pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Near-infrared Imaging Techniques for Identifying and Preserving Viable Parathyroid Glands During Thyroidectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypoparathyroidism Postprocedural
Interventions: PROCEDURE: Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Continuous Glucose Monitoring and Preterm Infants
Status: COMPLETED
Conditions: Infant, Very Low Birth Weight|Neonatal Hypoglycemia
Interventions: DEVICE: Unblinded - CGM|DEVICE: Blinded - CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Inspection of the Colon Using a Retrograde Viewing Device for Detection of Colorectal Polyps
Status: UNKNOWN
Conditions: Adenoma|Polyps
Interventions: DIAGNOSTIC_TEST: Retroviewing endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug Interaction Study To Investigate The Potential Effect Of Proton Pump Inhibitor On The Pharmacokinetics Of Palbociclib (PD-0332991)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Palbociclib alone|DRUG: Palbociclib + Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ONTAK in Patients With Relapsed or Refractory, B-Cell Non Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B-Cell
Interventions: DRUG: ONTAK (denileukin diftitox)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Melatonin vs Gabapentin for Post Trauma Surgery
Status: RECRUITING
Conditions: Anxiety, Preoperarative
Interventions: DRUG: Melatonin 6 MG|DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mite Asthma Pediatric Immunotherapy Trial
Status: COMPLETED
Conditions: Allergic Asthma Due to Dermatophagoides Farinae|Allergic Asthma Due to Dermatophagoides Pteronyssinus|Allergic Rhinitis Due to House Dust Mite
Interventions: BIOLOGICAL: HDM SLIT-tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Pharmacokinetic Study of the Fixed-dose Combination of Micronized Fenofibrate and Pitavastatin Ca
Status: COMPLETED
Conditions: Healthy Male Volunteers
Interventions: DRUG: Livasupril Cap.160/2mg|DRUG: Lipilfen cap. 160mg|DRUG: Livaro tab. 2mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines
Status: COMPLETED
Conditions: Norovirus Infections
Interventions: BIOLOGICAL: VXA-G1.1-NN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
Status: WITHDRAWN
Conditions: Hernia, Ventral|Hernia Incisional|Acute Kidney Injury|Restrictive Lung Disease|Intraabdominal Hypertension
Interventions: PROCEDURE: Abdominal reconstruction
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Cytokine Release Syndrome Prophylaxis and Treatment With Siltuximab Prior to Epcoritamab
Status: NOT_YET_RECRUITING
Conditions: Non-Hodgkin Lymphoma|Cytokine Release Syndrome
Interventions: DRUG: Siltuximab|DRUG: Epcoritamab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Risk in East London and Its Association With Vitamin D by Ethnic Group (DELVE)
Status: RECRUITING
Conditions: Hyperglycemia, Postprandial|Vitamin D Status
Interventions: OTHER: Glucose drink|OTHER: Pure orange juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Newton Study (NEW Dosing mainTenance Therapy Ovarian caNcer)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Primary Peritoneal Carcinoma
Interventions: DRUG: Niraparib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of IPACK Block (Interspace Between the Popliteal Artery and Capsule of Knee) With Spinal Anesthesia Versus Fentanyl Based Spinal Anesthesia for Knee Arthroscopic Meniscectomy
Status: COMPLETED
Conditions: Post Operative Pain
Interventions: PROCEDURE: spinal anesthesia using hyperbaric bupivacaine 0.5% (3ml) with fentanyl (25ug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation
Status: RECRUITING
Conditions: Atherosclerosis of Artery|Coronary Artery Disease|Peripheral Arterial Disease|Carotid Stenosis
Interventions: DRUG: Rivaroxaban 2.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Oral Doses of JTT-252
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: JTT-252 or Placebo|DRUG: JTT-252
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma|Sarcomatoid Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC v8|Stage IV Renal Cell Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Scan|PROCEDURE: Computed Tomography|BIOLOGICAL: Ipilimumab|PROCEDURE: Magnetic Resonance Imaging|DRUG: Myrciaria dubia Prebiotic Supplement|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Standardized Freeze-dried Grape Powder on High Density Lipoprotein (HDL) Function in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: OTHER: Freeze-dried Whole Grape Powder|OTHER: Grape Powder Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing the Safety and Bioactivity of SG1002 in Heart Failure Patients
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: sodium polysulthionate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metastatic Prostate Cancer Men's Attitudes Towards Treatment of the Local Tumour and Metastasis Evaluative Research
Status: COMPLETED
Conditions: Prostate Cancer Metastatic|Radiotherapy Side Effect|Surgery|Urologic Cancer|Quality of Life|Patient Satisfaction|Health Care Utilization
Interventions: OTHER: Semi-Structured Interview Healthcare Professional|OTHER: Semi-Structured Interview Patients|OTHER: Think Aloud Interview Patients|OTHER: Discrete Choice Experiment (DCE) Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma
Status: RECRUITING
Conditions: Colorectal Cancer|Cholangiocarcinoma
Interventions: DEVICE: Medtronic pump and Codman catheter|DRUG: Floxuridine (FUDR)|DRUG: Gemcitabine|DRUG: Oxaliplatin|DRUG: Irinotecan (CPT-11)|DRUG: Fluorouracil|DRUG: Anti-EGFR (Panitumumab or Cetuximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resolving Psychological Stress
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder|Alcohol Use Disorder
Interventions: DEVICE: RePS (Resolving Psychological Stress) - Threat ABM Training|DEVICE: RePS (Resolving Psychological Stress) - Neutral Attention Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare the Incidence of Squamous Cell Carcinoma (SCC) and Other Skin Neoplasia on Skin Areas Treated With Ingenol Disoxate Gel or Vehicle Gel for Actinic Keratosis on Face and Chest or Scalp
Status: TERMINATED
Conditions: Actinic Keratosis|Squamous Cell Carcinoma
Interventions: DRUG: ingenol disoxate gel 0.018%|DRUG: ingenol disoxate gel 0.037%|OTHER: Vehicle gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients
Status: TERMINATED
Conditions: Familial Adenomatous Polyposis (FAP)
Interventions: DRUG: Celecoxib|OTHER: Routine Medical Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Two Park-Based Activities on Emotional Well-Being in Adults With Mobility Impairments
Status: NOT_YET_RECRUITING
Conditions: Mobility Limitation|Physical Disability
Interventions: BEHAVIORAL: Physical Activity|BEHAVIORAL: Sensory Engagement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: D.T. PACE Versus High Dose Melphalan and Autologous Transplant in Patients With Previously Treated Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Precise Delivery of Remifentanil Decrease Coughing at Emergence From Anesthesia
Status: UNKNOWN
Conditions: Cough
Interventions: DRUG: Remifentanil|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation
Status: ACTIVE_NOT_RECRUITING
Conditions: Mitral Regurgitation|Valve Heart Disease|Heart Valve Diseases|Mitral Valve Disease|Mitral Disease
Interventions: DEVICE: SATURN TA System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dry Cupping Therapy Associated With the McKenzie Method in Patients With Chronic Low Back Pain
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Exercises and dry cupping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Forehead/Glabellar Rhytide Complex With Botulinum Toxin A Injection
Status: ACTIVE_NOT_RECRUITING
Conditions: Forehead Rhytid Complex|Glabellar Rhytid Complex
Interventions: PROCEDURE: Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Direct Oral Anticoagulants as a Prophylactic Anticoagulation of Catheter Induced Thrombosis
Status: NOT_YET_RECRUITING
Conditions: Anticoagulants; Increased
Interventions: DRUG: catheter induced thromboprophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Compare the Pharmacokinetics of a Dexamethasone Iontophoretic Patch to a Dexamethasone Injection
Status: UNKNOWN
Conditions: Lateral Epicondylitis (Tennis Elbow)
Interventions: DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Unexplained Subfertiliy
Status: UNKNOWN
Conditions: Unexplained Infertility
Interventions: OTHER: Acupuncture|OTHER: expectant management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Modified Thoracolumbar Interfascial Plane Block for Spinal Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Spine Disease
Interventions: DRUG: Bupivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Chemotherapy With Bevacizumab For Potentially Resectable Gastric Cancer With Liver Metastasis
Status: UNKNOWN
Conditions: Gastric Cancer|Liver Metastasis
Interventions: DRUG: Oxaliplatin;Capecitabine|DRUG: Oxaliplatin;Capecitabine;Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sulopenem Versus Ertapenem for Complicated Intra-abdominal Infection (cIAI)
Status: COMPLETED
Conditions: Intra Abdominal Infections
Interventions: DRUG: Ertapenem|DRUG: Sulopenem-Etzadroxil/Probenecid|DRUG: Ciprofloxacin|DRUG: Metronidazole|DRUG: Amoxicillin-Clavulanate|DRUG: Sulopenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bicruciate-retaining (2C) Total Knee Arthroplasty (TKA) Versus Posterior-stabilized (PS) Total Knee Arthroplasty (TKA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Total Knee Arthroplasty|Knee Osteoarthritis
Interventions: PROCEDURE: bicruciate-retaining total knee arthroplasty|PROCEDURE: posterior-stabilized total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy of High Intensity Laser Therapy and Low Level Laser Therapy in the Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome|Electromyography|Low-Level Laser Therapy|Ultrasound Imaging
Interventions: DEVICE: low level laser treatment|DEVICE: High intensity laser treatment|OTHER: wrist splint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Omega-3 Fatty Acid Supplementation and Tear Film Quality in Celiac Patients
Status: RECRUITING
Conditions: Dry Eye Syndromes|Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty ACids|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flaxseed Oil and Pomegranate Extract on Inflammation, Lipid Profile and Nutritional Status of Hemodialysis Patients
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Dialysis; Complications|Inflammation|Lipid Metabolism Disorders
Interventions: DIETARY_SUPPLEMENT: flaxseed oil and pomegranate dry extract|DIETARY_SUPPLEMENT: sunflower oil and microcrystalline cellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pharmacokinetic and Randomized Trial of Neoadjuvant Treatment With Anastrozole Plus AZD0530 in Postmenopausal Patients With Hormone Receptor Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Anastrozole|DRUG: AZD0530 (saracatinib)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pomalidomide, Dexamethasone, and Romidepsin for Rel/Ref Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Romidepsin|DRUG: pomalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Hematologic Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Waldenstrom Macroglobulinemia|Chronic Lymphocytic Leukemia|Hodgkin Disease|NonHodgkin Lymphoma|Mixed Lymphoproliferative Disease
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity
Status: COMPLETED
Conditions: Tooth Sensitivity
Interventions: DIAGNOSTIC_TEST: Herbal based mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Hegab Splint, Arthrocentesis, and Arthroscopy in Treatment of TMJ Closed Lock
Status: COMPLETED
Conditions: TMJ Disorder|TMJ Disc Disorder
Interventions: PROCEDURE: arthrocentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Zinc Oxide Versus Petrolatum Following Skin Surgery
Status: RECRUITING
Conditions: Surgical Incision|Surgery--Complications|Surgical Wound|Surgical Site Infection|Scar|Hypertrophic Scar
Interventions: DRUG: Topical zinc oxide vs. petrolatum post-surgical scars
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1380GCC: Prospective Study of GP-88 Blood Test in Healthy Women With Baseline Gail Model Risk Assessment Undergoing Screening for Breast Cancer
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: OTHER: Phlebotomy - Blood sampling for GP88 at MM|PROCEDURE: SOC Tissue biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heart-Brain Retraining for Stroke Rehabilitation
Status: COMPLETED
Conditions: Stroke
Interventions: BEHAVIORAL: Repetitive Task Practice (RTP)|BEHAVIORAL: Voluntary cycling + RTP|BEHAVIORAL: Assisted cycling + RTP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lopinavir/Ritonavir Monotherapy Versus Standard Highly Active Antiretroviral Therapy (HAART) in HIV/HCV Coinfected Antiretroviral (ARV) Naive Patients Starting Treatment With Anti-HCV Therapy
Status: UNKNOWN
Conditions: HIV Infections|Hepatitis C
Interventions: DRUG: LPV/r|DRUG: Nucleoside Reverse Transcriptase Inhibitors|DRUG: PEG-IFNa 2a|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vending Labeling Sales and Intercepts Study
Status: COMPLETED
Conditions: Food Preferences|Obesity|Weight Gain
Interventions: BEHAVIORAL: exposure to healthy labels only|BEHAVIORAL: exposure to healthiness information|BEHAVIORAL: exposure to physical activity equivalents|BEHAVIORAL: exposure to sweetened beverage tax messaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Capturing Outcomes of Clinical Activities Performed by a Rounding Pharmacist Practising in a Team Environment
Status: COMPLETED
Conditions: Heart Failure, Congestive|Pulmonary Disease, Chronic Obstructive|Pneumonia|Diabetes Mellitus, Type 2|Coronary Arteriosclerosis
Interventions: BEHAVIORAL: Integration of a team based clinical pharmacist|DRUG: Optimizing therapeutic treatments|BEHAVIORAL: Optimizing processes of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain
Status: RECRUITING
Conditions: Endometriosis
Interventions: DRUG: Elagolix|DRUG: Placebo|DRUG: Combined Oral Contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Rotator Cuff Training on Hand Grip in Adults
Status: NOT_YET_RECRUITING
Conditions: Hand Grasp
Interventions: OTHER: open chain exercises for rotator cuff muscles|OTHER: Advices for postural correction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of Minimally Invasive Glaucoma Surgery on Primary Angle Closure Glaucoma
Status: UNKNOWN
Conditions: Glaucoma, Angle-Closure
Interventions: PROCEDURE: ab interno trabeculectomy with Trabectome|PROCEDURE: trabeculectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Elderly NSCLC/D vs DP (JCOG0207)
Status: TERMINATED
Conditions: Non-small-cell Lung Cancer
Interventions: DRUG: Weekly docetaxel alone|DRUG: Weekly docetaxel + cisplatin combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bright Light on Mood and Sleep in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Depression
Interventions: DEVICE: light therapy 30 min morning and evening, three months|DEVICE: light therapy 30 min morning and evening, three months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2a Extension Study of Ataluren (PTC124) in Duchenne Muscular Dystrophy (DMD)
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Ataluren
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial: Effect of an Exercise Routine on Postoperative Shoulder Pain in Laparoscopic Hysterectomy
Status: RECRUITING
Conditions: Postoperative Pain|Laparoscopic Hysterectomy for Benign Conditions
Interventions: OTHER: Shoulder exercises|OTHER: Hand exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Multi-omics Technique to Predict the Efficacy of Chemoradiotherapy Combined With Immunotherapy for r/m NPC
Status: NOT_YET_RECRUITING
Conditions: Multi-omics Technique|Nasopharyngeal Carcinoma|Recurrent and Metastatic Nasopharyngeal Carcinoma|Efficacy of Chemoradiotherapy and Immunotherapy
Interventions: DRUG: cisplatin-based chemoradiotherapy combined with immunotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Stage II|Colorectal Cancer Stage III
Interventions: DRUG: Metronidazole Oral Tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Center, Open-label, Randomized, Pilot Study to Evaluate the Safety and Efficacy of a Tacrolimus Modified Release, ADVAGRAF®, Versus Tacrolimus Twice Daily, PROGRAF® in Stable Renal Recipients
Status: COMPLETED
Conditions: Renal Transplantation|Kidney Transplantation|Stable Renal Recipients
Interventions: DRUG: ADVAGRAF|DRUG: PROGRAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a 24/7 Palliative Care Service Integration in a Metropolitan Area on Non-oncologic Patients
Status: COMPLETED
Conditions: Palliative Medicine|Hospice and Palliative Care Nursing|Palliative Care
Interventions: OTHER: 24/7 Telephonic Palliative Care Service availability
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Status: UNKNOWN
Conditions: Anesthesia, Local
Interventions: DRUG: Bupivacaine|OTHER: SALINE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Appropriateness of the Voriconazole Dosing Regimen
Status: COMPLETED
Conditions: Fungal Infection
Interventions: DRUG: Voriconazole Oral Product (Vfend®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topical Corticosteroid Use in Addition to Oral Antivirals for Prevention of Recurrence of Herpes Simplex Virus (HSV) Keratitis
Status: WITHDRAWN
Conditions: Herpes Simplex Virus Keratitis
Interventions: DRUG: oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily|DRUG: oral acyclovir 400 mg BID OR valacyclovir 500 mg qdaily + topical corticosteroid eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Radiotherapy for Metastatic Kidney Cancer Being Treated With Sunitinib
Status: COMPLETED
Conditions: Clear Cell Metastatic Renal Cell Carcinoma
Interventions: RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Efficacy of Levodopa-carbidopa Intestinal Gel (LCIG) for the Treatment of Non-motor Symptoms in Patients With Advanced Parkinson's Disease
Status: COMPLETED
Conditions: Advanced Parkinson's Disease
Interventions: DRUG: Levodopa-Carbidopa Intestinal Gel|PROCEDURE: Percutaneous Endoscopic Gastrostomy with Jejunal Extension (PEG-J)|DRUG: Levodopa-carbidopa Immediate Release (LC-IR) Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Aerobic Versus Resistance Training in Post Percutaneous Coronary Intervention Obese Patients
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Aerobic Training|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Diclofenac Potassium for Oral Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Endothelial Progenitor Cells (EPCs) From Peripheral Blood in the Treatment of Critical Limb Ischemia
Status: COMPLETED
Conditions: Critical Limb Ischemia
Interventions: OTHER: Endothelial progenitor cells intramuscular implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pueraria Lobata and Pueraria Thomsonii for Mild Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: Pueraria lobata|DRUG: Pueraria thomsoni|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training in Youth With Inflammatory Bowel Disease
Status: COMPLETED
Conditions: Pediatric Inflammatory Bowel Diseases|Pediatric Crohns Disease|Pediatric Ulcerative Colitis
Interventions: OTHER: Exercise training program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of Mobile Applications in Obese and Overweight Adolescents for Health Improvement
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight Adolescents|Obesity, Adolescent|Physical Inactivity|Mobile Phone Use|Behavior, Health
Interventions: BEHAVIORAL: STRAVA mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A HIV Study Of A Fixed-Dose Combination Tablet In Antiretroviral Experienced Patients
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I|HIV Infection
Interventions: DRUG: abacavir/lamivudine|DRUG: abacavir|DRUG: lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing the BAGUERA C to the Marketed Mobi-C® for the Treatment of Single Level Cervical Disc Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Cervical Disc Disease
Interventions: DEVICE: BAGUERA®C Cervical Disc Prosthesis|DEVICE: Mobi-C® Cervical Disc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Palonosetron Intravenous in Prevention of Chemotherapy Induced Nausea and Vomiting in Pediatric Patients
Status: COMPLETED
Conditions: Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Palonosetron|DRUG: Palonosetron|DRUG: Ondansetron|DRUG: Placebo to Ondansetron|DRUG: Placebo to Ondansetron|DRUG: Placebo to Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Elemental Formula Hypoallergenicity
Status: COMPLETED
Conditions: Food Hypersensitivity
Interventions: OTHER: Amino Acid formula|OTHER: Commercially available Amino Acid Formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Advancing Postmenopausal Preventive Therapy
Status: RECRUITING
Conditions: Atherosclerosis|Cognitive Decline
Interventions: COMBINATION_PRODUCT: Oral bazedoxifene 20 mg / conjugated estrogens 0.45 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function
Status: COMPLETED
Conditions: Fabry Disease
Interventions: BIOLOGICAL: PRX-102 (pegunigalsidase alfa)|BIOLOGICAL: agalsidase beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Helping HAND: Healing Anorexia Nervosa Digitally
Status: ACTIVE_NOT_RECRUITING
Conditions: Anorexia Nervosa
Interventions: DEVICE: SilverCloud Health Mobile Intervention|DEVICE: Social Networking Intervention: Facebook
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Particle Deposition and Acute Effects of Symbicort® Forte Turbohaler®) in COPD Patients.
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Symbicort® forte Turbohaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Pharmacokinetic Profiles and Safety of CKD-383.
Status: COMPLETED
Conditions: Type2 Diabetes Mellitus
Interventions: DRUG: CKD-501, D745, D150|DRUG: CKD-383
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VTD Followed By MPT Maintenance As a First Line Treatment For The Patients With MM Who Are Non-Transplant Candidates
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal High Flow Therapy in Surgical Patients With Unrecognized Obstructive Sleep Apnea
Status: SUSPENDED
Conditions: Obstructive Sleep Apnea|Sleep Disordered Breathing
Interventions: OTHER: Nasal High Flow|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Magnevist® Injection Enhanced MRA at Two Dose Levels Compared to Non Contrast MRA for the Detection of Structural Abnormalities of the Infrarenal Aorta and Peripheral Arteries
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DRUG: Gadopentetate dimeglumine (Magnevist, BAY86-4882)|DRUG: Gadopentetate dimeglumine (Magnevist, BAY86-4882)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neuromuscular Blockade on Shoulder Pain of Elderly
Status: COMPLETED
Conditions: Malignant Neoplasms of Digestive Organs|Malignant Neoplasms of Female Genital Organs|Malignant Neoplasms of Male Genital Organs|Malignant Neoplasms of Urinary Tract
Interventions: DRUG: Deep Neuromuscular Blockade (NMB)|DRUG: Moderate Neuromuscular Blockade (NMB)|DRUG: Sugammadex|DRUG: Neostigmine|BEHAVIORAL: Pain Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Comparing 2% Chlorhexidine in 70% Isopropyl Alcohol Versus 2% Aqueous Chlorhexidine
Status: UNKNOWN
Conditions: Anti-infecting Agents, Local
Interventions: DRUG: 2% aqueous chlorhexidine|DRUG: 2% Chlorhexidine 70% isopropyl alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Response Relationship of Ginger Flour Footbaths in Healthy Volunteers
Status: COMPLETED
Conditions: Thermogenesis by Different-dosage Ginger Flour Footbaths
Interventions: OTHER: 3-g footbath|OTHER: 6-g footbath|OTHER: 12-g footbath|OTHER: Warm water footbath
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Brimonidine
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DRUG: Brimonidine|DRUG: Tropicamide|DRUG: Phenylephrine Ophthalmic Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study Using Biologics to Improve Multi OIT Outcomes (COMBINE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypersensitivity|Food Allergy|Hypersensitivity, Food|Peanut Hypersensitivity|Peanut Allergy
Interventions: DRUG: Omalizumab|DRUG: Dupilumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A PhaseⅠ/Ⅱ Study of Simmitinib or Irinotecan Liposomes Combined With DP303c in Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Localized Advanced or Metastatic Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma|Expressing Human Epidermal Growth Factor Receptor-2 (HER-2)|Disease Progression After Receiving at Least One and at Most Two Lines of Systemic Treatment in the Past
Interventions: DRUG: DP303c|DRUG: Simmitinib tablets|DRUG: Irinotecan liposomes|DRUG: Paclitaxel or docetaxel or irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Absence of Liner Following the Selective Caries Removal (ALFSCaRe)
Status: WITHDRAWN
Conditions: Caries; Dentin|Dental Restoration Failure of Marginal Integrity
Interventions: PROCEDURE: Restoration of carious lesions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Effectiveness and Safety Study Evaluating OROS Methylphenidate Hydrochloride (HCl), Ritalin (Methylphenidate HCl) and Placebo in Children With Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Placebo|DRUG: OROS (methylphenidate HCl)|DRUG: Ritalin (methylphenidate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-factor Model Constraction for Early Warning and Diagnosis of MDD
Status: UNKNOWN
Conditions: Major Depressive Disorder|Bipolar Disorder|Omega-3 Fatty Acids
Interventions: DRUG: Omega 3 fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems
Status: RECRUITING
Conditions: Rectal Adenocarcinoma
Interventions: DEVICE: MRI-guided radiotherapy by on-board DWI sequences
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase IV Clinical Study to Compare the Efficacy of the Ophthalmic Solution Humylub Ofteno® PF With Hyabak® and Lagricel Ofteno® PF as Treatment for Dry Eye.
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Sodium hyaluronate 0.1%/chondroitin sulfate 0.18%|DRUG: Sodium hyaluronate 0.15%|DRUG: Sodium hyaluronate 0.4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Post-tetanic Count on Subsequent Train-of-four During Recovery From Rocuronium
Status: COMPLETED
Conditions: Post-tetanic Count on One Arm, the Other Arm is the Control
Interventions: DEVICE: NMT (a device that can do neurostimulation and can record the response on the stimulation by Datex)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)
Status: WITHDRAWN
Conditions: Hepatic Encephalopathy|HE|Cirrhosis|Altered Mental Status|AMS
Interventions: DRUG: Lactulose|DRUG: Polyethylene Glycol 3350
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chest Physiotherapy Technique Increasing Inspiratory Flow on Weaning From Non Invasive Ventilation
Status: COMPLETED
Conditions: Neonatal Respiratory Distress Syndrome|Intubation, Intratracheal
Interventions: PROCEDURE: Chest physiotherapy|PROCEDURE: Usual surveillance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hand Therapy Intervention Versus Traditional Occupational Therapy to Prevent Chemotherapy Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Adenocarcinoma of Pancreas
Interventions: OTHER: Hand Therapy Until CIPN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: FOLFIRI Alternate With FOLFOX in Untreated Metastatic Gastric and Esophageal Adenocarcinoma
Status: TERMINATED
Conditions: Metastatic Gastro-esophageal Adenocarcinoma
Interventions: DRUG: FOLFOX and FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin Combined With S-1(SOX) Neoadjuvant Chemotherapy for Different Cycles in Patients With Gastric Cancer
Status: RECRUITING
Conditions: Gastric Cancer|Chemotherapy Effect
Interventions: DRUG: Chemotherapy drug|PROCEDURE: Gastrectomy|PROCEDURE: Laparoscopic exploration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Rich in Growth Factors (PRGF-Endoret)in the Treatment of Androgenetic Alopecia
Status: UNKNOWN
Conditions: Androgenetic Alopecia
Interventions: DEVICE: PRGF-Endoret|OTHER: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Nasonex® Compared With Placebo for the Relief of Symptoms Associated With Acute Bacterial Sinusitis When Used With Antibiotics (Study P04824AM3)
Status: TERMINATED
Conditions: Sinusitis
Interventions: DRUG: MFNS and antibiotic|DRUG: Matching Placebo nasal spray plus antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HypErthermia as an Additional Treatment for the Biology and Experience of Depression: Study 2
Status: ACTIVE_NOT_RECRUITING
Conditions: Major Depressive Disorder|Depression
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|DEVICE: Active Whole-Body Hyperthermia (Active WBH)|DEVICE: Sham Whole-Body Hyperthermia (Sham WBH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detecting an Early Response to Donepezil With Measures of Visual Attention
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donepezil Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Relationship Between Prenatal Maternal Distress and the Quality of General Movements at 3 Months
Status: COMPLETED
Conditions: Cerebral Palsy|Infant Development|Maternal Distress
Interventions: OTHER: Assessment of the quality of Genaral Movements (GMs)|OTHER: State-Trait Anxiety Inventory-Trait, (STAI-T)|OTHER: Beck Depression Inventory, (BDI)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Application of THRIVE in Burn Children With Suspected Difficult Airway
Status: NOT_YET_RECRUITING
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Fruquintinib With PD-1 Inhibitors Versus TAS-102 With Bevacizumab in Late-Line mCRC
Status: COMPLETED
Conditions: Metastatic Colorectal Adenocarcinoma
Interventions: DRUG: Fruquintinib|DRUG: PD-1 inhibitors|DRUG: Trifluridine/Tipiracil|DRUG: Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intermittent Hypoxia-hyperoxia Conditioning as a New Therapeutic Intervention to Reduce Hypertension (HyperIHHC)
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: OTHER: Intermittent hypoxia-hyperoxia conditioning|OTHER: Placebo intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 in Combination With BP102 and XELOX in Patient With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: SHR-1210|DRUG: BP102|DRUG: oxaliplatin|DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: PF-04965842|DRUG: PF04965842
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Imaging Study of the Changes in [18F]F-AraG Uptake Following Anti-PD-1 Therapy in Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Advanced Stage Non-small Cell Lung Cancer
Interventions: DIAGNOSTIC_TEST: [18F]F-AraG PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Vibration During Constraint-induced Movement Therapy
Status: NOT_YET_RECRUITING
Conditions: Hemiparesis
Interventions: DEVICE: Vibration|BEHAVIORAL: constraint-induced movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER