pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study of IRESSA Treatment Beyond Progression in Addition to Chemotherapy Versus Chemotherapy Alone
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Gefitinib|DRUG: Placebo|DRUG: Pemetrexed|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Kidney Injury in Severe Trauma
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DIAGNOSTIC_TEST: Neutrophil gelatinase-associated lipocalin (NGAL)|DIAGNOSTIC_TEST: Arterial lactate|DIAGNOSTIC_TEST: Interleukin-6 (IL-6)|DIAGNOSTIC_TEST: Procalcitonin (PCT)|DIAGNOSTIC_TEST: Myoglobin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sildenafil (Viagra) for the Treatment of Dyskinesias in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PrePhage - Faecal Bacteriophage Transfer for Enhanced Gastrointestinal Tract Maturation in Preterm Infants
Status: RECRUITING
Conditions: Necrotizing Enterocolitis|Microbial Substitution
Interventions: OTHER: Fecal Filtrate Transfer|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks
Status: ENROLLING_BY_INVITATION
Conditions: Ankle Block|Foot Surgery
Interventions: DRUG: Mepivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ENhance Initiation and Retention in Isoniazid Preventive Therapy (IPT) Care for HIV Study (ENRICH Study)
Status: COMPLETED
Conditions: HIV|Tuberculosis
Interventions: BEHAVIORAL: Combination intervention components|DRUG: Isoniazid Prevention Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study to Identify the Optimal Adjuvant Combination Scheme of Ipilimumab and Nivolumab in Melanoma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Skin Melanoma
Interventions: PROCEDURE: Surgery of the tumor|DRUG: Infusion with ipilimumab 3 mg/kg q3wks|DRUG: Infusion with nivolumab 1 mg/kg q3wks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Leptomeningeal Metastases
Interventions: DRUG: Pemetrexed|DRUG: Dexamethasone|DRUG: Folic Acid|DRUG: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dilantin Levels With Continuous Delivery of Enteral Feedings - A Pilot Study
Status: TERMINATED
Conditions: Seizures
Interventions: DRUG: Phenytoin (Dilantin) levels during change in enteral feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Medtronic PrimeADVANCED Neurostimulator|DEVICE: Medtronic PrimeADVANCED Neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Two Doses of Nitric Oxide (NO) Given Intermittently Via Inhalation to Subjects With Bronchiolitis
Status: COMPLETED
Conditions: Bronchiolitis Acute
Interventions: DRUG: Nitric Oxide|OTHER: Standard Supportive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of V419 (PR51) in Combination With MCC in Infants and Toddlers (V419-011)
Status: COMPLETED
Conditions: Neisseria Meningitidis|Bacterial Infections|Virus Diseases
Interventions: BIOLOGICAL: V419|BIOLOGICAL: PREVNAR 13®|BIOLOGICAL: MCC-TT|BIOLOGICAL: MCC-CRM|BIOLOGICAL: Hib-MCC|BIOLOGICAL: MMR Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Feasibility and Safety of a Three-Port Laparoscopic Cholecystectomy Using a 2-mm Mini-Instrument
Status: COMPLETED
Conditions: Gallbladder Disease
Interventions: PROCEDURE: 2- mini-instrument
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Surface Disease Changes After iStent or iStent Inject Implantation With Phacoemulsification
Status: COMPLETED
Conditions: Ocular Surface Disease|Glaucoma, Open-Angle
Interventions: DEVICE: iStent or iStent inject implantation with concomitant cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on a Live-attenuated Respiratory Syncytial Virus Vaccine for Assessment of Safety, Transmissibility, and Genetic Stability of the Vaccine Virus Among Close Contacts in Infants and Toddlers 6 to < 24 Months of Age in Puerto Rico (USA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Infection
Interventions: BIOLOGICAL: RSVt Vaccine|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reactive Balance Training for Fall Prevention
Status: RECRUITING
Conditions: Healthy Young|Healthy Aging|Stroke
Interventions: OTHER: Experimental: Treadmill training|OTHER: Experimental: Overground training|OTHER: Experimental: Surefooted training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of ABC294640 (Yeliva ®) Alone and in Combination With Hydroxychloroquine Sulfate in Treatment of Patients With Advanced Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma|Cholangiocarcinoma Non-resectable|Cholangiocarcinoma, Perihilar|Cholangiocarcinoma, Extrahepatic|Cholangiocarcinoma, Intrahepatic
Interventions: DRUG: ABC294640|DRUG: Hydroxychloroquine Sulfate 200 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Emotion and Cognition Abilities of Children With PWS and Proposition of an Innovative Remediation
Status: COMPLETED
Conditions: Prader-Willi Syndrome
Interventions: BEHAVIORAL: Questionnaires|DEVICE: t-VNS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Post-Market Registry to Evaluate the Safety and Efficacy of the The SUPRAFLEX CRUZ™ Sirolimus Eluting Coronary Stent System in the Treatment of an Octo- and Nonagenerian All-Comer Patient Cohort With Coronary Artery Disease - the Cruz Senior Study
Status: RECRUITING
Conditions: Coronary Disease
Interventions: DEVICE: The SUPRAFLEX CRUZ™ Sirolimus eluting coronary stent system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: BMS-986435|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Comparison of the Effectiveness of Two Moisture Insensitive Primers on Orthodontic Attachment Bond
Status: UNKNOWN
Conditions: Dental Bonding
Interventions: OTHER: Single intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Aspergillosis Detection Via EBC-GM in Ventilated Patients
Status: COMPLETED
Conditions: Bronchoalveolar Lavage Fluid|Sensitivity and Specificity|Critical Illness|Respiration Failure|Respiratory Fungal Infection|Exhaled Breath Condensate|Aspergillosis, Invasive Pulmonary
Interventions: OTHER: Compare the levels of Galactomannan (GM) levels in exhaled breath condensate (EBC) and BALF
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Triple Therapy Versus Quadruple Therapies in the First Line Therapy of Helicobacter Pylori Infection
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: triple, quadruple, non-bismuth quadruple therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Kinerase Pro+Therapy Regimen Vs. Kinerase Vs. Control for the Treatment of Skin Aging
Status: TERMINATED
Conditions: Skin Aging
Interventions: DRUG: Kinerase Pro+Therapy Line day repair, serum, night repair|DRUG: Kinerase Pro+Therapy Line Ultra rich day repair|DRUG: LubriDerm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose:
Clinical trial: Centralized Reading Assessment of Chronic CerebroSpinal Venous Insufficiency (CCSVI) in Patients With Multiple Sclerosis and Other Neurological Diseases
Status: COMPLETED
Conditions: Clinically Isolated Syndrome (CIS)|Multiple Sclerosis (MS)|Other Neurological Disorders (OND)|Healthy (HC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of Antenatal Corticosteroid Therapy on Postnatal Surfactant Use in Preterm Infants
Status: COMPLETED
Conditions: Hyaline Membrane Disease (HMD)
Interventions: OTHER: Impact of antenatal corticosteroid therapy on surfactants use postnatal
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: zoledronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PORH and Response to Cold in Raynaud's Phenomenon.
Status: UNKNOWN
Conditions: Raynaud Disease|Hyperemia|Cold
Interventions: PROCEDURE: post-occlusive hyperemia|PROCEDURE: cooling box|DRUG: L-NMMA and Fluconazole dermic injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study
Status: TERMINATED
Conditions: Intra-abdominal Abscess
Interventions: DRUG: Cathflo (Alteplase)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Wearable Tech to Increase Physical Activity in Inpatient Rehabilitation for Overweight and Obese Patients
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DEVICE: Wearable tech with feedback|DEVICE: Wearable tech without feedback|BEHAVIORAL: Rehabilitation program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open-Label Trial of Sulforaphane in Premutation Carriers With FXTAS
Status: COMPLETED
Conditions: Fragile X Associated Tremor/Ataxia Syndrome (Fxtas) (Diagnosis)
Interventions: DIETARY_SUPPLEMENT: Sulforaphane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Topical Challenge With Omiganan and Imiquimod in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Omiganan|DRUG: Imiquimod|DRUG: Omiganan 1% and Imiquimod|DRUG: Omiganan 2.5% and Imiquimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Comparison of Standard Fusion With "Topping Off"-System in Lumbar Spine
Status: UNKNOWN
Conditions: Spondylolisthesis|Erosive Osteochondrosis in L2-S1
Interventions: DEVICE: Topping off system|DEVICE: monosegmental PLIF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness
Status: RECRUITING
Conditions: Anxiety Disorders|Psychotic Disorders|Depressive Disorder|Psychosocial Functioning
Interventions: BEHAVIORAL: Resilience Training for Teens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Monoclonal Antibody Conditioning for Allogeneic Stem Cell Transplantation of Patients With Inherited Metabolic Storage Diseases
Status: TERMINATED
Conditions: Inherited Metabolic Storage Diseases
Interventions: DRUG: CAMPATH-1H|DRUG: Anti-CD45|DRUG: FK506|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of GLA:D Program in West Virginians With Osteoarthritis of the Knee
Status: UNKNOWN
Conditions: Osteoarthritis, Knee
Interventions: OTHER: GLA:D program (Good Life with osteoArthritis in Denmark)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Alternative HPV Vaccination Schedules in Males in a University Setting
Status: COMPLETED
Conditions: Quadrivalent HPV Vaccine|Human Papillomavirus Vaccine
Interventions: BIOLOGICAL: quadrivalent human papillomavirus vaccine|BIOLOGICAL: quadrivalent human papillomavirus vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cognitive Behavioral Therapy for Insomnia Among Different Types of Shift Workers
Status: UNKNOWN
Conditions: Chronic Insomnia|Cognitive Behavioral Therapy|Sleep Disorders, Circadian Rhythm|Sleep Disorders, Shift-Work
Interventions: BEHAVIORAL: Cognitive Behavioral Group Therapy for Insomnia|BEHAVIORAL: Cognitive Behavioral Self-help Therapy for Insomnia|BEHAVIORAL: Sleep Hygiene Guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 1st Line Treatment of Bevacizumab-Taxane vs Bevacizumab-Exemestane in Metastatic Breast Cancer
Status: TERMINATED
Conditions: First Line Metastatic Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Bevacizumab|DRUG: Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum Malaria
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Coartem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: FKC288 in Participants With Autoimmune Kidney Diseases
Status: RECRUITING
Conditions: Lupus Nephritis|ANCA-associated Vasculitis|Membranous Nephropathy - PLA2R Induced|IgG4-Related Diseases
Interventions: DRUG: FKC288
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: DIAGNOSTIC_TEST: SARS-CoV-2 Antibody Analysis|DIAGNOSTIC_TEST: Weck-cel Swab Collection|BEHAVIORAL: Web Based Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optilume™ BPH Prostatic Drug Coated Balloon Dilation Catheter
Status: ACTIVE_NOT_RECRUITING
Conditions: Benign Prostatic Hyperplasia|Benign Prostatic Hypertrophy
Interventions: DEVICE: Optilume™ BPH Prostatic DCB Dilation Catheter|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: bBeAMom: Effectiveness of a Cognitive-Behavioral Blended Intervention for Postpartum Depression
Status: UNKNOWN
Conditions: Postpartum Depression
Interventions: BEHAVIORAL: Be a Mom Coping with Depression|BEHAVIORAL: Be a Mom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Underwater Resection of Non-pedunculated Colorectal Lesions
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: PROCEDURE: Underwater resection|PROCEDURE: Conventional (gas distended colon) resection|PROCEDURE: Standard polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: White Blood Cell Signaling and Defense Mechanisms in Patients With Diabetes Mellitus Type 2 and Periodontitis
Status: UNKNOWN
Conditions: Chronic Periodontitis|Diabetes Mellitus, Type 2
Interventions: PROCEDURE: ADT+FD|PROCEDURE: FD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plerixafor Versus G-CSF in the Treatment of People With WHIM Syndrome
Status: COMPLETED
Conditions: Myelokathexis|Infections|Neutropenia|Warts|Hypogammaglobulinemia
Interventions: DRUG: Plerixafor|DRUG: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Perineural Injection With Dextrose Versus Therapy Conventional Physics in Patients With Bell's Palsy
Status: COMPLETED
Conditions: Bell´s Palsy
Interventions: PROCEDURE: inyección perineural con solución de dextrosa tamponada
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sequential Fluoroscopy Guidance With Spiral Guidance in Terms of Safety, Effectiveness, Speed and Radiation in Interventional Chest-abdomen-pelvic Procedures
Status: COMPLETED
Conditions: Body Interventional procédures With CT
Interventions: OTHER: Patients with indication of interventional percutaneous diagnostic or therapeutic chest-abdomen-pelvic procedure under CT control
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AMH Levels Change During Treatment With GnRh Agonist
Status: COMPLETED
Conditions: Uterine Fibroids|Endometriosis|Endometriosis of Uterus|Pelvic Pain
Interventions: DRUG: GnRH analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 80 Years of Age With Thyroid Eye Disease
Status: RECRUITING
Conditions: Thyroid Eye Disease
Interventions: DRUG: TOUR006 - 20 MG|OTHER: Placebo|DRUG: TOUR006 - 50 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: C1-Inhibitor (INH) for Refractory Antibody Mediated Renal Allograft Rejection
Status: COMPLETED
Conditions: Antibody Mediated Rejection of Kidney Transplant
Interventions: DRUG: C1-INH (Berinert)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Marker Monitoring of Furosemide-containing Gastroretentive Formulation in Healthy Male Subjects (Fasting and Fed Conditions)
Status: COMPLETED
Conditions: Gastroretentive Drug Formulation of Furosemide|Oedema
Interventions: DRUG: GRDF furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meditation to Reduce Caregiver Stress
Status: COMPLETED
Conditions: Depression NOS|Major Depressive Disorder|Anxiety NOS
Interventions: BEHAVIORAL: Kirtan Kriya meditation|BEHAVIORAL: Relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Safety and Pharmacokinetic Study for Dapivirine and Maraviroc Gel in Belgium
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Maraviroc/Dapivirine Gel|DRUG: Dapivirine Vaginal Gel|DRUG: Maraviroc Vaginal Gel|DRUG: Matching Placebo Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Contrast Media Temperature and Patient Comfort in CT of the Abdomen
Status: COMPLETED
Conditions: Contrast Media|Comfort|Temperature|Abdomen
Interventions: OTHER: CM Temperature (20° C)|OTHER: CM Temperature (37° C)|OTHER: Weight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Metformin|DRUG: Placebo|BEHAVIORAL: Lifestyle intervention|BEHAVIORAL: Standard printed dietary guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Spectral Filtering in a Spectrally Adjustable Ocular Photosensitivity Analyzer
Status: COMPLETED
Conditions: Photosensitivity
Interventions: OTHER: 419 nm Spectacle Filter|OTHER: 437 nm Spectacle Filter|OTHER: 456 nm Spectacle Filter|OTHER: 476 nm Spectacle Filter|OTHER: 373 nm Spectacle Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tenofovir As Prevention Of Hepatitis b Mother-to-child Transmission
Status: UNKNOWN
Conditions: Hepatitis B Chronic Infection|Pregnancy
Interventions: DRUG: Tenofovir disoproxil fumarate|DEVICE: Rapid tests HBe Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Silodosin vs Placebo in the Treatment of Female LUTS
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms
Interventions: DRUG: Silodosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Virtual Reality (VR) on Skin Prick Test Related Pain and Fear in Children
Status: COMPLETED
Conditions: Pain|Fear|Fear of Pain|Child, Only|Allergy
Interventions: BEHAVIORAL: Virtual reality (VR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.
Status: RECRUITING
Conditions: Breast Cancer Female|Breast Neoplasms
Interventions: DIAGNOSTIC_TEST: PET CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VIBration Training in EpicondylitiS
Status: UNKNOWN
Conditions: Epicondylitis|Pain|Tendinopathy
Interventions: DEVICE: Flexi-Bar vibration device only|DEVICE: Flexi-Bar + XCO-Trainer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-operative Stereotactic Body Radiation Therapy for Pancreatic Adenocarcinoma With or Without CCX872-B
Status: WITHDRAWN
Conditions: Adenocarcinoma of the Pancreas|Pancreas Cancer
Interventions: DRUG: CCX872-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories
Status: COMPLETED
Conditions: Sexual Risk Behavior|Childhood Sexual Abuse|Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: Cognitive Processing Therapy for Sexual Risk|BEHAVIORAL: Supportive Psychotherapy|BEHAVIORAL: Sexual Risk Reduction Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Motor Dual Task Versus Task Specific Training on Cognition and Motor Functioning in Stroke Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: OTHER: Dual Task Training|OTHER: Task Specific Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Magnetic Stimulation for Attention Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity (ADHD)
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham Transcranial Magnetic Stimulation (Sham TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpelisib (BYL719) in Combination With Continued Endocrine Therapy Following Progression on Endocrine Therapy in Hormone Receptor Positive, HER2 Negative, PIK3CA Mutant Metastatic Breast Cancer
Status: RECRUITING
Conditions: Hormone Receptor Positive Breast Carcinoma|HER2-negative Breast Cancer|PIK3CA Mutant Metastatic Breast Cancer
Interventions: DRUG: Alpelisib|DRUG: Fulvestrant|DRUG: Aromatase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Efalex Active 50+ on Cognitive Performance, Well-being and Cerebral Hemodynamics in Healthy Older Adults
Status: COMPLETED
Conditions: Cognitive Function|Mood|Well-being|Cerebral Blood Flow
Interventions: DIETARY_SUPPLEMENT: Efalex active 50+|DIETARY_SUPPLEMENT: DHA rich fish oil|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Gender Disparity and Hormones in Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis (CF)
Interventions: DRUG: Loestrin (norethindrone acetate and ethinyl estradiol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Comparing Calendula Officinalis With Aqueous Cream "Essex" to Treat Skin Reactions From Radiotherapy of Breast Cancer
Status: COMPLETED
Conditions: Postoperative Radiotherapy Breast Cancer
Interventions: DRUG: Calendula Weleda cream (Weleda AG, Sweden) contains extracts of marigold plant (Calendula Officinalis 10%), wool fat and sesame oil|DRUG: Essex® cream (Schering-Plough), aqueous cream without parabens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Oral Glutamine on Mitochondrial Function in CKD
Status: COMPLETED
Conditions: Cardiovascular Disease|Sarcopenia|Endothelial Dysfunction|Muscle Mitochondrial Function|Kidney Disease
Interventions: DIETARY_SUPPLEMENT: First Intervention (14 days)|OTHER: Washout (3 weeks)|DIETARY_SUPPLEMENT: Second Intervention (14 days)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Opioid-refractory Pain (WHO Level III) by Pituitary Radiosurgery
Status: UNKNOWN
Conditions: Any Cancer With Multiple Bone Metastases
Interventions: DEVICE: GammaKnife®|DEVICE: 18F-2-fluoro-2-deoxy-D-glucose - positron emission tomography (FDG-PET)|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FC Patch Low: Metabolism Study
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Gestodene/EE Patch (BAY86-5016)|DRUG: EE/Levonorgestrel (Microgynon, BAY86-4977)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dexamethasone Intravitreal Implant (Ozurdex®) for Recurrent Vogt-Koyanagi-Harada (VKH) Disease Posterior Uveitis
Status: COMPLETED
Conditions: Posterior Uveitis
Interventions: DRUG: Dexamethasone Ophthalmic implant
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Sequential CFA vs CFA +rFSH for Elective Fertility Preservation.
Status: RECRUITING
Conditions: Fertility
Interventions: DRUG: 150μg CFA (Elonva®) at stimulation day (SD) 1 and 100μg CFA(Elonva®) at SD 5|DRUG: 150μg CFA (Elonva®) at SD 1 following by rFSH (Puregon®) 200IU daily from SD 8 until the day of the trigger
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Invasive Physical Therapy Protocol in Primary Care Patients With Low Back Pain. Randomized Controlled Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Low Back Pain
Interventions: OTHER: Invasive Physiotherapy Group|OTHER: Sham Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Patients With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fecal Transplant +/- Gut Decontamination in Preventing Acute Graft Versus Host Disease in Patients Given Broad-Spectrum Antibiotics
Status: WITHDRAWN
Conditions: Graft-versus-host Disease Prevention
Interventions: OTHER: Best Practice|PROCEDURE: Fecal Microbiota Transplantation|DRUG: Nystatin|DRUG: Piperacillin-Tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
Status: RECRUITING
Conditions: Liver Diseases|Liver Fibrosis
Interventions: DIAGNOSTIC_TEST: Liver biopsy - percutaneous|DIAGNOSTIC_TEST: Liver biopsy - transjugular|DIAGNOSTIC_TEST: liver biopsy - EUS guided
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Infusion of ARI-0001 Cells in Patients With CD19 + Acute Lymphoid Leukemia Resistant or Refractory to Therapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoid Leukemia
Interventions: DRUG: ARI-0001 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals
Status: UNKNOWN
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2|COVID-19|Acute Respiratory Distress Syndrome|ARDS|Hypoxemic Respiratory Failure
Interventions: PROCEDURE: Prone Positioning (PP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of a Single-Dose and Repeat-Administration of Intranasal Esketamine on On-Road Driving in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: Placebo (Intranasal)|DRUG: Esketamine|OTHER: Alcohol|DRUG: Placebo (Oral)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Diphenylcyclopropenone (DPCP) as a Depigmenting Therapy in Extensive Vitiligo
Status: COMPLETED
Conditions: Vitiligo
Interventions: DRUG: diphenylcyclopropenone (DPCP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loop Drainage: Effectiveness in Treating Cutaneous Abscesses
Status: TERMINATED
Conditions: Abscess of Skin and/or Subcutaneous Tissue
Interventions: PROCEDURE: Traditional Incision and Drainage.|PROCEDURE: Loop drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vibration Arthrometry Between Patella Resurfacing and Patella Non-resurfacing in Total Knee Replacement Patients
Status: COMPLETED
Conditions: Patellar Crepitus|Vibroacoustic Signal
Interventions: PROCEDURE: patellar resurfacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Lifileucel (LN-144), Autologous Tumor Infiltrating Lymphocytes, in the Treatment of Patients With Metastatic Melanoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Lifileucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repisodic & Skilled Nursing Facility Preferred Provider Networks
Status: COMPLETED
Conditions: Skilled Nursing Facilities|Behavioral Economics
Interventions: BEHAVIORAL: Order of Options|BEHAVIORAL: Default Option
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study Comparing the Efficacy and Safety of ABT-652 to Placebo in Subjects With Diabetic Neuropathic Pain
Status: TERMINATED
Conditions: Diabetic Neuropathic Pain
Interventions: DRUG: ABT-652 6 mg|DRUG: ABT-652 12 mg|DRUG: ABT-652 12 mg - 18 mg|DRUG: Placebo|DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of STARgraft-2 for Hemodialysis Access
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DEVICE: Implant of STARgraft-2 shunt in the upper arm and subsequent use for hemodialysis access
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of AZD8154 Concentrations in Blood
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: AZD8154 nebuliser|DRUG: AZD8154 Monodose DPI presented in capsules|DRUG: AZD8154 Placebo Monodose DPI presented in capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: carmustine|DRUG: erlotinib hydrochloride|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tislelizumab Combined With Fruquintinib and SBRT as Athird-line and Posterior Line Treatment in Patients With Advanced CRC
Status: UNKNOWN
Conditions: Patients With Advanced Metastatic Colorectal Cancer
Interventions: DRUG: Tislelizumab plus Fruquintinib and SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety Evaluation of HCP1202 in COPD Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: HCP1202|DRUG: HGP1011|DRUG: HCP0910
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gefitinib 500mg Versus 250mg in Patients With NSCLC With Stable Disease After a Month Treatment of Gefitinib 250mg
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Gefitinib 500mg/Gefitinib 250mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents
Status: UNKNOWN
Conditions: Traumatic Brain Injury|Intracranial Hypertension
Interventions: DRUG: cisatracurium besilate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propofol-fentanyl and Midazolam-fentanyl for Conscious Sedation
Status: UNKNOWN
Conditions: Emergencies
Interventions: DRUG: Propofol|DRUG: Midazolam|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Saxagliptin in Adult Indian Patients With Type 2 Diabetes Inadequate Glycemic Control
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Abciximab Bolus Only Regimen in Providing Inhibition of Platelet Action Over Time
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: bolus+infusion|DRUG: abciximab bolus only regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Status: COMPLETED
Conditions: Patients|Anxiety Disorders
Interventions: DRUG: LSD|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults
Status: COMPLETED
Conditions: Aging
Interventions: DRUG: Orally active growth hormone secretagogue (MK-677)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The COVID-19 Pandemic and Exercise Study
Status: COMPLETED
Conditions: Depressive Symptomatology|Psychological Distress|Health Behavior
Interventions: BEHAVIORAL: Yoga group|BEHAVIORAL: High Intensity Interval Training group|BEHAVIORAL: Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Trial to Investigate the Efficacy and Safety of NuSepin® in COVID-19 Pneumonia Patients
Status: COMPLETED
Conditions: COVID19 Pneumonia
Interventions: DRUG: NuSepin® 0.1 mg|DRUG: NuSepin® 0.2 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sirolimus-Eluting, Heparin-Coated CoCr Stent in the Treatment of de Novo Coronary Artery Lesions in Small Vessels(EVOLUTION)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: SIROLIMUS-ELUTING, HEPARIN-COATED CoCr BALLOON-EXPANDABLE STENT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Infection Control Measures for Patients Undergoing Percutaneous Nephrolithotomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Urological Nursing|Kidney Stone
Interventions: BEHAVIORAL: Infection control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effect of an Inpatient Home-work Exercise Program on Leg Function After Stroke
Status: COMPLETED
Conditions: Cerebrovascular Accident (Stroke)
Interventions: BEHAVIORAL: Leg Exercise Program|BEHAVIORAL: Leg Management group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Impact of Mindfulness Based Stress Reduction on Anxiety, Depression and QOL in Women With Intrauterine Adhesion.
Status: COMPLETED
Conditions: Asherman Syndrome
Interventions: OTHER: Mindfulness Based Stress Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Topotecan and Paclitaxel in Treating Patients With Advanced Non-small Cell Lung Cancer or Other Advanced Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Metrics Based Performance Based Progression in Provision of Labor Epidural Analgesia
Status: COMPLETED
Conditions: Labor Pain
Interventions: BEHAVIORAL: Training to proficiency|BEHAVIORAL: Conventional training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea
Status: ENROLLING_BY_INVITATION
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Xultophy® (insulin degludec/liraglutide)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Two Compression Methods in the Treatment of Upper Limb Lymphedema
Status: COMPLETED
Conditions: Lymphedema
Interventions: DEVICE: Precast Adjustable Compression Wrap (Circaid)|DEVICE: Multilayer Compression Bandages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
Status: UNKNOWN
Conditions: Hip Fractures
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma|Melanoma Stage IV|Breast Cancer|Prostate Cancer|Glioblastoma Multiforme|GBM|Brain Cancer|Metastatic Breast Cancer|Metastatic Melanoma|Metastatic Prostate Cancer|Melanoma Recurrent|Prostate Cancer Metastatic|Recurrent Glioblastoma|Newly Diagnosed Glioblastoma
Interventions: DRUG: ST101|DRUG: Temozolomide|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists
Status: COMPLETED
Conditions: Melanoma|Metastatic Melanoma|Mucosal Melanoma
Interventions: BIOLOGICAL: Peptide Vaccine (LPV7) + Tetanus peptide|OTHER: PolyICLC|OTHER: Resiquimod|OTHER: IFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Multifactorial Intervention to Improve Diet and Physical Activity in Diabetics From Primary Care
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Intervention group|OTHER: Control: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of T-shaped Toothbrush
Status: COMPLETED
Conditions: Oral Hygiene
Interventions: BEHAVIORAL: Brushing demonstration using T shaped toothbrush|BEHAVIORAL: Brushing demonstration using conventional toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION