pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Adjuvant Chemotherapy Trial of TS-1 for Gastric Cancer (ACTS-GC)
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: TS-1 (S-1)|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Introducing Mifepristone-Misoprostol for Menstrual Regulation in Public Sector Facilities in Bangladesh
Status: COMPLETED
Conditions: Menstrual Regulation
Interventions: DRUG: Mifepristone and misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: An Exploratory Randomized Controlled Study of Arthroscopic Inlay Bristow Procedure for Recurrent Anterior Shoulder Dislocation
Status: COMPLETED
Conditions: Shoulder Dislocation
Interventions: PROCEDURE: Inlay Bristow|PROCEDURE: Bristow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function.
Status: COMPLETED
Conditions: Advanced Urothelial Cancer|Metastatic Urothelial Cancer
Interventions: DRUG: Carboplatin|DRUG: Fractionated Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Consolidation After Radical Treatment of Synchronous Oligo-metastatic NSCLC
Status: NOT_YET_RECRUITING
Conditions: NSCLC Stage IV
Interventions: DRUG: Cemiplimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sepsis Post Market Observational Study and Potential Reduction of Time to Antibiotics - Baylor S&W
Status: COMPLETED
Conditions: Sepsis|Adult Disease|Emergency Department|Severe Sepsis
Interventions: DIAGNOSTIC_TEST: CBC-DIFF Monocyte Volume Width Distribution (MDW)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Effects of Cannabidiol for Simple Tooth Extractions in Dental Patients
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: cannabidiol|DRUG: placebo|DRUG: acetaminophen 500mg and ibuprofen 200mg combo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Prospective Evaluation of the Toad Brace in Plantar Ulcer Off-loading and Healing
Status: UNKNOWN
Conditions: Diabetic Foot|Pedal Ulcers
Interventions: DEVICE: Optimal Medical Therapy Debridement + Toad Brace|OTHER: Optimal Medical Therapy - Debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Local Anesthesia as a Method to Decrease IUD Insertion Related Pain
Status: WITHDRAWN
Conditions: IUD Insertion Complication|Pain Control
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validity of Patient-Collected Wet Mounts
Status: COMPLETED
Conditions: Vaginal Discharge|Trichomonas|Candidiasis|Vaginosis, Bacterial|Vaginitis
Interventions: OTHER: vaginal swab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Factors Associated With Adherence to Hygiene-related Behaviors and Viral Mitigation Protocols During the COVID-19 Pandemic
Status: UNKNOWN
Conditions: Adherence to WHO-advised Hygiene-related Behavior|Adherence to Viral Mitigation Protocols
Interventions: BEHAVIORAL: Prospective study with two measurement points investigating the impact of viral mitigation protocols on mental health
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Prospective, Randomised Controlled, Phase II Clinical Study of Tirilizumab in Combination With Albumin-bound Paclitaxel With Cisplatin for Neoadjuvant and Adjuvant Treatment of Locally Advanced Resectable Oral Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: tirilizumab with albumin-bound paclitaxel and cisplatin|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study Looking at the Use of a Natural Killer Cell Line Against Hematological Malignancies
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Myeloma|Hodgkin's Disease
Interventions: BIOLOGICAL: NK-92 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auditory Slow Wave Enhancement in Parkinson Disease and Mild Cognitive Impairment
Status: RECRUITING
Conditions: Parkinson Disease|Mild Cognitive Impairment
Interventions: DEVICE: TSB Axo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases
Status: RECRUITING
Conditions: Spine Metastases|Spine Stereotactic Radiosurgery (sSRS)
Interventions: DEVICE: Diagnostic MRI|DEVICE: Planning MRI|OTHER: Simulation CT|OTHER: QOL assessment|OTHER: Brief pain inventory (BPI)|RADIATION: sSRS in 1 fraction|RADIATION: sSRS in 2 fraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Manual Therapy and Pelvic Floor Exercises on Pelvic Floor Muscles
Status: RECRUITING
Conditions: Colonic Inertia|Dyschezia|Constipation
Interventions: OTHER: pelvic floor exercises|OTHER: Pelvic floor exercises and manual therapy techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes
Status: COMPLETED
Conditions: Hypertriglyceridemia (TG>200<500)|Hyperlipidemia|Coronary Artery Disease|Coronary Risk Equivalent|Diabetes
Interventions: DRUG: docosahexanoic acid (DHA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Benefits of Genicular Nerve Blocks of the Posterior Knee for Patients Undergoing ACL Reconstruction
Status: TERMINATED
Conditions: Rupture of Anterior Cruciate Ligament
Interventions: DRUG: Bupivacaine|DRUG: Preservative free normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Innovations Applied to the Pyrenean Beef Production to Enhance Consumer-identifiable Meat.
Status: COMPLETED
Conditions: Body Weight Changes|Habits, Diet|Habit, Food|Life Change Events
Interventions: OTHER: Pyrenees´ Beef diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Toripalimab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Neoplasms Immunotherapy
Interventions: DRUG: Toripalimab|DRUG: Lenvatinib|DRUG: Gemox Chemotherapy（Gemox or GC）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brain Integrity in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation
Status: COMPLETED
Conditions: Hodgkin Lymphoma
Interventions: OTHER: Neurocognitive Evaluation|OTHER: Quantitative Brain Imaging|OTHER: Neurologic Evaluation|OTHER: Health Questionnaire|OTHER: Vascular Testing|OTHER: Cardiopulmonary Exercise Testing|OTHER: Echocardiography|OTHER: Pulmonary Function Testing|PROCEDURE: Serum Biomarkers|OTHER: Ophthalmology Examination
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Empagliflozin as Adjuvant Therapy in Patients With Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Anesthesia For Enhanced Recovery After Liver Surgery
Status: RECRUITING
Conditions: Hepatectomy|Pain, Postoperative|Liver Neoplasms
Interventions: PROCEDURE: Continuous thoracic epidural analgesia|PROCEDURE: Spinal anesthesia with intrathecal morphine|DRUG: Bupivacaine 0.75% in Dextrose Inj 8.25%|DRUG: Morphine|DRUG: Bupivacaine 0.25% Preservative-Free Injectable Solution|DRUG: Bupicavaine 0.125% epidural solution|DRUG: Hydromorphone 10 mcg/mL epidural solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB
Status: COMPLETED
Conditions: Tuberculosis, Pulmonary
Interventions: DRUG: SQ109|DRUG: Rifampicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MONET1-MOtesanib NSCLC Efficacy and Tolerability Study
Status: TERMINATED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: AMG 706|DRUG: placebo|DRUG: paclitaxel|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Injectable Platelet-rich Fibrin in the Treatment of the Female Stress Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence|Treatment
Interventions: OTHER: Local applied injectable platelet-rich fibrin in women with stress urinary incontinence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VA NEPHRON-D: Diabetes iN Nephropathy Study
Status: TERMINATED
Conditions: Kidney Disease|Nephropathy|Type 2 Diabetes
Interventions: DRUG: losartan|DRUG: lisinopril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado
Status: COMPLETED
Conditions: Elevated Triglycerides|Hypertriglyceridemia
Interventions: OTHER: Average American Diet With SoFAS Replaced With Avocado|OTHER: Average American Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of VRD-based Regimen Combined With CART-ASCT-CART2 Treatment in Patients With Primary Plasma Cell Leukemia
Status: RECRUITING
Conditions: Plasma Cell Leukemia
Interventions: BIOLOGICAL: anti-BCMA CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) Study
Status: RECRUITING
Conditions: Cognitive Impairment|Disability Physical|Surgery
Interventions: BEHAVIORAL: Comprehensive training program|BEHAVIORAL: Active control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Exercises on Dynamic Balance in Knee Osteoarthritis Patients.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: stretching exercises|COMBINATION_PRODUCT: Transcutaneous electrical nerve stimulation|COMBINATION_PRODUCT: weight bearing strengthening exercises|COMBINATION_PRODUCT: Non-weight bearing strengthening exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Chemotherapy With or Without Nelarabine or Rituximab in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia|Mucositis|Oral Complications
Interventions: BIOLOGICAL: palifermin|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: imatinib mesylate|DRUG: melphalan|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: nelarabine|DRUG: pegaspargase|DRUG: vincristine sulfate|PROCEDURE: allogeneic hematopoietic stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: RADIATION: CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Laparoscopic Ventral Hernia Repair With Routine Defect Closure Using Su2ura® Approximation Device
Status: RECRUITING
Conditions: Ventral Hernia
Interventions: DEVICE: Hernia repair surgery using the Su2ura® approximation device|DIAGNOSTIC_TEST: Physical Examination|DIAGNOSTIC_TEST: Vital Signs|DIAGNOSTIC_TEST: Blood Tests|DIAGNOSTIC_TEST: Urine Pregnancy Test|DIAGNOSTIC_TEST: Abdominal Ultrasound imaging|OTHER: EuraHS-QoL|OTHER: Visual Analouge Scale (VAS)|DIAGNOSTIC_TEST: Clinical evaluation for hernia recurrence and clinical bulging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Inflammatory Markers, Depressive Symptoms, and Heart Disease
Status: TERMINATED
Conditions: Depression|Coronary Artery Disease (CAD)|Acute Coronary Syndrome (ACS)
Interventions: DRUG: Sertraline (Zoloft)|DRUG: Simvastatin (Zocor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat, Cladribine, and Rituximab in Treating Patients With Mantle Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, or Relapsed B Cell Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Indolent Adult Non-Hodgkin Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Cladribine|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Rituximab|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostatic Cancer|Androgen-Independent Prostatic Cancer|Androgen-Insensitive Prostatic Cancer|Androgen-Resistant Prostatic Cancer|Hormone Refractory Prostatic Cancer|Anal Cancer|Anal Neoplasm|Carcinoma, Squamous Cell of Head and Neck|Head and Neck Squamous Cell Carcinoma|Laryngeal Squamous Cell Carcinoma|Oral Squamous Cell Carcinoma|Malignant Melanoma|Melanoma|Non-small Cell Lung Cancer|Non-small Cell Carcinoma|Small-cell Lung Cancer|Small Cell Carcinoma
Interventions: BIOLOGICAL: vobramitamab duocarmazine 2.0 mg (Arm A)|BIOLOGICAL: vobramitamab duocarmazine 2.7 mg (Arm B)|BIOLOGICAL: vobramitamab duocarmazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular (Wet) Age-Related Macular Degeneration
Interventions: DRUG: aflibercept|DRUG: High-dose aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Fully Automated Lyumjev and Pramlintide Delivery System for Adults With Type 1 Diabetes
Status: RECRUITING
Conditions: type1diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Pramlintide|DRUG: Lyumjev|DEVICE: Automated Insulin Delivery (AID) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Viral Conjunctivitis
Status: COMPLETED
Conditions: Adenoviral Conjunctivitis
Interventions: DRUG: IVIEW-1201|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effects of Ba-Duan-Jin Based Deep Breathing Exercises and Forced Expiratory Technique
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Ba-Duan-Jin Based Deep Breathing Exercises|OTHER: FET (Forced Expiratory Technique)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ph II Study to Evaluate Olaparib With Abiraterone in Treating Metastatic Castration Resistant Prostate Cancer.
Status: COMPLETED
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: Olaparib|DRUG: Placebo|DRUG: Abiraterone|DRUG: Prednisone or prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy in Chronic Ischemic Heart Failure
Status: COMPLETED
Conditions: Myocardial Ischemia|Heart Failure, Congestive
Interventions: PROCEDURE: Bone marrow transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae
Status: RECRUITING
Conditions: Head and Neck Cancer|Oral Cavity Cancer|Oropharynx Cancer
Interventions: PROCEDURE: Oropharyngeal or oral cavity reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Does Cervical Mobilization Have an Effect on Hand Function in Patients With Double Crush Syndrome?
Status: COMPLETED
Conditions: Double Crush Syndrome
Interventions: OTHER: Cervical Mobilization|OTHER: Traditional physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Copeptin After an Oral Stimulation With Macimorelin in Healthy Volunteers
Status: COMPLETED
Conditions: Polyuria-polydipsia Syndrome
Interventions: DRUG: Macimorelin 0.5mg/kg body weight|DRUG: Macimorelin 0.75mg/kg body weight
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of a Resiliency Intervention for Siblings of Children With Autism Spectrum Disorder (ASD)
Status: COMPLETED
Conditions: Stress
Interventions: BEHAVIORAL: Relaxation Response Resiliency Program for Siblings of Children with ASD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Diagnosis of Idiopathic Interstitial Pneumonias: a Prospective Study
Status: RECRUITING
Conditions: Idiopathic Interstitial Pneumonia|Idiopathic Pulmonary Fibrosis|Nonspecific Interstitial Pneumonia
Interventions: DIAGNOSTIC_TEST: Microarray analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Performance Evaluation of the truSculpt Radiofrequency Device for Lipolysis of Abdominal Fat
Status: COMPLETED
Conditions: Body Fat
Interventions: DEVICE: Cutera truSculpt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ABP 215 Versus Bevacizumab in Chinese Subjects With Advanced Non-Squamous Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Metastatic Non-small Cell Lung Cancer (NSCLC)|Non-squamous NSCLC
Interventions: DRUG: ABP 215|DRUG: Bevacizumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microtable® Method for Cochlear Implantation Investigational Device Exemption (IDE)
Status: NOT_YET_RECRUITING
Conditions: Hearing Loss, Cochlear
Interventions: DEVICE: The Microtable® Stereotactic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbial Adhesion to Metallic Versus Non Metallic Surfaces of Bounded Removable Partial Denture
Status: UNKNOWN
Conditions: Polyetheretherketone
Interventions: DEVICE: PEEK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interventional Study on the Impact of the Hypnosis Used as Sedation or Relaxation in the Breast Oncologic Surgery
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: PROCEDURE: General anesthesia|PROCEDURE: Hypnosis sedation|PROCEDURE: General anesthesia with preoperative session of hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of One Course of Amevive in Taiwan Patients
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Alefacept (Amevive)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: A Study of the Efficacy and Safety of Omalizumab (Xolair) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine (H1) Treatment
Status: COMPLETED
Conditions: Chronic Idiopathic Urticaria
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma
Status: COMPLETED
Conditions: Endometrial Atypical Hyperplasia|Endometrial Adenocarcinoma
Interventions: DRUG: Megestrol acetate and metformin|DRUG: Megestrol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoanalgesia vs. Epidural in the Nuss Procedure
Status: COMPLETED
Conditions: Pectus Excavatum|Funnel Chest
Interventions: DEVICE: Cryoanalgesia|DRUG: Thoracic epidural (ropivicaine, fentanyl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Artificial Intelligence Supported and Nurse-Led Online Breastfeeding Counseling
Status: NOT_YET_RECRUITING
Conditions: Artificial Intelligence|Nursing Caries|Breastfeeding|Breast Feeding, Exclusive
Interventions: OTHER: 1) Artificial intelligence supported working group|OTHER: Online breastfeeding counseling group led by a nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Joint Use of Electrocardiogram and Transthoracic Echocardiography With Other Clinico-biological Parameters in an Observational Study to Monitor Cardio-vascular Events and Predict Outcomes in Patients Diagnosed With COVID-19
Status: COMPLETED
Conditions: COVID-19|Myocardial Injury|Myocarditis
Interventions: DIAGNOSTIC_TEST: Electrocardiogram, transthoracic echocardiography and clinico-biological parameters in routine care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of the Combination of Tirabrutinib and Entospletinib With and Without Obinutuzumab in Adults With Chronic Lymphocytic Leukemia (CLL)
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Tirabrutinib|DRUG: Entospletinib|DRUG: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Brain Activity During Spinal Cord Stimulation in Failed Back Surgery Syndrome Using Functional MRI and MRS
Status: UNKNOWN
Conditions: Failed Back Surgery Syndrome
Interventions: OTHER: fMRI and MRS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-radiographic Axial Spondyloarthritis
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Tendon Neuroplastic Training (TNT) in Lateral Epicondylitis.
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Tendon neuroplastic training (TNT)|OTHER: group B Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: OGX-427|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides
Status: UNKNOWN
Conditions: Wegener's Granulomatosis|Churg-Strauss Syndrome|Microscopic Polyangiitis|Polyarteritis Nodosa
Interventions: DRUG: Methotrexate|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatment
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Venetoclax|DRUG: ABBV-838|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of FOLFIRINOX Chemotherapy in IV Stage Colorectal Cancer Patients Previously Exposed to Irinotecan, Fluoropyrimidine and Oxaliplatin
Status: UNKNOWN
Conditions: Colorectal Cancer Stage IV
Interventions: DRUG: mFOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCID-X1 Gene Therapy Via Intravenous Lentiviral (Ivlv-X1) Injection
Status: RECRUITING
Conditions: SCID, X-Linked
Interventions: BIOLOGICAL: Direct intravenous injection of ivlv-X1 lentiviral vector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Kidney Carcinoma|Stage IV Renal Cell Cancer AJCC v7
Interventions: BIOLOGICAL: Bevacizumab|PROCEDURE: Biopsy|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Metastasectomy|BIOLOGICAL: Nivolumab|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in Prosthetic Breast Reconstructions
Status: UNKNOWN
Conditions: Surgical Site Infections
Interventions: DRUG: Prolonged antibiotic treatment|DRUG: Short antibiotic course (standard of care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Parent/Child Dyad Approach to Symptom Screening for Children With Cancer
Status: COMPLETED
Conditions: Pediatric Cancer|Quality of Life|Symptom Screening
Interventions: OTHER: Patient/Proxy-SSPedi|OTHER: Co-SSPedi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lifestyle Eating and Performance (LEAP) Program for the Treatment of Irritable Bowel Syndrome (IBS)
Status: RECRUITING
Conditions: IBS - Irritable Bowel Syndrome
Interventions: DIAGNOSTIC_TEST: Leukocyte Activation Assay (LAA-MRT) / Lifestyle Eating and Performance (LEAP) program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser De-epithelialization for Epithelial Exclusion in Root Coverage Procedure: a Clinical Study
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: DEVICE: LASER deepithelialization|DEVICE: Sham LASER deepithelialization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of NaQuinate in Healthy Volunteers
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: NaQuinate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Assess With Ezefeno Tab. in Patients With Dyslipidemia and T2DM
Status: RECRUITING
Conditions: T2DM (Type 2 Diabetes Mellitus)|Dyslipidemias
Interventions: DRUG: Ezetimibe/fenofibrate (Ezefeno) and moderate-intensity statin|DRUG: Dose escalation of moderate-intensity statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Phone SMS Intervention to Increase Retention in HIV Care Among HIV-Positive MSM in Peru (WELTEL PERU)
Status: ACTIVE_NOT_RECRUITING
Conditions: Retention in Care|Hiv
Interventions: BEHAVIORAL: SMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Segmentation Techniques (Manual Versus Semiautomatic) on the Accuracy of the Reconstructed Mandibular Condyle Using CBCT
Status: RECRUITING
Conditions: Segmentation Techniques
Interventions: RADIATION: CBCT radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: GM-CSF and Thalidomide in Treating Patients Undergoing Surgery for High-Risk Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: sargramostim|DRUG: thalidomide|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Maintenance of Effect After Long-term Treatment of Sativex® in Subjects With Neuropathic Pain
Status: COMPLETED
Conditions: Pain|Peripheral Neuropathy
Interventions: DRUG: Sativex®|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain Outpatients
Status: TERMINATED
Conditions: Cancer: Breakthrough Pain|Cancer: Extreme Pain on Movement
Interventions: DRUG: Morphine|DRUG: Ketamine|DRUG: Placebo|DRUG: Chitosan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Olaparib With Paclitaxel Versus Paclitaxel in Gastric Cancer Patients
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: olaparib|DRUG: paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Mininimum Effective Anaesthetic Volume of Local Anaesthetic in Ultrasound-guided "Shamrock" Lumbar Plexus Block
Status: COMPLETED
Conditions: Mininimum Effective Anaesthetic Volume of Local Anaesthetic
Interventions: OTHER: lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Evaluation of Meningococcal Immune Response Among Children Who Previously Received MenACWY Conjugate Vaccine
Status: COMPLETED
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: Meningococcal (groups A, C, W, and Y) oligosaccharide diphtheria CRM-197 conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Clinical Effect of Two Pharmacokinetics Model of Propofol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Evaluation of propofol effect|DRUG: Evaluation of propofol effect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: UCN-01 (7-Hydroxystaurosporine) to Treat Relapsed T-Cell Lymphomas
Status: TERMINATED
Conditions: Lymphoma, Large-Cell, Ki-1|Lymphoma, T-Cell
Interventions: DRUG: UCN-01 (7-hydroxystaurosporine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Personalized Diet on Cardiometabolic, Microbiome and Metabolomics Profiles in Minority Young Adults
Status: RECRUITING
Conditions: Diet Intervention
Interventions: OTHER: Personalized diet|OTHER: Conventional dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 12- Weeks of Quantitative Weight-bearing Progressive Resistance Exercise Training on Glycemia Control and Improving Muscle Strength With Type 2 Diabetes Combine Pre-sarcopenia.
Status: COMPLETED
Conditions: Twelve Week Quantitative Weight Bearing of Resistance Training Effect on Glycemic Control and Muscle Strength
Interventions: BEHAVIORAL: Quantitative weight -bearing and report exercise sign data every weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Anti-oxidant Therapy and Postoperative Cardiac Events (ACE) Trial, Preoperative Intervention in Vascular Surgery
Status: UNKNOWN
Conditions: Myocardial Injury
Interventions: DRUG: Ubiquinone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health
Status: COMPLETED
Conditions: Aging|Sarcopenia|Disability Physical|Cardiovascular Diseases|Insulin Resistance|Diabetes Mellitus
Interventions: BEHAVIORAL: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: DRUG: Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Smartwatch App for Vibration Stimulation
Status: COMPLETED
Conditions: Stroke|Physical Disability
Interventions: DEVICE: real stimulation|DEVICE: no stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Explorative Randomized Controlled Investigation Evaluating Newly Developed Ostomy Products
Status: COMPLETED
Conditions: Ileostomy
Interventions: DEVICE: Test A|DEVICE: Test B|DEVICE: Baseline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Virtual Reality on Patients With Acute Pain After Thoracoscopic Surgery
Status: COMPLETED
Conditions: Virtual Reality|Acute Postoperative Pain|Thoracic Surgery, Video-Assisted
Interventions: DEVICE: Placebo-VR headsets|DEVICE: QTC-VR headsets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PeeRelease - a Gel Absorbent Pad in Moderate to Severe Urinary Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: OTHER: PeeRelease gel absorbent pad
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Melatonin in Decreasing the Incidence of Delirium in End of Life Patients
Status: COMPLETED
Conditions: Delirium
Interventions: DRUG: Melatonin|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression
Status: RECRUITING
Conditions: Myopia
Interventions: DEVICE: Microstructure lens A|DEVICE: Microstructure lens B|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Bowel Preparation Regimen in Patients With Colorectal Surgery
Status: UNKNOWN
Conditions: Bowel Preparation
Interventions: DRUG: standard preparation (2L PEG-ELS)|DRUG: low-volume preparation (10 mg bisacodyl plus 2L PEG-ELS)|DRUG: high-volume preparation (4L PEG-ELS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamate Reducing Interventions in Schizophrenia
Status: COMPLETED
Conditions: Clinical High Risk for Psychosis
Interventions: DRUG: Pomaglumetad methionil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Olixia Pure® Eye Drops on Tear Film Thickness in Healthy Subjects
Status: COMPLETED
Conditions: Dry Eye Syndrome|Healthy
Interventions: DEVICE: Olixia pure eye drops|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the Effects of the Non-invasive Trigeminal Nerve Stimulation on Ischemic Stroke Patients
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: External trigeminal nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AUGMENTIN™ in Dental Infections
Status: COMPLETED
Conditions: Focal Infection, Dental
Interventions: DRUG: Amoxicillin/clavulanate|DRUG: Clindamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of AAV Gene Therapy in Patients With CNGA3 Achromatopsia (A Clarity Clinical Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Achromatopsia
Interventions: BIOLOGICAL: AGTC-402
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Airway Immune Response to Allergens (Use Lay Language Here)
Status: ACTIVE_NOT_RECRUITING
Conditions: Allergic Asthma|Allergy to Cats|Allergy to Dust Mites|Allergic Rhinitis|Allergic Conjunctivitis
Interventions: BIOLOGICAL: Segmental allergen challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Huashibaidu Granule on Community-acquired Pneumonia in Children
Status: NOT_YET_RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Huashibaidu granule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nilotinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Patients Who Have Received Allo-HSCT
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of LDV/SOF Fixed-Dose Combination (FDC) ± Ribavirin in HCV Genotype 1 Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002)
Status: TERMINATED
Conditions: Healthy|HIV
Interventions: DRUG: Tenofovir disoproxil fumarate intravaginal ring|DRUG: Placebo intravaginal ring (IVR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of an Exergame-based Intervention
Status: RECRUITING
Conditions: Blood Pressure|Physical Inactivity
Interventions: BEHAVIORAL: Exergame Intervention|BEHAVIORAL: Moderate-intensity endurance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Capmatinib (INC280) Plus Pembrolizumab vs Pembrolizumab Alone in NSCLC With PD-L1≥ 50%
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Capmatinib|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Tapentadol Extended-Release (JNS024ER) ) in Japanese Participants With Chronic Pain Due to Diabetic Neuropathic Pain or Postherpetic Neuralgia
Status: COMPLETED
Conditions: Pain|Diabetic Neuropathies|Neuralgia|Postherpetic Neuralgia
Interventions: DRUG: Tapentadol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Using Metronomic Oral Low-dose Cyclophosphamide Alternating With Low-dose Oral Methotrexate With Continuous Celecoxib and Weekly Vinblastine in Children and Adolescents With Relapsed or Progressing soliD Tumours.
Status: COMPLETED
Conditions: Survival Without Progression
Interventions: DRUG: celecoxib, Vinblastine, Cyclophosphamide , methotrexate ,
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-inferiority of PRO-067 Ophthalmic Solution vs GAAP Ofteno® in Glaucoma or Ocular Hypertension
Status: TERMINATED
Conditions: Primary Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: PRO-067|DRUG: GAAP Ofteno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase Ia Dose-Escalation Safety, Pharmacodynamic and Pharmacokinetic Study of Imprime PGG™ Injection
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Imprime PGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Phase I Study of MEDI522 in Patients With Irinotecan-Refractory Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: MEDI-522|DRUG: MEDI-522|DRUG: MEDI-522|DRUG: MEDI-522|DRUG: MEDI-522
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT