pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study
Status: COMPLETED
Conditions: Atrial Fibrillation|Pericardial Effusion|Pleural Effusion|Hemothorax|Cardiac Tamponade
Interventions: DEVICE: Standard drainage|DEVICE: Active Tube Clearance drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Video-assisted Anal Fistula Treatment Versus Seton in the Management of High Peri Anal Fistula
Status: COMPLETED
Conditions: Post Operative Pain|Recurrence
Interventions: PROCEDURE: SETON|PROCEDURE: VAAFT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Mindfulness-based Stress Reduction Intervention for People With Chronic Pain Waiting for Health Services
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Mindfulness-based stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days
Status: COMPLETED
Conditions: Skin Reaction to Mechanical, Thermal and Radiation Stimuli|Skin Sensitisation
Interventions: DEVICE: Sponsor incisional negative pressure wound therapy device and dressing|DEVICE: Standard of Care incisional negative pressure wound therapy system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Immune Response to Preventive HIV Immunization With Adenovirus Serotype 5 or 35 Vector
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA Vaccine|BIOLOGICAL: DNA Vaccine placebo|BIOLOGICAL: rAd35|BIOLOGICAL: rAd35 placebo|BIOLOGICAL: rAd5|BIOLOGICAL: rAd5 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Increased Re-eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Triple Therapy
Status: UNKNOWN
Conditions: Bacterial Infection Due to Helicobacter Pylori (H. Pylori)
Interventions: DRUG: 10RAC+acetylcystein|DRUG: 10RAC+metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mindfulness Meditation and Loving-kindness and Compassion Meditation on Psychological Distress
Status: COMPLETED
Conditions: MM Group|LKCM Group|Waitlist Group
Interventions: OTHER: mindfulness meditation intervention and loving-kindness and compassion meditation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Non-invasive Vagal Neurostimulation (nVNS) for Traumatic Brain Injury (TBI)-Induced Acute Respiratory Distress
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)|Traumatic Brain Injury
Interventions: DEVICE: nVNS|OTHER: SOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quetiapine for Bipolar Disorder and Alcohol Dependence
Status: COMPLETED
Conditions: Bipolar Disorder|Alcohol Dependence
Interventions: DRUG: Placebo|DRUG: Quetiapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate IMG-004 in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: SAD IMG-004 30mg|DRUG: SAD IMG-004 100mg|DRUG: SAD IMG-004 200mg|DRUG: SAD IMG-004 400mg|DRUG: SAD IMG-004 600mg|DRUG: SAD Placebo 30mg|DRUG: SAD Placebo 100mg|DRUG: SAD Placebo 200mg|DRUG: SAD Placebo 400mg|DRUG: SAD Placebo 600mg|DRUG: MAD IMG-004 50mg|DRUG: MAD Placebo 50mg|DRUG: MAD IMG-004 150mg|DRUG: MAD Placebo 150mg|DRUG: MAD IMG-004 300mg|DRUG: MAD Placebo 300mg|DRUG: FE IMG-004 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
Status: UNKNOWN
Conditions: Diagnoses Disease|Glioma of Brain
Interventions: DIAGNOSTIC_TEST: APT MR Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes
Status: RECRUITING
Conditions: Newly Diagnosed Type 1 Diabetes Mellitus
Interventions: DRUG: UCMSCs|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Colonic Tube to Improve Bowel Function in Spinal Cord Injury
Status: COMPLETED
Conditions: Constipation|Fecal Incontinence|Spinal Cord Injury
Interventions: DEVICE: Percutaneous endoscopic colostomy (PEC) tube
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BMI Effect on the Response to Ovulation Induction in Letrozole vs Clomid
Status: UNKNOWN
Conditions: Subfertility
Interventions: DRUG: Clomiphene Citrate 50mg|DRUG: Letrozole 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Gelatine Solutions
Status: COMPLETED
Conditions: Hypovolemia
Interventions: DRUG: Gelofusine balanced|DRUG: Gelofusine 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NGR-hTNF in Combination With Standard Chemotherapy to Treat Patients With Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: NGR-hTNF|DRUG: Cisplatin|DRUG: Gemcitabine|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetic Profile of of GSK2118436 in Japanese Subjects With BRAF Mutation Positive Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: GSK2118436
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trilostane for Androgen-Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer|Prostate Adenocarcinoma
Interventions: DRUG: Trilostane|DRUG: Hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Samuraciclib and Elacestrant in Participants With Metastatic or Locally Advanced HR+/HER2-negative Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Locally Advanced Breast Cancer|Breast Cancer
Interventions: DRUG: Samuraciclib|DRUG: Elacestrant Dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Observer-blind, Placebo-controlled, Randomized Study to Evaluate the Immunogenicity and Safety of MenACWY in Adolescents and Adults in Korea
Status: COMPLETED
Conditions: Meningococcal Disease|Meningococcal Meningitis
Interventions: BIOLOGICAL: Novartis MenACWY-CRM|BIOLOGICAL: Saline Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: LaPAroscopic Low pRessure cOlorectal Surgery
Status: COMPLETED
Conditions: Malignant or Benign Pathology
Interventions: DEVICE: Airseal®|DEVICE: Standard Insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Telemedicine During COVID-19: Non-clinical Validation
Status: UNKNOWN
Conditions: Telemedicine|Surgery, Plastic
Interventions: OTHER: 3D Telemedicine|OTHER: 2D Telemedicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Supervised Exercise in Improving Physical Fitness Before Surgery in Patients With Resectable Bone Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Malignant Bone Neoplasm
Interventions: DEVICE: Activity Monitor|BEHAVIORAL: Exercise Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Lapaquistat Acetate Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Lapaquistat acetate|DRUG: Lapaquistat acetate and ezetimibe|DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord
Status: WITHDRAWN
Conditions: Central Nervous System Sarcoma|Ependymoma|Glioma|Malignant Intracranial Germ Cell Tumor|Medulloblastoma|Pineoblastoma|Primary Central Nervous System Neoplasm
Interventions: OTHER: Placebo Administration|OTHER: Questionnaire Administration|DRUG: Wound Dressing Material
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Assess the Safety and Feasibility of Adoptive Cell Therapy With Autologous EBV-specific Cytotoxic T Lymphocytes (CTL) in Patients With a First Clinical Episode Highly Suggestive of Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: Cellular therapy with EBV specific autologous CTL infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mentor Siltex® Contour Profile Gel Mammary Prosthesis Clinical Trial
Status: COMPLETED
Conditions: Breast Augmentation|Breast Reconstruction|Breast Revision
Interventions: DEVICE: Mentor Siltex® Contour Profile Gel Mammary Prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Levofloxacin for the Treatment of MDR-TB
Status: COMPLETED
Conditions: Tuberculosis, Multidrug-Resistant
Interventions: DRUG: Levofloxacin|DRUG: Optimized background regimen (OBR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adenoidectomy for Otitis Media in 2-3 Year Old Children
Status: TERMINATED
Conditions: Otitis Media With Effusion
Interventions: PROCEDURE: bilateral myringotomy|PROCEDURE: bilateral myringotomy and tubes|PROCEDURE: adenoidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Does ESP Block Reduce Pain and Opiates Consumption After Surgery
Status: UNKNOWN
Conditions: Post Operative Pain|Regional Anesthesia Morbidity|Opioid-Related Disorders|Chronic Pain
Interventions: PROCEDURE: erector spinea plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: TMC435 HPC1004 - Phase I Study Investigating the Pharmacokinetics of TMC435 in Healthy Chinese Volunteers
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: TMC435|DRUG: TMC435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population
Status: COMPLETED
Conditions: Cirrhosis Renal
Interventions: DRUG: Iohexol Inj 300 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of a 3-month Treatment Course of Ulipristal Acetate for the Treatment of Abnormal Uterine Bleeding Associated With Leiomyomas
Status: COMPLETED
Conditions: Leiomyoma|Uterine Hemorrhage
Interventions: DRUG: Ulipristal acetate (UPA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telenutrition Weight Loss Study for Men
Status: COMPLETED
Conditions: Obesity|Weight Loss|Men
Interventions: BEHAVIORAL: Registered Dietitian Nutritionist (RDN) Support|BEHAVIORAL: Diet-related educational materials|BEHAVIORAL: Self-monitoring tools
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Adjunctive TBO-309 in Reperfusion for Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: TBO-309
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TempTouch IR Thermometry & Diabetic Patient Self-Care
Status: COMPLETED
Conditions: Diabetic Polyneuropathy|Diabetic Foot Ulcer|Diabetes|Foot Infection
Interventions: DEVICE: TempTouch®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin glulisine|DRUG: Insulin aspart|DRUG: Regular human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2216684 in Healthy Participants Receiving Albuterol or Propanolol
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: LY2216684|DRUG: albuterol|DRUG: propranolol|DRUG: placebo for LY2216684|DRUG: placebo for albuterol|DRUG: placebo for propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Rabeprazole Sodium Administered With Different Dosing Vehicles in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rabeprazole sodium: Treatment E|DRUG: Rabeprazole sodium: Treatment C|DRUG: Rabeprazole sodium: Treatment D|DRUG: Rabeprazole sodium: Treatment A|DRUG: Rabeprazole sodium: Treatment B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy of DLBS1033 in Patients With Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: DRUG: DLBS1033|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Sequential Single and Multiple Ascending Dose (SAD/MAD) Study of SK10 Powders in Healthy Adult Subjects
Status: COMPLETED
Conditions: Chemotherapy-induced Diarrhea
Interventions: DRUG: SK10|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics in Healthy Volunteers
Status: UNKNOWN
Conditions: Cardiovascular Disease
Interventions: DRUG: CKD-330 Tab. and D086 Tab.|DRUG: CKD-333 Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Monitoring of Fetal Risk of Inflammation in Preterm Premature Rupture of Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membranes|Fetal Inflammatory Response Syndrome|Early Onset Neonatal Sepsis|Infection of Amniotic Cavity
Interventions: OTHER: single arm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pregabalin Versus Placebo as an Add on for Complex Regional Pain Syndrome (CPRS) of the Upper Limb Managed by Stellate Ganglion Block (The PREGA Study)
Status: TERMINATED
Conditions: Complex Regional Pain Syndromes
Interventions: DRUG: Pregabalin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Omentectomy on the Hyperglycemia and the Resistance to the Insulin in Patients With Morbid Obesity
Status: COMPLETED
Conditions: Obesity|Diabetes Mellitus Type 2
Interventions: PROCEDURE: omentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prevention of Treatment Induced Neuropathy in Multiple Myeloma
Status: COMPLETED
Conditions: Myeloma
Interventions: OTHER: Placebo|DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Recovery After Laparoscopic Hysterectomy With Deep Neuromuscular Blockade and Low Intra-abdominal Pressure
Status: COMPLETED
Conditions: Neuromuscular Blockade|Pain|Laparoscopy
Interventions: DRUG: Rocuronium|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: GENETIC: Intranodal immunization with a recombinant vaccinia virus expressing 5 transgenes|BIOLOGICAL: Intranodal booster immunizations with synthetic melanoma associated epitopes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HIgh-flow Therapy in Long-term Oxygen Therapy
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease Severe|Interstitial Lung Disease|Chronic Respiratory Failure With Hypoxia
Interventions: DEVICE: Added high-flow oxygen therapy|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Athlete Whey Protein Sensitivity: Prevalence and Performance
Status: COMPLETED
Conditions: Food Intolerance
Interventions: DIETARY_SUPPLEMENT: Whey Protein Concentrate|DIETARY_SUPPLEMENT: Pea Protein Isolate, Rice Protein Concentrate, Hemp Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A JNJ-56021927 (ARN-509; Apalutamide) QT/QTc Study
Status: COMPLETED
Conditions: Castration-Resistant Prostate Cancer
Interventions: DRUG: Apalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Linguistically-Tailored Mobile Intervention for the Improvement of Follow Up for Abnormal Pap Test Results
Status: COMPLETED
Conditions: Cervical Carcinoma
Interventions: OTHER: Health Promotion and Education|OTHER: Survey Administration|OTHER: Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Midwest TXTXT Scale up of an Evidence-Based Intervention to Promote HIV Medication Adherence
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: BEHAVIORAL: Treatment Text (TXTXT)|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phytoestrogens as an Alternative to Estradiol in Ovulation Induction in PCOS
Status: COMPLETED
Conditions: Polycystic Ovaries
Interventions: DRUG: phytoestrogen|DRUG: estradiol valerate|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine Safety and Dosage of OPTISON in Pediatric Participants
Status: COMPLETED
Conditions: Transthoracic Echocardiography|Suspected or Known Structural or Functional Cardiac Abnormality
Interventions: DRUG: Optison
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|PROCEDURE: Biopsy|DRUG: Enasidenib|DRUG: Ivosidenib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug-drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lanabecestat|DRUG: Dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma, Adult|Non-Hodgkin Lymphoma, Refractory|Non-Hodgkin Lymphoma, Relapsed|Non Hodgkin Lymphoma|Hodgkin Lymphoma|Hodgkin Lymphoma, Adult|Hodgkin's Lymphoma, Relapsed, Adult
Interventions: DRUG: MT-601
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LBNP Tolerance With Skin Warming After Exercise Cold Stress
Status: RECRUITING
Conditions: Blood Pressure|Blood Loss
Interventions: OTHER: Skin Surface Rewarming|OTHER: Skin Surface Warming|OTHER: Skin Surface Heating|OTHER: Skin Surface Cooling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study
Status: COMPLETED
Conditions: Non Celiac Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: High dose Gluten|DIETARY_SUPPLEMENT: Low dose Gluten|DIETARY_SUPPLEMENT: Lactose free placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Anti-inflammatory Therapy to Improve Outcomes After TPIAT
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatitis, Chronic; Diabetes; Transplant
Interventions: DRUG: etanercept|DRUG: Alpha 1-Antitrypsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Volume Plasmapheresis for Refractory Hepatic Encephalopathy in Liver Intensive Care Unit.
Status: WITHDRAWN
Conditions: Refractory Hepatic Encephalopathy
Interventions: DRUG: Lactulose|DRUG: Rifaximin|BIOLOGICAL: Plasmapheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Taspoglutide Versus Pioglitazone in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: pioglitazone|DRUG: taspoglutide|DRUG: taspoglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: UGIST: Ultrasound Guided Internal Jugular Short-Term Central Venous Catheters Tunneling
Status: UNKNOWN
Conditions: Infection|Bacteremia
Interventions: PROCEDURE: To tunnel|PROCEDURE: Standard (not to tunnel)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Photodynamic Therapy With Annatto and Led for the Treatment of Halitosis in Mouth-Breathing Children
Status: COMPLETED
Conditions: Halitosis
Interventions: PROCEDURE: Teeth Brushing|PROCEDURE: Dental Flossing|PROCEDURE: Tongue Scraping|RADIATION: Antimicrobial Photodynamic Therapy (aPDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Platelet-Rich Plasma (PRP) Centrifugation Methods on Thrombocyte Concentration and Clinical Improvement of Androgenetic Alopecia
Status: RECRUITING
Conditions: Alopecia, Androgenetic
Interventions: PROCEDURE: Platelet-Rich Plasma Injections (PRP) on the Scalp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Manidipine Versus Amlodipine in Patients With Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Manidipine 20mg|DRUG: Amlodipine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: First-in-man Study of Single Ascending Dose of a New Drug for Neurological Disorders
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: AC-083|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: Procalcitonin-guided decision making
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Permanent Atrial Fibrillation
Status: RECRUITING
Conditions: Recurrent Atrial Fibrillation|Persistent Atrial Fibrillation
Interventions: PROCEDURE: Atrioventricular junction ablation in patients with cardiac resynchronization therapy (CRT)|DRUG: Optimal medication treatment in patients with cardiac resynchronization therapy (CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Stabilization Exercises for Low Back Pain in Adolescents With Idiopathic Scoliosis
Status: COMPLETED
Conditions: Adolescent Idiopathic Scoliosis|Low Back Pain
Interventions: OTHER: supervised spinal stabilization exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on the Use of Methoxyflurane (Penthrox®) for Pain Control in the Emergency Department
Status: COMPLETED
Conditions: Acute Traumatic Pain
Interventions: DRUG: Methoxyflurane|DRUG: Ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Memantine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cereset Research In Healthcare Workers During COVID-19
Status: COMPLETED
Conditions: Health Personnel|Stress|Anxiety|Insomnia|Hyperarousal|Corona Virus Infection|Covid19
Interventions: DEVICE: Cereset Research
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PEP Breathing Versus Incentive Spirometry on Dyspnea and Sputum Profile in Bronchiolectasis Patients
Status: COMPLETED
Conditions: Bronchiolectasis
Interventions: OTHER: PEP (Positive Expiratory Pressure)|OTHER: IS (Incentive spirometry)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients
Status: COMPLETED
Conditions: Uveitis|Anterior Uveitis|Intermediate Uveitis|Posterior Uveitis|Scleritis|Clinically Significant Macular Edema
Interventions: DRUG: H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Video Images About Decisions for Ethical Outcomes in the Emergency Department (VIDEO-ED)
Status: RECRUITING
Conditions: Emergencies
Interventions: BEHAVIORAL: video decision aid|BEHAVIORAL: control arm ACP information sheet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of Dual-targeted Therapy With Upadacitinib and Ustekinumab Versus Intensified Ustekinumab Therapy in Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Crohn Disease
Interventions: DRUG: Ustekinumab and Upadacitinib|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: FET-PET Directed Simultaneous In-field Boost for Primary GBM
Status: COMPLETED
Conditions: Glioblastoma Multiforme
Interventions: RADIATION: Moderately Hypofractionated Radiotherapy using Simultaneous In-Field Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Treatment Perspectives in Eating Disorders: the Efficacy of Non-invasive Brain-directed Treatment
Status: UNKNOWN
Conditions: Eating Disorders|Binge Eating Disorder|Anorexia Nervosa
Interventions: DEVICE: AN Active tDCS|DEVICE: AN Sham tDCS|DEVICE: BED Active tDCS|DEVICE: BED Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-line Anlotinib Combined With Penpulimab for Advanced Pheochromocytoma: A Single-arm, Multicenter, Prospective Phase II Study
Status: RECRUITING
Conditions: Pheochromocytoma
Interventions: DRUG: Anlotinib and Penpulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predict Sepsis; the Predictive Value of Bedside Measures in the Ambulance
Status: COMPLETED
Conditions: Sepsis|Sepsis Syndrome|Sepsis, Severe
Interventions: DIAGNOSTIC_TEST: Blood test: Glukos, SuPAR, Laktat and HBP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Administration of T Lymphocytes for Prevention of Relapse of Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Hodgkin Disease|Lymphoma|Lymphoma, Non-Hodgkin|Immune System Diseases|Immunoproliferative Disorders|Lymphatic Diseases|Lymphoproliferative Disorders|Neoplasms|Neoplasms by Histologic Type
Interventions: DRUG: ATLCAR.CD30 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracic Surgery
Status: UNKNOWN
Conditions: Video-assisted Thoracoscopic Surgery
Interventions: PROCEDURE: Cervical Vagal Blockade|PROCEDURE: Without Blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CSD170302: Study to Assess Nicotine Uptake in Smokers From Electronic Cigarettes
Status: COMPLETED
Conditions: Smoking
Interventions: OTHER: FT21018|OTHER: FT21033|OTHER: FT21034|OTHER: FT21035
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase II Study of SCH66336, A Farnesyltransferase Inhibitor in Chronic Myelogenous Leukemia (CML)
Status: COMPLETED
Conditions: Myelogenous Leukemia, Chronic
Interventions: DRUG: SCH66336
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Carboplatin Followed by Cisplatin and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: DRUG: carboplatin|DRUG: cisplatin|DRUG: paclitaxel|PROCEDURE: neoadjuvant therapy|RADIATION: brachytherapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Thumb Osteoarthritis
Interventions: DEVICE: PEMF device|DEVICE: Sham PEMF device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Carboplatin With or Without ZD4054 in Patients With Metastatic Breast Cancer
Status: WITHDRAWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Placebo|DRUG: ZD4054
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ERCP in the Diagnosis and Treatment of Idiopathic Recurrent Acute Pancreatitis
Status: RECRUITING
Conditions: Recurrent Acute Pancreatitis
Interventions: PROCEDURE: ERCP|COMBINATION_PRODUCT: Health education and conservative management of clinical routines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Dysport RU and Glabellar Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: Botulinum toxin type A|BIOLOGICAL: Botulinum toxin type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation of a Leucine-enriched Protein Blend
Status: COMPLETED
Conditions: Dietary Modification|Diet Habit
Interventions: DIETARY_SUPPLEMENT: Leucine-enriched protein|BEHAVIORAL: Habitual diet only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of AVE5026 in the Prevention of Venous Thromboembolism in Acutely Ill Medical Patients With Restricted Mobility
Status: TERMINATED
Conditions: Venous Thromboembolism
Interventions: DRUG: Semuloparin sodium|DRUG: Enoxaparin sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: QuikClot® Radial® Pad Versus TR Band® After Transradial Artery Access (TRA)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: Quikclot Radial Pad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Placebo|DRUG: Dasatinib|DRUG: Docetaxel|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Interactive Computer Game, Called Duck Duck Punch, for Stroke Rehabilitation at Home and in a Rehabilitation Clinic
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: an interactive computer game|BEHAVIORAL: standard activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Abiraterone Acetate in Patients With Advanced Prostate Cancer
Status: APPROVED_FOR_MARKETING
Conditions: Prostate Neoplasms|Genital Neoplasms, Male|Urogenital Neoplasms|Genital Diseases, Male
Interventions: DRUG: Abiraterone Acetate|DRUG: Prednisone\Prednisolone
Study Type: EXPANDED_ACCESS
Clinical trial: Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) as Maintenance Treatment in Adults With Schizophrenia
Status: COMPLETED
Conditions: Acute Schizophrenia
Interventions: DRUG: Brexpiprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation
Status: RECRUITING
Conditions: Acute Pancreatitis|Recurrent Acute Pancreatitis
Interventions: BEHAVIORAL: Standard intervention only|BEHAVIORAL: Standard intervention plus repeated intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial of Docetaxel and Oxaliplatin in Patients With Recurrent or Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Recurrent Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: docetaxel/ oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma
Status: COMPLETED
Conditions: Contiguous Stage II Adult Diffuse Large Cell Lymphoma|Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma|Stage I Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma
Interventions: DRUG: Carfilzomib|BIOLOGICAL: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin hydrochloride|DRUG: Vincristine sulfate|DRUG: Prednisone|DRUG: Pegfilgrastim|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship of Haptoglobin Phenotype to Vascular Function and Response to Vitamin E Supplementation in Patients With Diabetes Mellitus Type 2: The EVAS Trial
Status: UNKNOWN
Conditions: Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: Vitamin E|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Does 3 Months Therapy With Vitamin D + Peg + Ribavirin Improve Sustained Virologic Response (SVR) in Genotype 2, 3 Chronic Hepatitis C Patients?
Status: UNKNOWN
Conditions: Chronic Hepatitis C
Interventions: DRUG: Peg + Vitamin D + Ribavirin|DRUG: Peg + Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Trial to Compare the Safety and Neutralizing Activity of CL184 in Combination With Rabies Vaccine vs. HRIG or Placebo in Combination With Rabies Vaccine in Healthy Adult Subjects
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: CL184|BIOLOGICAL: HRIG|BIOLOGICAL: Placebo matching CL184
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessing the Utility of Tissue Dielectric Constant (TDC) Measurements to Differentiate Breast Cancer From Healthy Breasts
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: TDC differential value
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Synera Venipuncture Pain
Status: COMPLETED
Conditions: Pain|Phlebotomy|Palliative Care
Interventions: DRUG: Synera (lidocaine 70mg/tetracaine 70mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SAR292833 Administration for 4 Weeks in Patients With Chronic Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Neuropathic Pain
Interventions: DRUG: SAR292833|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial
Status: RECRUITING
Conditions: Cerebral Palsy Infantile|Disabilities Multiple|Pain
Interventions: BEHAVIORAL: PediQUEST ResPOND
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lidocaine Before Esophageal Manometry and Ambulatory pH Monitoring
Status: COMPLETED
Conditions: Pain, Acute
Interventions: DRUG: Saline spray|DRUG: Lidocaine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Status: COMPLETED
Conditions: Erector Spinae Plane Block|Pain Control|Post-Operative Pain, Chronic
Interventions: DRUG: Intravenous Administration of Lidocaine Post Cardiac Surgery|DRUG: Administration of Lidocaine Post Cardiac Surgery via ESP Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis|NAFLD|Metabolic Syndrome
Interventions: DIAGNOSTIC_TEST: LiverMultiScan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Histological and Imaging Assessment of the Structural Characteristics of the Femoro-popliteal Arterial Segment
Status: UNKNOWN
Conditions: Chronic Limb Ischemia
Interventions: PROCEDURE: Explantation of the femoro-popliteal arterial segment from the amputed limb
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiviral Effect, Safety, and Pharmacokinetics of BI201335 +PegIFN/RBV in HCV-GT1 (SILEN-C1&2)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: BI 201335 NA 240 mg QD / LI|DRUG: PegIFN/RBV|DRUG: BI 201335 NA 120mg QD / LI|DRUG: PegIFN/RBV|DRUG: BI 201335 NA 240 mg QD|DRUG: PegIFN/RBV|DRUG: BI 201335 NA 240 mg QD|DRUG: PegIFN/RBV|DRUG: BI 201335 NA 240 mg BID|DRUG: PegIFN/RBV|DRUG: PegIFN/RBV|DRUG: BI 201335 NA 240 mg QD|DRUG: PegIFN/RBV|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of GBT009 for Treatment of Incisional Wounds Following Breast Reconstruction Surgery
Status: COMPLETED
Conditions: Scar Formation
Interventions: BIOLOGICAL: GBT009|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fed Bioequivalence Study of CBZ Formulations
Status: COMPLETED
Conditions: Bio-equivalence Study|Fed Conditions
Interventions: DRUG: Auration CR Tablets 400 Single Dose-Tegretol CR 400 Single Dose|DRUG: Tegretol CR 400 Single Dose-Auration CR 400 Single Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: Homeopathic Medication and Nutritional Oriented Diet to Treat Overweight Pregnant Women With Mental Disorder
Status: COMPLETED
Conditions: Overweight|Pregnancy|Mental Disorder
Interventions: DRUG: Sulph, Puls, Lyc, Lack t, Con, Sep, Nux v, Calc c, Phos|DRUG: Homeopathy and Nutritional oriented diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT