pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Open-Label Extension Study of BPN14770 in Subjects With Fragile X Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Fragile X Syndrome
Interventions: DRUG: Zatolmilast/ BPN14770
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Valsartan and Amlodipine Combined and Alone in Patients With Hypertension.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan+amlodipine combination, valsartan, amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Ibuprofen Enantiomers Compared With Standard Brufen Sirup in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen syrup|DRUG: Brufen syrup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Auricular Acupressure on Improving Constipation Among Residents in Community Rehabilitation Center
Status: COMPLETED
Conditions: Schizophrenia|Constipation
Interventions: OTHER: Auricular acupressure|OTHER: health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Economic and Cognitive Effects of Pain Reduction
Status: TERMINATED
Conditions: Pain, Chronic
Interventions: DRUG: Ibuprofen 600 mg|DIETARY_SUPPLEMENT: Prenatal vitamins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vibrotactile Coordinated Reset: A Non-invasive Treatment for Parkinson's Disease 2
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Active vibrotactile coordinated reset|DEVICE: Sham vibrotactile coordinated reset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
Status: RECRUITING
Conditions: Dementia|Chronic Disease|Neoplasm Metastasis|Lung Neoplasm|Pulmonary Disease, Chronic Obstructive|Heart Failure，Congestive|Liver Cirrhosis|Kidney Failure, Chronic|Lung Diseases, Interstitial|Peripheral Vascular Diseases|Diabetes With End Organ Damage|Palliative Care, Patient Care|Health Care Quality, Access, and Evaluation|Patient Care|Health Communication|Patient Care Planning|Quality of Life
Interventions: BEHAVIORAL: Jumpstart Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Bioavailability Study of Clarithromycin 500 mg Tablets in Fasting State
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clarithromycin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Effect of Herbal Infusion on Menometrorrhagia
Status: COMPLETED
Conditions: Abnormal Uterine Bleeding|Menorrhagia; Postmenopausal|Metrorrhagia|Hysterectomy|Heavy Menstrual Bleeding
Interventions: DIETARY_SUPPLEMENT: Tea infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combined Iron Protocols on Perioperative Allogeneic Transfusion
Status: RECRUITING
Conditions: Anemia|Iron Deficiency Anemia|Perioperative|Transfusion|Cardiac Surgery
Interventions: DRUG: Iron sucrose, Human Erythropoietin Injection, Vitamin C|DRUG: Standard Medical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of Anacetrapib (MK-0859) When Added to Ongoing Statin Therapy in Japanese Participants With Dyslipidemia (MK-0859-051 AM1)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: Anacetrapib|DRUG: Placebo for anacetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: What's Happen Under the Calcification Process in Pseudoxanthoma Elasticum
Status: COMPLETED
Conditions: Pseudoxanthoma Elasticum
Interventions: RADIATION: PET scan 18-FDG and 18-NAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Etripamil Nasal Spray Self-Administration for the Termination of Spontaneous Episodes of Paroxysmal Supraventricular Tachycardia
Status: ACTIVE_NOT_RECRUITING
Conditions: Tachycardia, Supraventricular|Paroxysmal Supraventricular Tachycardia
Interventions: DRUG: Etripamil NS 70 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Speed of Processing Training to Improve Cognition in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Speed of Processing Training (SPT)|BEHAVIORAL: Placebo Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GS-5885 Alone or in Combination With GS-9451 With Peginterferon Alfa 2a and Ribavirin in Treatment Chronic Genotype 1 Hepatitis C Virus
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: GS-5885|DRUG: GS-9451|BIOLOGICAL: peginterferon alfa-2a|DRUG: ribavirin tablet|DRUG: GS-9451 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tucidinostat, Azacitidine Combined With CHOP Versus CHOP in Patients With Untreated Peripheral T-cell Lymphoma
Status: RECRUITING
Conditions: T-cell Lymphoma
Interventions: DRUG: Tucidinostat, Azacitidine combined with CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Partial Sleep Deprivation on Cognitive Function of Anesthesiologists
Status: COMPLETED
Conditions: Cognitive Dysfunction|Sleep Deprivation
Interventions: OTHER: The Psychomotor Vigilance Task (PVT)|OTHER: Epworth Sleepiness Scale|OTHER: Karolinska sleeping scale|OTHER: Trail making test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache
Status: COMPLETED
Conditions: Post-Traumatic Headache|Mild Traumatic Brain Injury|Post-Concussion Syndrome
Interventions: DRUG: AMG 334
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Abametapir Lotion Administered for the Treatment of Head Lice Infestation
Status: COMPLETED
Conditions: Head Lice Infestation
Interventions: DRUG: Abametapir Lotion 0.74% w/w|DRUG: Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omnaris Versus Levocetirizine Phase 4 Study
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Ciclesonide|DRUG: Levocetirizine|DRUG: Ciclesonide & Levocetirizine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cuddle and Calm Booklets on Parent-Child Emotional Connection a Nurture-based Children's Book
Status: WITHDRAWN
Conditions: Emotional Problem
Interventions: BEHAVIORAL: Poem book about relational health|BEHAVIORAL: Poem book about physical health and safety
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Three Noninvasive Ventilation Modes: a Physiological Study in Healthy Volunteers
Status: COMPLETED
Conditions: Respiratory Failure|Non Invasive Ventilation on Healthy Volunteer
Interventions: DEVICE: Non invasive ventilation HELMET|DEVICE: Non invasive ventilation facemask (Respironics)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Experimental Changes in Children's Sleep Duration and Timing: Effect on Obesity and Type 2 Diabetes Risk
Status: COMPLETED
Conditions: Type2 Diabetes|Sleep
Interventions: BEHAVIORAL: Sleep duration 90 min|BEHAVIORAL: Sleep duration 45 min|BEHAVIORAL: Sleep timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma|Immunotherapy|Biomarkers
Interventions: DRUG: adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Multiple Dose Study to Compare the Effects of AMG 223 and Sevelamer HCL (Renagel®)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AMG 223|DRUG: Renagel® (sevelamer hydrochloride)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Fedovapagon for Nocturia in Men With Benign Prostatic Hyperplasia (BPH)
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: Fedovapagon 2 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve
Status: RECRUITING
Conditions: Aortic Stenosis, Severe
Interventions: DEVICE: SAPIEN X4 THV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgical Interventions for the Treatment of Humeral Shaft Fractures
Status: UNKNOWN
Conditions: Fracture of Shaft of Humerus|Humerus Fracture
Interventions: PROCEDURE: Bridge Plate osteosynthesis|PROCEDURE: Locked intramedullary nail osteosynthesis|PROCEDURE: Open reduction and plate osteosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors
Status: RECRUITING
Conditions: Oesophageal Cancer|Quality of Life|Bacterial Overgrowth
Interventions: DIAGNOSTIC_TEST: Breath test|DIAGNOSTIC_TEST: Saliva sample|DIAGNOSTIC_TEST: Blood sample|DIAGNOSTIC_TEST: Urine sample|DIAGNOSTIC_TEST: Stool sample|DIAGNOSTIC_TEST: Health-related Quality of life questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Dose BAYA1040_Nifedipine: a Dose-comparative Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nifedipine (Adalat, BAYA1040)|DRUG: Nifedipine (Adalat, BAYA1040)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Hepatitis C, Chronic|Cardiovascular Diseases
Interventions: DRUG: Epclusa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose-Guided Eating Pilot
Status: NOT_YET_RECRUITING
Conditions: Postmenopausal|Prediabetes|Adolescent and Young Adult (AYA) Cancer Survivors
Interventions: BEHAVIORAL: Glucose-Guided Eating with CGM|OTHER: CGM only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality on Pain, Stress, and Affect in the Infusion Clinic
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Chemotherapy
Interventions: BEHAVIORAL: Virtual reality therapy|BEHAVIORAL: Questionnaires|PROCEDURE: Measure heart rate|BEHAVIORAL: Cyber sickness measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Establishing of Neuronal-like Cells From Patients With Cisplatin-Induced Peripheral Neuropathy
Status: WITHDRAWN
Conditions: Peripheral Nervous System Diseases|Testicular Neoplasms
Interventions: PROCEDURE: Blood sample collection|BEHAVIORAL: Report of peripheral neuropathy after cisplatin therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Pharmacokinetics Study of CARD-024 in Healthy Subjects
Status: COMPLETED
Conditions: Drug Safety|Heart; Disease, Activity
Interventions: DRUG: CARD-024|OTHER: Drug Carrier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents
Status: COMPLETED
Conditions: Risk Reduction Behavior|Health Behavior|Sexual Behavior|Adolescent Behavior|Cannabis
Interventions: BEHAVIORAL: INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY)|BEHAVIORAL: SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH)|BEHAVIORAL: SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Trial of Rebamipide Liquid to Determine the Effective Dose for Prevention of Chemoradiotherapy-induced Oral Mucositis in Patients With Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Placebo|DRUG: 2% Rebamipide liquid|DRUG: 4% Rebamipide liquid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Non-Weightbearing Stationary Elliptical Machines for Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain|Low Back Pain
Interventions: OTHER: Using sitting ellipticals|OTHER: Physiotherapy Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy of a Homeopathic Protocol in Patients With Non-metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer Female|Joint Pain
Interventions: DRUG: Rhus toxicodendron 9 CH + Ruta graveolens 5 CH (Homeopathic Granules)|OTHER: paracetamol (drug analgesic class1)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fosaprepitant in Patients Receiving Ifosfamide-based Regimen
Status: COMPLETED
Conditions: Sarcoma|Chemotherapy-induced Nausea and Vomiting|Effects of Chemotherapy|Adverse Effects of Medical Drugs
Interventions: DRUG: Fosaprepitant|DRUG: Dexamethasone|DRUG: 5HT3 receptor antagonist|DRUG: Ifosfamide-based chemotherapy (AI)|DRUG: Doxorubicin|DRUG: Mesna|DRUG: Ifosfamide|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Provocative Testing Using LHRH and hCG of the Pituitary-Gonadal Axis in Persons With Spinal Cord Injury.
Status: COMPLETED
Conditions: Hypogonadism|Spinal Cord Injury
Interventions: DRUG: Human chorionic gonadotropin (hCG)|DRUG: Luteinizing hormone releasing hormone (LHRH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long Term Effects of Lutein/Zeaxanthin and Omega-3- Supplementation for Two More Years (LUTEGA 2)
Status: COMPLETED
Conditions: Age Related Maculopathy
Interventions: DIETARY_SUPPLEMENT: Lutein/ Zeaxanthin + Omega- 3- Fatty Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH
Status: TERMINATED
Conditions: Hypercholesterolemia
Interventions: DRUG: SPC5001|DRUG: Saline 0.9%|DRUG: SPC5001|DRUG: SPC5001|DRUG: SPC5001|DRUG: SPC5001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydrogen-Oxygen Generator With Nebulizer for Rehabilitation Treatment of COVID-19
Status: RECRUITING
Conditions: COVID-19|AMS-H-03|Hydrogen-oxygen Gas
Interventions: DEVICE: Hydrogen-Oxygen Generator with Nebulizer, AMS-H-03|OTHER: basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prenatal Treatment of Congenital Cytomegalovirus Infection With Letermovir Randomized Against Valaciclovir - STEP 1 (CYMEVAL3-STEP1)
Status: COMPLETED
Conditions: Pregnant Women Undergoing TOP|TOP - Failed Attempted Termination of Pregnancy
Interventions: DRUG: Letermovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effectiveness of CFT for Reducing Self-criticism in Patients With Complex PTSD: a Single-case Experimental Study
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Compassion-focused therapy (CFT) for complex PTSD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAT7104 Injection in Patients With Advanced Malignant Tumors.
Status: RECRUITING
Conditions: Advanced Malignant Tumor
Interventions: DRUG: BAT7104 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quality of Life in Patients With Statin-Associated Myopathy
Status: TERMINATED
Conditions: Statin Adverse Reaction
Interventions: DRUG: Statins|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Pembrolizumab, Ibrutinib and Rituximab in PCNSL
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma|Recurrent Cancer|Refractory Cancer|Relapsed Cancer
Interventions: DRUG: Ibrutinib|DRUG: Pembrolizumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oncolytic MG1-MAGEA3 With Ad-MAGEA3 Vaccine in Combination With Pembrolizumab for Non-Small Cell Lung Cancer Patients
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: Ad-MAGEA3|BIOLOGICAL: MG1-MAGEA3|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Micro-Randomized Trial to Optimize Just-in-Time Adaptive Intervention for Binge Eating & Weight-related Behaviors
Status: RECRUITING
Conditions: Binge Eating|Obesity
Interventions: BEHAVIORAL: FoodSteps behavioral intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer Metastatic
Interventions: DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterise Immune Responses Following Immunisations With "Fendrix" or "Engerix B" Hepatitis B Vaccines
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix B IM injection - 20ug|BIOLOGICAL: Fendrix IM injection - 20ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome
Status: COMPLETED
Conditions: Burnout Syndrome|Neutrophil-Lymphocyte Ratio|Interleukin-6|Interleukin-10
Interventions: OTHER: music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Balloon Kyphoplasty, Vertebroplasty and Conservative Management in Acute Osteoporotic Vertebral Fractures
Status: COMPLETED
Conditions: Osteoporotic Vertebral Fracture|Between T5 and L5|of Less Than 6 Weeks Duration
Interventions: OTHER: conventional treatment|PROCEDURE: kyphoplasty with balloons|PROCEDURE: vertebroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Power Walking in Cardiac Patients Who Underwent Post-coronary Angioplasty
Status: COMPLETED
Conditions: Heart Diseases, Ischemic|Coronary Artery Disease|Coronary Arteriosclerosis|Coronary Syndrome|Coronary Disease
Interventions: BEHAVIORAL: Power walking|BEHAVIORAL: Standardised outpatient cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of MV130 in Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: MV130
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Research of Human Mesenchymal Stem Cells in the Treatment of COVID-19 Pneumonia
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: UC-MSCs|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Markers to Measure Clotting in Patients With the Obstructive Sleep Apnoea Hypopnoea Syndrome
Status: COMPLETED
Conditions: Obstructive Sleep Apnoea Hypopnoea Syndrome|Biomarkers of Fibrin Clot Structure|Biomarkers of Vascular Endothelial Injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CuMulativE Live bIrth Rate of Patients at High Risk of OHSS After Freeze-all Embryos at Cleavage or blAstocyst Stage
Status: UNKNOWN
Conditions: Infertility
Interventions: PROCEDURE: cryopreservation of embryos at cleavage stage|PROCEDURE: cryopreservation of embryos at blastocyst stage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing the Abuse of Opioids in Drug Users
Status: TERMINATED
Conditions: Opioid Abuse, Unspecified|Opioid Dependence
Interventions: DRUG: Oxycodone/Placebo|DRUG: Oxycodone/Risperidone|DRUG: Oxycodone/Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced/Metastatic Solid Tumors
Interventions: DRUG: ISM3412
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Water-contrast Transvaginal Ultrasonography Versus Sonovaginography for the Diagnosis of Posterior Deep Pelvic Endometriosis
Status: COMPLETED
Conditions: Endometriosis, Rectum|Endometriosis of Vagina|Endometriosis Rectovaginal Septum|Endometriosis Pelvic|Endometriosis of Colon|Endometriosis
Interventions: DIAGNOSTIC_TEST: Rectal water-contrast transvaginal ultrasonography|DIAGNOSTIC_TEST: Sonovaginography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Low Carbohydrate Versus Low Fat Diet in the Treatment of Dyslipidemia in Obese Children With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Dyslipidemias
Interventions: OTHER: Carbohydrate restricted group|OTHER: Standard low fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Analgesia by Infiltration of the Pudendal Nerve Prior to Sacrospinous Ligament Suspension
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Pudendal nerve block|PROCEDURE: Sham Pudendal nerve block|DRUG: Bupivacaine Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Parecoxib for Pain Management After Total Knee Arthroplasty and Total Hip Arthroplasty
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Parecoxib sodium|DRUG: Normal saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety of Dapivirine Gel and Film Formulations
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dapivirine Vaginal Film|DRUG: Dapivirine Vaginal Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum
Status: RECRUITING
Conditions: Erythema Nodosum Leprosum
Interventions: DRUG: Methotrexate|DRUG: Placebo|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing an Imaging-Based Tool to Identify Areas for Prostate Cancer Biopsy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Diagnostic MRI|PROCEDURE: Diagnostic Prostate Biopsy|DEVICE: Risk Map DSS tool
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: 68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma
Status: RECRUITING
Conditions: Carbonic Anhydrase IX|PET-CT|Clear Cell Renal Cell Carcinoma
Interventions: DRUG: 68Ga-C1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: encorafenib|DRUG: binimetinib|DRUG: pembrolizumab|DRUG: ipilimumab|DRUG: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Intravenous Denileukin Diftitox in Stage III or IV Ovarian Cancer
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer|Extraovarian Peritoneal Cancer|Fallopian Tube Carcinoma
Interventions: DRUG: Ontak
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Concomitant MTX on Efficacy, Safety and Adherence of Ustekinumab-treatment in Patients With Active PsA
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Methotrexate|DRUG: Ustekinumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Music Activity INTervention for Adherence Improvement Through Neurological Entrainment - II
Status: COMPLETED
Conditions: Physical Activity
Interventions: OTHER: Audiobooks|OTHER: Tempo-pace synchronized playlists|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.
Status: COMPLETED
Conditions: Pharmacological Action
Interventions: DRUG: Tranexamic Acid|DRUG: Sodium Chloride 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety Study of Valsartan and Chlorthalidone Conjugate Treatment Compared to Simple Treatment for Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: GROUP A: Valsartan plus Chlorthalidone|DRUG: GROUP B: Valsartan|DRUG: GROUP C: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dulce Digital 2.0 - Innovative Diabetes Self-Management in the Digital Age
Status: RECRUITING
Conditions: Diabetes Type 2
Interventions: BEHAVIORAL: Dulce Digital Text-Based Education|BEHAVIORAL: Project Dulce Telehealth|BEHAVIORAL: Project Dulce Live
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immersive Virtual Reality Treatment for Unilateral Spatial Neglect
Status: RECRUITING
Conditions: Stroke|Unilateral Spatial Neglect
Interventions: OTHER: Immersive Virtual Reality Intervention|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Thalidomide in Gastrointestinal Vascular Malformation Related Bleeding
Status: WITHDRAWN
Conditions: Gastrointestinal Hemorrhage|Vascular Malformation
Interventions: DRUG: Thalidomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Motor Skill Proficiency After Equine-assisted Activities and Brain-building Tasks
Status: COMPLETED
Conditions: Motor Delay|Motor Skills Disorders|Autism Spectrum Disorder|Attention Deficit Hyper Activity|Intellectual Disability|Sensory Disorders
Interventions: BEHAVIORAL: Equine-assisted activities|BEHAVIORAL: GaitWay program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Investigating LFP Correlates of TUS in Patients With Movement Disorders
Status: RECRUITING
Conditions: Parkinson Disease|Essential Tremor|Dystonia
Interventions: DEVICE: TUS Active|DEVICE: TUS Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis
Status: COMPLETED
Conditions: Primary Biliary Cirrhosis
Interventions: DIETARY_SUPPLEMENT: S-adenosyl-L-methionine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of New Tolvaptan Formulation in Subjects With ADPKD
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Tolvaptan MR|DRUG: Tolvaptan MR|DRUG: Tolvaptan MR|DRUG: Tolvaptan IR|DRUG: Tolvaptan MR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modafinil Versus Placebo for Hypoactive Delirium in the Critically Ill
Status: WITHDRAWN
Conditions: Delirium|Respiratory Failure
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Kinetics of Plasma and Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) in Patients With Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: BIOLOGICAL: Blood samples|OTHER: Cerebral MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) Trial
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: lisinopril|DRUG: carvedilol controlled release formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL)
Status: RECRUITING
Conditions: T-cell Lymphoblastic Lymphoma
Interventions: DRUG: Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin|DRUG: Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin|DRUG: Prednisone,Vincristine, Pegylated-asparaginase, Bortezomib,Cytarabine, Cyclophosphamide, Daunorubicin, 6-mercaptopurine, methotrexate, Dexamethasone, Doxorubicin, Vindesine, Etoposide, Ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion With Floxuridine and Systemic Irinotecan After Surgery in Treating Patients With Hepatic (Liver) Metastases From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: floxuridine|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cholinergic Health After Menopause (CHAMP)
Status: RECRUITING
Conditions: Postmenopausal Symptoms|Aging|Alzheimer Disease
Interventions: DRUG: Cholinergic antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Remodulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Tolerability of GDC-0068 in Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: GDC-0068
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomised Multi - Center Trial on the Repair of Large Hiatal Hernias: Absorbable Mesh vs. Pledgeted Sutures vs. Sutures Only
Status: NOT_YET_RECRUITING
Conditions: Hiatal Hernia
Interventions: DEVICE: Laparoscopic or robot-assisted hiatal closure (sutures only vs. absorbable mesh vs. pledgeted sutures) and fundoplication according to Toupet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bromfenac 0.09% vs Ketorolac 0.4% for Cyclosporine Induction Phase
Status: COMPLETED
Conditions: Dry Eye Disease|Ocular Comfort
Interventions: DRUG: bromfenac|DRUG: ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Doxycycline Outcomes in Lupus Erythematosus
Status: WITHDRAWN
Conditions: Cardiovascular Disease
Interventions: DRUG: Placebo|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study With Arctic Root Compared With the Extract When Combined With Schizandra and Russian Root (Adapt 232), Standardized Ginseng Extract and Placebo Regarding Impact on the Level of Energy, Ability to Work Under Stress, Quality of Life and Wellbeing, in Middleaged Women Who Are Still Employed
Status: COMPLETED
Conditions: Depression|Stress
Interventions: DRUG: Rhodiola rosea, L|DRUG: Rhodiola rosea, L., Eleutherococcus senticosus, Schisandra chinensis|DRUG: Panax ginseng|DRUG: Placebo - dark brown sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Add Glucokinase Activator to Target A1c
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TTP399 400 mg|DRUG: TTP399 800 mg|DRUG: Sitagliptin 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet
Status: COMPLETED
Conditions: Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose
Interventions: DRUG: 500 mg metformin hydrochloride extended release caplet (test drug)|DRUG: 500 mg metformin hydrochloride prolonged release tablet (reference drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation
Status: COMPLETED
Conditions: Leukaemia (Acute)|Leukaemia (Chronic)|Leukaemia (Acute Myeloid)|Leukaemia (Acute Lymphoblastic)|Leukaemia (Acute Promyelocytic)
Interventions: BIOLOGICAL: p.DOM-WT1-37 DNA Vaccine and p.DOM-WT1-126 DNA Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INcreasing Statin Prescribing in HIV Behavioral Economics REsearch
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV|Cardiovascular Diseases
Interventions: BEHAVIORAL: Knowledge assessment|BEHAVIORAL: Education Intervention|BEHAVIORAL: Provider Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sinus Floor Augmentation and Graft Compared Sinus Membrane Elevation With Blood Coagulum. A Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Implant Failed
Interventions: PROCEDURE: Maxillary sinus membrane elevation|PROCEDURE: Maxillary sinus floor augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Group Interventions for Suicidal African Americans
Status: WITHDRAWN
Conditions: Depression|Mental Illness|Suicide|Suicidal Ideation
Interventions: BEHAVIORAL: 10 weekly group meetings|BEHAVIORAL: Outpatient counseling and support groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sustained-release Oral Sodium Nitrite on Postoperative Pain and Recovery Following Total Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: DRUG: JAN101 SR|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab for HER2 Positive Relapsed/Refractory B-Acute Lymphoblastic Leukemia (B-ALL)
Status: TERMINATED
Conditions: Relapsed/Refractory Leukemia
Interventions: DRUG: Herceptin (trastuzumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilizing A Single Session Problem-Solving Intervention With Caregivers of Pediatric Patients Receiving Chronic Transfusion to Treat Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: Single Session Problem-Solving Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial to Evaluate OPC 67683 in Participants With Pulmonary Sputum Culture-positive, Multidrug-resistant Tuberculosis (TB)
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary|Tuberculosis, Multidrug Resistant|Extensively Drug-Resistant Tuberculosis
Interventions: DRUG: Delamanid|DRUG: Optimized Background Regimen (OBR)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Astaxanthin (2 mg) + Lycopene (1.8 mg) + D-Alpha-Tocopherol (10 IU) For The Treatment Of Skin Aging
Status: COMPLETED
Conditions: Skin Aging|Wrinkles
Interventions: DIETARY_SUPPLEMENT: Astaxanthin (2mg)+Lycopene (1.8mg)+D-Alpha-Tocopherol (10IU)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers
Status: COMPLETED
Conditions: Kidney Stone
Interventions: DRUG: Empagliflozin 25 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Cariprazine in the Prevention of Relapse of Symptoms in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Placebo|DRUG: Cariprazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Collection and Storage of Tissue and Blood Samples From Patients With Cancer
Status: RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Malignant Solid Neoplasm|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm
Interventions: OTHER: Cytology Specimen Collection Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Muscular Work and Genetic Variants in Strength Gain of Ischiofemoral and Quadriceps
Status: COMPLETED
Conditions: Muscle Strength|Genetics
Interventions: DEVICE: Concentric-eccentric muscular work|GENETIC: Genetic polymorphism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women With Pyelonephritis
Status: NOT_YET_RECRUITING
Conditions: Pyelonephritis in Pregnancy
Interventions: DRUG: Cefuroxime|DRUG: Cefuroxime Axetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates
Status: COMPLETED
Conditions: Parenteral Nutrition-Associated Liver Disease
Interventions: OTHER: Intravenous fat emulsion|OTHER: Restriction of intravenous fat emulsion to 1 gm/kg/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Screening and Intervention Reducing Anxiety in Patients With Implanted Cardioverter Defibrillator (ICD)
Status: COMPLETED
Conditions: ICD|Cognitive Therapy|Anxiety
Interventions: BEHAVIORAL: Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Comparison of Antiplatelet Therapies in Asian Subjects With Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A High-density Microelectrode for Human Neuronal Recordings
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson Disease, Idiopathic
Interventions: DEVICE: DBC (Diagnostic Biochips) Deep Array microelectrode; Intan Electrophysiology recording system; Matlab response recording to behavioral task
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness of Positioning in Preterm Neonates
Status: ENROLLING_BY_INVITATION
Conditions: Premature Baby 26 to 32 Weeks|Preterm Birth
Interventions: OTHER: Positioning in flexion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT