pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Rituximab, Lenalidomide, and Ibrutinib in Treating Patients With Previously Untreated Stage II-IV Follicular Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Ann Arbor Stage II Grade 1 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 1 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 2 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 2 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma|Ann Arbor Stage II Grade 3 Non-Contiguous Follicular Lymphoma|Ann Arbor Stage III Grade 1 Follicular Lymphoma|Ann Arbor Stage III Grade 2 Follicular Lymphoma|Ann Arbor Stage III Grade 3 Follicular Lymphoma|Ann Arbor Stage IV Grade 1 Follicular Lymphoma|Ann Arbor Stage IV Grade 2 Follicular Lymphoma|Ann Arbor Stage IV Grade 3 Follicular Lymphoma
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rocuronium Dose Finding Study After Single-shot or Steady-state Propofol Anesthesia
Status: COMPLETED
Conditions: Neuromuscular Blockade|Anesthesia
Interventions: DRUG: Single-Shot Propofol|DRUG: 30min infusion Propofol|DRUG: Remifentanil infusion|DRUG: Rocuronium (0.07mg/kg/body mass)|DRUG: Rocuronium (0.1mg/kg/body mass)|DRUG: Rocuronium (0.15mg/kg/body mass)|DRUG: Rocuronium (0.2mg/kg/body mass)|DRUG: Rocuronium (0.3mg/kg/body mass)|DRUG: Rocuronium (0.45mg/kg/body mass)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Specific Immunotherapy With Recombinant Major Allergens of Timothy Grass Pollen Adsorbed Onto Aluminium-hydroxide in Patients With IgE-mediated Allergic Rhinoconjunctivitis +/- Controlled Asthma
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: BIOLOGICAL: AL0704rP|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of The Effectiveness of Spinal Manipulation and Yoga in Chronic Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain|Spinal Manipulation|Yoga
Interventions: OTHER: Chiropractic Manipulation (HVLA - High Velocity Low Amplitude)|OTHER: Yoga-Based Exercise Program|OTHER: Conventional Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFICACY OF ANSA (Experimental Drug) & CRAN MAX (Control Drug) SACHET
Status: RECRUITING
Conditions: Treatment Compliance
Interventions: DRUG: to evaluate the safety and efficacy of Ansa for the treatment of UTi and control of Ecoli infection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF
Status: COMPLETED
Conditions: Primary Myelofibrosis (PMF)|Post-polycythemia Vera (Post-PV)|Post-essential Thrombocythemia Myelofibrosis (Post-ET MF)
Interventions: DRUG: Momelotinib|DRUG: Best Available Therapy (BAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training
Status: COMPLETED
Conditions: Exercise
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: HMB-FA|PROCEDURE: High Intensity Interval Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of the Strategy of "One-stop" Endovascular Treatment for Concomitant Coronary Artery Disease and Aortic Atherosclerotic Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease|Aortic Atherosclerotic Disease
Interventions: PROCEDURE: One-stop strategy group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Catheter-associated Urinary Tract Infection With a Daily Nursing Review of the Indication
Status: COMPLETED
Conditions: Urinary Tract Infections|Urinary Tract; Accessory
Interventions: OTHER: Daily review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immunogenicity of Co-administration of Candidate Influenza Vaccine MVA-NP+M1 and Viroflu® Seasonal Influenza Vaccine
Status: TERMINATED
Conditions: Influenza
Interventions: BIOLOGICAL: Viroflu® and MVA-NP+M1|BIOLOGICAL: Viroflu® and saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Human Coronavirus-immune Convalescent Plasma for the Treatment of COVID-19 Disease in Hospitalized Children
Status: WITHDRAWN
Conditions: Hospitalized Children|Covid-19 Infection
Interventions: BIOLOGICAL: Convalescent plasma (CP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dutch National ITB Study in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Spasticity
Interventions: DRUG: baclofen, intrathecal|DEVICE: infusion pump for intrathecal baclofen, Synchromed, Medtronic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Metformin|DRUG: Glucophage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: BEHAVIORAL: Fitbit Data Collection|BEHAVIORAL: Nutrition Counseling|BEHAVIORAL: Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Envarsus Neurotoxicity Burden in Liver Transplant Patients
Status: COMPLETED
Conditions: Neurotoxicity|Liver Transplant; Complications
Interventions: DRUG: Envarsus|DRUG: Tacrolimus Immediate release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating a Stereotactic Boost/Treatment for Recurrent or Metastatic Cancer of the Head and Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Head and Neck Carcinoma|Head and Neck Cancer Metastatic|Head or Neck Cancer
Interventions: RADIATION: Intensity Modulated Radiation Therapy (IMRT)|DRUG: Cisplatin|RADIATION: Stereotactic Body Radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of CC-93538 in Adult and Adolescent Japanese Participants With Eosinophilic Gastroenteritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Eosinophilic Gastroenteritis
Interventions: DRUG: CC-93538|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibreoptic Bronchoscopy Assisted Intubation During Noninvasive Positive Pressure Ventilation
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: PROCEDURE: Bag-mask ventilation|PROCEDURE: Noninvasive positive pressure ventilation(NIPPV)|PROCEDURE: fibreoptic bronchoscopy assisted intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Corticotropin Releasing Hormone (CRH) on the Sleep in Patients With Hypopituitarism
Status: COMPLETED
Conditions: Hypopituitarism
Interventions: OTHER: corticotropin releasing hormone (CRH)|OTHER: Placebo|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Facilitating Neuroplastic Changes of Acute Stroke Survivors
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Motor relearning training|DEVICE: Passive stretching|DEVICE: Gamed-based active movement training|DEVICE: Passive movement|DEVICE: Active movement training|DEVICE: Ankle torque and motion measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting With Acute Coronary Syndrome Treated With Losmapimod Compared to Placebo (LATITUDE-TIMI 60)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Losmapimod 7.5 mg twice daily|DRUG: Placebo twice daily|DRUG: Standard therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of Lucinactant for Inhalation in Premature Neonates 26 to 32 Weeks Gestational Age
Status: COMPLETED
Conditions: Respiratory Distress Syndrome
Interventions: DRUG: Lucinactant delivered via investigational delivery device|DRUG: nCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Papilocare®: Effects on Regression of Histologically Confirmed Cervical Intraepithelial Lesions 1 and Tolerance
Status: COMPLETED
Conditions: Squamous Intraepithelial Lesions of the Cervix|Human Papilloma Virus Infection|Cervix Lesion
Interventions: DEVICE: PAPILOCARE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental fMRI Study of Guanfacine and Lisdexamfetamine in ADHD Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: ADHD
Interventions: DRUG: Lisdexamfetamine dimesylate|DRUG: Guanfacine Extended Release Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acupuncture or Medication in Reducing Pain in Postmenopausal Women With Breast Cancer and Joint Pain
Status: TERMINATED
Conditions: Breast Cancer|Menopausal Symptoms|Pain
Interventions: PROCEDURE: acupuncture therapy|PROCEDURE: pain therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial to Examine the Efficacy of a Supplement to Support Hormone Regulation in Women
Status: ACTIVE_NOT_RECRUITING
Conditions: Hormone Regulation
Interventions: DIETARY_SUPPLEMENT: Beyond Hormone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate in Oblique Subcostal TAP Block
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain Management
Interventions: DRUG: Bupivacaine plus normal saline|DRUG: Bupivacaine plus normal saline containing MgSO4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cuffed Versus Uncuffed Tracheal Tubes in Neonates Undergoing Elective Surgery
Status: COMPLETED
Conditions: Anesthesia, Endotracheal|Neonate
Interventions: DEVICE: Cuffed ETT (Microcuff®, Halyard Health Inc., Atlanta, GA, USA)|DEVICE: Uncuffed ETT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dispensing Clinical Trial of a Study Test Silicone Hydrogel Lens Against Control Lens Over 1 Week
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: silicone hydrogel lens (test)|DEVICE: enfilcon A lens (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ALVR106 in Patients With Respiratory Viral Infections After Hematopoietic Cell and Solid Organ Transplant
Status: TERMINATED
Conditions: Respiratory Tract Viral Infections|Human Metapneumovirus (hMPV) Infection|Parainfluenza (PIV) Infection|Respiratory Syncytial Viral (RSV) Infection|Influenza Infection
Interventions: BIOLOGICAL: ALVR106|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Clonidine Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease:
Status: COMPLETED
Conditions: Parkinson's Disease|Mpulse Control Disorders
Interventions: DRUG: placebo|DRUG: Clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors
Status: COMPLETED
Conditions: Advanced Neuroendocrine Tumors of Pancreatic Origin
Interventions: DRUG: Everolimus|DRUG: Everolimus Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Sperm Epigenetics in Embryonic Development.
Status: COMPLETED
Conditions: Male Infertility|Epigenetic Disorder
Interventions: DIAGNOSTIC_TEST: Obtaining one or semen samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Siltuximab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis
Status: WITHDRAWN
Conditions: Myelofibrosis|Polycythemia Vera|Primary Myelofibrosis|Thrombocytopenia
Interventions: PROCEDURE: Bone Marrow Aspiration and Biopsy|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Siltuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quality of Ventilation With Facial Versus Nasal Mask vs Nasal Mask Anesthesia in Children 3 to 12 Years Old
Status: COMPLETED
Conditions: Ventilation|Intubation Complication|Intubation; Difficult or Failed
Interventions: DEVICE: Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants.
Status: COMPLETED
Conditions: Apnea|Infant, Premature|Bronchopulmonary Dysplasia
Interventions: PROCEDURE: Nasal Continuous Positive Airway Pressure|PROCEDURE: Synchronized Nasal Positive Pressure Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet Rich Fibrin(PRF) Injection for Treatment of Dental Pulp Exposure:Randomized Clinical Trial
Status: UNKNOWN
Conditions: Dental Pulp Exposure|Dental Caries
Interventions: PROCEDURE: PRF pulp capping|PROCEDURE: MTA pulp capping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mindful Self-Compassion (MSC) for Infertility Related Distress
Status: UNKNOWN
Conditions: Infertility, Female|Distress, Emotional|Depressive Symptoms|Anxiety
Interventions: BEHAVIORAL: Mindful Self-Compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expert Consensus Statements for the Management of a Physiologically Difficult Airway Using the Delphi Method (PDADelphi)
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Intubation Complication|Hemodynamic Instability|Critical Illness
Interventions: OTHER: Delphi procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Assessment of Probiotics in Improving Sleep Indices
Status: RECRUITING
Conditions: Insomnia
Interventions: DIETARY_SUPPLEMENT: PS150|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation
Status: UNKNOWN
Conditions: Opioid-Induced Constipation
Interventions: DRUG: Naloxone HCl PR tablets|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial
Status: RECRUITING
Conditions: Glaucoma, Open-Angle
Interventions: DRUG: Nicotinomide|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dietary Intervention Increasing Omega-3 Intake
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: voucher for ordering foods (ONLY omega-3 rich foods)|OTHER: voucher for ordering foods in general (any type of foods)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of SEROQUEL in Selective Serotonin Reuptake Inhibitors (SSRI)-Resistant Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Quetiapine fumarate (Seroquel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Marrow-Derived Mesenchymal Stem Cell Treatment for Severe Patients With Coronavirus Disease 2019 (COVID-19)
Status: UNKNOWN
Conditions: Coronavirus Disease 2019 (COVID-19)
Interventions: BIOLOGICAL: BM-MSCs|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase IB/II Clinical Study of SHR-A2009 for Injection in Combination With Other Antitumor Therapies in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: SHR-A2009 for injection ； Almonertinib Mesilate Tablets|DRUG: SHR-A2009 for injection；Adebrelimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1% Metformin Gel-coated Implants and Osteointegration and Crestal Marginal Bone Loss
Status: NOT_YET_RECRUITING
Conditions: Osteointegration
Interventions: OTHER: Metformin gel coated implants|OTHER: uncoated hydrophilic dental implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG (Glycosaminoglycan) Levels in Aldurazyme® Treated Patients
Status: COMPLETED
Conditions: Mucopolysaccharidosis I|Hurler's Syndrome|Hurler-Scheie Syndrome|Scheie's Syndrome
Interventions: DRUG: laronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyadic Approach To Active Living and Eating Healthy: The DATE Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Dyadic health behaviour change intervention|BEHAVIORAL: Dyadic nutrition counselling intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Efficacy of Anti-Nicotine Immunotherapy
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BIOLOGICAL: NIC002 in Aluminum hydroxide (Alum)|BIOLOGICAL: Placebo Vaccine - Aluminum hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter, Double-blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Sildenafil on the As-Needed Efficacy of Viagra in Men With Erectile Dysfunction and Type 2 Diabetes
Status: COMPLETED
Conditions: Erectile Dysfunction|Diabetes Mellitus, Type 2
Interventions: DRUG: sildenafil|DRUG: placebo|DRUG: sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety
Status: RECRUITING
Conditions: Sleep Disturbance
Interventions: DRUG: normal Saline|DRUG: Esketamine|DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Peritoneal Lavage on Surgery-induced Positive Peritoneal Cytology in Gastric Cancer Patients
Status: COMPLETED
Conditions: Gastric Adenocarcinoma|Gastric Cancer
Interventions: PROCEDURE: pre-gastrectomy peritoneal washing cytology|PROCEDURE: post-gastrectomy peritoneal washing cytology|PROCEDURE: post-lavage peritoneal washing cytology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing a Dyadic Intervention for Sexually Transmitted Infection (STI)/HIV Prevention in Youth
Status: ACTIVE_NOT_RECRUITING
Conditions: Exposure to Sexually Transmissible Disorder (Event)
Interventions: BEHAVIORAL: Intervention|BEHAVIORAL: Individual evidence-based STI/HIV prevention intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fingers Hook Technique to Facilitate Nasotracheal Intubation
Status: COMPLETED
Conditions: Nasotracheal Intubation
Interventions: PROCEDURE: Conventional Jaw thrust Group|PROCEDURE: Fingers hook Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Airway Limitation Study: Study In Primary Care Centers Of Chronic Bronchitis In Long-Term Cigarette Smokers Of At Least 40 Years Of Age With Symptoms Of Cough And Shortness Of Breath
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Non-interventional study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clobetasol Propionate Spray Versus Vehicle Spray for the Management of Moderate to Severe Plaque Psoriasis of the Scalp
Status: COMPLETED
Conditions: Scalp Psoriasis
Interventions: DRUG: clobetasol propionate spray 0.05%|DRUG: Vehicle spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fixed Dose Rate Gemcitabine and Cisplatin Followed by Chemoradiation for Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: gemcitabine, cisplatin, capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Postoperative Catheterization
Status: COMPLETED
Conditions: Urinary Retention|Urinary Incontinence|Pelvic Organ Prolapse|Urinary Tract Infections
Interventions: OTHER: Post-void residual free voiding trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Dose-escalation Study of Fractionated 177Lu-PSMA-617 for Progressive Metastatic CRPC
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617|DRUG: 68Ga-PSMA-HBED-CC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Humanized CD19 CAR-T Cells Therapy for Patients With Relapsed and/or Refractory B-cell ALL and B-cell NHL
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Non-hodgkin Lymphoma,B Cell
Interventions: DRUG: Humanized CD19 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: tDCS Associated to Blindsight Rehabilitation for the Treatment of Homonymous Hemianopsia
Status: WITHDRAWN
Conditions: Hemianopsia
Interventions: OTHER: Blindsight Training associated to tDCS|OTHER: Blindsight Training alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Effects of Low-dose Naltrexone in ME/CFS
Status: WITHDRAWN
Conditions: Fatigue Syndrome, Chronic
Interventions: DRUG: Naltrexone HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Multicentre, Cohort Study of Screening and Preventive Intervention for Latent Tuberculosis Infection in Children
Status: UNKNOWN
Conditions: Children LTBI
Interventions: DRUG: INH、RFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of CM355 in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematoma
Interventions: DRUG: CM355
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Light Therapy in Hematology - The PHOTO-TREAT Study
Status: RECRUITING
Conditions: Leukemia, Myeloid, Acute|Lymphoma
Interventions: DEVICE: Phototherapy system CareMin650TM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Romidepsin and Parsaclisib for the Treatment of Relapsed or Refractory T-Cell Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Anaplastic Large Cell Lymphoma|Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Transformed Mycosis Fungoides|Refractory Anaplastic Large Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Transformed Mycosis Fungoides|T-Cell Non-Hodgkin Lymphoma
Interventions: DRUG: Parsaclisib|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Biodegradable Biliary Stents for the Treatment of Benign Biliary Strictures.
Status: COMPLETED
Conditions: Biliary Stricture|Biliary Tract Diseases|Bile Duct Stricture|Bile Duct Injury|Stents|Obstructive Jaundice
Interventions: DEVICE: Percutaneous placement of biodegradable biliary stents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Intermediate Cervical Plexus Block in Thyroid Surgery
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: local anesthetic|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Pain Control for Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: PROCEDURE: Transverse Abdominal Plan (TAP)|PROCEDURE: standard post op pain control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK
Status: RECRUITING
Conditions: Wet Age-related Macular Degeneration
Interventions: DRUG: Tarcocimab tedromer|DRUG: Tabirafusp tedromer|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy
Status: NOT_YET_RECRUITING
Conditions: Obstructive Hypertrophic Cardiomyopathy
Interventions: DRUG: HRS-1893
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advapro Coronary Stent System in Coronary Artery Diseased Patients.
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|De Novo Stenosis Lesion|Coronary Stent Implantation
Interventions: DEVICE: AdvaPro Sirolimus Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peptide Vaccination Against PD-L1 and PD-L2 in Relapsed Follicular Lymphoma
Status: COMPLETED
Conditions: Follicular Lymphoma
Interventions: BIOLOGICAL: PD-L2 peptide|BIOLOGICAL: PD-L2 and PD-L1 peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Combined With R-CHOP(R2-CHOP) in Newly Diagnosed Double-expressor Diffuse Large B-Cell Lymphoma Patients
Status: COMPLETED
Conditions: Double Expressor Lymphoma
Interventions: DRUG: Lenalidomide combined with R-CHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing
Status: ACTIVE_NOT_RECRUITING
Conditions: Tachycardia, Ventricular|Arrhythmia, Ventricular
Interventions: DEVICE: mCRM Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expiratory Muscle Training in Stroke
Status: COMPLETED
Conditions: Stroke|Mastication Disorder|Temporomandibular Disorders|Dysphagia|Stomatognathic Diseases
Interventions: OTHER: Expiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block in Children Undergoing Ostomy Surgery
Status: TERMINATED
Conditions: Anesthesia|Ostomy
Interventions: PROCEDURE: Transversus Abdominis Plane Block|PROCEDURE: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Mechanisms Underlying Nicotine and Alcohol Combinations
Status: COMPLETED
Conditions: Focus: Effects of Nicotine and Alcohol on Brain Circuits
Interventions: DRUG: Nicotine + Alcohol|DRUG: Placebo Nicotine + Alcohol|DRUG: Nicotine + Placebo Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability and Pharmacokinetics of CDD-2101 in Health Volunteers
Status: COMPLETED
Conditions: Constipation - Functional
Interventions: DRUG: CDD-2101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on Reparixin in Adult Patients With ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome, Adult
Interventions: DRUG: Reparixin 600mg|OTHER: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics
Status: WITHDRAWN
Conditions: Alzheimer Dementia|Posttraumatic Stress Disorder|Traumatic Brain Injury
Interventions: DEVICE: MRI|DEVICE: PET|DEVICE: 18F-Florbetapir|DEVICE: Radioligand 18F-AV-1451
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Hypnosis Combined With Tdcs on Pain Perception and Cortical Excitability in Fibromyalgia
Status: UNKNOWN
Conditions: Transcranial Direct Current Stimulation|Hypnosis|Fibromyalgia
Interventions: DEVICE: Active Tracranial Direct Current Stimulation|OTHER: Hypnotic analgesia suggestion|BEHAVIORAL: Rest|OTHER: Active tDCS + Hypnotic analgesia suggestion|OTHER: Sham tDCS + Hypnotic analgesia suggestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Evaluating the Pharmacokinetic Interaction Between AD-2071 and AD-2072
Status: COMPLETED
Conditions: Hyperlipidemias|Hypertension
Interventions: DRUG: AD-2071 10/20mg|DRUG: AD-2072 80/5mg|DRUG: AD-2071 10/20mg + AD2072 80/5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery
Status: COMPLETED
Conditions: Conscious Sedation
Interventions: DRUG: Dexmedetomidine Injection|DRUG: Placebo oral capsule|DRUG: Pregabalin Oral Capsule|DRUG: topical anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Double Versus Single Pledget Nasal Anesthesia for Transnasal Endoscopy
Status: UNKNOWN
Conditions: Anesthesia|Epistaxis
Interventions: DEVICE: Double pledget nasal anesthesia (DPNA)|DEVICE: Single pledget nasal anesthesia (SPNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Gastro Intestinal Bleeding|Blood Clot
Interventions: DRUG: Omeprazole 20 mg Oral Tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of a Calcium Channel Blocker to Prevent Premature Luteinizing Hormone Surges in Infertility Patients
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: Nimodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botanical Supplement Muscle Function and Lean Body Mass
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: CS16-003 Full dose|DIETARY_SUPPLEMENT: CS16-003 Half dose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Gut Microbiome and Sorafenib Maintenance Therapy in FLT3-ITD Positive AML After Allo-HSCT
Status: RECRUITING
Conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Sorafenib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving Pulmonary Function Following Radiation Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|RADIATION: Standard fractionation|RADIATION: Stereotactic Body Radiation Therapy (SBRT)|PROCEDURE: Four Dimensional Computed Tomographic Imaging (4DCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Fludarabine Phosphate|DRUG: Mesna|DRUG: Cyclophosphamide|RADIATION: Total nodal irradiation|BIOLOGICAL: T Cell-Depleted Hematopoietic Stem Cell Transplantation|PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|BIOLOGICAL: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Quality of Preoperative Information Obtained Through Preanestes@s, a Web Based Application
Status: COMPLETED
Conditions: Mobile Applications|Internet-Based Intervention|Preoperative Period
Interventions: OTHER: Quality of preoperative information register|OTHER: Suitability of information contained in the informed consent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Low Flow Anesthesia in Children Undergoing Strabismus Surgery
Status: NOT_YET_RECRUITING
Conditions: Low Flow Anesthesia|Sevoflurane|Strabismus|Emergence Delirium
Interventions: DRUG: Sevoflurane; In our study, the effects of sevoflurane in different FGFs administered in children undergoing strabismus surgery on EA and anesthetic agent consumption will be investigated.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Relapsed Pediatric ALL|Refractory Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: pCAR-19B cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACTHAR for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: ACTHAR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Reactogenicity and Immunogenicity of the VACCINE RNA MCTI CIMATEC HDT (HDT-301) Vaccine Against COVID-19
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: Cohort 1 VACCINE RNA MCTI CIMATEC HDT (HDT-301) vaccine|BIOLOGICAL: Cohort 2 RNA VACCINE MCTI CIMATEC HDT(HDT-301) vaccine|BIOLOGICAL: Cohort 3 VACCINE RNA MCTI CIMATEC HDT(HDT-301) vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Complete Versus Selective HepaticVascular Clamping in Hepatectomy
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Pringle's Maneuver|PROCEDURE: Hemihepatic vascular Clamping|PROCEDURE: Portal vein occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of tPA in Intra-abdominal Abscesses
Status: TERMINATED
Conditions: Abscess
Interventions: DRUG: Tissue Plasminogen Activator|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Enhanced Palliative Care in MDS and AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: OTHER: Enhanced Haematology Palliative Care ("Fast-track") Group|OTHER: Conventional Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Determine the Effect of Bi-Ventricular Pacing on Cardiac Hemodynamics After Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: Ethicon TPW32 60 cm (pacing wires x 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Nivolumab for Relapsed or Residual Haematological Malignancies After Allogeneic Stem Cell Transplantation
Status: UNKNOWN
Conditions: Haematological Malignancy
Interventions: DRUG: Nivolumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Moderate to Severe Glabellar Lines (BMI2006)
Status: COMPLETED
Conditions: Glabellar Lines
Interventions: BIOLOGICAL: BMI2006|BIOLOGICAL: BOTOX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Anesthetic Technique For ERCP
Status: COMPLETED
Conditions: Anesthesia; Adverse Effect
Interventions: PROCEDURE: Monitored Anesthesia Care|PROCEDURE: General Anesthesia|PROCEDURE: Induction Without Neuromuscular Blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparision Of The Effectiveness Of Physiotherapy Methods
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: PROCEDURE: ROM exercises, stretching, positioning, gait training|PROCEDURE: by two physiotherapist under the supervision of a doctor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Dietary Restrictions and Ketogenic Diet on Mitochondrial Function and Gut Microbiota in Subjects With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Ketogenic diet|OTHER: Caloric restriction diet|OTHER: Intermittent fasting 16/8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Near Infrared Light for the Treatment of Painful Peripheral Neuropathy
Status: TERMINATED
Conditions: Peripheral Neuropathy
Interventions: DEVICE: MIRE|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NSAIDs for Pain After Ankle Fracture Surgery
Status: WITHDRAWN
Conditions: Closed Fracture of Ankle
Interventions: DRUG: Naproxen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD
Status: RECRUITING
Conditions: Treatment Resistant Depression
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of RAdiofrequency Versus HAL- RAR DOppler in Hemorrhoidal Pathology
Status: RECRUITING
Conditions: Hemorrhoids
Interventions: DEVICE: Radiofrequency|DEVICE: Arterial ligation then recto-anal repair with Doppler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioactive Compounds in Watermelon Modulating Oxidative Stress and Inflammation in Elders
Status: COMPLETED
Conditions: Arterial Stiffness|Inflammation
Interventions: DIETARY_SUPPLEMENT: 100% watermelon juice|OTHER: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION