pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
Status: COMPLETED
Conditions: Post-operative Complications|Surgical Site Infection|Surgical Wound Infection
Interventions: DEVICE: Prevena™ Incision Management System (PIMS)|DEVICE: Standard-of-care Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: N-butyl-2-cyanoacrylate, Iso-amyl-2-cyanoacrylate and Hypertonic Glucose With 72% Chromated Glycerin in Gastric Varices
Status: COMPLETED
Conditions: Gastric Varices
Interventions: PROCEDURE: injection sclerotherapy for gastric varices
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decreasing the Invasiveness of Ultrasound Guided Caudal Block: A Comparison Between 22-gauge and 27-guage Needles
Status: COMPLETED
Conditions: Anesthesia|Pain|Caudal Block|Pediatric Anesthesia|Abdominal Surgeries
Interventions: DEVICE: The use of classical Gauge 22 needle|DEVICE: The use of classical Gauge 27 needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Motivational Interviews on Cardiovascular Disease Risks and Healthy Lifestyle Behavior Changes
Status: COMPLETED
Conditions: Essential Hypertension|Motivational Interview|Cardiovascular Disease Risk|Healthy Lifestyle Behavior
Interventions: BEHAVIORAL: 6-session motivational interviews|OTHER: Health education structured according to the health belief model|OTHER: Training booklet prepared by the researchers on healthy lifestyle behavior changes|OTHER: 6 month follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Cardiovascular Assessment of Ponatinib as Third Line Treatment in Chronic Phase Chronic Myeloid Leukemia
Status: NOT_YET_RECRUITING
Conditions: Chronic Myeloid Leukemia (CML)
Interventions: DRUG: Ponatinib 15mg QD|DRUG: Ponatinib 30mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methylprednisolone Replacement for Dexamethasone-induced Hiccup
Status: WITHDRAWN
Conditions: Dexamethasone|Hiccup
Interventions: DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation
Status: COMPLETED
Conditions: Tobacco Dependence
Interventions: DRUG: Varenicline, Nicotine Patch|DRUG: Varenicline and Placebo Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Extended Peri-operative Tinzaparin to Improve Disease-free Survival in Patients With Resectable Colorectal Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Colon
Interventions: DRUG: Tinzaparin|DRUG: Tinzaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Acceptability and Preliminary Effectiveness of PC-515 for Vaginal Use as a Possible Microbicide
Status: COMPLETED
Conditions: HIV Infections|Chlamydia Trachomatis|Neisseria Gonorrhoeae|Trichomonas Vaginitis|Syphilis|Herpes Simplex
Interventions: DRUG: Carraguard (PC-515)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: OTHER
Clinical trial: Domperidone as a Treatment for Dopamine Agonist-induced Peripheral Edema in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease|Peripheral Edema
Interventions: DRUG: Domperidone (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders
Status: COMPLETED
Conditions: Functional Bowel Disorder
Interventions: DRUG: Mebeverine+Simethicone|DRUG: Mebeverine|DRUG: Simethicone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sonobiopsy for Noninvasive and Sensitive Detection of Glioblastoma
Status: RECRUITING
Conditions: Glioblastoma|Glioblastoma Multiforme
Interventions: DEVICE: Sonobiopsy|PROCEDURE: Research blood|GENETIC: Cancer Personalized Profiling|DEVICE: Definity®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUD
Status: UNKNOWN
Conditions: Menorrhagia
Interventions: DRUG: Tranexamic Acid|DRUG: Diosmin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of the Biceps With Concomitant Supraspinatus Tears
Status: RECRUITING
Conditions: Supraspinatus Tear
Interventions: PROCEDURE: LHB Tenotomy|PROCEDURE: LHB Tenodesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Research of CAR T Cells Targeting CEA Positive Colorectal Cancer (CRC)
Status: UNKNOWN
Conditions: Stage III Colorectal Cancer|Colorectal Cancer Liver Metastasis
Interventions: BIOLOGICAL: Anti-CEA-CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Simplified Kaletra® (Lopinavir/Ritonavir)-Based Therapy Versus a Sustiva® (Efavirenz)-Based Standard of Care in Previously Non-Treated HIV-Infected Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Kaletra® (lopinavir/ritonavir)|DRUG: Combivir® (lamivudine, zidovudine)|DRUG: Sustiva® (efavirenz)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial Fibrillation
Status: TERMINATED
Conditions: Symptomatic Paroxysmal Atrial Fibrillation
Interventions: PROCEDURE: Arctic Front® catheter vs. HD Mesh Ablator® catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lycopene Following Aneurysmal Subarachnoid Haemorrhage
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage|Aneurysm
Interventions: DRUG: Lycopene|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Improving Well-Being for Older Adult Family Dementia Caregivers
Status: COMPLETED
Conditions: Stress, Psychological
Interventions: BEHAVIORAL: Mindfulness Based Stress Reduction Program|BEHAVIORAL: Living Well Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants
Status: COMPLETED
Conditions: No Evidence of Disease|Prostate Carcinoma
Interventions: DIETARY_SUPPLEMENT: Selenium|OTHER: Placebo|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Methylselenocysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cell Infusion Intraportal Autologous Bone Marrow Mononuclear as Enhancer of Liver Regeneration
Status: COMPLETED
Conditions: Liver Transplant Rejection
Interventions: OTHER: Cell infusion intraportal mononuclear bone marrow autologous and portal embolization of the affected segments.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trials of Intelligent Nighttime Brace With Smart Padding to Treat of Adolescent Idiopathic Scoliosis
Status: ENROLLING_BY_INVITATION
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DEVICE: Intelligent Nighttime Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metatarsophalangeal Joint Sprain Kinesiotaping
Status: COMPLETED
Conditions: Turf Toe|Metatarsophalangeal (Joint) Sprain
Interventions: OTHER: Traditional physical therapy program|OTHER: Kinsio taping|OTHER: placebo Kinsio taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas
Status: COMPLETED
Conditions: Non-Hodgkin's Disease
Interventions: BIOLOGICAL: Nivolumab|DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
Status: TERMINATED
Conditions: Bladder Cancer|Urothelial Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: UGN-102|PROCEDURE: TURBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Erector Spinae Plane Block and Oblique Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: ESP Block|PROCEDURE: OSTAP block|OTHER: Standard Pain Followup and Monitorization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structured Function-Based Elopement Treatment Program
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Function-Based Elopement Treatment (FBET)|BEHAVIORAL: Parent Education Program (PEP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Personalized Feedback for Distress Intolerant Smokers
Status: COMPLETED
Conditions: Anxiety Disorders|Depression|Psychological Distress|Tobacco Dependence|Smoking, Tobacco|Smoking, Cigarette
Interventions: BEHAVIORAL: PFI for Smoking & Distress Tolerance|BEHAVIORAL: PFI for Smoking Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Arterial pH and Total Body Nitrogen Balances in APD
Status: COMPLETED
Conditions: End-stage Renal Disease
Interventions: DRUG: ammonium chloride or sodium citrate/citric acid|DRUG: Sodium citrate/citratic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intra-discal Steroid Injection for MODIC I Discopathy
Status: COMPLETED
Conditions: Back Pain Lower Back Chronic
Interventions: DRUG: Visipaque - Hydrocortancyl|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial
Status: COMPLETED
Conditions: Cataracts|Astigmatism
Interventions: DEVICE: Abbott WHITESTAR Signature System with Ellips Transversal Ultrasound|DEVICE: Alcon Infiniti wiht the OZIL Torsional Handpiece
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel, Carboplatin, and Oral Etoposide Followed by Weekly Paclitaxel in High Grade Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: LUM/IVA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm
Status: RECRUITING
Conditions: Bedwetting|Nocturnal Enuresis|Urinary Incontinence
Interventions: DEVICE: gogoband|DEVICE: SNEA group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraarticular Antibiotic in TKA
Status: COMPLETED
Conditions: Antibotics in Cementless Knees
Interventions: DRUG: Tobramycin Powder|DEVICE: Vancomyscin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine Used With Treatment Resistant Depression in Older Adults
Status: COMPLETED
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: venlafaxine XR|DRUG: buprenorphine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Itraconazole in Treating Patients With Biochemically Relapsed Prostate Cancer
Status: COMPLETED
Conditions: Prostate Adenocarcinoma|Recurrent Prostate Carcinoma|Stage I Prostate Adenocarcinoma AJCC v7|Stage II Prostate Adenocarcinoma AJCC v7|Stage III Prostate Adenocarcinoma AJCC v7
Interventions: DRUG: Itraconazole|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Well the Study Treatment Finerenone Works and How Safe it is in People With Long-term Decrease in the Kidneys' Ability to Work Properly (Chronic Kidney Disease) Together With Type 1 Diabetes
Status: RECRUITING
Conditions: Chronic Kidney Disease|Type 1 Diabetes Mellitus
Interventions: DRUG: Finerenone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Immersive Virtual Reality Dietician Program in Metabolic-dysfunction Associated Steatotic Liver Disease
Status: RECRUITING
Conditions: Fatty Liver, Nonalcoholic|Weight Loss|Virtual Reality|Implementation Science
Interventions: BEHAVIORAL: In-person dietary weight loss counseling|BEHAVIORAL: Virtual reality dietary weight loss counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Study of the Natural History of Patients With Type 2 and 3 Spinal Muscular Atrophy
Status: COMPLETED
Conditions: Type 2 Spinal Muscular Atrophy|Type 3 Spinal Muscular Atrophy
Interventions: OTHER: Strength, function and activity measurements|OTHER: Muscle MRI|OTHER: Electrophysiology measurements|OTHER: Blood sampling for biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects Grapes on Health Indices
Status: COMPLETED
Conditions: Obesity|Inflammation|Cardiovascular Disease|Oxidative Stress
Interventions: OTHER: Grape in the form of freeze-dried whole grape powder|OTHER: Grape powder placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab and Combination Chemotherapy in Treating Patients With Locally Recurrent or Metastatic Urinary Tract Cancer
Status: COMPLETED
Conditions: Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter|Recurrent Bladder Cancer|Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter|Squamous Cell Carcinoma of the Bladder|Stage IV Bladder Cancer|Transitional Cell Carcinoma of the Bladder
Interventions: BIOLOGICAL: trastuzumab|DRUG: paclitaxel|DRUG: carboplatin|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Adenosquamous Carcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Recurrent Uterine Corpus Carcinoma
Interventions: DRUG: Akt Inhibitor MK2206|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Milk Formula Supplemented With L. Reuteri on Crying Time in Colicky Infants Less Than 3 Months Old
Status: UNKNOWN
Conditions: Infantile Colic
Interventions: DIETARY_SUPPLEMENT: Nidina|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Smoking Young Asthmatics: Change of Inflammation During Tobacco Cessation and Steroid Treatment
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-54767414 (Daratumumab) in Combination With Lenalidomide and Dexamethasone in Japanese Participants With Previously Untreated Multiple Myeloma Who Are Ineligible for High-dose Therapy and Autologous Stem Cell Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Daratumumab (16 mg/kg)|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Corrected Flow Time in the Carotid Artery as a Predictor of Fluid Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume in the Intensive Care Unit
Status: COMPLETED
Conditions: Hypovolemic
Interventions: DEVICE: Ultrasonographic measurement of corrected flow time in carotid artery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Unstable Kneecap - the Impact of Anatomy on Function
Status: COMPLETED
Conditions: Patellar Dislocation
Interventions: OTHER: Gait analysis|OTHER: Electromyography|PROCEDURE: Intra-operative tracking and pressure measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Rectal Tacrolimus in the Treatment of Resistant Ulcerative Proctitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Rectal tacrolimus|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Maintenance of Hemoglobin Levels, Safety and Tolerability of Once Every 4 Weeks Mircera Versus Epoetin Beta in Dialysis Patients With Chronic Renal Anemia.
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: epoetin beta|DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transesophageal Echocardiology Measured Left Ventricular End Diastolic Area as Guide for Fluid Therapy in Major Oncosurgeries
Status: COMPLETED
Conditions: Fluid Therapy DURING SURGERY
Interventions: PROCEDURE: LVEDA cm2 guided intraoperative fluid in TEE /Study Group|PROCEDURE: CVP guided intraoperative fluid in CVP / Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Taurolidin on Prevention of Bloodstream Infection
Status: TERMINATED
Conditions: Sepsis
Interventions: DEVICE: Taurolidine|DEVICE: Physiologic Serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Expanding the Pool in Orthotopic Heart Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatitis C|Heart Transplant|Cardiac Transplant
Interventions: DRUG: sofosbuvir/velpatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Intermittent Theta Burst for the Treatment of Alcohol Use Disorders in Veterans
Status: TERMINATED
Conditions: Alcohol Use Disorder|Depressive Disorder|Cigarette Smoking
Interventions: DEVICE: Intermittent theta burst transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Companion for CAR-T Web App During Chimeric Antigen Receptor T-cell Therapy
Status: WITHDRAWN
Conditions: Lymphoma|Leukemia|Plasma Cell Dyscrasia
Interventions: OTHER: Web Application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Breast/Evaluation of Cryotherapy and TRPA1 Receptors in Chemotherapy Induced Neuropathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Peripheral Neuropathies
Interventions: DEVICE: Cryotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors|Metastatic Cancer
Interventions: DRUG: temozolomide|OTHER: laboratory biomarker analysis|OTHER: liquid chromatography|OTHER: mass spectrometry|OTHER: pharmacological study|PROCEDURE: conventional surgery|RADIATION: stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Mandala Coloring Applied to Caregivers Caring for Palliative Care Patients on Perceived Stress, Anxiety Level, and Quality of Life
Status: COMPLETED
Conditions: Perceived Stress|Anxiety Level|Quality of Life
Interventions: BEHAVIORAL: Perceived Stress, Mandala application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ABSORB Clinical Investigation, Cohort A (ABSORB A) Everolimus Eluting Coronary Stent System Clinical Investigation
Status: COMPLETED
Conditions: Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: Bioabsorbable Everolimus Eluting Coronary Stent
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effect of Turmeric in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Turmeric test product|DIETARY_SUPPLEMENT: Turmeric comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021)
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia, Pediatric|ALL, Infants
Interventions: COMBINATION_PRODUCT: the risk-adapted choice of therapy and the use of a combination of chemotherapy with immunotherapy and hematopoietic stem cell transplantation for patients with risk factors.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study,Ceftobiprole,Healthy Volunteers,Healthy Patients With End Stage Renal Disease
Status: COMPLETED
Conditions: Staphylococcal Skin Infections|Streptococcal Infections
Interventions: DRUG: Ceftobiprole
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Bruxism in the Outcome of Subgingival Instrumentation for the Management of Stage 2 and Stage 3 Periodontitis.
Status: RECRUITING
Conditions: Periodontitis|Bruxism
Interventions: PROCEDURE: scaling and root planing|PROCEDURE: Subgingival instrumentation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cycle Control Assessment of a Combined Oral Contraceptive Containing Estetrol and a Progestin P1 or P2
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: estetrol, P 1 and placebo tablets|DRUG: estetrol, P2 and placebo tablets|DRUG: Estradiol valerate, dienogest and placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotic Use in Hernioplasty
Status: COMPLETED
Conditions: Inguinal Hernia
Interventions: DRUG: Antibiotic: cefazolin Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test the Efficacy, Safety and Pharmacokinetics of Bimekizumab in Subjects With Moderate to Severe Hidradenitis Suppurativa.
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Bimekizumab|DRUG: Adalimumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Palonosetron Hydrochloride in the Prevention of Nausea and Vomiting
Status: COMPLETED
Conditions: Neoplasms|Chemotherapy-Induced Nausea and Vomiting
Interventions: DRUG: Palonosetron Hydrochloride|DRUG: Palonosetron Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Extension for 43USSA1812
Status: COMPLETED
Conditions: Cheek|Wrinkle
Interventions: DEVICE: Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Novaloc and Locator Attachment Systems
Status: ACTIVE_NOT_RECRUITING
Conditions: Completely Edentulous Maxilla
Interventions: DEVICE: Novaloc attachment|DEVICE: Locator attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single Agent Phase II Study of Romidepsin (Depsipeptide, FK228) in the Treatment of Cutaneous T-cell Lymphoma (CTCL)
Status: COMPLETED
Conditions: Cutaneous T-cell Lymphoma
Interventions: DRUG: romidepsin (depsipeptide, FK228)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity, Safety and Immunogenicity of a Live Monovalent A/17/CALIFORNIA/66/395 (H2N2) Influenza Vaccine
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: LAIV H2N2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Behavioral Activation + Cognitive Processing Therapy for PTSD and Comorbid MDD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Major Depressive Disorder
Interventions: BEHAVIORAL: Behavioral Activation|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion
Status: RECRUITING
Conditions: Sepsis|Cardiomyopathies|Hypoperfusion|Left Ventricular Systolic Dysfunction
Interventions: DRUG: Placebos|DRUG: Dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: DS-8201a 5.4 mg/kg Q3W|DRUG: DS-8201a 6.4 mg/kg Q3W
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TTAC-0001 and Pembrolizumab Phase Ib Combination Trial in Metastatic Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: TTAC-0001 and pembrolizumab combination
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigations on Differences in Atorvastatin Metabolites Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity
Status: COMPLETED
Conditions: Myotoxicity of Atorvastatin Treatment
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase II Study of Anlotinib Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma（RCC）
Status: UNKNOWN
Conditions: Anlotinib|RCC
Interventions: DRUG: Anlotinib|DRUG: Sunitinib maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Efficacy of CardiOGoniometry (CGM) to Localise the Culprit Vessel in Mixed Vessel Disease Non-ST elevatIon Myocardial infarcTION (NSTEMI)
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DEVICE: Cardiogoniometry|DEVICE: 12-lead ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant Women
Status: COMPLETED
Conditions: Malaria|HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Efavirenz|DRUG: Zidovudine|DRUG: Lamivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of 3% Diquafosol Topical Ophthalmic Solution for Diabetic Dry Eye
Status: NOT_YET_RECRUITING
Conditions: Diabetic Eye Problems
Interventions: DRUG: 3% Diquafosol tetrasodium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase 2 Study of Indomethacin Capsules to Treat Dental Pain
Status: COMPLETED
Conditions: Dental Pain
Interventions: DRUG: Celecoxib 400 mg|DRUG: Placebo|DRUG: Indomethacin Test (lower dose)|DRUG: Indomethacin Test (upper dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Dexmedetomidine Hydrochloride Nasal Spray in Preoperative Sedation of Children
Status: COMPLETED
Conditions: Preoperative Sedation of Children
Interventions: DRUG: Dexmedetomidine Hydrochloride Nasal Spray|DRUG: Dexmedetomidine hydrochloride nasal spray blank preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Ease of Endotracheal Intubation Using C Blade and D Blade of CMAC Videolaryngoscope in Patients Undergoing Elective Cervical Spine Surgery
Status: COMPLETED
Conditions: Cervical Spine Instability
Interventions: PROCEDURE: Intubation with C blade|PROCEDURE: Intubation with D blade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Neuroblastoma|Immunodeficiencies|Anemia
Interventions: DRUG: Alemtuzumab|RADIATION: Total Body Irradiation|DRUG: Melphalan|DRUG: Busulfan|DRUG: Phenytoin|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Horse Antithymocyte Globulin|DRUG: Rabbit Antithymocyte Globulin|DRUG: Thiotepa
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: CHF 1535 100/6 µg pMDI plus Symbicort® Turbohaler® Placebo|DRUG: Symbicort® Turbohaler® plus CHF 1535 pMDI Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Spinal Anesthesia on Hemodynamics
Status: COMPLETED
Conditions: Anesthesia, Spinal
Interventions: OTHER: 7.5 mg hyperbaric bupivacaine|OTHER: 5 mg hyperbaric bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Reduction of EArly mortaLITY in HIV-infected Adults and Children Starting Antiretroviral Therapy
Status: COMPLETED
Conditions: Human Immunodeficiency Virus
Interventions: DRUG: Raltegravir|DRUG: Fluconazole|DRUG: Azithromycin|DRUG: Albendazole|DRUG: Isoniazid|DIETARY_SUPPLEMENT: Ready to Use Supplementary Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Surgical Sequences "Cataract Surgery Then Vitrectomy" Versus "Vitrectomy Then Cataract Surgery" Under Local-regional Anesthesia
Status: COMPLETED
Conditions: Cataract|Vitreous Disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aminolevulinic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment and Management of Pain, Agitation, Delirium and Sleep Deprivation (PADS) in ICU by PADS Protocol, Thailand
Status: COMPLETED
Conditions: Pain|Agitation on Recovery From Sedation|Delirium
Interventions: OTHER: PADS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Inferiority,Combination Formoterol/FluticasonexAlenia®Formoterol/Budesonide for Asthma in Brazil
Status: NOT_YET_RECRUITING
Conditions: Moderate Asthma
Interventions: DRUG: Administration of investigation drug|DRUG: Administration of comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 16α-18F-fluor-17β-estradiol PET/CT for Visualisation of Estrogen Receptor Positive Liver Metastases From Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: 16α-18F-fluor-17β-estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: BRAND'S® Essence of Chicken in the Promotion of Resilience and Resistance to Stress-associated Cognitive Inhibition
Status: UNKNOWN
Conditions: Stress Associated Cognitive Inhibition|Essence of Chicken|Cognition|Immunity|Metabolism
Interventions: DIETARY_SUPPLEMENT: Chicken Essence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Foley and T-Control® Catheter in Patients With Long-term Catheterization
Status: RECRUITING
Conditions: Catheter-Associated Urinary Tract Infection|Catheter Related Complication|Quality of Life
Interventions: DEVICE: Foley catheter|DEVICE: T-Control catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Intensive Locomotor Treadmill Training on Gross Motor Function in Young Children With Neuromotor Impairment
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: treadmill training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Safety and Efficacy Study of PRT060128, a Novel Intravenous and Oral P2Y12 Inhibitor, in Non-Urgent PCI
Status: COMPLETED
Conditions: Percutaneous Coronary Intervention
Interventions: DRUG: clopidogrel|DRUG: PRT060128
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Multicenter, Open-label, Parallel-group, 12-week Study to Assess the Efficacy and Safety of Switching From Tiotropium to QVA149 (Indacaterol Maleate/Glycopyrronium Bromide) in Symptomatic Mild to Moderate COPD Patients
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Indacaterol and glycopyrronium (QVA149)|DRUG: Tiotropium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Music on Neonatal Stress, Mother's Breastfeeding Success and Comfort
Status: NOT_YET_RECRUITING
Conditions: Music|Breastfeeding|Newborn|Mother
Interventions: BEHAVIORAL: white noise music|BEHAVIORAL: lullaby music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Oral semaglutide|DRUG: Placebo (semaglutide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QOL Improvement After Cardioversion of Persistent AF (QOL-CAFRCT)
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Electrical cardioversion|OTHER: Sham electrical cardioversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Instrument Assisted Soft Tissue Mobilization in Addition to Conventional Physiotherapy in Knee Arthrofibrosis
Status: RECRUITING
Conditions: Knee Arthrofibrosis
Interventions: PROCEDURE: Instrument Assisted Soft tissue mobilization|PROCEDURE: Conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glenzocimab in Anterior Stroke With Large Ischemic Core Eligible for Endovascular Therapy
Status: NOT_YET_RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: DRUG: glenzocimab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Aclidinium Bromide Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DRUG: Aclidinium bromide 400 μg bid|DRUG: Tiotropium 18 μg once-daily|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Airflow Obstruction, Chronic|Chronic Obstructive Airway Disease|Chronic Obstructive Lung Disease
Interventions: DEVICE: NIOV System|DEVICE: Standard Oxygen Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Open, Controlled, Phase III Clinical Study to Evaluate the Efficacy and Safety of Cipepofol Injection for General Anesthesia in Pediatric Patients Undergoing Elective Surgery
Status: RECRUITING
Conditions: Anesthesia
Interventions: DRUG: Cipepofol|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of NP001 in Subjects With Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: NP001|DRUG: NP001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of PICC Improving HBA1C and Knowledge in Diabetes Mellitus Education
Status: COMPLETED
Conditions: Diabetes Mellitus|Type2 Diabetes
Interventions: BEHAVIORAL: PICC Program|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Study of JZP-458 (RC-P) in Patients With Acute Lymphoblastic Leukemia (ALL)/Lymphoblastic Lymphoma (LBL)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Lymphoblastic Leukemia
Interventions: DRUG: IM JZP-458|DRUG: IV JZP-458
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease
Status: RECRUITING
Conditions: Sickle Cell Disease|Diffuse Myocardial Fibrosis
Interventions: DRUG: Losartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sling vs Botox for Mixed Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Urinary Incontinence, Urge
Interventions: DRUG: Botox® injection|DEVICE: Mid-urethral sling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Cancer
Interventions: DRUG: Pazopanib|DRUG: Bevacizumab|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immune Response of an Investigational Vaccine for the Prevention of RSV (Respiratory Syncytial Virus) and (hMPV) Human Metapneumovirus Infection in Participants Aged 60 to 75 Years
Status: NOT_YET_RECRUITING
Conditions: RSV Infection|hMPV
Interventions: BIOLOGICAL: RSV/hMPV vaccine dose A1|BIOLOGICAL: RSV/hMPV vaccine dose A2|BIOLOGICAL: RSV/hMPV vaccine dose A3|BIOLOGICAL: RSV/hMPV vaccine dose B1|BIOLOGICAL: RSV/hMPV vaccine dose B2|BIOLOGICAL: RSV/hMPV vaccine dose B3|BIOLOGICAL: RSV/hMPV vaccine dose C1|BIOLOGICAL: RSV/hMPV vaccine dose C2|BIOLOGICAL: RSV/hMPV vaccine dose C3|BIOLOGICAL: RSV/hMPV vaccine dose 1|BIOLOGICAL: RSV/hMPV vaccine dose 2|BIOLOGICAL: RSV/hMPV vaccine dose 3|BIOLOGICAL: Monovalent RSV Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Frontal Lobe Oxyhemoglobin Levels in Patients With Lower Extremity Burns Assessed Using a fNIRS
Status: COMPLETED
Conditions: Walking
Interventions: DIAGNOSTIC_TEST: Functional near-infrared spectroscopy (fNIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
Status: COMPLETED
Conditions: Health Behavior|Colorectal Cancer|Influenza|COVID-19|Vaccine Hesitancy|Vaccine-Preventable Diseases|Healthcare Patient Acceptance
Interventions: BEHAVIORAL: Financial incentive for colorectal cancer screening|BEHAVIORAL: Financial incentive for flu shot|BEHAVIORAL: Financial incentive for COVID-19 shot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study of Efficacy and Safety of Secukinumab in Patients With Non-radiographic Axial Spondyloarthritis
Status: COMPLETED
Conditions: Non-radiographic Spondyloarthritis
Interventions: DRUG: Secukinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT