pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Pharmaceutical Care in the Reduction of Readmission Rates in Diabetes Melitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Structured pharmaceutical care|BEHAVIORAL: Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of 5-Aminolevulinic Acid on Glucose Metabolism
Status: COMPLETED
Conditions: Type 2 Diabetes on Medication
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: 5-aminolevulinic acid phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bioequivalence of Two Levothyroxine Tablet Formulations in Healthy Indian Volunteers
Status: COMPLETED
Conditions: Hypothyroidism
Interventions: DRUG: Levothyroxine|DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Cavosonstat Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: OTHER: placebo|DRUG: Cavosonstat 5 mg|DRUG: Cavosonstat 10 mg|DRUG: Cavosonstat 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: IRAPs (Secreted Insulin Regulated AminoPeptidase): a New Insulin Sensitivity Biomarker
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: OTHER: It is a hyperinsulinemic-euglycemic clamp.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Positive Psychological Deconditioning of Pediatric Patients With Dental Anxiety Through Artificial Intelligence
Status: COMPLETED
Conditions: Dental Anxiety|Dental Phobia
Interventions: OTHER: AI-video|OTHER: Verbal instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving the Quality of Care for Atrial Fibrillation by Promoting Patient-Centered Decision Making
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: BEHAVIORAL: Decision Aid for Atrial Fibrillation|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: MNGIE Allogeneic Hematopoietic Stem Cell Transplant Safety Study
Status: WITHDRAWN
Conditions: Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
Interventions: BIOLOGICAL: Hematopoietic Allogeneic Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS II)
Status: TERMINATED
Conditions: Lupus Erythematosus, Systemic
Interventions: DRUG: Atacicept 75 mg|DRUG: Atacicept 150 mg|DRUG: Atacicept 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Reserve With Caffeine Manipulation
Status: COMPLETED
Conditions: Caffeine|Placebo
Interventions: DIETARY_SUPPLEMENT: Caffeine|DIETARY_SUPPLEMENT: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking
Status: COMPLETED
Conditions: Bladder Cancer|Cervical Cancer|Esophageal Cancer|Gastric Cancer|Head and Neck Cancer|Kidney Cancer|Leukemia|Liver Cancer|Lung Cancer|Pancreatic Cancer|Tobacco Use Disorder
Interventions: BEHAVIORAL: smoking cessation intervention|DRUG: bupropion hydrochloride|GENETIC: gene expression analysis|GENETIC: polymerase chain reaction|OTHER: counseling intervention|OTHER: educational intervention|PROCEDURE: psychosocial assessment and care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ivabradine to Improve Endothelial Function in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Ivabradine|DRUG: Standard medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Glioma|Glioblastoma|Glioblastoma Multiforme|GBM|Brain Cancer
Interventions: DRUG: VAL-083 (Dianhydrogalactitol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
Status: TERMINATED
Conditions: Spasticity With Multiple Sclerosis
Interventions: DRUG: Nabiximols|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Autogenic and Reciprocal Inhibition Techniques With Conventional Therapy in Mechanical Neck Pain
Status: COMPLETED
Conditions: Mechanical Neck Pain
Interventions: OTHER: Autogenic Inhibition MET|OTHER: Reciprocal Inhibition MET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Beta Hydroxybutyrate Ester in Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: Beta Hydroxybutyrate Ester (KetoneAid KE4)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab in Combination With Androgen Suppression Therapy in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: BIOLOGICAL: ipilimumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Group B Streptococcus Vaccine in Pregnant Women Living With HIV and in Pregnant Women Who do Not Have HIV
Status: COMPLETED
Conditions: Group B Streptococcal Infection
Interventions: BIOLOGICAL: GBS-NN/NN2|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties
Status: NOT_YET_RECRUITING
Conditions: Total Knee Arthroplasty|Knee Osteoarthritis
Interventions: DEVICE: Attune knee implant|DEVICE: Triathlon knee implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Vagus Nerve Stimulation on Central Pain Sensitivity & Parasympathetic Function in Knee Osteoarthritis
Status: RECRUITING
Conditions: Knee Osteoarthritis|Central Pain Syndrome
Interventions: DEVICE: Transcutaneous vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Placental Derived Exosomes and Umbilical Cord Mesenchymal Stem Cells in Moderate to Severe Acute Respiratory Distress Syndrome (ARDS) Associated With the Novel Corona Virus Infection (COVID-19)
Status: RECRUITING
Conditions: COVID-19 Acute Respiratory Distress Syndrome|Respiratory Distress Syndrome
Interventions: DRUG: EV-Pure™ and WJ-Pure™|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can DFN-15 Terminate Migraine With Allodynia?
Status: COMPLETED
Conditions: Migraine With Aura|Migraine Without Aura|Allodynia
Interventions: DRUG: DFN-15|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of PEG-IFN-SA and Ribavirin to Treat Chronic Hepatitis C
Status: COMPLETED
Conditions: Chronic Hepatitis c
Interventions: DRUG: PEG-IFN-SA /RBV|DRUG: Pegasys /RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Safety Study of PEG-IFN in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIIB017 (PEGylated Interferon Beta-1a)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: adriamycin|DRUG: epirubicin|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protective Variable Ventilation for Open Abdominal Surgery
Status: COMPLETED
Conditions: Development of Pulmonary Dysfunction Following Open Abdominal Surgery
Interventions: OTHER: Variable Ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Synbiotics on the Upper Respiratory Tract Infection
Status: COMPLETED
Conditions: Upper Respiratory Tract Infection|Gut Microbiota|Immune Function
Interventions: DIETARY_SUPPLEMENT: Synbiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Home-based e-Health Intervention in the Elderly: MOVI-ageing
Status: NOT_YET_RECRUITING
Conditions: Cognitive Decline
Interventions: BEHAVIORAL: intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: First Study in Humans With GSK206136
Status: COMPLETED
Conditions: Depressive Disorder and Anxiety Disorders
Interventions: DRUG: GSK206136|DRUG: PLACEBO|RADIATION: PET
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Dietary Polyphenols and ω-3 Fatty Acids on Cardiovascular Risk Factors in High Risk Subjects
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: OTHER: Diet rich in omega-3 fatty acids|OTHER: Diet rich in polyphenols|OTHER: Control diet|OTHER: diet rich in omega-3 and polyphenols
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparing 0.5 mg Dutasteride vs Placebo Daily in Men Receiving Androgen Ablation Therapy for Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Dutasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study
Status: UNKNOWN
Conditions: Cardiovascular Diseases|NSTEMI|STEMI
Interventions: DRUG: Bempedoic Acid / Ezetimibe Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Stereotactic Radiosurgery in Treating Patients With Brain Tumors
Status: COMPLETED
Conditions: Adult Central Nervous System Germ Cell Tumor|Adult Malignant Meningioma|Adult Medulloblastoma|Adult Noninfiltrating Astrocytoma|Adult Oligodendroglioma|Adult Craniopharyngioma|Adult Meningioma|Brain Metastases|Adult Ependymoma|Adult Pineal Parenchymal Tumor|Adult Brain Stem Glioma|Adult Infiltrating Astrocytoma|Mixed Gliomas|Stage IV Peripheral Primitive Neuroectodermal Tumor
Interventions: PROCEDURE: Sterotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Thymosin α1 to Reduce Acute Pneumonia For Bulky None-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Concurrent chemotherapy|RADIATION: split-course radiotherapy|DRUG: thymosin alpha 1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corifollitropin Alfa in Participants Undergoing Repeated Controlled Ovarian Stimulation (COS) Cycles Using a Multiple Dose Gonadatropin Releasing Hormone (GnRH) Antagonist Protocol (Study 38825)(P05714)
Status: COMPLETED
Conditions: In Vitro Fertilization
Interventions: DRUG: Corifollitropin alfa|BIOLOGICAL: FSH|BIOLOGICAL: GnRH antagonist|BIOLOGICAL: (rec)hCG|DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Turoctocog Alfa in Prevention and Treatment of Bleeds in Previously Untreated Children With Haemophilia A
Status: COMPLETED
Conditions: Congenital Bleeding Disorder|Haemophilia A
Interventions: DRUG: turoctocog alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Elranatamab for Relapsed or Refractory Myeloma in Patients Previously Exposed to Three-drug Classes
Status: RECRUITING
Conditions: Multiple Myeloma in Relapse
Interventions: DRUG: Elranatamab (PF-06863135)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of BrainPort® Balance Device in Peripheral Vestibular Dysfunction.
Status: COMPLETED
Conditions: Vestibular Diseases|Gait Disorders
Interventions: DEVICE: Training with the BrainPort balance device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Difference Between Inhalation Anesthesia and Total Intravenous Anesthesia in Free Flap Surgery
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: MTA and Biodentine in Pulpotomized Primary Molars
Status: UNKNOWN
Conditions: Primary Molar Pulpotomy
Interventions: OTHER: Pulpotomy|OTHER: Pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Immunoglobulin (IVIG) in Lung Transplantation
Status: COMPLETED
Conditions: Hypogammaglobulinemia|Lung Transplantation
Interventions: DRUG: IVIG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pragmatic Amiodarone Trial to Reduce Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Surgery, Cardiac|Atrial Fibrillation
Interventions: DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ultrahigh-resolution Optical Coherence Tomography Imaging of the Anterior Eye Segment Structures
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction|Cataract|Glaucoma|Corneal Transplantation|Demodicosis|Conjunctival Pathologies|Acanthamoeba Keratitis|Aniridia
Interventions: DEVICE: Ultrahigh resolution Spectral Domain OCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Status: TERMINATED
Conditions: Urticaria
Interventions: DRUG: Methotrexate (drug)|DRUG: placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Levosimendan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: W0265-103: A Single-Center, Evaluator-Blinded, Randomized, Placebo Controlled, Phase 1 Clinical Trial Evaluating The Phototoxic Potential Of Topically Applied Clindamycin 1.0% - Tretinoin 0.025% Gel (Ct Gel) In Healthy Volunteers
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: CT Gel (clindamycin 1% and tretinoin 0.025%)|OTHER: Vehicle gel patch|OTHER: Blank patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: This Study in Patients With Chronic Lymphocytic Leukaemia is Done to Determine a Safe and Effective Dose of BI 836826 in Combination With Venetoclax
Status: WITHDRAWN
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell
Interventions: DRUG: Venetoclax|DRUG: BI 836826
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Exercise in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Newsletter about physical activity and breast cancer survivors|BEHAVIORAL: Changing your habits brochure|BEHAVIORAL: Tips for making exercise enjoyable and personally-valued|BEHAVIORAL: Testimonials from breast cancer survivors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating UCART019 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma
Status: UNKNOWN
Conditions: B Cell Leukemia|B Cell Lymphoma
Interventions: BIOLOGICAL: UCART019
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy of Different Dosages Vitamin K2
Status: COMPLETED
Conditions: Carboxylation Level|Vitamin K-dependent Proteins
Interventions: DIETARY_SUPPLEMENT: placebo|DIETARY_SUPPLEMENT: vitamin K1|DIETARY_SUPPLEMENT: vitamin K2|DIETARY_SUPPLEMENT: vitamin K2|DIETARY_SUPPLEMENT: vitamin K2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Evaluation of KX01 Ointment 1% in Japanese Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: KX01 ointment 1%|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study to Delay Renal Failure in Children With Alport Syndrome
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Ramipril|DRUG: placebo to ramipril|DRUG: Ramipril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AZD8529 Single Ascending Dose Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD8529|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Multi-center Study to Evaluate the Efficacy and Safety of Pancreatic Duct Stents Placement Before the Enucleation of Insulinoma Located in the Head and Neck of the Pancreas Near the Main Pancreatic Duct
Status: RECRUITING
Conditions: Insulinoma
Interventions: PROCEDURE: placement of pancreatic duct stents before enucleation surgery|PROCEDURE: Direct enucleation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of 3-point With 1-point Mesh Fixation in TAPP for Gilbert Type III Inguinal Hernia
Status: RECRUITING
Conditions: Hernia, Inguinal|Chronic Pain|Seroma|Recurrence|Infections|Hematoma
Interventions: PROCEDURE: Lightweight mesh fixation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Trial for Nicotinamide Riboside in Subjective Cognitive Decline and Mild Cognitive Impairment
Status: COMPLETED
Conditions: Cognition Disorders in Old Age|Mild Cognitive Impairment|Cognitive Decline
Interventions: DIETARY_SUPPLEMENT: Niagen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adjunctive Celecoxib in Childhood-onset OCD Study
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder|Pediatric Psychiatric Disorder
Interventions: DRUG: Celecoxib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Alirocumab Versus Placebo on Top of Maximally Tolerated Lipid Lowering Therapy in Patients With Hypercholesterolemia Who Have Type 1 or Type 2 Diabetes and Are Treated With Insulin (ODYSSEY DM - Insulin)
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DRUG: Alirocumab|DRUG: Placebo|DRUG: Lipid-Modifying Therapy (LMT)|DRUG: Antihyperglycemic Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Raxibacumab in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: placebo|DRUG: raxibacumab|DRUG: placebo|DRUG: raxibacumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Palliative Benefit of Involved-site Radiotherapy for Patients With Advanced-stage Diffuse Large B-cell Lymphoma
Status: RECRUITING
Conditions: Diffuse Large B-cell Lymphoma
Interventions: RADIATION: Consolidation involved-site radiotherapy (ISRT)|RADIATION: Consolidation involved-field radiotherapy (IFRT)|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: vincristine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Sensimed Triggerfish With Goldmann Applanation Tonometry and Perkins Tonometry
Status: COMPLETED
Conditions: Primary Open Angle Glaucoma
Interventions: DEVICE: Sensimed Triggerfish Sensor|DEVICE: Goldmann Applanation Tonometry, Perkins Tonometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cetuximab-IRDye 800CW and Intraoperative Imaging in Finding Pancreatic Cancer in Patients Undergoing Surgery
Status: TERMINATED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Cetuximab-IRDye800|DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 2 Safety and Exploratory Skin Lesion Measurement of TR-701 FA Study
Status: COMPLETED
Conditions: Major Cutaneous Abscess|Cellulitis|Erysipelas
Interventions: DRUG: TR701 FA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Omalizumab Efficacy in Patients With Refractory Nasal Polyps
Status: UNKNOWN
Conditions: Nasal Polyps
Interventions: DRUG: Omalizumab|DIAGNOSTIC_TEST: SNOT22 score
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neurophysiological Targets for Cognitive Training in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Auditory Cognitive Training|BEHAVIORAL: Visual Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Social Anxiety and Anxious Thinking Styles
Status: COMPLETED
Conditions: Social Anxiety
Interventions: BEHAVIORAL: Cognitive Bias Modification for Interpretation (CBM-I)|BEHAVIORAL: Sham Training Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Dyslipidemia
Interventions: DRUG: Fenofibrate 80 mg and metformin 1000 mg (fixed combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Effect of Peripheral Dexmedetomidine
Status: COMPLETED
Conditions: Third Molar Extraction
Interventions: DRUG: local dexmedetomidine|DRUG: Peripheral normal saline|DRUG: IV dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Efficacy and Safety of KM-819 Treatment to Slow the Progression of Multiple System Atrophy (MSA)
Status: RECRUITING
Conditions: Multiple System Atrophy
Interventions: DRUG: KM-819|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by Metformin
Status: COMPLETED
Conditions: Type-2 Diabetes Mellitus
Interventions: DRUG: LAF237 (vildagliptin)|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maintenance Treatment With Capecitabine Metronomic Chemotherapy and Chinese Traditional Medicine in Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Metronimic chemotherapy plus Chinese Traditional Medicine|DRUG: Metronimic chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Type 2 Diabetes|Chronic Kidney Disease
Interventions: DRUG: Dulaglutide|DRUG: Insulin glargine|DRUG: Insulin lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: high sodium diet|DRUG: low sodium diet|DRUG: ramipril 10 mg|DRUG: valsartan 160 mg|DRUG: candesartan 8 mg|DRUG: atenolol 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proton Beam Radiation Therapy and Cisplatin in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer and Positive Lymph Nodes
Status: WITHDRAWN
Conditions: Cervical Cancer|Stage IB Cervical Cancer|Stage IIA Cervical Cancer|Stage IIB Cervical Cancer|Stage III Cervical Cancer|Stage IVA Cervical Cancer
Interventions: RADIATION: proton beam radiation therapy|RADIATION: radiation therapy treatment planning/simulation|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HLT® Meridian® TAVR Valve System Early Feasibility Study for Aortic Regurgitation
Status: WITHDRAWN
Conditions: Aortic Regurgitation
Interventions: DEVICE: The HLT® Meridian® TAVR Valve (Meridian® with TriVentTM Anticalcification Treatment Valve and Pathfinder® Delivery System)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Bodies Project to Prevent Childhood Obesity
Status: COMPLETED
Conditions: Obesity, Childhood
Interventions: BEHAVIORAL: Healthy Eating, Active Play, Self-Regulation, Parent Education|BEHAVIORAL: Healthy Eating, Active Play, Self-Regulation|BEHAVIORAL: Healthy Eating, Active Play, Parent Education|BEHAVIORAL: Healthy Eating + Active Play|BEHAVIORAL: Healthy Eating, Self-Regulation, Parent Education|BEHAVIORAL: Healthy Eating + Self-Regulation|BEHAVIORAL: Healthy Eating + Parent Education|BEHAVIORAL: Healthy Eating Only|BEHAVIORAL: Active Play, Self-Regulation, Parent Education|BEHAVIORAL: Active Play + Self-Regulation|BEHAVIORAL: Active Play + Parent Education|BEHAVIORAL: Active Play Only|BEHAVIORAL: Self-Regulation + Parent Education|BEHAVIORAL: Self-Regulation Only|BEHAVIORAL: Food Literacy + Parent Education|BEHAVIORAL: Food Literacy Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Seroquel and Lithium as Monotherapy in Acute Mania Treatment in Bipolar Disorder Patients
Status: COMPLETED
Conditions: Mania|Bipolar Disorder
Interventions: DRUG: Quetiapine Fumarate|DRUG: Lithium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy Following Chemotherapy & Peripheral Stem Cell Transplantation in Treating Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: keyhole limpet hemocyanin|BIOLOGICAL: sargramostim|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Electroacupuncture to Mirabegron for Treatment of Overactive Bladder
Status: WITHDRAWN
Conditions: Overactive Bladder
Interventions: OTHER: electroacupncture|DRUG: Mirabegron 50 MG [Myrbetriq]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Portable Health Files Improve Quality of Care and Health Outcomes: a Randomized Controlled Trial
Status: UNKNOWN
Conditions: Chronic Medical Conditions|Personal Health Records|Electronic Medical Record
Interventions: DEVICE: Electronic (USB) Portable Health File|DEVICE: Paper Portable Health File
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Application of Right Atrial Left Ventricular Fusion Pacing in Patients With CRT Indications
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: CRT with LV-only pacing / bi-ventricular pacing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors
Status: RECRUITING
Conditions: EGFR-Mutated Non-Small-Cell Lung Carcinoma|Small Cell/Neuroendocrine
Interventions: DRUG: Olaparib|DRUG: Durvalumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: B-vitamin Levels and Adverse Pregnancy Outcomes
Status: COMPLETED
Conditions: Birth Defect|Pregnancy Loss|Pregnancy Complications|Pregnancy Induced Hypertension|Recurrent Pregnancy Loss|Health Problems in Pregnancy|Gestational Diabetes|Gestational Hypertension|Preterm Birth
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Comparison of Distal Radial Versus Conventional Radial Access for Coronary Angiography and Intervention
Status: UNKNOWN
Conditions: Coronary Disease
Interventions: PROCEDURE: Coronary Angiography and Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Darunavir/Cobicistat and Dolutegravir to Maintain Virologic Suppression and Reduce NRTI-associated Toxicity
Status: WITHDRAWN
Conditions: HIV/AIDS
Interventions: DRUG: Darunavir/Cobicistat|DRUG: Dolutegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GSK1322322 Versus Linezolid in the Treatment of Acute Bacterial Skin and Skin Structure Infection
Status: COMPLETED
Conditions: Skin Infections, Bacterial
Interventions: DRUG: GSK1322322|DRUG: Linezolid|DRUG: GSK1322322 placebo|DRUG: Linezolid placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation (tDCS) for Treatment of Negative Syndrome in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: eldith DC-stimulator (neuroconn, Ilmenau, Germany)|DEVICE: eldith DC-stimulator (Neuroconn, Ilmenau, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: "To Study the Impact of Balloon-occluded Retrograde Transvenous Obliteration (BRTO)/Plug Assisted Retrograde Transvenous Obliteration (PARTO) Mediated Portal Flow Modulation in Reduction of Ammonia and Improvement in Organ Volume and Functionality in Patients of Cirrhosis With LR Shunt
Status: UNKNOWN
Conditions: Liver Cirrhoses
Interventions: PROCEDURE: Plug assisted retrograde transvenous obliteration/Balloon-occluded retrograde transvenous obliteration|OTHER: Standard Medical Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Estimating The Time Course Of PF-04764793 In The Blood Following Dosing By Oral Inhalation From Dry Powder Inhalers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Treatment A|DRUG: Treatment B|DRUG: Treatment C|DRUG: Treatment D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Nasal Airflow on Upper Airway Dilator Muscles During Sleep
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea
Interventions: DRUG: Oxymetazoline Nasal Spray|DRUG: Menthol Nasal Spray|DRUG: Normal saline Nasal Spray|DEVICE: Nasal mask with partly blocked
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD
Status: COMPLETED
Conditions: Stress Disorder, Post Traumatic
Interventions: DRUG: D-Cycloserine|DRUG: Alprazolam|BEHAVIORAL: Virtual Reality Exposure Therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Obsessive Compulsive Disease
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder|Transcranial Magnetic Stimulation|Functional Magnetic Resonance Imaging|Event-Related Potentials
Interventions: DEVICE: transcranial magnetic stimulation with real coil|DEVICE: transcranial magnetic stimulation with sham coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Endoscopic Minimal Invasive Approach for Pudendal Nerve and Inferior Cluneal Nerve Neurolysis: a Clinical Study
Status: COMPLETED
Conditions: Pudendopathie|Clunealgie
Interventions: PROCEDURE: Minimal-invasive endoscopic transgluteal approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis
Status: NOT_YET_RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps
Interventions: BIOLOGICAL: CM326|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Image Quality Between New Collimator LEHRS vs Siemens LEHR on Bone Scintigraphy
Status: COMPLETED
Conditions: Comparison of Two Collimators During Bone Scintigraphy
Interventions: OTHER: Bone scintigraphy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PMCF Study on the Safety and Performance of the Zimmer® Maxera™ Acetabular System in Total Hip Arthroplasty
Status: ACTIVE_NOT_RECRUITING
Conditions: Rheumatoid Arthritis With Adequate Bone Quality|Inflammatory Arthritis|Osteoarthritis, Hip|Avascular Necrosis|Post-traumatic; Arthrosis|Congenital Hip Dysplasia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma
Status: COMPLETED
Conditions: Childhood Solid Neoplasm|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Neuroblastoma
Interventions: DRUG: Crizotinib|DRUG: Cyclophosphamide|DRUG: Dexrazoxane Hydrochloride|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Questionnaire Administration|DRUG: Topotecan Hydrochloride|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety and Efficacy of Modified-Release Prednisone (Lodotra®) Therapy in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MR prednisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without PSC 833 in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: valspodar|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Fixed-dose Safety and Efficacy Study of Asenapine for the Treatment of Acute Manic or Mixed Episode in Bipolar 1 Disorder (P05691)
Status: COMPLETED
Conditions: Bipolar 1 Disorder
Interventions: DRUG: Asenapine|DRUG: Asenapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fexinidazole in Patients With Human African Trypanosomiasis (HAT) Due to Trypanosoma Brucei Rhodesiense
Status: COMPLETED
Conditions: Trypanosoma Brucei Rhodesiense; Infection
Interventions: DRUG: Fexinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Feasibility Study of the FARAPULSE Endocardial Ablation System to Treat Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: FARAPULSE Endocardial Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI
Status: COMPLETED
Conditions: Myocardial Infarction|Ischemia
Interventions: DRUG: Abciximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-PD-1 Antibody Multimodal Combination as First-line Treatment on Time Window of Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Camrelizumab/sintilimab+ Standard chemotherapy|DRUG: Camrelizumab/sintilimab+ apatinib（Intolerance to chemotherapy / refuse chemotherapy）|DRUG: Camrelizumab/sintilimab+ apatinib+ Standard chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Petosemtamab|DRUG: Investigator's Choice|DRUG: Investigator's Choice|DRUG: Investigator's Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Observational Study of Baska Mask, a New Supraglottic Airway Device in Children
Status: COMPLETED
Conditions: Baska Mask Efficacy and Safety in Children
Interventions: DEVICE: Placement and use of Baska mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade in Patients During Laparoscopic Surgery
Status: UNKNOWN
Conditions: Pharmacokinetics
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharyngeal Electrical Stimulation for the Treatment of Post-extubation Dysphagia in Acute Stroke
Status: COMPLETED
Conditions: Stroke|Dysphagia
Interventions: DEVICE: Phagenyx-Catheter, Phagenesis Limited, UK.|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Collection for Patients With Low Grade Ovarian or Peritoneal Tumors
Status: RECRUITING
Conditions: Low Grade Ovarian Serous Adenocarcinoma|Malignant Ovarian Neoplasm|Ovarian Carcinoma|Primary Peritoneal Carcinoma|Primary Peritoneal Low Grade Serous Adenocarcinoma|Psammocarcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Vemurafenib in Participants With BRAF V600 Mutation-Positive Cancers
Status: COMPLETED
Conditions: Multiple Myeloma, Neoplasms
Interventions: DRUG: cetuximab|DRUG: vemurafenib|DRUG: vemurafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic Bronchitis
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|COPD|Chronic Bronchitis
Interventions: OTHER: Inhaled 7% HS (NaCl) home treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postoperative Pain in Children
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: OTHER: Evaluating Postoperative Pain After Root Canal Treatment with Protaper Next|OTHER: Evaluating Postoperative Pain After Root Canal Treatment with Reciproc Blue Files
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING