pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Virtual Reality and Olfactory Stimuli Multimodal Intervention to Reduce Post-Operative Pain and Anxiety in Patients Undergoing Cardiothoracic Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Anxiety Postoperative|Opioid Use
Interventions: DEVICE: Virtual Realty using a Microsoft Hololens, Empatica HR wristband, and EEG|DEVICE: Essence Olfactory Necklace|DEVICE: Bedside Olfaction Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Lenalidomide(Revlimid) Plus Rituximab (Revlirit Regimen) in Elderly Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Status: TERMINATED
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: Lenalidomide plus Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tai Chi Exercise on Mechanical Joint Loading in Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Optimized Tai Chi intervention|BEHAVIORAL: Traditional Tai Chi intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation
Status: COMPLETED
Conditions: Mydriasis
Interventions: DRUG: Tropicamide 1%-Phenylephrine 2.5% ophthalmic solution (TR/PE)|DRUG: Tropicamide 1% ophthalmic solution (TR)|DRUG: Phenylephrine 2.5% ophthalmic solution (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout
Status: COMPLETED
Conditions: Gout
Interventions: BIOLOGICAL: Pegloticase|DRUG: methotrexate|DRUG: placebo|DIETARY_SUPPLEMENT: folic acid|DRUG: gout flare prophylaxis regimen|DRUG: fexofenadine|DRUG: acetaminophen|DRUG: methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Interventions on Serum and Macrophage Atherogenicity
Status: UNKNOWN
Conditions: Dietary Habits|Serum; Disease|Macrophage Atherogenicity|Atherosclerosis
Interventions: DIETARY_SUPPLEMENT: monosaccharides|DIETARY_SUPPLEMENT: Disaccharides|DIETARY_SUPPLEMENT: Amino acids|DIETARY_SUPPLEMENT: Artificial Sweeteners|OTHER: Control- water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse
Status: RECRUITING
Conditions: Uterine Prolapse
Interventions: PROCEDURE: Minimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP)|PROCEDURE: Vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mapracorat Ophthalmic Formulation in Subjects With Allergic Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: Mapracorat|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: OCT Angiography Software Evaluation Study
Status: COMPLETED
Conditions: Retina Condition Followed by Fluorescein Angiography Imaging
Interventions: DEVICE: Maestro2 OCTA|DEVICE: Cirrus HD-OCT 5000|DEVICE: TRC-50DX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ACD440 Gel in Peripheral Neuropathic Pain
Status: COMPLETED
Conditions: Peripheral Neuropathic Pain
Interventions: DRUG: ACD440 Gel 14mg/g|DRUG: Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Menthol Gum Chewıng on Postoperatıve Nausea, Vomiting, and Length Of Hospital Stay in Children Undergoing Appendectomy: A Randomızed Controlled Trıal
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting|Hospitalism in Children
Interventions: OTHER: intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heterologous SARS-CoV-2 Vaccination With ChAdOx-1 and BNT162b2
Status: UNKNOWN
Conditions: SARS-CoV2 Infection
Interventions: BIOLOGICAL: Vaxzevria|BIOLOGICAL: Comirnaty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: On-site Cytopathology EUS-FNA
Status: COMPLETED
Conditions: Pancreatic Neoplasms|Pancreatic Cancer
Interventions: PROCEDURE: EUS-guided FNA performed with on-site Cytopathologist|PROCEDURE: EUS-guided FNA performed without on-site Cytopathologist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Gamma-Knife Radiosurgery Using Magnetic Resonance Imaging (MRI) Spectroscopy for Recurrent Glioma
Status: TERMINATED
Conditions: Glioblastoma
Interventions: PROCEDURE: Gamma Knife Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous and Epidural Spinal Stimulation for Enabling Motor Function in Humans With Motor Complete Paraplegia
Status: TERMINATED
Conditions: Paraplegia, Spinal|Paraplegia, Complete|Paraplegia; Traumatic
Interventions: DEVICE: Transcutaneous spinal cord stimulator|DEVICE: Epidural spinal cord stimulation system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effectiveness of Zonisamide in Alcohol Dependent Veterans
Status: TERMINATED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Zonisamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of a Nutraceutical Supplement With Standardized Botanicals in Peri-menopausal and Menopausal Women With Thinning Hair
Status: UNKNOWN
Conditions: Hair Thinning
Interventions: DIETARY_SUPPLEMENT: Nutrafol Supplement Capsules|OTHER: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ertugliflozin for Functional Mitral Regurgitation
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Left Ventricular Systolic Dysfunction
Interventions: DRUG: Ertugliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3437943 in Chinese Participants With Obesity Or Overweight
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: DRUG: LY3437943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brief Interventions for Short-Term Suicide Risk Reduction in Military Populations
Status: COMPLETED
Conditions: Suicide|Suicidal Ideation
Interventions: BEHAVIORAL: Treatment As Usual (TAU)|BEHAVIORAL: Standard Crisis Response Plan (S-CRP)|BEHAVIORAL: Enhanced Crisis Response Plan (E-CRP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures
Status: COMPLETED
Conditions: Epilepsy, Partial, Motor|Epilepsy, Complex Partial|Epilepsy, Simple Partial|Focal Motor Epilepsy
Interventions: DRUG: placebo|DRUG: carisbamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotics For Rehabilitation Therapy: Functional Versus Individual Joint Training
Status: COMPLETED
Conditions: Cerebrovascular Accident
Interventions: DEVICE: Functional/ Multi-joints activities|DEVICE: Individual Joint Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating a Standardized Checklist Bundle for Optimizing Procedural Ergonomics in Endoscopy
Status: NOT_YET_RECRUITING
Conditions: Injuries
Interventions: BEHAVIORAL: Standardized Checklist for Optimizing Procedural Ergonomics in Endoscopy (SCOPE- E) Bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: empagliflozin|DRUG: metformin (Glucophage®)|DRUG: metformin (Glucophage®)|DRUG: empagliflozin|DRUG: empagliflozin and metformin|DRUG: empagliflozin and metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy and Safety of 2 Dose Regimens of Subcutaneous Administration of TEV-48125 Versus Placebo for the Preventive Treatment of Chronic Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Fremanezumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Intestinal Barrier Function and Inflammation Via Butyrate-promoting Dietary Fibre
Status: UNKNOWN
Conditions: Microscopic Colitis
Interventions: DIETARY_SUPPLEMENT: Dietary fibre|DIETARY_SUPPLEMENT: Placebo compound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antiviral Prophylaxis and Infant Vaccination to Prevent Perinatal Hepatitis B Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis B|Pregnancy
Interventions: DRUG: Anti-HBV antiviral prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pneumatic Retinopexy Versus Vitrectomy for Retinal Detachment in Patients With Extended Criteria
Status: UNKNOWN
Conditions: Rhegmatogenous Retinal Detachment
Interventions: PROCEDURE: Pneumatic retinopexy|PROCEDURE: Vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Interferon gamma-1b|BIOLOGICAL: Donor Leukocyte Infusion (DLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Clopidogrel on Incidence of Silent Brain Infarction
Status: RECRUITING
Conditions: Silent Brain Infarction
Interventions: DRUG: Clopidogrel treatment|DRUG: Aspirin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF
Status: COMPLETED
Conditions: Age-related Macular Degeneration|Diabetic Macular Edema|Retinal Vein Occlusion
Interventions: BIOLOGICAL: Blood Sample Collection|DRUG: Aflibercept|DRUG: Bevacizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Nicotine|DRUG: Nicotine|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: FPI-2265 (225Ac-PSMA-I&T) for Patients With PSMA-Positive Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Status: RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: FPI-2265
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Intracranial Lesions on Bispectral Index
Status: COMPLETED
Conditions: Supratentorial Brain Tumor
Interventions: DEVICE: BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations|DEVICE: BIS values at return of consciousness in patients + predicted and measured propofol plasma concentrations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping: A Cross Sectional Observational Study
Status: UNKNOWN
Conditions: Three-Dimensional Ultrasonography Versus Magnetic Resonance Imaging for Fibroid Mapping
Interventions: RADIATION: three-Dimensional ultrasonography|RADIATION: Magnetic resonance imaging|PROCEDURE: myomectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CF Bronchodilation
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Diseases|Cystic Fibrosis
Interventions: DRUG: Salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Faricimab|OTHER: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rucaparib in Combination With Other Anticancer Agents in Participants With a Solid Tumor (SEASTAR)
Status: TERMINATED
Conditions: Ovarian Cancer|Triple-negative Breast Cancer|Urothelial Carcinoma|Solid Tumor
Interventions: DRUG: Rucaparib|DRUG: Lucitanib|DRUG: Sacituzumab govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Analgesic Efficiency Between IPACK Block and Surgical Infiltration After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: OTHER: Injection of local anesthetics during total knee arthroplasty by a locoregional anesthesia named IPACK block|OTHER: Injection of local anesthetics during total knee arthroplasty by surgical infiltration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IR and Microvascular Blood Flow in SCI
Status: COMPLETED
Conditions: Spinal Cord Injury|Insulin Resistance
Interventions: DRUG: Insulin iontophoresis|DRUG: Placebo Iontophoresis|DRUG: Acetylcholine Iontophoresis|OTHER: Heat application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose Range Finding Study of Bimagrumab in Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DRUG: bimagrumab|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone and Postoperative Bleeding Following Tonsillectomy in Children
Status: TERMINATED
Conditions: Pain, Postoperative|Tonsillar Bleeding|Postoperative Nausea and Vomiting
Interventions: DRUG: Dexamethasone|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Lesinurad and Allopurinol Combination Extension Study in Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: Lesinurad|DRUG: Lesinurad
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of D-Fagomine on Glycaemic Response to Sucrose in Men
Status: COMPLETED
Conditions: Glycaemic Response|Insulinemic Response
Interventions: OTHER: D-Fagomine|OTHER: D-Fagomine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of the Operative Day on the Average Duration of Stay in Primary Hip and Knee Replacements
Status: COMPLETED
Conditions: Length of Stay|Arthroplasty
Interventions: OTHER: Determine the DMS of the Total Hip Prosthesis of the University Hospital of Amiens (PTH) and the Total Knee Prosthesis (PTG)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Culturally Adapted Group Cognitive Behavior Therapy (CaGCBT-SUDs) for Substance Use Disorders and Their Caregivers
Status: RECRUITING
Conditions: Treatment|Waitlist
Interventions: BEHAVIORAL: Cultural Adapted Group cognitive Behaviroal therapy (CaGCBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Midazolam & Ketamine Versus Midazolam & Fentanyl for Sedation in Ambulatory Colonoscopies
Status: COMPLETED
Conditions: Colonoscopy|Conscious Sedation
Interventions: DRUG: Midazolam, Fentanyl|DRUG: KETAMINE, MIDAZOLAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lavender Oil Aromatherapy for The Treatment of Acute Anxiety During Bone Marrow Biopsy Procedures
Status: WITHDRAWN
Conditions: Hematologic Diseases
Interventions: OTHER: Lavender Oil Aromatherapy|OTHER: Placebo oil|PROCEDURE: BMAB procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Emtricitabine|DRUG: Enfuvirtide|DRUG: Ritonavir|DRUG: Saquinavir|DRUG: Tenofovir disoproxil fumarate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avoid and Resist Strategies for Weight Management
Status: RECRUITING
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Home food environment and grocery delivery (AVOID)|BEHAVIORAL: Inhibitory control training (RESIST)|BEHAVIORAL: WW
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Smart Technology Facilitated Patient-centered Venous Thromboembolism Management
Status: NOT_YET_RECRUITING
Conditions: Venous Thromboembolism|Digital Health|Health Education
Interventions: OTHER: mobile venous thromboembolism application (mVTEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 3-year Study of Menostar Versus Evista to Prevent Osteoporosis in Post-menopausal Women
Status: COMPLETED
Conditions: Osteopenia
Interventions: DRUG: Menostar (Estradiol, BAY86-5435)|DRUG: Raloxifene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Child and Family Outcomes and Consumer Satisfaction for Online vs Staff-Delivered Parenting Intervention
Status: COMPLETED
Conditions: Childhood Disruptive Behavior Disorders|Oppositional Defiant Disorder|Conduct Disorder|Attention Deficit Hyperactivity Disorder|Parent-Child Interactions
Interventions: BEHAVIORAL: Triple P--Positive Parenting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC
Status: RECRUITING
Conditions: Non-Small-Cell Lung Cancer
Interventions: BIOLOGICAL: CAB-AXL-ADC|BIOLOGICAL: PD-1 inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of a Known and Marketed Product, Itraconazole (Mycosis Treatment) on Lu AF11167 Entering the Body and Subsequently Elimination. The Study is a Drug-drug Interaction Study in Healthy Volunteers.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lu AF11167|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans
Status: ACTIVE_NOT_RECRUITING
Conditions: Moral Injury
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy for Moral Injury (ACT-MI)|BEHAVIORAL: Present Centered Therapy (PCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Analgesia After Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Total Knee Arthroplasty
Interventions: DRUG: naropin|DRUG: marcaine|DRUG: sufentanil|DRUG: neurontin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation
Status: TERMINATED
Conditions: Chronic Constipation
Interventions: DEVICE: taVNS|DRUG: Laxative Agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Energy- and Protein-rich Foods on Physiological Functions and Quality of Life in Undernourished Patients
Status: UNKNOWN
Conditions: Malnutrition
Interventions: OTHER: Individualised nutritional therapy|OTHER: Usual nutrition care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Gingival Recession Using Gingival Composite Restoration Versus Coronally Advanced Flap
Status: UNKNOWN
Conditions: Gingival Recession
Interventions: PROCEDURE: coronally advanced flap|PROCEDURE: restorative intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of the Synbiotic Probinul-Neutro® on Gastrointestinal Symptoms and Plasma p-Cresol Level in Chronic Renal Failure
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: SYNBIOTIC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement
Status: RECRUITING
Conditions: Erectile Dysfunction|Penile Prosthesis; Complications, Infection or Inflammation
Interventions: DRUG: Chlorhexidine|DRUG: Gentamicin|DRUG: Rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Breast Cancer|Locally Advanced Breast Cancer|Advanced Breast Cancer|BRCA2 Mutation|BRCA1 Mutation
Interventions: DRUG: Palbociclib|DRUG: Olaparib|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)
Status: RECRUITING
Conditions: Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Acute Lymphocytic Leukemia
Interventions: GENETIC: Dose Escalation Phase:CD19.CAR/28 and CD19.CAR/28137 T cells|GENETIC: Expansion Phase: CD19.CAR/28 and CD19.CAR/28137 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Conventional Physical Therapy in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Dry Needling, Conventional PT|OTHER: Conventional PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac MRI-guided Deferiprone Therapy for Acute Myocardial Infarction Patients
Status: RECRUITING
Conditions: Acute Myocardial Infarction Type 1
Interventions: DRUG: Deferiprone Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PN20 for the Prevention of Chemotherapy-induced Thrombocytopenia in Lymphoma or Solid Tumor Patients
Status: RECRUITING
Conditions: Thrombocytopenia
Interventions: DRUG: PN20
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: First Line Obstructive Sleep Apnea Treatment Study
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Mandibular advancement device (MAD)|DEVICE: Continuous positive airway pressure (CPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vaginal and Laparoscopic Apical Fixation Techniques for Pelvic Organ Prolapse Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Vaginal|PROCEDURE: Laparoscopic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Cardiac Prehabilitation, REhabilitation and Patient EDucation on Outcomes in Patients Undergoing First-time AF Ablation
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Exercise Intervention|BEHAVIORAL: Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of the Safety, Pharmacokinetics, and Antitumor Activity of AK105 in Subjects With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancer
Interventions: BIOLOGICAL: AK-105
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence in Ghana
Status: COMPLETED
Conditions: Malaria Asymptomatic Parasitaemia
Interventions: OTHER: Mass testing using RDTs|DRUG: Treatment for all cases confirmed positive malaria cases with ACTs|OTHER: Determination of Hb|OTHER: Household survey|OTHER: Community-base management of malaria
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate the Safety and Tolerability of Tirbanibulin Ointment 1% in Adult Participants With Actinic Keratosis
Status: COMPLETED
Conditions: Keratosis, Actinic
Interventions: DRUG: Tirbanibulin ointment 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Interval Training in Prediabetes
Status: UNKNOWN
Conditions: Prediabetic State
Interventions: BEHAVIORAL: High intensity interval training (HIIT)|BEHAVIORAL: Moderate intensity continuous training (MICT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Leptin in the Neuroendocrine and Immune Response to Fasting
Status: COMPLETED
Conditions: Fasting
Interventions: DRUG: r-metHuLeptin|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Essential Acute Stroke Care in Low Resource Settings: a Pilot studY
Status: NOT_YET_RECRUITING
Conditions: Acute Stroke
Interventions: OTHER: Acute stroke care Intervention arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Web-based Muscle-strengthening and Aerobic Physical Activity Intervention for Latinas
Status: COMPLETED
Conditions: Inactivity, Physical
Interventions: BEHAVIORAL: Aerobic plus muscle-strengthening physical activity intervention|BEHAVIORAL: Original physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Trial of Endocrine Against Locoregional Therapy First in Postmenopausal Women With Early Breast Cancer
Status: TERMINATED
Conditions: Operable Breast Neoplasms
Interventions: DRUG: letrozole (Femara)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Status: COMPLETED
Conditions: Rhabdomyosarcoma|Osteosarcoma|Ewing Sarcoma|Soft Tissue Sarcoma|Neuroblastoma|Wilms Tumor|Malignant Peripheral Nerve Sheath Tumor|Clival Chordoma|Non-CNS Solid Tumors
Interventions: BIOLOGICAL: HSV1716
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of FB2001 in Healthy Subjects and Patients With COVID-19 Infection
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: FB2001|DRUG: FB2001 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Traditional Chinese Medicine on Bronchiectasis Patients
Status: UNKNOWN
Conditions: Bronchiectasis
Interventions: DRUG: Bufei Huatan granule|DRUG: Yifei Qinghua granule|DRUG: Placebo Bufei Huatan granule|DRUG: Placebo Yifei Qinghua granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed +/- Carboplatin as Second Line Treatment in NSCLC
Status: UNKNOWN
Conditions: Advanced Non-Small Cell Lung Cancer
Interventions: DRUG: Pemetrexed|DRUG: Pemetrexed plus carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation
Status: COMPLETED
Conditions: Osteopenia|Osteoporosis
Interventions: DRUG: Pamidronate|DRUG: Calcium and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lumbar Brace Deployment in the Emergency Department for Benign Low Back Pain
Status: SUSPENDED
Conditions: Low Back Pain|Brace|Emergencies|Pain|Health Care Resources
Interventions: DEVICE: Horizon 627 Lumbar Brace, Aspen Medical Company, Oak Canyon, Irvine, CA 92618
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Study to Compare the Cordis SMART™ Stent System With the Bard® Luminexx™ Stent
Status: COMPLETED
Conditions: Arterial Occlusive Diseases
Interventions: DEVICE: Smart Stent|DEVICE: Luminexx Stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-frequency Rotating Magnetic System Combined With Systemic Anti-tumor Therapy for Advanced Lung Cancer
Status: UNKNOWN
Conditions: Lung Neoplasms
Interventions: DEVICE: Low-frequency Rotating Magnetic Therapy System|DRUG: Systemic anti-tumor therapy|DEVICE: Sham Low-frequency Rotating Magnetic Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population The Zhuiguang Trial
Status: WITHDRAWN
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DEVICE: DSLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker Research Study for PF-03084014 in cHEmoresistant Triple-negative Breast cAncer
Status: WITHDRAWN
Conditions: Breast Cancer
Interventions: DRUG: PF-03084014|PROCEDURE: Breast cancer surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6 Month Study to Evaluate the Safety, Analgesic Efficacy of ACUVAIL™ (Ketorolac Tromethamine Ophthalmic Solution) 0.45%, in Post-PRK Corneal Wound Healing
Status: COMPLETED
Conditions: Must be PRK Candidate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Questionnaire for Endoscopic Prediction Improvement of Gastrointestinal Cancer
Status: UNKNOWN
Conditions: Early Detection of Cancer
Interventions: OTHER: Result masking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Trial of Colistin Versus Meropenem in Ventilator-associated Pneumonia (VAP) (CR-GNB)
Status: COMPLETED
Conditions: Ventilator-associated Bacterial Pneumonia
Interventions: DRUG: Colistin|DRUG: Meropenem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulated Expiratory Breathing Method During Childbirth
Status: COMPLETED
Conditions: Childbirth
Interventions: DEVICE: expiration mouthpiece used during breathing exercises to ensure a constant ventilatory flowrate.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Parental Satisfaction of Hall Technique Versus SDF in the Management of Carious Primary Molars
Status: UNKNOWN
Conditions: Caries
Interventions: DRUG: Silver diamine fluoride|DEVICE: Hall technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gluten-free Oats and Gastrointestinal Health in Coeliac Disease, Part 1
Status: COMPLETED
Conditions: Unidentified Gastrointestinal Symptoms Following Gluten-free Oats Consumption
Interventions: OTHER: Gluten free oats and gastrointestinal health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: DNA-mutation Analysis in Cyst Fluid of Suspected Intraductal Papillary Mucinous Neoplasia of the Pancreas
Status: COMPLETED
Conditions: Pancreas Cyst
Interventions: DIAGNOSTIC_TEST: Next Generation Sequencing|DIAGNOSTIC_TEST: CEA and lipase|DIAGNOSTIC_TEST: Cytology|DIAGNOSTIC_TEST: Histology of resected pancreas cyst
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
Status: UNKNOWN
Conditions: Chronic Fatigue Syndrome
Interventions: OTHER: Acupuncture|OTHER: moxibustion|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study in Healthy Men and Women to Compare Two Pharmaceutical Formulations of Flupentixol/Melitracen (Deanxit®)
Status: COMPLETED
Conditions: Healthy Men and Women
Interventions: DRUG: Flupentixol/melitracen film-coated tablet|DRUG: Flupentixol/melitracen coated tablet (Deanxit®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety, Tolerability and Efficacy of Dronabinol, for the Treatment of Nausea and Vomiting in Familial Dysautonomia
Status: WITHDRAWN
Conditions: Nausea|Vomiting|Familial Dysautonomia
Interventions: DRUG: Dronabinol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Single Ascending Dose of LEM-S401 in Healthy Participants
Status: COMPLETED
Conditions: Cicatrix|Scar Prevention
Interventions: DRUG: LEM-S401|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Celiprolol Versus Ditiazem for the Prevention of Postoperative Cardiac Arrythmias in Thoracic Surgery
Status: UNKNOWN
Conditions: Postoperative Cardiac Complication
Interventions: DRUG: Celiprolol|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Postoperative Analgesia After Laparoscopic Living Donor Nephrectomy
Status: COMPLETED
Conditions: Living Donors
Interventions: DRUG: Pregabalin|DRUG: Sugar pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System
Status: COMPLETED
Conditions: Hearing Loss|Ear Diseases|Hearing Disorders|Otolaryngological Disease
Interventions: DEVICE: Remote Fitting|DEVICE: In-Office Fitting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Myofascial Release and Mobilization With Impulse Technique Torsion in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Chronic Disease
Interventions: OTHER: Myofascial Soft Tissue Release|OTHER: Mobilization with impulse technique.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Lupus Disease: Serial Biomarker Sampling in Patients With Active Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: OTHER: Group B SLE one blood donation|OTHER: Blood drawing only Group C|DRUG: Group A SLE prospective study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacious Iron for Iron Deficiency Anemia in Adults Aged ≥18 Years
Status: ENROLLING_BY_INVITATION
Conditions: Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Ferrous Fumarate|DIETARY_SUPPLEMENT: Polysaccharide Iron|DIETARY_SUPPLEMENT: Ferrous Ascorbate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Double-masked, Randomized, Placebo-controlled,Pilot Study of Diquafosol Tetrasodium in Subjects Following Photorefractive Keratectomy (PRK)
Status: TERMINATED
Conditions: Photorefractive Keratectomy
Interventions: DRUG: diquafosol tetrasodium ophthalmic solution 2%|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of mHealth Intervention on Health Empower of Overweight and Obese Women's Body Weight During Pregnancy
Status: COMPLETED
Conditions: Overweight and Obese Pregnant Women
Interventions: BEHAVIORAL: empowerment program with mHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Cervidil for Outpatient Pre-induction of Cervical Ripening
Status: TERMINATED
Conditions: Induction of Labor Affected Fetus / Newborn
Interventions: DRUG: Outpatient Dinoprostone 10mg|DRUG: Inpatient Dinoprostone 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study in Cystic Fibrosis Patients Using TOBI® PODHALER® or Other FDA Approved Inhaled Antipseudomonal Antibacterial Drugs
Status: COMPLETED
Conditions: Pseudomonas Aeruginosa in Cystic Fibrosis
Interventions: DRUG: TOBI® PODHALER®|DRUG: TOBI®|DRUG: Bethkis®|DRUG: Cayston®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: ketoconazole|DRUG: lenalidomide|DRUG: therapeutic hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Processing Therapy to Treat PTSD and Sexually Transmitted Infections Among Men Who Have Sex With Men
Status: NOT_YET_RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Randomized Controlled Trial: Induction of Labour of Obese Women With Dinoprostone or Single Balloon Catheter
Status: COMPLETED
Conditions: Obesity|Pregnancy|Labor, Induced
Interventions: DRUG: Dinoprostone|DEVICE: Single balloon foley catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of the Safety and Pharmacokinetics of GSK1363089 (Formerly XL880) Administered Orally to Subjects With Solid Tumors
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: GSK1363089
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observation, Combination Chemotherapy, Radiation Therapy, and/or Autologous Stem Cell Transplant in Treating Young Patients With Neuroblastoma
Status: UNKNOWN
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide phosphate|DRUG: ifosfamide|DRUG: isotretinoin|DRUG: melphalan|DRUG: topotecan hydrochloride|DRUG: vincristine sulfate|DRUG: vindesine|PROCEDURE: autologous hematopoietic stem cell transplantation|PROCEDURE: conventional surgery|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: iobenguane I 131|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Luxembourgish Fiber Cohort
Status: COMPLETED
Conditions: Dietary Fiber|Gastrointestinal Microbiome|Healthy Volunteers
Interventions: DIETARY_SUPPLEMENT: High Fiber Diet Intervention|DIETARY_SUPPLEMENT: Low Fiber Diet Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficiency of Use of Baracetinib in Treatment of Lupus Nephritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Lupus Nephritis
Interventions: DRUG: Anti JAK1,2|DRUG: Cyclophosphamid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety and Efficacy of GB1211 (a Galectin-3 Inhibitor) in Combination With Atezolizumab in Patients With Non-Small Cell Lung Cancer (NSCLC).
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: GB1211|DRUG: Placebo|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT