pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab in Pancreatic Cancer Patients
Status: COMPLETED
Conditions: Unresectable Pancreatic Carcinoma
Interventions: DRUG: Tocilizumab|DRUG: Gemcitabine|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Selected Responsible Fatherhood and Healthy Marriage Programs: Parents and Children Together
Status: COMPLETED
Conditions: Responsible Fatherhood|Healthy Marriage
Interventions: BEHAVIORAL: Responsible Fatherhood or Healthy Marriage Program|BEHAVIORAL: Other services in the community
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Docetaxel and Capecitabine in Treating Patients With Metastatic Cancer of the Stomach or Gastroesophageal Junction
Status: COMPLETED
Conditions: Esophageal Cancer|Gastric Cancer
Interventions: DRUG: capecitabine|DRUG: docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy of Long-acting Injectable Risperidone and Olanzapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intrathecal Rituximab in 16 Children of Stage Ⅲ、ⅣNon-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|Child, Only
Interventions: OTHER: intrathecal rituximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A High Frequency Spinal Cord Stimulation PET-CT Scan Study
Status: UNKNOWN
Conditions: Neuropathic Pain
Interventions: DEVICE: Spinal Cord Stimulation 4000Hz|DEVICE: Spinal Cord Stimulation 10000Hz|DEVICE: Spinal Cord Stimulation 40Hz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DRUG: Inersan|DRUG: Doxycycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Nebulization for Pain Control After Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Laparoscopic Cholecystectomy
Interventions: DRUG: Ropivacaine 30 mg|DRUG: Ropivacaine 30 mg|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Histological Evaluation of the Picosure 755nm Laser With Cap Array for Facial Rejuvenation
Status: COMPLETED
Conditions: Facial Rejuvenation
Interventions: DEVICE: 755nm Laser with Cap Array
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multidomain Interventions Via Face-to-face and Video Communication Platforms in Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: BEHAVIORAL: Multidomain intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients
Status: RECRUITING
Conditions: Surgery|Obesity|NASH - Nonalcoholic Steatohepatitis|Cirrhosis
Interventions: OTHER: Lifestyle therapy|PROCEDURE: Bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury
Status: TERMINATED
Conditions: Kidney Injury|Proteinuria|Hypertension
Interventions: DRUG: Isosorbide Mononitrate|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Levels in Children With IBD
Status: TERMINATED
Conditions: Inflammatory Bowel Disease|Crohn's Disease|Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: ergocalciferol|DIETARY_SUPPLEMENT: Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ahmed Glaucoma Valve Surgery With Mitomycin-C
Status: COMPLETED
Conditions: Glaucoma|Primary Open Angle Glaucoma|Secondary Glaucoma|Neovascular Glaucoma
Interventions: DRUG: Mitomycin-C|OTHER: Balanced Salt Solution|PROCEDURE: Ahmed Glaucoma Valve Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: recombinant human stem cell factor|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: etoposide|DRUG: melphalan|DRUG: mitoxantrone hydrochloride|DRUG: paclitaxel|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of Gait Training Methods in Sub-acute Stroke and Spinal Cord Injury
Status: NOT_YET_RECRUITING
Conditions: Stroke|Incomplete Spinal Cord Injury
Interventions: DEVICE: Body-weight-supported treadmill training (BWSTT)|DEVICE: EksoNR exoskeleton gait training|DEVICE: Overground gait training
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Efficacy and Safety of PreLipid® on Subjects With Higher Than Normal Blood Lipid Levels
Status: COMPLETED
Conditions: Hyperlipidemia
Interventions: DIETARY_SUPPLEMENT: Study Dietary Supplement (Prelipid 500 mg capsules)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Cognitive Behavioral Therapy for Insomnia in Young Adults With Chronic Pain
Status: WITHDRAWN
Conditions: Insomnia|Chronic Pain|Insomnia Due to Medical Condition
Interventions: OTHER: Delivering Online "ZZZ's with Empirical support (DOZE) app|OTHER: Sleep diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy of Surfaktant in Preterm Infants by Lung Ultrasound
Status: UNKNOWN
Conditions: Lung Ultrasound Scores
Interventions: DEVICE: group 1 Poractant alfa|DEVICE: group 2 beractant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reverse Trendelenburg Positioning and Its Effect on Outcomes: a Retrospective Study of Consecutive Patients
Status: COMPLETED
Conditions: Aspiration, Respiratory|Hypoxia|Perioperative Period|Supine Position
Interventions: PROCEDURE: Surgical patients in 2012 with anesthesia and nursing staff less attuned to intraoperative RTP.|PROCEDURE: Surgical patients in 2015 with enhanced anesthesia and nursing staff awareness and use of intraoperative RTP.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dosimetry Guided PRRT With 177Lu-DOTATATE in Children and Adolescents
Status: WITHDRAWN
Conditions: Neuroendocrine Tumors|Pheochromocytoma|Paraganglioma
Interventions: DRUG: 177Lu-DOTA-tyr3-OCTREOTATE|PROCEDURE: Peptide Receptor Radiotherapy (PRRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Neurofeedback Efficacy in Adults With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: OTHER: Neurofeedback|OTHER: Sham Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Scientific Exercise Approach to Scoliosis in Mild Idiopathic Scoliosis
Status: COMPLETED
Conditions: Scoliosis Idiopathic|Exercise|Quality of Life|Treatment
Interventions: OTHER: SEAS training|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase IV Clinical Trial (STAR Study) Extension Study of Conbercept Ophthalmic Injection for Treatment of Polypoid Choroidal Vasculopathy
Status: UNKNOWN
Conditions: Polypoid Choroidal Vasculopathy (PCV)
Interventions: DRUG: conbercept ophthalmic injection （0.5mg）|DRUG: conbercept ophthalmic injection （0.5mg）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comprehensive Evaluation in Patients With Meniere's Disease
Status: COMPLETED
Conditions: Meniere Disease|Psychosocial Problem|Physical Disability|Quality of Life
Interventions: OTHER: Case report form|OTHER: Tinnitus disability scale|OTHER: A feeling of fullness and/or pressure in the ear|OTHER: Dizziness intensity and frequency|OTHER: Dizziness disability inventory|OTHER: Vertigo symptom scale-short form|OTHER: Hearing Impairment Scale|OTHER: Cervical Range of Motion (CROM 3) device|OTHER: Temporomandibular joint range of motion assessment|OTHER: Posture evaluation with New York posture analysis|OTHER: Evaluation of the anterior tilt angle of the head|OTHER: Evaluation of postural balance with the Freemed pressure platform|OTHER: Static balance assessment with tandem stance test|OTHER: Dynamic balance assessment with tandem gait test|OTHER: Headache, Temporomandibular pain and Craniocervical pain presence and severity assessment|OTHER: Pain sensitivity assessment in the head, neck, shoulder girdle and upper back region|OTHER: International physical activity questionnaire-measurement of physical activity level with short|OTHER: Evaluation of sleep quality with the Pittsburgh sleep quality index|OTHER: Evaluation of fatigue with the fatigue severity scale|OTHER: Evaluation of anxiety-depression status with hospital anxiety and depression scale|OTHER: Evaluation of quality of life with short form-12 (SF-12)|OTHER: the International Fall Efficiency Scale|OTHER: assessment of muscle performance
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Motor-Sparing Femoral Nerve Block Dose
Status: TERMINATED
Conditions: Osteoarthritis, Knee|Knee Injuries
Interventions: DRUG: Same Bupivacaine Concentration|DRUG: Lower Bupivacaine Concentration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Acetylated and Butyrylated High Amylose Maize Starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm Larvae
Status: RECRUITING
Conditions: Hookworm Infection
Interventions: BIOLOGICAL: Necator americanus Hookworm Larvae
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube or Primary Peritoneal Cancer With BRCA1 or BRCA2 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: BRCA1 Gene Mutation|BRCA2 Gene Mutation|Ovarian Serous Adenocarcinoma|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma
Interventions: BIOLOGICAL: Durvalumab|OTHER: Laboratory Biomarker Analysis|DRUG: Olaparib|BIOLOGICAL: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nesiritide in Resistant Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Nesiritide (BNP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cost-effectiveness Analysis of the Single-implant Mandibular Overdenture Treatment
Status: COMPLETED
Conditions: Mouth, Edentulous
Interventions: PROCEDURE: Mandibular Overdenture|PROCEDURE: Mandibular complete denture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of Continuous Assessment of Frailty and Muscle Quality in Older Subjects: ECOFRAIL Protocol
Status: RECRUITING
Conditions: Frailty|Sarcopenia|Ultrasonography|Exercise
Interventions: OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Supplemental Oxygen on Perioperative BNP Concentration in Cardiac Risk Patients
Status: COMPLETED
Conditions: Supplemental Oxygen|Brain Natriuretic Peptide|Cardiac Risk Patients|Perioperative
Interventions: DRUG: Oxygen 30 %|DRUG: Oxygen 80 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Experimentation With Tenofovir Disoproxyl Fumarate and Emtricitabine for COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: DRUG: Vitamin C 500 MG Oral Tablet|DRUG: Tenofovir disoproxyl fumarate 300 MG Oral Tablet|DRUG: Tenofovir disoproxyl fumarate 300 MG plus emtricitabine 200 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A as Treatment for Osteoarthritis Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Status: NOT_YET_RECRUITING
Conditions: Colonic Polyp|Colon Cancer
Interventions: OTHER: Orton Score|OTHER: Typical Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) in Adult Outpatients With Major Depressive Disorder (MDD)
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: desvenlafaxine succinate sustained-release 50 mg/day|DRUG: desvenlafaxine succinate sustained-release 100 mg/day|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure (CPAP) Promotion And Prognosis - the Army Sleep Apnea Program (ASAP)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Eszopiclone|DRUG: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome
Status: RECRUITING
Conditions: Metabolic Syndrome|Menopause
Interventions: DIETARY_SUPPLEMENT: L-Citrulline supplementation|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Reperfusion With Hypothermia in Acute Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke|Revascularization|Endovascular Treatment|Reperfusion Injury
Interventions: DEVICE: Thermogard XP3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Probiotics at the Treatment of Antibiotic Associated Diarrhea
Status: COMPLETED
Conditions: Antibiotic-Associated Diarrhea
Interventions: DIETARY_SUPPLEMENT: Probiotics - Lactobacillus casei and Bifidobacterium breve|DIETARY_SUPPLEMENT: Maize starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-based Family-centered Empowerment Program for Heart Failure (T-FAME-HF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Telerehabilitation|Self Care|Empowerment|Disease Management
Interventions: OTHER: T-FAME-HF|OTHER: Control group - HF education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Status: SUSPENDED
Conditions: Neoplasms|Solid Tumors
Interventions: DRUG: TdCyd
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kidney and Blood Stem Cell Transplantation That Eliminates Requirement for Immunosuppressive Drugs
Status: ACTIVE_NOT_RECRUITING
Conditions: Immune Tolerance
Interventions: BIOLOGICAL: Hematopoietic cell transplantation|RADIATION: Total lymphoid irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facial Expression Recognition of Emotion and Categorization of Emotional Words in Parkinson's Disease. Impact of L-Dopa and Deep Brain Stimulation of Subthalamic Nucleus
Status: COMPLETED
Conditions: Idiopathic Parkinson's Disease
Interventions: BEHAVIORAL: Facial expression recognition of emotion|BEHAVIORAL: Facial expression recognition of emotion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Extended-infusion of Piperacillin-Tazobactam Versus Intermittent Infusion
Status: COMPLETED
Conditions: Gram-Negative Infections
Interventions: DRUG: Piperacillin/Tazobactam Continuous infusion|DRUG: Piperacillin/Tazobactam Intermittent infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of Fasting in Fertility Treatment
Status: COMPLETED
Conditions: Sub Fertility, Female|Fertility Disorders|Cycle Disorders Menstrual|Ovulation Disorder|Ovulation Absent|Ovulation Delayed|Ovulation; Failure or Lack of|Sub-fertility
Interventions: BEHAVIORAL: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Novel Exergame-Based Training Concept for Older Adults With Mild Neurocognitive Disorder
Status: COMPLETED
Conditions: Mild Neurocognitive Disorder
Interventions: BEHAVIORAL: Exergame training according to the 'Brain-IT' exergame-based training concept|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Network Dysfunction, Schizophrenia and Pharmacological Magnetic Resonance Imaging (phMRI)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Esketamine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Wet Cupping Therapy on Headache and Migraine-related Disability
Status: NOT_YET_RECRUITING
Conditions: Migraine-related Headache
Interventions: OTHER: Wet Cupping|OTHER: No intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anecortave Acetate Risk Reduction Trial (AART)
Status: TERMINATED
Conditions: AMD
Interventions: DRUG: Anecortave Acetate Sterile Suspension, 30 mg/mL|DRUG: Anecortave Acetate Sterile Suspension, 60 mg/mL|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Duloxetine in Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Duloxetine 60 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Internet-based Positive Psychological Intervention for Hispanic/Latino Adult With Hypertension in a Primary Care Setting
Status: UNKNOWN
Conditions: Uncontrolled Hypertension|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Internet-based Positive Psychological Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of OSTAP, ESP Block,Injection of Local Anesthetic to Trocar Insertion for Elective Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain|Regional Anesthesia
Interventions: PROCEDURE: Unilateral ESP Block|PROCEDURE: Unilateral OSTAP Block|PROCEDURE: Injection of Local Anesthetic to Trocar Insertion|DRUG: intravenous patient controlled analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly 70 mg/m2 Carfilzomib for Multiple Myeloma Patients Refractory to 27 mg/m2 Carfilzomib
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone|DRUG: Prednisone|DRUG: Methylprednisolone|DRUG: Lenalidomide|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupressure on Constipation in Community-dwelling Spinal Cord Injury Patients: A Randomized Controlled Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Traditional Chinese Medicine
Interventions: OTHER: Home-based, acupressure combined with nursing education|OTHER: Home-based, manual light touch of the abdomen combined with nursing education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM)
Status: RECRUITING
Conditions: Glioblastoma Multiforme|Glioblastoma Multiforme, Adult|Supratentorial Glioblastoma|Supratentorial Gliosarcoma
Interventions: BIOLOGICAL: P140K-MGMT|DRUG: O6-benzylguanine|RADIATION: Photon Based Radiotherapy|DRUG: temozolomide|DRUG: Filgrastim|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of High Dosage of Losartan in Comparison to Low Dose of Losartan in Heart Failure Patients
Status: WITHDRAWN
Conditions: Heart Failure
Interventions: DRUG: Low dose losartan|DRUG: High dose losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient Utilization of Opioid Destruction Bags in the Post op Period
Status: ENROLLING_BY_INVITATION
Conditions: Opioid Use|Opioid Use, Unspecified|Patient Empowerment|Total Knee Arthoplasty|Total Hip Arthroplasty
Interventions: BEHAVIORAL: Opioid destruction education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Lidocaine Infusion Treatment in Management of Neuropathic Pain
Status: UNKNOWN
Conditions: Postherpetic Neuralgia|Diabetic Polyneuropathy|Peripheral Neuropathy
Interventions: DRUG: Lidocaine HCl|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Colesevelam for Lenalidomide-Associated Diarrhea
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma|Diarrhea
Interventions: DRUG: Colesevelam Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Response and Oxidative Stress in Cardiac Surgery: Min. Invasive vs. Conventional Extracorporeal Circulation
Status: NOT_YET_RECRUITING
Conditions: Oxidative Stress|Systemic Inflammatory Response Syndrome|Extracorporeal Circulation; Complications
Interventions: PROCEDURE: Minimally Invasive Extracorporeal Circulation|PROCEDURE: Conventional Extracorporeal Circulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pilot Study of PUFA-optimized RUTF for Severe Acute Malnutrition
Status: COMPLETED
Conditions: Kwashiorkor|Marasmus
Interventions: DIETARY_SUPPLEMENT: RUTF|DIETARY_SUPPLEMENT: RUTF-P|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Root Caries Prevention Using Fluoride Varnish Fortified With SBGC
Status: RECRUITING
Conditions: Dental Caries of Root Surface|Root Caries
Interventions: COMBINATION_PRODUCT: Fluoride varnish with SBGC|DRUG: Fluoride varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Supporting Social and Emotional Competence in Preschool Children
Status: COMPLETED
Conditions: Children's Social Emotional Competence|Children's Well-being
Interventions: BEHAVIORAL: Promoting Alternative Thinking Strategies (PATHS), Preschool Edition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of Vertical Implant Position With Immediate Provisionalization on the Marginal Bone Loss.
Status: NOT_YET_RECRUITING
Conditions: Dental Implant Failed|Implant Site Reaction
Interventions: PROCEDURE: Sub-crestal implant|PROCEDURE: Equi-crestal implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
Status: RECRUITING
Conditions: Limited-Stage Small Cell Lung Cancer
Interventions: DRUG: HLX10|DRUG: carboplatin/cisplatin-etoposide|RADIATION: Thoracic radiotherapy|DRUG: Placebo|RADIATION: Prophylactic Cranial Irradiation (PCI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy and Safety of an Anti-Allergy Drug With a Contact Lens in Allergic Conjunctivitis
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Ketotifen with a Contact Lens (generic name not yet established)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: SHR-A1811 in Combination With Adebrelimab for the Treatment of HER2 Low-expressing Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: SHR-A1811+Adebrelimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MesoTRAP: A Study Comparing Video-assisted Thoracoscopic Partial Pleurectomy/Decortication With Indwelling Pleural Catheter in Patients With Trapped Lung Due to Malignant Pleural Mesothelioma.
Status: COMPLETED
Conditions: Malignant Pleural Mesothelioma|Trapped Lung
Interventions: PROCEDURE: pleurectomy/decortication|PROCEDURE: indwelling pleural catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Regulation - Role of Potassium
Status: COMPLETED
Conditions: Blood Pressure|Hypertension
Interventions: DRUG: Kaleorid, 750mg (trade name), Potassium chloride (active substance)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Assess the Safety, Tolerability, Pharmacokinetics and Immunogenicity of AK006 in Healthy Subjects and Subjects With Chronic Spontaneous Urticaria
Status: RECRUITING
Conditions: Healthy Participants|Chronic Spontaneous Urticaria
Interventions: DRUG: AK006-IV|DRUG: Placebo-IV|DRUG: AK006-SC|DRUG: Placebo-SC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Knowledge Translation and Exercise for Degenerative Meniscal Tears and Early Osteoarthritis: KNEE-DEeP Study
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Meniscus; Degeneration
Interventions: OTHER: KNEE-DEeP intervention- Knowledge translation and exercise for early degenerative knee pain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: RELAX Anaesthetics: the Effect of a Bespoke Relaxation App on Stress Levels in Children Undergoing Anaesthesia
Status: COMPLETED
Conditions: Surgery
Interventions: OTHER: iPad app containing art, music and games|OTHER: Toys, books and games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pecto-Intercostal Fascial Block Versus Transversus Thoracic Muscle Plane Block in Cardiac Surgery
Status: UNKNOWN
Conditions: Pecto-Intercostal Fascial Block|Transversus Thoracis Muscle Plane Block|Cardiac Surgery|Postoperative Analgesia
Interventions: PROCEDURE: Pecto-Intercostal Fascial Block|PROCEDURE: Transversus Thoracis Muscle Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Intranasal Live Attenuated Influenza Vaccine Immunogenicity and Associations With the Nasopharyngeal Microbiome Among Children in the Gambia
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Nasovac-S|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Yearly Strain Variation Study, 2009/2010
Status: COMPLETED
Conditions: Influenza|Seasonal Influenza
Interventions: BIOLOGICAL: Preflucel [Trivalent seasonal influenza vaccine (split virus, Vero cell-derived)]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Hormonal Intrauterine Device in Treating PCS Compared to Oral Progestin
Status: COMPLETED
Conditions: Pelvic Congestion
Interventions: DEVICE: Hormonal intrauterine device|DRUG: Progestins Norethindrone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Multicenter Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Decision Counseling Program in Increasing Shared Decision Making and Clinical Trial Participation in Patients With Stage 0-IV Lung Cancer (Free to Breathe)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: Educational Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Patients
Status: COMPLETED
Conditions: Hypoxia|SARS-CoV-2 Acute Respiratory Disease|Carotid Bodies
Interventions: DIAGNOSTIC_TEST: Phase-1: Breath Holding Test|DIAGNOSTIC_TEST: Phase 2: 6-Minute Walk Test (6MWT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin K2 Supplementation in Adult Episodic Migraine
Status: NOT_YET_RECRUITING
Conditions: Migraine Headache|Arterial Stiffness|Vitamin K Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin K2 or menaquinone-7|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Method Validation Study to Explore the Sensitivity of SenseWear Armband Gecko for Measuring Physical Activity in Subjects With Chronic Obstructive Pulmonary Disease (COPD) & Asthma
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DEVICE: SenseWear Armband Gecko|DEVICE: SenseWear Armband MF|DEVICE: Actigraph GT9x wristband and waistband|DEVICE: Garmin Vivofit 2 wristband|DEVICE: SOMNOwatch plus EEG 6 sleep monitor|OTHER: Strength exercises|OTHER: Field-based exercise tests|OTHER: Laboratory-based exercise tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Shockwave Therapy Versus Radiofrequency
Status: COMPLETED
Conditions: Cardiovascular Risk Factor|Metabolic Disease|Photoaging
Interventions: DEVICE: Radiofrequency|DEVICE: Aerobic exercise|DEVICE: Shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Status: RECRUITING
Conditions: Autoimmune Diseases|Autoimmune Diseases of the Nervous System|Neuromyelitis Optica Spectrum Disorder|Myasthenia Gravis|Chronic Inflammatory Demyelinating Polyradiculoneuropathy|Idiopathic Inflammatory Myopathies|Multiple Sclerosis|Autoimmune Encephalitis|Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)|POEMS Syndrome
Interventions: BIOLOGICAL: CT103A cells|DRUG: Cyclophosphamide and fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BAY2586116 Nasal Spray and OSA Severity
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive
Interventions: DRUG: BAY2586116|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Optional IVC Filters Regardind Ease of Use,Complications and Outcome
Status: UNKNOWN
Conditions: Trauma|Deep Vein Thrombosis
Interventions: DEVICE: Optease IVC filters|DEVICE: Gunter-Tulip IVC filters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Constraint-Induced Movement Therapy and Action Observation Training in Children With Unilateral Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: BEHAVIORAL: Constraint-induced movement therapy|BEHAVIORAL: Action observation training|BEHAVIORAL: Placebo observation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Misoprostol on Blood Loss In Myomectomy Operations
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Misoprostol|DRUG: Placebo( for misoprostol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence Study to Compare Chenodeoxycholic Acid Capsules (250mg Chenodeoxycholic Acid) Versus Chenodeoxycholic Acid Leadiant 250 mg Hard Capsules (250mg Chenodeoxycholic Acid)
Status: COMPLETED
Conditions: Cerebrotendinous Xanthomatoses
Interventions: DRUG: Chenodeoxycholic acid|DRUG: Chenodeoxycholic acid leadiant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
Status: COMPLETED
Conditions: Stable Angina|Unstable Angina|Non-ST Segment Elevation Myocardial Infarction
Interventions: DRUG: 3-months DAPT|DRUG: 1-year DAPT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sirolimus-Eluting Stent vs. Intravascular Brachytherapy in In-Stent Restenotic Coronary Artery Lesions(SISR)
Status: COMPLETED
Conditions: In-Stent Restenosis
Interventions: DEVICE: Sirolimus-Eluting Bx Velocity® Balloon Expandable Stent|PROCEDURE: Brachytherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Crocin Supplementation on Metabolic Parameters, Oxidative Stress, AMP- Activated Protein Kinase and Inflammation-promoting Genes Expression in Peripheral Blood Mononuclear Cells in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: crocin|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Status: NOT_YET_RECRUITING
Conditions: B Acute Lymphoblastic Leukemia
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: Blinatumomab|PROCEDURE: Bone Marrow Biopsy|DRUG: Calaspargase Pegol|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dasatinib|DRUG: Daunorubicin|DRUG: Doxorubicin|PROCEDURE: Echocardiography|DRUG: Leucovorin|DRUG: Mercaptopurine|DRUG: Methotrexate|PROCEDURE: Multigated Acquisition Scan|DRUG: Pegaspargase|DRUG: Prednisolone|DRUG: Prednisone|RADIATION: Radiation Therapy|DRUG: Thioguanine|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilonidal Sinus Disease: Preliminare Study
Status: COMPLETED
Conditions: Pilonidal Sinus
Interventions: PROCEDURE: In "hot" group 16 patients were treated by diathermy in "Cold"|PROCEDURE: in "Cold" group 13 patients were treated by scalpel.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomized Phase 2 Study of Ixabepilone Plus Carboplatin and Paclitaxel Plus Carboplatin in Advanced Nonsmall-Cell Lung Cancer
Status: COMPLETED
Conditions: Advanced/Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: Ixabepilone, 32 mg/m^2|DRUG: Paclitaxel, 200 mg/m^2|DRUG: Carboplatin (area under the concentration curve [AUC] 6)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy Volunteers to Assess the Tolerability and Blood Levels of a Single Dose of AZD7687
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD7687|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Seroma Reduction After Mastectomy
Status: COMPLETED
Conditions: Seroma|Aspiration|Breast Cancer
Interventions: DRUG: Artiss|PROCEDURE: vicryl sutures|PROCEDURE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Waterproof Casting Versus Standard Casting for Short Leg Walking Casts
Status: NOT_YET_RECRUITING
Conditions: Ankle Fractures|Foot Fracture|Ankle Sprains|Foot Sprain|Toe-walking|Tendonitis of Foot|Apophysitis; Juvenile
Interventions: DEVICE: Waterproof padding|DEVICE: Non-waterproof padding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study
Status: COMPLETED
Conditions: Sick Sinus Syndrome
Interventions: OTHER: Ventricular Pace Suppression (Vps)|OTHER: Intrinsic rhythm support (IRSplus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing a Novel Stress-induced Eating Intervention for Cancer Prevention
Status: WITHDRAWN
Conditions: 7-dose Control - Progressive Muscle Relaxation Only|5-dose - Pairs Progressive Muscle Relaxation With Fruit 5 Consecutive Days|7-dose - Pairs Progressive Muscle Relaxation With Fruit 7 Consecutive Days|9-dose - Pairs Progressive Muscle Relaxation With Fruit 9 Consecutive Days
Interventions: BEHAVIORAL: Pavlovian Conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas
Status: COMPLETED
Conditions: Neurofibromatosis 2|Meningioma
Interventions: DRUG: AZD2014
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan
Status: RECRUITING
Conditions: Sarcoma
Interventions: OTHER: Surveys|OTHER: Blood Collection|OTHER: Saliva Collection|OTHER: Urine Collection|OTHER: Stool Collection|OTHER: Tissue collection|OTHER: Physical Activity Monitoring
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Anterior Cruciate Ligament Injury
Interventions: DEVICE: Neuromuscular Electrical Stimulation (NMES)|OTHER: Eccentric Exercise (ECC)|DEVICE: Neuromuscular Electrical Stimulation (NMES) placebo|OTHER: Eccentric Exercise (ECC) placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Open Label Study Evaluating Two Management Strategies on Gastrointestinal Symptoms in Patients Newly on Treatment With Pradaxa for the Prevention of Stroke and Systemic Embolism With Non-valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: pantoprazole|DRUG: Pradaxa (dabigatran etexilate)|DRUG: Pradaxa, within 30 minutes after a meal|DRUG: Pradaxa (dabigatran etexilate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Surgical Removal of Idiopathic Epiretinal Membrane With and Without the Assistance of Indocyanine Green.
Status: COMPLETED
Conditions: Idiopathic Epiretinal Membrane, Cataract
Interventions: DRUG: Surgery with and without the aid of Indocyanine Green (ICG)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Managing Infliximab Reinduction After Temporary Discontinuation of Drug
Status: WITHDRAWN
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: Infliximab at weeks 0,2, and 6|DRUG: Infliximab at weeks 0,4, and 8|DRUG: Infliximab at weeks 0 and 8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Fampridine on Working Memory in Healthy Young Subjects
Status: COMPLETED
Conditions: Working Memory
Interventions: DRUG: Fampridine SR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical or Catheter Ablation of Lone Atrial Fibrillation (AF) Patients
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter Ablation|PROCEDURE: Surgical Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT