pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Coffee Consumption on Glucose Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Coffee with Sugar|OTHER: Coffee without Sugar|OTHER: Decaffeinated Coffee without Sugar|OTHER: Water with Sugar|OTHER: Water without Sugar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral Care With 3% Hydrogen Peroxide (Oroxid®) in ICU - Effects on the Lower Airway Microbial Colonisation
Status: RECRUITING
Conditions: VAP - Ventilator Associated Pneumonia
Interventions: DRUG: Oroxid®|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rotator Interval and Intra-articular Corticosteroid Injection for Frozen Shoulder
Status: COMPLETED
Conditions: Adhesive Capsulitis
Interventions: DRUG: Triamcinolone hexacetonide|DRUG: Triamcinolone hexacetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
Status: COMPLETED
Conditions: Biopsy, Fine-needle|Pancreatic Neoplasm
Interventions: DIAGNOSTIC_TEST: Histologic evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Doxorubicin Hydrochloride Liposome Combined With Irinotecan Versus VIT Regimen in the Treatment of Pediatric Rhabdomyosarcoma
Status: NOT_YET_RECRUITING
Conditions: Rhabdomyosarcoma, Child
Interventions: DRUG: Doxorubicin Hydrochloride Liposome+Irinotecan|DRUG: Temozolomide+Irinotecan+Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive|Adenocarcinoma|Bile Duct Cancer|Biliary Tract Cancer|Bladder Cancer|Breast Cancer|Breast Neoplasm|Carcinoma, Ductal|Carcinoma, Hepatocellular|Cancer|Lung Cancer, Non-Small-Cell|Carcinoma, Ovarian Epithelial|Carcinoma, Small Cell|Carcinoma, Squamous|Carcinoma, Transitional Cell|Colorectal Cancer|Esophagogastric Junction Neoplasms|Inflammatory Breast Cancer|Stomach Neoplasms|Malignant Neoplasms|Ovarian Neoplasms|Pancreatic Cancer|HER2-positive Solid Tumors|HER2-positive Breast Cancer|HER2-positive Gastric Cancer|HER-2 Protein Overexpression|HER-2 Gene Amplification|Prostate Cancer|Head and Neck Cancer|Endometrial Cancer|Lung Cancer, Small Cell
Interventions: BIOLOGICAL: CT-0508|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Working Memory and Social-emotional Training for Preschoolers at Risk of ADHD
Status: COMPLETED
Conditions: ADHD|Time Perception Altered|Working Memory|Social Skills
Interventions: BEHAVIORAL: Game-like online working memory training|BEHAVIORAL: Game-like online social emotional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes of Exosomes and Biomarkers in Plasma and Alveolar Lavage Fluid of Patients With Sepsis Complicated With ARDS
Status: UNKNOWN
Conditions: Sepsis Complicated With ARDS
Interventions: DIAGNOSTIC_TEST: Blood samples and alveolar lavage fluid were collected
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of the EXOPULSE Mollii Ⓡ Suit in Patients With Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: DEVICE: EXOPULSE Mollii Ⓡ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MRI Guided Transurethral HIFU for Various Prostate Diseases
Status: ACTIVE_NOT_RECRUITING
Conditions: Localised Prostate Cancer|Locally Advanced Prostate Cancer|Locally Recurrent Prostate Cancer|Benign Prostatic Hyperplasia
Interventions: DEVICE: MRI guided transurethral HIFU ablation of prostatic tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients
Status: COMPLETED
Conditions: Vitreoretinal Surgery|Cognitive Function Abnormal|Intraoperative Monitoring
Interventions: DRUG: 2% lidocaine hydrochloride|DRUG: 0.5% levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Local Ischemic Postconditioning in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke|Mechanical Thrombectomy|Ischemic Postconditioning|Brain Edema|Neuroprotection
Interventions: PROCEDURE: rapid local ischemic postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pennsylvania Adolescent Smoking Study (PASStudy)
Status: UNKNOWN
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Motivational Interviewing (MI)|BEHAVIORAL: Structured Brief Advice (SBA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caveolin-1 and Vascular Dysfunction
Status: UNKNOWN
Conditions: Hypertension|Insulin Resistance
Interventions: DRUG: Para-aminohippuric Acid|DRUG: Angiotensin II|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Reduction of Prehospital Delays in Stroke and Transient Ischaemic Attack (TIA)
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: educational material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Induction Chemotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab|DRUG: Nab-paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Nephrectomy
Status: TERMINATED
Conditions: Kidney Diseases|Postoperative Complications
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prenatal Screening of Intestinal Malrotation With a Higher Risk of Volvulus.
Status: COMPLETED
Conditions: Postnatal Complication|Mesenteric Pregnancy
Interventions: OTHER: Ultrasound exam|OTHER: Fetal MRI|OTHER: Postnatal abdominal ultrasound|OTHER: Pediatric Follow up
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Sildenafil 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Psychosocial Benefits of Exercise in Endometrial Cancer Survivors
Status: TERMINATED
Conditions: Endometrial Cancer
Interventions: BEHAVIORAL: 150 weekly minutes walking|BEHAVIORAL: 75 weekly minutes walking|BEHAVIORAL: Stretching/Flexibility exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioavailability of N-acylethanolamines: an Ileostomy Study (NAE Study)
Status: RECRUITING
Conditions: Healthy Nutrition
Interventions: DIETARY_SUPPLEMENT: High-N-acylethanolamine meal|DIETARY_SUPPLEMENT: Low-N-acylethanolamine meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety of Oxaliplatin Combined With Capecitabine as Neoadjuvant Chemotherapy for Locally Advanced Colon Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine plus oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 12-week Dose-Ranging Trial in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: IMO-8400 Regimen 1|DRUG: IMO-8400 Regimen 2|DRUG: IMO-8400 Regimen 3|DRUG: Saline Placebo|DRUG: IMO-8400 Regimen 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Erector Spinae Plane Block Combined With General Anaesthesia Versus Conventional General Anaesthesia in Lumbar Spine Surgery
Status: UNKNOWN
Conditions: Anaesthetic Drugs, Hypotensive Drugs, Perioperative Analgesia
Interventions: PROCEDURE: Erector spinae plane block|DRUG: Multimodal analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Agili-C™ Implant Performance Evaluation in the Repair of Cartilage and Osteochondral Defects
Status: COMPLETED
Conditions: Cartilage or Osteochondral Defects in the Knee
Interventions: DEVICE: Agili-C™ implantation procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motor Recovery Training for Hand and Digits in Stroke and SCI
Status: UNKNOWN
Conditions: Acute Stroke|Cervical Spinal Cord Injury
Interventions: DEVICE: Hummingbird hand training device plus standard of care rehabilitation|OTHER: Comparison (sham) intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Generalized Versus Personalized Music Therapy in the ICU to Reduce Sedation
Status: UNKNOWN
Conditions: Critical Illness|Hypnotics and Sedatives|Music Therapy
Interventions: OTHER: Generalized Music therapy|OTHER: Personalized Music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation for the Individualization of Therapy in Adenocarcinomas of the Gastroesophageal Junction
Status: COMPLETED
Conditions: Adenocarcinoma of the Esophagogastric Junction
Interventions: DRUG: Oxaliplatin|DRUG: Epirubicin|DRUG: Capecitabine|DRUG: 5-FU|DRUG: Carboplatin|DRUG: Paclitaxel|RADIATION: radiation|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Salicylate on Platelet Function in CKD (Chronic Kidney Disease) Patients Treated With Aranesp
Status: RECRUITING
Conditions: Erythropoietin Adverse Reaction
Interventions: DRUG: Acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Determine the Therapeutic Effect of the Music Glove and Conventional Hand Exercises to Subacute Stroke Patients
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DEVICE: Music Glove|OTHER: Conventional Hand Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eatable Alphabet as a Nutrition Education Tool
Status: ENROLLING_BY_INVITATION
Conditions: Child Overnutrition|Child Obesity|Child Nutrition Disorders
Interventions: BEHAVIORAL: Eatable Alphabet|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hybrid Transvaginal-Transabdominal Endoscopic Surgery
Status: WITHDRAWN
Conditions: Gallstones|Appendicitis|Pelvic Pain
Interventions: PROCEDURE: Endoscopic Cholecystectomy|PROCEDURE: Endoscopic Appendectomy|PROCEDURE: Endoscopic Peritoneoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Piracetam on Diabetic Peripheral Neuropathy Patients
Status: NOT_YET_RECRUITING
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Piracetam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy
Status: TERMINATED
Conditions: Laparoscopic Colorectal Resection
Interventions: PROCEDURE: TAP block|PROCEDURE: Epidural|PROCEDURE: Paravertebral block|DRUG: Acetaminophen 1g IV|DRUG: Dexamethasone 4mg|DRUG: Midazolam up to 2mg|DRUG: Propofol 1-2.5 mg/kg|DRUG: Sevoflurane to keep a bispectral index of between 40-60|DRUG: Local infiltration with 10 mL of plain ropivacaine 0.25%|DRUG: Lidocaine|DRUG: Epinephrine|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Filgrastim, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: lomustine|DRUG: procarbazine hydrochloride|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Neuroprotective Effect of Cop-1 (Copaxone) in Acute Primary Angle Closure
Status: UNKNOWN
Conditions: Glaucoma, Angle-closure, Primary, Acute
Interventions: DRUG: Copaxone|DRUG: Placebo (buffered normal saline w/v)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Diabetes Related Cystic Fibrosis|Insulin-dependent Diabetes
Interventions: PROCEDURE: Combined pancreatic islet and lung transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib 20 mg/m^2|DRUG: Carfilzomib 70 mg/m^2|DRUG: Dexamethasone 40 mg|DRUG: Dara-SC 1800 mg|DRUG: Dexamethasone 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Clinical Outcomes of Different Wound Closure Methods in Immediate Implant Placement in the Aesthetic Zone
Status: UNKNOWN
Conditions: Tooth Fracture|Tooth Decay
Interventions: PROCEDURE: Immediate implant placement|PROCEDURE: Guided bone regeneration|PROCEDURE: Wound closure with gelatin sponge|PROCEDURE: Wound closure with collagen matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintenance Chemotherapy in High-metastatic Risk Nasopharyngeal Carcinoma Patients of N3 Stage
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Gemcitabine|RADIATION: standard chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 70 Years and Older
Status: COMPLETED
Conditions: Herpes Zoster|Herpes Zoster Vaccine
Interventions: BIOLOGICAL: Herpes Zoster Vaccine GSK1437173A|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Investigation on Zirconia-ceramic Three-unit Bridges With CAD-on Veneering
Status: COMPLETED
Conditions: Three-unit Posterior Bridges
Interventions: DEVICE: CAD/CAM Veneering|DEVICE: Manually layered veneering
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BMS-986442 With Nivolumab With or Without Chemotherapy in Solid Tumors and Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors|Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: BMS-986442|BIOLOGICAL: Nivolumab|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Pemexetred|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BIIB023|OTHER: Placebo (sterile normal saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 to Evaluate the Safety and Pharmacokinetic Characteristics of Fixed-dose Combination of YYC506
Status: UNKNOWN
Conditions: Dyslipidemias
Interventions: DRUG: YYC506-T and YYC506-A (phase 1)|DRUG: YYC506 (phase 1)|DRUG: YYC506-T and YYC506-A (phase 2)|DRUG: YYC506 (phase 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence and Determinants of Subclinical Cardiovascular Dysfunction in Adults With Type 2 Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Diabetic Cardiomyopathies
Interventions: DIAGNOSTIC_TEST: Cardiovascular magnetic resonance (CMR) imaging and magnetic resonance spectroscopy|DIAGNOSTIC_TEST: Transthoracic echocardiography|DIAGNOSTIC_TEST: Computed tomography coronary artery calcium scoring|DIAGNOSTIC_TEST: Cardiopulmonary exercise testing|DIAGNOSTIC_TEST: Manganese-enhanced magnetic resonance imaging (MEMRI)|DIAGNOSTIC_TEST: Ambulatory blood pressure monitoring|DIAGNOSTIC_TEST: Accelerometer watch|DIAGNOSTIC_TEST: Blood tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: CT1812|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study for Depigoid Birch: 4 Doses in Patients With Allergic Rhinitis/Rhinoconjunctivitis +-Asthma
Status: COMPLETED
Conditions: Allergic Rhinitis and/or Rhinoconjunctivitis +- Asthma|Immunotherapy, Allergen
Interventions: BIOLOGICAL: Allergoid, allergenic extract of 100% Birch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adult Attention Deficit Hyperactivity Disorder (ADHD) Study With Amphetamine Sulfate
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Amphetamine Sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Playful Learning in Infancy Program
Status: RECRUITING
Conditions: Parent-Child Relations|Infant Development
Interventions: BEHAVIORAL: Playful Learning in Infancy Program|BEHAVIORAL: Postnatal care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MR-Lymphography and Lymph Node Staging in Prostate Cancer
Status: UNKNOWN
Conditions: Prostatic Neoplasms|Lymphatic Metastasis
Interventions: PROCEDURE: Ferumoxtran-10 enhanced MRI (MRL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Influence of of Cream With the Silver Fir Wood Extract (Belinal) on Skin
Status: COMPLETED
Conditions: Wrinkles|Ageing|Photoprotection|Skin Care|Skin Cream
Interventions: OTHER: Placebo cream|OTHER: Belinal cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: PROCEDURE: T Cell Proliferation and Autoreactivity Assays|PROCEDURE: Cellular Immunoblot Assays|PROCEDURE: Tetramer Studies|PROCEDURE: Cytokine ELISPOT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Assess the Effect of Leucine Along With Resistance Exercise on Muscle Strength and Quality of Life in Elders
Status: COMPLETED
Conditions: Ageing
Interventions: DIETARY_SUPPLEMENT: L-leucine.|DIETARY_SUPPLEMENT: Maltodextrin.|BEHAVIORAL: Exercise program.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Anti-ILT3 CAR-T Therapy for R/R AML(M4/M5)
Status: RECRUITING
Conditions: AML M4|AML M5
Interventions: BIOLOGICAL: anti-ILT3 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Versus Conventional Ventilation Mode During Mobilization Period in Critical Care Patients
Status: COMPLETED
Conditions: Critical Ill Patients|Ventilated Patients
Interventions: OTHER: Nursing 1 : INTELLIVENT-ASV|OTHER: Nursing 2 : INTELLIVENT-ASV|OTHER: Nursing 1 : Conventional mode|OTHER: Nursing 2 : Conventional mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hemostasis Pad Using Chitosan After Invasive Percutaneous Procedures
Status: UNKNOWN
Conditions: Coronary Artery Disease|Puncture
Interventions: DEVICE: ezClot (hemostasis pad)|DEVICE: BloodSTOP ix pad|DEVICE: Rotary compression device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Methylprednisolone in Endovascular Aortic Repair
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: DRUG: Methylprednisolone|DRUG: Physiological Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-treatment Exercises Versus Post-treatment Exercises for Dysphagia
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: OTHER: Pre-treatment swallowing exercises|OTHER: Post-treatment swallowing exercises.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Chemotherapy & Bevacizumab for Human Epidermal Growth Factor Receptor 2 (HER2)/Neu-Negative Stage II/III Breast Cancer
Status: TERMINATED
Conditions: HER2-negative Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|BIOLOGICAL: bevacizumab|DRUG: paclitaxel|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|BIOLOGICAL: pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of 20vPnC in Toddlers With 2 Prior Doses of Prevenar 13
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immune Markers in Pediatric ITP on Second Line Therapy
Status: NOT_YET_RECRUITING
Conditions: ITP - Immune Thrombocytopenia
Interventions: DIAGNOSTIC_TEST: complete blood count, CD3+ , CD4+ , CD8+, CD16+, CD56+, IFN-γ.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Safety, Tolerability and Efficacy of Treatment With AP1189 in Early RA Patients With Active Joint Disease
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: 50 mg AP1189|DRUG: AP1189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Web-Based Health Information on Risk Behavior for Youth With Type 1 Diabetes in College
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Peer-Based Web-Based Health Information|BEHAVIORAL: Provider-Based Web-Based Health Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial of Dyanavel XR in Treating Co-occurring Fatigue Symptoms in Adults With Attention Deficit Hyperactivity Disorder (ADHD).
Status: NOT_YET_RECRUITING
Conditions: Fatigue|Attention Deficit Hyperactivity Disorder|Attention Deficit Disorder
Interventions: DRUG: Dyanavel XR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dorzagliatin and 1st Phase Insulin and Beta-cell Glucose Sensitivity in IGT and NGT
Status: UNKNOWN
Conditions: Glucose Intolerance
Interventions: DRUG: Dorzagliatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing in Predicting Response to Paclitaxel in Women With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: paclitaxel|GENETIC: microarray analysis|PROCEDURE: biopsy|PROCEDURE: neoadjuvant therapy|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fluoroscopic vs Ultrasound Guided Sacroiliac (SI) Joint Radiofrequency Ablation
Status: WITHDRAWN
Conditions: Sacroiliac Joint Somatic Dysfunction
Interventions: PROCEDURE: Fluoroscopic-guided Radiofrequency Ablation|PROCEDURE: Ultrasound-guided Radiofrequency Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Mindful Tai Chi on Obese or Overweight Adults: A Randomized Controlled Clinical Trial
Status: TERMINATED
Conditions: Obesity|Adult|Healthy
Interventions: BEHAVIORAL: Mindful Tai Chi Intervention|BEHAVIORAL: Mindfulness Meditation|BEHAVIORAL: Mall Walking|BEHAVIORAL: Weekly Discussion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Predictives Factors of Cardiac Resynchronization Therapy: a Multimodal Analysis Using 2D Speckle Tracking Echocardiography Coupled With MIBG Myocardial Scintigraphy and Heart Failure Biomarkers
Status: UNKNOWN
Conditions: Heart Failure|Reduced Ejection Fraction
Interventions: OTHER: cardiac resynchronisation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Transverse Supraumbilical Versus Pfannenstiel Incision for Cesarean Section in Morbidly Obese Women
Status: COMPLETED
Conditions: Cesarean Section
Interventions: PROCEDURE: transverse supraumbilical|PROCEDURE: pfannenstiel incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Pharmacokinetics, Safety and Tolerability Study of TMC435 as Part of a Treatment Regimen for Hepatitis C-Infected Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: TMC435|DRUG: Peginterferon-alpha (PegIFNα-2a)|DRUG: Ribavirin (RBV)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of LuminoMark Injection in Patients With Nonpalpable Breast Lesions(Phase 3)
Status: COMPLETED
Conditions: Breast Diseases
Interventions: DRUG: LuminoMark inj.(Conc. for fluorescence)|DRUG: Charcotrace Inj.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
Status: COMPLETED
Conditions: Vertigo|Dizziness
Interventions: DEVICE: VRT Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention of Recurrent Vulvovaginal Candidiasis With Lactibiane Candisis 5M®
Status: TERMINATED
Conditions: Vaginal Candidiasis
Interventions: DIETARY_SUPPLEMENT: Lactibiane candisis 5M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Dexmedetomidine Intra Venous Arthroplasty
Status: COMPLETED
Conditions: Primary Total Knee Arthroplasty
Interventions: DRUG: Dexmedetomidine|DRUG: sodium chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Early Weight Loss Following Laparoscopic Sleeve Gastrectomy Affect Long-term Outcomes
Status: COMPLETED
Conditions: Hypertension|Diabetes Mellitus, Type 2|Gastrostomy|Morbid Obesity|Weight Loss
Interventions: PROCEDURE: Laparoscopic sleeve gastrectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Different Volatile Anaesthetics and the Depth of Long Term ICU Sedation
Status: COMPLETED
Conditions: Intensive Care Unit Syndrome
Interventions: DRUG: Isoflurane|DRUG: Sevoflurane|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate if ID-085 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ID-085|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Menopause After Cancer Study
Status: COMPLETED
Conditions: Menopause|Cancer|Insomnia
Interventions: COMBINATION_PRODUCT: Citalopram +/- Gabapentin + Sleepio + support person
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency of a New Therapy to Treat Stenosis of Coronary Vessels in Comparison With Two Already Admitted Therapies
Status: UNKNOWN
Conditions: Stable or Unstable Angina Pectoris|Myocardial Ischemia
Interventions: DRUG: local intracoronary dosis of Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Distraction in the Postoperative Period of Pediatric Patients Undergoing Outpatient Surgery
Status: RECRUITING
Conditions: Pain, Postoperative|Surgery|Child, Only
Interventions: OTHER: Watching Cartoons|OTHER: ball spin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: The Effects of Isoflavones on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients
Status: UNKNOWN
Conditions: Peritoneal Dialysis Patients
Interventions: DIETARY_SUPPLEMENT: soy isoflavone|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Respiratory Mechanics Measurement of Ventilated Patients Through Low-frequency Oscillometry Technique
Status: RECRUITING
Conditions: Ventilator Lung
Interventions: DIAGNOSTIC_TEST: compliance measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Assess the Efficacy of MSC in Patients With ARDS Due to COVID-19
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome|COVID-19 Pneumonia
Interventions: BIOLOGICAL: Mesenchymal stromal cells|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Control Trial of Using Tongue Acupuncture in Autistic Spectrum Disorder Using PET Scan for Clinical Correlation
Status: COMPLETED
Conditions: Autism|Autistic Disorder
Interventions: PROCEDURE: Tongue Acupuncture (Procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PWID; Longitudinal S Aureus Colonization Pattern and the Impact on Infection Frequency by Regular Showers With Chlorhexidine
Status: COMPLETED
Conditions: Intravenous Drug Abuse, S Aureus Colonization
Interventions: DRUG: Chlorhexidine Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Filter Lenses for the Prevention of Migraine Attacks
Status: NOT_YET_RECRUITING
Conditions: Migraine|Glasses|Headache|Visual Impairment
Interventions: DEVICE: Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VEG111485: A QTc Study of Pazopanib
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib|OTHER: Placebo for pazopanib|DRUG: Moxifloxacin|OTHER: Placebo for moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Urethral Sterilization With Chlorhexidine Digluconate to Facilitate Primary Repair & Same-Session Implantation
Status: UNKNOWN
Conditions: Penile Prosthesis; Complications
Interventions: DRUG: Chlorhexidine gel will be prepared according to an international product Instillagel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Antibiotic Prophylaxis in Oncological Surgery of Breast
Status: COMPLETED
Conditions: Breast Neoplasms|Breast-Conserving Surgery|Wound Infection|Antibiotic Prophylaxis
Interventions: DRUG: Cefazolin|DRUG: sterile saline|PROCEDURE: oncologic breast surgery|OTHER: Microbiology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Performance of Posterior Glass Ionomer Restorations in Adolescents (KETAC)
Status: COMPLETED
Conditions: Dental Caries
Interventions: DEVICE: Ketac Universal|DEVICE: Ketac Molar Quick
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Ranolazine in Microvascular Coronary Dysfunction (MCD): Impact on Angina Myocardial Ischemia
Status: COMPLETED
Conditions: Microvascular Coronary Dysfunction (MCD)
Interventions: DRUG: Ranolazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock
Status: RECRUITING
Conditions: Cardiogenic Shock
Interventions: DEVICE: CytoSorb|OTHER: VA-ECMO only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Focused and Radial Extracorporeal Shock Waves on Post-stroke Hypertonia
Status: COMPLETED
Conditions: Spasticity
Interventions: DEVICE: Focused shock wave|DEVICE: Radial shock wave
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open Label Trial for Treating Carpometacarpal Osteoarthritis of the Thumb: Pilot Study
Status: COMPLETED
Conditions: Carpometacarpal Osteoarthritis
Interventions: DEVICE: Synvisc (hylan G-F20)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI)
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: BIOLOGICAL: PNT001|BIOLOGICAL: %5 dextrose for infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Icotinib in Combination With Chemotherapy Versus Chemotherapy Alone in Patients Progressed After Icotinib Treatment
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Chemotherapy|DRUG: Icotinib+chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of TC-5619 as Augmentation Therapy to Improve Negative Symptoms and Cognition in Outpatients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Negative Symptoms|Cognitive Dysfunction
Interventions: DRUG: TC-5619|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estradiol and Progesterone in Hospitalized COVID-19 Patients
Status: TERMINATED
Conditions: Covid19
Interventions: OTHER: Placebo injection and placebo pill|DRUG: Estradiol Cypionate 5 mg/ml|DRUG: Progesterone 200 mg Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Anti-citrullinated Protein Antibody Status on Treatment Response and Treatment Persistence in Participants With Rheumatoid Arthritis (RA) Who Are Treated With Abatacept or Tumor Necrosis Factor Inhibitors in Australia
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Non-Interventional|OTHER: Non-Interventional
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Efficacy and Safety of Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis.
Status: TERMINATED
Conditions: Endophthalmitis
Interventions: DRUG: Moxifloxacin|DRUG: No injection of moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of a Topical Nasal Spray to Ease the Symptoms of Hayfever
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DEVICE: C-1266-7|DEVICE: C-1266-6 (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy in Extensive-Stage Small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: QL1706|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Secukinumab for the Treatment of Alopecia Areata
Status: TERMINATED
Conditions: Alopecia Areata
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Real Time Characterization in Artificial Intelligence-assisted Colonoscopy
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer|Colorectal Adenoma|Colorectal Neoplasms
Interventions: DEVICE: AI-assisted colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BMT Autologous MSCs for GvHD
Status: COMPLETED
Conditions: Graft Versus Host Disease|Acute Graft Versus Host Disease|Chronic Graft Versus Host Disease
Interventions: BIOLOGICAL: Autologous mesenchymal stromal cells (MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Haploidentical Stem Cell Transplant With or Without NK Cell Infusion in AML and MDS
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Myelodysplasia
Interventions: BIOLOGICAL: Haplo SCT with NK cells|BIOLOGICAL: Haplo SCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of NMES as an Add-On to Exercise Program in Degenerative Meniscus Tears
Status: RECRUITING
Conditions: Degenerative Disease|Meniscus Tear|Knee Pain Swelling
Interventions: OTHER: Exercise|OTHER: Neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Melanoma Metastasized to the Brain and Steroids
Status: RECRUITING
Conditions: Malignant Melanoma
Interventions: DRUG: Pembrolizumab Injection [Keytruda]|DRUG: Ipilimumab Injection [Yervoy]|DRUG: Nivolumab Injection [Opdivo]|DRUG: Encorafenib|DRUG: Binimetinib|DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Rotational CT Angiogram With Embolization Guidance and CBCT in Prostatic Artery Embolization
Status: COMPLETED
Conditions: Enlarged Prostate
Interventions: DEVICE: cone-beam CT 3D Emboguide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Early Stage Non-Small Cell Lung Cancer
Interventions: DRUG: Vancomycin|RADIATION: Precision hypofractionated radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 Plus Gefitinib (Iressa) In Patients With Advanced Renal Cell Carcinoma
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Gefitinib + Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Relative Bioavailability and Safety of the AG-348 Tablet and Capsule Formulations in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AG-348 Sequence A|DRUG: AG-348 Sequence B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Correlation of Spinopelvic Movement With Lateral Radiographs
Status: COMPLETED
Conditions: Spinopelvic Relationships as They Relate to Total Hip Arthroplasty's
Interventions: DEVICE: MetaWear Sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH