pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Combined Fluorocholine Positron Emission Tomography and Magnetic Resonance Imaging (FCH-PET/MRI) in Curative Treatment of a Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Patients Eligible to a Curative Treatment for Primary HCC
Interventions: DEVICE: PET/MRI system (SIEMENS AG, Munich, Germany; distributed in France by SIEMENS S.A.S, Saint-Denis, France)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunization With gp100 Protein Vaccine in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: gp100 antigen|BIOLOGICAL: incomplete Freund's adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Role of Canagliflozin on CD34+ Cells in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Canagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized Controlled Trial: CoINTEGRATE
Status: RECRUITING
Conditions: Neurocognitive Disorders|Cognitive Dysfunction|Traumatic Brain Injury|Multiple Sclerosis|Mild Cognitive Impairment
Interventions: BEHAVIORAL: CRT|BEHAVIORAL: CBT|BEHAVIORAL: Modifiable lifestyle factors|BEHAVIORAL: Usual care Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Polydiuretic Therapy for Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus
Status: WITHDRAWN
Conditions: HF - Heart Failure|Diabetes Mellitus
Interventions: DRUG: Bumetanide 0.5 mg, dapaglifozin 5 mg, eplerenone 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effectiveness of Two Different Block in the Management of Postoperative Analgesia After Lumbar Spinal Surgery
Status: COMPLETED
Conditions: The Effect of Two Different Block Methods on Postoperative Pain Management in Lumbar Spinal Surgery
Interventions: OTHER: observational drug study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence
Status: COMPLETED
Conditions: Colorectal Adenoma
Interventions: DRUG: Berberine hydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Learning Theory to Improve Obesity Treatment
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Single food Cue Exposure Treatment|BEHAVIORAL: Multiple food Cue Exposure Treatment|BEHAVIORAL: Partial Reinforcement - Enhanced Cue Exposure Treatment|BEHAVIORAL: Partial Reinforcement -Consistent Cue Exposure Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Colchicine in ST-elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Colchicine 2 mg loading dose; 0.5 mg bid for 5 days|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reduce Patient Discomfort With Water Exchange Method During Upper Endoscopy
Status: UNKNOWN
Conditions: Patients Undergoing Diagnostic EGD
Interventions: PROCEDURE: Gastric water exchange|PROCEDURE: traditional air insufflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of Salbutamol Effect on Arterial Oxygenation in COPD Patients During One-lung Ventilation
Status: RECRUITING
Conditions: One-lung Ventilation|Chronic Obstructive Pulmonary Disease
Interventions: DRUG: 5ml of inhaled normal saline|DRUG: 2.5mg (2.5ml) of inhaled salbutamol and 2.5ml of inhaled normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EPOCH Chemotherapy and Bortezomib for Associated T-Cell Leukemia Lymphoma
Status: COMPLETED
Conditions: Leukemia-Lymphoma, Adult T-Cell
Interventions: DRUG: Bortezomib|DRUG: Etoposide|DRUG: Vincristine|DRUG: Doxorubicin|DRUG: Prednisone|DRUG: Cyclophosphamide|DRUG: Raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ExAblate Pallidotomy for Medically-Refractory Dyskinesia Symptoms or Motor Fluctuations of Advanced Parkinson's Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: ExAblate Pallidotomy|DEVICE: Sham ExAblate Pallidotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lipomodelling for Symptomatic Peri-stomal Skin Contour Abnormalities: a Pilot and Feasibility Study
Status: UNKNOWN
Conditions: Stoma
Interventions: PROCEDURE: Lipomodelling of symptomatic peri-stomal skin contour abnormalities
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion)
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: DRUG: Cytisine|DRUG: Nicotine delivered via an e-cigarette|COMBINATION_PRODUCT: Cytisine plus nicotine delivered via an e-cigarette
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Locally Advanced Pancreatic Adenocarcinoma
Interventions: DRUG: NanoPac®
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parasternal Block in Pediatric Patients Undergoing Cardiac Surgery
Status: UNKNOWN
Conditions: Pectointercostal Fascial Plane Block
Interventions: PROCEDURE: Pre-incisional Ultrasound guided (PIFP) block|PROCEDURE: Post-incisional Surgeon delivered parasternal block group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer
Status: SUSPENDED
Conditions: Basaloid Squamous Cell Carcinoma|Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Oropharyngeal Squamous Cell Carcinoma|Papillary Squamous Cell Carcinoma|Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8|Squamous Cell Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cisplatin|PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|PROCEDURE: Magnetic Resonance Imaging|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Tomography|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study
Status: RECRUITING
Conditions: Heart Failure|Chronic Obstructive Pulmonary Disease|Diabetes Mellitus|Pneumonia|Urinary Tract Infections|Fever of Unknown Origin|Deep Vein Thrombosis|Hypertension
Interventions: OTHER: Outpatient visit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery
Status: RECRUITING
Conditions: Postoperative Pain|Gynecologic Disease|Local Anesthetic Systemic Toxicity
Interventions: DRUG: Lignocaine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Workstation Ergonomics and Physiotherapy in Cervicogenic Headache.
Status: COMPLETED
Conditions: Cervicogenic Headache
Interventions: BIOLOGICAL: Ergonomic modifications|BIOLOGICAL: Physiotherapy|BIOLOGICAL: Ergonomic modifications and Physiotherapy|BIOLOGICAL: Patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Endoscopic Management Of Controlled Colo-cutaneous Fistula As A Complication of Acute Sigmoid Diverticulitis: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Fistula; Sigmoid
Interventions: PROCEDURE: endoscopic management of fistula due to sigmoid diverticulitis by clip or endostitches
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of USM-IAM-based Counselling
Status: COMPLETED
Conditions: Diabetes Type 2 on Insulin
Interventions: OTHER: The Effectiveness of USM-Insulin Adherence Module (U-IAM) for Type 2 Diabetes in Improving Insulin Adherence, Glycemic Control and Inflammation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Assess Bioequivalence of a New Tapentadol Extended-Release Tablet With Respect to a Tapentadol Extended Release Tablet Under Fasted Conditions in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tapentadol Extended Release (ER) Tamper-Resistant Formulation (TRF)|DRUG: Tapentadol Prolonged-Release Formulation 2 (PR2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study of Zelboraf (Vemurafenib) in Patients With Braf V600 Mutation Positive Metastatic Melanoma
Status: COMPLETED
Conditions: Malignant Melanoma
Interventions: DRUG: Zelboraf
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programed Intermittent Epidural Bolus Interval 90 (EI90) of 10 ml, 0.0625% Bupivacaine Plus 2 μg/mL Fentanyl
Status: COMPLETED
Conditions: Labour Pain
Interventions: DEVICE: programed intermittent epidural bolus interval 90 (EI90)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care
Status: NOT_YET_RECRUITING
Conditions: Leukemia|Lymphoma|Myeloma|Myelodysplastic Syndromes|Myeloproliferative Neoplasm
Interventions: OTHER: LLS Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Anitocabtagene-autoleucel in Relapsed or Refractory Multiple Myeloma (iMMagine-1)
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: anitocabtagene-autoleucel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
Status: COMPLETED
Conditions: Obesity
Interventions: DEVICE: TransPyloric Shuttle|DEVICE: Sham procedure|BEHAVIORAL: Lifestyle Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: BIOLOGICAL: VEGFR1-1084, VEGFR2-169|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Epicondylitis by Ultrasound-guided Local Injections of PRP (Platelet Rich Plasma)
Status: COMPLETED
Conditions: Epicondylitis
Interventions: DEVICE: ACP|OTHER: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: New Dual Therapy for Primary Treatment of Helicobacter Pylori Infection：a Pilot Study
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DRUG: Rabeprazole and Amoxicillin|DRUG: Amoxicillin and Rabeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sacral Neuromodulation in Children and Adolescents
Status: RECRUITING
Conditions: Chronic Constipation With Overflow|Encopresis With Constipation and Overflow Incontinence|Hirschsprung's Disease|Anorectal Malformations|Sacral Dysgenesis
Interventions: DEVICE: Invasive Sacral Neuromodulation|DEVICE: Non-invasive Sacral Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke
Status: UNKNOWN
Conditions: Hemiplegia
Interventions: DRUG: Time delay treatment of botulinum toxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamics, Preliminary Pharmacokinetics and Tolerability of BIBB 515 BS or Pravastatin in Hyperlipemic Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BIBB 515 BS|DRUG: Pravastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: abiraterone acetate|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Discharge Trial to Enhance Immunity in Severely Malnourished Children
Status: NOT_YET_RECRUITING
Conditions: Child Malnutrition
Interventions: DIETARY_SUPPLEMENT: Microbiota-directed food|DIETARY_SUPPLEMENT: Khichuri
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rifamycin SV-MMX® 600 mg Tablets Administered Three or Two Times Daily to Patients With IBS-D
Status: COMPLETED
Conditions: Diarrhea-predominant Irritable Bowel Syndrome
Interventions: DRUG: Rifamycin SV 600mg t.i.d.|DRUG: Rifamycin SV b.i.d. + Placebo|DRUG: Placebo t.i.d.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monocentric Retrospective Observational Study for Validation of Meta-analysis of the Metatrascryptome and Transcriptome of Eosynophyl Esophagitis
Status: NOT_YET_RECRUITING
Conditions: Eosinophilic Esophagitis
Interventions: OTHER: Formalin-fixed Paraffin-embedded (FFPE) tissue samples analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Custom-manufactured vs. Off-the-rack (OTR) Compression Hosiery for Initial Management of Venous Disease
Status: TERMINATED
Conditions: Venous Disease
Interventions: DEVICE: Custom-manufactured compression hosiery (Isobar)|DEVICE: Off-the-rack stockings (Sigvaris)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thrombophylaxis in Transurethral Surgery With Dalteparine
Status: COMPLETED
Conditions: Thrombophylaxis in Transurethral Surgery
Interventions: DRUG: dalteparine (Fragmin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating a Caregiver SMS Reminder Intervention to Reduce Immunization Drop-out in Arua, Uganda
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Polio|Measles|Hepatitis B|Haemophilus Influenzae Type b Infection
Interventions: BEHAVIORAL: SMS text reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Adapting a Parenting Intervention to Promote Healthy Screen Time Habits in Young Children With Behavior Problems
Status: COMPLETED
Conditions: Behavior Problem|Parenting
Interventions: BEHAVIORAL: Screen media adapted School Readiness Parenting Program|BEHAVIORAL: School Readiness Parenting Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber
Status: TERMINATED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Sublingual allergy immunological tablet|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cell Based Therapy for the Treatment of Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: BIOLOGICAL: Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor Affinity Enhancing Specific T Cell in Solid Tumors
Status: COMPLETED
Conditions: Liver Cancer Stage IV|Gastric Cancer Stage IV|Esophageal Cancer, Stage IV|Bone and Soft Tissue Tumors|Breast Cancer Stage IV|Bladder Carcinoma Stage IV|Prostate Carcinoma Stage IV|Thyroid Cancer Stage IV|Ovarian Cancer Stage IV|Solid Tumor
Interventions: DRUG: TAEST16001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lamivudine/Dolutegravir in Virologically Suppressed Subjects With Expected or Confirmed Resistance to Lamivudine
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Dolutegravir 50 MG / Lamivudine 300 MG Oral Tablet [Dovato]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients
Status: COMPLETED
Conditions: Sepsis|Septic Shock|Cancer
Interventions: OTHER: SELDI-TOF MS for plasmatic proteic profile
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Chemo-immunotherapy (Gemcitabine, Interferon-alpha 2b and p53 SLP) in Patients With Platinum-resistant Ovarian Cancer
Status: COMPLETED
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: Interferon Alfa-2b|DRUG: Interferon Alfa-2b|BIOLOGICAL: p53 SLP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiometabolic Effects of Dapagliflozin in Heart Failure With Reduced or Mildly Reduced Ejection Fraction
Status: UNKNOWN
Conditions: Heart Failure|Reduced Ejection Fraction
Interventions: DRUG: Dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sexual Dysfunction in Hypertensive Women
Status: RECRUITING
Conditions: Hypertension
Interventions: BIOLOGICAL: Blood sample for the determination of antihypertensives or their metabolites.|BEHAVIORAL: Questionnaire on sexual activity|BEHAVIORAL: Scale on hospital anxiety and depression|BEHAVIORAL: Morisky Questionaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CALIBER Phase 1: A Pilot Study in Normal-weight and Overweight Adults.
Status: COMPLETED
Conditions: Cardiometabolic Risk
Interventions: OTHER: Low-carbohydrate, high-fat|OTHER: High-carbohydrate, moderate-fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective, Non-interventional, Multi-center, Post-authorization Safety Study of Riociguat for Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Riociguat (ADEMPAS, BAY63-2521)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Shock Wave on Pillar Pain After Carpal Tunnel Release in Hand Burn
Status: ACTIVE_NOT_RECRUITING
Conditions: Hand Burn|Carpal Tunnel Syndrome
Interventions: DEVICE: shock wave therapy|OTHER: traditional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuropilates on Rehabilitation Programs for Chronic Stroke
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke|Occupational Therapy|Physiotherapy
Interventions: PROCEDURE: Neuropilates+occupational therapy and physiotherapy conventional|PROCEDURE: Occupational Therapy and Physiotherapy conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19
Status: NO_LONGER_AVAILABLE
Conditions: Septic Shock|Endotoxemia|COVID|Corona Virus Infection|Sepsis, Severe
Interventions: DEVICE: Toraymyxin PMX-20R (PMX Cartridge)
Study Type: EXPANDED_ACCESS
Clinical trial: Effects of School-based Yoga Program on University Students
Status: NOT_YET_RECRUITING
Conditions: Yoga|Adolescent Behavior|Emotional Regulation|Mental Health|Eating Behaviors|Well-being
Interventions: OTHER: Yoga exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sensitivity of the InSync Sentry OptiVol Feature for the Prediction of Heart Failure
Status: COMPLETED
Conditions: Heart Failure, Congestive
Interventions: DEVICE: Implantable device: monitoring of intrathoracic impedance using the OptiVol diagnostic tool.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Quantitative Chromogenic Imprinted Gene in situ Hybridization (QCIGISH)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety & Efficacy Of Eculizumab In The Prevention Of AMR In Sensitized Recipients Of A Kidney Transplant From A Deceased Donor
Status: COMPLETED
Conditions: Stage V Chronic Kidney Disease
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Following Single-dose of Valsartan in Japanese Pediatric Patients
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Disease|Nephrotic Syndrome
Interventions: DRUG: Valsartan (VAL489)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: MEC90 for Supra-inguinal Fascia Iliaca Block Performed Under Ultrasound Guidance in Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Pain Management
Interventions: OTHER: Regional Anesthesia Techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Develop and Validate a Structured Exercise Protocol and Its Efficacy in Sub Acromial Impingement Patients
Status: NOT_YET_RECRUITING
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: Structured exercise program|OTHER: Conventional Exercise Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Eletriptan for the Treatment of Migraine in Subjects Unsuccessfully Treated With Nonsteroidal Anti-inflammatory Drugs
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: eletriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reprogramming to Prevent Progressive Pacemaker-induced Remodelling
Status: COMPLETED
Conditions: Left Ventricular Dysfunction|Heart Failure, Systolic|Left Ventricular Failure|Pacemaker; Complication, Mechanical
Interventions: DEVICE: Personalised programming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 in Healthy Male Subjects With Increased Elevated LDL-C Levels.
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: AZD8233
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PLATFORM Study of Precision Medicine for Rare Tumors
Status: UNKNOWN
Conditions: Rare Tumor
Interventions: DRUG: Almonertinib 110 MG|DRUG: Dacomitinib 45 MG|DRUG: Alectinib 150 MG|DRUG: Crizotinib 250 MG|DRUG: Pyrotinib 160/80 MG|DRUG: Imatinib 400 MG|DRUG: Niraparib 200/300 MG|DRUG: Palbociclib 125mg|DRUG: Vemurafenib 240 MG|DRUG: Sintilimab 100MG|DRUG: Atezolizumab 1680 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Hetrombopag Olamine Tablets for Thrombocytopenia Induced by Chemotherapy in Advanced Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Hetrombopag|DRUG: rh-TPO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Moderate to Severe Chronic Plaque Psoriasis (PSO)
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis|Moderate to Severe Chronic Plaque Psoriasis
Interventions: DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Two Intermittent Subglottic Secretion
Status: UNKNOWN
Conditions: Ventilator Associated Pneumonia
Interventions: PROCEDURE: Subglottic secretion lavage combined with aspiration|PROCEDURE: Subglottic secretion aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemospray Versus the Combined Conventional Technique for Endoscopic Hemostasis of Bleeding Peptic Ulcers : A Pilot Study
Status: COMPLETED
Conditions: Bleeding Peptic Ulcers
Interventions: DEVICE: Hemospray|DEVICE: Combined Conventional Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ribose on B-Type Natriuretic Peptide (BNP) Levels in Congestive Heart Failure Patients
Status: TERMINATED
Conditions: Congestive Heart Failure
Interventions: DRUG: CORvalen (D-Ribose)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Moderate-to-Severe Atopic Dermatitis|Atopic Eczema
Interventions: DRUG: dupilumab|OTHER: Topical emollient (moisturizer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Diagnosis (Psychosis and Cannabismisuse): Comparison of Specialized Treatment Versus Unspecified Treatment
Status: COMPLETED
Conditions: Psychotic Disorders|Marijuana Abuse|Intervention
Interventions: BEHAVIORAL: Cannabis-Consumption-Reduction-Training|BEHAVIORAL: Social competence Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Ranibizumab in Diabetic Macular Edema
Status: TERMINATED
Conditions: Visual Impairment Due to Diabetic Macular Edema
Interventions: PROCEDURE: Active laser photocoagulation|DRUG: Sham injections|DRUG: Ranibizumab 0.5 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Study of Ganetespib in Combination With Docetaxel Versus Docetaxel Alone in Patients With Advanced NSCLC
Status: TERMINATED
Conditions: Non-Small-Cell Lung Adenocarcinoma|Non-small Cell Lung Cancer Stage IIIB|Non-small Cell Lung Cancer Stage IV|Non-small Cell Lung Cancer Metastatic
Interventions: DRUG: Docetaxel|DRUG: Ganetespib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Dextrose Prolotherapy Versus Dry Needling Therapy
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: The study group|PROCEDURE: The Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH
Status: COMPLETED
Conditions: Homozygous Familial Hypercholesterolemia
Interventions: DRUG: lerodalcibep|DRUG: evolocumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Accuracy in Rehabilitation Exercise Between Mobile Application Actuated Rehabilitation Exercise Guidance and Routine Rehabilitation Exercise Guidance for the Primary Osteoarthritis Knee Patients
Status: COMPLETED
Conditions: Mobile Application Actuated Rehabilitation Exercise Guidance|Routine Rehabilitation Exercise Guidance
Interventions: OTHER: mobile application actuated rehabilitation exercise guidance|OTHER: routine rehabilitation exercise guidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ReSET Aim 1a: Restarting Safe Education and Testing for Children With Medical Complexity - Feasibility of In-home Cohort COVID-19 Testing Strategies, and Associations With CMC Parent Perceptions About In-person School Attendance
Status: COMPLETED
Conditions: COVID-19|Children With Medical Complexity (CMC)
Interventions: DIAGNOSTIC_TEST: BinaxNOW Rapid Antigen System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: OTHER: placebo|DRUG: selenium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
Status: COMPLETED
Conditions: Disc Degenerative Disease|Spondylolisthesis|Spinal Fracture|Spinal Deformity|Spinal Stenosis|Spinal Tumor
Interventions: DEVICE: Johnson&Johnson Medical Suzhou made Spine Fusion System|DEVICE: Imported EXPEDIUM screws and OPAL cage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F-FMISO PET Guided Dose Escalation in Nasopharyngeal Carcinoma - a Feasibility and Planning Study
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: (18)F-fluoromisonidazole (FMISO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Evaluating Tigecycline vs Levofloxacin in Hospitalized With Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Community Acquired Pneumonia|Bacterial Pneumonia|Cross Infection
Interventions: DRUG: tigecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Maternal Cardiac Output Response to Rescue Norepinephrine and Phenylephrine Boluses in Patients With Severe Preeclampsia
Status: COMPLETED
Conditions: Hemodynamic Instability
Interventions: DRUG: Phenylephrine|DRUG: Norepinephrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED II)
Status: COMPLETED
Conditions: Lung Diseases|Pulmonary Embolism|Venous Thromboembolism
Interventions: DEVICE: Tomography, X-ray Computed
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of TAK-062 in Treatment of Active Celiac Disease in Participants Attempting a Gluten-Free Diet
Status: ACTIVE_NOT_RECRUITING
Conditions: Celiac Disease
Interventions: DRUG: TAK-062|DIETARY_SUPPLEMENT: Simulated Inadvertent Gluten Exposure (SIGE) Gluten-Bar|DRUG: TAK-062 Placebo|DIETARY_SUPPLEMENT: Simulated Inadvertent Gluten Exposure (SIGE) Gluten-free Bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies
Status: COMPLETED
Conditions: Accelerated Phase Chronic Myelogenous Leukemia|Adult Acute Myeloid Leukemia in Remission|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Childhood Chronic Myelogenous Leukemia|Childhood Myelodysplastic Syndromes|Chronic Phase Chronic Myelogenous Leukemia|de Novo Myelodysplastic Syndromes|Previously Treated Myelodysplastic Syndromes|Refractory Anemia|Refractory Anemia With Excess Blasts|Refractory Anemia With Excess Blasts in Transformation|Relapsing Chronic Myelogenous Leukemia|Secondary Myelodysplastic Syndromes
Interventions: PROCEDURE: umbilical cord blood transplantation|DRUG: fludarabine phosphate|DRUG: cyclophosphamide|BIOLOGICAL: ex vivo-expanded cord blood progenitor cell infusion|RADIATION: total-body irradiation|DRUG: cyclosporine|DRUG: mycophenolate mofetil|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Biweekly Capecitabine Dosing With Bevacizumab for the Treatment of Metastatic Breast Cancer Based Upon the Norton-Simon Mathematical Model
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endothelin-1 as a Potential Trigger of Migraine Aura
Status: UNKNOWN
Conditions: Migraine With Aura
Interventions: DRUG: Endothelin-1|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: PD 0332334|DRUG: Placebo|DRUG: PD 0332334|DRUG: PD 0332334
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Performance of the Automated Fluid Shunt in Patients With Ascites and Diuretic Resistance
Status: COMPLETED
Conditions: Ascites
Interventions: DEVICE: NovaShunt's Automated Fluid Shunt implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration
Status: TERMINATED
Conditions: Geographic Atrophy|Macular Degeneration
Interventions: DRUG: 400 µg Brimonidine Implant|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Activated Platelet Rich Plasma (PRP) in Human Autologous Fat Transfer
Status: COMPLETED
Conditions: Lipofilling|Human Autologous Fat Transfer
Interventions: BIOLOGICAL: Addition of PRP ( platelet rich plasma) to the lipograft|PROCEDURE: Lipofilling of the midface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Online Neuroplasticity Training for Remediation of ADHD in Adolescent Children (ONTRAC)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Cognitive Training|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FDG PET/CT Versus 18F-FDG PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: PET/MRI|DIAGNOSTIC_TEST: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Protein Turnover in Healthy and Overuse-diseased Tendon
Status: COMPLETED
Conditions: Patella; Tendinitis
Interventions: OTHER: Progressive resistance training|OTHER: Cross-sectional comparison between healthy and tendinopathic group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer
Status: NOT_YET_RECRUITING
Conditions: Sarcopenia|Non Small Cell Lung Cancer|Malnutrition
Interventions: DEVICE: Inbody 570|DEVICE: JAMAR Dynamometer|RADIATION: CT scan
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Studying the Effects of Antihypertensives on Individuals at Risk for Alzheimer's
Status: COMPLETED
Conditions: Alzheimer's Disease|Hypertension
Interventions: DRUG: Ramipril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy Dose De-escalation in HPV-Associated Cancers of the Oropharynx
Status: RECRUITING
Conditions: Oropharynx Cancer
Interventions: RADIATION: De-escalated radiation dose|RADIATION: Standard radiation dose|OTHER: 18 fluorodeoxyglucose (FDG)-positron emission tomography (PET)-Computed Tomography (CT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency
Status: COMPLETED
Conditions: Menkes Disease|Occipital Horn Syndrome|Unexplained Copper Deficiency
Interventions: DRUG: Copper Histidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Non-Nutritive Sucking (NNS) on Balance and Gait Measured in 12-42 Month-Old Healthy Children Over 36 Months
Status: RECRUITING
Conditions: Postural Balance|Gait|Non-nutritive Sucking|Sleep|Muscle Relaxation|Electroencephalography
Interventions: OTHER: Pacifier
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nafamostat Efficacy and Safety in Critically Ill Patients(NICE)
Status: UNKNOWN
Conditions: Acute Kidney Injury
Interventions: DRUG: heparinized saline priming group|DRUG: nafamostat infusion after heparinized saline priming
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study With Pazopanib in Combination With Cisplatin (CDDP) in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors|Metastatic Cancer
Interventions: DRUG: cisplatin|DRUG: Pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Status: RECRUITING
Conditions: Indolent Systemic Mastocytosis|Monoclonal Mast Cell Activation Syndrome|Smoldering Systemic Mastocytosis
Interventions: DRUG: Elenestinib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of a Web-based, Computer-tailored, Pedometer-based Physical Activity Intervention for Adults: a Cluster-randomized Controlled Trial
Status: COMPLETED
Conditions: Inactivity
Interventions: BEHAVIORAL: Physical Activity advice.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TAPS-ESP: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use Electronic Spanish Platform
Status: COMPLETED
Conditions: Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use
Interventions: OTHER: Screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: GO-203-2c|DRUG: GO-203-2c + Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SalT Reduction InterVEntion: Metabolic, Behavioral and Health Consequences of Reducing Salt in Bread
Status: COMPLETED
Conditions: Salt Intake
Interventions: OTHER: Bread with reduced salt content|BEHAVIORAL: Dietary advice|OTHER: Bread with standard salt content
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Combination Chemotherapy With or Without Etoposide in Treating Older Patients With Non-Hodgkin's Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: CHOP regimen|DRUG: EPOCH regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Training Oculo-motor Control to Improve Vision When Using a Preferred Retinal Locus
Status: NOT_YET_RECRUITING
Conditions: Central Visual Impairment
Interventions: BEHAVIORAL: Training of perception and oculo-motor control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Variable Perception of Cutaneous Stimulation
Status: COMPLETED
Conditions: Pain, Acute|Anesthesia, Local|Dermatology/Skin - Other
Interventions: DEVICE: Vibratory Anesthetic Device (VAD)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION