pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Cancers When First Given Cyclophosphamide
Status: COMPLETED
Conditions: Ovarian Cancer|Colorectal Cancer|Carcinoma, Non-small-cell Lung|Prostate Cancer
Interventions: DRUG: EMD 273066
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety and Efficacy Evaluation of NanoLithium® NP03 in Patients With Mild-to-severe Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease
Interventions: DRUG: NanoLithium® NP03|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Heavy Smoking on Hard and Soft Tissue Parameters Prospective Clinical Trial
Status: RECRUITING
Conditions: Dental Implants,Peri-implantitis,Smoking
Interventions: DEVICE: Neo dental implant Alpha Bio Tec. Ltd.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Serratus Anterior Plane Block Versus Standard of Care After Totally Endoscopic Aortic Valve Replacement
Status: COMPLETED
Conditions: Analgesia|Surgery|Cardiac Disease
Interventions: PROCEDURE: Serratus anterior plane block|DRUG: PCIA with Piritramide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Japanese and Caucasian Subjects to Assess the Pharmacokinetics, Safety and Tolerability of Risankizumab
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Risankizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pragmatic Research on Diuretic Management in Early BPD Pilot
Status: RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Furosemide (plus potassium chloride)|DRUG: Placebo (plus placebo electrolyte solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Prolanta™ in Recurrent or Persistent Epithelial Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Cancer|Peritoneal Cancer|Fallopian Tube Cancer
Interventions: BIOLOGICAL: Prolanta, a human prolactin receptor antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplant in Devic's Disease
Status: COMPLETED
Conditions: Devic's Disease
Interventions: PROCEDURE: Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: G-CSF|DRUG: rATG|DRUG: Mesna|DRUG: Rituximab|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine
Status: NOT_YET_RECRUITING
Conditions: Spinal Tumor
Interventions: DEVICE: 3D-printed custom-made non-rigid biomimetic implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of SUMMIT BRUSH in Treatment of Blepharitis
Status: RECRUITING
Conditions: Blepharitis
Interventions: DEVICE: SUMMIT BRUSH|OTHER: Ocusoft Lid Scrub Original Foaming Eyelid Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Insulin 320 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Healthy
Interventions: DRUG: Insulin 320|DRUG: insulin glargine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Pharmacokinetics and Safety of Vismodegib - OPTIVISMO-1
Status: COMPLETED
Conditions: Metastatic Basal Cell Carcinoma|Locally Advanced Basal Cell Carcinoma
Interventions: DRUG: Treatment with vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Use of a Novel Oral Health Screening Instrument by Caregivers in Nursing Homes
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Health|Old Age; Dementia|Long-Term Care|Nursing Homes|Geriatric Assessment|Mouth Diseases
Interventions: OTHER: OHS-interRAI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Tykerb Evaluation After Chemotherapy (TEACH): Lapatinib Versus Placebo In Women With Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Neoplasms, Breast
Interventions: DRUG: lapatinib|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vancomycin for Primary Sclerosing Cholangitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Sclerosing Cholangitis
Interventions: DRUG: Vancomycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Kidney Graft Function Under the Immunosuppression Strategies
Status: COMPLETED
Conditions: Chronic Renal Disease
Interventions: DRUG: Standard Dose of Myfortic and Reduced Dose of Myfortic|DRUG: Prednisolone OR methylprednisolone OR deflazacort injected both control group and experimental group|DRUG: Basiliximab injected both control group and experimental group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Safety and Efficacy of Heavyweight and Partially Absorbable Mesh in Inguinal Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: Proflex® Mesh Mesh implantation|DEVICE: Marlex® Mesh Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effects of Radial Shock Wave Therapy in the Treatment of Temporomandibular Joint Syndrome.
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Dysfunction Syndrome
Interventions: OTHER: Manual therapy and extracorporeal radial shock waves therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiotherapy for the Treatment of Refractory Ventricular Tachycardia
Status: RECRUITING
Conditions: Radiotherapy; Complications|Ventricular Tachycardia|Structural Heart Abnormality|Heart Failure
Interventions: RADIATION: Stereotactic ablative radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, 5-FU and Leucovorin in Combination With Oral Capecitabine for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: chemotherapy (capecitabine, oxaliplatin, 5-FU, leucovorin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Kinesio Taping on Balance and Functional Performance in Stroke Patients
Status: UNKNOWN
Conditions: Stroke, Acute|Hemiplegia|Balance|Functional Performance
Interventions: OTHER: Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies
Status: RECRUITING
Conditions: Kaposiform Hemangioendothelioma|Tufted Angioma|Superficial Vascular Anomalies|Superficial Lymphatic Malformations
Interventions: DRUG: Percutaneous sirolimus|DRUG: Oral sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Night Administration of Low Dose Aspirin in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: ASA evening|DRUG: Acetylsalicylic morning|DRUG: Placebos morning|DRUG: Placebo evening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TachoSil® Versus Surgicel® Original for the Secondary Treatment of Local Bleeding in Adult and Pediatric Patients Undergoing Hepatic Resection Surgery
Status: COMPLETED
Conditions: Hemorrhage
Interventions: BIOLOGICAL: TachoSil®|DEVICE: Surgicel® Original
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Nursing Education on Oral Mucositis in Bone Marrow Transplant Patients
Status: COMPLETED
Conditions: Blood Stem Cell Transplant Failure|Oral Mucositis|Nurse's Role
Interventions: OTHER: Oral mukositis nurse's education for patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Comparison of Zidovudine (AZT) Used Alone or in Combination With Didanosine (ddI) or Dideoxycytidine (ddC) in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Zalcitabine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Trans Sodium Crocetinate (TSC) in SARS-CoV-2 (COVID-19) Infected Subjects
Status: COMPLETED
Conditions: SARS-CoV-2 (Covid19)
Interventions: DRUG: Trans Sodium Crocetinate|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Omega 3 Fatty Acid Trial
Status: COMPLETED
Conditions: Omega-3 Fatty Acids|Pediatric Bipolar Disorder|Adolescent Bipolar Disorder|Magnetic Resonance Spectroscopy Imaging
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp.
Status: TERMINATED
Conditions: Bloodstream Infections
Interventions: DRUG: Meropenem|DRUG: Piperacillin-tazobactam combination product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Pain After Using Reciprocating Motion With Reciproc Files Versus Adaptive Motion With Twisted File Adaptive
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DEVICE: Twisted file adaptive|DEVICE: Reciproc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: N-acetyl Cysteine for the Prevention of Oral Mucositis After Autologous Hematopoietic Cell Transplantation.
Status: UNKNOWN
Conditions: Mucositis|Transplant-Related Disorder
Interventions: DRUG: N acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Midazolam Efficacy for Sedating Preschoolers Undergoing Dental Treatment
Status: COMPLETED
Conditions: Early Childhood Caries
Interventions: DRUG: Midazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics for the Prophylaxis of Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: DIETARY_SUPPLEMENT: Probiotic 1|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Probiotic 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: the Effect of Preoperative Sodium Ibuprofen on Postoperative Endodontic Pain
Status: COMPLETED
Conditions: Irreversible Pulpitis
Interventions: DRUG: nurofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Ramosetron Pre-treatment for PONV and QT Prolongation
Status: COMPLETED
Conditions: PONV|Prolonged QTc Interval
Interventions: DRUG: Ramosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study in Postmenopausal Women to Determine the Lowest Effective Dose for Relief of Moderate to Severe Hot-Flushes
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: Climara PRO (Estradiol / Levonorgestrel transdermal)|DRUG: Menostar (Estradiol transdermal)|DRUG: Placebo transdermal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease|Dry Eye Syndrome
Interventions: DRUG: SJP-0132|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intraoperative Brain Microdialysis to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection.
Status: ENROLLING_BY_INVITATION
Conditions: Epilepsy
Interventions: PROCEDURE: Intraoperative brain microdialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of rAAV-hRS1 in Patients With X-linked Retinoschisis (XLRS)
Status: COMPLETED
Conditions: X-linked Retinoschisis
Interventions: BIOLOGICAL: rAAV2tYF-CB-hRS1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The FAVOR V AMI Trial
Status: NOT_YET_RECRUITING
Conditions: ST-Segment Elevation Myocardial Infarction|Multivessel Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DIAGNOSTIC_TEST: FAST Technique|DIAGNOSTIC_TEST: Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequential FDG-PET (Positron Emission Tomography) and Induction Chemotherapy in Locally Advanced Adenocarcinoma of the Esophagogastric Junction (AEG)
Status: TERMINATED
Conditions: Adenocarcinomas of the Esophagogastric Junction
Interventions: RADIATION: neoadjuvant radiochemotherapy in metabolic non responders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N-acetylcysteine to Prevent Renal Failure
Status: UNKNOWN
Conditions: Kidney Failure, Acute|Oxidative Stress Induction
Interventions: DRUG: N-acetylcysteine|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Organ Perfusion With Custodiol-N Solution Compared With Custodiol Solution in Heart Transplantation
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Custodiol-N|DRUG: Custodiol|PROCEDURE: organ perfusion for heart transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: "Safety in Dementia": An Online Caregiver Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Caregivers|Decision Making|Alzheimer Disease|Social Media|Safety|Suicide
Interventions: BEHAVIORAL: Safety in Dementia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Prednisone In the Treatment of Ocular Myasthenia
Status: TERMINATED
Conditions: Ocular Myasthenia Gravis
Interventions: DRUG: Prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacral Nerve Stimulation for Faecal Incontinence - Placebo or Clinical Effective
Status: COMPLETED
Conditions: Faecal Incontinence|Fecal Incontinence
Interventions: DEVICE: Sacral nerve stimulation at different stimulation amplitudes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Early-Episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: BEHAVIORAL: Emotional Engagement Distress Tolerance Intervention|BEHAVIORAL: Health Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Quality of Life Study of Peginterferon-Alfa-2a Plus Ribavirin in Participants With Chronic Hepatitis C and Persistently Normal Alanine Transaminase (ALT) Levels
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
Status: RECRUITING
Conditions: Fibromyalgia|Chronic Fatigue Syndrome|Multiple Sclerosis|Healthy
Interventions: DRUG: DPA-714 PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hernia-Prophylaxis in Acute Care Surgery H-PACS
Status: COMPLETED
Conditions: Incisional Hernia
Interventions: PROCEDURE: Strattice|PROCEDURE: Single running suture of abdominal fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies
Status: RECRUITING
Conditions: Pediatric Hematologic Malignancies
Interventions: DEVICE: Ex Vivo T-cell receptor alpha-beta and CD19+ Depletion using CliniMACs Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Bone Calcium Content in Children With Kidney Disease Treated With Two Different Medicines
Status: UNKNOWN
Conditions: Chronic Kidney Diseases
Interventions: OTHER: calcium carbonate|OTHER: sevelamer carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Recovery in Advanced , ARV-naïve, HIV-1-infected Individuals Taking Dolutegravir or Ritonavir-boosted Darunavir
Status: UNKNOWN
Conditions: Acquired Immune Deficiency Syndrome Virus
Interventions: DRUG: Dolutegravir|DRUG: Darunavir/r
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab (Avastin) Versus Placebo in Combination With Capecitabine (Xeloda) and Cisplatin as First-Line Therapy for Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Bevacizumab|DRUG: Placebo|DRUG: Capecitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modified Downregulation for Women With Adenomyosis of the Uterus Prior to Frozen-thawed Embryo Transfer.
Status: UNKNOWN
Conditions: Adenomyosis
Interventions: DRUG: GnRH analogue downregulation|OTHER: Participant questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention
Status: COMPLETED
Conditions: Intervention|Transradial
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bevacizumab Versus Combined Bevacizumab and Triamcinolone for Refractory Diabetic Macular Edema; a Randomized Clinical Trial
Status: UNKNOWN
Conditions: Diabetic Macular Edema
Interventions: DRUG: Triamcinolone, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Doxil, Gemcitabine, and Velcade (PS341) in Advanced Cancer Patients
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Doxil|DRUG: Gemcitabine|DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Knee Pain
Status: COMPLETED
Conditions: The Aim of This Research is to Investigate the Effect of Prolotherapy on Quality of Life and Painkiller Use in Patients With Chronic Knee Pain
Interventions: PROCEDURE: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Propofol and Fentanyl for Prevention of Emergence Agitation in Children After Sevoflurane Anesthesia
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: Administration of propofol|DRUG: Administration of fentanyl|DRUG: Administration of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
Status: COMPLETED
Conditions: Pre Diabetes|Polycystic Ovary Syndrome|Obesity Android
Interventions: DRUG: Liraglutide Pen Injector [Saxenda]|DRUG: Placebo Liraglutide Pen Injector
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention and Early Detection of Ulcer Recurrence in Patients With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Recurrence|Diabetic Foot|Thermography|Quality of Life
Interventions: DEVICE: Prevention Strategies|DEVICE: Standard Strategiies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Dexamethasone and Morphine as an Adjuvant to Bupivacaine for Post-operative Analgesia
Status: COMPLETED
Conditions: Lower Extremities Fracture
Interventions: DRUG: Dexamethasone 8 mg|DRUG: Morphine 2 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effectiveness of a Multifaceted Knowledge Translation Intervention on Pain in Hospitalized Infants
Status: COMPLETED
Conditions: Pain|Infant
Interventions: BEHAVIORAL: ImPaC Resource Intervention (INT)|OTHER: Standard Practice (SP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|HIV Infection|Metastatic Malignant Solid Neoplasm|Recurrent Malignant Solid Neoplasm|Unresectable Solid Neoplasm
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Use of Naldebain® ER Injection and Precedex® After VATS
Status: NOT_YET_RECRUITING
Conditions: Acute Post Operative Pain|Chronic Post Operative Pain|Postoperative Complications
Interventions: DRUG: PRECEDEX INJ★ 2ML|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib and Vinorelbine in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: lapatinib ditosylate|DRUG: vinorelbine ditartrate|GENETIC: comparative genomic hybridization|GENETIC: cytogenetic analysis|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymerase chain reaction|GENETIC: polymorphism analysis|GENETIC: proteomic profiling|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|DRUG: lapatinib ditosylate|DRUG: Vinorelbine ditartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double Blind Comparison of Atosiban in Patients With RIF Undergoing IVF Treatment
Status: UNKNOWN
Conditions: Repeated Implantation Failure
Interventions: DRUG: atosiban|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Tolerability and Efficacy of Lytixar™ (LTX-109) on Uncomplicated, Gram-positive, Skin Infection
Status: COMPLETED
Conditions: Gram-positive, Skin Infections|Mild Eczema/Dermatoses|Atopic Dermatitis
Interventions: DRUG: LTX-109
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Veteran Peer Coaches Optimizing and Advancing Cardiac Health
Status: COMPLETED
Conditions: Cardiovascular Disease (CVD)|Hypertension|Hyperlipemia|Obesity
Interventions: OTHER: Community-based peer health coach intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Proof of Concept Trial to Confirm That the Recovery of Patients Treated in the Intensive Care Unit Requiring Mechanical Ventilation is Beneficially Affected by the Environmental Simulation of Daytime and Night Time Alternation as Well as by the Nutrition Protocol Corresponding to the Daily Rhythm
Status: UNKNOWN
Conditions: Critical Illness|Mechanical Ventilation
Interventions: OTHER: Controlled light and noise|OTHER: Controlled nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transbronchial Lung Biopsy Guided by ENB
Status: COMPLETED
Conditions: Lung Lesion(s) Requiring Evaluation
Interventions: DEVICE: ENB-TBLB|DEVICE: X-ray-TBLB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Virtual Reality and Video Games in Cardiac Rehabilitation Programs
Status: UNKNOWN
Conditions: Adherence, Patient|Physical Disability|Cardiovascular Diseases|Treatment Adherence|Satisfaction
Interventions: OTHER: Cardiac rehabilitation program|OTHER: Experimental intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Anti-IL-6R mAb Injection in Patients With iMCD
Status: RECRUITING
Conditions: Idiopathic Multicentric Castleman's Disease
Interventions: BIOLOGICAL: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 4mg/kg|BIOLOGICAL: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 6mg/kg|BIOLOGICAL: Recombinant Humanized Anti-interleukin-6 Receptor Monoclonal Antibody Injection 8mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Engensis (VM202) in the Treatment of Chronic Non-Healing Foot Ulcers
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic
Interventions: GENETIC: Engensis (VM202)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Direct or Subacute Coronary Angiography in Patients With Out of Hospital Cardiac Arrest Without Coma.
Status: RECRUITING
Conditions: Cardiac Arrest, Out-Of-Hospital|Angiography|Percutaneous Coronary Intervention|Coma
Interventions: PROCEDURE: Acute CAG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol and Micro T-Wave Alternans in Hypertensives With Chronic Kidney Disease
Status: TERMINATED
Conditions: Vascular Disease|Kidney Disease
Interventions: OTHER: Carvedilol and Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Transcatheter Aortic Valve Replacement (TAVR)-Pilot Trial
Status: WITHDRAWN
Conditions: Transcatheter Aortic Valve Replacement (TAVR)
Interventions: PROCEDURE: Prehabilitation visit/increased physical therapy post-TAVR|PROCEDURE: Standard of Care Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of the Safety and Efficacy of a Tofimilast in Adult Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: tofimilast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Tunatar da ni. The Immunization Reminder and Information SMS System (IRISS)
Status: COMPLETED
Conditions: Low Immunization Uptake
Interventions: OTHER: Community engagement|OTHER: IRISS advert for opt-in|OTHER: One-time SMS broadcast on immunization|OTHER: Scheduled weekly SMS reminder of health facility RI schedule to community leaders|OTHER: Scheduled bi weekly RI messages to community leaders|OTHER: Responsive individualized child vaccination schedule reminder to caregivers who opt-in|OTHER: Responsive one-time SMS message on hand washing to those that erroneously register on IRISS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pre-pectoral AlloDerm® to Reinforce Tissues in Tissue Expander Breast Reconstruction
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Quality of Life|Breast Cancer|Breast Prosthesis; Pain
Interventions: PROCEDURE: Pre-pectoral Tissue Expander
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Male-specific Psychotherapeutic Program for Major Depressive Disorders
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Male-specific psychotherapeutic program (MSPP)|BEHAVIORAL: Cognitive beahvioral therapy (CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability and Efficacy of Two Injections of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Placebo|DRUG: SM04690
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Administration of Autologous Dendritic Cells (DCs) Infected With an Adenovirus Expressing Her-2
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: BIOLOGICAL: CD34+ derived DCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Single-blind Comparison Between Standard and Individualized Approach in Bowel Preparation Before Colonoscopy
Status: COMPLETED
Conditions: Bowel Cleansing Process|Colonoscopy
Interventions: DRUG: Standard approach|DRUG: Individualized approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Malignancies|Solid Tumor|Hematological Malignancy
Interventions: DRUG: Pelabresib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Estrogen Therapy on Objective Sleep Quality in Postmenopausal Women
Status: COMPLETED
Conditions: Insomniac Postmenopausal Women
Interventions: DRUG: Estrogen patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine to Prevent Recurrence of Hepatocellular Carcinoma After Curative Resection
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Neoplasm Metastasis
Interventions: DRUG: Capecitabine|OTHER: No other preventive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Group Psychological Intervention for People With Emotional Disorders
Status: UNKNOWN
Conditions: To Assess the Clinical Usefulness and Acceptability Level of the UP Online Group Format in Argentina as Well as Participants' Satisfaction
Interventions: BEHAVIORAL: Unified Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts
Status: COMPLETED
Conditions: Condylomata Acuminata|Papillomavirus Infections|Skin Diseases, Viral|Skin Diseases, Infectious|Skin Diseases|Sexually Transmitted Diseases, Viral|Sexually Transmitted Diseases|Warts
Interventions: COMBINATION_PRODUCT: VP-102 and applicator|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes to Function and Quality of Life and Patient Experience for Patients Undergoing Treatments for Recurrent Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Oropharynx Carcinoma
Interventions: OTHER: Treatment for recurrent oropharyngeal cancer (curative/ palliative)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment With Infliximab in a Medical Setting (Study P05587)
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Infliximab 5 mg/kg|BIOLOGICAL: Infliximab 5 mg/kg every 6 weeks|BIOLOGICAL: Infliximab 7 mg/kg every 8 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Abnormalities Detected by MRI, Realized at the Age of Term and the Emergence of Executive Functions
Status: UNKNOWN
Conditions: Premature Baby 25 to 32 Weeks
Interventions: PROCEDURE: term MRI, executive EF functions testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Intravenous BCX-1777 in Relapsed or Refractory Aggressive T-Cell Leukemias or Lymphomas
Status: COMPLETED
Conditions: Leukemia, Lymphocytic|Lymphoma
Interventions: DRUG: BCX-1777
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 68Ga-FAPI-46 and 18F-FDG PET/CT Imaging for Detecting Recurrent Tumor Lesions in Patients of Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI-46|DIAGNOSTIC_TEST: 18F-FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Auriculotherapy - Pain Management of Aspiration Abortion
Status: COMPLETED
Conditions: Abortion in First Trimester
Interventions: DEVICE: Acupressure with Beads|DEVICE: Acupuncture with Needles|DEVICE: Placebo Adhesive Disks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cryoballoon vs. Irrigated Radiofrequency Catheter Ablation: Double Short vs. Standard Exposure Duration
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary Vein Isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stratified Therapy on Pediatric AAGN
Status: RECRUITING
Conditions: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|ANCA-Associated Glomerulonephritis
Interventions: DRUG: GlucoCorticoid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for Combined Analysis of CTC and Exosomes on Predicting the Efficacy of Immunotherapy in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: CTC PD-L1, exosomal PD-L1, and exosomal LAG-3 detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy|Spastic|Malnutrition
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: NSS Nutritional Support System|DRUG: Deworming|OTHER: Specific diet|OTHER: Conventional diet (WHO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Miami Membrane for Potency (MMEP) Trial
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Amniotic Membrane Placement|BEHAVIORAL: EPIC 26|OTHER: PSA Measurement|BEHAVIORAL: Sexual History Inventory for Men
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Cancer|Clear Cell Carcinoma
Interventions: DRUG: Rucaparib|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Tolerability and Safety Study in Rheumatoid Arthritis (0812-008)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: MK0812 / Duration of Treatment: 12 Weeks|DRUG: Comparator: placebo (unspecified) / Duration of Treatment: 12 Weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Glutamatergic Modulation on Cocaine Self-administration
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: CI-581a|DRUG: CI-581b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Immuno-OCT
Status: NOT_YET_RECRUITING
Conditions: Colon Carcinoma|Barrett Esophagus|Gastrointestinal Dysplasia
Interventions: DRUG: Bevacizumab-800CW
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Quality of Life of Patients With Metastatic Non-small Cell Lung Cancer With Supplementary Therapy With IGEN-0206
Status: COMPLETED
Conditions: Quality of Life of Patients|Non-small Cell Lung Cancer Metastatic
Interventions: DIETARY_SUPPLEMENT: IGEN0206|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Analytic Tools for aHUS and C3G Diagnosis
Status: RECRUITING
Conditions: Hemolytic-Uremic Syndrome|Membranoproliferative Glomerulonephritis|Healthy
Interventions: DIAGNOSTIC_TEST: C3NEF assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness
Status: ENROLLING_BY_INVITATION
Conditions: Stroke|Neurologic Disorder|Traumatic Brain Injury|Acquired Brain Injury
Interventions: OTHER: Table Top Visual Intervention|DEVICE: Bioness Integrated Therapy System Visual Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ojeok-san on Korean Patients With Cold Hypersensitivity in the Hands and Feet
Status: COMPLETED
Conditions: Cold Hypersensitivity
Interventions: DRUG: Ojeok-San|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Smoked Cannabis for Improving Quality of Life in Advanced Cancer Patients
Status: TERMINATED
Conditions: Cancer|Chronic Pain Due to Malignancy (Finding)
Interventions: COMBINATION_PRODUCT: PPP001|COMBINATION_PRODUCT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: RT plus Nimotuzumab|DRUG: RT plus Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Issues in Insulin Pump Therapy in Children With Type 1 Diabetes Mellitus (DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Insulin-Dependent
Interventions: DEVICE: Continuous subcutaneous insulin infusion therapy|DEVICE: Multiple daily injection therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Respiratory Training on Exercise Tolerance in COPD
Status: UNKNOWN
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Normocapnic hyperpnoea intervention|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Physical Fitness in Young Healthy Adults After COVID-19 Infection
Status: COMPLETED
Conditions: COVID-19
Interventions: OTHER: Physical Activity Level|OTHER: Evaluation of knee extension and elbow flexion muscle strength|OTHER: Evaluation of functional strength of trunk muscles|OTHER: Muscle Endurance|OTHER: Flexibility|OTHER: Balance|OTHER: Fatigue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CT Myocardial Perfusion to Guide the Diagnosis and Treatment of Patients With Stable Coronary Artery Disease (POTENTIAL)
Status: RECRUITING
Conditions: Treatment Decision, Coronary Artery Disease
Interventions: PROCEDURE: Invasive coronary angiography|OTHER: routine medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT