pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: CTNow: A Clinical Trials Education Program for Rural Cancer Patients and Oncology Providers
Status: NOT_YET_RECRUITING
Conditions: Cancer|Oncology
Interventions: OTHER: Patient Education Intervention|OTHER: Provider Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Risk Factors for Hearing Loss as a Result of Exposure to Noise During Military Training in the IDF
Status: UNKNOWN
Conditions: Hearing Loss, Noise-Induced
Interventions: OTHER: Guidance on auditory protection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Odanacatib When Administered to Adolescents and Young Adults Treated With Glucocorticoids (MK-0822-066)
Status: TERMINATED
Conditions: Osteoporosis
Interventions: DRUG: Odanacatib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance, Pharmacokinetic and Antiviral Study of Amdoxovir in Combination With Zidovudine in Adults With HIV
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: zidovudine|DRUG: amdoxovir|PROCEDURE: pharmacokinetic sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Multicentre Study on Preference and Satisfaction of Canadian Women for the Transdermal Contraceptive Patch vs. Previous Primary Contraceptive Method
Status: COMPLETED
Conditions: Female Contraception
Interventions: DRUG: norelgestromin; ethinyl estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: DCLL9718S|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Female Urethral Catheterization - Instillation of the Lubricating Gel Into the Urethra or Pouring it on the Catheter's Tip?
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: Instillation into the urethra|OTHER: pouring the gel on the catheter's tip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Docetaxel Followed by CEF (Cyclophosphamide, Epirubicin and 5-Fluorouracil) Compared to Docetaxel and Capecitabine Followed by CEX (Cyclophosphamide, Epirubicin and Capecitabine) as Adjuvant Treatment for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Glycopyrronium on Morning Symptoms and Pulmonary Function in Patients With Moderate to Severe COPD
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Glycopyrronium|DRUG: Tiotropium|DRUG: Placebo to glycopyrronium|DRUG: Placebo to tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PEARL Program: Empowerment Program for Patients With Type 2 Diabetes (HK4)
Status: COMPLETED
Conditions: Diabetes
Interventions: BEHAVIORAL: Patient Peer Support and Empowerment|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Linking Data Using Smartphone Application, 'Well Check', on Clinical Outcomes in Patients With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Physician-managed "WellCheck" use|OTHER: self-managed "WellCheck" use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Influence of Intraoperative Analgesia on the Postoperative Morphine Consumption
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Remifentanil|DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Different Cryocompression Devices and Skin Temperature of the Knee
Status: COMPLETED
Conditions: Temperature Change, Body
Interventions: DEVICE: Physiolab S1|DEVICE: Breg Vpulse|DEVICE: Aircast Cryo/Cuff|DEVICE: GameReady|DEVICE: Physiolab Gel Therapy Wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electroacupuncture and Pelvic Floor Muscle Training for Male Stress Urinary Incontinence
Status: RECRUITING
Conditions: Stress Urinary Incontinence
Interventions: BEHAVIORAL: Pelvic floor muscle training|OTHER: Electroacupuncture|OTHER: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, International, Multicenter, Observational Study to Evaluate the Clinical Performance and Safety of a Silicone-coated Transparent Postoperative Dressing
Status: TERMINATED
Conditions: Wounds and Injuries|Skin Diseases
Interventions: DEVICE: Leukomed T / Tplus skin sensitive treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Clinical and Biomechanical Research of the New Arthroscopic Technique for the Treatment of High-grade Dislocation of the Acromioclavicular Joint
Status: UNKNOWN
Conditions: Dislocation of the Acromioclavicular Joint
Interventions: PROCEDURE: Arthroscopic-Assisted Acromioclavicular Joint Reconstruction Using the TightRope Device|PROCEDURE: Traditional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fruit Consumption on Risk Factors of Chronic Disease
Status: COMPLETED
Conditions: Vascular Stiffness
Interventions: DIETARY_SUPPLEMENT: macro- and micro-nutrient matched control (240 ml)|DIETARY_SUPPLEMENT: Orange juice|DIETARY_SUPPLEMENT: whole orange fruit|DIETARY_SUPPLEMENT: Processed whole orange
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Billroth II Versus Roux-en-Y for the Gastrojejunostomy in the Pancreatoduodenectomy
Status: COMPLETED
Conditions: Pancreatoduodenectomy
Interventions: PROCEDURE: Roux-en-Y for the gastrojejunostomy reconstruction|PROCEDURE: Billroth II for the gastrojejunostomy reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effect of Trimetazidine During the Primary PCI on Cardiac Function in Patients With ST-elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DRUG: Trimetazidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Application of Simethicone in Esophagogastroscopy
Status: COMPLETED
Conditions: Gastric Disease
Interventions: OTHER: Simethicone administration 20-30 min before the procedure|OTHER: Simethicone administration 31-60 min before the procedure|OTHER: Simethicone administration > 60 min before the procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Extracorporeal Shock Wave Therapy Applied to the Plantar Region in Individuals With Hemiplegia
Status: COMPLETED
Conditions: Extracorporeal Shock Wave Therapy|Kinaesthesia|Sensory Disorders
Interventions: DEVICE: ESWT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
Status: UNKNOWN
Conditions: Pulmonary Malformation
Interventions: DEVICE: 3D printed model|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Celecoxib, Paclitaxel, and Carboplatin in Treating Patients With Cancer of the Esophagus
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: carboplatin|DRUG: celecoxib|DRUG: paclitaxel|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Babies Through Infant Centered Feeding
Status: COMPLETED
Conditions: Overweight|Obesity|Infant Overnutrition|Feeding Behavior|Feeding Patterns
Interventions: BEHAVIORAL: Healthy Babies|BEHAVIORAL: Expanded Food and Nutrition Education Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Multiple Doses of LY2922470 in Participants With Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: LY2922470
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Aerobic Exercise for Concussion
Status: COMPLETED
Conditions: Mild Traumatic Brain Injury|Acute Brain Injury|Brain Concussion
Interventions: OTHER: Aerobic Exercise|OTHER: Stretching Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Analgesic Efficacy of Dexketoprofen Trometamol, Meperidine, and Paracetamol in Renal Colic
Status: COMPLETED
Conditions: Analgesia|Renal Colic
Interventions: DRUG: Dexketoprofen Trometamol|DRUG: Meperidine Injectable Solution|DRUG: Paracetamol|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial
Status: COMPLETED
Conditions: Menopause|Dyslipidemias|Homocystinaemia
Interventions: DRUG: Tenavit®|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Nafamostat and Unfractionated Heparin in RRT for Sepsis Associated AKI
Status: NOT_YET_RECRUITING
Conditions: Sepsis
Interventions: DRUG: Nafamostat Mesylate|DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery
Status: COMPLETED
Conditions: Thrombosis|Hip Replacement
Interventions: DRUG: DU176b - action is the prevention of venous thromboembolism by the use of a Factor Xa inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Stretching Techniques of Knee Muscles and Their Effect on Joint Range, Suppleness and Muscle Activity in Elderly
Status: COMPLETED
Conditions: Muscle Tightness|Muscle Weakness
Interventions: OTHER: Proprioceptive Neuromuscular Stretching - Contract Relax stretching (PNF-CR)|OTHER: Static Stretching (SS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase II Trial to Assess FOLFIRI+Aflibercept Efficacy in Patients With Oxaliplatin-pretreated Metastatic Colorectal Cancer With or Without ACE Polymorphisms
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI+aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ComPAS Low-WAZ RCT Mali
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Malnutrition in Infancy|Acute Malnutrition in Childhood|Underweight
Interventions: DIETARY_SUPPLEMENT: Simplified dose of ready-to-use therapeutic food (RUTF)|DIETARY_SUPPLEMENT: Standard dose of ready-to-use therapeutic food (RUTF)|DIETARY_SUPPLEMENT: No nutritional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sacituzumab govitEcan in THYroid Cancers
Status: NOT_YET_RECRUITING
Conditions: Differentiated Thyroid Cancer|Anaplastic Thyroid Cancer
Interventions: DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: Chitosan-N-acetylcysteine eye drops (concentration of 0.1%)|OTHER: Physiological saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study on Rotavirus Vaccine to Evaluate Lot-to-lot Consistency and Interference With Routine UIP Immunization
Status: COMPLETED
Conditions: Rotavirus Gastroenteritis
Interventions: BIOLOGICAL: BRV-PV Lot A + DPT-HepB-Hib + OPV|BIOLOGICAL: BRV-PV Lot B + DPT-HepB-Hib + OPV|BIOLOGICAL: BRV-PV Lot C + DPT-HepB-Hib + OPV|BIOLOGICAL: ROTARIX + DPT-HepB-Hib + OPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Erector Spina Plane Block and Lumbar Plexus Block in Femoral Fracture Surgery
Status: COMPLETED
Conditions: Femur Fracture|Erector Spinae|Lumbar Plexus|Ultrasound Guide
Interventions: PROCEDURE: ESP block|PROCEDURE: LP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of the Dual MDM2/MDMX Inhibitor ALRN-6924 in Pediatric Cancer
Status: COMPLETED
Conditions: Leukemia|Brain Tumor|Solid Tumor|Lymphoma
Interventions: DRUG: ALRN-6924|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Synchronous Video (Telemedicine) Consulation in the Prehospital Setting
Status: COMPLETED
Conditions: Emergencies|Prehospital|Telemedicine|Telehealth
Interventions: DEVICE: Video Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia B|Hemophilia A
Interventions: DRUG: Standard of Care FIX Replacement therapy|DRUG: Standard of Care FVIII Replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: ABTECT-2 - ABX464 Treatment Evaluation for Ulcerative Colitis Therapy -2
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: ABX464|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S9805, High-Dose Melphalan Plus Peripheral Stem Cell Transplantation Followed by Interferon Alfa in Treating Patients With Waldenstrom's Macroglobulinemia
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant interferon alfa|DRUG: dexamethasone|DRUG: melphalan|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation
Status: RECRUITING
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|DRUG: Enasidenib|DRUG: Enasidenib Mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin II Receptor Blockers (ARB) and ACE Inhibitors (ACEI) on Silent Brain Infarction and Cognitive Decline
Status: COMPLETED
Conditions: Brain Infarction|Hypertension
Interventions: DRUG: Angiotensin II Receptor Antagonists|DRUG: Angiotensin-converting Enzyme Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Acute Effects of Blueberries on Cognition and Mood in the Postpartum
Status: NOT_YET_RECRUITING
Conditions: Mood|Parents|Healthy
Interventions: DIETARY_SUPPLEMENT: Blueberry drink|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Risk Factors and Biomarkers for Adaptation and Resilience to Spaceflight
Status: ACTIVE_NOT_RECRUITING
Conditions: Resilience|Mood|Performance|Stress, Psychological
Interventions: BEHAVIORAL: 8-Days in an Isolation, Confinement Unit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of JNJ-38518168 in Symptomatic Adult Participants With Uncontrolled, Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: JNJ-38518168
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bronchodilator Effect of a Single Dose of Fluticasone Furoate (FF)/ Vilanterol (VI) 100/25 Micrograms (mcg) Combination When Administered in Adult Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF/VI 100/25 mcg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cabiralizumab Given With Nivolumab With and Without Chemotherapy in Patients With Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Advanced Pancreatic Cancer
Interventions: BIOLOGICAL: Cabiralizumab|DRUG: Nab-paclitaxel|DRUG: Onivyde|BIOLOGICAL: Nivolumab|DRUG: Fluorouracil|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Leucovorin|DRUG: Irinotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Pilot Study on Budesonide/Formoterol
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Budesonide|DRUG: Formoterol|DEVICE: Easyhaler|DEVICE: Turbohaler Forte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Study Comparing Skin Adhesive With Staple for Surgical Incision Closure After Laparoscopic / Robotic Bowel Resection
Status: UNKNOWN
Conditions: Benign or Malignant Diseases With Indication for Laparoscopic or Robotic Colorectal Resection
Interventions: PROCEDURE: LSA (liquid skin adhesive)|PROCEDURE: stapler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia|Diabetes|Smoking|Cardiovascular Risk Factor|Cardiovascular Diseases
Interventions: OTHER: Prioritized Clinical Decision Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Immunogenicity of Preservative Free Inactivated Split Influenza Vaccine, Using the Strain Composition 2006/2007 in Non-Elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: preservative free inactivated split influenza vaccine using the strain composition 2006/2007
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Developing Adaptive Treatment Strategies for Children and Adolescents With Obsessive-compulsive Disorder.
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: fluoxetine|BEHAVIORAL: Group cognitive-behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TELAMON P™ Implant/INFUSE® Bone Graft/CD HORIZON® Spinal System Pilot Study
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: TELAMON P™ /INFUSE® Bone Graft/CD HORIZON® Spinal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Shiga Progression of Diabetes, Nephropathy and Retinopathy
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Pioglitazone add on to SU or biguanide|DRUG: SU or Biguanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First-line Treatment With Dacomitinib Plus Anlotinib for Patients With Advanced NSCLC With EGFR 21L858R Mutations
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: Dacomitinib+Anlotinib|DRUG: Dacomitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Absorption to the Blood After Administration of Single and Multiple Doses of AZD8154 in Healthy Participants.
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD8154
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Elderly Patients With Medical Conditions
Status: COMPLETED
Conditions: Aging|Constipation|Multi-Core Disease
Interventions: DIETARY_SUPPLEMENT: microbial cell preparation [MCP]|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Cartoon Watching and Bubble Blowing as Distraction Methods During Venipuncture on Pain, Anxiety, and Fear in Children Aged 6-8 Years
Status: COMPLETED
Conditions: Pain|Anxiety|Fear|Child, Only
Interventions: BEHAVIORAL: Bubble Blowing|BEHAVIORAL: Cartoon Watching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Adult Acute Lymphoblastic Leukemia in Remission|Adult Acute Myeloid Leukemia in Remission|CD45-Positive Neoplastic Cells Present|Chronic Myelomonocytic Leukemia|Previously Treated Myelodysplastic Syndrome|Refractory Anemia With Excess Blasts|Refractory Anemia With Ring Sideroblasts|Refractory Cytopenia With Multilineage Dysplasia|Refractory Cytopenia With Multilineage Dysplasia and Ring Sideroblasts
Interventions: PROCEDURE: Allogeneic Bone Marrow Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|RADIATION: Iodine I 131 Monoclonal Antibody BC8|OTHER: Laboratory Biomarker Analysis|DRUG: Mycophenolate Mofetil|DRUG: Tacrolimus|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Respiratory Alterations of Acid-base Equilibrium: Acute and Chronic Renal Response
Status: UNKNOWN
Conditions: Acute Respiratory Variations of Acid-base Equilibrium
Interventions: OTHER: Increase minute ventilation|OTHER: Decrease minute ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy Combination With Local Radiotherapy and rhGM-CSF for Oligometastatic Stage IV NSCLC Patients
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: BIOLOGICAL: rhGM-CSF|DRUG: Pemetrexed|RADIATION: Local Radiotherapy|DRUG: Single agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous vs. Intermittent Infusion Vancomycin
Status: RECRUITING
Conditions: Vancomycin
Interventions: DRUG: Vancomycin Continuous Infusion|DRUG: Vancomycin Intermittent Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics
Status: RECRUITING
Conditions: Anesthesia|Emergence Delirium|Anesthesia Awareness|Behavior Child Problems|Postoperative Delirium|Postoperative Complications
Interventions: PROCEDURE: MAC adjustment to PSI between 25 and 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Probiotics in Prevention of Allergies, Obesity and Caries
Status: COMPLETED
Conditions: Eczema|Allergy|Asthma|Obesity|Dental Caries
Interventions: DIETARY_SUPPLEMENT: Lactobacillus F19|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating a Group-based Therapeutic Yoga Program for Burnout
Status: WITHDRAWN
Conditions: Anxiety|Insomnia|Burnout, Professional|Depression|Loneliness
Interventions: BEHAVIORAL: A primary care group-based therapeutic yoga program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Growing Up: Intervening With HIV-Positive Adolescents in Resource-Poor Settings
Status: COMPLETED
Conditions: HIV Infection
Interventions: BEHAVIORAL: N'ap Grandi|BEHAVIORAL: N'ap Grandi - A|BEHAVIORAL: Health Promotion - A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MYPLAN - Effectiveness of a Safety Plan App to Manage Crisis of Persons at Risk of Suicide
Status: COMPLETED
Conditions: Suicide Prevention|Suicidal Thoughts|Suicide Attempts
Interventions: OTHER: MYPLAN-safety plan as an application for smart phones|OTHER: safety plan on paper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Verapamil in Acute Paroxysmal Supra Ventricular Tachycardia(PSVT) Recurrence Control
Status: COMPLETED
Conditions: Paroxysmal Supraventricular Tachycardia
Interventions: DRUG: Verapamil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: One-Step Universal Adhesives: A 3-year Clinical Trial in Class II Composite Restorations
Status: RECRUITING
Conditions: Dental Caries Class II|Marginal Integrity of Composite Restorations With Universal Adhesives
Interventions: OTHER: One-step universal adhesive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vayarin® Medical Food Study for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder (ADHD)
Interventions: OTHER: Vayarin®|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and Efficacy Trial of Oral Testosterone Undecanoate (TU) in Hypogonadal Men
Status: COMPLETED
Conditions: Male Hypogonadism
Interventions: DRUG: Oral testosterone undecanoate|DRUG: topical testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Hepatitis B Surface Antigen (HB s Ag) Enough Alone as a Screening Test Before Immunosuppressive Therapies?
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: OTHER: HBV core antibodies testing. • Real time PCR testing.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety of and Immune Response to an Investigational HIV-1 Vaccine With or Without Interleukin-12 (IL-12) in HIV-1 Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Profectus HIV MAG pDNA vaccine|BIOLOGICAL: IL-12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients
Status: RECRUITING
Conditions: Hypovolemia|Hemorrhage|Fluid Responsiveness
Interventions: OTHER: Mostcare® device|OTHER: Transthoracic cardiac ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surgical Sperm Retrieval in Non-obstructive Azoospermic Men: mTESE vs. TESA
Status: COMPLETED
Conditions: Non-obstructive Azoospermia
Interventions: PROCEDURE: mTESE|PROCEDURE: TESA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Olmesartan on Cerebral Glucose Metabolism, Vascular Inflammation and Adipose Tissue
Status: UNKNOWN
Conditions: Efficacy of Olmesartan on Cerebral Glucose Metabolism in Essential Hypertension
Interventions: DRUG: Olmesartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
Status: COMPLETED
Conditions: Epilepsy|Tuberous Sclerosis Complex
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Z0063|DRUG: Gaviscon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy Study of TAK-700 in Patients With Nonmetastatic Castration-resistant Prostate Cancer and a Rising Prostate-specific Antigen
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: TAK-700
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cisplatin-based Chemotherapy Combined With P16_37-63 Peptide Vaccination in Patients With HPV-positive Cancers
Status: COMPLETED
Conditions: HPV-induced Cancers
Interventions: BIOLOGICAL: P16_37-63 peptide combined with Montanide® ISA-51 VG|BIOLOGICAL: P16_37-63 peptide without Montanide® ISA-51 VG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Effective Recovery From Labor Urinary Incontinence (PERL)
Status: COMPLETED
Conditions: Urinary Incontinence|Pelvic Organ Prolapse|Perinatal Laceration|Second Stage Labor
Interventions: BEHAVIORAL: Videotape, routine care, PME instruction|BEHAVIORAL: PME practice and record keeping (in diaries)|BEHAVIORAL: Non-directed or directed,spontaneous or sustained pushing|PROCEDURE: Data collection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Monitoring of Abdominal Soft Tissue
Status: TERMINATED
Conditions: Pancreatic Cancer|Liver Cancer
Interventions: DEVICE: Ultrasound scan of the pancreas|DEVICE: Ultrasound scan of the Liver|DRUG: Reference ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study of Velaglucerase Alfa in Children and Adolescents With Type 3 Gaucher Disease
Status: COMPLETED
Conditions: Gaucher Disease, Type 3
Interventions: BIOLOGICAL: velaglucerase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Hyaluronic Acid-Based Vaginal Moisturizer Medical Device to Ease Symptoms of Vaginal Dryness
Status: COMPLETED
Conditions: Vaginal Disease
Interventions: DEVICE: Hidrante HA|DEVICE: Cumlaude Hidrante Interno®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Factors and Quality of Life in the Effect of Fear of COVID-19 With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BEHAVIORAL: Survey Form, The Hospital Anxiety and Depression Scale, The Fear of COVID-19 Scale,World Health Organization Quality of Life Scale- Bref Form
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sleep Modulation to Treat Depression
Status: RECRUITING
Conditions: Major Depressive Disorder|Healthy
Interventions: DEVICE: Auditory closed-loop stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Expanded/Activated Gamma Delta T-cell Infusion Following Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: EAGD T-cell infusion (Phase I)|DRUG: EAGD T-cell infusion (Expansion)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Bihemispheric Transcranial Direct Current Stimulation on Motor Function in Stroke Patients
Status: COMPLETED
Conditions: Stroke|Upper Extremity Paresis|Transcranial Direct Current Stimulation
Interventions: DEVICE: tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Plus CapeOX as First-Line Treatment for Advanced GC/GEJC With High TMEscore
Status: NOT_YET_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Cadonilimab plus CapeOX chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ranibizumab Treatment for Retinal Vein Occlusion
Status: UNKNOWN
Conditions: Macular Edema Due to BRVO/CRVO
Interventions: DRUG: Ranibizumab, 0.5mg, Intravitreal
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Status: RECRUITING
Conditions: Hypertensive Emergency-associated Hemolytic Uremic Syndrome
Interventions: DRUG: Soliris®|DRUG: Renin angiotensin system blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HVPG-Guided Therapy Versus EVL Plus NSBB in Second Prophylaxis of Esophageal Variceal Bleeding
Status: UNKNOWN
Conditions: Esophageal Varices in Cirrhosis of the Liver
Interventions: PROCEDURE: HVPG-guided therapy|PROCEDURE: Routing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures
Status: COMPLETED
Conditions: Wound Heal
Interventions: PROCEDURE: closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesive|PROCEDURE: closure of wound using braided silk suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACE393-103 Vaccination Challenge Study
Status: UNKNOWN
Conditions: Campylobacter Infection
Interventions: BIOLOGICAL: ACE393|BIOLOGICAL: Placebo vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Compare Efficacy/Safety of Repeat Doses of Ferumoxytol With Iron Sucrose in CKD Subjects With IDA and on Hemodialysis
Status: COMPLETED
Conditions: Iron Deficiency Anemia Treatment|Chronic Kidney Disease(CKD)
Interventions: DRUG: Ferumoxytol|DRUG: Iron Sucrose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Pulsatility Index Compared To Mean Arterial Blood Pressure Guided Protocol In Sepsis Induced Encephalopathy:
Status: COMPLETED
Conditions: Sepsis|Norepinephrine|Encephalopathy
Interventions: OTHER: Transcranial doppler pulsatility index guided protocol|OTHER: Mean arterial blood pressure guided protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Angioplasty for Acute Myocardial Infarction in Patients With Symptom Duration Above 12 Hours
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: PROCEDURE: Primary angioplasty with stent and abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Efficacy of AGR Tablet as a Treatment of Perennial Allergic Rhinitis in Korean
Status: COMPLETED
Conditions: Allergic Rhinitis|Perennial Allergic Rhinitis|Non-seasonal Allergic Rhinitis
Interventions: DRUG: AGR tablet|DRUG: Placebo (for AGR tablet and/or Active Comparator)|DRUG: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm
Status: COMPLETED
Conditions: Pain|Premature Infant|Human Milk|Breastfeeding
Interventions: OTHER: expressed breast milk|BEHAVIORAL: sucrose 24% oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Mesylate Imatinib Capsule in Chronic Myeloid Leukemia Body
Status: COMPLETED
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: mesylate imatinib capsule|DRUG: Glivec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Squalamine Lactate Eye Drops in Combination With Ranibizumab in Patients With Diabetic Macular Edema (DME)
Status: WITHDRAWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Squalamine Lactate Ophthalmic Solution 0.2%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chloroquine With Taxane Chemotherapy for Advanced or Metastatic Breast Cancer After Anthracycline Failure (CAT)
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Docetaxel|DRUG: Abraxane|DRUG: Ixabepilone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RM-718 in Healthy Subjects and in Patients With HO
Status: RECRUITING
Conditions: Hypothalamic Obesity
Interventions: DRUG: Part A: RM-718 or placebo (matched to specific RM-718 dose cohort)|DRUG: Part B: RM-718 or placebo (matched to specific RM-718 dose cohort)|DRUG: Part C: RM-718
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Open-label Extension Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD)
Status: ENROLLING_BY_INVITATION
Conditions: FSHD|FSHD1|FSHD2|FMD|FMD2|Fascioscapulohumeral Muscular Dystrophy|Fascioscapulohumeral Muscular Dystrophy Type 1|Fascioscapulohumeral Muscular Dystrophy Type 2|Dystrophies, Facioscapulohumeral Muscular|Dystrophy, Facioscapulohumeral Muscular|Facioscapulohumeral Muscular Dystrophy 1|Facioscapulohumeral Muscular Dystrophy 2|Facio-Scapulo-Humeral Dystrophy|Atrophy, Facioscapulohumeral|Atrophies, Facioscapulohumeral|Facioscapulohumeral Atrophy|Muscular Dystrophies|Muscular Dystrophy, Facioscapulohumeral|FSH Muscular Dystrophy|Landouzy Dejerine Dystrophy|Landouzy-Dejerine Muscular Dystrophy|Dystrophies, Landouzy-Dejerine|Dystrophy, Landouzy-Dejerine|Landouzy-Dejerine Syndrome|Muscular Dystrophy, Landouzy Dejerine|Progressive Muscular Dystrophy|FSH
Interventions: DRUG: AOC 1020
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Supplement Containing Fucoidan on Basal Body Temperature
Status: COMPLETED
Conditions: Low Basal Body Temperature
Interventions: DIETARY_SUPPLEMENT: Supplement containing fucoidan, EPA, and DHA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single-dose Pharmacokinetics and Relative Bioavailability of Two Different Formulations of Opicapone
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BIA 9-1067 non-micronized|DRUG: BIA 9-1067 micronized
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Gestational Diabetes|Hypoglycemia, Neonatal
Interventions: DRUG: Insulin, Aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MASTER Study (MAmmary Cancer STatin ER Positive Study)
Status: RECRUITING
Conditions: Breast Cancer Female|Estrogen Receptor Positive Tumor
Interventions: DRUG: Atorvastatin 80 Mg Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Parenteral and Enteral Nutrition on Skeletal Muscle Genomics
Status: COMPLETED
Conditions: Muscle Loss
Interventions: DIETARY_SUPPLEMENT: Parenteral nutrition (PN)|DIETARY_SUPPLEMENT: Enteral nutrition|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Incidence and Duration of Unintentional Neuromodulation Effects After Pulmonary Vein Isolation in Patients With Atrial Fibrillation.
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: ablation- pulmonary vain isolation- crioablation|PROCEDURE: ablation- pulmonary vain isolation- pulsed field ablation (PFA)|PROCEDURE: ablation- pulmonary vain isolation- radiofrequency ablation (RF)|PROCEDURE: Electrophysiological study (EPS)|DIAGNOSTIC_TEST: Holter EKG|OTHER: Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p