pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: To Compare Anterior Knee Pain Between Non Severe and Severe Patellofemoral Arthritis After Oxford UKA
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DEVICE: Oxford unicompartmental knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FES Cycling and Nutritional Counseling for Battling Obesity After SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: COMBINATION_PRODUCT: HIIT-FES Cycling combined with Nutritional Counseling|OTHER: Nutritional Counseling Only
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Differents Intensities of Passive Stretching on ROM, Neuromuscular and Performance in Soccer Players: A Blinded RCT
Status: UNKNOWN
Conditions: Contracture of Muscle, Thigh|Muscle Rigidity|Strain of Hamstring Muscle (Disorder)
Interventions: OTHER: Passive static stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Post-endodontic Pain After RCT When Intracanal Cryotherapy is Used.
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: Balanced Force technique|PROCEDURE: WaveOne technique|PROCEDURE: Reciproc technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate the Effectiveness of Testosterone Treatment in Men With Multiple Sclerosis
Status: WITHDRAWN
Conditions: Multiple Sclerosis
Interventions: DRUG: testosterone|DRUG: placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of PDE4 Inhibition With Roflumilast for the Management of Plaque Psoriasis
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: DRUG: Roflumilast 0.3% cream|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pentamidine + Salvage Chemo for Relapsed/Refractory Classical Hodgkin Lymphoma
Status: COMPLETED
Conditions: Hodgkin Lymphoma|Refractory Hodgkin Lymphoma
Interventions: DRUG: Pentamidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imipenem/Cilastatin-XNW4107 Versus Imipenem/Cilastatin/Relebactam for Treatment of Participants With Bacterial Pneumonia (XNW4107-302, REITAB-2)
Status: RECRUITING
Conditions: Hospital Acquired Bacterial Pneumonia or Ventilator-Associated Bacterial Pneumonia
Interventions: DRUG: Combination of Imipenem/Cilastatin and XNW4107|DRUG: Imipenem/Cilastatin/Relebactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endotracheal Intubation Using Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope (FIVE) in Obese Patients Undergoing Elective Surgeries Under General Anesthesia: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Flexible Fiberoptic Bronchoscopy Versus Flexible Intubation Video Endoscope FIVE in Obese Patients
Interventions: DEVICE: Flexible fiberoptic bronchoscopy|DEVICE: Fexible intubation video endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Consumption of Oral Artificial Sweeteners on Platelet Aggregation and Polyol Excretion
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: xylitol, 30g|DIETARY_SUPPLEMENT: erythritol, 30g|DIETARY_SUPPLEMENT: xylitol, 5g|DIETARY_SUPPLEMENT: glucose, 30g
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A New Study to Follow-up Thyroid Cancer Patients Who Participated in a Previous Study, Which Compared the Success of Destruction of the Thyroid Remnant Using Standard Treatment or Thyrogen.
Status: COMPLETED
Conditions: Differentiated Thyroid Cancer
Interventions: DRUG: Thyrogen (thyrotropin alfa for injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Delivery of Silk Fibroin and Chlorhexidine
Status: NOT_YET_RECRUITING
Conditions: Periodontal Pocket
Interventions: BIOLOGICAL: silk fibroin|DRUG: Chlorhexidin|BIOLOGICAL: combination of silk fibroin and chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of DWP450 for Treating Crows Feet Lines(CFL) in Combination With Glabellar Lines(Extension Study)
Status: UNKNOWN
Conditions: Crow's Feet Lines|Glabellar Lines
Interventions: DRUG: Clostridium Botulinum A Toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Interval Debulking Surgery by Laparoscopy for Peritoneal Carcinosis in Chemosensitive Patients
Status: COMPLETED
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cavity Cancer
Interventions: PROCEDURE: Tumor Debulking Surgery by laparoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses
Status: COMPLETED
Conditions: Neuromyelitis Optica|Neuromyelitis Optica Spectrum Disorder
Interventions: DRUG: Ublituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial to Treat Diastolic Heart Failure Using Ambrisentan
Status: TERMINATED
Conditions: Pulmonary Hypertension|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Ambrisentan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Safety and Efficacy of Vaniprevir Administered With Pegylated-Interferon and Ribavirin in Japanese Participants With Chronic Hepatitis C Infection (7009-016)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Vaniprevir|DRUG: Pegylated Interferon (peg-IFN)|DRUG: Ribavirin|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer
Status: NOT_YET_RECRUITING
Conditions: Malignant Neoplasm
Interventions: DRUG: Isopropyl Alcohol|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effects of Playing Digital Games on Children's Pain, Fear and Anxiety Levels During Suturing
Status: COMPLETED
Conditions: Pain, Procedural|Fear of Needles|Anxiety State
Interventions: BEHAVIORAL: Digital games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Total Laparoscopic Hysterectomy With Sacrocolpopexy Versus Total Laparoscopic Hysterectomy With Lateral Suspension in Patients With Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: total laparoscopic hysterectomy with sacrocolpopexy|PROCEDURE: total laparoscopic hysterectomy with lateral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dualsite Anodic tDCS on Lower Limbs Function in Patients After Stroke: Randomized, Double-blind, Placebo-controlled, Crossover Trial
Status: UNKNOWN
Conditions: Stroke, Chronic
Interventions: DEVICE: Transcranial direct current stimulation (Anodal tDCS) + dual-task training|DEVICE: Transcranial direct current stimulation (tDCS dualsite) + dual-task traning|DEVICE: Transcranial direct current stimulation sham + dual-task training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Early Use of Levosimendan Versus Placebo on Top of a Conventional Strategy of Inotrope Use on a Combined Morbidity-mortality Endpoint in Patients With Cardiogenic Shock
Status: RECRUITING
Conditions: Cardiogenic Shock
Interventions: DRUG: Levosimendan 2.5 MG/ML Injectable Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RAPIDIRON Trial Follow-up Study: RAPIDIRON-KIDS Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Iron Deficiency Anemia|Neurodevelopmental Abnormality|Autism Spectrum Disorder
Interventions: DRUG: Ferric carboxymaltose|DRUG: Iron isomaltoside|DRUG: Ferric Sulfate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Clinical Evaluation to Compare Vanguard Cruciate Retaining and AGC Total Condylar Knee Implants
Status: COMPLETED
Conditions: Osteoarthritis|Rheumatoid Arthritis|Traumatic Arthritis
Interventions: DEVICE: Vanguard CR|DEVICE: AGC knee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects on Growth and Tolerance of a Routine Infant Formula Fed to Term Infants
Status: COMPLETED
Conditions: Growth of Term Infants
Interventions: OTHER: Control: Marketed routine infant formula|OTHER: An investigational infant formula containing an alternate source of DHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Antioxidant and Immune Effects of Vitamin K2
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation
Interventions: DIETARY_SUPPLEMENT: Vitamin K2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diabetic Neuropathy Topical Treatment
Status: UNKNOWN
Conditions: Diabetic Neuropathy|Pain
Interventions: DRUG: ketamine|DRUG: vehicle gel|DRUG: ketamine + clonidine|DRUG: clonidine gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic HIIT-RT Study
Status: COMPLETED
Conditions: Metabolic Diseases|Overweight|Motor Activity
Interventions: BEHAVIORAL: High Intensity Interval|BEHAVIORAL: Resistance training|BEHAVIORAL: Plus: High Intensity Interval + Resistance Training|OTHER: Usual clinical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Nebulized Heparin for the Treatment of COVID-19
Status: COMPLETED
Conditions: Covid19|Pneumonia, Viral
Interventions: DRUG: Heparin|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Impact of Treating and Safely Storing Shallow Tubewell Drinking Water
Status: COMPLETED
Conditions: Diarrhoeal Disease
Interventions: DRUG: Sodium dichloroisocyanurate (NaDCC) tablet (Aquatab)|DEVICE: Water storage container (Jerry can)|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Essential Oils Mouth Rinse and Dental Floss: Efficacy on Interproximal Gingivitis and Dental Plaque Accumulation
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque Accumulation
Interventions: DRUG: Essential oils mouthrinse|DEVICE: Dental Floss
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multihance at 3 Tesla (3T) in Brain Tumors
Status: COMPLETED
Conditions: Brain Tumor
Interventions: DRUG: Multihance|DRUG: Arm 2 - Magnevist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A f-MRI Study Of Affective Changes Associated With Four Weeks Consumption Of A Fermented Dairy Product In Healthy Women
Status: COMPLETED
Conditions: Healthy Adult Women
Interventions: OTHER: 1-Fermented Dairy Product (test)|OTHER: 2-Milk-based non-fermented dairy product(control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Melatonin for Cerebral Palsy Children's Sleep and Health
Status: COMPLETED
Conditions: Cerebral Palsy|Melatonin|Growth|Children, Only
Interventions: DRUG: Melatonin 3 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Agility Training and Its Relations in Elderly Adults With and Without MCI
Status: NOT_YET_RECRUITING
Conditions: Elderly Adults|Mild Cognitive Impairment|Healthy
Interventions: OTHER: Health education|OTHER: Multicomponent training|OTHER: Agility training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX)
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: ZYN002 - Cannabidiol Transdermal Gel|OTHER: Placebo Transdermal Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Severe Covid-19 in Infected Elderly by Early Administration of Convalescent Plasma With High-titers of Antibody Against SARS-CoV2
Status: COMPLETED
Conditions: COVID
Interventions: BIOLOGICAL: Convalescent Plasma|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease|General Anesthetic Drug Allergy|Coronary Artery Bypass Graft Surgery
Interventions: DRUG: Xenon|DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Prevention Of Respiratory Tract Infection And Covid-19 Through BCG Vaccination In Vulnerable Older Adults
Status: COMPLETED
Conditions: Respiratory Tract Infections|Covid19
Interventions: DRUG: Bacille Calmette-Guérin (BCG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Long-Term Extension Study of WA22762 and NA25220 of Subcutaneous (SC) Tocilizumab (TCZ) in Moderate to Severe Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of the Effect of Bardoxolone Methyl on the Single Dose Pharmacokinetics of Digoxin and Rosuvastatin in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Digoxin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate Safety, Efficacy and Pharmacokinetics
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: CT-P6|DRUG: Herceptin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cerebral Activation by fNIRS During Vibration-induced Illusion of Movement in Healthy and Stroke Participants.
Status: RECRUITING
Conditions: Healthy|Stroke, Acute
Interventions: OTHER: vibration-induced illusion of movement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RCT About Two Different Regimens of Clean Intermittent Catheterization in Women With Overt Postpartum Urinary Retention
Status: RECRUITING
Conditions: Urinary Retention|Postpartum Period
Interventions: PROCEDURE: Intermittent catheterization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Irinotecan|DRUG: Cisplatin|DRUG: Olaparib (for levels 1 and 5)|DRUG: Olaparib (for dose level 2)|DRUG: Mitomycin-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Status: RECRUITING
Conditions: Psychosis Associated With Alzheimer's Disease
Interventions: DRUG: KarXT|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Infection|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms|Precancerous Condition|Secondary Myelofibrosis|Small Intestine Cancer
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: melphalan|DRUG: methotrexate|DRUG: sirolimus|DRUG: tacrolimus|PROCEDURE: allogeneic hematopoietic stem cell transplantation|PROCEDURE: hematopoietic stem cell transplantation|PROCEDURE: nonmyeloablative allogeneic hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: total-body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: This Research Hypothesizes That the Use of a Rigid Rocker Sole Reduces the Recurrence Rate of Diabetic Foot Ulcers in Patients With Peripheral Neuropathy.
Status: COMPLETED
Conditions: Diabetic Foot|Diabetic Foot Ulcer
Interventions: DEVICE: Rigid Rocker Sole Footwear|DEVICE: Therapeutic Footwear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Pregnancy and Pregnancy Outcomes in Women With Breast Cancer Treated With Trastuzumab, Pertuzumab in Combination With Trastuzumab, or Ado-Trastuzumab Emtansine
Status: COMPLETED
Conditions: Breast Cancer|Pregnancy
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Ado-Trastuzumab Emtansine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hemodynamic Responses of Different Laryngoscopes
Status: COMPLETED
Conditions: Heart Rate and Rhythm Disorders|Blood Pressures|Oxygen Disorders
Interventions: DEVICE: Macintosh laryngoscope|DEVICE: Mc-Coy laryngoscope|DEVICE: C-Mac videolaryngoscope|DEVICE: McGrath videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maximizing Nutrition Education to Meet Dietary and Food Security of Children and Parents
Status: RECRUITING
Conditions: Nutrition, Healthy|Hunger|Diet, Healthy|Food Habits
Interventions: BEHAVIORAL: the Supplemental Nutrition Assistance Program-Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bumetanide in Patients With Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Bumetanide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Two Different Preparations of Sevoflurane in Induction
Status: COMPLETED
Conditions: Coughing on Induction|Vapors; Inhalation
Interventions: DRUG: Sevoflurane|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Use of Intraperitoneal Ropivacaine in Bariatric Bypass Surgery
Status: COMPLETED
Conditions: Bariatric Surgery Candidate
Interventions: DRUG: Ropivacaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Of PF-05190457 In Healthy Volunteers And Type-2 Diabetic Patients
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo|DRUG: PF-05190457 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of Repeat Topical Application of BOS-356 in Subjects With Moderate to Severe Acne Vulgaris
Status: COMPLETED
Conditions: Moderate to Severe Acne Vulgaris
Interventions: DRUG: BOS-356|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Qizhitongluo Capsule in the Recovery Phase of Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Qizhitongluo Capsule|DRUG: Naoxintong Capsule|DRUG: Aspirin Enteric-coated Tablets|BEHAVIORAL: the routine recovery training|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Predictive Value of Clinical Data on Perioperative and Postoperative Risk Events in Patients With Head and Neck Artery Stenosis
Status: RECRUITING
Conditions: Postoperative Risk Factors for Patients With Carotid Artery Stenosis
Interventions: PROCEDURE: Head and neck vascular recanalization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study
Status: COMPLETED
Conditions: Neoplasms|Fatigue
Interventions: OTHER: Bright White Light|OTHER: Dim Red Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Modified Endotracheal Intubation Protocol Combined With Early Oral Intake on Postoperative Recovery Quality in Thyroid and Parathyroid Surgery
Status: COMPLETED
Conditions: Thyroid Tumor
Interventions: BEHAVIORAL: Modified intubation protocol|BEHAVIORAL: Conventional intubation protocol|BEHAVIORAL: Early resumption of oral intake|BEHAVIORAL: Delayed resumption of oral intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CONtinuous Implantable DOppler Probe Monitoring in Renal Transplantation
Status: COMPLETED
Conditions: Renal Artery Complications|Renal Vein Thrombosis
Interventions: DEVICE: Implantable Doppler probe manufactured by COOK Medical Company.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease|Central Nervous System Diseases
Interventions: DRUG: EVP-6124 (0.1 mg/day)|DRUG: EVP-6124 (0.3 mg/day)|DRUG: EVP-6124 (1.0 mg/day)|DRUG: Comparator: Placebo|DRUG: Donepezil|DRUG: Rivastigmine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of the VeraCept Low-Dose Intrauterine Copper Contraceptive vs. the TCu380 Copper IUD
Status: COMPLETED
Conditions: Prevention of Pregnancy
Interventions: DEVICE: VeraCept Intrauterine Copper Contraceptive|DEVICE: TCu380 IUD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Research Study Designed To Determine If Treatment of Hepatitis C With Milk Thistle is More Effective Than No Treatment In Patients Infected With Both HIV And Hepatitis C
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: Silymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nesiritide - Dilated Cardiomyopathy
Status: COMPLETED
Conditions: Dilated Cardiomyopathy
Interventions: DRUG: Nesiritide|DRUG: 5% Dextrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis|Constipation|Gastrointestinal Motility Disorder|Autonomic Dysfunction
Interventions: DEVICE: Transcutaneous Electrical Acustimulation (TEA)|DEVICE: Sham-TEA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Developing and Testing Waterpipe-specific Health Warning Labels
Status: RECRUITING
Conditions: Waterpipe Smoking|Health Warning Label|Harm Perception|Puffing Behaviour|Quitting Smoking|Health Risk Behaviors
Interventions: BEHAVIORAL: Test Health Warning Label (HWL)|BEHAVIORAL: Test without Health Warning Label (no-HWL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Safety App to Respond to Dating Violence for College Women and Their Friends
Status: COMPLETED
Conditions: Intimate Partner Violence
Interventions: BEHAVIORAL: Usual Care Safety Planing App|BEHAVIORAL: Personalized App-Based Safety Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Prospective Study of Benznidazole for Chagas' Disease Children With Chronic Indeterminate Chagas Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chagas Disease
Interventions: DRUG: Benznidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
Status: RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mangafodipir as an Adjunct to Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Mangafodipir|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Monitoring Study
Status: COMPLETED
Conditions: Type1diabetes
Interventions: DEVICE: Bihormonal Bionic Pancreas|DEVICE: Insulin Only Bionic Pancreas|OTHER: Monitored for Hypoglycemia|OTHER: Not Monitored for Hypoglycemia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD
Status: NOT_YET_RECRUITING
Conditions: Non-Alcoholic Fatty Liver Disease|Type2diabetes
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Pioglitazone 15mg|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cold Packs, Lidocaine and Flash Lights on Cannulation Pain in Hemodialysis Patients
Status: NOT_YET_RECRUITING
Conditions: Arteriovenous Graft Site Pain
Interventions: DRUG: Lidocaine topical|OTHER: cold packs|DEVICE: flash lights
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of Iloprost Inhaled Solution as Add-On Therapy With Bosentan in Subjects With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension|Ayerza Syndrome|Pulmonary Hypertension
Interventions: DRUG: Iloprost or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults
Status: COMPLETED
Conditions: Pneumonia, Pneumococcal|Pneumococcal Infections|13-valent Pneumococcal Vaccine
Interventions: BIOLOGICAL: VACCINE: placebo|BIOLOGICAL: VACCINE: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of a Dietary Supplement on Weight Loss and Psychological Wellbeing in Overweight Individuals
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Consumption of dietary supplement.|OTHER: Consumption of control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Plurogel® Compared to Standard Topical Dressing in Burn Injuries
Status: RECRUITING
Conditions: Burns
Interventions: DRUG: Standard dressing|DRUG: PluroGel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy on Glycemic Variability and Safety of Gemigliptin Compared With Dapagliflozin Added on Metformin Alone or Diabetes Medication Naïve Patient in Type 2 Diabetes Mellitus (Stable II Study)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Gemigliptin 50mg|DRUG: Dapagliflozin 10mg|PROCEDURE: Diet/exercise questionnaire|DEVICE: Continuous Glucose Monitoring System(CGMS)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects
Status: WITHDRAWN
Conditions: Pharmacokinetics|Healthy Male Subjects|Safety|Food Effect
Interventions: DRUG: AZD9977 immediate release (IR) oral suspension|DRUG: AZD9977 extended release (ER) capsules [fast]|DRUG: AZD9977 extended release (ER) capsules [intermediate]|DRUG: AZD9977 extended release (ER) capsules [slow]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Web-based Mindfulness Meditation in Reducing Distress in Participants With Metastatic Gastrointestinal Cancer and Their Caregivers
Status: COMPLETED
Conditions: Caregiver|Metastatic Gastrointestinal Carcinoma
Interventions: BEHAVIORAL: Online Mindfulness Meditation|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Personalized Spine Study Group (PSSG) Registry
Status: RECRUITING
Conditions: Scoliosis; Adolescence|Degenerative Disc Disease|Spinal Fusion|Kyphoscoliosis|Pseudoarthrosis of Spine|Spinal Stenosis|Kyphoses, Scheuermann
Interventions: DEVICE: Patient Specific Rod
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Deformation Imaging by Strain in Chronic Heart Failure Over Gliflozins: an Echocardiographic Register on Sodium-GLucose coTransporter-2 Inhibitors
Status: UNKNOWN
Conditions: Sodium-GLucose coTransporter-2 Inhibitors|Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Sodium-GLucose coTransporter-2 inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carotid Atorvastatin Study in Hyperlipidemic Post-Menopausal Women
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: PROCEDURE: Echographic measurements|PROCEDURE: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of QL1206 in the Treatment of Postmenopausal Osteoporosis With High Fracture Risk
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: QL1206|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of a Vaccine for Severe Acute Respiratory Syndrome (SARS)
Status: COMPLETED
Conditions: Healthy
Interventions: PROCEDURE: Blood Test|PROCEDURE: Urine Test|PROCEDURE: Physical Exam|DRUG: Vaccine|DRUG: VRC-SRSDNA015-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty
Status: COMPLETED
Conditions: Osteoarthritis, Hip|Femur Head Necrosis|Femoral Neck Fractures
Interventions: DRUG: Rivaroxaban|DRUG: Enoxaparin|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intervention Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Non-suicidal Self-injury (NSSI)
Status: RECRUITING
Conditions: Transcranial Direct Current Stimulation|Non Suicidal Self Injury
Interventions: DEVICE: High-Definition transcranial Direct Current Stimulation (HD-tDCS)|DEVICE: sham High-Definition transcranial Direct Current Stimulation (HD-tDCS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Studying DNA in Tissue Samples From Caucasian and African-American Cancer Patients Who Received Docetaxel on Clinical Trial CLB-9871
Status: COMPLETED
Conditions: Bladder Cancer|Breast Cancer|Head and Neck Cancer|Lung Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Are Sugar-Sweetened Beverage Information Labels Well-Targeted
Status: COMPLETED
Conditions: Soft Drink Consumption|Sugar-sweetened Beverages|Information Labels
Interventions: OTHER: Nutrition Facts|OTHER: Text Warning|OTHER: Graphic Warning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Early Safety and Efficacy Study of Ascites Management: Standard Paracentesis or Early Intervention With Pleurx Catheters in Patients With Malignant Ascites
Status: TERMINATED
Conditions: Malignant Ascites
Interventions: PROCEDURE: paracentesis|DEVICE: Pleurx catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Bevacizumab for Idiopathic Macular Telangiectasia
Status: COMPLETED
Conditions: Retina|Telangiectasis
Interventions: DRUG: Intravitreal Injection of Bevacizumab (1.25 mg/0.05ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tilt Cardiopulmonary Resuscitation With a Feedback Device
Status: COMPLETED
Conditions: Cardiopulmonary Resuscitation|Basic Cardiac Life Support
Interventions: DEVICE: Audiovisual feedback from smartphone based app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sex Differences in Coronary Pathophysiology
Status: RECRUITING
Conditions: Chest Pain|Ischemia
Interventions: PROCEDURE: 30 cc blood draw|PROCEDURE: Intravascular ultrasound (IVUS)|PROCEDURE: Coronary pressure/flow wire testing|PROCEDURE: Coronary pressure/flow testing: Acetycholine challenge|PROCEDURE: Procedure: Coronary pressure/flow testing: Nitroglycerin challenge|PROCEDURE: Procedure: Procedure: Coronary pressure/flow testing: Adenosine challenge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial of Immunological Outcomes of Sublingual Immunotherapy for House Dust Mite (D. Pteronyssinus) Allergy
Status: COMPLETED
Conditions: Allergic Rhinitis|Asthma
Interventions: DRUG: (agent for immunotherapy) Staloral|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RT-CGM in Young Adults at Risk of DKA
Status: UNKNOWN
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Metabolic Disease|Autoimmune Diseases|Endocrine System Diseases
Interventions: DEVICE: Dexcom G6|DEVICE: Self monitoring of blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors
Status: UNKNOWN
Conditions: Solid Tumor|Hepatocellular Carcinoma|Colorectal Cancer|Glioma
Interventions: DRUG: KD-025 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: Rilonacept|OTHER: Placebo (for Rilonacept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Frontal Sinusitis by a Simple Technique Using Dilation Balloons
Status: TERMINATED
Conditions: Frontal Sinusitis
Interventions: PROCEDURE: Functional Endoscopic Sinus Surgery|PROCEDURE: Functional Endoscopic Sinus Surgery using rigide instrumentation|DEVICE: Sinuplasty balloon|DEVICE: Endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intradialytic Physiotherapy in Patients With Chronic Kidney Disease
Status: RECRUITING
Conditions: Chronic Renal Diseases
Interventions: DEVICE: Neuromuscular electrical stimulation (NMES) - Active|DEVICE: Neuromuscular Electrical Stimulation (NMES) - Sham|DEVICE: Aerobic exercise with cycle ergometer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Felodipine Event Reduction Study
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Felodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia
Status: TERMINATED
Conditions: Presbyopia
Interventions: DRUG: AGN-241622|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world Study
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: TKIs
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of pegInterferon Alfa-2a, Ribavirin, and Daclatasvir (BMS-790052) With or Without BMS-650032 for Participants in Some Hepatitis C Virus Trials
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: Daclatasvir|DRUG: Asunaprevir|DRUG: Pegylated interferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perioperative Iron With Erythropoietin in Bilateral Total Knee Replacement Arthroplasty (TKRA)
Status: COMPLETED
Conditions: Anemia|Transfusion
Interventions: DRUG: iron sucrose, erythropoietin-β|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-response Effect of Alcohol Ingestion on Steroid Profile
Status: COMPLETED
Conditions: Alcohol Consumption|Healthy
Interventions: DIETARY_SUPPLEMENT: 10 g ethanol|DIETARY_SUPPLEMENT: 20 g ethanol|DIETARY_SUPPLEMENT: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reduction of Myocardial Infarction by Preconditioning in Patients With Ruptured Abdominal Aortic Aneurysm
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: PROCEDURE: Precondition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DCs Vaccine Combined With Cytokine-induced Killer Cells in Patients With AML
Status: RECRUITING
Conditions: High-risk Soft Tissue Sarcoma
Interventions: BIOLOGICAL: Adenovirus-transfected DC + CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-response of Anteroposterior Mobilizations in Weight Bearing Talus Dorsiflexion
Status: COMPLETED
Conditions: Aging Problems
Interventions: PROCEDURE: Posteriorization of the talus.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The PAI Trial for Breast and Colon Cancer Survivors
Status: WITHDRAWN
Conditions: Breast Cancer|Colon Cancer
Interventions: COMBINATION_PRODUCT: PAI Tool and Exercise Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of safEty, Tolerability, Radiation Dosimetry, and Imaging Properties of 89Zr-labeled giRenTuximab (89Zr-Girentuximab) in patIents With Non-musclE-iNvasive Bladder CancEr (NMIBC)
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: DRUG: 89Zr-TLX250 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating ABT-414 in Japanese Subjects With Malignant Glioma
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma Multiforme
Interventions: RADIATION: Whole Brain Radiation|DRUG: Temozolomide|DRUG: ABT-414
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT