pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combination Chemotherapy With or Without Capecitabine and/or Trastuzumab Before Surgery in Treating Women With Stage I, Stage II, or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: capecitabine|DRUG: cyclophosphamide|DRUG: docetaxel|DRUG: epirubicin hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Reintubation by Using Noninvasive Positive Pressure Ventilation
Status: UNKNOWN
Conditions: Extubation Failure|Acute Respiratory Failure Post Extubation
Interventions: OTHER: Positive Pressure Noninvasive ventilation|OTHER: Inhalatory O2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites
Status: RECRUITING
Conditions: Wound Heal
Interventions: DEVICE: Porcine Collagen Membrane|DEVICE: Bovine Collagen Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder in Children|Social Anxiety Disorder of Childhood|Obsessive-Compulsive Disorder in Adolescence|Separation Anxiety|Generalized Anxiety Disorder|Panic Disorder|Panic Attacks|Panic With Agoraphobia
Interventions: BEHAVIORAL: Standard SPACE|BEHAVIORAL: Bibliotherapy, low therapist contact SPACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacists Interventions on Patients Diabetic, and Obese Patients in the UAE: Randomized Controlled Trials.
Status: UNKNOWN
Conditions: Hypertension|Diabete Type 2|Obesity|Pharmacist-Patient Relations
Interventions: BEHAVIORAL: Pharmaceutical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Role of EndoFLIP in the Diagnostic Paradigm of Esophagogastric Junction Outflow Obstruction
Status: UNKNOWN
Conditions: Esophagogastric Junction Disorder
Interventions: DRUG: Botulinum Toxin Type A Injection [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Liver Cancer and Immunotherapy in the Liquid Biopsy Era
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma|BCLC Stage B Hepatocellular Carcinoma|BCLC Stage C Hepatocellular Carcinoma|Immune Checkpoint Inhibitor|Liquid Biopsy
Interventions: BIOLOGICAL: Liquid Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Irinotecan Plus ICI D1694 in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: raltitrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Does Improvement Towards a Normal Cervical Sagittal Configuration Aid in the Management of Lumbosacral Radiculopathy
Status: COMPLETED
Conditions: Cervical Lordosis Rehabilitation
Interventions: OTHER: Deneroll cervical extension traction|OTHER: Traditional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Detection of Extravascular Lung Water Increase During Weaning From Mechanical Ventilation
Status: COMPLETED
Conditions: Ventilator Weaning
Interventions: OTHER: Monitoring of pulmonary oedema induced by weaning from mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Evaluate Blister Graft Utilizing a Novel Harvesting Device for Treatment of Venous Leg Ulcers
Status: TERMINATED
Conditions: Impaired Wound Healing|Venous Insufficiency of Leg|Diabetic Ulcers
Interventions: DEVICE: Harvesting Device (CelluTome©)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF CANCER EDUCATION ON WOMEN'S AWARENESS LEVELS AND THEIR BEHAVIORS ON SCREENINGS
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: HEALTH FAITH MODEL GUIDED IN CANCER FREQUENTLY SEEN IN WOMEN EARLY DIAGNOSIS AND SCREENING METHODS EDUCATION|BEHAVIORAL: STANDART CANCER EDUCATİON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Financial Navigation Intervention in Improving Financial and Clinical Outcomes in Patients With Newly Diagnosed Gastric or Gastroesophageal Junction Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma
Interventions: OTHER: Media Intervention|OTHER: Informational Intervention|OTHER: Best Practice|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Study of Microbial Ecosystem Therapeutics (MET-4) to Evaluate Effects of Fecal Microbiome in Patients on ImmunOtherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: All Solid Tumors
Interventions: BIOLOGICAL: MET-4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An AI Platform Integrating Imaging Data and Models, Supporting Precision Care Through Prostate Cancer's Continuum
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Cancer Metastatic|Prostate Cancer Recurrent|Prostate Cancer Aggressiveness
Interventions: DIAGNOSTIC_TEST: Magnetic Resonance Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Study of MDX-010 (CTLA-4) Alone and Combined With DTIC in the Treatment of Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: MDX-010 (CTLA-4)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate Analgesic Efficacy of Fast Release Aspirin
Status: COMPLETED
Conditions: Drugs, Investigational
Interventions: DRUG: Acetylsalicyclic acid (Fast acting Aspirin, BAY1019036)|DRUG: Acetylsalicyclic acid (Aspirin, BAYE4465)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)
Status: COMPLETED
Conditions: Ischemic Heart Disease
Interventions: OTHER: Inhaled anaesthetic agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock
Status: UNKNOWN
Conditions: Septic Shock|Platelet Signal Processing Defect|Inflammatory Response|Disseminated Intravascular Coagulation|Covid19|Neutrophil Extracellular Trap Formation
Interventions: OTHER: Assessment of coagulopathy, Platelets activation and Platelets-Neutrophils interplay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cervical Preparation in Hysteroscopy
Status: UNKNOWN
Conditions: GYN Disorders
Interventions: DRUG: misoprostol|DRUG: dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Radial and Focused Extracorporeal Shock Wave Therapies on Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis|Pain
Interventions: DEVICE: Extracorporeal shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elastic Band-Progressive Resistance Training (EB-PRT) for Sarcopenia Among Heart Failure Patients
Status: RECRUITING
Conditions: Heart Failure
Interventions: BEHAVIORAL: Elastic band-based progressive resistance training (EB-PRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography
Status: COMPLETED
Conditions: Respiratory Failure|Circulatory Failure|Fluid Responsiveness|Fluid Overload
Interventions: OTHER: Fluid Challenge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electrical Muscle Stimulation Versus Resistive Training On Physical Measures, And Fatigue In Hemodialysis Patients
Status: RECRUITING
Conditions: Hemodialysis|Fatigue
Interventions: DEVICE: Neuromuscular Electrical Stimulation|OTHER: resistive training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Added Value of Preoperative Contrast Enhanced Mammography in Staging of Malignant Breast Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Contrast Enhanced Mammography (CEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of scFOS on Increase in Stool Frequency in Constipated People
Status: COMPLETED
Conditions: Functional Constipation|Healthy
Interventions: DIETARY_SUPPLEMENT: scFOS|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp
Status: RECRUITING
Conditions: Actinic Keratoses
Interventions: COMBINATION_PRODUCT: BF-200 ALA and red light LED lamp|COMBINATION_PRODUCT: Vehicle and red light LED lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of NM/CT 870 DR Camera in the Diagnosis of Joint Prosthesis and Tibial Open Reduction and Internal Fixation (ORIF) Complications.
Status: UNKNOWN
Conditions: Bone Infection
Interventions: OTHER: Bone Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Placebo-Controlled Study to Assess the Efficacy of Propantheline for the Treatment of Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder Associated With HTLV-1
Interventions: DRUG: Propantheline Bromide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging
Status: RECRUITING
Conditions: Healthy Elderly Volunteers
Interventions: DIETARY_SUPPLEMENT: Nicotinamide Riboside|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Air Purifier to Improve Endothelial Function and Carotid Intima Thickness
Status: COMPLETED
Conditions: Endothelial Function|Cognitive Impairment
Interventions: DEVICE: Air purifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Backwards Walking Programme Following Hip and Knee Arthroplasty
Status: COMPLETED
Conditions: Hip Osteoarthritis|Knee Osteoarthritis|Hip Arthroplasty|Knee Arthroplasty
Interventions: OTHER: Backwards Walking (BW) programme|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project Arthritis Recovering Quality of Life Through Education 70+
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: OTHER: Multiprofessional treatment and Educational Program Associated (EPA+C+BCAA) with supplementation of creatine and BCAA.|OTHER: Multiprofessional treatment and Educational Program Associated (EPA+C) with supplementation of creatine only.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Trial of Luitpold Azacitidine Versus Vidaza® in Patients With Myelodysplastic Syndrome, Myelofibrosis, Chronic Myeloid Leukemia or Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|Myelofibrosis|Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia
Interventions: DRUG: Luitpold Azacitidine|DRUG: Vidaza®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity
Status: COMPLETED
Conditions: Upper Limb Spasticity
Interventions: BIOLOGICAL: DAXI for injection 250 U|BIOLOGICAL: DAXI for injection 375 U|BIOLOGICAL: DAXI for injection 500 U|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients
Status: COMPLETED
Conditions: Respiratory Failure|All Intubated Patients
Interventions: DEVICE: Adaptive Support Ventilation|DEVICE: Pressure Controlled Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Capsaicin 0.1%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: PLX3397|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Early Integrated Intervention for Child Brain-developmental Disorders in China
Status: COMPLETED
Conditions: Brain Developmental Diseases|Autism Spectrum Disorder|Global Developmental Delay|Attention Deficit-Hyperactivity Disorder
Interventions: BEHAVIORAL: The early integrated intervention for GDD|BEHAVIORAL: The early integrated intervention for ASD|BEHAVIORAL: The early integrated intervention for ADHD|BEHAVIORAL: community intervention for ASD|BEHAVIORAL: Community intervention for GDD|BEHAVIORAL: community intervention for ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Switching From Regimens Consisting of a Nonnucleoside Reverse Transcriptase Inhibitor Plus Emtricitabine and Tenofovir DF to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected Patients
Status: COMPLETED
Conditions: Acquired Immunodeficiency Syndrome|HIV Infections
Interventions: DRUG: NNRTI|DRUG: FTC/TDF|DRUG: Stribild
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gentle Human Touch and Kangaroo Care on Pain and Crying Physiological Parameters During Hepatitis-B Vaccination in a Newborn
Status: NOT_YET_RECRUITING
Conditions: Pain
Interventions: OTHER: Gentle Human Touch (GHT)|OTHER: Kangaroo Care|OTHER: Lactation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Aspirin Treatment for Small Unruptured InTracranial Aneurysms With Ischemic cereBrovascuLar diseasE
Status: NOT_YET_RECRUITING
Conditions: Intracranial Aneurysm|Cerebrovascular Disease
Interventions: DRUG: Aspirin Enteric-coated Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Neoplasms
Interventions: DRUG: Durvalumab|DRUG: Capivasertib|DRUG: Oleclumab|DRUG: Paclitaxel|DRUG: Trastuzumab deruxtecan|DRUG: Datopotamab deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: CXA-10|DRUG: pravastatin|DRUG: Vytorin® (combination of simvastatin and ezetimibe)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Timing of Endoscopy in Cirrhotic Patients With Acute Variceal Bleeding
Status: NOT_YET_RECRUITING
Conditions: Acute Upper Gastrointestinal Bleeding|Acute Variceal Bleeding
Interventions: PROCEDURE: Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Blood Pressure Treatment Thresholds Postpartum
Status: RECRUITING
Conditions: Hypertensive Disorder of Pregnancy|Pre-Eclampsia|Hypertension|Eclampsia|Gestational Hypertension|Cardiovascular Diseases|Toxemia|Pregnancy Complications|Vascular Diseases|Hypertension, Pregnancy Induced|Hypertension;Pre-Eclamptic
Interventions: DRUG: Usual care|DRUG: Tight blood pressure control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis
Status: RECRUITING
Conditions: Chronic Pain|Chronic Pain Syndrome|Chronic Pancreatitis|Hyperalgesia|Opioid Use Disorder|Opioid-Related Disorders|Opioid Dependence|Chronic Abdominal Pain|ERCP|Pancreatic Surgery
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During First Trimester Abortion
Status: COMPLETED
Conditions: Abortion in First Trimester
Interventions: DEVICE: Transcutaneous electrical nerve stimulation (TENS)|DRUG: Moderate IV Sedation|OTHER: SHAM: Transcutaneous electrical nerve stimulation (TENS)|OTHER: SHAM: Moderate IV Sedation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study in Different Sutures Techniques in Reduction of Known Abdominoplasty Complications and Improving Patients' Post-operative Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Abdominoplasty
Interventions: PROCEDURE: Running subcutaneous sutures technique|PROCEDURE: Classical closures
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Oxytocin in the Treatment of Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Options on the Breast Reconstruction Timing and Method After Removal of Polyacrylamide Hydrogel
Status: UNKNOWN
Conditions: Breast|Mammaplasty|Breast Reconstruction
Interventions: PROCEDURE: Immediate breast reconstruction with implant|PROCEDURE: delayed breast reconstruction with implant|PROCEDURE: delayed breast reconstruction with autologous fat transplantation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Web-based Tailored Health Behavior Intervention for Breast and Colon Cancer Survivors (eWellness)
Status: COMPLETED
Conditions: Nutrition|Physical Activity
Interventions: BEHAVIORAL: Intervention Physical Activity|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Dimolegin in Prevention of Thromboembolic Complications During Knee Replacement
Status: UNKNOWN
Conditions: Venous Thromboembolism
Interventions: DRUG: Dimolegin 40 mg|DRUG: Dimolegin 60 mg|DRUG: Fragmin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Hematopoietic Stem Cell Govern Residual Inflammatory Cardiovascular Risk in Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: DRUG: Semaglutide, 2.0 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Dulaglutide|DRUG: Aspart insulin|DRUG: Glargine|DRUG: Metformin|DRUG: Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene Mutation
Status: COMPLETED
Conditions: Uterine Cancer
Interventions: DRUG: Letrozole|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Tolerability of ABBV-467 in Adult Participants With Relapsed/Refractory (R/R) Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma (MM)|Cancer
Interventions: DRUG: ABBV-467
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Probiotic-based Product on Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: Fermented blueberry drink|OTHER: Placebo drink|OTHER: Sachets with probiotic bacterial powder|OTHER: Sachets with placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Study the COVAC-2 Booster Dose (for COVID-19) in Generally Healthy Adults.
Status: COMPLETED
Conditions: Double Vaccinated for COVID-19 (For Phase 1 of the Study)|Acute Respiratory Syndrome Coronavirus 2 (For Phase 2 Exploratory Group)
Interventions: BIOLOGICAL: COVAC-2|BIOLOGICAL: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine Followed by Clofarabine, Idarubicin, and Cytarabine in Acute Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Decitabine|DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Clofarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of 25 and 50 mg Doses of Proellex® in Treating the Recurrence of Uterine Fibroid Symptoms
Status: WITHDRAWN
Conditions: Uterine Fibroids
Interventions: DRUG: Proellex|DRUG: Proellex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Modafinil on Affective and Cognitive Processing
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Modafinil Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)
Status: TERMINATED
Conditions: Diabetic Foot Ulcer|Venous Leg Ulcer
Interventions: DEVICE: Synthetic Hybrid-Scale Fiber Matrix|DEVICE: Standard of Care|DEVICE: Living Cellular Skin Substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explore the Effectors of The Transtheoretical Model on Nutritional Education in Patients on Hemodialysis
Status: COMPLETED
Conditions: End-Stage Kidney Disease|Hyperphosphatemia
Interventions: BEHAVIORAL: multimedia education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Switching From Twice-Daily to Once-Daily Clozapine Dosing in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Clozapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Navtemadlin (KRT-232) With or Without Anti-PD-1/Anti-PD-L1 for the Treatment of Patients With Merkel Cell Carcinoma
Status: RECRUITING
Conditions: Merkel Cell Carcinoma
Interventions: DRUG: KRT-232|DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surgery and Photodynamic Therapy in Treating Patients With Malignant Mesothelioma
Status: COMPLETED
Conditions: Malignant Mesothelioma
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|DRUG: porfimer sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of hzVSf-v13 in Healthy Adults (Intravenous and Subcutaneous Administration)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: hzVSF-v13 (intravenous, single dose)|DRUG: hzVSF-v13 (subcutaneous, single dose)|DRUG: hzVSF-v13 (intravenous, multiple dose)|DRUG: Placebo (intravenous, single dose)|DRUG: Placebo (subcutaneous, single dose)|DRUG: Placebo (intravenous, multiple dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BASIC: Boosted Atazanavir or Saquinavir Induced Lipid Changes
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: saquinavir/ritonavir|DRUG: atazanavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DRUG: Dutasteride Capsules|DRUG: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fruquintinib Plus Camrelizumab and Capecitabine as Salvage Therapy After Progression on FOLFOXIRI-based First-line Treatment in Patients With Unresectable/Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Unresectable/Metastatic Colorectal Cancer
Interventions: DRUG: Fruquintinib plus camrelizumab and capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cannabinoids for Taxane Induced Peripheral Neuropathy
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: DRUG: Cannabinoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risperidone and Divalproex Sodium With MRI Assessment in Pediatric Bipolar
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Divalproex Sodium|DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Biological Therapy With or Without Bone Marrow or Peripheral Stem Cell Transplant in Treating Patients With Chronic Myelogenous Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: busulfan|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: hydroxyurea|DRUG: idarubicin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Epidural, Combined and Dural Puncture Labor Epidural on Pain, and Course of Vaginal Delivery
Status: UNKNOWN
Conditions: Labor Pain|Analgesia
Interventions: PROCEDURE: regional analgesia for labor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Treatment Intensification With Maraviroc on HIV-1 Viral Latency in Recently Infected Hiv-1 naïve Patients Starting Raltegravir Plus Tenofovir/Emtricitabine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Maraviroc|DRUG: Tenofovir/Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China
Status: RECRUITING
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Vericiguat (Verquvo, BAY1021189)|DRUG: Standard of Care (SoC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Compare Different Formulations of AZD3355
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AZD3355
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Antiviral Activity of TPV in HCV and/or HBV HIV Coinfected Patients TDM Randomised Pilot Evaluation
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: tipranavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Phospholipid and Sphingolipid Composition of High-density Lipoproteins (HDL) in Obese Non-diabetic Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Outcomes of Diabetic Macula Edema Patients Switched to Aflibercept From Bevacizumab and/or Ranibizumab
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreal Injection of Aflibercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intensive Versus Standard Blood Pressure Lowering to Prevent Functional Decline in Older People
Status: COMPLETED
Conditions: Hypertension, Systolic|Cerebrovascular Disease
Interventions: OTHER: Anti-hypertensive therapy to SBP 130 mm Hg|OTHER: Anti-hypertensive therapy to SBP 145 mm Hg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise at Workplace for Manual Material Handling Workers
Status: UNKNOWN
Conditions: Ergonomics|Manual Material Handling|Occupational Health
Interventions: OTHER: Exercise at workplace - Three times per week|OTHER: Exercise at workplace - Four times per week
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Evaluation of an Continuous Contactless Vitals Parameter Monitoring System Dozee VS
Status: COMPLETED
Conditions: No Specific Medical Conditions or Disease States
Interventions: DEVICE: Telemetry monitoring|DEVICE: Continuous monitoring through Earlysense|DEVICE: Continuous monitoring through Dozee VS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immune Responses in Prostate, Lung, Melanoma and Breast Cancer Patients Following Stereotactic Body Radiotherapy (SBRT), Intensity Modulated Radiotherapy (IMRT) or Brachytherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Breast Cancer|Lung Cancer|Melanoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: New Setting of Neurally Adjusted Ventilatory Assist During Mask Noninvasive Ventilation
Status: COMPLETED
Conditions: Acute Respiratory Failure|Mechanical Ventilation Complication
Interventions: OTHER: PSP|OTHER: NAVA|OTHER: PSN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of an Investigational Multi-Purpose Disinfecting Solution for the Care of Silicone Hydrogel Soft Contact Lenses
Status: COMPLETED
Conditions: Contact Lens Care
Interventions: DEVICE: OptiFree Multi-Purpose Disinfecting Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation and Dose Expansion Clinical Study of STI-7349 in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: STI-7349|DRUG: Pembrolizumab|DRUG: Standard treatment（SoC）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Acute Effects of a Knee-hip Powered Soft Exoskeleton in Patients With Neuromuscular Disorders
Status: RECRUITING
Conditions: Muscular Dystrophies|Congenital Myopathy|Idiopathic Inflammatory Myopathies|Mitochondrial Myopathies|Glycogen Storage Disease
Interventions: DEVICE: Knee-hip Powered Soft Exoskeleton (MyoSuit, MyoSwiss, Zurich, Switzerland)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: adalimumab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of Granexin® Gel to Improve Burn Wound Healing
Status: WITHDRAWN
Conditions: Second Degree Burn|Thermal Burn
Interventions: DRUG: Granexin® gel (200 μM)|DRUG: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of New Software Used During Ablations
Status: COMPLETED
Conditions: Liver Cancer|Neoplasms, Liver|Hepatic Neoplasms|Hepatic Cancer
Interventions: PROCEDURE: CT/CBCT thermometry method|PROCEDURE: Ablation Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto
Status: RECRUITING
Conditions: Urothelial Carcinoma|Urothelial Carcinoma Recurrent|Urothelial Carcinoma Ureter|Urothelial Carcinoma Ureter Recurrent|Urothelial Cancer of Renal Pelvis|Urothelial Carcinoma of the Renal Pelvis and Ureter|Carcinoma, Transitional Cell|Transitional Cell Carcinoma of Renal Pelvis
Interventions: DRUG: Jelmyto (mitomycin) for pyelocalyceal solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluate Safety, Whole-Body Distribution and Radiation Dosimetry in Metastatic Castration Resistant Prostate Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: ZA-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Higher Dose of Ramipril Versus Addition of Telmisartan-Ramipril in Hypertension and Diabetes
Status: TERMINATED
Conditions: Hypertension|Type 2 Diabetes|Albuminuria
Interventions: DRUG: ramipril|DRUG: ramipril-telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Interventions for Active Duty Service Members and Veterans With Chronic Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Mindfulness-Oriented Recovery Enhancement (MORE)|BEHAVIORAL: Support Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Framingham Heart Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases|Coronary Disease|Cerebrovascular Accident|Hypertension|Heart Failure, Congestive|Peripheral Vascular Diseases|Arterial Occlusive Diseases|Atherosclerosis|Heart Failure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Inpatient Monitoring of Unfractionated Heparin
Status: ENROLLING_BY_INVITATION
Conditions: Blood Clot|Thrombosis
Interventions: OTHER: PTT protocol|OTHER: anti-Xa protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks
Status: COMPLETED
Conditions: Metabolic Syndrome|Insulin Resistance|Dyslipidemia
Interventions: OTHER: Glucose|OTHER: Fructose|OTHER: High-Fructose Corn Syrup|OTHER: No sugar (Aspartame)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.
Status: WITHDRAWN
Conditions: Hypertension|Diabetes Mellitus, Type 2
Interventions: DRUG: Ertugliflozin|DRUG: Hydrochlorothiazide 12.5mg|DEVICE: Microneurography|OTHER: SKNA recordings|OTHER: Static Handgrip|OTHER: Post-handgrip forearm vascular occlusion|OTHER: Testing of the Arterial Baroreflex Function
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/ Phase 2 Study of TTHX1114(NM141)
Status: COMPLETED
Conditions: Corneal Endothelial Dystrophy|Fuchs Endothelial Corneal Dystrophy|Pseudophakic Bullous Keratopathy|Endothelial Dysfunction
Interventions: DRUG: TTHX1114(NM141)|OTHER: Vehicle (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
Status: COMPLETED
Conditions: Down Syndrome
Interventions: OTHER: Skeletal Status Assessment of a Down Syndrome Population
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg
Status: NOT_YET_RECRUITING
Conditions: Allergy
Interventions: DRUG: cetirizine HCl Gummy|DRUG: Zyrtec tablet 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Selective Serotonin Reuptake Inhibitor (SSRI) in Overactive Bladder Patients
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Selective serotonin reuptake inhibitors|DRUG: Antimuscarinics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infection
Interventions: DRUG: Presatovir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Co-administration of Thiamine Pyrophosphate and Metformin in Type 2 Diabetes
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DIETARY_SUPPLEMENT: Thiamine pyrophosphate|OTHER: Placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Personalizing Cognitive Remediation for Schizophrenia by Targeting Impairments in Early Auditory Processing
Status: ENROLLING_BY_INVITATION
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Brain Basics|BEHAVIORAL: Brain Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tegoprazan or RAPA114 on Pharmacokinetic of Atorvastatin in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Atorvastatin 40 mg|DRUG: Tegoprazan 50 mg|DRUG: RAPA114
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of Two Tobacco Cessation Interventions for Employees of Partners HealthCare, Inc.
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Use Disorder
Interventions: BEHAVIORAL: Internal tobacco coach|BEHAVIORAL: External tobacco coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Real-world Study of Obinutuzumab-based Therapy for Previously Untreated FL
Status: RECRUITING
Conditions: Follicular Lymphoma
Interventions: DRUG: Obinutuzumab|DRUG: Lenalidomide|DRUG: Bendamustine|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ELR Monitoring Against Permanent Pacemaker in Atrial Fibrillation
Status: UNKNOWN
Conditions: Atrial Fibrillation
Interventions: DEVICE: R test|DEVICE: Nuubo|DEVICE: TECHNOMED pocket ECG|DEVICE: ZIO xt patch|DEVICE: MoMe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell|PKLR Variants|Adenosine Triphosphate Activities
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.
Status: COMPLETED
Conditions: Hypertrophic Obstructive Cardiomyopathy
Interventions: PROCEDURE: myoectomy|PROCEDURE: Mitral valve surgery|PROCEDURE: Mitral valve surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Development of Postnatal Mobile Support Application
Status: COMPLETED
Conditions: Postpartum Depression|Postnatal Complication|Nurse's Role
Interventions: DEVICE: Postpartum Mobile Support Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE