pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy and Safety of Intraparenchymal Portal Vein Covered Stents in Treating Portal Hypertension and Its Complications
Status: NOT_YET_RECRUITING
Conditions: Portal Hypertension
Interventions: DEVICE: The intraparenchymal portal vein covered stent|DEVICE: TIPS Covered Stent System GORE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Two Silicone Hydrogel Contact Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lens A (comfilcon A lens)|DEVICE: Lens B (lehfilcon A lens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Two Tramadol Contramid® OAD 300 mg Controlled-Release Tablets From Two Different Manufacturing Sites Following a 300 mg Dose in Healthy Subjects Under Fasting and Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tramadol hydrochloride|DRUG: Tramadol HCl|DRUG: Tramadol HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Vincristine in induction|DRUG: Daunorubicin in induction|DRUG: Prednisone in induction|DRUG: Metotrexato in induction|DRUG: Cytarabine in induction|DRUG: Hydrocortisone in induction|DRUG: Idarubicin in induction-2|DRUG: Fludarabine in induction-2|DRUG: Ara-C in induction-2|DRUG: G-CSF in induction-2|DRUG: Dexamethasone in consolidation-1|DRUG: Vincristrine in consolidation-1|DRUG: Metotrexato in consolidation-1|DRUG: PEG-ASP in consolidation-1|DRUG: Dexamethasone in consolidation-2|DRUG: ARA-C in consolidation-2|DRUG: PEG-ASP in consolidation-2|DRUG: Dexamethasone in consolidation-3|DRUG: Vincristine in consolidation-3|DRUG: Metotrexato in consolidation-3|DRUG: PEG-ASP in consolidation-3|PROCEDURE: allogeneic HSCT|PROCEDURE: Allo HSCT with reduced-intensity conditioning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study Evaluating the Effect of Vitamin D on Clinical Outcome in Autistic Children
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Vitamin D3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Preemptive Paracetamol and Ibuprofen on Headache and Myalgia in Patients After Electroconvulsive Therapy
Status: COMPLETED
Conditions: Postoperative Pain|Myalgia|Headache
Interventions: DRUG: placebo|DRUG: paracetamol|DRUG: ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Estimate The Effect Of Repeat-Dose Rifampin On The Pharmacokinetics Of CP-690,550 In Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tasocitinib (CP-690,550) plus Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Radiation Toxicity
Interventions: DRUG: Amifostine trihydrate|DRUG: Cisplatin|RADIATION: Intracavitary brachytherapy|RADIATION: External beam radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Hip Instructional Prehabilitation Program for Enhanced Recovery (HIPPER)
Status: COMPLETED
Conditions: Hip Osteoarthritis
Interventions: OTHER: HIPPER|OTHER: OASIS Online Educational Webinars
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions
Status: RECRUITING
Conditions: Chronic Pelvic Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Tone|DIAGNOSTIC_TEST: Tenderness|DIAGNOSTIC_TEST: Contraction|DIAGNOSTIC_TEST: Relaxation|DIAGNOSTIC_TEST: Electromyography|DIAGNOSTIC_TEST: Transperineal|DIAGNOSTIC_TEST: Pressure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)
Status: NOT_YET_RECRUITING
Conditions: ART Adherence
Interventions: BEHAVIORAL: POC urine assay informed enhanced ART adherence counselling for viral suppression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Effectiveness of Different High-intensity Interval Training Programs in Cardiac Rehabilitation
Status: RECRUITING
Conditions: Cardiac Rehabilitation
Interventions: OTHER: Progressive High Intensity Interval Training (PRO-HIIT)|OTHER: Constant High Intensity Interval Training (CON-HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Buspirone for Functional Dysphagia
Status: COMPLETED
Conditions: Functional Dysphagia|Ineffective Esophageal Motility
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Sodium nitroprusside|DRUG: Glucose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Fatigability in Individuals With Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DIETARY_SUPPLEMENT: Nitrate-rich beetroot juice|DIETARY_SUPPLEMENT: Beetroot juice with nitrate extracted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study Evaluating the Use of HLX10 in Combination With HLX04 for the Treatment of Advanced Hepatocellular Carcinoma (HCC) Patients
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: HLX10 3mg/kg|DRUG: HLX04 5mg/kg|DRUG: HLX04 10mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Association Between Tretinoin and Clindamycin on the Treatment of Acne Mild and Moderate
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: application of the topic gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Smartphone-based Personalized Intervention on Cognitive and Cerebrovascular Health in CIRCLE-CHINA
Status: COMPLETED
Conditions: Cognitive Impairment|Stroke|Dementia
Interventions: BEHAVIORAL: Self-monitoring and personalized feedback on smartphone app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sedation and Nursing Management in EEG Recording in Children
Status: COMPLETED
Conditions: Electroencephalography|Melatonin|Chloral Hydrate|Hydroxyzine|Sleep Deprivation
Interventions: OTHER: Sedation and Nursing Management in EEG Recording in Children|DRUG: Chloral Hydrate|DRUG: Hydroxyzine|DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 68Ga-BNU-PSMA PET/CT in Patients With Various Types of Cancer
Status: UNKNOWN
Conditions: Tumor|Positron-Emission Tomography|Metastasis
Interventions: DIAGNOSTIC_TEST: 68Ga-BNU-PSMA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy
Status: COMPLETED
Conditions: Cystoscopy
Interventions: DRUG: furosemide|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Playing With a Toy Nebulizer and Watching Cartoons on the Fear and Anxiety on Children
Status: NOT_YET_RECRUITING
Conditions: Fear|Anxiety|Inhalant Use
Interventions: OTHER: Playing with toy nebulizer|OTHER: Cartoon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02)
Status: SUSPENDED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Low-dose freeze-dried recombinant tuberculosis vaccine (AEC / BC02)|BIOLOGICAL: High-dose freeze-dried recombinant tuberculosis vaccine (AEC / BC02)|BIOLOGICAL: High-dose adjuvant for freeze-dried recombinant tuberculosis vaccine (AEC / BC02)|BIOLOGICAL: Lyophilized recombinant tuberculosis vaccine (AEC / BC02) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of LymphoStat-B™ (Monoclonal Anti-BLyS Antibody) in Subjects With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Placebo|DRUG: Belimumab 1 mg/kg|DRUG: Belimumab 4 mg/kg|DRUG: Belimumab 10 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oligo-metastases NPC Patients Received Radiation for Primary Tumors and Treatments for Metastatic Lesions
Status: RECRUITING
Conditions: Nasopharyngeal Cancer|Neoplasm Metastasis
Interventions: RADIATION: radical radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Three Psychoeducational Group Interventions for Veterans With Tinnitus
Status: COMPLETED
Conditions: Tinnitus
Interventions: BEHAVIORAL: Coping Effectiveness Training|BEHAVIORAL: Cognitive-behavioral therapy|BEHAVIORAL: Acceptance and Commitment Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function
Status: UNKNOWN
Conditions: COPD|Emphysema|Small Airway Disease
Interventions: DRUG: Tiotropium + formoterol/beclometasone|DRUG: tiotropium + placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Hericium Erinaceus on Clinical Patients With Hearing Impairment
Status: UNKNOWN
Conditions: Tinnitus
Interventions: DIETARY_SUPPLEMENT: Hericium honey bolus|DIETARY_SUPPLEMENT: Placebo honey bolus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daily Activities Are Sufficient to Induce Dynamic Pulmonary Hyperinflation and Dyspnea in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Dynamic Lung Hyperinflation|COPD Patients|Activities of Daily Livin.
Interventions: OTHER: Hyperinflation and ADL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate Safety and Exploratory Efficacy of KTP-001 in Subjects With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: DRUG: KTP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Health Education and Yoga on Menopause Symptoms and Quality of Life According to Pender's Model
Status: NOT_YET_RECRUITING
Conditions: Quality of Life|Health Education|Yoga|Menopause Symptoms
Interventions: BEHAVIORAL: health education and yoga intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure
Status: COMPLETED
Conditions: Modified Release Oral Formulation|Left Ventricular Systolic Dysfunction|Chronic Heart Failure|History of Chronic Heart Failure|Left Ventricular Ejection Fraction|Pharmacokinetics|Echocardiogram
Interventions: DRUG: Omecamtiv Mecarbil Matrix F1 Formulation|DRUG: Omecamtiv Mecarbil Matrix F2 Formulation|DRUG: Placebo|DRUG: Omecamtiv Mecarbil Swellable Core Technology F2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fast-Release Orodispersible Tramadol Tablet (Tradonal Odis®) as Analgesia for Hysterosalpingography
Status: COMPLETED
Conditions: Infertility|Pain
Interventions: DRUG: Fast-release Orodispersible Tramadol Tablet (Tradonal odis®)|PROCEDURE: Hysterosalpingography (HSG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biodistribution and Kinetics of 18F-AraG in Non-Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: 18F-AraG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Salmeterol-Fluticasone Combined Inhaled Therapy for Non-cystic Fibrosis Bronchiectasis
Status: COMPLETED
Conditions: Bronchiectasis
Interventions: DRUG: ICS+LABA|OTHER: routine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INTegrated Assessment of intERmediate Coronary Stenoses by Fractional Flow rEserve (FFR) and Near-infraREd Spectroscopy (NIRS)
Status: UNKNOWN
Conditions: Borderline Coronary Stenoses Assessment, Fractional Flow Reserve, Plaque Composition
Interventions: DEVICE: FFR and IVUS-NIRS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Botanical Blend on the Gut Microbiome and Gut-Skin-Axis in Small Intestinal Bacterial Overgrowth (SIBO)
Status: UNKNOWN
Conditions: Small Intestinal Bacterial Overgrowth (SIBO)
Interventions: DIETARY_SUPPLEMENT: Liquid Tincture|DIETARY_SUPPLEMENT: GI Detox|DIETARY_SUPPLEMENT: Olivirex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Initial Evaluation of a Stepped Care Model for Treating Mild to Moderate Childhood Anxiety in Primary Care
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety Disorder
Interventions: BEHAVIORAL: Step-by-Step|BEHAVIORAL: Cool Kids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Coexistence of Cerebral and Coronary Atherosclerosis in Acute Ischemic Cerebrovascular Disease Patients Registry
Status: RECRUITING
Conditions: Coexistence of Cerebral and Coronary Atherosclerosis|Acute Ischemic Cerebrovascular Disease
Interventions: OTHER: observational only- no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Status: RECRUITING
Conditions: PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Interventions: GENETIC: RP-A601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Window of Opportunity Trial of Durvalumab (MEDI4736) to Identify Immune Dynamics in Operable Non-small Cell Lung Cancer (NSCLC) (MIRACLE)
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Minimal Stimulation or Clomiphene Citrate in Treatment of Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: clomiphene citrate +highly purified uFSH|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Selenium as Augmentation Treatment for Sertraline Resistant Major Depression
Status: SUSPENDED
Conditions: Major Depression
Interventions: DIETARY_SUPPLEMENT: selenium supplementation|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Apatinib as 3rd/4th Line Treatment in Patients With Advanced Non-Squamous Non-small Cell Lung Cancer Harboring Wild-type Epidermal Growth Factor Receptor (EGFR)
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Apatinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Microbial Community Transplantation on the Armpit/Foot
Status: COMPLETED
Conditions: Heavy, Bad Body Odour From Armpit|Heavy, Bad Body Odour From Foot
Interventions: BIOLOGICAL: Microbial transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping and Physiotherapeutic Exercises for Children With DCD
Status: UNKNOWN
Conditions: Developmental Coordination Disorder
Interventions: BEHAVIORAL: Kinesio Taping - Functional Movement Power Training|BEHAVIORAL: Jogging with placebo taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EnVision CF Multicenter Study of Glucose Tolerance in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis-related Diabetes
Interventions: DIAGNOSTIC_TEST: Oral glucose tolerance test|DIAGNOSTIC_TEST: Continuous glucose monitoring|DIAGNOSTIC_TEST: Dexa scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Differential Lung Ventilation vs. CPAP
Status: COMPLETED
Conditions: One Lung Ventilation|Continuous Positive Airway Pressure|Differential Lung Ventilation
Interventions: DEVICE: cpap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined PRF of the Pudendal Nerve With Ganglion Impar Block Effectively Alleviates Pudendal Neuralgia
Status: RECRUITING
Conditions: Pudendal Neuralgia|Pulsed Radiofrequency
Interventions: PROCEDURE: Combined pulsed radiofrequency of the pudendal nerve with ganglion impar block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Erectile Dysfunction - Long Term Safety and Efficacy
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: Udenafil 50 mg|DRUG: Udenafil 100 mg|DRUG: Udenafil 150 mg|DRUG: Placebo Matching 50 mg Udenafil|DRUG: Placebo Matching 100 mg Udenafil|DRUG: Placebo Matching 150 mg Udenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Oxytocin on the Neurobiology of Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: BIOLOGICAL: Intranasal oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Axitinib in Patients With Recurred or Metastatic Adenoid Cystic Carcinoma
Status: COMPLETED
Conditions: Recurrent ACC, metastaticACC, Unreaectable ACC
Interventions: DRUG: Axitinib|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in ACS Patients
Status: WITHDRAWN
Conditions: Acute Coronary Syndrome|Renal Insufficiency|Ischemia, Myocardial
Interventions: PROCEDURE: Remote Ischemic Preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Registry Study to Compare the Cardiopulmonary Exercise Test Parameters Before and After Cardiac Rehabilitation in Patients With Chronic Total Occlusion of the Coronary Arteries
Status: COMPLETED
Conditions: Coronary Artery Disease|Total Occlusion of Coronary Artery
Interventions: BEHAVIORAL: cardiac rehabilitation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study DiaDEP
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Type1diabetes
Interventions: DRUG: Iohexol renal clearance measurement|DEVICE: microcirculation assessment through Laser Doppler associated to iontophoresis.|DEVICE: Cardiovascular assessment though Intima-media Thickness and Extra-media Thickness measurement|BIOLOGICAL: Blood sampling|BIOLOGICAL: Urine sampling|DEVICE: High-resolution peripheral quantitative computed tomography (HR-pQCT)|RADIATION: Dual-energy X-ray (DXA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Fluoxetine in Major Depressive Disorder (MDD) Short-Term Dosing
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Fluoxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Long-term Efficacy and Safety of Human-cl rhFVIII in Previously Treated Patients (PTPs)
Status: COMPLETED
Conditions: Severe Hemophilia A
Interventions: BIOLOGICAL: Human-cl rhFVIII
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical 2% Povidone-Iodine Gel in Verruca Vulgaris
Status: UNKNOWN
Conditions: Warts
Interventions: DRUG: VBP-245|DRUG: Placebo Gel (no Povidone-Iodine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of Oxcarbazepine Monotherapy in Children With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial Seizures
Interventions: DRUG: Oxcarbazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Study of Different Local Anesthetic Mixtures
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: 1% Lidocaine with Epinephrine (1:100,000)|DRUG: 0.25% Bupivacaine with Epinephrine (1:200,000)|DRUG: 0.5% Lidocaine, 0.125 Bupivacaine, and epi (1:150,000)|DRUG: 1% Lidocaine, 0.5% Bupivacaine, and epinephrine (1:150,000)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Safety and Efficacy of CAR-T Cells in the Treatment of R/R Neuromyelitis Optica
Status: RECRUITING
Conditions: Neuromyelitis Optica
Interventions: DRUG: CD19 CAR-T cells injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomised Investigation of the Safety and Efficacy of Micardis® vs Ramipril Using ABPM
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Mild to Moderate Atopic Dermatitis
Interventions: DEVICE: Zarzenda|DRUG: Elidel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone Maintain Mitochondrial Quality of Cumulus Cells in Poor Ovarian Responders
Status: COMPLETED
Conditions: Poor Responders|Dehydroepiandrosterone
Interventions: DIETARY_SUPPLEMENT: dehydroepiandrosterone (DHEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Disorder
Interventions: DRUG: Lamotrigine|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Gait Training for People With Knee Osteoarthritis Using Dual Belt Treadmill
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Replacement
Interventions: BEHAVIORAL: Gait training program|BEHAVIORAL: Conventional training only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Y Transconjunctival Approach in Open Reduction of Zygomatic Maxillary Complex Fracture
Status: COMPLETED
Conditions: Zygomatic Fractures
Interventions: PROCEDURE: Y modification of transconjunctival approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Trial of BAT5906 Injection in Patients With Wet Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-related Macular Degeneration
Interventions: DRUG: BAT5906 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study of Increased Preterm Arginine INTake (PAINT18)
Status: RECRUITING
Conditions: Preterm|Nutritional Deficiency|Immune System and Related Disorders
Interventions: DIETARY_SUPPLEMENT: Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Pediatric Recurrent Progressive Low-grade Gliomas|Pediatric Progressive Low-grade Gliomas
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and the Efficacy of IV Fosnetupitant/Palonosetron (260 mg/0.25 mg) Combination Compared to Oral Netupitant/Palonosetron (300 mg/0.5 mg) Combination for the Prevention of CINV in AC Chemotherapy in Women With Breast Cancer
Status: COMPLETED
Conditions: Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: fosnetupitant/ palonosetron|DRUG: netupitant/palonosetron|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Flexitouch Lymphedema System in Treating Stage II Lymphedema in Patients With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|Lymphedema
Interventions: OTHER: questionnaire administration|OTHER: lymphedema management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Influence of Seat Height on Hemiplegic-pattern Propulsion of Manual Wheelchairs
Status: COMPLETED
Conditions: Wheelchairs|Hemiplegia
Interventions: DEVICE: Neutral seat height|DEVICE: Very low seat height|DEVICE: Low seat height|DEVICE: Very high seat height|DEVICE: High seat height
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2
Status: ACTIVE_NOT_RECRUITING
Conditions: Apnea, Obstructive Sleep|Obesity
Interventions: DEVICE: Bioelectrical Impedance Analysis (BIA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First in Human Study of a Monoclonal Antibody (SOL-116) Targeting BSSL (Bile Salt-Stimulated Lipase), Single and Multiple Dose Parts
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: SOL-116|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of DN Versus TU Along With Routine PT in Patients With for Chronic Neck Pain RCT
Status: RECRUITING
Conditions: Neck Pain
Interventions: DIAGNOSTIC_TEST: Dry needling|DIAGNOSTIC_TEST: Therapeutic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gene Therapy Study in Severe Hemophilia A Patients With Antibodies Against AAV5
Status: ACTIVE_NOT_RECRUITING
Conditions: Hemophilia A|Gene Therapy|Clotting Disorders|Blood Disorder
Interventions: BIOLOGICAL: Valoctocogene Roxaparvovec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Soybean Germ Extract on Decrease of Body Fat
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Soybean Germ Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: SuperTROPO (Better Diagnostics of Myocardial Infarction With a Test for Special Forms of Troponin)
Status: RECRUITING
Conditions: Myocardial Infarction|Myocardial Ischemia
Interventions: DIAGNOSTIC_TEST: SuperTROPO novel assay to measure the long forms of cTnT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Musculoskeletal and Obstetric Management Study
Status: UNKNOWN
Conditions: Lower Back Pain|Pelvic Pain|Musculoskeletal Pain
Interventions: OTHER: Manual Therapy|OTHER: Standard OB Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Foods Together With a Small Dose of Alcohol on Alcohol Levels in Healthy Subjects
Status: COMPLETED
Conditions: Alcohol Use, Unspecified
Interventions: OTHER: SOBAR|OTHER: Control food|OTHER: Full meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Hativ® ELectrocardiogram Monitoring on Patients With Suspected Arrhythmia
Status: RECRUITING
Conditions: Arrhythmia
Interventions: DEVICE: Continous ECG Patch|DEVICE: Intermittent handheld ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Electrical Muscle Stimulation on Waist Circumference in Adults
Status: COMPLETED
Conditions: Abdominal Obesity
Interventions: DEVICE: Electrical Muscle Stimulation|DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of Ultrasound-guided Greater Occipital Nerve Block and Pulsed Radiofrequency Therapy in Chronic Migraine Patients
Status: COMPLETED
Conditions: Chronic Migraine, Headache
Interventions: PROCEDURE: USG Guided Greater Occipital Nerve Block|PROCEDURE: USG Guided Greater Occipital Nerve Block and Pulsed Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Study of a Peptide Vaccine in Patients With Stage III Colon Cancer
Status: COMPLETED
Conditions: Colonic Neoplasms|Colorectal Neoplasms
Interventions: BIOLOGICAL: EP2101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Agent™ and SeQuent® Please Paclitaxel Coated Balloon Catheters in Coronary In-stent Restenosis (AGENT-ISR)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Restenosis|Coronary Atherosclerosis|Coronary Arteriosclerosis
Interventions: DEVICE: Agent Paclitaxel-coated balloon|DEVICE: SeQuent® Please Paclitaxel-coated Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial and Medication Treatment for Anxiety in Alcoholism
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Anxiety Disorders
Interventions: DRUG: Venlafaxine|BEHAVIORAL: CBT|OTHER: Progressive muscle relaxation therapy (PMR)|OTHER: Placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Home Based Monitoring of Kidney Transplants Utilizing Capillary Microsamples
Status: RECRUITING
Conditions: Kidney Transplant Failure and Rejection
Interventions: PROCEDURE: Standard follow-up|PROCEDURE: Home-based monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief
Status: RECRUITING
Conditions: Carpal Tunnel|Dexmedetomidine|Ozone|Dexamethasone
Interventions: DRUG: Dexmedetomidine|DRUG: Ozone|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Sirolimus and Maraviroc on CCR5 Expression and the HIV-1 Reservoir in HIV-infected Kidney Transplant Recipients
Status: WITHDRAWN
Conditions: Hiv|Kidney Transplant|HIV Reservoir|CCR5
Interventions: DRUG: Sirolimus + Maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Upper Extremity Wearable Robotic Orthosis on Improving Upper Extremity Motor Function and Activities of Daily Living in Persons With Spinal Cord Injury
Status: COMPLETED
Conditions: SCI - Spinal Cord Injury
Interventions: DEVICE: MyoMo|OTHER: Myo-SB|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Nutritional Intervention and Respiratory Infections in Older Subjects
Status: UNKNOWN
Conditions: Upper Respiratory Infections|Lower Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: Multivitamins and minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Resuscitation Strategies in Septic Shock
Status: UNKNOWN
Conditions: Septic Shock|Critically Ill
Interventions: DEVICE: Transpulmonary Thermodilution|DEVICE: Surviving Sepsis Guidelines (SSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Intravenous Dexamethasone at Different Times as Adjunvants for Brachial Plexus Blocks
Status: COMPLETED
Conditions: Analgesia|Dexamethasone|Brachial Plexus Block|Intravenous Drug Usage|Time|Shoulder Surgery
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LIDRISE Study: A Phase 3 Study on the Efficacy and Safety of STN1013800 (Oxymetazoline HCl 0.1% Eye Drops, Single Dose) in the Treatment of Acquired Blepharoptosis.
Status: NOT_YET_RECRUITING
Conditions: Acquired Blepharophimosis
Interventions: DRUG: STN1013800 (0.1% Oxymetazoline Hydrochloride) eye drops in single dose containers|OTHER: Placebo (0% Oxymetazoline Hydrochloride) eye drops in single dose containers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A SHR0302 BA Study on Healthy Subjects
Status: ACTIVE_NOT_RECRUITING
Conditions: Autoimmune Diseases
Interventions: DRUG: SHR0302 quick release tablets|DRUG: SHR0302 sustained-release tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Intervention for Minors in Possession of Alcohol/Drugs: A Feasibility Study
Status: COMPLETED
Conditions: Substance Use Disorder|Delinquency
Interventions: OTHER: Motivational Enhancement Therapy /Adol and PW for parents|OTHER: Motivational Enhancement Therapy for adolescents|OTHER: Drug Education for adolescents, Parenting Wisely for parents|OTHER: Drug Education for adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flufenamic Acid for Hospitalised Influenza Infection
Status: UNKNOWN
Conditions: Influenza A
Interventions: DRUG: FFA, clarithromycin, oseltamivir|DRUG: Oseltamivir alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Pegilodecakin|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Itacitinib in Combination With Corticosteroids for the Treatment of Acute GVHD
Status: COMPLETED
Conditions: Graft-versus-host Disease (GVHD)
Interventions: DRUG: Itacitinib (200 mg)|DRUG: Itacitinib (300 mg)|DRUG: prednisone or methylprednisolone (corticosteroids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Pilot Trial of Mecamylamine for Treatment of Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autistic Disorder|Pervasive Developmental Disorder
Interventions: DRUG: mecamylamine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Sitagliptin 100 mg|DRUG: Canagliflozin 300 mg|DRUG: Metformin|DRUG: Sulphonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Meningioma|Neuroblastoma|Medulloblastoma
Interventions: RADIATION: 90Y-DOTA tyr3-Octreotide|DIAGNOSTIC_TEST: 68Ga-DOTATOC PET Positron Emission Tomography (PET) whole body scan|DRUG: Amino Acids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EVALUATION OF THE EFFICACY OF THE HYDROXYCHLOROQUINE-AZITHROMYCIN COMBINATION IN THE IN THE PREVENTION OF COVID-19 RELATED SDRA
Status: WITHDRAWN
Conditions: Sars-CoV-2, Community-Acquired Pneumonia,COVID-19
Interventions: DRUG: Hydroxychloroquine and azithromycin treatment arm.|DRUG: Hydroxychloroquine|DRUG: Control arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A TEst and Treat Intervention aMong Current People Who Inject Drugs With HCV Attending Needle and Syringe PrOgrams
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DEVICE: HCV RNA Point of Care|DRUG: Sofosbuvir/velpatasvir|DRUG: Glecaprevir/pibrentasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effectiveness of the Sexual Health Psychoeducation Program for Physically Disabled Adolescents
Status: COMPLETED
Conditions: Sexual Health|Adolescent|Physically Disabled|Psychological|Education
Interventions: BEHAVIORAL: Sexual Health Psychoeducation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SmART Heart: Study of mHealth Apps to Reduce Cancer-Treatment Effects on the Heart
Status: COMPLETED
Conditions: Acute Leukemia in Remission|Hematopoietic Cell Transplantation Recipient|Lymphoma
Interventions: DEVICE: Monitoring Device|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dreaming and EEG Changes During Anaesthesia Maintained With Propofol or Desflurane
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Propofol|DRUG: desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Double-Blind, Randomized, Placebo-Controlled Study of Low Dose Oral Interferon Alfa-n3 (Human Leukocyte Derived) in ARC Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Interferon alfa-n3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Adjuvanting Viral Vectored Malaria Vaccines With Matrix M
Status: COMPLETED
Conditions: Malaria|Matrix M
Interventions: BIOLOGICAL: Control Regimen|BIOLOGICAL: Low Dose Matrix M Regimen|BIOLOGICAL: Standard Dose Matrix M Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dato-DXd|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Carboplatin|DRUG: Capecitabine|DRUG: Eribulin mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Gel Therapy for Cariogenic Oral Microflora
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: 1% Chlorhexidine Gluconate Gel|BEHAVIORAL: Surveys
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Droxidopa / Pyridostigmine in Orthostatic Hypotension
Status: SUSPENDED
Conditions: Orthostatic Hypotension
Interventions: DRUG: Droxidopa|DRUG: Pyridostigmine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of HLA Haploidentical CAR-NK Cells Targeting CD19 in the Treatment of Refractory/Relapsed B-cell NHL
Status: UNKNOWN
Conditions: B-cell Non Hodgkin Lymphoma
Interventions: BIOLOGICAL: anti-CD19 CAR-NK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab Plus 2CdA in Patients With Advanced or Relapsed Mucosa Associated Lymphoid Tissue (MALT) Lymphoma
Status: COMPLETED
Conditions: Lymphoma of Mucosa-Associated Lymphoid Tissue
Interventions: DRUG: Rituximab|DRUG: 2-CdA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT