pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: TRx0014 in Patients With Mild or Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Dementia, Alzheimer Type
Interventions: DRUG: TRx0014|DRUG: TRx0014|DRUG: Placebo|DRUG: TRx0014
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Pacing Mode and Diastolic Function on Cardiac Output
Status: COMPLETED
Conditions: Diastolic Function|Cardiac Output|Pacemaker Stimulation Mode|Stroke Volume|AV Block
Interventions: OTHER: Pacemaker stimulation mode
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis
Status: RECRUITING
Conditions: Adenomatous Polyposis Coli|Familial Adenomatous Polyposis|Duodenal Adenoma
Interventions: DEVICE: low energy argonplasma coagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Observational, Single Centre Study to Assess the Feasibility of the Data Harvested by the Acorai Intracardiac Pressure Monitoring (ICPM) System in Predicting Prognosis in Patients Discharged From Hospital After Treatment for Acute Decompensated Heart Failure
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Decompensated Heart Failure
Interventions: DEVICE: Acorai ICPM system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Controlled Clinical Trial of Internal Fixation of Intertrochanteric Fractures of Femur Guided by Conventional Versus IF-AI Artificial Intelligence Program
Status: NOT_YET_RECRUITING
Conditions: Hip Fractures
Interventions: PROCEDURE: Surgical protocol guided by artificial intelligence software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of IMSI in Poor Responders to IVF
Status: TERMINATED
Conditions: Female Infertility
Interventions: PROCEDURE: Intra-cytoplasmic Sperm Injection|PROCEDURE: Intra-cytoplasmic Morphologically-selected Sperm Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: hUC Mesenchymal Stem Cells (19#iSCLife®-LC) in the Treatment of Decompensated Hepatitis b Cirrhosishepatitis b Cirrhosis
Status: RECRUITING
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Peripheral iv
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liga Sure Versus Conventional Suture Ligature for Decrease Blood Loss During Abdominal Hysterectomy
Status: COMPLETED
Conditions: Decrease Blood Loss During Abdominal Hysterectomy
Interventions: PROCEDURE: conventional suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Behavioural Profiling of Disease-related Cognitive and Motor Impairment in PD
Status: COMPLETED
Conditions: Parkinson Disease|Medication|UPDRS|Motor Function|Cognitive Impairment|Depression|Impulsive|Levodopa
Interventions: DRUG: Levodopa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Diabetic Foot Ulcer
Interventions: OTHER: Standard of Care: Moist Wound Therapy and Offloading|OTHER: EpiFix plus Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Placement of a Diazepam Suppository on Early Postoperative Pain Following Pelvic Reconstructive Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Diazepam|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Reduced Toxicity Myeloablative Conditioning Regimen for Wiskott-Aldrich Syndrome (WAS)
Status: COMPLETED
Conditions: Wiskott-Aldrich Syndrome
Interventions: DRUG: Fludarabine, Busulfan, Thymoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
Status: TERMINATED
Conditions: Full- Thickness Massive RCT (MRCT) of at Least 5 cm in Diameter Including Fatty Infiltration Grade III or IV
Interventions: DEVICE: Best Repair of torn Rotator Cuff|DEVICE: InSpace™ system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Incision Pain and Uterine Contraction Pain After Cesarean Section
Status: UNKNOWN
Conditions: C.Delivery; Surgery (Previous), Gynecological
Interventions: DRUG: Group SF1|DRUG: Group S1|DRUG: Group SF2|DRUG: Group S2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Orelabrutinib and Obinutuzumab Plus FC Regimen in Treating Newly Diagnosed CLL/SLL
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions: DRUG: Orelabrutinib|DRUG: Obinutuzumab|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Treatment Based on Organ-like Culture
Status: UNKNOWN
Conditions: Breast Cancer Organoids
Interventions: DRUG: Trastuzumab|DRUG: Doxorubicin Hydrochloride|DRUG: Epirubicin hydrochloride|DRUG: Fluorouracil|DRUG: Paclitaxel|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Recombinant Human Endostatin|DRUG: Pirarubicin hydrochloride|DRUG: Pyrrolidine|DRUG: Ixabepilone|DRUG: Tamoxifen citrate|DRUG: Vinorelbine tartrate|DRUG: Carboplatin|DRUG: Methotrexate|DRUG: Eribulin mesylate|DRUG: Toremifene citrate|DRUG: Anastrozole|DRUG: Letrozole|DRUG: Exemestane|DRUG: Fulvestrant|DRUG: Olaparib|DRUG: Bevacizumab|DRUG: Apatinib mesylate|DRUG: Pattozumab|DRUG: Capecitabine|DRUG: Ear particles|DRUG: Aidi Injection|DRUG: Cyclophosphamide
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Bioequivalence Study of APX001 High-load and Low-load Tablets
Status: COMPLETED
Conditions: Invasive Fungal Infections
Interventions: DRUG: APX001|DRUG: APX001A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of Olaparib in Combination With Paclitaxel to Treat Advanced Gastric Cancer.
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Olaparib|DRUG: Paclitaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Stage II or Stage III Colon Cancer That Has Been Removed During Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: BCG vaccine|BIOLOGICAL: autologous tumor cell vaccine|DRUG: fluorouracil|DRUG: leucovorin calcium|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Predictors of Neonatal Necrotizing Enterocolitis
Status: COMPLETED
Conditions: Necrotising Enterocolitis
Interventions: DIAGNOSTIC_TEST: Serum γ-Glutamyl transferase (GGT), Total serum bilirubin (TSB), Serum calcium concentration (Ca2+), Peripheral blood neutrophil to lymphocyte ratio (NLR)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Spray and Stretch on Postneedling Soreness and Sensitivity After Dry Needling of a Latent Myofascial Trigger Point.
Status: COMPLETED
Conditions: Pain After Dry Needling
Interventions: OTHER: Spray and stretch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation for Refractory Pain in Erythromelalgia
Status: RECRUITING
Conditions: Erythromelalgia
Interventions: PROCEDURE: Burst Spinal Cord Stimulation|PROCEDURE: Sham spinal cord stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in Patients With Uncontrolled Hypertension (Symplicity HTN-2)
Status: COMPLETED
Conditions: Uncontrolled Hypertension
Interventions: DEVICE: Renal Denervation (Symplicity® Renal Denervation System)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VEGF-targeted Fluorescence Near-Infrared (NIR) Endoscopy in (Pre)Malignant Esophageal Lesions
Status: COMPLETED
Conditions: Esophageal Cancer|Dysplasia
Interventions: DRUG: Bevacizumab-IRDye800CW|DEVICE: Near infrared fluorescence endoscopy platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Low/No Calorie Sweeteners on Glucose Tolerance
Status: COMPLETED
Conditions: Healthy Population|Glucose Tolerance
Interventions: OTHER: Low/No Calorie Sweeteners|OTHER: Placebo Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Study to Evaluate the Durability of Response Study of CTP-543 in Adult Patients With Moderate to Severe Alopecia Areata
Status: COMPLETED
Conditions: Alopecia Areata
Interventions: DRUG: CTP-543|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Using Mobile App on Perceived Stress During COVID-19 Pandemic
Status: COMPLETED
Conditions: Perceived Stress|Anxiety|Sleep Disturbance
Interventions: OTHER: "Calm" is a mindfulness meditation mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-40411813 in Male and Female Elderly Patients
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: JNJ-40411813 50 mg|DRUG: JNJ-40411813 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy Applications on the Hip and Defined Functional Parameters in Children With Developmental Hip Dysplasia
Status: NOT_YET_RECRUITING
Conditions: Exercise|Developmental Dysplasia of the Hip
Interventions: BEHAVIORAL: Physical Therapy and Rehabilitation Modalities|BEHAVIORAL: Conventional Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Primary Graft Dysfunction, Pronation, Bilateral Lung Transplants
Status: COMPLETED
Conditions: Lung Transplant|Primary Graft Dysfunction
Interventions: PROCEDURE: Supine positioning|PROCEDURE: Early pronation|PROCEDURE: Late pronation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Talactoferrin Oral Solution for Nosocomial Infection in Preterm Infants
Status: UNKNOWN
Conditions: Nosocomial Infections
Interventions: DRUG: Talactoferrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Peppermint Oil in Cardiometabolic Outcomes
Status: COMPLETED
Conditions: Cardiometabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Peppermint oil.|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Randomized Study of Nasal High Flow in Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Lung Diseases, Obstructive
Interventions: DEVICE: Nasal high flow cannula (Fisher & Paykel Healthcare, Auckland, New Zealand)|DEVICE: nasal catheter or Venturi mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.
Status: NOT_YET_RECRUITING
Conditions: Lung Diseases|Carcinoma, Non-Small-Cell Lung|Resectable Lung Non-Small Cell Carcinoma
Interventions: DRUG: Zimberelimab|DRUG: Sacituzumab govitecan|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer
Status: WITHDRAWN
Conditions: Metastatic Pancreatic Cancer|Pancreatic Cancer|Pancreas Cancer|Pancreatic Adenocarcinoma Resectable|Pancreatic Ductal Adenocarcinoma|Pancreatic Metastasis
Interventions: DRUG: Ascorbic Acid|DRUG: Paclitaxel protein-bound|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Elastography for Assessment of Liver Fibrosis (MK-0000-132)(COMPLETED)
Status: COMPLETED
Conditions: Liver Fibrosis|Hepatitis C Virus
Interventions: PROCEDURE: MRE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Visual Information Processing in Schizophrenia Patients With Visual Hallucinations
Status: UNKNOWN
Conditions: Schizophrenia|Visual Hallucination|Auditory Hallucination|False Perception
Interventions: OTHER: behavioral task : emotional priming
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 64Cu-TLX592 Phase I Safety, PK, Biodistribution and Dosimetry Study (CUPID Study)
Status: COMPLETED
Conditions: Metastatic Prostate Cancer
Interventions: DRUG: 64Cu-DOTA-TLX592
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of BI 671800 HEA in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 671800 HEA delayed release (enteric coated) tablet|DRUG: BI 671800 HEA solution|DRUG: BI 671800 HEA particulate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study on Optimizing Treatment for ABPA
Status: UNKNOWN
Conditions: Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Prednisone tablet|DRUG: itraconazole|BIOLOGICAL: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Rofecoxib Versus Placebo and Diclofenac in Patients With Acute Painful Rotator Cuff Syndrome
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: MK0966; rofecoxib|DRUG: Comparator: diclofenac, placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preemptive Analgesia With Intravenous Paracetamol for Post-cesarean Section Pain Control
Status: COMPLETED
Conditions: Cesarean Section; Dehiscence
Interventions: DRUG: paracetamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting
Status: RECRUITING
Conditions: Dyspepsia
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Theories of Working Memory and Consolidation/RECOnsolidation in the Process of Resorption of Post-traumatic Symptoms.
Status: NOT_YET_RECRUITING
Conditions: Working Memory|Consolidation/Recconsolidation Memory|Eye Movement Desensitization and Reprocessing|Alterning Bilateral Stimulation|Stress Disorders, Post-Traumatic|Intrusive Memories|Vividness|Emotivity
Interventions: BEHAVIORAL: Eye movements (EM)|BEHAVIORAL: Auditory stimulations|BEHAVIORAL: Tactile stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Assess the Risk of Out-of-Hospital Sudden Cardiac Death in Users of Domperidone, Users of Proton Pump Inhibitors, and Users of Metoclopramide
Status: COMPLETED
Conditions: Death, Sudden, Cardiac
Interventions: DRUG: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency
Status: COMPLETED
Conditions: Childhood-onset Growth Hormone Deficiency|Pituitary Dwarfism
Interventions: BIOLOGICAL: recombinant human growth hormone|BIOLOGICAL: recombinant human growth hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exclusion Diet for Crohn's Disease Plus Enteral Nutrition on Children and Adolescents With Crohn's Disease
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Diseases
Interventions: DIETARY_SUPPLEMENT: formula|BEHAVIORAL: exclusion diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Brain-derived Neurotrophic Factor (BDNF) Single Nucleotide Gene Polymorphism and Nerve Growth Factor as Risk Factors That Increase Severity of Allergic Rhinitis
Status: RECRUITING
Conditions: Allergic Rhinitis
Interventions: DIAGNOSTIC_TEST: Genotyping.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Type II Pediatric Supracondylar Humerus Fracture Management and Outcomes: A Prospective Multi-centre Cohort Study
Status: UNKNOWN
Conditions: Trauma|Fracture;Elbow
Interventions: PROCEDURE: Closed reduction and percutaneous pinning and immobilization|PROCEDURE: Non-operative reduction and immobilization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ablating Atrial Tachycardias Occuring During Ablation of Complex Fractionated Electrograms in Persistent AF
Status: COMPLETED
Conditions: Atrial Fibrillation|Ablation|Atrial Flutter
Interventions: PROCEDURE: Ablation|PROCEDURE: Cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Interventional (Observational) Post-Authorization Safety Study of HES 130/0.42 in Paediatric Patients
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: HES 130 / 0.42 (Venofundin 6%, Tetraspan 6%)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Preconditioning With Sevoflurane During Organ Procurement From Brain Dead Donors: Impact on Early Function of Liver Allografts
Status: UNKNOWN
Conditions: Post-transplantation Liver Allograft Function
Interventions: DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Hydrolysed Red Ginseng Extract on Improvement of Hyperglycemia
Status: UNKNOWN
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Hydrolysed Red Ginseng Extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Adventitia Reserved and Anatomical Implant Technique of Transvaginal Mesh Procedure for Pelvic Organ Prolapse
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: TVM using the Vaginal Adventitia Reserved and Anatomical Implant Technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Surveillance and Image-Guided Biopsy of the Esophagus Using an OFDI Capsule
Status: ACTIVE_NOT_RECRUITING
Conditions: Barrett's Esophagus
Interventions: DEVICE: OFDI Capsule Marking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients
Status: WITHDRAWN
Conditions: Respiratory Distress Syndrome, Adult|Ventilation Perfusion Mismatch|Pulmonary Edema|Covid19
Interventions: DEVICE: Extravascular Lung Water Index|DEVICE: Pulmonary Vascular Permeability Index
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Training Protocol 'Drop it'. The Impact of a Training Protocol Focused on Coping With Negative Repetitive Thinking on Cognitive and Behavioural Functioning of People Suffering From GAD or Minor or Moderate Depressive Disorder or Depressive Disorder in Remission
Status: COMPLETED
Conditions: Repetitive Negative Thinking|General Anxiety Disorder|Depressive Disorder|Depression|Anxiety Disorders|Worrying|Rumination
Interventions: BEHAVIORAL: Drop It training session|BEHAVIORAL: treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Utidelone in HER2-negative Inoperable Locally Advanced or Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasms|Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: utidelone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Provider and Peer Support Intervention to Improve ART Adherence Among Kenyan Men Who Have Sex With Men
Status: COMPLETED
Conditions: Medication Adherence
Interventions: BEHAVIORAL: Shikamana Intervention|BEHAVIORAL: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Test to Determine the Usefulness and Safety of a Cream Used on Babies With Dry Itchy Skin
Status: COMPLETED
Conditions: Eczema
Interventions: DEVICE: EpiCeram® Skin Barrier Emulsion|DRUG: Colloidal Oatmeal Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Adaptive Radiotherapy for Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Intensity modulated radiation therapy (IMRT) with conventional planning target volume (PTV) margin and without online adaptive radiotherapy|DRUG: Chemotherapy|RADIATION: Intensity modulated radiation therapy (IMRT) with smaller planning target volume (PTV) margin and online adaptive radiotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bio-enhanced Curcumin as an Add-On Treatment in Mild to Moderate Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: Bio-enhanced Curcumin Soft Gelatin Capsule|DRUG: 5-Aminosalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PROLIFIC ChemoprophylaxisTrial (COVID-19)
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine - Daily dosing|DRUG: Hydroxychloroquine - Weekly Dosing|OTHER: Matched Placebo Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Feasibility Testing an Exercise Program to Improve Cognition for T2DM Patients
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: BEHAVIORAL: Supervised walking on a treadmill|BEHAVIORAL: Supervised stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of The Ten-Session Dual-tDCS On Lower-Limb Performance in Sub- Acute Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke, Ischemic
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of MGCD265 in Patients With Non-Small Cell Lung Cancer With Activating Genetic Alterations in MET
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: MGCD265
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep and Pain in Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease|Sleep Disturbance|Pain
Interventions: BEHAVIORAL: Behavioral symptom management|OTHER: Sickle cell disease management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 308nm Excimer Laser for Treatment of Fingernail Psoriasis
Status: COMPLETED
Conditions: Nail Psoriasis
Interventions: DEVICE: 308 nm excimer laser|DEVICE: Sham laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standard Antiretroviral v. Multi-class Therapy in Acutely HIV-1 Infected Antiretroviral-Naïve Subjects (ADARC 2007-01)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: darunavir 800 mg|DRUG: FTC 200 mg/TDF 300mg|DRUG: Maraviroc|DRUG: Raltegravir|DRUG: Ritonavir 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning in Aneurysmal SAH
Status: RECRUITING
Conditions: Subarachnoid Hemorrhage, Aneurysmal|Delayed Cerebral Ischemia
Interventions: DEVICE: Remote Ischemic Conditioning with Automatic Tourniquet Device|DEVICE: Sham Remote Ischemic Conditioning with Automatic Tourniquet Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fidgety Movements of Preterm Neonates Included in COSGOD III
Status: RECRUITING
Conditions: Preterm|General Movements|Fidgety Movements|Near Infrared Spectroscopy|Neurological Outcome
Interventions: PROCEDURE: standard care plus cerebral oxygen saturation monitoring with a dedicated treatment guideline
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Duvelisib and Venetoclax in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Indolent or Aggressive Non-Hodgkin Lymphoma, Who Have Not Previously Received a Bcl-2 or PI3K Inhibitor
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|Non-Hodgkin Lymphoma
Interventions: DRUG: Duvelisib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Finding Safety and Efficacy Trial of Org50081 (Esmirtazapine) in the Treatment of Vasomotor Symptoms (46101/P06459/MK-8265-012)
Status: COMPLETED
Conditions: Menopause|Vasomotor Symptoms
Interventions: DRUG: esmirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: CONCERTA® (Methylphenidate Hydrochloride) as add-on Therapy in the Treatment of Adult Major Depressive Disorder.
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: DragONE Study: Acquisition and Maintenance of Paediatric Asthma Control: Usual Care vs Innovative Devices
Status: COMPLETED
Conditions: Asthma
Interventions: DEVICE: DragONE|DEVICE: SmartOne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
Status: RECRUITING
Conditions: Binge-Eating Disorder
Interventions: DRUG: Solriamfetol 150 mg|DRUG: Solriamfetol 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Digital Supported Compression Bandaging in Patients With Chronic Edema in the Lower Limbs
Status: NOT_YET_RECRUITING
Conditions: Compression; Vein|Venous Insufficiency|Lymphedema of Leg|Digital Technology
Interventions: OTHER: CIMON|OTHER: Sens Motion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Efficacy and Safety of CBL-514 in Participants With Dercum's Disease Lipomas
Status: COMPLETED
Conditions: Dercum's Disease
Interventions: DRUG: 10 mg CBL-514 per injection|DRUG: 15 mg CBL-514 per injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetics of Budesonide Delivered by PT027 Compared With Pulmicort Flexhaler (ELBRUS)
Status: COMPLETED
Conditions: Relative Bioavailability
Interventions: DRUG: BDA MDI 160/180 mcg|DRUG: Pulmicort Flexhaler 180 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Collection of Additional Biological Samples From Potentially COVID-19 Patients for Monitoring of Biological Parameters Carried Out as Part of the Routine
Status: NOT_YET_RECRUITING
Conditions: SARS CoV 2 Infection
Interventions: DIAGNOSTIC_TEST: RIPH2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Bone Grafting at the Time of Bone-Patellar Tendon-Bone ACL Reconstruction Reduce the Incidence of Post-operative Anterior Knee Pain: A Randomized Controlled Clinical Study
Status: UNKNOWN
Conditions: ACL Injury
Interventions: PROCEDURE: Autologous bone grafting|PROCEDURE: Absence of autologous bone grafting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Improvement of the Health-related Quality of Life of Patients With Fibromyalgia Using Multidisciplinary Treatment
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Interdisciplinary treatment|BEHAVIORAL: Interdisciplinary treatment of fibromyalgia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apremilast Treatment for Pruritus and Quality of Life in Scalp Psoriasis
Status: UNKNOWN
Conditions: Psoriasis of Scalp|Psoriasis Vulgaris
Interventions: DRUG: Apremilast 30mg|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Accu-Chek® CONNECT at School (CATS) Pediatric Study
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Accu-Chek® CONNECT DMS|DEVICE: DMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Premarket, Prospective, Randomized, Single-Blind Study to Compare the Veriset™ Hemostatic Patch to TachoSil® as an Adjunct to Hemostasis in Subjects Undergoing Cardiovascular Surgery
Status: COMPLETED
Conditions: Cardiac Surgical Procedures|Hemorrhage
Interventions: DEVICE: Veriset Hemostatic Patch|DEVICE: TachoSil®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Reducing Risk of Type 2 Diabetes: Hydroxychloroquine Use in Pre-Diabetes
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DRUG: hydroxychloroquine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transdermal Nitroglycerin and Nifedipine in Preterm Labor
Status: COMPLETED
Conditions: Managing Preterm Labor
Interventions: DRUG: Transdermal nitroglycerin|DRUG: nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vorapaxar in Patients With Prior Myocardial Infarction Treated With Prasugrel and Ticagrelor
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Prasugrel|DRUG: Vorapaxar|DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SURGERY VS BOTULINUM TOXIN ON QUALITY OF LIFE IN STROKE PATIENTS: RANDOMIZED TRIAL
Status: RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: spastic hand sugery|DRUG: Botulinum Toxin A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reproducibility of RNFL Circle Scans With ART-Function of Heidelberg Spectralis SD-OCT Software Version 5.3
Status: UNKNOWN
Conditions: Glaucoma Patients and Healthy Controls
Interventions: DEVICE: Spectralis® SD-OCT, Heidelberg Engineering GmbH, H
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Phase 1 Dose Escalation of ArtemiCoffee
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer
Interventions: DRUG: Artemisia annua 450mg|DRUG: Artemisia annua 900mg|DRUG: Artemisia annua 1350mg|DRUG: Artemisia annua 1800mg|DRUG: Artemisia annua - recommended phase II dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise on PETCO2 Response in Coronary Artery Disease Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Exercise Addiction|Complication, Cardio-respiratory
Interventions: OTHER: aerobic exercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study of Single and Multiple Doses of AG-181 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: AG-181|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Pletaal SR Capsule (Cilostazol) in Subjects With Peripheral Arterial Disease Symptom Due to Chronic Occlusive Arterial Disease
Status: COMPLETED
Conditions: Chronic Occlusive Arterial Disease
Interventions: DRUG: Pletaal SR capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Two Regenerative Scaffolds
Status: COMPLETED
Conditions: Pulp Necroses
Interventions: PROCEDURE: Endodontic regeneration using concentrated growth factor compared with Platelet rich fibrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating the Use of Simultaneous HBV, HCV, and HIV Rapid Tests
Status: COMPLETED
Conditions: HIV|Hepatitis B|Hepatitis C|Carcinoma, Hepatocellular|AIDS
Interventions: OTHER: ELISA|OTHER: Rapid Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron in Sexually Active Men With OAB Symptoms
Status: COMPLETED
Conditions: Urinary Bladder, Overactive|Sexual Behavior|Sexual Activity|Behavior Therapy|Sexual Function Disturbances
Interventions: BEHAVIORAL: Behavior therapy alone|DRUG: Mirabegron 50 MG Extended Release Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Behavioral Science-Enhanced PHysician-led Remote Group Exercise InTervention for Women With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease|Physical Inactivity|Sedentary Behavior
Interventions: BEHAVIORAL: Physician-Led Remote Exercise Program Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Immediate Effects of Two Ankle Mobilization Techniques in the Amplitude of Dorsiflexion and Dynamic Valgus Knee
Status: COMPLETED
Conditions: Ankle Joint Contracture|Knee Injuries and Disorders
Interventions: OTHER: Mobilization with movement|OTHER: Self mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: 3% hydrogen peroxide solution with HydraGlyde® Moisture Matrix|DEVICE: Habitual Multi-Purpose Contact Lens Solution|DEVICE: Habitual Contact Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluating Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
Status: TERMINATED
Conditions: Opioid Pain Medication
Interventions: DRUG: Tranexamic acid|DRUG: Aminocaproic acid|DRUG: Recombinant Human Thrombin|DRUG: Lidocaine Hydrochloride with Epinephrine|DRUG: Bupivacaine Hydrochloride with Epinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib/Dexamethasone Therapy in Patients With Relapsed and/or Refractory Cutaneous T-cell Lymphoma
Status: COMPLETED
Conditions: Relapsed and/or Refractory Cutaneous T-cell Lymphoma
Interventions: DRUG: bortezomib/dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Postoperative Wound Infections by Antiseptica?
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: DRUG: Polihexanide; Serasept|DRUG: NaCl; saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Light Dose Ranging Study of Photodynamic Therapy (PDT) With Levulan + Blue Light Versus Vehicle + Blue Light in Severe Facial Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: aminolevulinic acid HCL (ALA)|OTHER: Vehicle (VEH)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol and Huntington Disease
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DIETARY_SUPPLEMENT: Resveratrol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Meleis Theory on Postpartum Depression, Breastfeeding, and Maternal Self-Efficacy in Women Experiencing Preterm Birth
Status: RECRUITING
Conditions: Premature Birth|Theory, Double Bind|Postpartum Depression|Breast Feeding|Self Efficacy
Interventions: OTHER: Postpartum Maternal Care and Premature Infant Care Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxytocin and Stress Response in Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Doxorubicin, and Prednisone in Treating Patients With Advanced Prostate Cancer That Has Not Responded to Hormone Therapy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Vitamin D Supplementation on Pregnant Women With the Risk of GDM
Status: NOT_YET_RECRUITING
Conditions: Gestational Diabetes Mellitus
Interventions: DRUG: Placebo supplementation|DRUG: Vitamin D supplementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effectiveness of Ultrapulse for the Treatment of Androgenic Alopecia Among Malaysian: A Quasi-experimental Study
Status: NOT_YET_RECRUITING
Conditions: Androgenic Alopecia|Alopecia
Interventions: DEVICE: Er:YAG laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Randomized, Double-blind, Placebo Controlled Trial Comparing the Efficacy of Gemcitabine, Cisplatin and Sorafenib to Gemcitabine, Cisplatin and Placebo in First-Line Treatment of Patients With Stage IIIb With Effusion and Stage IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)|DRUG: Placebo|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Pilot Study of Dirithromycin of (Abdi İbrahim İlaç San.Ve.Tic.A.Ş,Turkey) in Healthy Subjects Under Fasting Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: DIRITHROMYCIN 500 MG ENTERIC COATED TABLET|DRUG: DYNABAC 250 MG ENTERIC COATED TABLET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Diagnosis of Pseudoprogression Using 11C-Methionine PET-MRI After Concomitant Radiochemotherapy Treatment for Glioblastoma.
Status: RECRUITING
Conditions: Glioblastoma
Interventions: OTHER: 11C-Methionine PET-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Bracket Failure With a Novel Etchant Paste. A Randomized Clinical Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthodontic Appliance Complication
Interventions: OTHER: Enamel conditioning with a novel etchant paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Informative Letters on the Prescription and Receipt of Seroquel
Status: COMPLETED
Conditions: Economics|Fraud|Delivery of Health Care|Health Expenditures|Centers for Medicare and Medicaid Services (U.S.)
Interventions: OTHER: Placebo letter|OTHER: Initial Informative letter|OTHER: Followup Informative Letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase 1 Drug Interaction Study of Apixaban and Atenolol in Healthy Subjects
Status: COMPLETED
Conditions: N/A - Healthy Subjects
Interventions: DRUG: Apixaban|DRUG: Atenolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beta 3 Agonist Treatment in Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: DRUG: Mirabegron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT