pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Shoulder Abduction Brace Against Normal Sling After Arthroscopical Rotator Cuff Suture.
Status: COMPLETED
Conditions: Supraspinatus Injury
Interventions: PROCEDURE: Brace|PROCEDURE: Normal sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Progression-free Survival (PFS) and Evaluate Participant Experience for Participants With Metastatic Anaplastic Lymphoma Kinase-positive (ALK+) Non-Small Cell Lung Cancer (NSCLC) Treated With Anaplastic Lymphoma Kinase (ALK) Inhibitors
Status: COMPLETED
Conditions: Anaplastic Lymphoma Kinase-positive|Carcinoma Non-small-cell Lung
Interventions: DRUG: Brigatinib|DRUG: Alectinib|DRUG: Ceritinib|DRUG: Lorlatinib|DRUG: Any FDA Approved ALK Inhibitors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)
Status: RECRUITING
Conditions: Congenital Heart Disease in Children
Interventions: DEVICE: Ductal Arterial Stent|PROCEDURE: Systemic-to-Pulmonary Artery Shunt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerance and Pharmacokinetics Clinical Study of VC005 in Healthy Subjects and Patients With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: VC005|DRUG: VC005 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Placebo Controlled Study of Cannabidiol in Young Adult Cannabis Users
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Broad Spectrum Cannabidiol (bsCBD) 400 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Microdecompression Versus Open Laminectomy and Posterior Stabilization for Multilevel Lumbar Spine Stenosis
Status: COMPLETED
Conditions: Lumbar Spinal Stenosis
Interventions: PROCEDURE: Microdecompression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sore Throat After Intubation Using Glidescope With Stylet and Bougie
Status: COMPLETED
Conditions: Postoperative Sore Throat
Interventions: DEVICE: a device to facilitate endotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment With Leflunomide in Patients With Polymyalgia Rheumatica
Status: UNKNOWN
Conditions: Polymyalgia Rheumatica
Interventions: DRUG: Leflunomide 20 mg|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Plasmatic Catecholamines: Randomized Controlled Trial Comparing Epidural Versus Combined Spinal-epidural
Status: COMPLETED
Conditions: Fetal Bradycardia|Hypertonic Uterine|Catecholamines
Interventions: DRUG: Epidural bupivacaine with vasoconstrictor 0.125%|DRUG: Epidural sufentanil|PROCEDURE: Placement of the epidural catheter|DRUG: Intrathecal hyperbaric bupivacaine solution 0.5%|DRUG: Intrathecal morphine|PROCEDURE: Placement of an epidural catheter to the catheter through technical needle|DRUG: Intrathecal sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Controlled Trial on Surgical Treatment of Type 2 Diabetes Patients With BMI 25-30 by Means of Biliopancreatic Diversion
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Bariatric Surgery|Biliopancreatic Diversion
Interventions: PROCEDURE: biliopancreatic diversion|DRUG: antidiabetics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "VIBES"--Low Magnitude Mechanical Stimulation to Improve Bone Mineral Density
Status: COMPLETED
Conditions: Osteopenia
Interventions: DEVICE: Low magnitude mechanical stimulation|DEVICE: Sham low magnitude mechanical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Chronic Obstructive Pulmonary Disease (COPD) Trial Investigating Roflumilast on Safety and Effectiveness in China, Hong Kong and Singapore:
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Roflumilast|DRUG: Placebo|DRUG: Salbutamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Papilloma Virus Infection|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Stage IVB Squamous Cell Carcinoma of the Oropharynx
Interventions: PROCEDURE: Transoral surgery|RADIATION: intensity-modulated radiation therapy|DRUG: cisplatin|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing ONC201 to Prevent Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Colorectal Adenomatous Polyp|Colorectal Carcinoma|Familial Adenomatous Polyposis|Multiple Adenomatous Polyps
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Colonoscopy|DRUG: Dordaviprone|OTHER: Questionnaire Administration|PROCEDURE: Sigmoidoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PECS Block in Partial Mastectomy for Postoperative Pain Control
Status: UNKNOWN
Conditions: Breast Cancer|Postoperative Pain|Opioid Use|Local Anesthesia
Interventions: PROCEDURE: Pectoral Nerve Block|PROCEDURE: Surgery without Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and the Change of sAg Levels in Chronic Hepatitis B Patients Receiving Clevudine Treatment Over the Long Period
Status: TERMINATED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Clevudine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rigid Taping Versus Scapular Stabilizing Exercises in Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Impingement Syndrome of Ankle
Interventions: OTHER: rigid tapping|OTHER: scapular stabilizing excercise|OTHER: therapeutic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intracavitary Cisplatin-Fibrin Localized Chemotherapy After P/D or EPP for Malignant Pleural Mesothelioma
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma
Interventions: COMBINATION_PRODUCT: intracavitary cisplatin-fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of Cipro® XR in Treating Female Patients With Lower Urinary Tract Infections
Status: COMPLETED
Conditions: Urinary Tract Infection
Interventions: DRUG: Ciprofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) Repair
Status: COMPLETED
Conditions: Acute Kidney Injury|Abdominal Aortic Aneurysm
Interventions: DRUG: curcumin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Gefitinib in Treating Patients With Advanced Unresectable Hepatocellular Carcinoma (Liver Cancer)
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Recurrent Adult Primary Liver Cancer
Interventions: DRUG: gefitinib|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study for Safety and Efficacy of InSpace™ in Rotator Cuff Tear Subjects
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: DEVICE: SpaceGuard Balloon
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Sitagliptin for HIV Insulin Resistance and Inflammation
Status: COMPLETED
Conditions: Inflammation|Macrophage Infiltration|Cardiovascular Disease
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Ascorbic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sodium Bicarbonate on Exercise Performance
Status: COMPLETED
Conditions: Sodium Bicarbonate
Interventions: DIETARY_SUPPLEMENT: Sodium Bicarbonate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cross-sectorial Use of Patient-Reported Outcomes in Chronic Degenerative Shoulder Conditions
Status: NOT_YET_RECRUITING
Conditions: Shoulder Disease|Shoulder Impingement|Shoulder Osteoarthritis|Shoulder Frozen|Shoulder Capsulitis|Shoulder Bursitis|Shoulder Impingement Syndrome|Rotator Cuff Syndrome|Rotator Cuff Syndrome of Shoulder and Allied Disorders
Interventions: OTHER: Systematic use of patient reported outcome measures in clinical work with the patients
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial
Status: COMPLETED
Conditions: Children Born Extremely Premature|Disturbance of Visuo-spatial Working Memory
Interventions: OTHER: computerized cognitive remediation program|OTHER: standard remediation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: Ablation of Celiac Ganglion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomization to Endovascular Treatment Alone or Preceded by Systemic Thrombolysis With Tenecteplase in Ischemic Stroke
Status: RECRUITING
Conditions: Stroke, Ischemic|Stroke, Acute
Interventions: DRUG: Tenecteplase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Supplementation of Dual Probiotic Strains Reduced Fasting Triglyceride and Enhanced Apolipoprotein A-V Levels
Status: COMPLETED
Conditions: Hypertriglyceridemia
Interventions: DIETARY_SUPPLEMENT: dual probiotics|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Evaluate the Impact of Liquid Biopsy in Participants With a Clinical Diagnosis of Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Lung Cancer|Metastatic Gastrointestinal Cancer
Interventions: DIAGNOSTIC_TEST: FoundationOne® Liquid CDx Assay|DIAGNOSTIC_TEST: Standard of Care Diagnostic Pathway
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Radiofrequency Ablation Using Cooled-Wet Electrode
Status: COMPLETED
Conditions: HCC|Metastasis
Interventions: DEVICE: cooled-wet electrode|DEVICE: separable clustered electrode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Mycophenolate Mofetil (MMF) on Surrogate Markers for Cardiovascular Disease in HIV-1 Infected Patients
Status: UNKNOWN
Conditions: HIV Infection|Atherosclerosis
Interventions: DRUG: mycophenol mofetil (MMF, Cellcept®) 500 mg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Caudal epidural injection|PROCEDURE: Percutaneous adhesiolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Inferior Turbinate Reduction in Pediatric Population Failing Surgery for Sleep Disordered Breathing
Status: TERMINATED
Conditions: Sleep Related Breathing Disorder|Upper Airway Resistance Syndrome|Obstructive Sleep Apnea
Interventions: PROCEDURE: Cold ablation inferior turbinate reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hippocampal Stimulation in Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Pain|Back Pain|Pain
Interventions: DEVICE: Transcranial Magnetic Stimulation|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Range of Motion Exercises on Fatigue and Sleep Quality in Hemodialysis
Status: NOT_YET_RECRUITING
Conditions: Renal Failure
Interventions: BEHAVIORAL: rom exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study Comparing the Effectiveness of Two Different Methods of Acoustic Stimulation
Status: COMPLETED
Conditions: Sleep Deprivation|Insufficient Sleep Syndrome|Healthy
Interventions: DEVICE: PowerSleep Stim|DEVICE: Northwestern Stim|DEVICE: PowerSleep Sham|DEVICE: NorthWestern Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of MEDI0382 on Hepatic Glycogen Metabolism in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: MEDI0382|DRUG: Placebo|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Four-Part Study to Assess the Safety, Tolerability, PK and PD of ONO-5788 in Healthy Adult Volunteers
Status: TERMINATED
Conditions: Acromegaly
Interventions: DRUG: ONO-5788|DRUG: ONO-5788 Placebo|DRUG: Octreotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: CT001|DRUG: Placebo|DRUG: Sufentanil|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Status: COMPLETED
Conditions: Adult Primary Hepatocellular Carcinoma|Advanced Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer
Interventions: DRUG: cediranib maleate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Fermented Vegetables on Gut Microflora and Inflammation in Women
Status: COMPLETED
Conditions: Inflammation|Women's Health|Gastrointestinal Microbiome
Interventions: OTHER: Fermented vegetable|OTHER: Non-fermented vegetable
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma
Status: COMPLETED
Conditions: Ganglioneuroblastoma|Recurrent Neuroblastoma
Interventions: BIOLOGICAL: Dinutuximab|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Sargramostim|DRUG: Temozolomide|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Quadratus Lumborum Block to Reduce Opioid Need in Patients After Pancreatic Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Carcinoma
Interventions: OTHER: Best Practice|DRUG: Quadratus Lumborum Block|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Stone|Renal Stone|Urolithiasis
Interventions: DEVICE: SURE|DEVICE: Standard Ureteroscopy (Basketing)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corticosteroids for Acute Migraine in the Emergency Department
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: metoclopramide|DRUG: Dexamethasone|DRUG: methylprednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Use of Intorus to Control Anxiety Before Exams in Students at the University of Extremadura
Status: COMPLETED
Conditions: STUDENT|Anxiety Disorders
Interventions: DEVICE: INTORUS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Long Term Effect of Aggressive Nutritional Management on Survival in Patients With Alcoholic Liver Disease
Status: COMPLETED
Conditions: Alcoholic Liver Disease
Interventions: DIETARY_SUPPLEMENT: Polymeric nutritional supplements|DIETARY_SUPPLEMENT: Standard Nutrional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma
Interventions: COMBINATION_PRODUCT: LTX-315 in combination with pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Hypobaric Local Anesthetic Study
Status: RECRUITING
Conditions: Anesthesia, Local
Interventions: DRUG: Spinal hypobaric Mepivacaine Local Anesthetic Injection|DRUG: Spinal hypobaric Bupivacaine Local Anesthetic Injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial Investigating Efficacy of G-POEM
Status: RECRUITING
Conditions: Gastroparesis With Diabetes Mellitus
Interventions: PROCEDURE: G-POEM|PROCEDURE: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents
Status: RECRUITING
Conditions: Asthma|Asthma in Children|Dyspnea|Cough|Pneumonia|Wheezing|Shortness of Breath|Chest Tightness|Lower Respiratory Tract and Lung Infections|Recurrent Respiratory Tract Infections|Mucus; Plug
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Endoscopic Submucosal Dissection (ESD) and Endoscopic Mucosal Band Ligation (EMBL) for Early Cancer
Status: UNKNOWN
Conditions: Early Cancer
Interventions: PROCEDURE: endoscopic submucosal dissection (ESD) and endoscopic mucosal band ligation (EMBL) for early cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Fulvestrant With or Without Enzalutamide in ER+/Her2- Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Enzalutamide|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Adriamycin Plus Cyclophosphamide Followed by Abraxane as Adjuvant Therapy for Patients With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Abraxane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Recombinant Hyaluronidase Human is Effective for the Use of Local Blocks for Eyelid's Surgery
Status: WITHDRAWN
Conditions: Upper Eyelid Surgery
Interventions: DRUG: Hyaluronidase|OTHER: 2 mL of lidocaine 2% with epinephrine 1:100,000 without rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism
Interventions: DEVICE: Laguna Thrombectomy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Doxil and Multiday Vinorelbine in Patients With Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Doxil and Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Walking and Heating on Vascular Function in Diabetic Patients
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity
Interventions: BEHAVIORAL: Walking: Intervention arm in diabetics|OTHER: Walking: No intervention in diabetics|OTHER: Walking: Healthy cohort as reference controls|BEHAVIORAL: Lower body heating: Intervention arm in healthy subjects|BEHAVIORAL: Lower body heating: Intervention arm in diabetics|OTHER: Lower body heating: Healthy cohort as reference controls
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of MTA Versus Biodentine as Pulpotomy Agents in Immature First Permanent Molars
Status: COMPLETED
Conditions: Carious Exposure of Pulp
Interventions: BIOLOGICAL: Biodentine|BIOLOGICAL: MTA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychiatric Advance Directives for Improved Mental Health Care
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective|Bipolar Disorder|Stress Disorders, Post-traumatic|Psychotic Disorders
Interventions: PROCEDURE: Psychiatric Advance Directives intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Tolerability of Vilazodone in Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Dose-matched placebo|DRUG: Vilazodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Implementing Shared Decision-Making on Quality of Care Among Patients With Lumbar Degenerative Diseases.
Status: COMPLETED
Conditions: Lumbar Degenerative Disease|Shared Decision Making|Patient Decision Aids|Evidence-based Medicine|Quality of Care
Interventions: OTHER: Shared decision making support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis
Status: RECRUITING
Conditions: Frostbite
Interventions: DEVICE: Long-Acting silver dressings|OTHER: Aloe Vera|DRUG: Dalbavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of the Effectiveness of Aquatic Exercise on the Static and Dynamic Balance in Pregnant Women
Status: COMPLETED
Conditions: Pregnancy|Aquatic Physical Exercise|Balance
Interventions: OTHER: Aquatic exercise - own monitors program|OTHER: Aquatic exercise - AIPAP program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease
Status: COMPLETED
Conditions: Intermittent Claudication
Interventions: OTHER: Placebo|DRUG: Sapropterin Dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dermatology and Teledermatology Consultations on Length of Hospital Admission, 30 Day Readmission Rate, and Antibiotic Use in Patients Presenting With Cellulitis vs Pseudocellulitis in an Academic Inpatient Setting
Status: COMPLETED
Conditions: Cellulitis
Interventions: OTHER: teledermatology consult|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Post-Vitrectomy Lenstatin™ Study
Status: COMPLETED
Conditions: Cataract, Nuclear Progressive
Interventions: DIETARY_SUPPLEMENT: Lenstatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Time to Remission of Depressive Symptoms With Combined SSRI and Ramelteon
Status: TERMINATED
Conditions: Major Depressive Disorder|Insomnia
Interventions: DRUG: Escitalopram|DRUG: Ramelteon|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Serum Derived Bovine Immunoglobulin in Children With Diarrhea Predominant IBS
Status: COMPLETED
Conditions: Diarrhea Predominant Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Serum-Derived Bovine Immunoglobulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurostimulation for Respiratory Function After Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Cervical Spinal Cord Injury|Respiratory Function Impaired
Interventions: DEVICE: Neurostimulation|OTHER: Repiratory training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer Patients
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: Pazopanib (GW786034)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess Safety and Efficacy of Kabiven® in Pediatric Patients 2 to 16 Years of Age
Status: WITHDRAWN
Conditions: Malnutrition
Interventions: DRUG: Kabiven®|DRUG: Compounded standard parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Potentiation of Trauma Exposure in Post-traumatic Stress Disorder by Repeated Transcranial Magnetic Stimulation
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: rTMS 1Hz|DEVICE: rTMS 10Hz|BEHAVIORAL: psychoneurological assessment|DEVICE: conductivity meter|DEVICE: electrocardiogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Intensive Pharmacokinetics Sub-study of Encore1 (ENCORE1-PK)
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Efavirenz|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Effects of Robot-assisted Gait Training in Patients Burn Injury on Lower Extremity
Status: COMPLETED
Conditions: Burns|Gait Disorder, Sensorimotor
Interventions: DEVICE: Robot assisted gait training|OTHER: conventional gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-drug Interaction Study of Biktarvy and Bemnifosbuvir/Ruzasvir
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: Cohort 1: Days 1-7 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered. Days 8-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 BIK|DRUG: Cohort 2: Days 1-10 Biktarvy (BIK). Days 11-17 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered + Biktarvy (BIK). Days 18-24 Bemnifosbuvir (BEM)/Ruzasvir (RZR) co-administered.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of PUR 0110 Rectal Enema in Normal Healthy Volunteers
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: PUR 0110 Rectal Enema or Placebo Enema|DRUG: PUR 0110 Rectal Enema or Placebo Enema|DRUG: PUR 0110 Rectal Enema or Placebo Enema|DRUG: PUR 0110 Rectal Enema or Placebo Enema
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vericiguat on Endpoint Events in Acute Coronary Syndrome( ACS）Patients With Ejection Fraction <45%
Status: RECRUITING
Conditions: Acute Coronary Syndrome|Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Vericiguat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Camrelizumab in Combination With Chemotherapy Regimen Comparative Chemotherapy Regimen for Metastatic Triple-negative Breast Cancer
Status: TERMINATED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Camrelizumab、Capecitabine/eribulin/gemcitabine/vinorelbine|DRUG: Capecitabine/eribulin/gemcitabine/vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.
Status: RECRUITING
Conditions: Acne Vulgaris
Interventions: DRUG: Metformin and doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Podiatry on Plantar Pain
Status: COMPLETED
Conditions: Heel Pain|Plantar Fasciitis|Plantar Pain
Interventions: PROCEDURE: chiropody|PROCEDURE: basic orthesis|PROCEDURE: advantage orthesis|PROCEDURE: chiropody and advantage orthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Fixed Dose STI571 (Imatinib Mesylate) With Escalating Doses of Docetaxel in Patients With Metastatic Androgen-Independent Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: imatinib mesylate|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vasopressin, Epinephrine, and Steroids for Cardiac Arrest
Status: COMPLETED
Conditions: Cardiac Arrest
Interventions: DRUG: Vasopressin, Epinephrine, Methylprednisolone, Hydrocortisone|DRUG: Standard CPR Protocol with Epinephrine and two Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard PCNL Vs Endoscopic Combined Intrarenal Surgery (ECIRS) for Complex Nephrolithiasis in Obese Patients
Status: RECRUITING
Conditions: Renal Stone
Interventions: PROCEDURE: Endoscopic combined intrarenal surgery|PROCEDURE: Percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tolerability of MMF vs EC-MPS in Maintenance Transplant Patients Treated With Calcineurin Inhibitors
Status: UNKNOWN
Conditions: Organ Transplantation
Interventions: DRUG: MMF|DRUG: EC-MPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Mechanisms Underlying Human Social Behavior
Status: COMPLETED
Conditions: Decision Making|Executive Function|Dopamine
Interventions: DRUG: Tolcapone 200 MG|OTHER: Functional Magnetic Resonance Imaging (fMRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of an Intervention on University Students' Mental Health and Learning During COVID-19
Status: UNKNOWN
Conditions: Mental Health Issue|Learning Problem|Student Burnout|Motivation|Young Adults/ Students|University-based Intervention
Interventions: OTHER: University-based intervention to promote better management of emotions and learning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Computed Guided Prolotherapy Versus Conventional Prolotherapy
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Orofacial Pain
Interventions: PROCEDURE: Conventional arthrocentesis followed by I-PRF injection|PROCEDURE: 3d surgical guided Arthrocentesis followed by I-PRF injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer
Status: RECRUITING
Conditions: Oral Mucositis
Interventions: DRUG: RRx-001|RADIATION: Intensity Modulated Radiation Therapy (IMRT)|DRUG: Cisplatin for injection 100 mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxychloroquine in ANCA Vasculitis Evaluation
Status: ACTIVE_NOT_RECRUITING
Conditions: ANCA Associated Vasculitis|Microscopic Polyangiitis|Churg-Strauss Syndrome|Wegener Granulomatosis
Interventions: DRUG: Hydroxychloroquine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Acute Effects of a New HFNT Nasal Cannula
Status: COMPLETED
Conditions: COPD Exacerbation Acute
Interventions: DEVICE: AIRVO 2, the new asymmetric nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure
Status: UNKNOWN
Conditions: Pigmentation|Redness
Interventions: OTHER: cyclic merocyanine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing the Acute Care Burden of Childhood Asthma on Health Services in British Columbia
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Asthma
Interventions: DRUG: Arm 1 Oral Cortico Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
Status: UNKNOWN
Conditions: Alveolitis of Jaw|Alveoli, Teeth; Inflammation|Dry Socket|Impacted Third Molar Tooth
Interventions: DRUG: Iodoform|OTHER: Wound closure using sutures|DRUG: Chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Photobiomodulation for Cancer-Related Cognitive Impairment
Status: NOT_YET_RECRUITING
Conditions: Cancer-related Cognitive Impairment
Interventions: DEVICE: THOR LED Photobiomodulation Helmet - Therapeutic|DEVICE: THOR LED Photobiomodulation Helmet - Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Research Study Looking Into Blood Levels of the Medicine NNC0480-0389 in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney Function
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: NNC0480-0389
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravaginal Vibratory Stimulus and Pelvic Floor Muscle Training
Status: WITHDRAWN
Conditions: Urinary Incontinence
Interventions: OTHER: Pelvic floor muscle training (PFMT)|OTHER: Pelvic floor muscle training + intravaginal vibratory stimulus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Evaluation of 3 Bowel Preparations in the Pediatric Population
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: HalfLytely and Bisacodyl Tablets - Formulation 1|DRUG: HalfLytely and Bisacodyl Tablets - Formulation 2|DRUG: NuLYTELY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Targeted Biopsies in Determining Response in Patients With Prostate Cancer Undergoing High-Dose-Rate Brachytherapy
Status: WITHDRAWN
Conditions: Stage III Prostate Adenocarcinoma
Interventions: PROCEDURE: Biopsy of Prostate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety & Immunogenicity of HIV Vaccines in Healthy Kenyan Adults
Status: COMPLETED
Conditions: AIDS
Interventions: BIOLOGICAL: Ad35-GRIN|BIOLOGICAL: MVA.HIVconsv|BIOLOGICAL: pSG2.HIVconsv DNA|BIOLOGICAL: Electroporated pSG2.HIVconsv
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Lenacapavir in Combination With Other Antiretroviral Agents in People Living With HIV
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: Oral Lenacapavir|DRUG: F/TAF|DRUG: Subcutaneous Lenacapavir|DRUG: TAF|DRUG: BIC|DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Nutrition Education and Milk Provision in Fueling the Progress of 1 - 3 Years Old Children
Status: UNKNOWN
Conditions: Iron-deficiency
Interventions: COMBINATION_PRODUCT: Nutrition Education and Growing Up Milk for 1 - 3 years old|BEHAVIORAL: Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosuvastatin Versus Pravastatin in HIV Patients Treated With Boosted Protease Inhibitors (PI) (ANRS126)
Status: COMPLETED
Conditions: Hyperlipidemia|HIV Infections
Interventions: DRUG: Pravastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Dietary Interventions for Treating Insulin Resistance
Status: COMPLETED
Conditions: Insulin Resistance|Obesity|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Fish Oil|DIETARY_SUPPLEMENT: Polyphenol Capsules|DIETARY_SUPPLEMENT: Corn Oil Capsules|DIETARY_SUPPLEMENT: Corn starch capsules|OTHER: Reduced glycemic index bread products|OTHER: Market variety bread products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Malignant Solid Neoplasm|Recurrent Ependymal Tumor|Recurrent Ewing Sarcoma|Recurrent Glioma|Recurrent Hepatoblastoma|Recurrent Histiocytic and Dendritic Cell Neoplasm|Recurrent Langerhans Cell Histiocytosis|Recurrent Malignant Germ Cell Tumor|Recurrent Malignant Solid Neoplasm|Recurrent Medulloblastoma|Recurrent Neuroblastoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Osteosarcoma|Recurrent Peripheral Primitive Neuroectodermal Tumor|Recurrent Primary Malignant Central Nervous System Neoplasm|Recurrent Rhabdoid Tumor|Recurrent Rhabdomyosarcoma|Recurrent Soft Tissue Sarcoma|Refractory Ependymoma|Refractory Ewing Sarcoma|Refractory Glioma|Refractory Hepatoblastoma|Refractory Histiocytic and Dendritic Cell Neoplasm|Refractory Langerhans Cell Histiocytosis|Refractory Malignant Germ Cell Tumor|Refractory Malignant Solid Neoplasm|Refractory Medulloblastoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Refractory Peripheral Primitive Neuroectodermal Tumor|Refractory Primary Malignant Central Nervous System Neoplasm|Refractory Rhabdoid Tumor|Refractory Rhabdomyosarcoma|Refractory Soft Tissue Sarcoma|Wilms Tumor
Interventions: OTHER: Pharmacokinetic Study|DRUG: Ulixertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Tolerability of TAK-228 With TAK-117 and Paclitaxel in Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor
Interventions: DRUG: paclitaxel|DRUG: TAK-228|DRUG: TAK-117
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Kombucha on Blood Sugar Levels in Humans
Status: COMPLETED
Conditions: Glucose|Glucose Metabolism Disorders (Including Diabetes Mellitus)|Blood Sugar; High
Interventions: DIETARY_SUPPLEMENT: Commercial kombucha tea|DIETARY_SUPPLEMENT: Brewed kombucha tea|OTHER: Control: Tea|OTHER: Control: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Nail Psoriasis
Interventions: DEVICE: Excimer laser|DRUG: Methotrexate Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kinematic Comparison of Vanguard XP and Vanguard CR Total Knee Arthroplasties
Status: WITHDRAWN
Conditions: Osteoarthritis
Interventions: DEVICE: Total knee arthroplasty with Vanguard XP|DEVICE: Total knee arthroplasty with Vanguard CR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT