pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye|Dry Eye Syndromes
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Opthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Droperidol for Prevention of Postoperative Delirium in Elderly Patients After Non-cardiac Surgery
Status: RECRUITING
Conditions: Digestive System Disease|Urologic Diseases|Gynecological Disease|Orthopedic Surgery
Interventions: DRUG: Droperidol Injection|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Erlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: ARQ 197 plus erlotinib|DRUG: Pemetrexed, docetaxel or gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fludarabine and Radiation Therapy in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Phase or Accelerated Phase Chronic Myelogenous Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: recombinant interferon alfa|BIOLOGICAL: therapeutic allogeneic lymphocytes|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: imatinib mesylate|DRUG: mycophenolate mofetil|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices
Status: NOT_YET_RECRUITING
Conditions: Chronic Pelvic Pain Syndrome|Pelvic Pain|Pelvic Varices|Pelvic Congestive Syndrome|Pelvic Pain Syndrome
Interventions: DIAGNOSTIC_TEST: Transcatheter Venography|PROCEDURE: Bilateral ovarian vein embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: IPACK Block in Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Total Knee Arthroplasty
Interventions: DRUG: Adductor Canal Block plus IPACK Block|DRUG: Adductor Canal Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First Time in Man Study of Finafloxacin Hydrochloride
Status: COMPLETED
Conditions: Helicobacter Infections|Urinary Tract Infection
Interventions: DRUG: Finafloxacin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contribution of Diaphragmatic Ultrasound for Monitoring Diaphragmatic Function in Patients With Amyotrophic Lateral Sclerosis
Status: RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: PROCEDURE: Diaphragmatic ultrasound|OTHER: Electro-physiological exploration of the diaphragm
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Inhaled AZD1402 Administered for Four Weeks in Adults With Asthma on Medium-to-High Dose Inhaled Corticosteroids
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: AZD1402|DRUG: Placebo|DRUG: Short acting beta agonist (SABA) (rescue medication)|DRUG: Run-in medications (ICS-LABA combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal Women
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: liraglutide|DRUG: placebo|DRUG: levonorgestrel / ethinylestradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: [14C]-DNL343
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter Study to Evaluate the Safety and Tolerability of Single-Dose for MEDI-545
Status: COMPLETED
Conditions: Chronic Plaque Psoriasis
Interventions: BIOLOGICAL: MEDI 545|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Expression in Lower Extremity Acute Traumatic Compartment Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Tibial Shaft Fracture|Tibial Plateau Fracture
Interventions: PROCEDURE: Acute injury without compartment syndrome|PROCEDURE: Acute injury with compartment syndrome|PROCEDURE: Exertional compartment syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Capacity Builders Inc. Navajo Youth Builders Personal Responsibility Education Innovation Strategies Project
Status: UNKNOWN
Conditions: Sexual Abstinence|Responsible Sex
Interventions: BEHAVIORAL: Native STAND|BEHAVIORAL: Regular Health/Physical Education Curriculum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RCT of Web-Based Behavioral Sleep Intervention for Individuals With Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder|Alcohol Dependence|Insomnia
Interventions: BEHAVIORAL: Sleep Healthy Using the Internet (SHUTi)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of NYX-2925 in Subjects With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: NYX-2925|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of MK0773 in Healthy Older Men (0773-004)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: MK0773|DRUG: Comparator: testosterone enanthate|DRUG: Comparator: placebo oral tablet|DRUG: Comparator: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous/Allogeneic Progenitor Stem Cell Therapy for Congestive Heart Failure
Status: TERMINATED
Conditions: Heart Failure, Congestive
Interventions: PROCEDURE: Injection of bone marrow cells in the heart|BIOLOGICAL: Biological bone marrow cell therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endocrine Cardiomyopathy in Cushing Syndrome: Response to Cyclic GMP PDE5 inhibitOrs
Status: COMPLETED
Conditions: Cushing's Syndrome Cardiomyopathy
Interventions: DRUG: Tadalafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PIFR-based Inhalation Therapy in Patients Recovering From AECOPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: PIRF measured by InCheck DIAL|DRUG: Regular treament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telepsychiatry With Randomized Waitlist Control Utilizing Patient Reported Outcome Measures
Status: COMPLETED
Conditions: PROMs|Waitlist|Telemedicine|Mental Health Disorder|Psychiatric or Mood Diseases or Conditions
Interventions: BEHAVIORAL: Patient-rated outcome measures and educational videos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Methacetin Breath Test in Patients With Liver Disease Secondary to Heart Disease
Status: TERMINATED
Conditions: Dilated Cardiomyopathy|Tricuspid Atresia
Interventions: DEVICE: Methacetin Breath Test (MBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase II Study of SHR-1210 vs Placebo as Consolidation Chemotherapy After Radical Concurrent Chemoradiotherapy in Locally Advanced ESCC
Status: UNKNOWN
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: SHR-1210|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum Cortisol Levels in Patients With Anxiety and Depression With Symptomatic Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus Related Stress
Interventions: PROCEDURE: venepuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chikungunya Virus Vaccine Trial in Healthy Adults
Status: COMPLETED
Conditions: Viral Vaccines|Chikungunya Fever|Chikungunya Virus Infection
Interventions: BIOLOGICAL: VRC-CHKVLP059-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PARQVE Prior to Total Knee Replacement
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: BEHAVIORAL: Multiprofessional and educational Program prior to Total knee replacement TKA. (PARQVE TKA).|BEHAVIORAL: Patients will be submitted to total knee replacement.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Gas Exchange Response to Indacaterol in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: PROCEDURE: Arterial blood gases|PROCEDURE: Cardiac Output|PROCEDURE: Vital signs|PROCEDURE: Exhaled breath|PROCEDURE: Spirometry|DRUG: Indacaterol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability Modulation Following a Manipulation in Pain Free Patients Versus Patients in Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: Activator methods technique|PROCEDURE: Traditional chiropractic adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Tolerability, PK and PD of SCH 900518 in Naive or Treatment-Experienced Subjects Infected With HCV Genotype 1 (Protocol No. P04695)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Drug: SCH 900518 Biologic: Peginterferon alfa-2b(PegIntron)|DRUG: Drug: SCH 900518 Biologic: Peginterferon alfa-2b|DRUG: Drug: SCH 900518 Drug: Ritonavir (RTV) Biologic: Peginterferon alfa-2b (PegIntron)|DRUG: Drug: SCH 900518 Drug: Ritonavir (RTV) Drug: Ritonavir (RTV) Biologic: Peginterferon alfa-2b (PegIntron)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PREPIC 2 : Prevention of Recurrent Pulmonary Embolism by Vena Cava Interruption
Status: COMPLETED
Conditions: Pulmonary Embolism|Venous Thrombosis
Interventions: DEVICE: ALN optional filter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: the Safety and Efficacy of N-acetyl Cysteine in Children With Drug-Resistant Epilepsy
Status: RECRUITING
Conditions: Drug Resistant Epilepsy
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo|DRUG: NAc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis.
Status: RECRUITING
Conditions: Sinusitis|Sinusitis, Acute|Rhinosinusitis|Rhinosinusitis Acute|Sinus Infection
Interventions: DRUG: Infex 400 MR|DRUG: Infex 200 IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Efficacy of Sodium Monofluorophosphate (SMPF) Toothpastes on Enamel Lesion Remineralisation
Status: COMPLETED
Conditions: Enamel Caries
Interventions: OTHER: Experimental Toothpaste containing 1450ppm SMFP|OTHER: Toothpaste containing 1450ppm SMFP|OTHER: Toothpaste with no fluoride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation Comparing the Clinical and Histologic Healing of Flap vs. Flapless Approach to Grafting
Status: COMPLETED
Conditions: Jaw, Edentulous, Partially
Interventions: PROCEDURE: Ridge Preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Allogeneic NK Cells Therapy in Patients With Advanced Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: allogeneic NK cells therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter, Randomized Controlled, Phase II Clinical Study of First-line Chemotherapy and Camrelizumab With or Without Radiotherapy in the Treatment of Oligometastatic Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer
Interventions: RADIATION: Radiotherapy group|DRUG: Camrelizumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractional CO2 Laser Combined With PRP Fluid Versus Gel in Treatment of Acne Scars
Status: UNKNOWN
Conditions: Atrophic Acne Scar
Interventions: COMBINATION_PRODUCT: Fractional laser with PRP fluid or PRP gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Functional Magnetic Resonance Imaging Response to Leptin and Pramlintide
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: DRUG: Pramlintide (Amylin)|DRUG: Placebo (Normal Saline)|DRUG: 2 Metreleptin|DRUG: Leptin plus Pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Three Drugs in Advanced Gastric Cancer Neoadjuvant Chemotherapy for Stage Ⅲ Clinical Study
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: docetaxel,0xaliplatin,capecitabine|DRUG: oxaliplatin,capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of the "Cytocapacity Test" Patients With Lymphoproliferative Diseases and High-dose Therapy
Status: COMPLETED
Conditions: Hodgkin's Disease|Non-Hodgkin Lymphomas|Multiple Myelomas
Interventions: DRUG: lenograstim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Video Aided Mindful Deep Breathing for Pain Management
Status: COMPLETED
Conditions: Musculoskeletal Pain|Ankle Injuries|Joint Instability
Interventions: OTHER: standard ankle physiotherapy or rehabilitation for chronic ankle instability
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acceptance and Commitment Therapy (ACT) Tele-Counselling
Status: COMPLETED
Conditions: Acceptance and Commitment Therapy|Caregiver Burden|Digital Health|Technology|Mental Health|Psychotherapy|Counselling|Dementia
Interventions: BEHAVIORAL: ACT Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Root Caries|NaF|SDF|Tooth Mousse
Interventions: OTHER: Group A|OTHER: Group B|OTHER: Group C|OTHER: Group D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Everolimus Versus Placebo in Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Cancer
Interventions: DRUG: Everolimus (RAD 001)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Salmon Fishmeal Ex Vivo (FishMeal Ex Vivo)
Status: COMPLETED
Conditions: Metabolic Disease|Inflammation|Endocrine; Obesity
Interventions: DIETARY_SUPPLEMENT: Salmon fishmeal|DIETARY_SUPPLEMENT: Whey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Citalopram vs Clomipramine vs Placebo in Recurrent Depression
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: Citalopram|DRUG: Clomipramine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Memory and Attention Adaptation-Training Geriatrics Intervention in Older Cancer Survivors With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Dysfunction
Interventions: BEHAVIORAL: Memory and Adaptation Training-Geriatrics
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Hypercholesterolemia
Interventions: DRUG: ezetimibe|DRUG: simvastatin|DRUG: Ezetimibe 10/Simvastatin 20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]
Status: UNKNOWN
Conditions: Coronary Artery Disease|Angina Pectoris
Interventions: DRUG: EPA and rosuvastatin|DRUG: High dose rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test GlaxoSmithKline's (GSK) Respiratory Syncytial Virus RSV Candidate Vaccine's Safety and Immune Response in Japanese Older Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSV_PreF3 Vaccine (GSK3844766A) adjuvanted with AS01B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Iodine-131 Anti-B1 Antibody for Non Hodgkin's Lymphoma (NHL) Patients With Greater Than 25% Bone Marrow Involvement
Status: COMPLETED
Conditions: Lymphoma, Non-Hodgkin
Interventions: BIOLOGICAL: Iodine-131 Anti-B1 Antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervening Factors in Tooth Color Assessment
Status: UNKNOWN
Conditions: Tooth Color
Interventions: PROCEDURE: Dental prophylaxis|PROCEDURE: Tooth color assessment by the participant|PROCEDURE: Tooth color assessment by the investigator|PROCEDURE: Tooth color assessment with SpectroShade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Evaluation of a Regimen Consisting of Peginterferon Lambda-1a + Ribavirin + Daclatasvir (Lambda + RBV + DCV) in HCV Genotype 1b Treatment naïve Patients or Prior Relapsers to Peginterferon Alfa + Ribavirin (Alfa + RBV) Therapy
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: Peginterferon Lambda-1a|BIOLOGICAL: Peginterferon Alfa-2a|DRUG: Ribavirin|DRUG: Daclatasvir|DRUG: Telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With mFOLFOX6 in Treatment-Naïve Patients With Metastatic Colorectal Cancer With or Without K-RAS Mutations, and Comparison to Cetuximab
Status: WITHDRAWN
Conditions: Colorectal Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: cetuximab|DRUG: mFOLFOX6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Study to Evaluate the Effect of SHR-1222 Injection in Postmenopausal Osteoporosis Patients
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: SHR-1222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Cognitive Behavioral Therapy (CBT) for Stress Disorders in Health Workers Involved in the Care of Patients During the Covid-19 Epidemic
Status: COMPLETED
Conditions: Stress - Prevention of Sleep Disorders, PTSD and Depression
Interventions: BEHAVIORAL: Online cognitive behavioral therapy (CBT)|BEHAVIORAL: Online bibliotherapy programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Triple vs. Dual Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation|Acute Coronary Syndrome
Interventions: DRUG: Ticagrelor + Apixaban + ASA|DRUG: Ticagrelor + Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: One Year Clinical Evaluation of Translucent Zirconia Crowns in Dental Esthetic Zone With Biologically Oriented Preparation Technique (BOPT) Versus Conventional Preparation (Randomized Clinical Trial)
Status: UNKNOWN
Conditions: Single Crowns in Aesthetic Dental Zone
Interventions: OTHER: conventional preparation design|OTHER: biologically oriented preparation technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Antibiotic Prophylaxis on Recurrent UTI in Children
Status: COMPLETED
Conditions: Urinary Tract Infection|Recurrent Urinary Tract Infection
Interventions: DRUG: Antibiotic Prophylaxis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subcutaneous Apomorphine in the Treatment of Progressive Supranuclear Palsy and Cortico Basal Degeneration (APOPARKA)
Status: COMPLETED
Conditions: Progressive Supranuclear Palsy|Corticobasal Degeneration
Interventions: DRUG: Apomorphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pilot Study of OXP001 and Brufen in Healthy Subjects
Status: COMPLETED
Conditions: NSAID Related Gastric Irritation
Interventions: DRUG: OXP001|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Analyte Levels in Blood Samples Collected Using the TAP20-C Device With Results Obtained by Fingerstick
Status: UNKNOWN
Conditions: Diabetes
Interventions: DEVICE: Fingerstick|DEVICE: TAP20-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study to Evaluate the Efficacy of VL-NL-02 on Sleep Quality.
Status: RECRUITING
Conditions: Mood and Sleep Quality
Interventions: DIETARY_SUPPLEMENT: VL-NL-02|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: ESP Block for Post Cesarean Analgesia
Status: COMPLETED
Conditions: Cesarean Section Complications
Interventions: PROCEDURE: Erector Spinae Plane (ESP) Block|DRUG: bupivacaine liposome injectable suspension|DRUG: bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Lycopene on Oxidative Stress and Markers of Endothelial Function Healthy Men
Status: COMPLETED
Conditions: Healthy Men
Interventions: DIETARY_SUPPLEMENT: lycopene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Darbepoetin Alfa for the Treatment of Anemia of Cancer
Status: COMPLETED
Conditions: Anemia|Cancer
Interventions: DRUG: Darbepoetin Alfa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzastaurin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: enzastaurin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: R-BMD in Refractory or Relapsed Lymphoma, GELTAMO Clinical Trial
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Rituximab, Bendamustine, Mitoxantrone, Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile App for Smoking Cessation and Mental Health
Status: RECRUITING
Conditions: Smoking Cessation|Mental Illness
Interventions: COMBINATION_PRODUCT: Smart-T Mental Health and NRT|COMBINATION_PRODUCT: Smart-T Mental Health+ and NRT|COMBINATION_PRODUCT: QuitGuide + NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Efficacy and Biomarker Study of JNJ-42847922 in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: JNJ-42847922|DRUG: Diphenhydramine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthodontic Treatment Via Premolar Extraction
Interventions: PROCEDURE: extraction orthodontic treatment plan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Investigating Dupilumab's Effect in Asthma by Genotype
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Dupilumab|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy as First-Line Therapy in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Assess Adverse Events and Change in Disease Activity of Oral Cariprazine Capsules in Adult Participants With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Cariprazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insecticide Treated Polyethylene Sheeting for Prevention of Malaria in Emergencies
Status: COMPLETED
Conditions: Malaria
Interventions: OTHER: Insecticide Treated Polyethylene Sheeting|OTHER: Untreated Plastic Sheeting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Cyclophotocoagulation in Glaucoma
Status: COMPLETED
Conditions: Glaucoma
Interventions: PROCEDURE: Cyclophotocoagulation protocol|PROCEDURE: Conventional cyclophotocoagulation|PROCEDURE: Modified cyclophotocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients With Cytopenia
Status: COMPLETED
Conditions: HIV Infections|Cytopenias
Interventions: DRUG: Interleukin-3
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial Comparing Traditional Pelvic Floor Rehabilitation to Pilates in Increasing Pelvic Muscles Strength.
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: BEHAVIORAL: Pilates|PROCEDURE: Pelvic muscle rehabilitation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Safety and Tolerability of Inhaled SNSP113 in Healthy Subjects and Subjects With Stable Cystic Fibrosis
Status: TERMINATED
Conditions: Lung Diseases|Pulmonary Disease|Cystic Fibrosis|Cystic Fibrosis Lung|Cystic Fibrosis Pulmonary Exacerbation|Cystic Fibrosis With Exacerbation|Respiratory Tract Disease|Pulmonary Inflammation|Multi-antibiotic Resistance|Antibiotic Resistant Infection|Lung Infection|Lung Infection Pseudomonal|Lung; Infection, Atypical Mycobacterium|Burkholderia Infections|Burkholderia Cepacia Infection|Lung Inflammation
Interventions: DRUG: Inhaled SNSP113|DRUG: Inhaled Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Chloroprocaine 3% Gel and Oxybuprocaine 0.4% Eye Drops Anesthesia in Pediatric Population
Status: RECRUITING
Conditions: Local Anesthetic
Interventions: DRUG: Chloroprocaine 3% eye gel|DRUG: Oxybuprocaine Hydrochloride 4 Mg/mL Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sensorimotor Training and Constraint Induced Movement Therapy on Upper Extremity Function in Children With Hemiplegic CP
Status: COMPLETED
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: sensorimotor training|OTHER: constraint induced movement therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder
Status: TERMINATED
Conditions: Chronic Myeloproliferative Disorders|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases|Precancerous/Nonmalignant Condition
Interventions: DRUG: tetradecanoylphorbol acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pre-procedural Ultrasound Techniques Versus Conventional Landmark Technique of Spinal Anesthesia in Elderly Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: OTHER: Landmark technique|OTHER: Ultrasound-guided paramedian technique|OTHER: Ultrasound-guided midline technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Randomised Effectiveness Study Comparing Fluticasone Furoate (FF, GW685698)/Vilanterol (VI, GW642444) With Standard Treatment in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/VI|OTHER: Existing Maintenance Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fixation and Stability of the Trident® II Clusterhole HA Shells
Status: ACTIVE_NOT_RECRUITING
Conditions: Hip Replacement Arthroplasty
Interventions: DEVICE: Trident® II Clusterhole HA Acetabular Shell|DEVICE: Trident® Hemispherical Acetabular Shell
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MLN3126 Single Rising Dose Study
Status: TERMINATED
Conditions: Healthy Volunteers
Interventions: DRUG: MLN3126|DRUG: MLN3126 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the microVAScular Dysfunction in Covid-19 ARDS
Status: UNKNOWN
Conditions: ARDS, Human|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DIAGNOSTIC_TEST: alveolar dead-space quantification|DIAGNOSTIC_TEST: Coagulation activation and impaired fibrinolysis explorations|DIAGNOSTIC_TEST: Endothelial activation / endothelial senescence
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis Adult
Interventions: OTHER: Hypertonic saline|DRUG: Isotonic saline|OTHER: ELTGOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Biolimus A9 and Everolimus Drug-Eluting Stents in Patients With ST Segment Elevation Myocardial Infarction
Status: UNKNOWN
Conditions: Coronary Heart Disease|Percutaneous Coronary Intervention
Interventions: DEVICE: biolimus A9|DEVICE: everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Delivery of Iron and Zinc Supplements: Evaluation of Interaction Effect on Biochemical and Clinical Outcomes
Status: COMPLETED
Conditions: Anemia|Diarrhea|Iron
Interventions: DIETARY_SUPPLEMENT: iron and zinc combined|DIETARY_SUPPLEMENT: iron and zinc on separate days|DIETARY_SUPPLEMENT: iron|DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand
Status: UNKNOWN
Conditions: HSIL, High Grade Squamous Intraepithelial Lesions|Anal Cancer|HPV-Related Squamous Cell Carcinoma|Human Papilloma Virus|Human Papillomavirus Infection|Ain III
Interventions: DEVICE: BARRX™ Anorectal Wand
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablation Radiotherapy Combined With Sintilimab in Early Inoperable Synchronous Multiple Primary Lung Cancer
Status: UNKNOWN
Conditions: Multiple Primary Lung Cancer
Interventions: RADIATION: Stereotactic Ablation Radiotherapy|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Degludec in Adults With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time
Status: COMPLETED
Conditions: Diabetes|Type 2 Diabetes
Interventions: DRUG: Insulin Efsitora Alfa|DRUG: Insulin Degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Foot Rehabilitation And Minimalist Shoes on Pain, Strength, and Function in Adults With Plantar Fasciopathy
Status: RECRUITING
Conditions: Plantar Fascitis|Plantar Fasciopathy|Plantar Fasciitis of Both Feet|Plantar Fasciitis of Right Foot|Plantar Fasciitis of Left Foot|Plantar Fasciitis, Chronic
Interventions: BEHAVIORAL: Home Exercise Program|BEHAVIORAL: Minimalist Shoes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Compare the Safety, Efficacy and Immunogenicity of TX05 With Herceptin® in HER2+ Early Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Breast Neoplasms|HER2-positive Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer
Interventions: BIOLOGICAL: TX05 (trastuzumab)|BIOLOGICAL: Herceptin®|DRUG: Paclitaxel|DRUG: Epirubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: placebo|DRUG: genistein|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
Status: NOT_YET_RECRUITING
Conditions: Resistant Hypertension
Interventions: DEVICE: HyperQureTM Renal Denervation (RDN) System:
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety of Repeated Doses of OP0201 Metered Dose Inhaler Compared to Placebo in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: COMBINATION_PRODUCT: Drug: OP0201|COMBINATION_PRODUCT: Drug: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: IW-6463 Safety Study in Healthy Elderly Subjects
Status: TERMINATED
Conditions: Other
Interventions: DRUG: IW-6463|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer
Status: COMPLETED
Conditions: Gallbladder Carcinoma|Metastatic Cholangiocarcinoma|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Unresectable Cholangiocarcinoma
Interventions: DRUG: Atezolizumab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Cobimetinib|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastric Outlet Obstructions Tailored Covered Stents for GOO
Status: COMPLETED
Conditions: Gastric Outlet Obstruction
Interventions: DEVICE: Standard stents MTN-CG-s-20/100|DEVICE: Tailored stents MTN-WE-20/100-A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Bioequivalence of Astellas Phama Korea Inc. "Harnal-D" in Healthy Volunteers
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: DRUG: Harnal-D Tab.|DRUG: Chong Kun Dang Tamsulosin HCl Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 68Ga-BNOTA-PRGD2 PET/CT in Healthy Volunteers and Lung Cancer Patients
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: 68Ga-BNOTA-PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Role of Local Steroid Injection in Treatment of Idiopathic Spasmodic Flat Foot in Adolescent Patients
Status: UNKNOWN
Conditions: Flatfoot
Interventions: DRUG: Triamcinolone Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iberdomide vs. Iberdomide Plus Isatuximab Maintenance Therapy Post ASCT in Newly Diagnosed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Iberdomide|DRUG: Isatuximab|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Glucocorticoid Use in Major Hepatectomy
Status: COMPLETED
Conditions: Complications
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Clonal Fetal Mesenchymal Stem Cells (cfMSCs) for the Control of Immune-related Disorders
Status: UNKNOWN
Conditions: Immune Related Disorder|Tissue Damage
Interventions: BIOLOGICAL: clonal fetal MSCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Routine Coronary Catheterization in Low Extremity Artery Disease Undergoing Percutaneous Transluminal Angioplasty
Status: UNKNOWN
Conditions: Peripheral Artery Disease|Coronary Artery Disease
Interventions: PROCEDURE: Systemic Strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dye Assisted Lymphatic Sparing Subinguinal Varicocelectomy
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: without dye varicocelectomy|PROCEDURE: without dye varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Short- and Long-term HRV Measurements After Osteopathic Myofascial Thoracic Manipulations
Status: COMPLETED
Conditions: Heart Rate Variability
Interventions: OTHER: Osteopathic manipulative treatment|OTHER: Sham therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Use of Proximal Carpal Row Versus Iliac Crest as Bone Graft in Total Wrist Fusion
Status: NOT_YET_RECRUITING
Conditions: Wrist Arthritis|Fusion; Joint
Interventions: PROCEDURE: PRC|PROCEDURE: TWA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Botox in the Healing of Surgical Wounds of the Neck
Status: COMPLETED
Conditions: Scar
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacokinetic Study Comparing Budesonide/Formoterol Easyhaler and Symbicort Turbuhaler Forte
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/formoterol Easyhaler|DRUG: Symbicort Turbuhaler|DRUG: Charcoal and Budesonide/formoterol Easyhaler|DRUG: Charcoal and Symbicort Turbuhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Efficacy and Safety of Certolizumab Pegol for Induction of Remission in Patients With Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: BIOLOGICAL: certolizumab pegol (CDP870, CZP)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Insulin Dose Adjustments for Meals Differing in Fat Content in T1DM
Status: COMPLETED
Conditions: Low Fat Meal - Unadjusted Insulin Dose|High Fat Meal - Unadjusted Insulin Dose|High Fat Meal - Adjusted Insulin Dose +30 Percent|High Fat Meal - Adjusted Insulin Dose +Split Dose
Interventions: DIETARY_SUPPLEMENT: Meal composition|DRUG: Rapid-Acting Insulin Dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT