pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Oral Carbohydrate Solution on Anxiety and Comfort in Patients Undergoing Hip Arthroplasty
Status: COMPLETED
Conditions: Hip Arthropathy|Fasting|Patient Comfort
Interventions: DIETARY_SUPPLEMENT: oral carbohydrate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Adefovir|DRUG: Entecavir|DRUG: Placebo|DRUG: peginterferon alfa-2a [Pegasys]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Pilot Study in Healthy Volunteers to Assess the Parameters for the Design of Bioequivalence Studies on Moderately Lipophilic, Moderately to Highly Protein Bound Drugs Using Dermal Open Flow Microperfusion (dOFM)
Status: COMPLETED
Conditions: Dermatology/Skin - Other|Dermal Pharmacokinetic Measurements
Interventions: OTHER: Dermal pharmacokinetic measurement|DRUG: Lidocaine and prilocaine cream|DRUG: Oraqix® gel|DEVICE: dOFM-System|PROCEDURE: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Oral BTA9881 to Treat RSV Infection
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: DRUG: BTA9881|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Puppet Modeling Technique on Children Undergoing Stressful Dental Procedures
Status: COMPLETED
Conditions: Behavioral Guidance in Pediatric Dentistry
Interventions: BEHAVIORAL: Tell Show and Do Guidance|BEHAVIORAL: Puppet Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TRICAV-II Pivotal: TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation.
Status: NOT_YET_RECRUITING
Conditions: Tricuspid Regurgitation|Tricuspid Valve Disease
Interventions: DEVICE: TricValve® Transcatheter Bicaval Valve System|DRUG: Optimal medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transspinal-Transcortical Paired Stimulation for Neuroplasticity and Recovery After SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries|Paraplegia, Spinal|Tetraplegia/Tetraparesis
Interventions: DEVICE: Transspinal-transcortical paired-associative stimiulation combined with robotic gait training|DEVICE: Transcortical-transspinal paired-associative stimiulation combined with robotic gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized Patients
Status: RECRUITING
Conditions: Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction|Prostate Cancer|Radical Prostatectomy
Interventions: DRUG: Tadalafil 5mg|DRUG: BZ371A|DRUG: Oral Placebo|DRUG: Topical Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Yiqi Huoxue Demolition and Recipes on Recovery Stage of Cerebral Infarction
Status: UNKNOWN
Conditions: Cerebral Infarction
Interventions: DRUG: Yiqi huoxue|DRUG: Yiqi group|DRUG: Huoxue group|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 2013/2017 H7N9 Prime-Boost Interval
Status: COMPLETED
Conditions: Avian Influenza|Influenza Immunisation
Interventions: BIOLOGICAL: A/H7N9|DRUG: AS03|BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013|OTHER: Phosphate Buffered Saline (PBS) diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Safety and Activity of TRL1068 in Chronic Rhinosinusitis
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: TRL1068
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulation of Insulin Secretion by the GLP-1 Receptor
Status: COMPLETED
Conditions: Insulin Secretion
Interventions: DRUG: Exendin (9-39)|DRUG: Dexamethasone|OTHER: Hyperglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed AML
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Tamibarotene|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of an Aerosolized, Recombinant Alpha 1-Antitrypsin in Subjects With Alpha 1-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha1-antitrypsin Deficiency
Interventions: DRUG: Aerosolized, Recombinant Alpha 1-Antitrypsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of V-Loc Suture for Mid-face Lifting in Short-flap Rhytidectomy
Status: TERMINATED
Conditions: Use of the Vloc Suture|Elevation of the Mid-face
Interventions: DEVICE: V-Loc Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Response to Infliximab in Pediatric Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis|Protein Metabolism|Energy Expenditure
Interventions: OTHER: Stable amino acid isotopes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Knee Flexion Angle for Graft Fixation During Single-Bundle Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: PROCEDURE: ACLR done at 0 degrees KFA|PROCEDURE: ACLR done at 30 degrees KFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 52 Week Open Label Extension Trial Following the Recurrence Prevention Study R076477-SCH-301 to Evaluate the Safety and Tolerability of Paliperidone ER in Subjects With Schizophrenia.
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Extended Release OROS® Paliperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enavogliflozin Outcome Trial in Functional Tricuspid Regurgitation
Status: RECRUITING
Conditions: Tricuspid Regurgitation|Heart Failure With Preserved Ejection Fraction
Interventions: DRUG: Enavogliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Protein Bars on Weight Management and Osteoarthicular Health
Status: COMPLETED
Conditions: Overweight and Obesity|Articular Disease
Interventions: DIETARY_SUPPLEMENT: Barrita experimental|DIETARY_SUPPLEMENT: Barrita Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact Of Smoking Cessation Treatment Reimbursement On The Quit Rates In Smokers Motivated To Quit
Status: COMPLETED
Conditions: Smoking Cessation|Insurance Coverage
Interventions: OTHER: Full Smoking Cessation Treatment Coverage (100%)|OTHER: No Smoking Cessation Treatment Coverage (0%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cerebral and Peripheral Perfusion Pilot Study
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of LX102-C01 Treatment of Neovascular Age-Related Macular Degeneration (nAMD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: GENETIC: LX102-C01 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: glipizide|DRUG: metformin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy
Status: UNKNOWN
Conditions: Paralytic Ileus
Interventions: DRUG: Oral/enteral TJ-100 solution|DRUG: Oral/enteral placebo solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Premenopausal Endocrine Responsive Chemotherapy Trial
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: chemotherapy|DRUG: exemestane|DRUG: tamoxifen|DRUG: triptorelin|PROCEDURE: oophorectomy|PROCEDURE: ovarian irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Pharmacodynamic Effects of CT327 on Intra-dermal Nerve Growth Factor (NGF) and Evoked Pain Responses, in Healthy Male Volunteers
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: CT327 (or placebo) followed by placebo (or CT327)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Bioequivalence Study of Two Different Formulations of Candesartan Cilexetil After a Single Oral Dose Administration Under Fasting Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Candesartan Cilexetil 32mg|DRUG: Atacand® PROTECT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Open-Label Study To Evaluate the Safety and Efficacy of the Renal Assist Device In Patients With Acute Renal Failure
Status: COMPLETED
Conditions: Acute Renal Failure
Interventions: DEVICE: Renal tubule assist device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advanced Virtual Exercise Environment Device for Use by Persons With Physical Disabilities
Status: COMPLETED
Conditions: Physically Disabled
Interventions: OTHER: AVEED: Arm rotation, video display|OTHER: AVEED: Arm rotation, without video display|OTHER: AVEED: Leg rotation, arm-energy input, video display|OTHER: AVEED: Leg rotation, arm-energy input, without video display
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: 19Gauge Fine Needle Biopsy (FNB) Versus 22Gauge FNB for Endoscopic Ultrasound Guided Liver Biopsy (EUS-LB)
Status: COMPLETED
Conditions: Chronic Liver Disease
Interventions: PROCEDURE: 19G FNB|PROCEDURE: 22G FNB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET)
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: Botulinum toxin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome
Status: RECRUITING
Conditions: Mitochondrial Diseases|Mitochondrial Encephalomyopathy|Mitochondrial Encephalopathy|Mitochondrial DNA Depletion|Mitochondrial Metabolism Disorders
Interventions: COMBINATION_PRODUCT: deoxycytidine and deoxythymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Peer E-mentoring Intervention to Improve Employment
Status: COMPLETED
Conditions: Cerebral Palsy|Spina Bifida|Juvenile Arthritis|Spinal Cord Injury|Muscular Dystrophy|Physical Disability
Interventions: BEHAVIORAL: Empowering youth towards employment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ED50 of Midazolam Oral Solution for Preoperative Hypnosis in Adults : An Up-and-Down Sequential Allocation Trial
Status: NOT_YET_RECRUITING
Conditions: Dose|Midazolam|Preoperative
Interventions: DRUG: Midazolam oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EXOme Rare Cancers in Children (EXOCARE)
Status: RECRUITING
Conditions: Predisposition, Genetic|Cancer Childhood|Development Delay
Interventions: OTHER: Collection of blood sample or saliva|OTHER: Collection of a tumor sample taken before the participation of the patient in study|OTHER: Collection of blood sample if tumor sample is not available
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CYPRESS - CYPHER for Evaluating Sustained Safety
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel & Aspirin, Prasugrel & Aspirin|DRUG: Placebo & Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Low Metabolic Rate Following Bariatric Surgery
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: DRUG: Ephedrine sulfate with caffeine|DRUG: cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uracil and Tegafur/Leucovorin (UFT/LV) Versus UFT/LV+ Polysaccharide-K (PSK) for Stage IIIa/IIIb Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: UFT, Calcium Folinate, PSK|DRUG: UFT, Calcium Folinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Hospital-manufactured CD19 CAR-T in Children and Adolescents With Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: SNUH-CD19-CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of COR-1 in Heart Failure
Status: COMPLETED
Conditions: Cardiomyopathy, Dilated
Interventions: DRUG: 0.9 % sodium chloride|DRUG: COR-1|DRUG: Standard therapy for heart failure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wellness & Workforce Solution for Lupus/Lupus Nephritis
Status: NOT_YET_RECRUITING
Conditions: Lupus Nephritis
Interventions: BEHAVIORAL: Micro-learning content|BEHAVIORAL: Health360x app|BEHAVIORAL: Culturally congruent coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intra-Erythrocyte Dexamethasone Sodium Phosphate in Ataxia Telangiectasia Patients
Status: COMPLETED
Conditions: Nervous System Disease|Genetic Syndrome
Interventions: DRUG: EryDex Low dose DSP|DRUG: EryDex High dose DSP|DRUG: Pooled Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers
Status: COMPLETED
Conditions: Encephalitis|Japanese Encephalitis
Interventions: BIOLOGICAL: Japanese encephalitis chimeric virus vaccine (JE-CV)|BIOLOGICAL: Japanese encephalitis live vaccine (SA14-14-2 vaccine) (CD.JEVAX®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Deucravacitinib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Treatment Concentrations of Defactinib or VS-6766 for the Treatment of Patients With Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Recurrent Glioblastoma
Interventions: DRUG: Avutometinib|PROCEDURE: Biospecimen Collection|DRUG: Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BV-AVD-R Treatment Children Hodgkin's Lymphoma
Status: ENROLLING_BY_INVITATION
Conditions: Hodgkin Lymphoma
Interventions: DRUG: Brentuximab vedotin|DRUG: Rituximab|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Type 2 Diabetes and Gestational Diabetes Among Women in Kisantu, Democratic Republic of Congo
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Gestational Diabetes
Interventions: BEHAVIORAL: Educational and motivational strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Repeated TMS at Low Frequencies to Reduce Seizure Occurrence
Status: TERMINATED
Conditions: Epilepsy|Status Epilepticus|Epilepsia Partialis Continua|Epilepsia Partialis Continua, Refractory (Medically)
Interventions: DEVICE: Low frequency repeated TMS (LF-rTMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premature Rupture of Mambrane and Unfavourable Cervix
Status: UNKNOWN
Conditions: Cervix; Insufficient Dilatation in Labor
Interventions: DEVICE: COOK RIPENENIG BALLOON+PITOCN|DRUG: PITOCIN|OTHER: double balloonand oxytocin|OTHER: ballon and oxytocin|PROCEDURE: double balloonand and oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)
Status: COMPLETED
Conditions: Complicated Infection|Bacterial Infections
Interventions: DRUG: Avibactam (AVI)|DRUG: Aztreonam (ATM)|DRUG: combination of Aztreonam - Avibactam (ATM-AVI)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: SBRT With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated SCCHN
Status: COMPLETED
Conditions: Previously-Irradiated|Squamous Cell Carcinoma of the Head and Neck Cancer
Interventions: RADIATION: SBRT|DRUG: Cetuximab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body
Status: COMPLETED
Conditions: Acute Pain
Interventions: DRUG: 100 mg GRT0151Y|DRUG: 125 mg GRT0151Y|DRUG: 150 mg GRT0151Y|DRUG: 225 mg GRT0151Y|DRUG: Matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Effectiveness of the IBV® Valve System for the Treatment of Severe Emphysema
Status: COMPLETED
Conditions: Emphysema|COPD
Interventions: DEVICE: IBV® Valve System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Tadalafil Versus Tamsulosin as a Medical Expulsive Therapy for Lower Ureteric Stones
Status: UNKNOWN
Conditions: Lower Ureteric Stones
Interventions: DRUG: Tadalafil versus tamsulosin as MET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children
Status: COMPLETED
Conditions: Ventilator Associated Pneumonia
Interventions: DRUG: 0.12% Chlorhexidine Digluconate|OTHER: Toothbrushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics and Pharmacodynamics of Different Nicotine Salt Concentration Vape System Pods and Free-base Nicotine
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: OTHER: standardized vaping protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK
Status: UNKNOWN
Conditions: Progressive Supranuclear Palsy (PSP)|Corticobasal Degeneration|Multiple System Atrophy (MSA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-Resistant Prostate Cancer Patients
Interventions: DRUG: Irofulven|COMBINATION_PRODUCT: Prednisolone 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robot-assisted Gait Training in Patients With Multiple Sclerosis: Efficacy and Comparison With Traditional Methods
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DEVICE: Lokomat (Hocoma, Zurich, Switzerland)|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of the Effects of Solifenacin Versus Mirabegron on Autonomic System, Arterial Stiffness and Psychosomatic Distress and Clinical Outcomes
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: DRUG: solifenacin|DRUG: mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients
Status: COMPLETED
Conditions: ARDS|Acute Respiratory Distress Syndrome
Interventions: DEVICE: Ventiltor P/V Loop|DEVICE: Electrical Impedance Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gas Mask and Chronic Obstructive Pulmonary Disease (COPD): New Understanding on the Respiratory Index Impact?
Status: COMPLETED
Conditions: Work of Breathing
Interventions: OTHER: measurement of the work of breathing|DEVICE: Gas Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nonintervention Study on Peritoneal Metastasis of Stage IV Gastric Cancer
Status: UNKNOWN
Conditions: Stage IV Gastric Cancer With Metastasis
Interventions: DRUG: S-1|DRUG: oxaliplatin|DEVICE: Hyperthermic Intraperitoneal|DRUG: Paclitaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HS-20089 Combination Treatment in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: HS-20089|DRUG: Adebrelimab|DRUG: Bevacizumab|DRUG: Cisplatin / carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factorial Design to Assess Quit-line Connections
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Connect Smokers to Treatment 1|BEHAVIORAL: Connect Smokers to Treatment 2|BEHAVIORAL: Connect Smokers to Treatment 3|BEHAVIORAL: Connect Smokers to Treatment 4|BEHAVIORAL: Connect Smokers to Treatment 5|BEHAVIORAL: Connect Smokers to Treatment 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer (ETER701)
Status: UNKNOWN
Conditions: Extensive Small Cell Lung Cancer
Interventions: DRUG: TQB2450|DRUG: Anlotinib|DRUG: Etoposide|DRUG: Carboplatin|DRUG: TQB2450（blank）|DRUG: Anlotinib（blank)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suction Catheter as a Guide for Nasotracheal Intubation Under General Anesthesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Intubation Complication
Interventions: DEVICE: suction catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Real-world Evidence Study of BNT162b2 mRNA Covid-19 Vaccine in Brazil
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Pfizer/BioNTech BNT162b2 mRNA COVID-19 vaccine|DRUG: CoronaVac COVID-19 vaccine|DRUG: ChAdOx1 nCoV-19 Covid-19 Vaccine|DRUG: Ad26.COV2.S COVID-19 Vaccine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Dose Effects of Isomaltulose and Sucrose on Glycaemic and Insulinemic Response
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity|Pre Diabetes
Interventions: OTHER: Glucose Solution 1|OTHER: Glucose Solution 2|OTHER: Glucose Solution 3|OTHER: Sucrose/Isomaltulose 100:0|OTHER: Sucrose/Isomaltulose 0:100|OTHER: Sucrose/Isomaltulose 50:50|OTHER: Sucrose/Isomaltulose 60:40|OTHER: Sucrose/Isomaltulose 70:30|OTHER: Sucrose/Isomaltulose 80:20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Pretreatment for Propionibacterium Acnes on Surgical Site Burden in Shoulder Arthroplasty
Status: COMPLETED
Conditions: Shoulder Arthroplasty
Interventions: DEVICE: Blue Light Phototherapy|DRUG: Benzyl Peroxide|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Performance of a Sustained Vacuum System
Status: UNKNOWN
Conditions: Seroma as Procedural Complication|Hematoma Postoperative
Interventions: DEVICE: SOMAVAC® 100 Sustained Vacuum System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase I Dose Escalation Study of IMMU-114 in Relapsed or Refractory NHL and CLL
Status: TERMINATED
Conditions: Non-hodgkin's Lymphoma|Follicular Lymphoma|Mantle Cell Lymphoma|Marginal Zone Lymphoma|Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: IMMU-114
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media (AR01007)
Status: TERMINATED
Conditions: Acute Otitis Media
Interventions: DRUG: AR01|DRUG: Placebo Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Levocetirizine and Fexofenadine in Reducing Symptoms of Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: levocetirizine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Healthy Volunteers Study to Estimate the Effects of Food on the Bioavailability of Oxycodone and Naltrexone/6- Β -Naltrexol From a Extended Release Formulation of Oxycodone With Sequestered Naltrexone
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ALO-02 (Oxycodone Naltrexone)|DRUG: ALO-02 (Oxycodone Naltrexone)|DRUG: ALO-02 (Oxycodone Naltrexone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Single Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Elderly Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIR 561 CL|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Study of Safety, Pharmacokinetics, Pharmacodynamics of Peglamda (Peginterferon Lamda 1) on Healthy Volunteers and the Preliminary Evaluation of Peglamda and Hepasig (Ribavirin) Treatment's Effects on Chronic Hepatitis C Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Peginterferon lambda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients
Status: COMPLETED
Conditions: Severe Sepsis With Septic Shock
Interventions: DRUG: Interleukin-7|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of rSIFN-co in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Carcinoma, Renal Cell|Melanoma|Carcinoma, Hepatocellular|Colon Cancer
Interventions: DRUG: rSIFN-co
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast Enhanced Intraoperative Ultrasound for Detection and Characterization of Renal Mass Undergoing Open Partial Nephrectomy
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: PROCEDURE: Contrast Enhanced Intraoperative Ultrasound|DRUG: DEFINITY|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multi-Center Study of New Medications to Treat Vaginal Infections
Status: COMPLETED
Conditions: Vaginal Infection
Interventions: DRUG: Terconazole|DRUG: Metronidazole|DRUG: Terconazole/metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Progressive Exercise on Renal Transplant Patients
Status: RECRUITING
Conditions: Renal Transplant|Fatigue|Vital Signs|Progressive Relaxation Exercise|Nursing
Interventions: BEHAVIORAL: Progressive relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy
Status: RECRUITING
Conditions: Head and Neck Cancer|Taste Dysfunction
Interventions: DIETARY_SUPPLEMENT: Miraculin|DIETARY_SUPPLEMENT: Miracle Fruit Placebo Cube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Adherent Invasive E. Coli Eradication in Adult Crohn Disease
Status: TERMINATED
Conditions: Crohn Disease|Adherent-invasive E. Coli
Interventions: DRUG: Ciprofloxacin|DRUG: Rifaximin|DRUG: Ciprofloxacin Placebo|DRUG: Rifaximin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PD-HF: A Trial of Peritoneal Dialysis in Patients With Severe Heart Failure and Chronic Kidney Disease
Status: TERMINATED
Conditions: Heart Failure|Chronic Kidney Disease
Interventions: PROCEDURE: Peritoneal Dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degeneration
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: Regorafenib, ophthalmic oily suspension (BAY73-4506)|PROCEDURE: Sham IVT|DRUG: Ranibizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Status: COMPLETED
Conditions: Female Sexual Arousal Disorder
Interventions: DRUG: Caffeine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Electrical Stimulation of Peripheral Muscles in Heart Failure With Preserved Left Ventricular Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Preserved Left Ventricular Ejection Fraction
Interventions: OTHER: Functional electrical stimulation of peripheral muscles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Weekly Paclitaxel, Carboplatin and Irinotecan to Treat Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: Paclitaxel, Carboplatin and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery.
Status: NOT_YET_RECRUITING
Conditions: Surgical Complication
Interventions: DRUG: Tranexamic Acid 100 MG/ML|DRUG: 0.9%sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Household Use of Multiple Micronutrient-fortified Bouillon on Micronutrient Status Among Women and Children in Two Districts in the Northern Region of Ghana
Status: COMPLETED
Conditions: Vitamin A Deficiency|Iron-deficiency|Folate Deficiency|Vitamin B 12 Deficiency|Zinc Deficiency|Anemia
Interventions: DIETARY_SUPPLEMENT: Multiple micronutrient-fortified bouillon cube|DIETARY_SUPPLEMENT: Control bouillon cube (iodine-only)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Correlation Between SUV on 68Ga-HBED-CC-PSMA and Gleason Score in Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 68Ga-HBED-CC-PSMA (DKFZ-11) PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Psycho-social Support on Mental Health and Hope of Adolescents Affected by Earthquake in Nepal
Status: COMPLETED
Conditions: Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Interventions: BEHAVIORAL: Psychosocial support training for school teachers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of DA-2811 When Added to Ongoing Metformin Monotherapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control
Status: RECRUITING
Conditions: Diabetes Mellitus
Interventions: DRUG: DA-2811|DRUG: Forxiga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' GSK2202083A Vaccine in Healthy Infants at 2, 3 and 4 Months of Age
Status: COMPLETED
Conditions: Tetanus|Diphtheria|Haemophilus Influenzae Type b|Poliomyelitis|Acellular Pertussis|Hepatitis B|Diphtheria-Tetanus-aPertussis-Hepatitis B-Poliomyelitis-Haemophilus Influenzae Type b-Neisseria Meni
Interventions: BIOLOGICAL: GSK2202083A vaccine|BIOLOGICAL: 10-valent pneumococcal vaccine (GSK 1024850A)|BIOLOGICAL: Infanrix hexa™|BIOLOGICAL: Menjugate®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of a Nutritional Supplement on Skin Health in Generally Healthy Adults
Status: COMPLETED
Conditions: Skin Health
Interventions: DIETARY_SUPPLEMENT: Beauty From Within|OTHER: Placebo|OTHER: Facial cleansing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Aim of This Study is to Compare the Efficacy of Perioperative Hypertonic Saline 3% Versus Normal Saline (0.9%) in Decreasing Recurrence Risk in Non-muscle Invasive Bladder Cancer
Status: UNKNOWN
Conditions: TCC
Interventions: DRUG: Hypertonic Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses
Status: UNKNOWN
Conditions: Nasal Cavity Cancer|Paranasal Sinus Cancer|Camrelizumab|Induction Chemotherapy|Intensity Modulated Radiotherapy|Concurrent Chemotherapy
Interventions: DRUG: camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study To Compare The Efficacy And Safety Of 0.3 MG Pegaptanib Sodium To Sham Injections In Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Macular Edema|Diabetic Mellitus|Retinal Disease
Interventions: DRUG: pegaptanib sodium|OTHER: sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ex Vivo-Expanded HER2-Specific T Cells and Cyclophosphamide After Vaccine Therapy in Treating Patients With HER2-Positive Stage IV Breast Cancer
Status: WITHDRAWN
Conditions: HER2-positive Breast Cancer|Male Breast Cancer|Stage IV Breast Cancer
Interventions: BIOLOGICAL: HER-2/neu peptide vaccine|DRUG: cyclophosphamide|BIOLOGICAL: ex vivo-expanded HER2-specific T cells|OTHER: laboratory biomarker analysis|OTHER: flow cytometry|OTHER: immunoenzyme technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Phase III Tablet Formulation of Cabotegravir
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: Cabotegravir 30 mg current formulation|DRUG: Cabotegravir 30 mg micronized new formulation 500 M|DRUG: Cabotegravir 30 mg unmicronized new formulation 500 U|DRUG: Cabotegravir 30 mg micronized new formulation 650 M|DRUG: Cabotegravir 30 mg unmicronized new formulation 650 U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Mixture of Non-racemic and Racemic Enantiomers of Bupivacaine in Cesarean
Status: WITHDRAWN
Conditions: Cesarean Delivery
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: Fruquintinib, Adebrelimab, Oxaliplatin, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindfulness Group-based Intervention for Early Psychosis
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia
Interventions: BEHAVIORAL: Mindfulness Ambassador Council for Early Psychosis (MAC-EP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib and Chemotherapy for Patients With Stage IB-IIIA NSCLC With EGFR Mutations (ECON)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Lung Cancer
Interventions: DRUG: erlotinib|DRUG: Pemetrexed|DRUG: Cisplatin|PROCEDURE: Resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Social Media-based Bundle Care of AECOPD Patients.
Status: NOT_YET_RECRUITING
Conditions: Acute Exacerbation of COPD|Pulmonary Disease, Chronic Obstructive|COPD|Lung Diseases, Obstructive|Readmission Rate|Mobile Medical|Bundle Care|Mobile Telemedicine
Interventions: OTHER: Mobile Medical and bundle management|OTHER: Mobile Medical and standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department
Status: TERMINATED
Conditions: Suicide|Suicide Threat|Depression Severe
Interventions: DRUG: Ketamine Hydrochloride|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Magnetic Field and Laser Therapy in Management of Trigeminal Neuralgia
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: OTHER: Electromagnetic therapy.|OTHER: Low level laser therapy (LLLT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Meta-analysis of Fructose-Containing Sugar Sweetened Beverages (SSBs) and Weight Change
Status: UNKNOWN
Conditions: Overweight|Obesity|Diabetes|Prediabetes|Dysglycemia|Metabolic Syndrome
Interventions: OTHER: Fructose-containing sugar sweetened beverages
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Abdominal Massage and Exercise on Primary Dysmenorrhea in University Students
Status: COMPLETED
Conditions: Primary Dysmenorrhea
Interventions: BEHAVIORAL: The exercise group|BEHAVIORAL: The abdominal massage group|BEHAVIORAL: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Saroglitazar Magnesium in Subjects With Severe Renal Impairment and Normal Renal Function
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: Saroglitazar magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER