pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Endoscopic Ultrasound (EUS) Fine Needle Biopsy (FNB) Submucosal Nodule
Status: WITHDRAWN
Conditions: GI Lesions
Interventions: DEVICE: Pro Core Needle|DEVICE: medtronic Sharkcore Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: EXPAREL|DRUG: On-Q Pain Ball
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial Comparing Combination Treatment (Solifenacin Plus Mirabegron) With One Treatment Alone (Solifenacin)
Status: COMPLETED
Conditions: Urinary Bladder Diseases|Urinary Bladder Overactive|Urologic Diseases
Interventions: DRUG: mirabegron 25 mg|DRUG: mirabegron 50 mg|DRUG: solifenacin 5 mg|DRUG: solifenacin 10 mg|DRUG: mirabegron 25 mg matching placebo|DRUG: mirabegron 50 mg matching placebo|DRUG: solifenacin 5 mg matching placebo|DRUG: solifenacin 10 mg matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors
Status: ACTIVE_NOT_RECRUITING
Conditions: Haemophilia A Without Inhibitors|Haemophilia B Without Inhibitors
Interventions: DRUG: Concizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 20110165: Study to Evaluate the Effect of AMG 747 on Schizophrenia Negative Symptoms (Study 165)
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: AMG 747|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Versus Videoconference Communication for Remote Genetic Disclosure in the APOE4 Trial
Status: COMPLETED
Conditions: Alzheimer Disease|Genetic Predisposition to Disease
Interventions: OTHER: Two-way videoconference remote genetic counseling|OTHER: Telephone remote genetic counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Pharmacodynamic Effects and Predictive Biomarkers With Ruxolitinib in Operable Head and Neck Cancer
Status: WITHDRAWN
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia
Status: WITHDRAWN
Conditions: Relapsed or Refractory Acute Myeloid Leukemia|Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Interventions: DRUG: VS-4718
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of A2 Milk Versus Conventional Milk on Intestinal Health: a Proof-of-concept Study in IBS-patients
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: OTHER: A2 milk|OTHER: Conventional milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Improving Medication Adherence Among Underserved Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: REACH|BEHAVIORAL: Helpline and A1c results|BEHAVIORAL: REACH + FAMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-invasive Transcranial Focused Low-intensity Ultrasound Stimulation in Patients With Mild Lewy Body Dementia
Status: NOT_YET_RECRUITING
Conditions: Lewy Body Dementia
Interventions: DEVICE: Transcranial low intensity focused ultrasound stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
Status: RECRUITING
Conditions: Congenital Myotonic Dystrophy
Interventions: DRUG: Tideglusib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Explorative Phase II Study of Perioperative Treatment in Patients With Adenocarcinoma of the Gastroesophageal Junction or Stomach
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Adenocarcinoma of the Stomach
Interventions: DRUG: 5-FU, leucovorin, docetaxel, oxaliplatin (FLOT), trastuzumab|DRUG: Post-operative treatment trastuzumab mono therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Telbivudine in Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B|Roadmap Concept in Chronic Hepatitis B Treatment|24-week PCR Negativity of Telbivudine|PCR Negativity at 52 and 104 Week|HBeAg Seroconversion Rate at 52 and 104 Week
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Prevention of Postoperative Nausea and Vomiting Using Cesamet
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Nabilone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Correlation of Serum Level of Perampanel (PER) Level to Cerebrospinal Fluid (CSF) Levels of PER
Status: UNKNOWN
Conditions: Epilepsy|Seizures
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HER2 Expression of HER2 Affibody-based PET/CT to Predict Response in Bladder Cancer Patients Treated With ADC
Status: RECRUITING
Conditions: HER2 Positive or Suspicious Positive Tumors
Interventions: RADIATION: HER2 expression of PET imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Adverse Effect of Simvastatin Compare to Rosuvastatin in Systemic Lupus Erythematosus (SLE) Patients With Corticosteroid Therapy and High Low-Density Lipoprotein (LDL) Cholesterol Level
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|High LDL Cholesterol Level
Interventions: DRUG: Rosuvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Preoperative Duloxetine on the Occurance of Postoperative Delirium in Patients Undergoing Cancer Surgery.
Status: NOT_YET_RECRUITING
Conditions: Post Operative Delirium
Interventions: DRUG: Duloxetine 60 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Bioresorbable Implants for Scaffolding Obstructions in Randomized Bifurcations (BIFSORB) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Absorb|DEVICE: Desolve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2
Status: COMPLETED
Conditions: Alveolar Bone Preservation|Bone Graft
Interventions: DEVICE: Inject BMP|DEVICE: ExcelOS-inject
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling and Low-level Laser Therapy to Treat Myofascial Pain
Status: COMPLETED
Conditions: Myofascial Pain|Trigger Points
Interventions: OTHER: Dry Needling|DEVICE: Low-Level Laser Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis
Status: COMPLETED
Conditions: Metastatic Malignant Neoplasm to Brain
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPG 7909 Injection in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: DRUG: CPG 7909|DRUG: Chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cluster Randomized Trial of a Digital Quality Improvement Intervention on LDLCholesterol Control
Status: RECRUITING
Conditions: Cardiovascular Diseases|Atherosclerosis|Dyslipidemias
Interventions: BEHAVIORAL: Digitally-enabled Multifaceted Quality Improvement Intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Safety and Efficacy of a Compound Natural Health Product in Children With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: Compound Natural Health Product|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: British Randomised Controlled Trial of Atrioventricular (AV) and Interventricular (VV) Optimisation (BRAVO)
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: Non-invasive haemodynamic optimisation|OTHER: ECHO optimisation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine to Prevent Cough and Hemodynamic Changes in Tracheal Extubation
Status: UNKNOWN
Conditions: Lidocaine
Interventions: DRUG: Lidocaine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3% Normal Saline Nebulization Versus Steroid Nebulization in the Treatment of Bronchiolitis
Status: COMPLETED
Conditions: Acute Bronchiolitis
Interventions: DRUG: 3% normal saline|DRUG: steroid(beclomethasone dipropionate 400 μg/day) and salbutamol with 0.9% normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Pharmacokinetics, Pharmacodynamics and Tissue Concentrations of Epelsiban
Status: TERMINATED
Conditions: Embryo Transfer
Interventions: DRUG: Epelsiban|DRUG: Placebo|DRUG: Oxytocin|DRUG: Ortho-Cylcen (21)® tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Build-up Computed Assisted History Taking, Physical Examination and Diagnosis System of Emergency Patient Through Machine Learning (II)
Status: RECRUITING
Conditions: Internal Disease
Interventions: DIAGNOSTIC_TEST: Artificial intelligence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-
Status: RECRUITING
Conditions: Peritoneal Carcinomatosis|Gastric Cancer
Interventions: PROCEDURE: Staging laparoscopy|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Docetaxel|PROCEDURE: Radical surgery|PROCEDURE: PIPAC|DRUG: Adjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Complex Decongestive Physiotherapy on Sensory Parameters in Breast Cancer Related Lymphedema.
Status: UNKNOWN
Conditions: Lymphedema|Lymphedema of Upper Arm|Breast Cancer
Interventions: OTHER: Complex Decongestive Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety Evaluation of HCP1904-3 in Essential Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: HCP1904-3|DRUG: RLD2001-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-Administered Lidocaine Gel for Pain Management With First Trimester Surgical Abortion: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Pregnancy, Unwanted
Interventions: DRUG: vaginal 2% Xylocaine|DRUG: standard lidocaine paracervical block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Two Doses of Monovalent Inactivated Influenza Vaccine That is Adjuvanted With MF59C.1 (MF59) and Uses a Surface Antigen From a Potential Pandemic Virus Strain Candidate (H5N1) in Adult and Elderly Subjects Using Four Different Vaccination Schedules
Status: COMPLETED
Conditions: Pre-pandemic Influenza Vaccine
Interventions: BIOLOGICAL: Monovalent inactivated influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: REGN2810 (Anti-PD-1 Antibody), Platinum-based Doublet Chemotherapy, and Ipilimumab (Anti-CTLA-4 Antibody) Versus Pembrolizumab Monotherapy in Patients With Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: REGN2810/ipi|DRUG: REGN2810/chemo/ipi|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Acute Effects of Commercially Available Drinks on the Endothelial Function of Humans Following a High-fat Meal
Status: COMPLETED
Conditions: Endothelial Dysfunction
Interventions: OTHER: Water|OTHER: Red Wine|OTHER: Green Tea|OTHER: Orange Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Vitamin D Therapy on Glucose Homeostasis in Obese Adolescents
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Single-center Study on the Effect of Systemic/Selective Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With Components With Consolidation/Tumor Ratio Between 0.5-1
Status: NOT_YET_RECRUITING
Conditions: Progression|Postoperative Recovery
Interventions: OTHER: selective lymph node dissection|OTHER: Systemic Lymph Node Dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SINUS LIFT 100% Anorganic Bovine Bone vs. 50% Anorganic Bovine Bone + 50% Autologous Bone
Status: COMPLETED
Conditions: Maxillary Sinus|Dental Implants
Interventions: DEVICE: 50% AAB plus 50% autologous bone|DEVICE: 100% AAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Atorvastatin/Fenofibrate (LCP-AtorFen) Combination Therapy in Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: LCP-AtorFen|DRUG: atorvastatin|DRUG: fenofibrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Memantine Treatment for Improving Rehabilitation Outcomes and Preventing Depression in Older Adults
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Memantine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mechanical Power as a Predictor for Weaning in Chronic Obstructive Pulmonary Disease Patients :Prospective Cohort Study.
Status: NOT_YET_RECRUITING
Conditions: Mechanical Power
Interventions: OTHER: Chest ultrasound|OTHER: Calculation of Mechanical Power on the first day of intubation and before First trial of weaning:
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Eye-Cervical Re-education Versus Motor Imagery Therapy on Proprioception in Chronic Mechanical Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Neck Pain
Interventions: OTHER: eye cervical re-education|OTHER: motor imagery therapy|OTHER: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dry Needling Treatment in Myofascial Pain Syndrome
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial
Interventions: PROCEDURE: dry-needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Arm Motor Control on Bi and Uni ADLs
Status: TERMINATED
Conditions: Stroke|Peripheral Neuropathy|Spinal Cord Injuries|Cerebral Palsy
Interventions: DEVICE: Bilateral assessment robots (BiAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High-frequency Electrical Spinal Cord Stimulation Versus Electrical Spinal Cord Stimulation in the Treatment of Diabetic Peripheral Neuropathic Pain
Status: NOT_YET_RECRUITING
Conditions: Painful Diabetic Peripheral Neuropathy
Interventions: DEVICE: spinal cord stimulator|DEVICE: high frequency spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neubotulinum Toxin Injection in Cerivical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: Neuronox ® Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia Patients
Status: COMPLETED
Conditions: Anemia|Hemosiderosis
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Percussive Massage on Skeletal Muscle During Limb Immobilization
Status: RECRUITING
Conditions: Massage Therapy|Muscular Atrophy
Interventions: DEVICE: percussive massage|COMBINATION_PRODUCT: Leg Immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Aflibercept as Maintenance Therapy Following Induction With Aflibercept in Combination With XELOX, as First-Line Treatment for Metastatic Colorectal Cancer Patient
Status: TERMINATED
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Aflibercept AVE0005|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adolescent Transition To Adult Care for HIV-infected Adolescents in Kenya
Status: COMPLETED
Conditions: Adolescent Behavior|HIV|Transition|Adolescent Development|Disclosure
Interventions: BEHAVIORAL: Adolescent Transition Package
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chronic Dietary Exposure to Branched Chain Amino Acids
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus With Features of Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: branched chain amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cyclophosphamide and Fludarabine Followed By an Autologous Lymphocyte Infusion and Interleukin-2 in Treating Patients With Refractory or Recurrent Metastatic Melanoma
Status: TERMINATED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: therapeutic autologous lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Infusion Set Function: Quick-Set Teflon Catheter Versus Sure-T Steel Infusion Set Catheter
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Sure-T Steel Infusion Set Catheter|DEVICE: Quick-Set Teflon Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of NGGT006 in Refractory Hypercholesterolemia Patients
Status: NOT_YET_RECRUITING
Conditions: Refractory Hypercholesterolemia|Familial Hypercholesterolemia
Interventions: DRUG: NGGT006
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GORE TAG® Thoracic Endoprosthesis - 45 mm for the Treatment of Aneurysms of the Descending Thoracic Aorta
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracic
Interventions: DEVICE: GORE TAG® Thoracic Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: Placebo|DRUG: 0.15% Azelastine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistant Starch and Whey Protein on Energy Metabolism
Status: COMPLETED
Conditions: Weight Loss
Interventions: OTHER: waxy maize starch|OTHER: waxy maize starch and Whey Protein|OTHER: Resistant Starch|OTHER: resistant starch and whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Corneal Thickness Changes in Patient Undergoing Dry Eye Managment
Status: UNKNOWN
Conditions: Dry Eye Disease
Interventions: DRUG: Polyethylene Glycol 400 0.4%-Propylene Glycol 0.3%. and Dextran 0.1%Hypromellose 0.3%,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Stretching Exercises Applied to Diabetes Patients on Physiological Parameters and Compliance to Treatment: A Randomized Controlled Study
Status: NOT_YET_RECRUITING
Conditions: Individuals With Diabetes
Interventions: BEHAVIORAL: stretching exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Glutamine as Prophylaxis for Irinotecan Induced Diarrhea
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Glutamine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate
Status: COMPLETED
Conditions: Anesthesia|Transurethral Resection of Prostate Syndrome|Myocardial Infarction
Interventions: OTHER: general anesthesia or neuraxial anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination of Dental Bleaching Techniques, Randomized Clinical Trial
Status: COMPLETED
Conditions: Tooth Stain
Interventions: OTHER: Hydrogen Peroxide and Carbamide Peroxide|OTHER: Hydrogen Peroxide and Hydrogen Peroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-provisional Stenting vs Mini-Crush in Chronic Total Occlusions (CTO)
Status: COMPLETED
Conditions: Ischemic Heart Disease|Coronary Atherosclerosis|Coronary Artery Disease|Coronary Artery Stenosis
Interventions: PROCEDURE: T-provisional stenting|PROCEDURE: Mini-crush stenting|PROCEDURE: CTO coronary angioplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study About Acting of Adaptive Sport in Musculoskeletal, Cardiovascular System and the Quality of Life of Individuals With Spinal Cord Injury Through Biomedical Instrumentation
Status: UNKNOWN
Conditions: Adaptive Sport in Spinal Cord Injury
Interventions: OTHER: adapted canoeing, hadbike and conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ear Acupuncture for Pain Associated With Ambulatory Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Pain
Interventions: OTHER: Ear Acupuncture|DRUG: Standard Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of the Hepatitis A Virus Vaccine HAVpur in Healthy Young Children
Status: COMPLETED
Conditions: Hepatitis A
Interventions: BIOLOGICAL: HAVpur Junior|BIOLOGICAL: Havrix 720 Junior
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Feasibility Study of Chemo-radiotherapy to Treat Operable Oesophageal Cancer
Status: UNKNOWN
Conditions: Oesophageal Cancer
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: Radiotherapy|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ai Chi Method for Children With Asthma
Status: UNKNOWN
Conditions: Asthma|Child|Respiratory Disease|Hydrotherapy|Respiratory Tract Diseases|Respiratory Hypersensitivity|Respiration Disorders
Interventions: OTHER: Ai Chi|OTHER: Asthma education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at the Combination of Chemotherapy, Trastuzumab and RAD001 in HER2 Positive Breast Cancer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Efficacy and Safety of Lenalidomide in Patients With Mantle Cell NHL Who Have Relapsed or Progressed After Treatment With Bortezomib or Are Refractory to Bortezomib. The "EMERGE" Trial
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cangrelor in Comatose Survivors of OHCA Undergoing Primary PCI
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest|Acute Coronary Syndrome
Interventions: DRUG: Cangrelor 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Use, Effects and Side-effects of Second-generation Antipsychotics in a Naturalistic Setting
Status: COMPLETED
Conditions: Psychotic Disorders
Interventions: DRUG: Olanzapine|DRUG: Quetiapine|DRUG: Risperidone|DRUG: Ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sport Surgery Products Outcomes - A Post-market Follow-up
Status: RECRUITING
Conditions: Sport Surgery
Interventions: DEVICE: Orthopaedic surgeries (ankle)|DEVICE: Orthopaedic surgeries (shoulder)|DEVICE: Orthopaedic surgeries (knee)|DEVICE: Orthopaedic surgeries|DEVICE: Orthopaedic surgeries (foot)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Ultrasound To Increase Parental Bonding in Women With Substance Use Disorders
Status: UNKNOWN
Conditions: Substance Use Disorders|Pregnancy
Interventions: OTHER: 2 dimensional vs. 3 dimensional ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Learn How Different Amounts and Forms of the Study Medicine PF-07899895 Are Tolerated and Act in the Body of Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Participants
Interventions: DRUG: PF-07899895|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Viral Kinetics Study of Telbivudine and Entecavir in Adults With Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B|Chronic Hepatitis B
Interventions: DRUG: Entecavir|DRUG: Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes
Status: RECRUITING
Conditions: Lipodystrophy Acquired|Type1diabetes
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Letrozole + Palbociclib/Placebo in Metastatic Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: Palbociclib/placebo|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of YH25448(Lazertinib) as the First-line Treatment in Patients With EGFR Mutation Positive Locally Advanced or Metastatic NSCLC (LASER301)
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Lazertinib 240 mg/160 mg|DRUG: Gefitinib 250 mg|DRUG: Lazertinib-matching placebo 240 mg/160 mg|DRUG: Gefitinib-matching placebo 250 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Combinations of Long-acting β2-agonists (LABA) and Inhaled Glucocorticosteroid (ICS)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Locking Compression Plate Fixation Versus Revision- Prosthesis of Vancouver-B2, B3 and C Periprosthetic Femoral Fractures After Total Hip Replacement
Status: COMPLETED
Conditions: Periprosthetic Fractures
Interventions: PROCEDURE: Operation for Periprosthetic fractures of the hip with stem loosening
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of GAP-134 Administered Intravenously
Status: COMPLETED
Conditions: Arrhythmia
Interventions: DRUG: GAP-134
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
Status: UNKNOWN
Conditions: Osteo Arthritis Knee|Knee Osteoarthritis|Knee Pain Chronic|Knee Arthritis|Knee Disease|Knee Pain Swelling|Joint Diseases
Interventions: COMBINATION_PRODUCT: autologous adipose tissue transfer|COMBINATION_PRODUCT: PRP injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for the Treatment of Vulvodynia
Status: TERMINATED
Conditions: Vulvodynia|Vulvar Vestibulitis
Interventions: DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Branched Chain Aminoacid Supplementation in Patients With Liver Cirrhosis
Status: COMPLETED
Conditions: Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Branched-chain aminoacids|OTHER: High-fiber high protein diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Hepafast" in Non-alcoholic Fatty Liver Disease (NAFLD)
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease (NAFLD)|Obesity
Interventions: OTHER: Hepafast|OTHER: LOGI diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Second-look Endoscopy on Peptic Ulcer Rebleeding in Patients With Early Resumption of Antiplatelet Agents
Status: TERMINATED
Conditions: OGD|Gastric Ulcer Induced by Anti-platelet Agent|Duodenal Ulcer Induced by Anti-platelet Agent
Interventions: PROCEDURE: Second-look OGD|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Therapeutic Effects of Naohuan Dan and Idebenone in Treating Mild Cognitive Impairment With Kidney Deficiency and Phlegm Stasis
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Idebenone|DRUG: Naohuan Dan and Idebenone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanical Complications of Acute Myocardial Infarction
Status: COMPLETED
Conditions: Post-Infarction Heart Rupture|Post-Infarction Ventricular Septal Defect|Post-Infarction Mitral Papillary Muscle Rupture
Interventions: PROCEDURE: Surgery for mechanical complications of acute myocardial infarction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131).
Status: UNKNOWN
Conditions: Cholera
Interventions: BIOLOGICAL: Hillchol vaccine|BIOLOGICAL: Shanchol Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Respiratory Abnormalities
Status: UNKNOWN
Conditions: Respiratory Failure|Respiratory Arrest|Respiratory Distress Syndrome|Acute Respiratory Failure|Acute Respiratory Failure With Hypoxia|Acute Respiratory Failure With Hypercapnia|Acute Respiratory Failure Post Surgical|Acute Respiratory Failure Postprocedural|Acute Respiratory Failure Following Trauma and Surgery|Acute Respiratory Failure Requiring Reintubation|Acute Respiratory Failure Post Traumatic|Acute Respiratory Decompensation|Shock|Shock, Septic|Shock, Cardiogenic|Acute Cardiac Failure|Multi Organ Failure|Acute Kidney Failure
Interventions: OTHER: Observational retrospective cohort to describe data validity; and Data reliability; and Completeness of the data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Radiotherapy/ Oxaliplatin/ Capecitabine Treatment For Unresectable Locally-advanced Rectal Cancer
Status: COMPLETED
Conditions: Rectal Neoplasms
Interventions: DRUG: Oxaliplatin|DRUG: Capecitabine|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine Versus Propofol in Vitreoretinal Surgery
Status: COMPLETED
Conditions: Retinal Detachment
Interventions: DRUG: Dexmedetomidine infusion|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVD
Status: UNKNOWN
Conditions: Pulmonary Thromboembolisms|Pulmonary Embolism
Interventions: DRUG: Recombinant tissue plasminogen activator (rt-PA)|DRUG: Low Molecular Weight Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerveblocks for Persistent Pain After Breast Cancer Surgery
Status: UNKNOWN
Conditions: Pain|Neuropathic Pain|Breast Cancer
Interventions: DRUG: Bupivacaine|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Focal Thermal Therapy Acupoint OA Knee RCT
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Randomized Controlled Trial
Interventions: DEVICE: Thermal gun|OTHER: Heat pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluation With Scans and Pharyngometry of the Possible Changes in Upper Airway Geometry Induced by Using Different Mouthpieces.
Status: COMPLETED
Conditions: Influence of Mouthpiece Design on Upper Airway Geometry
Interventions: RADIATION: Magnetic Resonance imaging|OTHER: Pharyngometry|RADIATION: Computed Tomography scan|RADIATION: Cone Beam Computed Tomography scan|OTHER: Dental impressions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combination Therapy in Pulmonary Arterial Hypertension
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Bosentan|DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Ceramic-on-Ceramic Total Hip Replacement Versus Metal-on-Metal Hip Resurfacing in Young Active Patients
Status: COMPLETED
Conditions: Indications for a Total Hip Prosthesis
Interventions: DEVICE: ceramic-on-ceramic total hip replacement versus metal-on-metal hip resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Alpha-1 Antagonist, Stress and Relaxation on Anorectal Functions
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: Alfuzosin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Medial Branch Blocks vs. Intra-articular Injections: Randomized, Controlled Study
Status: COMPLETED
Conditions: Lumbar Facet Joint Pain|Low Back Pain
Interventions: PROCEDURE: Intra-articular injection|PROCEDURE: Medial branch block|PROCEDURE: Saline injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GSK1349572 Hepatic Impairment Study
Status: COMPLETED
Conditions: Healthy Subjects|Hepatic Impairment|Infection, Human Immunodeficiency Virus|HIV Infections
Interventions: DRUG: GSK1349572
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploratory Study of TAC-302 in Detrusor Underactivity Patients With Overactive Bladder.
Status: COMPLETED
Conditions: Detrusor Underactivity|Overactive Bladder
Interventions: DRUG: TAC-302|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self-determination Enhancement Group for Adults With Mild Intellectual Disability and Their Caregivers in Hong Kong
Status: UNKNOWN
Conditions: Intellectual Disability, Mild
Interventions: BEHAVIORAL: Self-determination Enhancement Group|BEHAVIORAL: Self-determination Enhancement Plus Group|BEHAVIORAL: Leisure activity group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cannabidiol on Reward- and Stress-related Neurocognitive Processes in Individuals With Opioid Use Disorder
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: DRUG: Cannabidiol 100 MG/ML [Epidiolex]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paired-Comparison Study Evaluating the Efficacy and Safety of E6201 Versus Vehicle for the Treatment of Plaque-Type Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: E6201 0.005%|DRUG: E6201 0.01%|DRUG: E6201 0.03%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Crossed Education in Relation to Muscle Mass in Patients Operated of Clavicular Fracture
Status: RECRUITING
Conditions: Clavicle Fracture
Interventions: OTHER: concentric-eccentric strength training|OTHER: eccentric strength training|OTHER: standard physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
Status: RECRUITING
Conditions: Metastatic Breast Cancer|End of Life
Interventions: BEHAVIORAL: Clinician Qualitative Interview
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Outcomes of Zirconia-reinforced Lithium Silicate Partial Coverage Crowns Compared to Lithium Disilicate Partial Coverage Crowns
Status: COMPLETED
Conditions: Partial Coverage Restoration
Interventions: OTHER: Vita Suprinity|OTHER: IPS e.max
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Brivaracetam in Subjects With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy, Focal
Interventions: OTHER: Placebo|DRUG: Brivaracetam|DRUG: Brivaracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access Study of Talimogene Laherparepvec for Treatment of Subjects With Unresected Stage IIIB-IVM1c Melanoma
Status: NO_LONGER_AVAILABLE
Conditions: Unresected Stage IIIB to IVM1c Melanoma
Interventions: DRUG: Talimogene Laherparepvec
Study Type: EXPANDED_ACCESS
Clinical trial: Safety Study of an Influenza Vaccine Against a Potential Pandemic Strain of Flu
Status: COMPLETED
Conditions: Influenza (Pandemic)
Interventions: BIOLOGICAL: pPML7789 with and without pPJV2012 administered by PMED
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Analgesic Techniques for Rib Fractures
Status: NOT_YET_RECRUITING
Conditions: Rib Fractures
Interventions: PROCEDURE: ESP block with catheter using ropivacaine (bolus followed by continuous infusion)|DRUG: Lidocaine bolus (1 mg/kg) and infusion starting at 1 mg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Assess the Pharmacokinetics, Safety, and Tolerability of ACT-129968 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ACT-129968 500 mg tablet|DRUG: ACT-129968 250 mg capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER