pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical Study of DC Plus CIK for Patients With Relapse Acute Leukemia After Allo-HSCT
Status: UNKNOWN
Conditions: Acute Leukemia
Interventions: BIOLOGICAL: Genetically modified DCs plus CIK cells|BIOLOGICAL: Donor leukocyte infusions (DLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone
Status: COMPLETED
Conditions: Nutritional Support|Hepato-Biliary Neoplasm|Postoperative
Interventions: DIETARY_SUPPLEMENT: parenteral nutrition supplements|DIETARY_SUPPLEMENT: enteral nutrition supplements|DIETARY_SUPPLEMENT: mixed nutrition supplements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Somatropin + Leuprorelin vs Somatropin Alone in Pubertal Children With Idiopathic Short Stature
Status: COMPLETED
Conditions: Idiopathic Short Stature (ISS)
Interventions: DRUG: somatropin|DRUG: leuprorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HPV Infection and Cervical Neoplasm in Women With Inflammatory Bowel Disease: a Cross-sectional Study
Status: UNKNOWN
Conditions: HPV-Related Cervical Carcinoma|Inflammatory Bowel Diseases|Cervical Neoplasm
Interventions: OTHER: Thinprep Cytology Test (TCT) and HPV infection types were tested by gynecologist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Locally Advanced Breast Cancer: Individualized Treatment Based On Tumor Molecular Characteristics
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: Radiation Therapy (RT)|DRUG: Capecitabine|DRUG: Trastuzumab|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study
Status: TERMINATED
Conditions: Chronic Pelvic Pain Syndrome|Bladder Pain Syndrome
Interventions: DRUG: doxycycline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Silver Diamine Fluoride/ Potassium Iodide in Indirect Pulp Capping of Young Permanent Molars
Status: COMPLETED
Conditions: Tertiary Dentine|Indirect Pulp Capping
Interventions: DRUG: Silver diamine fluoride/ potassium iodide|DRUG: Silver diamine fluoride|DRUG: Resin modified glass ionomer cement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VentaProst Versus Conventionally-Administered Aerosolized Epoprostenol in Patients Undergoing Cardiac Surgery With CPB
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: COMBINATION_PRODUCT: VentaProst
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypotensive Effects of Conventional Dairy Products: Role of Arterial Stiffness
Status: COMPLETED
Conditions: Prehypertension|Stage-1 Hypertension
Interventions: DIETARY_SUPPLEMENT: Non-fat dairy|DIETARY_SUPPLEMENT: Add 4 servings fruit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Baduanjin Exercise on Meridian Energy, Lung Function and Heart Rate Variability in Patients Undergoing Lung Operative.
Status: UNKNOWN
Conditions: Lung Cancer Non Small Cell
Interventions: OTHER: usual care|BEHAVIORAL: Walk|BEHAVIORAL: Baduanjin|BEHAVIORAL: Baduanjin plus walk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Social-emotional Functioning in Neurological Diseases
Status: COMPLETED
Conditions: Alzheimer Disease|Stroke|Parkinson's Disease|Lewy Body Dementia|Huntington Disease
Interventions: BEHAVIORAL: Computerized tests and Electrophysiological measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Shortened Zidovudine Regimens to Prevent Mother-to-Child Transmission of HIV Type 1
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: ZDV Short (mother)-Short (infant): Comparison of zidovudine durations|DRUG: ZDV Short (mother)-Long (infant): Comparison of zidovudine durations|DRUG: ZDV Long (mother)-Short (infant): Comparison of zidovudine durations|DRUG: ZDV Long (mother)-Long (infant): Comparison of zidovudine durations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Cohort 1 - FP-045 oral solution|DRUG: Cohort 2 - FP-045 oral solution|DRUG: Cohort 3 - FP-045 oral solution|DRUG: Placebo (for FP-045 oral solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OPTIMA FORMA Phase 3
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Condition|Chronic Conditions, Multiple
Interventions: BEHAVIORAL: Person-centred integrated care intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Speech Intelligibility Using Transcranial Alternating Current Stimulation (tACS)
Status: RECRUITING
Conditions: Electric Stimulation Therapy|Transcranial Magnetic Stimulation
Interventions: DEVICE: Transcranial alternating current stimulation (tACS)|DEVICE: Transcranial magnetic stimulation (TMS) induced motor-evoked potentials (MEPs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre-hospital ECMO or Conventional Resuscitation for Refractory Cardiac Arrest
Status: NOT_YET_RECRUITING
Conditions: Out of Hospital Cardiac Arrest
Interventions: OTHER: Pre-Hospital ECPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the Manual Therapy on Infant Colic (MT-IF)
Status: COMPLETED
Conditions: Infant Colic
Interventions: OTHER: VISCERAL MANUAL THERAPY-ADVICES|OTHER: ADVICES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Taif University P. O. Box 11099 Taif 21944 Effectiveness of Dry Needling in Management of Myofacial Trigger Point
Status: NOT_YET_RECRUITING
Conditions: Myofacial Trigger Points
Interventions: OTHER: Dry needling ,|OTHER: usual physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Knee Replacement Surgery
Status: COMPLETED
Conditions: Deep Vein Thrombosis|Pulmonary Embolism
Interventions: DRUG: Enoxaparin|DRUG: Apixaban|DRUG: Enoxaparin-matching placebo|DRUG: Apixaban-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Pharmacokinetics of BIIB 722 CL Drinking Solution and of BIIB 722 CL Filmcoated Tablet in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIB 722 CL solution|DRUG: BIIB 722 CL tablet|DRUG: Placebo solution|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors
Status: UNKNOWN
Conditions: Germ Cell Tumor|Central Nervous System Germ Cell Tumor
Interventions: RADIATION: Proton Beam radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients
Status: UNKNOWN
Conditions: Chronic Granulomatous Disease
Interventions: DRUG: Plerixafor|DRUG: Gcsf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: PLX038 + Tuvusertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Twice Weekly Versus Daily Iron Therapy in Treating Anemia in Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy|Iron Deficiency Anemia
Interventions: DRUG: Ferrous Sulfate Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Cancer
Interventions: DRUG: RC48-ADC|DRUG: Envafolimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Antiviral Activity of Remdesivir (GS-5734™) in Participants With Moderate Coronavirus Disease (COVID-19) Compared to Standard of Care Treatment
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Remdesivir|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: FOLFOX regimen|DRUG: dexamethasone|DRUG: floxuridine|DRUG: fluorouracil|DRUG: leucovorin calcium|DRUG: oxaliplatin|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Assiut Femoral Compression Device Versus Manual Compression in the Achievement of Hemostasis
Status: WITHDRAWN
Conditions: Common Femoral Artery Injury|Other Vascular Adverse Event
Interventions: DEVICE: Assiut Femoral Compression Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Remote Diagnosis and Treatment on 24 Hour Ambulatory Blood Pressure Rhythm of OSA Patients
Status: NOT_YET_RECRUITING
Conditions: Sleep Apnea, Obstructive
Interventions: DEVICE: Automatic continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Application of Remazolam in Gastroenteroscopy
Status: UNKNOWN
Conditions: Gastroenterology
Interventions: DRUG: Remimazolam|DRUG: Remimazolam|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ATAC - Arimidex, Tamoxifen Alone or in Combination
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastozole (Arimidex)|DRUG: Tamoxifen (Nolvadex)|DRUG: Anastozole (Arimidex) placebo|DRUG: Tamoxifen (Nolvadex) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: KOREAN Enhanced RecOvery Strategy for Colorectal Surgery
Status: TERMINATED
Conditions: Goal-oriented Fluid Therapy|Colorectal Surgery
Interventions: OTHER: Combined epidural-general anesthesia (CEGA)|DRUG: Volulyte® (6% HES 130/0.4 in balanced solution)|OTHER: Patient-Controlled Epidural Analgesia (PCEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Contribution of the Cerebellum In Sensory-motor Adaptation Via Gamma Oscillations: the Case of Dystonia
Status: COMPLETED
Conditions: Primary Dystonia
Interventions: OTHER: active cerebellar stimulation|OTHER: sham cerebellar stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Different Recovery Methods on Lactic Acid Removal, Flexibility, Strength, and Endurance
Status: COMPLETED
Conditions: Recovery Methods|Exercise Training
Interventions: OTHER: Active Recovery Group|OTHER: Self-Massage with Foam Roller Group|OTHER: Neuromuscular Electrical Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mime Therapy With and Without Neural Mobilization in Bell's Palsy.
Status: RECRUITING
Conditions: Bell Palsy
Interventions: OTHER: Mime Therapy with Neural Mobilization|OTHER: Mime Therapy with Placebo Mobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Indacaterol Dosed in the Evening in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Indacaterol|DRUG: Salmeterol|DRUG: Placebo to Indacaterol|DRUG: Placebo to Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
Status: UNKNOWN
Conditions: Infective Endocarditis
Interventions: DRUG: dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of RLX030 in Pregnant Women With Pre- Eclampsia
Status: TERMINATED
Conditions: Pre-eclampsia
Interventions: DRUG: Placebo|DRUG: RLX030
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TAX + Cisplatin + 5 F/U vs Cisplatin + 5 F/U in SCCHN
Status: COMPLETED
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System
Status: UNKNOWN
Conditions: Apathy|Frontotemporal Dementia|Parkinson Disease|Depressive Symptoms
Interventions: BEHAVIORAL: ECOCAPTURE|BEHAVIORAL: Cognitive and Behavioral experimental tasks|DIAGNOSTIC_TEST: Neuropsychological assessment|BEHAVIORAL: ICM_APATHY_TASKS|OTHER: MRI|BIOLOGICAL: Neurohormonal mechanisms|DIAGNOSTIC_TEST: Supplementary Neuropsychological Assessment - Parkinson's Disease
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Depression With Mindfulness, Acceptance and Commitment
Status: UNKNOWN
Conditions: Psychotherapy|Depression
Interventions: BEHAVIORAL: Mindfulness, Acceptance and Commitment-Therapy|BEHAVIORAL: Jacobson
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery
Status: RECRUITING
Conditions: Breast Neoplasms|Breast Neoplasm Female|Cancer, Breast|Breast Cancer
Interventions: PROCEDURE: Thoracic paravertebral block multiple (3) injections|PROCEDURE: Thoracic paravertebral block single injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus
Status: UNKNOWN
Conditions: Dry Eye Syndromes|HIV Seropositivity
Interventions: DRUG: cyclosporine and sodium carboximethycellulose|DRUG: sodium carboximethycellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Visualization System in Highly Myopic Cataract Operation
Status: RECRUITING
Conditions: Cataract|High Myopia
Interventions: DEVICE: Alcon-NGENUITY®(NG)-system|PROCEDURE: Standard cataract operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Intolerance in Post-COVID Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-COVID Syndrome
Interventions: PROCEDURE: High-Intensity-Interval-Exercise|PROCEDURE: Moderate-Intensity-Continuous-Exercise|PROCEDURE: Strength training|PROCEDURE: Baseline assessment|PROCEDURE: 1 year follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fermented Dairy Products and The Metabolic Syndrome
Status: COMPLETED
Conditions: Overweight or Obesity|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Regular whole milk|DIETARY_SUPPLEMENT: Yogurt with live bacteria|DIETARY_SUPPLEMENT: Yogurt with inactivated bacteria|DIETARY_SUPPLEMENT: Acidified whole milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of After Visit Instructions on Patient Comprehension
Status: COMPLETED
Conditions: After Visit Instructions|Patient Education|Teach-Back Communication|Patient Comprehension
Interventions: BEHAVIORAL: Standardized After Visit Instructions Only|BEHAVIORAL: Standardized After Visit Instructions & Teach Back
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes
Status: RECRUITING
Conditions: Type1 Diabetes Mellitus
Interventions: DIAGNOSTIC_TEST: Oral glucose tolerance test (OGTT)|DIAGNOSTIC_TEST: Hyperglycemic clamp test|DIAGNOSTIC_TEST: Continuous glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: M-PTCy vs BuCy in Haploidentical HSCT for Acute Leukemia
Status: RECRUITING
Conditions: Acute Leukemia
Interventions: DRUG: mitoxantrone liposome|DRUG: ATG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Tolerability of Coltect as Add-on in Patients With Active Ulcerative Colitis - an Open Label
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Coltect
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Development and Application of "Scar-care" Padding on Management of Hypertrophic Scar
Status: COMPLETED
Conditions: Cicatrix, Hypertrophic|Rehabilitation
Interventions: OTHER: SSCP|OTHER: SPMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bariatric Surgery and Weight Loss on Energy Metabolism and Insulin Sensitivity
Status: COMPLETED
Conditions: Obesity|Protein-energy; Imbalance|Insulin Sensitivity|Gastrointestinal Complication
Interventions: PROCEDURE: Laparoscopic Roux-en-Y gastric bypass|PROCEDURE: Laparoscopic gastric banding|PROCEDURE: Laparoscopic sleeve gastrectomy|BEHAVIORAL: Low Calorie Diet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IMaging Della PLAcca Carotidea
Status: COMPLETED
Conditions: Carotid Artery Plaque|Atherosclerosis|Ischemic Stroke
Interventions: DRUG: Visipaque 320 and SonoVue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Iodine Status of Preschoolers Given Micronutrient Powder for 6 Months
Status: COMPLETED
Conditions: Iodine Deficiency|Iodine Deficiency Disorder|Hypothyroidism
Interventions: DIETARY_SUPPLEMENT: MNP group|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Astragalus for Symptomatic Alleviation in High-grade Lymphoma
Status: NOT_YET_RECRUITING
Conditions: High-grade Lymphoma
Interventions: DIETARY_SUPPLEMENT: Astragalus|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Probiotic Intervention, Bile Acids and Lipid Metabolism Metabolic Profile in Healthy Overweight Subjects.
Status: COMPLETED
Conditions: Probiotic Intervention
Interventions: DIETARY_SUPPLEMENT: Probiotic preparation of three Lactobacillus plantarum strains (CECT 7527, CECT 7528, CECT 7529)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bio-Integrative Versus Metallic Screws for Calcaneus Osteotomies
Status: RECRUITING
Conditions: Flatfoot|Bone Resorption|Cavus Deformity|Osteolysis|Complication
Interventions: PROCEDURE: Calcaneus Osteotomy (Metallic)|PROCEDURE: Calcaneus Osteotomy (Bio-integrative)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Cadonilimab Combined With Chemotherapy in Recurrent / Refractory Pleural Mesothelioma
Status: NOT_YET_RECRUITING
Conditions: Pleural Mesothelioma
Interventions: DRUG: Cadonilimab Combined with chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular-Protective Effects of Herbal Medicine Danshen-Gegen
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: D&G 2g|DRUG: D&G 1g|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia
Status: SUSPENDED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: SY-2101|DRUG: Arsenic Trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Acupuncture on Asymptomatic Hyperuricemia
Status: RECRUITING
Conditions: Asymptomatic Hyperuricemia
Interventions: DEVICE: verum acupuncture|BEHAVIORAL: health education|DEVICE: sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wharton's Jelly-derived Mesenchymal Stem Cells in Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis|Hip Osteoarthritis|Knee Osteoarthritis|Glenohumeral Osteoarthritis
Interventions: BIOLOGICAL: Intraarticular injection of WJMSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Behavioral Activation and Physical Exercise on Depression
Status: UNKNOWN
Conditions: Depression
Interventions: BEHAVIORAL: Physical activity without motivational interviewing|BEHAVIORAL: Physical exercise with motivational interviewing|BEHAVIORAL: Behavioral activation with rationale|BEHAVIORAL: Behavioral activation without rationale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Value of Preoperative Sentinel Lymph Node Mapping by Pelvic MR Lymphangiography and SPECT-CT in Cervical Cancer
Status: WITHDRAWN
Conditions: Cervical Cancer
Interventions: PROCEDURE: SPECT-CT sentinel node mapping|PROCEDURE: Magnetic Resonance Lymphangiography sentinel node mapping|PROCEDURE: Intra-operative sentinel node procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of HydroxyColl Bone Graft Substitute in High Tibial Osteotomy Wedge Grafting.
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: HydroxyColl Bone Graft Substitute|DEVICE: DePuy Synthes TomoFix Medial High Tibial Plate (MHT) fixation (Standard of Care)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD
Status: NOT_YET_RECRUITING
Conditions: Congenital Heart Disease|Executive Dysfunction|Attention Disorder
Interventions: BEHAVIORAL: Kleuter Extra training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Asparaginase Encapsulated in Erythrocytes for Patients With ALL and Hypersensitivity to PEG-asparaginase
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: GRASPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety & Blood Levels of IDL-2965 in Healthy Subjects and Patients With a Special Type of Pulmonary Fibrosis
Status: TERMINATED
Conditions: Healthy Volunteers|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: IDL-2965 Oral Capsule|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Ixazomib, Lenalidomide, Dexamethasone Induction and Extended Consolidation Plus Lenalidomide Maintenance in Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Ixazomib|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Effects of Dual-Task Focused Training in Individuals With Chronic Stroke
Status: NOT_YET_RECRUITING
Conditions: Chronic Stroke|Dual Task|Physiotherapy
Interventions: OTHER: Traditional Neurological Rehabilitation + Dual Task Focused Training|OTHER: Traditional Neurological Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of HB-1 for Panic Disorder
Status: COMPLETED
Conditions: Panic Disorder
Interventions: DRUG: HB-01|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sildenafil Citrate on the Success Rate of Ovulation Induction Using Clomiphene
Status: COMPLETED
Conditions: Anovulatory
Interventions: DRUG: Sildenafil & clomiphene citrate|DRUG: clomiphene only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of a Single Brief Intervention of Mindfulness to Reduce Stress Response in a Social Stress Task Paradigm
Status: RECRUITING
Conditions: Mindfulness|Fibromyalgia|Stress
Interventions: BEHAVIORAL: Mindfulness|BEHAVIORAL: Psycho-education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER
Status: TERMINATED
Conditions: Pulmonary Hypertension
Interventions: DRUG: Bardoxolone methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Bioequivalence of Over-encapsulated Oseltamivir Capsules to Marketed Oseltamivir Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: over-encapsulated oseltamivir|DRUG: oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Psychosocial Treatment Intervention in Persons Newly Diagnosed With Rheumatoid Arthritis or Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Arthritis, Rheumatoid|Coping Skills
Interventions: BEHAVIORAL: Intensive individualized psychosocial treatment|BEHAVIORAL: Minimal treatment arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: BI 10773|DRUG: Metformin|DRUG: BI 10773|DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraumbilical Oxytocin Versus Placental Cord Drainage in the Management of 3rd Stage of Labor
Status: UNKNOWN
Conditions: Postpartum Haemorrhage With Retained Placenta
Interventions: DRUG: Intraumbilical vein injection oxytocin|PROCEDURE: placental cord drainage|PROCEDURE: Expectant managment of 3rd stage of labour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: HFNC Compared With Facial Mask in Patients With Chest Trauma Patients
Status: RECRUITING
Conditions: Chest Trauma|Hypoxia
Interventions: PROCEDURE: high flow nasal cannula|PROCEDURE: Oxygen mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Microbiota Transplantation for Decolonization of Carbapenem-resistant Enterobacteriaceae
Status: NOT_YET_RECRUITING
Conditions: Carbapenem-Resistant Enterobacteriaceae Infection|Fecal Microbiota Transplantation
Interventions: BIOLOGICAL: Fecal microbiota transplant|BIOLOGICAL: Sham fecal microbiota transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Sorafenib Dose Escalation in Patients With Previously Untreated Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Sorafenib Escalated Dose|DRUG: Sorafenib Standard Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Double-Blinded Clinical Trial Using Apatone®B for Symptomatic Postoperative Total Joint Replacements
Status: COMPLETED
Conditions: Edematous|Synovitis|Foreign Body Reaction|Osteolysis
Interventions: DRUG: Placebo|DRUG: Apatone®B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore the Existence of Horizontal Transmission of the RIX4414 Vaccine Strain Between Twins Within a Family.
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Myalgesin™ to Support Joint Function in Patients With Knee Osteoarthritis
Status: UNKNOWN
Conditions: Osteoarthritis
Interventions: DIETARY_SUPPLEMENT: Myalgesin™ (celery seed extract, Boswellia serrata extract, Phellodendron extract)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Street Fitness in Surgical Patients Undergoing General Anesthesia After Reversal of Neuromuscular Blockade
Status: UNKNOWN
Conditions: Anesthesia Recovery Period
Interventions: DRUG: Sugammadex|DRUG: Neostigmine/Glycopyrrolate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Anastomosis Sleeve Jejunal (SAS-J) Bypass
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Single Anastomosis Sleeve Jejunal (SAS-J) Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six Week, Randomized, Double-Blind Placebo-Controlled, Suvorexant Augmentation Study of Antidepressant Treatment of Major Depressive Disorder With Residual Insomnia
Status: UNKNOWN
Conditions: Depression|Major Depressive Disorder|MDD|Insomnia
Interventions: DRUG: suvorexant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Trial of Chinese Herbal Medicine SaiLuoTong Capsule
Status: UNKNOWN
Conditions: Vascular Dementia
Interventions: DRUG: high dose group of SaiLuoTong capsule|DRUG: low dose group of SaiLuoTong|DRUG: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Federal Cardiomonitoring System. Determination of the Efficiency of a Single-lead ECG Monitor.
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DEVICE: CardioQvark cardiac monitor and software, single-lead ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intraoperative Lidocaine and Combined With Ketamine on Opioid After Bariatric Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Laparoscopic Bariatric Surgery
Interventions: DRUG: Lidocaine Hydrochloride|DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Delaying the Onset of Nearsightedness Until Treatment Study
Status: WITHDRAWN
Conditions: Myopia
Interventions: DRUG: Atropine Ophthalmic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of XAV-19 for the Treatment of Moderate-to-severe COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: XAV-19|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab Plus Ixabepilone to Treat Patients With Advanced Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Bevacizumab|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Investigate the Effects of Talampanel on the Heart Rhythm
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Talampanel|DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determinants of Tooth Movement in Oral Appliance Treatment of OSA.
Status: RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Mandibular Repositioning Splint|DEVICE: Mandibular Advancement Oral Appliance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Low-Dose Naltrexone in Combination With Standard Treatment in Women With Endometriosis
Status: TERMINATED
Conditions: Endometriosis
Interventions: DRUG: Naltrexone|DRUG: Norethindrone Acetate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Working Memory and Physical Exercise Training in Patients With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Progressive aerobic exercise|BEHAVIORAL: Adaptive cognitive training|BEHAVIORAL: Combined
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Blood Flow Restriction Following ACLR
Status: WITHDRAWN
Conditions: Anterior Cruciate Ligament Injuries|ACL|Physical Therapy
Interventions: OTHER: Blood Flow Restriction Training|OTHER: Sham Blood Flow Restriction Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Maternal Depression and Promoting Infant Social-Emotional Health & Development
Status: COMPLETED
Conditions: Maternal Depression and Parent Practices, Postpartum|Infant Development
Interventions: BEHAVIORAL: Mom & Baby Net|BEHAVIORAL: Depression & Developmental Awareness System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Relay Pro® Thoracic Stent-Graft in Subjects With Traumatic Injury of the Descending Thoracic Aorta
Status: ACTIVE_NOT_RECRUITING
Conditions: Other Specified Injury of Thoracic Aorta
Interventions: DEVICE: Relay Pro Thoracic Stent-Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder|Treatment Resistant Depression
Interventions: DEVICE: Deep Brain Stimulation Model 3387 Model 3389
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lipohypertrophy Monitoring Study
Status: COMPLETED
Conditions: Diabetes Mellitus|Lipohypertrophy|Hypoglycemia
Interventions: BEHAVIORAL: Online education (BdandMe) for injection technique|DEVICE: 4mm needles
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assess the Safety and Immunogenicity of M-001 as A Standalone Influenza Vaccine and as A H5N1 Vaccine Primer in Adults
Status: COMPLETED
Conditions: Influenza|Healthy
Interventions: BIOLOGICAL: Multimeric 001 (M-001)|BIOLOGICAL: H5N1 influenza vaccine|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Project 2: Strategies for Reducing Nicotine Content in Cigarettes
Status: COMPLETED
Conditions: Nicotine Dependence|Tobacco Smoking
Interventions: BEHAVIORAL: Normal Nicotine Control Group|BEHAVIORAL: Immediate Nicotine Reduction Group|BEHAVIORAL: Gradual Nicotine Reduction Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endoscopic Ultrasound Versus Endoscopic Retrograde Cholangiopancreatography (ERCP) Tissue Sampling for the Diagnosis of Suspected Pancreatico-Biliary Cancer
Status: COMPLETED
Conditions: Pancreaticobiliary Cancers|Jaundice|Bile Duct Obstruction
Interventions: PROCEDURE: ERCP|PROCEDURE: EUS FNA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic Myopia
Status: WITHDRAWN
Conditions: Myopic Choroidal Neovascular Membrane
Interventions: DRUG: Intravitreal Pegaptanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etanercept Treating Patient With Acute ST Segment Elevated Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: DRUG: Etanercept|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MALDITOF Versus Routine Clinical Microbiology for Identifying Pathogens; a Randomized Diagnostic Trial
Status: COMPLETED
Conditions: Bacterial Infections|Fungal Infections
Interventions: DEVICE: Malditof|OTHER: Routine clinical microbiology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cardiovascular Effects of Angiotensin (1-7) in Essential Hypertension
Status: TERMINATED
Conditions: Hypertension|Hypertension, Essential
Interventions: DRUG: Angiotensin (1-7)|DRUG: Trimethaphan|DRUG: Phenylephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Lymphedema Prevention Program Based on Theory of Knowledge-attitude-practice on Postoperative Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer Lymphedema
Interventions: BEHAVIORAL: Lymphedema prevention protocols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Relationship Between OND and ONSD Measured by TOS With Clinical, Radiological, and Electrophysiological Parameters in MS Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: OTHER: Transorbital Sonography|OTHER: Orbita Magnetic Resonance Imaging|OTHER: Visual Evoked Potentials|OTHER: Optical Coherence Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MMF and Calcineurin Inhibitor Withdrawal in CAN
Status: TERMINATED
Conditions: Immunosuppressive Agents|Kidney Failure, Chronic|Kidney Transplantation
Interventions: DRUG: mycophenolate mofetil (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of the Administration of MEDI-528 When Administered in Multiple Doses to Adults With Mild Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: MEDI528 0.3 mg/kg|BIOLOGICAL: MEDI528 1 mg/kg|BIOLOGICAL: MEDI528 3 mg/kg|OTHER: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vessel Density in nAMD After Longterm Anti-VEGF Treatment Compared to Recently Started Anti-VEGF Treatment
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DIAGNOSTIC_TEST: Optical Coherence Tomography angiography (OCTA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Prospective Clinical Trial - Obturator Reflex Predictors and Blockage
Status: UNKNOWN
Conditions: Malignant Neoplasm of Urinary Bladder
Interventions: PROCEDURE: obturator nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Severely Obese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Obesity and Diabetes Mellitus, Type 2
Interventions: DRUG: JNJ-64565111 Dose Level 1|DRUG: JNJ-64565111 Dose Level 2|DRUG: JNJ-64565111 Dose Level 3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin and Paclitaxel With or Without Cediranib Maleate in Treating Patients With Metastatic or Recurrent Cervical Cancer That Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: carboplatin|DRUG: cediranib maleate|DRUG: paclitaxel|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT