pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.
Status: COMPLETED
Conditions: Hyperlipidemia|Dyslipidemia|Hypercholesterolemia
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Physical Therapy on the Multisystems of Children With Cerebral Palsy: a Longitudinal Study
Status: RECRUITING
Conditions: Cerebral Palsy|Physical Therapy Modalities
Interventions: OTHER: Bobath Concept|OTHER: Pediasuit|OTHER: Locomotor training|OTHER: Stretching|OTHER: Psychomotricity|OTHER: Virtual reality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Application of Non-invasive and Cellular Level Resolution Fullfield Optical Coherence Tomography: Establishment and Analysis of Subcutaneous Cellular Level Image Database of Anatomical Locations in Healthy Volunteers and Evaluation of Usability
Status: COMPLETED
Conditions: Healthy Skin|Nevus
Interventions: DEVICE: ApolloVue® S100 Image System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose Ranging Study for Indacaterol in Japanese Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol|DRUG: Placebo|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors
Status: COMPLETED
Conditions: Gastrointestinal Tract|Gastrointestinal Stromal Tumor
Interventions: DEVICE: Echotip ProCoreⓇ HD Ultrasound Biopsy Needle
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Skin-to-skin After Delivery in Preterm Infants Born at 28-32 Weeks of Gestation
Status: ACTIVE_NOT_RECRUITING
Conditions: Premature Birth
Interventions: BEHAVIORAL: skin-to-skin|BEHAVIORAL: standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of FP MDPI Compared With FS MDPI in Adolescent and Adult Patients With Persistent Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FS MDPI|DRUG: Fp MDPI|DRUG: Placebo MDPI|DRUG: Albuterol/salmeterol HFA MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: This Is A Study Of Bioavailability And Food Effect For Fesoterodine.
Status: COMPLETED
Conditions: Overactive Bladder (OAB) With Symptoms of Frequency, Urgency, and Urgency
Interventions: DRUG: fesoterodine|DRUG: fesoterodine|DRUG: fesoterodine|DRUG: fesoterodine|DRUG: fesoterodine|DRUG: fesoterodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Procedures While Wearing CBRNe Protective Equipment
Status: COMPLETED
Conditions: Cardiac Arrest|Pneumothorax|Hemorrhage
Interventions: OTHER: Use of Personal Protective Equipment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Weight Management for Adolescents With IDD
Status: COMPLETED
Conditions: Developmental Disabilities|Weight Loss|Body Weight|Down Syndrome|Body Weight Changes|Intellectual Disability
Interventions: DIETARY_SUPPLEMENT: Enhanced Stop Light Diet (eSLD)|DIETARY_SUPPLEMENT: Conventional Diet (CD)|BEHAVIORAL: Face-to-face (FTF)|BEHAVIORAL: Technology (TECH)|OTHER: iPad with FaceTime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Nivolumab Safety and Pharmacokinetics in Patients With Severe Sepsis or Septic Shock.
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IV Colon Cancer|Stage IV Rectal Cancer
Interventions: DRUG: aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VR Based Simulation in the Preparation of Children for MRI - MRVR
Status: RECRUITING
Conditions: Children, Only|Anesthesia
Interventions: OTHER: VR|OTHER: Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Nitazoxanide Combined With Peginterferon Compared to Peginterferon Monotherapy in the Treatment of Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis C
Interventions: DRUG: Nitazoxanide plus peginterferon alfa-2b|DRUG: Peginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Redes III Patient Navigator Qol Study
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer|Colorectal Cancer
Interventions: BEHAVIORAL: PN+LCNC|BEHAVIORAL: PN Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy of Endermologie in Treatment of Cellulite and Body Contouring
Status: COMPLETED
Conditions: Cellulite|Body Contouring
Interventions: DEVICE: Dhermia® - Industra Mecânica Fina Ltda
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma and Scarring of Diabetic Ulcers
Status: COMPLETED
Conditions: Chronic Skin Ulcer|Diabetic Foot|Plasma Protein; Transport Protein
Interventions: OTHER: Application of platelet rich plasma in chronic wounds of diabetic origin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Setrobuvir in Combination With Pegasys (Peginterferon Alfa-2a) and Copegus (Ribavirin) in Patients With Genotype 1 Chronic Hepatitis C
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: peginterferon alfa-2a [Pegasys]|DRUG: placebo|DRUG: ribavirin [Copegus]|DRUG: setrobuvir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate the Efficacy and Safety of MBA-P01 in Treatment of Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines
Interventions: DRUG: MBA-P01(Botulinum toxin A)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome
Interventions: DRUG: ZARNESTRA, tipifarnib, R115777
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigate Efficacy & Safety of RO4995819 vs. Placebo as Adjunct Tx in Patients w/Major Depressive Disorder
Status: WITHDRAWN
Conditions: Depression|Major Depressive Disorder
Interventions: BIOLOGICAL: RO4995819
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility
Status: TERMINATED
Conditions: Primary Ovarian Insufficiency|Unexplained Infertility
Interventions: DIETARY_SUPPLEMENT: Dehydroepiandrosterone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Womens Study to Alleviate Vasomotor Symptoms
Status: ACTIVE_NOT_RECRUITING
Conditions: Hot Flashes
Interventions: OTHER: low-fat vegan diet with 1/2 cup soybeans daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Botulinum Toxin to Treat Restless Legs Syndrome
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Physiotherapy in Hemodynamics and Childrens Respiratory Mechanics
Status: TERMINATED
Conditions: Respiratory Insufficiency|Children
Interventions: OTHER: Bag Squeezing|OTHER: Thoracic vibrocompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clareon Intraocular Lens Stability in Vitrectomy Patients: CLOVE Study
Status: COMPLETED
Conditions: Senile Cataract|Epiretinal Membrane|Vitreous Hemorrhage
Interventions: DEVICE: Clareon|DEVICE: Tecnis 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of PP-001 Eye Drops in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Keratoconjunctivitis|Ocular Surface Disease
Interventions: DRUG: PP-001|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Chemotherapy, Oregovomab and Nivolumab in Patients With Epithelial Cancer of Ovarian, Tubal or Peritoneal Origin
Status: UNKNOWN
Conditions: Epithelial Ovarian Cancer
Interventions: DRUG: Oregovomab|DRUG: Nivolumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Healthy Volunteers|Pharmacokinetics|Pioglitazone|Drug-drug Interaction|Amount of Pioglitazone in Blood
Interventions: DRUG: fostamatinib|DRUG: pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Natural Compounds to Reduce Nitrite in Meat Products
Status: COMPLETED
Conditions: Colon Cancer
Interventions: DIETARY_SUPPLEMENT: Processed meat product|DIETARY_SUPPLEMENT: White meat wash-out|DIETARY_SUPPLEMENT: Processed meat products enriched with natural compounds|DIETARY_SUPPLEMENT: Drinking water containing nitrate up to acceptable daily intake level (ADI = 3.7 mg/kg bw) in combination with 300 grams of processed meat, white meat or processed meat enriched with natural compounds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population
Status: UNKNOWN
Conditions: Ventricular Arrhythmia
Interventions: PROCEDURE: Radiofrequency catheter ablation|DRUG: Metoprolol|DRUG: Verapamil|DEVICE: NAVI-STAR® RMT ThermoCool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HAIC With Oxaliplatin, 5-FU and Bevacizumab Plus Intravenous Toripalimab for Advanced BTC
Status: COMPLETED
Conditions: Advanced Biliary Tract Cancer
Interventions: DRUG: OXA, 5-FU and bevacizumab plus Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Effect of Mechanical Ventilation in Children With Right Ventricular Hypertrophy
Status: UNKNOWN
Conditions: Heart-lung Interaction|Right Ventricular Hypertrophy|Postoperative Care|Congenital Heart Disease|Mechanical Ventilation
Interventions: DEVICE: Mechanical ventilation with NAVA mode|DEVICE: Mechanical ventilation with PCV mode|DEVICE: Mechanical ventilation with PSV mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Non-invasive Bladder Stimulation Technique on Collecting Urine Specimen in Infants Under One Year Old
Status: UNKNOWN
Conditions: Urine Specimen Collection
Interventions: PROCEDURE: Bladder stimulation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites
Status: COMPLETED
Conditions: Plasmodium Falciparum Infection
Interventions: BIOLOGICAL: Genetically-attenuated p52-/p36-/sap1- Plasmodium falciparum parasite (GAP3KO) strain|OTHER: Malaria challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Symbicort on the Ventilatory Kinematics
Status: TERMINATED
Conditions: Chronic Obstructive Lung Disease
Interventions: DRUG: Budesonide|DRUG: Symbicort
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of EC145 Alone Versus EC145+Docetaxel Versus Docetaxel Alone in Participants With FR(++) 2nd Line Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: EC145|DRUG: EC145 + Docetaxel|DRUG: Docetaxel|DRUG: EC20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cow's Milk Allergy in Infants With Obstructive Sleep Apnea (OSA)
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea Syndrome
Interventions: DIETARY_SUPPLEMENT: Non milk or soy based formula|DIETARY_SUPPLEMENT: milk based formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Drug Interaction Study With Lu AG06466 in Young Healthy Men
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lu AG06466|OTHER: Midazolam|OTHER: Metoprolol|OTHER: Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Intervention for Low Income Depressed Smokers in Drug Treatment
Status: COMPLETED
Conditions: Cigarette Smoking|Drug Use
Interventions: BEHAVIORAL: Standard Treatment|BEHAVIORAL: BAD-AS|DRUG: Transdermal Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Huaier Granule in Patients With Stage I Primary Ovarian Fallopian Tube Cancer After Peritoneal Cancer
Status: NOT_YET_RECRUITING
Conditions: Primary Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Cancer
Interventions: DRUG: Huaier granule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving ABBV-383 as an Intravenous (IV) Infusion
Status: RECRUITING
Conditions: Immunoglobulin Light Chain (AL) Amyloidosis
Interventions: DRUG: ABBV-383
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Diagnostic Performance of Skeletal 99mTc-MDP SPECT/CT in Patients With Low Back Pain
Status: UNKNOWN
Conditions: Low Back Pain, Mechanical
Interventions: DEVICE: 99mTc-MDP SPECT/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of the Hydrophobic Intraocular Lens AsqelioTM Monofocal With Biaspheric Design
Status: NOT_YET_RECRUITING
Conditions: Cataract|Pseudophakia
Interventions: DEVICE: LIO ASQELIO TM monofocal QLIO130C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Changing in Skin Physiology After Microdroplet Placement of Stabilized Hyaluronic Acid in Aging Faces
Status: COMPLETED
Conditions: Aging
Interventions: DEVICE: Restylane Vital
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence.
Status: WITHDRAWN
Conditions: Cirrhosis|Alcohol Dependence|Nalmefene
Interventions: DRUG: Nalmefene (Selincro®) 18 mg tablet|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple- Dose BIVV009 in Participants With Chronic Immune Thrombocytopenia (ITP)
Status: COMPLETED
Conditions: Purpura, Thrombocytopenic, Idiopathic
Interventions: DRUG: BIVV009 6.5 grams|DRUG: BIVV009 7.5 grams
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT Combined With Avelumab (Anti-PD-L1) for Management of Early Stage Non-Small Cell Lung Cancer (NSCLC)
Status: TERMINATED
Conditions: Early Stage Non-Small Cell Lung Cancer
Interventions: DRUG: Avelumab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apolizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Noncontiguous Stage II Small Lymphocytic Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Stage III Small Lymphocytic Lymphoma|Stage IV Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: apolizumab|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unilateral Versus Bilateral TLIF for Degenerative Lumbar Spondylolisthesis
Status: UNKNOWN
Conditions: Degenerative Spondylolisthesis|Transforaminal Lumbar Interbody Fusion
Interventions: PROCEDURE: Unilateral Transforaminal Interbody fusion|PROCEDURE: Bilateral Transforaminal Interbody fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combinition of Camrelizumab in Second-line Neoadjuvant Chemotherapy and Adjuvant Therapy
Status: RECRUITING
Conditions: HER2-negative Breast Cancer|Neoadjuvant Therapy|Pathological Complete Response|Immunotherapy|Vinorelbine|Cisplatin
Interventions: DRUG: Camrelizumab with vinorelbine and cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internal Radiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|PROCEDURE: Lumpectomy|RADIATION: brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Anesthetic for Procedures Through the Nose
Status: COMPLETED
Conditions: Drug Reaction to Analgesic Nos
Interventions: DRUG: RX0041 4%|DRUG: Placebo|DRUG: RX0041 8%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Observational Study of the Value of Using Obstructive Sleep Apnea-hypopnea Syndrome (CPAP) Ventilation on the Occurrence of Respiratory and Cardiovascular Complications in Patients at High Risk of Obstructive Apnea Syndrome During Postoperative Sleep Surgery of a Major Abdominal Surgery.
Status: COMPLETED
Conditions: Major Abdominal Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers
Status: COMPLETED
Conditions: Acute Pain|Respiration|Sedation
Interventions: DRUG: Remifentanil+clonidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Subjects
Status: TERMINATED
Conditions: Pharmacokinetic|Drug Combination|Healthy
Interventions: DRUG: Artemether-lumefantrine|DRUG: Amodiaquine|DRUG: Artemether-lumefantrine|DRUG: Artemether-lumefantrine + Amodiaquine|DRUG: Primaquine|DRUG: Artemether-lumefantrine + Primaquine|DRUG: Artemether-lumefantrine + Amodiaquine + Primaquine|DRUG: Artemether-lumefantrine + Primaquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prosthetic Complications of Screw Retained Restoration
Status: UNKNOWN
Conditions: Edentulous Jaw|Edentulous Alveolar Ridge|Edentulous Mouth
Interventions: PROCEDURE: titanium bases using intra oral luting cement technique|PROCEDURE: transmucosal abutment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bronchodilators and Oxygen Kinetics With Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Combivent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Peat and Apple Extract on Muscle ATP and Exercise Performance
Status: COMPLETED
Conditions: Caffeine and Endurance Performance
Interventions: DIETARY_SUPPLEMENT: ElevATP supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TEmporary Spinal CoRd StiMulatIon to PrevenNt Atrial FibrillaTION AFter Cardiac Surgery
Status: UNKNOWN
Conditions: Coronary Artery Disease|Atrial Fibrillation
Interventions: DEVICE: Temporary spinal cord stimulation|PROCEDURE: Coronary artery bypass grafting|DRUG: B-blockers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Safety, Drug Levels and Effectiveness of CC-92480 (BMS-986348) in Combination With Other Treatments in Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: CC-92480|DRUG: Tazemetostat|DRUG: BMS-986158|DRUG: Trametinib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin in Traumatic Brain Injury (EPO-TBI)
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Epoetin Alfa|DRUG: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACALA-R In Predominantly Demyelinating IgM Mediated Neuropathy
Status: RECRUITING
Conditions: IgM MGUS|Waldenstrom Macroglobulinemia|Neuropathy;Peripheral
Interventions: DRUG: Acalabrutinib|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Safety And Tolerability Of Different Doses Of PF-06444753 And PF-06444752 In Subjects With Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: BIOLOGICAL: IGE-1|BIOLOGICAL: IGE-2|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of PowerScope and Forsus
Status: COMPLETED
Conditions: Class II Division 1 Malocclusion
Interventions: DEVICE: Powerscope placed bilaterally for class II correction|DEVICE: Group 2 Forsus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Mechanisms of Action of Lifibrol and Pravastatin
Status: COMPLETED
Conditions: Hypercholesterolemia|Hyperlipoproteinemia
Interventions: DRUG: Pravastatin|DRUG: Lifibrol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Differentiated Care for Improved Health Systems Efficiency and Health Outcomes in Zambia
Status: COMPLETED
Conditions: HIV
Interventions: OTHER: START|OTHER: CAG|OTHER: UAG|OTHER: FAST-TRACK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: QUILT-3.002: N-803 in Patients With Relapse/Refractory iNHL in Conjunction With Rituximab
Status: TERMINATED
Conditions: Relapsed/Refractory Indolent B Cell Non-Hodgkin Lymphoma
Interventions: BIOLOGICAL: Rituximab|BIOLOGICAL: N-803
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of PEG-rIL-29 Plus Ribavirin to Treat Chronic Hepatitis C Virus Infection
Status: UNKNOWN
Conditions: Hepatitis C, Chronic
Interventions: DRUG: PEG-rIL-29|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar or Schizophrenia Illness
Status: COMPLETED
Conditions: Obesity|Ketogenic Dieting|Metabolic Syndrome|Bipolar Disorder|Schizophrenia|Weight Gain|Psychotropic Agents Causing Adverse Effects in Therapeutic Use|Brain Metabolic Disorder
Interventions: OTHER: LCHF, Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-blind Randomized, Placebo-controlled, Crossover Study of Single Doses of OROS Methylphenidate Hydrochloride (CONCERTA) and Long-acting Methylphenidate Hydrochloride (RITALIN LA) in Healthy Adults
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: OROS methylphenidate HCl|DRUG: SODAS methylphenidate HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose:
Clinical trial: Outcome of Two Protocols in Poor Responders in Assisted Reproductive Technology (ART) Cycle
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Microdose GnRh|DRUG: Flare up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Arcuate Incisions Performed With the iFS Femtosecond Laser System
Status: COMPLETED
Conditions: Corneal Astigmatism
Interventions: DEVICE: iFS Femtosecond Laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Propionibacterium Freudenreichii for the Treatment of Mild to Moderate Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: OTHER: Probiotics in the form of cheese portion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy
Status: RECRUITING
Conditions: Colon Disease
Interventions: DRUG: Picoprep|DRUG: Plenvu
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Treatment of Angina in Women With Microvascular Dysfunction
Status: COMPLETED
Conditions: Angina Pectoris|Coronary Microvascular Disease
Interventions: DIETARY_SUPPLEMENT: Diet|BEHAVIORAL: Training|DRUG: Medication (with statin and ACE-inhibition)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CART-19 T Cell in CD19 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: CART-19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cost-effectiveness Analysis of Vocal Rehabilitation With Strengthened Tracheoesophageal Voice Implant Prosthesis Versus Standard Voice Prosthesis in Case of Repeated Intra-prosthetic Leakage After Total Laryngectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Laryngectomy
Interventions: DEVICE: Reinforced prosthesis|DEVICE: Standard prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hearing Aids for Veterans With Functional Hearing Difficulties
Status: NOT_YET_RECRUITING
Conditions: Auditory Processing Disorder
Interventions: BEHAVIORAL: Communication Counseling|DEVICE: Hearing Aids|DEVICE: Remote Microphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)
Status: RECRUITING
Conditions: Refractory B-Cell Non-Hodgkin Lymphoma|Refractory B-Cell Small Lymphocytic Lymphoma|Relapsed Adult ALL|Relapsed CLL|Relapsed Non Hodgkin Lymphoma
Interventions: GENETIC: CD19.CAR-aNKT cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Alovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery
Status: RECRUITING
Conditions: Lumbar Spine Disease
Interventions: PROCEDURE: Erector spinae plane block|PROCEDURE: Skin infiltration LA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Medium-chain Fatty Acids on Cardiac Function
Status: NOT_YET_RECRUITING
Conditions: Nutrition, Healthy|Heart Failure
Interventions: DIETARY_SUPPLEMENT: acute intake of medium-chain fatty acids or long-chain fatty acids in patients|DIETARY_SUPPLEMENT: Acute intake of medium-chain fatty acids or long-chain fatty acids in healthy individuals
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurostimulation in Chronic and Episodic Migraine
Status: TERMINATED
Conditions: Double-blind Design|Sham-controlled|Randomized
Interventions: DEVICE: tDCS device from neuroConn
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML)
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndrome|Leukemia, Myelomonocytic, Chronic|Leukemia, Myeloid, Acute
Interventions: DRUG: Azacitidine|DRUG: Pevonedistat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Influenza Vaccine When Administered in Children Who Previously Participated in Study 115345
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix Quadrivalent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Below Study - Balloonangioplasty or Stents With ReoPro for Prevention of Subacute Reocclusion in Arteries Below the Knee
Status: UNKNOWN
Conditions: Patients Above 18 Years
Interventions: DRUG: abciximab|DEVICE: stent and drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Versus Mefloquine Prophylaxis
Status: COMPLETED
Conditions: Malaria|Plasmodium Falciparum
Interventions: DRUG: Chloroquine prophylaxis|DRUG: Mefloquine prophylaxis|BIOLOGICAL: Immunization|BIOLOGICAL: Controlled Human Malaria Infection|DRUG: Malarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EAA Intake to Optimize Protein Anabolism in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Free balanced amino acid mixture|DIETARY_SUPPLEMENT: Free essential amino acid mixture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Evaluate Darbepoetin Alfa in Pediatric Subjects With Anemia Due to Chronic Kidney Disease
Status: WITHDRAWN
Conditions: Anemia|Chronic Kidney Disease
Interventions: DRUG: Darbepoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Hydroxychloroquine Combined With Low-dose Corticosteroid in Pulmonary Sarcoidosis
Status: UNKNOWN
Conditions: Pulmonary Sarcoidosis
Interventions: DRUG: Hydroxychloroquine + low-dose prednisone|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Post-transplant Cyclophosphamide in Pediatric Patients
Status: UNKNOWN
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: OTHER: Drug: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy With Sargramostim (GM-CSF) in Treating Patients With Her-2 Positive Stage III-IV Breast Cancer or Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Breast Cancer|Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor
Interventions: BIOLOGICAL: pNGVL3-hICD vaccine|BIOLOGICAL: sargramostim|OTHER: flow cytometry|OTHER: immunologic technique|OTHER: immunoenzyme technique|GENETIC: protein expression analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danish Vulva Cancer Recurrence Study
Status: NOT_YET_RECRUITING
Conditions: Vulva Cancer|Vulva Neoplasm|Vulvar Cancer|Vulva Disease|Vulvar Neoplasms|Vulvar Diseases|PROM|Circulating Tumor DNA|Survivorship
Interventions: DIAGNOSTIC_TEST: Measurement of circulating tumor-DNA|OTHER: Collection of patient-reported outcomes|OTHER: Algorithmically determined telephone interview with a nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Sildenafil Citrate on Insulin Resistance in African American
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: ROSA Robot Used in Total Knee Replacement Post Market Study
Status: COMPLETED
Conditions: Knee Pain|Chronic Osteoarthritis|Avascular Necrosis of the Femoral Condyle|Moderate Varus, Valgus or Flexion Deformities|Rheumatoid Arthritis
Interventions: DEVICE: PERSONA Total Knee|DEVICE: Vanguard Total Knee|DEVICE: NexGen Total Knee
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Newly Emerging Immunotherapy for Pancreatic Cancer Treatment
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: JS001|DRUG: JS004|DRUG: JS007|DRUG: JS015|DRUG: Irinotecan Liposome Injection|DRUG: 5-Fluorouracil (5-FU)|DRUG: Leucovorin (LV)|DRUG: Nab paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Fraction Real-time High-Dose-Rate Brachytherapy in Patients With Low and Intermediate Risk Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: RADIATION: MRI-TRUS fusion guided Single Frac HDR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed)
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Plus Sargramostim and Interleukin-2 Compared With Nilutamide Alone in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: recombinant fowlpox-prostate specific antigen vaccine|BIOLOGICAL: recombinant vaccinia prostate-specific antigen vaccine|BIOLOGICAL: recombinant vaccinia-B7.1 vaccine|BIOLOGICAL: sargramostim|DRUG: nilutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Status: UNKNOWN
Conditions: Diuretic Abuse
Interventions: DRUG: Furosemid hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Supplemental Docosahexaenoic Acid (DHA) on Neurocognitive Outcomes in Teen and Adult Women With Phenylketonuria(PKU)
Status: COMPLETED
Conditions: Phenylketonuria
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic Acid|DIETARY_SUPPLEMENT: Corn/soy oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Allogeneic Human Dental Pulp Mesenchymal Stem Cells to Treat Severe COVID-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: allogeneic human dental pulp stem cells (BSH BTC & Utooth BTC)|OTHER: Intravenous saline injection (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects
Status: COMPLETED
Conditions: Typhoid Fever
Interventions: BIOLOGICAL: Ty800 (Salmonella typhi) Oral Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Ginseng HRG80 in Stress and Fatigue
Status: COMPLETED
Conditions: Psychological Stress
Interventions: DIETARY_SUPPLEMENT: HRG80 Panax ginseng|DIETARY_SUPPLEMENT: Panax ginseng|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Electrical Stimulation Over Acupuncture Points in Reduction of Rectal Discomfort Distension
Status: COMPLETED
Conditions: Pain
Interventions: DEVICE: Transcutaneous Electrical Nerve Stimulation (ITO Company )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-wave Diathermy in Patients With Osteoarthritis of the Hand
Status: UNKNOWN
Conditions: Hand Osteoarthritis
Interventions: DEVICE: Short-wave diathermy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Conversion Study of Immediate Release (IR) and Modified Release (MR) Forms of Topiramate (TPM)
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Topiramate IR|DRUG: Topiramate ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: DRUG: Imlunestrant|DRUG: Tamoxifen|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Axitinib Therapy of Renal Cell Cancer in High Risk Patients
Status: TERMINATED
Conditions: Clear Cell Renal Carcinoma
Interventions: DRUG: Axitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China
Status: COMPLETED
Conditions: Sepsis|Septic Shock
Interventions: DRUG: ulinastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Delirium Simulation Education of Nurses in Intensive Care Unit
Status: UNKNOWN
Conditions: Self Efficacy|Nursing Caries|Intensive Care Unit Delirium|Simulation of Physical Illness
Interventions: OTHER: education strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Effect of Particle Size of AZD7594 on Pharmacokinetics (PK) After a Single Inhaled Dose When Administered Using the Dry Powder Inhaler in Healthy Volunteers
Status: COMPLETED
Conditions: Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Treatment A - AZD7594|DRUG: Treatment B - AZD7594|DRUG: Treatment C - AZD7594
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MI-CBTech: A Mobile Intervention for Community Integration in Homeless-Experienced Veterans With SMI
Status: RECRUITING
Conditions: Schizophrenia Spectrum Disorders|Psychotic Affective Disorders|Psychotic Mood Disorders|Homelessness|Ill-Housed Persons
Interventions: BEHAVIORAL: MI-CBTech|BEHAVIORAL: Mindfulness control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Erlotinib With or Without Fulvestrant in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Non-inferiority Study on Dose Reduction of Adalimumab in Psoriasis Patients Who Are Overtreated
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Dose tapering of adalimumab in patients with supratheurapeutic serum trough levels|PROCEDURE: Venapuncture|OTHER: Dermatology Life Quality Index (DLQI)|OTHER: EQ-5D-5L questionnaire|PROCEDURE: Dried blood spot sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT