pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Rosiglitazone Versus Placebo on Cardiovascular Performance and Myocardial Triglyceride
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: rosiglitazone|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure.
Status: COMPLETED
Conditions: Covid19|Acute Hypoxemic Respiratory Failure
Interventions: PROCEDURE: Conventional oxygen therapy|PROCEDURE: High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Findings and Side-effects of Flexible Endoscopic Evaluation of Swallowing - the FEES-Registry
Status: COMPLETED
Conditions: Neurogenic Dysphagia|Flexible Endoscopic Evaluation of Swallowing
Interventions: PROCEDURE: Flexible Endoscopic Evaluation of Swallowing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating The Safety And Tolerability Of Administration Of Single Oral Doses Of SAM-760 To Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SAM-760|DRUG: Placebo of SAM-760|DRUG: ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Islet-Kidney Transplantation in Patients of Type 1 Diabetes With End-stage Renal Disease
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus|End-stage Renal Disease
Interventions: PROCEDURE: simultaneous islet-kidney transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy of Pharmacogenetic Information Obtained With NEUROPHARMAGEN in Treatment of MDD Patients
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: GENETIC: NEUROPHARMAGEN-Guided Treatment|DRUG: Treatment As Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methodological Evaluation of Gingival Crevicular Fluid Volume and Elastase Level
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: OTHER: Gingival crevicular fluid collection with filter paper
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Behavioral Health Evaluation and Intervention Program for Patients Undergoing Craniotomy
Status: NOT_YET_RECRUITING
Conditions: Brain Tumor
Interventions: BEHAVIORAL: Counseling Sessions|BEHAVIORAL: Quality of Life Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Electrical Resynchronization and Acute Hemodynamic Effects of Direct His Bundle Pacing Compared to Biventricular Pacing
Status: COMPLETED
Conditions: Cardiac Pacing, Artificial|Cardiac Resynchronization Therapy|Direct His Bundle Pacing
Interventions: DEVICE: Pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of FB825 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: FB825|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness of MR Enterography
Status: COMPLETED
Conditions: Crohns Disease
Interventions: PROCEDURE: MRE (magnetic resonance enterography)|PROCEDURE: The Ultrasound scan, (UEI) Ultrasound Elastography Imaging with ARFI (acoustic radiation force impulse)|BEHAVIORAL: Study Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oxymetazoline Hydrochloride in Combination With Nasal Glucocorticosteroid for Perennial Allergic and Non-allergic Rhinitis in Subjects With Persistent Nasal Congestion
Status: TERMINATED
Conditions: Chronic Rhinitis
Interventions: DRUG: Oxymetazoline Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health
Status: RECRUITING
Conditions: Obesity|Insulin Resistance
Interventions: OTHER: Metabolically abnormal obese - Mediterranean diet|OTHER: Metabolically abnormal obese - Low carbohydrate ketogenic diet|OTHER: Metabolically abnormal obese - Plant-based, very-low-fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Quality Improvement Strategies to Increase Human Papillomavirus (HPV) Vaccination
Status: COMPLETED
Conditions: Human Papillomavirus Infection
Interventions: OTHER: Assessment Feedback Incentives and eXchange|OTHER: Physician-to-physician engagement|OTHER: Active Intervention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Nicotinamide (NAM) and Pyridoxine (Vitamin B6) on Muscle Regeneration ("Satellite-01 Study").
Status: COMPLETED
Conditions: Muscle Injury
Interventions: DIETARY_SUPPLEMENT: NAM/B6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Patients With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: XL309 (ISM3091)|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab and Dabrafenib in the 1st Line Tx of Unresectable Stage III/IV Melanoma
Status: TERMINATED
Conditions: Stage III or IV Melanoma
Interventions: DRUG: ipilimumab and dabrafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Supratentorial Brain Tumors
Status: RECRUITING
Conditions: Brain Tumor, Pediatric
Interventions: DRUG: 5-Aminolevulinic Acid Hydrochloride, Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Balancing Lupus Experiences With Stress Strategies
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BEHAVIORAL: Arthritis Self Management Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Rate Response With CLS Versus Accelerometer ICD Settings in Heart Failure Patients With BIOTRONIK CRT-Ds
Status: COMPLETED
Conditions: Heart Failure|ICD|Chronotropic Incompetence
Interventions: DEVICE: CLS Mode on Biotronik CRT-D|DEVICE: Accelerometer Mode on Biotronik CRT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Efficacy and Safety of Bortezomib in Patients With Severe Autoimmune Encephalitis
Status: RECRUITING
Conditions: Autoimmune Encephalitis
Interventions: DRUG: Bortezomib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: OTHER: NCEP Step 1 diet plus Almonds|OTHER: No Almonds
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Evogliptin in Type 2 Diabetes Mellitus (EVOLUTION: EVOgLiptina no Diabetes Mellitus TIpO 2)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Evogliptin|DRUG: Sitagliptin|DRUG: Placebo Evogliptin|DRUG: Placebo Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sonodynamic Therapy Manipulates Atherosclerosis Regression Trial on Patients With PAD and Claudication
Status: COMPLETED
Conditions: Peripheral Arterial Disease|Atherosclerosis|Cardiovascular Diseases
Interventions: COMBINATION_PRODUCT: OMC and pseudo-SDT|COMBINATION_PRODUCT: OMC and SDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Collagen Plug for Alveolar Socket Sealing With Simultaneous Implant Placement in Maxillary Esthetic Zone
Status: UNKNOWN
Conditions: Badly Decayed Upper Anterior Teeth
Interventions: PROCEDURE: free gingival graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cemiplimab in AlloSCT/SOT Recipients With CSCC
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Squamous Cell Carcinoma|Advanced Cancer
Interventions: DRUG: Cemiplimab|DRUG: Everolimus|DRUG: Sirolimus|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: earlY Upper Limb Rehabilitation WIth EEG-Neurofeedback After Stroke
Status: RECRUITING
Conditions: Stroke|Stroke Hemorrhagic|Stroke, Ischemic|Stroke Rehabilitation|Brain Infarction
Interventions: OTHER: electroencephalographic neurofeedback|OTHER: SHAM electroencephalographic neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Non-squamous Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: TH-302 combination with pemetrexed|DRUG: Matched placebo in combination with pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Cream SNG100 for Treatment in Moderate Atopic Dermatitis Subjects.
Status: UNKNOWN
Conditions: Atopic Dermatitis
Interventions: DRUG: Hydrocortisone Acetate 1% Cream|DRUG: Mometasone Furoate|DRUG: SNG100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Versus Glipizide in Participants With Type 2 Diabetes Mellitus and Chronic Renal Insufficiency (MK-0431-063 AM1)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Renal Insufficiency, Chronic
Interventions: DRUG: Sitagliptin|DRUG: Glipizide|DRUG: Placebo for Sitagliptin|DRUG: Placebo for Glipizide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of "MaRiTensi" in Increasing Self-Care and Blood Pressure Control: Randomized Controlled Trial
Status: COMPLETED
Conditions: Primary Hypertension
Interventions: BEHAVIORAL: MaRiTensi App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Restoration of Beta Cell Function and Cardiovascular Parameters in Relation to Adipoinsular and Enteroinsular Axes After Gastric Bypass Surgery
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Bariatric Surgery Candidate
Interventions: PROCEDURE: gastric bypass surgery|PROCEDURE: abdominal surgery|BEHAVIORAL: very low caloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pressure Supporting Ventilation and EEG-guided Emergence for Free of Unwanted Complications
Status: RECRUITING
Conditions: Thyroid Surgery
Interventions: PROCEDURE: PSV|PROCEDURE: Intermittent Manual Assistance|PROCEDURE: EEG-Guidance|PROCEDURE: Obey Command|PROCEDURE: Spontaneous Respiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Oral Sprays on Salivary pH
Status: COMPLETED
Conditions: Oral Health
Interventions: OTHER: No intervention (negative control)|OTHER: Water (positive control)|DRUG: Dental foam "Biorepair PERIBIOMA"|DRUG: Dental foam "WATER:DENT"|DRUG: Dental spray "BUCCOTHERM"
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Different Regimens in Influenza Postexposure Chemoprophylaxis in Children
Status: UNKNOWN
Conditions: Influenza|Exposure|Prevention
Interventions: DRUG: Oseltamivir 3 days|DRUG: Oseltamivir 7 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: IV Acetaminophen as an Adjunct Analgesic in Cardiac Surgery
Status: COMPLETED
Conditions: Acute Pain|Hyperalgesia
Interventions: DRUG: IV acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Two Multifocal Intraocular Lens With Different Add Power
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: +2.75 diopters multifocal intraocular lens|DEVICE: +3.25 diopters multifocal intraocular lens
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of NEP Inhibition on Vascular Leak and Inflammation (NEPi-INFLAMMATION)
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome
Interventions: DRUG: Racecadotril 100 milligram (MG) Oral Capsule|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Resistance Exercise Effects on Fear Avoidance and Physical Function in Obese Older Adults With Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain|Obesity
Interventions: OTHER: normal medical care and follow up|OTHER: Isolated Lumbar Resistance Exercise Program|OTHER: Total Body Resistance Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Dose-finding IMU-838 for Ulcerative Colitis
Status: TERMINATED
Conditions: Ulcerative Colitis
Interventions: DRUG: IMU-838|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Upper Extremity Robotic Rehabilitation in Children With Spastic Hemiparetic Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Hemiplegic Cerebral Palsy|Upper Extremity Paresis|Robotic Rehabilitation
Interventions: OTHER: Conventional physiotherapy|OTHER: Robotic Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aflibercept in Patients With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration|Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: Aflibercept (CinnaGen Co, Iran)|BIOLOGICAL: Aflibercept (Regeneron, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Perioperative Aminophylline to Improve Early Kidney Function After a Kidney Transplant
Status: COMPLETED
Conditions: Function of Renal Transplant
Interventions: DRUG: Aminophylline|OTHER: Theophylline drug levels|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of rhGM-CSF on the Healing of Venous Leg Ulcers
Status: ACTIVE_NOT_RECRUITING
Conditions: Venous Leg Ulcer
Interventions: DRUG: rhGM-CSF + hydrogel|DRUG: Placebo hydrogel|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Vesalio NeVa Stent Retriever Study for Treatment of Large Vessel Occlusion Strokes: CLEAR Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DEVICE: NeVa Stent Retrievers
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Equivalence of Ovine Enoxaparin to Lovenox®
Status: COMPLETED
Conditions: Enoxaparin
Interventions: DRUG: Ovine Enoxaparin|DRUG: Enoxaparin Prefilled Syringe [Lovenox]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
Status: COMPLETED
Conditions: Gingivitis|Dental Plaque
Interventions: DRUG: Corsodyl Original Dentifrice|DRUG: Colgate Cavity Protection Dentifrice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Estrogen Receptor Expression in Breast Cancer - Assessed With Positron Emission Mammography
Status: WITHDRAWN
Conditions: Breast Neoplasm
Interventions: DIAGNOSTIC_TEST: F-18 FES|DIAGNOSTIC_TEST: F-18 FDG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Inflation-deflation Method for Nasal Intubation in Pediatric Patients
Status: UNKNOWN
Conditions: Nasal Intubation
Interventions: PROCEDURE: cuff deflation-inflation -deflation method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thymosin Plus PEG-Interferon in Hepatitis C Patients With Cirrhosis Who Did Not Respond to Interferon or Interferon Plus Ribavirin
Status: COMPLETED
Conditions: Hepatitis C|Hepatitis C, Chronic
Interventions: DRUG: thymalfasin (thymosin alpha 1)|DRUG: PEGinterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Oral Ciprofloxacin in the Treatment of Adults With Uncomplicated Infections of the Skin and the Supportive Layers Beneath the Skin
Status: COMPLETED
Conditions: Skin Diseases, Infectious
Interventions: DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Immune Responses to Influenza Vaccine In Adults of Different Ages (SLVP015 2007-2017)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent, inactivated influenza vaccine (TIV)|BIOLOGICAL: Quadrivalent, inactivated influenza vaccine (IIV4)|BIOLOGICAL: High-Dose Trivalent, inactivated influenza vaccine (TIV High-Dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective Trial of Autologous Platelet Rich Plasma in Aortic Surgery
Status: COMPLETED
Conditions: C.Surgical Procedure; Cardiac
Interventions: DEVICE: Autologous Platelet-Rich Plasma Harvest Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Oral Fosamprenavir-Sodium Alginate for LPR
Status: NOT_YET_RECRUITING
Conditions: Laryngopharyngeal Reflux
Interventions: DRUG: Fosamprenavir Calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupoint Stimulation on Postoperative Delirium and Electroencephalogram
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Postoperative Delirium|Electroencephalogram
Interventions: OTHER: transcutaneous electrical acupoint stimulation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Accuracy of Topography Guided Automatic Marking of the Intraocular Lens (IOL) -Axis
Status: ACTIVE_NOT_RECRUITING
Conditions: Cataract Senile|Astigmatism
Interventions: PROCEDURE: Marking of the intended axis of IOL-Implantation manually with an ink and marking device on the surface of the eye
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer Female|Triple Negative Breast Cancer
Interventions: COMBINATION_PRODUCT: quercetin, EGCG, metformin , zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Letrozole and CC Alone in an IUI Program in Cases With Surgically Treated Minimal to Mild Endometriosis
Status: COMPLETED
Conditions: Endometriosis
Interventions: DRUG: Letrozole/IUI|DRUG: CC/IUI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs
Status: COMPLETED
Conditions: Cystic Fibrosis|Cystic Fibrosis Gastrointestinal Disease|Cystic Fibrosis of Pancreas
Interventions: DRUG: MS1819-SD
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DEXTENZA Compared to Topical Prednisolone in Patients Undergoing Bilateral LASIK Surgery
Status: UNKNOWN
Conditions: Refractive Surgery
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert|DRUG: Topical Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Verb Network Strengthening Treatment (VNeST) Via Telerehabilitation on Word Finding in Post-stroke Aphasia.
Status: RECRUITING
Conditions: Aphasia|Anomia|Stroke
Interventions: BEHAVIORAL: Verb Network Strenghtening Treatment (VNeST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A First Time in Man, Study to Assess the Safety of AZD8329 After Single Ascending Oral Doses
Status: COMPLETED
Conditions: Healthy Men
Interventions: DRUG: AZD8329|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Establishment and Application of an Artificial Intelligence Algorithm for Automatic Identification of Intraoperative Bleeding During Laparoscopic Pancreaticoduodenectomy
Status: RECRUITING
Conditions: Laparoscopic Pancreaticoduodenectomy
Interventions: OTHER: laparoscopic pancreaticoduodenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Choline and Cardiometabolic Health
Status: COMPLETED
Conditions: Cardiovascular Risk Factor
Interventions: DIETARY_SUPPLEMENT: Choline capsule|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52H in Healthy Volunteers
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: C52R1M Tab. and C52R2 Tab.|DRUG: AJU-C52H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Test the Effectiveness of MK0217 in Patients With Paget's Bone Disease (0217-206)(COMPLETED)
Status: COMPLETED
Conditions: Paget's Disease of Bone
Interventions: DRUG: alendronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: iPACK Block for Total Knee Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis|Knee Pain Chronic|Knee Disease
Interventions: DRUG: Ropivacaine 0.5% Injectable Solution 20mL|DRUG: 0,9% normal saline 20mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oculomotor Training and Chinese Characters Recognition in Children With Neuromuscular Disease
Status: COMPLETED
Conditions: Extraocular Muscle Disorder|Neuromuscular Diseases
Interventions: OTHER: gaze-directed oculomotor training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Pharmacokinetic Drug Interaction and Safety of Telmisartan/Amlodipine and Rosuvastatin
Status: COMPLETED
Conditions: Hypertension|Hyperlipidemia
Interventions: DRUG: Twynsta 80/5mg|DRUG: Crestor 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parent-Child Early Approaches to Raising Language Skills (PEARLS) Intervention
Status: COMPLETED
Conditions: Deafness, Bilateral
Interventions: BEHAVIORAL: Parent-Child Early Approaches to Raising Language Skills|OTHER: Standard Care Speech therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Outcomes With Multifocal Intraocular Lenses
Status: RECRUITING
Conditions: Cataract
Interventions: DEVICE: SN6AD1|DEVICE: SBL-3|DEVICE: LS-313 MF30|DEVICE: AT LISA tri 839 MP|DEVICE: ART|DEVICE: LS-313 MF30T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: peficitinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiorespiratory Fitness and Health Parameters in E-cigarrete Users: Impact of a Short Term Pause in Consumption
Status: NOT_YET_RECRUITING
Conditions: Electronic Nicotine Delivery Systems
Interventions: BEHAVIORAL: Pause
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Vitamin D and T-Regulatory Cells in Coronary Artery Disease
Status: TERMINATED
Conditions: Coronary Artery Disease|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D|OTHER: No medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Longitudinal Outpatient Treatment for Cannabis Use Disorder
Status: RECRUITING
Conditions: Cannabis Use Disorder
Interventions: DRUG: Cannabidiol - fsCBD|DRUG: Placebo|DRUG: Cannabidiol - bsCBD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cocoa Flavanol Supplementation in Raynaud's Phenomenon
Status: COMPLETED
Conditions: Primary Raynaud Phenomenon
Interventions: DIETARY_SUPPLEMENT: High Flavanol Cocoa extract|DIETARY_SUPPLEMENT: Alkalised cocoa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Frontal Sinus Surgery Draf III in Moderate to Severe Eosinophilic Chronic Rhinosinusitis With Polyps
Status: RECRUITING
Conditions: Endoscopic Frontal Sinus Surgery|Chronic Rhinosinusitis With Nasal Polyps|Draf III|Draf I or IIa
Interventions: PROCEDURE: Endoscopic frontal sinus surgery grade 6(Draf III).|PROCEDURE: Endoscopic frontal sinus surgery grade 1-3(Draf I or IIa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Cyclophosphamide or CNI in the Prevention of Acute Graft-versus-host Disease After gDLI
Status: NOT_YET_RECRUITING
Conditions: Acute Graft-versus-host Disease
Interventions: DRUG: PDCy|DRUG: Non Cy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N-Acetylcysteine to Prevent Radiocontrast Nephropathy in Emergency Department Patients
Status: COMPLETED
Conditions: Radiocontrast Nephropathy
Interventions: DRUG: N-Acetylcysteine (NAC)|DRUG: 0.9% Sodium-chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Exercise Versus Exercise and Instrument-Assisted Soft Tissue Mobilization for Plantar Fasciopathy Treatment
Status: COMPLETED
Conditions: Plantar Fascitis
Interventions: OTHER: Instrumental-assisted soft tissue mobilization (IASTM)|OTHER: High-Load Strength Training|OTHER: Plantar Flexor and Gastrocnemius Stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Electrical Brain Stimulation for Cognitive Impairment in Schizophrenia: a tDCS-fMRI Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia|Cognitive Impairment
Interventions: DEVICE: transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study)
Status: RECRUITING
Conditions: Ovarian Neoplasms|Endometrial Neoplasms|Uterine Cervical Neoplasms|Vulvar Cancer|Vagina Neoplasm|Clear Cell Carcinoma
Interventions: DRUG: Dostarlimab|DRUG: Bevacizumab|DRUG: Doxorubicin|DRUG: Gemcitabine|DRUG: Paclitaxel|DRUG: Pegylated liposomal doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dismantling Mindfulness: Contributions of Attention vs. Acceptance
Status: COMPLETED
Conditions: Mild-moderate Unipolar Depression; Persistent Negative Affect
Interventions: BEHAVIORAL: Mindfulness-Based Cognitive Therapy|BEHAVIORAL: Focused Attention (FA)|BEHAVIORAL: Open- Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Xalatan Compared To Usual Care In Patients With Open Angle Glaucoma Or Ocular Hypertension.
Status: COMPLETED
Conditions: Ocular Hypertension|Glaucoma, Open-Angle
Interventions: DRUG: latanoprost 0.005% (Xalatan)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy
Status: COMPLETED
Conditions: Non-Proliferative Diabetic Retinopathy
Interventions: DRUG: 1.0mg Luminate®|DRUG: 2.0mg Luminate®|DRUG: 3.0mg Luminate®|OTHER: Balanced Salt Solution for intravitreal injection in 0.10cc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Antibiotic Regimen in Periodontitis Treatment
Status: COMPLETED
Conditions: Amoxicillin|Metronidazole|Ofloxacin|Periodontitis|Root Planing
Interventions: DRUG: Ofloxacin|DRUG: Amoxicillin|DRUG: Metronidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death
Status: TERMINATED
Conditions: Coronary Heart Disease|Congestive Heart Failure|Ventricular Dysfunction|Low Cardiac Output|Sudden Cardiac Death
Interventions: DRUG: Optimized medical therapy|DEVICE: Implantable Cardioverter Defibrillator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cold Application Effects on Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: ENROLLING_BY_INVITATION
Conditions: Laparoscopic Cholecystectomy|Postoperative Nausea and Vomiting
Interventions: OTHER: Cold Application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Combination of Sorafenib and Radiation for Brain Metastases and Primary Brain Tumors
Status: COMPLETED
Conditions: Brain Metastases|Primary Brain Tumors
Interventions: DRUG: Sorafenib|DRUG: Temozolomide|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed or Refractory Natural Killer/T Cell Lymphoma
Status: UNKNOWN
Conditions: Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type
Interventions: DRUG: Pembrolizumab (PD-1 Blocking Antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial Disease
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Fuzzy Wale Compression Stockinet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis
Status: COMPLETED
Conditions: Glomerulosclerosis, Focal Segmental
Interventions: DRUG: VX-147
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RL Versus Glucose Saline in Cancer Patient Undergoing Major Surgeries and Its Impact on Electrolytes, GLC & pH
Status: ACTIVE_NOT_RECRUITING
Conditions: Fluid and Electrolyte Imbalance
Interventions: OTHER: Lactated ringer and dextrose 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of SAF312 as an Eye Drop for Treatment of Eye Pain Following Photorefractive Keratectomy (PRK) Surgery
Status: COMPLETED
Conditions: Postoperative Ocular Pain After PRK Surgery
Interventions: DRUG: SAF312|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Haemophilus Influenza Type b Vaccine When Administered to Korean Children
Status: COMPLETED
Conditions: Haemophilus Influenzae Type B Infection
Interventions: BIOLOGICAL: Haemophilus influenza type b conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma|Stage IVB Cervical Cancer
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Cisplatin|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: simvastatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HKI-272 for HER2-Positive Breast Cancer and Brain Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: HKI-272|PROCEDURE: Surgical Resection|DRUG: Capecitabine|DRUG: HKI-272|DRUG: Ado-Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvements in Pneumonia Status After Oral Care Intervention in Taiwan
Status: COMPLETED
Conditions: Pneumonia
Interventions: OTHER: Routine oral cleaning and professional oral care group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The RATIO: Registry of Infections and Lymphoma in Patients Treated With TNF-a Antagonists
Status: UNKNOWN
Conditions: Rheumatoid Arthritis|Crohn's Disease|Ankylosing Spondylitis|Psoriasis
Interventions: DRUG: TNF-alpha antagonists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Improving ACL Reconstruction Outcomes: CBPT
Status: COMPLETED
Conditions: ACL Injury|ACL - Anterior Cruciate Ligament Rupture|ACL Sprain|ACL Tear
Interventions: BEHAVIORAL: CBPT-ACLR|OTHER: Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extravascular Lung Water Monitoring by Combined Ultrasound and Bioimpedance as a Guide for Treatment in Hemodialysis Patients
Status: COMPLETED
Conditions: Patients on Hemodialysis for More Than 3 Months
Interventions: OTHER: Active arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Percutaneous Tracheostomy Compared to Bronchoscopy Guided Percutaneous Tracheostomy
Status: COMPLETED
Conditions: Tracheostomy Complications
Interventions: DEVICE: Ultrasound guided percutaneous tracheostomy|DEVICE: Bronchoscopy guided percutaneous tracheostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hydrogen-Oxygen Generator With Nebulizer in the Improvement of Symptoms in Patients Infected With COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: DEVICE: oxyhydrogen|DEVICE: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addressing Sleep Apnea Post-Stroke/TIA
Status: ACTIVE_NOT_RECRUITING
Conditions: Ischemic Stroke|Transient Ischemic Attack (TIA)|Obstructive Sleep Apnea
Interventions: OTHER: ASAP Intervention Quality Improvement Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A PD Study of Oral eFT508 in Subjects With Advanced TNBC and HCC
Status: TERMINATED
Conditions: Triple Negative Breast Cancer|Hepatocellular Carcinoma
Interventions: DRUG: eFT508
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CHESS Caregivers Study: Web-based Support for Informal Caregivers in Cancer
Status: COMPLETED
Conditions: Breast Cancer|Prostate Cancer
Interventions: BEHAVIORAL: Comprehensive Health Enhancement Support System|BEHAVIORAL: computer with internet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Passive Body Heating, Sleep and Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: OTHER: Polysomnography|OTHER: Teperature measure|OTHER: Fibromyalgia Impact questionary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Vitamin D3 and Calcium Supplementation in Attenuating T2DM Severity
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DIETARY_SUPPLEMENT: vitamin D3 and calcium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2
Status: COMPLETED
Conditions: Venous Leg Ulcers
Interventions: BIOLOGICAL: HP802-247|BIOLOGICAL: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Self Management for Hypertension & Prehypertension Using an Internet Enabled, Automated Self Management Program
Status: COMPLETED
Conditions: Blood Pressure
Interventions: OTHER: Internet-enabled automated self-management program|OTHER: BP cuff at workplace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: GSK2251052 in the Treatment of Complicated Intra-abdominal Infections
Status: TERMINATED
Conditions: Infections, Intestinal
Interventions: DRUG: Drug: GSK2251052|DRUG: Meropenem|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Daewon-ES(B) & Megace in Healthy Male Volunteers Under Fed Condition
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Megace 800mg/20ml|DRUG: DW-ES(B) 625mg/5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of BGS649 in Obese, Hypogonadotropic Hypogonadal Men
Status: TERMINATED
Conditions: Obese Hypogonadotropic Hypogonadism
Interventions: DRUG: Investigational new drug company code: BGS649|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: S(+)-ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Arch Support Effects on Balance and Gait in Older Adults With Mild Cognitive Impairment
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DEVICE: arch support insoles (FootDisc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial
Status: RECRUITING
Conditions: Intracranial Aneurysm|Subarachnoid Hemorrhage
Interventions: DRUG: Deferoxamine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Accuracy and Precision of a New Arterial Blood Gas Analysis System Blood in Comparison With the Reference Standard
Status: TERMINATED
Conditions: Hypoxia|Hypercapnia|Anaemia
Interventions: DEVICE: conventional ABG analyser|DEVICE: Proxima 3®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER