prolapse Surgery: A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Sacrospinous ligament fixation|PROCEDURE: Uterosacral Ligament Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lingualized and Full Bilaterally Balanced Articulation
Status: COMPLETED
Conditions: Jaw, Edentulous
Interventions: PROCEDURE: lingualized occlusion|PROCEDURE: Full Bilaterally Balanced Articulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Apomorphine-induced Skin Reactions: a Pilot Study
Status: TERMINATED
Conditions: Parkinson's Disease|Apomorphine-induced Skin Reactions
Interventions: DRUG: Apomorphine 0.25% (2.5mg/ml)|DEVICE: Massage with a spiky ball|DRUG: Hydrocortisone cream 1%|DRUG: Subcutaneous hydrocortisone 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Two Doses of 18F-AV-45 in Alzheimer's Disease and Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: florbetapir F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: LNZ101 (Aceclidine /Brimonidine) ophthalmic solution|DRUG: LNZ100 (Aceclidine) ophthalmic solution|DRUG: Placebo (Vehicle) ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots
Status: RECRUITING
Conditions: Healthy Aging|Healthy|Healthy Diet
Interventions: DIETARY_SUPPLEMENT: Mitopure|DIETARY_SUPPLEMENT: Pomegranate Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Buparlisib in Metastatic Transitional Cell Carcinoma of the Urothelium
Status: COMPLETED
Conditions: Metastatic Transitional Cell Carcinoma of the Urothelium
Interventions: DRUG: Buparlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COping With PAin Through Hypnosis, Mindfulness and Spirituality
Status: UNKNOWN
Conditions: Pain, Acute
Interventions: BEHAVIORAL: Self-Hypnosis (SH)|BEHAVIORAL: Mindfulness Meditation (MM)|BEHAVIORAL: Christian Prayer (CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Virtual perI-/Menopause Registry of AusTrALia
Status: RECRUITING
Conditions: Menopause|Perimenopausal Disorder|Postmenopausal Symptoms|Health Knowledge, Attitudes, Practice|Healthy Aging|Health Care Utilization|Health Care Seeking Behavior|Mental Health Impairment|Mental Deterioration|Mental Health Issue|Osteoporosis, Postmenopausal|Diabetes Mellitus Risk|Diabetes Mellitus, Type 2|Dementia|Cardiovascular Diseases|Menopause Related Conditions|Hot Flashes|Hot Flushes Aggravated|Economic Burden|Social Stigma
Interventions: OTHER: N/A Observational Registry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of JMT101 in Patients With Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer (mCRC)
Interventions: DRUG: JMT101|DRUG: SG001|DRUG: Irinotecan|DRUG: Regorafenib (Stivarga)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: M2591 25 mg QD|DRUG: M2951 75 mg QD|DRUG: M2951 50 mg BID|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare MultiHance With Gadovist in Magnetic Resonance Imaging (MRI) of the Brain
Status: COMPLETED
Conditions: Brain Lesions
Interventions: DRUG: MULTIHANCE:|DRUG: GADOVIST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 1/2 CTO + Bevacizumab for Recurrent Glioma Post-Bevacizumab Failure
Status: TERMINATED
Conditions: Malignant Glioma (WHO Grade III or IV)
Interventions: DRUG: CTO and Bevacizumab|DRUG: CTO alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Direct Versus US Guided PECS Block on Controlling Postmastectomy Pain
Status: COMPLETED
Conditions: Postmastectomy Pain
Interventions: PROCEDURE: Direct pecs block|PROCEDURE: Ultrasound guided pecs block|DRUG: general anaesthetic technique only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study on the Level of Information on the Risks Related to Tobacco of Persons Consulting in Psychiatry and on Access to Aids in Case of Smoking, Comparing With Persons Consulting in Diabetology or in Addictology
Status: COMPLETED
Conditions: Consumption, Tobacco
Interventions: OTHER: questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Imaging of Brain Amyloid Plaques in the Aging Population
Status: ENROLLING_BY_INVITATION
Conditions: Alzheimer's Disease|Dementia With Lewy Bodies|Frontotemporal Dementia|Vascular Dementia
Interventions: DRUG: Pittsburgh Compound B (C-11 PiB)|DRUG: F-18 FDG|DRUG: Tau (18-F-AV-1451)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Integrating Financial Management Counseling and Smoking Cessation Counseling to Reduce Health and Economic Disparities in Low-Income Immigrants
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Integrated Smoking Cessation and Financial Counseling|BEHAVIORAL: Waitlist Integrated Smoking Cessation and Financial Counseling|DRUG: Nicotine Replacement Therapy (NRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Japan-Working Groups of Acute Myocardial Infarction for the Reduction of Necrotic Damage by a K-ATP
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: nicorandil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Development and Evaluation of a Web-based Childbirth and Parenting Intervention Program
Status: NOT_YET_RECRUITING
Conditions: Parenting|Self Efficacy|Psychological Distress
Interventions: BEHAVIORAL: Web-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevention of Stroke and Sudden Cardiac Death by Recording of 1-Channel Electrocardiograms
Status: UNKNOWN
Conditions: Sinus Rhythm|Atrial Fibrillation|Atrial Premature Complexes|Ventricular Premature Complexes|Ventricular Tachycardia, Nonsustained
Interventions: DIAGNOSTIC_TEST: Electrocardiogram analysis by Artificial Intelligence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quercetin Chemoprevention for Squamous Cell Carcinoma in Patients With Fanconi Anemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Fanconi Anemia|Squamous Cell Carcinoma
Interventions: DRUG: Quercetin (dietary supplement)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial
Status: RECRUITING
Conditions: Pain, Postoperative|Pain, Acute|Pain, Chronic|Fractures, Closed|Fractures, Open
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors
Status: COMPLETED
Conditions: Recurrent Malignant Solid Neoplasm|Recurrent Osteosarcoma|Refractory Malignant Solid Neoplasm|Refractory Osteosarcoma
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pepinemab|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication After Endoscopic Resection of Gastric Tumors
Status: COMPLETED
Conditions: Gastric Tumor|Helicobacter Pylori|Endoscopic Resection|Metachronous Neoplasms
Interventions: DRUG: eradication treatment of Helicobacter pylori infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in Human Immunodeficiency Virus-1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: ABC/DTG/3TC|DRUG: B/F/TAF|DRUG: ABC/DTG/3TC Placebo|DRUG: B/F/TAF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BGB-11417 in Participants With Myeloid Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasm
Interventions: DRUG: BGB-11417|DRUG: Azacitidine|DRUG: Posaconazole|DRUG: BGB-11417|DRUG: BGB-11417
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
Status: NOT_YET_RECRUITING
Conditions: Surgical Blood Loss|Surgical Hemorrhage|Post Operative Hemorrhage
Interventions: DIAGNOSTIC_TEST: Thromboelastography (TEG)|OTHER: Anesthesia Provider Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence of Pancreatic Anomalies of Patients With a 1st Degree Familial History of Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Prevalence of Pancreas Adenocarcinomas
Interventions: PROCEDURE: Pancreatic MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diaphragm Dysfunction and Ultrasound Perioperatively
Status: NOT_YET_RECRUITING
Conditions: Respiratory Insufficiency|Pneumonia|Desaturation of Blood|Tachypnea|Atelectasis, Postoperative
Interventions: DIAGNOSTIC_TEST: Diaphragm ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Two-Tier Care Management Program to Empower Stroke Caregivers in Hong Kong
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Two-Tier Stroke Family Empowerment|OTHER: Volunteer Support Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of SCH 486757 to Codeine and Placebo in Subjects With Persistent Postviral Cough (Study P03069AM2)(COMPLETED)
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: SCH 486757
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sleep, Upper Airway and Dental Occlusion in Children With Large Overjet
Status: ACTIVE_NOT_RECRUITING
Conditions: Overjet, Dental
Interventions: DEVICE: Orthodontic treatment with functional appliance (MAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: SI Joint Stabilization in Long Fusion to the Pelvis
Status: ACTIVE_NOT_RECRUITING
Conditions: Sacroiliac Joint Disruption|Scoliosis Lumbar Region
Interventions: DEVICE: iFuse 3-D in Bedrock Configuration|PROCEDURE: Multilevel Lumbar Fusion surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Analgesic Efficacy of Vitamin B Complex in Critically Ill Obstetrics After Caesarean Section
Status: RECRUITING
Conditions: Analgesia|Post Operative Pain|Cesarean Section
Interventions: DRUG: multimodal analgesia and vitamin B|DRUG: standard multimodal analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Midazolam|DRUG: Repaglinide|DRUG: Dextromethorphan|DRUG: Metformin|DRUG: Ganaplacide|COMBINATION_PRODUCT: Lumefantrine|DRUG: Rosuvastatin|DRUG: Dolutegravir|DRUG: Ganaplacide|COMBINATION_PRODUCT: Lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves).
Status: RECRUITING
Conditions: Mitral Annular Calcification|Mitral Stenosis|Mitral Regurgitation|Mitral Valve Disease
Interventions: DEVICE: Transseptal ViMAC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide After Renal Transplant
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections|Renal Transplant Rejection
Interventions: DRUG: BIKTARVY 50Mg-200Mg-25Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: Semaglutide|DRUG: Placebo (Semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: KRP-104 QD Drug: Placebo Drug: Metformin|DRUG: Placebo Drug: Metformin|DRUG: KRP-104 BID Drug: Placebo Drug: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal Defect
Status: UNKNOWN
Conditions: Perimembranous Ventricular Septal Defect
Interventions: PROCEDURE: transthoracic device closure|PROCEDURE: surgical repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response
Status: TERMINATED
Conditions: Leukemia, Myeloid, Chronic-Phase
Interventions: DRUG: Imatinib Mesylate 600 MG Oral Tablet|DRUG: Imatinib Mesylate 400 MG Oral Tablet|DRUG: Imatinib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Safety and Efficacy of Levetiracetam in the Adjunctive Treatment of Female Subjects With C1 Catamenial Epilepsy
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Levetiracetam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: BIOLOGICAL: Evolocumab|OTHER: Placebo to Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DPX-Survivac Vaccine Therapy in Patients With Recurrent Survivin-expressing DLBCL
Status: TERMINATED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: DPX-Survivac|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Mobile Application for Rehabilitation in Patients With Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain|Chronic Pain
Interventions: OTHER: Exercise follow up with mobile application|OTHER: Home-Based Exercise Program followed by paper booklet|PROCEDURE: Electrotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Camrelizumab Combined With Ablation and Chemotherapy in Patients With Pancreatic Cancer Liver Metastasis（SHR-1210-HLJ-009）
Status: WITHDRAWN
Conditions: Pancreatic Cancer|Liver Metastasis
Interventions: DRUG: Camrelizumab|DRUG: Chemotherapy|PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Stem Cell Treatment of Patients With Vocal Fold Scarring
Status: COMPLETED
Conditions: Improved Healing of Scarred Vocal Folds|Improved Vocal Fold Status|Improved Vocal Fold Function
Interventions: BIOLOGICAL: aMSC|BIOLOGICAL: aMSC+hyaluronan gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclin dEpendent Kinase in tRiple nEGatIVe brEast canceR - a "Window of Opportunity" Study
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Palbociclib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin and Enhancement of Team Cohesion
Status: COMPLETED
Conditions: Unit Cohesion
Interventions: DRUG: Oxytocin|OTHER: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-term Study of Alogliptin as an Add-on to Rapid-Acting Insulin Secretagogues in Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Alogliptin|DRUG: Rapid-acting insulin secretagogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Gemcitabine, Cisplatin, Epirubicin, and Capecitabine in Treating Patients With Stage I-II Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: epirubicin|DRUG: gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydros and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Hydros|DEVICE: Hydros-TA|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CARDINAL- A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Chronic Myeloid Leukemia, Chronic Phase|Chronic Myeloid Leukemia
Interventions: DRUG: TERN-701
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT