pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of a Wearable Hip Assist Robot on Cardiopulmonary Metabolic Efficiency During Stair Ascent in Elderly Adults
Status: COMPLETED
Conditions: Gait, Unsteady|Health Behavior
Interventions: DEVICE: Wearable hip assist robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9
Status: COMPLETED
Conditions: Cataracts|Astigmatism
Interventions: DEVICE: SN6AT6 Intraocular Lens|DEVICE: SN6AT7 Intraocular Lens|DEVICE: SN6AT8 Intraocular Lens|DEVICE: SN6AT9 Intraocular Lens|DEVICE: SN60WF Intraocular Lens
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabis Use on Sedation for Oral Surgery Procedures
Status: RECRUITING
Conditions: Cannabis Use
Interventions: DRUG: Sedation with Midazolam, Fentanyl, and Propofol|PROCEDURE: Extraction of teeth
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Decision Support Tool for Gonadotrophin Dose Selection in ART.
Status: COMPLETED
Conditions: IVF
Interventions: DEVICE: OPTIVF dosage|DEVICE: traditional drug treament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of High-dose Influenza Vaccine Efficacy by Repeated Dosing IN Gammopathy Patients
Status: COMPLETED
Conditions: Influenza|Multiple Myeloma|Waldenstrom's Macroglobulinemia|Plasma Cell Disorders|MGUS
Interventions: BIOLOGICAL: Fluzone High Dose Vaccine|BIOLOGICAL: Standard of care/Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Medication Review in High-risk Emergency Department Patients
Status: COMPLETED
Conditions: Adverse Drug Events|Adverse Drug Reactions|Medication-related Problems
Interventions: OTHER: Pharmacist-led medication review
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
Status: RECRUITING
Conditions: Hypertension|Stroke|TIA|Vascular Diseases
Interventions: BEHAVIORAL: Use of Omron Home Blood Pressure Cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RCT of an Internet-based CBT Program for Sexuality and Intimacy Problems in Women Treated for Breast Cancer
Status: COMPLETED
Conditions: Sexual Dysfunction|Intimacy Problems|Breast Cancer Survivors
Interventions: BEHAVIORAL: Internet-based cognitive behavioral therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Lens A (lehfilcon A lens)|DEVICE: Lens B (comfilcon A lens)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Frontal Electroencephalography of Neonatal Patients Under Sedation With Opioids and General Anesthesia With Propofol.
Status: COMPLETED
Conditions: Anesthesia|Surgery|Neonate|Depth of Anesthesia
Interventions: DRUG: Propofol Group 1|DRUG: Propofol Group 2|DRUG: Propofol Group 3|DRUG: Propofol Group 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Wear of Vita Ambria Only Restoration Compared With IPS Emax Onlay Restoration
Status: RECRUITING
Conditions: Carious Tooth|Dental Wear
Interventions: OTHER: Vita Ambria|OTHER: IPs emax onaly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zanubrutinib Combined With Standard Chemotherapy in the Treatment for Patients With Diffuse Large B Cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B Cell Lymphoma|CD79A Gene Mutation|CD79B Gene Mutation
Interventions: DRUG: Rituximab|DRUG: Zanubrutinib|DRUG: Cyclophosphamide|DRUG: Epirubicin|DRUG: Vincristine|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY2951742 in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: LY2951742|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Status: COMPLETED
Conditions: Long QT Syndrome|Cardiac Repolarization
Interventions: DRUG: Placebo|DRUG: Propranolol LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of AJU-C52 in Essential Hypertension Patients
Status: RECRUITING
Conditions: Essential Hypertension
Interventions: DRUG: AJU-C52L, AJU-C52|DRUG: C52R1L, C52R1M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phosphorylcholine PC-mAb Effects in Subjects With Elevated Lipoprotein a
Status: TERMINATED
Conditions: Arterial Inflammation|Cardiovascular Diseases
Interventions: DRUG: PC-mAb|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Gastric Cancer
Status: COMPLETED
Conditions: Locally Advanced Malignant Neoplasm|Gastric Cancer
Interventions: DRUG: Hyperthermic Intraperitoneal Chemotherapy (HIPEC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NovaTears® + Omega-3 (0.2%) Eye Drops on Signs and Symptoms of Dry Eye
Status: COMPLETED
Conditions: Evaporative Dry Eye Disease
Interventions: DEVICE: NovaTears® + Omega-3 (Perfluorohexyloctane with 0.2% w/w Omega-3 fatty acid ethyl esters)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Bedside Ultrasound in Emergency Department Patients With Concern for Pulmonary Embolism to Reduce CT Imaging
Status: UNKNOWN
Conditions: Pulmonary Embolism|Deep Vein Thrombosis Leg|Ultrasound Imaging
Interventions: DIAGNOSTIC_TEST: Lower extremity Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Serum 25(OH) Vitamin D and Total Serum Immunoglobulin E Levels in Patients With Pityriasis Alba
Status: ACTIVE_NOT_RECRUITING
Conditions: Pityriasis Alba
Interventions: DIAGNOSTIC_TEST: Detection of Plasma levels of 25(OH) vitamin D by ELISA technique|DIAGNOSTIC_TEST: Detection of Total serum immunoglobulin E by ELISA technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Product Effectiveness of the Intervention for Patients With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Product Use Issue|Sports Physical Therapy
Interventions: DEVICE: sensor and wearable device "Graded Exercise"|OTHER: exercise|OTHER: Educational Manual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Auricular Acupuncture for Analgesia During Total Hip Arthroplasty
Status: COMPLETED
Conditions: Acute Pain|Total Hip Arthroplasty
Interventions: PROCEDURE: Auricular acupuncture (procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Carcinoid Tumors|Neuroblastoma|Medulloblastoma
Interventions: DRUG: 68Ga-DOTATOC PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase 3 Study Evaluating Efficacy and Safety of DSC127 Compared With Vehicle and With Standard-of-care in Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Diabetic Foot Ulcers
Interventions: DRUG: DSC127|DRUG: placebo vehicle gel|DRUG: Standard of Care gel, Aquasite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sleep Apnea Treatment on Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes|Sleep Apnea Syndrome
Interventions: DEVICE: continuous positive airway pressure|DEVICE: Sham-continuous positive airway pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inpatient Smoking Cessation Pilot Program
Status: WITHDRAWN
Conditions: Tobacco Use Cessation
Interventions: DRUG: Nicotine lozenge|DRUG: Nicotine gum|DRUG: Nicotine patch|OTHER: Maryland Quitline|OTHER: John Hopkins Tobacco Treatment Clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LY3209590
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Heating Precondition of Epidural Catheter Decrease the Incidence of Injury to Blood Vessel During Epidural Catheter Placement
Status: UNKNOWN
Conditions: Epidural Anesthesia
Interventions: OTHER: heating precondition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS).
Status: COMPLETED
Conditions: Nfuence of Vasoactive Medication on Spinal Oxygenation
Interventions: DRUG: Phenylephrine|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Gastric Emptying Ultrasound Research Study
Status: COMPLETED
Conditions: Gastric Emptying
Interventions: PROCEDURE: Ultrasound|OTHER: 2% milk|OTHER: apple juice|OTHER: ensure clear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Daratumumab Combined With Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting With Extramedullary Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Extramedullary Plasmacytoma
Interventions: DRUG: Daratumumab|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Sleep, Liver Evaluation and Effective Pressure Study
Status: COMPLETED
Conditions: Non Alcoholic Fatty Liver Disease|Obstructive Sleep Apnea
Interventions: DEVICE: CPAP (ResMed S9 autoset CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Psychotherapy Intervention in Depressed Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Depression|Coronary Artery Disease
Interventions: BEHAVIORAL: Psychotherapy|BEHAVIORAL: Information session|OTHER: Usual cardiological care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index
Status: COMPLETED
Conditions: Gingival Inflammation
Interventions: DEVICE: Toothpaste Tablet|DEVICE: Conventional Toothpaste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Classic and Virtual Inhaler Training Methods in COPD Patients
Status: COMPLETED
Conditions: COPD|Inhaler Training|Face-to-face Training|Video-mediated Virtual Training
Interventions: OTHER: Treatment training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Single Ascending Dose Trial in Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: AMG 876
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of FZ-AD005 in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor, SCLC(Small Cell Lung Cancer) or LCNEC (Large Cell Neuroendocrine Carcinoma)
Interventions: DRUG: FZ-AD005
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dopaminergic Medication on Recovery of Aphasia
Status: COMPLETED
Conditions: Aphasia
Interventions: DRUG: levodopa and benserazide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study Between YHP1906 Tab. 5 mg and YHR1902 Tab. 5 mg
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: YHP1906|DRUG: YHR1902
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Conversion Study of Epoetin Alfa in Subjects With the Anemia of Chronic Kidney Disease.
Status: TERMINATED
Conditions: Anemia|Chronic Renal Insufficiency
Interventions: DRUG: Epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continuous Preperitoneal Infusion of Local Anesthetic (CPA) Versus Epidural Infusion of Local Anesthetic (EA) in Fast-Track Open Colorectal Surgery
Status: UNKNOWN
Conditions: Open Colorectal Surgery|Early Rehabilitation After Surgery
Interventions: OTHER: Multilobed catheter (group CPA)|OTHER: Multilobed catheter (group EA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Subjective Comfort With Multipurpose and Hydrogen Peroxide Lens Care Solutions in Soft Contact Lens Wearers
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: OPTI-FREE RepleniSH multipurpose disinfecting solution|DEVICE: Clear Care contact lens care system|DEVICE: Contact lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Letters Promoting Colorectal Cancer Testing
Status: COMPLETED
Conditions: Cancer Colorectal
Interventions: BEHAVIORAL: Letter|BEHAVIORAL: Loss Frame and Fear Appeals|BEHAVIORAL: Transparency|BEHAVIORAL: Default Effect and Presentation of Alternatives|BEHAVIORAL: Enhanced Fear Appeals and Decoy Effect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Camrelizumab Combined With Chemotherapy and Apatinib for Extrapulmonary Neuroendocrine Carcinomas
Status: NOT_YET_RECRUITING
Conditions: Advanced or Metastatic EP-NEC
Interventions: DRUG: Camrelizumab|DRUG: Etoposide|DRUG: Carboplatin|DRUG: Cisplatin|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Efficacy of Drug Sensitive Neoadjuvant Chemotherapy Based on Organoid Versus Traditional Neoadjuvant Chemotherapy in Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Neoadjuvant Therapy
Interventions: DRUG: standard long-term therapy|DRUG: FOLFOX and standard long-term radiotherapy|DRUG: FOLFIRI and standard long-term radiotherapy|DRUG: 5-FU and standard long-term radiotherapy|DRUG: 5-FU and pembrolizumab and standard long-term radiotherapy|DRUG: Other individualized treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Aztreonam for Inhalation Solution (AZLI) in Patients With Cystic Fibrosis and Chronic Burkholderia Species Infection
Status: COMPLETED
Conditions: Cystic Fibrosis|Burkholderia Infections
Interventions: DRUG: AZLI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability Comparison Between Differin® Cream 0.1% Versus Differin® Lotion 0.1% in Subjects With Healthy Skin
Status: COMPLETED
Conditions: Skin Manifestations
Interventions: DRUG: adapalene cream 0.1%|DRUG: adapalene lotion 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Lifting Light or Heavy Weights on Muscle Growth and Strength in Trained Young Men
Status: COMPLETED
Conditions: Skeletal Muscle Hypertrophy|Muscle Weakness
Interventions: BEHAVIORAL: 30% 1RM|BEHAVIORAL: 80% 1RM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists
Status: ACTIVE_NOT_RECRUITING
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: RNR inhibitor COH29|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema
Status: COMPLETED
Conditions: Retinitis Pigmentosa|Cystoid Macular Edema
Interventions: DRUG: rhNGF 180 µg/ml eye drops solution|DRUG: vehicle eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Massage With Frankincense and Myrrh Oil in Treating Chronic Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: massage with frankincense and myyrh essential oil|OTHER: massage with carrier oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ARAMIS: Actions of tesaglitazaR on fAt Metabolism and Insulin Sensitivity
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: Tesaglitazar|DRUG: Metformin|BEHAVIORAL: Dietary and lifestyle modification counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study
Status: NOT_YET_RECRUITING
Conditions: Sensitivity and Specificity of Phase Contrast Mammography vs. Conventional Digital Mammography
Interventions: DIAGNOSTIC_TEST: Experimental Intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Pralatrexate With Vitamin B12 and Folic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Control Trial to Evaluate the Efficacy of Autologous Blood Injection Versus Local Corticosteroid Injection for Treatment of Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow|Epicondylitis, Lateral Humeral
Interventions: BIOLOGICAL: Autologous blood injection|DRUG: Local corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Digital Cognitive Training on the Functionality of Older Adults With Mild Cognitive Impairment (MCI)
Status: UNKNOWN
Conditions: Mild Cognitive Impairment|Aging
Interventions: BEHAVIORAL: digital cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics and Safety and Tolerability of a Single Oral Dose of Risdiplam Compared to Matched Healthy Participants With Normal Hepatic Function
Status: COMPLETED
Conditions: Muscular Atrophy, Spinal
Interventions: DRUG: Risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Health-risk Behaviours (Tobacco, Alcohol or Drug Consumption ; Nutrition ; Sedentary Lifestyle ; Sexual Practices) Among Cancer Survivors
Status: COMPLETED
Conditions: Cancer Remission
Interventions: BEHAVIORAL: Adult cancer survivors who have completed their heavy treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Oscillatory Versus Non-oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support
Status: WITHDRAWN
Conditions: Neonatal Respiratory Distress Related Conditions
Interventions: DEVICE: Regular Nasal CPAP using a conventional ventilator|DEVICE: High Frequency Nasal CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Efficacy of Androxal Treatment in Men With Secondary Hypogonadism
Status: COMPLETED
Conditions: Secondary Hypogonadism
Interventions: DRUG: Androxal|DRUG: Androxal
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct Cancers
Status: COMPLETED
Conditions: Cholangiocarcinoma|Tumor|Klatskin Tumor
Interventions: DRUG: Temoporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SpineJack® Versus Conservative Treatment Study (SPICO Study)
Status: COMPLETED
Conditions: Spinal Fractures|Vertebral Compression Fractures|Back Injuries|Trauma
Interventions: DEVICE: SpineJack system|DEVICE: Conservative management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HH-006 in Healthy Volunteers
Status: COMPLETED
Conditions: Hepatitis B
Interventions: DRUG: HH-006|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Safety and Efficacy of Two Treatments in the Treatment of Vulvar and Vaginal Atrophy
Status: COMPLETED
Conditions: Atrophy
Interventions: DRUG: estrace cream (Perrigo)|DRUG: estrace cream (Reference)|DRUG: Placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Molecular Test for Risk-stratification of Patients With High-risk Intestinal Metaplasia (GCEP2 Study)
Status: ACTIVE_NOT_RECRUITING
Conditions: Stomach Neoplasm
Interventions: PROCEDURE: Blood Collection, processing and analyses|PROCEDURE: Gastroscopy and biopsies collection|DIAGNOSTIC_TEST: Urea Breath Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Infant Behavioral Sleep Intervention: Comparative Efficacy
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Bedtime routine|BEHAVIORAL: Sleep schedule|BEHAVIORAL: Intervention (bedtime)|BEHAVIORAL: Intervention (after night wakings)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study of ONO-2333Ms in Patients With Recurrent Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ONO-2333Ms Experimental 2|DRUG: Placebo|DRUG: ONO-2333Ms Experimental 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Anticipatory Guidance in the Nursery and Its Impact on Non-urgent Emergency Department Visits"
Status: COMPLETED
Conditions: Health Knowledge, Attitudes, Practice|Sneezing|Constipation|Nasal Congestion and Inflammations
Interventions: BEHAVIORAL: Intensified anticipatory guidance|BEHAVIORAL: Routine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Status: UNKNOWN
Conditions: Stone, Kidney|Lithiasis Renal|Surgery
Interventions: PROCEDURE: Standard-PCNL|PROCEDURE: Mini-PCNL|PROCEDURE: SMP
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 177Lu-J591 and 177Lu-PSMA-617 Combination for mCRPC
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DRUG: 177Lu-PSMA-617|DRUG: 177Lu-J591|DRUG: 68Ga-PSMA-HBED-CC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinesio Taping and Calf Muscle Fatigue
Status: COMPLETED
Conditions: Fatigue
Interventions: OTHER: Kinesio Taping under tension.|OTHER: Kinesio Tape without tension|OTHER: Rigid Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stem Cell Transplant for Immunologic or Histiocytic Disorders
Status: COMPLETED
Conditions: Hemophagocytic Lymphohistiocytosis|X-Linked Lymphoproliferative Disorders|Chediak-Higashi Syndrome|Griscelli Syndrome|Immunologic Deficiency Syndromes|Langerhans-Cell Histiocytosis
Interventions: PROCEDURE: Stem Cell Transplant|DRUG: Fludarabine|DRUG: Melphalan|DRUG: Anti-thymocyte globulin (ATG)|DRUG: Campath 1H|DRUG: Cyclosporin A|DRUG: Mycophenolate mofetil|DRUG: Intravenous immunoglobulin (IVIG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: COMBINATION_PRODUCT: BDA MDI|COMBINATION_PRODUCT: AS MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Degradable Magnesium Metal Clips in Surgical Margins of Radical Surgery for Malignant Bone and Soft Tissue Tumors
Status: NOT_YET_RECRUITING
Conditions: Sarcoma, Soft Tissue|Sarcoma, Spindle Cell
Interventions: DEVICE: Biodegradable Magnesium Metal Clips
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NUVOLA TRIAL Open-label Multicentre Study
Status: UNKNOWN
Conditions: High Grade Serous Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: the Effect of Vitamin D in Crohn's Disease
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Crohn Disease
Interventions: DRUG: Vitamin D|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CVA21 and Pembrolizumab in NSCLC & Bladder Cancer (VLA-009 STORM/ KEYNOTE-200)
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer|Bladder Cancer
Interventions: BIOLOGICAL: CVA21/pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: H7N9 Mix and Match With AS03 and MF59 in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: AS03|DRUG: MF59|BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H7N9 A/Shanghai/2/2013
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: (TIMP-2)x(IGFPB7) to Predict Acute Kidney Injury (AKI) in Aortic Surgery
Status: COMPLETED
Conditions: Renal Failure|Dialysis|Aortic Surgery|Biomarker|Acute Kidney Injury
Interventions: OTHER: does not apply
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing a Wearable Digital Therapy for Youth With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DEVICE: FRx-001|DEVICE: FRx-003|DEVICE: FRx-004
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Additional Intravesical Instillation of Hyaluronic Acid/Chondroitin Sulfate to Transurethral Resection of Bladder Ulcer in Patients With Interstitial Cystitis/Bladder Pain Syndrome.
Status: TERMINATED
Conditions: Interstitial Cystitis
Interventions: DRUG: Hyaluronic acid/chondroitin sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PANFIRE Study: Irreversible Electroporation (IRE) to Treat Locally Advanced Pancreatic Carcinoma
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Carcinoma (LAPC)|Non-metastasized Unresectable Pancreatic Carcinoma|Pancreatic Cancer
Interventions: DEVICE: NanoKnife "Irreversible electroporation (IRE)"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Combined Measurements of Serum Infliximab and Anti-infliximab Antibodies in the Treatment of Patients With Crohns Disease Failing Infliximab Therapy
Status: UNKNOWN
Conditions: Crohn's Disease
Interventions: PROCEDURE: Measurement of serum infliximab and anti-infliximab antibodies|PROCEDURE: Treatment according to current standards without knowledge of serum infliximab and anti-infliximab Ab status
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Use of 68Ga PSMA-11 PET/CT in Diagnosing, Staging and Restaging Prostate Cancer
Status: NO_LONGER_AVAILABLE
Conditions: Prostate Cancer|Prostate Cancer Metastatic|Prostate Cancer Recurrent
Interventions: DRUG: 68Ga-PSMA-11|PROCEDURE: Positron Emission Tomography/Computed Tomography
Study Type: EXPANDED_ACCESS
Clinical trial: Single Arm Clinical Study on the Safety and Efficacy of Personalized KSX01-TCRT in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Refractory Solid Tumors|Relapsed Solid Tumors
Interventions: BIOLOGICAL: KSX01-TCRT cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)
Status: COMPLETED
Conditions: Fetal Atrial Flutter Without Hydrops|Fetal Supraventricular Tachycardia Without Hydrops|Fetal Supraventricular Tachycardia With Hydrops
Interventions: DRUG: Digoxin (monotherapy)|DRUG: Sotalol (monotherapy)|DRUG: Flecainide (monotherapy)|DRUG: Digoxin (dual therapy)|DRUG: Sotalol (dual therapy)|DRUG: Flecainide (dual therapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Neuroendocrine|Tumor, Neuroendocrine|Tumors, Neuroendocrine|Neuroendocrine; Carcinoma|Small Cell; Receptors
Interventions: DRUG: Belinostat|DRUG: Cisplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substrate Targeted Ablation Using the FlexAbility™ Ablation Catheter System for the Reduction of Ventricular Tachycardia
Status: TERMINATED
Conditions: Monomorphic Ventricular Tachycardia
Interventions: DEVICE: Cardiac catheter ablation with ICD/CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Satisfaction of Virtual vs In-Person Workup and Treatment of Lower Urinary Tract Symptoms.
Status: RECRUITING
Conditions: Urologic Diseases
Interventions: DEVICE: Stream Dx|DEVICE: DFree|DEVICE: TestCard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cell Surface Marker Expression in Autoimmune Diseases
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Sjogren's Syndrome|Multiple Sclerosis|Systemic Sclerosis|Crohn's Disease|Ulcerative Colitis|Inflammatory Myositis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults
Status: COMPLETED
Conditions: Lipoprotein Metabolism|PCSK9|Proteomics
Interventions: DRUG: control fish oil|DRUG: LCMUFA-rich saury oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Real Clinical Practice to Evaluate the Effects of Oral Dydrogesterone for Treatment of Confirmed Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Duphaston® (Dydrogesterone)|DRUG: Duphaston® (Dydrogesterone)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Lobeglitazone Versus Sitagliptin
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Lobelitazone 0.5mg|DRUG: Sitagliptin 100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of the Panbio™ COVID-19/Flu A&B Rapid Panel Professional Use Product Using Mid-Turbinate Nasal Swabs
Status: COMPLETED
Conditions: COVID-19|Influenza A|Influenza Type B
Interventions: DIAGNOSTIC_TEST: Panbio™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug-Eluting Stenting Followed by Cilostazol tREAtment Reduces SErious Adverse Cardiac Events (DECREASE-PCI)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Cilostazol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.
Status: RECRUITING
Conditions: Perioperative Pain Management
Interventions: DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine.
Status: COMPLETED
Conditions: Acute Pain|Chronic Pain|Neuropathic Pain
Interventions: DRUG: Placebo|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
Status: NOT_YET_RECRUITING
Conditions: Arthritis of Carpometacarpal Joint of Left Thumb|Arthritis of Carpometacarpal Joint of Right Thumb
Interventions: DRUG: Curcumin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pragmatic Trial Comparing Telehealth Care and Optimized Clinic-Based Care for Uncontrolled High Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Best Practice Clinic-Based Care|OTHER: Telehealth Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Safety and Effectiveness of the RxSight Light Adjustable Lens (LAL) in Subjects With Prior Corneal Refractive Surgery
Status: COMPLETED
Conditions: Aphakia|Cataract
Interventions: DEVICE: Light Adjustable lens (LAL) and Light Delivery Device (LDD)|DEVICE: Control IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mediterranean Diet and Probiotics in Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Mediterranean diet|DIETARY_SUPPLEMENT: Healthy diet (WHO recommendations)|DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Biopolis-MIX42
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Multifaceted Program to Prevent Postoperative Delirium in the Elderly
Status: TERMINATED
Conditions: Postoperative Delirium
Interventions: BEHAVIORAL: Multifaceted prevention program HELP(Hospital Elder Life Program)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: Sugammadex 2 mg/kg|DRUG: Sugammadex 4 mg/kg|DRUG: Neostigmine + Glycopyrrolate|DRUG: Neostigmine + Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Escalating Study of DAS181 in Adults
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: DAS181|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Health Coaching Effective for Improving Metabolic Health in People With Psychosis Disorders?
Status: UNKNOWN
Conditions: Psychotic Disorders|Metabolic Syndrome x
Interventions: BEHAVIORAL: Health Coaching|BEHAVIORAL: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of an Anorectal Fistula Plug With Sealing of the Internal Opening as a Treatment for Perianal Fistula
Status: TERMINATED
Conditions: Fistula in Ano
Interventions: DEVICE: CuraSeal Percutaneous Intraluminal Closure System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Cytomegalovirus (CMV)-Specific Cytotoxic T Cells for Cytomegalovirus (CMV) Reactivation
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: Cytomegalovirus (CMV)-Specific Cytotoxic T Cells (CTLs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Comparative Efficacy of Lucentis (Ranibizumab) 0.5mg Intravitreal Injection in Patients With Diabetic Macular Oedema (DME) With Well Controlled and Poorly Controlled Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetic Macular Oedema
Interventions: DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Treatment With HBIG+GM-CSF+HBV Vaccine for Chronic Hepatitis B Patients With HBeAg Seroconversion
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Drug|DRUG: GM-CSF control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Emixustat in Stargardt Disease
Status: COMPLETED
Conditions: Stargardt Disease
Interventions: DRUG: Emixustat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia
Status: RECRUITING
Conditions: Critical Limb Ischemia|Chronic Limb-Threatening Ischemia|Peripheral Arterial Disease
Interventions: DEVICE: LimFlow Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: DRUG: Daclizumab|DRUG: Methylprednisolone|DRUG: Mycophenolate mofetil|DRUG: Placebo|DRUG: cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: C1K|DRUG: C1K|DRUG: Placebo|DRUG: C1K|DRUG: C1K|DRUG: C1K
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Lung|Metastatic Osteosarcoma|Osteosarcoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Questionnaire Administration|PROCEDURE: Thoracoscopy|PROCEDURE: Thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endostar Combine With Radiotherapy in Brain Metastasis of NSCLC
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: endostar|DRUG: Placebos|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Status: COMPLETED
Conditions: Osteoarthritis|Dislocations|Inflammatory Arthritis|Rotator Cuff Tear|Shoulder Dislocation|Upper Limb Nerve Lesion|Shoulder Arthropathy|Elbow Arthropathy|Wrist Arthropathy|Arthropathy Unspecified, Involving Hand|Fracture, Shoulder|Fracture Elbow|Fracture Wrist and Hand|Dupuytren Contracture|Impingement Syndrome, Shoulder|Trigger Digit|Avascular Necrosis
Interventions: PROCEDURE: Shoulder arthroplasty|PROCEDURE: Elbow arthroplasty|PROCEDURE: Hand and wrist arthroplasty|PROCEDURE: Nerve decompression|PROCEDURE: Tendon repair|PROCEDURE: Joint stabilisation|PROCEDURE: Excision/division/release of palmar fascia|PROCEDURE: Surgical fixation of fractures|PROCEDURE: Soft tissue release/debridement/excision|PROCEDURE: Intra-articular injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p