pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Vitamin C in Post-cardiac Arrest
Status: ACTIVE_NOT_RECRUITING
Conditions: Cardiac Arrest
Interventions: DRUG: Vitamin C|DRUG: Thiamine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: ABI-H2158|DRUG: Itraconazole|DRUG: Rifampin|DRUG: Midazolam|DRUG: Ethinyl Estradiol / Levonorgestrel|DRUG: Esomeprazole|DRUG: Placebo matching oral contraceptive
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Platelet Rich Plasma Injection Combined With Exercise Rehabilitation in Patients With Rotator Cuff Tear
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: BIOLOGICAL: Platelet-Rich Plasma|DRUG: Hyaluronic Acid|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Combination of Valsartan + Amlodipine in Hypertensive Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan + amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium-90 (Y90) Glass Microspheres PET/CT in Imaging Patients With Liver Tumors
Status: COMPLETED
Conditions: Primary Malignant Liver Neoplasm
Interventions: PROCEDURE: Computed Tomography (CT)|PROCEDURE: Positron Emission Tomography (PET)|DEVICE: 90-Yttrium (Y-90) Glass Microspheres|DIAGNOSTIC_TEST: Technetium 99mTc albumin aggregated (99mTc-MAA)|PROCEDURE: Single-photon emission computerized tomography (SPECT) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Computer-Based Training in Patients With Post-Chemotherapy Cognitive Impairment
Status: COMPLETED
Conditions: Breast Cancer|Cognitive Symptoms|Memory Disorders
Interventions: DEVICE: Computer-based Cognitive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Escalating Doses of AGS67E Given as Monotherapy in Subjects With Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: AGS67E
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High-Intensity Training for Men With Prostate Cancer on Active Surveillance: A Feasibility Study
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: High-intensity interval training (HIIT)|BEHAVIORAL: High-Intensity resistance training (HIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gemcitabine and Imatinib Mesylate in Treating Patients With Recurrent or Metastatic Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)
Status: COMPLETED
Conditions: Mitochondrial Function, Bioenergetics|Muscle Function|Aging
Interventions: DIETARY_SUPPLEMENT: Mitopure|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dapansutrile in Diabetes and Diabetes-Related Complications - Dapan-Dia
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapansutrile|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Stratification of Risks of Conversion of Radiologically Isolated Syndromes (RIS) by Identifying Biomarkers in Serum and Cerebrospinal Fluid.
Status: NOT_YET_RECRUITING
Conditions: Radiologically Isolated Syndrome|Multiple Sclerosis
Interventions: OTHER: Observational
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intravenous Infusion of Prostaglandins as Therapy in Patients With Anterior Non-arteritic Ischemic Optic Neuropathy
Status: UNKNOWN
Conditions: Ischemic Optic Neuropathy
Interventions: DRUG: Alprostadil 20 micrograms|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Vitamin B12 in Pregnant Indian Women
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIETARY_SUPPLEMENT: Vitamin B12|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating The Co-Administration Of Moxidectin And Midazolam In Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moxidectin|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utilization of Transanal Endoscopy in the Treatment of Anastomotic Stenosis
Status: RECRUITING
Conditions: Anastomotic Stenosis
Interventions: PROCEDURE: Transanal and transabdominal combined endoscopic resection of rectal stenosis and anal reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardio Pulmonary Exercise Testing in Patients Post the Fontan Palliation in Comparison With Patients With Repaired Congenital Heart Disease and Healthy Volunteers.
Status: UNKNOWN
Conditions: Fontan Palliation|Congenital Heart Disease
Interventions: OTHER: Cardio Pulmonary Exercise Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Benefit of IQP-AS-118 on Blood Pressure and LDL-cholesterol
Status: COMPLETED
Conditions: Blood Pressure|Low Density Lipoprotein Cholesterol Level
Interventions: DIETARY_SUPPLEMENT: IQP-AS-118|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients
Status: COMPLETED
Conditions: Advanced Illness Patients With Opioid Induced Constipation
Interventions: DRUG: SC Methylnaltrexone|DRUG: SC Placebo|DRUG: SC Methylnaltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy Alone for the Treatment of Stage 1 and 2 Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma
Status: COMPLETED
Conditions: Ann Arbor Stage I Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue|Extranodal Marginal Zone Lymphoma
Interventions: OTHER: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Opioids in Epidural Solutions
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: IMCgp100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab
Status: COMPLETED
Conditions: Malignant Glioma|Glioblastoma
Interventions: DRUG: MRZ|DRUG: BEV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition
Status: RECRUITING
Conditions: Cognitive Impairment
Interventions: DRUG: metaxalone m640|DRUG: tizanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: BGB-DXP604 Alone and in Combination With BGB-DXP593 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BGB-DXP604|DRUG: BGB-DXP593|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
Status: RECRUITING
Conditions: Endosseous Dental Implant Failure|Accident Caused by Broken Ceramic
Interventions: DEVICE: Dental Implant|DEVICE: Monolithic Zirconia (MZ)|DEVICE: Zirconia-Feldspathic (PVZ)|DEVICE: Monolithic Zirconia (FCMZ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparative, Pharmacokinetic and Pharmacodynamic Study of Subcutaneous Injections of INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.
Status: COMPLETED
Conditions: Pharmacokinetic Bioequivalence Study in Human Healthy Volunteers
Interventions: COMBINATION_PRODUCT: INTP5|COMBINATION_PRODUCT: US Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Therapy Exercises and Physiotherapy Delivered Operant Conditioning in the Treatment Chronic Low Back Pain
Status: COMPLETED
Conditions: Chronic Nonspecific Low Back Pain
Interventions: BEHAVIORAL: Graded Activity|BEHAVIORAL: Group-based Therapy Exercise|BEHAVIORAL: Back School
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wear of Enamel Antagonist to ZLS Crowns
Status: UNKNOWN
Conditions: Wear, Tooth|Wear, Occlusal
Interventions: OTHER: glazed zirconium lithium silicate|OTHER: polished zirconium lithium silicate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does the Single Use of Intravenous Dexamethasone Enhance Analgesic Quality of Pudendal Analgesia in Children Undergoing Hypospadias Surgery?
Status: COMPLETED
Conditions: Pediatric Patients Undergoing Hypospadias Surgery
Interventions: DRUG: normal saline|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of PPAR Ligands on Ectopic Fat Accumulation and Inflammation
Status: COMPLETED
Conditions: Metabolic Syndrome X|Prediabetic State
Interventions: DRUG: Fenofibrate 145mg PO QD|DRUG: Pioglitazone 45 mg PO QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Elucid Labs AIDA™ - Labelled Image Acquisition Protocol
Status: UNKNOWN
Conditions: Melanoma (Skin)|Basal Cell Carcinoma of the Skin|Squamous Cell Carcinoma of the Skin
Interventions: DEVICE: Artificial Intelligence Dermatology Assistant (AIDA™)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safe Brain Initiative, Operationalizing Precision Anaesthesia
Status: RECRUITING
Conditions: Neurocognitive Disorders|Post Operative Delirium|Pain|Nausea|Vomiting|Wellbeing|Shivering|Anxiety|Stress|Agitation,Psychomotor|Sedation Complication|Thirst|Satisfaction, Patient|Temperature Change, Body|Fasting|Sore-throat|Hearing and Vision Loss
Interventions: BEHAVIORAL: Patient reported ourcomes
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Olaparib+Bevacizumab to SCLC patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of the Amaranth Medical APTITUDE Bioresorbable Drug-Eluting Coronary Stent
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Ischemia
Interventions: DEVICE: AmM APTITUDE Bioresorbable Drug-Eluting Coronary Scaffold
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of NK510 to Treat NSCLC
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: NK510|DRUG: Tislelizumab，atezolizumab or sugemalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Home-Based Prehabilitation Exercise Intervention for Improving Physical Function in Patients With Bladder Cancer and Upper Tract Urothelial Cancer, Get Moving Trial
Status: RECRUITING
Conditions: Bladder Cancer|Urothelial Carcinoma|Upper Tract Urothelial Carcinoma
Interventions: OTHER: Best Practice|OTHER: Exercise Intervention|OTHER: App-Based Intervention|OTHER: App-Based Intervention|OTHER: Interview|OTHER: Wearable Activity Tracker|OTHER: Physical Performance Testing|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Arimoclomol in Amyotropic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Arimoclomol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multimorbidity and Sarcopenia Feasibility Study in Chronic Kidney Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Kidney Diseases|Sarcopenia
Interventions: DIAGNOSTIC_TEST: Cystatin C eGFR|OTHER: Bioimpedance Analysis (Body composition analysis)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Insoluble Yeast Beta-glucan Intake on Pre-diabetic Patients
Status: UNKNOWN
Conditions: Pre-diabetic
Interventions: DIETARY_SUPPLEMENT: Yeast Beta-glucan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of a Surgical Guide for Dental Implantology
Status: COMPLETED
Conditions: Dental Implantation, Endosseous|Dental Implants|Minimally Invasive Surgical Procedures|Surgery, Oral|Surgery, Computer-Assisted
Interventions: DEVICE: SMART Guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Oxaliplatine-Paclitaxel in Patients With Metastatic Germ Cell Tumor Refractory to Cisplatin
Status: COMPLETED
Conditions: Neoplasms, Germ Cell and Embryonal
Interventions: DRUG: Oxaliplatin, Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Evaluation of Methods to Reduce Hyperemia Associated With Bimatoprost Therapy for Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma
Interventions: DRUG: Bimatoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Efficacy and Safety of IPI-504 With Trastuzumab Pretreated, Locally Advanced or Metastatic HER2 Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer|HER2 Positive Breast Cancer|Metastatic Breast Cancer|Cancer of the Breast
Interventions: DRUG: IPI-504|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Regulation in Adolescents With FASD: The Efficacy of a Targeted Intervention
Status: COMPLETED
Conditions: Self-regulation|Adolescents|Fetal Alcohol Spectrum Disorder
Interventions: BEHAVIORAL: Self-Regulation Intervention adapted from the Alert Program ®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Regimen to Prevent Atony and Postpartum Hemorrhage During Vaginal Delivery: 3-arm RCT
Status: COMPLETED
Conditions: Uterine Atony|Postpartum Hemorrhage
Interventions: DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Subconscious on Mohs Micrographic Surgery
Status: COMPLETED
Conditions: Basal Cell Carcinoma|Squamous Cell Carcinoma
Interventions: BEHAVIORAL: relaxation therapy 1|BEHAVIORAL: relaxation therapy 2|BEHAVIORAL: relaxation therapy 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Intravenous Nalbuphine on PONV With Intrathecal Morphine in Abdominoplasty.
Status: UNKNOWN
Conditions: Abdominal Obesity
Interventions: DRUG: Intrathecal Morphine|DRUG: Intrathecal Morphine + Intravenous Nalbuphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies
Status: COMPLETED
Conditions: Solid Tumors, Advanced Solid Tumors
Interventions: DRUG: RO6870810
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
Status: RECRUITING
Conditions: Neuroinflammatory Response|Nerve Injury|Nerve Damage|Neurotoxicity|Nerve Degeneration|Genotoxicity
Interventions: OTHER: exposure to organophosphates
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UNcovering the Difference Between Ranibizumab and Aflibercept, Focusing on Systemic Anti-vascular Endothelial Growth Factor (VEGF) Effects in Patients With neovascuLar Age-related Macular Degeneration (AMD)
Status: COMPLETED
Conditions: Neovacular Age-related Macular Degeneration
Interventions: PROCEDURE: Neovascular Age-related Macular Degeneration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Pneumatic Anti-Shock Garment for Obstetrical Hemorrhage: Zambia and Zimbabwe
Status: COMPLETED
Conditions: Hypovolemic Shock|Hemorrhage
Interventions: DEVICE: non-pneumatic anti-shock garment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Overweight and Obesity
Interventions: OTHER: Honey Spice Group
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A New Method: the Third Space Robotic and Endoscopic Cooperative Surgery (TS-RECS)
Status: COMPLETED
Conditions: Gastric Soft Tissue Neoplasm
Interventions: PROCEDURE: the third space robotic and endoscopic cooperative surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis
Status: COMPLETED
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: probiotic containing L.rhamnosus R0011 strain|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Cancers
Interventions: DRUG: Lorazepam|DRUG: Placebo|DRUG: Haloperidol decanoate|BEHAVIORAL: Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sub Regional Micronutrient Survey in Ethiopia
Status: UNKNOWN
Conditions: Iron-deficiency|Vitamin A Deficiency|Zinc Deficiency
Interventions: OTHER: Women of Gamo Gofa|OTHER: Children of Gamo Gofa|OTHER: Women of West Gojjam|OTHER: Children of West Gojjam|OTHER: Women of Kamashi|OTHER: Children of Kamashi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Use of Azithromycin and Rifabutin Administered 3 Times Weekly for the Treatment of M. Avium Complex (MAC) Lung Disease
Status: COMPLETED
Conditions: Mycobacterium Avium Complex
Interventions: DRUG: Azithromycin|DRUG: Rifabutin/rifampin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GTI-2040 and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: GTI-2040|DRUG: gemcitabine hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beetroot Juice - Effects on Performance in Chronic Obstructive Pulmonary Disease Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease Moderate
Interventions: DIETARY_SUPPLEMENT: Dietary beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Liposomal Bupivacaine vs Bupivacaine With Dexmedetomidine in Erector Spinae Plane Blocks for Mastectomies
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dexmedetomidine|DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Latanoprost Slow Release Insert
Status: TERMINATED
Conditions: Primary Open Angle Glaucoma (POAG)|Ocular Hypertension (OHT)
Interventions: DRUG: Latanoprost|DRUG: Arm 2|DRUG: Latanoprost SR insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natriuretic Peptide's Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
Status: COMPLETED
Conditions: Headache|Migraine
Interventions: DRUG: Natriuretic peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Anti-Platelets in Chronic Obstructive Pulmonary Disease
Status: RECRUITING
Conditions: COPD|Emphysema|Emphysema or COPD
Interventions: COMBINATION_PRODUCT: dual anti-platelet therapy|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Ibrutinib in Combination With Pomalidomide and Dexamethasone in Subjects With Relapsed/Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Ibrutinib|DRUG: Pomalidomide|DRUG: Dexamethasone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotective Efficacy of Postnatal Magnesium Sulphate in Term Infants With Birth Asphyxia
Status: NOT_YET_RECRUITING
Conditions: Birth Asphyxia
Interventions: DRUG: Magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Case-Series Examination of a Brief CAT-Informed Intervention (CATCH-Y) for Young People That Have Self-Injured
Status: COMPLETED
Conditions: Non-Suicidal Self Injury
Interventions: OTHER: Cognitive Analytic Therapy for Containing Self-Harm in Young People
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Safety and Efficacy of Topical Omiganan in Patients With External Genital Warts
Status: COMPLETED
Conditions: Condylomata Acuminata (External)
Interventions: DRUG: Omiganan (CLS001) topical gel|DRUG: Vehicle topical gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AL01211 in Healthy Volunteers
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney
Interventions: DRUG: AL01211 or Placebo (Part A)|DRUG: AL01211 or Placebo (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Two-Arm Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Chinese Participants With HER2-Positive Early Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: HER2-positive Early Breast Cancer
Interventions: DRUG: Pertuzumab IV|DRUG: Trastuzumab IV|DRUG: Pertuzumab and Trastuzumab FDC SC|DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Docetaxel|PROCEDURE: Surgery|RADIATION: Post-Operative Radiotherapy|DRUG: Hormone Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Symptom-driven ICS/LABA Therapy for Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Status: RECRUITING
Conditions: Asthma|Nonadherence, Medication
Interventions: DRUG: Adherence to symptom driven budesonide/formoterol as compared to adherence to maintenance ICS and symptom-driven SABA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Multi-Channel Automated Diet and Physical Activity Intervention for Pre-Diabetics
Status: COMPLETED
Conditions: Pre-diabetes|Diabetes|Obesity
Interventions: BEHAVIORAL: Alive-PD|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Forodesine Hydrochloride (BCX-1777) for B-Cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: forodesine hydrochloride (BCX-1777)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SPN-810 as Adjunctive Therapy in Children With Impulsive Aggression Comorbid With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Impulsive Aggression Comorbid With ADHD
Interventions: DRUG: SPN-810|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Compare the Safety, Tolerability, and Pharmacokinetics of QBX258 in Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: VAK694|DRUG: VAK694 placebo|DRUG: QAX576|DRUG: QAX576 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet
Status: COMPLETED
Conditions: Menstrual Migraine
Interventions: DRUG: Treximet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of TEZ/IVA in Subjects Aged 6 Through 11 Years With Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: TEZ/IVA|DRUG: IVA|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: gp100-fowlpox vaccine|BIOLOGICAL: therapeutic autologous lymphocytes|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Uniportal and Tubeless Video Assisted Thoracic Surgery and Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Disease
Status: UNKNOWN
Conditions: Surgical Lung Biopsy|Transbronchial Lung Cryobiopsy|Interstitial Lung Disease
Interventions: DIAGNOSTIC_TEST: lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Kinect Motion Capture to Measure Shoulder Motion in Patients Undergoing Capsular Distension for Adhesive Capsulitis
Status: UNKNOWN
Conditions: Adhesive Capsulitis|Adhesive Capsulitis of Shoulder|Frozen Shoulder|Shoulder Frozen|Shoulder Pain|Mobility Limitation
Interventions: OTHER: Kinect motion tracking system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: AtriClip® Left Atrial Appendage Exclusion Concomitant to Structural Heart Procedures (ATLAS)
Status: COMPLETED
Conditions: Post-Operative Atrial Fibrillation
Interventions: DEVICE: AtriClip® Gillinov-Cosgrove™ LAA Exclusion Systems|DRUG: Anticoagulation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Trial of the Efficacy and Safety of Levilimab (BCD-089) in Patients With Severe COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Levilimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: αPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors
Status: UNKNOWN
Conditions: Non-small-cell Lung Cancer|Mesothelioma
Interventions: BIOLOGICAL: αPD1-MSLN-CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
Status: RECRUITING
Conditions: Hyperandrogenism|Polycystic Ovary Syndrome|Puberty
Interventions: DRUG: Spironolactone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacokinetics/Pharmacodynamics Biomarker Study in Active Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: BIOLOGICAL: Anrukinzumab|BIOLOGICAL: Anrukinzumab|BIOLOGICAL: Anrukinzumab|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Paclitaxel, Carboplatin, and Gemcitabine Versus Gemcitabine and Vinorelbine for Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of Initial Levothyroxine Dose on Neurodevelopmental and Growth Outcomes in Congenital Hypothyroidism
Status: COMPLETED
Conditions: Congenital Hypothyroidism
Interventions: DRUG: Levothyroxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics for Prophylaxis of Postoperative Hirschsprungs Associated Enterocolitis
Status: UNKNOWN
Conditions: Hirschsprung Disease
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects
Status: TERMINATED
Conditions: Pneumonia, Aspiration
Interventions: BEHAVIORAL: Chin-down position|BEHAVIORAL: Thickened liquid administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CD19 Chimeric Antigen Receptors and CD19 Positive Feeder T Cells as a Leukemia Consolidation Treatment
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia in Remission
Interventions: BIOLOGICAL: CD19 CAR-T cells and CD19 positive feeder T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion Based Regimen in de Novo Living Donor Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HRT Versus Etidronate for Osteoporosis and Fractures in Asthmatics Receiving Glucocorticoids.
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Hormone Replacement Therapy and Etidronate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose, Open-Label Pharmacokinetic Study of Bardoxolone Methyl in Subjects With Mild, Moderate, and Severe Hepatic Impairment and Normal Hepatic Function
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy
Interventions: DRUG: Bardoxolone Methyl
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Protocatechuic Acid on Biochemical Markers of Immunity Status in Healthy Adults
Status: WITHDRAWN
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: Protocatechuic Acid or PCA|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Progressive Collective-exercise Program on the Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Collective group exercise program in patients with KOA|OTHER: Orientation (without exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplementation on Hemoglobin A1c
Status: COMPLETED
Conditions: Diabetes Mellitus|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D|DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulfate in Neonatal HIE"
Status: NOT_YET_RECRUITING
Conditions: Neonates With HIE
Interventions: DRUG: Magnesium sulfate|OTHER: placebo or standard treatment)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mild Versus Conventional Ovarian Stimulation Treatment for In Vitro Fertilization
Status: COMPLETED
Conditions: Subfertility
Interventions: PROCEDURE: Mild Ovarian Stimulation Treatment|PROCEDURE: Conventional Ovarian Stimulation Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study (Candesartan 16 mg and Amlodipine 10 mg)
Status: UNKNOWN
Conditions: Hypertension
Interventions: DRUG: HL068 16/10mg|DRUG: Candesartan 16mg and Amlodipine 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Food Interaction Study on the Pharmacokinetics of Eurartesim™ (DHA and PQP)in Healthy Male Adult Volunteers
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Eurartesim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rib Fracture Analgesia Using Cryoanalgesia
Status: ACTIVE_NOT_RECRUITING
Conditions: Traumatic Rib Fracture(s)
Interventions: DEVICE: Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas)|DRUG: Intercostal nerve block ropivacaine with epinephrine|DEVICE: Sham cryoneurolysis with a Painblocker|DRUG: Placebo intercostal nerve block with normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increasing the Thickness of Soft Tissues in the Esthetic Zone Around Implants
Status: UNKNOWN
Conditions: Soft Tissue Atrophy
Interventions: PROCEDURE: Soft tissue augmentation with CTG|PROCEDURE: Soft tissue augmentation with CM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of LTBI Treatment on Glucose Tolerance and Chronic Inflammation
Status: COMPLETED
Conditions: Latent Tuberculosis|Diabetes Mellitus, Type 2
Interventions: DRUG: Rifampicin 300 Mg Oral Capsule|DRUG: Isoniazid 300 Mg ORAL TABLET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Moxibustion on Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: Herb-partitioned moxibustion|OTHER: Sham herb-partitioned moxibustion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A COMPARATIVE STUDY BETWEEN 1MG AND 3 MG OF GRANISETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN STRABISMUS OPHTHALMIC SURGERIES DURING GENERAL ANESTHESIA
Status: COMPLETED
Conditions: 1mg Vs 3 mg of Granisetron
Interventions: DRUG: Granisetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pacemaker Implantation Versus Cardioneuroablation for Functional Atrioventricular Block
Status: RECRUITING
Conditions: Atrioventricular Block
Interventions: PROCEDURE: Pacemaker implantation|PROCEDURE: Cardioneuroablation (CNA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride
Status: COMPLETED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sorafenib tosylate|DRUG: everolimus|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis of Visceral Leishmaniasis Relapses in HIV Co-infected Patients With Pentamidine: a Cohort Study
Status: COMPLETED
Conditions: Visceral Leishmaniosis|HIV-infection/Aids
Interventions: DRUG: Pentamidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tuberosity Versus Palatal Connective Tissue Graft on the Treatment of Single Maxillary Recession-type Defects
Status: RECRUITING
Conditions: Gingival Recession, Localized
Interventions: PROCEDURE: tSCTG+ CAF|PROCEDURE: pSCTG+ CAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Study of ASKB1202 in Chinese Healthy Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: BIOLOGICAL: bevacizumab|BIOLOGICAL: ASKB1202
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program
Status: COMPLETED
Conditions: Attenuated Familial Adenomatous Polyposis|Deleterious Familial Adenomatous Polyposis
Interventions: OTHER: Chart Review
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)
Status: TERMINATED
Conditions: Liver Cirrhosis, Biliary
Interventions: DRUG: INT-747|DRUG: Ursodeoxycholic Acid (URSO)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Power of Hand Reflexology in Ameliorating Anxiety, Pain, and Fatigue Among Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: BEHAVIORAL: Hand Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Protein-Sparing Modified Fast Intervention for Weight Loss in Obese Endometrial Cancer Survivors
Status: COMPLETED
Conditions: Endometrial Cancer|Obesity
Interventions: DIETARY_SUPPLEMENT: Dietary Intervention|OTHER: Informational Material|OTHER: Dietary Education|DIETARY_SUPPLEMENT: Weight Maintenance|OTHER: Average score of Obesity and Weight-Loss Quality of Life Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AGN-229666 Ophthalmic Solution for the Treatment of Seasonal or Perennial Allergic Conjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis, Allergic
Interventions: DRUG: AGN-229666
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimised Pacing Program
Status: UNKNOWN
Conditions: Pacemaker Complication|Congestive Heart Failure
Interventions: OTHER: Enhanced standard management|OTHER: Optimised heart failure management|OTHER: Standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER and CSG452
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: K-001|DRUG: K-877-ER|DRUG: CSG452
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Postoperative Chest Tube Management
Status: COMPLETED
Conditions: Lung Resection
Interventions: OTHER: Reg Pressure|OTHER: Unreg Pressure|OTHER: Active Suction (Dig)|OTHER: Active Suction (Trad)|OTHER: Passive Drainage (Dig)|OTHER: Passive Drainage (Trad)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE