pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Role and Molecular Mechanism of Farnesoid X Receptor(FXR) and RIPK3 in the Formation of Acute Respiratory Distress Syndrome in Neonates
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Acute Lung Injury|FXR|RIPK3
Interventions: OTHER: FXR|OTHER: RIPK3
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Application of Different Techniques of Elastic Bandage
Status: COMPLETED
Conditions: Forearm Muscle Strain
Interventions: DIAGNOSTIC_TEST: Without bandages|DIAGNOSTIC_TEST: With placebo|DIAGNOSTIC_TEST: With bandage|DIAGNOSTIC_TEST: With tensioned bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab in Treating Patients With Hormone Receptor Positive, Localized Inflammatory Breast Cancer Who Are Receiving Hormone Therapy and Did Not Achieve a Pathological Complete Response to Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Breast Inflammatory Carcinoma|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABC
Status: COMPLETED
Conditions: Breast Neoplasms|Carcinoma, Ductal|Adenocarcinoma
Interventions: DEVICE: Active Breathing Coordinator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
Status: RECRUITING
Conditions: Intraabdominal Hypertension|Abdominal Compartment Syndrome|Acute Kidney Injury|Cardiovascular Surgery
Interventions: DEVICE: Accuryn Monitoring System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Acupressure for Fatigue in Systemic Lupus Erythematosus
Status: TERMINATED
Conditions: Fatigue|Lupus Erythematosus, Systemic|Pain, Chronic|Quality of Life|Sleep
Interventions: BEHAVIORAL: Relaxing acupressure plus usual care|BEHAVIORAL: Usual care|BEHAVIORAL: Stimulating acupressure plus usual care|BEHAVIORAL: Sham acupressure plus usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Metabolism in Pregnant Women With a History of Bariatric Surgery, as Well as Three to Six Months After Delivery.
Status: COMPLETED
Conditions: Bariatric Surgery Candidate|Pregnancy Complications|Pregnancy Related|Glucose Metabolism Disorders
Interventions: OTHER: OGTT|OTHER: IVGTT|OTHER: 1H-magnetic resonance spectroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Feasibility and Acceptability of Biofeedback-based Virtual Reality Game for Children
Status: NOT_YET_RECRUITING
Conditions: Pediatric Population
Interventions: OTHER: The biofeedback-assisted VR game "Golden Breath"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tezepelumab and Methacholine Airway Hyperresponsiveness in Participants With Mild Allergic Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma, Allergic
Interventions: DRUG: Tezepelumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensorimotor Affect Relationship-based Therapy (SMART) for Children With Autism Spectrum Disorders Ages 2-12
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Autistic Disorder
Interventions: BEHAVIORAL: Sensorimotor Affect Relationship-based Therapy (SMART)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Test Product Versus Cysteamine 5% in Treatment of Facial Epidermal Melasma
Status: RECRUITING
Conditions: Melasma
Interventions: OTHER: Group TP|DRUG: Group CYS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Nortriptyline and Transdermal Nicotine for Smoking Cessation
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: nortriptyline|DRUG: transdermal nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Spectroscopy to Detect Urothelial Cancer in Urine
Status: UNKNOWN
Conditions: Urothelial Carcinoma|Urinary Bladder Cancer|Urinary Tract Cancer
Interventions: DEVICE: Urinary Multimodal Fiber Optic Spectroscopy|DIAGNOSTIC_TEST: Urine Cytology|PROCEDURE: Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Standard vs High Dose of Unfractionated Heparin in the Incidence of Radial Artery Occlusion (DEFINITION) Trial.
Status: RECRUITING
Conditions: Radial Artery Occlusion
Interventions: DRUG: Unfractionated Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Effectiveness of Kinesio Taping in Patients With Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low-back Pain
Interventions: OTHER: Kinesio taping|DEVICE: Conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: BMS-986142|DRUG: Placebo|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Safety & Efficacy of Autologous Human Platelet Lysate (HPL) in Treatment of Dark Circles
Status: UNKNOWN
Conditions: Periorbital Hyperpigmentation (Dark Circles)
Interventions: OTHER: Autologous Human Platelet Lysate|OTHER: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Dietary Supplementation on Fat Oxidation
Status: RECRUITING
Conditions: Overweight|Obesity
Interventions: DIETARY_SUPPLEMENT: Dietary supplement containing plant derived phenolics|DIETARY_SUPPLEMENT: Microcrystaline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Ovulation Achieved by Single Intra-vaginal Administration of Levogel as Compared to Oral LNG
Status: COMPLETED
Conditions: Female Contraception
Interventions: DRUG: Levonorgestrel (LNG) gel (Levogel) and oral LNG (Plan B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: The Efficacy of Postoperative Application of HFNC at Acute Phase for Minimally Invasive Esophagectomy Surgery Patients
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DEVICE: High flow nasal cannula, HFNC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Evaluation of the Imescard Compound Water Smartweed Ointment
Status: UNKNOWN
Conditions: Hemorrhoidal Disease
Interventions: DRUG: Imescard compound water smartweed ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: EMG Biofeedback Based Pelvic Floor Training in Post Partum Women
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DEVICE: Electromographic Biofeedback|OTHER: PFM exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Immediate Implant Placement in the Molar Regions
Status: COMPLETED
Conditions: Periodontitis|Dental Caries|Periapical Periodontitis
Interventions: PROCEDURE: Use of a membrane to cover bonedefects around implant|DEVICE: Use of bonechips to fill up defects around implant|PROCEDURE: Use of membrane and bonechips to manage defects
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Pharmacodynamics of BIOD-961 vs. Marketed Glucagons
Status: COMPLETED
Conditions: Hypoglycemia
Interventions: DRUG: BIOD-961|DRUG: Lilly Glucagon|DRUG: Novo Glucagon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Dialogue Circles" to Reduce the Level of Caregiver Overload in Complex Chronic Patients and Advanced Chronic Disease
Status: UNKNOWN
Conditions: Caregiver Burnout
Interventions: OTHER: Dialog Circle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tethered Capsule Endoscope in Screening Patients With Barrett Esophagus
Status: COMPLETED
Conditions: Barrett Esophagus
Interventions: OTHER: Survey Administration|DEVICE: Tethered Capsule Endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Fludarabine With or Without Cyclophosphamide in Treating Patients With Advanced Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: Fludarabine plus Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Thrombus Aspiration in Patients With Myocardial Infarction Presenting Late After Symptom Onset
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DEVICE: manual thrombus aspiration (Export catheter, Medtronic Inc. Minneapolis, Minnesota, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Niraparib in High-grade Endometrial Cancer Trial
Status: NOT_YET_RECRUITING
Conditions: Endometrial Cancer|Serous Adenocarcinoma|Uterine Neoplasm
Interventions: DRUG: Niraparib oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial of IMO-3100 in Patients With Moderate to Severe Plaque Psoriasis
Status: COMPLETED
Conditions: Actively Extending Plaque Psoriasis|Moderate to Severe Plaque Psoriasis
Interventions: DRUG: IMO-3100 at 0.16 mg/kg|DRUG: Saline for Injection|DRUG: IMO-3100 at 0.32 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interest of the 18F-DOPA-PET Imaging in Metastatic Melanoma Treated With B-RAF Inhibitors: a Pilot Study
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DEVICE: PET with 18F-FDOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ipilimumab or FOLFOX in Combination With Nivolumab and Trastuzumab in HER2 Positive EsophagoGastric Adenocarcinoma
Status: COMPLETED
Conditions: Gastric Cancer|Esophageal Cancer|Adenocarcinoma Gastric|HER2 Positive Gastric Cancer|Metastatic Gastric Cancer|GastroEsophageal Cancer
Interventions: DRUG: Nivolumab|DRUG: Nivolumab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closing the Loop in Children and Adolescents With Type 1 Diabetes in the Home Setting
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Endocrine System Diseases|Autoimmune Diseases
Interventions: DEVICE: Overnight closed-loop|DEVICE: Real-time CGM alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Xeloda (Capecitabine) Plus Radiation Therapy in Children With Newly Diagnosed Gliomas
Status: COMPLETED
Conditions: Glioma
Interventions: DRUG: capecitabine [Xeloda]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasonographic Axillary Localization
Status: UNKNOWN
Conditions: Breast Neoplasm
Interventions: DIAGNOSTIC_TEST: Ultrasonographical tattooing of suspicious axillary lymph nodes.|PROCEDURE: Sentinel lymph node biopsy|DIAGNOSTIC_TEST: Histopathological examination of the axillary nodes|PROCEDURE: Further axillary management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Antimalaria Drugs Susceptibility Testing for an Effective Management of Infected Patients in Sub-Sahara Africa
Status: COMPLETED
Conditions: Drug Resistant Malaria Due to Plasmodium Falciparum
Interventions: DRUG: Arthemeter-lumefantrine|DRUG: Artesunate mefloquine|DRUG: Dihydroartemisinin piperaquine|DRUG: Paracetamol|DRUG: Amoxicillin|DRUG: Quinine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine
Status: COMPLETED
Conditions: Chordoma|Chondrosarcoma
Interventions: RADIATION: Charged Particle Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety & Efficacy of Budesonide Inhalation Suspension in Japanese Children With Bronchial Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Pulmicort (budesonide) Respules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viscoelastic Tests-Guided Therapy In Liver Transplantation
Status: COMPLETED
Conditions: Liver Transplant; Complications|Bleeding|Hemostatic Disorder
Interventions: OTHER: Usual Care|OTHER: Thromboelastometry-Guided Therapy with Synthetic Factor Concentrates
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deprescribing Tamsulosin in Older Men
Status: UNKNOWN
Conditions: Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: Tamsulosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Lower-concentration Dysport Treatment Targeted to the Neuromuscular Junction With Current Clinical Practice
Status: TERMINATED
Conditions: Arm Spasticity
Interventions: BIOLOGICAL: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single and Multiple Dose Pharmacokinetic Study of 90 mg and 180 mg Doses of AZD6140 in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: AZD6140|DRUG: AZD6140
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Congestive Heart Failure Home Telemonitoring
Status: WITHDRAWN
Conditions: Heart Failure|Blood Pressure|Body Weight
Interventions: DEVICE: Weight and blood pressure device|DEVICE: Home telemonitoring device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness
Status: COMPLETED
Conditions: Dry Eye
Interventions: DEVICE: DM05 eye drops|DEVICE: Optive™ eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Network Analysis of Intracranial Stereoelectroencephalography
Status: UNKNOWN
Conditions: Epilepsy in Children|Focal Epilepsy|Epilepsy Intractable|Epilepsy, Focal|Intractable Epilepsy|Refractory Epilepsy|Epilepsies, Partial
Interventions: PROCEDURE: Combined Micro-Macro SEEG Electrodes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neoadjuvant Study Investigating Degarelix in Patients Suffering From Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Degarelix|DRUG: Goserelin|DRUG: Bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Prehabilitation for Lung Cancer Surgery
Status: RECRUITING
Conditions: Lung Cancer|Surgery
Interventions: DIETARY_SUPPLEMENT: Mixed-nutriend supplement (NUT)|OTHER: Multimodal Prehabilitation (MM)|DIETARY_SUPPLEMENT: Placebo Control (CTRL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Bunsimgieum on the Chest Discomfort of Hwa-byung's Major Symptom
Status: COMPLETED
Conditions: Hwa-byung (Disorder)
Interventions: DRUG: mild-ex-gwarip|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Dendritic Cytotoxic Lymphocyte(DC-CTL) Cell Infusion in NSCLC Patients
Status: UNKNOWN
Conditions: NSCLC
Interventions: DRUG: gemcitabine|BIOLOGICAL: DC-CTL|DRUG: cisplatinum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improve New Learning and Memory in Individuals With Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Memory Retraining Exercises|BEHAVIORAL: Placebo Control Memory Exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SurgiFill™ on Spinal Fusion
Status: UNKNOWN
Conditions: Spinal Fusion Acquired|Fusion of Spine (Disease)
Interventions: PROCEDURE: Spinal Fusion|DEVICE: SurgiFill™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Powdered Fermented Fruits for Glycemia Reduction
Status: UNKNOWN
Conditions: Cardiometabolic Risk Factors|Obesity, Abdominal
Interventions: OTHER: Fermented orange flour|OTHER: Fermented grape flour|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle
Interventions: DEVICE: OMNI® Surgical System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug Interaction Between Ritonavir And Sitaxsentan
Status: WITHDRAWN
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Sitaxentan|DRUG: Ritonavir|DRUG: Sitaxsentan|DRUG: Ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase 1 LEISH-F3 Vaccine Trial in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Leishmaniasis
Interventions: BIOLOGICAL: LEISH-F3 + GLA-SE|BIOLOGICAL: LEISH-F3 + GLA-SE|BIOLOGICAL: LEISH-F3 alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer
Status: RECRUITING
Conditions: Head and Neck Cancer
Interventions: DRUG: DEFINITY|DEVICE: Sonalleve Focused Ultrasound Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Evaluation of Systane® Gel Drops in Dry Eye Subjects
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: Polyethylene Glycol, 0.4%, Propylene Glycol, 0.3% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome
Status: COMPLETED
Conditions: Kidney Cancer|Von Hippel-lindau Syndrome
Interventions: GENETIC: mutation analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)
Status: RECRUITING
Conditions: ccRCC|Clear Cell Renal Cell Carcinoma|Kidney Cancer|Kidney Neoplasms|Renal Cancer|Renal Neoplasms|Recurrent Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma|Refractory Renal Cell Carcinoma|Advanced Renal Cell Carcinoma|Carcinoma|Neoplasms|Carcinoma, Renal Cell|Neoplasms, Glandular and Epithelial|Neoplasm by Histology|Adenocarcinoma|Urologic Neoplasms|Urogenital Neoplasms|Neoplasms by Site|Kidney Diseases|Urologic Diseases
Interventions: DRUG: NKT2152|DRUG: palbociclib|OTHER: sasanlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amifostine in Treating Patients With Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Amifostine Trihydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating the Efficacy of Pediatric Lipid Screening Alerts
Status: COMPLETED
Conditions: Hypercholesterolemia|Hypercholesterolemia, Familial|Hypercholesteremia in Children|Hyperlipidemia in Children
Interventions: BEHAVIORAL: Best Practice Alert|BEHAVIORAL: Health Maintenance Topic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SCREENING
Clinical trial: Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects
Status: RECRUITING
Conditions: Common Cold|Nasal Congestion
Interventions: DEVICE: IP1 - Stérimar BLOCKED NOSE Baby nasal spray|DEVICE: IP2 - Stérimar Stop & Protect Cold Baby + standard of care|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THE EFFECT OF WEB-BASED BREASTFEEDING COUNSELING
Status: COMPLETED
Conditions: Web-based Breastfeeding Counseling
Interventions: OTHER: The web-based breastfeeding counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study on the Treatment of Hypertensive Intracerebral Hemorrhage With Panax Notoginseng Saponin
Status: COMPLETED
Conditions: Hematoma Absorption and Neurological Function Recovery
Interventions: DRUG: Panax Notoginseng Saponins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Estimate The Effect Of Lersivirine On The Pharmacokinetics Of S- And R-Methadone
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Methadone|DRUG: Lersivirine + Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnoea and Cardiac Arrhythmias
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea|Cardiovascular Diseases|Arrhythmia|Atrial Fibrillation New Onset
Interventions: DEVICE: Reveal LINQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Kidney Problems
Status: COMPLETED
Conditions: Renal Insufficiency|Healthy
Interventions: DRUG: BI 1015550
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Percutaneous Coronary Intervention Versus Medical Treatment for Stable Angina Pectoris
Status: UNKNOWN
Conditions: Coronary Heart Disease|Stable Angina|Ischemic Heart Disease
Interventions: PROCEDURE: Percutaneous Coronary Intervention|PROCEDURE: Sham-percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interleukin-1 Blockade in HF With Preserved EF
Status: COMPLETED
Conditions: Heart Failure With Normal Ejection Fraction
Interventions: DRUG: Anakinra|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a Dietary Supplement on Lipid Pattern, Indexes of NAFLD and Systemic Inflammation in Healthy Subjects With Suboptimal LDL-C Levels
Status: NOT_YET_RECRUITING
Conditions: Hypercholesterolemia|Inflammation
Interventions: DIETARY_SUPPLEMENT: Dietary supplement formulated with components of natural origin: artichoke, danshen, bergamot, folic acid, chromium and excipients.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Versus Simultaneous Use of Vinorelbine and Capecitabine in Patients With Metastatic Breast Cancer (MBC)
Status: COMPLETED
Conditions: Breast Cancer|Metastasis, Neoplasm
Interventions: DRUG: Vinorelbine and Capecitabine|DRUG: Vinorelbine and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 12-week Efficacy of Indacaterol
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol 75 μg|DRUG: Placebo to indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose, Pharmacokinetic, Safety, Tolerability and QTc Study of GSK1278863 in Healthy Volunteers
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: GSK1278863 75 mg|DRUG: GSK1278863 500 mg|DRUG: Moxifloxacin 400 mg|DRUG: Placebo matching GSK1278863|DRUG: Placebo matching Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: People Living With HIV/AIDS, Nitrate, Endotelial Function, Arterial Stiffness and Skeletal Muscle Oxygenation
Status: COMPLETED
Conditions: HIV/AIDS
Interventions: DIETARY_SUPPLEMENT: Beetroot Juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448)
Status: COMPLETED
Conditions: Cancer of the Breast|Breast Cancer|Advanced Breast Cancer|Metastatic Breast Cancer|Male Breast Cancer|Triple Negative Breast Cancer|ER+ Breast Cancer
Interventions: DRUG: Seviteronel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Treadmill Based Aerobic Exercise Intervention On Menstruation And Quality Of Life In Women With Polycystic Ovarian Syndrome
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome|Irregular Menses
Interventions: DEVICE: Treadmill exercise|OTHER: low caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point of Care Tests for Syphilis and HIV
Status: COMPLETED
Conditions: Syphilis
Interventions: DEVICE: INSTI Multiplex HIV-1/2 Syphilis AB test|DEVICE: Multiplo Rapid TP/HIV test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pneumoperitoneum Management With SurgiQuest AirSeal at Low vs. Higher Pressure ( PRESSURE )
Status: COMPLETED
Conditions: Shoulder Pain
Interventions: DEVICE: SurgiQuest AIRSEAL® Insufflation System (AIS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation + Cisplatin or Panitumumab in Locally Advanced Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: panitumumab|DRUG: cisplatin|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: accelerated radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus (FK506) Study in Moderate to Severe Refractory Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma (LyMIC)
Status: RECRUITING
Conditions: Cholangiocarcinoma|Cholangiocarcinoma, Intrahepatic|Cholangiocarcinoma Resectable|Cholangiocarcinoma; Liver
Interventions: DIAGNOSTIC_TEST: LyMIC (Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of Robot-assisted Early Mobilization - Project MobiStaR
Status: COMPLETED
Conditions: Patient Activation|Mobilization|Robotics
Interventions: DEVICE: VEMO (Reactive Robotics GmbH)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Nanoparticle-incorporated Bonding Agent on Post-restorative Sensitivity
Status: COMPLETED
Conditions: Carious Lesion
Interventions: PROCEDURE: Composite resin restoration using Titania nanoparticle reinforced bonding agent|PROCEDURE: Composite resin restoration without Titania nanoparticle incorporated bonding agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Paricalcitol in Chronic Hemodialysis Patients
Status: UNKNOWN
Conditions: Endstage Renal Disease|Secondary Hyperparathyroidism
Interventions: DRUG: Intravenous Paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FORWARD Optune and Adjuvant TMZ in Grade II/III Astrocytoma
Status: TERMINATED
Conditions: Astrocytoma, Grade II|Astrocytoma, Grade III
Interventions: COMBINATION_PRODUCT: TTFields with adjuvant temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: METabolic PROFILE of Hepatocarcinoma and Pancreatic Tumors
Status: RECRUITING
Conditions: Hepatocarcinoma|Pancreatic Tumor
Interventions: BIOLOGICAL: Hepatocellular carcinoma|BIOLOGICAL: Pancreatic adenocarcinoma|BIOLOGICAL: Pancreatic neuroendocrine tumor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genistein, Gemcitabine, and Erlotinib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DIETARY_SUPPLEMENT: genistein|DRUG: erlotinib hydrochloride|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy and Safety of Remifentanil in a Rapid Sequence Induction for Fragile Subjects
Status: COMPLETED
Conditions: Tachycardia
Interventions: DRUG: 0.5 µg/kg remifentanil|DRUG: 1.0 µg/kg remifentanil|DRUG: NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: epoetin alfa|BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Peritoneal Irrigation at Elective Cesarean Section
Status: UNKNOWN
Conditions: Postoperative Recovery
Interventions: PROCEDURE: Elective Cesarean Section|OTHER: Peritoneal irrigation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sleeve-pex: A Randomized Trial to Reduce Reflux After Sleeve Gastrectomy
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal Reflux
Interventions: PROCEDURE: Sleeve gastrectomy with gastropexy|PROCEDURE: Sleeve gastrectomy without gastropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: A Study of Injections of LY3074828 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3074828|DEVICE: Pre-filled syringe (PFS)|DEVICE: Autoinjector (AI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)- Cardiovascular Endpoints
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tofacitinib|DRUG: TNF Inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessing the Efficacy of Needling With or Without Corticosteroids in the Repigmentation of Vitiligo
Status: TERMINATED
Conditions: Vitiligo
Interventions: PROCEDURE: Needling|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Causes of Visual Impairment Among Patients Applying for the Visually Disability Certification
Status: ACTIVE_NOT_RECRUITING
Conditions: Visual Impairment
Interventions: DIAGNOSTIC_TEST: 1- uncorrected and best corrected visual acuity (UCVA and BCVA) by Snellen's-chart.2-slit lamp bio microscopy (Haag-Streit, USA).3-IOP measurements (Goldmann Applanation tonometer)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiological and Biological Tumoural and Peri-tumoural Factors in Neoadjuvant Endocrine-treated Breast Cancers
Status: COMPLETED
Conditions: Breast Cancer
Interventions: OTHER: Shearwave elastography|DRUG: Letrozole|PROCEDURE: Breast core biopsy|OTHER: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan
Status: COMPLETED
Conditions: Liver Disease
Interventions: DRUG: conivaptan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Determinants of Smoking Cessation Among Latinos
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Nicotine Replacement Therapy (NRT)|BEHAVIORAL: Questionnaire|BEHAVIORAL: Counseling|BEHAVIORAL: Self-Help Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rotator Cuff Tendinopathy Conservative Treatment With Collagen, PRP or Both
Status: UNKNOWN
Conditions: Rotator Cuff Tendinosis|Rotator Cuff Tears
Interventions: COMBINATION_PRODUCT: Collagen and platelet rich plasma (PRP)|COMBINATION_PRODUCT: Collagen|COMBINATION_PRODUCT: Platelet rich plasma (PRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Between Robotic and Open Surgery in Patients With Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Minimally Invasive Surgery
Interventions: PROCEDURE: robotic surgery|PROCEDURE: open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Metformin in Treatment of Childhood Obesity
Status: COMPLETED
Conditions: Pediatric Obesity
Interventions: DRUG: Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Decrease Length of Stay in Infants With Neonatal Abstinence Syndrome With an Exclusive Human Milk Diet
Status: RECRUITING
Conditions: Neonatal Abstinence Syndrome
Interventions: OTHER: Human Milk|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy
Status: COMPLETED
Conditions: Chemotherapeutic Agent Toxicity|Neurotoxicity|Pain|Peripheral Neuropathy|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: OTHER: questionnaire administration|OTHER: Sensory Neuropathy Scale instrument|OTHER: Quality of Life instrument|DEVICE: MC5-A Scrambler device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Almond Intake on Atherogenic Lipoprotein Particles
Status: COMPLETED
Conditions: Dyslipidemia|Obesity, Abdominal
Interventions: OTHER: Standard reference diet|OTHER: Almond supplemented diet|OTHER: Low carbohydrate reference diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yamani Technique Versus Proline Mesh for Intraocular Lens Scleral Fixation in Aphakia
Status: RECRUITING
Conditions: Aphakia, Postcataract
Interventions: PROCEDURE: Yamani Technique versus Prolene Mesh for Intraocular Lens Scleral Fixation in Aphakia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Therapy and Kinetics of Inflammatory Markers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: kINESIOTAPING ON PATIENT'S FUNCTIONAL STATUS IN NON-SPECIFIC NECK PAIN
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Kinesiotaping group|OTHER: stretching group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Celecoxib in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer
Status: TERMINATED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: celecoxib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Challenge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GZR4 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: GZR4|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder
Status: TERMINATED
Conditions: Carcinoma in Situ of Bladder|Bladder Cancer
Interventions: DRUG: Durvalumab|PROCEDURE: Cystoscopy with Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas
Status: RECRUITING
Conditions: Central Nervous System Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Isavuconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Repetitive Transcranial Magnetic Stimulation in Bipolar Patients
Status: COMPLETED
Conditions: Cognitive Impairment|Relapse|Bipolar Disorder
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Gait in Persons With Knee Related Mobility Limitations by Rosenoids® Food Supplement: a Randomized Double-blind Placebo-controlled Trial
Status: COMPLETED
Conditions: Knee Related Walking Limitations
Interventions: DIETARY_SUPPLEMENT: Rosehip|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CONFIDENCE Financial Education for Caregivers
Status: COMPLETED
Conditions: Caregiver Burden|Financial Stress|Dementia|Alzheimer Disease
Interventions: BEHAVIORAL: Confidently Navigating Financial Decisions and Enhancing Financial Wellbeing in Dementia Caregiving
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term Radiological and Clinical Outcomes of Fixation of Schatzker II Tibial Plateau Fractures by Screws Only Versus Plate and Screws , Comparative Study
Status: RECRUITING
Conditions: Tibial Plateau Fractures Schatzker Type II
Interventions: PROCEDURE: fixation of tibial plateau fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-Based Treatment for Children With Traumatic Brain Injuries & Their Families: Counselor Assisted Problem Solving
Status: COMPLETED
Conditions: Traumatic Brain Injury
Interventions: BEHAVIORAL: Counselor-assisted problem solving (CAPS)|BEHAVIORAL: Internet-resource comparison (IRC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Focused Transthoracic Echocardiography in Urgent Abdominal Surgery for Septic Patients
Status: COMPLETED
Conditions: Sepsis|Hypovolemia|Peritonitis
Interventions: OTHER: Focused assessed echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT