pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution
Status: RECRUITING
Conditions: Atherosclerosis|Coronary Artery Disease|Peripheral Arterial Disease|Ischemic Stroke|Carotid Artery Diseases
Interventions: OTHER: Hybrid strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Examine the Safety, Pharmacokinetics and Pharmacodynamics of Single Dose of AMG 623 in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: AMG 623|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Dental Implant Position Robotic Assistance, Dynamic Navigation, or Static Guide?
Status: RECRUITING
Conditions: Dental Implant
Interventions: DEVICE: Static guide|DEVICE: Dynamic navigation|DEVICE: Robotic system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus Somatostatin Analogue and Metronomic Capecitabine in Patients With Advanced Neuroendocrine Tumors
Status: UNKNOWN
Conditions: Neuroendocrine Carcinomas
Interventions: DRUG: bevacizumab + octreotide LAR + capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
Status: RECRUITING
Conditions: DOCK8 Deficiency
Interventions: PROCEDURE: Reduced-intensity hematopoietic stem cell|DRUG: Fludarabine(Fludara, Berlex Laboratories)|DRUG: Cyclophosphamide(CTX, Cytoxan)|PROCEDURE: Total Body Irradiation (TBI)|DRUG: Busulfan (Busulfex)|PROCEDURE: Donor peripheral blood stem cell mobiliation and collection|PROCEDURE: Bone Marrow Harvest Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparision of M-TAPA Versus TAPB After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain, Acute
Interventions: PROCEDURE: Type of interfascial plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Thiazolidinedione Treatment Vascular Risk Markers
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Vascular Diseases
Interventions: DRUG: Rosiglitazone|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of Laparoscopic Sleeve Gastrectomy and Gastric Bypass for Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity|Metabolic Syndrome X|Diabetes Mellitus|Dyslipidemia|Hypertension
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|PROCEDURE: Roux-en-Y Gastric Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training Using an App on Physical Cardiovascular Function Individuals With Post-covid-19 Syndrome
Status: RECRUITING
Conditions: Post-Acute COVID-19 Syndrome
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aloe Vera Versus Thyme Honey Mouthwash in Management of Xerostomia in Type 2 Diabetics
Status: ACTIVE_NOT_RECRUITING
Conditions: Xerostomia
Interventions: DRUG: Aloevera|DRUG: Thyme honey|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of a Proactive Clinical Management and Early Diagnosis of Arrhythmias in Patients With Heart Failure and Non Severely Reduced Left Ventricular Function Through a Telemonitoring System
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Arrhythmias, Cardiac
Interventions: DEVICE: implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Theta-burst Stimulation on Serum BDNF
Status: RECRUITING
Conditions: Gambling Disorder
Interventions: DEVICE: Theta Burst Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HAT1 Compared to Calcipotriol in Patients With Mild to Moderate Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: HAT1|DRUG: Calcipotriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate Safety of Allogeneic Bone Marrow Derived Mesenchymal Stem Cell in Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease Stage 3B|Chronic Kidney Disease stage4
Interventions: BIOLOGICAL: Cellgram-CKD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intramuscular Injection of Xiyanping Injection in the Treatment of Acute Bronchitis in Children
Status: UNKNOWN
Conditions: Acute Bronchitis in Children
Interventions: DRUG: Xiyanping injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D in Bronchiolitis Obliterans Syndrome
Status: COMPLETED
Conditions: Allograft Rejection|Lung Transplantation|Bronchiolitis Obliterans
Interventions: DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Ultrasound-guided Hyaluronic or Corticosteroid Injections in Patients With Chronic Subacromial Bursitis
Status: COMPLETED
Conditions: Shoulder Pain|Subdeltoid Bursitis|Subacromial Bursitis
Interventions: DRUG: corticosteroids|DRUG: hyaluronic acid|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress
Status: COMPLETED
Conditions: Depressive Disorder|Depression|Depressive Disorder, Major|Mood Disorders|Mental Disorders
Interventions: DRUG: Placebo + ADT|DRUG: Brexpiprazole +ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Positive Psychology Intervention to Improve Quality of Life in Stem Cell Transplant Survivors and Their Caregivers
Status: COMPLETED
Conditions: Hematopoietic Cell Transplantation Recipient
Interventions: BEHAVIORAL: Booklet|BEHAVIORAL: Exercise Intervention|OTHER: Quality-of-Life Assessment|OTHER: Survey Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combined Sono-electro-magnetic Therapy for Treatment of Refractory Chronic Pelvic Pain Syndrome
Status: COMPLETED
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DEVICE: combined sono-electro-magnetic therapy (Sonodyn Medico Star)|DEVICE: placebo therapy (Placebo Sonodyn Medico Star)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single-Blind Trial of Risperidone vs. Paroxetine for Treatment of Panic Attacks
Status: COMPLETED
Conditions: Major Depression With Panic Attacks|Panic Disorder
Interventions: DRUG: Paroxetine|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Lipo-prostaglandin E1 Improves Renal Hypoxia Evaluated by BOLD-MRI in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Lipo-PGE1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between TOF Watch® SX and Tetragraph®
Status: COMPLETED
Conditions: Neuromuscular Blockade|Neuromuscular Monitoring
Interventions: DEVICE: Tetragraph® (Senzime, Uppsala, Sweden)|DEVICE: TOF Watch® SX (Organon Teknika B.V., Boxtel, Holland)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 6 Weeks Plyometric Training on Vertical Jump and Agility in Relation to Gender Among Badminton Players
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: Plyomtric training to male badmninton players|OTHER: Plyomtric training to female badmninton players
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Diagnostic Approach of Early Atrial Fibrillation, Silent Stroke and Cognitive Disorder in Patients With High-risk
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Fibrillation New Onset|Dementia|Stroke
Interventions: DEVICE: Electrocardiogram
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Flotetuzumab in Treating Patients With Recurrent or Refractory CD123 Positive Blood Cancer
Status: WITHDRAWN
Conditions: Acute Biphenotypic Leukemia|Acute Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Hairy Cell Leukemia|Interleukin-3 Receptor Subunit Alpha Positive|Recurrent Acute Lymphoblastic Leukemia|Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Hematologic Malignancy|Recurrent Hodgkin Lymphoma|Refractory Acute Lymphoblastic Leukemia|Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm|Refractory Hematologic Malignancy|Refractory Hodgkin Lymphoma|Systemic Mastocytosis
Interventions: BIOLOGICAL: Anti-CD123/CD3 Monoclonal Antibody MGD006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Covering of the Abdominal Wall in Laparotomies: Differences in Surgical Site Infections Between an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven Swabs at Technische Universität München
Status: COMPLETED
Conditions: Comparing the Number of Surgical Site Infections|Covering of the Abdominal Wall in Laparotomies With an Approved Abdominal 3M™ Steri-Drape™ Wound Edge Protector and Standard Woven|Swabs
Interventions: PROCEDURE: Intervention Arm 1: Covering with approved abdominal 3M™ Steri-Drape™ Wound Edge Protector Intervention Arm 2: Covering with standard woven swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Symptom Screening With Targeted Early Palliative Care (STEP) Versus Usual Care for Patients With Advanced Cancer
Status: TERMINATED
Conditions: Cancer
Interventions: BEHAVIORAL: Symptom screening with Targeted Early Palliative Care (STEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) Children
Status: TERMINATED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Binge Eating and Chromium Study
Status: COMPLETED
Conditions: Binge Eating Disorder
Interventions: DIETARY_SUPPLEMENT: Sugar Pill|DIETARY_SUPPLEMENT: chromium picolinate|DIETARY_SUPPLEMENT: chromium picolinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study of Sunitinib Malate Capsules.
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors|Renal Cell Carcinoma|Pancreatic Neuroendocrine Tumor
Interventions: DRUG: Sunitinib malate capsules generic product|DRUG: Sunitinib malate capsules reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68-Ga-labeled Octreotide Analogues PET in Duodenal-pancreatic Neuroendocrine Tumours
Status: COMPLETED
Conditions: Neuroendocrine Tumours
Interventions: DRUG: Diagnostic work up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pilot Study to Evaluate the Feasibility of Combining Submandibular Salivary Gland Tx & IMRT Tomo to Reduce Xerostomia
Status: UNKNOWN
Conditions: Head and Neck Cancer
Interventions: PROCEDURE: Salivary gland transfer|PROCEDURE: Helical Tomotherapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pantoprazole on the Symptoms of Acid Reflux Disease in Adult Patients (BY1023/M3-341)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial With HuMax-CD4 in Participants With Rheumatoid Arthritis (RA) Failing Treatment With Methotrexate (MTX) and a TNF-alpha Blocker
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: HuMax-CD4|DRUG: Placebo|DRUG: Humax-CD4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: NI-071|DRUG: Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Efficacy of Fibrin Sealant Grifols as an Adjunct to Haemostasis During Surgery in Paediatric Participants
Status: COMPLETED
Conditions: Excessive Bleeding During Surgery
Interventions: BIOLOGICAL: Fibrin Sealant Grifols|BIOLOGICAL: EVICEL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Methadone Versus Morphine for Orthopedic Surgery Patients
Status: COMPLETED
Conditions: Fracture|Pain, Postoperative
Interventions: DRUG: Methadone|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrovirus Epidemiology Donor Study-II (REDS-II)
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|Blood Donors|Blood Transfusion|HIV Infections|HIV-1|HIV-2|HTLV-I|HTLV-II|Retroviridae Infections|Hepatitis, Viral, Human|Hepatitis B|Hepacivirus|West Nile Virus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Distal Radial Access for Coronary Procedures
Status: RECRUITING
Conditions: Vascular Access Complication|Coronary Artery Disease|STEMI|Non STEMI|Angina, Unstable|Angina, Stable|Artery Occlusion|Hematoma|Procedural Pain|Procedural Blood Vessel Puncture
Interventions: PROCEDURE: Distal radial access
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 2, Endocrine Therapy + OSI-906 With or Without Erlotinib for Hormone-sensitive Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: IGF-1R inhibitor OSI-906|DRUG: erlotinib hydrochloride|DRUG: goserelin|DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and the Safety of Regorafenib in Patients Aged More Than 70 Years With a Metastatic Colorectal Adenocarcinoma .
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: Regorafenib 160 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans
Status: COMPLETED
Conditions: Periodontitis
Interventions: DEVICE: DFDBA|DEVICE: autologous platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: WITHDRAWN
Conditions: Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IIA Fallopian Tube Cancer|Stage IIA Ovarian Cancer|Stage IIB Fallopian Tube Cancer|Stage IIB Ovarian Cancer|Stage IIC Fallopian Tube Cancer|Stage IIC Ovarian Cancer|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Recombinant NY-ESO-1 Protein|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-pulse Subthreshold vs Infrared Micropulse for Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: Macular Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Assessment of Cognitive Improvement Training Among Mid-life Individuals
Status: RECRUITING
Conditions: Delay Discounting
Interventions: BEHAVIORAL: Sequenced Recall of Digits--Auditory|BEHAVIORAL: Sequenced Reverse Recall of Digits--Auditory|BEHAVIORAL: Sequenced Recall of Words--Visual|BEHAVIORAL: Verbal Memory--Visual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of New CI Delivery Models in an Adult Nucleus CI Population
Status: COMPLETED
Conditions: Sensorineural Hearing Loss, Bilateral|Cochlear Implant
Interventions: DEVICE: Commercially available cochlear implant and AI system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Translantation (FMT) to Reduce Inflammation in PLWH: The Gutsy Pilot Study
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: BIOLOGICAL: FMT capsules|BIOLOGICAL: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Stress and the Nervous System
Status: UNKNOWN
Conditions: Autonomic Nervous System|Baroreflex|Stress, Physiological
Interventions: DRUG: Cosyntropin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Neoadjuvant Treatment|Debulking Surgical Procedures
Interventions: DRUG: Olaparib|DRUG: Platinum-based Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients
Status: ENROLLING_BY_INVITATION
Conditions: Dysphagia Following Cerebrovascular Accident
Interventions: OTHER: high intensity dysphagia therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Locked Non-barbed Suture for Mesh Fixation During Laparoscopic Sacral Colpopexy for Severe Pelvic Organ Prolapse
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Continuous Locked Suture vs Traditional 5-points suture for Laparoscopic Sacral Colpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl in Pain Alleviation and Healing of Alveolar Osteitis
Status: RECRUITING
Conditions: Osteitis|Dry Socket
Interventions: DRUG: Ozone gel|DRUG: doxycycline hyclate saturated chitosan dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiphospholipid Syndrome and Postpartum Pulmonary Artery Pressure
Status: RECRUITING
Conditions: Pre-Eclampsia; Complicating Pregnancy|Antiphospholipid Syndrome in Pregnancy|Pulmonary Hypertension
Interventions: DIAGNOSTIC_TEST: Echocardiography images|DIAGNOSTIC_TEST: 24-hour ambulatory blood pressure monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess Safety and Efficacy of Avalglucosidase Alfa Administered Every Other Week in Pediatric Patients With Infantile-onset Pompe Disease Previously Treated With Alglucosidase Alfa
Status: ACTIVE_NOT_RECRUITING
Conditions: Glycogen Storage Disease Type II-Pompe's Disease
Interventions: DRUG: Avalglucosidase alfa (GZ402666)|DRUG: Alglucosidase alfa (GZ419829)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Dementia|Cognition Disorders|Cerebral Ischemic Events
Interventions: DRUG: Dabigatran Etexilate|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Extension Study to Demonstrate the Equivalence of Long-Term Efficacy and Safety of CT-P13 in Patients With Ankylosing Spondylitis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 1.1
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Dimethyl Sulfoxide Dentin Pre-treatment
Status: COMPLETED
Conditions: Dental Diseases
Interventions: OTHER: Dimethyl Sulfoxide|OTHER: 3M ESPE Single bond 2|OTHER: Filtek Z350 XT, 3 M ESPE, St Paul, MN, USA)|OTHER: 3m ESPE etch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Cardiac Effects of Danicopan in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Danicopan|DRUG: Moxifloxacin-matching Placebo|DRUG: Danicopan-matching placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Feasibility Study for Evaluating the Effectiveness of Mindhelper - a National Youth Mental Health Promotion Website
Status: COMPLETED
Conditions: Mental Health Issue|Young Adult|Feasibility Studies|Randomized Controlled Trial|Internet-Based Intervention|Recruitment
Interventions: BEHAVIORAL: Mindhelper - a national youth mental health promotion website
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Contribution of SA and Coma to The Total Ocular HOA Before and After FS-LASIK Using An Aspheric Ablation Profile
Status: UNKNOWN
Conditions: FS-LASIK Surgery Effect on Higher Order Aberrations
Interventions: PROCEDURE: LASIK refractive surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluating the Safety of and Immune Response to the VSV-Indiana HIV Vaccine in Healthy, HIV-Uninfected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VSV-Indiana HIV gag vaccine|BIOLOGICAL: Placebo injection (normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of GPC-3 CAR-T Cells in Treating With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: BIOLOGICAL: GPC3 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia|Acute Myeloid Leukemia, in Relapse
Interventions: DRUG: Bomedemstat|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Providing Specialty Care to Individuals With Parkinsonism Directly in Their Homes Via Web-based Video Conferencing- A Comparative Effectiveness Study
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: OTHER: Telemedicine|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Efficacy and Safety of Different Doses of Bimekizumab in Subjects With Active Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Placebo|DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of a New Polycationic Disinfectant on Clostridium Difficile Incidence and Environmental Colonisation
Status: COMPLETED
Conditions: Clostridium Difficile
Interventions: OTHER: Polyhexamethyleneguanidine (PHMG)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: ACE/ARB continuation|DRUG: ACE/ARB withdrawal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sjögren's Syndrome Is Associated With Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction|Sjögren's Syndrome
Interventions: DRUG: liposic|DRUG: Tears Naturale Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer
Status: COMPLETED
Conditions: Mucinous Adenocarcinoma of the Rectum|Recurrent Rectal Cancer|Signet Ring Adenocarcinoma of the Rectum|Rectal Adenocarcinoma|Stage IIA Rectal Cancer|Stage IIB Rectal Cancer|Stage IIC Rectal Cancer|Stage IIIA Rectal Cancer|Stage IIIB Rectal Cancer|Stage IIIC Rectal Cancer
Interventions: RADIATION: intensity-modulated radiation therapy|DRUG: fluorouracil|DRUG: oxaliplatin|DRUG: leucovorin calcium|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Endoscopic Versus Open Harvest of the Radial Artery in Coronary Artery Bypass Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Endoscopic Radial Artery Harvest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Incidence of Inadequate Epidural Analgesia Between Protocol Based and Current Practice
Status: TERMINATED
Conditions: Epidural Analgesia|Postoperative Pain
Interventions: DRUG: Current practice|DRUG: Protocol based
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Rofecoxib and Prolonged Constant Infusion of Gemcitabine in the Polychemotherapy Treatment of Advanced NSCLC
Status: COMPLETED
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: gemcitabine|DRUG: prolonged continuous infusion gemcitabine|DRUG: cisplatin|DRUG: rofecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia
Status: RECRUITING
Conditions: Oxygenation Index
Interventions: DRUG: 80% Oxygen|DRUG: 40% Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Efficacy and Safety of Hyaluronic Acid Injection on Skin Moisturization and Elasticity
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Injection of STYLAGE® HydroMax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Imaging Malignant Glioma With 68Ga-DOTATOC PET/CT
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: [68Ga]DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PEA Promote Gastrointestinal Function Recovered After Colorectal Cancer Operation
Status: RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Routine perioperative management and PEA|PROCEDURE: Routine perioperative management and postEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetrorelix Pamoate IM Regimens in Patients With Symptomatic Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Benign Prostatic Hypertrophy
Interventions: DRUG: Cetrorelix Pamoate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study
Status: COMPLETED
Conditions: Aging|Cognitive Ability, General
Interventions: BEHAVIORAL: Moderate-aerobic walking|RADIATION: Positron Emission Tomography (PET) scan|BEHAVIORAL: Healthy living education|DEVICE: Physical activity monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Forward Head Posture Correction on Visual Acuity in Low Level Visually Impaired University Students
Status: COMPLETED
Conditions: Visual Acuity
Interventions: OTHER: POSTURAL CORRECTION four exercises|OTHER: postural Correction education with a manuscript
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage IIIB Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: DRUG: Alisertib|DRUG: Osimertinib|DRUG: Sapanisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection of Transplant Stem Cells for Plasma Cell Myeloma
Status: COMPLETED
Conditions: Plasma Cell Myeloma|Multiple Myeloma
Interventions: DRUG: Filgrastim|DRUG: Plerixafor|PROCEDURE: Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Esketamine on Anxiety State in Patients Undergoing Abdominal Tumor Surgery
Status: RECRUITING
Conditions: Anxiety State|Esketamine
Interventions: DRUG: Esketamine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study of JNJ-64457744
Status: TERMINATED
Conditions: Healthy|Hepatitis B, Chronic
Interventions: DRUG: JNJ-64457744|DRUG: Placebo|DRUG: Tenofovir Disoproxil Fumarate (TDF)|DRUG: Tenofovir Alafenamide (TAF)|DRUG: Entecavir (ETV)|DRUG: JNJ-64457744
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENdometrial Cancer SURvivors' Follow-up carE (ENSURE): Less is More?
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: OTHER: Reduced follow-up schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With Prostate Cancer After Undergoing Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: RADIATION: stereotactic body radiation therapy|PROCEDURE: quality-of-life assessment|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Bevacizumab Before vs After Pattern Panretinal Photocoagulation
Status: TERMINATED
Conditions: Macular Edema
Interventions: DRUG: bevacizumab|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent
Status: COMPLETED
Conditions: Chronic Viral Hepatitis B With Delta-agent
Interventions: DRUG: Myrcludex B|DRUG: PEG IFN alfa-2a|DRUG: Tenofovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions
Status: COMPLETED
Conditions: 22q11.2 Deletion Syndrome
Interventions: DRUG: NFC-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perineural Injection Therapy for Ulnar Neuropathy at Elbow
Status: COMPLETED
Conditions: Ulnar Neuropathy at Elbow
Interventions: DRUG: 5% dextrose|DRUG: 2cc 0.9% normal saline+3cc Triamcinolone (30mg)|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band
Status: UNKNOWN
Conditions: Stuttering, Adult|Stammering
Interventions: DEVICE: ZOV.ai digital therapy candidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the Skin
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: DRUG: NNC0487-0111|DRUG: Placebo (NNC0487-0111)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ZN-c3 for the Treatment of Metastatic Triple-Negative Breast Cancer and Advanced Ovarian Cancer
Status: WITHDRAWN
Conditions: Advanced Fallopian Tube Carcinoma|Advanced Ovarian Carcinoma|Advanced Primary Peritoneal Carcinoma|Anatomic Stage IV Breast Cancer AJCC v8|Metastatic Triple-Negative Breast Carcinoma|Stage III Fallopian Tube Cancer AJCC v8|Stage III Ovarian Cancer AJCC v8|Stage III Primary Peritoneal Cancer AJCC v8|Stage IV Fallopian Tube Cancer AJCC v8|Stage IV Ovarian Cancer AJCC v8|Stage IV Primary Peritoneal Cancer AJCC v8
Interventions: DRUG: Wee1 Inhibitor ZN-c3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PatientCareAnywhere Internet-Based Software in Improving Communication and Education in Patients With Cancer and Their Healthcare Providers
Status: COMPLETED
Conditions: Bladder Carcinoma|Breast Carcinoma|Colorectal Carcinoma|Lung Carcinoma|Malignant Female Reproductive System Neoplasm|Malignant Neoplasm
Interventions: OTHER: Communication Intervention|OTHER: Educational Intervention|OTHER: Internet-Based Intervention|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LCI-HEM-MYE-CRD-002: Carfilzomib-Revlimid-Dexamethasone-Elotuzumab in Relapsed/Refractory Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Elotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir/Velpatasvir Fixed-Dose Combination in HCV-Infected Adults Who Are Undergoing Liver Transplantation
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: SOF/VEL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parents' View About Discussing Health Behaviors
Status: COMPLETED
Conditions: Parents of Children Ages 10 to 17 Years Old
Interventions: BEHAVIORAL: Discussion Tool: Unhealthy Eating|BEHAVIORAL: Discussion Tool: Marijuana Use|BEHAVIORAL: Discussion Tool: Sedentary Behavior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Neoadjuvant Treatment Associated With Maintenance Therapy by Anti-PD1 Immunotherapy in Patients With Resectable Head and Neck Mucosal Melanoma
Status: RECRUITING
Conditions: Head and Neck Mucosal Melanomas
Interventions: DRUG: Pembrolizumab|PROCEDURE: Surgery|RADIATION: IMRT|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membrane
Interventions: DRUG: Cefazolin|DRUG: Clarithromycin|DRUG: Cefazolin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Auditory Interventions On Pain And Comfort In Premature Infants
Status: COMPLETED
Conditions: Premature Birth|Premature Infant
Interventions: OTHER: RECORDED MOTHER'S VOICE|OTHER: White Noise|OTHER: MiniMuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase IV, Open-label, Multicenter Study of Dasatinib in Chronic-Phase Chronic Myeloid Leukemia (CP-CML) Patients With Chronic, Low-grade Non-Hematologic Toxicity to Imatinib
Status: COMPLETED
Conditions: Chronic Phase Chronic Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions
Status: NOT_YET_RECRUITING
Conditions: Aortic Dissection Type B|Intramural Hematoma|Penetrating Aortic Ulcer
Interventions: DEVICE: Cratos™ Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Long-term Safety of VX-445 Combination Therapy
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Status: RECRUITING
Conditions: Depressive Disorder, Major
Interventions: DRUG: Seltorexant|DRUG: Placebo|DRUG: Selective Serotonin Reuptake Inhibitor (SSRI)/Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Impact and Intervention for Diarrhea in Brazil
Status: UNKNOWN
Conditions: Diarrheal Disorder
Interventions: DRUG: Glutamine|DRUG: Vitamin A|DRUG: glycine|DRUG: zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion
Status: COMPLETED
Conditions: Unwanted Pregnancies
Interventions: DRUG: methotrexate + misoprostol|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434
Status: RECRUITING
Conditions: Hepatic Impairment|Cirrhosis
Interventions: DRUG: VIR-2218|DRUG: VIR-3434
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib and Adebrelimab Combined With GEMOX in the Perioperative Treatment of Potentially Resectable Intrahepatic Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Clofarabine in Combination With Low Dose Cytarabine to Treat Myelodysplastic Syndromes
Status: WITHDRAWN
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Clofarabine plus low dose Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Follow-Up Study of Mesenchymal Stem Cells for Bronchopulmonary Dysplasia
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: transplantation of hUC-MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a XIENCE V® Endoprothesis Used for Coronary Angioplasty, for LPPR (List of Reimbursable Products and Services) Indications in Patients Monitored for 2 Years in France
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: XIENCE V®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of 8 Weeks Moderate and High Intensity Training on Hemoglobin Levels of Female Students
Status: COMPLETED
Conditions: Moderate and High Intensity Training and Hemoglobin Levels
Interventions: OTHER: moderate intensity|OTHER: High intensity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tissue Sample Study for Mitochondrial Disorders
Status: ENROLLING_BY_INVITATION
Conditions: Mitochondrial Disorders|Mitochondrial Disease|Melas|Kearns Sayer|NARP|MNGIE|LHON|Mitochondrial Depletion Syndrome|Leigh's Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Smoke-Free Living Study
Status: COMPLETED
Conditions: Additional, Effective Methods to Stop Smoking
Interventions: BEHAVIORAL: Extended IVR (integrated voice response technology)|DRUG: Varenicline (Champix)|BEHAVIORAL: IVR treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT