pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: 2-arm Parallel Group Study of Fixed Combination of CHF 5993 vs Ultibro® in COPD Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: CHF 5993 + Ultibro matched placebo|DRUG: Ultibro + CHF 5993 matched placebo|PROCEDURE: Central spirometry|OTHER: COPD assessment test|PROCEDURE: Local laboratory Assessments|OTHER: Saint George's Respiratory Questionnaire|OTHER: EXACT-pro questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Glutaraldehyde on Dentin Hypersensitivity After Non-surgical Periodontal Treatment
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Placebo gel|OTHER: Placebo Gel + 5% Glutaraldehyde Aqueous Solution|OTHER: Phosphoric Acid 37% + Solução aquosa de glutaraldeído a 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Abdominal Massage on Pain and Distention After Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Pain, Abdominal|Massage|Distension; Bowel|Patients Care|Nursing
Interventions: OTHER: Abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease|Coronary Stenosis
Interventions: DEVICE: Rapamycin target eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acids Enriched Food and Microvascular Reactivity
Status: UNKNOWN
Conditions: Omega-3 Polyunsaturated Fatty Acids
Interventions: DIETARY_SUPPLEMENT: Omega-3 chicken eggs|DIETARY_SUPPLEMENT: Regular chicken eggs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy of Accelerated Versus Standard Regiment of Hepatitis B Virus Vaccine Among Inflammatory Bowel Disease Patients
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: BIOLOGICAL: standard hepatitis B vaccine|BIOLOGICAL: accelerated HBV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Dietary Soy Protein on Facial Wrinkles in Postmenopausal Women
Status: UNKNOWN
Conditions: Photoaging
Interventions: DIETARY_SUPPLEMENT: Soy protein|DIETARY_SUPPLEMENT: Casein protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of OROS® Oxybutynin to That of Ditropan® (Immediate-release Oxybutynin) for the Treatment of Patients With Urge or Mixed Urinary Incontinence.
Status: COMPLETED
Conditions: Urge Incontinence
Interventions: DRUG: OROS® oxybutynin or Ditropan®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Stage IIB Prostate Cancer|Stage III Prostate Cancer|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: anti-PSMA monoclonal antibody MDX1201-A488|PROCEDURE: robot-assisted laparoscopic surgery|OTHER: diffuse optical imaging|OTHER: pharmacological study|OTHER: Laboratory Biomarker|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Islet Transplantation Using Abatacept
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Efalizumab|DRUG: Abatacept|DRUG: Belatacept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy Plus Monoclonal Antibody Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: agatolimod sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of CUDC-907 in Patients With RR DLBCL, Including Patients With MYC Alterations
Status: COMPLETED
Conditions: Relapsed and/or Refractory Diffuse Large B-cell Lymphoma Including With Myc Alterations
Interventions: DRUG: CUDC-907
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D vs 2D-laparoscopy for Rectocele and Rectal Prolapse Correction: a Prospective, Randomized, Single Center Study
Status: UNKNOWN
Conditions: Rectocele; Female|Rectocele and Incomplete Uterine Prolapse|Rectocele and Complete Uterovaginal Prolapse|Rectal Prolapse
Interventions: PROCEDURE: Laparoscopic ventral mesh rectopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I FOLFOX Combination
Status: COMPLETED
Conditions: Advanced Colorectal Carcinoma
Interventions: DRUG: ZD6474 (vandetanib)|DRUG: 5-Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-Market Clinical Follow-up Investigation to Verify Performance and Safety of Viiral®Nasal Spray in Subjects With Dry Nose Symptoms
Status: COMPLETED
Conditions: Rhinitis Sicca
Interventions: DEVICE: Sialic acid nasal spray|DEVICE: Isotonic Saline Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Gastric Tube on the Quality of Life and Nutritional Status After Ivor-Lewis Esophagectomy
Status: TERMINATED
Conditions: Oesophageal Cancer
Interventions: PROCEDURE: gastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Power Short-Duration Radiofrequency Ablation in Patients With Typical Atrial Flutter
Status: RECRUITING
Conditions: Typical Atrial Flutter|Catheter Ablation
Interventions: PROCEDURE: Conventional cavotricuspid isthmus ablation|PROCEDURE: High-power short-duration ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter
Status: WITHDRAWN
Conditions: Typical Atrial Flutter|Risk Factors With Future Development of Atrial Flutter
Interventions: PROCEDURE: CTI ablation alone|PROCEDURE: CTI ablation and Pulmonary vein isolation (PVI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Juvenile Justice Translational Research on Interventions for Adolescents in the Legal System
Status: COMPLETED
Conditions: Substance Use Disorders
Interventions: BEHAVIORAL: Core|BEHAVIORAL: Enhanced
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Assessing the Effectiveness of an N-of-1 Platform Using Study of Cognitive Enhancers
Status: TERMINATED
Conditions: Cognitive Performance
Interventions: DRUG: L-theanine|DIETARY_SUPPLEMENT: Caffeine supplement|DEVICE: N1 app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Ketones Influence on Glucose Metabolism in Brain. A Human Positron Emission Tomography (PET) Study
Status: COMPLETED
Conditions: Ketone Body Metabolism|Brain Metabolism
Interventions: DRUG: ketone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PA32540 or Enteric Coated Aspirin 325 mg in Subjects Who Are at Risk for Developing Aspirin-Associated Ulcers
Status: COMPLETED
Conditions: Gastric Ulcer
Interventions: DRUG: PA32540|DRUG: EC Aspirin 325
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder
Status: RECRUITING
Conditions: Bipolar Disorder|Mood Swing|Prodromal Symptoms
Interventions: BEHAVIORAL: Bright light therapy + Psycho-education + Imagery focused Cognitive Therapy|BEHAVIORAL: Blue-light blocking glasses + Psycho-education + Imagery focused Cognitive Therapy|BEHAVIORAL: Psycho-education + Imagery focused Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Diverting Ileostomy Necessary in Stapled Ileoanal Pouch?
Status: COMPLETED
Conditions: Ulcerative Colitis|Familial Adenomatous Polyposis
Interventions: PROCEDURE: adding diverting ileostomy|PROCEDURE: omitting diverting ileostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Influence of Transcranial Direct Current Stimulation of the Primary Motor Cortex on Pain Sensation in Patients Suffering From Fibromyalgia Syndrome
Status: TERMINATED
Conditions: Fibromyalgia
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Effects of Ketamine and Remifentanil on Serum Cystatin-c Levels in CABG Surgery
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: remifentanil|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Factors Associated With Mortality, Morbidity and Prognosis in Dementia Patients
Status: COMPLETED
Conditions: Dementia|Dementia, Vascular|Dementia With Lewy Bodies|Dementia of Alzheimer Type|Dementia Frontal|Dementia, Mixed
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Psychological Impact of Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation on Donors
Status: RECRUITING
Conditions: Haplo-identical Transplantation|Transplantation
Interventions: OTHER: Evaluate the evolution of the psychic state of the donors (ascendants and descendants), by means of questionnaires, within the framework of haplo-identical allograft.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Effect of Individualizing Daytrana Wear-times on Sleep in Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|INSOMNIA
Interventions: DRUG: Daytrana|DRUG: Daytrana|DRUG: Daytrana|DRUG: Daytrana
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: IVUS-guided DK Crush Stenting Technique for Patients With Complex Bifurcation Lesions
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate
Status: COMPLETED
Conditions: Vitamin B12 Deficiency
Interventions: DIETARY_SUPPLEMENT: L-5-methyltetrahydrofolate (Metafolin ®)|DIETARY_SUPPLEMENT: folic acid|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand
Status: COMPLETED
Conditions: Corneal Staining
Interventions: OTHER: Multipurpose Solution #1|OTHER: Multipurpose Solution #2|OTHER: Mutlipurpose Solution #3|OTHER: Multipurpose Solution #4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Assess AFM24 in Advanced Solid Cancers
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: 14 mg AFM24|DRUG: 40 mg AFM24|DRUG: 80 mg AFM24|DRUG: 160 mg AFM24|DRUG: 320 mg AFM24|DRUG: 480 mg AFM24|DRUG: 720 mg AFM24
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chama Cha MamaToto: a Pilot Study of Peer Support Groups in Kenya
Status: COMPLETED
Conditions: Pregnancy Related|Group, Peer
Interventions: BEHAVIORAL: Chama cha Mamtoto
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Low-Dose Adjunctive Aripiprazole in the Treatment of Bipolar Depression: Double-Blind Placebo-Controlled Pilot Study
Status: TERMINATED
Conditions: Bipolar Disorder|Depressive Episode
Interventions: DRUG: Low dose Adjunctive Aripiprazole|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effects of a Dietary Supplement on Cognitive Performance in Highly Trained Athletes.
Status: COMPLETED
Conditions: Reaction Time
Interventions: DIETARY_SUPPLEMENT: Treatment (CopaPrime+ (USANA Health Sciences)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Shortwave Diathermy Versus Ultrasound Waves on Increasing ROM and Decreasing Pain After Extensor Tendon Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensor Tendon Reconstruction
Interventions: DEVICE: shortwave diathermy|DEVICE: ultrasound waves|OTHER: traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Changes in the Signalling Pathways During Spinal Cord Injury-induced Skeletal Muscle Atrophy
Status: UNKNOWN
Conditions: Spinal Cord Injuries|Muscle Atrophy
Interventions: PROCEDURE: Motionmaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Omnidirectional Virtual Reality and Treadmill Training for Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: Omnidirectional Virtual Reality and Treadmill Training|BEHAVIORAL: Traditional Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Target Engagement of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Eating Disorder
Interventions: BEHAVIORAL: Counter Attitudinal Therapy|BEHAVIORAL: Interpersonal Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SecOnd-generation seLf-expandable Versus Balloon-expandable Valves and gEneral Versus Local Anesthesia in TAVI
Status: UNKNOWN
Conditions: Aortic Stenosis
Interventions: DEVICE: CoreValve Evolut R|DEVICE: Edwards Sapien 3|PROCEDURE: Local anesthesia with conscious sedation|PROCEDURE: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG)
Status: TERMINATED
Conditions: Diffuse Intrinsic Pontine Glioma
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib|DRUG: Temozolomide|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Therapeutic Targets of Accelerated Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia|Diabetes Mellitus|Aging
Interventions: BEHAVIORAL: Resistance exercise training|BEHAVIORAL: Bed rest|BEHAVIORAL: Intensive physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Compare the Uptake Into the Blood of Two Strengths of Somapacitan After Injection Under the Skin in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Growth Hormone Deficiency
Interventions: DRUG: somapacitan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Oncology|Non-Small Cell Lung Cancer
Interventions: DRUG: AMG 954/Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraduodenal Aspiration Study to Assess the Bioavailability of Oral Pancrecarb® Compared to Placebo Control
Status: TERMINATED
Conditions: Exocrine Pancreatic Insufficiency|Chronic Pancreatitis|Cystic Fibrosis
Interventions: DRUG: Pancrelipase
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Licartin for Preventing Tumor Recurrence After Liver Resection
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Licartin (generic name,[131I]metuximab injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)
Status: COMPLETED
Conditions: Mood|Stress, Psychological
Interventions: BEHAVIORAL: From Cancer to Health (C2H-D)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating an Intervention to Increase Use of Call Centre Support for Self-managed Medical Abortion
Status: UNKNOWN
Conditions: Abortion, Drug-Induced|Pharmacies
Interventions: BEHAVIORAL: Pharmacy encouraged to promote call centre use to clients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Medication Treatment for Opioid Use Disorder in Expectant Mothers
Status: ACTIVE_NOT_RECRUITING
Conditions: Opioid-Related Disorders|Drug Addiction|Pregnancy Related|Substance Abuse|Drug Abuse|Neonatal Abstinence Syndrome|Neonatal Opioid Withdrawal Syndrome|Drug Abuse in Pregnancy
Interventions: DRUG: Buprenorphine Injection|DRUG: Buprenorphine Sublingual Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Supraventricular Tachycardia in Patients With Non-cardiac Surgery by Dexmedetomidine
Status: UNKNOWN
Conditions: Perioperative Period
Interventions: DRUG: Dexmedetomidine; Midazolam;
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraligamental Local Anesthesia Versus Infiltration Technique for Extraction of Grade II Mobility Maxillary Molars
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: PROCEDURE: Intraligamental local anesthetic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of Inspiratory Muscle Training and Baduanjin Exercises in Hypertrophic Cardiomyopathy Patients
Status: NOT_YET_RECRUITING
Conditions: Hypertrophic Cardiomyopathy|Heart Diseases
Interventions: OTHER: Inspiratory Muscle Training|OTHER: Baduanjin Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Cardiovascular Morbi-mortality by Sildenafil in Patients With Arterial Claudication
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant and Adjuvant Durvalumab in Combination With Neoadjuvant Chemotherapy in Patients With Operable Urothelial Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Cancer
Interventions: DRUG: Neoadjuvant and adjuvant durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccination With GM-K562 Cells in Patients With Advanced Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) After Allogeneic Hematopoetic Stem Cell Transplantation
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome-Refractory Anemia With Excess Blasts
Interventions: BIOLOGICAL: GM-K562/leukemia cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple-Centered, Prospective Cohort Study: the Second Prevention Trial for Ischemic Stroke With Deng Zhan Sheng Mai Capsule（SPIRIT-DZSM-2）
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: :Deng Zhan Sheng Mai Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: VT-EBV-N for Treatment of Severe in EBV Positive Extranodal NK/T Cell Lymphoma Patients
Status: UNKNOWN
Conditions: Extranodal NK/T-cell Lymphoma
Interventions: BIOLOGICAL: VT-EBV-N|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study on Effects of Uniportal VATS Versus Triportal VATS
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: VATS uni-portal lobectomy and lymphoadenectomy|PROCEDURE: VATS three-portal lobectomy and lymphoadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Evaluation of T.R.U.E. TEST® Panel 3.2 Allergens: Dose Response
Status: COMPLETED
Conditions: Contact Dermatitis
Interventions: BIOLOGICAL: T.R.U.E. TEST® Skin Patch Test: Dose Response Allergens
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Kneehab in Strengthening the Quadriceps of Patients Post Anterior Cruciate Ligament (ACL) Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DEVICE: Kneehab|DEVICE: Poli-Stim|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Bilateral Uterine Artery Ligation and Bakri Balloon During Cesarean Section
Status: UNKNOWN
Conditions: Placenta Previa
Interventions: DEVICE: Bakri balloon|PROCEDURE: Bilateral Uterine Artery Ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Lactobacillus Reuteri DSM 17938 for the Treatment of Acute Gastroenteritis in Children
Status: COMPLETED
Conditions: Acute Gastroenteritis
Interventions: DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: cetuximab|DRUG: FOLFOX or|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Age-related Macular Degeneration Treatments Trials: Lucentis-Avastin Trial
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: ranibizumab|DRUG: bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection
Status: RECRUITING
Conditions: Thoracic Surgery|Video-Assisted|Cryotherapy Effect|Paravertebral Block
Interventions: PROCEDURE: Cryoanalgesia AND single-injection paravertebral block|PROCEDURE: Single-injection paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Study to Evaluate the Effect of Rifampin on the Singe Dose of Experimental Medication BMS-986224 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Rifampin|DRUG: BMS-986224
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness of the Web-Based Monitoring Program Given to Mothers of Premature Babies
Status: ACTIVE_NOT_RECRUITING
Conditions: Infant Development|Maternal Stress|Growth
Interventions: OTHER: Web-Based Monitoring Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Childhood and Adolescent Essential Thrombocythemia
Status: RECRUITING
Conditions: Essential Thrombocytopenia
Interventions: DRUG: Recombinant Interferon Alpha|DRUG: Pegylated interferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab Regimen Evaluation in Colorectal Cancer to Estimate Primary Response to Treatment
Status: COMPLETED
Conditions: Colon Cancer|Colorectal Cancer|Rectal Cancer|Cancer|Metastatic Cancer|Metastatic Colorectal Cancer|Oncology
Interventions: BIOLOGICAL: Panitumumab|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia|Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Xocai Activ drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of 3 Different Models of MNT on DM Control in Overweight Patients With T2DM
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: BEHAVIORAL: Traditional MNT|BEHAVIORAL: Structured MNT|BEHAVIORAL: Structured MNT plus Weekly Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetrorelix (CET) Pamoate Regimens in Patients With Symptomatic Benign Prostatic Hypertrophy (BPH)
Status: TERMINATED
Conditions: Benign Prostatic Hypertrophy
Interventions: DRUG: Cetrorelix 78 mg + 78 mg|DRUG: Cetrorelix 78 mg + 52 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of the Impact of Body Scanning and Intensive Behavioral Intervention on Behavioral Change and Health Outcomes
Status: COMPLETED
Conditions: Coronary Disease|Behavior and Behavior Mechanisms|Hypertension|Hypercholesterolemia
Interventions: BEHAVIORAL: Physician Body Scan Consultation with Behavioral Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Airway Inflammation in Congenital Diaphragmatic Hernia Patients
Status: COMPLETED
Conditions: Congenital Diaphragmatic Hernia
Interventions: DRUG: Hypersaline|DRUG: Bronchodilator Response
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma
Status: RECRUITING
Conditions: Hodgkin Lymphoma|Relapsed or Refractory Hodgkin Lymphoma
Interventions: DRUG: pembrolizumab|DRUG: gemcitabine|DRUG: vinorelbine|DRUG: liposomal doxorubicin|PROCEDURE: Stem cell mobilization and collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Diterpene Ginkgolides Meglumine Injection in Elderly Patients With Ischemic Stroke
Status: COMPLETED
Conditions: Stroke|Ischemic Stroke|Nervous System Diseases|Cerebral Infarction|Brain Ischemia|Brain Infarction
Interventions: DRUG: Diterpene ginkgolides meglumine injection|DRUG: Ginaton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Stromal Changes After PRK by Using Intraoperative Mitomicin C
Status: TERMINATED
Conditions: Refractive Disorders
Interventions: DRUG: Mitomycin C and Photorefractive keratectomy (PRK)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B|Mother-to-Child Transmission|Safety|Efficacy|Hepatitis B Virus|Tenofovir Alafenamide Fumarate
Interventions: DRUG: Tenofovir Alafenamide fumarate 25mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor|Metastatic Solid Tumor
Interventions: DRUG: JZP898|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROfylactic Haloperidol in Patients Defined as High Risk for DElirium With Delirium Risk mOdel
Status: UNKNOWN
Conditions: Delirium
Interventions: DRUG: Haloperidol|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
Status: COMPLETED
Conditions: Pneumonia|Primary Health Care|Child Health|Hypoxia|Referral and Consultation|Decision Support Systems, Clinical|Oxymetry
Interventions: DEVICE: Pulse oximetry|DEVICE: Clinical Decision Support Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL：a Multicenter Phase Ib/II Stuty
Status: UNKNOWN
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Methotrexate|DRUG: Rituximab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of 81 vs 325mg of ASA in Treatment of BCVI
Status: NOT_YET_RECRUITING
Conditions: Carotid Artery Injuries|Traumatic Injury|Vertebral Artery Injury
Interventions: DRUG: Acetylsalicylic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Low Dose Versus Usual Dose Dexamethasone for Symptom Control in Children Undergoing Cranial or Craniospinal Radiation
Status: TERMINATED
Conditions: Vomiting|Headache
Interventions: DRUG: High dose dexamethasone|DRUG: Low dose dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Alisporivir (Deb025) and Boceprevir Triple Therapies in African American Participants Not Previously Treated for Chronic Hepatitis C Genotype 1
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Alisporivir|DRUG: Boceprevir|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Diclofenac DDEA 2.32 % in Patient Suffering From Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: diclofenac diethylamine, DDEA 2.32% gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Neoadjuvant Docetaxel ± Metronomic Capecitabine/CTX Followed by FEC in Women With Operable Triple Negative Breast Cancer
Status: SUSPENDED
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel|DRUG: Capecitabine|DRUG: Cyclophosphamide (tablet)|DRUG: Fluorouracil|DRUG: Epirubicin|DRUG: Cyclophosphamide (injection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Eldecalcitol Soft Capsule in Healthy Chinese Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: reference eldecalcitol soft capsule|DRUG: test eldecalcitol soft capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intensive Referral to Reduce Smoking in Probationers
Status: COMPLETED
Conditions: Smoking Cessation|Substance Use Disorder
Interventions: BEHAVIORAL: Intensive Referral Intervention Group|BEHAVIORAL: Standard Practice Facilitated Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Study of Subcutaneously Administered JNJ-75220795
Status: COMPLETED
Conditions: Fatty Liver Disease
Interventions: DRUG: JNJ-75220795|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Starting Granulocyte Colony-Stimulating Factor at 1 Day vs 3 Days Following Chemotherapy in Pediatric Cancer Patients
Status: UNKNOWN
Conditions: Granulocyte Colony-Stimulating Factor|Chemotherapy-induced Neutropenia|Chemotherapy-Induced Febrile Neutropenia|Pediatric Cancer
Interventions: DRUG: Granulocyte Colony-Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Pioglitazone on HIV-1 Related Lipoatrophy: a Randomized, Double Blind, Placebo-Controlled Trial in 130 Patients
Status: TERMINATED
Conditions: HIV-Associated Lipodystrophy Syndrome|HIV Infections
Interventions: DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Cold Snare Polypectomy Versus Hot Snare Polypectomy for Resection of Small Pedunculated Colorectal Polyps：a Randomized Controlled Trial
Status: RECRUITING
Conditions: Pedunculated Colorectal Polyps|Haemorrhage
Interventions: OTHER: cold snare polypectomy|OTHER: hot snare polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community Setting
Status: COMPLETED
Conditions: Nervous System Diseases
Interventions: DRUG: SHP615|DRUG: MHOS/SHP615
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Tocilizumab for the Treatment of Patients With Relapsed or Refractory t(11;14) Multiple Myeloma
Status: RECRUITING
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: BIOLOGICAL: Tocilizumab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulating Speech Perception With Current Stimulation
Status: RECRUITING
Conditions: Healthy
Interventions: PROCEDURE: transcranial alternating current stimulation (tACS)|PROCEDURE: electroencephalography (EEG)|PROCEDURE: brain imaging (fMRI)|PROCEDURE: electroencephalography (EEG) with neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hysteroscopic Metroplasty in Unexplained Infertile Women With Dysmorphic Uterus
Status: UNKNOWN
Conditions: Hysteroscopy|Pregnancy Rate|Abortion|Ectopic Pregnancy|Intrauterine Insemination
Interventions: PROCEDURE: office hysteroscopic metroplasty intervention arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Retrovertion Assesment and Study in Elderly Patients With Reverse Total Shoulder Arthroplasty
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rotator Cuff Tear Arthropathy
Interventions: PROCEDURE: humeral retroversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations
Status: RECRUITING
Conditions: Progression of Rheumatoid Arthritis|Osteoarthritis of Multiple Joints
Interventions: PROCEDURE: The examinations for bones in joints of OA and RA patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Neurovascular Transduction During Exercise in Chronic Kidney Disease
Status: RECRUITING
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: 6R-BH4|OTHER: 6R-BH4 placebo|DIETARY_SUPPLEMENT: Folic acid|OTHER: Exercise training|OTHER: Stretching|DIETARY_SUPPLEMENT: Histidine and beta-alanine supplementation|OTHER: Histidine and beta-alanine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Rhinosinusitis|Chronic Eosinophilic Rhinosinusitis|Allergic Rhinosinusitis
Interventions: DRUG: Budesonide|DRUG: Saline alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of LLLT and Ozone to Reduce Complications After Extraction of Impacted Lower Molar
Status: COMPLETED
Conditions: Complications of Extraction of Impacted Teeth
Interventions: RADIATION: low level laser therapy|DRUG: ozone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Dark Chocolate and Platelet Function in Humans
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Dark chocolate enriched in flavan-3-ols and procyanidins|DIETARY_SUPPLEMENT: Standard dark chocolate|DIETARY_SUPPLEMENT: White chocolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clamping the Double Lumen Tube
Status: COMPLETED
Conditions: One-lung Ventilation
Interventions: DEVICE: Clamping the Double Lumen Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of a Robotic Distal Gastrectomy on Non-inferiority of N2 Area Nodal Dissection
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: Distal Gastrectomy with D2 LND
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children (DINISAS)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: OTHER: Home Respiratory Polygraphy (HRP)|OTHER: Standard Polysomnography (PSG)|OTHER: Home Respiratory Polygraphy (HRP)|OTHER: Standard Polysomnography (PSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Atypical MOLes and Melanoma Early Detection Study (MoleMed)
Status: UNKNOWN
Conditions: Melanoma|Melanoma (Skin)|Moles|Nevus|Nevus, Blue|Nevus, Pigmented|Nevus, Spitz|Nevi, Spindle Cell|Nevi, Dysplastic|Dysplastic Nevus Syndrome|Mucosal Melanoma|Mucosal Melanosis
Interventions: PROCEDURE: Non-invasive adhesive system (patch)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Post-operative Pain After Different Instrumentation Techniques in Pulpectomy Treatment of Primary Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulp Necroses
Interventions: PROCEDURE: pulpectomy treatment will be done using the adaptive xp endo shaper.|PROCEDURE: pulpectomy treatment will be done using FANTA AF baby files.|PROCEDURE: pulpectomy treatment will be done using hand k files.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of PfSPZ Vaccine in an Age De-escalation Trial in Equatorial Guinea.
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|BIOLOGICAL: PfSPZ Challenge (for CHMI)|OTHER: Normal Saline|BIOLOGICAL: PfSPZ Challenge (for PfSPZ-CVac)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 5HT3 Antagonism and Auditory Gating in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ondansetron|BEHAVIORAL: neuropsychological testing|DRUG: nicotine|DRUG: haloperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of the "Kid'EM App" Digital Guidance Tool for Setting Rehabilitation Goals by the Rehabilitation Professional for Children With Chronic Conditions Impacting Physical Health (READ'APP'T)
Status: NOT_YET_RECRUITING
Conditions: Children With Chronic Illnesses Affecting Physical Health
Interventions: OTHER: Kid'EM app" experimental group|OTHER: Kid'EM app control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study to Compare Two Minoxidil Formulations on Women With Androgenetic Alopecia
Status: COMPLETED
Conditions: Androgenetic Alopecia|Female Pattern Hair Loss
Interventions: DRUG: minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Outcomes After Positive Intraoperative Messages
Status: TERMINATED
Conditions: Postoperative Pain|Postoperative Nausea|Postoperative Vomiting
Interventions: BEHAVIORAL: Intraoperative positive messages|BEHAVIORAL: Intraoperative positive messages|BEHAVIORAL: No message
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome|Keratoconjunctivitis Sicca
Interventions: DRUG: 0.05% Voclosporin Ophthalmic Solution (VOS)|DRUG: 0.10% VOS|DRUG: 0.20% VOS|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT