pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Reconstruction of the Medial Patellofemoral Ligament - A Randomised Controlled Trial Comparing Two Surgery Technics
Status: COMPLETED
Conditions: Knee Stability|Patella Luxation
Interventions: OTHER: Anchor fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate Drug-drug Interactions Between BR9006-1 and BR9006-2 in Healthy Male Volunteers.
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia (BPH)|Overactive Bladder
Interventions: DRUG: BR9006-1|DRUG: BR9006-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Feasibility to Derive Vaccine From Tumor Tissue in Patients With Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small-Cell Lung Carcinoma|Lung Cancer|Pulmonary Cancer
Interventions: BIOLOGICAL: HSPPC-96
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Blood Flow Restriction on Functional Mobility in Pre-frail Older Adults
Status: COMPLETED
Conditions: Frailty
Interventions: OTHER: Resistance exercise on the lower extremities|OTHER: Resistance exercise on the lower extremities with blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Perioperative Gabapentin on Postoperative Opioid Requirements
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Preoperative Gabapentin/Postoperative Placebo|DRUG: Preoperative Gabapentin/Postoperative Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS
Status: ACTIVE_NOT_RECRUITING
Conditions: Refractory Acute Myeloid Leukemia|Relapsed Acute Myelomonocytic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: CPX-351
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Icotinib With Intensity-modulated Radiotherapy in Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Icotinib|RADIATION: intensity-modulated radiotherapy|DRUG: Paclitaxel and Cisplatin|OTHER: Quality of life|GENETIC: Epidermal growth factor receptor status
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
Status: RECRUITING
Conditions: Congenital Heart Disease in Children|Hypoxia|Neurodevelopmental Disorders|Complex Congenital Heart Disease
Interventions: PROCEDURE: Single Arm|PROCEDURE: Neonatal Neurobehavioral Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Approved Drug to Study a New Indication for Seasonal Allergic Rhinitis in Patients With Asthma (0476-269)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Asthma, Bronchial
Interventions: DRUG: MK0476, montelukast sodium|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Metabolic, Immunological and Microbiological Characteristics of Obese Patients
Status: ENROLLING_BY_INVITATION
Conditions: Obesity
Interventions: DIAGNOSTIC_TEST: Determination of the level of interleukins in the blood, stool analysis for the intestinal microbiome, general clinical tests, glucose tolerance test, hormonal profile
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PXD101 and Bortezomib in Treating Patients With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Post-transplant Lymphoproliferative Disorder|Primary Central Nervous System Hodgkin Lymphoma|Primary Central Nervous System Non-Hodgkin Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Splenic Marginal Zone Lymphoma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Adult T-cell Leukemia/Lymphoma|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: DRUG: belinostat|DRUG: bortezomib|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Treatments in Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: PROCEDURE: laser photocoagulation|DRUG: eye drop bromfenac 0.09%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Pembrolizumab and Nab-paclitaxel in HER-2 Negative Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Pembrolizumab|DRUG: Nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strengthening Contraceptive Counseling in Pakistan
Status: WITHDRAWN
Conditions: Contraception
Interventions: OTHER: Routine care|OTHER: Package of contraceptive counseling interventions|OTHER: Expanded methods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Effects of Telmisartan and Valsartan on Neointima Volume in Diabetes
Status: COMPLETED
Conditions: Hypertension|Diabetes|Coronary Artery Disease
Interventions: DRUG: telmisartan|DRUG: valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Do Inflammatory Arthritis Inpatients Receiving Group Music Therapy Improve Pain Compared to Music Listening?
Status: COMPLETED
Conditions: Arthritis, Rheumatoid|Spondylarthropathies|Arthritis, Psoriatic|Inflammatory Arthritis
Interventions: OTHER: Music Therapy|OTHER: Music Listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
Status: TERMINATED
Conditions: Aneuploidy|Pregnancy|Miscarriage
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10 concomitant treatment|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Open Label Non-Interventional Evaluation of the Effect of Adjuvant Hormonal Treatment of Postmenopausal Women Wih Early Breast Cancer With Aromatase Inhibitors on Bone Mineral Density and Bone Fracture Rate in Daily Practice
Status: COMPLETED
Conditions: Breast Cancer|Osteoporosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Semi-quantitative Procalcitonin Assay to The Adequacy of Empirical Antibiotics and Mortality in Septic Patients
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: semi-quantitative procalcitonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-Incision Laparoscopic Cholecystectomy Versus Traditional Laparoscopic Cholecystectomy
Status: TERMINATED
Conditions: Biliary Dyskinesia|Gallstones|Cholecystitis|Cholelithiasis
Interventions: PROCEDURE: Single-Incision Laparoscopic Surgery cholecystectomy|PROCEDURE: Traditional Laparoscopic Cholecystectomy (TLC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With a Spinal Orthosis Compared to Equipment Group Training and a Control Group
Status: COMPLETED
Conditions: Osteoporosis|Vertebral Fracture|Back Pain|Elderly Women
Interventions: DEVICE: Spinal orthosis Spinomed|OTHER: Equipment training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Status: TERMINATED
Conditions: Healthy|Mild Cognitive Impairment|Alzheimer Disease
Interventions: DEVICE: real anodal transcranial direct current stimulation (tDCS)|DEVICE: sham transcranial direct current stimulation (tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Microbial Protease Supplementation on Postprandial Plasma Amino Acid Concentrations and Appetite
Status: COMPLETED
Conditions: Digestive Health|Gastrointestinal Health|Appetitive Behavior
Interventions: DIETARY_SUPPLEMENT: OPTIZIOME® P³ HYDROLYZER® - WHEY|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Food on the Bioavailability and Pharmacokinetic Profile of Itasetron After a Single Oral Dose in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Itasetron tablet|DRUG: Itasetron infusion|OTHER: high fat breakfast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of PF-06939926 for the Treatment of Duchenne Muscular Dystrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Duchenne Muscular Dystrophy
Interventions: GENETIC: PF-06939926|OTHER: Placebo|OTHER: Placebo|GENETIC: PF-06939926
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PhaseⅠFirst-in-Human Study of Hemay007 in Healthy Volunteers
Status: UNKNOWN
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: Hemay007|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Esmolol on Perioperative Stress Reaction
Status: NOT_YET_RECRUITING
Conditions: Esmolol|Stress Reaction|Airway Obstruction|Catecholamine; Overproduction
Interventions: DRUG: Esmolol|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety, Tolerability, PK and Food Effect of BEN8744.
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: BEN8744|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nebulized Ketamine to Intravenous Sub-Dissociative Dose Ketamine for Pain
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine via Intravenous|DRUG: Ketamine via BAN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Ketamine
Status: COMPLETED
Conditions: Hemorrhage|Healthy
Interventions: DRUG: Ketamine Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimal Protein Supplementation and Early Exercise In Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Nutritional Deficiency|Cachexia
Interventions: DIETARY_SUPPLEMENT: Optimal protein supplementation to achieve 80% protein adequacy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Radiation Therapy to Relieve Symptoms in Patients With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Fatigue|Lung Cancer|Nausea and Vomiting|Pain|Pulmonary Complications|Quality of Life
Interventions: PROCEDURE: fatigue assessment and management|PROCEDURE: nausea and vomiting therapy|PROCEDURE: pain therapy|PROCEDURE: quality-of-life assessment|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant and Adjuvant Tislelizumab for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Great Saphenous Vein Electrocoagulation
Status: UNKNOWN
Conditions: Venous Disease|Varicose Veins
Interventions: DEVICE: GSV Electrocoagulation|DEVICE: GSV Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing pOrtable MRI and TRUS-Fusion Prostate Biopsy to Assess aCcuracy of Prostate Cancer Detection
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Promaxo portable MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Copeptin: Disease Severity Indicator
Status: COMPLETED
Conditions: Lower Respiratory Tract and Lung Infections|Ventilator Lung|Bronchopneumonia|Bronchitis
Interventions: DIAGNOSTIC_TEST: Copeptin level measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term tDCS Tinnitus Treatment
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesic Effects of Bilateral External Oblique Intercostal Block in Laparoscopic Cholecystectomy Surgery
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative
Interventions: OTHER: Pain Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Test How Either a Capsule or a Tablet With NDec (Decitabine and Tetrahydrouridine) Works in the Body of Healthy People
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Decitabine-THU|DRUG: Decitabine-THU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Application Regimens for Viscosupplementation
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: viscosupplementation 1+1+1|DRUG: viscosupplementation 3 at once
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Site Infection and Antibiotic Use Study
Status: COMPLETED
Conditions: Surgical Site Infection|Breast Reconstruction|Antibiotic Use
Interventions: DRUG: Single pre-operative dose of intravenous antibiotics with intraoperative redosing|DRUG: One week of post-operative antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Status: COMPLETED
Conditions: Deep Caries|Pulp Exposure, Dental|Dental Caries
Interventions: PROCEDURE: Selective removal to soft dentin (SRSD)|PROCEDURE: Selective removal to firm dentine (SRFD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Making Healthy Decisions: A Trial Evaluating the "Your Move" Teen Pregnancy-prevention Intervention
Status: COMPLETED
Conditions: Pregnancy, Abdominal|Sexual Behavior|Sexually Transmitted Infection|Sexually Transmitted Diseases|Dietary Modification|Eating Behaviors
Interventions: BEHAVIORAL: Your Move|BEHAVIORAL: Eat Smart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Severe Acute Respiratory Syndrome
Interventions: DRUG: Unfractionated heparin|DRUG: Streptokinase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: US Cycle Control and Blood Pressure Study
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Gestodene/EE (FC Patch Low, BAY86-5016)|DRUG: Oral contraceptive (equivalent to the active treatment tablets of Levlite), 21-day blister SH D00593A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Decitabine and Talazoparib in Untreated AML and R/R AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Decitabine|DRUG: talazoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of an Inactivated SARS-CoV-2 Vaccine (CoronaVac) in Children and Adolescents
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Inactivated Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Status: RECRUITING
Conditions: Metastatic Uveal Melanoma|Cutaneous Melanoma|Colorectal Cancer|Other Solid Tumors
Interventions: DRUG: IDE196|DRUG: Binimetinib|DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) Compared to Placebo in Migraine Prevention
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Erenumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Smectite Effect As A Food Thickener On Gastroesophageal Reflux Disease In Neonates Using Combined Esophageal Multichannel Intraluminal Impedance
Status: COMPLETED
Conditions: Gastroesophageal Reflux in Neonates
Interventions: DRUG: Diosmectite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: KatGuide Method Versus Conventional Method at Insertion of Chest Tube
Status: COMPLETED
Conditions: Pneumothorax|Hydrothorax|Hemothorax|Empyema|Chylothorax
Interventions: DEVICE: KatGuide versus conventional method (forceps)|PROCEDURE: Chest tube insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Combination With TBI-1401(HF10) and Ipilimumab in Japanese Patients With Unresectable or Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma Stage III|Melanoma Stage IV
Interventions: BIOLOGICAL: TBI-1401(HF10)|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: e-GAB: Electronic Geriatric Assessment Bundle: Development of an Arabic Self-administered Android CGA Application
Status: COMPLETED
Conditions: Health Services for the Aged|Frailty|Cognitive Impairment|Depression|Disability Physical|Urinary Incontinence|Malnutrition
Interventions: DIAGNOSTIC_TEST: e-GAB|DIAGNOSTIC_TEST: standard physician performed CGA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)
Status: TERMINATED
Conditions: Pre-Eclampsia|Stage 1 Hypertension|Elevated Blood Pressure
Interventions: DRUG: Aspirin 81 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Analgesic Efficacy of Erector Spinae Plane Block for Laparoscopic Inguinal Hernia Repair
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: Erector Spina Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation.
Status: RECRUITING
Conditions: Excessive Gingival Display
Interventions: DIETARY_SUPPLEMENT: zinc gluconate 50 mg with phytase supplement 176mg (800FTU)|DIETARY_SUPPLEMENT: zinc gluconate 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Session of Active Video Game Promotes Post Exercise Hypotension in Middle-aged Hypertensive
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: AVideogame|DEVICE: SVideogame|DEVICE: EMIntensity|DEVICE: EISVideogame|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Does Cholecystectomy Increase the Esophageal Alkaline Reflux? Evaluation by Impedance-pH Technique
Status: COMPLETED
Conditions: Cholecystolithiasis|Cholecystectomy|Gastroesophageal Reflux
Interventions: PROCEDURE: impedance pH measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study in Healthy Subjects to Investigate Pharmacokinetics of AZD5423 When Administered in Different Ways
Status: COMPLETED
Conditions: Bioavailability and AUC
Interventions: DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423|DRUG: AZD5423
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- UCLA Portal R/R Influenza RCT 3
Status: COMPLETED
Conditions: Influenza|Respiratory Tract Infections
Interventions: BEHAVIORAL: Portal Reminders for Influenza Vaccination: Direct scheduling link|BEHAVIORAL: Portal Reminders for Influenza Vaccination: No direct scheduling link|BEHAVIORAL: Pre-Commitment Prompt|BEHAVIORAL: Pre-Appointment flu vaccine reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the Abuse Liability Potential of Cenobamate in Recreational Drug Users
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Alprazolam Placebo|DRUG: Cenobamate placebo|DRUG: Alprazolam|DRUG: Cenobamate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Well-Being After Breast Cancer Surgery
Status: RECRUITING
Conditions: Coping Skills Training for Persistent Post-Surgical Pain|General Health Education
Interventions: BEHAVIORAL: CST-PSP|BEHAVIORAL: General health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Metabolic Effects of Almond Consumption in Adults With Pre-Diabetes
Status: COMPLETED
Conditions: Prediabetes|Insulin Resistance|Metabolic Syndrome
Interventions: BEHAVIORAL: Almonds in a calorie controlled diet|BEHAVIORAL: Nut free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and PK/PD After 4 Weekly SC Injections of PB1046 in Subjects With Stable HFrEF
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: PB1046 Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thrombus Aspiration for OcLuded Coronary Artery Enhanced With Distal Injection Of Abciximab
Status: UNKNOWN
Conditions: Myocardial Infarction|Occlusive Thrombus
Interventions: OTHER: Intracoronary direct injection|OTHER: Intracoronary and distal injection by aspiration device|OTHER: Intracoronary distal injection by aspiration catheter device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)
Status: ACTIVE_NOT_RECRUITING
Conditions: Sedation
Interventions: DRUG: Isoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac CT's Role in Asymptomatic Patients With Diabetes and Metabolic Syndrome
Status: COMPLETED
Conditions: Diabetes|Metabolic Syndrome
Interventions: DIAGNOSTIC_TEST: Cardiac CT|BEHAVIORAL: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Combined Sciatic(Winnie's) Femoral Nerve Block, and Subarachnoid Block Anesthesia for Lower Limb Surgery
Status: COMPLETED
Conditions: Anesthesia Local
Interventions: PROCEDURE: Subarachnoid block|PROCEDURE: combined Femoral and Sciatic nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lanadelumab in FXII-associated Cold Autoinflammatory Syndrome (FACAS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Autoinflammatory Disease
Interventions: DRUG: Lanadelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures
Status: RECRUITING
Conditions: Neonatal Seizure|Neonatal Encephalopathy|Hypoxic-Ischemic Encephalopathy|Seizure Newborn
Interventions: DRUG: Levetiracetam Injection|DRUG: Phenobarbital Sodium Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberculosis, Multidrug-Resistant|Tuberculosis|Pulmonary Tuberculoses|Mycobacterial Infections|Bacterial Infections|Gram-Positive Bacterial Infections
Interventions: DRUG: Bedaquiline 100 MG|DRUG: Delamanid 50 MG Oral Tablet|DRUG: Clofazimine 100 MG Oral Capsule|DRUG: Linezolid 600Mg Tab|DRUG: Control arm MDR-TB regimen, designed according to latest WHO guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telbivudine Versus Entecavir in Reducing Serum HBsAg Levels in Patients With HBeAg-positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Viral Hepatitis B Without Delta-agent
Interventions: DRUG: Telbivudine|DRUG: Entecavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil and Exercise for Post Stroke Fatigue
Status: NOT_YET_RECRUITING
Conditions: Stroke|Fatigue|Modafinil|Exercise
Interventions: DRUG: Modafinil 200mg|DRUG: Placebo|BEHAVIORAL: Exercise Program One|BEHAVIORAL: Exercise Program Two
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sleep Disorders Management, Health and Safety in Police
Status: COMPLETED
Conditions: Sleep Disorders|Sleep Apnea, Obstructive|Restless Legs Syndrome|Sleep Disorders, Circadian Rhythm|Sleep Initiation and Maintenance Disorders
Interventions: BEHAVIORAL: Sleep Hygiene Education|PROCEDURE: Screening and Treatment of Sleep Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Plant-based Polar Lipids on Acute and Second Meal Glucose Tolerance and Appetite Sensations
Status: COMPLETED
Conditions: Healthy Subjects|Diet Intervention
Interventions: OTHER: Non-polar lipids|OTHER: No lipids|DIETARY_SUPPLEMENT: Polar lipids low|DIETARY_SUPPLEMENT: Polar lipids high
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: simvastatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of S-equol on Vasomotor Symptoms in Menopausal Patients
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Placebo|DRUG: S-equol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-arterial Hepatic (IAH) Infusion of Radiolabelled Somatostatin Analogs in GEP-NET Patients With Dominant Liver Metastases
Status: RECRUITING
Conditions: Neuroendocrine Tumor|Liver Metastases|Neuroendocrine Gastroenteropancreatic Tumour
Interventions: PROCEDURE: Positron emission tomography computed tomography (PET/CT) with Intra-hepatic (IAH) injection|PROCEDURE: Positron emission tomography computed tomography (PET/CT) with Intravenous (IV) injection|DRUG: LUTATHERA® by intra-arterial hepatic (IAH) injection|PROCEDURE: Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacking Mesh Versus Self-fixating Mesh for Inguinal Hernia Repair
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: DEVICE: PROLENE Polypropylene Tacking Mesh|DEVICE: ProGrip Self-fixating Mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rural Appalachia Pilot Water Treatment Trial
Status: RECRUITING
Conditions: Water-Related Diseases|Enteric Pathogens|Exposure to Chemical Pollution
Interventions: DEVICE: Countertop pitcher water filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SmartMouth Advanced Clinical Formula Clinical Research Design Protocol
Status: COMPLETED
Conditions: Gingivitis|Periodontitis
Interventions: DRUG: SmartMouth Clinical DDS mouthrinse|DRUG: 0.12% chlorhexidine rinse|DRUG: Placebo rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Apatinib and XELOX Combination Regimen to Treat Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: DRUG: Apatinib and XELOX combined treatment group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic Interaction Between Amlodipine and Losartan
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine10mg|DRUG: Losartan potassium 100mg|DRUG: Amlodipine plus Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency
Status: RECRUITING
Conditions: Pyruvate Dehydrogenase Complex Deficiency
Interventions: DRUG: Triheptanoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laboratory Implications of Non Obstructive Atherosclerotic Plaques Identified by Multiple Detector Coronary Angiotomography
Status: COMPLETED
Conditions: Discrete Coronary Artery Stenosis|Coronary Angiography of Multiple Detectors|Platelet Aggregation, Spontaneous|Cardiovascular Risk Factor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intervertebral DXM Gel Injection in Adults With Painful Lumbar Degenerative Disc Disease
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Chronic Lower Back Pain|Discogenic Pain|Intervertebral Disc Degeneration|Lumbar Disc Disease|Lumbar Disc Degeneration|Lumbar Disc Pain
Interventions: DEVICE: Double Crosslink Microgel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib Combined With Capecitabine Compared With Apatinib Treat Advanced Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Capecitabine|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Digital Peer Mentoring Platform With College Student Populations
Status: COMPLETED
Conditions: Well-Being, Psychological|Anxiety|Depression|Mentoring to Support the Transition to College
Interventions: BEHAVIORAL: MentorPRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Efficacy, Safety and Tolerability Study of Glatiramer Acetate (GA) 20 mg/0.5 ml New Formulation Administered Daily by Subcutaneous (SC) Injection in Subjects With Relapsing-Remitting Multiple Sclerosis (RRMS)
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Glatiramer Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DC/AML Fusion Cell Vaccine vs Observation in Patients Who Achieve a Chemotherapy-induced Remission
Status: RECRUITING
Conditions: Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: DC/AML Fusion Vaccine|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of a Nutritional Supplement on Microbiota, Metabolic Control, Inflammatory Profile, and Quality of Life in Patients With Polycystic Ovary Syndrome.
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Ovapro (Lifepro)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IGHID 12230 - An Implementation Trial of an Experiential Brief Alcohol Intervention for HIV Prevention
Status: RECRUITING
Conditions: HIV-1-infection|Unhealthy Alcohol Use
Interventions: OTHER: Facilitation (FAC)|BEHAVIORAL: Experiential Brief Alcohol Intervention (EBAI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Assess the Bioequivalence of Acalabrutinib Tablet and Acalabrutinib Capsule
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Treatment A: Acalabrutinib tablet|DRUG: Treatment B: Acalabrutinib capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Protein Supplementation on Plasma Sodium Levels and Urinary Urea Excretion in Patients With SIAD
Status: COMPLETED
Conditions: Syndrome of Inappropriate Antidiuresis (SIAD)
Interventions: DIETARY_SUPPLEMENT: Protein supplementation|DIETARY_SUPPLEMENT: Oral urea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sound Estimation and Accuracy Task
Status: COMPLETED
Conditions: Parkinson's|Alzheimer Disease
Interventions: OTHER: Instructions about Overestimates|OTHER: Instructions about Parkinson's|OTHER: Instructions about Underestimates|OTHER: Instructions about Alzheimers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Bonding Quality and Gene Expression in Fullterm Infants Compared to Late Preterm Infants and Preterm Infants With Early Skin to Skin or Visual Contact
Status: UNKNOWN
Conditions: Premature Infant
Interventions: DIAGNOSTIC_TEST: Attachment story completion taks (ASCT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Myofascial Massage for Pain and Immobility Following Breast Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Mastectomy; Lymphedema|Pain, Shoulder|Mobility Limitation
Interventions: OTHER: Myofascial Massage|OTHER: Light Touch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection of Saliva by Immunoaffinity and Mass Spectrometry
Status: NOT_YET_RECRUITING
Conditions: Sexual Assault
Interventions: OTHER: Saliva collection|OTHER: Vaginal secretion collection|OTHER: IP-LC-MS/MS : immunoprecipitation enrichment with liquid chromatography coupled to tandem mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Optimizing the Assessment of Mechanical Ventilation by Integrating Advanced Monitoring Techniques [AVIM]
Status: ENROLLING_BY_INVITATION
Conditions: Mechanical Ventilation Complication|Ventilator-Induced Lung Injury
Interventions: DEVICE: Electric impedance tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metoprolol Succinate in Cardiac Remodeling Related to Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis|Cirrhotic Cardiomyopathy|Cardiac Remodeling
Interventions: DRUG: Metoprolol succinate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study of Gardasil™ (qHPV Vaccine) in Reducing the Incidence of Anogenital Warts in Young Men (V501-020)
Status: COMPLETED
Conditions: Condylomata Acuminata
Interventions: BIOLOGICAL: (Gardasil™) human papillomavirus (types 6, 11, 16, 18) recombinant vaccine|BIOLOGICAL: Comparator: placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Hypertrophic Cardiomyopathy|Cardiac Sarcoidosis|Hypertensive Heart Disease|Tako Tsubo Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy 1|Myocarditis
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI or 18F-AlF-FAPI cardiac PET-MR|DIAGNOSTIC_TEST: Echocardiogram|DIAGNOSTIC_TEST: Cardiac MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HAIC Versus TACE for Large Hepatocellular Carcinoma Staged BCLC A/B.
Status: COMPLETED
Conditions: HepatoCellular Carcinoma
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|PROCEDURE: Transarterial chemoembolization|DRUG: Folfox Protocol|DRUG: TACE Drug Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scientific Substantiation and Assessment of the Effectiveness of Pathogenetic Methods of Therapy for Congenital Ichthyosis in Children
Status: UNKNOWN
Conditions: Congenital Ichthyosis
Interventions: DRUG: Secukinumab Injection|DRUG: Ustekinumab Injection|DRUG: Dupilumab Injection|OTHER: Symptomatic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of Duvelisib in Previously Treated Patients With Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: Duvelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Scoliosis Specific Exercise in Patients With Adolescent Idiopathic Scoliosis During Bracing
Status: ACTIVE_NOT_RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: COMBINATION_PRODUCT: Schroth SSE with Bracing|DEVICE: Bracing alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Subcutaneous Lirentelimab (AK002) in Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: AK002|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof of Concept Study to Determine the Local Delivery and Efficacy of Nanocort
Status: UNKNOWN
Conditions: Atherosclerosis
Interventions: DRUG: Nanocort|DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: