pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Building Resiliency Among Caregivers of Curvivors and Metavivors
Status: RECRUITING
Conditions: Stress|Cancer Diagnosis|Distress, Emotional
Interventions: BEHAVIORAL: Smart-3RP|BEHAVIORAL: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Time Effects of a Berry Extract Upon Cerebral Blood Flow.
Status: COMPLETED
Conditions: Cerebral Blood Flow
Interventions: DIETARY_SUPPLEMENT: Berry drink|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Fenretinide in Treating Patients With Refractory or Relapsed Hematologic Cancer
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: fenretinide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
Status: COMPLETED
Conditions: Type 2 Diabetes (Treated With Exenatide or Other Oral Antidiabetic Therapies)|Healthy Subjects (Treated With no Diabetes Therapies)
Interventions: DRUG: exenatide|DRUG: Other antidiabetic therapies|OTHER: No diabetes therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Saline Lavage X Saline Lavage and Osteonil® Mini in Rizarthritis
Status: UNKNOWN
Conditions: Rhizarthrosis|Metabolic Disease
Interventions: BEHAVIORAL: Visual Analog Scale (VAS)|BEHAVIORAL: Range of Motion (ROM)|BEHAVIORAL: Palmar grip strength|BEHAVIORAL: Lateral grip strength|BEHAVIORAL: Pulp-pulp pinch strength|DRUG: Lavage with physiologic saline solution|DRUG: Lavage with physiologic saline solution and Osteonil® Mini|BEHAVIORAL: Quick Dash|BEHAVIORAL: Sollerman Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous Leukemia
Interventions: DRUG: Dasatinib|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MMP-9 Inhibition for Recalcitrant Wet AMD
Status: RECRUITING
Conditions: Exudative Macular Degeneration|Wet Age-related Macular Degeneration
Interventions: DRUG: Doxycycline Hyclate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adipose Tissue Injection for the Treatment of Complex Cryptoglandular Perianal Fistula
Status: RECRUITING
Conditions: Anal Fistula
Interventions: PROCEDURE: Injection of autologous freshly collected adipose tissue|PROCEDURE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion
Status: SUSPENDED
Conditions: Abortion in First Trimester
Interventions: DRUG: PO Morphine|DRUG: IV Fentanyl|DRUG: IV Ketamine|DRUG: PO Placebo|DRUG: IV Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization
Status: ENROLLING_BY_INVITATION
Conditions: Atrial Fibrillation and Flutter|Hyperthyroidism|Hypothyroidism
Interventions: PROCEDURE: Catheter Ablation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combination Chemotherapy and Radiation Therapy in Treating Patients Who Are Undergoing an Autologous Stem Cell Transplant for Relapsed or Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: carboplatin|DRUG: etoposide|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy
Status: COMPLETED
Conditions: Vaginal Vault Prolapse
Interventions: DEVICE: Vertessa® Lite Y mesh|DEVICE: Restorelle® Y mesh|PROCEDURE: Laparoscopic sacrocolpopexy|PROCEDURE: Robotic assisted laparoscopic sacrocolpopexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Injections of rhuFab V2 in Combination With Visudyne in Subjects With Age Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Age-Related Maculopathy
Interventions: DRUG: rhuFab V2 (ranibizumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Electromagnetic Field in Lumbar Disc Prolapse Patients
Status: RECRUITING
Conditions: Lumbar Disc Herniation
Interventions: DEVICE: electromagnetic field therapy|OTHER: selected physical therapy program|DEVICE: Therapeutic ultrasound therapy|DEVICE: Transcutaneous Electrical Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or Overweight
Status: RECRUITING
Conditions: Obesity|Overweight and Obesity
Interventions: DRUG: LY3841136|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of TF3 and TF2 and Effect of Food on the PK of Tepotinib
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tepotinib TF2|DRUG: Tepotinib TF3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SLEep APnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke
Status: COMPLETED
Conditions: Stroke|Transient Ischemic Attack|Obstructive Sleep Apnea
Interventions: DEVICE: Portable sleep monitor (ApneaLink Air)|DEVICE: In-laboratory polysomnography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation
Status: ACTIVE_NOT_RECRUITING
Conditions: Pregnancy|Child Development
Interventions: DIETARY_SUPPLEMENT: DHA|DIETARY_SUPPLEMENT: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases
Status: COMPLETED
Conditions: Mumps|Varicella|Rubella|Measles
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Chickenpox (live vaccine)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of HR19042 Capsules in the Treatment of Primary IgA Nephropathy.
Status: UNKNOWN
Conditions: IgA Nephropathy
Interventions: DRUG: HR19042 Capsules|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PeRiopEratiVE smokiNg cessaTion Trial
Status: RECRUITING
Conditions: Smoking (Tobacco) Addiction|Smoking Cessation
Interventions: DRUG: Cytisine|BEHAVIORAL: Video Messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug and Talk Therapy for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: CBT and milnacipran|BEHAVIORAL: CBT with a placebo|DRUG: Educational with milnacipran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stapled and Hand-Sewn Sleeve Gastrectomy
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Hand-Sewn Sleeve Gastrectomy|PROCEDURE: Stapled Sleeve Gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Standard Patient Simulation Method in Communication With Intensive Care Patients
Status: NOT_YET_RECRUITING
Conditions: Satisfaction|Communication|Confidence, Self
Interventions: OTHER: Standardized Simülation Patient
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Analysis of Hospitalizations One Year After Acts of CAG and PCI in the Aquitaine région - ACIRA Register Data Analysis
Status: COMPLETED
Conditions: Angioplasty|Coronary Angiography
Interventions: PROCEDURE: Percutaneous coronary intervention|PROCEDURE: Coronary angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2015_03
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Hearing Aid (Phonak Audéo V90-13)|DEVICE: Hearing Aid (Successor of Phonak Audéo V90-13)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of D-serine in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: D-serine|DRUG: D-serine|DRUG: D-serine|DRUG: D-serine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
Status: COMPLETED
Conditions: Postoperative Pain|Peripheral Neuropathy|Fractures of the Upper Limb|Fracture of the Lower Limb (Except Hip), Initial Encounter|Intraoperative Hypotension|Intraoperative Hypertension|Pain Syndrome|Anesthesia|Anesthesia, Local|Local Anesthetic Systemic Toxicity
Interventions: DRUG: Bupivacaine, dexamethasone, epinephrine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CISH Inactivated TILs in the Treatment of NSCLC
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung|Metastatic Non Small Cell Lung Cancer|Stage IV Non-small Cell Lung Cancer|Squamous Cell Lung Cancer|Adenocarcinoma of Lung|Large Cell Lung Cancer
Interventions: DRUG: Fludarabine|DRUG: Cyclophosphamide|BIOLOGICAL: CISH Inactivated TIL|DRUG: Aldesleukin|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis
Status: COMPLETED
Conditions: Vernal Keratoconjunctivitis
Interventions: DRUG: Cyclosporine A 0,05% eye drop|DRUG: ketotifen fumarate 0.025% eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Lurasidone After Multiple Oral Administration in Healthy Human Subjects
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: 40mg lurasidone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Haploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia, Acute Lymphocytic (ALL)|Leukemia, Myeloid, Acute(AML)|Leukemia, Myeloid, Chronic(CML)|Juvenile Myelomonocytic Leukemia(JMML)|Hemoglobinuria, Paroxysmal Nocturnal (PNH)|Lymphoma, Non-Hodgkin (NHL)|Myelodysplastic Syndrome (MDS)
Interventions: DEVICE: Miltenyi Biotec CliniMACS|PROCEDURE: Stem Cell Transplantation|DRUG: TBI, systemic chemotherapy and antibodies as follows:
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Electronic Cigarette Flavors on Abuse Liability in Smokers (P3-Taste)
Status: COMPLETED
Conditions: Electronic Cigarette Use
Interventions: OTHER: Tobacco product administration and assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Dietary Nitrate Supplementation on Linear Running Sprint Performance, Agility and Vertical Jump Performance in a Rested and Fatigued State
Status: COMPLETED
Conditions: Exercise Performance
Interventions: OTHER: Beetroot|OTHER: Placebo beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of a Novel Multicomponent Meningococcal Group B Vaccine When Given Alone or With Other Licensed Vaccines in Adults, Adolescents, Toddlers and Infants
Status: TERMINATED
Conditions: Meningococcal Immunisation|Healthy Volunteers
Interventions: DRUG: Multicomponent Meningococcal B Vaccine|DRUG: Meningococcal Group B Vaccine MenB|DRUG: Meningococcal Group B Vaccine (recombinant deoxyribonucleic acid [rDNA], component, adsorbed)|DRUG: Placebo|DRUG: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine MenACYW conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radioimmunotherapy With 90Y Zevalin for Orbital Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Lymphoma
Interventions: DRUG: Rituximab|DRUG: Zevalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study To Test The Safety and Efficacy of TVI-Brain-1 As A Treatment For Recurrent Grade IV Glioma
Status: COMPLETED
Conditions: Glioma|High Grade Astrocytoma|Glioblastoma Multiforme
Interventions: BIOLOGICAL: Cancer vaccine plus immune adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Bioabsorbable and Steel Screw for the Treatment of Hallux Valgus With Chevron Osteotomy
Status: UNKNOWN
Conditions: Hallux Valgus
Interventions: DEVICE: bioabsorbable screws|DEVICE: steel screws
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Nasal Septal Surgery on Sleep Quality, Daytime and Dream Anxiety
Status: COMPLETED
Conditions: Nasal Septal Deviation
Interventions: PROCEDURE: The active anterior rhinomanometry|BEHAVIORAL: The Pittsburgh Sleep Quality Index (PSQI)|BEHAVIORAL: The Beck Anxiety Inventory (BAI)|BEHAVIORAL: The Van Dream Anxiety Scale (VDAS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome
Status: COMPLETED
Conditions: Interstitial Cystitis
Interventions: DRUG: LP-08 80mg|DRUG: Normal saline|DRUG: LP-08 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Sivelestat Sodium and Dexamethasone in the Treatment of ARDS
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Sivelestat sodium|DRUG: Dexamethasone|DRUG: Sivelestat sodium placebo|DRUG: Dexamethasone placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The PATCH Trial (Prevention And Treatment of COVID-19 With Hydroxychloroquine)
Status: TERMINATED
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine Sulfate 400 mg twice a day|DRUG: Hydroxychloroquine Sulfate 600 mg twice a day|DRUG: Hydroxychloroquine Sulfate 600 mg once a day|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open and Endovascular Surgical Treatment for Artery Injuries
Status: RECRUITING
Conditions: Artery Injury
Interventions: PROCEDURE: Endovascular treatment|PROCEDURE: Open surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Artesunate-amodiaquine|DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etokimab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: BIOLOGICAL: Etokimab|BIOLOGICAL: Placebo|DRUG: Mometasone Furoate Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Novel Device for Treatment of Migraine Headache
Status: COMPLETED
Conditions: Migraine Without Aura|Migraine With Aura
Interventions: DEVICE: Nerivio Migra-1 active device|DEVICE: Nerivio Migra-1 Sham device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Intersectional Short Pulse Stimulation for Terminating Seizures
Status: NOT_YET_RECRUITING
Conditions: Seizures|Focal Epilepsy
Interventions: DEVICE: SeizureStop Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Inflammation Using Salsalate in CardioVascular Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Overweight
Interventions: DRUG: Salsalate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Biliary Tract Carcinoma|Cholangiocarcinoma
Interventions: DRUG: Pemigatinib and Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Pediatric Craniopharyngioma by a Combination of Partial Surgical Resection, and Protontherapy (Craniopharyngioma)
Status: COMPLETED
Conditions: Craniopharyngioma
Interventions: RADIATION: Protontherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical FK506 (Tacrolimus) for Prevention of Immune Reactions Following Penetrating Keratoplasty
Status: TERMINATED
Conditions: Penetrating Keratoplasty
Interventions: DRUG: FK506 0.06% (eye drops)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: PREVENTION
Clinical trial: Hydroxychloroquine for the First Thrombosis Prevention in Antiphospholipid Antibody Positive Patients
Status: TERMINATED
Conditions: Antiphospholipid Syndrome
Interventions: DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer
Status: COMPLETED
Conditions: Hot Flashes|Prostate Cancer
Interventions: DRUG: cyproterone acetate|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of Coloured Overlays and Lenses for Reading Difficulty
Status: COMPLETED
Conditions: Vision Disorders|Reading Disabilities
Interventions: DEVICE: Precision tinted lenses|DEVICE: Non-beneficial tinted lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe Atopic Dermatitis (SIGNAL-AD)
Status: RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: ADX-914|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Integration Between Learning, Body and Emotions (I-ACE)
Status: RECRUITING
Conditions: Burnout, Professional|Dementia|Quality of Life
Interventions: BEHAVIORAL: I-ACE training|OTHER: Standard non-pharmacological therapies (NPT) training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC)
Status: COMPLETED
Conditions: Carcinoma, Renal Cell
Interventions: DRUG: foretinib (formerly GSK1363089 or XL880)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Sub-mucosal Dissection With the Nestis® Jet Injector System With a Bi-functional Catheter: First Prospective Trial
Status: COMPLETED
Conditions: Barrett's Esophagus|Intestinal Dysplasia|Esophageal Dysplasia|Colorectal Neoplasms
Interventions: DEVICE: Nestis® jet injector system with a bi-functional catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: ICL670
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pulsed Electromagnetic Field (PEMF) on Human Peri-implant Tissues
Status: COMPLETED
Conditions: Periodontitis|Dental Plaque
Interventions: PROCEDURE: PEMF and Control/Sham|DEVICE: PEMF and without PEMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Ranging Study to Evaluate the Efficacy and Safety of SAR153191 (REGN88) in Patients With Ankylosing Spondylitis
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Sarilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Navigated Transcranial Magnetic Stimulation (nTMS) in the Inhibition of Neurofunctional Regions of Interest
Status: SUSPENDED
Conditions: Brain Tumor|Surgery
Interventions: DEVICE: Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Internet-delivered Psychological Interventions for Tinnitus
Status: ACTIVE_NOT_RECRUITING
Conditions: Tinnitus|Distress, Emotional|Depression, Anxiety|Sleep
Interventions: BEHAVIORAL: Internet-delivered cognitive behavioral therapy (iCBT)|BEHAVIORAL: Internet-delivered mindfulness-based tinnitus stress reduction (iMBTSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer
Status: COMPLETED
Conditions: Hormone-Resistant Prostate Cancer|Prostate Adenocarcinoma|Recurrent Prostate Carcinoma|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: Cixutumumab|OTHER: Diagnostic Laboratory Biomarker Analysis|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Psychoeducation Based on NSM on the Psychological Distress and Coping of the Spouses of Patients in ICU
Status: COMPLETED
Conditions: Psychological Distress|Stress, Psychological
Interventions: BEHAVIORAL: The stress management psychoeducation program based on Neuman's Systems Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCA for CRRT in Hyperlactatemia Patient With Increased Bleeding Risk
Status: UNKNOWN
Conditions: Continuous Renal Replacement Therapy|Hyperlactatemia|Bleeding
Interventions: PROCEDURE: Regional citrate anticoagulation CRRT|PROCEDURE: No-anticoagulation CRRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
Status: RECRUITING
Conditions: Hydrocephalus|Alzheimer Disease
Interventions: OTHER: MRI screening form|DIAGNOSTIC_TEST: Urine pregnancy test|DIAGNOSTIC_TEST: MR brain
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Endothelial Protection in Convalescent COVID-19 Patients
Status: UNKNOWN
Conditions: Endothelial Dysfunction|Inflammation|Thrombosis|COVID-19
Interventions: DRUG: Sulodexide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: AST-301(pNGVL3-hICD)|DRUG: rhuGM-CSF|DRUG: Placebo|DRUG: Pembrolizumab|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tailored Music Therapy for Dementia
Status: COMPLETED
Conditions: Alzheimer Dementia|Dementia, Vascular|Dementia, Lewy Body|Dementia Parkinson's Disease
Interventions: BEHAVIORAL: Resource oriented music therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Marwo-D Research -Need for Vitamin D in Different Population Groups
Status: COMPLETED
Conditions: Serum 25-hydroxyvitamin D Concentrations (25OHD)
Interventions: DIETARY_SUPPLEMENT: Vitamin D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Docosahexaenoic Acid (DHA) Supplementation During Pregnancy Reduces the Risk of Preterm Birth in Threatened Preterm Labor
Status: NOT_YET_RECRUITING
Conditions: Pregnant Women Diagnosed With Threatened Preterm Labor
Interventions: DIETARY_SUPPLEMENT: Docosahexaenoic acid (DHA) 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Nutritional Status and Blood Lipid Profile by Using MCT Oil on Overweight and Obese Women
Status: COMPLETED
Conditions: Obesity Adult Onset|Lipid Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: Soya bean oil|DIETARY_SUPPLEMENT: MCT oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Use of Cyclosporine Ophthalmic Emulsion 0.05% on Application of PROSE Devices for Management of Patients With Ocular Surface Disease
Status: COMPLETED
Conditions: Ocular Surface Disease
Interventions: DRUG: Restasis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacokinetics , Safety, Tolerability and Pharmacodynamics of Biocon Insulin Tregopil
Status: TERMINATED
Conditions: Type 1 Diabetes Mellitus (T1DM)
Interventions: DRUG: Tregopil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Electrophysiological Effects of Guanfacine Extended Release in Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: Guanfacine Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Tazemetostat in Newly Diagnosed Diffuse Large B Cell and Follicular Lymphoma Patients Treated by Chemiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphoma|DLBCL|Follicular Lymphoma
Interventions: DRUG: Tazemetostat|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects Of GW679769 On Sleep Onset And Maintenance And Next Day Functioning In Subjects With Primary Insomnia
Status: COMPLETED
Conditions: Sleep Initiation and Maintenance Disorders|Insomnia
Interventions: DRUG: GW679769
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Impact of Persistent Conductances on Motor Unit Firing in SCI
Status: UNKNOWN
Conditions: Chronic Spinal Cord Injury
Interventions: DRUG: sugar pill|DRUG: Riluzole|DRUG: Isradipine|DRUG: Memantine|PROCEDURE: Therapeutic muscle stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness or Orthopedic Intervention in Osteoporosis Management After a Fracture of the Hip With Cost-Benefit Analysis
Status: COMPLETED
Conditions: Osteoporotic Fracture
Interventions: PROCEDURE: Letter Group|PROCEDURE: Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1), a Topical Ophthalmic Drug for Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: PresbiDrops (CSF-1)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Liraglutide on Glucose Profiles and Gastric Emptying in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Valganciclovir Versus Ganciclovir in Patients Following Allogeneic Stem Cell Transplantation
Status: TERMINATED
Conditions: Allogeneic Stem Cell Transplantation
Interventions: DRUG: Valganciclovir|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Auditory Functions in Patients With Migraine
Status: UNKNOWN
Conditions: Migraine
Interventions: DIAGNOSTIC_TEST: Duration Pattern test (DPT) /Dichotic Digits Test (DDT) /Auditory fusion test-revised (ART-R)/|DEVICE: Dual band pure tone audiometer (Orbiter 992). -Impedance audiometer (AT 235h). -Sound treated booth (industrial acoustic company IAC model 1602-A-t) -Panasonic stereo CD player SA-AK 240.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Osteopathic Bowel Techniques and Their Effects on the Autonomic Nervous System in Healthy Individuals
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Visceral Osteopathic Techniques|OTHER: Simulated visceral techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Family Centred Healthcare - Zero Separation and Couplet Care
Status: RECRUITING
Conditions: Premature Birth|Post Partum|Infant|Mother-Child Relations|Family
Interventions: BEHAVIORAL: Zero separation and couplet care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Efficacy of Mindfulness-based Stress Reduction in the Prevention of Perimenopausal Depression
Status: COMPLETED
Conditions: Perimenopausal Depression|Depressive Symptoms
Interventions: BEHAVIORAL: Mindfulness-based stress reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: YELLOW II Study: Reduction in Coronary Yellow Plaque, Lipids and Vascular Inflammation by Aggressive Lipid Lowering
Status: COMPLETED
Conditions: Obstructive Coronary Artery Disease|Coronary Artery Disease
Interventions: DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of an Osteoconductive Scaffold in ACL-Reconstruction
Status: ACTIVE_NOT_RECRUITING
Conditions: ACL - Anterior Cruciate Ligament Rupture|ACL|ACL Injury
Interventions: DEVICE: Osteoconductive scaffold-hamstring tendon composite repair|DEVICE: Hamstring tendon-only repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Evaluation of Fluoroquinolone Antibiotics Administered Intravenously in Intensive Care Patients With Normal Renal Function and With Renal Hyperfiltration
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: intravenous administration of levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: hydroxyurea|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride|DRUG: thioguanine|DRUG: tretinoin|DRUG: valspodar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Home-Based Exergaming Intervention
Status: WITHDRAWN
Conditions: Physical Activity|Health-related Fitness|Cognition|Screen Time
Interventions: BEHAVIORAL: Exergaming intervention group|BEHAVIORAL: Traditional physical activity comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Atherosclerotic Lesion|Lower Extremity Ischemia|Lower Extremity Claudication
Interventions: DEVICE: Percutaneous Implantation of the MAGNITUDE® Bioresorbable Arterial Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Mediated Immunity in Older Adults
Status: COMPLETED
Conditions: Immunity to Influenza Vaccine
Interventions: BIOLOGICAL: High dose influenza vaccine Sanofi-Pasteur|BIOLOGICAL: fluzone by sanofi pasteur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-Inflammatory Diet Effect in Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: OTHER: Antiinflammatory Diet|OTHER: Control Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Compare Two Anti-HIV Drug Combinations That Include Amprenavir in HIV-Infected Patients Who Have Failed Anti-HIV Drug Combinations That Did Not Include Amprenavir
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Abacavir sulfate|DRUG: Amprenavir|DRUG: Nelfinavir mesylate|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: 3D Printing of Positive Airway Pressure (PAP) Therapy Masks: a Single Site Pilot and Feasibility Study
Status: RECRUITING
Conditions: Sleep Disordered Breathing
Interventions: DEVICE: Customised PAP interfaces
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Virtual Reality Application on Pain, Anxiety and Comfort During Chest Tube Removal Procedure
Status: ENROLLING_BY_INVITATION
Conditions: Chest Tube Removal
Interventions: DEVICE: Group using virtual reality glasses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Correlation Between the SPhENo-Cardiograph™, a Seismocardiograph Device, and GE Vivid Q, an Echocardiograph, for Known Systemic Timing Intervals (STI)
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DEVICE: SPhENo-Cardiograph
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FX-322 in Sensorineural Hearing Loss
Status: COMPLETED
Conditions: Sensorineural Hearing Loss
Interventions: DRUG: FX-322|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PENG Block vs Supra-inguinal Fascia Iliaca Compartment Block for Postoperative Opioids Consumption and Early Motor Recovery After THA: a Randomized Controlled Non-inferiority Clinical Trial.
Status: UNKNOWN
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: Pericapsular nerves group (PENG) block|PROCEDURE: Supra-inguinal fascia-iliaca compartment block|DRUG: Ropivacaine 0,75% in PENG block|DRUG: Ropivacaine 0,375% in SFICB block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Qualia Mind on Cognition in a Healthy Population
Status: COMPLETED
Conditions: Healthy|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Qualia Mind|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical and MRI Evaluation of ACL Reconstruction Results in Adolescents With Follow-up at Least 3 Years.
Status: RECRUITING
Conditions: ACL Injuries|Knee Instability
Interventions: PROCEDURE: Anterior cruciate ligament reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extended Release Naltrexone for Opioid-Dependent Youth
Status: COMPLETED
Conditions: Drug Dependence
Interventions: DRUG: Extended Release Naltrexone|BEHAVIORAL: Psychosocial Treatment|DRUG: Buprenorphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 2 Different Doses of Pantoprazole on Gastric pH and Recurrent Bleeding in Patients Who Bled From Peptic Ulcers
Status: COMPLETED
Conditions: Peptic Ulcer Hemorrhage
Interventions: DRUG: pantoprazole infusion|DRUG: pantoprazole bolus|DRUG: no treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LACTIN-V Study for Recurrent Bacterial Vaginosis
Status: COMPLETED
Conditions: Bacterial Vaginosis
Interventions: BIOLOGICAL: Lactobacillus crispatus CTV-05|DRUG: Metronidazole|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The MAP Study: Fluocinolone Acetonide (FA)/Medidur (TM) for Age Related Macular Degeneration (AMD) Pilot
Status: COMPLETED
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Fluocinolone Acetonide/Medidur|DRUG: Fluocinolone Acetonide/Medidur
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating agenT-797 in Participants With Relapsed/Refractory Solid Tumors
Status: COMPLETED
Conditions: Tumor, Solid
Interventions: DRUG: agenT-797|DRUG: Approved ICIs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalency Study of Amlodipine Besylate Tablets, 10 mg of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Gemcitabine/Vinorelbine vs Sequential Gemcitabine Followed by Vinorelbine in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Gemcitabine plus Vinorelbine|DRUG: Sequential
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive and Blood Flow Effects of Mountain Tea
Status: COMPLETED
Conditions: Cognitive Change|Affect|Blood Pressure|Neuroimaging
Interventions: DIETARY_SUPPLEMENT: Sideritis Scardica|DIETARY_SUPPLEMENT: Ginkgo biloba|DIETARY_SUPPLEMENT: Placebo control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer|Metastatic Colorectal Cancer|Refractory Colorectal Carcinoma
Interventions: DRUG: Fruquintinib Combined With TAS-102
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis
Status: COMPLETED
Conditions: Sepsis Newborn
Interventions: OTHER: Control Group|DRUG: Treatment Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance Testing of Philips FAST SpO2 With Masimo Pulse Oximetry Sensors Across Skin Pigmentation
Status: RECRUITING
Conditions: Healthy
Interventions: DEVICE: Philips FAST SpO2 with Masimo Pulse Oximetry Sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Photodynamic Therapy (PDT) Effect on Large Surface Photodamaged Skin
Status: COMPLETED
Conditions: Actinic Keratosis|Photoaging|Solar Elastosis
Interventions: OTHER: Methylaminolevulinate - photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Ganoderma Spore Lipids Combined With Chemo in Patients With G.I. Cancers
Status: UNKNOWN
Conditions: Gastrointestinal Neoplasms
Interventions: DRUG: Ganoderma Spore Lipids|DRUG: Placebo|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With Interleukin-2 (IL-2) Plus Combination Anti-HIV-Drug Therapy (HAART) for Patients Formerly in ACTG 328
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine|DRUG: Didanosine|DRUG: Aldesleukin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT