pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
Status: COMPLETED
Conditions: Nasal Continuous Positive Airway Pressure,|Preterm Infants,|Surfactant Treatment,|Respiratory Distress Syndrome,|Bronchopulmonary Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue
Status: RECRUITING
Conditions: Tongue Neoplasms|Tongue Cancer|Oral Cancer
Interventions: DEVICE: Palatal Augmentation Prosthesis (PAP)|OTHER: Articulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single Supplement of a Standardised Bilberry Extract Modifies Glycaemic Response
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Bilberry capsule first, then control cap|DIETARY_SUPPLEMENT: Control capsule first then bilberry cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Intervals in Real-world Neovascular Age-related Macular Degeneration (nAMD) Patients Switching to Brolucizumab With at Least 12 Months of Follow-up
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of a Multimodal Algorithm for the Treatment of Fecal Incontinence
Status: UNKNOWN
Conditions: Fecal Incontinence
Interventions: COMBINATION_PRODUCT: Biofeedback+Electrostimulation+Kegel|DEVICE: Biofeedback+Tibial Neuromodulation+Kegel|COMBINATION_PRODUCT: Biofeedback+Kegel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease Lipomas
Status: NOT_YET_RECRUITING
Conditions: Dercum's Disease
Interventions: DRUG: CBL-514 injection|DRUG: 0.9% Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: RRx-001 in Second Line Treatment of Advanced Cholangiocarcinoma Prior to Readministration of First-Line Therapy
Status: TERMINATED
Conditions: Cholangiocarcinoma
Interventions: DRUG: RRx-001|DRUG: Gemcitabine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TeleHealth Model to Address Vaccine Hesitancy & Increase Vaccine Completion Among Communities in Southeastern Louisiana
Status: RECRUITING
Conditions: Vaccine Hesitancy
Interventions: BEHAVIORAL: Telehealth: Wellness and Vaccination|BEHAVIORAL: TeleHealth: Wellness Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy of a Counselling and Advisory Care for Health (COACH) Program in Dyslipidemic Patients.
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: OTHER: COACH|OTHER: No intervention for placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcutaneous Electrical Nerve Stimulation During Exercise in Patients With COPD
Status: NOT_YET_RECRUITING
Conditions: COPD|Physical Activity|Rehabilitation|TEN
Interventions: OTHER: CWRT with low frequency transcutaneous electrical nerve stimulation|OTHER: CWRT with sham-low frequency transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PALACE 3: Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: DRUG: Apremilast 20mg|DRUG: Apremilast 30mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emotion Assessment to Study Consciousness in Awakening Patients
Status: RECRUITING
Conditions: Persistent Vegetative State
Interventions: BEHAVIORAL: Physiological recording in response to different types of stimuli|BEHAVIORAL: EEG recording in response to different types of stimuli
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: Ifinatamab Deruxtecan (I-DXd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation the Effectiveness of a Telemonitoring Program in a Cohort of COPD Patient With Frequent Readmissions
Status: COMPLETED
Conditions: COPD
Interventions: DEVICE: telEPOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Micropulse Diode Laser Treatment for Chronic Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Chorioretinopathy
Interventions: PROCEDURE: Subthreshold diode micropulse laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients
Status: NOT_YET_RECRUITING
Conditions: Adverse Effect
Interventions: DRUG: Alpha-Agonist|DRUG: α-adrenergic receptor agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Rehabilitation During Acute Exacerbations of Chronic Obstructive Pulmonary Disease: a Mixed-methods Approach
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Pulmonary Rehabilitation|DRUG: Daily medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of PINTA 745 in End Stage Renal Disease (ESRD) Patients Who Require Hemodialysis and Have Protein Energy Wasting
Status: COMPLETED
Conditions: End Stage Renal Disease|Kidney Disease|Protein Energy Wasting
Interventions: DRUG: PINTA 745|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters
Status: COMPLETED
Conditions: Thrombosis|Venous Thrombosis|Catheter Occlusion
Interventions: DRUG: Alfimeprase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive
Status: COMPLETED
Conditions: Denture Retention
Interventions: DEVICE: Test Product 1|DEVICE: Test Product 2|DEVICE: Reference Product|OTHER: Negative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Preventive Effectiveness of the Individualized Jade Wind-Barrier Herbal Tea Bag on the Common Cold in Elderly With Qi-deficiency Constitution (CCJWBT): A Pragmatic Randomized Controlled Trial
Status: COMPLETED
Conditions: Preventive Effectiveness|Elderly With Qi-deficiency Constitution|The Individualized Jade Wind-Barrier Herbal Tea Bag|Common Cold|Pragmatic Randomized Controlled Trial
Interventions: DRUG: The individualized Jade Wind-Barrier Herbal Tea Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Adaptive Insulin Meal Supervisor (AIMS) in Adults With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Closed Loop with Pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of a Pediatric Lumbar Puncture Restraint Device
Status: UNKNOWN
Conditions: Indication for Lumbar Puncture
Interventions: DEVICE: Pediatric Restraint for Lumbar Puncture|DEVICE: Lumbar Puncture Device|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Perfusion Computer Tomography: Imaging and Clinical Validation Following Reperfusion Therapy in Acute Ischaemic Stroke
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: acetylsalicylic acid, clopidogrel bisulfate and/or warfarin, Apixaban, Rivaroxaban, Dabigatran|DRUG: alteplase|PROCEDURE: endovascular
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Levetiracetam in the Treatment of Patients With Premenstrual Dysphoric Disorder (PMDD)
Status: COMPLETED
Conditions: Premenstrual Dysphoric Disorder
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypertension Related Damage to the Microcirculation in South Asian: Emergence, Predictive Power and Reversibility
Status: UNKNOWN
Conditions: Hypertension|Diabetes|Cardiovascular Disease|Retinopathy
Interventions: BEHAVIORAL: GP training and Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Phase I Study to Assess the Safety and Immunogenicity of Tuberculosis (TB) Vaccine Candidates FP85A and MVA85A
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: FP85A|BIOLOGICAL: MVA85A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Vagus Nerve Stimulation on Post-Aerobic Activity Recovery in Post SARS-CoV-2 Patients
Status: COMPLETED
Conditions: Post-COVID-19 Syndrome
Interventions: DEVICE: non-invasive auricular vagus stimulation|DEVICE: Placebo Non Invasive Vagus Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Significance of Acid Rebound in Functional Dyspepsia
Status: TERMINATED
Conditions: Functional Dyspepsia
Interventions: DRUG: Placebo|DRUG: Pantoprazole + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line
Status: COMPLETED
Conditions: Visual Acuity
Interventions: DEVICE: ACUVUE OASYS® 1-Day for Astigmatism - TAM 24|DEVICE: ACUVUE OASYS® 1-Day for Astigmatism
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Bioequivalence Study Comparing Methylprednisolone Suspension to Methylprednisolone Tablets Under Fed Conditions
Status: WITHDRAWN
Conditions: Therapeutic Equivalency
Interventions: DRUG: methylprednisolone|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti Cytokine Combination Therapy With Daclizumab and Infliximab for Treatment of Steroid Refractory Acute GVHD
Status: COMPLETED
Conditions: Graft vs Host Disease
Interventions: DRUG: daclizumab, infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic RCT of High-dose Oral Montelukast for Moderate and Severe Pediatric Acute Asthma Exacerbations
Status: NOT_YET_RECRUITING
Conditions: Asthma; Status|Asthma in Children|Asthma Acute|Asthma Attack|Acute Asthma Exacerbation
Interventions: DRUG: Montelukast Oral Granules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sedation and Memory Consolidation
Status: COMPLETED
Conditions: Memory Impairment|Amnesia|Recall|Recognition
Interventions: DRUG: Influence of propofol sedation on memory consolidation and 'working memory'|DRUG: Influence of dexmedetomidine sedation on memory consolidation and 'working memory'|DRUG: Influence of spinal anesthesia on memory consolidation and 'working memory'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer
Status: RECRUITING
Conditions: Metastatic Nasopharyngeal Carcinoma|Recurrent Nasopharyngeal Carcinoma|Stage IV Nasopharyngeal Carcinoma AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|DRUG: Carboplatin|DRUG: Cisplatin|PROCEDURE: Computed Tomography|DRUG: Gemcitabine|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Relatlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extracorporeal Shock Wave Therapy Treatment for Nocturnal Leg Cramps
Status: UNKNOWN
Conditions: Nocturnal Leg Cramps
Interventions: DEVICE: Extracorporeal shock wave therapy|PROCEDURE: General physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interactions Between DWC202211 and DWC202212 in Healthy Subjects
Status: ENROLLING_BY_INVITATION
Conditions: Drug-drug Interaction
Interventions: DRUG: DWC202211 100mg|DRUG: DWC202212 5mg|DRUG: DWC202211 100mg + DWC202212 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Loading Doses of Intravenous Bondronat (Ibandronate) in Patients With Breast Cancer and Metastatic Bone Disease.
Status: WITHDRAWN
Conditions: Pain|Bone Neoplasm|Neoplasm Metastasis
Interventions: DRUG: ibandronate [Bondronat]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Surgical Management for Relapse After Conversion Hepatectomy for Initially Unresectable Colorectal Liver Metastasis
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: PROCEDURE: Repeat Liver Surgery|PROCEDURE: Non-Repeat Liver Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase II Trial of Fruquintinib With Sintilimab in Treating Selected Refractory Metastatic Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: Fruquintinib and Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas
Status: RECRUITING
Conditions: Low-grade Glioma
Interventions: DRUG: Tovorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Alzheimer's Disease With CR Plus tDCS in Mild Cognitive Impairment and Depression (PACt-MD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Mild Cognitive Impairment|Major Depressive Disorder, Recurrent, In Remission|Major Depressive Disorder, Single Episode, in Full Remission
Interventions: OTHER: tDCS + CR|OTHER: sham tDCS + sham CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CONCEPT: Comparison of Oxaliplatin vs Conventional Methods With Calcium/Magnesium in First-Line Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitroglycerin as Spasmolytic Regimen for RAS Prevention in Radial Center
Status: UNKNOWN
Conditions: Radial Artery Injury
Interventions: DRUG: NTG 1 MG/ML Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Suprasacral Parallel Shift - Ultrasound/MR Image Fusion Guided Lumbosacral Plexus Block
Status: COMPLETED
Conditions: Hip Fractures|Anesthesia Local|Pain, Perioperative
Interventions: DRUG: Lidocaine-epinephrine added gadoterate meglumine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety of and Immune Response to an HIV Vaccine in Healthy, HIV-Uninfected Adults in Uganda
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA009-00-VP|BIOLOGICAL: Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Validation of Salivary Proteomic Biomarkers for Early Detection of Oral Cancer in Egyptian Population
Status: COMPLETED
Conditions: Oral Cancer
Interventions: DIAGNOSTIC_TEST: histologic evaluation|DIAGNOSTIC_TEST: biochemical analysis|DIAGNOSTIC_TEST: clinical examination
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus
Status: COMPLETED
Conditions: Gestational Diabetes Mellitus in Pregnancy
Interventions: DRUG: Insulin Mixtard|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cystic Fibrosis and Totally Implantable Vascular Access Devices
Status: COMPLETED
Conditions: Cystic Fibrosis|Venous Thrombosis
Interventions: DEVICE: totally implantable vascular access device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Implementation & Feasibility Study of Patients With Dysarthria Following Stroke & Their Carers in Pakistan
Status: UNKNOWN
Conditions: Dysarthria as Late Effect of Stroke
Interventions: OTHER: Group intervention|OTHER: Regular speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Base-in Prism Spectacles for Intermittent Exotropia
Status: COMPLETED
Conditions: Exotropia Intermittent
Interventions: DEVICE: Prism Glasses|DEVICE: Non-Prism Glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section
Status: COMPLETED
Conditions: Pruritus
Interventions: DRUG: Morphine Sulfate|DRUG: Placebo|DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of I-Shape Incısıon Technique on Inter-Implant Papilla: A Prospective Randomized Clinical Trial
Status: COMPLETED
Conditions: Tooth Loss|Bone Loss
Interventions: OTHER: papilla fill index|OTHER: crestal bone loss|OTHER: probing depth|OTHER: Modified sulcus bleeding index|OTHER: Modified plaque index
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Corrected QT Interval Effects of Trastuzumab Emtansine (T-DM1) in Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced or Metastatic Breast Cancer and the Safety and Tolerability of Combined T-DM1 and Pertuzumab in Patients With Early Disease Progression
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BIOLOGICAL: pertuzumab|BIOLOGICAL: Trastuzumab emtansine [Kadcyla]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Remifentanil in NORA
Status: COMPLETED
Conditions: Comparison of the Effects of Remifentanil and Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Bendamustine and Rituximab Induction Chemoimmunotherapy Followed by Maintenance Rituximab (Rituxan®) and Lenalidomide (Revlimid®) in Relapsed and Refractory Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia (CLL)|Small Lymphocytic Lymphoma (SLL)
Interventions: DRUG: Bendamustine and Rituximab Induction followed by Rituximab and Lenalidomide Maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Blood Immune Cell Study of Anakinra Plus Physician's Chemotherapy Choice in Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Anakinra plus Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of HPT Treated Rigid Contact Lenses Made From Hexafocon A
Status: WITHDRAWN
Conditions: Ametropia
Interventions: DEVICE: HPT treatment|DEVICE: untreated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of MORAb-003 in Women With Ovarian Cancer Who Have Relapsed After Platinum-Based Chemotherapy
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Neoplasms
Interventions: DRUG: Farletuzumab|DRUG: Chemo Plus Far
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH
Status: COMPLETED
Conditions: Prostatic Neoplasms|Prostate Disease|Prostate Obstruction|Prostate Hypertrophy
Interventions: DRUG: Single dose tamsulosin 0.4mg|DRUG: Double dose tamsulosin 0.4mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Combination of Multiparametric MRI and Electrophysiology for the Development of New Biomarkers in Spinal Cord Diseases
Status: COMPLETED
Conditions: Spinal Cord Disease
Interventions: PROCEDURE: Combination of multiparametric MRI and electrophysiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma
Status: COMPLETED
Conditions: Alveolar Childhood Rhabdomyosarcoma|Embryonal Childhood Rhabdomyosarcoma|Previously Treated Childhood Rhabdomyosarcoma|Previously Untreated Childhood Rhabdomyosarcoma|Recurrent Childhood Rhabdomyosarcoma
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mediastinal Lymph Node Dissection Versus Spared Mediastinal Lymph Node Dissection in Stage I GGN NSCLC
Status: RECRUITING
Conditions: Lung Neoplasms|Lymph Node Excision
Interventions: PROCEDURE: Systemic mediastinal lymph node dissection|PROCEDURE: Spared mediastinal lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Care, Medication, and Self-Care for Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: PROCEDURE: Chiropractic spinal manipulation|DRUG: Acetaminophen|BEHAVIORAL: Self-care|DRUG: Non-Steroidal anti-inflammatory drugs (NSAIDS)|DRUG: Tylenol with codeine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention
Status: COMPLETED
Conditions: Urinary Tract Infections|Recurrent Urinary Tract Infection
Interventions: DRUG: Intravesical aminoglycoside instillations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin/Metformin HCl 50/850 mg film-coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effects Of Low Intensity Training With Blood Flow Restriction In Rheumatoid Arthritis Patients
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: OTHER: High intensity resistance training|OTHER: Low intensity resistance training combined with blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Psychotherapy Programs to Treat Panic Disorder
Status: COMPLETED
Conditions: Anxiety Disorders|Panic Disorder|Agoraphobia
Interventions: BEHAVIORAL: Cognitive behavioral therapy|BEHAVIORAL: Applied relaxation training (ART)|BEHAVIORAL: Panic focused psychodynamic psychotherapy (PFPP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Molecular Epidemiology of Epidermal Growth Factor Receptor (EGFR) Mutations in Patients With Advanced EGFR Mutation-positive Non-small Cell Lung Cancer Treated With Afatinib
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|EGF-R Positive Non-Small Cell Lung Cancer|EGFR Gene Mutation
Interventions: DRUG: Afatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mass Balance Recovery, Metabolite Profile, and Metabolite Identification of [14C]-Paxalisib in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-Paxalisib Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Physical Exercise on Glucose Control in People With Prediabetes (GLYCEX) - Phase II
Status: NOT_YET_RECRUITING
Conditions: PreDiabetes
Interventions: BEHAVIORAL: 5 days/ week|BEHAVIORAL: 3 days/ week|BEHAVIORAL: 2 days/ week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-VEGFR Vaccine Therapy in Treating Patients With Neovascular Maculopathy
Status: COMPLETED
Conditions: Neovascular Maculopathy|Age Related Macular Degeneration
Interventions: BIOLOGICAL: VEGFR1 and VEGFR2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gemcitabine ± Erlotinib and DN-101 Versus Gemcitabine ± Erlotinib and Placebo in Patients With Advanced Pancreatic Cancer
Status: SUSPENDED
Conditions: Pancreatic Cancer
Interventions: DRUG: placebo + gemcitabine + erlotinib|DRUG: Placebo + gemcitabine|DRUG: calcitriol + gemcitabine|DRUG: calcitriol + gemcitabine + erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess Safety, Tolerability, and Immunogenicity of Influenza Virus Vaccine, Trivalent, Types A and B, Live Cold-adapted (CAIV-T) in Healthy Children
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: CAIV-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Application of Cholangiojejunostomy in the Surgical Treatment of Cholelithiasis With Moderate Dilatation of Common Bile Duct
Status: UNKNOWN
Conditions: Cholangiojejunostomy|Cholelithiasis
Interventions: PROCEDURE: cholangiojejunostomy|PROCEDURE: hepatectomy|DEVICE: T-tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Losartan in the Treatment of NAFLD in Children
Status: COMPLETED
Conditions: NAFLD
Interventions: DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Immunogenicity of HuL001
Status: RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: HuL001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Theta Burst Stimulation Over the Left DLPFC on Language Switching
Status: COMPLETED
Conditions: Languages
Interventions: DEVICE: Sham iTBS|DEVICE: Sham cTBS|DEVICE: intermittent theta burst stimulation (iTBS)|DEVICE: continuous theta burst stimulation (cTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Metabolic Response in Locally Advanced Esophageal Cancer Undergoing Induction Chemoradiotherapy
Status: COMPLETED
Conditions: Esophageal Carcinoma (Squamous Cell Carcinoma - Adenocarcinoma)
Interventions: OTHER: 18-FDG-PET-CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate How Well Single and Multiple Doses of GLPG3667 Are Tolerated in Healthy, Adult Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG3667|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Comparing Efficacy of Treatments for Hidradenitis Suppurativa
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Clindamycin & Rifampin|PROCEDURE: Clindamycin + Rifampin along with NdYag Laser treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selumetinib (AZD6244, ARRY-142886) J-BTC Phase 1 Study
Status: TERMINATED
Conditions: Inoperable Locally Advanced or Metastatic Biliary Tract Cancer
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Bevacizumab in Combination With NaviFUS System for the Treatment of Recurrent Glioblastoma Multiforme (rGBM)
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma Multiforme|Glioblastoma|Glioma|Brain Tumor|Neoplasms|Neoplasms, Nerve Tissue
Interventions: DEVICE: NaviFUS System|DRUG: Lumason|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of the Osia 3 Sound Processor Compared With the Osia 2 Sound Processor in Adult Osia Implant Users
Status: RECRUITING
Conditions: Hearing Loss, Mixed Conductive-Sensorineural|Hearing Loss, Conductive
Interventions: DEVICE: Cochlear Osia 3 Sound Processor|DEVICE: Cochlear™ Osia® 2 Sound Processor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Chronic Abdominal Pain in Pediatric Patients Due to Small Intestinal Bacterial Overgrowth?
Status: COMPLETED
Conditions: Chronic Abdominal Pain|Small Intestinal Bacterial Overgrowth
Interventions: PROCEDURE: Lactulose Breath Test|DRUG: xifaxan|DRUG: placebo|PROCEDURE: Lactulose Breath Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LTAP Block in Endometriosis Surgery - a Randomised Controlled Double-blind Trial
Status: COMPLETED
Conditions: Endometriosis; Peritoneum|Postoperative Pain
Interventions: PROCEDURE: Postoperative pain management: LTAP block or local wound anesthesia with levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sequential Therapies With Sunitinib and Sorafenib in Advanced Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Sorafenib-sunitinib|DRUG: Sunitinib-sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Plus Gemcitabine in Metastatic Breast Cancer Patients After Receiving Taxane Therapy
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms
Interventions: DRUG: Pemetrexed|DRUG: Gemcitabine|DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Regularization in Atrial Fibrilation and Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Atrial Fibrillation
Interventions: DEVICE: Conduction System Pacing (pacemaker implantation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manipulation of Arterial Pressure in Acute Ischemic Stroke
Status: UNKNOWN
Conditions: Stroke, Acute
Interventions: DRUG: Esmolol, Sodium Nitroprussiate (NPS) or Norepinephrine (NOR)|DRUG: Esmolol, NPS or NOR|DRUG: manipulation of SAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Ambroxol Hydrochloride of Soft Pastilles Compared to Ambroxol Hydrochloride Syrup in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ambroxol hydrochloride - soft pastille|DRUG: Ambroxol hydrochloride - syrup - low dose|DRUG: Ambroxol hydrochloride - syrup - high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of ABSOLVE in Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: RhPDGF-BB|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ultra-short-term Treatment of Patients With Iron Deficiency or Anemia Undergoing Adolescent Scoliosis Correction
Status: ACTIVE_NOT_RECRUITING
Conditions: Ultra-short-term|Iron Deficiency Anemia|Scoliosis Idiopathic
Interventions: DRUG: Placebo|DRUG: ferric carboxymaltose , α erythropoietin, vitamin B12, oral folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Fexofenadine HCl 180 mg + Pseudoephedrine HCl 240 mg ER Tablets of Dr. Reddy's and Allegra D 24 Hour ER Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fexofenadine HCl + Pseudoephedrine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Discovery of Biomarkers of Intake of of Highly Consumed Foods in Mexico
Status: ACTIVE_NOT_RECRUITING
Conditions: Nutrition, Healthy|Diet Habit|Diet, Healthy|Dietary Exposure
Interventions: OTHER: Mango Ataulfo|OTHER: Avocado Hass|OTHER: Nopal|OTHER: 3 corn tortilla|OTHER: Guava|OTHER: Amaranth|DIETARY_SUPPLEMENT: Control Beverage (Supportan Drink ® Capuccino)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: cisplatin|DRUG: lomustine|DRUG: vincristine sulfate|PROCEDURE: adjuvant therapy|RADIATION: iodine I 131 monoclonal antibody 3F8|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Validate the Cumulative Life Course Impairment (CLCI) Instrument (DermCLCI-p) in Adult Participants With Moderate to Severe Chronic Plaque Psoriasis (PsO)
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Angiotensin Receptor Blockers in Aortic Stenosis
Status: RECRUITING
Conditions: Aortic Stenosis
Interventions: DRUG: Angiotensin Receptor Blockers|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Neurofilaments and GFAP in Atypical Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing Remitting Multiple Sclerosis|Progressive Multiple Sclerosis|Controls|Multiple Sclerosis
Interventions: OTHER: Blood withdrawal|OTHER: MRI|OTHER: Neurologic / neuropsychologic tests - Patients|OTHER: Neurologic / neuropsychologic tests - Controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Montelukast Compared With Placebo and Salmeterol in Exercise-Induced Bronchoconstriction (0476-316)
Status: COMPLETED
Conditions: Asthma, Exercise-Induced
Interventions: DRUG: Comparator: Montelukast|DRUG: Comparator: Salmeterol|DRUG: Comparator: Placebo (montelukast)|DRUG: Comparator: Placebo (salmeterol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial
Status: RECRUITING
Conditions: Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Interventions: DRUG: Memantine Hydrochloride Oral Solution|DRUG: Trazodone Hydrochloride oral solution|DRUG: Placebo oral solution|DRUG: Amantadine Hydrochloride Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is it Feasible?: Self-Affirmation for Hereditary Breast and Ovarian Cancer Genetic Counseling
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Self Affirmation (SA)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD
Status: TERMINATED
Conditions: Age Related Macular Degeneration (AMD)|Macular Degeneration|Choroidal Neovascularization (CNV)
Interventions: DRUG: Pegaptanib Sodium 0.3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.
Status: COMPLETED
Conditions: Seizures
Interventions: DRUG: Carbamazepine|DRUG: Gabapentin|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Phase I Trial Evaluating the Safety and Pharmacokinetics of Oxfendazole
Status: COMPLETED
Conditions: Neurocysticercosis
Interventions: DRUG: Oxfendazole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Clinical Trial of TENA Identifi in the Nursing Home Setting
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Care planning using TENA Identifi sensor wear data|OTHER: Care planning without using TENA Identifi sensor wear data
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapy of Relapsed AML With Chemotherapy and Dendritic Cell Activated Lymphocytes
Status: WITHDRAWN
Conditions: Acute Myelogenous Leukemia|Chronic Myelogenous Leukemia
Interventions: BIOLOGICAL: Dendritic Cell Activated Lymphocyte
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXT
Status: COMPLETED
Conditions: HIV|AIDS|Kaposi's Sarcoma|Human Herpesvirus 8
Interventions: DRUG: Generic HAART Triomune : d4T, 3TC, NVP|DRUG: Generic HAART Triomune : d4T, 3TC, NVP and chemotherapy ABV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Root Canal Curvatures of the Permanent Mandibular First and Second Molars in a Sample of Egyptian Population Using CBCT
Status: UNKNOWN
Conditions: Prevalence of Curvatures in Root Canals|Direction of Curvatures in Root Canals|Severity of Curvatures in Root Canals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of the Pentax AWS® With the Macintosh Laryngoscopic Intubation in Obstructive Sleep Apnea Syndrome Patients
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Pentax-AWS (AWS; Pentax Corporation, Tokyo, Japan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Chronic Airway Disease, Mucus Rheology and Exacerbations
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Azithropycin according to symptoms|DRUG: Azithromycin according to rheology or symptoms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of CMX001 for the Prevention of CMV Infection in CMV-seropositive HCT Recipients
Status: COMPLETED
Conditions: CMV
Interventions: DRUG: Brincidofovir|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Her2-positive Lung Cancer Treated With Dedicated Drug
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer Metastatic|Non Small Cell Lung Cancer Stage III|HER2 Gene Mutation
Interventions: DRUG: pertuzumab + trastuzumab + docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: labeled ferrous fumarate|DIETARY_SUPPLEMENT: labeled ferrous fumarate + prebiotics|DIETARY_SUPPLEMENT: labeled ferrous sulfate + prebiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Paravertebral Block Using a Multi-orifice Catheter on Preventing Acute and Chronic Post-thoracotomy Pain
Status: COMPLETED
Conditions: Acute Postthoracotomy Pain|Chronic Postthoracotomy Pain|Hypotension After Bolus Dose
Interventions: PROCEDURE: paravertebral block|PROCEDURE: thoracic epidural analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT