pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intravenous Anesthesia Versus Anesthesia With Volatile Agents in Elective Craniotomy for Tumors
Status: WITHDRAWN
Conditions: Brain Neoplasms
Interventions: DRUG: Propofol + Remifentanil|DRUG: Sevoflurane + Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cryoablation for Benign Gastrointestinal Anastomotic Strictures
Status: UNKNOWN
Conditions: Esophageal Stricture|Duodenal Stricture|Jejunal Stricture|Anastomotic Stricture of Small Intestine
Interventions: DEVICE: Cryotherapy|PROCEDURE: Esophagogastroduodenoscopy with Balloon Dilatation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research to Evaluate a Possible Relation Between Values Obtained After Processing CT Images, Lung Function Tests and the Experience of the Patient During an Exacerbation in COPD Patients.
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: RADIATION: Functional Respiratory Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inhaled Steroids for the Treatment of Early Pediatric Acute Respiratory Distress Syndrome
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Budesonide|DRUG: Placebo|DEVICE: Nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HGP1602 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: HGP1812|DRUG: HGP1602
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corneal Thinning During Topical Bevacizumab Therapy
Status: WITHDRAWN
Conditions: Corneal Neovascularization
Interventions: DRUG: bevacizumab (Avastin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy and Safety of Nal-IRI for Progressing Brain Metastases in Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Metastatic
Interventions: DRUG: Irinotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dental Implants Placed by Using a Drill Guide Versus Non-guided Placement. Follow-up Study
Status: COMPLETED
Conditions: Dental Implant Failure Nos
Interventions: PROCEDURE: Guided placement|PROCEDURE: Non-guided placement|DEVICE: Astra Tech TX implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)
Status: ACTIVE_NOT_RECRUITING
Conditions: Epithelial Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer
Interventions: BIOLOGICAL: IMNN-001|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Whole Blueberry Powder Consumption on Depression in a Central Louisiana Population
Status: COMPLETED
Conditions: Depression|Depression, Anxiety|Inflammation
Interventions: DIETARY_SUPPLEMENT: Freeze Dried Blueberry Powder - 71717|DIETARY_SUPPLEMENT: USHBC Blueberry Placebo Formula #114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Parenteral Insulin|OTHER: Close Observation|DRUG: Oral Insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interventions That Promote Exclusive Breastfeeding
Status: COMPLETED
Conditions: Breastfeeding, Exclusive
Interventions: PROCEDURE: Delayed umbilical clamping and immediate skin-to-skin contact after birth by caesarean section
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vaginal Self-sampling and Human Papillomavirus Testing in Unscreened Women
Status: COMPLETED
Conditions: Cancer Cervix
Interventions: BEHAVIORAL: Group 1 remove self sample kit at gp consulting room or perform pap smear|BEHAVIORAL: Group 2 perform self sample at home or pap smear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Calcium Aspirin Multiple Micronutrients (CAMMS) to Reduce Preterm Birth
Status: WITHDRAWN
Conditions: Preterm Labor|Small for Gestational Age at Delivery|Hypertensive Disorder of Pregnancy|Low Birth Weight|Neonatal Death
Interventions: COMBINATION_PRODUCT: Calcium aspirin multiple micronutrients|DIETARY_SUPPLEMENT: Iron-folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Utilizing a Brain-Computer Interface for Observational Imitation Training to Enhance Upper Limb Motor Recovery Post-Stroke: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Brain-computer interface|DEVICE: Sham brain-computer interface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT
Status: ACTIVE_NOT_RECRUITING
Conditions: Brain Metastases
Interventions: RADIATION: HA-WBRT|RADIATION: HA-SIB-WBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cancer Parenting Program for the Enhancement of the Quality of Life of Patients With Advanced Cancer and Their Children
Status: RECRUITING
Conditions: Parenting|Parent-Child Relations|Cancer|Survivorship|Hematopoietic and Lymphoid System Neoplasm|Malignant Solid Neoplasm
Interventions: OTHER: Educational Intervention|OTHER: Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neoadjuvant Arterial Embolization Chemotherapy Combined PD-1 Inhibitor for Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Neoplasms
Interventions: PROCEDURE: Arterial chemoembolization|DRUG: Tislelizumab Injection|DRUG: XELOX|DIAGNOSTIC_TEST: Pelvic MRI|PROCEDURE: Laparoscopic radical resection of rectal cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Fit With Us Study
Status: NOT_YET_RECRUITING
Conditions: Mobility Limitations|Disability Physical|Telehealth|Health Coaching|Physical Activity|Behavior, Health|eHealth|Health Literacy|Self Efficacy|Fatigue|Usability|Predictive Model
Interventions: BEHAVIORAL: asynchronous content only|BEHAVIORAL: Asynchronous content and health coaching and no live training|BEHAVIORAL: asynchronous content only and 1 on 1 live training|BEHAVIORAL: asynchronous content and health coaching and 1 on 1 training|BEHAVIORAL: asynchronous content and group training|BEHAVIORAL: Asynchronous content and health coaching and group training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Everolimus|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cutaneous Iontophoresis of Iloprost and Treprostinil in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: treprostinil|DRUG: iloprost|DRUG: NaCl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Zygomatic Versus Conventional Dental Implants in Augmented Maxillae
Status: WITHDRAWN
Conditions: Edentulous Maxilla|Resorbed Maxilla|Implant Therapy
Interventions: DEVICE: Zygomatic implant placement|DEVICE: conventional implants and augmentation of maxilla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: DEVICE: Restrata®|DEVICE: Wound Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Assess the Efficacy and Safety of Ceftriaxone in Patients With Mild to Moderate Parkinson's Disease Dementia
Status: RECRUITING
Conditions: Parkinson's Disease Dementia
Interventions: DRUG: Ceftriaxone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study Evaluating the Efficacy of Hypnosis in Nuclear Medicine
Status: RECRUITING
Conditions: Cancer|Myocarditis|Alzheimer Disease|Parkinson
Interventions: OTHER: Ericksonian Hypnosis|OTHER: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Post-prandial Glucose and Insulin Levels in Type 2 Diabetes Mellitus Patients After Consumption of Ready-to-eat Mixed Meals
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: ready to eat mixed meal 1|OTHER: ready to eat mixed meal 2|OTHER: ready to eat mixed meal 3|OTHER: oral glucose load
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 2 Study in Adults Sensitized to Short Ragweed
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: Standardized Allergenic Extract, Short Ragweed (Ambrosia artemisiifolia)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vibration Response Imaging in the Diagnosis of Pulmonary Disease
Status: COMPLETED
Conditions: Respiratory Diseases|Pulmonary Diseases|Thoracic Diseases|Lung Diseases
Interventions: DEVICE: Vibration Response Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Evaluation of a New Form of Cancer Therapy (Atavistic Chemotherapy) Based on the Principles of Atavistic Metamorphosis (2011)
Status: UNKNOWN
Conditions: Neoplasms
Interventions: DRUG: Anti-Bacterial Agents|DRUG: Anti-Fungal Agents|DRUG: Anti-Protozoal Agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dynamic Pulmonary Vascular Resistance in Patients With Closed Ventricular Septal Defect
Status: COMPLETED
Conditions: Pulmonary Vascular Disease
Interventions: OTHER: The intervention is performing an exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Program of Exercise, Diet and Control of Psychological Stress in Cancer Survivors
Status: COMPLETED
Conditions: Cancer Survivors
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Exercise + Diet counseling|BEHAVIORAL: Exercise + Diet counseling + psycho-emotional support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Effectiveness of Fish Oil Supplements at Reducing the Recurrence of Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Fish oil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Glycemic Control in Obese Diabetics Using Three Different Pen Needles
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DEVICE: 4 mm x 32G Pen Needle|DEVICE: 8mm x 31G Pen Needle|DEVICE: 12.7mm x 29G Pen Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Influence of an Intervention on Diet, Physical Exercise and Mindfulness in the Quality of Life of Survivors With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Nutrition Related Cancer|Physical Activity|Mindfulness
Interventions: OTHER: Mediterranean diet, physical exercise and mindfulness workshops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body
Status: COMPLETED
Conditions: Advanced Solid Tumors|Pharmacokinetics of 14C-OSI-906
Interventions: DRUG: radio-labeled OSI-906|DRUG: OSI-906
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cognitive Behavior Therapy for Treating Anxiety in People With Dementia
Status: COMPLETED
Conditions: Anxiety Disorders|Dementia
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy of Anxiety in Dementia (CBT-AD)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Intermittent Hypoxia in Persons With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Intermittent Hypoxia|OTHER: Sham Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Advanced or Metastatic Cancer of the Esophagus
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|DRUG: paclitaxel|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Treatment Safety and Quality of Life in Patients Receiving Etanercept Biosimilar for Autoimmune Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis
Interventions: DRUG: Etanercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study With Heparin Sodium in Subcutaneous Administration
Status: SUSPENDED
Conditions: Heparin
Interventions: BIOLOGICAL: Sodium Heparin UQ subcutaneous drug administration|BIOLOGICAL: Sodium Heparin FK subcutaneous drug administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparing Cardiac Output Measurements Using a Wearable, Wireless, Non-invasive PPG-Based Device to a Swan Ganz Catheter
Status: COMPLETED
Conditions: Cardiac Output, Low|Cardiac Output, High|Congestive Heart Failure
Interventions: DEVICE: non-invasive monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PCO-02 - Safety and Pharmacokinetics Trial
Status: UNKNOWN
Conditions: Healthy Volunteers
Interventions: DRUG: Bepecin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Study to Evaluate the Safety, Tolerability and the Concentration of the BDP (Beclomethasone Dipropionate), Active Metabolite of BDP, FF( Formoterol Fumarate) and GB (Glycopyrronium Bromide), After Inhalation of CHF 5993 at Two Different Doses and QVAR®
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Test product (T):CHF 5993 BDP/FF/GB 200/6/12.5 µg pMDI|DRUG: Reference product 1 (R1): CHF 5993 BDP/FF/GB 100/6/12.5 µg pMDI|DRUG: Reference product 2 (R2): BDP HFA (QVAR REDIHALER®, BDP 80 μg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of mXELIRI Regimen and FOLFIRI Combined Bevacizumab Regimen as First-line Chemotherapy Regimen for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Capecitabine|DRUG: Irinotecan|DRUG: 5-FU|DRUG: CF|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MOM's PAIN (Methylene Blue for Oral Mucositis' PAIN)
Status: COMPLETED
Conditions: Malignant Neoplasm|Oral Pain|Stomatitis
Interventions: OTHER: Best Practice|DRUG: Methylene Blue|DRUG: Methylene Blue|DRUG: Methylene Blue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamic Evaluation of Linezolid Administered Intravenously in MRSA-positive, Morbidly Obese Patients With Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Impact of Early Intensive Stimulation on Bimanual Function in Infants at High Risk of Unilateral CP (BB-BIM)
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: Early Intensive Bimanual Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VivaSight Double Lumen Tube for Single Lung Ventilation
Status: COMPLETED
Conditions: Double Lumen Endotracheal Tube|Single Lung Ventilation
Interventions: DEVICE: Conventional Double Lumen Tube|DEVICE: VivaSight Double Lumen Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Treatment for Painful Diabetic Neuropathy
Status: NOT_YET_RECRUITING
Conditions: Painful Diabetic Neuropathy
Interventions: DEVICE: Active Controlled Transcranial Magnetic Stimulation (cTMS)|DEVICE: Sham Controlled Transcranial Magnetic Stimulation (cTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
Status: RECRUITING
Conditions: Age-Related Osteoporosis
Interventions: DRUG: Teriparatide|DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echinacea Junior vs Vitamin C in Children 4-12 Years Old
Status: COMPLETED
Conditions: Respiratory Tract Infection Viral
Interventions: DRUG: Echinaforce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Ablative Radiotherapy With Nivolumab for Early-Stage Operable Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer Stage I
Interventions: COMBINATION_PRODUCT: nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Bulk Fill Composite Restorations Associated to Universal Adhesive System
Status: ACTIVE_NOT_RECRUITING
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: PROCEDURE: SEE Strategy and Incremental Restoration|PROCEDURE: SEE Strategy and Bulk Fill Restoration|PROCEDURE: SET Strategy and Incremental Restoration|PROCEDURE: SET Strategy and Bulk Fill Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REPlaCE- Randomized Trial Evaluating the Use of Prothrombin Complex concEntrate to Improve Survival in Patients With Traumatic Coagulopathy
Status: UNKNOWN
Conditions: Coagulopathy|Hemorrhage
Interventions: BIOLOGICAL: Prothrombin Complex Concentrate|BIOLOGICAL: Whole Blood, Plasma, Packed Red Blood Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Celgosivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ARMOR (Analyzing Renal Mechanisms of Creatinine Excretion in Patients On tesaglitazaR)
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tesaglitazar|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Open Label, Multicentre Extension Study of Protocol 42603ATT3002 to Evaluate Safety of Prolonged Release OROS Methlyphenidate in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: double blind placebo|DRUG: double blind PR OROS methylphenidate|DRUG: open label PR OROS methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate TCRT-ESO-A2 Autologous T Cells Expressing TCR Specific for NY-ESO-1 in Subjects With Advanced Solid Tumors
Status: WITHDRAWN
Conditions: Advanced Solid Tumor
Interventions: BIOLOGICAL: TCRT-ESO-A2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Capecitabine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Nucleos(t)ide analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Liposomal Doxorubicin, Bortezomib, Dexamethasone and Lenalidomide for Relapsed/Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: DVD-R
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Ibutamoren on Nonalcoholic Fatty Liver Disease
Status: RECRUITING
Conditions: NAFLD|Nonalcoholic Fatty Liver|NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: LUM-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Inflammation
Interventions: DRUG: Tocilizumab (Actemra®)|DRUG: Other biological agent|DRUG: Corticosteroid and non-biological agents.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Orteronel (TAK-700) in Metastatic or Advanced Non-resectable Granulosa Cell Ovarian Tumors. The Greko II Study.
Status: TERMINATED
Conditions: Metastatic or Advanced Non-resectable Granulosa Cell Ovarian Tumors
Interventions: DRUG: Orteronel 300mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors
Status: RECRUITING
Conditions: Classical Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma (DLBCL)|Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Interventions: BEHAVIORAL: Lifestyles Implemented-Survivorship Care Plan (LS-SCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized, Two-arm, Non-inferiority Study Comparing Endeavor-Resolute Stent With Abbot Xience-V Stent
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Medtronic Endeavor Resolute|DEVICE: Abbott Xience V
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Investigating Immunisation Strategies of DNA, MVA and CN54rgp140 Adjuvanted With GLA-AF to Maximise Antibody Responses
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: DNA|BIOLOGICAL: MVA-C|BIOLOGICAL: CN54rgp140|BIOLOGICAL: GLA-AF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Managing MTBI-related Headaches With rTMS
Status: COMPLETED
Conditions: Traumatic Brain Injury (TBI)
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: D-Cycloserine and Virtual Reality Exposure Therapy
Status: WITHDRAWN
Conditions: Social Anxiety Disorder
Interventions: DRUG: Seromycin|BEHAVIORAL: Virtual Reality Exposure Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: AST-301|DRUG: rhuGM-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Different Concentrations of Localized Injections of Steroids in the Treatment of Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: Triamcinolone acetonide|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Desogestrel Tablets (0.075 mg) Relative to Originator Desogestrel Tablets (0.075 mg)
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Desogestrel-Test product|DRUG: Desogestrel-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparison of Two Different Surgical Techniques for Total Hip Resurfacing
Status: COMPLETED
Conditions: Arthritis|Avascular Necrosis
Interventions: PROCEDURE: Anterolateral approach|PROCEDURE: Posterior approach|DEVICE: ReCap Total Hip Resurfacing|DEVICE: ReCap Total Hip Resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.
Status: COMPLETED
Conditions: Gastric Emptying|Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Cinnamon|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ibrutinib in Relapsed Nodular Lymphocyte-predominant Hodgkin Lymphoma (NLPHL)
Status: COMPLETED
Conditions: Nodular Lymphocyte-Predominant Hodgkin's Lymphoma
Interventions: DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis
Status: UNKNOWN
Conditions: Ulcerative Colitis|Colorectal Cancer|Crohn Disease|Familial Adenomatous Polyposis|Crohn Colitis|Ileal Pouch
Interventions: DIAGNOSTIC_TEST: ICG-NIRF Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Physical Exam Indicated Cerclage in Twin Gestations
Status: TERMINATED
Conditions: Twin Pregnancy, Antepartum Condition or Complication|Preterm Birth|Cervical Dilation Premature
Interventions: PROCEDURE: Physical exam indicated cerclage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA
Status: COMPLETED
Conditions: Staphylococcal Skin Infections
Interventions: DRUG: Daptomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol
Status: TERMINATED
Conditions: Hyperlipidemia
Interventions: DRUG: Evacetrapib|DRUG: Atorvastatin|DRUG: Ezetimibe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Gastric Cancer|Recurrent Pancreatic Cancer|Recurrent Rectal Cancer|Stage III Colon Cancer|Stage III Gastric Cancer|Stage III Pancreatic Cancer|Stage III Rectal Cancer|Stage IV Colon Cancer|Stage IV Gastric Cancer|Stage IV Pancreatic Cancer|Stage IV Rectal Cancer
Interventions: OTHER: laboratory biomarker analysis|OTHER: enzyme-linked immunosorbent assay|OTHER: flow cytometry|OTHER: immunoenzyme technique|BIOLOGICAL: modified vaccinia virus ankara vaccine expressing p53
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Quadrivalent Influenza Vaccine Administered Via the Intramuscular Route in Children and Adolescents in Taiwan
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Quadrivalent Influenza Vaccine (split virion, inactivated)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Gynostemma Pentaphyllum Tea in Insulin Sensitivity in Type 2 Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Gynostemma Pentaphyllum tea|DIETARY_SUPPLEMENT: Placebo tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of S6G5T-3 in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: S6G5T-3|DRUG: S6G5T-8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Calcium+Calcitriol Versus PTH for the Prevention of Hypocalcemia in Thyroidectomy. Randomized Clinical Trial
Status: UNKNOWN
Conditions: Thyroid Cancer|Goiter|Thyroiditis|Hyperthyroidism
Interventions: DIAGNOSTIC_TEST: calcium correction according to PTH levels|DRUG: routine postoperative calcium and calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Gut Microbiota in Mood Disorders in Lebanese Population
Status: RECRUITING
Conditions: Gut Microbiome|Mood Disorders
Interventions: DRUG: Cerebiome|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Safety and Immunogenicity of an Intranasal Vaccine for Respiratory Syncytial Virus in Seropositive Children
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: Investigational RSV vaccine MV-012-968 (Dosage 1)|BIOLOGICAL: Investigational RSV vaccine MV-012-968 (Dosage 2)|OTHER: Placebo|BIOLOGICAL: Investigational RSV vaccine MV-012-968 (Dosage 3)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Drug-drug Interaction Study of Gefitinb on Apatinib in NSCLC Patients
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Apatinib Mesylate, Gefitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Supporting Women With Breast Cancer to Practice DIBH at Home Before Radiation Therapy
Status: NOT_YET_RECRUITING
Conditions: Health Literacy|Distress, Emotional|Preparedness|Mobile Application
Interventions: OTHER: mobile application with breathing instructions and a sensor to attach around the chest. To be able to train at home before radiotherapy with DIBH starts.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics of Terbinafine Hydrogen Chloride (HCl) Nail Lacquer in Patients With Onychomycosis
Status: COMPLETED
Conditions: Onychomycosis/Onycholysis and Tinea Pedis
Interventions: DRUG: Placebo|DRUG: Terbinafine Hydrochloride|DRUG: Terbinafine Hydrochloride|DRUG: Terbinafine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocotrienols for School-going Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DIETARY_SUPPLEMENT: Oral mixed tocotrienols|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction (DDI) Rifabutin
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: BMS-663068|DRUG: Rifabutin|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Rh-Endostatin Combined With CCRT(50 Gy) Followed by Durvalumab Maintenance for the Treatment of Specific Phase III NSCLC
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: Recombinant human endostatin (Endostar)|RADIATION: Thoracic irradiation of 50 Gy with 3DCRT or IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laromustine, Daunorubicin, and Cytarabine in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: amsacrine|DRUG: busulfan|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: laromustine|DRUG: melphalan|DRUG: mitoxantrone hydrochloride|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: autologous hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radioactive Holmium Microspheres for the Treatment of Liver Metastases
Status: COMPLETED
Conditions: Liver Metastasis|Liver Tumors
Interventions: DEVICE: holmium-166 poly lactic acid microspheres|DEVICE: holmium 166 microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Rosuvastatin on the Density Score of Coronary Artery Calcification in CAD Patients With Diabetes Mellitus
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stop Retinal Ganglion Cell Dysfunction Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Glaucoma
Interventions: DRUG: Latanoprost|DRUG: Bimatoprost|DRUG: Travoprost|DRUG: Timolol|DRUG: Dorzolamide|DRUG: Brinzolamide|DRUG: Acetazolamide|DRUG: Methazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability, Bioequivalence and Tolerability of IHL-42X Compared to the Reference Drugs
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: IHL42X|DRUG: Acetazolamide 250 MG|DRUG: Dronabinol 2.5 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Transbronchial Cryobiopsy in Monitoring Complications of Lung Transplantation
Status: NOT_YET_RECRUITING
Conditions: Lung Transplant Rejection
Interventions: PROCEDURE: transbronchial lung cryobiopsy with a 1.1 mm flexible cryoprobe|PROCEDURE: transbronchial lung biopsy with biopsy forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor|Solid Carcinoma|Solid Tumor, Adult|Metastatic Cancer|Advanced Solid Tumor|Cholangiocarcinoma|Bile Duct Cancer
Interventions: BIOLOGICAL: CF33-hNIS|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D Repletion on Small Low Density Lipoprotein (LDL) Particle Number in Subjects at Elevated Cardiovascular Risk
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge
Status: UNKNOWN
Conditions: Bone Resorption|Alveolar Bone Loss|Alveolar Bone Resorption|Bone Graft Failure
Interventions: PROCEDURE: Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)|PROCEDURE: Anorganic Bovine Bone (ABB)|PROCEDURE: Absorbable gelatin sponge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Anti-inflammatory Effect of Prophylactic Macrolides on Children With Chronic Lung Disease
Status: COMPLETED
Conditions: Chronic Lung Disease
Interventions: DRUG: Azithromycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: High-Dose Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Trial for Pixantrone in the FND-R Variant Regimen in Indolent Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Low-Grade|Lymphoma, Small Lymphocytic|Lymphoma, Mixed-Cell, Follicular|Lymphoma, Small Cleaved-Cell, Follicular
Interventions: DRUG: Pixantrone (BBR 2778)|DRUG: fludarabine|DRUG: dexamethasone|DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surveillance in Ulcerative Colitis: Narrow Band Image Versus Chromoendoscopy for High-risk Groups
Status: UNKNOWN
Conditions: Ulcerative Colitis|Dysplasia
Interventions: DIAGNOSTIC_TEST: chromoendoscopy with target biopsy; NBI with target biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Radial Extracorporeal Shock Wave Therapy on Chronic Low Back Pain: a Prospective Controlled Study
Status: UNKNOWN
Conditions: Low Back Pain
Interventions: DEVICE: Radial Extracorporeal Shock Wave Therapy 2000 impulses|DEVICE: Radial Extracorporeal Shock Wave Therapy 4000 impulses
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologically Active Constituents of Chocolate and Their Symptomatic Effects in Patients With Idiopathic Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: Dark chocolate (85% cocoa)|DIETARY_SUPPLEMENT: White chocolate (0% cocoa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Efficacy and Safety of Tacrolimus Drops in Children With Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Vernal Keratoconjunctivitis
Interventions: PROCEDURE: QUICK questionnaire and 6 additional questions|OTHER: Retrospective collection of clinical data from the patients' medical records
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Rifabutin for Treatment of Helicobacter Pylori
Status: UNKNOWN
Conditions: Helicobacter Infections|Resistance Bacterial|Gastritis H Pylori
Interventions: DRUG: Rifabutin|DRUG: Amoxicillin|DRUG: Esomeprazole|DRUG: Clarithromycin|DRUG: Tinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Pharmacokinetics of Subcutaneous Injections With 1 mg/mL, 3 mg/mL, and 10 mg/mL Semaglutide Strengths and the Absolute Bioavailability of Semaglutide
Status: COMPLETED
Conditions: Diabetes|Healthy
Interventions: DRUG: semaglutide|DRUG: semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: sitagliptin phosphate|BEHAVIORAL: Comparator: Diet|BEHAVIORAL: Comparator: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating How the Brain Processes Different Experiences
Status: ENROLLING_BY_INVITATION
Conditions: Anxiety
Interventions: BEHAVIORAL: App-Delivered Mindfulness Training (MT)|BEHAVIORAL: App-Delivered Coloring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Once-Weekly Exenatide Versus Once or Twice Daily Insulin Detemir in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: exenatide once weekly|DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Arterin Cholesterol for Reduction of Lipid Levels
Status: UNKNOWN
Conditions: Blood Cholesterol Lowers|LDL-C
Interventions: DIETARY_SUPPLEMENT: High Dose Arterin Cholesterol|DIETARY_SUPPLEMENT: Low Dose Arterin Cholesterol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER