pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multicentre, Prospective, Non-interventional Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extra-fine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related Outcomes
Status: RECRUITING
Conditions: ASTHMA
Interventions: OTHER: Non-interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Colectomy in Patients With Asymptomatic and Unresectable Stage IV Colon Cancer
Status: UNKNOWN
Conditions: Malignant Neoplasm of Large Intestine|Colon Cancer Liver Metastasis
Interventions: PROCEDURE: Colectomy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Decitabine Induction Prior to Allogeneic Hematopoietic Cell Transplant in Newly Diagnosed MDS Patients
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LARA: Use of JACO2 Controlled by Joystick or by Voice Control System, in Muscular Dystrophy
Status: COMPLETED
Conditions: Muscular Dystrophies
Interventions: DEVICE: JACO2|DEVICE: VOCAL CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rate-limiting Amino Acids in Endurance-trained Athlete
Status: COMPLETED
Conditions: Increased Metabolic Requirement|Healthy
Interventions: DIETARY_SUPPLEMENT: Base protein|DIETARY_SUPPLEMENT: Sufficient protein|DIETARY_SUPPLEMENT: Branched chain amino acids|DIETARY_SUPPLEMENT: Essential amino acids|DIETARY_SUPPLEMENT: Non essential amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Anti-angiogenic Therapy for Telangiectasia in HHT: Proof of Concept
Status: COMPLETED
Conditions: Hereditary Hemorrhagic Telangiectasia
Interventions: DRUG: Topical timolol maleate|DRUG: placebo saline drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Levofloxacin Compared With Ceftriaxone Sodium or Cefuroxime Axetil in the Treatment of Adults With Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Possible Efficacy and Safety of L-carnitine and Biotin as Adjunctive Therapies in Children With Moderate Persistent Asthma
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate Persistent Asthma
Interventions: DRUG: Placebo|DRUG: L-Carnitine 500Mg Oral Tablet|DRUG: Biotin Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Assisted Lumbar Puncture in the Neonate
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Puncture
Interventions: OTHER: Palpation Landmark Technique|DEVICE: Ultrasound-Assisted Technique LP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long-Term Safety Study of Canagliflozin (TA-7284) in Combination With GLP-1 Analogue in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Canagliflozin (TA-7284)|DRUG: GLP-1 analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Postoperative Radiotherapy in N1 Breast Cancer Patients
Status: RECRUITING
Conditions: Radiotherapy|Breast Cancer
Interventions: RADIATION: No PMRT for mastectomy / No regional RT for BCS|RADIATION: PMRT for mastectomy / WBI + Regional RT for BCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dosing Study of Ranibizumab for Diabetic Retinal and Macular Edema
Status: COMPLETED
Conditions: Diabetic Retinopathy|Macular Edema
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-labeled Phase II Study to Evaluate the Efficacy and Safety of GXNPC-1 in Patients With Chronic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Stroke
Interventions: DRUG: GXNPC1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacological Manipulation of Intrahepatic Arterial Blood Flow in HCC
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: CT perfusion|DRUG: Norepinephrine intra-arteriel/hepatic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized CO2 vs Sham Laser Treatment of Provoked Vestibulodynia
Status: WITHDRAWN
Conditions: Vestibulodynia
Interventions: DEVICE: Fractional CO2 Laser Treatment|DEVICE: Sham Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Tolerability of Two Formulations of Hypertonic Saline in Cystic Fibrosis Patients
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: OTHER: Inhalable Hypertonic saline 7% + Hyaluronan 0.1%|OTHER: Inhalable Hypertonic saline 7%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Trial to Assess Vagus Nerve Stimulation Therapy in Children With Lennox-Gastaut Syndrome
Status: UNKNOWN
Conditions: Lennox-Gastaut Syndrome
Interventions: DEVICE: PINS Vagus Nerve Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin E Dosing Study
Status: RECRUITING
Conditions: Nonalcoholic Fatty Liver Disease|Nonalcoholic Steatohepatitis
Interventions: DRUG: Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AZD4205 and carbamazepine|DRUG: AZD4205 and itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computerised Working Memory Training in Acquired Brain Injury
Status: UNKNOWN
Conditions: Acquired Brain Injury
Interventions: DEVICE: Active tDCS|DEVICE: SHAM tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Apoptosis Proteins and Endothelial Dysfunction in Patients With Atherosclerosis of Peripheral Arteries
Status: COMPLETED
Conditions: Atherosclerosis|Endothelial Dysfunction
Interventions: PROCEDURE: Bypass surgery|PROCEDURE: Endovascular angioplasty/stenting|PROCEDURE: Hybrid surgery|DRUG: Vitamin E|DIAGNOSTIC_TEST: Duplex ultrasound|DIAGNOSTIC_TEST: Blood sampling|DIAGNOSTIC_TEST: Arterial wall sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and Paraganglioma
Status: WITHDRAWN
Conditions: Phaeochromocytoma|Paraganglioma
Interventions: DRUG: Vandetanib|RADIATION: 131I-mIBG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retreatment and Its Efficiency of Thalidomide for Vascular Malformation Patients With Failure of First Course Treatment
Status: WITHDRAWN
Conditions: Gastrointestinal Bleeding of Unknown Origin|Gastrointestinal Vascular Malformation|Thalidomide Efficiency
Interventions: DRUG: Thalidomide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Efficacy Trial of Z160 in Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Lumbosacral Radiculopathy
Interventions: DRUG: z160|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: AML
Interventions: DRUG: Cytarabine|DRUG: all-trans retinoic acid|DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Cirrhosis-related Hepatocellular Carcinoma With the Intrahepatic Arterial Injection of an Emulsion of Lipiodol and Idarubicin (Zavedos®): Phase I Study
Status: COMPLETED
Conditions: Unresectable Non-metastatic Hepatocellular Carcinoma|Child A/B7 Cirrhosis
Interventions: DRUG: Zavedos®|OTHER: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose:
Clinical trial: Extension Study of IONIS-GHR-LRx Administered to Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: IONIS GHR-LRx|DRUG: Somatostatin Receptor Ligand (SRL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropathic Pain in Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: OTHER: painDETECT questionnaire|OTHER: Douleur Neuropathique 4 questionnaire (DN4)|OTHER: Short form-36|OTHER: Spondyloarthritis Research Consortium of Canada Enthesitis Index (SPARCC)|OTHER: Numeric Rating Scale|OTHER: Disease activity in psoriatic arthritis (DAPSA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Building and Pilot Testing a Couples-based Smartphone Systems to Address Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Couples|Behavior, Addictive
Interventions: BEHAVIORAL: PartnerCHESS|BEHAVIORAL: A-CHESS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Eplerenone, Aflibercept and Topical Nepafenac Serous Foveal Deta Chment in Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: OTHER: Eplerenone , Intravitreal Aflibercept and Topical nepafenac therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Greenselect Phytosome® on Weight Maintenance After Weight Loss in Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Globes®|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: RTS,S with AS02A/AS01B adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: 68Ga-DOTA-TOC PET/CT in Imaging Participants With Neuroendocrine Tumors
Status: TERMINATED
Conditions: Meningioma|Metastatic Well Differentiated Neuroendocrine Neoplasm|Multiple Endocrine Neoplasia Type 1|Neuroendocrine Neoplasm|Somatostatin Positive Neoplastic Cells Present|Von Hippel-Lindau Syndrome
Interventions: PROCEDURE: Computed Tomography|DRUG: Gallium Ga 68-Edotreotide|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Intra-dermal Injection of Botulinum Toxin Type A for the Diabetic Neuropathic Foot Pain
Status: COMPLETED
Conditions: Diabetes Mellitus|Neuropathic Pain
Interventions: DRUG: Botulinum Toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Chantix on Relapse Prevention for Smoking Cessation
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Placebo|DRUG: Varenicline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS People
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Spinal Cord Diseases|Alternative Communication Devices|Neurodegenerative Diseases|Nervous System Diseases|Neuromuscular Diseases
Interventions: DEVICE: New headset prototype
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea
Status: UNKNOWN
Conditions: Seborrhea|Seborrheic Dermatitis|Quality of Life
Interventions: DRUG: oral isotretinoin|DRUG: salicylic acid and ciclopirox olamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OTIS - Optimized Complementary Feeding Study
Status: COMPLETED
Conditions: Infant Development|Body Composition, Beneficial|Dietary Modification
Interventions: OTHER: Systematic introduction of taste portions|OTHER: Protein reduced complementary foods|OTHER: Nordic diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy of Prasinezumab (RO7046015/PRX002) in Participants With Early Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson's Disease
Interventions: DRUG: RO7046015|DRUG: RO7046015|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Light Therapy Treatment in Parkinson's Disease Patients With Daytime Somnolence
Status: COMPLETED
Conditions: Parkinson's Disease|Sleep Disorder; Excessive Somnolence
Interventions: DEVICE: Bright Light Treatment (Sun Ray Sunbox SB-558)|DEVICE: Dim red light (Sun Ray Sunbox SB-558)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Fingolimod (Gilenya) 0.5 mg in Chinese Patients With Relapsing Multiple Sclerosis (RMS) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis (RMS)
Interventions: DRUG: Fingolimod 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
Status: RECRUITING
Conditions: Venous Thromboembolism|Deep Venous Thrombosis|Pulmonary Embolism
Interventions: BIOLOGICAL: Abelacimab|DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: dMAbs for Prevention of COVID-19
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: COMBINATION_PRODUCT: dMAb AZD5396|COMBINATION_PRODUCT: dMAb AZD8076|COMBINATION_PRODUCT: CELLECTRA™ 2000 with Side Port needle, OpBlock 0078 Electroporation device|DRUG: Hylenex|COMBINATION_PRODUCT: CELLECTRA™ 2000 with Side Port needle, OpBlock 0070 Electroporation device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Pimecrolimus cream|DRUG: Betamethasone dipropionate cream|DRUG: Clobetasol propionate cream|DRUG: Glaxal Base cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Data Acquisition and Image Characteristics of Brain Multifrequency EIT in Healthy People and Patients With Brain Diseases
Status: COMPLETED
Conditions: Cerebral Hemorrhage|Cerebral Ischemia|Cerebral Edema|Healthy
Interventions: DIAGNOSTIC_TEST: multifrequency EIT-based for detecting intracranial abnormalities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adaptive Radiotherapy in Patients With Gynecological Tumors
Status: RECRUITING
Conditions: Gynecological Tumor|Adaptive Radiotherapy|Radiation|Curative Treatment|Optimization|Adaptive Radiation Therapy|Image Guided Radiotherapy|Cervical Carcinoma
Interventions: RADIATION: Adaptive Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Families Talking Together Plus: An Approach to Promote Sexual Delay and Strengthen Sexual Risk Avoidance Education
Status: ACTIVE_NOT_RECRUITING
Conditions: Behavior and Behavior Mechanisms
Interventions: BEHAVIORAL: Families Talking Together Plus (FTT +)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Topical Versus Systemic Treatment in Postherpetic Neuralgia and Diabetic Polyneuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: Topical analgesic|DRUG: oral intake|DRUG: Topical analgesic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Economic Purchasing Decisions for Cigarettes of Varied Compositions
Status: COMPLETED
Conditions: Tobacco Use Disorder|Substance-Related Disorders
Interventions: OTHER: Altered composition cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Pegcetacoplan|DRUG: Soliris
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ColdZyme® Mouth Spray on Prevention and Alleviation of Rhinovirus Induced Common Cold
Status: COMPLETED
Conditions: Common Cold
Interventions: DEVICE: ColdZyme® mouth spray|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26)
Status: RECRUITING
Conditions: Leptomeningeal Disease
Interventions: DRUG: Nivolumab [Opdivo]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Novel Positioning Sensor-assisted Postoperative Position Correction and Effective Prone Time Recorded in Patients With Different Prone Times After Macular Hole Surgery
Status: RECRUITING
Conditions: Idiopathic Macular Hole|Effective Prone Time
Interventions: BEHAVIORAL: Face-down position time 1-day|BEHAVIORAL: Face-down position time 3-day
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lactobacillus Vaginalis Capsules for Treatment of Vulvovaginal Atrophy in Young Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: DRUG: Vaginal Lactobacillus capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of a Single Infusion of VAY736 on Disease Activity in Patients With Relapsing-remitting Multiple Sclerosis
Status: TERMINATED
Conditions: Relapse Remitting Multiple Sclerosis
Interventions: DRUG: VAY736|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade
Status: UNKNOWN
Conditions: Interscalene Block|Shoulder Arthroscopy|Dexamethasone|Low Volume Regional Anesthesia
Interventions: DRUG: Dexamethasone acetate|DRUG: Placebo|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Oral Venetoclax Tablets in Combination With Subcutaneously (SC) or Intravenously (IV) Injected Azacitidine in Colombia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Epalrestat on Peripheral Neuropathy and Central Nervous System in Diabetic Patients
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: Epalrestat,Mecobalamin|DRUG: Mecobalamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Therapeutic Exercise With Elastic Bands on Strength and Pain in Women With Non-specific Neck Pain.
Status: COMPLETED
Conditions: Neck Pain|Exercise Therapy|Women
Interventions: BEHAVIORAL: Therapeutic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 12-week Milk Fat Globule Membrane Supplementation on the Human Muscle Function of Middle-aged Exercisers
Status: NOT_YET_RECRUITING
Conditions: Ageing Well|Age-Related Atrophy|Age-Related Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Bioactive whey protein concentrate|DIETARY_SUPPLEMENT: Pea-based protein supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 Clinical Trial to Evaluate the Safety of Allogeneic NK Cell ("SMT-NK") Cell Therapy in Advanced Biliary Tract Cancer
Status: COMPLETED
Conditions: Advanced Biliary Tract Cancer
Interventions: BIOLOGICAL: Natural killer cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effectiveness and Safety of SugarDown vs. Placebo in Type 2 Diabetic Subjects Treated With Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: SugarDown|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Shenzhen Quadrivalent Inactivated Influenza Vaccine Versus the Shenzhen Trivalent Inactivated Influenza Vaccine in Chinese Subjects From 6 Months of Age
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine|BIOLOGICAL: Trivalent Influenza Vaccine 1 SP Shz TIV1|BIOLOGICAL: Trivalent Influenza Vaccine 2 SP Shz TIV2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stroke Adverse Outcome is Associated With Nosocomial Infections: PCTus- Guided Antibacterial Therapy in Severe Ischemic Stroke Patients (STRAWINSKI)
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: Procalcitonin assay - B.R.A.H.M.S PCT ultrasensitive Kryptor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Resistance Intervention After Stroke Trial
Status: COMPLETED
Conditions: Stroke|Myocardial Infarction|Diabetes
Interventions: DRUG: pioglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patency-Coronary Trial
Status: UNKNOWN
Conditions: Complications Due to Coronary Artery Bypass Graft|Graft Failure
Interventions: PROCEDURE: On-pump CABG|PROCEDURE: Off-pump CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Helicobacter Pylori Eradication in Non-diabetic Non-alcoholic Steatohepatitis
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DRUG: H.pylori eradication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph3 Safety/Efficacy Study of Rolapitant for the Prevention of CINV in Subjects Receiving Highly Emetogenic Chemotherapy
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Rolapitant|DRUG: Granisetron|DRUG: dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: No Direct Patient Outreach|BEHAVIORAL: Direct Patient Outreach: Colonoscopy Only|BEHAVIORAL: Direct Patient Outreach: Sequential Choice|BEHAVIORAL: Visit-Based Nudge/Text|BEHAVIORAL: No Nudge/Text
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Safety and Antitumor Activity in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Advanced Recurrent Ovarian Tumors
Interventions: DRUG: MEDI3617|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aromatherapy Effect on Pain and Anxiety After C-section
Status: COMPLETED
Conditions: Post-operative Pain|Post-operative Anxiety
Interventions: OTHER: Aromatherapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Into Pain Relief Given by ASP8477 for Peripheral Neuropathic Pain (Either Post-herpetic Neuralgia or Painful Diabetic Peripheral Neuropathy) and Its Safety
Status: COMPLETED
Conditions: Post-Herpetic Neuralgia (PHN)|Neuropathic Pain|Painful Diabetic Peripheral Neuropathy (PDPN)
Interventions: DRUG: ASP8477|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer
Status: UNKNOWN
Conditions: Solid Tumor|Metastatic Cancer
Interventions: DRUG: TJ004309|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Type 2 Diabetes Mellitus by L-Arginine in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Impaired Glucose Tolerance|Insulin Resistance|Endothelial Dysfunction
Interventions: DRUG: L-arginine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Cluster Controlled Trial Comparing Three Methods of Disseminating Practice Guidelines for Children With Croup
Status: TERMINATED
Conditions: Croup
Interventions: BEHAVIORAL: mailing of printed educational materials|BEHAVIORAL: a combination of interactive educational meetings, educational outreach visits, and reminders|BEHAVIORAL: identification of local opinion leaders and establishment of local consensus processes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: ECT
Clinical trial: Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery
Status: NOT_YET_RECRUITING
Conditions: Older Patients|Cognitive Impairment|Repetitive Transcranial Magnetic Stimulation|Delayed Neurocognitive Recovery|Postoperative Neurocognitive Disorder
Interventions: DEVICE: Repetitive transcranial magnetic stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Breast Cancer Screening Uptake: a Randomized Controlled Trial Assessing the Effect of a Decisional Aid
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Leaflet "decidons ensemble" (making a decision together)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Customized Neoadjuvant Versus Standard Chemotherapy in NSCL Patients With Resectable Stage IIIA (N2)Disease
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Cisplatin Docetaxel Gefitinib Pemetrexed Vinorelbine Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of Two Tecnis Investigational Lenses
Status: COMPLETED
Conditions: Cataract|Corneal Astigmatism
Interventions: DEVICE: Investigational IOL Model C1V000|DEVICE: Investigational IOL Model C2V000|DEVICE: Control IOL Model ICB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: Adenosine Triphosphate|DRUG: Capsaicin|OTHER: Functional Brain Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cognitive-Behavioral Therapy and Escitalopram for Generalized Anxiety Disorder(GAD)
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy|DRUG: escitalopram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2)
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: ianalumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals
Status: TERMINATED
Conditions: Cocaine Abuse|Cocaine-Related Disorders
Interventions: DRUG: GBR 12909|DRUG: GBR 12909|DRUG: GBR 12909
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Protection and Promotion of Sign Language Interpreters Through Implementation of Total Worker Health®
Status: NOT_YET_RECRUITING
Conditions: Well-Being, Psychological
Interventions: BEHAVIORAL: Health Protection and Promotion|BEHAVIORAL: General Health Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.
Status: RECRUITING
Conditions: Myocardial Infarction|ST-Elevation Myocardial Infarction (STEMI)|Reperfusion Injury|Microvascular Occlusion
Interventions: PROCEDURE: Intracoronary hypothermia|OTHER: Standard percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study Of Adding Bortezomib to R-ICE Chemotherapy To Treat Relapsed/ Refractory Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Diffuse Large B-Cell Lymphoma
Interventions: DRUG: bortezomib, rituximab, ifosphamide, etoposide, carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults
Status: COMPLETED
Conditions: Muscle Atrophy|Quality of Life
Interventions: DRUG: Essential Amino Acids (EAA)|DRUG: Placebo (Alanine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Moderately Hypofractionated Conformal Radiation Combined With S-1 for Esophageal Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: Moderately hypofractionated conformal radiation combined With S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease
Status: RECRUITING
Conditions: Psychosis Associated With Alzheimer's Disease
Interventions: DRUG: KarXT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety of Foralumab, an Oral Anti-CD3 Antibody, in Patients With NASH and T2DM
Status: WITHDRAWN
Conditions: NASH - Nonalcoholic Steatohepatitis|NAFLD|T2DM (Type 2 Diabetes Mellitus)
Interventions: DRUG: Foralumab|OTHER: placebo|DRUG: Omeprazole 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: COMorbidities and EDucation in SPondyloArthritis Study
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BEHAVIORAL: self-assessment/self-management|BEHAVIORAL: Comorbidities (detection/prevention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Three Licensed Influenza Vaccines
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: FluBlok|BIOLOGICAL: Fluzone|BIOLOGICAL: FluCelVax|BIOLOGICAL: Fluzone HD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of the Tuberculin Skin Test (TST) and QuantiFERON ®-TB Gold Test (QFT-G) In Patients With Rheumatoid Arthritis Being Considered for Anti-TNF-Alpha Therapy
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Tuberculosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Unilateral Laparoscopic Diathermy Adjusted to Ovarian Volume
Status: COMPLETED
Conditions: PCOS
Interventions: PROCEDURE: Unilateral laparoscopic drilling|PROCEDURE: Bilateral laparoscopic drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation
Status: COMPLETED
Conditions: Hematologic Malignancies|Nonmalignant Diseases|Immunodeficiencies|Hemoglobinopathies|Genetic Inborn Errors of Metabolism|Fanconi Anemia|Thalassemia|Sickle Cell Disease
Interventions: DRUG: Fludarabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single Strain Probiotic
Status: RECRUITING
Conditions: Abdominal Obesity
Interventions: DIETARY_SUPPLEMENT: Single strain probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Silodosin to Facilitate Passage of Urinary Stones
Status: COMPLETED
Conditions: Ureteral Calculi|Kidney Stones|Urolithiasis
Interventions: DRUG: silodosin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Busulfan Concentration in Saliva and Plasma, and Its Relationship With Salivary Changes and Mucositis in the Digestive Tract of Patients Submitted to Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Bone Marrow Disease
Interventions: DIAGNOSTIC_TEST: Saliva monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutrient Timing Following Resistance Exercise
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Immediate Nutrition|DIETARY_SUPPLEMENT: Nutrition 3 hours Post-Bout|OTHER: Resistance Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients
Status: COMPLETED
Conditions: HIV Seropositivity
Interventions: DRUG: CBD LGP 50|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Carcinoma|Head and Neck Lymph Node|Head and Neck Squamous Cell Carcinoma|Laryngeal Neoplasm|Radiation Therapy Recipient
Interventions: PROCEDURE: Photoacoustic Imaging|PROCEDURE: Transcutaneous Acupoint Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-CRN00808|DRUG: CRN00808
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study Evaluating Different Dosing Regimens of Rabeprazole in Gastro-esophageal Reflux Disease (GERD) Patients With Night-time Heartburn Symptoms.
Status: COMPLETED
Conditions: Gastroesophageal Reflux|Heartburn
Interventions: DRUG: rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healing of Post-ext Sites Using Bovine Bone Mineral: a CBCT and Histologic RCCT
Status: COMPLETED
Conditions: Loss of Teeth Due to Extraction|Edentulous Alveolar Ridge
Interventions: PROCEDURE: Ridge Augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Appetite Related Hormones in Binge Eating Behaviour Among the Overweight and Obese
Status: COMPLETED
Conditions: Binge Eating Behaviour
Interventions: DRUG: Liraglutide|BEHAVIORAL: Diet and Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Omega-3 Fatty Acids on Oxidative Stress and Dyslipidemia in Pediatric Patients Undergoing Hemodialysis
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: omega-3|OTHER: empty soft gelatin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Peripheral Vascular Disease|Peripheral Artery Occlusive Disease|Peripheral Artery Disease
Interventions: OTHER: LEAP therapy|OTHER: no LEAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DA5221-T When Added to Ongoing DA5221-B1 and DA5221-B2 Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: DA5221-T1|DRUG: DA5221-T2|DRUG: Placebo|DRUG: DA5221-B1|DRUG: DA5221-B2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Litramine in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Overweight|Obesity|Weight Loss
Interventions: DEVICE: Litramine|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery
Status: RECRUITING
Conditions: Elderly|Hip Fracture Surgery|Patient-controlled Analgesia|Dexmedetomidine|Postoperative Delirium
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined Intravenous Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Orthopaedic Surgery of the Foot and Ankle
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Saline|DRUG: Dexamethasone 12 mg|DRUG: Dexamethasone 12 mg + dexmedetomidine 1 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Extension Study to Assess Adverse Events of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Age) With Migraine
Status: ENROLLING_BY_INVITATION
Conditions: Migraine Prophylaxis
Interventions: DRUG: Atogepant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reading Analysis in Ophthalmologic Patients
Status: UNKNOWN
Conditions: Diabetic Maculopathy|Age Related Macular Degeneration|Glaucoma|Epiretinal Membrane
Interventions: DEVICE: EyeTracker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cervical Erector Spinae Block for Shoulder Surgery
Status: UNKNOWN
Conditions: Postoperative Pain|Shoulder Surgery
Interventions: OTHER: Cervical erector spinae plane block|DEVICE: Intravenous morphine patient controlled analgesia device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single-arm Study to Evaluate the Safety and Efficacy of Sorafenib, in Subjects With BRAF Mutation Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Keratinocyte Suspension Versus Adipose-Derived Stem Cell-Keratinocyte Suspension for Post-Burn Raw Area
Status: UNKNOWN
Conditions: Burn With Full-Thickness Skin Loss
Interventions: PROCEDURE: Non-cultured Autologous Keratinocyte Suspension|PROCEDURE: Adipose-Derived Stem cell-Keratinocyte Suspension|PROCEDURE: Split skin graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT