pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cryotherapy as a Coadjuvant in Crotaline Snakebite Management With Antivenom.
Status: COMPLETED
Conditions: Snake Bites
Interventions: BIOLOGICAL: F(ab)2 antivenom therapy (antivipmyn®).|PROCEDURE: Local cryotherapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1839100|DRUG: Placebo matching BI 1839100|DRUG: midazolam|DRUG: digoxin|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparative Hybrid Effects of Combining BoNT-A With Robot-assisted or Mirror Therapy for U/E Spasticity Stroke Patients
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: Botulinum Toxin Type A|OTHER: Robot-assisted therapy|OTHER: Mirror therapy|OTHER: Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Multiple Micronutrient Supplementation (MMS) in Indonesia
Status: RECRUITING
Conditions: Nutrient Deficiency
Interventions: BEHAVIORAL: MMS (90x2) + BCC or expanded BCC|BEHAVIORAL: MMS (180x1) + BCC or expanded BCC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: INTELLiVENT-ASV Using Mainstream Versus Sidestream End-Tidal CO2 Monitoring
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Intensive Care Unit|Postoperative Care
Interventions: DEVICE: Sidestream capnography using the 'Respironics LoFlo Sidestream CO2 Module'|DEVICE: Mainstream capnography using the 'Respironics Capnostat 5 Mainstream CO2 sensor'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of New Intermittent Catheter Swelling Media in Healthy Volunteers
Status: COMPLETED
Conditions: Catheter Site Pain|Catheter Site Discomfort
Interventions: DEVICE: Novel swelling media|DEVICE: Comparator swelling media
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial.
Status: RECRUITING
Conditions: Clinical Complete Response Rate With Negative MRD
Interventions: DRUG: Tireilizumab（PD-1 inhibitor）
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The WalkOut Study
Status: COMPLETED
Conditions: Osteoarthritis|Pain|Arthritis|Gonarthritis|Sedentary|Knee Osteoarthritis|Motor Activity|Physical Activity
Interventions: OTHER: Walking|OTHER: Department of Health Physical Activity Guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CLINICAL EVALUATION OF THE EFFICACY OF AN INTRA ORAL SPRAY FOR PATIENTS WITH XEROSTOMIA
Status: COMPLETED
Conditions: Dry Mouth, Xerostomia.Hyaluronic Acid, Xylitol
Interventions: DEVICE: Lubricity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mobile Phone Support for Adults and Support Persons to Live Well With Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: FAMS 2.0|BEHAVIORAL: Print Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Marginal Integrity of Hydroxyapatite Nano-Fiber Reinforced Flowable Composite Versus Conventional Resin-Based Flowable Composite in Initially Demineralized Pits and Fissure: A One Year, Randomized Clinical Trial
Status: UNKNOWN
Conditions: Marginal Integrity of Hydroxyapatite Nanofiber Reinforced Flowable Composite
Interventions: OTHER: Conventional resin-based flowable composite|OTHER: Hydroxyapatite Nanofiber reinforced flowable composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and PK of Oral Encochleated Amphotericin B (CAMB/MAT2203) for Antifungal Prophylaxis in Patients Undergoing Induction Chemotherapy for Acute Myelogenous and Lymphoblastic Leukaemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Oral Encochleated Amphotericin B (CAMB)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PD-1 Antibody, Chidamide, Lenalidomide and Gemcitabine for Peripheral T-cell Lymphoma
Status: UNKNOWN
Conditions: Peripheral T-cell Lymphoma
Interventions: DRUG: PD-1 blocking antibody, chidamide, lenalidomide and gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-based Cognitive Behavior Therapy After Myocardial Infarction
Status: COMPLETED
Conditions: Depression|Anxiety|Myocardial Infarction
Interventions: BEHAVIORAL: Internet-based CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Different Bending Mode for Double-lumen Endotracheal Tube Intubation
Status: COMPLETED
Conditions: Anesthesia Intubation Complications
Interventions: PROCEDURE: the DLT bending to the right|PROCEDURE: the DLT bending to the left
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COMPARISON OF NITROFURANTOIN WITH FOSFOMYCIN in TREATING CYSTITIS IN WOMEN
Status: NOT_YET_RECRUITING
Conditions: Urinary Tract Infections
Interventions: DRUG: Nitrofurantoin 100 MG|DRUG: Fosfomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of DCVAC/PCa Added to Hormone Therapy for Men With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Dendritic Cells DCVAC/PCa|DRUG: Leuprolide acetate|DRUG: Goserelin Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study for Efficacy and Safety Assessment of the Drug RADAMIN®VIRO for COVID-19 Postexposure Prophylaxis
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Double-Stranded RNA sodium salt|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation on the Cortical Communication System
Status: RECRUITING
Conditions: Locked-in Syndrome|Neuromuscular Diseases|Brainstem Stroke|Traumatic Brain Injury
Interventions: DEVICE: ECoG (electrocorticography) sensing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease
Status: RECRUITING
Conditions: Autosomal Dominant Polycystic Kidney Disease|ADPKD|Polycystic Kidney, Autosomal Dominant
Interventions: DRUG: RGLS8429|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Neoadjuvant Metronomic Chemotherapy in Triple-Negative Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Doxorubicin / Cyclophosphamide / Paclitaxel / Carboplatin|PROCEDURE: Definitive Surgery|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Velpatasvir in Participants With Chronic HCV Infection
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus
Interventions: DRUG: Velpatasvir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Study of Postoperative Adjuvant Therapy of Uracil-tegafur (UFT) Compared With Cyclophosphamide/Methotrexate/5-fluorouracil (CMF) in Breast Cancer (NSAS-BC)
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: UFT (uracil, tegafur)|DRUG: cyclophosphamide, methotrexate, and fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab for Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Exudative Age-related Macular Degeneration
Interventions: DRUG: Bevacizumab 1|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Suvorexant in Treatment of Patients With Substance Use Disorder and Insomnia: A Pilot Open Trial
Status: COMPLETED
Conditions: Sleep Disturbance|Craving|Cortisol; Hypersecretion
Interventions: DRUG: Suvorexant 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Exercise And Colorectal Cancer Treatment Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Colon Cancer|Rectal Cancer
Interventions: BEHAVIORAL: Moderate-Intensity Aerobic Exercise|BEHAVIORAL: Wait-List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of SystemCHANGE to Improve Exercise, Diet and Health in HIV-Infected Adults
Status: COMPLETED
Conditions: HIV|Cardiovascular Disease
Interventions: BEHAVIORAL: SystemCHANGE|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab Plus Gemcitabine in Treating Patients With Locally Advanced, Metastatic, or Recurrent Cancer of the Pancreas
Status: WITHDRAWN
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer
Status: UNKNOWN
Conditions: Colonic Neoplasms
Interventions: PROCEDURE: Therapeutic conventional colorectal surgery|PROCEDURE: Therapeutic laparoscopic colorectal surgery|OTHER: Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IV Paracetamol, Dexketoprofen or Morphine for the Treatment of Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: paracetamol|DRUG: morphine|DRUG: Dexketoprofen|DRUG: Paracetamole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Protein Content of Formulas on Nutrition Status of Infants.
Status: COMPLETED
Conditions: Growth & Development|Formula Feeding of Healthy Full Term Infants|Breast Feeding of Healthy Full Term Infants
Interventions: OTHER: Infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Adipose Tissue Function and Response to Exercise Training in Women With and Without Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: BEHAVIORAL: 4x4 minutes high intensity interval training|BEHAVIORAL: 10x1 minute high intensity interval training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Postural Control Through Innovative Stimulation of the Proprioceptive System
Status: COMPLETED
Conditions: Sensorimotor Disorder
Interventions: OTHER: POSTUR|OTHER: Localised Vibration|OTHER: Somatosensory Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prostate Cancer Prevention Study for Men With High Grade PIN (Prostatic Intraepithelial Neoplasia)
Status: COMPLETED
Conditions: Preneoplastic Conditions|Prostatic Intraepithelial Neoplasia
Interventions: DRUG: Toremifene 20 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Different Strategy of Fluids Administration on Acid/Base Disorders and Inflammatory Mediators
Status: COMPLETED
Conditions: Large Bowel Cancer
Interventions: BEHAVIORAL: balanced solutions|BEHAVIORAL: not balanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation
Status: RECRUITING
Conditions: Bone Loss in Jaw
Interventions: DEVICE: DFDBA fibers|DEVICE: DFDBA particles|DEVICE: DBBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single Bolus of Dexmedetomidine Versus Nalbuphine in Postoperative Agitation
Status: RECRUITING
Conditions: Cleft Palate
Interventions: DRUG: Dexmedetomidine|DRUG: Nalbuphine|OTHER: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of ION547
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ION547|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of One-week on/One-week Off Temozolomide Versus Continuous Dose-Intense Temozolomide in Patients With Glioblastoma Multiforme at First Relapse
Status: COMPLETED
Conditions: Glioblastoma
Interventions: DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pembrolizumab for Refractory Atypical and Anaplastic Meningioma
Status: UNKNOWN
Conditions: Atypical Meningioma|Anaplastic Meningioma|Hemangiopericytoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Bias Modification for Transdiagnostic Anxiety
Status: COMPLETED
Conditions: Anxiety|Anxiety Disorders
Interventions: BEHAVIORAL: Attention Bias Modification|BEHAVIORAL: Neutral Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Home INR Study
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Weekly patient self-testing of prothrombin time|OTHER: High quality anticoagulation management (HQACM) with conventional monthly testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile SMART Exercise Support Program to Improve Fatigue in Lung Cancer Patients - A RCT
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Brief mobile SMART Exercise Support Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC
Status: RECRUITING
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: OTHER: Patient-specific adaptive therapy|DRUG: Abiraterone acetate|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety & Efficacy Clinical Study to Evaluate the Narrowing of the Renal Arteries While Using Gadodiamide
Status: COMPLETED
Conditions: Renal Artery Stenosis
Interventions: DRUG: Gadodiamide Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study With L19TNF in Combination With Lomustine in Patients With Glioblastoma at Progression or Recurrence
Status: NOT_YET_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: L19TNF|DRUG: L19TNF|DRUG: L19TNF|DRUG: Lomustine|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VI-0521 Compared to Placebo in the Glycemic Management of Obese Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: VI-0521|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Micronized dHACM Injectable for the Treatment of Plantar Fasciitis
Status: COMPLETED
Conditions: Fasciitis, Plantar
Interventions: OTHER: AmnioFix® Injectable|DRUG: Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin
Status: NOT_YET_RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: 14-day bismuth quadruple regimen containing cefuroxime and tetracycline|DRUG: 14-day bismuth quadruple regimen containing cefuroxime and levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Pembrolizumab+Carboplatin in Breast Related Cancer Antigens-related Metastatic Breast Cancer (PEMBRACA)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pembrolizumab 25 MG(milligram)/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/Expansion Study of Dasatinib
Status: TERMINATED
Conditions: Refractory Solid Tumors|Pancreatic Adenocarcinoma
Interventions: DRUG: gemcitabine|DRUG: dasatinib|DRUG: gemcitabine|DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Physical Activity Self-Management Intervention for Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Physical activity self-management|OTHER: COPD education + Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Multicenter Study in Postmenopausal Women With Osteoporosis, ALVOBOND
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoporosis, Postmenopausal
Interventions: BIOLOGICAL: AVT03|BIOLOGICAL: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD)
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Empagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a 12-week Combined Exercise Program on Ghrelins in Obese Adolescent Girls
Status: COMPLETED
Conditions: Ghrelin
Interventions: OTHER: Combined exercise program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Melphalan, Yttrium Y 90 Ibritumomab Tiuxetan, and Rituximab Followed by Autologous Stem Cell Transplant in Treating Older Patients With Non-Hodgkin's Lymphoma That Has Relapsed or Not Responded to Previous Treatment
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: ibritumomab tiuxetan|DRUG: rituximab|DRUG: melphalan|DRUG: vinorelbine tartrate / G-CSF|PROCEDURE: autologous hematopoietic stem cell harvesting and transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of MRI AI-cTB Versus Routine cTB in Prostate Cancer Diagnosis: a Prospective Randomized Controlled Trial
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: MRI-AI guided cognitive prostate targeted biopsy|PROCEDURE: Routine cognitive prostate targeted biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Balance Rehabilitation With Sensory Recalibration After Stroke
Status: COMPLETED
Conditions: Left-sided Hemiplegia Affecting Dominant Side as Late Effect of Cerebrovascular Accident
Interventions: OTHER: Cervical vibration|OTHER: Prism adaptation|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia; Psychosis|Nurse's Role|Delusions
Interventions: BEHAVIORAL: cognitive defusion techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Doxorubicin, Cisplatin, 5-Fluorouracil in Patients With Advanced Adenocarcinoma of the Stomach or Esophagus
Status: COMPLETED
Conditions: Adenocarcinoma of Stomach|Adenocarcinoma of GE Junction|Adenocarcinoma of Esophagus
Interventions: DRUG: Doxorubicin|DRUG: Cisplatin|DRUG: 5-fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ONCOS-102 in Combination With Other Novel Immune-therapies in Advanced Treatment-resistant Melanoma Patients
Status: WITHDRAWN
Conditions: Melanoma
Interventions: BIOLOGICAL: ONCOS-102|BIOLOGICAL: Balstilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Varied Outreach Methods on Appointment Scheduling and Appointment Completion Using MyChart
Status: COMPLETED
Conditions: Health Care Utilization
Interventions: OTHER: No Message|OTHER: Standard message|OTHER: Tailored message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease
Status: RECRUITING
Conditions: End Stage Renal Disease on Dialysis
Interventions: DRUG: Empagliflozin 25 mg vs Placebo|DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Exercise in Improving Mobility and Reducing Fatigue and/or Weakness in Older Cancer Survivors
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Colorectal Cancer|Esophageal Cancer|Fatigue|Lung Cancer|Lymphoma|Ovarian Cancer|Prostate Cancer
Interventions: BEHAVIORAL: exercise intervention|PROCEDURE: complementary or alternative medicine procedure|PROCEDURE: fatigue assessment and management|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerability and Immunogenicity Study of AV7909 Anthrax Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Bacillus Anthracis (Anthrax) Infection
Interventions: BIOLOGICAL: BioThrax|BIOLOGICAL: AV7909 Formulation 1|BIOLOGICAL: AV7909 Formulation 2|BIOLOGICAL: AV7909 Formulation 3|BIOLOGICAL: AV7909 Formulation 4|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Magnetocardiography in Evaluation of Patients Going for Cardiac Catheterization
Status: TERMINATED
Conditions: Acute Coronary Syndrome|Coronary Artery Stenosis|Myocardial Ischemia
Interventions: DIAGNOSTIC_TEST: CardioFlux Magnetocardiograph
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of NT 201 (Botulinum Neurotoxin Type A Free of Complexing Proteins) on Sleep-related Breathing Disorders
Status: WITHDRAWN
Conditions: Sleep-Disordered Breathing
Interventions: DRUG: NT 201, a Botulinum neurotoxin type A, free of complexing proteins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cytomegalovirus (CMV) Vaccines: Reinfection and Antigenic Variation
Status: RECRUITING
Conditions: Cmv Congenital|CMV Viremia
Interventions: DIAGNOSTIC_TEST: Women Enrolled|DIAGNOSTIC_TEST: Newborns of Female Study Participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Renal Anhydramnios Fetal Therapy
Status: RECRUITING
Conditions: Anhydramnios|Potter Syndrome|Lung Hypoplasia|Multicystic Dysplastic Kidney|Multicystic Renal Dysplasia, Bilateral|Lower Urinary Tract Obstructive Syndrome|Fetal Renal Anomaly
Interventions: PROCEDURE: Serial amnioinfusions with isotonic fluid|DEVICE: Spinal needle|DRUG: Isotonic fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder
Status: COMPLETED
Conditions: Insomnia Disorder
Interventions: DRUG: Daridorexant 25 mg|DRUG: Daridorexant 50 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Reduced Dose Enzalutamide in Frail (m)CRPC Patients on Cognitive Side Effects
Status: COMPLETED
Conditions: Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2216684 in Healthy Participants
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2216684|DRUG: Placebo-matching LY2216684|DRUG: Placebo-matching alcoholic beverage|DRUG: Alcoholic beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAPESTRY With Health Connnectors for Diabetes Management
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Hypertension
Interventions: BEHAVIORAL: TAP-HC-DM|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Clinical Evaluation of the Durata or Optisure High Voltage Leads and Ellipse VR ICD Undergoing MRI, an IDE Study
Status: COMPLETED
Conditions: Implantable Defibrillator User
Interventions: DEVICE: Ellipse VR ICD and Durata/Optisure lead
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Physical Programs on the Body Composition of Adult Men and Women With an Initial Body Fat >25% and >30%, Respectively.
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: education and modifying diet|BEHAVIORAL: education, modifying diet and physical activity prescription
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Phase 1 Oral Solution and Crushed Tablet Relative Bioavailability Study of Apixaban When Administered Through a Nasogastric Tube in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Apixaban|DIETARY_SUPPLEMENT: Boost Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of the WHO Recommended Vitamin A Supplementation at Immunisation Contacts
Status: TERMINATED
Conditions: Mortality|Morbidity
Interventions: BIOLOGICAL: Vitamin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 1-2 Study of PRT-201 Administered in Chronic Kidney Disease (CKD) Patients
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: PRT-201|DRUG: PRT-201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Breaking up Sedentary Time to Improve Glucose Control in a Population at Risk for Developing Type 2 Diabetes
Status: RECRUITING
Conditions: Pre-diabetes
Interventions: BEHAVIORAL: BREAK|BEHAVIORAL: ONE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of L-arginine Supplementation on Anaerobic Exercise Performance
Status: RECRUITING
Conditions: Skeletal Muscle|Human Performance
Interventions: DIETARY_SUPPLEMENT: L-arginine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ultrasound-Guided Versus Conventional Injection for Caudal Block
Status: COMPLETED
Conditions: Ultrasound Therapy; Complications
Interventions: DRUG: Levobupivacaine|DRUG: Morphine Sulfate|DEVICE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Glyburide/Metformin 5 mg/500 mg Tablets|DRUG: Glucovance® 5 mg/500 mg Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing Daily Mindfulness Interventions Using Peer Support to Increase Well-Being in First-Year Students
Status: UNKNOWN
Conditions: OMI, OMI+, Control Group
Interventions: BEHAVIORAL: Benign Behavioral Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Efficacy Of 4% ArtpharmaDent Versus 2% Mepecaine-L in Extraction of Lower First Primary Molars
Status: UNKNOWN
Conditions: Badly Decayed Lower First Primary Molars in Children
Interventions: DRUG: articaine|DRUG: Mepivacaine 2% Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy, Pharmacodynamics, Safety, and Immunogenicity Between Bmab 1000 and Prolia® in Postmenopausal Women With Osteoporosis
Status: COMPLETED
Conditions: Postmenopausal Women With Osteoporosis
Interventions: BIOLOGICAL: Bmab 1000|BIOLOGICAL: Prolia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Idarubicin and Cytarabine for the Treatment of Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia|AML
Interventions: DRUG: Cytarabine|DRUG: Idarubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paced Heart Rate Acceleration for Cardiac Conditioning
Status: RECRUITING
Conditions: Heart Failure, Systolic
Interventions: DEVICE: Exercise-similar cardiac pacing|DEVICE: Sham cardiac pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypoxic Exercise and Glucose Metabolism
Status: COMPLETED
Conditions: Obesity|Insulin Resistance|Impaired Glucose Tolerance in Obese
Interventions: OTHER: Moderate intensity exercise under mild normobaric hypoxia and normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors
Status: WITHDRAWN
Conditions: Cancer
Interventions: DRUG: paclitaxel albumin-stabilized nanoparticle formulation|PROCEDURE: gene expression analysis|PROCEDURE: laboratory biomarker analysis|PROCEDURE: pharmacological study|PROCEDURE: polymerase chain reaction
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study of Duloxetine in Fibromyalgia (Extension of F1J-JE-HMGZ, NCT01552057)
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sinus Floor Elevation Using Alpha-Bio's GRAFT Natural Bovine Bone vs. Commercially Available Bone Graft
Status: UNKNOWN
Conditions: Sinus Floor Augmentation
Interventions: DEVICE: Alpha-Bio GRAFT Natural Bovine Bone|DEVICE: natural bone substitute
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study Investigating Human Skin Reaction to Output
Status: COMPLETED
Conditions: Ileostomy
Interventions: OTHER: Patch 1|OTHER: Patch 2|OTHER: Patch 3|OTHER: Patch 4|OTHER: Patch 5|OTHER: Patch 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate Arikace™ in CF Patients With Chronic Infection Due to Pseudomonas Aeruginosa
Status: WITHDRAWN
Conditions: Cystic Fibrosis
Interventions: DRUG: Liposomal amikacin for inhalation|DRUG: Placebo for liposomal amikacin for inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Treatment Using the MyoRegulator® Device in Patients With Spasticity in the Lower Limb Due to Stroke
Status: COMPLETED
Conditions: Muscle Spasticity|Stroke
Interventions: DEVICE: MyoRegulator®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-Cell Depletion in Unrelated Donor Marrow Transplantation
Status: COMPLETED
Conditions: Bone Marrow Transplantation|Graft vs Host Disease|Immunologic Diseases|Leukemia|Myelodysplastic Syndromes
Interventions: PROCEDURE: lymphocyte depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta at Different Time Intervals During Controlled Ovarian Stimulation.
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: FE 999302|DRUG: Follitropin delta|DRUG: Placebo FE 999302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Usability of the ADEPTH Sensor for Bore Depth Measurements in Plate Osteosynthesis Procedures
Status: RECRUITING
Conditions: Fractures, Bone|Osteosynthesis
Interventions: DEVICE: ADEPTH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial to Evaluate the Efficacy of Fecal Microbiota Transplantation in Patients With Alopecia Areata
Status: WITHDRAWN
Conditions: Alopecia Areata|Alopecia Totalis|Alopecia Universalis
Interventions: DRUG: Fecal material transfer therapy|PROCEDURE: 4mm Punch Biopsy of Scalp|DIAGNOSTIC_TEST: Blood draw|PROCEDURE: Skin Microbiome sampling|PROCEDURE: Hair Microbiome Sampling|DRUG: Pre-FMT Antibiotic Cocktail|DRUG: Bowel Prep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study to Explore the Safety and Efficacy of the HDx Therapy Using Theranova 500 Dialyzer in Comparison to Hemodiafiltration
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Theranova 500 medium cut-off dialyzer|DEVICE: Hemodiafiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Bevacizumab and Extended Treatment of Temozolomide in Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: DRUG: bevacizumab [Avastin]|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Intensity, Dynamic-stability Gait Training in People With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: High-Intensity Treadmill Training|PROCEDURE: Treadmill Training with Perturbations|PROCEDURE: Standard Treadmill Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SYH2051 Monotherapy in Advanced Solid Tumors or in Combination With Radiotherapy in Locally Advanced Head and Neck Cancer
Status: RECRUITING
Conditions: Solid Tumors|Head and Neck Cancer
Interventions: DRUG: SYH2051 tablets|RADIATION: Intensity-Modulated Radiation Therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: niacin (+) laropiprant|DRUG: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-CD7 CAR-Engineered T Cells for T Lymphoid Malignancies Malignancies
Status: UNKNOWN
Conditions: T-Cell Lymphocytic Leukemia|T-Cell Chronic Lymphocytic Leukemia|T Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Fludarabine + Cyclophosphamide + CAR7-T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-Blind Study of Buprenorphine Treatment of Acute Suicidality
Status: UNKNOWN
Conditions: Depression|Suicidal Ideation|Suicidal Action
Interventions: DRUG: buprenorphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cretostimogene Given in Patients With Non-Muscle Invasive Bladder Cancer ,Unresponsive to Bacillus-Calmette-Guerin
Status: RECRUITING
Conditions: Non Muscle Invasive Bladder Cancer|High-grade Ta/ T1 Papillary Disease Bladder Cancer
Interventions: BIOLOGICAL: Cretostimogene Grenadenorepvec|OTHER: n-dodecyl-B-D-maltoside
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.
Status: COMPLETED
Conditions: COVID-19|Low Triiodothyronine Syndrome|Adrenal Insufficiency|Subacute Thyroiditis|Hypothyroidism|Hyperthyroidism
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study 1 Replication and Extension of Prior Work
Status: ACTIVE_NOT_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Overheard Speech|BEHAVIORAL: Addressed Speech
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: BEHAVIORAL: Structured Ecosystems Therapy (SET)|BEHAVIORAL: Individually tailored intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Investigate the Pharmacokinetics of Prolonged-release Melatonin Compared to Standard, Immediate-release Melatonin in Healthy Adults
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Prolonged-Release Melatonin|DIETARY_SUPPLEMENT: Immediate-Release Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature Infants
Status: COMPLETED
Conditions: Nosocomial Infections|Sepsis|Staphylococcal Infections|Candidemia
Interventions: DRUG: Veronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Effects of Desloratadine and Placebo in the Relief of Nasal Symptom Scores in Subjects With Seasonal Allergic Rhinitis to Cypress Pollen (Study P02836)
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Placebo|DRUG: Desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemo-radiotherapy With Intensity-Modulated Radiation Therapy (IMRT) for Limited Disease Small Cell Lung Cancer (LD-SCLC)
Status: COMPLETED
Conditions: Stage I-III Small Cell Lung Cancer
Interventions: RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Status: COMPLETED
Conditions: Symptomatic Irreversible Pulpitis
Interventions: PROCEDURE: GGNB injections|PROCEDURE: IANB injections|PROCEDURE: GGNB + IANB injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of ATH434 in Participants With Multiple System Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple System Atrophy
Interventions: DRUG: ATH434 dose level 1|DRUG: ATH434 dose level 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain
Status: COMPLETED
Conditions: Chronic Pain|Arthritis Hand|Opioid Use
Interventions: OTHER: Standard of care|DEVICE: Nottingham AR smartphone app with active intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT