pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas
Status: RECRUITING
Conditions: Neurofibromatosis 1
Interventions: DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pretreatment of a Left-sided Double-lumen Tube to Prevent Its Misplacement to the Right Mainstem Bronchus
Status: COMPLETED
Conditions: Double Lumen Tube Intubation
Interventions: DEVICE: Neutral shape of bronchial tip|DEVICE: Bent shape of bronchial tip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Significance of Circulating Microvesicles in Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Hypertension Due to Chronic|Obstructive Pulmonary Disease|Circulating Microvesicles|Circulating Markers of Endothelium Damage
Interventions: PROCEDURE: Catheterization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Thiamine, Vitamin C and Hydrocortisone in the Treatment of Septic Shock
Status: UNKNOWN
Conditions: Septic Shock
Interventions: DIETARY_SUPPLEMENT: Thiamine and Vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Calanus Oil Supplementation and Maximal Oxygen Uptake
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Calanus oil|DIETARY_SUPPLEMENT: placebo dietary oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Chemotherapy With Xelox Follows by TX to Treat Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Capecitabine (Xeloda, Roche), Oxaliplatin (Sanofi-Aventis), Docetaxel (Sanofi-Aventis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sistas Informing Sistas on Topics About AIDS and Prevention (SISTA-P)
Status: RECRUITING
Conditions: Health Behavior, Risky|Health Knowledge, Attitudes, Practice|Health-Related Behavior
Interventions: BEHAVIORAL: SISTA-P Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of ASKG712 in Patients With Neovascular Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: ASKG712
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Investigate The Metabolism And Excretion Of 14C SB-751689 Given To Healthy Males And Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: SB-751689
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lung Ultrasound and Chest Radiography for Pleural and Pulmonary Diagnosis in Pediatric Intensive Care Unit
Status: TERMINATED
Conditions: Pediatric Lung Ultrasound|Pediatric Chest Radiography|Pediatric Lung Diagnosis
Interventions: RADIATION: Chest radiography and lung ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Determine the Effect of Food on the Pharmacokinetics of Abiraterone Acetate in Healthy Male Patients
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Treatment A: abiraterone acetate|DRUG: Treatment B: abiraterone acetate|DRUG: Treatment C: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Opioids: Integrated Treatment In Veterans
Status: RECRUITING
Conditions: Chronic Pain|Opioid-use Disorder|Opioids; Harmful Use
Interventions: BEHAVIORAL: ACT+MBRP|BEHAVIORAL: Education control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strength Training in Female Runners With Patellofemoral Pain
Status: COMPLETED
Conditions: Patellofemoral Syndrome
Interventions: OTHER: Blood Flow Restriction Training (BFRT)|OTHER: Sham Blood Flow Restriction Training (Sham BFRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Highlighting the Benefits of Therapeutic Gardens in Alzheimer's Disease by 18F-FDG Cerebral PET /CT
Status: WITHDRAWN
Conditions: Alzheimer Disease
Interventions: DEVICE: cerebral 18F-FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cardiac Surgery Outcomes in Blood-transfusion Acceptors and no Acceptors
Status: UNKNOWN
Conditions: Thoracic Surgery|Blood Transfusion; Hemoglobinemia|Cardiac Disease
Interventions: OTHER: Non-acceptance of blood-transfusions|OTHER: Acceptance of blood-transfusions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post-anaesthetic Shivering Amongst Patients Undergoing Cerebral Angiography
Status: UNKNOWN
Conditions: Cerebral Angiography|Shivering
Interventions: OTHER: Warmed Isotonic Saline|OTHER: Room-Temperature Isotonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Confirmatory Study of IK-3001 in Japanese Subjects With Peri-/Post-op Pulmonary Hypertension Assoc. With Cardiac Surgery
Status: COMPLETED
Conditions: Hypertension, Pulmonary|Ventricular Dysfunction, Left
Interventions: DRUG: IK-3001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser Treatment of Basal Cell Carcinoma Under Imaging Guidance
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Basal Cell
Interventions: DEVICE: Treatment of basal cell carcinoma with Nd:YAG laser under imaging guidance of optical coherence tomography (OCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Ruxolitinib Evaluation in Chronic Hand Eczema
Status: ACTIVE_NOT_RECRUITING
Conditions: Hand Eczema
Interventions: DRUG: Ruxolitinib cream|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Safety and Efficacy of PLB1004 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: DRUG: PLB1004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pertussis Maternal Immunization Study
Status: COMPLETED
Conditions: Pregnant Women
Interventions: BIOLOGICAL: Tdap|BIOLOGICAL: Td
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Clinical Trial to Evaluate the Efficacy and Safety of VSA006 in Chinese NASH Patients
Status: NOT_YET_RECRUITING
Conditions: Nash
Interventions: DRUG: VSA006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Prediction of Acute Kidney Injury Among Patients Admitted to Surgical ICU
Status: COMPLETED
Conditions: Acute Kidney Injury|Biomarkers
Interventions: DIAGNOSTIC_TEST: ELISA test in urine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Camrelizumab, Pegaspargase and Apatinib With Radiation Therapy for Stage IE/IIE ENKTL
Status: UNKNOWN
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: CAPA indution immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Intervention for Veterans With PTSD and Anger
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Anger
Interventions: BEHAVIORAL: Mobile Intervention for Reducing Anger (MIRA)|BEHAVIORAL: Mindfulness Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Quadrivalent Influenza Vaccine in Children Aged 6~35 Months
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: NBP607-QIV|BIOLOGICAL: NBP607-TIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: NAVISTAR® THERMOCOOL® Catheter for the Radiofrequency Ablation of Symptomatic Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Heart Diseases|Arrhythmia|Atrial Fibrillation
Interventions: DEVICE: NAVISTAR® THERMOCOOL® Catheter|DRUG: Antiarrhythmic drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Biological Augmentation With Subacromial Bursa for Bursal Side Partial-thickness Rotator Cuff Tears
Status: COMPLETED
Conditions: Partial Thickness Rotator Cuff Tears
Interventions: PROCEDURE: Augmentation with subacromial bursa + acromioplasty|PROCEDURE: Rotator cuff debridement + acromioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty
Status: RECRUITING
Conditions: Analgesia|Postoperative Pain, Acute
Interventions: PROCEDURE: Pericapsular Nerve Group (PENG) Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Induced Diuresis With Matched Hydration Compared to Standard Hydration for Contrast Induced Nephropathy (CIN) Prevention
Status: UNKNOWN
Conditions: Contrast Induced Nephropathy
Interventions: DRUG: Furosemide and matched saline hydration|DRUG: isotonic saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gastric pH in Critically Ill Patients
Status: COMPLETED
Conditions: Critically Ill Patients|Indication for Stress Ulcer Prophylaxis
Interventions: DRUG: esomeprazole|DRUG: ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A POC and Dose-Ranging Study of HTD1801 in PSC Patients
Status: COMPLETED
Conditions: Primary Sclerosing Cholangitis (PSC)
Interventions: DRUG: HTD1801|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging Using Radiolabeled Atezolizumab to Assess Atezolizumab Biodistribution in Lymphoma Patients
Status: WITHDRAWN
Conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Interventions: OTHER: 89Zr-atezolizumab PET scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Percutaneous Vertebroplasty Using Rotary Cutter for Bone Metastases
Status: RECRUITING
Conditions: Metastasis
Interventions: DEVICE: Conventional Percutaneous Vertebroplasty|DEVICE: Percutaneous Vertebroplasty with Rotary Cutter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Wearable Nerve Stimulator for Chronic Migraine/Headache and Mood Disturbance in Adolescents
Status: RECRUITING
Conditions: Migraine in Adolescence|Headache|Mood Disturbance
Interventions: DEVICE: Apollo Neuro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Infusion for Adolescent Depression and Anxiety
Status: COMPLETED
Conditions: Major Depressive Disorder|Anxiety Disorder
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ribociclib and Letrozole in Treating Patients With Relapsed ER Positive Ovarian, Fallopian Tube, Primary Peritoneal, or Endometrial Cancer
Status: COMPLETED
Conditions: Estrogen Receptor Positive|Postmenopausal|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Recurrent Uterine Corpus Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Letrozole|DRUG: Ribociclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioavailability of Desogestrel 0.075 mg Tablets With Regards to Reference Product
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Desogestrel 0.075 MG|DRUG: Desogestrel 0.075 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of of 24 Hour Spirometry Profiles of Inhaled BI 1744 CL and Inhaled Tiotropium Bromide in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Olodaterol (BI1744) Low|DRUG: Olodaterol (BI1744) High|DRUG: Tiotropium 18 mcg|DRUG: Placebo (for Olodaterol (BI1744)l)|DRUG: Placebo (for Tiotropium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Metastatic Bladder Cancer at the Time Of Biochemical reLApse Following Radical Cystectomy
Status: RECRUITING
Conditions: Bladder Cancer|Bladder Cancer, Metastatic
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of 1 g and 2 g of Cefazolin in Pediatric Subjects
Status: TERMINATED
Conditions: Postoperative Infection
Interventions: DRUG: Cefazolin 1 g Infusion|DRUG: Cefazolin 2 g Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-label Investigation of the Safety and Efficacy of DIABECELL in Patients With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: DIABECELL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osteopathic Thrust and Muscle-energy Manipulations on Sacroiliac Joint Dysfunction
Status: UNKNOWN
Conditions: Sacroiliac Disorder
Interventions: OTHER: Osteopathic manipulation type thrust|OTHER: Osteopathic manipulation type muscle-energy|OTHER: Placebo technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Ibrutinib Plus Trastuzumab in HER2-amplified Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Neoplasms|Malignant Neoplasm of Breast
Interventions: DRUG: Trastuzumab|DRUG: Ibrutinib 560 mg|DRUG: Ibrutinib 840 mg|DRUG: Ibrutinib 420 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-marketing Surveillance of Linaclotide Tablet in Patients With Irritable Bowel Syndrome With Constipation or Chronic Constipation (Excluding Constipation Due to Organic Diseases)
Status: COMPLETED
Conditions: Chronic Constipation (CC) (Excluding Constipation Due to Organic Diseases)|Irritable Bowel Syndrome With Constipation (IBS-C)
Interventions: DRUG: linaclotide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma
Status: TERMINATED
Conditions: Metastatic Soft-tissue Sarcoma
Interventions: DRUG: NOX66|DRUG: NOX66|DRUG: NOX66|DRUG: NOX66|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study of CA-008 (Vocacapsaicin) in Patients Undergoing Ventral Hernia Repair
Status: COMPLETED
Conditions: Postsurgical Pain
Interventions: DRUG: CA-008 (vocacapsaicin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders
Status: COMPLETED
Conditions: Musculoskeletal Disorders|Whiplash
Interventions: BEHAVIORAL: Value-based cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telmisartan/Amlodipine (80/5) vs. Telmisartan/Amlodipine (40/5) vs. Amlodipine 10 or 5 in Resistant Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: fixed dose combination of telmisartan+amlodipine|DRUG: amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease)
Status: COMPLETED
Conditions: Mitral Regurgitation
Interventions: DRUG: metoprolol succinate (Toprol XL)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Riboflavin-Enhanced Hyaluronic Acid Eye Drops in Treating Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: modified hyaluronic acid 0.1% covalently linked to Riboflavin|DRUG: hyaluronic acid 0.1%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose-Escalate Study to Investigate the Safety and Tolerability of T89 in Japanese
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: T89 Group A|DRUG: Placebo Group A|DRUG: Placebo Group B|DRUG: T89 Group B|DRUG: Placebo Group C|DRUG: T89 Group C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Study of the Histone-deacetylase Inhibitor JNJ-26481585 in Patients With Advanced or Refractory Leukemia or Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Advanced or Refractory Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: JNJ-26481585
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Peripheral Intravenous Catheter Insertion Site and Catheter-related Complications in Antimicrobial Therapy
Status: RECRUITING
Conditions: Antimicrobial
Interventions: DEVICE: insert catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Mycophenolate Versus Cyclophosphamide in ANCA Vasculitis
Status: COMPLETED
Conditions: Vasculitis
Interventions: DRUG: mycophenolate mofetil|DRUG: cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Mode of Action of Anti-TNF, Reverse Signaling, in Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DIAGNOSTIC_TEST: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase IV Study to Assess the Safety of EupentaTM Inj
Status: UNKNOWN
Conditions: Hepatitis B|Diphtheria|Haemophilus Influenzae Type B Infection|Tetanus|Pertussis
Interventions: BIOLOGICAL: Eupenta Inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens With Metabolic Syndrome
Status: COMPLETED
Conditions: NAFLD|Fatty Liver|Obesity|Metabolic Syndrome
Interventions: OTHER: Diet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First in Human Study to Assess the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of QCC374
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: QCC374|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optical Coherence Tomography of the Saphenous Vein Graft
Status: RECRUITING
Conditions: Coronary Bypass Graft Stenosis
Interventions: DEVICE: OCT-guided saphenous vein CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Urocortins in Patients With Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Endothelium
Interventions: DRUG: Urocortin 2, Urocortin 3 and Substance P
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Helicobacter Pylori Eradication Rates of Bismuth-containing Quadruple Therapy vs Modified Quadruple Therapy in Korea
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: PAMB treatment (modified quadruple therapy)|DRUG: PBMT treatment (bismuth-containing quadruple therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Study Of Once Daily Controlled Release Pregabalin In The Treatment Of Patients With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Post Herpetic Neuralgia
Interventions: DRUG: Pregabalin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia
Status: COMPLETED
Conditions: Hypertensive Heart Disease
Interventions: DRUG: Safflower (Carthamus Tinctorius) IgG4 &#X7C; Serum &#X7C; Allergy|DRUG: Atropine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mitigating the Pro-inflammatory Phenotype of Obesity
Status: RECRUITING
Conditions: Blood Pressure|Diabetes|Obesity|Insulin Resistance|Diuretics Drug Reactions|Sympathetic Nerve Activity
Interventions: DRUG: Hydrochlorothiazide 12.5Mg Tab|DRUG: Clonidine Pill|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Viral Conjunctivitis Treatment Study
Status: TERMINATED
Conditions: Viral Conjunctivitis
Interventions: DEVICE: 0.01% Hypochlorous acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Activity & Safety Study of KX2-391 Ointment in Participants With Actinic Keratosis on the Face or Scalp
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: 50 mg of KX2-391 Ointment 1%|DRUG: 50 mg of KX2-391 Ointment 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Naproxen Capsules to Treat Dental Pain
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Naproxen Test|DRUG: Naproxen Test|DRUG: Naprosyn|DRUG: Naprosyn|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Etodolac Capsules USP 300 mg Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Etodolac Capsules USP 300 mg|DRUG: Etodolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IRI-EXPLORE: A Study to Test Whether BI 765845 Helps People Who Have Had a Heart Attack
Status: RECRUITING
Conditions: Myocardial Infarction
Interventions: DRUG: BI 765845|DRUG: Placebo matching BI 765845
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Implant Healing Abutment and Chlorhexidine
Status: COMPLETED
Conditions: Periimplantitis
Interventions: DRUG: Chlorhexidine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity
Status: COMPLETED
Conditions: Apnea of Prematurity
Interventions: OTHER: CO2 inhalation|DRUG: Theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Rebamipide for Non-steroidal Anti-inflammatory Drugs (NSAID) - Induced Small-intestinal Injuries
Status: UNKNOWN
Conditions: NSAIDs-induced Small-intestinal Injuries
Interventions: DRUG: Rebamipide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
Status: COMPLETED
Conditions: Hernia Repair With Compartment Syndrome
Interventions: DEVICE: Flex HD|DEVICE: Strattice
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic
Status: TERMINATED
Conditions: Hypertriglyceridemia
Interventions: DRUG: Liposyn III 20% (lipid infusion)|DRUG: Intralipid 20% (lipid infusion)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study of BI-505 in Conjunction With Autologous Stem Cell Transplant in Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: BI-505|OTHER: High dose melphalan|OTHER: Autologous stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Texture Changing Coatings for Use in At-Home Rapid Tests
Status: NOT_YET_RECRUITING
Conditions: Vision, Low|Blindness
Interventions: DIAGNOSTIC_TEST: Interaction with Mock COVID-19 Rapid Antigen Test and Reference Surfaces|DIAGNOSTIC_TEST: Biomechanical Measurements|BEHAVIORAL: Psychophysical Tasks
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine and Idarubicin|DRUG: CPX-315
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intercostal CryoAnalgesia in Robotic Lung Resection
Status: RECRUITING
Conditions: Pain, Postoperative|Lung Diseases
Interventions: DEVICE: Intercostal Nerve Cryoablation|DRUG: Patient-controlled analgesia (PCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Pharmacokinetics, and Efficacy of Rociletinib (CO-1686) in Previously Treated Mutant Epidermal Growth Factor Receptor (EGFR) in Non-Small Cell Lung Cancer (NSCLC) Patients
Status: TERMINATED
Conditions: Locally Advanced or Metastatic Non Small Cell Lung Cancer
Interventions: DRUG: Rociletinib|DRUG: Rociletinib|DRUG: Rociletinib|DRUG: Rociletinib|DRUG: Rociletinib|DRUG: Rociletinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD
Status: COMPLETED
Conditions: Leukemia, Mast-Cell|Mantle-cell Lymphoma
Interventions: PROCEDURE: Total lymphoid irradiation|DRUG: Rituximab|DRUG: Anti-thymoglobulin, rabbit (ATG, rabbit ATG)|DRUG: Cyclosporine|DRUG: Mycophenylate mofetil|DRUG: Filgrastim|DRUG: Granisetron|DRUG: Solumedrol|DRUG: Acetaminophen|DRUG: Diphenhydramine|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measuring Sleep Quality In Patients That Posterior Spinal Instrumentatıon Plannıng
Status: COMPLETED
Conditions: Sleep Disorder|Sleep, Inadequate|Total ıntravenous Anesthesia|Inhalation Anesthesia
Interventions: OTHER: Total ıntravenous anesthesia with propofol and remifentanil for anesthetic maintenance|OTHER: Inhalation anesthesia with sevoflurane for anesthetic maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scripps Wired for Health Monitoring Study
Status: COMPLETED
Conditions: Diabetes|Hypertension|Cardiac Arrhythmia
Interventions: DEVICE: DM Pgm + device|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: High Dose Chemo With Autologous BMT for Treatment of Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: High-Dose Chemo with Autologous BMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Hodgkin Lymphoma, B-cell
Interventions: BIOLOGICAL: CD19/CD20/BCMA CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome
Status: COMPLETED
Conditions: Nephrotic Syndrome|Hyperlipidemia
Interventions: DRUG: Pravastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Active Lifestyle All Your Life-an Intervention Programme for Preventing Fall Injuries
Status: COMPLETED
Conditions: Frequency of Accidental Falls|Participation|Self-rated Health|Occupational Gaps
Interventions: BEHAVIORAL: Active Lifestyle all your Life
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-552 Capsules Moves Through the Body of Participants Aged 50 to 90 Years With Mild Alzheimer's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Alzheimer's Disease (AD)
Interventions: DRUG: ABBV-552|DRUG: Placebo for ABBV-552
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC)
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Nicotinamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: cyclophosphamide|DRUG: filgrastim|DRUG: methylprednisolone|PROCEDURE: Autologous Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Flumazenil on Recovery From General Anesthesia With Isoflurane
Status: COMPLETED
Conditions: Adverse Effect of Other General Anesthetics
Interventions: DRUG: Flumazenil|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Application for the Etonogestrel/Ethinyl Estradiol Ring
Status: UNKNOWN
Conditions: Emergency Contraception|Healthy, Reproductive Age Women
Interventions: DRUG: Etonogestrel/ethinyl estradiol contraceptive vaginal ring
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Endometrial Cavity After Endometrial Ablation
Status: TERMINATED
Conditions: Menorrhagia
Interventions: DEVICE: Genesys HydroTherm Ablator|DEVICE: radiofrequency energy ablation device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlamydia and Mycoplasma in Coronary Artery Disease
Status: COMPLETED
Conditions: Atherosclerosis|Coronary Artery Disease|Chlamydia Infections|Mycoplasma Infections
Interventions: OTHER: blood sample analysis - mycoplasma and chlamydia antibodies
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Success of Single-Color Universal Resin Composites
Status: RECRUITING
Conditions: Dental Caries Class II
Interventions: OTHER: Clearfil Majesty Posterior|OTHER: Omnichroma Universal Group|OTHER: Zen Universal Group|OTHER: Vittra Aps Unique Universal Group|OTHER: Charisma Diamond Universal Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.
Status: RECRUITING
Conditions: Liver Tumor; Surgery
Interventions: DRUG: Indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of White Spot Lesions Using Bioactive Gel
Status: NOT_YET_RECRUITING
Conditions: White Spot Lesions
Interventions: DRUG: giomer based bioactive gel|DRUG: Fluoride gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inactivated Split Virus Seasonal Influenza Vaccine (Vero Cell-Derived)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Vero cell-derived trivalent influenza vaccine manufactured with the modified manufacturing process (VCIV modified)|BIOLOGICAL: VCIV manufactured with the current manufacturing process (VCIV current)|BIOLOGICAL: Fluzone®, licensed trivalent influenza vaccine (TIV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Controlled Study of ONO-5920 in Patients With Involutional Osteoporosis in Japan
Status: COMPLETED
Conditions: Involutional Osteoporosis
Interventions: DRUG: Minodronic acid hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled Study of Fecal Microbiota Transplant (FMT) for a First or Second Episode of C. Difficile Infection in Adults Using a Frozen Encapsulated Inoculum
Status: TERMINATED
Conditions: Clostridium Difficile
Interventions: BIOLOGICAL: Fecal Microbiota Transplant|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery
Status: COMPLETED
Conditions: Peri-operative Hemorrhage or Hematoma|Surgery|Retrognathism
Interventions: DRUG: Tranexamic Acid|DRUG: saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levo-Dexa vs. Tobra+Dexa for Prevention and Treatment of Inflammation and Prevention of Infection in Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: Levofloxacin + dexamethasone followed by dexamethasone|DRUG: Tobramycin + Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laryngeal Vibro-tactile Stimulation as a Non-invasive Symptomatic Treatment for Spasmodic Dysphonia
Status: NOT_YET_RECRUITING
Conditions: Adductor Spasmodic Dysphonia|Abductor Spastic Dysphonia|Laryngeal Dystonia
Interventions: DEVICE: vibro-tactile stimulation (VTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ubiquitous SR-based Memory Advancement and Rehabilitation Training (U-SMART)
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: Phase I U-SMART (4 wks)|OTHER: Washout (2 wks)|DEVICE: Phase II U-SMART (4 wks)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The International Nocturnal Oxygen (INOX) Trial
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Nocturnal Desaturation
Interventions: DEVICE: Concentrator|DEVICE: Sham concentrator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Vedolizumab Following Multiple Intravenous Doses in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Vedolizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia
Status: COMPLETED
Conditions: Induction and Maintenance of General Anesthesia
Interventions: DRUG: HSK3486|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Two StereoTactic Ablative Adaptive Radiotherapy Treatments for Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: Stereotactic Ablative Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Chronic Obstructive Pulmonary Disease (COPD) Patients' Treatment Compliance and Quality of Life Via Telemedicine
Status: COMPLETED
Conditions: Telehealth|Copd
Interventions: PROCEDURE: Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effect of High Flow Oxygen Therapy in Spontaneous Breathing Trial on Weaning in Mechanical Ventilated Patients
Status: UNKNOWN
Conditions: Weaning|Mechanical Ventilation|Extubation
Interventions: PROCEDURE: High flow oxygen therapy in spontaneous breathing trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Intraosseous Antibiotics Improve the Results of Irrigation & Debridement and Prosthetic Retention for PJI?
Status: ENROLLING_BY_INVITATION
Conditions: Joint Infection
Interventions: DRUG: Intraoperative Intraosseous Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Oral Bioavailability of New ABT-263 Formulations
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Lymphomas|Leukemias
Interventions: DRUG: ABT-263|DRUG: ABT-263|DRUG: ABT-263
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
Status: RECRUITING
Conditions: Glioblastoma
Interventions: RADIATION: Radiation Therapy|BIOLOGICAL: Personalized NeoAntigen Vaccine|DRUG: Pembrolizumab|DRUG: Temozolomide|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: Control Lens (stenfilcon A)|DEVICE: Test Lens (senofilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
Status: COMPLETED
Conditions: Schizophrenia|Autistic Disorder
Interventions: OTHER: Facial recognition of emotions|OTHER: understanding metaphors|OTHER: Attribution of intentionality to others in social situations depending on the type of situation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Icotinib as an Adjuvant Therapy for Patients With Stage IIA-IIIA Adenocarcinoma With EGFR Mutation
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Icotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation Followed By Infusion of White Blood Cells in Treating Patients With AIDS-Related Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclophosphamide|DRUG: cyclosporine|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphoma
Status: WITHDRAWN
Conditions: Recurrent Classic Hodgkin Lymphoma|Refractory Classic Hodgkin Lymphoma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Bendamustine|DRUG: Brentuximab Vedotin|DRUG: Carboplatin|PROCEDURE: Computed Tomography|DRUG: Etoposide|DRUG: Gemcitabine|DRUG: Ifosfamide|DRUG: Pegylated Liposomal Doxorubicin Hydrochloride|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|RADIATION: Radiation Therapy|OTHER: Transplant Conditioning|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT