pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of TroVax Vaccine Given in Conjunction With IL-2 for Treatment of Stage IV Renal Cell Cancer
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: BIOLOGICAL: TroVax|BIOLOGICAL: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Systane Versus Saline in Maintaining Tear Film Stability at Determined Time Points
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca
Interventions: DRUG: Systane Ocular Drops (OTC)|DRUG: Placebo - Saline Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old
Status: COMPLETED
Conditions: Nasolacrimal Duct Obstruction
Interventions: PROCEDURE: Immediate Office Probing|PROCEDURE: Deferred Facility Probing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Zilovertamab Vedotin (MK-2140) for Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) (MK-2140-004)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: MK-2140 (zilovertamab vedotin)|BIOLOGICAL: MK-2140 (zilovertamab vedotin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Biological Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: DRUG: Cisplatin|DRUG: dacarbazine|DRUG: Granulocyte-macrophage colony-stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphological Analysis of Meibomian Glands
Status: RECRUITING
Conditions: Meibomian Gland Dysfunction
Interventions: PROCEDURE: Thermal pulsation|PROCEDURE: Intense pulsed light therapy|PROCEDURE: Manual warm compresses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Moderate Hypothermia in Neonatal Hypoxic Ischemic Encephalopathy
Status: COMPLETED
Conditions: Neonatal Asphyxial Encephalopathy|Hypoxic Ischemic Encephalopathy
Interventions: OTHER: hypothermia|OTHER: normothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy of QYHJ and Standard Chemotherapy in the Treatment of Advanced Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Neoplasms
Interventions: DRUG: QingyiHuaji optimized formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transnasal Versus Suprazygomatic SPG Block in Persistant Idiopathic Facial Pain
Status: COMPLETED
Conditions: Headache|Persistent Idiopathic Facial Pain
Interventions: DRUG: Transnasal Sphenopalatine ganglion block|DRUG: Ultrasound-guided suprazygomatic sphenopalatine ganglion block
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: PCOS
Interventions: DRUG: Sitagliptin|BEHAVIORAL: Lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuropsychological Development and Functional Outcome Sin Children With Hirschsprung Disease at School Age
Status: COMPLETED
Conditions: Hirschsprung's Disease (HD)
Interventions: BEHAVIORAL: psychometric evaluation|BEHAVIORAL: neuropsychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of Variably Aged MK-0974 Tablets (MK-0974-038)(COMPLETED)
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: telcagepant potassium|DRUG: MK-0974 5Mo5C|DRUG: MK-0974 12Mo5C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: milrinone|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC
Status: ACTIVE_NOT_RECRUITING
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study of Flurpiridaz (18F) Injection for PET Imaging for Assessment of MPI Quality Using HPLC and SPE Manufacturing Processes
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)|Ischemic Heart Disease
Interventions: DRUG: Flurpiridaz (18F) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study
Status: TERMINATED
Conditions: Cleft Lip and Palate
Interventions: BEHAVIORAL: Interactive story teller LUNII
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Whole Body Vibration in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spastic
Interventions: OTHER: conventional physiotherapy program|OTHER: whole body vibration training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Sodium Thiosulfate Eardrops on Hearing Loss in Patients Who Receive Cisplatin Therapy
Status: TERMINATED
Conditions: Cancer
Interventions: PROCEDURE: Insertion of Pressure Equalization (PE) Tubes|DRUG: Sodium Thiosulfate (STS)|OTHER: Saline (Placebo)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Low- or Intermediate-Grade Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: chemotherapy|PROCEDURE: in vitro-treated peripheral blood stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Optimized Remote Ischemic Conditioning (RIC) Treatment for Patients With Chronic Cerebral Ischemia
Status: UNKNOWN
Conditions: Chronic Cerebral Ischemia|Intracranial Atherosclerosis
Interventions: DEVICE: Remote ischemic conditioning|DEVICE: Remote ischemic conditioning|DEVICE: Remote ischemic conditioning|DEVICE: Remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia
Interventions: DIETARY_SUPPLEMENT: Heavy Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study Evaluating PRO-232 an Ophthalmic Solution Compared to Placebo.
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: PRO-232|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Innovative Game-Aided Rehabilitation Platform for Rehabilitation of Balance in Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Computer Games-Aided Balance Training Protocol|OTHER: Conventional Balance Training Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: X-ray Dose Reduction Study for Endovascular Interventional Radiology
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: RADIATION: Low-dose DSA (83% reduction compared to normal dose) with novel X-ray imaging technology.|RADIATION: Normal dose DSA with conventional X-ray imaging technology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies
Status: RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: OTHER: Acquisition of blood samples and tumour tissue samples (biopsies)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care
Status: COMPLETED
Conditions: Lip and Oral Cavity Squamous Cell Carcinoma|Oral Cavity Verrucous Carcinoma|Stage 0 Lip and Oral Cavity Cancer|Tongue Cancer
Interventions: PROCEDURE: fluorescence imaging|PROCEDURE: biopsy|PROCEDURE: examination|PROCEDURE: Comparison of surgical margins by COE vs. DVFE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Status: UNKNOWN
Conditions: Orbital Fractures
Interventions: PROCEDURE: operative fracture size vs CT fracture size|PROCEDURE: orbital fracture intraoperative measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Evaluation of Positioning Protocols on a Wheelchair in Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegia and/or Hemiparesis Following Stroke
Interventions: OTHER: Arm 1|OTHER: Arm 2|OTHER: Arm 3|OTHER: Arm 4|OTHER: Arm 5|OTHER: Arm 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RALOX or CAPOX + Bevacizumab in the First-line Treatment of Advanced CRC(ROCB Study)
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Raltitrexed|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head COOLing in iscHemic Stroke Patients Undergoing EndovAscular Thrombectomy: a Feasibility and Safety stuDy
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute
Interventions: DEVICE: External active conductive head cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of a Vaccine for Prostate Cancer That Uses Each Patients' Own Immune Cells.
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: vaccine vehicle only|BIOLOGICAL: DC/LNCaP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Clinical Study of JMKX003142 Tablets
Status: RECRUITING
Conditions: Safety and Tolerability
Interventions: DRUG: JMKX003142 will be administered orally|DRUG: JMKX003142 will be administered orally|DRUG: JMKX003142 will be administered orally|DRUG: Placebo in Cohorts 1 to 7|DRUG: Placebo in 3 Cohorts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort Study
Status: COMPLETED
Conditions: Off-spring Cancer Risk
Interventions: BEHAVIORAL: nutrition counseling|DIETARY_SUPPLEMENT: multivitamin supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Risk Evaluation and Stratification of Low Risk for Cardiovascular Disease in Women
Status: UNKNOWN
Conditions: Chest Pain
Interventions: DIAGNOSTIC_TEST: Coronary Computed Tomography Angiography (CCTA)|OTHER: Cardiac Link
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Effect of Testosterone and Estradiol on NP Responses to Acute and Chronic Salt Loading
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: leuprolide acetate|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Consumption of Resistant Starch Type-4 (RS4)
Status: WITHDRAWN
Conditions: Cholesterol, Elevated|Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: RS4 bar|DIETARY_SUPPLEMENT: Control bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pudendal Nerve Fluoroscopic Guided Pulsed Radiofrequency for Treatment of Superficial Dyspareunia
Status: COMPLETED
Conditions: Superficial Dyspareunia
Interventions: PROCEDURE: pudendal nerve pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Phyto Aromatherapy Treatment in the Management of Recurrent Cystitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cystitis Recurrent
Interventions: COMBINATION_PRODUCT: CYSCONTROL/PHYTOCYST Herbal tea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Gather Information How Often Venous Thromboembolism Occurs in Prostate Cancer Patients in Sweden and How This Condition is Treated With Blood Thinners
Status: COMPLETED
Conditions: Venous Thromboembolism (VTE)
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Apixaban(Eliquis)|DRUG: Pradaxa (Dabigatran etexilate)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Higher Dose Preoperative taMOxifen in Premenopausal bREast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Premenopausal Breast Cancer|Hormone Receptor-positive Breast Cancer
Interventions: DRUG: Tamoxifen Oral Product|DIAGNOSTIC_TEST: Assessment of Ki-67|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL
Status: RECRUITING
Conditions: Partial Lipodystrophy
Interventions: DRUG: metreleptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xenografts With Platelet-rich Fibrin Versus Autogenous Bone in Alveolar Cleft Grafting
Status: UNKNOWN
Conditions: Alveolar Cleft
Interventions: PROCEDURE: secondary alveolar bone graft|PROCEDURE: Harvesting of the autogenous bone graft|PROCEDURE: Preparation of PRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Wisconsin Ginseng for Decreasing Cancer Related Fatigue
Status: RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm
Interventions: DIETARY_SUPPLEMENT: American Ginseng|DRUG: Placebo Administration|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sexual Health and Rehabilitation After Ovarian Suppression Treatment
Status: COMPLETED
Conditions: Breast Cancer Survivors|Sexual Function Disturbances|Ovarian Suppression Treatment
Interventions: BEHAVIORAL: Group Session|BEHAVIORAL: Telephone Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Dental Waterjet on Oral Hygiene for Patients With Braces
Status: UNKNOWN
Conditions: Oral Hygiene
Interventions: DEVICE: Dental Water Jet|DEVICE: Dental Floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Lung Diseases, Obstructive
Interventions: PROCEDURE: Nasal lavage|PROCEDURE: Nasal filter paper|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cafedrin/Theodrenalin (Akrinor®) Versus Ephedrine for Treatment of Hypotension in the Peri-operative Phase in Inpatient Setting
Status: COMPLETED
Conditions: Hypotension
Interventions: DRUG: Cafedrine/theodrenaline|DRUG: Ephedrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy, Safety, Tolerability and Pharmacokinetics of KAE609 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infection
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: KAE609
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Single Dose Pain Therapy in Patients With Painful Diabetic Neuropathy (0000-115)
Status: WITHDRAWN
Conditions: Painful Diabetic Neuropathy
Interventions: DRUG: Comparator: A: Pregabalin|DRUG: Comparator: B: Duloxetine|DRUG: Comparator: C: Diphenhydramine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Is There an Interest in Repeating the Vaginal Administration of Dinoprostone (Propess®), to Promote Induction of Labor of Pregnant Women at Term?
Status: TERMINATED
Conditions: Cervical Ripening|Pregnancy
Interventions: DRUG: Dinoprostone|DRUG: Oxytocine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control
Status: COMPLETED
Conditions: Cesarean Section Complications|Pain|Opioid Use
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine Hydrochloride|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL
Status: NOT_YET_RECRUITING
Conditions: Philadelphia Chromosome Negative ALL|Acute Lymphoblastic Leukemia, Adult
Interventions: COMBINATION_PRODUCT: CAR-T cells|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of Iloprost Inhaled in Pulmonary Hypertension After Repair of Congenital Heart Diseases (CHD)
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: iloprost nebuliser solution|DRUG: distilled water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin
Status: COMPLETED
Conditions: Low Back Pain|Neuropathic Pain
Interventions: DRUG: Tapentadol Prolonged Release|DRUG: Tapentadol Prolonged Release with Pregabalin|DRUG: Tapentadol Prolonged Release open label maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Finasteride for Chronic Central Serous Chorioretinopathy
Status: TERMINATED
Conditions: Retinal Disease
Interventions: DRUG: Finasteride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Diagnostic Efficacy of Different Suction Techniques for EUS-FNB of Pancreatic Solid Lesions
Status: UNKNOWN
Conditions: Pancreatic Mass
Interventions: DIAGNOSTIC_TEST: standard suction|DIAGNOSTIC_TEST: slow pull|DIAGNOSTIC_TEST: wet suction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Retrospective Analysis to Describe Patient Profiles, Current Treatment Patterns and Economic Burden for Asthma Patients in UAE. A Descriptive Analysis of the Asthma Patient Population in the Emirate of Dubai With Respect to Healthcare Resource Utilization, Costs, and Asthma-related Treatment Pattern
Status: COMPLETED
Conditions: Asthma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients
Status: RECRUITING
Conditions: The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Sorafenib as a Salvage Treatment for Relapsed or Refractory Acute Myeloid Leukemia Carrying FLT3-ITD
Status: COMPLETED
Conditions: FLT3-ITD Mutation|AML
Interventions: DRUG: Sorafenib 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Integrative Medicine for Hypermobility Spectrum Disorder and Ehlers-Danlos Syndromes (IMforHSDandEDS)
Status: COMPLETED
Conditions: Ehlers-Danlos Syndrome|Hypermobile EDS (hEDS)|Hypermobility Syndrome|EDS
Interventions: BEHAVIORAL: Anti-inflammatory (Mediterranean-style) diet|BEHAVIORAL: Behavioral and psychosocial support
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Community-based Intergenerational Oral Health Study
Status: UNKNOWN
Conditions: Preventive Health Services
Interventions: BEHAVIORAL: motivational interviewing counseling|BEHAVIORAL: motivational interviewing counseling|BEHAVIORAL: motivational interviewing counseling|BEHAVIORAL: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Association Between Serum Periostin Levels and Cortical Porosity in Patients With Secondary Hyperparathyroidism
Status: COMPLETED
Conditions: Hyperparathyroidism
Interventions: DEVICE: HR-pQCT|OTHER: blood specimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory B-cell Malignancies
Status: UNKNOWN
Conditions: Acute Lymphocytic Leukemia|Chronic Lymphocytic Leukemia|Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: CAR-NK-CD19 Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Avascular Necrosis
Interventions: DRUG: Atorvastatin|PROCEDURE: MRI, Venipuncture|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Drug-eluting Balloon vs. Conventional Balloon in the Treatment of (re)Stenosis (Dialysis Fistulae)
Status: COMPLETED
Conditions: Vascular Access Complication|Restenosis, Vascular Graft|Dialysis Related Complications
Interventions: DEVICE: Conventional angioplasty|DEVICE: Angioplasty with drug-eluting balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safeguarding the Brain of Our Smallest Infants Phase III
Status: COMPLETED
Conditions: Infant, Extremely Premature|Brain Injuries|Death, Brain|Death; Neonatal
Interventions: OTHER: Modify cardio-respiratory support to avoid cerebral hypoxia|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Trastuzumab Emtansine in Patients With HER2-Equivocal Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulsing Electrical Fields on Lower Extremity Diabetic Neuropathy: A Pilot, Open-Label Study
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DEVICE: MedRelief SE 55
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)
Status: ACTIVE_NOT_RECRUITING
Conditions: Secondary Progressive Multiple Sclerosis
Interventions: DRUG: Tolebrutinib|DRUG: Placebo to match Tolebrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Inhaled TD-8236 on Allergen-induced Asthmatic Response
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: TD-8236|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Efficacy Study of Benzydamine Oral Rinse for the Treatment of Oral Mucositis (Mouth Sores) Resulting From Radiation Therapy for Cancer of the Oral Cavity, Oropharynx, or Nasopharynx
Status: COMPLETED
Conditions: Stomatitis|Radiation Effects
Interventions: DRUG: Benzydamine Hydrochloride 0.15% Oral Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of 7 Days of Dosing With a 10 mg Rectal Suppository of NRL001in Patients With Faecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DRUG: NRL001|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ibuprofen 200 mg Gel Capsules of Dr. Reddy's Laboratories Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: U-CHAMP: Urban Cardiovascular Health Assessment and Management Program
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Hypertension|Hyperlipidemia|Hyperglycemia
Interventions: OTHER: participant referral to primary care network physician
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Immediate Effects of Thoracic Transverse Mobilization in Patients With Primary Complaint of Mechanical Neck Pain: A Pilot Study
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: OTHER: Transverse vertebral pressures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Infusion Rates of Tocilizumab in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: tocilizumab [RoActemra/Actemra]|DRUG: tocilizumab [RoActemra/Actemra]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products
Status: NOT_YET_RECRUITING
Conditions: Oral Mucositis
Interventions: OTHER: Honey product|OTHER: propolis|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety/Tolerability of Grass MATA MPL
Status: COMPLETED
Conditions: Type I Hypersensitivity
Interventions: BIOLOGICAL: Grass MATA MPL|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Hepatocellular Carcinoma (Liver Cancer)
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: bortezomib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Decitabine and Cedazuridine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety, Tolerability, and Pharmacokinetics of DF-003 in Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy|Safety and Tolerability
Interventions: DRUG: DF-003|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
Status: RECRUITING
Conditions: Hyperlipoproteinemia (a)
Interventions: DRUG: Pelacarsen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-operative Versus Operative Treatment of Acute Acromioclavicular Joint Dislocation
Status: COMPLETED
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: Open Reduction Internal Fixation of AC joint dislocation|OTHER: Non operative treatment of AC joint dislocation (sling)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Safety, Tolerability and Pharmacokinetics of Oral Dabrafenib In Children and Adolescent Subjects
Status: COMPLETED
Conditions: Neoplasms, Brain
Interventions: DRUG: Dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel
Status: TERMINATED
Conditions: Chemotherapeutic Agent Toxicity|Pain|Peripheral Neuropathy|Recurrent Breast Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Therapy-related Toxicity
Interventions: PROCEDURE: cryotherapy|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment|PROCEDURE: management of therapy complications|PROCEDURE: assessment of therapy complications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Astra Tech Fixture ST
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Anesthesia and Simple Maneuver on Shoulder Pain After Gynecologic Laparoscopy
Status: COMPLETED
Conditions: Gynecologic Laparoscopic Surgery for Benign Adnexa Disease
Interventions: PROCEDURE: Intraperitoneal instillation of bupivacaine|PROCEDURE: CO2 removal by means of a pulmonary recruitment maneuver|PROCEDURE: Intraperitoneal instillation of bupivacaine +CO2 removal by means of a pulmonary recruitment maneuver|OTHER: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: RFC and MTHFR SNPs & hENT1- dCK Expression as Prognostic Factors in ALL & hENT1- dCK Expression as Prognostic Factors in AML
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia.|Acute Myeloblastic Leukemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biochemical Effects of Remote Ischemic Pre-Conditioning on Contrast-induced Acute Kidney Injury
Status: ACTIVE_NOT_RECRUITING
Conditions: Contrast-induced Acute Kidney Injury
Interventions: DEVICE: RIPC|DEVICE: Sham-RIPC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)
Status: TERMINATED
Conditions: Progressive Multifocal Leukoencephalopathy
Interventions: DRUG: mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation
Status: COMPLETED
Conditions: Anxiety|Preoperative Care|Pharmacokinetics|Emergence Delirium
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Nicotinamide Riboside Supplementation in Allogeneic Hematopoietic Cell Transplantation
Status: RECRUITING
Conditions: Allogeneic Hematopoietic Cell Transplantation
Interventions: DRUG: Nicotinamide riboside (NR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosis: Early Detection, Intervention and Prevention
Status: COMPLETED
Conditions: Prodromal Schizophrenia|Psychotic Disorders|Severe Bipolar Disorder With Psychotic Features|Severe Major Depression With Psychotic Features
Interventions: BEHAVIORAL: Family-aided Assertive Community Treatment|BEHAVIORAL: Enhanced standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Inhaled FF 200mcg/GW642444M 25mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase II Trial of Perioperative Chemotherapy With Oxaliplatin, 5-Fluorouracil, Leucovorin(MODIFIED FOLFOX6) in Patients With Locally Advanced Operable Gastric Cancer
Status: COMPLETED
Conditions: Advanced Gastric Cancer
Interventions: DRUG: mFOLFOX6 (folinic acid, 5-fluorouracil, and oxaliplatin )
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ovarian Stimulation Using Recombinant Follicle-stimulating Hormone (FSH) and Gonadotrophin Releasing Hormone (GnRH) Agonist in Alternate Days
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Triptorelin|DRUG: Cetrorelix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: S9031-9333-0106-0112-A Study of Biomarkers in Samples From Patients With Acute Myeloid Leukemia Treated With Standard Chemotherapy With or Without Gemtuzumab Ozogamicin
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: DNA analysis|GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Everolimus-eluting Stents and Paclitaxel-eluting Stents for Coronary Revascularization in Daily Practice: The COMPARE Trial
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Acute Coronary Syndrome
Interventions: DEVICE: everolimus stent|DEVICE: paclitaxel stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mitigating PTSD-CUD After Sexual Assault
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Cannabis Use Disorder
Interventions: BEHAVIORAL: RISE Guide|BEHAVIORAL: Relaxation Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Social Norms, Messengers, and Processing Fluency to Increase Hypertension Medication Adherence
Status: COMPLETED
Conditions: Medication Adherence|Hypertension
Interventions: BEHAVIORAL: Scorecard|BEHAVIORAL: Social norms|BEHAVIORAL: Messenger effects|BEHAVIORAL: Processing fluency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Myopia Control Using Bright Light Therapy, Myopic Defocus and Atropine
Status: RECRUITING
Conditions: Myopia
Interventions: OTHER: High intensity light box for bright light therapy and single vision spectacle lenses|OTHER: High intensity light box for bright light therapy and Defocus Incorporated Multiple Segments (DIMS) spectacle lenses|OTHER: High intensity light box for bright light therapy and atropine 0.01% eye drop and and single vision spectacle lenses|OTHER: Atropine 0.01% eye drop and and single vision spectacle lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Demonstrate the Relative Bioavailability of Alprazolam Tablets, 1 mg
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: Alprazolam Tablets, 1 mg (Geneva Pharmaceuticals)|DRUG: Alprazolam Tablets, 1 mg (The Upjohn Company)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Afatinib In Combination With Cisplatin Or Carboplatin + Pemetrexed In Patients With EGFR-Mutant Lung Cancers Undergoing Definitive Chemoradiation
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Afatinib|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed|RADIATION: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DB289 Versus TMP-SMX for the Treatment of Acute Pneumocystis Jiroveci Pneumonia (PCP)
Status: TERMINATED
Conditions: Pneumonia, Interstitial Plasma Cell|Pneumocystis Carinii Pneumonia|Pneumonia, Pneumocystis Carinii|HIV Infections
Interventions: DRUG: Pafuramidine maleate (DB289)|DRUG: Trimethoprim-Sulfamethoxazole (TMP-SMX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Ropinirole Extended Release (XR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies
Status: RECRUITING
Conditions: Refractory Focal Epilepsy|Focal Cortical Dysplasia|Hemimegalencephaly|Tuberous Sclerosis|Mild Malformation of Cortical Development With Oligodendroglial Hyperplasia in Epilepsy (MOGHE)
Interventions: GENETIC: Sampling of blood, frozen resected tissues, and cerebrospinal fluid (CSF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Developmental Framework For Linking Phonological And Morpho-syntactic Sequential Pattern Rules In DLD: Production
Status: RECRUITING
Conditions: Developmental Language Disorder|Speech Sound Disorder|Specific Language Impairment
Interventions: OTHER: Sensitivity to phonological rules|OTHER: Sensitivity to semantic category cues.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase II Study of Sunitinib Rechallenge in Patients With Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pazopanib Versus Sunitinib in the Treatment of Locally Advanced and/or Metastatic Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study Randomized Evaluating the Efficacy of Auriculotherapy in Patients With Musculoskeletal Pain by Aromatase Inhibitors
Status: RECRUITING
Conditions: Musculoskeletal Pain|Breast Cancer
Interventions: DEVICE: Auriculotherapy for analgesic use|DEVICE: Placebo auriculotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: QVA149|DRUG: QAB149|DRUG: NVA237|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Recurrent Melanoma|Refractory Malignant Solid Neoplasm|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Riluzole|DRUG: Sorafenib Tosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin (Diferuloylmethane Derivative) With or Without Bioperine in Patients With Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Curcumin|DRUG: Bioperine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Paediatric Asthma Management
Status: COMPLETED
Conditions: Asthma in Children
Interventions: DIETARY_SUPPLEMENT: Bifiasthm|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Effects of a New Interface on Lung Ventilation and Gas Distribution
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: High Flow Nasal Cannula (HFNC)|DEVICE: Continuous Positive Airway Pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT