pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Study on Preoperative Versus Postoperative Venous Thromboprophylaxis in Patients Undergoing Major Colorectal Surgery
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: " Acute Brain Changes After Repetitive Headers in Soccer and the Effects of a Protective Device "
Status: COMPLETED
Conditions: Traumatic Brain Injury|Concussion, Brain
Interventions: PROCEDURE: Heading series|DEVICE: Magnetic Resonance Imaging (MRI)|OTHER: Cognitive computerized assessment|PROCEDURE: Electrophysiological records|DEVICE: Dynamometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of SHR3162 Combined With Apatinib Mesylate Tablets or SHR3162 Monotherapy in Patients With Metastatic Castration Resistant Prostate Cancer
Status: UNKNOWN
Conditions: Metastatic Castration Resistant Prostate Cancer
Interventions: DRUG: Fluzoparib|DRUG: Enzalutamide OR abiraterone acetate With Prednisone Acetate Tablets|DRUG: Fluzoparib Combined With Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effects of Krill Oil on Fasting Serum Triglycerides
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Krill Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long-term Safety of Dasatinib in Patients With Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Dasatinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Treatment for Patients With Cancer of the Eye -Retinoblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinoblastoma|Retinal Neoplasm
Interventions: PROCEDURE: Enucleation|DRUG: Vincristine, Carboplatin|PROCEDURE: Focal Therapies|RADIATION: External Beam Radiation|DRUG: Vincristine and Topotecan|DRUG: Vincristine + Carboplatin + Etoposide|DRUG: vincristine, cyclophosphamide, and doxorubicin|DRUG: Vincristine, Carboplatin and Etoposide|PROCEDURE: Periocular carboplatin|OTHER: G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: FES Therapy|DEVICE: FES Therapy|OTHER: Conventional Occupational Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant
Status: WITHDRAWN
Conditions: Pulmonary Disease, Chronic Obstructive|Emphysema
Interventions: DEVICE: Silicone Stent Airway Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ultrasound Imaging-based Measurement of Intra-osseous Vascular Response
Status: COMPLETED
Conditions: Blood Circulation Disorder|Bone Diseases, Metabolic
Interventions: DEVICE: ultrasound imaging at the forearm and at the tibia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Study of GlySure Continuous Intra-vascular Glucose Monitoring and Intermittent Monitoring in Medical ICU
Status: UNKNOWN
Conditions: Blood Glucose Monitoring in Medical ICU
Interventions: DEVICE: GlySure Intravascular Continuous glucose monitoring sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multiple Ascending Dose Study of COR388
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: COR388|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation
Status: RECRUITING
Conditions: Symptomatic Severe Aortic Stenosis
Interventions: DEVICE: Navitor Transcatheter Aortic Valve and FlexNav Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia
Status: COMPLETED
Conditions: Gastroparesis|Dyspepsia
Interventions: DRUG: Cannabidiol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Investigational Lubricant Eye Drop on Lipid Layer Thickness
Status: COMPLETED
Conditions: Dry Eye
Interventions: OTHER: ORB Ocular Emulsion|OTHER: SootheXP Emollient (Lubricant) Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Biomarkers for the Response to Anti-VEGF (Vascular Endothelial Growth Factor).Treatment in Wet Age-related Macular Degeneration (Wet ARMD)
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DEVICE: Genotype analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: DNA Analysis of Tumor Tissue Samples From Patients With Human Papilloma Virus-Associated Cancer of the Oropharynx
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polyacrylamide gel electrophoresis|GENETIC: polymerase chain reaction|GENETIC: protein expression analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: flow cytometry|OTHER: immunoenzyme technique|OTHER: immunologic technique|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer
Status: COMPLETED
Conditions: Lung Neoplasms|Thoracic Surgery|Carcinoma, Non-Small-Cell Lung|Lung Diseases|Carcinoma, Bronchogenic|Thoracic Neoplasm
Interventions: PROCEDURE: Subxiphoid uniportal VATS|PROCEDURE: Intercostal uniportal VATS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study
Status: COMPLETED
Conditions: Intrinsic Aging of Skin|Solar Elastosis
Interventions: DRUG: Right lateral orbital injection of Botox Cosmetic or Dysport|DRUG: Left lateral orbital injection of Botox Cosmetic or Dysport
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Intravenous Immunoglobulin (IVIg) for Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Intravenous Immunoglobulin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Electrocochleography Along Cochlear Implant Auditory Rehabilitation
Status: WITHDRAWN
Conditions: Cochlear Prosthesis Implantation
Interventions: PROCEDURE: Electrocochleography|OTHER: Pure Tone Audiometry|OTHER: Speech audiometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Huashi Baidu Granule in the Treatment of Pediatric Patients With Mild Coronavirus Disease 2019
Status: COMPLETED
Conditions: Coronavirus Disease 2019
Interventions: DRUG: Huashi Baidu granule|DRUG: compound pholcodine oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Fumaric Acid Esters (Fumaderm®) in the Treatment of Patients With Cutaneous Lupus Erythematosus
Status: COMPLETED
Conditions: Lupus Erythematosus, Cutaneous
Interventions: DRUG: Fumaric acid esters
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Risperidone and Trazodone Monotherapy and Combination Therapy in Critically Ill Patients With Delirium
Status: WITHDRAWN
Conditions: Delirium|Agitation
Interventions: DRUG: Risperidone|DRUG: Trazodone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Body Weight, Sleep, and Heart Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiovascular Risk Factor|Circadian Dysregulation|Obesity
Interventions: RADIATION: PET Imaging|BEHAVIORAL: Circadian Study Protocol|DRUG: 11C-Meta-Hydroxyephedrine (mHED)|DRUG: 11C-CGP12177|DRUG: O15-water
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Plasma Amino Acid Response to Whey Protein Ingestion Following 28-days of Probiotic Supplementation
Status: COMPLETED
Conditions: Focus of Study is Amino Acid Appearace in Blood
Interventions: DIETARY_SUPPLEMENT: Bacillus subtilis DE111|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nanocrystalline Hydroxyapatite Bone Substitute for Treating Periodontal Intrabony Defects
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: open flap debridement|PROCEDURE: n-HA bone graft
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Optimal Neuroprotection of neu2000 in Ischemic Stroke With Endovascular reCanalizion (SONIC)
Status: UNKNOWN
Conditions: Ischemic Stroke
Interventions: DRUG: Neu2000KWL High-does group|DRUG: Neu2000KWL Low-does group|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants with Advanced or Metastatic Solid Tumors with KRAS Mutations or Amplification
Status: NOT_YET_RECRUITING
Conditions: Metastatic Solid Tumors|Advanced Non-squamous Non-small-cell Lung Cancer|Advanced Colorectal Cancer|Advanced Pancreatic Ductal Adenocarcinoma|Advanced Gastric Cancer|Advanced Gastroesophageal Junction Cancer|Advanced Esophageal Adenocarcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Evidence-Based Focal Cryotherapy Protocol for Focal Ablation of Intermediate Risk Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: OTHER: Focal Cryoablation|OTHER: Standard of Care|OTHER: Quality-of-life Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients
Status: UNKNOWN
Conditions: Multiple Myeloma|Plasma Cell Leukemia|Extramedullary Plasmacytoma|Loss of Chromosome 17p|t(14;16)|t(4;14)|T(14;20)|1Q21 Amplification|Complex Karyotype
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation x 1 or x 2|DRUG: Melphalan Given IV|DRUG: Fludarabine Injection|DRUG: PI and dexamethasone as maintenance therapy|DRUG: PI+IMids+Dexamethasone as Consolidated Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Radiofrequency Treatments for the Treatment of Trigeminal Neuralgia.
Status: COMPLETED
Conditions: Trigeminal Neuralgia
Interventions: PROCEDURE: radiofrequency of gasserian ganglion|PROCEDURE: radiofrequency of the peripheral trigeminal branches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of BCD-063 and Copaxone-Teva in Patients With Relapsing-Remitting Multiple Sclerosis
Status: COMPLETED
Conditions: Relapsing-remitting Multiple Sclerosis
Interventions: DRUG: BCD-063|DRUG: Copaxone-Teva|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Transvenous Pacing Wire During Minimally Invasive Port Access Aortic Valve Surgery
Status: TERMINATED
Conditions: Aortic Valve Disease
Interventions: PROCEDURE: Minimally Invasive Aortic Valve|PROCEDURE: Minimally Invasive Aortic Valve Surgery|DEVICE: Manipulation in OR surgical technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Apneic Intubation Critically Ill Children
Status: UNKNOWN
Conditions: Airway Management
Interventions: PROCEDURE: Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Whether BLI-489 Can be Safely Tolerated by Healthy Subjects Given Multiple Doses
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BLI-489|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Intake of Pyrus Pyrifolia Var. Culta(Makino) NaKai Peel Extract on Body Fat and Blood Lipid.
Status: UNKNOWN
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Pyrus pyrifolia var. culta(Makino) NaKai peel extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Safety and Efficacy of Botulinum Toxin Type A (BOTOX®) to Treat Urinary Incontinence Due to Neurogenic Detrusor Overactivity or Overactive Bladder in Korea
Status: COMPLETED
Conditions: Urinary Incontinence|Urinary Bladder, Overactive
Interventions: BIOLOGICAL: botulinum toxin Type A
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Nicotinamide in Treatment of DLE
Status: COMPLETED
Conditions: Discoid Lupus Erythematosus
Interventions: DRUG: Nicotinamide Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Beta-alanine Supplementation and CrossFit Performance
Status: COMPLETED
Conditions: Exercise-Induced Lactic Acidemia
Interventions: DIETARY_SUPPLEMENT: Beta-alanine|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Tissue in the Treatment of Systemic Sclerosis Digital Ulcers
Status: UNKNOWN
Conditions: Systemic Sclerosis|Digital Ulcer
Interventions: PROCEDURE: Autologous fat grafting|PROCEDURE: Sham procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cocoa Supplementation in Training Athletes Microbiota and Metabolome
Status: COMPLETED
Conditions: Healthy Athletes
Interventions: DIETARY_SUPPLEMENT: cocoa|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Early Mobilisation After Surgery in Patients With Elbow Fracture-dislocation
Status: UNKNOWN
Conditions: Early Mobilization|Elbow Stiffnes|Elbow Fracture
Interventions: OTHER: Experimental early mobilisation|OTHER: Aktive comparator standrad treatmnet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: COgnitive and Physical Exercise (COPE) Prehabilitation Pilot Feasibility Study
Status: COMPLETED
Conditions: Cognitive Impairment|Physical Impairment|Postoperative Complications
Interventions: BEHAVIORAL: Cognitive and physical prehabilitation|OTHER: Active attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib
Status: RECRUITING
Conditions: Early-stage Breast Cancer|HER2 Positive Breast Cancer|Hormone Receptor Positive
Interventions: DRUG: Neratinib|DRUG: Loperamide|DRUG: Colesevelam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Serum-Free Thymus Transplantation in DiGeorge Anomaly
Status: TERMINATED
Conditions: DiGeorge Anomaly
Interventions: BIOLOGICAL: Serum Free Thymus Transplantation with Immunosuppression|OTHER: Serum Free Thymus Transplantation without immunosuppression
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Low-Dose Theophylline for the Management of Biomass-Associated COPD
Status: COMPLETED
Conditions: COPD|COPD Exacerbation|COPD Exacerbation Acute|Pollution Related Respiratory Disorder|Pollution; Exposure
Interventions: DRUG: Theophylline ER|DRUG: Placebo oral tablet|OTHER: Standard of Care Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Finerenone in IgA Nephropathy
Status: NOT_YET_RECRUITING
Conditions: IgA Nephropathy
Interventions: DRUG: Finerenone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cequa Treatment on Accuracy of Pre-operative Biometry & Higher Order Aberrations in Dry Eye Patients Undergoing Cataract Surgery
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Cequa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pemetrexed Disodium and Cisplatin Before or After Surgery in Treating Patients With Stage IB or Stage II Non-Small Cell Lung Cancer That Can be Removed by Surgery
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: pemetrexed disodium|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: neoadjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERAS in Totally Laparoscopic Total Gastrectomy for Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer|ERAS|Laparoscopic Gastrectomy
Interventions: OTHER: ERAS protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation
Status: COMPLETED
Conditions: Mitral Valve Insufficiency|Coronary Artery Disease
Interventions: PROCEDURE: Mitral Valve Repair|PROCEDURE: CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Belimumab|DRUG: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Sevoflurane and Propofol for Maintenance of Sedation During ERCP
Status: COMPLETED
Conditions: Sedation Complication
Interventions: DRUG: Propofol 1 % Injectable Suspension|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-Guided Aspiration of PTA vs Conventional Landmark Technique - a RCT
Status: UNKNOWN
Conditions: Peritonsillar Abscess
Interventions: DIAGNOSTIC_TEST: Intraoral ultrasound|PROCEDURE: The landmark technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lumigan® in Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: bimatoprost 0.01%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Palonosetron and Ramosetron for Preventing Patient-controlled Analgesia Related Nausea and Vomiting Following Spine Surgery; Association With ABCB1 Polymorphism
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Ramosetron|DRUG: Palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: DIAgnosing GDM usiNg Oral Sugar InStead
Status: RECRUITING
Conditions: Diabetes, Gestational
Interventions: DIETARY_SUPPLEMENT: Dex4/ dextrose|DIETARY_SUPPLEMENT: Glucose beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of MTRX1011A in Patients With Rheumatoid Arthritis
Status: TERMINATED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: MTRX1011A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acetylsalicylic Acid (ASA) + Paracetamol + Caffeine Combination Compared With ASA + Paracetamol as Well as ASA, Paracetamol, and Caffeine in Headache Patients
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: DRUG: Low dose ASA|DRUG: High dose ASA|DRUG: Low dose paracetamol|DRUG: High dose paracetamol|DRUG: Caffeine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Mirogabalin for Total Hip Arthroplasty
Status: RECRUITING
Conditions: Hip Osteoarthritis
Interventions: DRUG: Arm I (mirogabalin group)|DRUG: Arm II (placebo group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Neuromodulation for Diabetic Gastroparesis
Status: RECRUITING
Conditions: Diabetic Gastroparesis
Interventions: DEVICE: 2400 ThorS-MagNT Stimulations at 1Hz|DEVICE: 2400 ThorS-MagNT Stimulations at 10Hz|DEVICE: Sham Stimulations
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery
Status: COMPLETED
Conditions: Thromboembolism|Hemodialysis
Interventions: DRUG: Fragmin (dalteparin)|DRUG: Innohep (tinzaparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Optimization of Bioavailability From Iron Supplements: Study 1
Status: COMPLETED
Conditions: Iron Deficiency|Anemia|Iron Deficiency Anemia
Interventions: DIETARY_SUPPLEMENT: Daily administration of 60 mg iron in form of ferrous sulphate capsules for 14 consecutive days|DIETARY_SUPPLEMENT: Administrations of 60 mg iron in form of ferrous sulphate capsules on every second day for 28 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Acceptance-Based Behavior Therapy (ABBT)|BEHAVIORAL: Enhanced-Treatment-as-Usual (ETAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training for Cervicogenic Dysphagia
Status: COMPLETED
Conditions: Dysphagia, Esophageal
Interventions: OTHER: Structured exercise training program + The swallow resistance exercise program.|OTHER: Only the swallow resistance exercise program.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lazertinib Real-world Observational Study of in Pre-treated EGFR T790M Mutant With Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Metastatic Lung Non-Small Cell Carcinoma|EGFR T790M
Interventions: DRUG: Lazertinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dose, Safety, Tolerability and Immunogenicity of a Stabilized Prefusion RSV F Subunit Protein Vaccine, VRC-RSVRGP084-00-VP (DS-Cav1), Alone or With Alum Adjuvant, in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus
Interventions: BIOLOGICAL: VRC-RSVRGP084-00-VP|OTHER: Aluminum Hydroxide Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Saxagliptin, 5 mg + insulin|DRUG: Placebo + insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Response Relationship of Oxytocin on Irritability in Youths
Status: TERMINATED
Conditions: Irritable Mood
Interventions: PROCEDURE: Functional MRI (fMRI)|DRUG: Oxytocin Intranasal Spray 8 International Unit (8IU)|DRUG: Oxytocin intranasal spray 24 International Unit (24IU)|DRUG: Oxytocin intranasal spray 48 International Unit (48IU)|DRUG: Oxytocin intranasal spray 80 International Unit (80IU)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Compare the Clinical Application of 18F-LNC1007 Injection PET/CT and 18F-FDG PET/CT
Status: NOT_YET_RECRUITING
Conditions: Tumour
Interventions: OTHER: 18F-LNC1007（18F-FAPI-RGD） PET/CT和18F-FDG PET/CT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Compare Ventral Incisional Hernia by Laparoscopic vs Open Repair With Mesh
Status: COMPLETED
Conditions: Hernia, Ventral
Interventions: PROCEDURE: Open mesh repair of ventral incisional hernia|PROCEDURE: Laparoscopic mesh repair of ventral incisional hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Corticotrophin (ACTH) in Combination With Methotrexate in Newly Diagnosed Rheumatoid Arthritis Patients
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: corticotrophin 80 units
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femto-flap Versus SBK Flap,Predictability and Variability
Status: COMPLETED
Conditions: Refractive Errors|Refractive Surgery
Interventions: PROCEDURE: Visumax Femto-flap|PROCEDURE: Sub Bowman's keratomileusis (SBK)-flap
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Anakinra to Reduce Secondary Brain Damage After Spontaneous Haemorrhagic Stroke
Status: RECRUITING
Conditions: Intracerebral Hemorrhage
Interventions: DRUG: Anakinra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Galactooligosaccharides on Incidence of Atopic Manifestations in Infants
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: OTHER: galactooligosaccharide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Trial of PD 0332991 Plus Bortezomib in Patients With Relapsed Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: PD 0332991|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Stroke Patients and Their Caregiver Benefit From Additive Mindfulness Training
Status: UNKNOWN
Conditions: Stroke|Relatives|Motor Disorder|Attention Deficit|Quality of Life
Interventions: OTHER: Mindfulness, MBSR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Neuromuscular Block on Surgical Condition During Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: sugammadex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: UC-961 (Cirmtuzumab) in Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: cirmtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional and Anti-infective Interventions for Malnutrition in Pregnancy (Beleuman Welbodi)
Status: COMPLETED
Conditions: Pregnancy|Malnutrition in Pregnancy|Nutrition Disorders|Stunting
Interventions: DIETARY_SUPPLEMENT: Ready-to-use-supplementary food|DIETARY_SUPPLEMENT: Corn-soy-blend|DRUG: Monthly intermittent preventive treatment of malaria during pregnancy (IPTp)|DRUG: Standard intermittent preventive treatment of malaria during pregnancy (IPTp)|OTHER: Insecticide-treated mosquito net|DRUG: Azithromycin|DRUG: Albendazole|COMBINATION_PRODUCT: Bacterial vaginosis testing and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics)
Status: COMPLETED
Conditions: Drug Interaction Potential
Interventions: DRUG: Tolbutamide|DRUG: Midazolam|DRUG: Pexidartinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: P4 (Pregabalin for Peripheral Posttraumatic Pain)
Status: COMPLETED
Conditions: Neuralgia
Interventions: DRUG: pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenetic Dosing of Warfarin
Status: COMPLETED
Conditions: Stroke|Venous Thrombosis|Atrial Fibrillation|Atrial Flutter
Interventions: BEHAVIORAL: Standard of care dosing for warfarin|GENETIC: Genotype-guided dosingTaiwan algorithm for warfarin|GENETIC: Genotype-guided dosing IWPC algorithm for warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Masitinib in Combination With Gemcitabine in Advanced/Metastatic Epithelial Ovarian Cancer Patients
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Masitinib|DRUG: Gemcitabine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-thoracotomy Pain Management With Active External Warming and Ice Application
Status: COMPLETED
Conditions: Post Operative Pain|Pain, Acute|Thoracic Injury
Interventions: OTHER: Active external warming|OTHER: Ice application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Efficacy of Methadyl Acetate (LAAM) and Contingency Management Procedures for Treating Dual Opioid and Cocaine Abuse - 1
Status: COMPLETED
Conditions: Behavior Therapy|Cocaine|Contingency Management|Heroin Dependence|LAAM|Opioid Dependence|Substance-Related Disorders|Alcohol & Drug Use
Interventions: BEHAVIORAL: LAAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Difference in Heat Transport Characteristics of the Heart and Lung Meridians
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIAGNOSTIC_TEST: Infrared thermography|PROCEDURE: Moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Neuroprotective Effect of PEG-GCSF in the Traumatic Optic Neuropathy
Status: RECRUITING
Conditions: Traumatic Optic Neuropathy
Interventions: DRUG: Neulasta® (pegfilgrastim)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temsirolimus and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
Status: TERMINATED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Blastic Phase Chronic Myelogenous Leukemia|Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Chronic Phase Chronic Myelogenous Leukemia|Relapsing Chronic Myelogenous Leukemia
Interventions: DRUG: imatinib mesylate|DRUG: temsirolimus|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation Versus Thoracoscopic Surgical Ablation in Long Standing Persistent Atrial Fibrillation (CASA-AF)
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Thoracoscopic Surgical ablation|PROCEDURE: Catheter ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort
Status: UNKNOWN
Conditions: Aortic Valve Stenosis
Interventions: DIAGNOSTIC_TEST: 18F-FDG PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: OTHER: Observation of Ocrelizumab as Treatment in RRMS Patients
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Safety and Pharmacology of DNIB0600A in Participants With Platinum-Sensitive Ovarian Cancer or Non-Squamous Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Squamous Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab|DRUG: Carboplatin|DRUG: DNIB0600A
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Age Differences in Influenza and Herpes Zoster Vaccine Responses (INFLUENZA-SHINGRIX)
Status: COMPLETED
Conditions: Influenza|Herpes Zoster
Interventions: BIOLOGICAL: Herpes zoster vaccination (Shingrix, GSK)|BIOLOGICAL: Influenza Vaccine (Fluarix Tetra Northern Hemisphere 2021 or 2022, GSK)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC)
Status: TERMINATED
Conditions: Prostatic Cancer, Castration-Resistant
Interventions: DRUG: Darolutamide (Nubeqa, BAY1841788)|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis
Status: UNKNOWN
Conditions: Joint Diseases|Knee|Therapeutics|Magnetic Resonance Imaging
Interventions: DRUG: Botulinum Toxin Type A 100U|DRUG: Botulinum Toxin Type A 200U|DRUG: Triamcinolone Hexacetonide Inj Susp 20 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder
Status: UNKNOWN
Conditions: Propionibacterium Infection
Interventions: DRUG: a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol|DRUG: Iodine scrub and ChloraPrep alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transcriptome Analysis of Human Bone Regeneration After Using an Anorganic Bovine Bone Graft With or Without a Combination of Polynucleotides and Hyaluronic Acid
Status: RECRUITING
Conditions: Sinus Floor Augmentation
Interventions: PROCEDURE: Maxillary sinus floor augmentation|PROCEDURE: Maxillary sinus floor augmentation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of PBK-1801 After Single Oral Administration in Healthy Korean Women
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: PBK-1801|DRUG: PBK-1801|DRUG: PBK-1801
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact on Swallowing of Non Invasive Ventilation
Status: COMPLETED
Conditions: Neuromuscular Disorder|Respiratory Failure|Swallowing|Mechanical Ventilation
Interventions: OTHER: Spontaneous breathing|DEVICE: Elysée 150®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Placebo Controlled Phase IV Study to Compare the Efficacy and Safety of a Single Dose of Oral Talcid, a Single Dose of Oral Famotidine and a Single Dose of Placebo in Patients With Acute Heartburn Episodes
Status: COMPLETED
Conditions: Heartburn
Interventions: DRUG: Talcid (Hydrotalcite, BAY4516H)|DRUG: Famotidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dairy- and Berry-based Snacks on Nutritional and Functional Status and Quality of Life in Older People
Status: COMPLETED
Conditions: Nutrition Disorders in Old Age
Interventions: DIETARY_SUPPLEMENT: Dairy- and berry-based snacks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Renal Denervation in Treatment Resistant Hypertension
Status: TERMINATED
Conditions: Hypertension
Interventions: PROCEDURE: Ablation of the renal arteries|PROCEDURE: Renal angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Stress-CMR Using Regadenoson and GE-267 in Adult Patients With Known or Suspected Coronary Artery Disease
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DIAGNOSTIC_TEST: Cardiac MRI using Regadenoson and GE-267
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Effect of Pure Canterbury Stage 1 Infant Formula Milk Powder on the Growth of Infant 0-6 Months of Age
Status: COMPLETED
Conditions: Growth Acceleration
Interventions: OTHER: Oral consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reliving Chronic Non-malignant Pain of Elderly Individuals Using Aromatic Hand Massage
Status: COMPLETED
Conditions: Non-malignant Chronic Pain
Interventions: OTHER: massage with lavender essential oil mixed in a carrier oil|OTHER: massage with odourless baby oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphatic System Neoplasm|Recurrent Ependymoma|Recurrent Ewing Sarcoma|Recurrent Hepatoblastoma|Recurrent Histiocytic and Dendritic Cell Neoplasm|Recurrent Langerhans Cell Histiocytosis|Recurrent Lymphoma|Recurrent Malignant Germ Cell Tumor|Recurrent Malignant Glioma|Recurrent Malignant Solid Neoplasm|Recurrent Medulloblastoma|Recurrent Neuroblastoma|Recurrent Non-Hodgkin Lymphoma|Recurrent Osteosarcoma|Recurrent Peripheral Primitive Neuroectodermal Tumor|Recurrent Rhabdoid Tumor|Recurrent Rhabdomyosarcoma|Recurrent Soft Tissue Sarcoma|Recurrent WHO Grade 2 Glioma|Refractory Ependymoma|Refractory Ewing Sarcoma|Refractory Hepatoblastoma|Refractory Histiocytic and Dendritic Cell Neoplasm|Refractory Langerhans Cell Histiocytosis|Refractory Lymphoma|Refractory Malignant Germ Cell Tumor|Refractory Malignant Glioma|Refractory Malignant Solid Neoplasm|Refractory Medulloblastoma|Refractory Neuroblastoma|Refractory Non-Hodgkin Lymphoma|Refractory Osteosarcoma|Refractory Peripheral Primitive Neuroectodermal Tumor|Refractory Rhabdoid Tumor|Refractory Rhabdomyosarcoma|Refractory Soft Tissue Sarcoma|Refractory WHO Grade 2 Glioma|Wilms Tumor
Interventions: PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Positron Emission Tomography|PROCEDURE: Radionuclide Imaging|DRUG: Selpercatinib|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Free Living Food Waste Management and Diet Quality Improvement Using Smart Intervention and Food Image Application
Status: ACTIVE_NOT_RECRUITING
Conditions: Diet, Healthy
Interventions: OTHER: Smart Intervention for Food Waste Management and Replacing current diet with Fruits and Vegetables|OTHER: Smart Intervention for Stress Managment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Antiviral Activity and Safety Endpoints for the Treatment of Besifovir 150mg Compared to Tenofovir 300mg in Chronic Hepatitis B Patients Who Have Resistance to Nucleoside Analogues
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Besifovir 150mg|DRUG: Tenofovir 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone as an Adjuvant in Supraclavicular Block
Status: UNKNOWN
Conditions: Dexamethasone Efficacy as an Adjuvant in Supraclavicular Block
Interventions: DRUG: Dexamethasone injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: LBH589, Paclitaxel, Carboplatin +/- Bevacizumab for Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: LBH589, Paclitaxel, Carboplatin, Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT