pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Oral Versus IV Proton Pump Inhibitor in High-risk Bleeding Peptic Ulcers After Endoscopic Hemostasis
Status: UNKNOWN
Conditions: Peptic Ulcers
Interventions: DRUG: Pantoprazole (Pantoloc)|DRUG: Lansoprazole (Takepron OD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MRI-Guided High-Definition Transcranial Direct Current Stimulation (tDCS) for Depression
Status: RECRUITING
Conditions: Depression
Interventions: DEVICE: Transcranial Direct Current Stimulation|DEVICE: Sham Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immediate-access Arteriovenous Versus Standard Arteriovenous Grafts in Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis Access Failure
Interventions: PROCEDURE: Arteriovenous Grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemodynamic Impact of the Administration of PAracetamol in Patients Hospitalized in the Intensive Resuscitation Medicine Department [PAREA]
Status: NOT_YET_RECRUITING
Conditions: Intensive Care Unit Syndrome
Interventions: DRUG: paracetamol administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of AZD1222, a Vaccine for the Prevention of COVID-19 in Immunocompromised Adults
Status: TERMINATED
Conditions: COVID-19, SARS-CoV-2
Interventions: BIOLOGICAL: AZD1222
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Hypnosis Combined to Transcranial Direct Stimulation in Pain
Status: COMPLETED
Conditions: Pain Perception|Pain Acute
Interventions: BEHAVIORAL: Hypnotic analgesia|DEVICE: a-tDCS|OTHER: Hypnotic analgesia + a-tDCS|DEVICE: s-tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Oligosaccharides and Optimizing Multiple Nutrients to Infant Formula on Growth and Development of Infants
Status: RECRUITING
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: oligosaccharides and multiple nutrients|DIETARY_SUPPLEMENT: no oligosaccharides and optimizing multiple nutrients|DIETARY_SUPPLEMENT: breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Datopotamab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Study of ASP8273 in Patients With Non-Small-Cell Lung Cancer (NSCLC) Who Have Epidermal Growth Factor Receptor (EGFR) Mutations
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: ASP8273
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Geographic Atrophy|Age-Related Macular Degeneration
Interventions: DRUG: avacincaptad pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of N-Acetylcysteine During Liver Procurement
Status: COMPLETED
Conditions: Liver Failure|Liver Failure, Acute|Liver Diseases|Carcinoma, Hepatocellular|Liver Neoplasms
Interventions: DRUG: N-acetylcystein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Different Positive Pressure Strategies in COPD Patients.
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nebulization|DEVICE: Positive expiratory pressure valve|DEVICE: Nonivasive ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Abivertinib Maleate Versus Geifitinib in Patients With Advanced Non-small Cell Lung Cancer With Sensitive EGFR Mutation
Status: UNKNOWN
Conditions: Advanced Non-small Cell Lung Cancer
Interventions: DRUG: Abivertinib Maleate Capsules|DRUG: Placebo Gefitinib Tablets|DRUG: Gefitinib Tablets|DRUG: Placebo Abivertinib Maleate Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Agreement Between Endoscopic and Histopathological Diagnosis of Colorectal Sessile Serrated Lesions.
Status: COMPLETED
Conditions: Sessile Serrated Adenoma|Colorectal Polyp|Adenoma Colon|Colorectal Cancer|Colonoscopy|Adenoma Detection Rate|Quality Indicator
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect on Back Pain and Fatigue Level of Acupressure
Status: RECRUITING
Conditions: Coronary Angiography
Interventions: OTHER: Acupressure|OTHER: Sham acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Registration of Idarucizumab for Patients With IntraCranial Hemorrhage
Status: COMPLETED
Conditions: Intracranial Hemorrhage
Interventions: DRUG: Dabigatran Etexilate Oral Capsule [Pradaxa]|DRUG: Idarucizumab 2.5 GM/50 ML Intravenous Solution [PRAXBIND]|DRUG: Vitamin K antagonist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Confocal Laser Endomicroscopy for the Diagnosis of Gastric Intestinal Metaplasia, Intraepithelial Neoplasia, and Carcinoma
Status: UNKNOWN
Conditions: Gastric Intestinal Metaplasia|Gastric Intraepithelial Neoplasia|Gastric Carcinoma
Interventions: DEVICE: Confocal laser endomicroscopy (Pentax, EG3870K)|DEVICE: Standard White-light endoscopy (Pentax, 90i)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemoembolization Using Doxorubicin in Treating Patients With Liver Cancer That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DEVICE: Drug-eluting beads loaded with doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Status: COMPLETED
Conditions: Radicular; Neuropathic, Cervical|Neck Pain
Interventions: DRUG: Triamcinolone 80mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer|Non Small Cell Lung Cancer
Interventions: DRUG: vandetanib induction|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Placebo|DRUG: Vandetanib maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Translational Immunodiagnostics in Stroke (TrImS)
Status: RECRUITING
Conditions: Acute Ischemic Stroke|Haemorrhagic Stroke|Transient Ischemic Attacks|Cardioembolic Stroke|Large-Artery Atherosclerosis (Embolus/Thrombosis)|Small Vessel Disease|Stroke of Other Determined Etiology|Stroke of Undetermined Etiology|Atrial Fibrillation|Stroke of Anterior Cerebral Artery|Stroke of Middle Cerebral Artery|Stroke of Basilar Artery
Interventions: DIAGNOSTIC_TEST: Biomarker blood draw and saliva collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Semi Fowler 30' Right Lateral on Cardiac Output in Acute Heart Failure
Status: COMPLETED
Conditions: Cardiac Output, High|Heart Failure|Pulmonary Edema With Heart Failure|Dyspnea; Cardiac|Arrythmia
Interventions: BEHAVIORAL: Semifowler 30' Right Lateral Body Position
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Oropharyngeal Cancer
Interventions: RADIATION: Radiation|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deuteporfin Tolerance and Pharmacokinetics in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: deuteporfin|DRUG: deuteporfin|DRUG: deuteporfin|DRUG: deuteporfin|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Ring (APR) Fixation Vs Posterior Ring Fixation in Tile B2 and C1 Pelvic Ring Injuries
Status: COMPLETED
Conditions: Evaluation of PR Fixation in Tile B2 and C1 Injuries
Interventions: PROCEDURE: Combined posterior and anterior ring fixation: Active comparator. Isolated posterior ring fixation: Experimental intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family and Patient Outcomes After Pediatric Intensive Care (FOREVER)
Status: COMPLETED
Conditions: Post-Intensive Care Syndrome|Anxiety|Depression|Stress Disorders, Post-Traumatic|Quality of Life|Satisfaction, Patient
Interventions: BEHAVIORAL: Hospital diaries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Bioequivalence Study of ASC-01 Placebo (Aripiprazole 0 mg/Sertraline 100 mg) and Sertraline Tablet in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|DRUG: ASC-01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait
Status: RECRUITING
Conditions: Rectal Cancer|Consolidation
Interventions: DRUG: Oxaliplatin|DRUG: 5FU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Predictors of CIN Study Series 5.0:Stability Study in Vaginal Self-samples
Status: COMPLETED
Conditions: Human Papillomavirus
Interventions: OTHER: Cervico-vaginal self-sample taken with first flocked swab|OTHER: Cervico-vaginal self-sample taken with a second flocked swab|OTHER: Cervico-vaginal self-sample taken with a HerSwab device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Automated Abdominal Binder for Orthostatic Hypotension
Status: RECRUITING
Conditions: Orthostatic Hypotension|Autonomic Failure|Pure Autonomic Failure|Multiple System Atrophy
Interventions: DEVICE: automated abdominal binder|DEVICE: Sham binder|DRUG: Placebo|DRUG: Midodrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Healthy Eating Interventions
Status: COMPLETED
Conditions: Nutrition Therapy
Interventions: BEHAVIORAL: Information provision intervention|BEHAVIORAL: information provision + flat incentive|BEHAVIORAL: Information provision + tiered incentive|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Efficacy and Safety of Ovarian Stimulation With GONAL-f® and Luveris® Starting on Day 1 Versus Day 6 in Women Undergoing Assisted Reproductive Technique
Status: TERMINATED
Conditions: Infertility|Fertility|Follicle Stimulating Hormone Deficiency
Interventions: DRUG: GONAL-f®|DRUG: Luveris®|BIOLOGICAL: Recombinant human chorionic gonadotropin (r-hCG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of TTNS and PNS on Neurogenic Overactive Bladder Symptoms in Female Patients With Multiple Sclerosis.
Status: RECRUITING
Conditions: Multiple Sclerosis|Overactive Bladder Syndrome
Interventions: DEVICE: TTNS (Transcutaneous tibial nerve stimulation)|DEVICE: PNS (Parasacral nerve stimulation)|DEVICE: Sham stimulation|BEHAVIORAL: Behavioral treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of acceXible's Automated Speech Analysis Method for the Early Detection and Monitoring of Patients With Mild Impairment or Dementia in Primary Care
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Dementia
Interventions: DEVICE: Speech analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Changes in the Brain as Borderline Patients Learn to Regulate Their Emotions
Status: COMPLETED
Conditions: Borderline Personality Disorders|Avoidant Personality Disorders
Interventions: BEHAVIORAL: Reappraisal Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Study the Effect of SC-FOS Prebiotics in Women With Polycystic Ovary Syndrome
Status: RECRUITING
Conditions: Polycystic Ovary Syndrome
Interventions: DIETARY_SUPPLEMENT: Short Chain Fructooligosaccharides|DIETARY_SUPPLEMENT: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of BI 201335 NA in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 201335 NA in single rising doses|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PI3K Delta Inhibitor in Relapsed / Refractory Autoimmune Hemolytic Anemia Patients After Receiving Two or More Lines of Therapy
Status: TERMINATED
Conditions: Autoimmune Hemolytic Anemia|Failure of Two Rounds of Treatment
Interventions: DRUG: Linperlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma
Status: COMPLETED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Oligodendroglioma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Bendamustine Hydrochloride|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choroidal Blood Flow and Progression of Age-Related Macular Degeneration in the Fellow Eye in Patients With Unilateral Choroidal Neovascularisation
Status: COMPLETED
Conditions: Regional Blood Flow
Interventions: PROCEDURE: ocular blood flow measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prasugrel Switching Study in Patients With Acute Coronary Syndrome (ACS) Who Underwent Percutaneous Coronary Intervention (PCI)
Status: COMPLETED
Conditions: Acute Coronary Syndrome (ACS)
Interventions: DRUG: Prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Needle-insertion Depth on Successful Epidurogram and Clinical Outcome in Caudal Epidural Injections
Status: TERMINATED
Conditions: Lumbosacral Radicular Pain
Interventions: PROCEDURE: new caudal injection technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Effect of Consumption of Post-harvest UV-B Treated Mushrooms on Vitamin D Status of Healthy Adults
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: 1,000 IU vitamin D2|DIETARY_SUPPLEMENT: placebo capsule|OTHER: mushrooms|OTHER: UVB-treated mushrooms, 400 IU vitamin D2|OTHER: UVB-treated mushrooms, 1,000 IU vitamin D2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Infrapopliteal Drug Eluting Angioplasty Versus Stenting
Status: COMPLETED
Conditions: Arterial Occlusive Disease
Interventions: PROCEDURE: Paclitaxel coated balloon angioplasty.|PROCEDURE: Infrapopliteal Primary Drug Eluting Stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Xolair® (Omalizumab) in Chinese Patients With Chronic Spontaneous Urticaria
Status: COMPLETED
Conditions: Chronic Spontaneous Urticaria
Interventions: DRUG: Omalizumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early ParkinSon wIth L-DOPA/DDCI and OpicapoNe (EPSILON Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson
Interventions: DRUG: Opicapone 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diode Laser and Photodynamic Therapy Vs. Ciclopirox.
Status: NOT_YET_RECRUITING
Conditions: Onychomycosis
Interventions: DEVICE: Diode laser combined with photodynamic-red laser therapy by RapidoPodia Laser Diodo®|DRUG: Ciclopirox Hydroxypropyl Chitosan (HPCH) Nail Lacquer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Single Dose Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of MEDI5884
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: MEDI5884 Dose 1|BIOLOGICAL: MEDI5884 Dose 2|BIOLOGICAL: MEDI5884 Dose 3|BIOLOGICAL: MEDI5884 Dose 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Photorefractive Keratectomy for Severe Anisometropia and Isoametropia Associated With Amblyopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Anisometropia|Hyperopia|High Myopia|Amblyopia Isometropic|Amblyopia Bilateral|High Astigmatism
Interventions: PROCEDURE: Photorefractive keratectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of FOY-305 in Patients With SARS-Cov-2 Infection (COVID-19)
Status: COMPLETED
Conditions: SARS-CoV-2 Infection (COVID-19)
Interventions: DRUG: FOY-305|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prebiotic as a Supplement of Gluten-free Diet in the Management of Celiac Disease in Children
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Synergy 1|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study in Female Subjects With Breast Cancer Receiving Aromatase Inhibitor or Tamoxifen
Status: COMPLETED
Conditions: Vasomotor Symptoms (VMS)
Interventions: DRUG: oral capsule of Q-122
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: V2 Receptor Effects on Fluid Regulation and Performance
Status: COMPLETED
Conditions: Electrolyte Imbalance|Hyponatremia|Hypernatremia
Interventions: DRUG: V2R (Vasopressin 2 receptor)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Integrase Inhibitor (MK-0518) Viral Decay
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir (MK0518)|DRUG: Placebo|PROCEDURE: Leukopheresis|PROCEDURE: Sigmoid Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children
Status: COMPLETED
Conditions: Schistosoma Haematobium|Schistosoma Mansoni
Interventions: DRUG: Praziquantel|DRUG: Artesunate + Mefloquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Versus Non-Fasting for Cardiac Implantable Electronic Devices (FastCIED Study)
Status: COMPLETED
Conditions: Cardiac Implantable Electronic Devices
Interventions: DIETARY_SUPPLEMENT: Clear fluids and food up to up to 1 hour before the procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study.
Status: COMPLETED
Conditions: Invasive Pulmonary Aspergillosis|Morality
Interventions: DIAGNOSTIC_TEST: RT-PCR for influenza
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AMT-151 in Patients With Selected Advanced Solid Tumours
Status: RECRUITING
Conditions: Advanced Solid Tumor|Advanced Cancer|Advanced Carcinoma|Ovarian Cancer|Ovarian Carcinoma|Ovarian Epithelial Cancer|Ovarian Endometrioid Adenocarcinoma|Endometrial Cancer|Endometrial Adenocarcinoma|Endometrial Serous Adenocarcinoma|Endometrial Endometrioid Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Lung Adenocarcinoma|Triple Negative Breast Cancer|Pancreatic Ductal Adenocarcinoma|Malignant Pleural Mesothelioma|Ovarian Clear Cell Carcinoma|Ovarian Clear Cell Adenocarcinoma|Ovarian Mucinous Adenocarcinoma
Interventions: DRUG: AMT-151
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contrast-Enhanced Ultrasound in Predicting Treatment Response in Patients With Liver Cancer Receiving Transarterial Chemoembolization With Drug Eluting Beads
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Perflutren Lipid Microspheres|DEVICE: Dynamic Contrast-Enhanced Ultrasound Imaging|DEVICE: Contrast-enhanced Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States
Status: COMPLETED
Conditions: Reflux Oesophagitis
Interventions: DRUG: YF476|DRUG: Ranitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Diffuse Large B-Cell Lymphoma|Glioblastoma Multiforme|Hepatocellular Carcinoma|Non-Small Cell Lung Cancer|Neuroendocrine Tumors of Non-Pancreatic Origin|Hormone Receptor-Positive Breast Cancer
Interventions: DRUG: CC-223
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Migraine
Status: RECRUITING
Conditions: Migraine Disorders
Interventions: DRUG: Botulinum toxin type A|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Specificity, Sensitivity and Clinical Correlation of CBA, RIPA and ELISA in Detecting AChR and MuSK IgG of Myasthenia Gravis
Status: COMPLETED
Conditions: Detection Autoantibody of Myasthenia Gravis
Interventions: DIAGNOSTIC_TEST: CBA Assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Tenofovir Plus Lamivudine Plus Efavirenz Regimen as First-line Antiretroviral Therapy
Status: UNKNOWN
Conditions: AIDS/HIV PROBLEM
Interventions: DRUG: TDF+3TC+EFV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Persistent Atrial Fibrillation Treatment (RAAFT-3)
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Anti Arrhythmics|PROCEDURE: Pulmonary Vein Isolation performed by Radio Frequency Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Tin Mesoporphyrin in Patients on Long Term Heme Therapy for Prevention of Acute Attacks of Porphyria
Status: COMPLETED
Conditions: Porphyria
Interventions: DRUG: heme arginate|DRUG: tin mesoporphyrin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of TheraSphere and Resection Combination Therapy in Patients With Single Large ((> 5cm, Long Diameter ) Hepatocellular Carcinoma : Exploratory Trial
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DEVICE: Theraspere
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Status: COMPLETED
Conditions: Uterine Prolapse|Bladder Diseases|Cystocele|Rectocele
Interventions: BEHAVIORAL: Pelvic floor muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel (Taxotere), Vinorelbine, and Bevacizumab, as Adjuvant Chemotherapy for Patients With Resected Stage I-III Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Bevacizumab (Avastin), Taxotere (Docetaxel), Vinorelbine Tartrate (Navelbine)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trifluridine/Tipiracil Plus Bevacizumab Versus Trifluridine/Tipiracil Monotherapy in Refractory Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: Trifluridine/Tipiracil|DRUG: Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hepatitis B Vaccine Predialysis/Dialysis Study (V232-060)
Status: COMPLETED
Conditions: Hepatitis B Virus Infection
Interventions: BIOLOGICAL: Comparator: modified process hepatitis B vaccine|BIOLOGICAL: Comparator: ENGERIX-B™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Stereotactic Fractionated Radiotherapy to the Resection Cavity in Recurrent Glioblastoma
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: RADIATION: SRT to the resection cavity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gleevec/Low-Dose Ara-C Study for Elderly Patients With AML and Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia, Myeloid|Myelodysplastic Syndromes
Interventions: DRUG: Gleevec|DRUG: Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulmonary Rehabilitation in Lung Cancer Survivors
Status: COMPLETED
Conditions: Lung Cancer|Lobectomy|Pulmonary Rehabilitation
Interventions: OTHER: Pulmonary Rehabilitation|OTHER: Usual post operative care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Treatment of C/S of Qi Stagnation and Blood-stasis Type by Moving Cupping With Bloodletting
Status: RECRUITING
Conditions: Cervical Spondylosis
Interventions: OTHER: Massage treatment|OTHER: Cupping|OTHER: Bloodletting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zonisamide Versus Topiramate in Migraine
Status: RECRUITING
Conditions: Migraine
Interventions: DRUG: Zonisamide 50 MG|DRUG: Topiramate 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury
Status: COMPLETED
Conditions: Sleep Apnea|Spinal Cord Injuries|Spasticity, Muscle|Neuropathic Pain|Cardiovascular Complication
Interventions: DEVICE: Home-based sleep screening test or hospital-unattended sleep screening test|DEVICE: Cardiovascular beat-to-beat monitoring|DEVICE: ECG monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupressure for Constipation in the Elderly
Status: COMPLETED
Conditions: Constıpatıon
Interventions: OTHER: Acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementation and Validation of the "5As Framework of Obesity Management" in Primary Care. "5AsT"
Status: COMPLETED
Conditions: Overweight and Obesity
Interventions: BEHAVIORAL: 5As Team Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects Of Ropinirole On Mood Or Mild Depression In Patients With Moderate To Severe Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome|Moderate to Severe Idiopathic Restless Legs Syndrome (RLS)
Interventions: DRUG: Ropinirole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin|DRUG: Ketamine|DRUG: Propofol|DRUG: Etomidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of Age
Status: TERMINATED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Vortioxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Docetaxel in Treating Patients With HPV-Related Oropharyngeal Cancer
Status: COMPLETED
Conditions: Human Papillomavirus Infection|Stage I Oropharyngeal Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Docetaxel|RADIATION: Hyperfractionation|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Multi-Center, Open-Label, Uncontrolled Study to Evaluate the Efficacy and Safety of Sorafenib Given Daily in Combination With Repeated 21-Day Cycles of Dacarbazine (DTIC) Chemotherapy in Subjects With Advanced Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006) + Dacarbazine (DTIC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCI-210 in the Treatment of Children and Young Adults With AutismEvaluate the Safety, Tolerability and Efficacy of SCI-210 in Children With Autism Spectrum Disorder (ASD)
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder (ASD)
Interventions: DRUG: SCI-210|DRUG: Oral CBD oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of In-the-bag Stability Between Single-piece and Three-piece Intraocular Lens
Status: COMPLETED
Conditions: Cataract
Interventions: PROCEDURE: Phacomulsification lens removal cataract surgery with single-piece Intraocular lens(IOL) implantation|PROCEDURE: Phacomulsification lens removal cataract surgery with three-piece Intraocular lens(IOL) implantation|DRUG: Subconjunctival dexamethasone|DEVICE: Viscoelastic materials|DRUG: proparacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a Combination Product for the Prevention of Veisalgia
Status: COMPLETED
Conditions: Veisalgia
Interventions: DRUG: JMI-001 (SJP-304 and SJP-223)|DRUG: SJP-304|DRUG: SJP-223|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis
Interventions: BIOLOGICAL: CABA-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Plus Bevacizumab Versus Sintilimab Plus Bevacizumab With TACE and HAIC in Unresectable Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab combined with Bevacizumab|DRUG: Sintilimab combined with Bevacizumab|PROCEDURE: Transcatheter arterial chemoembolization and hepatic arterial infusion chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Purified CD34+ Hematopoietic Stem Cell Transplantation From Alternate Donors for Patients With Severe Aplastic Anemia
Status: COMPLETED
Conditions: Aplastic Anemia
Interventions: PROCEDURE: Allogeneic stem cell transplant|DRUG: Fludarabine, Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Screening Assay for Taiwanese Population
Status: COMPLETED
Conditions: Advanced Colorectal Neoplasms|Throat Cancer|Esophageal Cancer|Gastric Cancer|Important Lower and Upper Gastrointestinal Tract Lesions
Interventions: OTHER: Fecal immunochemical test, guaiac fecal occult-blood test, and Helicobacter pylori stool antigen test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Analgesia for Total Hip Arthroplasty
Status: COMPLETED
Conditions: Regional Anesthesia
Interventions: PROCEDURE: bupivacaine 0.5% with 1:200000 adrenaline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: PROCEDURE: Biological mesh assisted perineal closure|PROCEDURE: Primary perineal closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Applicaion of Mouth Opener Combined With Electronic Video Laryngoscope in Double-lumen Intubation of Patients With Difficult Airway
Status: COMPLETED
Conditions: Difficult Airway Intubation|Double-lumen Tube
Interventions: DEVICE: laryngoscope with mouth opener|DEVICE: video laryngoscope with mouth opener
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Mind-body Intervention to Improve Body and/or Self Image
Status: COMPLETED
Conditions: Breast Cancer|Ovarian Cancer|Uterine Cancer|Cervical Cancer
Interventions: BEHAVIORAL: Hypnotic Relaxation Therapy|BEHAVIORAL: Progressive Muscle Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of Phytonutrients From Novel Preparations of Broccoli
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Common Snack Combination|OTHER: Cheesy Broccoli Snack|OTHER: Cheesy Broccoli with Daikon Radish Snack|OTHER: Uncooked Broccoli Snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Stress Cardiac Magnetic Resonance of Asymptomatic Type 2 Diabetics With Cardiovascular High Risk to Measure Empagliflozin Impact on Myocardial Blood Flow (CATCH-EM)
Status: RECRUITING
Conditions: Type 2 Diabetes|Microvascular Coronary Artery Disease
Interventions: DRUG: Empagliflozin 10 MG|DRUG: Placebo|DIAGNOSTIC_TEST: Stress Cardiac Magnetic Resonance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study
Status: COMPLETED
Conditions: Epidermolysis Bullosa Simplex|Epidermolysis Bullosa Simplex Kobner|Weber-Cockayne Syndrome
Interventions: DRUG: Sirolimus, 2%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Infection Risk of Long Dwell Period Catheters in High Risk Intensive Care Unit (ICU) Patients
Status: TERMINATED
Conditions: Burns
Interventions: DEVICE: Placement of a silver impregnated central venous catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Direct Macintosh Laryngoscopy and HugeMed Video Laryngoscope for Nasotracheal Intubation in Children
Status: COMPLETED
Conditions: Intubation; Difficult or Failed|Postoperative Pain
Interventions: DEVICE: HugeMed Videolaryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of 0.375% Ropivacaine and 0.25% Levobupivacaine for Infraclavicular Brachial Plexus Block
Status: COMPLETED
Conditions: Regional Anesthesia
Interventions: DRUG: Ropivacaine solution|DRUG: Levobupivacaine solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Outcomes From a Study of Acupuncture Treatment on Experimentally Primary Dysmenorrhea
Status: UNKNOWN
Conditions: Primary Dysmenorrhea
Interventions: PROCEDURE: acupuncture, Deqi|PROCEDURE: acupuncture, Non-Deqi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Linkage to Health and Other Services for Veterans Leaving Incarceration
Status: COMPLETED
Conditions: Linkage to Care|Homelessness|Substance Use Disorder|Mental Health
Interventions: BEHAVIORAL: Peer-support plus usual care from the Health Care for Reentry Veterans program|BEHAVIORAL: Usual care from the Health Care for Reentry Veterans program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Cervical Extension Traction With & Without Modified Cervical and Shoulder Retraction Exercises in Neck Pain
Status: UNKNOWN
Conditions: Neck Pain
Interventions: OTHER: Modified Cervical and Shoulder Retraction exercises|OTHER: Cervical Extension Traction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality Based Robotic Gait and Balance Trainer
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: Lokomat|DEVICE: Thera Trainer Balo|OTHER: Person-Specific Rehabilitation Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Artery Occlusive Diseases (PAOD) Study - Clinical Assessment
Status: WITHDRAWN
Conditions: Peripheral Artery Disease
Interventions: DIETARY_SUPPLEMENT: high dose flavanoids|DIETARY_SUPPLEMENT: low dose flavanoids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Xerostomia-optimised IMRT Versus Standard IMRT in NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma ,Xerostomia,Radiotherapy
Interventions: RADIATION: Optimised neck CTV|RADIATION: standard neck CTV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Reflexology and Generalized Stretching in Postmenopausal Females.
Status: COMPLETED
Conditions: Postmenopausal Disorder
Interventions: OTHER: REFLEXOLOGY|OTHER: GENERALIZED STRETCHING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Multiple Increasing Doses of LY2409021 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: LY2409021
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of the Effect of Instrument Assisted Soft Tissue Mobilization Technique on Fascia and Fat Tissue Thickness in Healthy Individuals.
Status: UNKNOWN
Conditions: Instrument-assisted Soft Tissue Mobilization|Flexibility|Fascia|Rehabilitation|Strength|Balance
Interventions: OTHER: Observational|OTHER: IASTM Technique Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Lymphoma|Multiple Myeloma
Interventions: DRUG: Lenalidomide|DRUG: Dexamethasone|DRUG: Dexamethasone (Oral)|DRUG: Dexamethasone (IV)|BIOLOGICAL: Elotuzumab (BMS-901608; HuLuc63)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Ibrutinib Capsules to Assess Respiratory Failure in Adult Participants With Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Pulmonary Injury
Status: COMPLETED
Conditions: CoronaVirus Induced Disease-2019 (COVID-19)
Interventions: DRUG: Ibrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WBSI Guided Personalized Delivery of TTFields
Status: RECRUITING
Conditions: GBM|Glioma Glioblastoma Multiforme|Tumor, Brain
Interventions: DIAGNOSTIC_TEST: Whole Brain Spectroscopy Imaging Array Mapping Layout
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC