pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Determining the Feasibility of Implementing a Combined Cognitive and Exercise Training Program for Older Adults in a Community Setting.
Status: COMPLETED
Conditions: Osteo Arthritis|Osteoporosis|Joint Replacement|Fibromyalgia|High Blood Pressure|Stable Heart Conditions|Chronic Obstructive Pulmonary Disease|Diabetes|Obesity
Interventions: OTHER: Exercise and Cognitive Training|OTHER: Exercise Training Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of Compression Therapy in Patients With Mild to Moderate PAD or Diabetes Mellitus
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Diabetes Mellitus|Leg Edema
Interventions: DEVICE: Compression Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP)
Status: COMPLETED
Conditions: Chronic Ocular Pain
Interventions: OTHER: SAF312 Placebo|DRUG: SAF312
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Hemoporfin PDT in Children(2-7 Years Old) With Port-wine Stain
Status: COMPLETED
Conditions: Port-wine Stain
Interventions: DRUG: Hemoporfin PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endocardial Stem Cells Approach Efficacy
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: PROCEDURE: Autologous bone marrow mononuclear stem cells or peripheral blood stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a New Iloperidone Titration Scheme in Bipolar I Disorder or Schizophrenia
Status: COMPLETED
Conditions: Bipolar I Disorder|Schizophrenia
Interventions: DRUG: Iloperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation
Status: COMPLETED
Conditions: Heart Transplantation
Interventions: DRUG: prednisolon|DRUG: Mycophenolatmofetile|DRUG: Cyclosporin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Kinesio Taping Effect on Pain and Edema in Patients Who Underwent Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Replacement, Total Hip
Interventions: DEVICE: Kinesiotaping|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sequential Tegafur-gimeracil-oteracil Potassium Capsule (s-1) and Serplulimab Following Concurrent Chemoradiotherapy for Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Locally Advanced Inoperable Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Serplulimab|DRUG: Tegafur-gimeracil-oteracil potassium capsule(S1)|RADIATION: Radiotherapy|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combining Lesinurad With Allopurinol in Inadequate Responders
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Lesinurad|DRUG: Lesinurad|DRUG: Placebo|DRUG: Allopurinol|DRUG: Allopurinol|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Innovative Nutrition and mHealth Evidence Building Project
Status: COMPLETED
Conditions: Underweight Children Aged 6-23 Month Old (WAZ < -1)
Interventions: OTHER: Group 1 5+5+5 (Control)|BEHAVIORAL: Group 2: 5+5+5 & PDH|BEHAVIORAL: Group 3: 5+5+5 & PDH lite+mHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase IV Trial,The Efficacy and Safety Study of Fuganlin Oral Liquid in Children With Acute Upper Respiratory Infection
Status: COMPLETED
Conditions: Acute Upper Respiratory Infection
Interventions: DRUG: Low-dose of Fuganlin Oral Liquid|DRUG: High-dose of Fuganlin Oral Liquid
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Long-term Release of Fluoride Formed on Enamel by Fluoride Gel or Varnish to Biofilm Fluid
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: 5% sodium fluoride varnish|DRUG: 1.23% sodium fluoride acidic gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetics of RLX030 in Subjects With Mild, Moderate and Severe Hepatic Impairment Compared to Healthy Subjects
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: RLX030A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Enteroscopy Stiffening Device for Retrograde Balloon Assisted Enteroscopy
Status: TERMINATED
Conditions: Small Bowel Diseases
Interventions: DEVICE: Stiffening wire|DEVICE: Placebo wire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Cetirizine Chewable Bioequivalence and Food Effect Study
Status: COMPLETED
Conditions: Allergy
Interventions: DRUG: Cetirizine 10mg|DRUG: Cetirizine 10 mg|DRUG: Cetirizine 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Double-Blind Single-Ascending Dose (SAD) and Multiple-Ascending Dose (MAD) Study to Investigate the Safety, Tolerability, and Pharmacokinetics of RO7049389 in Healthy Chinese Participants
Status: COMPLETED
Conditions: Hepatitis B Virus
Interventions: DRUG: RO7049389|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study
Status: WITHDRAWN
Conditions: Treatment Resistant Major Depressive Disorder
Interventions: BEHAVIORAL: Almond Therapy|DRUG: Intranasal ketamine (Esketamine)|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a Positive Psychology-based Intervention for Couples Coping With Stroke
Status: COMPLETED
Conditions: Stroke|Depression|Depressive Symptoms|Post-stroke Depression
Interventions: BEHAVIORAL: Dyadic (couples-based) positive psychology intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Presurgical Orthodontic Molding on the Growth of Newborns With Unilateral Cleft Lip Palate
Status: RECRUITING
Conditions: Cleft Lip and Palate|Unilateral Cleft Lip
Interventions: PROCEDURE: passive Alveolar Molding|PROCEDURE: Nasoalveolar Molding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ICG vs Blue Patent as a Tracer in the Performance of TAD in Patients With cN1 Breast Carcinoma After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Breast Cancer|Axillary Metastases
Interventions: PROCEDURE: Targeted axillary dissection (TAD) by ICG|PROCEDURE: Targeted axillary dissection (TAD) by Blue patent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Immunogenicity of a Single Dose of GSK Biologicals' Boostrix™ in Infants Prior to Primary Pertussis Vaccination, When Administered to Pregnant Women as Per Routine Practice in Bogota, Colombia
Status: TERMINATED
Conditions: Diphtheria-Tetanus-Acellular Pertussis
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing Two Palliative Schemes of Radiotherapy for Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Neoplasms
Interventions: RADIATION: 6 x 6 Gy|RADIATION: 16 x 3.125 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of Oral ABBV-744 Tablet Alone or in Combination With Oral Ruxolitinib Tablet or Oral Navitoclax Tablet in Adult Participants With Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis (MF)
Interventions: DRUG: ABBV-744|DRUG: Navitoclax|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to See if Tolvaptan is Safe in Infants and Children Who at Enrollment Are 28 Days to Less Than 18 Years Old With Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Status: RECRUITING
Conditions: Autosomal Recessive Polycystic Kidney (ARPKD)
Interventions: DRUG: Tolvaptan Suspension|DRUG: Tolvaptan Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of RGX-314 (Investigational Product) Gene Therapy for Neovascular AMD Trial
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration|Wet Age-related Macular Degeneration
Interventions: GENETIC: RGX-314
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predicted Level of General Anaesthesia in Hip Fracture Surgery
Status: COMPLETED
Conditions: Hip Fracture Surgery
Interventions: DEVICE: General anesthesia managed by the Smartpilot® View|DEVICE: General anesthesia managed without the Smartpilot® View
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Berry Components and Blood Sugar & Fat Metabolism
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Mixed Berry Diet|OTHER: Carbohydrate Control Jello|OTHER: Fiber Enriched Jello|OTHER: Low Fiber Mixed Berry Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Fentanyl Transdermal System (JNJ-35685-AAA-G021) Compared With DURAGESIC Fentanyl Transdermal Patch in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Fentanyl|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home-based Transcranial Direct Current Stimulation (tDCS) to Promote Social Communication and Behaviour in Children With Autism Spectrum Disorder (ASD)
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DEVICE: At-home transcranial direct current stimulation (tDCS)|DEVICE: Sham at-home tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Spironolactone on Acute Kidney Injury in Critically Ill Patients
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: Spironolactone 25 mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Prevention of Hypertension in Obese Adolescents
Status: COMPLETED
Conditions: Obesity|Pre-Hypertension|Hyperuricemia
Interventions: DRUG: Allopurinol|DRUG: Probenecid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of an Early Change of a Chemotherapeutic Doublet Versus Four Cycles of Chemotherapy in Advanced Non Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Carcinoma
Interventions: DRUG: cisplatin|DRUG: Gemcitabine|DRUG: Taxol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis
Status: RECRUITING
Conditions: Single-ventricle|Pulmonary Vascular Resistance Abnormality|Superior Cavo-Pulmonary Anastomosis|Endothelin|Metabolomics
Interventions: OTHER: Research Blood Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of a Commercial Dentifrice Containing Ilex Rotunda Thunb Extract for Dental Plaque and Gingivitis
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DRUG: Dentifrice Containing Ilex Rotunda Thunb|DRUG: Control dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Combination Chemotherapy With or Without Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed By Surgery
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: cisplatin|DRUG: fluorouracil|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Use of Galantamine (Reminyl ER) in Patients With MIXed Dementia: Effects on Cognition and Quality of Life
Status: COMPLETED
Conditions: Dementia
Interventions: DRUG: Galantamine|DRUG: Nimodipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bilateral Pallidal Stimulation in Patients With Advanced Parkinson's Disease-LATESTIM
Status: TERMINATED
Conditions: Central Nervous System Disease|Basal Ganglia Disease|Movement Disorders|Neurodegenerative Disorders|Parkinson Disease
Interventions: PROCEDURE: Deep brain stimulation (DBS) of Globus Pallidus internus (GPi) and Best medical treatment (BMT)|PROCEDURE: Best medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: sNIPPV Versus NIV-NAVA in Extremely Premature Infants
Status: COMPLETED
Conditions: Premature Birth|Ventilator Lung; Newborn
Interventions: DEVICE: VNI-NAVA/sNIPPV|DEVICE: sNIPPV/VNI-NAVA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bexarotene in Preventing Breast Cancer in Patients at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Atypical Ductal Hyperplasia|Breast Atypical Lobular Hyperplasia|Breast Ductal Carcinoma In Situ|Breast Lobular Carcinoma In Situ|Invasive Breast Carcinoma
Interventions: DRUG: Bexarotene|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Opioid Based Analgesia vs Non-opioid Analgesia for Oocyte Retrieval Procedure
Status: COMPLETED
Conditions: Women Undergoing Oocyte Retrieval Procedures
Interventions: DRUG: IV acetaminophen|DRUG: IV fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome
Status: COMPLETED
Conditions: Dry Eye Syndrome|Keratoconjunctivitis Sicca
Interventions: DEVICE: Oculeve Intranasal|DEVICE: Sham|DEVICE: Oculeve Extranasal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Minocycline for Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: minocycline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lanreotide Autogel Treatment of Patients With Congenital Hyperinsulinism of Infancy
Status: COMPLETED
Conditions: Congenital Hyperinsulinism
Interventions: DRUG: Lanreotide autogel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Determine the Effectiveness of Reaming in Reducing Fat Emboli to the Lungs
Status: COMPLETED
Conditions: Diaphyseal Femur Fracture
Interventions: PROCEDURE: Transesophageal transducer|PROCEDURE: echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Weight Loss Intervention Versus Usual Care for Adults With Severe and Complex Obesity
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Intensive weight loss intervention|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Treatment of Post-hemorrhagic Ventricular Dilation in Preterm Infants
Status: COMPLETED
Conditions: Intraventricular Hemorrhage|Hydrocephalus
Interventions: PROCEDURE: Removal of CSF through ventricular access device|PROCEDURE: Removal of CSF through a ventricular access device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency
Status: RECRUITING
Conditions: Heart Failure|Levosimendan|Milrinone|Efficacy|Safety
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Bleomycin in the Sclerotherapy of Lymphatic Malformations for Pediatric Patients
Status: RECRUITING
Conditions: Lymphatic Malformation
Interventions: DRUG: Bleomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Bisoprolol on Progression of Aortic Stenosis
Status: TERMINATED
Conditions: Aortic Stenosis
Interventions: DRUG: bisoprolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Engineer-Built System, Video-Game Based Kinect Sensor in Upper Extremities Problems in Cerebral Palsy Children
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: DEVICE: The engineer-built system, video-game based Kinect sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiparametric Imaging-based Intraoperative Navigation for Guidance of Surgical Resection and Postoperative Radiotherapy in Patients With Head-and-neck Tumors
Status: RECRUITING
Conditions: Head and Neck Tumors
Interventions: OTHER: intraoperative navigation and creation of tumor resection maps
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab As Consolidation Therapy After Radical Concurrent Chemoradiotherapy In Locally Advanced ESCC
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: DRUG: Camrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ASCT After a Rituximab/Ibrutinib/Ara-c Containing iNduction in Generalized Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: R-CHOP/R-DHAP|DRUG: Ibrutinib (Induction)|DRUG: ASCT conditioning|DRUG: Ibrutinib (Maintenance)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Initiation of Post Sternotomy CArdiac Rehabilitation
Status: COMPLETED
Conditions: Coronary Artery Disease|Aortic Valve Disease|Mitral Valve Disease
Interventions: BEHAVIORAL: timing of initiation of cardiac rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Psychosocial Support for Postoperative Recovery and Health: Mechanistic Substudy
Status: COMPLETED
Conditions: Pain, Acute|Pain, Joint|Pain
Interventions: BEHAVIORAL: Mindfulness of Breath|BEHAVIORAL: Mindfulness of Pain|BEHAVIORAL: Cognitive-Behaviorally Based Pain Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Value of Left Atrial Appendage Flow for Prediction of Successful Catheter Ablation for Persistent Atrial Fibrillation
Status: TERMINATED
Conditions: Persistent Atrial Fibrillation|Catheter Ablation
Interventions: OTHER: a complete transesophageal echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Non Alcoholic Steatohepatitis
Interventions: DRUG: Idebenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Fascia Iliaca Blockade vs Extracapsular Local Field Infiltration With Liposomal Bupivacaine
Status: COMPLETED
Conditions: Femoro Acetabular Impingement
Interventions: DRUG: liposomal bupivicaine|PROCEDURE: Fascia iliaca blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rivaroxaban Combined With DAPT Versus DAPT Alone After Drug-coated Balloon Angioplasty
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality to Alleviate Claustrophobia During MRI
Status: COMPLETED
Conditions: Claustrophobia
Interventions: DEVICE: Immersion in virtual reality using Nordic Neurolab(™) Visual System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Postural Correction On Gastroesophageal Reflux Disease
Status: RECRUITING
Conditions: Gastro Esophageal Reflux|Gastro Esophageal Reflux Disease
Interventions: OTHER: Spinal Strengthening Exercises|OTHER: Thoracic Spine Stretching|OTHER: Thoracic Spine Mobilization|OTHER: Sham Postural Correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of Liposomal Encapsulation on Calcium Powder Absorption and Metabolism
Status: RECRUITING
Conditions: Osteoporosis
Interventions: DIETARY_SUPPLEMENT: Stage 1|DIETARY_SUPPLEMENT: Stage 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study of Alisertib (MLN8237) in Adult East Asian Participants With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphomas
Interventions: DRUG: Alisertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Promoting Physical Activity In After-School Programs for Urban Adolescents
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BEHAVIORAL: exercise intervention|OTHER: counseling intervention|OTHER: educational intervention|PROCEDURE: complementary or alternative medicine procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Navigation for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC
Status: COMPLETED
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: BEHAVIORAL: NDURE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Intracavernous Injection of Botox 100 U for Treatment of PDE5Is Inconvenient Patients With ED
Status: UNKNOWN
Conditions: Erectile Dysfunction
Interventions: BIOLOGICAL: OnabotulinumtoxinA|DRUG: Trimix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Leukocyte Antigen-A*2402-Restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer|Pancreas Neoplasms
Interventions: BIOLOGICAL: VEGFR1-A24-1084 (SYGVLLWEI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Episodic Breathlessness in Patients With Lung Cancer or Other Advanced Disease
Status: COMPLETED
Conditions: Dyspnea|Lung Cancer|Metastatic Cancer
Interventions: OTHER: medical chart review|OTHER: study of socioeconomic and demographic variables|OTHER: survey administration|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AeriSeal System for Lung Volume Reduction
Status: COMPLETED
Conditions: Emphysema|Chronic Obstructive Pulmonary Disease (COPD)|Pulmonary Emphysema|Lung Diseases
Interventions: DEVICE: AeriSeal System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Optimization for Stroke Evaluation
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Disorders|Brain Ischemia|Infarction
Interventions: BEHAVIORAL: Accelerated Skill Acquisition Program (ASAP)|BEHAVIORAL: Active Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-Term Safety and Tolerability of GK Activator (2) in Patients With Type 2 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: GK Activator (2)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Genicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Role of Peptide-loaded Dendritic Cells to Augment the Therapeutic Effect of Interleukin-2
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: PROCEDURE: Immunotherapy treatment for melanoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of Fiber Reinforced FRC Base and Bonded CAD/CAM Resin Composite Endocrowns Versus Conventional Lithium Disilicate Endocrowns in Posterior Teeth (1y Randomized Clinical Trial).
Status: UNKNOWN
Conditions: Clinical Performance
Interventions: PROCEDURE: endocrown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of the Movement Imitation Therapy in Preterm (MIT-PB) in Motor Behavior's Quality.
Status: RECRUITING
Conditions: Premature Birth|Risk
Interventions: OTHER: MIT-PB, movement imitation therapy for preterm.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation in Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Affective Disorder
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image-Guided Gynecologic Brachytherapy
Status: COMPLETED
Conditions: Cervical Cancer|Uterine Cancer|Vaginal Cancer|Carcinoma of the Vulva
Interventions: PROCEDURE: Image-guided brachytherapy|DRUG: 3'-Deoxy-3'-18f-Fluorothymidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Treatment of Intraventricular Hemorrhage
Status: COMPLETED
Conditions: Intraventricular Hemorrhage
Interventions: DRUG: tissue plasminogen activator, rt-PA (thrombolytic) (Cathflo)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mifepristone 2.5, 5, 10 mg Versus Placebo in the Treatment of Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Mifepristone|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of SI-B001+SI-B003± Chemotherapy in Patients With Locally Advanced or Metastatic Head and Neck Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: SI-B001|DRUG: SI-B003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0809: Capecitabine, Gemcitabine, and RT in Patients w/Cholangiocarcinoma of the Gallbladder or Bile Duct
Status: COMPLETED
Conditions: Extrahepatic Bile Duct Cancer|Gallbladder Cancer
Interventions: DRUG: capecitabine|DRUG: gemcitabine hydrochloride|RADIATION: 3-dimensional conformal radiation therapy|RADIATION: intensity-modulated radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Myelofibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis|Leukemia, Myelocytic, Acute|Myelodysplastic/Myeloproliferative Neoplasm|Myelodysplastic Syndrome (MDS)|Preleukemia|Primary Myelofibrosis|Myeloproliferative Disorders|Bone Marrow Disease|Hematological Disease|Precancerous Conditions|Neoplasms|Leukemia|Neoplasms by Histologic Type|Essential Thrombocytosis
Interventions: DRUG: Pelabresib (CPI-0610)|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration
Status: RECRUITING
Conditions: Age-Related Macular Degeneration
Interventions: BIOLOGICAL: VOY-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TRYHARD: Radiation Therapy Plus Cisplatin With or Without Lapatinib in Treating Patients With Head and Neck Cancer.
Status: COMPLETED
Conditions: Non-HPV Locally Advanced Head and Neck Cancer
Interventions: RADIATION: IMRT|DRUG: Cisplatin|DRUG: placebo|DRUG: Lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α
Status: COMPLETED
Conditions: Hypoxia|Normoxia|Hyperoxia
Interventions: DRUG: Lipopolysaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
Status: UNKNOWN
Conditions: Concentrated Growth Factors|Periodontal Regeneration|Furcation Defects
Interventions: PROCEDURE: GTR + CGF + bone graft|PROCEDURE: CGF + bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tigulixostat, Phase 3 Study, Placebo Controlled in Gout Patients
Status: RECRUITING
Conditions: Gout|Hyperuricemia|Gout Flare|Tophi
Interventions: DRUG: Tigulixostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of YPEG-rhG-CSF in Cancer Patients Receiving Chemotherapy
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|Breast Cancer
Interventions: DRUG: YPEG-rhG-CSF, 20μg/kg, single s.c. at 48hrs after chemotherapy for each experimental cycle|DRUG: YPEG-rhG-CSF, 30μg/kg, single s.c. at 48hrs after chemotherapy for each experimental cycle|DRUG: YPEG-rhG-CSF, 45μg/kg, single s.c. at 48hrs after chemotherapy for each experimental cycle|DRUG: PEG-rhG-CSF, 100μg/kg, single s.c. at 48hrs after chemotherapy for each experimental cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Glucocorticoid Low-dose Outcome in RheumatoId Arthritis Study
Status: COMPLETED
Conditions: RheumatoId Arthritis
Interventions: DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Compare the Safety and Efficacy of Botulax® Versus Botox® in Patients With Cervical Dystonia
Status: COMPLETED
Conditions: Cervical Dystonia
Interventions: DRUG: Botulinum toxin type A injection|DRUG: Botulinum Toxin Type A Injection [Botox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: hu14.18-Interleukin-2 Fusion Protein in Treating Young Patients With Recurrent or Refractory Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: hu14.18-Interleukin-2 fusion protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing WX-0593 to Crizotinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: WX-0593 Tablets|DRUG: crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Safety Evaluation of Patients Treated With the NEVO™ Sirolimus-eluting Coronary Stent. (NEVO II)
Status: TERMINATED
Conditions: Atherosclerotic Coronary Artery Disease
Interventions: DEVICE: NEVO™ Sirolimus-eluting Coronary Stent System|DEVICE: XIENCE V®/XIENCE PRIME™/PROMUS® Everolimus-eluting Coronary Stent System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of LMV-12 Combined With Osimertinib in NSCLC
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|RET Gene Mutation|MET Amplification|EGF-R Positive Non-Small Cell Lung Cancer
Interventions: DRUG: LMV-12(HE003)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety, and Tolerability of S6G5T-1 and S6G5T-3 for the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: S6G5T-3|DRUG: S6G5T-1|DRUG: S6G5T-5|DRUG: S6G5T-6|DRUG: S6G5T-7|DRUG: S6G5T-8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Noninvasive Hemoglobin Sensor (Rainbow Reusable DCI)
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Hemoglobin Sensor ((Rainbow Reusable DCI, DCIP))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Hyperosmolar Dextrose in Rotator Cuff Disorder With Bursitis
Status: COMPLETED
Conditions: Subacromial Bursitis
Interventions: PROCEDURE: 15% Dextrose|PROCEDURE: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensory Evaluation of Dexlansoprazole Delayed-Release Orally Disintegrating Tablets
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Erosive Esophagitis|Heartburn
Interventions: DRUG: Dexlansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Effectiveness and Safety of Varying Dose Strengths (100, 200, 300 and 400 mg) of Extended-release Tramadol HCl With Placebo for the Treatment of Osteoarthritis(OA) of the Knee and/or Hip
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DRUG: Tramadol HCl ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Temperature Rise Caused by Short or Long-wavelengths
Status: NOT_YET_RECRUITING
Conditions: Post-operative Pain
Interventions: DEVICE: Red Light|DEVICE: Blue Light
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: AMT-101 (oral)|OTHER: Placebo (oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Demonstration of an Anti-allergic Effect in Subjects Treated With Callergin Nasal Spray in Comparison to Untreated Subjects and Subjects Treated With Vis Alpin® Alpensalz Nasal Spray, All Suffering From Grass Pollen Induced Rhinitis/Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: DEVICE: nasal spray|OTHER: no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomechanical and Ultrasonic Assessment of the Achilles Tendon in Vivo (MEDUSAA)
Status: COMPLETED
Conditions: Alterations of the Achilles Tendon
Interventions: DEVICE: Ultrasound exam|BEHAVIORAL: IPAQ questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Treatment for Depression Via a Gamified Mobile Phone Application Based on a New Cognitive Model
Status: COMPLETED
Conditions: Depression|Depressive Disorder|Clinical Depression|Major Depressive Disorder
Interventions: OTHER: FTP-based therapeutic mobile-app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physiological Study of Human Cholesterol Metabolism and Excretion
Status: COMPLETED
Conditions: Coronary Heart Disease|Cardiovascular Disease|Dyslipidemia|Disorder of Cholesterol Metabolism
Interventions: DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Molecular Monitoring With Circulating Tumor DNA and Nivolumab Maintenance
Status: ACTIVE_NOT_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Nivolumab, IV, 240 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability, Pharmacokinetics and Food Effects of SHEN211 Tablet in Healthy Subjects
Status: RECRUITING
Conditions: Phase 1
Interventions: DRUG: SHEN211 tablets|DRUG: SHEN211 placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy Before & After Surgery in Patients With Resectable Gallbladder Cancer
Status: WITHDRAWN
Conditions: Stage I Gallbladder Cancer AJCC v8|Stage II Gallbladder Cancer AJCC v8|Stage IIA Gallbladder Cancer AJCC v8|Stage IIB Gallbladder Cancer AJCC v8|Stage III Gallbladder Cancer AJCC v8|Stage IIIA Gallbladder Cancer AJCC v8|Stage IIIB Gallbladder Cancer AJCC v8
Interventions: DRUG: Capecitabine|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of SR1375 in Adult Patients With CAP
Status: NOT_YET_RECRUITING
Conditions: Community-acquired Pneumonia
Interventions: DRUG: SR1375 capsule 3mg+regular treatments|DRUG: SR1375 capsule 1mg+regular treatments|DRUG: SR1375 capsule 0.3mg+regular treatments|DRUG: Placebo capsule+regular treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety, Tolerability, and Pharmacokinetics of Oral Doses for AC430 in Healthy Subjects
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: AC430
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Multicenter, Randomized, Placebo Controlled, Double Blinded Clinical Study of KD018 as a Modulator of Irinotecan Chemotherapy in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: DRUG: KD018|DRUG: Irinotecan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Improved Baduanjin Combined Cross-theoretical Model Based on Internet in Family Empowering Elderly PCI Cardiac Rehabilitation
Status: NOT_YET_RECRUITING
Conditions: Coronary Heart Disease
Interventions: OTHER: Traditional Chinese Medicine exercises - Baduanjin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safe and Well Visits by the Fire and Rescue Service to Prevent Falls and Improve Quality of Life in Older People
Status: TERMINATED
Conditions: Accidental Fall|Quality of Life|Aged
Interventions: OTHER: Fire and Rescue Service Safe and Well Visit|OTHER: Self-Determination Theory informed trial invitation letter|OTHER: Pen included with reminder questionaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Brinzolamide/Timolol Maleate Fixed Combination (AZARGA)|DRUG: Dorzolamide/timolol Maleate Fixed Combination (COSOPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nalmefene on the Quality of Resuscitation in Patients Under General Anesthesia
Status: RECRUITING
Conditions: Resuscitation
Interventions: DRUG: Nalmefene|DRUG: normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis
Status: RECRUITING
Conditions: Thrombocytopenia|Immune Thrombocytopenia|Myelodysplasia
Interventions: BIOLOGICAL: Blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC