pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: SDF1 Plasmid Treatment for Patients With Peripheral Artery Disease
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: BIOLOGICAL: JVS-100|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurocognitive Outcomes In Patients Treated With Radiotherapy For Five Or More Brain Metastases
Status: WITHDRAWN
Conditions: Brain Metastases
Interventions: RADIATION: Stereotactic radiosurgery (SRS)|RADIATION: Whole brain radiation therapy (WBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized tDCS in Elderly Fallers Study
Status: RECRUITING
Conditions: Accidental Falls|Aging
Interventions: OTHER: Personalized tDCS|OTHER: Active-Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Lidocaine for Post-Operative Pain Control in Patients Undergoing Bariatric Bowel Surgery
Status: WITHDRAWN
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Low Dose Lidocaine|DRUG: High Dose Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Outcomes of CT-FFR Versus QFR-guided Strategy for Decision-Making in Patients With Stable Chest Pain
Status: NOT_YET_RECRUITING
Conditions: Angina, Stable|Coronary Artery Disease
Interventions: DEVICE: CT-FFR|DEVICE: QFR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: " Effect of Affordance of Objects on the Memory: Study in Transcranial Magnetic Stimulation "
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: PMv stimulation (iTBS)|OTHER: PMv inhibition (cTBS)|OTHER: Control (SHAM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Chinese Registration Study of Driver Ablation of Persistent Atrial Fibrillation.
Status: COMPLETED
Conditions: Atrial Fibrillation, Persistent
Interventions: PROCEDURE: Driver ablation+CPVI|PROCEDURE: Stepwise ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HandiHaler® vs. Metered Dose Inhaler (MDI) in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: Placebo capsule administered via the HandiHaler®|DEVICE: Ipratropium metered dose inhaler (MDI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Urinary Bladder Dissection During Total Laparoscopic Hysterectomy in Cases With Previous Cesarean Section
Status: RECRUITING
Conditions: Total Laparoscopic Hysterectomy
Interventions: PROCEDURE: central urinary bladder dissection|PROCEDURE: Lateral urinary bladder dissection|DEVICE: Wolf laparoscopy tower
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Support of Colonization Resistance of the Gut Microbiota With the Synbiotic Food Supplement Nagasin®
Status: RECRUITING
Conditions: C. Difficile Enteritis
Interventions: DIETARY_SUPPLEMENT: Nagasin|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Ropinirole 0.25 mg Tablets Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ropinirole HCl 0.25 mg Tablets|DRUG: Requip® 0.25 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Left Atrial Appendage Electrical Isolation in Persistent Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation|Left Atrial Appendage|Left Atrial Appendage Occlusion|Catheter Ablation
Interventions: PROCEDURE: Catheter ablation and left atrial appendage occlusion|PROCEDURE: Additional left atrial appendage electrical isolation combined with catheter ablation and left atrial appendage occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
Status: COMPLETED
Conditions: HIV Infections|Depression|Mild Cognitive Impairment
Interventions: DRUG: raltegravir single dose|DRUG: ginkgo biloba multiple dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Meditoxin® Treatment in Patients With Post Stroke Upper Limb Spasticity
Status: COMPLETED
Conditions: Muscle Spasticity
Interventions: DRUG: Ultrasonography guidance injection of Meditoxin®.|DRUG: Electrical stimulation guidance injection of Meditoxin®.|DRUG: Manual needle placement injection of Meditoxin®.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single and Multiple Ascending Doses of ARGX-119 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase3 Study of Amrubicin With Cisplatin Versus Etoposide-cisplatin for Extensive Disease Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Amrubicin Hydrochloride|DRUG: Etoposide-Cisplatin combined chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: BIOLOGICAL: BCG intravesical live (TICE Bacillus Calmette-Guerin (BCG))|BIOLOGICAL: PANVAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Based on Japanese Medical Records That Looks at Bleeding Events in People With Atrial Fibrillation and Coronary Artery Disease Who Start Taking Either Dabigatran, Rivaroxaban, or Warfarin
Status: COMPLETED
Conditions: Coronary Artery Disease|Atrial Fibrillation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TOFO Insulin Combination Trial
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TOFOGLIFLOZIN CSG452|DRUG: insulin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Computerized Cognitive Training in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Cognitive Change|Cognitive Impairment|Quality of Life
Interventions: BEHAVIORAL: Sweep Seeker|BEHAVIORAL: Bird Safari|BEHAVIORAL: Jewel Diver|BEHAVIORAL: Master Gardener|BEHAVIORAL: Road Tour|BEHAVIORAL: Computerized Crossword Puzzles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of a PST-Trained Voice-Enabled Artificial Intelligence Counselor (SPEAC) for Adults With Emotional Distress (Phase 1)
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Lumen Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Intervention of Obesity in Children With Prader-Willi Syndrome Using Prebiotics and Probiotics
Status: RECRUITING
Conditions: Prader-Willi Syndrome
Interventions: DIETARY_SUPPLEMENT: probiotics including B. lactis B420, B. lactis HN019, B. animalis Bb-12, L. rhamnosus GG|DIETARY_SUPPLEMENT: Prebiotics with galactomannan and oligofructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Observations of Pain and Pruritus Induced by Exposure to Allergic Contact Dermatitis Caused by Macrolides
Status: NOT_YET_RECRUITING
Conditions: Dermatitis, Allergic Contact
Interventions: DRUG: Erythromycin|DRUG: Azithromycin|OTHER: physiological saline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trunk Task-oriented Training Combined With Functional Electrical Stimulation in Spinal Cord Injured Individuals
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: OTHER: Trunk-oriented task training combined with functional electrical stimulation|OTHER: Trunk-oriented task training alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Ranibizumab|PROCEDURE: Laser|PROCEDURE: Sham laser|DRUG: Sham to ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Tolerability and Determining the PK and PD of Single Dose UB-221 in Chronic Spontaneous Urticaria
Status: NOT_YET_RECRUITING
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: UB-221
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Grape Powder Consumption on Eye Health and Glycemic Status in Singapore Older Adults
Status: NOT_YET_RECRUITING
Conditions: Macula; Degeneration|Aging|Advanced Glycation End Products
Interventions: DIETARY_SUPPLEMENT: Freeze-dried table grape powder|DIETARY_SUPPLEMENT: Placebo grape powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART)
Status: COMPLETED
Conditions: Polycystic Ovarian Syndrome
Interventions: DRUG: Cetrorelix acetate|DRUG: Cetrorelix acetate|DRUG: Recombinant Human Choriogonadotropin (r-hCG)|DRUG: Recombinant human follicle stimulating hormone (r-hFSH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Metabolic & Mental Health in Female Healthcare Shift Workers
Status: ACTIVE_NOT_RECRUITING
Conditions: Sleep, Inadequate|Overweight and Obesity|Work Related Stress|Healthy Lifestyle
Interventions: BEHAVIORAL: Lifestyle Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Intra-alveolar Application of Honey on Healing Following Extraction
Status: UNKNOWN
Conditions: Dry Socket
Interventions: PROCEDURE: Tooth extraction|DRUG: Chlorhexidine mouth wash|DRUG: Intra-alveolar application of Manuka Honey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triton Fundus Autofluorescence and Fluorescein Angiography
Status: COMPLETED
Conditions: Medical Need for Fluorescein Angiography Imaging
Interventions: DEVICE: Topcon DRI OCT Triton (plus)|DEVICE: TRC-50DX retinal camera
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PREVACT : Preventive REversal of Vitamine K Antagonist in Minor Craniocerebral Trauma
Status: TERMINATED
Conditions: Coagulation; Intravascular|Craniocerebral Trauma|Haemorrhage
Interventions: DRUG: Reversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collagen Vitamin C Dose Response Performance
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: Hydrolyzed collagen|DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: Optimized Hydrolyzed Collagen and Vitamin C|DIETARY_SUPPLEMENT: Gummy Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab in Treating Patients With Relapsed Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer|Stage III Prostate Cancer
Interventions: BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correct Endotracheal Tube Position in Newborns Intubated in the Delivery Room
Status: UNKNOWN
Conditions: Intubation Complication|Newborn Morbidity|Cardiopulmonary Resuscitation
Interventions: PROCEDURE: ETT insertion depth using Spanish recommendations|PROCEDURE: ETT insertion depth using international recommendations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Engaged4Life Study: Enhancing the Health-Promoting Effects of Older Adults' Activity Portfolios
Status: COMPLETED
Conditions: Sedentary Lifestyle
Interventions: BEHAVIORAL: Technology-assisted self-monitoring|BEHAVIORAL: Workshop and Peer Mentoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Standard vs Higher Starting Dose of Insulin Glargine in Chinese Patients With Type 2 Diabetes (Glargine Starting Dose)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: INSULIN GLARGINE|DRUG: metformin|DRUG: acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPI-613 (Devimistat) in Combination With Modified FOLFIRINOX Plus Bevacizumab in Patients With Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: C04.588.274.476.411.307
Interventions: DRUG: CPI-613|DRUG: modified FFX|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Motor and Sensory Response With Interstim Stimulation
Status: COMPLETED
Conditions: Overactive Bladder|Urgency-Frequency
Interventions: DEVICE: Interstim implant for SNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of the Efficacy of Rapid Tests to Identify COVID-19 Infection (CATCh COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: DIAGNOSTIC_TEST: diagnostic tests for COVID-19 infection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY Trial
Status: RECRUITING
Conditions: Castration-Sensitive Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: Antiandrogen Therapy|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|DRUG: Cytotoxic Chemotherapy|PROCEDURE: FDG-Positron Emission Tomography|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess Hematologic Response in Patients With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndromes Undergoing Monotherapy With Exjade (Deferasirox)
Status: COMPLETED
Conditions: High Risk MDS or AML Patients
Interventions: DRUG: Exjade® (deferasirox, ICL670)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy for Patients With Advanced Gastric Cancer in ERAS Programs for Radical Gastrectomy
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: NAC group|PROCEDURE: Surgery alone group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiological Study to Assess the Prevalence of Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer|Tobacco|Atherosclerotic Cardiovascular Event
Interventions: OTHER: low dose CT scan|OTHER: blood sample collection|OTHER: faecal sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Resident-Performed Laser-Assisted vs Manual Traditional Phacoemulsification Cataract Surgery
Status: COMPLETED
Conditions: Incipient Cataract|Senile Nuclear Sclerosis
Interventions: PROCEDURE: Laser-assisted cataract surgery.|PROCEDURE: Traditional manual phacoemulsification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Support Application for Food Pantries (SAFPAS) to Improve Client Access to Healthy Foods & Enhance Emergency Preparedness
Status: RECRUITING
Conditions: Improving Healthy Food Access in Food Insecurity Populations in Normal and Emergency Situations
Interventions: BEHAVIORAL: Support Application for Food PAntrieS (SAFPAS) - A mobile app that helps food pantries recruit, train and schedule volunteers, offer choice safely, and provides multilevel communications
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigation of the Benefits of Electrical Non-invasive Stimulation on Cognitive Symptoms in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: OTHER: Neuropsychological assessment|OTHER: Neurological assessment|OTHER: Cognitive task|PROCEDURE: EEG|PROCEDURE: tACS (real or sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: PEmbRolizumab verSus chEmotherapy and pEmbrolizumab in Non-small-cell Lung Cancers (NSCLC) With PDL1 ≥ 50 %
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Pembrolizumab and Chemotherapy drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ABT-333 in Both Healthy Volunteers and Hepatitis C Virus (HCV) + Genotype 1 Infected Subjects
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ABT-333|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Human Plasma Protein Transfusion With and Without Crystalloids During Major Liver Resection Surgeries
Status: UNKNOWN
Conditions: Coagulation; Intravascular|Fluid Electrolyte Disorders
Interventions: DRUG: 5% human plasma protein fraction (PPF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Atomoxetine in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Atomoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Temporal Memory in Schizophrenic Patients
Status: RECRUITING
Conditions: Patients With Schizophrenia
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)- anodal group|DEVICE: Transcranial direct current stimulation (tDCS)- sham group|DEVICE: transcranial alternating current stimulation (tACS)-tACS group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of PCA on PONV After Microvascular Decompression
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: NSAID|DRUG: Opioid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Novel Volumetric Analysis Using CAD/CAM Scanners in Gingival Recession Treatment
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: SCTG+EMD|PROCEDURE: SCTG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)
Status: RECRUITING
Conditions: Glioblastoma Multiforme of Brain
Interventions: BIOLOGICAL: TVI-Brain-1|PROCEDURE: Standard of Care|RADIATION: Radiotherapy|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Hip Arthroplasty
Status: RECRUITING
Conditions: Hip Osteoarthritis|Hip Arthropathy|Hip Pain Chronic
Interventions: DRUG: 0.9%sodium chloride|DRUG: Dexamethasone|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Versus Cyclic Use of Oral Contraceptive Pills in Adolescents
Status: UNKNOWN
Conditions: Contraception
Interventions: DRUG: Desogestrel-Ethinyl Estradiol 21 tablets|DRUG: Desogestrel-Ethinyl Estradiol 28 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study Between Lamivudine Formulations in the Form of Coated Tablet of 150 mg in Healthy Volunteers
Status: COMPLETED
Conditions: HIV INFECTIONS
Interventions: DRUG: Epivir ® tablet 150-mg single dose (drug reference)|DRUG: Lamivudine 150-mg tablet single dose (drug test)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of 8 Weeks Post Exercise Hot Water Immersion on Vascular and Cardiometabolic Health in Physically Inactive Middle-aged Adults
Status: COMPLETED
Conditions: Physical Inactivity|Aging
Interventions: OTHER: Aerobic exercise + hot water immersion|OTHER: Aerobic exercise + thermoneutral water immersion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: To Assess Safety, Tolerability and Pharmacokinetics of BI 730357 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: BI 730357|DRUG: BI 730357
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Adalimumab Versus Subcutaneous Adalimumab in Non-infectious Uveitis
Status: RECRUITING
Conditions: Uveitis|Non-Infectious Uveitis
Interventions: DRUG: Adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib and Erlotinib or Sorafenib Alone in Advanced Non-Small Cell Lung Cancer Progressing on Erlotinib
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Sorafenib|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: From Preserved, to Preservative-free Cyclosporine 0.1% Enhanced Triple Glaucoma Therapy
Status: COMPLETED
Conditions: Glaucoma|Ocular Surface Disease
Interventions: DIAGNOSTIC_TEST: Assessment of ocular surface staining (Oxford score 0-15 scale)|DRUG: mean diurnal intraocular pressure-lowering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure)
Status: COMPLETED
Conditions: Heart Failure, Congestive|Edema
Interventions: DRUG: OPC-41061(Tolvaptan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Patient-therapist INTERaction During RObotic GAIT Rehabilitation After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Lokomat Robot Assisted Gait Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement of the Nutritional Status Regarding Nicotinamide (Vitamin B3) and the Disease Course of COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: Nicotinamide|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Naftopidil in Patient With Neurogenic Lower Urinary Tract Dysfunction Not Caused by Benign Prostatic Hyperplasia
Status: COMPLETED
Conditions: Neurogenic Lower Urinary Tract Dysfunction
Interventions: DRUG: Naftofidil|DRUG: Tamsulosin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure
Status: COMPLETED
Conditions: Acute Liver Failure|Hepatic Encephalopathy|Intracranial Hypertension
Interventions: DEVICE: Prometheus (R) liver support dialysis|DEVICE: CVVHDF (Continuously Veno-Venous Hemodiafiltration)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant
Status: RECRUITING
Conditions: Recurrent Hepatocellular Carcinoma|Stage III Hepatocellular Carcinoma AJCC v8|Stage IIIA Hepatocellular Carcinoma AJCC v8|Stage IIIB Hepatocellular Carcinoma AJCC v8|Stage IV Hepatocellular Carcinoma AJCC v8|Stage IVA Hepatocellular Carcinoma AJCC v8|Stage IVB Hepatocellular Carcinoma AJCC v8|Unresectable Hepatocellular Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI-enabled Endoscopic Prediction of Post-operative Recurrence in Crohn's Disease
Status: RECRUITING
Conditions: Crohn Disease
Interventions: PROCEDURE: Colonoscopy|PROCEDURE: Intestinal biopsies|PROCEDURE: Confocal laser endomicroscopy|PROCEDURE: Intestinal ultrasound|DIAGNOSTIC_TEST: Stool|DIAGNOSTIC_TEST: Blood|DIAGNOSTIC_TEST: Saliva|OTHER: Clinical follow-up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Community Effectiveness of IPTi in Southern Tanzania
Status: UNKNOWN
Conditions: Malaria, Falciparum|Anemia
Interventions: DRUG: Sulfadoxine-pyrimethamine used for IPTi|DRUG: IPTi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial to Assess the Effect of Liraglutide on Blood Triglyceride (Fat) Levels After a Meal in Type 2 Diabetics
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Duration of Treatment Interruption With or Without Curcumin During the Off Treatment Periods in Patients With Prostate Cancer Undergoing Intermittent Androgen Deprivation Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: curcumin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ENCOMPASS: Expansion Study A, RCT
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Chronic Kidney Diseases|Ischemic Heart Disease|Congestive Heart Failure|Chronic Obstructive Pulmonary Disease|Asthma
Interventions: BEHAVIORAL: Community Health Navigator Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of Providing Free Samples of Generic Cardiovascular Medications to Physicians
Status: UNKNOWN
Conditions: Hypertension|Hyperlipidemia
Interventions: BEHAVIORAL: Free Generic Samples (hydrochlorothiazide, simvastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Multimodal Image Processing Software to Guide Cardiac Ablation Therapy
Status: COMPLETED
Conditions: Ventricular Arrhythmias|Persistent Atrial Fibrillation
Interventions: DEVICE: Contrast-enhanced ECG-gated multi-detector computed tomography|DEVICE: Magnetic resonance imaging|DEVICE: Positron emission tomography|DEVICE: Body surface mapping|PROCEDURE: Cardiac ablation procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: TCF-001 TRACK (Target Rare Cancer Knowledge) Study
Status: RECRUITING
Conditions: Rare Cancers|Cholangiocarcinoma|Cancer of Unknown Primary Site
Interventions: DIAGNOSTIC_TEST: FoundationOne CDx and FoundationOne Liquid CDx
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of γ-linolenic Acid and Thioctic Acid in Patients With Diabetic Neuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathy
Interventions: DRUG: γ-linoleic acid and placebo(Thioctic Acid)|DRUG: Thioctic Acid and placebo(γ-linoleic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Mindful Prevention of Psychopathology in Healthcare Workers During the COVID-19 Crisis (COVID-19 MindPreP)
Status: COMPLETED
Conditions: Mindfulness|Randomized Controlled Trial|Psychopathology|Health Personnel
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction|OTHER: Self-help mindfulness/compassion exercises|OTHER: Support as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Tremelimumab and Durvalumab (MEDI4736) (T300+D) in Advanced Hepatocellular Carcinomas With Child-Pugh-B Cirrhosis
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|Cirrhosis, Liver
Interventions: DRUG: Tremelimumab|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Micronutrient Supplementation on Gut Microbiome Composition and Function
Status: UNKNOWN
Conditions: Gastrointestinal Microbiome
Interventions: DIETARY_SUPPLEMENT: Multivitamin Supplementation|OTHER: Dietary Replication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does Injection Site Matter? A Randomized Controlled Trial to Evaluate Efficacy of Knee Intraarticular Injections on Improval of Patient Reported Outcomes.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: Depomedrol|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of PEG-rhG-CSF（Pegylated Recombinant Human Granulocyte Colony Stimulating Factor)in Patients With Breast Cancer Who Were Treated With Intensive Chemotherapy
Status: COMPLETED
Conditions: Breastcancer
Interventions: DRUG: PEG-rhG-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Auricular Acupressure in Treating Allergic Rhinitis
Status: RECRUITING
Conditions: Itching|Runny Nose|Sneezing|Nasal Congestion
Interventions: OTHER: Auricular acupressure|OTHER: Sham acupressure|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study Testing Onabotulinum Toxin A Versus Incobotulinum Toxin A Injections for Facial Wrinkles
Status: ACTIVE_NOT_RECRUITING
Conditions: Wrinkles
Interventions: DRUG: Onabotulinum Toxin A|DRUG: Incobotulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rotablator on Balloon Resistant Calcified Coronary Lesion
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Rotablator|PROCEDURE: conventional angioplasty|PROCEDURE: stenting|DEVICE: Cutting balloon|DRUG: Aspirin|DRUG: Clopidogrel|DEVICE: Paclitaxel-eluting stent|DEVICE: zotarolimus-eluting stent|DEVICE: Everolimus-eluting stent|DEVICE: Sirolimus-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nebulized Beclometasone Dipropionate Improves Nasal Patency in Children With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Nasal Beclomethasone Dipropionate|DRUG: CERCHIO 10 mg/ml OS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antimicrobial-free Production of Beef Cattle's Affect on Gut Microbiome
Status: COMPLETED
Conditions: Diet Modification
Interventions: OTHER: Controlled diet with beef raised without antibiotics|OTHER: Controlled diet with beef produced in conventional systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Arsenic Trioxide in Combination With Cytarabine in Patients With High-risk MDS and Poor-prognosis AML
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: Arsenic Trioxide (Tricenox)|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet Alfa
Status: COMPLETED
Conditions: Bleeding
Interventions: BIOLOGICAL: Andexanet alfa (Gen 1 Process 2)|DRUG: Apixaban 5 MG|DRUG: Rivaroxaban 20 MG|DRUG: Enoxaparin sodium|DRUG: Edoxaban 60 MG|BIOLOGICAL: Andexanet alfa (Gen 2)|BIOLOGICAL: Andexanet alfa (Gen 1 Process 3)|DRUG: Apixaban 10 MG|DRUG: Rivaroxaban 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Status: RECRUITING
Conditions: Stereotypical Prolonged Seizures
Interventions: DRUG: Staccato alprazolam|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an App-based CBT Featuring Virtual Reality for Anxiety Disorders
Status: UNKNOWN
Conditions: Anxiety|Social Phobia|Panic Disorder|Agoraphobia
Interventions: COMBINATION_PRODUCT: ALISA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intraosseous Periodontal Defects With Amelogenins
Status: RECRUITING
Conditions: Periodontal Bone Loss|Periodontal Pocket
Interventions: OTHER: MINSD and amelogenins|OTHER: MINSD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Omalizumab in Severe Japanese Cedar Pollinosis Adult and Adolescent Patients
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Standard and Robot Assisted Total Knee Arthroplasty With a Bicrucatie Retaining Prosthesis
Status: RECRUITING
Conditions: Osteo Arthritis Knee
Interventions: PROCEDURE: Total Knee Prosthesis - type Bicruciate retaining|PROCEDURE: Robot-assisted Total Knee Arthroplasty|PROCEDURE: Total Knee Prosthesis - type Posterior Stabilized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
Status: COMPLETED
Conditions: Surgical Site Infection|Unplanned Fracture-Related Reoperation|Open Appendicular Fracture
Interventions: DRUG: 10% povidone-iodine (1% free iodine) in purified water|DRUG: 4% chlorhexidine gluconate (CHG) in purified water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: tauroursodeoxycholic acid (TUDCA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Endostar Combined With Taxane-based Regimens for HER-2-negative MBC Patients
Status: UNKNOWN
Conditions: Angiogenesis|Breast Cancer
Interventions: DRUG: endostar
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GDC-0980 in Combination With a Fluoropyrimidine, Oxaliplatin, and Bevacizumab in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Cancers
Interventions: DRUG: GDC-0980|DRUG: bevacizumab|DRUG: capecitabine|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Zinc in Childhood Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Zinc (zinc sulphate)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: TERMINATED
Conditions: Hormone-Resistant Prostate Cancer|Metastatic Malignant Neoplasm in the Bone|Metastatic Prostate Carcinoma
Interventions: PROCEDURE: Contrast-enhanced Magnetic Resonance Imaging|DRUG: Fludeoxyglucose F-18|DRUG: Fluorine F 18 Sodium Fluoride|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Abicipar Pegol in Japanese Patients With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: DRUG: abicipar pegol|DRUG: ranibizumab|OTHER: sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Patients' Satisfaction Between Dexmedetomidine and Remimazolam Anesthesia in Patients With Atrial Fibrillation Undergoing Catheter Ablation
Status: RECRUITING
Conditions: Patients With Atrial Fibrillation Undergoing Catheter Ablation
Interventions: DRUG: remimazolam-remifentanil|DRUG: dexmedetomidine-remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficiency and Safety of Nasal Positive Airway Pressure Systems During Endoscopy
Status: COMPLETED
Conditions: Hypercapnia|Hypoxia
Interventions: DEVICE: Nasal positive airway System by Vyaire Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Tofacitinib in Depression (TIDE)
Status: TERMINATED
Conditions: Depression|Inflammation
Interventions: DRUG: Tofacitinib 5 MG [Xeljanz]|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of a Novel Non-diffractive Extended Depth of Focus Intraocular Lens (IOL) and a Trifocal IOL
Status: COMPLETED
Conditions: Intraocular Lens|Cataract|Quality of Life
Interventions: DEVICE: İntraocular lens implantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Outcome Comparisons of Vibratory Airway Clearance Devices
Status: RECRUITING
Conditions: Airway Clearance Impairment
Interventions: DEVICE: High Oscillatory Index Device|DEVICE: Low Oscillatory Index Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vibration and Shotblocker Use in Pregnant Women While Giving Tetanus + Diphtheria Vaccine
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: OTHER: Local mechanical vibration|OTHER: Shotblocker group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Effectiveness of Anti-HIV Vaccines in HIV-Negative Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: ALVAC(2)120(B,MN)GNP (vCP1452)|BIOLOGICAL: gp160 MN/LAI-2|BIOLOGICAL: ALVAC(1)120(B,MN)GNP (vCP1433)|BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|BIOLOGICAL: ALVAC-RG Rabies Glycoprotein (vCP65)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Scapular Muscles Training Using a Suspension System in Patients With Non Spacific Chronic Neck Pain and Scapular Dyskinesia
Status: COMPLETED
Conditions: Scapular Dyskinesis
Interventions: DEVICE: Suspension system|OTHER: Scapular training exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Pharmacodynamics of Phentermine-Topiramate in Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Phentermine-Topiramate ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fluorodopa F 18 in Congenital Hyperinsulinism and Insulinoma
Status: RECRUITING
Conditions: Congenital Hyperinsulinism|Insulinoma
Interventions: DRUG: Fluorodopa F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Outcomes Among Persons With Schizophrenia Under the Peer-support Service in Vocational Rehabilitation Program
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: peer co-delivered vocational rehabilitation service
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cervical and Endometrial Injection for Sentinel Lymph Node Detection in Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer|Sentinel Lymph Node
Interventions: PROCEDURE: Transcervical endometrial injection of technetium 99 m-labeled human albumin colloid particles|PROCEDURE: Cervical injection of technetium 99 m-labeled human albumin colloid particles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC