pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: An Intervention Study Evaluating the Effects of a Raspberry Leaf Extract in an Osteoarthritic Population.
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DIETARY_SUPPLEMENT: Raspberry Leaf Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: 4 Week Switch Study in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863|DRUG: rhEPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suprachoroidal Injection of CLS-TA Alone or With Aflibercept in Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: IVT Aflibercept|DRUG: SC CLS-TA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Matrix and Genetic Variability as Determinants of Bioavailability and Biological Effects of Beta-cryptoxanthin and Phytosterols
Status: COMPLETED
Conditions: Hypercholesterolemia|Osteoporosis
Interventions: DIETARY_SUPPLEMENT: b-cryptoxanthin plus phytosterols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess Bioequivalence of Fezolinetant Formulations in Healthy Female Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: fezolinetant - test formulation|DRUG: fezolinetant - reference formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CatHeter Ablation of perSistEnd Atrial Fibrillation: Pulmonary Vein Isolation Versus Defragmentation. The CHASE-AF Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: PROCEDURE: PVI alone|PROCEDURE: PVI + Defragmentation + linear lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spencer's Muscle Energy Technique Along With Strain Counter Strain in Adhesive Capsulitis.
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: OTHER: Spencer Muscle energy technique with conventional Physiotherapy|OTHER: Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intralesional Bleomycin Alone and in Combination With Dexamethasone in Infantile Haemangiomas
Status: COMPLETED
Conditions: Comparison of Efficacy of Sclerotherapy in Infantile Hemangioma
Interventions: DRUG: Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daunorubicin Hydrochloride, Cytarabine and Oblimersen Sodium in Treating Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Secondary Acute Myeloid Leukemia|Untreated Adult Acute Myeloid Leukemia
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addition of Vismodegib to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer Patients
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: vismodegib|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endurant Evo International Clinical Trial
Status: TERMINATED
Conditions: Abdominal Aortic Aneurysm|AAA
Interventions: DEVICE: Endurant Evo AAA Stent Graft System|PROCEDURE: Endovascular aneurysm repair (EVAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Cobimetinib in Combination With Atezolizumab and Bevacizumab in Participants With Gastrointestinal and Other Tumors
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab|DRUG: Cobimetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Psychophysiological Response to Aversive Stimuli Over Time With Omega-3
Status: COMPLETED
Conditions: Conduct Disorder|ADHD|Oppositional Defiant Disorder
Interventions: DIETARY_SUPPLEMENT: Omega-3|DIETARY_SUPPLEMENT: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BinaxNOW for Evaluating Children for Infection With SARS-CoV-2 (COVID-19)
Status: TERMINATED
Conditions: SARS-CoV2 Infection|COVID-19
Interventions: DIAGNOSTIC_TEST: BinaxNOW Ag Card
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CY-503 for the Treatment of Chemotherapy-refractory Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: CY-503|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Differences in Postprandial Glucose Changes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type II|Overweight or Obesity
Interventions: OTHER: Shake 1 then Shake 2|OTHER: Shake 2 then Shake 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma (MCL)
Interventions: DRUG: Acalabrutinib in combination with BR|DRUG: Acalabrutinib in combination with VR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Lumbar Disc Disease|Lumbar Disc Herniation|Lumbar Radiculopathy|Physical Therapy
Interventions: PROCEDURE: Physical Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: practice muscle activation patterns|BEHAVIORAL: task practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Population Pharmacokinetics of Imipenem in Patients With Ventilator-associated Pneumonia
Status: COMPLETED
Conditions: Ventilator-Associated Pneumonia
Interventions: DRUG: Imipenem|DRUG: Imipenem|DRUG: Imipenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Epidural Nalbuphine for Postcesarean Epidural Morphine Induced Pruritus
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DRUG: nalbuphine|DRUG: nalbuphine|OTHER: NSS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Extracorporeal Shock Wave Therapy on Spasticity
Status: COMPLETED
Conditions: Stroke|Spasticity, Muscle
Interventions: DEVICE: ESWT|DRUG: BoNT A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Management of Hyperglycemia in the ER: A Randomized Clinical Trial of a Subcutaneous Insulin Aspart Protocol Coupled With Rapid Initiation of Basal Bolus Insulin Prior to Hospital Admission Versus Usual Care
Status: WITHDRAWN
Conditions: Diabetes
Interventions: DRUG: aspart insulin|DRUG: Usual care as prescribed by the ED physicians.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Therapy or Individualized Immunosuppression For Lowering Adverse Event Risk
Status: WITHDRAWN
Conditions: Infection|Transplant;Failure,Kidney
Interventions: DRUG: Mycophenolate Mofetil|DRUG: Mycophenolate Mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bacterial Control in Partial Thickness Burns Using Silver-containing Wound Dressings
Status: COMPLETED
Conditions: Burn Wounds - Partial Thickness (2nd Degree)
Interventions: PROCEDURE: aquacel AG hydrofiber versus acticoat burn dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addressing Disparities in Autism Spectrum Disorder Diagnosis Using a Direct-to-home Telemedicine Tool
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Tele-assessment + in-person assessment|BEHAVIORAL: Tele-assessment only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Is Anti-Factor Xa Associated With Outcome in Patients With Critical COVID-19 on Low-Molecular-Weight Heparin?
Status: COMPLETED
Conditions: Covid19|Thromboembolism|Bleeding
Interventions: DRUG: The effect of LMWH|DIAGNOSTIC_TEST: Monitoring frequency of aFXa-levels
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Bupivacaine 0.25% Injectable Solution|DRUG: bupivacaine plus dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Pharmacokinetics of NNC 0129-0000-1003 in Subjects With Haemophilia A
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: turoctocog alfa pegol|DRUG: turoctocog alfa pegol|DRUG: turoctocog alfa pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of TAF vs Other NAs in Patients With LVL
Status: UNKNOWN
Conditions: Chronic Hepatitis b|Cirrhosis Due to Hepatitis B
Interventions: DRUG: Tenofovir alafenamide fumarate|DRUG: Entecavir or Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Analgesia Effect in Different Psycho-emotional Status Patients During Lower Third Molar Surgical Extractions
Status: COMPLETED
Conditions: Pre-emptive Analgesia in Different Psycho-emotional Status Patients
Interventions: DRUG: Ibuprofen 400 mg and Acetaminophen 500 mg|DRUG: Glucose|OTHER: No drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Hemodialysis Filter
Status: RECRUITING
Conditions: Renal Dysfunction|Sepsis|Hemodialysis
Interventions: DEVICE: Ha-330 Hemoperfusion Filter Hemodialysis|DEVICE: Conventional Hemodialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in People With Overweight or Obesity to Test How BI 1820237, BI 456906, or a Combination of Both Affects Brain Activity
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: BI 456906|DRUG: BI 1820237|DRUG: Placebo for BI 1820237|DRUG: Placebo for BI 456906
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: JNJ-38518168|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Dose Pharmacokinetics of GLPG0634 in Elderly Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG0634 100mg capsule once a day for 10 days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preventing Contrast-induced Nephropathy: Evaluating Hydration Strategies and L-carnitine Administration
Status: TERMINATED
Conditions: Acute Kidney Injury|Renal Insufficiency
Interventions: DRUG: Hydration strategy using saline|DRUG: Hydration strategy using sodium bicarbonate|DRUG: L-carnitine|PROCEDURE: Coronarography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Pharmacokinetic and Safety of TRS003 to China-approved Bevacizumab and US-licensed Avastin®
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: TRS003|BIOLOGICAL: China-approved Bevacizumab|BIOLOGICAL: US-licensed Avastin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Preliminary Safety and Efficacy of RRG001 After Vitrectomy in Subjects With Proliferative Diabetic Retinopathy (PDR)
Status: RECRUITING
Conditions: PDR - Proliferative Diabetic Retinopathy
Interventions: DRUG: RRG001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Volumetric Changes in Free Gingival Graft Procedures Taken With Different Techniques
Status: COMPLETED
Conditions: Ndirectly Measuring the Difference Between the Free Gingival Graft and the Free Gingival Unit Via a Scanner
Interventions: PROCEDURE: Free gingival unit, free gingival greft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Dosing at Planned Cesarean Section and Anemia
Status: WITHDRAWN
Conditions: Blood Loss Anemia|Uterine Atony With Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of Erenumab in Patients With Trigeminal Neuralgia
Status: UNKNOWN
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Erenumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of HR18034 in Inguinal Hernia Repair
Status: UNKNOWN
Conditions: Inguinal Hernia Repair
Interventions: DRUG: HR18034|DRUG: Naropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparative Pharmacodynamics and Pharmacodynamics Equivalence of Antareit 800 mg Chewable Tablets and Riopan 800 mg Chewable Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Heartburn|Acid-dependent Diseases of the Gastrointestinal Tract|Symptomatic Treatment of Gastric and Duodenal Ulcers
Interventions: DRUG: Magaldrate|DRUG: Magaldrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of ARRY-334543 and Gemcitabine in Patients With Advanced Cancer and Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Cancer|Pancreatic Cancer
Interventions: DRUG: ARRY-334543, EGFR/ErbB2 inhibitor; oral|DRUG: Gemcitabine, nucleoside analogue; intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MeRes100 in the Treatment of Patient With Coronary Artery Disease.
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: MeRes100 Sirolimus-Eluting BioResorbable Vascular Scaffold System|DEVICE: Xience EES Everolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Topical 5-fluorouracil and Latanoprost in Vitiligo.
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: Latanoprost 0.005% Ophthalmic Solution|DRUG: 5Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: COPE-Co-morbidities, Parkinson's Disease and Exercise
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Physical therapy|BEHAVIORAL: Group Exercise Class|BEHAVIORAL: Home Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Standard Antibiotic Therapy With Oral Probiotics for Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis|Bacterial Vaginitis
Interventions: DIETARY_SUPPLEMENT: probiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tele-rehabilitation for Women With Urinary Incontinence
Status: ENROLLING_BY_INVITATION
Conditions: Urinary Incontinence
Interventions: OTHER: PFM exercises program through the Mobile app in cooperation with the superficial sensor|OTHER: Face-to face PFM exercises program in Healthcare environment|OTHER: PFM exercises program via home-leaflet(without suprevision)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Post COVID-19 Cognitive Impairment
Interventions: DEVICE: Vielight Neuro RX Gamma active device|DEVICE: Vielight Neuro RX Gamma sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV
Status: RECRUITING
Conditions: Acquired Immune Deficiency Syndrome (AIDS)|HIV Infections
Interventions: DRUG: ATV|DRUG: DRV|DRUG: Cobicistat|DRUG: BR|DRUG: F/TAF|DRUG: LPV/r|DRUG: Third Unboosted Drug|DRUG: Cobicistat TOS|DRUG: F/TAF TOS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collect Flow and Ultrasound Images of Coronary Bypass Grafts
Status: NOT_YET_RECRUITING
Conditions: Cardiac Bypass Surgery (CABG)
Interventions: DEVICE: MiraQ systems with Transit Time Flow Measurement (TTFM) and High Frequency Ultrasound (HFUS) probes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Feasibility Study of Combination of State of Art Chemoimmunotherapy, Intensive Central Nervous System Prophylaxis and Scrotal Irradiation to Treat Primary Diffuse Large B-cell Lymphoma of Testis
Status: COMPLETED
Conditions: Large B-cell Diffuse Lymphoma of Testis
Interventions: DRUG: Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone, liposomal cytarabine, methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet
Status: COMPLETED
Conditions: Transfusion-dependent Thalassemia|Non-transfusion-dependent Thalassemia
Interventions: DRUG: Deferasirox dispersable tablet (DT)|DRUG: Deferasirox film coated tablet (FCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PHA-739358 for Treatment of Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Hormone Refractory Prostate Cancer
Interventions: DRUG: PHA-739358|DRUG: PHA-739358
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Listening Effort in Cochlear Implant Users
Status: COMPLETED
Conditions: Sensorineural Hearing Loss|Cochlear Hearing Loss
Interventions: BEHAVIORAL: Pupillometry|BEHAVIORAL: Evaluation of speech comprehension in quiet|BEHAVIORAL: Evaluation of speech comprehension in noise|BEHAVIORAL: MOCA|BEHAVIORAL: auto evaluation of listening effort in quiet|BEHAVIORAL: auto evaluation of listening effort in noise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peers and Technology for Adherence, Access, Accountability, and Analytics
Status: COMPLETED
Conditions: Hypertension|Medication Adherence
Interventions: BEHAVIORAL: Peer Delivery of Medications|BEHAVIORAL: Health Information Technology (HIT) Platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Kneehab 12-week Peri-operative Total Knee Arthroplasty
Status: COMPLETED
Conditions: Knee Osteoarthritis|Disuse Atrophy
Interventions: OTHER: Standard Physiotherapy|DEVICE: Kneehab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Adherence Improvement Fixed-dose Combination of Olostar Tab. in Patients With Hypertension and Dyslipidemia
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: Olostar Tab (olmesartan/rosuvastatin FDC(fixed dose combination))|DRUG: Two separated drugs(ARB(Angiotensin Ⅱ receptor blocker) and statin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influenza Vaccine With Topical Imiquimod in Influenza Vaccine Non-responsive Children
Status: UNKNOWN
Conditions: Influenza
Interventions: DRUG: Fluarix Tetra|DRUG: Imiquimod cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas
Status: COMPLETED
Conditions: Juvenile Pilocytic Astrocytomas|Optic Pathway Gliomas
Interventions: DRUG: Pegylated interferon alpha-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|COPD Exacerbation
Interventions: DEVICE: home ventilators
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effect in Platelet Count of Atorvastatin and N-acetyl Cysteine
Status: COMPLETED
Conditions: Primary Immune Thrombocytopenia
Interventions: DRUG: Atorvastatin 40 Mg Oral Tablet + N-acetylcysteine 400 mg Oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Kinds of Biliary Intestinal Reconstruction in Cholangiectasia
Status: UNKNOWN
Conditions: Postcholecystectomy Syndrome
Interventions: PROCEDURE: improved Warren-type style|PROCEDURE: Roux-en-Y style
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Multicenter Study for Assessment of Efficacy and Safety of Molnupiravir in Adult Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Molnupiravir (Esperavir)|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Hypertension (Idiopathic, Familial or Anorexigen-associated)
Interventions: DRUG: Dichloroacetate Sodium|DRUG: Dichloroacetate Sodium|DRUG: Dichloroacetate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bowel Preparation Before Colonoscopy
Status: TERMINATED
Conditions: Colonoscopy|Bowel Preparation
Interventions: DRUG: Laxabon|DIETARY_SUPPLEMENT: Fresubin Energy drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: First-in-human Single and Multiple Dose Trial of ATR-258
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ATR-258|DRUG: ATR-258|DRUG: ATR-258
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pegasys and Copegus for Asian Patients With Treatment-naive Hepatitis C Genotypes 6, 7, 8, 9
Status: COMPLETED
Conditions: Chronic Hepatitis C|Asian Americans|Novel Genotypes|Treatment
Interventions: DRUG: Pegylated interferon and ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Access the Pharmacokinetics of HMS5552 in Renal Impaired Subjects and Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HMS5552
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot and Feasibility Study of Fecal Microbiota Transplantation for Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn How Effective and Safe Odronextamab is Compared to Standard of Care for Adult Participants With Previously Treated Aggressive B-cell Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: B-Cell Non-Hodgkin Lymphoma (B-NHL)
Interventions: DRUG: Odronextamab|DRUG: Ifosfamide|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Rituximab|DRUG: Dexamethasone|DRUG: Cisplatin|DRUG: Cytarabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic Access
Status: COMPLETED
Conditions: Aortic Valve Stenosis
Interventions: PROCEDURE: CA-TAVR|DEVICE: Amplatzer Duct Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Influenza, Pneumococcal and Hepatitis B Vaccines in IBD Patients Treated With Vedolizumab
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: Pneumococcal Pneumonia vaccine|BIOLOGICAL: Influenza vaccine|BIOLOGICAL: Hepatitis B vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Ghrelin Administration on Dopamine and Effort
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Ghrelin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
Status: TERMINATED
Conditions: Fine Needle Aspiration|Pancreatic Mass
Interventions: DIAGNOSTIC_TEST: EUS-FNA with ROSE|DIAGNOSTIC_TEST: EUS-FNB without ROSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Friction Versus Frictionless Mechanics During Maxillary En-masse Retraction in Adult Patients
Status: UNKNOWN
Conditions: En-masse Retraction , Class I Bimaxillary Protrusion
Interventions: DEVICE: Friction mechanics|DEVICE: Frictionless mechanics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY900014 in Elderly and Younger Adult Participants With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: LY900014|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resting Full-cycle Ratio-guided Step by Step Balloon Dilation
Status: UNKNOWN
Conditions: de Novo Coronary Lesions
Interventions: DEVICE: RFR-guided step by step balloon dilation|DEVICE: Traditional balloon dilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract Cancer
Status: UNKNOWN
Conditions: Biliary Tract Neoplasm
Interventions: DRUG: Oxaliplatin, Irinotecan, S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mating-EFT Smoking Cessation Intervention
Status: UNKNOWN
Conditions: Smoking Cessation|Motivation
Interventions: BEHAVIORAL: Episodic Future Thinking about Mating Opportunities|BEHAVIORAL: Targeted Mating-EFT Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics Of Azithromycin Immediate Release And Extended Release Formulation In Kids With Acute Otitis Media
Status: COMPLETED
Conditions: Acute Otitis Media
Interventions: DRUG: 60 mg/kg azithromycin ER|DRUG: 30 mg/kg azithromycin IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextrose, Steroid, PRP: Choosing the Right Injection for CRS Relief; a RCT
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: injection Dextrose water|DEVICE: USG machine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intellectual Impairment in Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Cognitive Rehabilitation|BEHAVIORAL: Active Neurofeedback Training|BEHAVIORAL: Neurofeedback Training (placebo / Sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Patient Outcomes and Gingival Blood Flow Using Laser Doppler Flowmetry Following the Use of Episil on Free Gingival Graft Donor Sites
Status: COMPLETED
Conditions: Pain From Free Gingival Graft
Interventions: DEVICE: episil wound dressing|DEVICE: PeriAcryl90 wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of MEDI0457 and Durvalumab in Participants With Human Papilloma Virus (HPV) Associated Recurrent/Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Human Papilloma Virus
Interventions: DRUG: MEDI0457|DEVICE: CELLECTRA®5P device|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home
Status: COMPLETED
Conditions: Noninvasive Ventilation|COPD
Interventions: BEHAVIORAL: Web-based education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pretreatment Botulinum Toxin in Head and Neck Cancer Surgery
Status: NOT_YET_RECRUITING
Conditions: Head Neck Cancer|Xerostomia Following Radiotherapy
Interventions: DRUG: OnabotulinumtoxinA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: CY|BIOLOGICAL: GVAX|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes of MICROPURE and PodEye Monofocal Intraocular Lenses
Status: COMPLETED
Conditions: Cataract|Lens Opacities
Interventions: DEVICE: Micropure 1.2.3.|DEVICE: PODEYE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Paclitaxel-eluting Balloons for Below the Knee Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Drug eluting balloon angioplasty|DEVICE: Conventional balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis
Status: UNKNOWN
Conditions: Idiopathic Scoliosis|Post-operative Pain
Interventions: DRUG: Ketamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Followed by Infusion of Partially HLA Matched Unrelated Donor Cells for Patients With AML Who Are Ineligible for Stem Cell Transplantation
Status: UNKNOWN
Conditions: Acute Myeloid Leukaemia
Interventions: BIOLOGICAL: Partially HLA-matched unrelated donor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Addition of Steroids on Duration of Analgesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Fibroids|Adenomyosis
Interventions: DRUG: Triamcinolone|DRUG: Bupivacaine|OTHER: Iohexol contrast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Standard and Alternative Antimonial Dosage in Patients With American Cutaneous Leishmaniasis
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Meglumine antimoniate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Study of TRM-1(TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: TRAIL-R1 mAb (TRM-1;HGS-ETR1)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Postisometric Relaxation Technique in Female Patients With Dyssynergic Defecation
Status: NOT_YET_RECRUITING
Conditions: Constipation - Functional|Pelvic Floor Disorders|Pelvic Floor Dyssynergia
Interventions: OTHER: Reverse Kegel exercise|OTHER: Postisometric Relaxation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for the Treatment of Refractory Alcohol Use Disorder (AUD): Pilot Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Deep Brain Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
Status: RECRUITING
Conditions: Pancreatic Cancer|Renal Cell Cancer|Breast Cancer|Melanoma|Ovarian Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Aldesleukin|BIOLOGICAL: Anti-hCD70 CAR transduced PBL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of RESOLVE: A Waiting Room Intervention for Crisis Clients
Status: UNKNOWN
Conditions: Depression Anxiety Disorder
Interventions: BEHAVIORAL: Waiting Room Intervention|BEHAVIORAL: Treatment as usual.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluating the Protective Effect of Pentoxifylline on Contrast Induced Nephropathy
Status: UNKNOWN
Conditions: Nephropathy
Interventions: DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Contrast-Enhanced CT and MRI in Diagnosing and Staging Liver Cancer Using UNOS Policy
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cancer
Interventions: DRUG: iodinated contrast dye|DRUG: motexafin gadolinium|OTHER: Eovist-enhanced MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diazepam Use With Standard Management for Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Naproxen|DRUG: Placebo|DRUG: Diazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Achilles Tendon Rupture, Comparison Two Different Operative Techniques. Prospective Randomized Controlled Trial. 14 Years Follow-up.
Status: COMPLETED
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: End-to-end suturation without augmentation|PROCEDURE: End-to-end suturation with augmentation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lamotrigine on Cognition in NF1
Status: TERMINATED
Conditions: Neurofibromatosis Type 1
Interventions: DRUG: Lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring
Status: RECRUITING
Conditions: Wound Care|Pressure Ulcer|Venous Ulcer|Surgical Wound|Trauma Wounds|Draining Wound
Interventions: DEVICE: Integra Dermal Regeneration template (IDRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Endometrial Carcinoma|Recurrent Endometrial Adenocarcinoma|Recurrent Endometrial Carcinoma|Recurrent Endometrial Clear Cell Adenocarcinoma|Recurrent Endometrial Endometrioid Adenocarcinoma|Recurrent Endometrial Mixed Cell Adenocarcinoma|Recurrent Endometrial Serous Adenocarcinoma|Recurrent Endometrial Undifferentiated Carcinoma|Recurrent Uterine Corpus Carcinosarcoma|Stage IV Uterine Corpus Cancer AJCC v7
Interventions: PROCEDURE: Biopsy|PROCEDURE: Computed Tomography|OTHER: Fluorine F 18 Tetrafluoroborate|OTHER: Pharmacological Study|PROCEDURE: Positron Emission Tomography|BIOLOGICAL: Recombinant Vesicular Stomatitis Virus-expressing Human Interferon Beta and Sodium-Iodide Symporter|DRUG: Ruxolitinib Phosphate|DRUG: Technetium Tc-99m Sodium Pertechnetate|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium Carbonate and Tretinoin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: tretinoin|DRUG: lithium carbonate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
Status: COMPLETED
Conditions: Weight Gain|Disorder of Bone Density and Structure, Unspecified|Uterine Bleeding
Interventions: DRUG: Depot medroxyprogesterone acetate (DMPA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peginterferon Alfa-2a Plus Ribavirin Plus Amantadine for the Treatment of Hepatitis C Infected Patients
Status: COMPLETED
Conditions: HCV Infection|Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: ribavirin|DRUG: amantadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Cyproterone Acetate + estradiol|DRUG: Levonorgestrel, Ethinyl Estradiol 0.1-0.02Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase 2 Multicenter Randomized Clinical Trial of CNTF for MacTel
Status: COMPLETED
Conditions: Macular Telangiectasia Type 2
Interventions: BIOLOGICAL: Ciliary neurotrophic factor (CNTF)|PROCEDURE: Sham procedure|DEVICE: NT-501 Implant|PROCEDURE: NT-501 Implant procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Education Impact on Rehabilitation of Hospitalized Patients With Pneumonia and COVID-19
Status: RECRUITING
Conditions: Pneumonia Due to COVID-19
Interventions: OTHER: Education program|OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reconstructive Therapy of Peri-implantitis With PDGF-BB (Gem-21)
Status: ACTIVE_NOT_RECRUITING
Conditions: Peri-Implantitis
Interventions: DRUG: Platelet Derived Growth Factor (PDGF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Network Properties as Biomarkers for Non-Invasive Brain Stimulation (NIBS) After Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE