pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison Between Cervical Tourniquet and Uterine Artery Ligation Prior to Segmental Resection Approach
Status: NOT_YET_RECRUITING
Conditions: Placenta Accreta Spectrum
Interventions: PROCEDURE: cervical tourniquet|PROCEDURE: uterine artery ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Mycobacterium Avium Complex Infection|Bronchiectasis|Lung Diseases
Interventions: DRUG: RHB-204|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum GPER-1 and Oxidant/Antioxidant Levels on Retinopathy in Diabetic Patients
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetic Retinopathy|Hormones
Interventions: DIAGNOSTIC_TEST: The effect of GPER-1 on the formation of diabetic retinopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Drug-drug Interaction Effect of Rifampin on the Pharmacokinetics of AMG 510 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AMG 510|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP)
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy
Interventions: DIETARY_SUPPLEMENT: Coenzyme Q10|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BI 836858 Dose Escalation in Patients With Refractory or Relapsed Acute Myeloid Leukemia and in Patients in Complete Remission With High Risk to Relapse
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: BI 836858
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Repair of Cesarean Scar Niche
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: laparoscopic repair|DRUG: medical treatment in the form of combined hormonal contraception
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: NEURoaid II (MLC 901) Assessment in Cognitively Impaired Not Demented Subjects
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: DRUG: MLC901|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries
Status: UNKNOWN
Conditions: Endothelial Dysfunction|Atherosclerosis|Inflammation|Myocardial Ischemia
Interventions: DRUG: Acetylcholine|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
Status: NOT_YET_RECRUITING
Conditions: Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Interventions: DRUG: PF-06821497|DRUG: Docetaxel|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periarticular Injection and Hamstring Block Versus Placebo for Pain Control in Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: COMBINATION_PRODUCT: periarticular infiltration (50ml) with Ropivacaine Hydrochloride 10 MG/ML (200 mg) + ketorolac tromethamine 30 mg/ml (30 mg) + adrenaline 1mg/ml (300 microgram) + morphine hydrochloride 10mg/ml (5 mg)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: End-expiratory Pressure During Laparoscopic Surgery in the Trendelenburg Position by Electrical Impedance Tomography
Status: NOT_YET_RECRUITING
Conditions: Pneumoperitoneum|Trendelenburg Position|Laparoscopic Surgery
Interventions: DEVICE: electrical impedance tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sequencing Mycobacteria and Algorithm-determined Resistant Tuberculosis Treatment Trial
Status: RECRUITING
Conditions: Rifampicin Resistant Tuberculosis|Drug-resistant Tuberculosis|Multidrug Resistant Tuberculosis|Pulmonary Tuberculoses
Interventions: DEVICE: WGS DST strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Absorption, Metabolism, and Excretion and Absolute Bioavailability of Xevinapant in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Radiolabelled Xevinapant 200 mg (Oral Solution)|DRUG: Radiolabelled Xevinapant 100 μg (IV Solution)|DRUG: Xevinapant 200 mg (Oral Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Early Mechanical Ventilation to Severe Acute Pancreatitis
Status: UNKNOWN
Conditions: Acute Pancreatitis|Complication of Ventilation Therapy
Interventions: OTHER: early mechanical Ventilation|OTHER: Conventional Mechanical Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Idelalisib, and Venetoclax in Relapsed/Refractory CLL/SLL
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|CLL|Relapsed CLL|Refractory Chronic Lymphocytic Leukemia|Relapsed Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|SLL|Relapsed Small Lymphocytic Lymphoma|Refractory Small Lymphocytic Lymphoma
Interventions: DRUG: Dose combination 1-1|DRUG: dose combination 1-2|DRUG: Dose combination 1-3|DRUG: dose combination 1-4|DRUG: Sub-Trial: Dose combination 2-1|DRUG: Sub-Trial: Dose combination 2-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Smartphone App Assisted Home Blood Pressure Monitoring Amongst Hypertensive Patients in Singapore
Status: UNKNOWN
Conditions: Hypertension
Interventions: OTHER: Handwritten logbook recording of home blood pressure readings|DEVICE: Smartphone assisted wireless recording of home blood pressure readings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Kinesio Tape on Pain, Muscle Strength, Functionality and Kinesiophobia in Shoulder Impingement Syndrome
Status: NOT_YET_RECRUITING
Conditions: Physiotherapy|Kinesiotaping
Interventions: OTHER: Traditional Physiotherapy + Sham Kinesiotape|OTHER: Kinesiotape with Facilitation Method + Traditional Physiotherapy|OTHER: Kinesiotape with Inhibition Method + Traditional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn Children
Status: COMPLETED
Conditions: Intensive Care Unit Syndrome
Interventions: OTHER: Measure of intravesical pressure|OTHER: Measure of intravesical pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|Hypoglycemia
Interventions: BIOLOGICAL: Allogeneic Islets of Langerhans|DRUG: Everolimus|DRUG: anti-thymocyte globulin|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Isotope Study of an Iron Fatty Acid Complex
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: IFAC|DIETARY_SUPPLEMENT: MIFAC|DIETARY_SUPPLEMENT: Control Ferrous Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Utilization of Simulated Grid (SimGrid™) Technology for the Reduction of Ionizing Radiation Dose on X-ray Examination in Obese Patients
Status: COMPLETED
Conditions: Obesity, Morbid
Interventions: DIAGNOSTIC_TEST: X-ray imaging with physical grid using conventional processing|DIAGNOSTIC_TEST: X-ray imaging without physical grid using conventional processing|DIAGNOSTIC_TEST: X-ray imaging without physical grid using experimental SimGrid offline processing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Follow-up to the Phase 1 Study of Adjuvanted SARS-CoV-2 (SCB 2019) Vaccine for COVID-19.
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: SCB-2019
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Irinotecan in Treating Children With Refractory or Advanced Solid Tumors Who Are Receiving Anticonvulsants
Status: COMPLETED
Conditions: Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Tele-rehabilitation After Anterior Cruciate Ligament Reconstruction
Status: NOT_YET_RECRUITING
Conditions: Tele-rehabilitation|Anterior Cruciate Ligament Reconstruction
Interventions: BEHAVIORAL: Tele-rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CVD Nutrition Modules Tailored to Low Literacy Skills
Status: COMPLETED
Conditions: Cardiovascular Diseases|Heart Diseases
Interventions: BEHAVIORAL: Computer Program Intervention Group|OTHER: Minimal Intervention Group|BEHAVIORAL: Health Counselor Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Nano-X Image Guidance: CBCT With Gravity-induced Motion
Status: NOT_YET_RECRUITING
Conditions: Cancer
Interventions: DEVICE: Nano-X Patient Rotation System|RADIATION: Conventional CBCT scan|OTHER: Psychometrically validated questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Advance Trial. Tongue Advancement for Obstructive Sleep Apnea: An Evaluation of the Aspire Medical Advance System
Status: UNKNOWN
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Aspire Medical Advance System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eribulin Mesylate and Cisplatin in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: eribulin mesylate|DRUG: cisplatin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Classroom Communication Resource (CCR) Intervention to Change Grade 7 Peer's Attitudes Towards Children Who Stutter (CWS)
Status: UNKNOWN
Conditions: Stuttering in Adolescence|Bullying of Child
Interventions: OTHER: Classroom Communication Resource|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation in Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DEVICE: Active - HD tDCS|DEVICE: Sham - HD tDCS|DEVICE: Active - Conventional tDCS|DEVICE: Sham - Conventional tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine Therapy
Status: RECRUITING
Conditions: Locally Advanced Breast Cancer|Hormone Receptor Positive，HER2-negative Breast Cancer
Interventions: DRUG: letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the iFuse Bedrock Technique in Association With Posterior Lumbosacral Fusion With Iliac Fixation.
Status: RECRUITING
Conditions: Sacroiliitis|Sacroiliac; Fusion|Lumbosacral; Fusion|Spine Deformity
Interventions: DEVICE: iFuse Bedrock technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ALLoreactive T-Cell receptOr RePertoire in kidnEy tranSplantation
Status: RECRUITING
Conditions: Renal Transplant Rejection|Immune Repertoire|Transplant; Complication, Rejection|Alloreactivity
Interventions: DIAGNOSTIC_TEST: Mixed lymphocyte reaction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Premedication With Curcumin on Post-endodontic Pain
Status: COMPLETED
Conditions: Acute Pulpitis
Interventions: DRUG: curcumin group:Curcumin is an ancient coloring spice . Interestingly, it has various pharmacological activities including analgesic, anti-inf|DIETARY_SUPPLEMENT: 400mg starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: uPAR PET/CT for Staging Advanced and Localised Oral and Oropharyngeal Cancer
Status: UNKNOWN
Conditions: Oral Cancer|Oropharyngeal Cancer|Neoplasms|Head and Neck Neoplasms|Cancer of Mouth|Neoplasms by Site
Interventions: OTHER: 68Ga-NOTA-AE105 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention
Status: COMPLETED
Conditions: Postoperative Ileus
Interventions: DRUG: Methylnaltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Compare Two Ways of Completing Pain and Sleep Questions and to Evaluate a New Daily Questionaire for Assessing Fatigue in Fibromyalgia Patients
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Interactive Voice Response System (IVRS)|OTHER: Personal Digital Assisstant (PDA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Study of M2ES With Paclitaxel/Carboplatin (TC Regimen) in Advanced Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: M2ES
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Status: COMPLETED
Conditions: Blepharoptosis
Interventions: PROCEDURE: Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine|PROCEDURE: Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: the Relationship of the Use of Eye Masks and Outcomes of Patients With Sepsis in Intensive Care Unit
Status: UNKNOWN
Conditions: Sepsis|Sleep Deprivation|Immune Suppression
Interventions: OTHER: eye masks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Intravitreal Bevacizumab and Triamcinolone With Placebo
Status: UNKNOWN
Conditions: Acute Nonarteritic Anterior Ischemic Optic Neuropathy
Interventions: DRUG: Avastin and Triamcinolone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Safety And Tolerability Of ILV-094 In Subjects With Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: ILV-094
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VATS Evacuation Compared to Reinsertion of Thoracostomy Tube in Persistent Traumatic Haemothorax
Status: UNKNOWN
Conditions: Hemothorax; Traumatic
Interventions: DEVICE: VATS evacuation|DEVICE: thoracostomy tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Tear Film-Based Proteins Associated With Care Solution Induced Corneal Staining
Status: COMPLETED
Conditions: Corneal Staining
Interventions: DEVICE: Opti-Free RepleniSH|DEVICE: ReNu MultiPlus|DEVICE: Balafilcon A|OTHER: Unisol 4
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Oral 6-bromotryptophan on Safety, Pharmacokinetics and Efficacy in Metabolic Syndrome Individuals
Status: RECRUITING
Conditions: Metabolic Syndrome|Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: 6-BT|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Intelligent Rehabilitation Robot Training System Combined With Repetitive Facilitative Exercise on Upper Limb Motor Function After Stroke: a Randomized Control Trial.
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DEVICE: intelligent rehabilitation robot training system|OTHER: repetitive facilitative exercise|OTHER: conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Flexible Fibreoptic Scope With Pentax AWS Videolaryngoscope for Ease of Intubation During Awake Intubation
Status: COMPLETED
Conditions: Anesthesia Intubation Complication
Interventions: DEVICE: Flexible fibreoptic scope|DEVICE: Pentax AWS videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of the Methacholine PC20 Between the Trudell Aeroeclipse* II Ban Nebulizer and the Wright Nebulizer
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Methacholine Chloride|DEVICE: Trudell AeroEclipse*II BAN nebulizer|DEVICE: The English-Wright nebulizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Stage vs. Two Stage Gubernaculum Sparing Laparoscopic Orchidopexy (GSLO)
Status: RECRUITING
Conditions: Cryptorchidism
Interventions: PROCEDURE: Two-Stage GSLO Technique|PROCEDURE: One-Stage GSLO Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Medication Adherence|Liver Transplantation|Kidney Transplantation
Interventions: OTHER: mHealth intervention|OTHER: standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Dorsal Column Stimulation to Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome
Status: TERMINATED
Conditions: Complex Regional Pain Syndrome
Interventions: DEVICE: The Nuvectra Algovita Dorsal Column Spinal Cord Stimulator|DEVICE: The Axium Neurostimulator System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prevention of Left Ventricular Dysfunction During Chemotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Precursor-cell Lymphoblastic Leukemia-Lymphoma|Lymphoid Neoplasm|Multiple Myeloma|Lymphoma|Autologous Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Enalapril and carvedilol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating The Safety and Tolerability of HTC-867 in Healthy Japanese Subjects
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: HTC-867
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock
Status: TERMINATED
Conditions: Sepsis|Sepsis, Severe|Septic Shock
Interventions: OTHER: Sepsis care bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Advagraf vs Prograf in Kidney Transplantation Patients 1 Month After the Transplantation
Status: COMPLETED
Conditions: de Novo Kidney Transplantation
Interventions: DRUG: Advagraf|DRUG: Prograf|DRUG: Corticosteroid|DRUG: Mycophenolate mofetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Of Pain And Quality Of Life Outcomes In Subjects With a Single Painful Venous Leg Ulcer Treated With Apligraf®
Status: UNKNOWN
Conditions: Venous Leg Ulcers
Interventions: DEVICE: Apligraf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: nusinersen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiologic and Clinical Outcomes of Augmentation in Fragility Intertrochanteric Hip Fracture Treatment
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: PROCEDURE: open reduction and internal fixation|DEVICE: TFNA|DEVICE: Augmentation (Cement)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ashwagandha Pharmacokinetics Study in Older Adults
Status: RECRUITING
Conditions: Healthy|Aging
Interventions: DIETARY_SUPPLEMENT: Shoden 240 mg|DIETARY_SUPPLEMENT: Shoden 480 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Safety and Immunogenicity of Omicron COVID-19 Vaccine (Vero Cell), Inactivated in Population 18 Years Old of Age and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Omicron COVID-19 Vaccine (Vero Cell), Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DRUG: ISIS apoC-III Rx|DRUG: ISIS apoC-III Rx|DRUG: ISIS apoC-III Rx|DRUG: Placebo|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrin Sealant for the Sealing of Dura Sutures
Status: COMPLETED
Conditions: Pathological Processes in the Posterior Fossa|Dura Defects
Interventions: BIOLOGICAL: Fibrin Sealant, Vapor Heated, Solvent/Detergent-treated with 500 IU/mL thrombin and synthetic aprotinin (FS VH S/D 500 s-apr)|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Guidance for Proper Treatment of Unexplained Resistant Hyperprolactinemia.
Status: COMPLETED
Conditions: Health Education
Interventions: DRUG: cabergoline 1.5-2 mg/week).orally daily for 1 month plus health education|DRUG: cabergoline 1.5-2 mg/week).orally daily for 1 month without health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PLH for Teens - Hybrid Delivery
Status: COMPLETED
Conditions: Child Maltreatment|Positive Parenting
Interventions: BEHAVIORAL: PLH Teens Original: In-person PLH programme for parents and teens by community-based workers|BEHAVIORAL: PLH Teens Hybrid: Hybrid delivery for parents and teens by facilitators
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability of Typhoid Conjugate Vaccine (EuTCV) in Healthy Adults
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: EuTCV|BIOLOGICAL: Typbar-TCV™|BIOLOGICAL: Typhim Vi®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Botanical Supplement Treatment for Hair Loss
Status: NOT_YET_RECRUITING
Conditions: Androgenetic Alopecia|Female Pattern Baldness|Male Pattern Baldness
Interventions: DIETARY_SUPPLEMENT: Daniel Alain Botanical Supplement Treatment for Hair Loss|DRUG: Topical minoxidil 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CST1 Predictive Model of Oral Glucocorticoid Therapy Sensitivity for Chronic Rhinosinusitis With Polyps
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Glucocorticoids
Interventions: DRUG: Oral Glucocorticoids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclin B1 Peptide-Pulsed Autologous Dendritic Cell Vaccine for Resectable Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Cyclin B1 Peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of NAC in Asthma
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: n-acetylcystine|DRUG: 0.9% saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MyNewOptions: An Online Study of Reproductive Life Planning and Contraceptive Action Planning
Status: COMPLETED
Conditions: Contraceptive Use|Unintended Pregnancy
Interventions: BEHAVIORAL: Reproductive Life Planning (RLP)|BEHAVIORAL: Contraceptive Action Planning|BEHAVIORAL: Contraception information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15)
Status: ACTIVE_NOT_RECRUITING
Conditions: Lyme Disease
Interventions: BIOLOGICAL: VLA15|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) Patients
Status: UNKNOWN
Conditions: Proteinuria
Interventions: DRUG: Dextromethorphan|DRUG: Silymarin|DRUG: sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resynchronization in Paced Heart Failure Patients With Implantable Cardioverter Defibrillator (ICD) Indication
Status: UNKNOWN
Conditions: Heart Failure|Left Bundle-Branch Block
Interventions: PROCEDURE: second LV lead in CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Repetitive Transcranial Magnetic Stimulation in Adult Attention Deficit Disorder
Status: COMPLETED
Conditions: Attention Deficit Disorder|ADHD
Interventions: DEVICE: repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial
Status: COMPLETED
Conditions: Osteoporotic Fractures
Interventions: DRUG: Teriparatide Prefilled Syringe|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Painted Intensity Modulated Radiotherapy Pancreas (DP-IMRT Pancreas)
Status: RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: RADIATION: Dose-Painted Intensity Modulated Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare the Pharmacokinetics of DP-R208
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DP-R208|DRUG: Candesartan cilexetil|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avenir® Cemented Hip Stem - PMCF
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Osteoarthritis|Post-Traumatic Osteoarthritis of Hip|Femoral Neck Fractures|Femoral Head Necrosis|Sequelae From Previous Hip Surgery|Osteotomies|Congenital Hip Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stereotactic Aspiration and Thrombolysis of Intracerebral Hemorrhage: a Prospective Controlled Study
Status: UNKNOWN
Conditions: Hypertensive Intracerebral Hemorrhage
Interventions: DEVICE: YL-1 type of intracranial hematoma puncture needle|DRUG: dehydrating agent, haemostatic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
Status: RECRUITING
Conditions: Solid Tumors
Interventions: DRUG: Rimiducid|DRUG: TROP2-CAR-NK Cells|DRUG: Fludarabine phosphate|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis|Posterior Spinal Fusion
Interventions: PROCEDURE: Posterior Spinal Fusion|DEVICE: Ultrasonic Bone Scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P. Falciparum Infection Dynamics and Transmission to Inform Elimination (INDIE-1a)
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: Enhanced Community Case Management (CCM)|OTHER: Monthly Screening and Treatment (MSAT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-invasive Stroke Volume-based ﬂuid Management in Elderly Patients Undergoing Hip Fracture Surgery Under Spinal Anaesthesia
Status: UNKNOWN
Conditions: Fluid Management|Haemodynamic Instability
Interventions: OTHER: GDFM|OTHER: USUAL CARE - CONTROL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study With AZD5305 and Itraconazole in Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies
Interventions: DRUG: AZD5305|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of AG10 in Subjects With Transthyretin Amyloid Polyneurophathy
Status: WITHDRAWN
Conditions: Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Interventions: DRUG: AG10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures
Status: ENROLLING_BY_INVITATION
Conditions: Procedural Anxiety|Procedural Pain
Interventions: OTHER: VR-PAT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Study of Adenovirus/PSA Vaccine in Men With Hormone - Refractory Prostate Cancer
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer
Interventions: BIOLOGICAL: ADENOVIRUS/PSA VACCINE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bilateral Dispensing Clinical Trial of Stenfilcon A Against Etafilcon A for Astigmatism
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: stenfilcon A toric lens|DEVICE: etafilcon A toric lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation in Schistosomiasis and Soil Transmitted Helminths Control Programmes in Zambia
Status: COMPLETED
Conditions: Schistosomiasis|Helminthiases|Anaemia
Interventions: DRUG: ferrous sulphate (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACPs Combined With CABG in Patients With CHF
Status: UNKNOWN
Conditions: Congestive Heart Failure
Interventions: PROCEDURE: Angiogenic Cell Precursors(ACPs) or Vescell TM|BIOLOGICAL: Angiogenic Cell Precusors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Strategy for Preoperative Chemotherapy in Locally Advanced Gastric/Gastroesophageal Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: S-1|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bone Augmentation Using Particulated Biomaterial and Autogenous Bone, Stabilized by Collagen Membrane and Pins (PaMP)
Status: UNKNOWN
Conditions: Alveolar Bone Grafting|Bone Augmentation
Interventions: PROCEDURE: Biopsy|RADIATION: Computerized Tomography|OTHER: Standardized periapical radiographs|OTHER: Intraoral scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Iguratimod in the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Iguratimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of HLX11 vs. EU-Perjeta® in the Neoadjuvant Therapy of HER2-Positive and HR-Negative Early-stage or Locally Advanced Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Neoplasms|HER2-positive Breast Cancer
Interventions: DRUG: HLX11|DRUG: EU-Perjeta®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interest of an Adapted Physical Activity (APA) Program Among Patients With Juvenile Idiopathic Arthritis: a Feasibility and Efficacy Preliminary Study
Status: RECRUITING
Conditions: Juvenile Idiopathic Arthritis
Interventions: OTHER: Adaptated Physical Activity (APA) + pedometer watch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rectal Temperature Measurement in Detecting Hypothermia During Hip Arthroscopy
Status: COMPLETED
Conditions: Hip Arthropathy|Hypothermia|Orthopedic Disorder
Interventions: PROCEDURE: Rectal temperature measurement|PROCEDURE: Temporal temperature measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Local Tolerability and Safety of Povidone K25 Eye Drops (Artificial Tears Containing Povidone) Versus Placebo in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Povidone K25 eye drops (povidone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia
Status: COMPLETED
Conditions: B-Cell Prolymphocytic Leukemia|Chronic Lymphocytic Leukemia|Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|T-Cell Prolymphocytic Leukemia
Interventions: DRUG: Cyclosporine|DRUG: Fludarabine Phosphate|PROCEDURE: Hematopoietic Cell Transplantation|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|PROCEDURE: Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rigid Annuloplasty Ring With a Band in the Correction of Secondary Tricuspid Insufficiency
Status: COMPLETED
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: band implantation|DEVICE: rigid ring implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Handheld Acne Heat Device
Status: WITHDRAWN
Conditions: Acne Vulgaris
Interventions: DEVICE: Split face: handheld acne heat based device (Zeno Hot Spot) and no treatment|DEVICE: Split face: handheld acne heat based device, Zeno Hot Spot, and topical benzoyl peroxide 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bony M - Stereotactic Ablative Radiotherapy (SABR) of Bony Metastases in Patients With Oligometastatic Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Oligometastatic Disease|Bone Metastases|Stereotactic Body Radiotherapy
Interventions: RADIATION: SABR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Gene Therapy in Treating Lower Leg Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: BIOLOGICAL: VM202 2mg|BIOLOGICAL: VM202 4mg|BIOLOGICAL: VM202 8mg|BIOLOGICAL: VM202 16mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Probiotic Capsules in Promoting Fat Excretion by Human Trial
Status: RECRUITING
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Usefulness of Self-expandable Metal Stents(SEMS) for Malignant Gastric Outlet Obstruction: a Prospective Study Using New Designed Stents
Status: UNKNOWN
Conditions: Malignant Gastric Outlet Obstruction
Interventions: DEVICE: Winged stent (partially covered)|DEVICE: Winged stent (uncovered)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of LAG525 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: LAG525|DRUG: PDR001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study of Glycopyrronium Bromide in Patients With Moderate or Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: glycopyrronium bromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of Stereotactic Body Radiotherapy for Metastatic Prostate Cancer
Status: WITHDRAWN
Conditions: Metastatic Prostate Cancer
Interventions: RADIATION: STEREOTACTIC BODY RADIOTHERAPY to the prostate gland
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of IPS-MA- A Modified Early Supported Employment Intervention for Individuals With Mood or Anxiety Disorders
Status: COMPLETED
Conditions: Affective Disorder|Major Depressive Disorder|Bipolar Disorder|Anxiety Disorder
Interventions: BEHAVIORAL: The IPS-MA method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Impact of Enhanced Recovery After Surgery (ERAS) Program on Clinical and Immunological Outcomes for Minimally-invasive Gastrectomy
Status: UNKNOWN
Conditions: Enhanced Recovery After Surgery for Laparoscopic Gastrectomy for Patients With Gastric Cancer
Interventions: OTHER: Enhanced Recovery After Surgery (ERAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oscillatory Activity in Basal Ganglia Circuits During Normal and Pathological Movement
Status: RECRUITING
Conditions: Parkinson Disease|Epilepsy
Interventions: PROCEDURE: High Resolution Electroencephalogram (EEG-HR)|PROCEDURE: Stereo-electro-encephalography (SEEG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Relationship Between Abdominal Circumference: Hip Ratio and Ephedrine Requirement
Status: COMPLETED
Conditions: Hypotension|Anesthesia, Local|Cesarean Section Complications
Interventions: PROCEDURE: Abdominal circumference was measured at the umbilical level in the standing position at the end of a normal expiration.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effectiveness of the Supraclavicular Block Associated With a Pecs Blocks I to Ensure Analgesia When Placing a Pacemaker
Status: COMPLETED
Conditions: Pain|Pacemaker Ddd
Interventions: PROCEDURE: Local anesthesia made by surgeon|PROCEDURE: Regional anesthesia group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: S0413 Lapatinib in Treating Patients With Locally Advanced or Metastatic Stomach Cancer
Status: COMPLETED
Conditions: Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Gastric Cancer|Stage III Gastric Cancer|Stage IV Gastric Cancer
Interventions: DRUG: lapatinib ditosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Anorectal Biofeedback on Encopresis in School Aged Girls After Sexual Assault
Status: COMPLETED
Conditions: Fecal Incontinence
Interventions: DEVICE: Anorectal manometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT