pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Device Study to Evaluate the Detection and Characterization of Middle Ear Fluid in Children
Status: UNKNOWN
Conditions: Otitis Media With Effusion|Middle Ear Effusion
Interventions: PROCEDURE: Myringotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
Status: RECRUITING
Conditions: Neoplasm, Colorectal|Cognitive Impairment|Cognitive Dysfunction|Cognitive Change|Chemo-brain|Chemo Fog|Chemotherapy Effect|Cognitive Decline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Time Needed to Perform Intermittent Catheterization in Adults With Spinal Cord Injuries
Status: COMPLETED
Conditions: Spinal Cord Injuries|Neurogenic Lower Urinary Tract Dysfunction
Interventions: DEVICE: HPC - SpeediCath ®|DEVICE: Non-HPC - Self-Cath ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: LUNAR-4: Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Pembrolizumab for Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: NOT_YET_RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DEVICE: NovoTTF-200T|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nebivolol Tablets 5 mg Relative to Nebilet Tablets 5 mg
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Nebivolol-Test product|DRUG: Nebivolol-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Enhancing Prolonged Exposure With Cannabidiol to Treat Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Stress Disorders, Post-Traumatic
Interventions: DRUG: Cannabidiol (CBD) oral solution|DRUG: Placebo|BEHAVIORAL: Massed Prolonged Exposure (mPE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Facilitated Antegrade Steering Technique in Chronic Total Occlusions (FAST-CTOs)
Status: COMPLETED
Conditions: Coronary Artery Chronic Total Occlusion
Interventions: DEVICE: Recanalization of a coronary chronic total occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma Recurrent|Neuroblastoma
Interventions: COMBINATION_PRODUCT: 177Lu-DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcatheter Closure Versus Surgery of Perimembranous Ventricular Septal Defects
Status: COMPLETED
Conditions: Ventricular Septal Defects
Interventions: DEVICE: Shanghai pmVSD occluder|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of V0111 Cream on Open Cracked Heel in Diabetic Patients With Polyneuropathy.
Status: COMPLETED
Conditions: Open Cracked Heel in Diabetic Patients With Polyneuropathy
Interventions: DEVICE: Tested product : V0111 cream|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minocycline for Helicobacter Pylori Rescue Treatment
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: BQT|DRUG: PBM4M4|DRUG: PBM3M3|DRUG: PBM2M4|DRUG: PBM2M3
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gait Profile Score in Children With Cerebral Palsy (CP): Influence of the CP Type, Treatment With Botulinum Injection and Multilevel Surgery
Status: RECRUITING
Conditions: Cerebral Palsy|Gait Disorders in Children
Interventions: OTHER: Gait Profile Score|OTHER: Gait Visual Score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Evaluate the Efficacy and Safety of Different Doses of LEO 138559 in Adults With Moderate-to-severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: LEO 138559|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy Beat Accupunch (HBA) Exercise Program for Community Older Adults
Status: COMPLETED
Conditions: Perceived Health Status|Sleep Quality
Interventions: OTHER: Healthy Beat Accupunch (HBA) exercise program|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation
Status: NOT_YET_RECRUITING
Conditions: Respiratory Failure|Re-intubation Rate
Interventions: DEVICE: high flow nasal cannula|DEVICE: non invasive positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate the Change in Facial Pain Threshold During Auricular Acupuncture in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: PROCEDURE: AURICULAR ACUPUNCTURE|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mucolytic Effectiveness of Tacholiquine ® in Chronic Bronchitis
Status: COMPLETED
Conditions: Bronchitis, Chronic|Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tacholiquine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Hypofractionated IMRT Boost Versus Conventional IMRT Boost for Localized High Risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: Hypofractionated IMRT Radiation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations
Status: WITHDRAWN
Conditions: SARS-CoV2 Infection|SARS-CoV-2 Acute Respiratory Disease|Myeloma|Leukemia|Lymphoma|Immune Thrombocytopenia|Thrombotic Thrombocytopenic Purpura (TTP)
Interventions: BIOLOGICAL: BMS-986414|BIOLOGICAL: BMS-986413
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Age on the Median Effective Dose (ED50) of Intranasal Dexmedetomidine for Rescue Sedation Following Failed Sedation With Oral Chloral Hydrate During Magnetic Resonance Imaging
Status: COMPLETED
Conditions: Aged|Drug|Dose-Response Relationship
Interventions: DRUG: intranasal dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma|MGMT-Unmethylated Glioblastoma
Interventions: DRUG: Microtubule-Targeted Agent BAL101553|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm
Interventions: DRUG: NPX267
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer
Status: RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: mFOLFOX6, Atezolizumab and Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leading Advancements in the Uptake of Newborn Community Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Breastfeeding, Exclusive|Immunization; Infection|Growth; Stunting, Nutritional
Interventions: BEHAVIORAL: Newborn Health Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older
Status: TERMINATED
Conditions: Respiratory Syncytial Viruses|Respiratory Tract Diseases
Interventions: BIOLOGICAL: RSV Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Interprofessional Preoperative Geriatric Assessment for Older Arthroplasty Patients With Multimorbidity
Status: NOT_YET_RECRUITING
Conditions: Multimorbidity|Knee Arthrosis|Hip Arthrosis
Interventions: OTHER: Preoperative geriatric assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study to Assess Palonosetron Versus Ondansetron as Rescue Medication in Subjects That Develop Postoperative Nausea and Vomiting (PONV) in the Postanesthesia Care Unit (PACU)
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ondansetron|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: E-cigarettes for Harm Reduction Among Smokers With Serious Mental Illness
Status: RECRUITING
Conditions: Cigarette Smoking
Interventions: OTHER: E-cigarette (EC)|OTHER: Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Harm-Reduction Counseling|BEHAVIORAL: Ecological Momentary Intervention (EMI) Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Low-dose Transdermal Therapeutic System (TTS)-Fentanyl D-Trans in Taiwan Participants With Cancer Pain
Status: COMPLETED
Conditions: Cancer, Pain
Interventions: DRUG: Transdermal Therapeutic System (TTS)-Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Ketorolac Tromethamine Oral Drops Versus Naproxen For Moderate to Severe Back Pain Treatment
Status: COMPLETED
Conditions: Back Pain
Interventions: DRUG: Ketorolac Tromethamine|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and HIPEC
Status: NOT_YET_RECRUITING
Conditions: Inflammation|Cancer
Interventions: DRUG: Dexmedetomidine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First Mobilization Protocol for Total Knee Arthroplasty Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Arthroplasty
Interventions: OTHER: First mobilization protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System (PROMUS™ Element™) for the Treatment of a Single De Novo Coronary Artery Lesion
Status: UNKNOWN
Conditions: Atherosclerosis|Coronary Artery Disease
Interventions: DEVICE: PROMUS Element Coronary Stent System|DEVICE: TAXUS Liberté Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Individually Tailored Training Prescriptions in Cancer Patients: The TOP Study
Status: COMPLETED
Conditions: Cancer
Interventions: BEHAVIORAL: Standard endurance training|BEHAVIORAL: Polarized endurance training|BEHAVIORAL: Standard resistance training|BEHAVIORAL: Daily undulating periodization resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: VALOR: The Talent Thoracic Stent Graft System Clinical Study
Status: COMPLETED
Conditions: Thoracic Aortic Aneurysms
Interventions: DEVICE: Talent Thoracic Stent Graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Developed Perioperative Rehabilitation Pathway Following Lumbar Arthrodesis
Status: ACTIVE_NOT_RECRUITING
Conditions: Physical Disability|Low Back Pain, Recurrent|Surgery
Interventions: BEHAVIORAL: Rehabilitation with a biopsychosocial focus|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Tachosil as Dural Sealant Compared to Standard Treatment
Status: COMPLETED
Conditions: Subjects Scheduled for Supra-/Infratentorial Craniotomy
Interventions: PROCEDURE: Craniotomy supra- or infratentorial, dural closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of a Melanoma Vaccine (GVAX) With or Without Cyclophosphamide in Patients With Surgically Resected Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: BIOLOGICAL: melanoma GVAX|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Research Study Comparing Insulin Degludec to Insulin Detemir, Together With Insulin Aspart, in Pregnant Women With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin degludec|DRUG: Insulin Aspart|DRUG: Insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Decision Aids in Clinical Encounters
Status: COMPLETED
Conditions: Diabetes, Depression, Cardiovascular Disease,Hypercholesterolemia, Osteoporosis
Interventions: OTHER: Active Implementation of ShareEBM Toolkit|OTHER: Passive Dissemination of Share EBM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Implementation of Supportive Sling Device in Adults Post-stroke for Prevention of Shoulder Complications
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: DEVICE: Evaluate the effects of the EO31 shoulder sling in adults post-stoke
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Additive Hemostatic Efficacy of EndoClot After EMR or ESD in the Gastrointestinal Tract
Status: NOT_YET_RECRUITING
Conditions: Colonic Polyp|Colonic Neoplasms|Colonic Dysplasia
Interventions: PROCEDURE: EndoClot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sleep Intervention During Acute Lung Injury
Status: COMPLETED
Conditions: Critical Illness|Sleep|Acute Lung Injury|Acute Respiratory Distress Syndrome
Interventions: DRUG: Dexmedetomidine|DRUG: Midazolam and Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Marginal Bone Loss Around Mandibular Implant-retaining Overdentures and Implant Supported Fixed Hybrid Prosthesis
Status: ENROLLING_BY_INVITATION
Conditions: Bone Loss in Jaw|Dental Implant Failure Nos|Dental Implant Failed
Interventions: RADIATION: Peri-apical radiographs on the implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EF5 in Measuring Tumor Hypoxia in Patients With Stage I-III Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IA Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma|Stage IIIA Non-Small Cell Lung Cancer|Stage IIIB Non-Small Cell Lung Cancer
Interventions: DRUG: EF5|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Therapeutic Conventional Surgery|OTHER: Tissue Oxygen Measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Vadastuximab Talirine (SGN-CD33A; 33A) in Combination With Azacitidine in Patients With Previously Untreated Higher Risk MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: vadastuximab talirine|DRUG: Azacitidine|DRUG: Placebo (for 33A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of DEB-TACE Combined With Surufatinib and Camrelizumab in the Treatment of Inoperable or Metastatic ICC
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: COMBINATION_PRODUCT: DEB-TACE combined with Surufatinib and Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of King Vision Video Laryngoscope to McGrath MAC Video Laryngoscope for Nasal Intubation
Status: UNKNOWN
Conditions: Nasal Intubation
Interventions: DEVICE: King Vision video laryngoscope|DEVICE: McGrath MAC video laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
Status: ACTIVE_NOT_RECRUITING
Conditions: Pharmacokinetics|Safety Issues|Bleeding
Interventions: COMBINATION_PRODUCT: IPM Ring-105|COMBINATION_PRODUCT: IPM Ring-106
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: BRITEPath, Component 3 of iCHART (Integrated Care to Help At-Risk Teens)
Status: COMPLETED
Conditions: Depression|Suicidal Ideation
Interventions: BEHAVIORAL: BRITEPath
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Protective Effect of Pentoxifylline on Acute Kidney Injury
Status: UNKNOWN
Conditions: Pentoxifylline|Acute Kidney Injury
Interventions: DRUG: Pentoxifylline 400Mg Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety, Tolerability and Efficacy of MEDI8968 in Subjects With Moderate to Severe Hidradenitis Suppurativa
Status: TERMINATED
Conditions: Hidradenitis Suppurativa
Interventions: BIOLOGICAL: MEDI8968|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Quality Perception on Music in New Cochlear Implanted Subjects Using or Not a Fine Structure Strategy
Status: COMPLETED
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: DEVICE: FineHearing strategy or HDCIS strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effectiveness Prolift+M Versus Conventional Vaginal Prolapse Surgery
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse|Cystocele|Rectocele|Uterine Prolapse
Interventions: PROCEDURE: Prolift + M|PROCEDURE: conventional vaginal prolapse surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The BURAN Study of Buparlisib in Patients With Recurrent or Metastatic HNSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: Buparlisib & Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laryngeal Mask Airway (LMA®) and Tracheal Tube in Modified Radical Mastectomy on Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: LMA®|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Evaluate the Treatment Effect of an Anti-Infective Agent for Different Kinds of Infections (0826-052)
Status: COMPLETED
Conditions: Infection|Pneumonia|Urinary Tract Infection
Interventions: DRUG: MK0826, ertapenem sodium / Duration of Treatment: 14 Days
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great Toenail.
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: PD P 506 A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Status: COMPLETED
Conditions: Cataract|Lens Opacity|Presbyopia
Interventions: DEVICE: IOL implantation experimental|DEVICE: IOL implantation comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Extended Release Stimulant Medication in Treating Preschool Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Sequence 1: XR-MAS then placebo|DRUG: Sequence 2 Placebo then XR-MAS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.
Status: TERMINATED
Conditions: Charcot-Marie-Tooth Disease
Interventions: DRUG: FLX-787-ODT (orally disintegrating tablet)|DRUG: Placebo ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Efficacy and Safety of LAG525 in Combination With Spartalizumab, or With Spartalizumab and Carboplatin, or With Carboplatin, in Patients With Advanced Triple-negative Breast Cancer
Status: COMPLETED
Conditions: Triple-negative Breast Cancer
Interventions: DRUG: LAG525|DRUG: PDR001|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 5% Aqueous Propolis in Salivary and Dental Plaque pH in Children
Status: COMPLETED
Conditions: Child|Saliva|Dental Plaque
Interventions: OTHER: Effect of aqueous propolis gums in salivary and dental plaque pH in children|OTHER: Effect of placebo gums in salivary and dental plaque pH in children
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Acinar Cell Carcinoma|Pancreatic Adenocarcinoma|Pancreatic Adenosquamous Carcinoma|Pancreatic Carcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Squamous Cell Carcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Nab paclitaxel|DRUG: Gemcitabine|DRUG: Cisplatin|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Computed Tomography|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Transesophageal Echocardiography Along With an Orogastric Tube Improve the Image Quality Intraoperatively?
Status: COMPLETED
Conditions: TEE Image Quality
Interventions: PROCEDURE: Suction orogastric tube which is attached to TEE probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extracorporeal CO2 Removal for Acute Decompensation of COPD
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: ECCO2R|DEVICE: NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Physical Training and the Omega 3 Consumption on Attention Deficit Hyperactivity Disorder in Children
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Omega 3|OTHER: Physical Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aerosol Generation in Dental Clinics
Status: RECRUITING
Conditions: Risk Reduction|Occupational Exposure|Dentist-Patient Transmission
Interventions: OTHER: Chlorhexidine mouthwash and Povidone-Iodine|DEVICE: High volume evacuator|DEVICE: High volume evactuator and saliva ejector|DEVICE: Local Exhaust System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Deep Cervical Flexors Training On Forward Head Posture, Neck Pain and Functional Status
Status: COMPLETED
Conditions: Forward Head Posture|Neck Pain
Interventions: OTHER: Craniocervical flexion training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients
Status: TERMINATED
Conditions: Chronic Phase-Chronic Myeloid Leukemia
Interventions: DRUG: Bosutinib 400 MG Monotherapy|DRUG: Bosutinib 400 MG + Atezolizumab 840 MG in 14 ML Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PAP for Children With DS and OSAS
Status: RECRUITING
Conditions: Down Syndrome|Obstructive Sleep Apnea
Interventions: BEHAVIORAL: Family-informed intervention|BEHAVIORAL: Standard Clinical Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer
Interventions: DRUG: AAA617|DRUG: Gonadotropin-releasing hormone (GnRH) analogues|DRUG: Gonadotropin-releasing hormone (GnRH) antagonists
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Tumor Treating Fields Treatment for Brain Cancer Patients With Skullremodeling Surgery (Neurosurgery)
Status: RECRUITING
Conditions: Recurrent Glioblastoma
Interventions: PROCEDURE: Skullremodeling surgery|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anlotinib in Patients With Metastatic Colorectal Cancer（mCRC）(ALTER0703)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Anlotinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultra Low Iodine Loaded Spectral CT Angiography (CTA)
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Renal Insufficiency
Interventions: DIAGNOSTIC_TEST: Half iodine Spectral CT|DIAGNOSTIC_TEST: Standard iodine conventional CT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Correlation of Genetic Variations With Clinical Response in Substance Use Disorder
Status: RECRUITING
Conditions: Substance Use Disorders|Substance Dependence
Interventions: DRUG: Quetiapine, olanzapine, mirtazapine, carbamazepine, sertraline, amitriptyline, chlorpromazine and risperidone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Lymphoplasmacytic Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Marginal Zone Lymphoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Ibrutinib|DRUG: Lenalidomide|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Three Endourological Procedures for the Management of Renal Calculi Regarding Acute Kidney Injury
Status: COMPLETED
Conditions: Renal Calculi|Renal Insufficiency
Interventions: PROCEDURE: PCNL|PROCEDURE: mini-PCNL|PROCEDURE: RIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome
Status: NOT_YET_RECRUITING
Conditions: Hypoplastic Left Heart Syndrome
Interventions: PROCEDURE: Fetal Aortic Valvuloplasty Procedure|DEVICE: Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter|DEVICE: Trek RX and Mini Trek RX Coronary Dilatation Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of HAIC Using Cisplatin,Leucovorin and 5-Fluorouracil
Status: UNKNOWN
Conditions: HepatoCellular Carcinoma
Interventions: DRUG: 5-Fu, oxaliplatin , leucovorin|DRUG: 5-Fu, oxaliplatin , leucovorin|DRUG: 5-Fu, oxaliplatin , leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Noscapine HCl (CB3304 ) in Patients With Relapsed or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Refractory Multiple Myeloma
Interventions: DRUG: Noscapine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Ruxolitinib (INCB018424) in Patients With Myelofibrosis and Post Polycythemia Vera/Essential Thrombocythemia Myelofibrosis
Status: COMPLETED
Conditions: Myelofibrosis|Polycythemia Vera|Thrombocytosis
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: DRUG: Brentuximab Vedotin|DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Informing the Adaptation of a CHW Model to Facilitate Lung Cancer Screening for the Chinese Community
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer Screening|Current or Past Cigarette Smoker
Interventions: BEHAVIORAL: Surveys|BEHAVIORAL: Navigation|BEHAVIORAL: Focus groups|BEHAVIORAL: In-depth interviews
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Haemodynamical Optimization During Brain Surgery
Status: RECRUITING
Conditions: Brain Edema
Interventions: PROCEDURE: Hemodynamic management based on invasive fluid responsiveness parameters|PROCEDURE: Hemodynamic management based on noninvasive cardiac output and SVV measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, TAPA-Pulsed Dendritic Cell Therapy and Imiquimod in Progressive and/or Refractory Solid Malignancies
Status: TERMINATED
Conditions: Progressive Solid Malignancies|Refractory Solid Malignancies|Cancer
Interventions: BIOLOGICAL: TAPA-pulsed DC vaccine|DRUG: Cyclophosphamide Pill|DRUG: Imiquimod Topical Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors|Ovarian Cancer|Gastric Cancer|Colo-rectal Cancer
Interventions: DRUG: NC410
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial About the Contribution of Manual Lymph Drainage in Complex Physical Therapy for Patients With Lymphoedema Secondary to Mastectomy
Status: COMPLETED
Conditions: Lymphoedema
Interventions: OTHER: Compression Bandaging|OTHER: Manual Lymph Drainage (MLD) and Compression Bandaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Two Different Root Canal Sealers on Postobturation Pain and Clinical and Radiographical Outcome After Two-year Follow-up
Status: COMPLETED
Conditions: Asymptomatic Vital Mandibular Molar Teeth
Interventions: OTHER: MTA Fillapex root canal sealer|OTHER: AH Plus root canal sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D for Chronic Sinusitis
Status: COMPLETED
Conditions: Chronic Sinusitis
Interventions: DIETARY_SUPPLEMENT: vitamin D placebo|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mandibular Reconstruction Preplanning (ViPMR)
Status: RECRUITING
Conditions: Oral Cavity Cancer|Oral Cancer
Interventions: PROCEDURE: Virtual Surgical Planning (VSP)|PROCEDURE: Free-Hand Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Healthy Participants
Interventions: DRUG: Semaglutide B, 1.34 mg/mL|DRUG: Semaglutide B, 0.68 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rate of Canine Retraction and Pain Perception Following Micro-osteoperforation- a Split Mouth Clinical Study
Status: NOT_YET_RECRUITING
Conditions: Pain|Rate of Canine Retraction
Interventions: OTHER: micro osteoperforation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Smiley Face Shaped Rod Technique Versus Instrumented Posteriolateral Fusion in Treatment of Isthmic Lumbar Spondylolisthesis
Status: UNKNOWN
Conditions: Isthmic Spondylolisthesis
Interventions: PROCEDURE: smiley face shape rod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 3-way Crossover Clinical Investigation to Assess the Performance of Two Different Sized Polyurethane Condoms Versus a Latex Condom in Healthy Monogamous Couples.
Status: RECRUITING
Conditions: Contraception
Interventions: DEVICE: Polyurethane (PU) male condom-Test condom 1|DEVICE: Polyurethane (PU) male condom-Test condom 2|DEVICE: Natural Rubber Latex (NRL) male condom- Control condom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Goal-directed Therapy in Endovascular Coiling of Cerebral Aneurysm Patients
Status: COMPLETED
Conditions: Cerebral Aneurysm
Interventions: DEVICE: Flotrac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Ischaemic Conditioning in Endovascular Recanalization for Proximal Anterior Circulation Occlusion Study
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: PROCEDURE: RIPC Remote Ischaemic Pre-Conditioning|OTHER: Sham Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Patients With Knee Prostheses Treated With Noninvasive Neuromodulation
Status: RECRUITING
Conditions: Knee Prosthesis
Interventions: DEVICE: Non-invasive Neuromodulation|DEVICE: Placebo Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Resistance in Non-alcoholic Fatty Liver Disease
Status: TERMINATED
Conditions: Fatty Liver|Insulin Resistance
Interventions: DRUG: rosiglitazone|DRUG: fenofibrate|DRUG: placebo for rosiglitazone|DRUG: placebo for fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Test How Healthy Women Tolerate Different Doses of BI 1819479
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1819479|DRUG: BI matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Patient-Centered Intervention to Improve Opioid Safety
Status: COMPLETED
Conditions: Opioid Safety|Prescription Opioid Misuse|Chronic Pain
Interventions: BEHAVIORAL: ISOP Intervention with the Nurse Care Manager
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroplasticity With Daily Use of a Sensorimotor Priming Vibration System to Improve Hand Function After Stroke
Status: COMPLETED
Conditions: Stroke|Physical Disability
Interventions: OTHER: peripheral vibration stimulation|BEHAVIORAL: therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of IV Infusion of Lidocaine Compared to IV Infusion of Dexmedetomidine on Proinflammatory Cytokines
Status: COMPLETED
Conditions: Inflammatory Response
Interventions: DRUG: dexmedetomidine infusion|DRUG: lidocaine infusion|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Single Center Study for the Treatment of Moderate to Severe Allergic Conjunctivitis (EBI-005-AC-1)
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Active Comparator EBI-005 5 mg/mL|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Motivational Interviewing and Mindfulness-Oriented Recovery Enhancement
Status: RECRUITING
Conditions: Polysubstance Abuse|Opioid Use|Tobacco Use
Interventions: OTHER: MORE and MI and NRT|OTHER: MORE and No MI and NRT|OTHER: Support Group and MI and NRT|OTHER: Support Group and No MI and NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Human Gingivitis With Amnion-derived Cellular Cytokine Solution (ACCS)
Status: COMPLETED
Conditions: Gingivitis
Interventions: DRUG: 1X ACCS (Amnion-derived Cellular Cytokine Solution)|DRUG: Normal saline|DRUG: 0.3X ACCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Conservative Versus Aggressive Revascularization in Patients With Intermediate Lesions Undergoing Percutaneous Coronary Intervention With Angiography Guidance Alone
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: The aggressive group|PROCEDURE: The conservative group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation
Status: RECRUITING
Conditions: IBS|IBS - Irritable Bowel Syndrome
Interventions: DRUG: Tenapanor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Regucalcin Level and Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis b|Liver Fibrosis
Interventions: DIAGNOSTIC_TEST: Serum regucalcin level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Graphic Messages to Prevent E-Cigarette Use Among Black and Latino Adolescents
Status: COMPLETED
Conditions: Vaping
Interventions: BEHAVIORAL: Financial reward graphic message|BEHAVIORAL: Health reward graphic message|BEHAVIORAL: Self-efficacy graphic message|BEHAVIORAL: Social norms graphic message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PFI for Pain-Related Anxiety Among Hazardous Drinkers With Chronic Pain
Status: COMPLETED
Conditions: Alcohol Problem|Chronic Pain|Alcohol Abuse
Interventions: BEHAVIORAL: Personalized Feedback Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between Cognitive, Behavioral, and Cognitive-Behavioral Therapy for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Applied relaxation and self-control desensitization|OTHER: Cognitive therapy (CT)|BEHAVIORAL: Cognitive-Behavioral Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute T-Rex (Timing of Resistance Exercise) Study
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance|Glucose Intolerance|Sleep Disturbance|Overweight or Obesity|Insulin Sensitivity
Interventions: BEHAVIORAL: Resistance Exercise Timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adolescent Mental Health InSciEd Out
Status: COMPLETED
Conditions: Mental Disorders|Substance-Related Disorders|Social Stigma|Mental Health Wellness 1|Mental Health Impairment
Interventions: BEHAVIORAL: Curricular Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER