pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pre-marketing Clinical Trial to Evaluate the Safety and Efficacy of the Filler of Hyaluronic Acid Recombinant Collagen
Status: NOT_YET_RECRUITING
Conditions: Wrinkle|Scar|Laxity; Skin
Interventions: DEVICE: Karisma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GB201 in Combination With Weekly Paclitaxel and Low-dose Gemcitabine in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Cancer
Interventions: DRUG: GB201|DRUG: Paclitaxel|DRUG: Gemcitabine|OTHER: Standard of care treatment options
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DKM420 in Patients With Osteoarthritis of Knee
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: DEVICE: DKM420|DEVICE: Conjuran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Large Multi-site Study on Self-administered Mindfulness
Status: COMPLETED
Conditions: Body Scan Meditation|Loving-Kindness Meditation|Mindful Breathing Meditation|Mindful Walking Meditation|Control Condition
Interventions: BEHAVIORAL: Body-scan meditation|BEHAVIORAL: Mindful Breathing meditation|BEHAVIORAL: Loving Kindness meditation|BEHAVIORAL: Mindful Walking|BEHAVIORAL: Listening of a story
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Soy Protein on Neuropathic Pain
Status: TERMINATED
Conditions: Neuralgia
Interventions: DIETARY_SUPPLEMENT: Whole soybean soymilk powder|DIETARY_SUPPLEMENT: Whole milk powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The ESTxENDS Trial- Substudy on the Effect on Toxins From Using Electronic Nicotine Delivery Systems (ENDS/Vaporizer/E-cig)
Status: COMPLETED
Conditions: Smoking Cessation|Toxicity
Interventions: OTHER: ENDS (Vaporizer/e-cig) and smoking cessation counseling|OTHER: Smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase III Study to Assess the Lot-to-lot Consistency of GSK's Investigational RSV Maternal Vaccine and the Immune Response and Safety of RSV Maternal Vaccine When Given Alone or Co-administered With GSK's Influenza D-QIV Vaccine in Healthy Non-pregnant Women.
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: COMBINATION_PRODUCT: RSVPreF3(120 μg)|COMBINATION_PRODUCT: Flu Quadrivalent influenza vaccine (15 μg HA)|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: International, Multicenter, Study of One-year, Open-label, Titrated Oral Tolvaptan Tablet Administration in Patients With Chronic Hyponatremia
Status: COMPLETED
Conditions: Hyponatremia
Interventions: DRUG: Tolvaptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sensory Integration Balance Training on Children With ABI
Status: ACTIVE_NOT_RECRUITING
Conditions: Children With Acquired Brain Injury
Interventions: OTHER: Sensory integration therapy for balance and gait training|OTHER: Traditional Physiotherapy for balance and gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Antiviral Treatment in Combination With Low-dose Gemcitabine in EBV-associated Gastric Cancer (EBVaGC)
Status: WITHDRAWN
Conditions: Gastric Cancer
Interventions: DRUG: Antiviral treatment in combination with low-dose gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-Drug Interaction Study of CTL0801 and CTL0802 Compared to Coadministration in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Health, Subjective
Interventions: DRUG: CTL0801 (Azilsartan)|DRUG: CTL0802 (Rosuvastatin)|DRUG: CTL0801 (Azilsartan) + CTL0802 (Rosuvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing a Nurse-Driven Aromatherapy Protocol to Decrease the Effect of Postoperative Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting (PONV)
Interventions: OTHER: Lavender Essential Oil|OTHER: Ginger Essential Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Basal Insulin in the Management of Patients With Diabetic Ketoacidosis (DKA)
Status: COMPLETED
Conditions: Diabetic Ketoacidosis
Interventions: DRUG: insulin glargine+ glulisine|DRUG: NPH + Regular insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chart Review: Drug Utilization Study in Participants Who Received Ozurdex™ (Dexamethasone Intravitreal Implant) 0.7 mg Injections for Visual Impairment Due to Diabetic Macular Edema (DME)
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Dexamethasone intravitreal implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Saphenous Nerve Block for Foot and Ankle Surgery
Status: COMPLETED
Conditions: Saphenous Nerve Block
Interventions: DEVICE: Ultrasound Guidance|DEVICE: Ultrasound guidance + nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castrate-Resistant Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: SV-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mirtazapine for Treating Cocaine Dependent Individuals Who Also Suffer From Depression
Status: COMPLETED
Conditions: Cocaine Dependence|Depression
Interventions: DRUG: Mirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae
Status: UNKNOWN
Conditions: Antibiotic Resistant Infection
Interventions: DRUG: Fosfomycin|DRUG: Tigecycline|DRUG: Polymyxin B
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Giredestrant Plus Palbociclib Compared With Anastrozole Plus Palbociclib for Postmenopausal Women With Estrogen Receptor-Positive and HER2-Negative Untreated Early Breast Cancer (coopERA Breast Cancer)
Status: COMPLETED
Conditions: Early Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Anastrozole|DRUG: Palbociclib|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: IPMN|IPMN, Pancreatic
Interventions: DRUG: Sulindac 400 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety in a Randomised Acute Pain Study of MR308: STARDOM2.
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: MR308|DRUG: MR308|DRUG: MR308|DRUG: MR308
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Training and Follow-up Given to Cancer Patients Receiving Chemotherapy According to the Neuman Systems Model on the Development of Oral Mucositis and Perceptions of Comfort in Patients
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Training and Follow-up According to the Neuman Systems Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Controlled nutritional intervention based on the Mediterranean diet|OTHER: Controlled nutritional intervention based on the Mediterranean diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Safety and Efficacy of C-CHOP in Untreated Subjects With Angioimmunoblastic T Cell Lymphoma
Status: UNKNOWN
Conditions: Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Chidamide|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Efficacy of Leg Cycling as Part of Physiotherapy Treatment in Elderly Patients With Hip Fracture
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: OTHER: Physiotherapy treatment & leg cycling|OTHER: Physiotherapy treatment & music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reading Stories to Premature Babies Reinforces Mother-baby Synchronies?
Status: RECRUITING
Conditions: Premature Infant|Mother-Baby Synchrony
Interventions: OTHER: Physiologically evaluate the impact of reading history on the mother-baby synchronies in a context of premature birth requiring hospitalization in neonatal medicine.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Feasibility and Effectiveness of Virtual Reality & Use of Body Weight Support Treadmill Training in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Virtual Reality|BEHAVIORAL: Conventional Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
Status: COMPLETED
Conditions: Back Pain|Fusion of Spine, Lumbar Region|Spinal Stenosis
Interventions: OTHER: Optimizing basal infusion (B.I)|OTHER: Conventional PCA mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effect of Vitamin K3-lotion for the Treatment of Cetuximab Induced Folliculitis
Status: COMPLETED
Conditions: Folliculitis
Interventions: OTHER: Vitamin K3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Person-centred Prescription Model at the End of Life
Status: COMPLETED
Conditions: End-Of-Life|Inappropriate Prescribing|Deprescriptions|Palliative Medicine|Geriatrics
Interventions: OTHER: Person-Centred Prescription Model
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Sunscreens in Patients With Cutaneous Lupus Erythematosus(CLE)
Status: COMPLETED
Conditions: Cutaneous Lupus Erythematosus
Interventions: OTHER: UV A and B irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fit & Active Seniors Trial
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Dance Group|BEHAVIORAL: Strength, Stretching, Stability|BEHAVIORAL: Walking|BEHAVIORAL: Walking + Nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation of ETCO2 to PaCO2 Measured by Sentri Nasal Cannula
Status: UNKNOWN
Conditions: Ventilatory Depression
Interventions: DEVICE: SentriTM ETCO2 adult nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Roflumilast Versus Methotrexate in Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Roflumilast|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Obesity-related Molecular Typing and Traditional Chinese Medicine Constitution
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Obesity
Interventions: DIAGNOSTIC_TEST: blood test|DIAGNOSTIC_TEST: genetic test|DIAGNOSTIC_TEST: Constitution in Chinese Medicine Questionnaire|DIAGNOSTIC_TEST: Epworth Sleepiness Scale|DIAGNOSTIC_TEST: cephalometry|DIAGNOSTIC_TEST: polysomnography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Extra Corporeal Membrane Oxygenation in the Acute Respiratory Distress Syndrome: Utility of a Biomarker to Assess the Membrane Efficiency in Improving Oxygenation
Status: COMPLETED
Conditions: Extra Corporel Membrane Oxygenation and Mciroparticles
Interventions: OTHER: Blood draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lenalidomide and Docetaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: docetaxel|DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coordinated Access to Care From Hospital Emergency Departments
Status: COMPLETED
Conditions: Mental Health
Interventions: OTHER: Co-ordinated Access to Care from Hospital Emergency Departments|OTHER: Coordinated Access to Care from Hospital Emergency Departments|BEHAVIORAL: Counseling and Resource Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prebiotics Change Microflora and Decrease LPS
Status: COMPLETED
Conditions: Prebiotics Effect
Interventions: OTHER: XOS|OTHER: INU-XOS|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: AnovaOS Network Powered Patient Registry
Status: RECRUITING
Conditions: Infectious Disease|Neoplasms|Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89)|Endocrine, Nutritional and Metabolic Diseases (E00-E89)|Mental and Behavioural Disorders|Diseases of the Nervous System|Diseases of the Eye and Adnexa|Diseases of the Ear and Mastoid Process|Diseases of the Circulatory System|Diseases of the Respiratory System|Diseases of the Digestive System|Diseases of the Skin and Subcutaneous Tissue|Diseases of the Musculoskeletal System and Connective Tissue|Diseases of the Genitourinary System|Pregnancy, Childbirth and the Puerperium|Certain Conditions Originating in the Perinatal Period|Congenital Malformations, Deformations and Chromosomal Abnormalities (Q00-Q99)|Symptoms, Signs and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified|Injury, Poisoning and Certain Other Consequences of External Causes|External Causes of Morbidity and Mortality|Factors Influencing Health Status and Contact With Health Services
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: exogenous surfactant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Collaborative Care Coordination Program for Alzheimer's Disease and Related Dementias
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease and Related Dementias (ADRD)
Interventions: BEHAVIORAL: Dementia Care Consultation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Intervention to Improve Implantable Cardioverter-Defibrillator Deactivation Conversations
Status: COMPLETED
Conditions: Communication|Heart Failure
Interventions: BEHAVIORAL: Communication training for cardiologists.|OTHER: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)
Status: RECRUITING
Conditions: CIN 2/3|HPV Infection|Pre-Cancerous Dysplasia|Cervical Dysplasia|HPV Related Disease
Interventions: DRUG: Artesunate vaginal insert|DRUG: Placebo vaginal insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravital Microscopy in Human Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor, Adult|Clinical Stage IV Gastric Cancer AJCC v8|Gastric Carcinoma|Malignant Solid Neoplasm|Metastatic Colorectal Carcinoma|Metastatic Gastric Carcinoma|Metastatic Primary Malignant Brain Neoplasm|Metastatic Sarcoma|Postneoadjuvant Therapy Stage IV Gastric Cancer AJCC v8|Resectable Colorectal Carcinoma|Resectable Liver and Intrahepatic Bile Duct Carcinoma|Resectable Pancreatic Carcinoma|Resectable Sarcoma|Stage IV Colorectal Cancer AJCC v8
Interventions: DEVICE: Diagnostic Microscopy|DRUG: Fluorescein Sodium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mindful Positive Reappraisal: a Daily Diary Randomized Controlled Trial
Status: COMPLETED
Conditions: Mental Health Wellness 1
Interventions: BEHAVIORAL: Self-Administered Mindful-Reappraisal Exercise|BEHAVIORAL: Self-Administered Reappraisal-Only Exercise|BEHAVIORAL: Self-Administered Event Recall Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Equity in Prevention and Progression of Hypertension by Addressing Barriers to Nutrition and Physical activitY
Status: RECRUITING
Conditions: Prehypertension|Hypertension|Blood Pressure
Interventions: BEHAVIORAL: Health Education|BEHAVIORAL: Individual-Level Peer Support|BEHAVIORAL: Community-Level Peer Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulsed Shortwave Therapy Adjunct Pain and Recovery in Total Knee Replacement
Status: UNKNOWN
Conditions: Total Knee Arthroplasty
Interventions: DEVICE: pulsed shortwave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Advancing Adolescent Screening and Brief Intervention Protocols in Primary Care Settings
Status: WITHDRAWN
Conditions: Substance Abuse
Interventions: BEHAVIORAL: computer-assisted Screening & Brief Advice|BEHAVIORAL: computer-assisted Screening & Brief Advice Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamotrigine for the Treatment of Mania in Youth Ages 6-17 With Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mania
Interventions: DRUG: lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients
Status: COMPLETED
Conditions: Malaria in Pregnant HIV + Patients
Interventions: DRUG: Mefloquine|DRUG: Sulphadoxine-Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Acute Effects of Exercise at Different Temperatures in Allergic Rhinitis Patient
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: Cycling exercise in room temperature at 25 degree Celsius.|OTHER: Cycling exercise in room temperature at 34 degree Celsius.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Very Long Versus Overlapping Stents in Long Coronary Lesions
Status: WITHDRAWN
Conditions: Coronary Artery Disease|Chronic Coronary Syndrome|Drug Eluting Stents
Interventions: DEVICE: Percutaneous Coronary Intervention and Stent Implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: L-PRF Versus Connective Tissue Graft Associated to Coronally Advanced Flap in Gingival Recession Treatment
Status: COMPLETED
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: Leukocyte and Platelet Rich Fibrin plus Coronally Advanced Flap|PROCEDURE: Connective tissue graft plus Coronally Advanced Flap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Venetoclax, Lenalidomide and Rituximab in Patients With Relapsed/Refractory Mantle Cell Lymphoma
Status: UNKNOWN
Conditions: Relapsed Non Hodgkin Lymphoma
Interventions: DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of SVV-guided Fluid Therapy on Outcomes After Major Abdominal Surgery
Status: COMPLETED
Conditions: Goal-directed Fluid Therapy
Interventions: DEVICE: the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Marketing Surveillance To Observe Safety And Efficacy Of Xyntha Solofuse Prefilled Syringe
Status: COMPLETED
Conditions: Factor VIII Deficiency, Congenital|Factor 8 Deficiency, Congenital|Autosomal Hemophilia A|Classic Hemophilia|Hemophilia A, Congenital
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Afimoxifene in Treating Patients With Breast Cancer Who Have Undergone Radiation Therapy on One Breast
Status: RECRUITING
Conditions: Cancer Survivor|Ductal Breast Carcinoma In Situ|Invasive Breast Carcinoma
Interventions: DRUG: Afimoxifene|PROCEDURE: Core Biopsy|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Extended CTA for the Successful Screening of Cardioaortic Thrombus in Acute Ischemic Stroke and TIA (DAYLIGHT) Trial
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Transient Ischemic Attack|Intracardiac Thrombus
Interventions: DIAGNOSTIC_TEST: extended CTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open Label, Single Dose, Non-randomized Study to Assess the Drug to Drug Interaction of Briakinumab on CYP Substrates.
Status: WITHDRAWN
Conditions: Moderate to Severe Plaque Psoriasis
Interventions: DRUG: briakinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Chewing Clopidogrel in Addition to Regular Oral Clopidogrel Treatment to Improve Platelets Aggregation in Patient With NON ST ELEVATION MI
Status: UNKNOWN
Conditions: Platlet Aggregation|Major Bleeding Outcomes
Interventions: DRUG: clopidogrel by chewing|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study Evaluating ONO-4053 and Cetirizine in Subjects With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Cetirizine|DRUG: High dose ONO-4053|DRUG: Low dose ONO-4053|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Probiotic Yeast on the Composition of the Vaginal Microbiota in Healthy Women
Status: COMPLETED
Conditions: Vaginal Health
Interventions: DIETARY_SUPPLEMENT: Saccharomyces cerevisiae, dose 500|DIETARY_SUPPLEMENT: Saccharomyces cerevisiae, dose 1000|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pivotal Clinical Investigation Confirming the Safety and Accuracy of the Glyconics-DS in Assessment of Glycated Nail Keratin in Individuals With Unknown Diabetes Status and Performance Evaluation of the Glyconics SW Package
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre-diabetes|Undiagnosed Diseases
Interventions: DEVICE: Near-infrared (NIR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Development of Electroencephalography (EEG) and Magnetoencephalography (MEG) Source Reconstruction With Fast Multipole Method
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Finger tapping|OTHER: Median nerve stimulation|OTHER: Speech processing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
Status: COMPLETED
Conditions: Metastasis|Breast Cancer
Interventions: DRUG: NKTR-102|DRUG: Eribulin|DRUG: Ixabepilone|DRUG: Vinorelbine|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Sampling Site When Assessing Glucose Tolerance or Insulin Sensitivity With Oral Glucose Ingestion
Status: COMPLETED
Conditions: Hyperglycemia|Insulin Sensitivity
Interventions: BEHAVIORAL: Rest|BEHAVIORAL: Exercise|OTHER: Dorsal Hand Vein Cannulation (heated hand technique)|OTHER: Venous Cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Human Menstrual Blood Cells to Treat Acute Lung Injury Caused by H7N9 Bird Flu Virus Infection
Status: UNKNOWN
Conditions: Acute Lung Injury|Acute Respiratory Distress Syndrome (ARDS)|Multiple Organ Failure
Interventions: DRUG: Menstrual blood stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Of Local Anesthetic Agents And Steroid On Tracheal Tube Cuff
Status: COMPLETED
Conditions: Anesthesia Intubation Complication|Intubation Complication|Sore Throat
Interventions: DRUG: Lidocaine 10% Spray|DRUG: Mometasone nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery
Status: COMPLETED
Conditions: Knee Injuries and Disorders|Hip Injuries and Disorders|Opiate Addiction
Interventions: BEHAVIORAL: Video Education|BEHAVIORAL: Usual Care Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Methylene Blue - Mediated Photodynamic Therapy for Diabetic Lower Limb Ulcer
Status: UNKNOWN
Conditions: Diabetic Extremity Lower Ulcers
Interventions: COMBINATION_PRODUCT: methylene blue|COMBINATION_PRODUCT: Photon therapy instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromegaly|GEP-NET
Interventions: DRUG: Debio 4126|DRUG: Sandostatin LAR|DRUG: Somatuline ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: MDMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Solid Tumors|HER2-positive Breast Cancer|HER2-positive Colorectal Cancer|HER2-positive Gastroesophageal Cancer|HER2-positive Endometrial Cancer
Interventions: DRUG: BDC-1001|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers
Status: COMPLETED
Conditions: Myocardial Infarction|Inflammation|Acute Coronary Syndrome (ACS)|Reperfusion Injury
Interventions: BIOLOGICAL: Salmonella typhi vaccine (Typhim Vi®)|DRUG: Oxygen (Oxymask®)|DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Optimized Savory Cluster on Glycemic and Insulinemic Responses in Healthy Individuals
Status: COMPLETED
Conditions: Peak Rise of Blood Glucose
Interventions: OTHER: Test Cluster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Open-Label Investigation of the Adjuvant Therapeutic Effects of Galantamine in Patients With Chronic Schizophrenia and Persistent Deficit Symptoms
Status: COMPLETED
Conditions: Chronic Schizophrenia
Interventions: DRUG: Galantamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Urinary Tract Symptoms|Female Genitourinary Disease|Urinary Stress Incontinence|Urinary Urge Incontinence|Nocturia|Quality of Life|Voiding Disorders|Vagina Atrophy|Urethral Atrophy|Overactive Bladder|Overactive Bladder Syndrome|Bladder, Overactive
Interventions: DRUG: vaginal 17 beta-estradiol|DRUG: Placebo|BEHAVIORAL: Behavioral modifications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Tranexamic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Carbetocin Administration on Heart Rate When Given as an Infusion Versus as a Bolus.
Status: COMPLETED
Conditions: Cesarean Section Complications|Hemodynamic Instability
Interventions: DRUG: Carbetocin bolus|DRUG: Carbetocin infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Strategies to Reduce Contrast Medium in Spectral CT Pulmonary Angiography
Status: COMPLETED
Conditions: Pulmonary Embolism
Interventions: DIAGNOSTIC_TEST: Low iodine Spectral Detector CT Pulmonary Angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: tDCS and VI to Treat Neuropathic Pain and Function in SCI
Status: UNKNOWN
Conditions: SCI - Spinal Cord Injury
Interventions: DEVICE: tDCS+VI|DEVICE: tDCS Sham+VI Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Training on Postoperative Pain - A Solomon Four Group Design
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Pain|Inguinal Hernia Repair|Mindfulness Training
Interventions: OTHER: Mindfulness education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Different Doses of Dexmedetomidine Added to Bupivacaine in Transversus Abdominis Plane Block in Caesarean Delivery
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Dexmedetomidine 0.5 mcg|DRUG: Dexmedetomidine 1 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Co-transplantation of Mesenchymal Stem Cell Derived Exosomes and Autologous Mitochondria for Patients Candidate for CABG Surgery
Status: RECRUITING
Conditions: Myocardial Infarction|Myocardial Ischemia|Myocardial Stunning
Interventions: BIOLOGICAL: mitochondria and MSC-derived exosomes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMZ Plus Apatinib in Newly Diagnosed High-grade Glioma：RCT
Status: UNKNOWN
Conditions: Glioma
Interventions: DRUG: apatinib|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Morphine Modulation of The Brain's Pain Matrix
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Morphine|OTHER: orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer
Status: TERMINATED
Conditions: POLE Exonuclease Mutant Colon Cancer|Microsatellite Instability|Stage III Colon Cancer
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Using Self-adhering Flowable Resin Composite in Repairing Old Defective Resin Composite Restorations Over 18 Months Follow up. (A Randomized Clinical Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Occlusal Caries
Interventions: PROCEDURE: VertiseTM flowable composite (Kerr,USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Treatment of Docetaxel, Anthracycline and Cyclophosphamide (TAC) Versus Docetaxel and Cyclophosphamide (TC) in Triple-Negative or Her2 Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel, Anthracycline (Doxorubicin or Epirubicin), Cyclophosphamide|DRUG: Docetaxel, cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Spondyloarthritis|Systemic Lupus Erythematosus (SLE)|Dermatomyositis (DM)|DMixed Connective Tissue Disease|Systemic Vasculitis|Systemic Sclerosis (SSc)|Sjögren's Syndrome|Antiphospholipid Syndrome|Juvenile Idiopathic Arthritis|Juvenile SLE|Juvenile DM
Interventions: BIOLOGICAL: Anti-pandemic H1N1 influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pulsatile Perfusion Therapy Phase II
Status: COMPLETED
Conditions: Hemorrhage
Interventions: OTHER: 0 Hz Control|OTHER: 0.1 Hz PPT|OTHER: 0.05 Hz PPT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Curcumin in Treatment of Squamous Cervical Intraepithelial Neoplasias (CINs)
Status: UNKNOWN
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease
Status: RECRUITING
Conditions: Kidney Disease
Interventions: DRUG: Bremelanotide|DRUG: RAAS inhibition therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Living With Multimorbidity: CO-ORDINATE Program
Status: COMPLETED
Conditions: Multimorbidity|Quality of Life|Symptom Management
Interventions: OTHER: Care cO-ORDInatioN And sympTom managEment (CO-ORDINATE) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Danish National Randomized Study on Early Aortic Valve Replacement in Patients With Asymptomatic Severe Aortic Stenosis
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Diastolic Dysfunction
Interventions: PROCEDURE: Aortic valve replacement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
Status: RECRUITING
Conditions: Spinal Muscular Atrophy|Charcot-Marie-Tooth Disease|Muscular Dystrophy|Spinal Muscular Atrophy With Respiratory Distress 1|Amyotrophic Lateral Sclerosis|Motor Neuron Disease|Neuromuscular Disease|Peroneal Muscular Atrophy
Interventions: OTHER: sample collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Pharmacokinetics of Tezepelumab After Being Delivered by an Accessorized Pre Filled Syringe or Autoinjector Compared With Vial and Syringe in Healthy Adult Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: Tezepelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib in Treating Patients With Stage IIIB or Stage IV Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Bronchoalveolar Cell Lung Cancer|Non-small Cell Lung Cancer|Recurrent Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: My Journey: A Brief Contextual Behavioural Intervention Based on Meaning and Connection
Status: COMPLETED
Conditions: Social Media Addiction|Internet Gaming Disorder|Smartphone Addiction|Quality of Life|Psychological Distress
Interventions: BEHAVIORAL: A Brief Contextual Behavioural Intervention Based on Strengths, Meaning, Hope and Connection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Vancomycin-Associated Acute Kidney Injury: A Cross-Sectional Study From a Multi- Center in China
Status: UNKNOWN
Conditions: Vancomycin|Staphylococcal Infections|Adverse Effect|Acute Kidney Injury|Cross-sectional Study
Interventions: DRUG: Vancomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lapatinib and Topotecan in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin
Status: COMPLETED
Conditions: Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: DRUG: Lapatinib|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactulose vs. Polyethylene Glycol as Bowel Preparation for Colonoscopy in Adults
Status: COMPLETED
Conditions: Lactulose|Polyethylene Glycol|Bowel Preparation|Colonoscopy|Bisacodyl
Interventions: DRUG: Lactulose|DRUG: Polyethylene Glycol 3350
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy in cfHPV-DNA Plasma Positive Patients: A Biomarker In Locally Advanced Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer|Cervix Cancer|Cervix Neoplasm
Interventions: DRUG: cisplatin, gemcitabine|OTHER: Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microvascular Cardiac Allograft Vasculopathy Trial
Status: RECRUITING
Conditions: Cardiac Allograft Vasculopathy
Interventions: DIAGNOSTIC_TEST: Echocardiography|DIAGNOSTIC_TEST: Magnetic resonance imaging|DIAGNOSTIC_TEST: Magnetocardiography|DIAGNOSTIC_TEST: Histology|DIAGNOSTIC_TEST: Genetics|DIAGNOSTIC_TEST: calcium signaling|DIAGNOSTIC_TEST: IMR|DIAGNOSTIC_TEST: Angio-IMR
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance of Toric Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Astigmatism|Myopia
Interventions: DEVICE: Lens A (fanfilcon A)|DEVICE: Lens B (asmofilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiofrequency Ablation Versus Stereotactic Radiotherapy in Colorectal Liver Metastases
Status: TERMINATED
Conditions: Colorectal Carcinoma|Liver Metastases
Interventions: PROCEDURE: SBRT or RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arterial Access for Coronary Intervention in Myocardial Infarction
Status: COMPLETED
Conditions: Myocardial Infarction|Angioplasty, Transluminal, Percutaneous Coronary|Myocardial Reperfusion
Interventions: PROCEDURE: Coronary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acetaminophen Versus Ibuprofen for the Control of Immediate and Delayed Pain Following Orthodontic Separator Placement
Status: COMPLETED
Conditions: Orthodontic Pain
Interventions: DRUG: Acetaminophen|DRUG: Avicel (placebo)|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minocycline to Treat Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Retinal Vein Occlusion
Interventions: DRUG: Minocycline|DRUG: Placebo|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: N-terminal Pro B-type Natriuretic Peptide (Nt-proBNP) Versus Exercise Test for Evaluation of Acute Chest Pain
Status: COMPLETED
Conditions: Chest Pain
Interventions: OTHER: Exercise testing|OTHER: Clinical evaluation + NTproBNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Role of Virtual Reality in Hand Rehabilitation for Children With Cerebral Palsy
Status: COMPLETED
Conditions: Physical Disability|Cerebral Palsy
Interventions: DEVICE: Leap Motion Sensor|OTHER: Neurodevelopmental Treatment Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Levonorgestrel-releasing Intrauterine System Versus a Low-dose Combined Oral Contraceptive for Management of Adenomyosis Uteri
Status: UNKNOWN
Conditions: Adenomyosis
Interventions: DRUG: Yasmin|DEVICE: Metraplant-E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE