pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Prospective Comparison of Cirrus Versus Stratus Ocular Coherence Tomography for Different Retinal Pathology.
Status: COMPLETED
Conditions: Retinal Pathology
Interventions: DEVICE: Optical coherance tomography ( Cirrus; Stratus)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety Study of an Adjuvanted Candidate Influenza Vaccine to Prevent Influenza Disease in the Elderly Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: influenza vaccine Fluarix, Adjuvanted Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neuromodulation of Inflammation and Vascular Function in Systolic Heart Failure
Status: TERMINATED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DEVICE: TVS|DEVICE: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Glycaemic Control With Insulin Detemir as an add-on to Current Oral Anti-diabetic Drug Treatment in Subjects With Type 2 Diabetes in Korea
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Soft and Hard Tissues Evaluation Around Immediately Placed New Implant Design
Status: COMPLETED
Conditions: Peri-implant Mucositis|Dental Implant Failed
Interventions: PROCEDURE: platform switching|PROCEDURE: platform amtching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Tolerability Study of BIBF 1120 as Intravenous Infusion and Absolute Bioavailability of BIBF 1120 as Soft Gelatine Capsule in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBF 1120 soft gelatine capsule|DRUG: BIBF 1120 intravenous solution|DRUG: Placebo ampoule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart Failure
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: Enalapril|DRUG: Aliskiren
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Icotinib Combined With SBRT for Patients With Metastatic Non-squamous NSCLC With EGFR Mutation
Status: UNKNOWN
Conditions: Lung Cancer Stage IV
Interventions: DRUG: Icotinib|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' 10-valent Pneumococcal Conjugate Vaccine
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Synflorix|BIOLOGICAL: Infanrix IPV/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of New Technique Taping and Placebo Taping on Patellofemoral Pain Syndrome: A Randomised Controlled Study
Status: COMPLETED
Conditions: Patello Femoral Syndrome
Interventions: OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Low Dose Oral Vitamin K Improve International Normalized Ratio (INR) Stability?
Status: COMPLETED
Conditions: Coagulation|Bleeding|Thrombosis
Interventions: DRUG: Phytonadione (Vitamin K1)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dual Use Approach Bias Training for Nicotine Addiction
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Smoking|Electronic Cigarette Use|Substance Use
Interventions: OTHER: CC+ECIG Condition|OTHER: CC Condition|OTHER: Sham Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidemiology of the Nasal Flora at the Reference Center for Cystic Fibrosis of Queen Fabiola Children's University Hospital.
Status: UNKNOWN
Conditions: Cystic Fibrosis
Interventions: PROCEDURE: nasopharyngeal swab versus nasal wash
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin|HIV Infections
Interventions: DRUG: Bleomycin sulfate|DRUG: Vincristine sulfate|DRUG: Doxorubicin hydrochloride|DRUG: Cyclophosphamide|DRUG: Allopurinol|DRUG: Methotrexate|DRUG: Cytarabine|DRUG: Leucovorin calcium|DRUG: Sargramostim|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Online Perceptual Modules and Spaced Learning, a Modern Approach to Teaching LVEF Assessment to Medical Students.
Status: COMPLETED
Conditions: Medical Education
Interventions: OTHER: 4 short PLMs group 1|OTHER: 4 short PLMs group 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study
Status: RECRUITING
Conditions: Severe Hemophilia A
Interventions: DRUG: Nuwiq
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin for the Treatment of Pediatric Autoimmune Disorders Associated With Streptococcal Infections
Status: COMPLETED
Conditions: Autoimmune Disease|Mental Disorder|Obsessive Compulsive Disorder|Streptococcal Infection|Tic Disorder
Interventions: DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors
Status: COMPLETED
Conditions: Neoplasms by Site
Interventions: BIOLOGICAL: Denenicokin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Same-day Antiretroviral Therapy With BIC/F/TAF
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Bictegravir / Emtricitabine / Tenofovir Alafenamide Oral Tablet [Biktarvy]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy, Biological Therapy, and Bone Marrow Transplantation in Treating Patients With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Leukemia|Neutropenia
Interventions: BIOLOGICAL: filgrastim|DRUG: amsacrine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: idarubicin|DRUG: mitoxantrone hydrochloride|DRUG: thioguanine|DRUG: tretinoin|PROCEDURE: allogeneic bone marrow transplantation|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Impact of Interscalene Block on Sleep Disordered Breathing
Status: COMPLETED
Conditions: Sleep Disordered Breathing|Obstructive Sleep Apnea
Interventions: PROCEDURE: Interscalene Block|PROCEDURE: Superior Trunk Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Compared the Efficacy and Safety of CDOP Combined With Chidamide and CDOP in de Novo Peripheral T Cell Lymphoma Patients
Status: UNKNOWN
Conditions: Peripheral T Cell Lymphoma
Interventions: DRUG: chidamide|DRUG: cyclophosphamide|DRUG: liposomal doxorubicin|DRUG: vincristine|DRUG: prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Azathioprine in the Prevention of Ileal Crohn's Disease Postoperative Recurrence.
Status: TERMINATED
Conditions: Crohn Disease|Recurrence|Azathioprine|Prevention
Interventions: DRUG: Azathioprine|DRUG: Azathioprine in case of endoscopic recurrence|PROCEDURE: Ileocolonoscopy|PROCEDURE: Small bowel follow trough
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum Monoinfection
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: KAE609
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Ankylosing Spondylitis|Psoriatic Arthritis|Crohn´s Disease|Ulcerative Colitis|Plaque Psoriasis
Interventions: DRUG: Adalimumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BCG to Reduce Absenteeism Among Health Care Workers During the COVID-19 Pandemic
Status: COMPLETED
Conditions: Covid19|Morbidity|Absenteeism
Interventions: BIOLOGICAL: BCG-Denmark|BIOLOGICAL: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Interest of GLP1 Analogues in Overweight Type 2 Diabetic Patients With Chronic Inflammatory Bowel Disease
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Diabetes Mellitus, Type 2
Interventions: OTHER: GLP1 analogues
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects
Status: COMPLETED
Conditions: Anticoagulation
Interventions: DRUG: Apixaban|DRUG: Cofact (4-Factor PCC)|DRUG: Beriplex P/N (4-Factor PCC)|DRUG: Placebo (Saline solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Controlled Trial of Community-based Nutritional, Physical and Cognitive Training Intervention Programmes for At Risk Frail Elderly
Status: COMPLETED
Conditions: Pre-Frail or Frail State
Interventions: DIETARY_SUPPLEMENT: Nutritional Intervention|OTHER: Physical Exercise|OTHER: Cognitive Training|OTHER: Combined|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Regional Chemotherapy in Locally Advanced Pancreatic Cancer: RECLAP Trial
Status: COMPLETED
Conditions: Histologically or Cytologically Confirmed Pancreatic Ca|Unresectable or Borderline Resectable Pancreatic Ca
Interventions: DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of At-home Gait Rehabilitation Using Wearable Exoskeletal Robot
Status: NOT_YET_RECRUITING
Conditions: Stroke|Gait, Spastic|Gait, Hemiplegic
Interventions: DEVICE: Wearable exoskeletal robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monoclonal Antibody 3F8 and Sargramostim in Treating Patients With Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: anti-GD2 murine IgG3 monoclonal antibody 3F8|BIOLOGICAL: anti-GD2 murine IgG3 monoclonal antibody 3F8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Status: RECRUITING
Conditions: Medulloblastoma, Childhood|Cognitive Impairment
Interventions: DRUG: Metformin hydrochloride (HCl) 500mg tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Test Efficacy of Real-time Reminders on Apple Watch To Decrease Late or Missed Meal Boluses
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Klue App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers (SURPASS-2)
Status: TERMINATED
Conditions: Esophageal Cancer|Esophagogastric Junction Cancer
Interventions: GENETIC: Autologous genetically modified ADP-A2M4CD8 cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban
Status: TERMINATED
Conditions: Aortic Valve Disease|Aortic Valve Stenosis|Aortic Valve Failure
Interventions: DRUG: Apixaban 5 MG|DRUG: Apixaban 2.5 MG|DRUG: Warfarin|DEVICE: On-X Aortic Mechanical Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Nasal high flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Care Transitions App for Patients With Multiple Chronic Conditions
Status: NOT_YET_RECRUITING
Conditions: Heart Failure|Congestive Heart Failure|Diabetes|Diabetes Mellitus|Chronic Kidney Diseases
Interventions: BEHAVIORAL: Care Transitions App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Albumin Bound Paclitaxel Plus S-1 as the First Line Chemotherapy in Advanced or Recurrent Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: Albumin Bound Paclitaxel|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Attention Modulation of Local and Global Inhibition Mechanisms
Status: RECRUITING
Conditions: Optical Phenomena
Interventions: BEHAVIORAL: experience 1 "The negative priming task"|BEHAVIORAL: experience 2 "Stop signal task"|BEHAVIORAL: experience 3 "Anti-saccades"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers
Status: COMPLETED
Conditions: Reflux Oesophagitis
Interventions: DRUG: YF476|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vaccine Therapy With or Without Sargramostim in Treating Patients With Cancer
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: recombinant fowlpox-CEA(6D)/TRICOM vaccine|BIOLOGICAL: recombinant vaccinia-CEA(6D)-TRICOM vaccine|BIOLOGICAL: sargramostim|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Minocycline in Patients With Pulmonary Nontuberculous Mycobacterial Disease
Status: RECRUITING
Conditions: Mycobacterium Avium Complex Pulmonary Disease
Interventions: DRUG: Minocycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate LB1410 in Combination With LB4330 in Patients With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: LB1410|DRUG: LB4330
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Holotranscobalamin as Compared to Plasma Cobalamins for Assessment of Vitamin B12 Absorption
Status: COMPLETED
Conditions: Vitamin B12 Absorption
Interventions: DRUG: Vitamin B12 (Cyanocobalamin)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Safety of 30 mg and 60 mg Oral Daily Dose of Ospemifene in the Treatment of Vulvar and Vaginal Atrophy (VVA) in Postmenopausal Women With Intact Uterus
Status: COMPLETED
Conditions: Atrophy|Vaginal Diseases
Interventions: DRUG: Ospemifene (Dose 1)|DRUG: Ospemifene (Dose 2)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Post-discharge Potentially Inappropriate Medications Among Older Adults
Status: COMPLETED
Conditions: Polypharmacy|Deprescription|Aged
Interventions: OTHER: MedSafer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
Status: COMPLETED
Conditions: Cervical Intervertebral Disc Disease|Cervical Spinal Stenosis|Cervical Radicular Pain|Herpes Zoster|Postherpetic Neuralgia
Interventions: PROCEDURE: Fluoroscopic-guided cervical epidural access
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure.
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Actos|DRUG: aleglitazar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma
Status: RECRUITING
Conditions: Lung Non-Small Cell Carcinoma|Malignant Solid Neoplasm|Melanoma|Renal Cell Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Positron Emission Tomography|OTHER: Questionnaire Administration|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation and Evaluation of an Evidence-Based, Multilevel Lifestyle Intervention for Underserved and Rural Populations in South Texas
Status: RECRUITING
Conditions: Cancer Prevention
Interventions: BEHAVIORAL: Enhanced TSSC curriculum|BEHAVIORAL: Original TSSC curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada
Status: COMPLETED
Conditions: Sickle Cell Disease|Sickle Cell Trait|Beta-Thalassemia|Sickle Cell-Beta Thalassemia|Sickle Cell-SS Disease
Interventions: DIAGNOSTIC_TEST: High performance liquid chromatography|DEVICE: Automated sickling test|DIAGNOSTIC_TEST: HbS solubility test|DEVICE: HemoTypeSC|DEVICE: Sickle SCAN|DEVICE: Gazelle Hb Variant Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single-dose Study to Describe the Safety of Sarilumab and Tocilizumab in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: sarilumab SAR153191 (REGN88)|DRUG: tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose Trial to Investigate the Safety and Tolerability of XEN-D0501 in Patients With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: XEN-D0501, 1 mg/tablet|DRUG: XEN-D0501, 2 mg/tablet|DRUG: XEN-D0501, 4 mg/tablet|DRUG: XEN-D0501, 8 mg/tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Capsulectomy vs Capsulotomy in Total Hip Arthroplasty. Clinical Outcomes and Proprioception Evaluation
Status: SUSPENDED
Conditions: Hip Arthrosis
Interventions: PROCEDURE: Capsulectomy in Direct Anterior Total Hip Arthroplasty|PROCEDURE: Capsulotomy in Direct Anterior Total Hip Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria
Status: UNKNOWN
Conditions: Hypercalciuria; Idiopathic|Nephrolithiasis
Interventions: OTHER: Diet for calciuria prevention|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety & Immunogenicity of Pneumococcal Vaccine 2189242A Co-administered With DTPa-HBV-IPV/Hib in Healthy Infants
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK 2189242A (LD formulation 1)|BIOLOGICAL: Pneumococcal vaccine GSK 2189242A (HD formulation 2)|BIOLOGICAL: Synflorix|BIOLOGICAL: Prevenar 13|BIOLOGICAL: Infanrix Hexa (DTPa-HBV-IPV/Hib)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: C-MAC Video-stylet for Double- Lumen Tracheal Intubation
Status: UNKNOWN
Conditions: Single Lung Ventilation|Thoracic Anesthesia
Interventions: DEVICE: C-MAC video-stylet|DEVICE: Macintosh laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Study of Open Mesh Repair in Local Anesthesia Versus Cost-optimized Laparoscopic Repair for Inguinal Hernia
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Mesh repair for primary inguinal hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Three Dimensional Transesophageal Echocardiography for Percutaneous Device Closure in Atrial Septal Defect
Status: RECRUITING
Conditions: Atrial Septal Defect|Successful Device Closure
Interventions: DEVICE: Transcatheter device closure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Relative Bioavailability Study of Gabapentin 400 mg Capsules Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Gabapentin 400 mg capsules|DRUG: NEURONTIN® 400 mg capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Medicines Gaps Study
Status: UNKNOWN
Conditions: Adherence, Medication|Statin Adverse Reaction|Anticoagulant Adverse Reaction
Interventions: BEHAVIORAL: Questionnaires to report barriers to medication adherence
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of 12-week Trehalose Intake in Patients With Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver
Interventions: DIETARY_SUPPLEMENT: Trehalose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: S0629, Observation or Combination Chemotherapy, Bortezomib, Thalidomide, and Rituximab Followed By Two Autologous Peripheral Blood Stem Cell Transplants in Treating Patients With Waldenstrom Macroglobulinemia
Status: WITHDRAWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: rituximab|DRUG: bortezomib|DRUG: carmustine|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: melphalan|DRUG: thalidomide|PROCEDURE: autologous-autologous tandem hematopoietic stem cell transplantation|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Alpha-Cyclodextrin on Fecal Fat Excretion
Status: WITHDRAWN
Conditions: Obesity|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Alpha-cyclodextrin and digestible starch|DIETARY_SUPPLEMENT: Alpha-cyclodextrin|DIETARY_SUPPLEMENT: Digestible starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lacidipine and Losartan on 24 Hour Systolic Blood Pressure Variability in Elderly Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: lacidipine (4 mg) or losartan (50 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Balloon to Induce Labor in Generous Women.
Status: TERMINATED
Conditions: Maternal Obesity
Interventions: COMBINATION_PRODUCT: Balloon catheter + oral misoprostol|DRUG: Oral misoprostol alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Cisplatin and Gemcitabine in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: chemotherapy|DRUG: cisplatin|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Determine the Effect of a Mouthwash on the Preservation of the Ecology of the Oral Microbiome and Its Compatibility With Health
Status: UNKNOWN
Conditions: Buccal Microbiota
Interventions: OTHER: buccotherm mouthwash|OTHER: placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combining Medications for the Treatment of Alcohol Dependence: An Inpatient Preliminary Study
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Topiramate and Naltrexone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial Comparing Carbonated Drink With Water as a Solvent for Colonoscopy Solution
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Sodium phosphate|DIETARY_SUPPLEMENT: Water|DIETARY_SUPPLEMENT: Zero calorie carbonated drink
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Pilot Study of Electronic Uterine Contraction Inhibitor
Status: WITHDRAWN
Conditions: Prematurity
Interventions: DEVICE: Electrical Inhibition (EI) Uterine Pacemaker
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Vitamin D Treatment in Mortality Reduction Due to COVID-19.
Status: COMPLETED
Conditions: SAR|SARS Pneumonia
Interventions: DRUG: Vitamin D|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Enhanced Counseling and Observed Therapy on Antiretroviral Adherence in People With HIV
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: BEHAVIORAL: Motivational interviewing with cognitive behavioral therapy|BEHAVIORAL: Modified directly observed therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of IMM 101 in Combination With Standard of Care in Patients With Metastatic or Unresectable Cancer
Status: TERMINATED
Conditions: Metastatic Cancer
Interventions: BIOLOGICAL: IMM-101|DRUG: Gemcitabine|DRUG: Nabpaclitaxel|DRUG: Capecitabine|DRUG: Folinic Acid|DRUG: Fluorouracil|DRUG: Irinotecan|DRUG: Oxaliplatin|BIOLOGICAL: cetuximab|BIOLOGICAL: Anti-PD1|BIOLOGICAL: Ipilimumab|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AppenDectomy Vs ANti TNF-a in Inducing Clinical and EnDoscopic Remission in Left-sided Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: PROCEDURE: Appendectomy|DRUG: Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prone Versus Supine Positioning and the Impact on Bronchopulmonary Dysplasia in Very Low Birth Weight Infants.
Status: TERMINATED
Conditions: Prone Positioning|Bronchopulmonary Dysplasia
Interventions: OTHER: Prone positioning for a total of 6 hours daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Liver Resection With Versus Without Hepatic Inflow Occlusion for the HBV-related HCC
Status: UNKNOWN
Conditions: Liver Cancer|Surgery
Interventions: PROCEDURE: non-occlusion technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Solifenacin With Bladder Training Versus Solifenacin Alone in Patients With Overactive Bladder (SOLAR)
Status: COMPLETED
Conditions: Overactive Bladder|Urinary Incontinence|Urge Incontinence
Interventions: DRUG: Solifenacin succinate|BEHAVIORAL: Simplified bladder training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Visceral Leishmaniasis
Interventions: BIOLOGICAL: LEISH-F3 + SLA-SE|BIOLOGICAL: LEISH-F3 + GLA-SE
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Influence of TaKeTiNa Music Therapy, Traditional Chinese Acupuncture and Clown Theatrical Performance on Quality of Life and the Therapeutic Process of Patients Undergoing Allogenic Stem Cell Transplantation
Status: TERMINATED
Conditions: Hematological Neoplasm|Graft-Versus-Host Disease|Depression|Stem Cell Transplant Complications|Quality of Life|Leukemia
Interventions: BEHAVIORAL: Clown theatrical Performance|PROCEDURE: Acupuncture|BEHAVIORAL: Music Therapy TaKeTiNa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thoracic Lymphatic Pump Technique Exercises Chronic Mechanical Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain, Mechanical
Interventions: OTHER: Thoracic lymphatic pump technique|OTHER: Exercises (stretching and strenghtening )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Bioavailability of Fenofibric Acid and Rosuvastatin From 5/45 mg Strength of ABT-143 Relative to That From the Coadministration of ABT-335 (Fenofibric Acid) 45 mg and Rosuvastatin Calcium 5 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ABT-143|DRUG: ABT-335|DRUG: rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CD19/CD22-targeted Chimeric Antigen Receptor Engineered T Cell (CART) in B-Cell Acute Lymphoblastic Leukemia.
Status: RECRUITING
Conditions: Leukemia, B-cell
Interventions: BIOLOGICAL: CART-19/22
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of HFMT in Promoting Donor-site Wound Healing
Status: COMPLETED
Conditions: Wound Heal
Interventions: OTHER: HFMT cell suspension|OTHER: Mupirocin ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Implantable Cardioverter-Defibrillator (ICD) Implantation in the Elderly
Status: TERMINATED
Conditions: Cardiomyopathy|Coronary Artery Disease|Congestive Heart Failure|Myocardial Infarction
Interventions: DEVICE: Implantable Cardioverter Defibrillator|OTHER: Optimal Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease
Status: TERMINATED
Conditions: Encephalopathy|White Matter Hyperintensities|Impaired Oxygen Delivery
Interventions: OTHER: Hyperbaric Oxygen Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Evaluation of the 24-Hour Coverage: Efficacy of Rotigotine
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RESET-medication Glucocorticoid Receptor (GR) Blockade as Disease Modifying Treatment for Depression With Childhood Trauma
Status: UNKNOWN
Conditions: Major Depressive Disorder|Childhood Trauma
Interventions: DRUG: Mifepristone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndromes|Chronic Myelomonocytic Leukemia|AML|MDS|CMML
Interventions: DRUG: CFI-400945|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of DMUC5754A Administered Intravenously to Patients With Platinum-Resistant Ovarian Cancer or Unresectable Pancreatic Cancer
Status: COMPLETED
Conditions: Ovarian Cancer, Pancreatic Cancer
Interventions: DRUG: DMUC5754A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Over Needle vs Catheter Through Needle
Status: COMPLETED
Conditions: Nerve Block|Catheterization
Interventions: DEVICE: E-Catheter (Pajunk)|DEVICE: Sonolong Catheter (Pajunk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Nuun Electrolyte Tablets on Hydration Status in Active Men and Women
Status: COMPLETED
Conditions: Hydration
Interventions: DIETARY_SUPPLEMENT: Nuun electrolyte tablet|OTHER: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Methylphenidate on Energy Intake and Energy Expenditure
Status: UNKNOWN
Conditions: Obesity
Interventions: DRUG: MPH|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Studies of Tacrolimus in Transplant Patients
Status: COMPLETED
Conditions: Kidney Transplant Recipients|Liver Transplant Recipients
Interventions: DRUG: Prograf|DRUG: Tacrolimus|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spirometry and Methacholine Challenge Test in Asthmatic Children Age 3-6years
Status: TERMINATED
Conditions: Asthma|Recurrent Cough
Interventions: DRUG: Methachoine|DEVICE: spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring
Status: RECRUITING
Conditions: Sickle Cell Disease
Interventions: OTHER: management on hydroxyurea by therapeutic pharmacological monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Active Hexose Correlated Compound in Tuberculosis-HIV (Human Immunodeficiency Virus) Infection
Status: COMPLETED
Conditions: Tuberculosis|Human Immunodeficiency Virus
Interventions: DIETARY_SUPPLEMENT: Active Hexoses Correlated Compound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-mFBG LAFOV PET/CT Compared to 123I-mIBG Scintigraphy SPECT/CT for Evaluation of Children With Neuroblastoma
Status: RECRUITING
Conditions: Neuroblastoma
Interventions: DIAGNOSTIC_TEST: 18FmFBG imaging on the Large Field of View PET/CT (Total body PET/CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Cryoablation Versus BCG Instillation Therapy for High-risk NMIBC
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: PROCEDURE: Transurethral cryoablation|PROCEDURE: Transurethral resection of bladder tumor|DRUG: Bcg Intravesical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Antiviral Efficacy After Switching to Generic Entecavir 1 mg for Chronic Hepatitis B
Status: UNKNOWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Switching to Generic Entecavir (Baracle®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Early Efficacy Study of TBX-2400 in Patients With AML or Myelofibrosis
Status: NOT_YET_RECRUITING
Conditions: Myelofibrosis|Acute Myelogenous Leukemia
Interventions: BIOLOGICAL: TBX-2400
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palpatory and Ultrasound Assessment of Cervical Dysfunctions and the Effect of Cervical High Velocity Low Amplitude (HVLA) Technique
Status: COMPLETED
Conditions: Cervical Dysfunction
Interventions: PROCEDURE: Cranial Vault Hold|PROCEDURE: Cervical HVLA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intranasal Dexmedetomidine for Pain Management During Screening for Retinopathy of Prematurity
Status: NOT_YET_RECRUITING
Conditions: Retinopathy of Prematurity|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Placebo-Controlled Trial of Atorvastatin in HIV-Positive Patients Not on Antiretroviral Therapy
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Combination Study of Kadcyla (Trastuzumab Emtansine) and Capecitabine in Participants With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Metastatic Breast Cancer (mBC) or HER2-Positive Locally Advanced/Metastatic Gastric Cancer (LA/mGC)
Status: TERMINATED
Conditions: Breast Cancer|Gastric Cancer
Interventions: DRUG: Capecitabine|DRUG: Trastuzumab emtansine (T-DM1)|DRUG: Trastuzumab emtansine (T-DM1)|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens
Status: NOT_YET_RECRUITING
Conditions: Alcohol Prevention|Harm Reduction
Interventions: BEHAVIORAL: Experimental: Augmented Reality ("No Time Wasted")
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of Ciprofloxacin 1000 mg ER Tablets of Dr. Reddy's Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Fed
Interventions: DRUG: CIPRO®XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Edi Level and Cardiopulmonary Function Between HHHFNC and Unheated Humidified High-Flow Oxygen Mask in COPD
Status: TERMINATED
Conditions: Chronic Obstructive Lung Disease|Respiratory Insufficiency
Interventions: DEVICE: HHHFNC|DEVICE: UHFOM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study on the Effect of Cervical Mobilization on Motor Function and Pressure Pain Threshold in Pain Free Individuals
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Passive cervical mobilisation|OTHER: Manual contact
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ALK21-003: Study of Medisorb® Naltrexone (VIVITROL®) in Alcohol-Dependent Adults
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Medisorb naltrexone 190 mg|DRUG: Medisorb naltrexone 380 mg|DRUG: Placebo matching Medisorb naltrexone 190 mg|DRUG: Placebo matching Medisorb naltrexone 380 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Safety and Efficacy Study AGN-19920 in Patients With Persistent Erythema Associated With Rosacea
Status: COMPLETED
Conditions: Erythema|Rosacea
Interventions: DRUG: Oxymetazoline HCL Cream 1.0%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Network Control TMS fMRI
Status: TERMINATED
Conditions: Attention Deficit Hyperactivity Disorder|Attention Deficit Disorder|Working Memory
Interventions: DEVICE: Transcranial Magnetic Stimulation (TMS)|PROCEDURE: High controllability TMS target
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anti-inflammatory and Anti-thrombotic Therapy With colcHicine and Low Dose Rivaroxaban for Major Adverse Cardiovascular Events Reduction in Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Rivaroxaban 2.5 Mg Oral Tablet|DRUG: Colchicine 0.5 MG|DRUG: Placebo Rivaroxaban|DRUG: Placebo Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION