pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Biceps Tenodesis Versus Tenotomy
Status: COMPLETED
Conditions: Rotator Cuff Tear|Long Head of Biceps Brachii Lesions
Interventions: PROCEDURE: Biceps Tenotomy|PROCEDURE: Biceps Tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Safety and Pharmacokinetics of Standard Antibiotic Therapy, Plus Aurexis® or Placebo, for Treatment of Staphylococcus Aureus Bacteremia (SAB)
Status: COMPLETED
Conditions: Staphylococcus Aureus Bacteremia
Interventions: DRUG: Aurexis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Clinical Study to Investigate Safety and Tolerability and Pharmacokinetics of Multiple Ascending Doses of CM3.1-AC100 in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: CM3.1-AC100|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Compassionate Use of Erwinase For Pediatric Patients With Acute Lymphoblastic Leukemia Or Non Hodgkins Lymphoma
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Non Hodgkins Lymphoma
Interventions: DRUG: Erwinase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of the Abutment-Prosthesis Connection on Marginal Bone Loss and Gingival Sealing Around Dental Implants
Status: RECRUITING
Conditions: Jaw, Edentulous, Partially
Interventions: DEVICE: Connect®|DEVICE: Multi-unit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Optimization of a Digital Self-guided Psychological Intervention for Insomnia: A Randomized Factorial Experiment
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia
Interventions: BEHAVIORAL: Digital self-guided psychological intervention for insomnia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Ibuprofen 400 mg/10 mL Oral Suspension vs. MOMENTACT 400 mg Film-coated Tablet
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibuprofen 400 mg/10 mL oral suspension|DRUG: MOMENT 400 mg coated tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety, Efficacy, and Pharmacodynamics of a 60-Minute Infusion of Carfilzomib for Progressive Multiple Myeloma
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Chemo-Induced Peripheral Neuropathy in Multiple Myeloma Patients
Status: TERMINATED
Conditions: Chemotherapy-induced Peripheral Neuropathy
Interventions: OTHER: Acupuncture|OTHER: Standard of Care CIPN management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospectively Defining Metastatic Pancreatic Ductal Adenocarcinoma Subtypes by Comprehensive Genomic Analysis
Status: RECRUITING
Conditions: Cancer|Pancreatic Cancer
Interventions: PROCEDURE: Tumour Biopsy|OTHER: Serial Collection of Plasma and Serum Samples
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Subcutaneous Mircera in Patients With Chronic Kidney Disease, Not on Dialysis.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Mircera|DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Serum Skin Test and Serum IL-18 Levels in Chronic Idiopathic Urticaria and Respiratory Allergic Diseases
Status: COMPLETED
Conditions: Urticaria|Respiratory Allergic Diseases
Interventions: PROCEDURE: autologous serum skin test, serum IL-18
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Chronic Kidney Disease
Interventions: DRUG: Finerenone (BAY94-8862 ) 10 mg|DRUG: Empagliflozin|DRUG: Empagliflozin Placebo|DRUG: Finerenone (BAY94-8862 ) 20 mg|DRUG: Finerenone Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: GSK3640254|DRUG: Darunavir/Ritonavir (DRV/RTV)|DRUG: Etravirine (ETR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prediction of Cardiovascular Events in Vulnerable Patients Following Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: OTHER: EndoPAT testing (non invasive device)|OTHER: WatchPAT testing (non-invasive device)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cancer and Osteoporosis Research With Alendronate and Lupron (C.O.R.A.L )
Status: TERMINATED
Conditions: Osteoporosis
Interventions: DRUG: Alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Puff Biofeedback to Reduce Smoking Reinforcement
Status: COMPLETED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Puff Topography Biofeedback Training|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recombinant Human Thrombopoietin for Mobilization of Peripheral Blood Progenitor Cells for Autologous Transplantation
Status: UNKNOWN
Conditions: Thrombocytopoietin|Hematopoietic Stem Cell Mobilization|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Recombinant Human Thrombopoietin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mobile Coping Skills Training to Improve Cardiorespiratory Failure Survivors' Psychological Distress
Status: COMPLETED
Conditions: Cardiorespiratory Failure
Interventions: BEHAVIORAL: Coping skills training mobile app with call from CST therapist|BEHAVIORAL: Coping skills training mobile app only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Radiation Therapy in Combination With Xeloda, for Initially Metastatic, Low and Middle Rectal Cancer
Status: TERMINATED
Conditions: Rectal Cancer|Metastasis|Radiotherapy
Interventions: COMBINATION_PRODUCT: IMRT + oral chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MITHRIDATE: Ruxolitinib Versus Hydroxycarbamide or Interferon as First Line Therapy in High Risk Polycythemia Vera
Status: RECRUITING
Conditions: Polycythemia Vera
Interventions: DRUG: Ruxolitinib|DRUG: Hydroxycarbamide|DRUG: Interferon-Alpha
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delineation of Reducing Clinical Target Volume for Early-stage Nasopharyngeal Carcinoma Patients
Status: COMPLETED
Conditions: Target Volume Delineation|Early-stage Nasopharyngeal Carcinoma|Intensity Modulated Radiation Therapy
Interventions: RADIATION: Reducing CTV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of High-velocity Resistance Training and Creatine Supplementation in Healthy Aging Males
Status: UNKNOWN
Conditions: Sarcopenia
Interventions: DRUG: Creatine monohydrate|DRUG: Maltodextrin Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
Status: UNKNOWN
Conditions: Myelogenous Leukemia, Chronic
Interventions: DRUG: flumatinib|DRUG: imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison High-density Silicone Oils in Retinal Detachment
Status: WITHDRAWN
Conditions: Retinal Detachment
Interventions: DRUG: Oxane HD [oil-RMN3-mixture]|DRUG: Densiron [(F6H8)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Acalabrutinib in CNSL
Status: RECRUITING
Conditions: Central Nervous System Lymphoma|Refractory Central Nervous System Lymphoma|Recurrent Central Nervous System Lymphoma
Interventions: DRUG: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Natalizumab to Treat Multiple Sclerosis (MS)
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis|Secondary Progressive Multiple Sclerosis
Interventions: DRUG: natalizumab|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS)
Status: TERMINATED
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Atacicept|DRUG: Atacicept|DRUG: Atacicept|DRUG: Placebo matched to atacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Dexmedetomidine and Propofol on the Cardiovascular Autonomic Nervous System During Spinal Anesthesia
Status: COMPLETED
Conditions: Spinal Anesthesia|Autonomic Nervous System
Interventions: DRUG: Propofol|DRUG: Dexmedetomidin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electrical Stimulation of the Quadriceps and Diaphragm in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness Myopathy|Respiration, Artificial
Interventions: PROCEDURE: Electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Lidocaine Infusion for Management of Perioperative Burn Pain
Status: COMPLETED
Conditions: Thermal Burns
Interventions: DRUG: Lidocaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Perception Following Computer-Controlled vs. Conventional Dental Anesthesia
Status: COMPLETED
Conditions: Pain Perception
Interventions: DEVICE: Computer-controlled Local Anaesthesia (CCLA)|DEVICE: Conventional Local Anaesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Culturally Tailored Scalable Asthma Intervention for Hispanic Children (Asthma Guardian)
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Access to Asma Guardian website/app|BEHAVIORAL: Delayed Access to Asma Guardian website/app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Understanding the Determinants of Mucosal Immunity and Optimizing the Diagnosis of Infection With SARS-CoV-2 Variants
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Blood sample collection|OTHER: Saliva sample collection|OTHER: Nasopharyngeal and nasal sample collection|OTHER: Exhaled Breath Condensate (EBC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of PARP in Combination With Dacarbazine
Status: COMPLETED
Conditions: Melanoma Neoplasms
Interventions: DRUG: KU-0059436 (AZD2281)(PARP inhibitor)|DRUG: dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study
Status: WITHDRAWN
Conditions: Acute Decompensated Heart Failure
Interventions: DRUG: Cardiac Perfusion and Metabolism with [11C] Acetate PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
Status: RECRUITING
Conditions: Anal Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|HIV Infection|Kaposi Sarcoma|Lymphoma|Malignant Solid Neoplasm|Multicentric Castleman Disease|Plasmablastic Lymphoma|Recurrent Kaposi Sarcoma|Recurrent Lymphoma|Recurrent Plasmablastic Lymphoma|Transplant-Related Kaposi Sarcoma
Interventions: PROCEDURE: Biospecimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Different Regimens of Transarterial Chemoembolization for Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: Transarterial chemoembolization (TACE)|PROCEDURE: Transarterial chemoembolization (TACE)|PROCEDURE: Transarterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immune Response on Neoadjuvant Therapy in Non-small-cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-small-cell Lung
Interventions: DRUG: Docetaxel|DRUG: oxaliplatin|DRUG: cetuximab|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin in Diuretic Refractory Ascites
Status: COMPLETED
Conditions: Liver Cirrhosis|Cirrhosis|Ascites|Ascites Hepatic|Sodium-Glucose Transporter 2 Inhibitors
Interventions: DRUG: Empagliflozin 10 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroporation Potentiated Immunotherapy in Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreas Cancer, Metastatic
Interventions: DRUG: Pembrolizumab|DEVICE: Irreversible electroporation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies to Improve Pain and Enjoy Life
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Pain self-management training|BEHAVIORAL: video education, motivational interviewing|BEHAVIORAL: voluntary self-paced opioid taper|BEHAVIORAL: prescribing guidance for primary care provider|OTHER: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Versus Transobturator Paravaginal Repair
Status: COMPLETED
Conditions: Cystocele
Interventions: PROCEDURE: Transobturator Paravaginal Repair|PROCEDURE: traditional transvaginal Paravaginal Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement
Status: COMPLETED
Conditions: Smoking|Smoking, Tobacco|Smoking, Cigarette|Lung Cancer
Interventions: BEHAVIORAL: Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale)|BEHAVIORAL: Patient Trust in the Medical|BEHAVIORAL: Decision Conflict Scale (DCS) - Lung Cancer Screening|BEHAVIORAL: Shared Decision Making Questionnaire (SDM-Q)- Patient|BEHAVIORAL: Stage of Readiness for Smoking Cessation - Contemplation Ladder|BEHAVIORAL: Primary Care Clinicians' Lung Cancer Screening Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Pancreatic Adenocarcinoma|Metastatic Pancreatic Adenocarcinoma|Stage IV Pancreatic Cancer AJCC v8
Interventions: DRUG: Gemcitabine|DRUG: Hydroxychloroquine|DRUG: Nab-paclitaxel|DRUG: Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First Step Towards Ultra-hypofractionation for Unfavourable Intermediate and High-risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Adaptive radiotherapy according to UPRATE protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Status: RECRUITING
Conditions: Atrial Fibrillation|Atrial Arrhythmia|Atrial Flutter|Atrial Tachycardia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD
Status: COMPLETED
Conditions: Traumatic Brain Injury|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitively Augmented Behavioral Activation|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plateau Antibody Levels of a Recombinant (E.Coli) HPV Nonavalent Vaccine Versus Gardasil®9 in Young Women
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Condylomata Acuminata
Interventions: BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli)|BIOLOGICAL: Gardasil®9
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of a CBT Online-based Program to Reduce Suicide Ideation Among School Adolescents
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: BEHAVIORAL: Reframet IT|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemetrexed Combined With Synchronous Gefitinib as Adjuvent Therapy in Patient With EGFR Mutant Lung Adenocarcinoma
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: DRUG: Gefitinib|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Carbon Dioxide Gas Versus Heated Humidified Gas in Gynaecological Laparoscopy
Status: UNKNOWN
Conditions: Heated Humidified Carbon Dioxide in Gynaecological Laparoscopic Surgery
Interventions: DEVICE: Standard cold carbon dioxide gas|DEVICE: Heated humidified carbon dioxide gas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of Japanese Encephalitis Vaccine Co-administered With Measles-Mumps-Rubella Vaccine (MMR)
Status: RECRUITING
Conditions: Japanese Encephalitis|Measles|Mumps|Rubella
Interventions: BIOLOGICAL: Vero cell-drived inactive Japanese encephalitis vaccine|BIOLOGICAL: Measles-Mumps-Rubella Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cetuximab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Unresectable Stage IIIA or Stage IIIB Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: carboplatin|DRUG: paclitaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Dietary Supplements in Chronic Smokers Having Mild to Moderate Hyperlipidemia
Status: UNKNOWN
Conditions: Chronic Smokers|Hyperlipidemia
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: BioTurmin (Curcuma longa rhizomes extract)|DIETARY_SUPPLEMENT: BioTurmin-WD (Water dispersible curcuminoids)|DIETARY_SUPPLEMENT: MaQxan (Tagetes erecta flower extract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Predictive Factors of Morbidity and Mortality and Overall Survival of Patients With Gastric Cancer : a Case Series
Status: COMPLETED
Conditions: Gastric Cancer|Mortality of Gastric Cancer|Overall Survival of Patients With Gastric Cancer
Interventions: PROCEDURE: Total or subtotal gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BTL Emsella Chair Versus Sham for the Treatment of Fecal Incontinence
Status: WITHDRAWN
Conditions: Fecal Incontinence
Interventions: DEVICE: BTL Emsella|DEVICE: Sham BTL Emsella
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Impact of L-PRF, H-PRF or the Use of Surgical Stent on Palatal Donor Site Healing.
Status: COMPLETED
Conditions: Lack of Keratinized Gingiva
Interventions: BIOLOGICAL: L-PRF (Leucocyte- platelet rich fibrin)|BIOLOGICAL: H-PRF (Horizontal -platelet rich fibrin)|DEVICE: Surgical stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Application of 18F-FDOPA PET and Magnetic Resonance Spectroscopy (MRS) With HCV and PD
Status: UNKNOWN
Conditions: Hepatitis C|Hepatitis B|Parkinson Disease
Interventions: DRUG: 18F-DOPA PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Study on the Treatment of Mixed Component Cornea for High Risk Keratoplasty
Status: UNKNOWN
Conditions: Corneal Transplantation
Interventions: PROCEDURE: Limbal transplantation combined with central penetrating keratoplasty|PROCEDURE: Limbal transplantation combined with central penetrating keratoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritive Efficacy and Safety of a Modified Infant Formula With a Reduced Protein Content and Improved Protein Quality
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Standard infant formula|DIETARY_SUPPLEMENT: Protein reduced alpha-lactalbumin formula, with higher levels of alpha-lactalbumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Botulinum Toxin Type A (Botox) in the Management of Levodopa-Induced Peak-Dose Dyskinesias in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson Disease
Interventions: BIOLOGICAL: Botulinum Toxin Type A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premedication by Midazolam for Emergency Surgery
Status: COMPLETED
Conditions: Anxiety
Interventions: DRUG: placebo administration|DRUG: midazolam intravenous administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin to Improve Results in Cleft Lip Repair
Status: UNKNOWN
Conditions: Scar
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Botulinum Type A|DRUG: Normal Saline|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sufentanil Used by Paramedics to Treat Pain in Acute Trauma
Status: COMPLETED
Conditions: Trauma Injury|Pain
Interventions: OTHER: Sufentanil administered by paramedics after the phone call consultation of medical doctor.|OTHER: Sufentanil administered by paramedics based on their competency, without consultation of medical doctor.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CT Window Setting to Select Double-lumen Tube Size
Status: COMPLETED
Conditions: Bronchial Cuff Volume at Air-tight Seal|Intracuff Cuff Pressure at Air-tighe Seal
Interventions: DEVICE: Width 1000 HU/Level -450 HU|DEVICE: Width 400 HU/Level 25 HU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Lateral Mesh Suspension for Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Pelvic Floor Prolapse
Interventions: PROCEDURE: Laparoscopic lateral suspension with mesh|DIAGNOSTIC_TEST: Transperineal ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Spondylolisthesis
Interventions: DEVICE: Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules|OTHER: Iliac crest autograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Synergistic Effects of AIH and FES in Persons With MS
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive
Interventions: OTHER: Acute Intermittent Hypoxia|OTHER: Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Major Depressive Disorder|tACS
Interventions: DEVICE: Closed-loop tACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Fully Covered Metal Stents and Plastic Stents in Preoperative Biliary Drainage
Status: COMPLETED
Conditions: Periampullary Cancer|Complications of Surgical Procedures or Medical Care|Disorder of Bile Duct Stent
Interventions: DEVICE: Fully covered metal stents|DEVICE: Plastic stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance of AIR OPTIX® COLORS
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lotrafilcon B contact lens|DEVICE: Lotrafilcon B contact lens with color|DEVICE: Phemfilcon A contact lens with color
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Learn About the Effects of Multiple Doses of Sisunatovir on People With Respiratory Syncytial Virus (RSV) Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: RV521|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Papilla Index Around Immediate Mandibular Molar Implants Using Customized Healing Abutment Versus Submerged Healing
Status: UNKNOWN
Conditions: Immediate Dental Implant
Interventions: PROCEDURE: Immediate molar implant with customized healing abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease (ENGAGE)
Status: COMPLETED
Conditions: Gaucher Disease, Type 1
Interventions: DRUG: Eliglustat tartrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematic Team Approach to Guide Early Mobilization in Surgical Intensive Care Unit Patients
Status: UNKNOWN
Conditions: Muscle Weakness|Critical Illness|Respiratory Insufficiency
Interventions: PROCEDURE: SOMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SARS-CoV-2 Immune Responses After COVID-19 Therapy and Subsequent Vaccine
Status: COMPLETED
Conditions: Covid19|SARS-CoV2 Infection
Interventions: BIOLOGICAL: Study-provided Moderna mRNA-1273 COVID-19 vaccine|BIOLOGICAL: Community-provided Moderna mRNA-1273 COVID-19 Vaccine|BIOLOGICAL: Community-Provided Pfizer-BioNTech BNT162b2 COVID-19 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Restoration of Permanent Molars Affected With (MIH) Using Composite Restorations or Preformed Metal Crowns
Status: UNKNOWN
Conditions: Molar Incisor Hypomineralization
Interventions: PROCEDURE: Preformed stainless steal crown cemented by glass ionomer lutting cement (Ketac cem,3M Espe)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a New Growing-up Milk on Growth and Nutrient Adequacy in Children With Picky-eating Behaviors
Status: COMPLETED
Conditions: Picky Eating Behaviors
Interventions: DIETARY_SUPPLEMENT: nutrition counseling plus oral milk-based nutritional supplement|OTHER: nutritional counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: D-serine for the Schizophrenia Prodrome
Status: COMPLETED
Conditions: Schizophrenia Prodrome
Interventions: DRUG: D-serine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3-Dimensional Shoulder Complex Pain Alignment (3-D SPA) Mobilization on Frozen Shoulder.
Status: RECRUITING
Conditions: Frozen Shoulder
Interventions: OTHER: 3 D SPA (shoulder complex pain alignment) Moblization|OTHER: Shoulder Moblization (KaltenBorn)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: intrathecal administration of autologous MSC-NP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery
Status: TERMINATED
Conditions: Shoulder Pain
Interventions: PROCEDURE: Superficial Cervical Plexus Block|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Epinephrine in Endotoxemia in Normal Volunteers
Status: COMPLETED
Conditions: Immune System
Interventions: BIOLOGICAL: Endotoxin, Lipopolysaccharide, LPS|BIOLOGICAL: Endotoxin, Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effect of Monolayer Versus Multilayer Leucocyte-Platelet Rich Fibrin (L-PRF) in Interdental Papillary Reconstruction
Status: COMPLETED
Conditions: Recession
Interventions: PROCEDURE: interdental papilla reconstruction with L-PRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Soft Tissue Mobilization of Neck Muscles in Individuals With Myogenous Temporomandibular Disorders: Muscle Energy Technique and Strain-counterstrain
Status: COMPLETED
Conditions: Myogenous Temporomandibular Disorders (mTMD)
Interventions: BEHAVIORAL: Muscle energy technique (MET)|BEHAVIORAL: Strain-counterstrain (SCS)|BEHAVIORAL: sham SCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Energy Drinks and Panax Ginseng on Heart Rhythm
Status: UNKNOWN
Conditions: Electrical Alternation of Heart|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: Energy Drink|DIETARY_SUPPLEMENT: Panax Ginseng|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects
Status: COMPLETED
Conditions: Pseudomonas Aeruginosa
Interventions: DRUG: MEDI3902|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: E7050 in Combination With Cisplatin and Capecitabine Versus Cisplatin and Capecitabine Alone in Patients With Advanced or Metastatic Solid Tumors and Previously Untreated Gastric Cancer
Status: TERMINATED
Conditions: Advanced or Metastatic Solid Tumors|Previously Untreated Gastric Cancer
Interventions: DRUG: E7050|DRUG: cisplatin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minocycline and Tobacco Craving in Smokers With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Tobacco Use
Interventions: DRUG: Minocycline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Eighteen-month Orthodontic Bracket Survival Rate With the Conventional Bonding Technique Versus RMGIC and V-prep
Status: COMPLETED
Conditions: Dental Malocclusion
Interventions: COMBINATION_PRODUCT: v-prep combined with RMGIC for bracket bonding|COMBINATION_PRODUCT: Conventional bracket bonding technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Market Clinical Follow-up of WOVEX (Wovex® Polyester Vascular Prostheses) Bifurcated Prostheses From LEMAITRE VASCULAR Society in the Treatment of Aneurysms or Occlusive Diseases of the Abdominal Aorta.
Status: COMPLETED
Conditions: Aneurysms or Occlusive Disease of the Abdominal Aorta
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Central Venous Catheterization: Seldinger vs. Modified Seldinger Technique
Status: COMPLETED
Conditions: Catheterization, Central Venous
Interventions: OTHER: Modified Seldinger technique, Experienced group|OTHER: Seldinger technique, Experienced group|OTHER: Modified Seldinger technique, Inexperienced group|OTHER: Seldinger technique, Inexperienced group|OTHER: Long-axis technique|OTHER: Short-axis technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: everolimus|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of 3% Cannabidiol (CBD) Cream in Patients With Epidermolysis Bullosa: A Phase II/III Trial
Status: WITHDRAWN
Conditions: Epidermolysis Bullosa|Pain|Itch
Interventions: DRUG: AVCN583601 (3% Cannabidiol cream)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Fecal Microbiota Transplantation in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO)
Status: COMPLETED
Conditions: Small Intestinal Bacterial Overgrowth|Fecal Microbiota Transplantation
Interventions: PROCEDURE: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Compression Is Life In Cardiac Arrest - Quality Study (CILICA-QS)
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: CPRmeter (feedback device) with feedback|DEVICE: CPRmeter (feedback device) without feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Prospective Multicentric Study Comparing the Acute Hemodynamic Effect of Three Modes of Stimulation in Cardiac Resynchronization Therapy Recipients
Status: TERMINATED
Conditions: Heart Failure|Cardiac Resynchronization Therapy
Interventions: OTHER: Device programming of ABBOTT CRT pacemaker or defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Long-term Study to Evaluate Safety and Maintenance of Treatment Effect of LY3074828 in Participants With Moderate-to-Severe Plaque Psoriasis (OASIS-3)
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Mirikizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Teleradiology Program for Frail Patients Living at Home or in Nursing-homes
Status: COMPLETED
Conditions: Telemedicine|Teleradiology|Cost-Benefit Analysis|Frail Elderly
Interventions: OTHER: Teleradiology Service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Comparing a Generic Diclofenac Sodium Topical Gel, 1% to Voltaren in the Treatment of Subjects With Osteoarthritis of the Knee
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Diclofenac Sodium Topical Gel, 1%|DRUG: Voltaren Topical Gel, 1%|DRUG: Vehicle Diclofenac Sodium Topical Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose
Status: UNKNOWN
Conditions: Rabies
Interventions: BIOLOGICAL: Rabies vaccine, manufactured by ChengDa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors
Status: COMPLETED
Conditions: Adult B Acute Lymphoblastic Leukemia|Adult Nasal Type Extranodal NK/T-Cell Lymphoma|Adult Solid Neoplasm|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-Cell Lymphoma|Chronic Lymphocytic Leukemia|Cutaneous B-Cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Hepatosplenic T-Cell Lymphoma|Intraocular Lymphoma|Lymphomatous Involvement of Non-Cutaneous Extranodal Site|Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Nodal Marginal Zone Lymphoma|Recurrent Adult Acute Lymphoblastic Leukemia|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-Cell Leukemia/Lymphoma|Recurrent Cutaneous T-Cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides and Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Refractory Plasma Cell Myeloma|Small Intestinal Lymphoma|Splenic Marginal Zone Lymphoma|Testicular Lymphoma|Waldenstrom Macroglobulinemia
Interventions: DRUG: Bendamustine Hydrochloride|OTHER: Pharmacological Study|BIOLOGICAL: Rituximab|DRUG: Veliparib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Modified Oxygen Mask Associated to Nasal Prongs During a High Flow Oxygenation Method
Status: COMPLETED
Conditions: Oxygen Inhalation Therapy
Interventions: DEVICE: Double trunk mask add above a nasal canulae
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A TSHRN1201 Sub-study-To Evaluate the Effects of add-on Ranolazine on Exercise Tolerance and Angina Frequency
Status: COMPLETED
Conditions: Angina
Interventions: DRUG: Ranolazine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study Using GSK573719 And Tiotropium In Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Effect of LIMICOL and Physical Activity on LDL Cholesterol and Muscle Function.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: LIMICOL|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: PCI with implantation with DES
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Tranexamic Acid Versus Vaginal Dinoprostone in Abdominal Myomectomy
Status: UNKNOWN
Conditions: Myomectomy
Interventions: DRUG: intravenous tranexamic acid|DRUG: vaginal dinoprostone|DRUG: vaginal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients
Status: RECRUITING
Conditions: Breast Neoplasms|Mastectomy|Nerve Block|Dexmedetomidine|Pain, Postoperative|Chronic Pain|Prognosis
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Two Toric Soft Contact Lenses
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: Lens A (ocufilcon D)|DEVICE: Lens B (fanfilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of Furmonertinib for EGFR Mutation-positive NSCLC Patients With Brain Metastasis
Status: RECRUITING
Conditions: EGF-R Positive Non-Small Cell Lung Cancer|CNS Metastases
Interventions: DRUG: Furmonertinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p