pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Almonds on Glycemia in Adults With Elevated Hemoglobin A1c Concentrations
Status: ACTIVE_NOT_RECRUITING
Conditions: Glucose Intolerance|Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions: OTHER: Almond|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Imaging of Coronary Plaques in Participants Treated With Evolocumab
Status: COMPLETED
Conditions: Coronary Artery Disease (CAD)
Interventions: DRUG: Evolocumab|DRUG: Placebo|DRUG: Statin therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diaphragm Protective Ventilation in the Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness|Muscle Weakness|Muscle Damage|Respiration, Artificial|Respiratory, Diaphragm
Interventions: OTHER: Titration of support level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endotherapy for Painless Chronic Pancreatitis
Status: UNKNOWN
Conditions: Pancreatitis, Chronic|Exocrine Pancreatic Insufficiency|Abdominal Pain|Cholangiopancreatography, Endoscopic Retrograde
Interventions: PROCEDURE: extracorporeal shock wave lithotripsy and endoscopic drainage of the main pancreatic duct|DRUG: pancreatic enzyme(Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose Tablets, Glucophage, Glimepirde Tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Association of Miltefosine and Pentoxifylline to Treat Mucosal and Cutaneous Leishmaniasis: A Clinical Trial in Brazil
Status: ACTIVE_NOT_RECRUITING
Conditions: Leishmaniasis
Interventions: DRUG: Meglumine antimoniate|DRUG: Miltefosine|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Bevacizumab in Combination With Chemotherapy in Previously Treated Metastatic Breast Cancer (RIBBON 2)
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Bevacizumab|DRUG: Placebo|DRUG: Standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MK1903 in Patients With Dyslipidemia (MK1903-004)
Status: COMPLETED
Conditions: Dyslipidemia
Interventions: DRUG: MK1903|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of HSA or Saline Diluent on Immunotherapy Extract Stability as Determined by Graded ID Skin Tests
Status: WITHDRAWN
Conditions: Allergic Rhinitis
Interventions: DRUG: saline with 1mg/ml Histamine base|DRUG: diluent, saline with HSA--phenol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Liraglutide on Weight Loss in Patients Who Have Undergone Revisional Bariatric Surgeries.
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: DRUG: Liraglutide Pen Injector [Saxenda]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity
Status: NOT_YET_RECRUITING
Conditions: Obesity, Childhood|Diet, Healthy|Body Weight Changes
Interventions: BEHAVIORAL: Whole Foods MyPlate Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Lenvatinib, Tislelizumab Combined With RALOX Regimen HAIC in Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Lenvatinib, Tislelizumab Combined with RALOX Regimen HAIC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [123I] MNI-340 and SPECT as a Marker of Beta-Amyloid Protein Deposition
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: 123-I MNI-340
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Smoking Relapse Prevention in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Smokers
Interventions: DRUG: bupropion + nicotine patch + nicotine gum or lozenges|DRUG: Placebo pill + placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Transplantation of Mesenchymal Stem Cell in Patients With ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: intra venous injection of stem cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics)
Status: COMPLETED
Conditions: Brain Metastasis|Spinal Tumors|Lung Tumors|Ependymoma
Interventions: RADIATION: SBRT treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Tipranavir/Ritonavir and Its Metabolites in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 14C-Tipranavir|DRUG: Tipranavir|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Assess Pharmacokinetics of Metadoxine (MG01CI) 1400 mg, Administered to Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: Metadoxine (MG01CI )
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Model SC9 IOL Compared to the Model LI61SE IOL (Bausch & Lomb)
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: Model SC9|DEVICE: Model LI61SE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Hemopatch Safety and Efficacy Evaluation Versus Standard Practice for Sealing the Dura in Cerebrospinal Fluid Leaks
Status: COMPLETED
Conditions: Surgery
Interventions: DEVICE: HEMOPATCH|DEVICE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: ICP-022|DRUG: ICP-022|DRUG: ICP-022|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of ALXN1840 on the Metabolism of a CYP2C9 Substrate in Healthy Participants.
Status: COMPLETED
Conditions: Wilson Disease
Interventions: DRUG: ALXN1840|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips
Status: COMPLETED
Conditions: Alveolar Bone Resorption
Interventions: PROCEDURE: Horizontal alveolar bone augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder
Interventions: DRUG: Bifico (Live combined bifidobacterium,Lactobacillus and Enterococcus capsules, Oral)|DIETARY_SUPPLEMENT: Dietary fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intensive Blood Pressure Control in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease
Status: RECRUITING
Conditions: Small Vessel Cerebrovascular Disease|Stroke
Interventions: OTHER: Intensive treatment|OTHER: Standard treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Feasibility of Developing Personalized Breast Cancer Radiotherapy Assistive Device With 3D Printing
Status: ENROLLING_BY_INVITATION
Conditions: Breast Neoplasms|Breast Cancer|Left Sided Breast Cancer
Interventions: DEVICE: PERSBRA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Peri-implant Mucositis in Humans
Status: COMPLETED
Conditions: Peri-implant Mucositis|Gingivitis
Interventions: BEHAVIORAL: interruption of oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adjuvant Therapy Based on Pathologic Response After Neoadjuvant Encorafenib Binimetinib in Melanoma
Status: RECRUITING
Conditions: Melanoma Stage III|Melanoma Stage IV|BRAF V600 Mutation
Interventions: DRUG: Encorafenib Pill|DRUG: Binimetinib Pill|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Topical Corticosteroid Use on Insulin Sensitivity and Bone Turnover
Status: COMPLETED
Conditions: Atopic Dermatitis|Atopic Eczema
Interventions: DRUG: Betnovate, betamethasone dipropionate ointment 0.1% and placebo|DRUG: Protopic, tacrolimus ointment 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Preventive Effects of Cetylpyridinium Chloride on SarcopeniaStudy
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: cetylpyridinium chloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics
Interventions: DRUG: JNJ-42165279 2.5 - 500 mg oral|DRUG: Placebo|DRUG: JNJ-42165279 100 mg oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zoledronic Acid and Positron Emission Tomography in Treating Patients With Advanced Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Metastatic Cancer
Interventions: OTHER: 3'-deoxy-3'-[18F]FLT|PROCEDURE: Single photon emission computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilates and Dance to Breast Cancer Patients Undergoing Treatment
Status: COMPLETED
Conditions: Breast Cancer|Quality of Life|Lymphedema|Fatigue|Depressive Symptoms|Body Image|Self Esteem|Optimism|Sexual Function Disturbances|Stress|Sleep Disturbance|Pain|Muscular Weakness|Postural Balance|Range of Motion|Cardiorespiratory Fitness
Interventions: OTHER: Dance|OTHER: Pilates
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brigatinib Post Definitive Chemo-radiotherapy in Patients With ALK-fusion Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: NSCLC, Stage III|ALK-rearrangement
Interventions: DRUG: Brigatinib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Decreasing Respiratory Rate on Lung Injury Biomarkers in ARDS Patients
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Respiration, Artificial|Ventilator-Induced Lung Injury
Interventions: PROCEDURE: Respiratory rate modification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adductor-Canal-Blockade Versus the Femoral Nerve Block Effect on Muscle Strength and Mobilization in Healthy Volunteers
Status: COMPLETED
Conditions: Muscle Strength|Healthy Volunteers
Interventions: PROCEDURE: Adductor-Canal-Blockade|PROCEDURE: The femoral nerve block|PROCEDURE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness and Safety of Tiotropium and Olodaterol in Comparison to Triple Therapy
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Tiotropium and Olodaterol (Tio+Olo)|DRUG: Long-acting beta2-agonist and Inhaled corticosteroids (LABA and ICS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Evaluation of the Pelvis in Women With Suspected Endometriosis Scheduled for Laparoscopic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Gynecologic Disease|Endometriosis|Endometriosis, Rectum|Endometriosis of Colon|Endometriosis of Vagina|Endometriosis Rectovaginal Septum|Endometriosis of Bladder|Surgery
Interventions: PROCEDURE: Ultrasound evaluation of DE
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Dexamethasone on Common Bile Duct Cannulation Time
Status: RECRUITING
Conditions: Common Bile Duct Diseases|Common Bile Duct Calculi|Common Bile Duct Stricture|Common Bile Duct Neoplasms|Common Bile Duct Dilatation
Interventions: DRUG: Dexamethasone 4mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enteric-coated Mycophenolate Sodium (Myfortic®) in Heart Transplant Recipients
Status: COMPLETED
Conditions: Gastrointestinal Symptoms|Heart Transplantation
Interventions: DRUG: Mycophenolate Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FASTing-like Approach and Maintenance IMMunotherapy in ES-SCLC Patients Not Progressing on Chemoimmunotherapy Induction
Status: NOT_YET_RECRUITING
Conditions: Small Cell Lung Carcinoma
Interventions: DIETARY_SUPPLEMENT: Cyclic, 5-day calorie restriction|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mind-Body Medicine and Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: Mind/Body Medicine Course 1|BEHAVIORAL: Mind/Body Medicine Course 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of Risperidone 1.0 mg Tablets of Torrent Pharmaceuticals Limited., India and Risperdal® (Risperidone) 1.0 mg Tablets of Janssen Pharmaceutical Products, LP, USA, in Healthy Human Adult Subjects, Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC
Status: NOT_YET_RECRUITING
Conditions: Nasopharyngeal Carcinoma|TNF|Chemo-radiotherapy
Interventions: DRUG: 5-fu|DRUG: Cisplatin|RADIATION: Radiotherapy|DRUG: TNF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Methods of Screening for Woman Abuse in Health Care Settings.
Status: COMPLETED
Conditions: Domestic Violence
Interventions: PROCEDURE: Woman Abuse Screening Tool|PROCEDURE: Partner Violence Screen|PROCEDURE: Computerized screening|PROCEDURE: Face to face screening|PROCEDURE: Written screening on forms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)
Status: COMPLETED
Conditions: Graft-versus-host Disease|Acute-graft-versus-host Disease
Interventions: DRUG: Defibrotide|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of a 2-dose Regimen of a Multivalent Human Papillomavirus (HPV) Vaccine (V503), Administered to 9 to 14 Year-olds and Compared to Young Women, 16 to 26 Years Old (V503-010)
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: BIOLOGICAL: V503 (9-valent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine Influsplit™ Tetra (Fluarix™ Tetra) (GSK2321138A) When Co-administered With Pneumovax™ 23 in Adults 50 Years of Age and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influsplit™ Tetra (Fluarix™ Tetra)|BIOLOGICAL: Pneumovax™ 23|BIOLOGICAL: Placebo (Saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intragastric Injections of Botox for the Treatment of Obesity
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity, Morbid
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Telatinib in Combination With Chemotherapy in Subjects With Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Cisplatin, Capecitabine, Telatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hand/Eyes/Mouth Behavior Management Technique During Local Anesthesia in Preschool Children
Status: COMPLETED
Conditions: Dental Anxiety|Pain|Infant Behavior|Heart Rate and Rhythm Disorders
Interventions: PROCEDURE: inferior alveolar and lingual nerve block procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glutathione Metabolism in Adolescents With Type 1 Diabetes - Study A
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Cysteine isotope infusion at normoglycemia vs hyperglycemia|DRUG: Regular Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vitamin E Versus Placebo for the Treatment of Non Diabetic Patients With Nonalcoholic Steatohepatitis
Status: COMPLETED
Conditions: NASH (Non-Alcoholic Steatohepatitis)
Interventions: DRUG: Vitamin E softgel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: OMNIA Efficacy on Body Fat Mass Reduction
Status: TERMINATED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: Omnia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Split-belt Treadmill Training for Freezing of Gait in Parkinson's Disease
Status: ENROLLING_BY_INVITATION
Conditions: Parkinson Disease|Freezing of Gait|Split-belt Treadmill
Interventions: BEHAVIORAL: Split-belt treadmill training|BEHAVIORAL: Complex task practice|BEHAVIORAL: Static balance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ABT-199 Plus Ibrutinib and Rituximab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsed Diffuse Large B-Cell Lymphoma|Refractory Diffuse Large B-Cell Lymphoma
Interventions: DRUG: ABT-199|DRUG: Ibrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-calorie Diet and Body Composition Prior to Roux-en-Y Gastric Bypass
Status: COMPLETED
Conditions: Morbid Obesity|Liver Fat
Interventions: DIETARY_SUPPLEMENT: Liquid formula low-calorie diet (LCD)|PROCEDURE: Roux-en-Y gastric bypass (RYGB)|OTHER: Control diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trastuzumab and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Women With Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel|DRUG: tamoxifen citrate|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ketogenic Diet: a Novel Metabolic Strategy to Treat Lymphedema Patients?
Status: RECRUITING
Conditions: Lymphedema|Ketogenic Dieting
Interventions: DIETARY_SUPPLEMENT: Ketogenic diet|DIETARY_SUPPLEMENT: Isocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Laser Acupuncture Treatment on Chronic Facial Paralysis
Status: COMPLETED
Conditions: Bell Palsy|Idiopathic Facial Paralyses
Interventions: OTHER: Laser acupuncture therapy|OTHER: Sham laser acupuncture therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of NovoSeven® in Haemophilia - Joint Bleeds
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A With Inhibitors|Haemophilia B With Inhibitors
Interventions: DRUG: eptacog alfa (activated)|DRUG: Feiba VH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiotherapy Re-education of Pre-activation of the Transverse Abdominis in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Non-specific Low-Back Pain
Interventions: OTHER: Physiotherapy re-education program|OTHER: Conventional treatment by GP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Pharmacokinetics of SHR1459 in Patients With Recurrent Replased/Refractory Mature B Cell Neoplasmstumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Mature B Cell Neoplasms
Interventions: DRUG: SHR1459
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Propranolol/Carvedilol Versus Atenolol/Bisoprolol/Sotalol
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: DRUG: Propranolol or Carvedilol|DRUG: Atenolol, Bisoprolol or Sotalol
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Albendazole and Levamisole Against STH on Unguja
Status: COMPLETED
Conditions: Ascariasis|Trichuriasis
Interventions: DRUG: Albendazole|DRUG: Levamisole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Single-center, Phase 1/ 2 Study of Chemoradiotherapy and AT-101 in Patients With Locally Advanced Esophageal or Gastroesophageal Junction Cancer
Status: TERMINATED
Conditions: Locally Advanced Esophageal or GE Junction Cancer
Interventions: DRUG: AT-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Moderately to Severely Active Ulcerative Colitis (MK-7240-005)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Tulisokibart|DEVICE: Companion Diagnostic (CDx) Testing|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of IDP-122 in the Treatment of Participants With Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: IDP-122 Lotion|DRUG: IDP-122 Vehicle Lotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Tailored Cognitive Behavioral Therapy for Adolescent and Young Adult Cancer Patients
Status: TERMINATED
Conditions: Depression, Anxiety|Cancer
Interventions: BEHAVIORAL: Beating the Blues (BtB)|BEHAVIORAL: Entertain Me Well (EMW)|BEHAVIORAL: Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial of New Hypothermic Oxygenated Perfusion System Versus Static Cold Storage
Status: UNKNOWN
Conditions: Liver Diseases|Kidney Diseases
Interventions: DEVICE: Kidney-Hypothermic oxygenated|DEVICE: Liver-Hypothermic oxygenated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI
Status: UNKNOWN
Conditions: Atrial Fibrillation|Arterial Hypertension
Interventions: PROCEDURE: Redo PVI|PROCEDURE: PVI + RDN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Transcatheter Aortic Valve Implantation in Oncology Patients With Severe Aortic Stenosis
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Malignancy
Interventions: DEVICE: Native aortic valve|PROCEDURE: Transcatheter aortic valve implantation (TAVI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study, Called UV Population, to Learn More About the Safety of the Study Drug Ultravist, Which is Given to Get Clearer X-ray Pictures, in People of Different Sexes, Races, and From Different Countries/Regions
Status: COMPLETED
Conditions: Contrast Enhanced X-ray Based Examination
Interventions: DIAGNOSTIC_TEST: Iopromide (Ultravist, BAY86-4877)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Magrolimab|DRUG: Venetoclax|DRUG: Azacitidine|DRUG: Cytarabine|DRUG: Daunorubicin|DRUG: Idarubicin|DRUG: Steroidal Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Clinical Trial to Evaluate and Compare Safety and Pharmacokinetic Characteristics After Administration of the DWJ1439, DWJ1464, DWC202108 or DWC202109 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Subject
Interventions: DRUG: Ursodeoxycholic Acid 250 Mg Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Neoplasm|Breast Tumor|Cancer of the Breast
Interventions: RADIATION: Proton Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial to Evaluate VLP Peanut in Healthy and Peanut Allergic Subjects
Status: RECRUITING
Conditions: Peanut Allergy
Interventions: BIOLOGICAL: VLP Peanut|BIOLOGICAL: Placebo|BIOLOGICAL: VLP Peanut
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Lung Cancer or Mesothelioma (Pegathor Lung 202)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pleural Mesothelioma|Non-small Cell Lung Cancer
Interventions: DRUG: THOR-707|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregabalin and Radicular Pain Study (PARPS)
Status: COMPLETED
Conditions: Cervical Spondylosis|Cervical Spondylotic Myelopathy|Cervical Spondylotic Radiculopathy
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-Dose Study of Tivozanib in Subjects With Hepatic Impairment and Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Tivozanib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tracking the Brain in Myotonic Dystrophies: a 5-year Longitudinal Follow-up Study
Status: COMPLETED
Conditions: Myotonic Dystrophy 1|Myotonic Dystrophy 2
Interventions: OTHER: medical history|OTHER: neurological clinical examination|OTHER: neuropsychological testing|OTHER: brain MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Knee Dislocation - Clinical Evaluation of the Use of Hinged External Fixator After Ligament Reconstruction
Status: UNKNOWN
Conditions: Knee Dislocation
Interventions: PROCEDURE: Surgery|DEVICE: Hinged External Fixator|DEVICE: Cast Immobilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Nab-paclitaxel in Pretreated Patients With Extensive Disease of Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ibrutinib With Rituximab in Adults With Waldenström's Macroglobulinemia
Status: COMPLETED
Conditions: Waldenström's Macroglobulinemia
Interventions: DRUG: Ibrutinib|DRUG: Placebo|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of Apixaban in Acute Coronary Syndrome (ACS) Japanese Patients
Status: TERMINATED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Apixaban|DRUG: Apixaban|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy, Safety, and Tolerability of E7070 in Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms|Metastases
Interventions: DRUG: E7070
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Resource Navigators to Support LTC and RH Staff During and Beyond COVID-19
Status: RECRUITING
Conditions: Wellness|Burnout, Caregiver|Burnout, Professional|COVID-19|Vaccine Refusal
Interventions: BEHAVIORAL: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Taste Acuity and Caloric Intake After Acute Morphine Administration
Status: COMPLETED
Conditions: Taste Sweet|Taste Salty|Feeding Behavior
Interventions: BEHAVIORAL: taste acuity assessment|BEHAVIORAL: Recorded meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
Status: RECRUITING
Conditions: Fracture|Bone Fracture|Dislocation|Fracture Multiple|Fractures, Closed|Fractures, Open
Interventions: OTHER: Cases reading|OTHER: Ground truthing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and Loneliness
Status: RECRUITING
Conditions: Emotion Regulation|Depressive Symptoms|Anxiety|Loneliness
Interventions: BEHAVIORAL: Tuned In
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Erector Spinae Block and Combined Deep and Superficial Serratus Anterior Plane Block
Status: COMPLETED
Conditions: Analgesia|Pain, Postoperative|Thoracic|Anesthesia
Interventions: PROCEDURE: erector spinae plane block|PROCEDURE: combined deep and superficial serratus anterior plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Long-term Effect of tDCS in Patients With Disorders of Consciousness
Status: COMPLETED
Conditions: Disorder of Consciousness
Interventions: DEVICE: transcranial direct current stimulation - active|DEVICE: transcranial direct current stimulation - sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment for Elderly Fit Newly Diagnosed Multiple Myeloma Patients Aged Between 65 and 80 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Newly Diagnosed Multiple Myeloma
Interventions: DRUG: Lenalidomide.|DRUG: Carfilzomib|DRUG: Bortezomib|DRUG: Daratumumab|DRUG: Dexamethasone|DRUG: Prednisone|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Atorvastatin on Androgens, Glucose Metabolism and Inflammation in Polycystic Ovary Syndrome (PCOS) Women
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation In Mandibular Molars Using Mixture Of ABB And Autogenous Particulate VS Sticky Bone
Status: UNKNOWN
Conditions: Alveolar Bone Loss|Bone Graft Failure|Alveolar Bone Resorption
Interventions: PROCEDURE: ABB And Autogenous Particulate|PROCEDURE: PRF, ABB & Autogenous Particulate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adhesive Strips in Dermatologic Surgery: Is Cosmetic Appearance Improved?
Status: COMPLETED
Conditions: Subjects Undergoing Surgical Procedure of the Skin
Interventions: PROCEDURE: Suture with Adhesive Stripping|PROCEDURE: Suture without Adhesive Stripping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Upadacitinib|DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Treatment Alone Versus Systemic Treatment Plus Radiotherapy in Oligometastatic Renal Cell Carcinoma
Status: RECRUITING
Conditions: Kidney Neoplasm
Interventions: RADIATION: SBRT(Stereotatic Body Radiation Therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label, Single Center, Single-arm, Phase 2 Study of Neoadjuvant Pembrolizumab in Combination With Carboplatin and Paclitaxel in Patients With Stage 1 cT1b-T1cN0M0 Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Stage 1 cT1b-T1cN0M0|Triple Negative Breast Cancer
Interventions: DRUG: Carboplatin|DRUG: Paclitaxel|DRUG: Pembrolizumab|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JUVEDERM® Ultra XC vs. Belotero Balance® for Perioral Lines
Status: COMPLETED
Conditions: Patients With Moderate to Severe Perioral Lines
Interventions: DEVICE: JUVEDERM® Ultra XC|DEVICE: Belotero Balance®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso
Status: COMPLETED
Conditions: Covid-19|Malaria
Interventions: DRUG: Artemether-lumefantrine (AL)|DRUG: Pyronaridine-artesunate (PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Racecadotril Versus Standard Treatment in Decreasing the Duration of Acute Diarrhoea in Children
Status: NOT_YET_RECRUITING
Conditions: Diarrhoea
Interventions: DRUG: Racecadotril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two GIC's in the Restoration of Posterior Class II Lesions in the Primary Dentition
Status: NOT_YET_RECRUITING
Conditions: Dental Caries
Interventions: DEVICE: DeltaFil|DEVICE: Riva Self Cure HV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Cardiac Output Monitoring in Obstetric Patients
Status: WITHDRAWN
Conditions: Complications; Cesarean Section|Anesthesia; Adverse Effect, Spinal and Epidural
Interventions: PROCEDURE: experimental|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Low-load Resistance Training With Blood Flow Restriction in Patients With Achilles Tendinopathy
Status: UNKNOWN
Conditions: Achilles Tendinopathy|Achilles Tendon Pain|Tendon Injuries
Interventions: OTHER: Low Load Training with Blood Flow Restriction|OTHER: High Load Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB
Status: UNKNOWN
Conditions: Tuberculosis, Pulmonary
Interventions: RADIATION: 11C-acetate ligand|RADIATION: FDG ligand
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: In Vivo Patient Preoperative Skin Prep Persistence
Status: COMPLETED
Conditions: Bacterial Recovery of Skin Flora Post-Product Application
Interventions: DRUG: 3M CHG/IPA Surgical Skin Preparation - Abdominal Region|OTHER: Normal Saline - Abdominal Region|DRUG: 3M CHG/IPA Surgical Skin Preparation - Inguinal Region|OTHER: Normal Saline - Inguinal Region
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Airway Management of Comatose Poisoned Emergency Patients
Status: COMPLETED
Conditions: Poisoning|Consciousness, Level Altered|Comatose
Interventions: PROCEDURE: Close monitoring|PROCEDURE: Endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Supplementation Compared With Hyaluronic Acid Infiltration in Rotator Cuff Tendinopathies
Status: RECRUITING
Conditions: Tendinitis of Shoulder|Hyaluronic Acid|Dietary Supplements|Shoulder Pain
Interventions: DIETARY_SUPPLEMENT: Collagen, Hyaluronic Acid, Vitamin C, and Manganese|DRUG: Intra-articular infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HemFitBit, an Observational Study of Physical Activity in People With Moderate and Severe Haemophilia A
Status: COMPLETED
Conditions: Hemophilia A Without Inhibitor
Interventions: DEVICE: PA measurement with Fitbit Charge 3|DEVICE: PA measurement with Fitbit and ActiGraph GT3X
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Post Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Iron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major
Interventions: DRUG: ICL670
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Bowel Preparation on Gut Microbiome in Patients Undergoing Endoscopic Colon Polypectomy
Status: COMPLETED
Conditions: Colon Polyp|Cathartic Colon
Interventions: DRUG: different types of laxatives (compounded polyethylene glycol electrolyte dispersions and compounded sodium pico-sulfate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: DDI HV (ATV - Merck)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: Atazanavir|DRUG: Atazanavir + Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Engaging Working Memory and Distress Tolerance to Aid Smoking Cessation
Status: TERMINATED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Wellness Education Control Condition|BEHAVIORAL: Mindfulness Training|BEHAVIORAL: Mindfulness Training Plus IE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Trial of Ipilimumab Versus Pemetrexed in Non-Squamous Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer - Non Small Cell
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spectral Analysis of Bowel Sounds in Preterm Babies of Less Than 32 Weeks of Amenorrhea (WA) as Predictive Factor of Enterocolitis
Status: RECRUITING
Conditions: Bowel Sounds|Spectral Analysis|Necrotizing Enterocolitis|Preterm Babies
Interventions: OTHER: Recording of the bowel sounds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Home-based Exercise Training in Patients With Pulmonary Arterial Hypertension: Effect on Skeletal Muscular Function and Metabolism
Status: UNKNOWN
Conditions: Pulmonary Arterial Hypertension|Exercise Training|Home-based Rehabilitation|Exercise Capacity|Muscle Metabolism|Muscle Function|Lipid Infiltration|Oxidative Metabolism
Interventions: BEHAVIORAL: Home-based rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eslicarbazepine Acetate as Therapy in Post-Herpetic Neuralgia
Status: TERMINATED
Conditions: Post Herpetic Neuralgia
Interventions: DRUG: Eslicarbazepine acetate (BIA 2-093)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT