pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Almonertinib Versus Osimertinib in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: Almonertinib|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study: Relaxation and Guided Imagery in Hispanic Persons Diagnosed With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Pain|Functional Status|Self-Efficacy|Distress
Interventions: BEHAVIORAL: Relaxation and Guided Imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Progenitor Biological Bandages in Burn Care (Bru_PBB)
Status: NOT_YET_RECRUITING
Conditions: Burn Injury
Interventions: DRUG: Progenitor Biological Bandages|DEVICE: Jelonet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vaginal Seeding on Infants' Body Mass Index and Allergy Risk for Caesarean-delivered Children
Status: UNKNOWN
Conditions: Overweight and Obesity|Allergy
Interventions: PROCEDURE: Vaginal seeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: r-tPA Thrombolytic Therapy in Combination With Remote Ischemic Conditioning for Acute Ischemic Stroke Recovery
Status: UNKNOWN
Conditions: Stroke, Acute
Interventions: DEVICE: ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Computer-assisted PEEK Versus Conventional Titanium Plates on Mandibular Body Fractures
Status: UNKNOWN
Conditions: Fracture Mandible|Mandibular Fractures
Interventions: PROCEDURE: Titanium plate fixation|PROCEDURE: Custom made PEEK plate fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Induction of Delivery
Status: COMPLETED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Dexamethasone|DRUG: Distilled Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Asthma: Phenotyping Exacerbations 3
Status: UNKNOWN
Conditions: Asthma Attack
Interventions: DIAGNOSTIC_TEST: Spirometry including peak flow|DIAGNOSTIC_TEST: Fractional Exhaled Nitric Oxide (FeNO)|DIAGNOSTIC_TEST: Forced Oscillation Technique (FOT)|PROCEDURE: Sputum Induction|DIAGNOSTIC_TEST: Bloods|DIAGNOSTIC_TEST: Nasal lavage|DIAGNOSTIC_TEST: Throat swab|DIAGNOSTIC_TEST: Nasal Brush.|DIAGNOSTIC_TEST: Nasal absorption|OTHER: Medical History, Demographic, and Concomitant Medications|OTHER: Sino-nasal Outcome Test|OTHER: Gastroesophageal Reflux Disease Questionnaire|OTHER: Pittsburgh Vocal Cord Dysfunction Index|OTHER: Nijmegen Questionnaire.|OTHER: Hospital Anxiety and Depression Scale|OTHER: Compliance and adherence|OTHER: Acute Asthma Quality of Life Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Colorectal Adenocarcinoma
Status: COMPLETED
Conditions: Colorectal Adenocarcinoma
Interventions: DRUG: S-8184 Paclitaxel Injectable Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protection of the Heart With Remote Ischemic Preconditioning During Heart Surgery: A Pilot Study
Status: COMPLETED
Conditions: Remote Ischemic Preconditioning|Myocardial Protection
Interventions: DEVICE: Blood Pressure Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Fortified Growing-up Milk on Growth and Micronutrient Status of Nigerian Toddlers
Status: UNKNOWN
Conditions: Malnutrition; Mild|Iron-deficiency Anemia|Nutritional Stunting|Nutritional Wasting|Nutritional Deficiency|Enterobacteriaceae Infections
Interventions: OTHER: Fortified milk Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Analgesic Efficacy and Safety of ASP0819 in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: ASP0819|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neonatal Spinal Anesthesia: Effects of the Addition of Clonidine
Status: UNKNOWN
Conditions: Spinal Anesthesia|Neonates
Interventions: DRUG: clonidine|DRUG: clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracameral Gas SF6 (Sulfur Hexafluoride) Injection for Acute Hydrops in Keratoconus
Status: COMPLETED
Conditions: Hydrops in Keratoconus
Interventions: DRUG: Gas SF6 (Sulfur Hexafluoride)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Types of Biopsy Forceps for Obtaining Cold Biopsy Polypectomy for Small Sessile Colorectal Polyps Less Than 6 mm in Diameter
Status: COMPLETED
Conditions: Colorectal Polyps
Interventions: OTHER: evaluate the effectiveness of the RJ4 biopsy forcep versus the RJ3 biopsy forcep
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mitomycin C Trabeculectomy Trial for Glaucoma in Ethiopia
Status: WITHDRAWN
Conditions: Glaucoma
Interventions: DRUG: Mitomycin-C (MMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Correlating the Tumoral Metabolic Progression Index to Patient's Outcome in Advanced Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: OTHER: FDG PET-CT|OTHER: Diffusion MRI|OTHER: Blood samples (plasma preparation and CTC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Acute Effects of Autoregulated and Non-autoregulated Blood Flow Restrictive Exercise on Indices of Arterial Stiffness
Status: COMPLETED
Conditions: Arterial Stiffness|Healthy Lifestyle
Interventions: DEVICE: Delfi Personal Tourniquet Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Endoscopic Mucosal Resection With Circumferential Incision for Colorectal Neoplasms
Status: ACTIVE_NOT_RECRUITING
Conditions: Endoscopic Mucosal Resection With Circumferential Incision
Interventions: PROCEDURE: Endoscopic mucosal resection with circumferential incision|PROCEDURE: Endoscopic submucosal dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epi-LASIK : A Confocal Microscopy Analysis of the Corneal Epithelium and Anterior Stroma.
Status: TERMINATED
Conditions: Corneal Epithelium
Interventions: PROCEDURE: Epi-LASK
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Follicular Phase Stimulation vs. Luteal Phase Stimulation in Patients Diagnosed With Suboptimal Response
Status: COMPLETED
Conditions: Improving Ovarian Stimulation; Suboptimal Responders
Interventions: DRUG: time of administration of Corifollitropin Alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Folic Acid to Improve Endothelial Sensitivity to Shear Stress in Seniors
Status: RECRUITING
Conditions: Healthy Aging|Aging|Menopause
Interventions: DIETARY_SUPPLEMENT: Folic Acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Amivantamab and Lazertinib in People With Non-Small Cell Lung Cancer (NSCLC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Non Small Cell Lung Cancer|Recurrent Non Small Cell Lung Cancer
Interventions: DRUG: Amivantamab|DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anorexia Nervosa Inpatient Physiotherapy Adapted Program
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: OTHER: Physiotherapy Adapted Program|DIAGNOSTIC_TEST: Evaluation and Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants in India
Status: COMPLETED
Conditions: Pneumococcal Infections
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine|BIOLOGICAL: 7 valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Human Study to Develop a Signature of Occupational Diesel Exhaust Exposure
Status: COMPLETED
Conditions: Experimental
Interventions: OTHER: Filtered Air Exposure|OTHER: Diesel Exhaust Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: BIOLOGICAL: FMP1/AS02A|BIOLOGICAL: RabAvert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Pain Between ACB and FNB After ACLR
Status: COMPLETED
Conditions: Pain, Postoperative|Knee Arthroscopy|Anterior Cruciate Ligament/Surgery
Interventions: PROCEDURE: Adductor canal block (active)|PROCEDURE: Femoral nerve block (active)|PROCEDURE: Femoral nerve block (sham block)|PROCEDURE: Adductor canal block (sham block)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Relative Bioavailability of Subcutaneous Bepirovirsen When Delivered From a Vial or Prefilled Syringe Fitted With a Safety Syringe Device in Healthy Adult Participants
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: Bepirovirsen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Pain
Interventions: DEVICE: ANI-guided opioid administration|OTHER: Standard opioid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CO-ADAPT: Adaptive Environments and Conversational Agent Based Approaches for Healthy Ageing and Work Ability
Status: COMPLETED
Conditions: Work Related Stress|Psychologic Adaptation
Interventions: BEHAVIORAL: SMT|DEVICE: App CA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR).
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Aflibercept-FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Information Provision During Early Gait Training Post Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Frequent instructions/feedback and an Internal Focus of Attention|OTHER: Minimal instructions/feedback and an External Focus of Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caries-preventive Effect of a Dentifrice Containing 5,000 Ppm Fluoride in Orthodontic Patients
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: toothpaste containing 5,000 ppm fluoride|OTHER: 1450 GCP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of Anacetrapib (MK0859) in Patients With Hepatic Insufficiency (MK-0859-039)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: anacetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation for Elective Awake Fiberoptic Intubation
Status: COMPLETED
Conditions: Awake Fiberoptic Intubation
Interventions: DRUG: Dexmedetomidine HCL Injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Fed Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg and Benicar HCT® Tablets 40 mg/25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Olmesartan Medoxomil and Hydrochlorothiazide Tablets 40 mg/25 mg|DRUG: Benicar HCT ® Tablets 40 mg/25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Dexketoprofen in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Postoperative Pain|Analgesia
Interventions: DRUG: Dexketoprofen Trometamol|DRUG: Ropivacaine Hydrochloride 7.5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Toujeo Versus NPH Self-titration Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine 300 UNT/ML|DRUG: Neutral protamine hagedorn insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain and Major Depressive Disorder
Status: RECRUITING
Conditions: Major Depressive Disorder|Chronic Pain
Interventions: DEVICE: Active rTMS/Active iTBS DFPLC/Sham Pain M1|DEVICE: Active rTMS/Active iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spectroscopy in Diagnosing Dysplasia and Neoplasia in the Cervix in Women Undergoing Colposcopy
Status: COMPLETED
Conditions: Cervical Cancer|Precancerous Condition
Interventions: OTHER: fluorophotometry|PROCEDURE: colposcopic biopsy|PROCEDURE: colposcopy|PROCEDURE: light-scattering spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluating RISQ System Implementation in Acutely Malnourished Children in Chad (CRIMSON)
Status: RECRUITING
Conditions: Severe Acute Malnutrition
Interventions: OTHER: The Responses to Illness Severity Quantification (RISQ) System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Effectiveness of ILIxadencel Administered Into Tumors in Combination With Checkpoint Inhibitor (CPI) in Patients With ADvanced Cancer
Status: TERMINATED
Conditions: Carcinoma, Squamous Cell of Head and Neck|Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: ilixadencel|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Chemotherapy Induced Nausea and Vomiting in Breast Cancer Patients.
Status: UNKNOWN
Conditions: Emesis
Interventions: DRUG: Dexamethasone, Ondansetron, Aprepitant|OTHER: Arm A: Standard Anti-emetic regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Analgesia for Colonic Resection Using an Enhanced Recovery After Surgery (ERAS) Program
Status: COMPLETED
Conditions: Colon Cancer|Inflammatory Bowel Diseases|Diverticulitis
Interventions: DRUG: Spinal analgesia|DRUG: Patient Control Analgesia (PCA) Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Analgesic Effects of Three Ultrasound Guided Regional Anesthetic Techniques in Pediatrics
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Usefulness of Therapeutic Drug Monitoring of Colistin in Patients Treated With Colistin.
Status: COMPLETED
Conditions: Multidrug-resistant Gram-negative Bacteria Infection
Interventions: OTHER: Therapeutic drug monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Compare the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Placebo on Symptoms in Patients With Allergic Rhinitis Within/Out of Season
Status: COMPLETED
Conditions: Atopy|Rhinitis
Interventions: DRUG: cetericine and pseudoephedrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Research Study of NNC0165-1875 Alone or Together With Semaglutide in People Who Are Overweight or Obese
Status: COMPLETED
Conditions: Obesity and Overweight
Interventions: DRUG: NNC0165-1875|DRUG: Placebo (NNC0165-1875)|DRUG: Semaglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation
Status: UNKNOWN
Conditions: Intubation Complication|PreTerm Birth
Interventions: DEVICE: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Anginera In Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Anginera, a human tissue replacement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Care Pathways for Bowel Symptoms in Rectal Cancer patients_development of E-diary
Status: RECRUITING
Conditions: Rectal Cancer|LARS - Low Anterior Resection Syndrome
Interventions: DIAGNOSTIC_TEST: bowel e-diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess the Safety, Reactogenicity and Immune Response of GlaxoSmithKline (GSK) Biologicals' Investigational Respiratory Syncytial Virus (RSV) Vaccine (GSK3844766A) in Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV Vaccine (GSK3844766A) unadjuvanted low dose|BIOLOGICAL: RSV Vaccine (GSK3844766A) low dose adjuvanted with AS01E|BIOLOGICAL: RSV Vaccine (GSK3844766A) low dose adjuvanted with AS01B|BIOLOGICAL: RSV Vaccine (GSK3844766A) unadjuvanted medium dose|BIOLOGICAL: RSV Vaccine (GSK3844766A) medium dose adjuvanted with AS01E|BIOLOGICAL: RSV Vaccine (GSK3844766A) medium dose adjuvanted with AS01B|BIOLOGICAL: RSV Vaccine (GSK3844766A) unadjuvanted high dose|BIOLOGICAL: RSV Vaccine (GSK3844766A) high dose adjuvanted with AS01E|BIOLOGICAL: RSV Vaccine (GSK3844766A) high dose adjuvanted with AS01B|DRUG: Placebo (Saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Relative Bioavailability Study of Citalopram 40 mg Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Citalopram HBr 40 mg tablets, single dose|DRUG: CelexaTM 40 mg tablets, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: An Open, Multicenter, Randomized, Dose-Ranging Study of Azithromycin in the Treatment of Disseminated Mycobacterium Avium-Intracellulare Complex Infection (MAC) in Patients With Acquired Immune Deficiency Syndrome (AIDS)
Status: COMPLETED
Conditions: Mycobacterium Avium-Intracellulare Infection|HIV Infections
Interventions: DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Interdisciplinary Care Compared to Usual Care in Patients With Immune-Mediated Inflammatory Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis|Psoriatic Arthritis|Axial Spondyloarthritis|Hidradenitis Suppurativa|Crohn Disease|Ulcerative Colitis
Interventions: OTHER: Interdisciplinary management|OTHER: Usual-care management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Post-approval Study of Transcarotid Artery Revascularization in Standard Risk Patients With Significant Carotid Artery Disease
Status: RECRUITING
Conditions: Carotid Artery Diseases
Interventions: PROCEDURE: Transcarotid Artery Revascularization (TCAR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls
Status: TERMINATED
Conditions: Pre-diabetes|Obesity
Interventions: DRUG: Chronic salsalate|DRUG: Acute Salsalate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Protein Pacing Effects on HbA1c in Type 2 Diabetics
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes|HbA1c|Protein Intake
Interventions: DIETARY_SUPPLEMENT: PP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Performance Validation of Electronic Thermometer and Infrared Thermometers
Status: ACTIVE_NOT_RECRUITING
Conditions: Febrile|Healthy
Interventions: DEVICE: Infrared Forehead Thermometer (GE-TF03)|DEVICE: Infrared Ear Thermometer (GE-TE06)|DEVICE: Electronic Thermometer (MT-B321FB)|DEVICE: Electronic Thermometer (MT-B231)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer
Status: UNKNOWN
Conditions: Breast Cancer|Lymphedema|Perioperative/Postoperative Complications|Radiation Fibrosis
Interventions: DRUG: hyperbaric oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Healthy
Interventions: DRUG: Intranasal insulin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction Caused by Spinal Cord Injury
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: DRUG: Vardenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Fluticasone Propionate on Ocular Allergy Symptoms
Status: COMPLETED
Conditions: Allergic Rhinitis|Seasonal Allergic Rhinitis
Interventions: DRUG: Fluticasone propionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Long-term Safety Study of Eltrombopag in Pediatric Patients With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: Eltrombopag Tablets|DRUG: Eltrombopag PfOS
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Status: UNKNOWN
Conditions: Autism
Interventions: OTHER: Probiotic, Lactobacillus plantarum PS128|OTHER: Placebo, microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Precision and Agreement of SS-1000 and Pentacam in a Repeatability and Reproducibility Trial
Status: COMPLETED
Conditions: Evaluate the Agreement and Precision of Device SS-1000 and the Predicate Device the Pentacam in a Reproducibility and Repeatability Trial
Interventions: DEVICE: CASIA Cornea/Anterior Segment OCT SS-1000
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Impact of Zinc and Vitamin D3 Supplementation on the Survival of Aged Patients Infected With COVID-19
Status: WITHDRAWN
Conditions: SARS-CoV 2
Interventions: DIETARY_SUPPLEMENT: Zinc gluconate|DIETARY_SUPPLEMENT: 25-OH cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Exchanges With Avocado and Mango in Pre-diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Pre Diabetes|Vascular Stiffness|Vascular Dilation|Cognitive Change|Retinal Vascular
Interventions: OTHER: Meals + snacks: control|OTHER: Meals + snacks: Avocado mango
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase I/II Study of TSU-68 for Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Orantinib (TSU-68)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized, Placebo-Controlled, Double-Blinded, Phase I Trial to Evaluate the Safety and Immunogenicity of Live Recombinant Canarypox ALVAC-HIV vCP205 Combined With GM-CSF in Healthy, HIV-1 Uninfected Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: APL 400-047|BIOLOGICAL: ALVAC-HIV MN120TMG (vCP205)|DRUG: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Acrosome Reaction Induction Prior to ICSI
Status: UNKNOWN
Conditions: Assisted Reproductive Technique|ICSI|Acrosome Reaction|Pregnancy Outcome
Interventions: OTHER: Acrosome Reaction induction|OTHER: capacitation in incubation medium prior to ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Prolonged Exposure Therapy|DRUG: Pharmacotherapy with paroxetine or venlafaxine XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Acute Tracheitis and Laryngitis With Essential Oils of Aromatic Plants
Status: COMPLETED
Conditions: Viral Laryngitis|Viral Tracheitis
Interventions: DIETARY_SUPPLEMENT: mixture of aromatic essential oils.|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Assessment of IRE of Localized Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DEVICE: Focal irreversible electroporation of the prostate cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Anesthetic Techniques for Implant Placement
Status: COMPLETED
Conditions: Edentulous Jaw|Dental Implant|Anesthesia, Local
Interventions: PROCEDURE: Dental Implant Placement in the posterior mandible
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TMC435 in Combination With PSI-7977 (GS7977) in Chronic Hepatitis C Genotype 1-Infected Prior Null Responders To Peginterferon/Ribavirin Therapy or HCV Treatment-Naive Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435|DRUG: PSI-7977 (GS7977)|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndromes (MDS)
Interventions: DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate a Leukapheresis Treatment in Patients With Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DEVICE: Active TLA Gut™ column|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and Safety of RESTORE DEB and SeQuent® Please in Chinese Patient With Coronary In-stent Restenosis
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: Drug Eluting Balloon Catheters(RESTORE DEB）|DEVICE: Drug Eluting Balloon Catheters(SeQuent® Please）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-tumour Effects & Tolerability of Faslodex Alone or in Combination With Arimidex in Post Menopausal Women Prior to Surgery for Primary Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Anastrazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety, Tolerability and Efficacy of Bilastine Ophthalmic Solution 0.6% in Children
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Bilastine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: metformin|DRUG: Melatonin|DRUG: Toremifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy in the Treatment of Malignant Intracranial Tumors
Status: WITHDRAWN
Conditions: Malignant Intracranial Tumors|Glioblastoma Multiforme|Anaplastic Astrocytomas|Anaplastic Oligodendrogliomas|Anaplastic Ependymoma
Interventions: PROCEDURE: Photodynamic therapy using Photosan and LumaCare™ Lamp Model LC-122M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial on Booster Immunization of Two COVID-19 Vaccines Constructed From Different Technical Routes
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Prototype and Omicron BA.4/5 Bivalent Recombinant COVID-19 Vaccine(Adenovirus Type 5 Vector) For Inhalation|BIOLOGICAL: Bivalent COVID-19 mRNA Vaccine|BIOLOGICAL: Recombinant COVID-19 Vaccine (Adenovirus Type 5 Vector) For Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Zika-Vaccine Dose Finding Study Regarding Safety, Immunogenicity and Tolerability (V186-001)
Status: COMPLETED
Conditions: Zika Virus
Interventions: BIOLOGICAL: MV-ZIKA|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Digital Rehabilitation (SIMPLI.REHAB) in Hand Arthritis
Status: NOT_YET_RECRUITING
Conditions: Arthritis, Psoriatic|Arthritis, Rheumatoid|Deformity, Hand|Limitation, Mobility|Hand Arthritis|Hand Deformity
Interventions: OTHER: Digital Rehabilitation|OTHER: Conventional Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lipid-lowering Effect of Plant Stanol Ester Yoghurt Drinks
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipidemias|Dyslipidemias
Interventions: OTHER: 1.6 g plant stanols|OTHER: 2 g plant stanols|OTHER: 1.6 g plant stanols and camelina oil|OTHER: 2 g plant stanols and camelina oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Standard Ballroom and Latin Dance Program in Type 2 Diabetes and Obesity
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: BEHAVIORAL: Dance program|BEHAVIORAL: Self-selected physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Tolerability Study of Liquid Alpha1 Proteinase Inhibitor (API) in Subjects With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: BIOLOGICAL: CR002 Liquid API|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Stretching Versus Post Isometric Relaxation Techniques On Shoulder Disability In Athletes
Status: COMPLETED
Conditions: Glenohumeral Internal Rotation Deficit
Interventions: OTHER: POST ISOMTERIC RELAXATION TECHNIQUE|OTHER: NOVEL STRETCHING
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trauma-informed Approach to Timely Detection and Management of Early Postpartum Hypertension
Status: RECRUITING
Conditions: Postpartum Hypertension
Interventions: OTHER: Remote Medical Model (RMM)|OTHER: Community Health Model (CHM)|OTHER: SoC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy|PROCEDURE: Laparoscopic Roux-en-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: APSS-33-00: A Multicenter, Pilot Study of Autologous Protein Solution (APS) in Knee Osteoarthritis (OA)
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: APS|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Efficacy, Safety, and Immunogenicity of GME751 and EU-authorized Keytruda in Adult Participants With Untreated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Metastatic NSCLC
Interventions: DRUG: GME751|DRUG: Keytruda-EU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation on Motor Function in Parkinson's Disease
Status: UNKNOWN
Conditions: Idiopathic Parkinsons Disease
Interventions: DEVICE: experimental group - tDCS|DEVICE: Control group (tDCS sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Efficacy of the Felix NeuroAI Wristband in Essential Tremor
Status: RECRUITING
Conditions: Essential Tremor
Interventions: DEVICE: Felix NeuroAI Wristband|DEVICE: Sham Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Third-line cART Regimen in Cambodia (3DICAM)
Status: UNKNOWN
Conditions: HIV/AIDS
Interventions: DRUG: Dolutegravir + Darunavir/ritonavir + optimized NRTI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Estrogen Receptor Positive Breast Cancer|Progesterone Receptor Positive Tumor|Recurrent Breast Carcinoma|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIB Breast Cancer|Stage IIIA Breast Cancer
Interventions: DRUG: Exemestane|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Oophorectomy|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|DRUG: Tamoxifen|DRUG: Triptorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2951742 in Participants With Mild to Moderate Osteoarthritis Knee Pain
Status: TERMINATED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: LY2951742|OTHER: Placebo- oral|OTHER: Placebo - SC|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combating Physical Inactivity Pandemic in Kindergartens
Status: RECRUITING
Conditions: Physical Activity|Cardiorespiratory Fitness
Interventions: OTHER: Usual Care Control|BEHAVIORAL: Physical Activity Enhanced Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Integrative Nutrition Care Plan for the Patient With Liver and Colorectal Cancer
Status: COMPLETED
Conditions: Malnutrition|Cancer of Colon|Cancer of Liver|Nutrition Aspect of Cancer
Interventions: BEHAVIORAL: Nutritional consultant|DIETARY_SUPPLEMENT: Nutritional consultant + High-calorie, high-protein liquid nutrition supplement|COMBINATION_PRODUCT: Nutritional consultant + Liquid supplement + Powdered supplement 1 and 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners
Status: RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Questionnaires|BEHAVIORAL: Meditation and Discussion Sessions|BEHAVIORAL: Cancer-Related Discussion Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy
Status: TERMINATED
Conditions: Bowel Obstruction
Interventions: DRUG: IV morphine sulfate or Sponsor-approved equivalent|DRUG: EXPAREL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of the Kinesio Tape on the Muscle Power Performance of Elite Weightlifters
Status: COMPLETED
Conditions: Muscle Power Performance
Interventions: OTHER: Kinesio Tape original brand (Kinesio® Tex GoldTM finger print, black, Georgia, Albuquerque).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma
Status: RECRUITING
Conditions: Leiomyosarcoma
Interventions: DRUG: Dinutuximab Beta, Zoledronic acid, Interleukin-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Implementation and Effectiveness of IPP-HPV
Status: COMPLETED
Conditions: HPV Vaccination
Interventions: DRUG: HPV vaccine|BEHAVIORAL: Inpatient Postpartum HPV Immunization Quality Improvement Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor
Status: UNKNOWN
Conditions: PD-1 Antibody|CAR-T Cells|Advanced Malignancies
Interventions: BIOLOGICAL: HerinCAR-PD1 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Study of Brain Protection During Aortic Arch Replacement
Status: COMPLETED
Conditions: Aneurysm of Aortic Arch
Interventions: PROCEDURE: Retrograde brain perfusion|PROCEDURE: Antegrade brain perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Bioavailability From Cereal-based Foods
Status: UNKNOWN
Conditions: Iron Bioavailability
Interventions: OTHER: Control Porridge|OTHER: Reference Porridge A|OTHER: Test Porridge B|OTHER: Test Porridge C|OTHER: Test Porridge D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of the Anti-inflammatory Effect of Heparin Infusion Versus Subcutaneous Injection in Septic Patients
Status: COMPLETED
Conditions: Sepsis|Critical Illness
Interventions: DRUG: Heparin Infusion|OTHER: subcutaneous heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CKD-396 Drug-drug Interaction Study(B) (CKD-396 DDI(B) P1)
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Januvia Tab. 100mg|DRUG: Januvia Tab. 100mg + Duvie Tab. 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opium Tincture Against Chronic Diarrhea - Healthy
Status: COMPLETED
Conditions: Chronic Diarrhea
Interventions: DRUG: Opium tincture|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adjusted Ventilatory Assist (NAVA-NIV) in Infants: Short-term Physiological Study
Status: UNKNOWN
Conditions: Acute Respiratory Failure
Interventions: DEVICE: Noninvasive NAVA ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DRUG: Azathioprine OR Mesalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Concomitant Modulated Electro-hyperthermia in HER2-negative Breast Cancer
Status: RECRUITING
Conditions: HER2-negative Breast Cancer
Interventions: DEVICE: Oncotherm EHY-2030|DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Cyclophosphamide/Doxorubicin|PROCEDURE: Breast cancer removal surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT