pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Figure-Of-Eight Suture Perclose ProGlide Suture-Mediated Closure
Status: COMPLETED
Conditions: Venous Puncture
Interventions: OTHER: Figure-of-eight suture|OTHER: Perclose Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Influence of Glutamate on Memory in Humans
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: DRUG: Sugar pill|DRUG: Sugar pill|DRUG: Sugar pill|DRUG: Sugar pill|DRUG: Glutamic Acid|DRUG: Glutamic Acid|DRUG: Memantine|DRUG: Memantine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Fludarabine, busulfan and melphalan|DRUG: Fludarabine and Busulfan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Metal Versus Plastic Stents for Preoperative Biliary Decompression
Status: COMPLETED
Conditions: Obstructive Jaundice|Pancreatic Cancer
Interventions: PROCEDURE: Stent Dysfunction|PROCEDURE: Complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concor® Bioequivalence Study in Chinese Participants (Darmstadt-Nantong)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: First Test Concor (Fasted)|DRUG: First Reference Concor (Fasted)|DRUG: First Test Concor (Fed)|DRUG: First Reference Concor (Fed)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children
Status: COMPLETED
Conditions: Pain, Postoperative|Appendicitis
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compassionate Use of Brontictuzumab for Adenoid Cystic Carcinoma (ACC)
Status: COMPLETED
Conditions: Adenoid Cystic Carcinoma
Interventions: DRUG: Brontictuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of High-dose Zinc Therapy and Albendazole in the Treatment of Environmental Enteropathy
Status: COMPLETED
Conditions: Enteropathy
Interventions: DRUG: Albendazole|DRUG: Placebo|DIETARY_SUPPLEMENT: High-dose Zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Partners for Pain & Wellbeing Equity: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain
Status: COMPLETED
Conditions: Neck Pain|Low Back Pain|Chronic Pain
Interventions: OTHER: Partners4Pain program|OTHER: Key to Wellbeing program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Intracoronary Injection of Eptifibatide in Primary Coronary Intervention in STEMI Patients
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Eptifibatide|DRUG: Eptifibatide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Intraoperative Taping on the Control of Edema Resulting From Stripping
Status: NOT_YET_RECRUITING
Conditions: Edema|Varices; Cord
Interventions: PROCEDURE: Transoperative taping|OTHER: No trasoperative taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tangji EU Gastric Bypass Stent Study for Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity
Interventions: DEVICE: A prospective, open-label, multicenter, single-arm clinical study to evaluate the safety and performance of the Gastric Bypass Stent System as a weight loss treatment for obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Colonoscopy Bowel Preparation With Clear Liquids, With and Without Two Servings of High Energy Nutritional Supplement
Status: COMPLETED
Conditions: Colonoscopy|Bowel Preparation
Interventions: DIETARY_SUPPLEMENT: Resource® Energy Apricot|OTHER: Bowel preparation as usual.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical, Radiological, Histologic and Molecular Features of a Cohort of Melanocytic Tumors of the Central Nervous System
Status: RECRUITING
Conditions: Meningeal Melanocytoma|Meningeal Melanomatosis|Meningeal Melanocytosis|Meningeal Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of the Administration of Ornithine Phenylacetate in Patients With Cirrhosis and Upper Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Gastrointestinal Bleeding|Cirrhosis
Interventions: DRUG: Ornithine-phenylacetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Effectiveness and Safety of Amberen and Smart B by Women With Climacteric Syndrome
Status: COMPLETED
Conditions: Climacteric Syndrome|Menopause
Interventions: DIETARY_SUPPLEMENT: Amberen|DIETARY_SUPPLEMENT: Smart B|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B16D1 in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Solid Tumors
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinomas|Solid Tumor
Interventions: DRUG: BL-B16D1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SEQUence of Endocrine Therapy in Advanced Luminal Breast Cancer (SEQUEL-Breast)
Status: RECRUITING
Conditions: Neoplasm, Breast|Congenital, Familial and Genetic Disorders
Interventions: DRUG: Alpelisib 150 MG Oral Tablet [Piqray]|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QLB vs. Wound Infiltration in Cesarean Section
Status: COMPLETED
Conditions: Analgesia|Cesarean Section
Interventions: DRUG: Quadratus Lumborum Block type 2|DRUG: Wound Infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Versus Delayed Artificial Rupture of Membranes (AROM Trial)
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: PROCEDURE: amniotomy|DEVICE: Foley Catheter|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of HS-20094 in T2DM Participants
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: HS-20094 5mg|DRUG: HS-20094 10mg|DRUG: HS-20094 15mg|DRUG: HS-20094 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Using Dienogest and N-Acetyl Cysteine on the Volume of Uterine Leiomyoma
Status: RECRUITING
Conditions: Uterine Leiomyoma
Interventions: DRUG: Dienogest 2 MG|DRUG: N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clofarabine and Low Dose Total Body Irradiation as a Preparative Regimen for Stem Cell Transplant in Leukemia.
Status: COMPLETED
Conditions: Leukemia Lymphoblastic, Acute|Acute Myeloid Leukemia|Neoplasm Recurrent
Interventions: DRUG: Clofarabine|RADIATION: Total Body Irradiation|OTHER: Stem Cell Transplantation|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Melphalan for Use With Hepatic Delivery System Treatment Followed by Sorafenib in Patients With Unresectable HCC
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DEVICE: Melphalan/HDS|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Training for Children With Attention-Deficit/Hyperactivity Disorder (ADHD) and Mindful Parenting
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: OTHER: MYmind mindfulness training|OTHER: Care-as-usual for children (8-16 years old) with ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Naltrexone Therapy for Promoting Adherence to Oral Naltrexone vs Extended Release Injectable Depot Naltrexone
Status: COMPLETED
Conditions: Opiate Dependence|Heroin Dependence
Interventions: DRUG: depot naltrexone|DRUG: Oral Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Use of Adjuvant Drugs After Extracorporeal Shockwave Lithotripsy (ESWL) in Renal Calculus
Status: UNKNOWN
Conditions: Renal Calculi
Interventions: DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of Left Ventricular Ejection Fraction Using Cardiac Angioscintigraphy
Status: UNKNOWN
Conditions: Angioscintigraphy|Tomoscintigraphy
Interventions: DRUG: stannous pyrophosphate|DRUG: Technetium-99m|DEVICE: E-CAM Camera|DEVICE: CZT Semiconductor Camera (D-SPECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The P-KIDs CARE Health Systems Intervention in Tanzania
Status: NOT_YET_RECRUITING
Conditions: Accidental Injuries|Global Child Health|Pediatric Emergency Medicine|Public Health System Research|Health Care Providers|Implementation Science
Interventions: OTHER: P-KIDs CARE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Partial Chest Wall Radiation Therapy After Surgery for Lymph Node Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer|Breast Cancer Female|DCIS|Stage II Breast Cancer|Stage I Breast Cancer
Interventions: RADIATION: Partial Chest Wall Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Lateral Wedge Insole on Knee Osteoarthritis Outcomes in Pakistani Population
Status: COMPLETED
Conditions: Medial Compartment Knee Osteoarthritis
Interventions: OTHER: Lateral wedge insoles with home exercises group(Group 1)|OTHER: Traditional physiotherapy with home exercises group (Group 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas
Status: ACTIVE_NOT_RECRUITING
Conditions: Neurofibromatosis 1|Plexiform Neurofibroma (PN)
Interventions: DRUG: Selumetinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Defining the Molecular and Physiological Mechanisms of Pancreatic Islet Cell Dysfunction Which Lead to Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: OTHER: Glucose-Potentiated Arginine-Induced Insulin Secretion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Neuromuscular Training on Functional Capacity in Acute Coronary Syndrome Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: Neuromuscular training|OTHER: Conventional strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Double-blind, Placebo-controlled Phase IIb Trial to Test FLU-v Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FLU-v|BIOLOGICAL: adjuvanted FLU-v|BIOLOGICAL: Saline|BIOLOGICAL: Adjuvanted placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: atorvastatin|DRUG: Acetylcysteine|DRUG: Danazol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)
Status: RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: delandistrogene moxeparvovec|GENETIC: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Study of AK127 in Combination With AK112 in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: AK127 in combination with AK112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single vs Double Symphyseal Plating in Management of Vertically Unstable Open Book Pelvic Ring Injuries:
Status: ACTIVE_NOT_RECRUITING
Conditions: Evaluation of Single Symphyseal Plating in APC III Injuries
Interventions: PROCEDURE: single symphyseal plating in management of vertically unsable open book pelvic ring injuries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Passive Heat on Metabolic, Inflammatory and Vascular Health in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Chronic Inflammation|Glucose Metabolism|Endothelial Function
Interventions: OTHER: passive heat stress|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Impact of Epidural Fat Resection on Postoperative Outcomes in Posterior Surgery of Lumbar Spine
Status: COMPLETED
Conditions: Spinal Stenosis
Interventions: PROCEDURE: Resection of epidural fat|PROCEDURE: No resection of epidural fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Re-expression of ER in Triple Negative Breast Cancers
Status: TERMINATED
Conditions: Breast Cancer|Breast Tumors|Breast Neoplasms
Interventions: DRUG: Decitabine, LBH589, Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Transcutaneous Spinal Cord Stimulation on Residual Voluntary Motor Control in Individuals With Incomplete Spinal Cord Injury
Status: COMPLETED
Conditions: Motor Control in Incomplete Spinal Cord Injured Persons
Interventions: DEVICE: Transcutaneous electrical spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions
Status: COMPLETED
Conditions: Papilloma|Cervix Lesion
Interventions: DIETARY_SUPPLEMENT: Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Use of Ferric Carboxymaltose With Placebo in Patients With Chronic Heart Failure and Iron Deficiency
Status: COMPLETED
Conditions: Iron Deficiency|Chronic Heart Failure
Interventions: DRUG: Ferinject (ferric carboxymaltose)|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Everolimus in Combination With Cyclosporine Microemulsion Versus Everolimus in Combination With Enteric-coated Mycophenolate Sodium (EC-MPS), in Adult Renal Transplant Patients in Maintenance.
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Everolimus + Cyclosporine|DRUG: Everolimus + Enteric-coated Mycophenolate Sodium (EC-MPS)|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Early Achievements- Parent Coaching Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso
Status: COMPLETED
Conditions: Multiple Micronutrient Deficiencies During Pregnancy
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrient supplements (MMN)|DIETARY_SUPPLEMENT: IFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study in Children to Evaluate Non-Inferiority and Persistence up to 5 Years of GSK Bio Meningococcal Vaccine 134612
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: GSK Biolgicals' meningococcal vaccine 134612 (Nimenrix)|BIOLOGICAL: Mencevax™ ACWY|BIOLOGICAL: Meningitec™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Technique Interpectoral Catheter for Postoperative Analgesia in Modified Radical Mastectomy
Status: COMPLETED
Conditions: Mammary Cancer
Interventions: DEVICE: catheter|DRUG: iv analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors
Status: RECRUITING
Conditions: High Grade Glioma|Meningioma|Embryonal Tumor|Medulloblastoma|Anaplastic Ependymoma|Recurrent Diffuse Intrinsic Pontine Glioma|Recurrent Malignant Glioma|Recurrent Medulloblastoma|Recurrent Primary Central Nervous System Neoplasm|Refractory Diffuse Intrinsic Pontine Glioma|Refractory Malignant Glioma|Refractory Medulloblastoma|Refractory Primary Central Nervous System Neoplasm
Interventions: DRUG: LUTATHERA® (Lutetium Lu 177 dotatate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oxytocin on Reinforcement Learning and Interoception
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Intranasal oxytocin|DRUG: intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Perioperative Analgesic Modalities for Breast Cancer Surgeries
Status: COMPLETED
Conditions: Analgesia
Interventions: PROCEDURE: serratus plane block|PROCEDURE: erector spinae block|DRUG: Morphine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Regulation of Blood Dendritic Cells During Immune Therapy for Hymenoptera Venom Allergy
Status: UNKNOWN
Conditions: Hymenoptera Venom Allergy
Interventions: BIOLOGICAL: Hymenoptera venom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Acetazolamide on Right Ventricular Function at Rest in Patients With Respiratory Disease at Altitude
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: ACETAZOLAMIDE oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy
Status: RECRUITING
Conditions: Prostate Adenocarcinoma|Stage IIIB Prostate Cancer American Joint Committee on Cancer (AJCC) v8|Stage IIIC Prostate Cancer AJCC v8|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Hormone Therapy|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurocognitive Deficit|Mental Health Impairment|Neurofibromatosis 1
Interventions: BEHAVIORAL: OPTIMAL-SSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
Status: COMPLETED
Conditions: Bundle-Branch Block|Heart Septal Defects, Ventricular
Interventions: PROCEDURE: Echocardiography at rest|PROCEDURE: Echocardiography during exercise|PROCEDURE: MRI at rest|PROCEDURE: Exercise testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: ECG for Programming in CRT
Status: TERMINATED
Conditions: Systolic Heart Failure|Cardiac Resynchronization Therapy|Electrocardiography
Interventions: DEVICE: Programming individualized RV-LV pacing offset to optimize ECG|DEVICE: Nominally programming CRT device without RV-LV offset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Active Implementation of a Guideline for Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Implementation of a Chronic Disease Management Programme|COPD
Interventions: OTHER: Active implementation of a guideline for chronic disease
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Endometrial Carcinoma|Recurrent Endometrial Endometrioid Adenocarcinoma|Refractory Endometrial Carcinoma|Refractory Endometrial Endometrioid Adenocarcinoma|Stage III Uterine Corpus Cancer AJCC v8|Stage IIIA Uterine Corpus Cancer AJCC v8|Stage IIIB Uterine Corpus Cancer AJCC v8|Stage IIIC Uterine Corpus Cancer AJCC v8|Stage IIIC1 Uterine Corpus Cancer AJCC v8|Stage IIIC2 Uterine Corpus Cancer AJCC v8|Stage IV Uterine Corpus Cancer AJCC v8|Stage IVA Uterine Corpus Cancer AJCC v8|Stage IVB Uterine Corpus Cancer AJCC v8
Interventions: DRUG: Everolimus|DRUG: Letrozole|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tiotropium Inhalation Capsules on Exercise Tolerance, Daily Activity and Dyspnoea in Patients With Chronic Obstructive Pulmonary Disease (COPD) Participating in 3 Weeks of Pulmonary Rehabilitation
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium Inhalation Capsule|DRUG: Placebo Lactose Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Confocal Laser Endomicroscopy With Cresyl Violet for in Vivo Diagnosis of Gastric Intestinal Metaplasia
Status: COMPLETED
Conditions: Gastric Intestinal Metaplasia
Interventions: DIAGNOSTIC_TEST: Cresyl violet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Adding Renin-Angiotensin System Inhibitors to Standard Antidiabetic Therapy on Glycemic Control in Patients With Type 2 Diabetes Ellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Valsartan 80 mg and metformin|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Acute Myeloid Leukemia (AML)|Untreated AML|AML Arising From Myelodysplastic Syndrome (MDS)|AML Arising From Antecedent Hematologic Disorder (AHD)|AML Arising After Exposure to Genotoxic Injury
Interventions: DRUG: AG-120|DRUG: AG-221|DRUG: cytarabine|DRUG: daunorubicin|DRUG: idarubicin|DRUG: mitoxantrone|DRUG: etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of TBI-1401(HF10) Plus Chemotherapy in Patients With Unresectable Pancreatic Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer Stage III|Pancreatic Cancer Stage IV
Interventions: BIOLOGICAL: TBI-1401(HF10)|DRUG: Gemcitabine|DRUG: Nab-paclitaxel|DRUG: TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet Quality, Pecans, and Cardiometabolic Health
Status: WITHDRAWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: Pecan|OTHER: Average American Diet devoid of nuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Peer Support in Improving Heart Failure Self-Management and Care
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: BEHAVIORAL: Interactive Voice Response System|BEHAVIORAL: Nurse-Led Group Clinic Visits
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study on Oral Nemonoxacin Malate Capsules
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Nemonoxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NF135 CPS Immunization
Status: TERMINATED
Conditions: Malaria,Falciparum|Controlled Human Malaria Infection|Immunization; Infection
Interventions: BIOLOGICAL: CPS-immunization|BIOLOGICAL: malaria challenge infection, P. falciparum NF135.C10|BIOLOGICAL: malaria challenge infection, P. falciparum NF54|BIOLOGICAL: CPS-immunization (A/L)|DRUG: Atovaquone / Proguanil Oral Tablet [Malarone]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: REWRITALIZE Your Recovery - Evaluation of a Creative Writing Group Intervention
Status: ENROLLING_BY_INVITATION
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders
Interventions: OTHER: Rewritalize|OTHER: Standard mental health care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The D-KAF (Dalteparin in Knee-to-Ankle Fracture) Trial
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: Low Molecular Weight Heparin (dalteparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Cholangiocarcinoma
Status: UNKNOWN
Conditions: Advanced Cholangiocarcinoma
Interventions: DRUG: Anlotinib|DRUG: TQB2450
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sulodexide in Early Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Sulodexide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Bovine Basic Fibroblast Growth Factor for the Treatment of Radiation Induced Oral Mucositis
Status: UNKNOWN
Conditions: Stomatitis
Interventions: DRUG: Recombinant bovine basic fibroblast growth factor|COMBINATION_PRODUCT: Quadruple mixture, composed of dexamethasone, gentamicin, vitamin B12, and lidocaine composition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discontinuation of Long-term Medications in Older People Entering Nursing Home Care
Status: UNKNOWN
Conditions: Polypharmacy|Frail Elderly Syndrome|Inappropriate Prescribing|Drug-Related Side Effects and Adverse Reactions
Interventions: OTHER: STOPPFrail deprescribing criteria
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resistant Starch Supplementation Effects on the Intestinal Tract Profile and Cardiovascular Markers in Renal Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease|Hemodialysis|Non-dialysis Patients
Interventions: DIETARY_SUPPLEMENT: 'resistance starch for CKD|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Effectiveness of Tecfidera (Dimethyl Fumarate) on Multiple Sclerosis (MS) Disease Activity and Patient-Reported Outcomes
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Multiple Sclerosis
Interventions: DRUG: dimethyl fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery
Status: SUSPENDED
Conditions: Breast Carcinoma|Colon Carcinoma|Invasive Carcinoma|Kidney Carcinoma|Liver Carcinoma|Malignant Solid Neoplasm|Multiple Myeloma|Prostate Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Terlipressin When Usual Somatostatin or Octreotide Dose Fails
Status: UNKNOWN
Conditions: Liver Cirrhosis|Esophageal and Gastric Varices|Hemorrhage
Interventions: DRUG: Terlipressin|DRUG: Usual Dose Somatostatin/Octreotide|DRUG: High Dose Somatostatin/Octreotide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease
Status: TERMINATED
Conditions: Coronary Heart Disease|Chlamydophila Pneumoniae Infections
Interventions: DRUG: Doxycycline Capsule|DRUG: Azithromycin Capsule|DRUG: Rifabutin Oral Capsule|DRUG: Placebo oral capsule|DRUG: Placebo Oral Tablet|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Volumes of Local Anesthetics in Thoracolumbar Interfascial Plane Block
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Thoracolumbar interfascial plane block (TLIP)Technique|PROCEDURE: Anesthetic Management|DRUG: Bupivacaine Injection 10ml|DRUG: Bupivacaine Injection 20ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: PEG-Tα1|DRUG: Placebo to match PEG-Tα1|DRUG: Adefovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Functionnal ElectromyoStimulation on Leg In Advanced Chronic Heart Failure After Hospitalisation for Acute Decompensation
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: OTHER: Functionnal ElectroStimulation (FES)|OTHER: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single-dose Safety Study of APD916 in Healthy Volunteers
Status: COMPLETED
Conditions: Narcolepsy With or Without Cataplexy
Interventions: DRUG: APD916
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Long-Term Treatment Study, to Assess the Long-Term Safety and Tolerability and Efficacy of Neramexane in Patients With Subjective Tinnitus
Status: TERMINATED
Conditions: Subjective Tinnitus
Interventions: DRUG: Neramexane mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Constraint-induced Movement Therapy and Self-regulation for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: mCIMT + SR|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer
Status: COMPLETED
Conditions: Peritoneal Cancer|Ovarian Cancer|Neoplasms, Ovarian|Fallopian Tube Cancer
Interventions: DRUG: Topotecan|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Gabapentin group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Versus Laparoscopic Right Hemicolectomy for Right Colon Cancer
Status: COMPLETED
Conditions: Colonic Cancer
Interventions: PROCEDURE: laparoscopic right hemicolectomy with CME and central v|PROCEDURE: Open right hemicolectomy with CME and central v
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Healthy and Affordable Protein Rich Foods for African Market
Status: COMPLETED
Conditions: School Feeding Programs and Nutrition Supplements
Interventions: DIETARY_SUPPLEMENT: protein powder supplement|DIETARY_SUPPLEMENT: Vitamins/minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study of Levocetirizine Dihydrochloride Oral Liquid Formulation in Children Aged 6 Months to 11 Months
Status: COMPLETED
Conditions: Allergic Rhinitis|Chronic Urticaria
Interventions: DRUG: Levocetirizine 1.25 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of SMT C1100 in Subjects With Duchenne Muscular Dystrophy (DMD)
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: SMT C1100
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacodynamic and Pharmacokinetic Effects of LX4211 in Subjects With Type 2 Diabetes and Renal Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Renal Impairment
Interventions: DRUG: LX4211|DRUG: LX4211 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iranian Intensive Care Unit (ICU) Glutamine Study
Status: COMPLETED
Conditions: Trauma Patients in ICU
Interventions: DIETARY_SUPPLEMENT: Glutamine 0.5 g/kg/day|DIETARY_SUPPLEMENT: Glutamine 1 g/kg/day|DIETARY_SUPPLEMENT: Enteral Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Retrieval of Hepatitis C Patients Lost to Follow-up
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: BEHAVIORAL: Retrieval patients lost to follow-up with positive HCV antibodies without RNA request or positive RNA by phone call.|BEHAVIORAL: Retrieval patients lost to follow-up with positive HCV antibodies without RNA request or positive RNA by mail letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation and Neurorehabilitation for mTBI Plus PTSD
Status: UNKNOWN
Conditions: Mild Traumatic Brain Injury|Post Traumatic Stress Disorder
Interventions: DEVICE: real iTBS|BEHAVIORAL: real APT|BEHAVIORAL: placebo APT|DEVICE: placebo iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of M5049 in CLE and SLE Participants
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Cutaneous Lupus Erythematosus
Interventions: DRUG: M5049|DRUG: M5049|DRUG: M5049|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spiriva (Tiotropium Bromide) Assessment of FEV1 - (SAFE-Portugal).
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Pulmonary function Testing|DRUG: tiotropium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Trial of a Botanical Drug (EISO) for Treatment of Mild-to-Moderate Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: SAN021 Serum|DRUG: SAN021 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UC-MSCs in the Treatment of Severe and Critical COVID-19 Patients With Refractory Hypoxia
Status: RECRUITING
Conditions: Mesenchymal Stem Cell|COVID-19 Pneumonia
Interventions: BIOLOGICAL: UC-MSCs treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection
Status: UNKNOWN
Conditions: Leukemia|Transplantation, Hematopoietic Stem Cell
Interventions: DRUG: Caspofugin based combination therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NHF vs. COT in Hypoxemic Pandemic Viral Illness
Status: UNKNOWN
Conditions: Acute Viral Bronchitis|Hypoxemic Respiratory Failure|Hypercapnic Respiratory Failure
Interventions: DEVICE: Standard oxygen|DEVICE: Nasal high-flow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Social Accountability on Improving Service Delivery and Outcomes in the Public Sector in Uttar Pradesh, India
Status: COMPLETED
Conditions: Health Behavior
Interventions: OTHER: Information Only|OTHER: Information and Facilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: To Determine How Different Doses of Tadalafil Work on Getting and Keeping an Erection 26 or 36 Hours After Taking
Status: COMPLETED
Conditions: Impotence
Interventions: DRUG: tadalafil|DRUG: placebo|DRUG: tadalafil|DRUG: tadalafil|DRUG: tadalafil|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transient Elastography in the Determination of Advanced Fibrosis in Alcoholic Liver Disease.
Status: COMPLETED
Conditions: Alcoholism|Liver Disease|Liver Fibrosis
Interventions: OTHER: Determination of Advanced Fibrosis in Alcoholic Liver Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment Persistence Among Patients With Overactive Bladder: A Retrospective Secondary Data Analysis in Asia Oceania
Status: COMPLETED
Conditions: Overactive Bladder (OAB)
Interventions: DRUG: mirabegron|DRUG: solifenacin|DRUG: darifenacin|DRUG: imidafenacin|DRUG: tolterodine|DRUG: oxybutynin|DRUG: trospium|DRUG: fesoterodine|DRUG: propiverine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial Comparing Gemcitabine and Vandetanib Therapy With Gemcitabine Alone in Pancreatic Carcinoma
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Placebo|DRUG: Caprelsa (vandetanib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 3D High Resolution Anorectal Manometry in Children After Surgery for Anorectal Disorders
Status: COMPLETED
Conditions: Children|Anorectal Disorder|Anorectal Atresia|Hirschsprung Disease
Interventions: DEVICE: 3D high resolution anorectal manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of RO5503781 as a Single Agent or in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia
Status: COMPLETED
Conditions: Myelogenous Leukemia, Acute
Interventions: DRUG: RO5503781 MBP|DRUG: RO5503781 SDP|DRUG: Idarubicin|DRUG: Daunorubicin|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG-ASP, Etoposide and Gemcitabine for Natural Killer/T Lymphoma
Status: RECRUITING
Conditions: Treatment Refusal
Interventions: DRUG: Gemcitabine|DRUG: etoposide|DRUG: Pegaspargase|RADIATION: involved-field radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Intervention in Insulin Resistance Targeting Autonomic Nerve Activity
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: Atropine|DRUG: Physostigmine|DRUG: Placebo Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PIvotal Trial of the KARDION Cory P4 MechANical Circulatory SupporT SystEm
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous Mechanical Circulatory Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT