pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Lamotrigine Treatment of Affective Instability in Borderline Personality Disorder
Status: COMPLETED
Conditions: Borderline Personality Disorder
Interventions: DRUG: Lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Ursodeoxycholic Acid Use in the Prevention of Gallstone Formation After Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Cholelithiasis
Interventions: DRUG: Ursodeoxycholic Acid|DRUG: Placebo|RADIATION: Gallbladder Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pramlintide Combined With Model Predictive Control Algorithm
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Closed loop with pramlintide|DEVICE: Closed loop without pramlintide|DRUG: Open loop with pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalation Study of Birinapant and Pembrolizumab in Solid Tumors
Status: TERMINATED
Conditions: Solid Tumors
Interventions: DRUG: Birinapant|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an EHR Interface to Reduce Dosage of Hydroxychloroquine
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatic Diseases
Interventions: OTHER: New e-prescribing interface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized Double Dummy Double Blind Dose Determining Place-bo Controlled Study to Evaluate Efficacy of Investigational Product E-RH-06 at 2 Dose Levels for the Metabolic Management of Chronic or Recurrent, Non-infective Nasal Congestion With-or-without Rhinorrhea.
Status: UNKNOWN
Conditions: Chronic Rhinitis
Interventions: DIETARY_SUPPLEMENT: E-RH-06|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fermented and Fiber-rich Food (FeFiFo) Study
Status: COMPLETED
Conditions: Metabolic Syndrome|Microbiome|Immune Function|Inflammation
Interventions: BEHAVIORAL: Dietary Fiber|BEHAVIORAL: Fermented Foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Angiography Combination Laparoscopy in Patients With Obscure Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Surgical Wound
Interventions: OTHER: rebleeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevalence of Incontinence and Risk Factors in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Questionnaire and micturition and drinking diaries|PROCEDURE: Uroflowmetry, pelvic floor EMG and bladderscan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role of Extracorporeal Shock Wave Therapy in the Treatment of Trapezial-Metacarpal Osteoarthritis. A Double Blind Randomized Controlled Study.
Status: COMPLETED
Conditions: Osteoarthritis Trapezial-metacarpal Joint
Interventions: DEVICE: Extracorporeal shock wave therapy STORZ MEDICAL Modulith SLK|DEVICE: Device: Sham extracorporeal shock wave therapy STORZ MEDICAL Modulith SLK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Primary With Secondary Repair of Based on Electrodiagnostic Assessment and Clinical Examination
Status: COMPLETED
Conditions: Peripheral Nerve Injury
Interventions: PROCEDURE: primary repair|PROCEDURE: secondary repair
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Biceps Strength and Electromyographic Activity After Proximal Biceps Tenotomy Versus Tenodesis in Patients With Arthroscopic Rotator Cuff Tear Repair
Status: COMPLETED
Conditions: Biceps Tendon Lesion
Interventions: DIAGNOSTIC_TEST: Measurement of Muscle strength using a dynamometer|DIAGNOSTIC_TEST: Range of motion clinical measurement (shoulder and elbow)|DIAGNOSTIC_TEST: Electromyography (EMG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Activating the Cholinergic Anti-Inflammatory Pathway in Healthy Volunteers and People With Inflammatory Arthritis
Status: RECRUITING
Conditions: Psoriatic Arthritis|Rheumatoid Arthritis|Ankylosing Spondylitis
Interventions: DEVICE: Ultrasound Stimulation|DEVICE: Non-active ultrasound stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: I-COPE Study: Opioid Use and Pain Management in Older Adults
Status: COMPLETED
Conditions: Chronic Pain|Opioids|Opioid-use Disorder
Interventions: BEHAVIORAL: I-COPE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Prospective Randomised Study of Efficacy, Safety and Costs of Talc Pleurodesis Under Medical Thoracoscopy and Pleurodesis Under Video-assisted Thoracoscopy Surgery for Recurrent Primary Spontaneous Pneumothorax
Status: COMPLETED
Conditions: Pneumothorax
Interventions: OTHER: talc pleurodesis under medical thoracoscopy|OTHER: pleurodesis under video-assisted thoracoscopy surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Virtual Walking for Neuropathic Pain in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury|Neuropathic Pain
Interventions: BEHAVIORAL: Virtual walking|BEHAVIORAL: Wheeling tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease.
Status: COMPLETED
Conditions: Chagas Disease|Trypanosoma Cruzi Infection
Interventions: DRUG: Benznidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Trial Comparing the New Endovenous Procedures Versus Conventional Surgery for Varicose Veins Due to Great Saphenous Vein Incompetence
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: High Ligation of the GSV|PROCEDURE: Endovenous Laser Ablation|PROCEDURE: Radiofrequency ablation|PROCEDURE: Foam Sclerotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metronomic Cyclophosphamide in Combination With Standard Chemotherapy for Squamous Cell Lung Carcinoma
Status: UNKNOWN
Conditions: Lung Cancer|Squamous Cell Carcinoma of the Lung|Locally Advanced and Metastatic Squamous Cell Carcinoma of the Lung
Interventions: DRUG: Intravenous Cisplatin & etoposide|DRUG: Intravenous Cisplatin & etoposide along with oral cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telerehabilitation-based Exercise Training in Constipated Patients
Status: ENROLLING_BY_INVITATION
Conditions: Constipation
Interventions: OTHER: Education with the telerehabilitation method. In addition, a "Constipation Training Booklet" will be sent via e-mail or WhatsApp|OTHER: Training and exercise practices with the telerehabilitation method.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of an Investigational Drug ALO-02 (Oxycodone Hydrochloride and Naltrexone Hydrochloride) in Patients With Moderate to Severe Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Pain|Low Back Pain|Analgesia
Interventions: DRUG: ALO-02|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolomic and BH3 Profiling of Esophageal Cancers: Identification of Novel Assessment Methods of Treatment Response for Precision Therapy
Status: TERMINATED
Conditions: Esophageal Cancer|Esophageal Adenocarcinoma|Esophageal Squamous Cell Cancer|Esophageal Neoplasms|Squamous Cell Carcinoma
Interventions: OTHER: Chemoradiotherapy|PROCEDURE: Esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of ABI-007 Plus S-1 as Second-line Chemotherapy in Advanced Gastric Cancer Patients
Status: COMPLETED
Conditions: Gastric Adenocarcinoma
Interventions: DRUG: Nanoparticle Albumin-Bound Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: Large loop electrosurgical excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Blood Brain Barrier Dysfunction and Postoperative Neurocognitive Disorders
Status: RECRUITING
Conditions: Neurocognitive Disorders|Postoperative Cognitive Dysfunction
Interventions: DIAGNOSTIC_TEST: Brain Imaging|DIAGNOSTIC_TEST: Cognitive Testing|DIAGNOSTIC_TEST: Blood Biomarkers
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Early Life Intervention in Pediatrics Supported by E-health - SMOKE
Status: RECRUITING
Conditions: Smoking Reduction|Asthma in Children|Wheezing|Non-Communicable Disease|Life Style|Behavior, Smoking
Interventions: BEHAVIORAL: Life-Style app|OTHER: Sham Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ginkgo Biloba for the Treatment of Vitiligo Vulgaris in Adolescents
Status: COMPLETED
Conditions: Vitiligo Vulgaris
Interventions: DIETARY_SUPPLEMENT: Ginkgo biloba
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of HRM and Specific Biomarkers of Inflammation in the Diagnosis of Patients With Dysphagia and Suspected EoE
Status: UNKNOWN
Conditions: Eosinophilic Esophagitis
Interventions: DIAGNOSTIC_TEST: High-resolution manometry|DIAGNOSTIC_TEST: Serum biomarkers|DIAGNOSTIC_TEST: Gastrointestinal Quality of Life index|DRUG: Omeprazole 20 MG Oral Tablet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients (STARLINGS Study)
Status: ENROLLING_BY_INVITATION
Conditions: Breast Fibrosis|Breast Cancer|Breast Cancer Female|Breast Neoplasms|Breast Carcinoma in Situ|Breast Carcinoma
Interventions: OTHER: no intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Epley Maneuver and COW Thorne Cooksey Exercise With Half Somersault Maneuver in BPPV
Status: COMPLETED
Conditions: BPPV
Interventions: OTHER: Group A|OTHER: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Combination Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin (RBV) in Genotype 2 Hepatitis C Infection (MK-5172-047)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Grazoprevir|DRUG: Elbasvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Remicade (Infliximab) in Moderate-to-Severe Chronic Plaque Psoriasis in the Middle Eastern Population (Study P04528)
Status: COMPLETED
Conditions: Psoriasis
Interventions: BIOLOGICAL: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Back on Track to Healthy Living Study
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Cognitive Therapy (CT)|BEHAVIORAL: Mindfulness Meditation (MM)|BEHAVIORAL: Activation Skills (AS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study
Status: COMPLETED
Conditions: Non-Alcoholic Fatty Liver Disease
Interventions: DRUG: Fish Oil Supplementation|DRUG: Placebo Supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Ounce-equivalents" in the Protein Foods Group: Benefits of Quality
Status: COMPLETED
Conditions: Protein Metabolism
Interventions: DIETARY_SUPPLEMENT: Pork intake|DIETARY_SUPPLEMENT: Mixed nuts intake|DIETARY_SUPPLEMENT: Tofu intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Pazopanib, Paclitaxel, and Carboplatin in Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor - Protocol Specific|Breast Cancer - Female
Interventions: DRUG: Pazopanib|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.
Status: ENROLLING_BY_INVITATION
Conditions: Blood and Lymphatic Diseases
Interventions: DRUG: BIVV003|DRUG: ST-400
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of Migraine
Status: COMPLETED
Conditions: Acute Migraine
Interventions: DRUG: Rimegepant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Weight Stigma by Association in Parent-Child Dyads
Status: COMPLETED
Conditions: Childhood Obesity|Obesity
Interventions: OTHER: Mother with obesity, daughter with obesity|OTHER: Mother with obesity, daughter without obesity|OTHER: Mother without obesity, daughter with obesity|OTHER: Mother without obesity, daughter without obesity|OTHER: Mother with obesity, son with obesity|OTHER: Mother with obesity, son without obesity|OTHER: Mother without obesity, son with obesity|OTHER: Mother without obesity, son without obesity|OTHER: Father with obesity, daughter with obesity|OTHER: Father with obesity, daughter without obesity|OTHER: Father without obesity, daughter with obesity|OTHER: Father without obesity, daughter without obesity|OTHER: Father with obesity, son with obesity|OTHER: Father with obesity, son without obesity|OTHER: Father without obesity, son with obesity|OTHER: Father without obesity, son without obesity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diabetes Nutrition Education and Healthy Food Resource for AIANs With T2D
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 2 Diabetes
Interventions: OTHER: Diabetes Nutrition Education Classes|OTHER: Healthy Food Security Resource
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral Artery Disease
Status: RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet|DRUG: Placebo|DRUG: Aspirin 81Mg Ec Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intracorporeal vs Extracorporeal Urinary Diversion After Robot Assisted Radical Cystectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: PROCEDURE: Extracorporeal Urinary Diversion|PROCEDURE: Intracorporal Urinary Diversion|DEVICE: Da Vinci Robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions
Status: RECRUITING
Conditions: Skin Lesion|Mucosal Lesion
Interventions: DIAGNOSTIC_TEST: Dermoscopic imaging|DIAGNOSTIC_TEST: 3-dimensional total body photography|DIAGNOSTIC_TEST: Confocal microscopy|DIAGNOSTIC_TEST: Optical Coherence Tomography imaging|DIAGNOSTIC_TEST: Ultrasound|DIAGNOSTIC_TEST: Hyperspectral imaging|DIAGNOSTIC_TEST: Electrical impedance spectroscopy|DIAGNOSTIC_TEST: Patient self-imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression
Status: RECRUITING
Conditions: Treatment Resistant Depression|Undergoing Deep Brain Stimulation (DBS) Surgery
Interventions: DEVICE: Abbott Laboratories Infinity™ implantable deep brain stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: The Effects of Platelet-Rich Plasma Versus Prolotherapy On Rotator Cuff Tendinopathy: A Randomized Controlled Trial.
Status: COMPLETED
Conditions: Rotator Cuff Tendinosis|Supraspinatus Strain|PRP
Interventions: BIOLOGICAL: Platelet-Rich Plasma|BIOLOGICAL: Prolotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Three Different Treatment Methods in Myofascial Pain Patients
Status: COMPLETED
Conditions: Temporomandibular Disorder
Interventions: DRUG: NSAID|DEVICE: oral appliance|OTHER: dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Double Regional Anesthesia in Video Assisted Thoracoscopy
Status: COMPLETED
Conditions: Video Assisted Thoracoscopy|Anesthesia
Interventions: DRUG: Serratus plane block and paravertebral block|DRUG: paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Accuracy of Continuous Glucose Sensors in People With Diabetes Undergoing Haemodialysis
Status: COMPLETED
Conditions: Diabetic Nephropathies|Type 1 Diabetes Mellitus|Chronic Kidney Diseases
Interventions: DEVICE: Dexcom G6 and Abbott Freestyle Libre
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mindfulness Intervention for People With Psychosis
Status: COMPLETED
Conditions: Recent-onset Psychosis
Interventions: BEHAVIORAL: Mindfulness-based cognitive therapy (psychosis)|BEHAVIORAL: Psychoeducation (psychosis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Antibiotics After Obstetric Perineal Tear
Status: RECRUITING
Conditions: Obstetric Trauma|Infections|Wound Dehiscence
Interventions: DRUG: Placebo|DRUG: Bioclavid (Amoxicillin and Clavulanic acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of DHA on Attention Deficit and Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DIETARY_SUPPLEMENT: docosahexaenoic acid|DIETARY_SUPPLEMENT: Wheat germ oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exposure and Response Prevention With Behavioral- Versus Cognitive Therapy Rationale in Obsessive Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: ERP cognitive therapy|BEHAVIORAL: ERP behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Staphylococcus Aureus Bacteremia: Impact of an Intervention Program in Improving the Clinical Management and Review of the Clinical and Molecular Epidemiology
Status: COMPLETED
Conditions: Staphylococcus Aureus Bacteremia
Interventions: BEHAVIORAL: Follow recommendations based on scientific evidence to S. aureus bacteremia management|BEHAVIORAL: Not to follow recommendations based on scientific evidence to S. aureus bacteremia management
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Lucinactant on Mucus Clearance in Cystic Fibrosis Lung Disease
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Lucinactant first|DRUG: Placebo first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: acalabrutinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS-EEG as a Tool to Study the Neuromodulatory Effects of Theta Burst Stimulation
Status: COMPLETED
Conditions: Cortical Excitability
Interventions: DEVICE: theta burst stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Open, Randomized, Two Way Crossover Study Comparing the Effect of Esomeprazole Adminstered Orally and iv
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of iR2 in Untreated and Unfit Elderly Patients With DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of AVID200, a Transforming Growth Factor β (TGFβ) Inhibitor, in Patients Malignancies
Status: UNKNOWN
Conditions: Malignant Solid Tumor
Interventions: DRUG: AVID200
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SBRT Combined With AK104 to Treatment Relapsed or Metastatic ESCC
Status: NOT_YET_RECRUITING
Conditions: Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: SBRT|DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19
Status: COMPLETED
Conditions: Covid19|Corona Virus Infection
Interventions: DIAGNOSTIC_TEST: Biochemistry blood test|DIAGNOSTIC_TEST: Hematology blood test|DIAGNOSTIC_TEST: D-Dimer test (coagulation)|DIAGNOSTIC_TEST: Inflammatory markers|DIAGNOSTIC_TEST: Vital signs|DIAGNOSTIC_TEST: VAS scale|DIAGNOSTIC_TEST: WHO Ordinal Score|DIAGNOSTIC_TEST: COVID-19-Related Symptoms assessment|DIAGNOSTIC_TEST: COVID-19-Impact on Quality-of-Life Questionnaire|DIAGNOSTIC_TEST: POST- COVID-19 Functional Status Scale:|DIAGNOSTIC_TEST: Pregnancy test|DIAGNOSTIC_TEST: Physical examination|DIAGNOSTIC_TEST: PK parameters|DIAGNOSTIC_TEST: SARS-CoV-2 test (PCR)|DIAGNOSTIC_TEST: ECG|DRUG: Treatment administration (twice a day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Noninferiority Oral Tranexamic Acid vs Intravenous Administration in Total Hip Arthroplasty
Status: COMPLETED
Conditions: Hemorrhage Postoperative|Total Blood Loss|Arthroplasty Complications
Interventions: DRUG: Tranexamic Acid Oral Product|DRUG: Tranexamic acid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: Talazoparib + Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Backward Gait Training With Exoskeleton on Motor Functions
Status: RECRUITING
Conditions: Gait, Hemiplegic|Physical Therapy
Interventions: DEVICE: Gait training with EksoNR|PROCEDURE: Backward gait training with EksoNR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pexiganan Versus Placebo Control for the Treatment of Mild Infections of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Infection
Interventions: DRUG: Topical pexiganan cream 0.8%|DRUG: Topical placebo cream|OTHER: Standard wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: DRUG: D-Amphetamine 30mg|DRUG: D-Amphetamine 60mg|DRUG: Modafinil 200mg|DRUG: Modafinil 400mg|BEHAVIORAL: Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Gabapentin in Treating Pain in Children With SNI (Gabapentin Trial)
Status: RECRUITING
Conditions: Pain|Neuropathic Pain|Irritability
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Bevacizumab With Chemotherapy Followed by Pembrolizumab, Bevacizumab and Olaparib in Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Carcinoma, Ovarian Epithelial
Interventions: BIOLOGICAL: pembrolizumab|DRUG: olaparib|BIOLOGICAL: bevacizumab|DRUG: carboplatin|DRUG: paclitaxel|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etrasimod for Immune Checkpoint Inhibitor Diarrhea and Colitis
Status: NOT_YET_RECRUITING
Conditions: Immune Checkpoint Inhibitor-Related Diarrhea and Colitis
Interventions: DRUG: Etrasimod|DRUG: Placebo|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Different Treatment Methods on the Apical Closure and Treatment Success in Permanent First Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Symptomatic Reversible Pulpitis (Disorder)
Interventions: PROCEDURE: Direct Pulp Capping with ProRoot MTA|PROCEDURE: Pulpotomy with ProRoot MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid
Status: COMPLETED
Conditions: Cocaine Dependence, in Remission|Cocaine Abuse, in Remission|Cocaine-Related Disorders
Interventions: DRUG: Clavulanic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Female With Non-cyclic Chronic Pelvic Pain
Status: UNKNOWN
Conditions: Chronic Pelvic Pain
Interventions: DEVICE: Acupuncture|DEVICE: Sham acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Status: UNKNOWN
Conditions: Cataract
Interventions: PROCEDURE: Cataract surgery with Artis Active IOLs|PROCEDURE: Cataract surgery with AT Lara IOLs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New Imaging Biomarkers Predictive of MA Progression
Status: RECRUITING
Conditions: Alzheimer Disease|Magnetic Resonance Spectroscopy|Ultra High Field 7T|Progression of Disease|MR Biomarkers
Interventions: OTHER: MRI follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Skin Antisepsis After Skin Closure on Wound Infection After Abdominal Surgery for Sepsis: a Preliminary Report
Status: COMPLETED
Conditions: Antisepsis
Interventions: OTHER: 10% povidone iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Wearing the 'Nike Free'Shoe on Isokinetic Muscle Strength of Foot and Ankle and on Proprioception.
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Wearing the "Nike Free" shoe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: BL Infusion Trial:Beta-lactam Continuous Versus Intermittent Infusion and Associated Bacterial Resistance and Therapy Outcomes in Critically Ill Patients With Severe Pneumonia
Status: TERMINATED
Conditions: Pneumonia
Interventions: DRUG: Cefepime, Meropenem, or Piperacillin/Tazobactam|DRUG: Cefepime, Meropenem, or Piperacillin/Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: VNRX-5133 and VNRX-5022
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Contingency Management for PrEP Adherence and/or Methamphetamine Use
Status: COMPLETED
Conditions: Methamphetamine-dependence|HIV-1-infection
Interventions: BEHAVIORAL: Contingency Management-ART|BEHAVIORAL: Contingency Management-Methamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Enhanced SUPport for Initiation and paRticipation in a FOOD is Medicine Program
Status: RECRUITING
Conditions: Cardiac Rehabilitation|Nutrition, Healthy|Nutrition Poor
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Navigation|BEHAVIORAL: Text Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Role of Ivermectin Nanosuspension as Nasal Spray in Treatment of Persistant Post covid19 Anosmia
Status: UNKNOWN
Conditions: Anosmia
Interventions: DRUG: intranasal spray ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superior Capsular Reconstruction vs. Partial Repair for Massive Rotator Cuff Tears
Status: RECRUITING
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Superior Capsular Reconstruction|PROCEDURE: Partial Repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Radiofrequency Ablation on Left Ventricular Function in Supraventricular Tachyarrhythmias Patient Using Speckle Tracking Echocardiography
Status: NOT_YET_RECRUITING
Conditions: Left Ventricular Function, Arrhythmia
Interventions: DIAGNOSTIC_TEST: radiofrequency ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous Iron Treatment in Patients With Heart Failure and Iron Deficiency: IRONMAN
Status: COMPLETED
Conditions: Chronic Heart Failure|Iron Deficiency|Left Ventricular Systolic Dysfunction
Interventions: DRUG: Ferric Derisomaltose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Cincalcet on Cognitive Functions in Healthy Human Subjects
Status: COMPLETED
Conditions: Memory Functions
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of P-Gemox vs.EPOCH as First-line Chemotherapy to Treat NK/T-cell Lymphoma With Early Stage
Status: TERMINATED
Conditions: Lymphoma, Extranodal NK-T-Cell
Interventions: DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Pegaspargase|DRUG: Etoposide|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Prednisone|RADIATION: IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Psychocognitive Impairments in Adolescents Surviving Childhood Leukemia : LEA-PsyCog
Status: UNKNOWN
Conditions: Adolescents Surviving Childhood Leukemia LEA
Interventions: OTHER: neuropsychological evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: Pfs230D1M-EPA/Alhydrogel|BIOLOGICAL: Pfs25M-EPA/Alhydrogel|DRUG: TWINRIX|DRUG: Menactra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gene Expression Changes In Young and Geriatric Skin
Status: RECRUITING
Conditions: UVB Phototherapy Burn|Insulin-like Growth Factor 1|Aging
Interventions: DRUG: Insulin-Like Growth Factor 1|OTHER: No Insulin-Lie Growth Factor 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multiple Antigen Specific Cell Therapy (MASCT) for Hepatocellular Carcinoma(HCC) Patients After Radical Resection or Radio Frequency Ablation(RFA).
Status: SUSPENDED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: MASCT:Multiple Antigens Specific Cellular Therapy|OTHER: The foundation treatment including against hepatitis b virus treatment using nucleoside analogue drug and protect liver treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Peginterferon and Ribavirin to Treat Chronic Hepatitis C in Patients Infected With HCV Genotype 2 or 3
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Peginterferon alfa-2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effects of Absorbable and Non-absorbable Suture in Bronchial Sleeve Resection
Status: RECRUITING
Conditions: Suture, Complication
Interventions: DEVICE: Absorbable Suture|DEVICE: Non-absorbable Suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Alternative Vaccination Schedule of Oral Cholera Vaccine
Status: COMPLETED
Conditions: Cholera|Diarrhoea|Vibrio Infection
Interventions: BIOLOGICAL: Modified killed oral cholera vaccine at 14 day interval|BIOLOGICAL: Modified killed oral cholera vaccine at 28 day interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Distal Urethral Cancer|Proximal Urethral Cancer|Squamous Cell Carcinoma of the Bladder|Stage II Bladder Cancer|Stage III Bladder Cancer|Urethral Cancer Associated With Invasive Bladder Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: cisplatin|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Atraumatic Technique in Ophthalmic Patients
Status: COMPLETED
Conditions: Intravenous Cannula Regional Ophthalmic Anesthesia
Interventions: DEVICE: Cannula plastic part while applying peribulbar block|PROCEDURE: traditional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: eHealth in Treatment of Gestational Diabetes (eMOMGDM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Gestational Diabetes|Mobile Application
Interventions: DEVICE: eMOM GDM application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bypass Angioplasty Revascularization Investigation (BARI)
Status: COMPLETED
Conditions: Angina Pectoris|Cardiovascular Diseases|Coronary Disease|Diabetes Mellitus|Heart Diseases|Myocardial Ischemia
Interventions: PROCEDURE: angioplasty, transluminal, percutaneous coronary|PROCEDURE: coronary artery bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Potential Benefits of Black Seed Oil Supplementation on Asthma Inflammation and Outcomes
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Black seed oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of SKI-G-801 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: SKI-G-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of EPA/DHA Supplementation on Cognitive Control in Children With ADHD
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder|Healthy
Interventions: DIETARY_SUPPLEMENT: Eicosapentaenoic acid / Docosahexaenoic acid|DIETARY_SUPPLEMENT: Placebo dietary intervention (MUFA) in ADHD group|DIETARY_SUPPLEMENT: Eicosapentaenoic acid / Docosahexaenoic acid|DIETARY_SUPPLEMENT: Placebo dietary intervention (MUFA) in healthy control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Olanzapine in the Treatment of Patients With Anorexia Nervosa
Status: COMPLETED
Conditions: Anorexia Nervosa
Interventions: DRUG: Olanzapine|BEHAVIORAL: Day Hospital
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome
Status: TERMINATED
Conditions: Short Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Enterade® oral rehydration solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM
Status: UNKNOWN
Conditions: Hypertrophic Obstructive Cardiomyopathy (HOCM)
Interventions: DEVICE: Biventricular pacing|DEVICE: No Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SPSIPB and CPB on Clavicle Surgeries
Status: COMPLETED
Conditions: Clavicle Fracture|Postoperative Pain|Analgesia
Interventions: PROCEDURE: Serratus posterior superior intercostal plane block and clavipectoral plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pegylated Interferon and Ribavirin Therapy in Chronic Hepatitis Genotype 4
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Pegylated IFN- alpha 2b|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke
Status: TERMINATED
Conditions: Cerebrovascular Accident|Sleep Disorder
Interventions: DEVICE: CES|DEVICE: CES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Tamoxifen Compared With Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: tamoxifen citrate|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comminuted Fractures of the Midshaft of the Tibia; (Interlocking Nail +/- Blocking Screws or Locked Plating With Predicted Distribution of Locking Screws) Choice Based on Finite Element Analysis Correlated With Clinical Outcome and Union.
Status: COMPLETED
Conditions: Comminuted Fracture Tibia
Interventions: OTHER: Finite element analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the High-resolution, Contrast Enhanced Low-dose Breast-CT
Status: UNKNOWN
Conditions: BI-RADS 4|BI-RADS 5|BI-RADS 6|High Risk of Breast Cancer Which Indicates a Mamma-MRI
Interventions: DEVICE: Native and dynamic contrast-enhanced CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Oxycodone vs. Fentanyl in Early Postoperative Pain After Total Hip Replacement
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Oxycodone|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Intervention to Promote Cardiovascular Health of Mothers and Children
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: ENRICH pilot intervention (full intervention)|BEHAVIORAL: ENRICH pilot intervention (partial intervention: only diet and physical activity)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy in Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: ADSTEM Inj.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PS-341 in Treating Patients With Advanced Cancer
Status: COMPLETED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Precancerous Condition|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT