pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Controlled Study to Investigate the Impact of Different Intensities Training on ADL and BODE Index in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Low intensity resistance training|BEHAVIORAL: High intensity resistance training|BEHAVIORAL: Aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Risk Factor Control Before Orthopedic Surgery
Status: TERMINATED
Conditions: Osteoarthritis|Cardiovascular Disease
Interventions: DRUG: Metoprolol|DRUG: Lisinopril|DRUG: Atorvastatin|BEHAVIORAL: Lifestyle counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Gut-brain Axis in Food Reward and Alcohol Consumption
Status: COMPLETED
Conditions: Impulsivity|Alcohol Consumption
Interventions: DIETARY_SUPPLEMENT: Phospholean|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy
Status: COMPLETED
Conditions: Peripheral Neuropathy
Interventions: BEHAVIORAL: Yoga Intervention|BEHAVIORAL: Meditation Intervention|BEHAVIORAL: Reiki|OTHER: Holistic Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Rates of Colorectal Cancer Screening Among Never Screened Patients
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: BEHAVIORAL: Outreach and Reminder Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Participant-Reported Outcomes With the Accu-Chek® Solo Micropump System
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Accu-Chek® Solo micropump system|DEVICE: mylife™ OmniPod® Insulin Management System|OTHER: Multiple Daily Injections (MDI) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Human Study of an Anti-Toll-like Receptor 4 (TLR4) Monoclonal Antibody (NI-0101) in Adult Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: BIOLOGICAL: Monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance Training, Detraining, and Retraining Study 2022
Status: COMPLETED
Conditions: Exercise Training|Skeletal Muscle|Skeletal Muscle Atrophy
Interventions: OTHER: Resistance training, detraining, retraining
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: Sodium Fluoride|DRUG: vancomycin hydrochloride|DRUG: vancomycin hydrochloride|DRUG: chlorhexidine digluconate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Reduction in Saturated Fat on Cholesterol and Lipoproteins in Lean and Obese Persons
Status: COMPLETED
Conditions: Cardiovascular Disease|Dietary Modification|Cardiovascular Risk Factors
Interventions: OTHER: unsaturated fat for saturated fat|OTHER: saturated fat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort)
Status: TERMINATED
Conditions: COVID-19|Lymphocytopenia
Interventions: DRUG: Interleukin-7|DRUG: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Triprilimab(JS001) and Chemotherapy Combined With Local Treatment for Multiple Metastatic NPC
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Triprilimab(JS001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of AT1001 (Migalastat HCl) in Healthy Subjects and Subjects With Impaired Renal Function
Status: COMPLETED
Conditions: Fabry Disease
Interventions: DRUG: AT1001 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Chlorhexidine Gluconate Bladder Instillations in Patients With Chronic Suprapubic Catheters on Unplanned Healthcare Encounters and Quality of Life
Status: RECRUITING
Conditions: Neurogenic Bladder|Urinary Retention
Interventions: DEVICE: Bladder instillation with Irrisept
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Feniramidol HCl 400 mg Film Tablet (Pharmactive, Turkey) Under Fed Conditions
Status: COMPLETED
Conditions: Bioequivalence
Interventions: DRUG: Phenyramydol HCl 400 mg Film Tablet|DRUG: Cabral 400 mg Film Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study Comparing a Cohort of Women Having a Classic Caesarean to a Cohort of Women Having a FAUCS Caesarean (FAUCS)
Status: UNKNOWN
Conditions: Cesarean Section; Dehiscence|Extra Peritoneal Caesarean Section
Interventions: PROCEDURE: Caesarean
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored Studies
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: RO7234292 (RG6042)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization
Status: TERMINATED
Conditions: Opioid Use
Interventions: DRUG: Acetaminophen|DRUG: Fentanyl|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Posterior-anterior Vertebral Mobilization Followed by Prone Press-up Exercise in Nonspecific Low Back Pain
Status: RECRUITING
Conditions: Low Back Pain|Chronic Low-back Pain
Interventions: OTHER: Posterior-anterior vertebral mobilizations followed by Prone press-up exercise|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Scalp Infiltration With Diprospan Plus Ropivacaine for Postoperative Pain After Craniotomy in Adults
Status: COMPLETED
Conditions: Pain, Postoperative|Post-Craniotomy Headache
Interventions: DRUG: The DR group|DRUG: The R group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Adductor Canal Block Versus Lumbar Plexus Block for Post Operative Pain Management After Total Knee Replacement
Status: UNKNOWN
Conditions: Pain Management
Interventions: PROCEDURE: Ultrasound-guided Lumber Plexus Block|PROCEDURE: adductor canal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM
Status: ACTIVE_NOT_RECRUITING
Conditions: Methamphetamine Use Disorder
Interventions: DRUG: Naltrexone Hydrochloride|DRUG: Placebo|BEHAVIORAL: Ecological Momentary Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extraperitoneal Versus Transperitoneal Cesarean Section
Status: COMPLETED
Conditions: Cesarean, Extraperitoneal
Interventions: PROCEDURE: Extraperitoneal Cesarean|PROCEDURE: Transperitoneal Cesarean
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
Status: COMPLETED
Conditions: Metastatic Cancer|Solid Tumor|Lymphoma
Interventions: DRUG: Sym022
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Rectal Cancer (LARC)
Interventions: DRUG: NG-350A IV administration|DRUG: Capecitabine oral administration|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis
Status: RECRUITING
Conditions: Recurrent Langerhans Cell Histiocytosis|Refractory Langerhans Cell Histiocytosis
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: FDG-Positron Emission Tomography and Computed Tomography Scan|PROCEDURE: Lumbar Puncture|PROCEDURE: Multigated Acquisition Scan|DRUG: Tovorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Triiodothyronine Supplementation for Infants After Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Defects
Interventions: DRUG: Triostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-Reported Outcomes Integrated in the Follow-up of Patients With Hematological Cancer
Status: UNKNOWN
Conditions: Hematological Cancer
Interventions: OTHER: Completion of patient-reported outcome (PRO) questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immune Response to a Clade C DNA HIV Vaccine
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA-HIV-PT123 vaccine|BIOLOGICAL: Protein/MF59 vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intratracheal Umbilical Cord-derived Mesenchymal Stem Cells for Severe Bronchopulmonary Dysplasia
Status: UNKNOWN
Conditions: Bronchopulmonary Dysplasia|Extremely Premature Infants|Severe BPD That Conventional Therapies Has Failed|No Severe Congenital Anomalies|no Severe IVH Neither Cystic PVL
Interventions: BIOLOGICAL: ucMSCs|OTHER: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy and Safety of Oral SHR0302 in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Core Treatment Active Experimental: SHR0302 Dose#1|DRUG: Core Treatment Active Experimental: SHR0302 Dose#2|DRUG: Core Treatment Placebo Comparator: Placebo|DRUG: Extension Treatment Active Experimental: SHR0302 Dose#1|DRUG: Extension Treatment Active Experimental: SHR0302 Dose#2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chlorhexidine Bathing to Prevent Hospital-acquired Infections: the CLEANS Study
Status: UNKNOWN
Conditions: Chlorhexidine|Hospital-Acquired Infection|Surgery|Intensive Care Unit
Interventions: OTHER: 2% Chlorhexidine bathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasound Guided Quadratus Lumborum Block for Post Operative Analgesia After Hip Arthroplasty
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Anterior Quadratus lamborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Tricaprilin Including Food Effect on Ketone Body Production
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: tricaprilin|OTHER: standard meal|OTHER: high-fat meal|OTHER: overnight fast
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Lenalidomide in Comb w/Rituximab for Pts w/CD5+/CD20+ Hem Malignancies Who Relapse/Progress After Rituximab
Status: COMPLETED
Conditions: Lymphocytic Leukemia|Mantle Cell Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Stage II, III, or IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancers
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: ALVAC(2)-NY-ESO-1(M)/TRICOM vaccine|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regadenoson Infusion of Marginalized Donor Lungs in an EVLP System
Status: COMPLETED
Conditions: Lung Transplant
Interventions: DRUG: Regadenoson|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment Evaluation of Neuromodulation for Tinnitus (TENT-A)
Status: COMPLETED
Conditions: Tinnitus
Interventions: DEVICE: PS1|DEVICE: PS2|DEVICE: PS3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: External Shoe Lift to Improve Healing and Adherence in Patients With Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Diabetic Foot Ulcer|Peripheral Neuropathy|Treatment Adherence and Compliance
Interventions: DEVICE: External shoe lift
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identifying Student Opinion Leaders to Lead E-cigarette Interventions
Status: TERMINATED
Conditions: E-Cig Use|Adolescent Behavior
Interventions: BEHAVIORAL: Peer-Led Peer-Elected Intervention|BEHAVIORAL: Adult-Led Intervention|BEHAVIORAL: Peer-Led Non-Elected Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dose-Ranging Study of the Bimatoprost Ocular Insert
Status: COMPLETED
Conditions: Primary Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Bimatoprost|DRUG: Timolol 0.5%|DEVICE: Placebo Ocular Insert|DRUG: Placebo Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Oral Nutritional Supplements on Nutritional Status and Clinical Outcomes
Status: WITHDRAWN
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: Nutritional Supplement (Ensure Plus)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of Feet and Ankle Mobilization on Balance of Older Adults
Status: COMPLETED
Conditions: Aging Problems
Interventions: OTHER: Feet and Ankle Mobilization|OTHER: Proprioceptive Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Insect Repellents Against Musca Sorbens, the Vector of Trachoma
Status: COMPLETED
Conditions: Trachoma
Interventions: OTHER: IR3535|OTHER: Permethrin lower dose|OTHER: Permethrin higher dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effecot of Serratus Posterior Superior Intercostal Plane Block and Thoracic Paravertebral Block in VATS
Status: RECRUITING
Conditions: Video-assisted Thoracoscopic Surgery
Interventions: PROCEDURE: Group T
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery
Status: TERMINATED
Conditions: Varicose Veins|Wound Infection|Recurrence
Interventions: DRUG: Betadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Noni Juice on Lipid Peroxidation-derived DNA Adducts in Heavy Smokers
Status: COMPLETED
Conditions: DNA Damage
Interventions: DIETARY_SUPPLEMENT: Noni juice|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Status: UNKNOWN
Conditions: Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Interventions: PROCEDURE: Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a New Giomer Restorative System in Class V Restorations
Status: COMPLETED
Conditions: Non-carious Cervical Lesions
Interventions: DEVICE: SHOFU Beautifil II LS|DEVICE: 3M/ESPE Filtek Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Generic Fingolimod (Sphingomod®, Hikma) in Patients With Relapsing-Remitting Multiple Sclerosis in Egypt
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Fingolimod
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Multiple-component Workplace FRamed Intervention to Decrease Occupational Muscle Pain - FRIDOM
Status: ACTIVE_NOT_RECRUITING
Conditions: Neck Pain|Shoulder Pain|Lifestyle
Interventions: BEHAVIORAL: Multi-component lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 18F-FluoroethylCholine Positron Emission Tomography: a Promising Diagnostic Tool for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DEVICE: 18F-FluoroethylCholine PET
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Risk Stratification in Children and Adolescents With Primary Cardiomyopathy
Status: UNKNOWN
Conditions: Primary Cardiomyopathy|Dilated Cardiomyopathy|Hypertrophic Cardiomyopathy|Left Ventricular Noncompaction|Restrictive Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Volumetric Analysis of Soft and Hard Tissue Healing for Ridge Preservation and Socket Seal After Tooth Extraction
Status: COMPLETED
Conditions: Tooth Extraction
Interventions: DEVICE: Xenograft bone substitute|DEVICE: Collagen dressing|DEVICE: 3D-collagen matrix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking
Status: COMPLETED
Conditions: Bladder Cancer|Cervical Cancer|Esophageal Cancer|Gastric Cancer|Head and Neck Cancer|Kidney Cancer|Leukemia|Liver Cancer|Lung Cancer|Pancreatic Cancer|Tobacco Use Disorder
Interventions: DRUG: nicotine|DRUG: varenicline|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect on Attendance if Including Focused Information of Spirometry in Preventive Health Checks
Status: COMPLETED
Conditions: Spirometry|Patient Participation|Health Literacy|Lung Diseases
Interventions: BEHAVIORAL: focused information of spirometry in the invitation|BEHAVIORAL: standard invitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of TrueTear™ for the Treatment of Meibomian Gland Disease
Status: COMPLETED
Conditions: Meibomian Glands|Dry Eye Syndromes
Interventions: DEVICE: TrueTear™|DEVICE: Thermalon Dry Eye Compress
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Injectable Flowable Composite With Giomer Technology vs High Viscosity Glass Ionomer Restorations in ART for Cancer Patients
Status: RECRUITING
Conditions: Secondary Caries|Fracture Tooth|Discoloration, Tooth
Interventions: OTHER: giomer|OTHER: high viscosity glass ionomer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cirrhosis Medical Home
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: OTHER: Care Coordinator Intervention for Direct Intervention Group|OTHER: Care Coordinator Intervention for Standard of Care Group|OTHER: Caregiver Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Single Loop DJB Sleeve Gastrectomy for Poorly Controlled T2DM
Status: UNKNOWN
Conditions: Diabetes Mellitus|Obesity|Bariatric Surgery Candidate|Weight Loss
Interventions: PROCEDURE: Sleeve gastrectomy + duodeno-jejunal bypass|PROCEDURE: Roux-Y gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TAK-438 Compared to Placebo in the Treatment of Non-Erosive Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Non-erosive Gastroesophageal Reflux Disease
Interventions: DRUG: TAK-438|DRUG: TAK-438|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study in the Cholesterol Absorption Reduction After Consumption of Low-fat, Drinkable Fermented Milk Enriched With Plant Sterols
Status: COMPLETED
Conditions: Mildly Hypercholesterolemic Subjects
Interventions: OTHER: 1- Low fat drinkable fermented dairy product enriched with 1.6g of plant sterol (as free equivalent) per unit|OTHER: 2- Low fat drinkable fermented dairy product without plant sterols (control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of Sourdough Breads Consumption on Postprandial Responses, Satiety and Food Intake at Subsequent Meal
Status: COMPLETED
Conditions: Energy Intake|Appetite Regulation
Interventions: DIETARY_SUPPLEMENT: Wholemeal bread|DIETARY_SUPPLEMENT: Sourdough bread|DIETARY_SUPPLEMENT: Bread with sourdough
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Clinical Study to Evaluate the Efficacy and Safety of CKD-351
Status: UNKNOWN
Conditions: Primary Open-angle Glaucoma|Ocular Hypertension
Interventions: DRUG: CKD-351|DRUG: Latanoprost|DRUG: D930|DRUG: Placebo of CKD-351|DRUG: Placebo of CKD-351|DRUG: Placebo of D930
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vasopressin Injection Versus Misoprostol During Hysteroscopic Myomectomy In Reducing Blood Loss And Operation Time.
Status: COMPLETED
Conditions: Submucous Leiomyoma of Uterus
Interventions: DRUG: Misoprostol|DRUG: Vasopressin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Ann Arbor Stage I Lymphoma|Ann Arbor Stage II Lymphoma|Ann Arbor Stage III Lymphoma|Ann Arbor Stage IV Lymphoma|Chronic Lymphocytic Leukemia|Chronic Myeloid Leukemia|Gastroesophageal Junction Adenocarcinoma|Head and Neck Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|Invasive Breast Carcinoma|Kidney Carcinoma|Malignant Hepatobiliary Neoplasm|Malignant Solid Neoplasm|Melanoma|Muscle-Invasive Bladder Carcinoma|RISS Stage I Plasma Cell Myeloma|RISS Stage II Plasma Cell Myeloma|RISS Stage III Plasma Cell Myeloma|Sarcoma|Stage I Bladder Cancer AJCC v6 and v7|Stage I Breast Cancer AJCC v7|Stage I Colorectal Cancer AJCC v6 and v7|Stage I Esophageal Cancer AJCC V7|Stage I Gastric Cancer AJCC V7|Stage I Lung Cancer AJCC v7|Stage I Ovarian Cancer AJCC v6 and v7|Stage I Pancreatic Cancer AJCC v6 and v7|Stage I Prostate Cancer AJCC v7|Stage I Uterine Corpus Cancer AJCC v7|Stage II Bladder Cancer AJCC v6 and v7|Stage II Breast Cancer AJCC v6 and v7|Stage II Colorectal Cancer AJCC v7|Stage II Esophageal Cancer AJCC v7|Stage II Gastric Cancer AJCC v7|Stage II Lung Cancer AJCC v7|Stage II Ovarian Cancer AJCC v6 and v7|Stage II Pancreatic Cancer AJCC v6 and v7|Stage II Prostate Cancer AJCC v7|Stage II Uterine Corpus Cancer AJCC v7|Stage III Bladder Cancer AJCC v6 and v7|Stage III Breast Cancer AJCC v7|Stage III Colorectal Cancer AJCC v7|Stage III Esophageal Cancer AJCC v7|Stage III Gastric Cancer AJCC v7|Stage III Lung Cancer AJCC v7|Stage III Ovarian Cancer AJCC v6 and v7|Stage III Pancreatic Cancer AJCC v6 and v7|Stage III Prostate Cancer AJCC v7|Stage III Uterine Corpus Cancer AJCC v7|Stage IV Bladder Cancer AJCC v7|Stage IV Breast Cancer AJCC v6 and v7|Stage IV Colorectal Cancer AJCC v7|Stage IV Esophageal Cancer AJCC v7|Stage IV Gastric Cancer AJCC v7|Stage IV Lung Cancer AJCC v7|Stage IV Ovarian Cancer AJCC v6 and v7|Stage IV Pancreatic Cancer AJCC v6 and v7|Stage IV Prostate Cancer AJCC v7|Stage IV Uterine Corpus Cancer AJCC v7|Thyroid Gland Carcinoma
Interventions: OTHER: Questionnaire Administration|PROCEDURE: Biospecimen Collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Adjunctive Hyperbaric Oxygen Therapy (HBOT) for Lower Extermity Diabetic Ulcer:
Status: WITHDRAWN
Conditions: Ulcer Foot|Diabetic Foot Ulcer
Interventions: OTHER: HBOT|BEHAVIORAL: Standard wound care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Genentech Xenon MRI Idiopathic Pulmonary Fibrosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Hyperpolarized 129 Xenon Gas Comparing Idiopathic Pulmonary Fibrosis (IPF) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Location Specific Differences in Intestinal Brake Activation
Status: COMPLETED
Conditions: Ileal Brake|Satiety|Overweight|Obesity|Overeating
Interventions: OTHER: placebo|OTHER: Casein (in duodenum)|OTHER: Casein (in jejunum)|OTHER: Casein (in ileum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
Status: RECRUITING
Conditions: Advanced Cancer|Advanced Solid Tumor|Melanoma|Metastasis|Pleural Mesothelioma|Renal Cell Carcinoma|MSI-High|Mismatch Repair Deficiency|Colorectal Cancer|Hepatocellular Carcinoma|Hepatocellular Cancer|Renal Cell Cancer|Kidney Cancer|Skin Cancer|Non Small Cell Lung Cancer|NSCLC|Anaplastic Lymphoma Kinase Genomic Tumor Aberrations|ALK Genomic Tumor Aberrations
Interventions: DRUG: Alintegimod|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Consumer Access to Personal Health Information for Asthma Self-Management
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: mobile & web-based action plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low Frequency Soundwave Stimulation on Chemotherapy Induced Peripheral Neuropathy
Status: RECRUITING
Conditions: Gynecologic Cancer|Neuropathy;Peripheral
Interventions: DEVICE: SensoniQ Treatment Station
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rectal Spacer Hydrogel Before Radiation Therapy in Reducing Radiation Dose to the Rectum in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DEVICE: Medical Device Usage and Evaluation|PROCEDURE: CT simulation|PROCEDURE: Stereotactic body radiation therapy|RADIATION: Brachytherapy|PROCEDURE: Post-implant dosimetry scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Two Rehabilitative Treatments and Diet in the Modulation of Inflammation in Patients With Knee Prosthesis.
Status: COMPLETED
Conditions: Knee Pain Swelling
Interventions: PROCEDURE: Lymphatic drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin K Supplementation in Post-Menopausal Osteopenia
Status: COMPLETED
Conditions: Post-Menopausal Osteoporosis|Post-Menopausal Osteopenia
Interventions: DIETARY_SUPPLEMENT: vitamin K1 (phylloquinone)|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Calcium Phosphate Versus PMMA Cement in Thoracolumbar Fractures
Status: UNKNOWN
Conditions: SPINAL Fracture
Interventions: DEVICE: Kyphos FS™ Bone Substitute|DEVICE: KYPHON ActivOs® Bone Cement with Hydroxyapatite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction
Status: COMPLETED
Conditions: Heart Failure|Renal Dysfunction
Interventions: DRUG: BNP and PDE-V|DRUG: BNP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangitis
Interventions: PROCEDURE: Injection of 37℃ contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Morbid Obesity and Bariatric Surgery on Brain Inflammation, and Activation of Central Reward System
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: Bariatric Surgery (RYGB or LSG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Preventing Seroma Formation After Axillary Lymph Node Dissection for Breast Cancer by Early Vacuum Assisted Closure
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: PROCEDURE: vacuum assisted closure in experimental arm|PROCEDURE: Axillary dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neurofilament Light Chain ,Chitinase-3 Like-1 Proteins and Plasmacytoid Dendritic Cells in Multiple Sclerosis
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DIAGNOSTIC_TEST: Neurofilament Light Chain ,Chitinase-3 Like-1 Protein Levels and Tolerogenic plasmacytoid Dendritic Cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Complementary Treatment of PG2 to Improve Clinical Benefit Response and Quality of Life in Fatigue
Status: TERMINATED
Conditions: Quality of Life|Fatigue|Complementary
Interventions: DRUG: PG2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Field and High Field Magnetic Resonance Imaging Assessments on Pediatric Patients
Status: RECRUITING
Conditions: Conditions Requiring a Brain Magnetic Resonance Imaging, Head Computerized Tomography, or Head Ultrasound
Interventions: DIAGNOSTIC_TEST: Hyperfine MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Feasibility of Argatroban, Tissue Plasminogen Activator and Intra-arterial Therapy in Stroke
Status: COMPLETED
Conditions: Stroke|Cerebral Ischemia
Interventions: DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nedosiran in Pediatric Patients From Birth to 11 Years of Age With PH and Relatively Intact Renal Function
Status: RECRUITING
Conditions: Primary Hyperoxaluria|Primary Hyperoxaluria Type 1|Primary Hyperoxaluria Type 2|Primary Hyperoxaluria Type 3
Interventions: DRUG: nedosiran
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase # Clinical Study Trial of Felbinac Trometamol Injection in China
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Felbinac Trometamol Injection|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Ultrasound-guided Erector Spinae Block for Postoperative Analgesia in Laprascopic Ventral Hernia Repair.
Status: COMPLETED
Conditions: Ventral Hernia|Postoperative Pain|Regional Anesthesia
Interventions: PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical and Cognitive Training System for Neurocognitive Protection and Enhancement in Older Adults
Status: UNKNOWN
Conditions: Cognitive Decline
Interventions: DEVICE: NeeuroCycle Physical and Cognitive Training System|DEVICE: NeeuroCycle Cognitive Training System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Description of Lymphatic Damage in Encephalic Venous Thrombosis and Strictures in MRI a Reverse-recovery Sequence: a Pilot Study
Status: RECRUITING
Conditions: Description of Local Modifications of Lymph Nodes or Bundles With the FABIR Sequence in MRI
Interventions: OTHER: MRI sequences
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EROSION III: OCT- vs Angio-based Reperfusion Strategy for STEMI
Status: COMPLETED
Conditions: ST-segment Elevation Myocardial Infarction
Interventions: PROCEDURE: Optical coherence tomography-guided reperfusion strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aerosolized Aldesleukin in Treating Patients With Lung Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Lung|Metastatic Melanoma|Metastatic Osteosarcoma|Metastatic Renal Cell Cancer|Sarcoma|Stage IV Cutaneous Melanoma AJCC v6 and v7|Stage IV Osteosarcoma AJCC v7|Stage IV Renal Cell Cancer AJCC v7
Interventions: BIOLOGICAL: Aerosolized Aldesleukin|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Effects of a Passive Stretching Session on the Mechanical Properties of Medial Gastrocnemius Muscle in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: measurement evaluated with an isokinetic dynamometer|OTHER: measurement evaluated with an 2D ultrasound|OTHER: assessment of the level of discomfort
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Role of Estrogen in Luteinizing Hormone Surge and Ovulation
Status: COMPLETED
Conditions: Ovulation Disorder|Ovarian Cysts
Interventions: DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Safety and Immunogenicity Phase I Study of CryJ2-DNA-Lysosomal Associated Membrane Protein (CryJ2 -DNA-LAMP) Plasmid
Status: COMPLETED
Conditions: Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: CryJ2-DNA-LAMP plasmid vaccine by intramuscular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Lung Transplant Outcomes With Coping Skills and Physical Activity
Status: ACTIVE_NOT_RECRUITING
Conditions: Post-Lung Transplantation
Interventions: BEHAVIORAL: Coping Skills Training combined with Exercise (CSTEX)|BEHAVIORAL: Standard of Care plus Education (SOC-ED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma
Status: TERMINATED
Conditions: Cholangiocarcinoma|Liver Neoplasms
Interventions: DRUG: Floxuridine|DRUG: Dexamethasone|DRUG: Gemcitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin at Elective Cesarean Delivery Part 4
Status: COMPLETED
Conditions: Postpartum Hemorrhage
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)
Status: RECRUITING
Conditions: Adrenal Cortical Carcinoma|Medullary Thyroid Cancer|Thymic Neuroendocrine Carcinoma|Pancreatic Neuroendocrine Tumor
Interventions: BIOLOGICAL: individualized mRNA neoantigen vaccine (mRNA-0523-L001)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: YF476 and Type I Gastric Carcinoids
Status: COMPLETED
Conditions: Chronic Atrophic Gastritis|Hypergastrinaemia|Type I Gastric Carcinoids
Interventions: DRUG: YF476
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma, Not Otherwise Specified|Recurrent Cervical Carcinoma|Stage IV Cervical Cancer AJCC v6 and v7|Stage IVA Cervical Cancer AJCC v6 and v7|Stage IVB Cervical Cancer AJCC v6 and v7
Interventions: DRUG: Atezolizumab|BIOLOGICAL: Bevacizumab|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Operation Worth Living Project With Suicidal Soldiers at Ft. Stewart
Status: COMPLETED
Conditions: Suicidal Ideation Active|Suicidal and Self-injurious Behavior
Interventions: BEHAVIORAL: The Collaborative Assessment and Management of Suicidality|BEHAVIORAL: Enhanced Care as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Postnatal Discharge in a French Perinatal Network
Status: UNKNOWN
Conditions: Pregnancy Complications Nos|Labor/Delivery Problems Nos|Vitality; Newborn
Interventions: BEHAVIORAL: multi-pronged program to improve early postpartum discharge
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Hybrid-ESD+ and LiftUp® on the en Bloc/R0 Rate in Colorectal Adenomas Between 2 and 3 cm
Status: WITHDRAWN
Conditions: Colorectal Adenoma
Interventions: PROCEDURE: Hybrid ESD+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ischemic Compression Therapy and Kinesiotaping in Chronic Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: ischemic compression|OTHER: kinesio taping|OTHER: exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiopulmonary Outpatient Rehabilitation Using Mobile Technology
Status: COMPLETED
Conditions: Cardiac Disease|Pulmonary Disease|Cardiopulmonary Disease
Interventions: BEHAVIORAL: Usual Care|BEHAVIORAL: Movn application (MVN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting
Status: RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral|Bilateral Hearing Loss
Interventions: DEVICE: FS4 then TFS4 (cochlear implant)|DEVICE: TFS4 then FS4 (cochlear implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time
Status: TERMINATED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Polydextrose, low dose|DIETARY_SUPPLEMENT: Polydextrose, medium dose|DIETARY_SUPPLEMENT: Polydextrose, high dose|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent
Status: NOT_YET_RECRUITING
Conditions: Pancreaticoduodenectomy|Antibiotherapy
Interventions: DRUG: Antibioprophylaxis (Piperacillin-tazobactam)|DRUG: 5 days Antibiotherapy (Piperacillin-tazobactam)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive, Emotional, Physical and Psychosocial Effects of Panax Quinquefolius L
Status: COMPLETED
Conditions: Memory|Learning|Attention|Cognition|Well-Being
Interventions: DRUG: HT1001 extract of Panax quinquefolius L
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CLL-Irl Study. CTRIAL-IE (ICORG) 07-01, V7
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: pegfilgrastim|BIOLOGICAL: rituximab|DRUG: cyclophosphamide|DRUG: fludarabine phosphate|GENETIC: cytogenetic analysis|GENETIC: fluorescence in situ hybridization|GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: protein expression analysis|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT