pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Our Peers - Empowerment and Navigational Support
Status: UNKNOWN
Conditions: Disabled Persons
Interventions: BEHAVIORAL: Our Peers - Empowerment and Navigational Support (OP-ENS) Peer Health Navigator Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Long Non-coding RNAs WRAP53 and UCA-1 as Potential Biomarkers in Diagnosis of Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Liver Cirrhosis|Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: WRAP53, UCA-1
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Longitudinal Changes of [18F]PI-2620 Positron Emission Tomography in Subjects With Cognitively Normal, Mild Cognitive Impairment and Alzheimer's Disease
Status: COMPLETED
Conditions: Cognitively Normal|Mild Cognitive Impairment|Alzheimer Disease
Interventions: DRUG: [18F]PI-2620
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Self Soft Tissue Therapy for Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia Syndrome
Interventions: OTHER: Self-soft tissue therapy|OTHER: Fibromyalgia coping skills programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigating the Interaction Between Two Long-acting Reversible Methods of Contraception and Dolutegravir, a Treatment for HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Human Immunodeficiency Virus|Contraception|ART
Interventions: DRUG: Dolutegravir|DRUG: Levonorgestrel implant|DRUG: Depo medroxyprogesterone acetate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effect of Paratracheal Pressure on the Glottic View
Status: COMPLETED
Conditions: Paratracheal Pressure|Sellick's Maneuver|Airway Management|Cricoid Pressure
Interventions: PROCEDURE: Paratracheal pressure|PROCEDURE: Sellick's maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FemBloc® Permanent Contraception - Early Pivotal Trial
Status: ACTIVE_NOT_RECRUITING
Conditions: Contraception
Interventions: DEVICE: FemBloc|PROCEDURE: Laparoscopic bilateral tubal sterilization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Infraclavicular Brachial Plexus Block and Local Anesthesia in Arteriovenous Fistula Surgeries and Their Effects on Tissue Oxygen Saturation
Status: NOT_YET_RECRUITING
Conditions: Renal Disease, Chronic
Interventions: DEVICE: NIRS|BEHAVIORAL: Surgeon and patient satisfaction|OTHER: Pinprick Test|OTHER: Modified Bromage Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Efficacy and Mechanisms of a Novel Intervention for Chronic Pain Tailored to People Living With HIV
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Skills TO Manage Pain (STOMP)|BEHAVIORAL: comparison group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of PD-1 Monoclonal Antibody and HPV Vaccine in Patients With Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Neoplasms|Cervical Cancer|Cervical Neoplasms|Cervix Cancer
Interventions: DRUG: Sintilimab|DRUG: quadrivalent HPV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Venous Cannulation on the Incidence of Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: Bicaval cannulation|OTHER: Cavoatrial cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's Disease
Status: NOT_YET_RECRUITING
Conditions: Idiopathic Parkinson's Disease
Interventions: BIOLOGICAL: Aadipose-Derived Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Status: TERMINATED
Conditions: Injury of Anterior Cruciate Ligament
Interventions: DRUG: bupivacaine|DRUG: bupivacaine|DEVICE: continuous perineural infusion catheter|DEVICE: continuous perineural infusion catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oral Zinc Sulfate on Jaundice in Neonates Admitted to Neonatal Intensive Care Unit
Status: COMPLETED
Conditions: Serum Bilirubin
Interventions: DRUG: Zinc sulfate|OTHER: Placebo|OTHER: Phototherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: CMAB008 With MTX Therapy in Adult Patients With Moderately to Severely Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CMAB008|DRUG: MTX|DRUG: Remicade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarkers of Exposure and Biomarkers of Potential Harm in Adult Smokers Who Completely Switch to E-vapor Products
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: Experimental: Test Product 1|OTHER: Experimental: Test Product 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of the Therapy Tailored to Risk Factors in Treating Adult Patients (≤60) With Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: DAC|DRUG: CLAG|DRUG: Consolidation, I HAM cycle|DRUG: II Consolidation HiDAraC|DRUG: Consolidation, III HiDAraC cycle
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab, Nivolumab, and Talimogene Laherparepvec Before Surgery in Treating Participants With Localized, Triple-Negative or Estrogen Receptor Positive, HER2 Negative Breast Cancer-deleted
Status: TERMINATED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|HER2/Neu Negative|Invasive Ductal Carcinoma, Not Otherwise Specified|Progesterone Receptor Negative|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Nivolumab|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of Two Digital Devices for the Diagnosis of Neurocognitive Disorders in Elderly People With Cognitive Symptoms.
Status: RECRUITING
Conditions: Age-related Cognitive Decline|Computers, Handheld|Neurocognitive Disorders
Interventions: DIAGNOSTIC_TEST: COGNUM_ALZVR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Cooled Radiofrequency|DEVICE: Standard Radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of MK-217A/Alendronate Sodium 70-mg/Vitamin D3 5600 IU Combination Tablet (MK-0217A-329)
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: MK-217A/Alendronate Sodium 70-mg/Vitamin D3 5600 IU Combination Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impacts of Subsidized Ridesharing on Drunk Driving, Alcohol Consumption, and Mobility
Status: RECRUITING
Conditions: Driving Drunk|Alcohol Drinking
Interventions: BEHAVIORAL: ridesharing voucher|BEHAVIORAL: online shopping voucher
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Comparison of I-124 PET/CT, F-18 FDG PET/CT & I-123 Whole Body Scintigraphy for Recurrent Thyroid CA
Status: WITHDRAWN
Conditions: Thyroid Cancer
Interventions: DRUG: Iodine-124|DRUG: Iodine-123|DRUG: F-18 FDG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRKAd5 HIV-1 Gag Vaccine (V520) in Subjects With Chronic Hepatitis C (V520-022) (COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C
Interventions: BIOLOGICAL: MRKAd5 HIV-1 gag vaccine (V520)|BIOLOGICAL: Comparator: Placebo|BIOLOGICAL: Comparator: Open Label Tetanus and Diptheria Toxoids Adsorbed|BIOLOGICAL: MRKAd5 HIV-1 gag vaccine (V520)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Aripiprazole and Ziprasidone Among Schizophrenic Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Ziprasidone|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BurdEn of NEw Onset Atrial FIbrillation in patienTs With Acute Myocardial Infarction
Status: RECRUITING
Conditions: Atrial Fibrillation New Onset|Acute Myocardial Infarction
Interventions: DEVICE: Continuous Electronic Monitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With Stage IB, Stage II, or Stage IIIB Cervical Cancer
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: BIOLOGICAL: cetuximab|DRUG: cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy|Histology|Computer-aided Diagnosis|Artificial Intelligence|Colorectal Polyp|Adenoma Colon Polyp|Hyperplastic Polyp
Interventions: OTHER: AUTOMATED POLYP CLASSIFICATION
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficacy of Photodynamic Therapy for Femoral Artery Stenosis
Status: UNKNOWN
Conditions: Atherosclerotic Narrowing of the Superficial Femoral Artery|Atherosclerotic Occlusion of the Superficial Femoral Artery
Interventions: PROCEDURE: Delta amino leavulinic acid photodynamic therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Topical Antibiotic Prophylaxis for Eyelids
Status: COMPLETED
Conditions: Antibiotic Side Effect|Eyelid; Wound|Eyelid Diseases|Surgical Wound Infection|Surgical Wound, Recent|Surgical Incision|Skin Cancer Face|Antibiotic Allergy|Surgical Site Infection
Interventions: DRUG: Topical Antibiotic Product|DRUG: Topical Non-Antibiotic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction
Status: COMPLETED
Conditions: Adult Grade III Lymphomatoid Granulomatosis|Adult Nasal Type Extranodal NK/T-cell Lymphoma|Anaplastic Large Cell Lymphoma|Angioimmunoblastic T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Intraocular Lymphoma|Nodal Marginal Zone B-cell Lymphoma|Primary Central Nervous System Hodgkin Lymphoma|Primary Central Nervous System Non-Hodgkin Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Grade III Lymphomatoid Granulomatosis|Recurrent Adult Hodgkin Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Adult T-cell Leukemia/Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent Small Lymphocytic Lymphoma|Small Intestine Lymphoma|Splenic Marginal Zone Lymphoma|Stage III Adult Burkitt Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Adult Diffuse Mixed Cell Lymphoma|Stage III Adult Diffuse Small Cleaved Cell Lymphoma|Stage III Adult Hodgkin Lymphoma|Stage III Adult Immunoblastic Large Cell Lymphoma|Stage III Adult Lymphoblastic Lymphoma|Stage III Adult T-cell Leukemia/Lymphoma|Stage III Cutaneous T-cell Non-Hodgkin Lymphoma|Stage III Grade 1 Follicular Lymphoma|Stage III Grade 2 Follicular Lymphoma|Stage III Grade 3 Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage III Marginal Zone Lymphoma|Stage III Mycosis Fungoides/Sezary Syndrome|Stage III Small Lymphocytic Lymphoma|Stage IV Adult Burkitt Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Adult Diffuse Mixed Cell Lymphoma|Stage IV Adult Diffuse Small Cleaved Cell Lymphoma|Stage IV Adult Hodgkin Lymphoma|Stage IV Adult Immunoblastic Large Cell Lymphoma|Stage IV Adult Lymphoblastic Lymphoma|Stage IV Adult T-cell Leukemia/Lymphoma|Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma|Stage IV Grade 1 Follicular Lymphoma|Stage IV Grade 2 Follicular Lymphoma|Stage IV Grade 3 Follicular Lymphoma|Stage IV Mantle Cell Lymphoma|Stage IV Marginal Zone Lymphoma|Stage IV Mycosis Fungoides/Sezary Syndrome|Stage IV Small Lymphocytic Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific|Waldenström Macroglobulinemia
Interventions: DRUG: vorinostat|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy
Status: UNKNOWN
Conditions: Hepatic Encephalopathy|Hypertension, Portal|Liver Cirrhosis
Interventions: DRUG: Erythromycin|DRUG: Neomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Camel Whey Protein Gel for the Treatment of Aphthous Ulcer
Status: COMPLETED
Conditions: Aphthous Stomatitis, Recurrent|Antioxidative Stress
Interventions: COMBINATION_PRODUCT: placebo gel|COMBINATION_PRODUCT: camel whey protein gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Trial of NNC 0151-0000-0000 in Subjects With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Inflammation|Rheumatoid Arthritis
Interventions: DRUG: NNC 0151-0000-0000|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: BEHAVIORAL: HABIT Intervention|OTHER: Standard of Care|OTHER: Education materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Ambulatory Versus In-hospital Antibiotic Treatment in Children With Febrile Neutropenia
Status: COMPLETED
Conditions: Chemotherapy-Induced Febrile Neutropenia
Interventions: OTHER: Outpatient oral treatment.|OTHER: Inpatient intravenous treatment.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors
Status: TERMINATED
Conditions: Solid Tumor|Microsatellite Stable Colorectal Cancer|HPV Positive Oropharyngeal Squamous Cell Carcinoma|Cervical Cancer|Melanoma (Skin)|Cutaneous Squamous Cell Carcinoma|Mesothelioma|Renal Cell Carcinoma|Oropharynx Cancer
Interventions: BIOLOGICAL: TBio-6517|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Efficacy of an Enzyme Combination in Managing Knee Osteoarthritis Pain in Adults
Status: COMPLETED
Conditions: Wobenzym|Osteoarthritis
Interventions: DRUG: Diclofenac|DIETARY_SUPPLEMENT: Wobenzym|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lumbar Transforaminal Anterior Epidural Steroid Injections in Discogenic Low Back Pain
Status: UNKNOWN
Conditions: Degenerative Disc Disease|Low Back Pain
Interventions: DRUG: Dexamethasone-Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inetetamab Combined With Pyrotinib and Chemotherapy in the Treatment of HER2 Positive Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Inetetamab|DRUG: Pyrotinib|DRUG: Capecitabine|DRUG: Gemcitabine|DRUG: Vinorelbine|DRUG: Carboplatin|DRUG: Albumin paclitaxel|DRUG: Eribulin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Multiple Sclerosis (MS) Participants With the Use of Digital Technology (Smartphones and Smartwatches) - A Feasibility Study
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Smartphone and Smartwatch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Neuromuscular Blockade on Operating Conditions and Overall Satisfaction During Spinal Surgery
Status: COMPLETED
Conditions: Neuromuscular Blockade|Surgery|Anesthesia|Spinal Diseases
Interventions: DRUG: sufficient dose of rocuronium|DRUG: sugammadex 10 min after position change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer|Chronic Pain Due to Malignancy (Finding)
Interventions: DRUG: Sulfasalazine|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of 5 mg vs. 20 mg Desloratadine on Skin Lesions in Patients With Chronic Urticaria (CU)
Status: COMPLETED
Conditions: Chronic Urticaria
Interventions: DRUG: desloratadine|DRUG: desloratadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Cognitive Behavior Therapy for Depression, Stigmatization, Excessive Worries, and Emotional Management Among Women Facing Partner Violence
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Behaviour Therapy
Interventions: BEHAVIORAL: cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fall Prevention in Older Adults Study
Status: COMPLETED
Conditions: Accidental Fall|Postural Balance
Interventions: BEHAVIORAL: A Matter of Balance plus Dual-Task Balance Challenge Group|BEHAVIORAL: A Matter of Balance Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Early Whole Body Vibration and Progressive Resistance Training in Fast-Track Total Knee Arthroplasty.
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: PROCEDURE: Total Knee Arthroplasty|OTHER: Whole Body Vibration|OTHER: Progressive Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Water-based Zinc Intervention Trial in Zinc Deficient Children
Status: TERMINATED
Conditions: Zinc Deficiency|Diarrhea
Interventions: DEVICE: zinc enriching filter (LifeStrawFamily)|DEVICE: placebo filter|OTHER: disinfection tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Efficacy of Valganciclovir in Glioblastoma Patients
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Valganciclovir Tablets|DRUG: Temozolomide 120 mg|RADIATION: Radiotherapy 60 Gy|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brief Intervention Study for Quitting Smoking
Status: TERMINATED
Conditions: Smoking|Tobacco Use Cessation|Smoking Cessation
Interventions: BEHAVIORAL: Brief advice|BEHAVIORAL: Compact cessation course|BEHAVIORAL: Standard cessation course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: European (EU) Post Approval Study of the INCRAFT® AAA Stent Graft System in Subjects With Abdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysms
Interventions: DEVICE: Endovascular abdominal aortic aneurysm repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment
Status: COMPLETED
Conditions: AIDS-related Diffuse Large Cell Lymphoma|AIDS-related Diffuse Mixed Cell Lymphoma|AIDS-related Diffuse Small Cleaved Cell Lymphoma|AIDS-related Immunoblastic Large Cell Lymphoma|AIDS-related Lymphoblastic Lymphoma|AIDS-related Peripheral/Systemic Lymphoma|AIDS-related Primary CNS Lymphoma|AIDS-related Small Noncleaved Cell Lymphoma|Childhood Diffuse Large Cell Lymphoma|Childhood Immunoblastic Large Cell Lymphoma|HIV-associated Hodgkin Lymphoma|Leptomeningeal Metastases|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Medulloblastoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent/Refractory Childhood Hodgkin Lymphoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: topotecan hydrochloride|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effectiveness and Safety of Colon Capsule Endoscope System for Capturing and Viewing Colon Images
Status: COMPLETED
Conditions: Prospective Study
Interventions: DEVICE: PC-I and COLON2|DEVICE: COLON2 and PC-I
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Ascending Dose Study for AZD 7268 in Japanese Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD7268|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Epicondylar Muscle Activation in Tennis Players
Status: COMPLETED
Conditions: Epicondylitis, Lateral
Interventions: OTHER: Electrical dry needling + Conventional physiotherapy|OTHER: Dry needling + Conventional physiotherapy|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer With HRR Mutation and MSS
Status: UNKNOWN
Conditions: Gastric Cancer Stage IV
Interventions: DRUG: olaparib+pembrolizumab+paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension
Status: RECRUITING
Conditions: Scleroderma, Diffuse|Scleroderma, Systemic|Scleroderma, Limited|Sclerosis, Progressive Systemic|Skin Diseases|Connective Tissue Diseases|Pathologic Processes|Autoimmune Diseases
Interventions: DRUG: Oral Ifetroban|DRUG: Oral Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rates: The BASICS Trial
Status: WITHDRAWN
Conditions: Colposcopy
Interventions: OTHER: 2-1-1 United Way Healthy Missouri Hotline|OTHER: National Comprehensive Cancer Network (NCCN) Distress Thermometer|OTHER: Basic needs survey|OTHER: 2-1-1 survey|OTHER: Usual Care Reminder Call
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: REGulatory T Cells in Autism Induced by Maternal Immune Activation
Status: NOT_YET_RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: BIOLOGICAL: REGulatory T cells in Autism induced by maternal Immune activation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Education Impact on Rehabilitation of Hospitalized Patients With Chronic Obstructive Pulmonary Disease.
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Education program|OTHER: Pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using the ATC/DDD to Monitor Antibiotic Use at Lower Primary Care Facilities in Southwestern Uganda
Status: UNKNOWN
Conditions: ATC/DDD|Antibiotic Utilization
Interventions: BEHAVIORAL: ATC/DDD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Oxygenation Between Nasal PAP vs Nasal During Propofol-based Sedation for EUS
Status: TERMINATED
Conditions: Endoscopic Ultrasound
Interventions: DEVICE: SuperNO2VA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Remote Telemedicine Fetal Monitoring Feasibility Study
Status: NOT_YET_RECRUITING
Conditions: Pregnancy, High Risk|Telemonitoring|Telemedicine|Ultrasound|Cardiotocography
Interventions: DEVICE: Pregnabit Pro device and PregnaOne platform|DRUG: Pulsenmore device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study in Healthy Adults to Evaluate Effect of Food on Pharmacokinetics, Safety and Tolerability of ABT-450 With Ritonavir
Status: COMPLETED
Conditions: HCV Infection
Interventions: DRUG: ABT-450|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colonoscopy or Fecal Occult Blood Test in Screening Healthy Participants for Colorectal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: PROCEDURE: annual screening|PROCEDURE: fecal occult blood test|PROCEDURE: screening colonoscopy|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Augmented Efficacy of rPMS on the rTMS on Upper Limb Function in Patients With Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: DEVICE: rTMS+rPMS_iTBS_M|DEVICE: rTMS+rPMS_cTBS_M|DEVICE: rTMS+sham rPMS_M|DEVICE: rTMS+rPMS_iTBS_U|DEVICE: rTMS+rPMS_cTBS_U|DEVICE: rTMS+sham rPMS_U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Blood Storage Age on the Resolution of Lactic Acidosis in Children With Severe Malarial Anemia at Mulago Hospital
Status: COMPLETED
Conditions: Compare Blood Age for Transfusion
Interventions: BIOLOGICAL: Blood transfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Haemodynamics Variations of Transcutaneous Oxygen in Patient With Areterio-venous Leg Ulcers Under Venous Compression
Status: COMPLETED
Conditions: Leg Ulcer|Compression; Vein
Interventions: DEVICE: venous compression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IBI310 in Combination With Sintilimab in Patients With DNA Mismatch Repair Deficient (dMMR)/Microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: IBI310 (anti-CTLA-4 antibody)|BIOLOGICAL: Sintilimab(anti-PD-1 antibody)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Outcome of Respiratory Muscle Training in Stroke Patients
Status: COMPLETED
Conditions: Cerebrovascular Disorders
Interventions: OTHER: Respiratory muscle training for EMT+IMT|OTHER: Regular Rehabilitation|OTHER: Respiratory muscle training for EMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Six Month Clinical Trial Assessing Efficacy And Safety Of Inhaled Insulin In Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Inhaled human insulin (EXUBERA™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-coated Balloon Therapy for In-stent Restenosis and de Novo Coronary Lesions
Status: RECRUITING
Conditions: Coronary Heart Disease
Interventions: PROCEDURE: Pretreatment strategies before drug balloon therapy|PROCEDURE: Different types of in-stent restenosis were treated with drug-coated balloons
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DPNB vs. Modified DPNB With Ventromedial Infiltration (DPNB According to Dalens' Technique)
Status: COMPLETED
Conditions: Circumcision, Meatotomy or Distal Coronary Correction of Hypospadia
Interventions: PROCEDURE: Performing dorsal penile nerve block (DPNB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|STEMI
Interventions: DRUG: Chewing Ticagrelor LD|DRUG: Chewing Prasugrel LD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared to Tritanrix-HepB/Hib™ and OPV Given at Age 2, 4, and 6 Months.
Status: COMPLETED
Conditions: Diphtheria|Tetanus|Pertussis|Haemophilus Influenzae Type b|Hepatitis B
Interventions: BIOLOGICAL: DTaP-IPV-HB-PRP~T|BIOLOGICAL: Tritanrix-HepB/Hib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Codesign of an Optical Device to Measure Urine Flow and Volume
Status: NOT_YET_RECRUITING
Conditions: Urinary Incontinence|Urinary Retention|Urinary Tract Infections|Overactive Bladder|Benign Prostatic Hyperplasia|Underactive Bladder
Interventions: OTHER: Focus Group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma
Status: RECRUITING
Conditions: Oropharynx Cancer, Stage I
Interventions: BIOLOGICAL: Atezolizumab|PROCEDURE: Transoral Surgery with cervical lymphadenctomy (neck dissection)|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lower Back Treatment in People With Patellofemoral Pain Syndrome.
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Lumbopelvic Manipulation|OTHER: Passive lumbar spine flexion and extension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of PEA on Muscle Recovery Following Resistance Exercise
Status: COMPLETED
Conditions: Muscle Recovery|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: PEA|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Metformin in Children With Type 1 Diabetes
Status: COMPLETED
Conditions: Effect of Change in T1DM Glycemic Control
Interventions: DRUG: metformin|DRUG: Basal/bolus insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DOAC Versus VKA After Cardiac Surgery
Status: WITHDRAWN
Conditions: Anticoagulant-induced Bleeding
Interventions: DRUG: Warfarin|DRUG: Dabigatran|DRUG: Rivaroxaban|DRUG: Apixaban|DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dosage of Caffeine on Intraocular Pressure
Status: UNKNOWN
Conditions: Intraocular Pressure|Caffeine Dosage
Interventions: OTHER: decaffeinated coffee|OTHER: regular dose coffee|OTHER: high dose coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Prebiotics in Reducing Inflammation and Clinical Endpoints in Ulcerative Colitis (PRInCE-UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DIETARY_SUPPLEMENT: 2'-Fucosyllactose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Risedronate (Actonel), a Third Generation Bisphosphonate in Patients With Ankylosing Spondylitis: a Phase 2 Pilot Study
Status: COMPLETED
Conditions: Ankylosing Spondylitis
Interventions: DRUG: drug treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of High-flow Oxygen Therapy and Non-invasive Ventilation on Lung Volumes and on Upper Airway
Status: RECRUITING
Conditions: Respiratory Failure
Interventions: PROCEDURE: HFNC|PROCEDURE: NIV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Performance of the Kronos Electrocautery Device for Electrocautery Procedures Following Coaxial Biopsy Procedures
Status: COMPLETED
Conditions: Hepatic Disease|Renal Disease
Interventions: DEVICE: Kronos Electrocautery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Comparison of a Postbiotic-gel With Placebo Gel for Gingival Inflammation in Patients With Down Syndrome
Status: ENROLLING_BY_INVITATION
Conditions: Down Syndrome|Gingival Bleeding
Interventions: OTHER: Biorepair Plus Parodontgel Intensive|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery
Status: COMPLETED
Conditions: Name Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma|Stage II Oropharyngeal Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma|Stage III Laryngeal Squamous Cell Carcinoma|Stage III Oral Cavity Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IV Hypopharyngeal Squamous Cell Carcinoma|Stage IV Laryngeal Squamous Cell Carcinoma|Stage IV Oral Cavity Squamous Cell Carcinoma|Stage IV Oropharyngeal Squamous Cell Carcinoma|Stage IVA Hypopharyngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Squamous Cell Carcinoma|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Hypopharyngeal Squamous Cell Carcinoma|Stage IVB Laryngeal Squamous Cell Carcinoma|Stage IVB Oral Cavity Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma|Stage IVC Hypopharyngeal Squamous Cell Carcinoma|Stage IVC Laryngeal Squamous Cell Carcinoma|Stage IVC Oral Cavity Squamous Cell Carcinoma|Stage IVC Oropharyngeal Squamous Cell Carcinoma
Interventions: DRUG: Paclitaxel|DRUG: Carboplatin|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: In Vitro Fertilization (IVF) and Acupuncture for Infertility
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: acupuncture|PROCEDURE: IVF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy to Improve Myocardial Function in Patients Undergoing Coronary Artery Bypass Grafting (CABG)
Status: UNKNOWN
Conditions: Coronary Disease|Myocardial Infarction
Interventions: PROCEDURE: Bone Marrow Stem Cell Therapy combined CABG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent G-CSF in Patients With Breast Cancer Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide (TAC)
Status: TERMINATED
Conditions: Breast Cancer|Neutropenia|Febrile Neutropenia
Interventions: DRUG: Filgrastim|DRUG: Peg-filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)
Status: RECRUITING
Conditions: Lung Cancer|NSCLC
Interventions: DRUG: Atezolizumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of MPC-6827 and Temozolomide in Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: MPC-6827 + Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Periodontal Risk Communication in Patients With and Without History of Tooth Loss
Status: RECRUITING
Conditions: Periodontitis|Periodontal Diseases|Communication
Interventions: BEHAVIORAL: Test treatment|BEHAVIORAL: Control treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: amifostine trihydrate|DRUG: cisplatin|DRUG: cyclophosphamide|DRUG: vincristine sulfate|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MUSCLE EFFECTS OF NEUROMUSCULAR ELECTROSTIMULATION IN MECHANICALLY VENTILATED PATIENTS IN AN ICU
Status: NOT_YET_RECRUITING
Conditions: Intensive Care Unit Acquired Weakness
Interventions: DEVICE: neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of LEO 138559 in Healthy Subjects and Subjects With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: LEO 138559|DRUG: LEO 138559 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Rio Trial - ReoPro and Peripheral Arterial Intervention to Improve Clinical Outcome in Patients With Peripheral Arterial Disease
Status: UNKNOWN
Conditions: Arterial Occlusive Diseases
Interventions: PROCEDURE: Balloon Angioplasty|DRUG: ReoPro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Method of Maxilla Alveolar Process Reconstruction Using Synthetic Tricalcium Phosphate and Autologous MMSCs
Status: UNKNOWN
Conditions: Partially Edentulous Maxilla|Alveolar Bone Atrophy|Alveolar Bone Loss
Interventions: PROCEDURE: Oral mucosa biopsy|PROCEDURE: Sinus lift with implantation of tissue engineered construction|DEVICE: Dental implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ceftriaxone in the Management of Bipolar Depression
Status: TERMINATED
Conditions: Bipolar Depression
Interventions: DRUG: ceftriaxone|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Belimumab in Treating Symptomatic Waldenstroms Macroglobulinaemia
Status: UNKNOWN
Conditions: Symptomatic Waldenstroms Macroglobulinaemia
Interventions: DRUG: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: PROCEDURE: Stem cell transplantation|DRUG: Fludarabine|DRUG: Cyclophosphamide|DRUG: Etoposide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Methotrexate|DRUG: Cyclosporine|PROCEDURE: Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leveraging Home Health Aides to Improve Outcomes in Heart Failure
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Failure|Congestive Heart Failure
Interventions: BEHAVIORAL: mHealth app|BEHAVIORAL: Virtual training course
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DEVICE: Digital ACT|OTHER: Digital Symptom Tracker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally-Invasive Realtime Assessment of Continuous Lactate in Exercise
Status: UNKNOWN
Conditions: Exercise|Lactate
Interventions: DEVICE: Microneedle|DIAGNOSTIC_TEST: Blood lactate measurement|OTHER: Exercise regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY