pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety Evaluation in Recurrent Wheezing Attacks
Status: COMPLETED
Conditions: Bronchospasm; Bronchiolitis|Bronchospasm; Bronchitis
Interventions: BIOLOGICAL: Biological vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tract
Status: COMPLETED
Conditions: Kidney Stone|Unexplained Haematuria|Benignant Tumour Mass in the Upper Urinary Tract
Interventions: DRUG: Isoproterenol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Instrumentation With Intracanal Heating and Activation of Sodium Hypochlorite for the Management of Teeth With Periapical Lesions
Status: RECRUITING
Conditions: Heating and Activation of Sodium Hypochlorite
Interventions: DEVICE: a new prototye device that heat and activate sodium hyochlorite (Aseptico)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Testing a Provider-Level Feedback Intervention to Optimize Postoperative Prescribing
Status: COMPLETED
Conditions: Opioid Prescribing
Interventions: BEHAVIORAL: Push reports
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pilot Bioequivalence Study of Pomalidomide
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Pomalidomide 4 MG Oral Capsule|DRUG: Pomalidomide 4 MG Oral Capsule-Pomalyst
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Valsartan Used To Treat Hypertension For Up To 56 Weeks In Children Ages 1 - 5 Years Who Have Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Cabozantinib|DRUG: Atezolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens
Status: COMPLETED
Conditions: Refractive Ametropia
Interventions: DEVICE: LID015385 soft contact lenses|DEVICE: Comfilcon A soft contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Case Management System for Reducing Pediatric Treatment Abandonment
Status: COMPLETED
Conditions: Burkitt Lymphoma|Retinoblastoma|Diffuse Large B-cell Lymphoma
Interventions: OTHER: mNavigator
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single vs Multi-fraction SRS Patients on Immunotherapy
Status: WITHDRAWN
Conditions: Brain Cancer|Brain Metastases
Interventions: RADIATION: Radiosurgery Single Treatment|RADIATION: Radiosurgery Three Treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Does Quality of Life Decline During the COVID-19 Pandemic and Can we Change Behaviour to Improve Poor Quality of Life?
Status: COMPLETED
Conditions: COVID|Quality of Life|Behavior|Social Isolation
Interventions: BEHAVIORAL: Behaviour Change Technique Intervention to Improve Quality of Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of Tisagenlecleucel in Combination With Ibrutinib in r/r Diffuse Large B-cell Lymphoma Patients
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: BIOLOGICAL: Tisagenlecleucel|DRUG: Ibrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Glembatumumab Vedotin in gpNMB-Expressing, Advanced or Metastatic SCC of the Lung
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Lung
Interventions: DRUG: Phase I: Glembatumumab Vedotin|DRUG: Phase II: Glembatumumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Assess the Effect of Itraconazole and Fluconazole on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: selumetinib|DRUG: itraconazole|DRUG: itraconazole|DRUG: selumetinib|DRUG: selumetinib|DRUG: fluconazole|DRUG: fluconazole|DRUG: selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Crizanlizumab Improves Tissue Oxygen Supply Demand Matching in Patients With Sickle Cell Anemia
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: DRUG: Crizanlizumab|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea - Patient Specific Factors, Success Rate and Compliance
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: CPAP|DEVICE: Mandibular Advancing Splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex
Status: COMPLETED
Conditions: Facial Angiofibroma|Tuberous Sclerosis
Interventions: DRUG: rapamycin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Biodentine and Mineral Trioxide Aggregate in Direct Pulp Capping
Status: COMPLETED
Conditions: Patients With Deep Carious Lesions
Interventions: DRUG: Biodentine|DRUG: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Transcranial Electrical Stimulation in MS
Status: COMPLETED
Conditions: Multiple Sclerosis|Cognitive Impairment
Interventions: DEVICE: non-invasive transcranial electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Clinical Response of Total Neoadjuvant Treatment of Two Methods of Long-term or Short-term Chemoradiotherapy in Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Carcinoma
Interventions: RADIATION: Short course radiotherapy with concurrent capecitabine(825mg/m2)|RADIATION: Long course radiotherapy with concurrent capecitabine(825mg/m2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Safety of Clindamycin + Benzoyl Peroxide Formulation With Azelaic Acid Formulation in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Clindamycin + BPO|DRUG: Azelaic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vestibular Depth on Predictability of Miller Class III/ RT2 Gingival Recession Coverage
Status: RECRUITING
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Recession coverage with CTG using minimally invasive access technique in shallow vestibule|PROCEDURE: Recession coverage with CTG using minimally invasive access technique in deep vestibule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Is Kinesio Taping Treatment Effective in Sacroiliac Joint Dysfunction
Status: COMPLETED
Conditions: Sacroiliac Joint Dysfunction
Interventions: OTHER: Kinesio-taping treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SPECTACL: SPECTroscopic Assessment of Coronary Lipid
Status: COMPLETED
Conditions: Angina Pectoris|Angina, Unstable|Myocardial Infarction
Interventions: DEVICE: Near Infrared Spectroscopy (NIRS) Imaging|DEVICE: intravascular ultrasound (IVUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EFFECT:Eccentric Fixation From Enhanced Clinical Training
Status: COMPLETED
Conditions: Age Related Macular Degeneration (ARMD)
Interventions: BEHAVIORAL: Supervised Reading|BEHAVIORAL: EVT at the PRL|BEHAVIORAL: EVT at the TRL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Bias Modification for Perfectionism and Intolerance to Uncertainty
Status: COMPLETED
Conditions: Perfectionism|Intolerance to Uncertainty
Interventions: BEHAVIORAL: Cognitive Bias Modification|BEHAVIORAL: Cognitive Bias Modification for Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study)
Status: WITHDRAWN
Conditions: Cesarean Section|Pain, Acute
Interventions: PROCEDURE: Intrathecal morphine as well as local anaesthetic in Blocks|PROCEDURE: Intrathecal morphine as well as saline in Block|PROCEDURE: Saline intrathecal as well as saline in Blocks|PROCEDURE: Saline intrathecal as well as local anaesthetic in Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)
Status: TERMINATED
Conditions: Lymphoblastic Leukemia, Acute|Lymphoblastic Leukemia, Acute, Childhood|Leukemia, Lymphoblastic, Acute, T Cell|Leukemia, Lymphoblastic, Acute
Interventions: DRUG: EZN-3042|DRUG: Cytarabine|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Vincristine|DRUG: PEG-asparaginase|DRUG: Methotrexate|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementering PTSD Treatment
Status: UNKNOWN
Conditions: Post-traumatic Stress Disorder|Leadership|Implementation
Interventions: BEHAVIORAL: LOCI|BEHAVIORAL: CT-PTSD|BEHAVIORAL: EMDR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Hypofractionated radiotherapy|DRUG: Pembrolizumab infusion|PROCEDURE: Blood and tissue sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Breath, Cell Free DNA and Image Analysis to PRedIct Normal TissUe and Tumour Response During Prostate Cancer SBRT
Status: RECRUITING
Conditions: Prostate Cancer|Radiotherapy Side Effects|Volatile Organic Compounds|DNA Damage
Interventions: RADIATION: Stereotactic Body Radiotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare the Efficacy of GNS561 Versus Standard of Care in Patients With SARS-CoV-2 (COVID-19) Infection
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: GNS561
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shared Decision Making With Breast Cancer Patients
Status: COMPLETED
Conditions: Shared Decision Making|Breast Neoplasms|Radiotherapy, Adjuvant
Interventions: BEHAVIORAL: Shared decision making supported by an in-consultation patient decision aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DEXMEDETOMIDINE in NORMAL VAGINAL DELIVERY
Status: RECRUITING
Conditions: Painless Vainal Labour
Interventions: DRUG: Dexmedetomidine Injection [Precedex]|DRUG: Bupivacaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Conventional Laparoscopic APR Versus Laparoscopic APR With Transabdominal Individualized Levator Transection
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: LAPR|PROCEDURE: LAPR-TILT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Vein of Marshall Ethanol Infusion During Left Atrial Linear Ablation in Patients With Persistent Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: ALINE + VoM infusion|PROCEDURE: ALINE only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diet and Behavior in Young Children With Autism
Status: COMPLETED
Conditions: Autism|Autistic Disorder
Interventions: BEHAVIORAL: Gluten- and casein-free diet|BEHAVIORAL: Placebo controlled diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE Device) in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta (Zone 0/1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm, Thoracic|Aorta, Lesion
Interventions: DEVICE: GORE® TAG® Thoracic Branch Endoprosthesis|PROCEDURE: Revascularization Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Clinical Study to Compare the Efficacy and Safety of DA-3801 and That of Gonal-F®
Status: COMPLETED
Conditions: Infertility|Anovulation
Interventions: DRUG: DA-3801 Injection|DRUG: Gonal-F®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study Of Stage 1 Subjects Of Study A3921009 For The Prevention Of Acute Rejection In Kidney Transplant Patient
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Tacrolimus|DRUG: CP-690,550|DRUG: CP-690,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients
Status: TERMINATED
Conditions: Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: Venglustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokine Adsorption in Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation
Status: COMPLETED
Conditions: Coronavirus|COVID-19|SARS-CoV Infection|Respiratory Failure|Cytokine Storm
Interventions: DEVICE: vv-ECMO + cytokine adsorption (Cytosorb adsorber)|DEVICE: vv-ECMO only (no cytokine adsorption)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Disease|Lung Transplant|Extracorporeal Membrane Oxygenation
Interventions: DEVICE: MRP and NMES(neuromuscular electric stimulation)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Validation of the EuroSCORE II in Open and Trans-catheter Mitral Valve Repair.
Status: COMPLETED
Conditions: Mitral Valve Regurgitation
Interventions: PROCEDURE: Surgical Mitral Valve Repair|PROCEDURE: Transcatheter Mitral Valve Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Consistency Study of GlaxoSmithKline (GSK) Biologicals' MMR Vaccine (209762) (Priorix) Comparing Immunogenicity and Safety to Merck & Co., Inc.'s MMR Vaccine (M-M-R II), in Children 12 to 15 Months of Age
Status: COMPLETED
Conditions: Rubella|Measles|Mumps
Interventions: BIOLOGICAL: Priorix|BIOLOGICAL: M-M-R II|BIOLOGICAL: Varivax|BIOLOGICAL: Havrix|BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Intervention for Employees of the University of Bern
Status: COMPLETED
Conditions: Neck Pain|Musculoskeletal Diseases|Occupational Health|Efficiency|Exercise Therapy|Work Performance|Presenteeism
Interventions: OTHER: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Aerobic Exercise Training on Autonomic Nervous System and Endothelial Function in Patients With Compensated Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Cirrhosis|Aerobic Exercises|Lifestyle Modification|Endothelial Function|Autonomic Nervous System|Autonomic Dysfunction|Heart Rate Variability|Flow Mediated Dilation|Sarcopenia|Physical Activity|Physical Functional Performance
Interventions: BEHAVIORAL: Aerobic exercise|BEHAVIORAL: Nutrition consultant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Caffeine on HRV and Exercise Performance in Spinal Cord Injury
Status: COMPLETED
Conditions: Caffeine|Spinal Cord Injury
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Placebo (Mannitol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes
Status: COMPLETED
Conditions: Impaired Glucose Tolerance
Interventions: DRUG: Exenatide|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Subcutaneous Infusion for Control of Treprostinil Related Site Pain
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REmote iSchemic Conditioning in acUtE BRAin INfarction Study
Status: UNKNOWN
Conditions: Cerebral Infarction
Interventions: DEVICE: Lower limb tourniquet|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Genomic Test Impact on Shared Decision of Adjuvant Chemotherapy in ER-positive, Her2-negative Early Breast Cancer
Status: WITHDRAWN
Conditions: ER-positive Her2-negative Early Breast Cancer
Interventions: DIAGNOSTIC_TEST: Genomic test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Haemodynamic Optimization Using Preload Dependence During Septic Shock = EHOSS-1
Status: COMPLETED
Conditions: Septic Shock
Interventions: DRUG: FLUID MANAGEMENT GUIDED WITH PRELOAD-DEPENDENCE PARAMETERS (VOLUVEN ®)|DRUG: STANDARD-GUIDED FLUID MANAGEMENT (VOLUVEN ®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-arrhythmic Therapy vs Catheter Ablation as First Line Treatment for AICD Shock Prevention
Status: TERMINATED
Conditions: Ventricular Tachycardia|Ventricular Arrhythmia
Interventions: DRUG: Antiarrhythmic Drug Therapy|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Informing the Patient on the Type of Management, Surgical or Functional, After Rupture of the Anterior Cruciate Ligament
Status: RECRUITING
Conditions: Ligament Rupture
Interventions: PROCEDURE: Functional or surgical management in 1st intention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of a Booster Dose of GSK Biological's Boostrix-Polio Vaccine
Status: COMPLETED
Conditions: Poliomyelitis|Diphtheria|Tetanus|Acellular Pertussis
Interventions: BIOLOGICAL: Boostrix-Polio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transmission Reduction Intervention Project
Status: UNKNOWN
Conditions: HIV
Interventions: OTHER: Assays|OTHER: HIV medical care|OTHER: Social network and venue tracing|OTHER: Community alerts|OTHER: Community education|BEHAVIORAL: HIV counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: 5 Versus 10 Sprays of Lignocaine for Pharyngeal Anaesthesia During Bronchoscopy
Status: UNKNOWN
Conditions: Bronchoscopy|Anesthesia, Local
Interventions: DRUG: 5 sprays of 10% lignocaine|DRUG: 10 sprays of 10% lignocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lenalidomide and Low-dose Cyclophosphamide for MALT Lymphoma
Status: UNKNOWN
Conditions: Antibiotics-unresponsive MALT Lymphoma|Relapsed MALT Type Extranodal Marginal Zone B-Cell Lymphoma|Refractory Extranodal Marginal Zone B-Cell Lymphoma (MALT)
Interventions: DRUG: Lenalidomide [Leavdo®]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positive Psychology Interventions in Individuals With Chronic Pain and Spinal Cord Injury
Status: COMPLETED
Conditions: Chronic Pain|Spinal Cord Injury
Interventions: BEHAVIORAL: Positive Psychology intervention|BEHAVIORAL: Positive Psychology intervention (Control exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopically Assisted Anorectal Pull-through Versus Posterior Sagittal Anorectoplasty
Status: UNKNOWN
Conditions: Anorectal Malformation
Interventions: DEVICE: laparoscopic pull-through
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Fuji Type VII Sealant Versus Resin Based Sealant. A Clinical Trial
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: Application of the GIC based sealant|OTHER: Resin based sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Increased Dose of TA-650(Infliximab) in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: TA-650 3 mg/kg|DRUG: TA-650 6 mg/kg|DRUG: TA-650 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celebrex - Cervix: Celecoxib in the Treatment of Patients With Locally Advanced Carcinoma of the Cervix
Status: COMPLETED
Conditions: Cervix Neoplasms
Interventions: DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Hydroxychloroquine for Thrombocytopenia in SLE
Status: TERMINATED
Conditions: Thrombocytopenia
Interventions: DRUG: Hydroxychloroquine|DRUG: Cyclophosphamide|DRUG: Azathioprine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III)
Status: NOT_YET_RECRUITING
Conditions: Venous Leg Ulcer
Interventions: DRUG: allo-APZ2-CVU|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vorapaxar in the Human Endotoxemia Model
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Vorapaxar|DRUG: Placebo|OTHER: LPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Auricular Acupressure and Group Counseling on Smoking Cessation Tobacco Withdrawal Symptoms
Status: TERMINATED
Conditions: Smoking
Interventions: BEHAVIORAL: group counseling|DEVICE: Auricular acupressure|DEVICE: placebo acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Mapping in Patients With Newly Diagnosed Endometrial Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Stage I Endometrial Carcinoma|Stage II Endometrial Carcinoma|Stage III Endometrial Carcinoma|Stage IV Endometrial Carcinoma
Interventions: PROCEDURE: lymph node mapping|PROCEDURE: sentinel lymph node biopsy|DRUG: isosulfan blue|DRUG: indocyanine green solution|PROCEDURE: therapeutic conventional surgery|PROCEDURE: lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Video Education With Result Dependent dIsclosure
Status: RECRUITING
Conditions: Genetic Testing|Breast Cancer|Ovarian Cancer|Pancreatic Cancer|Prostate Cancer|Colorectal Cancer|Renal Cancer|Melanoma|Sarcoma
Interventions: BEHAVIORAL: Video Education|BEHAVIORAL: Genetic Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Deflating the Tracheostomy Tube Cuff and Time for Decannulation
Status: UNKNOWN
Conditions: Deglutition Disorders|Tracheostomy Complication
Interventions: OTHER: Deflate the tracheostomy cuff early|OTHER: Deflate the tracheostomy cuff after complete weaning mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Investigational Pneumococcal Vaccine in Elderly Population
Status: COMPLETED
Conditions: Prophylaxis Invasive Pneumococcal Diseases and Pneumonia
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK513026|BIOLOGICAL: Pneumovax 23™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Copanlisib and Combination Chemotherapy for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Relapsed Grade 3b Follicular Lymphoma
Status: TERMINATED
Conditions: Grade 3b Follicular Lymphoma|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Non-Hodgkin's Lymphoma
Interventions: DRUG: Copanlisib|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Dexamethasone|BIOLOGICAL: Rituximab|BIOLOGICAL: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: imipramine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of Red Flavonoid in Photoaging
Status: WITHDRAWN
Conditions: Photoaging of Skin|Skin Aging
Interventions: PROCEDURE: skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Pursed-lip breathing|BEHAVIORAL: Normal Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development
Status: COMPLETED
Conditions: Cicatrix
Interventions: DRUG: extract of allium cepae, allantoin and heparin|PROCEDURE: Scar excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Invasive Techniques in Trigger Points
Status: UNKNOWN
Conditions: Trigger Point Pain, Myofascial
Interventions: OTHER: Dynamic dry needling|DEVICE: Fixed dose dynamic MEP|OTHER: Static Dry needling|DEVICE: Fixed dose static MEP|DEVICE: Algorithm-based dose static MEP|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study on the Efficacy and Safety of Tanezumab in Patients With Cancer Pain Due to Bone Metastasis Who Are Taking Background Opioid Therapy
Status: COMPLETED
Conditions: Bone Metastasis|Cancer Pain
Interventions: DRUG: Tanezumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Determinants for Therapy Response on Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sunitinib, Pazopanib, Bevacizumab, Everolimus...
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of Sodium Enoxaparin for Venous Thromboembolism in High-Risk Abdominal Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Sodium enoxaparin|DRUG: Sodium Enoxaparin clexane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nasotracheal Suction With Tiemann Catheter Compared to the Classic Technique With the Suction Catheter
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DEVICE: Catheter Tiemann|DEVICE: Suction catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FES-PET for Patients Treated on NCI Protocol 8762
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: Diagnostic Imaging ( 6α-[18F]fluoro-17β-estradiol (FES))
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Naltrexone Therapy: A Novel Treatment for Heroin Dependence
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: depot naltrexone|BEHAVIORAL: Compliance enhancement (CE)|DRUG: BNT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rabbit Anti-thymocyte Globulin in the Treatment of Patients With Low to Intermediate-1 Risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndrome (MDS)
Interventions: BIOLOGICAL: Thymoglobulin®, Rabbit Anti-thymocyte Globulin (rATG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Interventions Increasing Sensory Stimulus in Elderly Patients With Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Dysphagia
Interventions: DEVICE: Transcutaneous electrical stimulation|DIETARY_SUPPLEMENT: TRPV1 agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Derris Scandens Benth Extract VS Naproxen in Knee OA
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Derris scandens Benth extracts|DRUG: naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Oxymorphone Hydrochloride 40 mg Extended Release Tablets Under Fasted Conditions
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: oxymorphone|DRUG: Oxymorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Phenolic Acids on the Human Vasculature
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: OTHER: 43.3 mg hydrolyzed green coffee extract|OTHER: 86.6 mg hydrolyzed green coffee extract|OTHER: 173 mg hydrolyzed green coffee extract|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Impact on Outcome of Early Endoscopic Extraction of Bile Duct Stones in Biliary Pancreatitis
Status: COMPLETED
Conditions: Biliary Pancreatitis
Interventions: PROCEDURE: Endoscopic sphincterotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Model-based Cueing-as-needed for Walking in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease|Walking, Difficulty|Gait, Festinating
Interventions: OTHER: 20-minute gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of CCX 354-C in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CCX 354-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment
Status: RECRUITING
Conditions: Hepatic Impairment|Healthy Volunteers
Interventions: DRUG: Repotrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Value of Linear Ablation Without Pulmonary Vein Isolation in Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation, Persistent|Atrial Fibrillation
Interventions: PROCEDURE: catheter radiofrequency ablation(individualized stepwise linear without pulmonary vein isolation)|PROCEDURE: catheter radiofrequency ablation(PVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Indacaterol 75 μg Compared to Placebo, Assessing Time to Patient's Perception of Onset of Effect in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: indacaterol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Association Between Diabetes Mellitus, Oral Lichen Planus and Insulin-like Growth Factors 1 and 2 (IGF1 and IGF2)
Status: COMPLETED
Conditions: Oral Lichen Planus|Diabetes Mellitus
Interventions: GENETIC: comparative semiquantitative immunohistochemistry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Screening Of CoRonary ArTEry diSease
Status: NOT_YET_RECRUITING
Conditions: Cardiology|Coronary Artery Disease
Interventions: OTHER: Coronary CT in 1st line compared to the strategy with functional test in 1st line in patient at Intermediate Risk of Developing Stable Coronary Disease:
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease|Interstitial Pneumonia|Interstitial Fibrosis|Autoimmune Diseases
Interventions: DIAGNOSTIC_TEST: Bronchoalveolar lavage and taking bronchial mucosa samples|DIAGNOSTIC_TEST: 6minute walk test|DIAGNOSTIC_TEST: Arterial blood gas|PROCEDURE: Blood drawing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: LHA510 Proof-of-Concept Study as a Maintenance Therapy for Patients With Wet Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Exudative Age-Related Macular Degeneration
Interventions: DRUG: LHA510 ophthalmic suspension|DRUG: LHA510 vehicle|DRUG: Ranibizumab ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Centipeda Minima (CM) in Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Centipeda minima+PD-1/PD-L1 inhibitor|DRUG: PD-1/PD-L1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Low-Density Lipoprotein Cholesterol (LDL-C) Reduction Using Evolocumab (AMG 145) in Japanese Patients With Advanced Cardiovascular Risk
Status: COMPLETED
Conditions: Hyperlipidemia or Mixed Dyslipidemia at High Risk for Cardiovascular Events
Interventions: DRUG: Atorvastatin|BIOLOGICAL: Evolocumab|OTHER: Placebo to Evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cold Vapor on Nausea and Vomiting in the Early Postoperative Period After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy|Postoperative Nausea|Postoperative Vomiting
Interventions: OTHER: Cold vapor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Best Available Therapy Versus Autologous Hematopoetic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)
Status: RECRUITING
Conditions: Relapsing Multiple Sclerosis|Relapsing Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|BIOLOGICAL: Best Available Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Opioid Rapid Response System: Naloxone Training in Communities
Status: RECRUITING
Conditions: Opioid Overdose
Interventions: BEHAVIORAL: Opioid Rapid Resonse System (ORRS) training|BEHAVIORAL: Non-active opioid overdose response training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Topical Treatment With Fresh Human Milk Versus Emollient on Atopic Eczema Spots in Young Children
Status: COMPLETED
Conditions: Atopic Eczema
Interventions: OTHER: Human milk and emollient: Apobase creme® (Actavis Norway AS)|OTHER: Emollient: Apobase creme® (Actavis Norway AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Lung Injury Complicating Lung Resection
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: N-acetylcysteine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy.
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Liver resection|PROCEDURE: Locoregional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Immunonutrition for Patients Undergoing CRS and HIPEC
Status: COMPLETED
Conditions: Peritoneal Metastases
Interventions: DIETARY_SUPPLEMENT: IMPACT immunotherapy|DIETARY_SUPPLEMENT: ENSURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Iron Deficiency
Interventions: DRUG: Saline|DRUG: Ferinject or CosmoFer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate Natural Orifice Transvaginal Endoscopic Cholecystectomy With Laparoscopic Assistance
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: DEVICE: NOTES GEN 1 Toolbox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Raltitrexed in Treating Children With Refractory Acute Leukemia
Status: COMPLETED
Conditions: Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia
Interventions: DRUG: raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo Evaluation of Immunity Activation Face to S. Aureus Antigens and Adjuvants of a Vaccine Candidate in Cells From Haemodialysis Patients
Status: COMPLETED
Conditions: Staphylococcus Aureus
Interventions: BIOLOGICAL: blood samples|BIOLOGICAL: nasal swabs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Fascia Iliaca Nerve Block for Post Hip Arthroscopy
Status: WITHDRAWN
Conditions: Hip Surgery Corrective|Anesthesia; Functional
Interventions: PROCEDURE: Drug group Fascia iliaca nerve block|PROCEDURE: Control group sham nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multiple Ascending Dose Study of TD-0714 in Healthy and Elderly Subjects
Status: COMPLETED
Conditions: Healthy Adults, Elderly Subjects
Interventions: DRUG: TD-0714|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brentuximab Vedotin and Lenalidomide in Patients With Relapsed/ Refractory T-cell Lymphoma or Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, T-Cell, Cutaneous|Lymphoma, T-Cell, Peripheral|Hodgkin Lymphoma
Interventions: DRUG: Lenalidomide 15mg|DRUG: Brentuximab Vedotin 1.8 mg/Kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-Term, Open Label Extension Study of Pemziviptadil (PB1046) in PAH Subjects Following Completion of Study PB1046-PT-CL-0004
Status: TERMINATED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Pemziviptadil (PB1046) Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Presurgery Anxiolysis in Children Treated With Hydroxyzine Versus Non-pharmacological Intervention (Distractoria Technique Clown)
Status: TERMINATED
Conditions: Anxiety
Interventions: DRUG: Hydroxyzine|OTHER: Clowns intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT