pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Glycemic Effects of Honey
Status: COMPLETED
Conditions: Pre-diabetes
Interventions: DIETARY_SUPPLEMENT: Honey|DIETARY_SUPPLEMENT: High Fructose Corn Syrup 55 (HFCS 55)|DIETARY_SUPPLEMENT: CHO (sugar)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Remote Preconditioning on the Exercise Performance of the Elite Swimmers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Real preconditioning followed by Sham preconditioning|OTHER: Sham preconditioning followed by Real preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Nosocomial Pneumonia With Suspected Or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA)
Status: COMPLETED
Conditions: Methicillin Resistant Staphylococcus Aureus (MRSA)
Interventions: DRUG: linezolid (Zyvox)|DRUG: vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment
Status: RECRUITING
Conditions: Breast Cancer|Cognitive Impairment
Interventions: DEVICE: Anodal tDCS|DEVICE: Sham tDCS|BEHAVIORAL: Intensive cognitive training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Safety and Immunogenicity Research of Live Attenuated Varicella Vaccine After the 2 Doses Vaccination
Status: UNKNOWN
Conditions: Varicella
Interventions: BIOLOGICAL: HBV-3|BIOLOGICAL: HBV-6|BIOLOGICAL: varicella-3|BIOLOGICAL: varicella-6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Auricular Acupressure for Hemodialysis Patients With Insomnia
Status: COMPLETED
Conditions: Insomnia Chronic
Interventions: OTHER: auricular acupressure therapy|OTHER: sham auricular acupressure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of a Bivalent Influenza Peptide Conjugate Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: V512|BIOLOGICAL: Comparator: Placebo to V512
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ticagrelor Tablets 90 mg Relative to Originator Ticagrelor Tablets 90 mg
Status: NOT_YET_RECRUITING
Conditions: Healthy Subjects
Interventions: DRUG: Ticagrelor-Test product|DRUG: Ticagrelor-Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vascular Closure Device Versus Transradial Approach in Primary Percutaneous Coronary Intervention
Status: COMPLETED
Conditions: Myocardial Infarction|Complications; Device, Vascular|Injury of Radial Artery|Injury; Blood Vessel, Femoral, Artery
Interventions: PROCEDURE: Transradial primary percutaneous coronary intervention|PROCEDURE: Transfemoral primary percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Volunteer Visibility Study of Micromachined Tags for the Detection of Surgical Sponges
Status: WITHDRAWN
Conditions: Injury Due to Foreign Object Accidentally Left in Body During Surgical Operation
Interventions: RADIATION: Abdominal radiographs with microfabricated tags
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Propolis Extract, Nanovitamin C and Nanovitamin E on Desquamative Gingivitis
Status: UNKNOWN
Conditions: Desquamative Gingivitis
Interventions: PROCEDURE: dental prophylaxis + oral hygiene instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Training Language and Literacy for Children Who Use CIs
Status: COMPLETED
Conditions: Hearing Loss, Sensorineural
Interventions: BEHAVIORAL: Phonological Awareness|BEHAVIORAL: Working Memory|BEHAVIORAL: Phonological Awareness + Working Memory|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Consistency of 3 Consecutive Lots of a Novel HBV Vaccine With Single-blind Safety Evaluation Using Engerix™-B as Control
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: HBV-MPL vaccine 208129|BIOLOGICAL: Engerix™-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study Effect of Sulfasalazine on Glutamate Levels by(Magnetic Resonance Spectroscopy)MRS in Patients With Glioma
Status: COMPLETED
Conditions: Brain Tumor
Interventions: DRUG: Sulfasalazine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Effectiveness of CEM in Diagnosis of Additional Findings at Preoperative Breast Magnetic Resonance Imaging
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: contrast-enhanced spectral mammography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of a FLUid Bolus or a Low Dose VAsopressor Infusion on Cardiovascular Collapse Among Critically Ill Adults Undergoing Tracheal Intubation.
Status: UNKNOWN
Conditions: Critically Ill Adults in the ICU, Requiring Endotracheal Intubation
Interventions: DRUG: Ringer Lactate and Norepinephrine infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genistein in Treating Patients With Localized Prostate Cancer Who Are Planning to Undergo Radical Prostatectomy
Status: TERMINATED
Conditions: Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: genistein|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Navtemadlin Plus Pembrolizumab as Maintenance Therapy in Locally Advanced and Metastatic Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Navtemadlin|DRUG: Navtemadlin Placebo|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii Infection
Status: COMPLETED
Conditions: Toxoplasmosis, Cerebral|HIV Infections
Interventions: DRUG: Pyrimethamine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: PREVENTION
Clinical trial: Liraglutide in the Treatment of Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: Liraglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Therapeutic Play Applied by Using Toy Nebulizer and Toy Mask on Child's Fear and Anxiety Level
Status: COMPLETED
Conditions: Therapeutic Play|Anxiety|Fear
Interventions: COMBINATION_PRODUCT: toy nebulizer and toy mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficiency And Quality In Post-Surgical Pain Therapy After Discharge
Status: COMPLETED
Conditions: Opioid Use|Opioid Dependence|Opioid Misuse|Post-Surgical Complication
Interventions: BEHAVIORAL: Empowering patient to steer their pain management after surgery|BEHAVIORAL: Provider-facing prescription aid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cardiac Effects of Oxytocin Administrated During Cesarean Section, Signs of Myocardial Ischemia
Status: COMPLETED
Conditions: Myocardial Ischemia|Hypotension|Bloodloss
Interventions: DRUG: oxytocin|DRUG: oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-Controlled Study: Effects of Lavender Aromatherapy on Preoperative Anxiety in Breast Patients
Status: COMPLETED
Conditions: Anxiety; Generalized|Breast Diseases|Surgery
Interventions: OTHER: Lavender oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amcenestrant (SAR439859) Plus Palbociclib as First Line Therapy for Patients With ER (+) HER2(-) Advanced Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Amcenestrant-matching placebo|DRUG: SAR439859|DRUG: Palbociclib|DRUG: Letrozole|DRUG: Goserelin|DRUG: Letrozole-matching placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Glycopyrronium Cloth, 2.4% in Patients With Palmar Hyperhidrosis
Status: COMPLETED
Conditions: Palmar Hyperhidrosis
Interventions: DRUG: Glycopyrronium cloth, 2.4%|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Two Ventilation Modes NAVA (Neurally Adjusted Ventilatory Assist) Mode and Spontaneous Breathing With Inspiratory Pressure Support (IPS) Mode in Consecutive Patients Hospitalized for Acute Respiratory Failure Requiring Mechanical Ventilation With Endotracheal Tube.
Status: COMPLETED
Conditions: Acute Respiratory Failure
Interventions: DEVICE: NAVA endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: TriVascular Canadian LIFE Study: Least Invasive Fast-Track EVAR (Endovascular Aneurysm Repair)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Ovation Prime Abdominal Stent Graft System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Quetiapine on Marijuana Withdrawal and Relapse
Status: COMPLETED
Conditions: Marijuana Smoking
Interventions: DRUG: Marijuana|DRUG: Quetiapine|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Influence of Different Physical Education Pedagogical Approaches on the Health and Development of 5-6 Year Old Children
Status: COMPLETED
Conditions: Child|Child Development|Health Behavior|Physical Activity
Interventions: BEHAVIORAL: Linear|BEHAVIORAL: Nonlinear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Buprenorphine/Naloxone With Naltrexone in Opioid Dependent Adolescents
Status: WITHDRAWN
Conditions: Opiate Addiction
Interventions: DRUG: Buprenorphine/naloxone|DRUG: Naltrexone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin detemir|DRUG: insulin aspart|DRUG: insulin NPH|DRUG: human soluble insulin|DRUG: metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Pulmonary Endarterectomy on Sleep-Related Breathing Disorders in CTEPH: The IPES Trial
Status: NOT_YET_RECRUITING
Conditions: Sleep-Disordered Breathing|Chronic Thromboembolic Pulmonary Hypertension|Post Operative
Interventions: PROCEDURE: Pulmonary endarterectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of PNEUMOSTEM® in Premature Infants at High Risk for Bronchopulmonary Dysplasia (BPD) - a US Study
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: BIOLOGICAL: Human Umbilical Cord Blood Derived-Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of the Safety of Diannexin in Kidney Transplant Recipients
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Diannexin|DRUG: Placebo|DRUG: Diannexin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Ascending Dose Study With Healthy Male Volunteers and Type II Diabetic Patients
Status: TERMINATED
Conditions: Type 2 Diabetes
Interventions: DRUG: AZD6714|DRUG: Placebo|DRUG: AZD6714|DRUG: AZD6714
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Lipid-Based Nutrient Supplements (LNS) for Pregnant and Lactating Women and Their Infants
Status: COMPLETED
Conditions: Anemia|Malnutrition|Stunting
Interventions: DIETARY_SUPPLEMENT: Iron and Folic Acid (IFA)|DIETARY_SUPPLEMENT: Multiple Micronutrient (MMN) group|DIETARY_SUPPLEMENT: Lipid-based Nutrient Supplements (LNS) group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single and Multiple-Ascending Dose Study of CRN01941 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CRN01941 Oral Solution|DRUG: CRN01941 Oral Capsule|DRUG: Placebo Oral Solution|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity Study of Meningococcal Vaccine GSK134612 Given With Priorix-Tetra™ to 12-23 Month-Old Children
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: BIOLOGICAL: Meningococcal vaccine GSK134612 (Nimenrix)|BIOLOGICAL: Priorix-Tetra|BIOLOGICAL: Meningitec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Corneal Collagen Cross-linking With Hypotonic Riboflavin in Corneas Thinner Than 400 Microns
Status: COMPLETED
Conditions: Keratoconus
Interventions: PROCEDURE: Collagen cross-linking with hypotonic riboflavin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of RV4104A Ointment in Onychomycosis
Status: UNKNOWN
Conditions: Onychomycosis
Interventions: DRUG: Keratolytic/Antifungal|DRUG: Keratolytic/Antifungal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section
Status: UNKNOWN
Conditions: Epidural Anesthesia
Interventions: DEVICE: Epidural electrical stimulation (EES)|DEVICE: Loss of resistance (LOR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Fludarabine Followed by CAMPATH-1H in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Rituximab|DRUG: Fludarabine|DRUG: CAMPTH-1H
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation Versus Thoracoscopic Ablation to Patients With Permanent Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Catheter ablation|PROCEDURE: Thoracoscopic epicardial ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: ELX/TEZ/IVA|DRUG: IVA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of ZM-H1505R in Combination With ETV Compared With ETV Monotherapy in Patients With CHB
Status: RECRUITING
Conditions: Hepatitis B, Chronic
Interventions: DRUG: ZM-H1505R|OTHER: ZM-H1505R placebo|COMBINATION_PRODUCT: Baraclude
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Trilaciclib|DRUG: Sacituzumab Govitecan-hziy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Online Intervention to Reduce Self-Harm Among Persons With High Emotion-Related Impulsivity
Status: TERMINATED
Conditions: Suicidal Ideation|Deliberate Self-harm|Impulsivity
Interventions: BEHAVIORAL: Calm program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With NK Cells in High-risk AML
Status: TERMINATED
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: NK cells|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of IR3535 as a Spatial Repellent for Malaria Control.
Status: ACTIVE_NOT_RECRUITING
Conditions: Malaria
Interventions: OTHER: IR3535 (3-(N-acetyl-N-butyl) aminopropionic acid ethyl ester) house spraying
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acceptable Pressure Range for Continuous Positive Airway Pressure(CPAP) Treatment
Status: COMPLETED
Conditions: Obstructive Sleep Apnea of Adult
Interventions: DEVICE: CPAP at pressure of 10 cmH2O|DEVICE: CPAP at minimal effective pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)
Status: RECRUITING
Conditions: Myelofibrosis (PMF)|Post Essential Thrombocythemia Myelofibrosis (ET-MF)|Post Polycythemia Vera Related Myelofibrosis (PV-MF)
Interventions: DRUG: reparixin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of the Depth of Neuromuscular Blockade on Respiratory Mechanics in Moderate to Severe ARDS Patients
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Ventilator-Induced Lung Injury
Interventions: OTHER: Modulation of the depth of the neuromuscular blockade
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of 5 Days Holter and 30 Days Thumb-ECG for Detection of Atrial Fibrillation in Stroke Patients
Status: COMPLETED
Conditions: Atrial Fibrillation|Stroke
Interventions: DEVICE: Holter monitoring and Thumb ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Azilsartan Medoxomil in the Treatment of Essential Hypertension and Type 2 Diabetes in Asia
Status: COMPLETED
Conditions: Essential Hypertension|Type 2 Diabetes Mellitus
Interventions: DRUG: Azilsartan Medoxomil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pulmozyme® on Arterial Recanalization in Post-thrombectomy Patients Managed for Ischemic Stroke (NETs-target)
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Administration of dornase alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paravertebral Blocks for Breast Cancer Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Nerve Block
Interventions: PROCEDURE: GA + paravertebral block|PROCEDURE: GA + sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anticoagulation Therapies Effect on the Endometrial Blood Flow and Pregnancy Outcomes in Unexplained Recurrent Implantation Failure Women
Status: UNKNOWN
Conditions: Recurrent Implantation Failure
Interventions: DRUG: Low dose aspirin|DRUG: Low molecular weight heparin|DRUG: Low dose aspirin plus low molecular weight heparin|DRUG: no treatment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Intradermal Administration of ZOSTAVAX™ (V211-051 AM2)
Status: COMPLETED
Conditions: Herpes Zoster
Interventions: BIOLOGICAL: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Subcutaneous|BIOLOGICAL: ZOSTAVAX™ (Zoster Vaccine Live) 1/3 Dose Subcutaneous|BIOLOGICAL: ZOSTAVAX™ (Zoster Vaccine Live) Full Dose Intradermal|BIOLOGICAL: ZOSTAVAX™ (Zoster Vaccine Live) Partial Doses Intradermal|BIOLOGICAL: Full Dose Intradermal Placebo|BIOLOGICAL: Intradermal Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Closing the Loop 24/7 in Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 1|Glucose Metabolism Disorders|Endocrine System Diseases
Interventions: DEVICE: Closed-loop system|DEVICE: real-time CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vojta Therapy on Upper Extremity Function of Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy|Upper Extremity|Vojta Therapy
Interventions: PROCEDURE: Vojta therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atherosclerosis, Immune Mediated Inflammation and Hypoestrogenemia in Young Women
Status: COMPLETED
Conditions: Estrogen Deficiency|Cardiovascular Disease (CVD)|Hypothalamic Amenorrhea
Interventions: DRUG: 17beta Estradiol|DRUG: Transdermal placebo patch|DRUG: Progesterone|DRUG: Placebo Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized, Controlled Study on Short-term Psychotherapy After Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: BEHAVIORAL: Psychotherapy|DRUG: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fascial-muscular Lengthening Therapy in the Patients With Chronic Low Back Pain.
Status: COMPLETED
Conditions: Chronic Low Back Pain
Interventions: OTHER: fascial- muscular lengthening therapy|OTHER: Stretching's of iliopsoas muscle|OTHER: the conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Canadian Study of the Effectiveness of Tresiba® (Insulin Degludec) After Switching Basal Insulin in a Population With Type 1 or Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AEQUALIS™ FLEX REVIVE™ Study (REVIVE)
Status: ENROLLING_BY_INVITATION
Conditions: Rheumatoid Arthritis|Osteoarthritis Shoulder|Fractures Humerus|Avascular Necrosis|Correction of Functional Deformity|Traumatic Arthritis|Revision of Other Devices if Sufficient Bone Stock Remains|Rotator Cuff Tears
Interventions: DEVICE: Aequalis Flex Revive Shoulder System
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Ceramic-on-Ceramic and Ceramic-on-Highly-Cross-Linked Polyethylene Bearings
Status: COMPLETED
Conditions: Osteonecrosis|Osteoarthritis
Interventions: PROCEDURE: Ceramic on Ceramic bearing|PROCEDURE: Ceramic on Highly crosslinked polyethylene bearing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Extended Use of Recombinant Human Parathyroid Hormone (rhPTH(1-84)) in Hypoparathyroidism
Status: COMPLETED
Conditions: Chronic Hypoparathyroidism|Hypoparathyroidism
Interventions: DRUG: rhPTH(1-84)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Lidocaine, Used to Attenuate Pain With Propofol Injection, on Defibrillation Threshold Testing
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pharmacodynamic Study to Better Understand the Therapeutic Response and Immunomodulatory Effects of Avonex in Multiple Sclerosis (MS) Patients and Healthy Volunteers
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1a (Avonex)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness Based Therapy for Insomnia in Black Women
Status: COMPLETED
Conditions: Insomnia
Interventions: BEHAVIORAL: Mindfulness-based therapy for insomnia (MBTI)|BEHAVIORAL: Healthy lifestyle intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Dose Study of SHR4640 in Healthy Subjects
Status: COMPLETED
Conditions: Gout; Hyperuricemia
Interventions: DRUG: SHR4640|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III China GT 1b Interferon (IFN) Intolerant Prev Exclude Dual
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Asunaprevir|DRUG: Daclatasvir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Rhabdomyosarcoma
Interventions: DRUG: Vincristine|DRUG: Dactinomycin|DRUG: Cyclophosphamide|PROCEDURE: Surgical Resection|PROCEDURE: Radiation|DRUG: Bevacizumab|DRUG: Sorafenib|DRUG: Myeloid Growth Factor|PROCEDURE: Lymph Node Sampling|DRUG: Irinotecan|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Etoposide Phosphate|DRUG: Doxorubicin|DRUG: Dexrazoxane|DRUG: ^1^1C-methionine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound
Status: COMPLETED
Conditions: Aortic Valve Stenosis|Extracorporeal Circulation
Interventions: PROCEDURE: Minimized Extracorporeal Circulation (MECC)|PROCEDURE: Conventional Extracorporeal Circulation (CECC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Finesse for Bolus Prandial Insulin Dosing Compared to Multiple Daily Injections
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DEVICE: Finesse|DEVICE: Pen/Syringe (Usual injection device)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Evaluation of a Self-guided Exposure-based Digital Intervention for Health Anxiety
Status: COMPLETED
Conditions: Illness Anxiety Disorder|Somatic Symptom Disorder
Interventions: BEHAVIORAL: Self-guided Exposure-based Digital Intervention for Health Anxiety
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Anlotinib in Recurrent/Metastatic Head and Neck Adenocarcinomas
Status: UNKNOWN
Conditions: Head and Neck Carcinoma|Adenocarcinoma|Recurrent Disease|Distantly Metastatic Malignant Neoplasm
Interventions: DRUG: Anlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amphetamine Extended-Release Tablets in the Treatment of Adults With ADHD
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: AMPH ER Tab 5, 10, 15 and 20 mg|DRUG: AMPH ER Tab Matching Placebo 5, 10, 15 and 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epirubicin, Docetaxel, and Capecitabine in Treating Women With Stage IIIA or Stage IIIB Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: docetaxel|DRUG: epirubicin hydrochloride|OTHER: laboratory biomarker analysis|OTHER: pharmacogenomic studies|PROCEDURE: biopsy|PROCEDURE: neoadjuvant therapy|PROCEDURE: therapeutic surgical procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Progressive Resistance Exercises in Individuals With Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee|Exercise Training|Biomarkers
Interventions: OTHER: Progresive Resistance Exercises|OTHER: No intervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: RO5083945|DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary And Renal Support During Acute Respiratory Distress Syndrome
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Acute Renal Failure
Interventions: DEVICE: Combined ECCOR and RRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Carotid PET/MRI With DOTATATE in Patients Post Head and Neck Radiation Therapy
Status: COMPLETED
Conditions: Head & Neck Cancer
Interventions: DIAGNOSTIC_TEST: PET/MRI of carotid arteries with 68Ga DOTATATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Trial to Compare the Pharmacokinetics and Safety of "BR1016C" With "BR1016D" in Healthy Volunteers
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: DRUG: BR1016C|DRUG: BR1016D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
Status: COMPLETED
Conditions: Acute Aortic Syndrome|Aortic Dissection|Penetrating Aortic Ulcer|Intramural Hematoma
Interventions: DIAGNOSTIC_TEST: 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography|DIAGNOSTIC_TEST: CT Aortic Angiogram|DIAGNOSTIC_TEST: Aortic MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Patients Engaged in Prevention: Enhancing Outreach to Increase Patient Engagement in Diabetes Prevention
Status: COMPLETED
Conditions: Preventive Health Services|Health Communication
Interventions: BEHAVIORAL: Values affirmation|BEHAVIORAL: No affirmation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Sennosid A+B and Sodium Picosulfate/Magnesium Oxide/Citric Acid for Bowel Preparation
Status: NOT_YET_RECRUITING
Conditions: Bowel Preparation
Interventions: DRUG: Sennosid A+B|DRUG: Sodium Picosulfate/Magnesium Oxide/Citric Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Single Anastomosis Duodeno-ileal Bypass With Sleeve Gastrectomy (SADI-S): A Prospective Cohort Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Morbid Obesity
Interventions: PROCEDURE: BPD-DS|PROCEDURE: SADI-S
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating IPI-504 in Patients With Gastrointestinal Stromal Tumors (GIST) Following Failure of at Least Imatinib and Sunitinib
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: retaspimycin hydrochloride (IPI-504)|DRUG: placebo|OTHER: Best supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Central Venous Catheter-related Complications in Patients Under Anticancer Treatment
Status: UNKNOWN
Conditions: Central Venous Catheter Thrombosis|Central Venous Catheter Related Bloodstream Infection|Solid Tumor|Hematologic Malignancy
Interventions: DEVICE: central venous catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Colostral Milk and Blood IL-6 Levels in Types of Labour
Status: COMPLETED
Conditions: Indications for Care in Pregnancy; Labor; and Delivery
Interventions: OTHER: The calculation of blood IL-6 and coloctral milk melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Study Evaluating Potential Interaction Between SAM-531 And Gemfibrozil When Co-Administered
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SAM-531 and gemfibrozil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Effect of Chinese Tea Flavor Liquor on Selected CVD Risk Factors
Status: COMPLETED
Conditions: Alcohols|Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Chinese tea flavor liquor|DIETARY_SUPPLEMENT: Chinese Meijiao liquor|DIETARY_SUPPLEMENT: Water control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Characterization of the Microbiome in Colonized Dystrophic and Junctional Epidermolysis Bullosa Wounds Before and After Use of APR-TD011 ® Spray Solution
Status: ENROLLING_BY_INVITATION
Conditions: Epidermolysis Bullosa
Interventions: COMBINATION_PRODUCT: APR-TD011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes
Status: COMPLETED
Conditions: Lower Extremity Chronic Ulcers in Diabetics
Interventions: BIOLOGICAL: CureXcell®|BIOLOGICAL: Sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Aprepitant Injection for Prevention of Post-operative Nausea and Vomiting
Status: NOT_YET_RECRUITING
Conditions: Post-operative Nausea and Vomiting (PONV)
Interventions: DRUG: Aprepitant Injection|DRUG: Aprepitant Injection Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: AR-15512 Ophthalmic Solution|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adherence With Iron Sprinkles Among High-Risk Infants
Status: COMPLETED
Conditions: Anemia|Iron Deficiency
Interventions: DRUG: Ferrous sulphate drops with vitamins A, D, and C|DRUG: Ferrous fumarate sprinkles with vitamins and minerals
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Cohort Zero Caries
Status: UNKNOWN
Conditions: Dental Caries|Early Childhood Caries
Interventions: BEHAVIORAL: Motivational Interview|OTHER: Traditional health education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cervical Cancer Radiotherapy by Use of VMAT, Individualized Polyradiosensitization and Interstitial Brachytherapy
Status: UNKNOWN
Conditions: Cervical Cancer
Interventions: RADIATION: Volumetric Arc Radiotherapy|RADIATION: Interstitial brachytherapy|DRUG: Cisplatin|DRUG: Gemcitabine|GENETIC: PIK3CA|GENETIC: KRAS|GENETIC: BRAF|GENETIC: RRM1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assesment of the Functional Activity of Platelets for the Differential Diagnosis of Thrombocytopathies
Status: NOT_YET_RECRUITING
Conditions: Immune Thrombocytopenia|Thrombocytopathy|Acute Leukemia|Hemorrhagic Disorders
Interventions: DIAGNOSTIC_TEST: Flow cytometry|DIAGNOSTIC_TEST: Platelet aggregation and plasma coagulation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Puncturable Atrial Septal Defect Occluder Trial (the PASSER Trial)
Status: UNKNOWN
Conditions: Atrial Septal Defect
Interventions: DEVICE: ASD closure with the novel occluder (ReAces)|DEVICE: ASD closure with normal occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tinnitus Treatment With Cochlear Implant in Single Sided Deafness
Status: COMPLETED
Conditions: Single Sided Deafness|Tinnitus|Cochlear Implant
Interventions: DEVICE: Cochlear implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Predictive Model for Early Metastasis in Cervical Cancer Patients After Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer|Radiotherapy|Distant Metastasis|Prognostic Model|Risk Factor
Interventions: RADIATION: external pelvic beam radiotherapy (EBRT) followed by individualized high-dose-rate intracavitary brachytherapy (HDR-ICBT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin|DRUG: Metformin|DRUG: Dapagliflozin Placebo|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antipsychotic and Motor Effects of ACP-103 When Administered in Combination With Haloperidol and Risperidone
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: ACP-103
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer
Status: RECRUITING
Conditions: Cervical Carcinoma|Chemoradiotherapy|Anti-programmed Cell Death Receptor 1|Immunotherapy|Immune Checkpoint Inhibitor|Survival Outcomes|Adverse Events|Early Stage Cervical Cancer|Locally Advanced Cervical Cancer
Interventions: COMBINATION_PRODUCT: Camrelizumab plus Concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Tenofovir DF|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Management in Arthtroscopic Shoulder Surgery
Status: COMPLETED
Conditions: Arthroscopic Shoulder Surgery
Interventions: OTHER: Interscalene block|OTHER: suprascapular and infraclavicular nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of an Exercise Re-training Program on Dyspnea in Patients After Acute Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia in Post-ICU
Status: COMPLETED
Conditions: Dyspnea
Interventions: OTHER: Specific exercise rehabilitation treatment|OTHER: No specific exercise rehabilitation treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Window-of-Opportunity Trial of Giredestrant +/- Triptorelin vs. Anastrozole + Triptorelin in Premenopausal Patients With ER-positive/HER2-negative Early Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Giredestrant|DRUG: Triptorelin|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prostatic Artery Embolization vs Medication for Benign Prostatic Hyperplasia
Status: TERMINATED
Conditions: BPH|Enlarged Prostate (BPH)|Prostatic Hyperplasia
Interventions: DEVICE: Prostatic Artery Embolization (HydroPearl® compressible microspheres)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Having Bariatric Surgery on the Pharmacokinetics, Safety and Efficacy of the Novel Non-nucleoside Reverse Transcriptase Inhibitor Doravirine
Status: UNKNOWN
Conditions: HIV Infections|Bariatric Surgery Candidate
Interventions: PROCEDURE: bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Dose Pharmacokinetics of MK-3866 in Participants With Hepatic Impairment (MK-3866-006)
Status: TERMINATED
Conditions: Hepatic Insufficiency|Antibacterial Agents
Interventions: DRUG: MK-3866
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate Safety and Pharmacokinetics of Escalating Single Doses and Multiple Doses of SP-8356
Status: TERMINATED
Conditions: Atherosclerosis|Ischemic Stroke
Interventions: DRUG: SP-8356|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT