pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Tolerability Study of QLS-101 in Adolescents With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP)
Status: COMPLETED
Conditions: Sturge-Weber Syndrome|Glaucoma|Ocular Hypertension
Interventions: DRUG: QLS-101 ophthalmic solution, 2.0 %
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Rehabilitation Intervention for Amnestic Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Memory Support System|BEHAVIORAL: Computer Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Neck and Upper Limb Pain Using BurstDR (De Ridder) Stimulation
Status: UNKNOWN
Conditions: Neck Pain|Upper Limb Pain
Interventions: DEVICE: Spinal Cord Stimulation (SCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Auto-Adjustable MOBIDERM® Autofit NIGHT-time Compression Armsleeve in the Upper Limb LYMphedema in Maintenance Phase
Status: RECRUITING
Conditions: Lymphedema of Upper Arm
Interventions: DEVICE: Control group : Day-time compression sleeve|DEVICE: Intervention group : Day-time compression sleeve and Night-time MOBIDERM® Autofit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Aerobic Exercise on Serum Brain Natriuretic Peptide and C- Reactive Protein in Cardiovascular Disease
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: OTHER: Aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Investigate the Efficacy and Safety of GL2702 GLARS-NF1tablet and Harnal-D - Tablet in BPH Patients With LUTS
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Tamsulosin HCL 0.4mg|DRUG: Tamsulosin HCL 0.2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3
Status: TERMINATED
Conditions: Oxidative Stress|Endothelial Dysfunction
Interventions: DRUG: valsartan (ARB)|DRUG: ramipril (ACE inhibitor)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Serum Bupivacaine Level|Periarticular Block|Total Knee Arthroplasty
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: LEAP a New Overground Body Weight Support Robot: Usability Trial
Status: COMPLETED
Conditions: Spinal Cord Injuries|Cerebral Palsy|Parkinson Disease|Multiple Sclerosis|Stroke|People With Impaired Lower Extremity Function
Interventions: DEVICE: Therapist LEAP session feedback|DEVICE: Participant LEAP session feedback|DEVICE: LEAP risk control validation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Chemotherapy, Interferon Alfa, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant interferon alfa|DRUG: cisplatin|DRUG: dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Role of the Microbiome in the Response to Dietary Fibers Intake During Intermediate Fasting
Status: RECRUITING
Conditions: Dietary Fibers|Intermediate Fasting
Interventions: DIETARY_SUPPLEMENT: dietary fibers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Gentle Synchronized Negative Pressure in Helping Babies Breathe
Status: RECRUITING
Conditions: Respiratory Distress Syndrome|TTN|RDS of Prematurity|Respiratory Distress, Newborn
Interventions: DEVICE: NeoVest
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Nitrous Oxide as a Putative Novel Dual-Mechanism Treatment for Bipolar Disorder
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Nitrous Oxide|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recto Colonic Endoscopic Mucosal Resection and Polypectomy Under Clopidogrel
Status: COMPLETED
Conditions: Polyps
Interventions: PROCEDURE: Colonic polypectomy or endoscopic mucosal resection (EMR).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Diet on the Microbiome-Immune-Brain Axis in Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: 8 week predominantly plant-based New Nordic LPF-diet program|BEHAVIORAL: maintenance of the predominantly plant-based New Nordic LPF-diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Describe the Efficacy of Diphereline Following Conservative Surgery in Deep Infiltrating Endometriosis (DIE) Patients Over a Period of 24 Months
Status: COMPLETED
Conditions: Deep Infiltrating Endometriosis (DIE)
Interventions: DRUG: Triptorelin Acetate 3.75mg intramuscular injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Pulmonary Rehabilitation on Respiratory, and Cardiovascular Functional Capacity in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: pulmonary rehabilitation|OTHER: Education and self-management for COPD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 92/5000 Preoperative Efficacy of Traumeel Versus Dexamethasone in the Control of Pain, Swelling and Trismus
Status: UNKNOWN
Conditions: Molar, Third|Surgery
Interventions: DRUG: Dexamethasone|DRUG: Traumeel S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Benefit of RUCONEST® in Subjects Who Experience ADRs Related to IVIG Infusions
Status: COMPLETED
Conditions: CVI - Common Variable Immunodeficiency
Interventions: BIOLOGICAL: C1-esterase inhibitor [recombinant] (C1-INH-R)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Meningococcal Vaccine, Menactra® in Healthy Subjects in India
Status: COMPLETED
Conditions: Meningococcal Infection|Meningitis
Interventions: BIOLOGICAL: Meningococcal Polysaccharide Diphtheria Toxoid Conjugate (Menactra®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Triptolide Wilfordii in New Onset HIV-1 Infection
Status: COMPLETED
Conditions: HIV-infection/AIDS
Interventions: DRUG: Triptolide Wilfordii|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pilot Community-based Multi-domain Program Older Adults at Risk of Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Decline|Cognitive Impairment, Mild
Interventions: BEHAVIORAL: Multi-domain intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cryoablation or External-Beam Radiation Therapy in Treating Patients With Painful Bone Metastases
Status: TERMINATED
Conditions: Kidney Cancer|Melanoma (Skin)|Metastatic Cancer|Pain|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: PROCEDURE: cryosurgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Hyperfractionated Radiotherapy or Radiochemotherapy in Locally Advanced Rectal Cancer.
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: RADIATION: Hyperfractionated Radiochemotherapy|RADIATION: Hyperfractionated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glycaemic Markers in Persons With Type 2 Diabetes on Haemodialysis
Status: COMPLETED
Conditions: Diabetic Nephropathy Type 2|Type2 Diabetes
Interventions: DEVICE: Continuous glucose monitoring|DIAGNOSTIC_TEST: Glycaemic markers|RADIATION: Erythrocyte life span|DEVICE: Carbon monoxide (CO)-rebreathing method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility Trial of Narrative Exposure Therapy (NET) for Posttraumatic Stress Disorder (PTSD) During Pregnancy
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Narrative Exposure Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 1 Patients
Status: RECRUITING
Conditions: Spinal Muscular Atrophy
Interventions: GENETIC: GC101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of CDI and Recurrence With Fecal Microbiota Transplant Using Promicrobioma
Status: NOT_YET_RECRUITING
Conditions: Clostridium Difficile Infections
Interventions: OTHER: Fecal microbiota transplant (Promicrobioma)|DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An International, Multi-centre, Prospective, Non-controlled, Open, Single-group, 8-week Trial in Adolescent Subjects
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 80185 gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Characterization of Lipoprotein Apheresis Technologies for Individual Device Adaption (LOLIDA)
Status: RECRUITING
Conditions: Lipoproteinemia|Apheresis Related Complication|Cardiovascular Diseases
Interventions: DEVICE: Dextran sulfate absorption (LIPOSORBER® D - Kaneka Pharma Europe NV)|DEVICE: Lipid filtration (Octo Nova®, Diamed Medizintechnik)|DEVICE: Direct absorption of lipoproteins (DALI®; ADS 4008, Fresenius)|DEVICE: Therasorb (TheraSorb® - LDL adsorbers, Miltenyi Biotec)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Safety and Efficacy of Japanese Encephalitis Vaccine When Given With Measles Vaccine
Status: COMPLETED
Conditions: Encephalitis, Japanese B
Interventions: BIOLOGICAL: Live Japanese encephalitis vaccine SA 14-14-2 (LJEV)|BIOLOGICAL: Measles Vaccine (MV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Nanoparticles to Guide the Surgical Treatment of Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: (64Cu)-labeled PSMA-targeting particle tracer, or 64Cu-NOTA-PSMAi-PEG-Cy5.5-C' dots|DIAGNOSTIC_TEST: PET/MRI|OTHER: Blood and urine sampling|PROCEDURE: laparoscopic radical prostatectomy and bilateral pelvic LN dissection or a salvage lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carbetocin Versus Oxytocin and Hemodynamic Effects
Status: COMPLETED
Conditions: Effects of; Anesthesia, in Pregnancy
Interventions: DRUG: carbetocin 100 µg|DRUG: oxytocin 5 u|DRUG: placebo (NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Status: COMPLETED
Conditions: Back Pain Lower Back
Interventions: OTHER: Exercise program|DRUG: NSAID (Nonsteroidal anti-inflammatory drugs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Labial and Lingual Orthodontic Appliances on Root Resorption and Bone Height
Status: COMPLETED
Conditions: Crowding of Anterior Maxillary Teeth|Crowding of Anterior Mandibular Teeth
Interventions: PROCEDURE: Lingual brackets|PROCEDURE: Buccal brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Diuresis Timing (F+0 Vs F-15) on 99m Tc DTPA Renography for the Diagnosis of Suspected Obstructive Uropathy
Status: UNKNOWN
Conditions: Renal Scan in Suspected Obstructive Uropathy in Adult Hydronephrotic Patient
Interventions: DRUG: Furosemide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioavailability Study of Amlodipine Besylate/Atorvastatin Calcium Tablets 10/80 mg Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine besylate/Atorvastatin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) in Children and Adolescents With Epilepsy and Depression
Status: WITHDRAWN
Conditions: Depressive Disorder|Generalized Epilepsy
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Darbepoetin Alfa Treatment in Patients With Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Darbeopoetin|DRUG: Normal Saline (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ambrisentan in Limited Scleroderma Patients in Improving Blood Flow to Hands or Feet
Status: COMPLETED
Conditions: Ischemia
Interventions: DRUG: ambrisentan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates
Status: COMPLETED
Conditions: Sepsis|Infection|Bacteremia
Interventions: DRUG: Continuous infusion of vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-Unstuck:Interactive e-Learning Software for Parents to Support Executive Functioning and Behavior Regulation in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autistic Disorder
Interventions: OTHER: e-Unstuck|OTHER: Unstuck and On Target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Inhaled Aromatherapy on Nausea and Vomiting in Hematological Malignancies
Status: RECRUITING
Conditions: Hematological Malignancies
Interventions: COMBINATION_PRODUCT: "Blend of ginger and lemon essential oils", "Neutral oil"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Sciatic Nerve Gliding and Lower Extremity Dynamic Stretch on Hamstring Flexibility of Athletes
Status: COMPLETED
Conditions: Sports Physical Therapy
Interventions: OTHER: NEURAL GLIDING|OTHER: DYNAMIC STRETCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Psilocybin-Assisted Psychotherapy for Alcohol Use Disorder
Status: RECRUITING
Conditions: Alcohol Use Disorder|Alcoholism
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Sorafenib in Chemonaive Patients With Locally Advanced or Metastatic Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: sorafenib + erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREvention of VENous Thromboembolism In Hemorrhagic Stroke Patients
Status: TERMINATED
Conditions: Hemorrhagic Stroke|Venous Thromboembolism|Deep Venous Thrombosis
Interventions: DRUG: Enoxaparin|OTHER: Graduated compression stockings and/or intermittent pneumatic compression and/or early mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intraductal Meibomian Gland Probing Trial
Status: COMPLETED
Conditions: Meibomian Gland Dysfunction
Interventions: DRUG: Blephamide|DRUG: GenTeal PM Night-Time|PROCEDURE: Meibomian Gland Probing|PROCEDURE: Sham Meibomian Gland Probing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Isometric Hand Grip Training in Obstructive Sleep Apnea (OSA)
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Hypertension
Interventions: OTHER: Hand grip isometric contraction|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare FFR Measurement With a Non-Side-Hole Guide Catheter Vs. a Side-Hole Guide Catheter
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: FFR Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Gut Microbiota Association With ESBL-E Colonisation and Subsequent ESBL-E Infection
Status: UNKNOWN
Conditions: Extended Spectrum Beta-Lactamase Producing Bacteria Infection|Microbial Colonization|Critical Illness
Interventions: DIAGNOSTIC_TEST: ESBL-E fecal carriage screening according to routine care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of LANCONONE in Weight-bearing Joint Pain
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DIETARY_SUPPLEMENT: Lanconone®|DIETARY_SUPPLEMENT: Methyl crystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of an Early Antipsychotic Switch in Case of Poor Initial Response to the Treatment of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Olanzapine or amisulpride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Using Mobile Applications for Improving Oral Hygiene
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: BEHAVIORAL: Mobile phone application|BEHAVIORAL: Verbal oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Different Macronutrients on Ileal Brake Activation
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Casein|DIETARY_SUPPLEMENT: Sucrose|DIETARY_SUPPLEMENT: Sucrose|OTHER: Saline|DIETARY_SUPPLEMENT: Safflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation the Effect of AKK Formula on Intestinal Microbiota Regulation and Body Composition
Status: COMPLETED
Conditions: Body Weight Changes|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: AKK formula prebiotic sachet|DIETARY_SUPPLEMENT: Placebo sachet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Early PP Monitored by EIT in Patients With ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: EIT-guided mechanical ventilation strategy|PROCEDURE: Lung protective ventilation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEK Inhibitor PD-325901 To Treat Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: PD-0325901
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Laparoscopic Cholecystectomy on Risk of Metabolic Syndrome
Status: RECRUITING
Conditions: Cholelithiasis|Metabolic Syndrome
Interventions: PROCEDURE: Laparoscopic cholecystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance
Status: ACTIVE_NOT_RECRUITING
Conditions: Fall|Physical Performance|Fracture
Interventions: DIETARY_SUPPLEMENT: Cocoa extract|DIETARY_SUPPLEMENT: Cocoa extract placebo|DIETARY_SUPPLEMENT: Multivitamin|DIETARY_SUPPLEMENT: Multivitamin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma|Glioblastoma
Interventions: DRUG: ruxolitinib|RADIATION: radiation|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols (France)
Status: COMPLETED
Conditions: Mildly Hypercholesterolemic Subjects
Interventions: OTHER: 1-Low fat fermented dairy product enriched with plant sterol esters (0,8 g equivalent as free sterols) (test)|OTHER: 2-Low fat fermented dairy product (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Inulin-type Fructans-rich Vegetables, Obesity, Gut Microbiota
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Inulin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of E2027 in Participants With Dementia With Lewy Bodies (DLB) or Parkinson's Disease Dementia (PDD) With or Without Amyloid Copathology
Status: COMPLETED
Conditions: Lewy Body Disease|Parkinson Disease
Interventions: DRUG: E2027
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: SUN13834|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Different Modified POEM for Achalasia
Status: RECRUITING
Conditions: Esophageal Achalasia
Interventions: PROCEDURE: conventional myotomy|PROCEDURE: short myotomy|PROCEDURE: full-thickness myotomy|PROCEDURE: tailored myotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vardenafil ODT Versus Placebo in Males With Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Vardenafil ODT (STAXYN, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TEDDY: Spores of Bacillus Clausii in Acute Diarrhoea in Children
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Spores of Bacillus Clausii Probiotic Strain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy in Subjects With HPV-6 Associated Aerodigestive Precancerous Lesions and Malignancies
Status: COMPLETED
Conditions: Aerodigestive Precancerous Lesions and Malignancies
Interventions: BIOLOGICAL: INO-3106, INO-9012
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeted Assessment in High-Risk paTients With dIAbetes to ideNtify Undiagnosed Heart Failure
Status: RECRUITING
Conditions: Heart Failure|Diabetes Mellitus|Type 1 Diabetes|Type 2 Diabetes|Cardiovascular Diseases
Interventions: DIAGNOSTIC_TEST: NT-proBNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Antidepressant Effects of Ayahuasca: a Randomized Placebo Controlled Trial in Treatment Resistant Depression
Status: COMPLETED
Conditions: Major Depression
Interventions: DRUG: Ayahuasca|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo
Status: COMPLETED
Conditions: HIV/AIDS|Antiretroviral Therapy|Pregnancy Outcomes|HIV-exposed Infants
Interventions: OTHER: Continuous quality improvement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of Fibrinogen Concentrate (Human) (FCH) to Control Bleeding During Complex Cardiovascular Surgery
Status: COMPLETED
Conditions: Surgical Blood Loss|Postoperative Blood Loss
Interventions: BIOLOGICAL: Fibrinogen Concentrate (Human) (FCH)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Qualities of the Positron Emission Tomography Coupled to the Scanner (PET / CT) in the Assessment of Response to Non-Hodgkin's Lymphoma Therapy in Children and Adolescents
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma
Interventions: DEVICE: PET / CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: GRADE-SRM: Genomic Risk Assessment and Decisional Evaluation for Small Renal Masses
Status: COMPLETED
Conditions: Small Renal Mass|Kidney Tumor
Interventions: PROCEDURE: Small Renal Mass Biopsy|OTHER: No Small Renal Mass Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase II Study of All-Trans Retinoic Acid (ATRA) and Cemiplimab in Patients With Advanced Leiomyosarcoma
Status: NOT_YET_RECRUITING
Conditions: Leiomyosarcoma|Sarcoma
Interventions: DRUG: all-trans retinoic acid|DRUG: Cemiplimab|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Topical Haemoglobin Spray in Pressure Ulcer
Status: COMPLETED
Conditions: Pressure Ulcer|Wound Heal
Interventions: OTHER: Topical haemoglobin wound care spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Diagnostic Value of DWI-MRI for Detection of Peritoneal Metastases in High-risk Pancreatic Ductal Adenocarcinoma.
Status: RECRUITING
Conditions: Pancreas Cancer, Duct Cell Adenocarcinoma|Pancreas Adenocarcinoma|Peritoneal Metastases|Peritoneal Carcinomatosis
Interventions: DIAGNOSTIC_TEST: Whole-body diffusion-weighted magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Assess the Safety and Efficacy of Expanded Allogenic Adipose-derived Stem Cells (eASCs) (Cx601), for Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease.
Status: COMPLETED
Conditions: Crohn's Disease|Anal Fistula
Interventions: DRUG: Cx601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy on Local Anesthesia and Safety of 2% Lidocaine HCl With Different Epinephrine Concentration in Patients Undergoing Surgical Extraction of Impacted Lower Third Molars
Status: COMPLETED
Conditions: Third Molar
Interventions: DRUG: 2% lidocaine HCl with epinephrine 1:200,000|DRUG: 2% lidocaine HCl with epinephrine 1:80,000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epileptiform Activity During REM Sleep in Alzheimer's Disease
Status: UNKNOWN
Conditions: Alzheimer Disease, Early Onset
Interventions: DIAGNOSTIC_TEST: Overnight polysomnography|DIAGNOSTIC_TEST: blood sample|DIAGNOSTIC_TEST: high-resolution MRI scan|BEHAVIORAL: neuropsychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CBT-I for Veterans With TBI
Status: COMPLETED
Conditions: Insomnia|Traumatic Brain Injury
Interventions: BEHAVIORAL: Cognitive-Behavioral Therapy for Insomnia|BEHAVIORAL: Sleep Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preliminary Study on the Clinical Effect of Recombinant Human Brain Natriuretic Peptide on Sepsis Complicated With Heart Failure
Status: UNKNOWN
Conditions: Sepsis
Interventions: DRUG: Recombinant human brain natriuretic peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SI-B001 Combined With Osimertinib Mesylate Tablets in the Treatment of Recurrent Metastatic Non-small Cell Lung Cancer.
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: SI-B001|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Diagnosis and Therapy in LDLT Patients With High-risk Hepatocellular Carcinoma
Status: RECRUITING
Conditions: High Risk of Recurrence
Interventions: DRUG: Lenvatinib 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cereset for Caregivers
Status: WITHDRAWN
Conditions: Glioma
Interventions: DEVICE: Cereset Research Wearable|PROCEDURE: Stress management therapy|OTHER: Questionnaire administration|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Effectiveness of 2-dose Live Attenuated Varicella Vaccine
Status: UNKNOWN
Conditions: Varicella
Interventions: BIOLOGICAL: 2 doses with an 3 months interval|BIOLOGICAL: A second dose with an 1 year interval|BIOLOGICAL: A second dose with an 3 year interval|BIOLOGICAL: A second dose with an 5 year interval|BIOLOGICAL: 1 dose Varicella vaccine and 1 dose MMR given at the same time|BIOLOGICAL: 1 dose MMR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Laparoscopic Splenectomy on the Immune Function for Cirrhosis Patients
Status: RECRUITING
Conditions: Cirrhosis, Liver|Splenectomy; Status
Interventions: PROCEDURE: Laparoscopic splenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Supplements and Performance During Visual Field Testing (B3 Vitamin)
Status: COMPLETED
Conditions: Visual Field Defect, Peripheral|Glaucoma, Open-Angle
Interventions: DIETARY_SUPPLEMENT: Vitamin B3|DIETARY_SUPPLEMENT: Pyruvate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Randomized, Double-Blind, Placebo Controlled Study of NPC-02 in Patients With Zinc Deficiency
Status: COMPLETED
Conditions: Zinc Deficiency
Interventions: DRUG: NPC-02|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility.
Status: UNKNOWN
Conditions: Non-obstructive Azoospermia
Interventions: BIOLOGICAL: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarcosine or D-Serine Add-on Treatment for Chronic Schizophrenia
Status: COMPLETED
Conditions: Schizophrenias|Psychoses|Psychotic Disorders|Schizophrenic Disorders
Interventions: DRUG: Sarcosine and D-serine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Tolerance of B-Back® on the Burnout Syndrome
Status: COMPLETED
Conditions: Efficacy and Tolerance of B-Back® on the Burnout Syndrome
Interventions: DIETARY_SUPPLEMENT: Dietary supplement : B-Back® (α-casozepine, taurine, eleutherococcus senticosus, Extramel)|DIETARY_SUPPLEMENT: B-Back® placebo (without active compounds)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Phase 1 Study of IXAZOMIB in Adult Patients With Advanced Nonhematologic Malignancies
Status: COMPLETED
Conditions: Advanced Non-hematologic Malignancies
Interventions: DRUG: IXAZOMIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Additive Effect of Cognitive Behavioral Treatment (CBT) to Conventional Weight Loss Intervention Program for Young Adults With Intellectual Disabilities
Status: UNKNOWN
Conditions: Overweight|Obesity|Learning Disability
Interventions: OTHER: Nutritional intervention and physical activity|OTHER: Nutritional intervention, physical activity and behavioral treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Characterize the Cardiac Phenotype of Individuals With Friedreich's Ataxia (CARFA Study)
Status: COMPLETED
Conditions: Friedreich's Ataxia
Interventions: PROCEDURE: Cardiac magnetic resonance imaging (CMR)|PROCEDURE: Exercise-stress test|PROCEDURE: Echocardiography (ECHO)|PROCEDURE: Cardiac-related blood studies
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: C11-Sodium Acetate PET/CT Imaging for Metastatic Disease in Intermediate-to-high Risk Prostate Adenocarcinoma
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: C11-Sodium Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rapamycin Coated Balloon Dilation Catheter for Arteriovenous Fistula
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: PROCEDURE: Rapamycin drug balloon angioplasty|PROCEDURE: Paclitaxel drug balloon angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combivent® HFA-propelled Compared to CFC-propelled Metered Dose Inhaler in Patients With COPD (Chronic Obstructive Pulmonary Disease)
Status: TERMINATED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Combivent® HFA inhalation aerosol|DRUG: Combivent® CFC inhalation aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of AS902330 (rhFGF-18) Administered Intra-articularly in Patients With Knee Primary Osteoarthritis Who Are Candidates for Total Knee Replacement
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DRUG: AS902330|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short to Long Effects of Whole Body Cryostimulation on Insulin Sensitivity Among Overweight
Status: UNKNOWN
Conditions: Cryotherapy|Training|Overweight|Insulin
Interventions: OTHER: whole body cryostimulation treatment|OTHER: Connection WBC treatment and HIIT training|OTHER: Control Group|OTHER: HIIT training group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of Morphine on Loading-dose Ticagrelor in Patients With ST-segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: DRUG: Morphine|DRUG: metoclopramide|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use of Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia: A Prospective Observational Study
Status: COMPLETED
Conditions: Hypotension|Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions: OTHER: Observation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)
Status: COMPLETED
Conditions: Well-differentiated Non-functional NET of Thoracic Origin|Well-differentiated Non-functional NET of Gastrointestinal Origin|Well-differentiated Non-functional NET of Pancreatic Origin|Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma
Interventions: DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C-Raven, a Virtual Tobacco Cessation Intervention in the Community
Status: NOT_YET_RECRUITING
Conditions: Tobacco Dependence
Interventions: BEHAVIORAL: C-Raven Virtual Tobacco Cessation Counseling|DRUG: Nicotine Replacement Product|OTHER: Community Health Worker|OTHER: Lung Cancer Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect Of Occupational Therapy On Sensory-Based Feeding Problems
Status: UNKNOWN
Conditions: Feeding Disorder|Autism Spectrum Disorder|Sensory Integration Disorder (Disorder)
Interventions: OTHER: Family Training|OTHER: Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sea Buckthorn Oil and Lutein on Eye Health
Status: UNKNOWN
Conditions: Risk Factors for Age Related Macular Degeneration
Interventions: DIETARY_SUPPLEMENT: Sea buckthorn oil & lutein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dietary Intervention and Exercise Training (DIET) in Moderate to Severe Chronic Kidney Disease
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: BEHAVIORAL: low-impact aerobic exercise|DIETARY_SUPPLEMENT: low-calorie (low-fat) diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Patients With Methicillin-Resistant Staphylococcus Aureus Hospital-Acquired Pneumonia Treated With Linezolid or Vancomycin
Status: COMPLETED
Conditions: Methicillin-Resistant Staphylococcus Aureus (MRSA)|Hospital-Acquired Pneumonia
Interventions: DRUG: Linezolid|DRUG: Vancomycin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Urinary Nerve Growth Factor (NGF), Prostaglandin E2 (PGE2)and Adenosine Triphosphate (ATP): Potential Biomarkers in Overactive Bladder Patients
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: Oxybutinin, Fesoterodine, Solifenacin, Propiverin, Trospium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: New Antibiotic to Treat Patients With Community-acquired Pneumonia Due to a Specific Bacteria (S. Pneumoniae Pneumonia)
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal|Community Acquired Infections|Gram-positive Bacterial Infections
Interventions: DRUG: Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study With GFT505 (80mg) in Patients Presenting With Impaired Glucose Tolerance and Abdominal Obesity.
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Abdominal Obesity
Interventions: DRUG: GFT505 80mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observation of the Efficacy of BAd Regimen in the Treatment of Relapsed and Refractory Multiple Myeloma
Status: UNKNOWN
Conditions: Bendamustine|Multiple Myeloma
Interventions: DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Web-based Tailored Self-management Program
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Web-based Health Planner on diet and exercise|BEHAVIORAL: Non-tailored booklet on exercise and diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum
Status: COMPLETED
Conditions: Adenocarcinoma of Rectum
Interventions: DRUG: Short Course Adjuvent Chemotherapy|DRUG: Long Course Adjuvant Chemotherapy|RADIATION: Short Course Radiotherapy|RADIATION: Long Course Radiotherapy|DRUG: Concurrent Chemotherapy|PROCEDURE: Initial Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sarcopenia and Outcomes of Neuroplasty in Lumbar Spinal Stenosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lumbar Spinal Stenosis|Neurogenic Claudication|Sarcopenia
Interventions: PROCEDURE: Neuroplasty with Racz catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial Evaluating SCB-219M in in Chemotherapy-induced Thrombocytopenia (CIT)
Status: RECRUITING
Conditions: Chemotherapy-induced Thrombocytopenia (CIT)
Interventions: BIOLOGICAL: Recombinant Human Tumor Necrosis Factor Receptor II -Fc-TPO Mimetic Peptide Fusion Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT