pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Whitsundays (Nasal) Mask Take Home Study (90 Days)
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Group A : provided with 1 Whitsundays Nasal mask without a spare mask cushion|DEVICE: Group B : provided with 1 Whitsundays Nasal mask with 2 spare mask cushions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Wake and Sleep State Transitions on a Portable Electroencephalogram (EEG) Device in Narcolepsy Type 1 (NT1) and Healthy Participants
Status: COMPLETED
Conditions: Healthy Volunteers|Narcolepsy Type 1
Interventions: DEVICE: Portable EEG Device|DEVICE: Portable ECG Device|DEVICE: Accelerometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Therapy With INTRAVIT® Tablets in Patients With Diabetic Retinopathy
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DIETARY_SUPPLEMENT: INTRAVIT ®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phenotypic and Functional Characterisation of Human B-cell Response in Pemphigus
Status: UNKNOWN
Conditions: Pemphigus Vulgaris|Pemphigus Foliaceus
Interventions: OTHER: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Investigation of Myocardial Protection Level With Specific Cardioplegia Methods in Cardiac Surgery
Status: COMPLETED
Conditions: Bypass Complication|Cardioplegia Solution Adverse Reaction|Endothelial Degeneration|Oxidative Stress|Aortic Valve Stenosis|Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Endocan, E-Selectin, TNF-alpha, Total Oxidant and Antioxidant Status
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of PET/CT vs. PET/MRI Using 2 Radiopharmaceuticals
Status: COMPLETED
Conditions: Cancer Diagnosis|Diagnostic Techniques and Procedures|Diagnostic Imaging
Interventions: DRUG: F-18 FDG|DRUG: Ga-68-DOTA-TATE|DEVICE: Positron Emission Tomography / Computed Tomography (PET/CT) Scan|DEVICE: Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Lavender Essential Oil for Delirium in Elderly Intensive Care Unit Patients: Study Protocol
Status: RECRUITING
Conditions: Delirium in Old Age
Interventions: DRUG: Lavender|BEHAVIORAL: A2F bundle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Methacholine, Long-acting M-cholinolytic and beta2-agonist on the Activity of Beta-receptors in Healthy Volunteers
Status: UNKNOWN
Conditions: Health, Subjective|Hyperreactivity, Bronchial
Interventions: DRUG: Formoterol|DRUG: Tiotropium Bromide|DIAGNOSTIC_TEST: metacholine test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Magnesium Sulphate Versus Lidocaine for Control of Emergence Hypertension
Status: UNKNOWN
Conditions: Craniotomy|Hypertension
Interventions: DRUG: Magnesium sulphate|DRUG: Lidocaine Hydrochloride|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Osteopathic Visceral Treatment in Patients With Chronic Neck Pain
Status: NOT_YET_RECRUITING
Conditions: Cervical Pain
Interventions: OTHER: Diaphragm, Stomach and Liver techniques|OTHER: Stomach and Liver techniques|OTHER: Sham technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Walking Adaptability Post-Spinal Cord Injury
Status: COMPLETED
Conditions: Incomplete Spinal Cord Injury|Brown Sequard Syndrome
Interventions: BEHAVIORAL: Locomotor Training|OTHER: Cross-Sectional Testing (No Intervention)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Medical Decision Making for Older Patients With End Stage Renal Disease
Status: RECRUITING
Conditions: Renal Disease, End Stage|Palliative Care|Decision Aids
Interventions: BEHAVIORAL: Advance Care Planning Video Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Compare the Pharmacokinetics of BR4002 and BR4002-1 in Healthy Volunteers
Status: COMPLETED
Conditions: Dementia Alzheimers
Interventions: DRUG: BR4002|DRUG: BR4002-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences
Status: RECRUITING
Conditions: Family Reported Errors and Adverse Events|Health Disparities|Family Safety Reporting|Patient Safety|Voluntary Incident Reporting|Quality Improvement
Interventions: BEHAVIORAL: Family safety reporting intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of PTB Screening in ANC in Lusaka, Zambia
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: OTHER: TB screening Questionnaire|OTHER: Sputum smear and culture (only in HIV negative women who are symptomatic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor
Status: COMPLETED
Conditions: Anemia, Aplastic
Interventions: PROCEDURE: Bone marrow transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment Resistant Disorders|Post Traumatic Stress Disorder
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Granisetron Effect on Hemodynamic Changes in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Cholelithiasis
Interventions: DRUG: Granisetron 1 Mg/mL Intravenous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Uprifosbuvir (MK-3682) + Ruzasvir (MK-8408) in Treating Hepatitis C Virus Infection Genotypes 1-6 (MK-3682-041)
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Uprifosbuvir|DRUG: Ruzasvir|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation for Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: DEVICE: transcranial direct current stimulation|DEVICE: sham transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil to Prevent Asthma Exacerbations in Patients With ALOX5 Polymorphisms
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: EPA enriched fish oils|DIETARY_SUPPLEMENT: EPA enriched fish oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study of How a New Medicine Called Amycretin, Given as Tablets, Works in Japanese Men With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: NNC0487-0111|DRUG: Placebo (NNC0487-0111)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Capecitabine on the Pharmacokinetics of BMS-247550 and BMS-247550 on the Pharmacokinetics of Capecitabine and Its Metabolites in Patients With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Solid Tumors|Neoplasms
Interventions: DRUG: Ixabepilone|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Maintenance Infusion in Labouring Women Undergoing Cesarean Delivery: an Up-down Sequential Allocation Study
Status: RECRUITING
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Dexchlorpheniramine + Betamethasone|DRUG: Desloratadine + Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GILT Docetaxel - Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms
Interventions: DRUG: Docetaxel/DDP|DRUG: docetaxel/gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vagal Nerve Stimulation Assessed by the Diving Reflex: An Investigation Into Mechanisms of Asthma Death
Status: COMPLETED
Conditions: Asthma|Syncope
Interventions: PROCEDURE: Simulated dive reflex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of an Active Coping Program in Patients With Persistent Post-Covid Pain.
Status: ACTIVE_NOT_RECRUITING
Conditions: Long COVID|Pain
Interventions: BEHAVIORAL: Pain Neuroscience Education (PNE)+ Therapeutic Exercise (TE)|BEHAVIORAL: Active Comparator: Usual treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study
Status: NOT_YET_RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma|Multiple Myeloma, Refractory
Interventions: DRUG: Pomalidomide 4 mg every day in cycle 1|DRUG: Pomalidomide 4 mg every other day in cycle 2|DRUG: Pomalidomide 2 mg every day in cycle 2|DRUG: Pomalidomide 2 mg every day in cycle 3|DRUG: Pomalidomide 4 mg every other day in cycle 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II, Open-Label, Multicenter Study of Capmatinib in Subjects With MET Exon 14 Skipping Mutation Positive, Advanced, NSCLC With Brain Metastases
Status: WITHDRAWN
Conditions: Non-small Cell Lung Carcinoma (NSCLC)
Interventions: DRUG: Capmatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of PCIT-ED in School for Preschoolers in Poverty
Status: COMPLETED
Conditions: Childhood Mental Disorder
Interventions: BEHAVIORAL: PCIT-ED|BEHAVIORAL: Parenting Wisely
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Expanded Access to Venetoclax
Status: AVAILABLE
Conditions: Chronic Lymphocytic Leukemia (CLL)|Multiple Myeloma|Acute Myeloid Leukemia (AML)|Non-Hodgkin's Lymphoma|Acute Lymphoblastic Leukemia (ALL)|Amyloidosis|Plasma Cell Leukemia
Interventions: DRUG: Venetoclax
Study Type: EXPANDED_ACCESS
Clinical trial: Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia
Interventions: DEVICE: active intermittent Theta Burst Stimulation (iTBS)|DEVICE: sham intermittent Theta Burst Stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stellate Ganglion Block for Major Depressive Disorder.
Status: COMPLETED
Conditions: Treatment Resistant Depression|Major Depressive Disorder
Interventions: DRUG: Bupivacaine Hydrochloride|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Testing the Addition of an Anti-Cancer Immunotherapy Drug, Avelumab, to Gemcitabine and Carboplatin Chemotherapy Prior to Surgery in Muscle Invasive Urinary Tract Cancer vs. Surgery Alone in Patients Who Are Not Able to Receive Cisplatin Therapy (SWOG GAP TRIAL)
Status: SUSPENDED
Conditions: Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall|Infiltrating Renal Pelvis and Ureter Urothelial Carcinoma|Stage II Bladder Cancer AJCC v8
Interventions: PROCEDURE: Therapeutic Conventional Surgery|DRUG: Avelumab|DRUG: Gemcitabine Hydrochloride|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients.
Status: COMPLETED
Conditions: Hypertension, Pregnancy Induced|Hydralazine Adverse Reaction|Pre-eclampsia|Pre-eclampsia Superimposed Pre-existing Hypertension
Interventions: DRUG: Labetalol|DRUG: Hydralazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Computer- Assisted Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism|Asperger's Syndrome|Generalized Anxiety Disorder|Social Phobia|Separation Anxiety Disorder|Obsessive-compulsive Disorder
Interventions: BEHAVIORAL: Computer assisted cognitive behavioral therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of BAY 43-9006 (Sorafenib) on Cardiovascular Safety Parameters in Cancer Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Sorafenib (Nexavar, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study of VERVE-101 in Patients With Familial Hypercholesterolemia and Cardiovascular Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Heterozygous Familial Hypercholesterolemia|Atherosclerotic Cardiovascular Disease|Hypercholesterolemia
Interventions: DRUG: VERVE-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by Azacytidine
Status: UNKNOWN
Conditions: Myeloid Leukemia|Myelodysplastic Syndromes
Interventions: OTHER: blood samples|DRUG: azacytidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biopsy of Calcifications Under Contrast Enhancement Guide (BoCCE)
Status: UNKNOWN
Conditions: Breast Cancer|Calcification
Interventions: OTHER: Contrast enhanced mammography guided biopsy (diagnostic procedure)|OTHER: Mammography guided biopsy (diagnostic procedure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Determination of Optimal Sleep Treatment Elements - MOST
Status: ACTIVE_NOT_RECRUITING
Conditions: Insomnia Chronic
Interventions: BEHAVIORAL: Sleep Optimization|BEHAVIORAL: Stimulus Control Therapy|BEHAVIORAL: Relaxation Training|BEHAVIORAL: Cognitive Therapy|BEHAVIORAL: Sleep Hygiene Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cabozantinib in High Grade Neuroendocrine Neoplasms
Status: RECRUITING
Conditions: High Grade Neuroendocrine Neoplasms
Interventions: DRUG: Cabozantinib|PROCEDURE: Blood for plasma biomarkers|PROCEDURE: Tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Impact of Serratus Intercostal Plane Block in Video Assisted Thoracic Surgery
Status: COMPLETED
Conditions: Anesthesia, Conduction
Interventions: PROCEDURE: SIP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy of Irinotecan Versus Oxaliplatin in the First-line Treatment of Refractory Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: mCRC
Interventions: DRUG: Irinotecan|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Acetazolamide on Intraocular Pressure After Being in the Trendelenburg Position.
Status: COMPLETED
Conditions: IOP
Interventions: DRUG: Acetazolamide|DRUG: Placebo|OTHER: Trendelenburg Position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Bridging Trial Comparing Sugammadex (Org 25969) at 1-2 Post-Tetanic Count (PTC) in Caucasian Participants. Part B (P05974)
Status: COMPLETED
Conditions: Anesthesia, General
Interventions: DRUG: Sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine for the Treatment of Delirium After Heart Surgery
Status: TERMINATED
Conditions: Postoperative|Delirium|Psychomotor|Confusion
Interventions: DRUG: Dexmedetomidine|DRUG: Haloperidol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment With PTH After Sternotomy in Cardiac Surgery Patients
Status: COMPLETED
Conditions: Disruption or Dehiscence of Closure of Sternum or Sternotomy
Interventions: DRUG: Parathyroid hormone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Paclitaxel + Carboplatin With/ut BMS-275291 in Advanced or Metastatic Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: rebimastat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anecortave Acetate in Subfoveal Choroidal Neovascularization (CNV) Due to Wet Age-Related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Macular Degeneration|Maculopathy, Age-Related|Age-Related Maculopathies|Age-Related Maculopathy|Maculopathies, Age-Related
Interventions: DRUG: Anecortave Acetate 15 mg sterile suspension|OTHER: Anecortave Acetate Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Performance and Safety of a Medical Device Developed to Improve the Reading of Dyslexic Patients
Status: COMPLETED
Conditions: Dyslexia
Interventions: DEVICE: Scintilling lamp|DEVICE: Classic lamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peptide-pulsed vs. RNA-transfected Dendritic Cell Vaccines in Melanoma Patients
Status: COMPLETED
Conditions: Melanoma Stage III or IV
Interventions: BIOLOGICAL: autologous dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TSA-DC Vaccine in Treating Patients With Gastrointestinal Solid Tumor
Status: UNKNOWN
Conditions: Tumor Gastric|Tumor, Colorectal
Interventions: BIOLOGICAL: Tumor Specific Antigen-loaded Dendritic Cells|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis
Status: ENROLLING_BY_INVITATION
Conditions: Osteoarthritis|Osteoarthritis Thumb Base Joint|Carpometacarpal Osteoarthritis|Thumb
Interventions: DEVICE: CTM|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of WB-EMS in Ulcerative Colitis Patients
Status: WITHDRAWN
Conditions: Ulcerative Colitis
Interventions: OTHER: active Whole Body Electromyostimulation|OTHER: Passive WB-EMS|DEVICE: WB-EMS application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Behavioural Weight Loss Intervention Delivered in Cardiac Rehabilitation for Patients With Atrial Fibrillation and Obesity
Status: RECRUITING
Conditions: Atrial Fibrillation|Obesity
Interventions: BEHAVIORAL: BWLT+CR|BEHAVIORAL: CR-Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Conversational IT for Better, Safer Pediatric Primary Care
Status: COMPLETED
Conditions: Preventive Care|Medication Management
Interventions: BEHAVIORAL: Safety Training|BEHAVIORAL: Personal Health Partner and Counseling (PHP+C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer|Colorectal Cancer|Non-Small Cell Lung Cancer
Interventions: BIOLOGICAL: AMG820 and pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Pharmacokinetic Profile, Safety and Tolerability of Sildenafil (REVATIO®) in Cardiac Surgery
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Providers Against Cavities in Children's Teeth
Status: COMPLETED
Conditions: Dental Caries
Interventions: BEHAVIORAL: CSM theory-based didactic education and skills training|OTHER: AAP-based didactic education|OTHER: Practice EMR changes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Function and Autonomic Regulation in Patients With Migraine
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DIAGNOSTIC_TEST: Cognition|DIAGNOSTIC_TEST: Sympathetic Nervous System|DIAGNOSTIC_TEST: Concentratio and Attention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Anesthesia and Postoperative Outcome in Colorectal Cancer Patients
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: TIVA+lidocaine|DRUG: Sevoflurane+lidocaine|DRUG: TIVA+placebo|DRUG: Sevoflurane+placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric
Status: COMPLETED
Conditions: Specified Sedative|Hypnotic
Interventions: DRUG: Diphenhydramine|DRUG: normal saline|DRUG: Ketamine|DRUG: Sevoflurane|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inflammation and Threat Sensitivity in PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BIOLOGICAL: Typhoid Vi Polysaccharide Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Adding Nalbuphine for Control of Intrathecal Morphine Pruritus
Status: UNKNOWN
Conditions: Pruritus|Pain, Postoperative|Nausea, Postoperative|Vomiting, Postoperative
Interventions: DRUG: Morphine 10 MG/ML|DRUG: Nalbuphine Hydrochloride 10 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nebivolol and the Endothelin (ET)-1 System
Status: COMPLETED
Conditions: Prehypertension|Hypertension
Interventions: DRUG: Nebivolol|DRUG: Metoprolol|DRUG: Placebo|OTHER: Forearm Blood Flow (FBF) response to BQ-123 (100 mol/min)|OTHER: FBF response to BQ-123 (100 nmol/min)+BQ-788(50 nmol/min)|OTHER: FBF response to Acetylcholine|OTHER: FBF response to Sodium Nitroprusside|OTHER: FBF response to BQ-123+BQ-788+ACh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Alprostadil in Maculopathy Study (AIMS)
Status: TERMINATED
Conditions: Macular Degeneration
Interventions: DRUG: Alprostadil (prostaglandin E1)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: "Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Hypoxia|Hypercapnia|Sleep Disorders|Obesity|Hypertension|Coronary Artery Vasospasm|Right Ventricular Overload|Left Ventricular Function Systolic Dysfunction|Ventricular Hypertrophy
Interventions: OTHER: Clinically prescribed CPAP therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of WPV01 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: WPV01 Dose 1-4|DRUG: WPV01 Dose 5-8 and Ritonavir|DRUG: WPV01 Dose 9-12|DRUG: WPV01 Dose 13-15 and Ritonavir|DRUG: WPV01 Dose 16
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab Plus Lenvatinib In Second Line and Third Line Malignant Pleural mesotheLioma Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Mesotheliomas Pleural
Interventions: DRUG: Pembrolizumab|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
Status: RECRUITING
Conditions: Sarcopenia|Cirrhosis, Liver|Malnutrition; Protein
Interventions: DIETARY_SUPPLEMENT: Aminolife Plus by Piemme Pharmatech, Italy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Financial Incentives for Smoking Treatment
Status: COMPLETED
Conditions: Smoking|Smoking, Tobacco|Tobacco Use Disorder
Interventions: BEHAVIORAL: Smoking cessation counseling (Quitline)|BEHAVIORAL: Smoking cessation pharmacotherapy (e.g, nicotine replacement therapy)|BEHAVIORAL: Financial incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Perioperative i.v. Low-dose S(+) Ketamine
Status: COMPLETED
Conditions: Hemorrhoids|Pain
Interventions: DRUG: S (+) Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study Designed to Assess the Efficacy of the ActiLady Device in Adult Female Subjects With Dysmenorrhea
Status: COMPLETED
Conditions: Dysmenorrhea
Interventions: DEVICE: Miniature Actilady device active|DEVICE: Miniature Actilady device not active
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Appropriate Remifentanil Dose for Optimal Insertion of Laryngeal Mask Airway in Adult Patients During Induction of General Anesthesia Using Remimazolam.
Status: RECRUITING
Conditions: Adult, Laryngeal Masks, Remimazolam, Remifentanil
Interventions: DRUG: remifentanil of the assigned dose|DEVICE: Ambu Auragain for airway management
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells
Status: RECRUITING
Conditions: Unresectable Metastatic Colorectal Cancer
Interventions: DRUG: CYAD-101|DRUG: FOLFOX|DRUG: FOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel, Carboplatin, and Capecitabine as Treatment for Patients With Locally Advanced or Inflammatory Breast Cancer Before Surgery
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: neoadjuvant chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aprepitant for Prevention of Postoperative Nausea and Vomiting in Elective Hysterectomy
Status: TERMINATED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a GLP-1 Agonist
Status: ACTIVE_NOT_RECRUITING
Conditions: Overweight and Obesity|Healthy
Interventions: DRUG: NG101|DRUG: Placebo|DRUG: Semaglutide Injectable Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phosphate Intake's Effect on the Skeletal System - Pilot
Status: COMPLETED
Conditions: Healthy|Kidney Failure, Chronic
Interventions: BEHAVIORAL: dietary phosphorus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.
Status: RECRUITING
Conditions: Hypertension Arterial|Hypokinetic|Cardiomyopathies|Left Ventricular Hypertrophy
Interventions: OTHER: Determine the etiology of hypokinetic and hypertrophic heart disease on transthoracic echocardiography data alone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Emergency Contraception as a Back up of Lactational Amenorrhea Method(LAM)
Status: COMPLETED
Conditions: Pregnancy During Breastfeeding|Lactational Amenorrhea Method
Interventions: DRUG: Counseling for LAM+ LNG-EC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 129Xe MRI in Pediatric Population With BPD
Status: NOT_YET_RECRUITING
Conditions: Bronchopulmonary Dysplasia
Interventions: COMBINATION_PRODUCT: MagniXene, hyperpolarized 129Xe MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Non-Myeloablative Therapy in Patients With High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: 3F8 and 13-cis-retinoic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Barium Enema, Computed Tomographic Colonography, and Colonoscopy in Detecting Colon Cancer
Status: TERMINATED
Conditions: Colorectal Cancer
Interventions: OTHER: screening questionnaire administration|PROCEDURE: barium enema injection|PROCEDURE: computed tomography|PROCEDURE: computed tomography colonography|PROCEDURE: diagnostic colonoscopy|PROCEDURE: screening colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Trial Assessing the Effectiveness of Ivabradine Started at Discharge From the Observation Unit
Status: RECRUITING
Conditions: Heart Failure
Interventions: DRUG: Ivabradine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Levo Phencynonate Hydrochloride for the Prevention of Seasickness
Status: COMPLETED
Conditions: Motion Sickness
Interventions: DRUG: placebo|DRUG: levo phencynonate hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Microplasmin Administered Via the Trellis-8 Infusion System for Treatment of Acute Iliofemoral DVT
Status: TERMINATED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: microplasmin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye
Status: TERMINATED
Conditions: Non Infectious Uveitis
Interventions: DRUG: DE-109 Intravitreal Injections|OTHER: Sham Procedure|DRUG: DE-109 Intravitreal Injections|DRUG: DE-109 Intravitreal Injections (Open Label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects
Status: ENROLLING_BY_INVITATION
Conditions: Bipolar I Disorder|Schizophrenia
Interventions: DRUG: OLZ/SAM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prognostic Value of Exhaled Isoprene Levels for Morbidity and Functional Outcome in Cardiosurgical Patients
Status: RECRUITING
Conditions: Frailty|Muscle Weakness|Volatile Organic Compounds|Isoprene
Interventions: DIAGNOSTIC_TEST: Physical performance testing|DIAGNOSTIC_TEST: Breath sampling and VOC analysis|DIAGNOSTIC_TEST: Muscle ultrasound|DIAGNOSTIC_TEST: Blood-based biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Cor Pulmonale
Interventions: OTHER: High Frequency Oscillation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Pediatric Drug Study to Determine the Long-term Safety and Tolerability in Children and Adolescents (4-17 Years in Age) Taking the Drug
Status: WITHDRAWN
Conditions: Epilepsy
Interventions: DRUG: Eslicarbazepine acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of SGLT-2 Inhibitors on Cardiac Remodeling in Post Myocardial Infarction Patients
Status: COMPLETED
Conditions: Myocardial Infarction|Diabetes Mellitus, Type 2|Myocardial Remodeling, Ventricular
Interventions: DRUG: Dapagliflozin 10Mg Tab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Intermittent Oral Tube in Alzheimer's Patients
Status: NOT_YET_RECRUITING
Conditions: Alzheimer Disease
Interventions: BEHAVIORAL: Conventional Care|DEVICE: Intermittent Oral-esophageal Tube Feeding|DEVICE: Nasogastric tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a mHealth Platform for Diarrheal Disease Decision-support
Status: COMPLETED
Conditions: Diarrhea
Interventions: OTHER: Smartphone-based decision-support|OTHER: Paper-based decision-support|OTHER: Pre-Assessment of practices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy
Status: WITHDRAWN
Conditions: Colorectal Neoplasms
Interventions: DEVICE: Narrow band imaging|OTHER: Chromoendoscopy|OTHER: High definition white light endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Benefits of a Bolus Calculator in Pediatric Patients on Multiple Daily Insulin Injections
Status: COMPLETED
Conditions: Poor Glycemic Control|Quality of Life
Interventions: DEVICE: accu chek Aviva Expert|DEVICE: Accu Chek Aviva Nano
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PEARL Intervention to Reduce Depression Among Adults With Epilepsy
Status: UNKNOWN
Conditions: Depression|Epilepsy
Interventions: BEHAVIORAL: Program to Encourage Active, Rewarding Lives (PEARL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Oxybutynin to Treat Axillary Hyperhidrosis
Status: COMPLETED
Conditions: Axillary Hyperhidrosis|Osmidrosis
Interventions: DRUG: Oxybutynin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Magrolimab Given Together With FOLFIRI/BEV in Patients With Previously Treated Advanced Inoperable Metastatic Colorectal Cancer (mCRC)
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Magrolimab|DRUG: Bevacizumab|DRUG: Irinotecan|DRUG: Fluorouracil|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Cytoreduction Followed by Chemotherapy Versus Chemotherapy Alone in Relapsed Ovarian Cancer After PARPi Maintenance Treatment: a Multicentre, Open-label, Randomised, Phase 3 Trial
Status: RECRUITING
Conditions: Relapsed Ovarian Cancer
Interventions: PROCEDURE: Secondary cytoreduction|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block for Peroperative Analgesia and Intraabdominal Tissue Oxygenation
Status: COMPLETED
Conditions: Lower Abdominal Surgery
Interventions: DRUG: Bupivacaine and Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neuropsychological and Neuroimaging Evaluation of the Cognitive Impairment in Aortic Valve Replacement (ARTiCO)
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Transcatheter Aortic Valve Replacement|Surgical Treatment|Cognitive Impairment|Stroke
Interventions: PROCEDURE: Aortic valve replacement|DEVICE: TAVI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Learn About Abrocitinib Tablets in People With Atopic Dermatitis in India
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: Abrocitinib 100 mg|DRUG: Abrocitinib 200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Deep Neuromuscular Block on Surgical Conditions in Morbidly Obese Patients
Status: COMPLETED
Conditions: Surgical Conditions
Interventions: DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sevelamer Carbonate on Oxidative Stress in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy
Interventions: DRUG: Sevelamer Carbonate|DRUG: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome|Myalgic Encephalomyelitis
Interventions: DRUG: Clonidine|DRUG: Lactose capsula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorpheniramine Nasal Spray to Accelerate COVID-19 Clinical Recovery in an Outpatient Setting: ACCROS-III
Status: COMPLETED
Conditions: COVID-19|Symptoms and Signs|COVID-19 Pandemic|Coronavirus Disease 2019|Coronavirus Infections
Interventions: COMBINATION_PRODUCT: Chlorpheniramine Maleate 0.4% Nasal Spray|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-reflux Medication as a Potential Treatment for Glue Ear in Children
Status: COMPLETED
Conditions: Otitis Media With Effusion
Interventions: DRUG: Lansoprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gadobutrol Magnevist-controlled Body Study
Status: COMPLETED
Conditions: Magnetic Resonance Imaging
Interventions: DRUG: Gadobutrol (Gadovist, BAY86-4875)|DRUG: Gadopentetate Dimeglumine (Magnevist, BAY86-4882)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Belatacept in De Novo Heart Transplantation
Status: RECRUITING
Conditions: Heart Transplantation
Interventions: DRUG: Belatacept|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Clear Cell Cystadenocarcinoma|Stage III Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: Docetaxel|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF)
Status: RECRUITING
Conditions: Cystic Fibrosis
Interventions: DEVICE: a skin-interfaced colorimetric bifluidic sweat device with two synchronous channels|OTHER: Standard of Care laboratory procedure for measurement of sweat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: CPT Group for DBT Clients With Co-Occurring Borderline Personality Disorder and PTSD
Status: COMPLETED
Conditions: Borderline Personality Disorder|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Blood Saving Effect of Tranexamic Acid in Total Knee Arthroplasty With Rivaroxaban as Thromboprophylaxis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Tranexamic Acid 5%,5ml/amp (intraoperative)|DRUG: Tranexamic Acid 5%,5ml/amp (3 hours after operation)|DRUG: 0.9% Normal Saline (intraoperative)|DRUG: 0.9% Normal Saline (3 hours after operation)|DRUG: rivaroxaban (10mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION