pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Dose Escalation by Boosting Radiation Dose Within the Primary Tumor Using 18FDG-PET/CT for Unresectable Thoracic Esophageal Cancer
Status: UNKNOWN
Conditions: Esophageal Cancer
Interventions: RADIATION: Radiotherapy|DRUG: Chemotherapy (5-FU+DDP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Workplace Based Physiotherapy of Elderly-care Workers With Non-specific Neck Pain.
Status: RECRUITING
Conditions: Neck Pain
Interventions: OTHER: Electrical Stimulation Therapy|OTHER: Manual Therapy|OTHER: Exercise Therapeutic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Ledipasvir/Sofosbuvir Fixed-Dose Combination and Vedroprevir With or Without Ribavirin in Treatment-Experienced Participants With Chronic Genotype 1 HCV Infection and Cirrhosis
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: VDV|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard and Delayed FDG PET/CT After Chemoradiation Therapy in Assessing Patients With Metastatic Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Malignant Neoplasm in the Spine
Interventions: PROCEDURE: Computed Tomography|OTHER: Fludeoxyglucose F-18|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fluid Therapy During Brain Tumor Resection in Children
Status: COMPLETED
Conditions: Brain Neoplasms
Interventions: DRUG: balanced crystalloid solution (components: sodium chloride, sodium gluconate, sodium acetate, potassium chloride and magnesium chloride)|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tolerability and Potential ECG Effects After a Single Oral Dose of Pentoxyverine Citrate in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: pentoxyverine citrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis
Status: COMPLETED
Conditions: Lupus Nephritis
Interventions: DRUG: Mycophenolate mofetil|DRUG: Azathioprine|DRUG: Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Epothilone D in Combination With Herceptin (Trastuzumab) in Patients With HER-2 Positive Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Epothilone D|DRUG: Herceptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematological Cancer or Other Disease
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: BIOLOGICAL: anti-thymocyte globulin|DRUG: cyclophosphamide|DRUG: cyclosporine|DRUG: fludarabine phosphate|DRUG: mycophenolate mofetil|PROCEDURE: umbilical cord blood transplantation|RADIATION: total body irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immune Response of Intradermal and Intramuscular Preparations of Inactive Seasonal Influenza Vaccine in Older Age Group.
Status: COMPLETED
Conditions: Influenza, Human
Interventions: BIOLOGICAL: trivalent inactivated influenza
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Fractional CO2 Laser System (Fraxel Repair Laser) Intended for Treatment of Perioral Rhytides/Wrinkles
Status: COMPLETED
Conditions: Wrinkle
Interventions: PROCEDURE: Fraxel Laser Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Significant Coronary Artery Disease by Promising Biomarker: A2A Adenosine Receptor (A2AR) Assays
Status: UNKNOWN
Conditions: Chronic Coronary Syndromes
Interventions: BIOLOGICAL: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: B-Receptor Signaling in Cardiomyopathy
Status: COMPLETED
Conditions: Carcinomas|Amyloidosis|Anal Cancer|Anemia|Cholangiocarcinoma of the Extrahepatic Bile Duct|Transitional Cell Carcinoma of Bladder|Bone Marrow Transplant Failure|Bone Cancer|Cancer of Brain and Nervous System|Breast Cancer|Carcinoma of the Large Intestine|Endocrine Cancer|Esophageal Cancer|Eye Cancer|Gall Bladder Cancer|Gastric (Stomach) Cancer|Gastrooesophageal Cancer|Gastrointestinal Stromal Tumor (GIST)|Gynecologic Cancers|Head and Neck Cancers|Hepatobiliary Neoplasm|Kidney (Renal Cell) Cancer|Leukemia|Lung Cancer|Hodgkin Disease|Lymphoma, Non-Hodgkin|Mesothelioma|Multiple Myeloma|Myelodysplastic Syndromes (MDS)|Neuroendocrine Tumors|Myeloproliferative Disorders|Pancreatic Cancer|Prostate Cancer|Skin Cancer|Soft Tissue Sarcoma|Testicular Cancer|Thymus Cancer|Thyroid Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the PK/PD and Safety of TA-7284 in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: TA-7284 Low|DRUG: TA-7284 High
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Longer Interval of IVT IBI302 in Subjects With nAMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: dose 1 IBI302|DRUG: Aflibercept|BIOLOGICAL: dose 2 IBI302
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Weekly Gemcitabine in Combination With Infusional Fluorodeoxyuridine and Oral Calcium Leucovorin in Adult Cancer Patients
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: gemcitabine|DRUG: fluorodeoxyuridine|DRUG: leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Risks of Gastroesophageal Reflux in the Endotracheal Intubation or the I-gel
Status: UNKNOWN
Conditions: Gastroesophageal Reflux in Laparoscopy
Interventions: DEVICE: i-gel|DEVICE: endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Effect of HCQ on AnxA5 Resistance Assay in Antiphospholipid (aPL) Positive Patients With and Without Systemic Lupus Erythematosus (SLE)
Status: COMPLETED
Conditions: Antiphospholipid Syndrome|Thrombophilia Due to Antiphospholipid Antibody|Systemic Lupus Erythematosus
Interventions: OTHER: Phlebotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cannabidiol in Patients With COVID-19 and Cardiovascular Disease or Risk Factors
Status: TERMINATED
Conditions: COVID-19|Cardiovascular Diseases|Cardiovascular Risk Factor
Interventions: DRUG: Cannabidiol, pharmaceutically produced with < 5 ppm THC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: BI 671800 in Asthmatic Patients on Inhaled Corticosteroids
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: BI 671800|DRUG: Placebo|DRUG: Montelukast
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Study of Monoclonal Antibody Cocktail Being Tested for the Prevention of COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: DRUG: ADM03820|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Roxadustat Combined With Luspatercept Versus Luspatercept Monotherapy in the Treatment of Refractory MDS-RS
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Roxadustat|DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphoid Leukemia
Interventions: BIOLOGICAL: Acalabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Omalizumab in Adult and Adolescent Patients With Severe Persistent Allergic Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Omalizumab|OTHER: Optimized asthma therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Satisfaction of the New Pen Needle 33 Gauge x 4 mm.
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: Needle for insulin pen, 4 mm long and with a diameter of 33 gauge|DEVICE: Needle for insulin pen, 4 mm long and with a diameter of 32 gauge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Sevelamer Carbonate on Serum Trimethylamine-n-Oxide (TMAO) Level in Patients With Chronic Kidney Disease (CKD) Stage 3b-4
Status: UNKNOWN
Conditions: CKD Stage 3b|CKD Stage 4
Interventions: DRUG: Sevelamer Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation
Status: COMPLETED
Conditions: Esophagogastroduodenoscopy|Colonoscopy
Interventions: OTHER: Esophagogastroduodenoscopy and colonoscopy split dose prep|OTHER: Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep|OTHER: Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Epidural and Dorsal Root Stimulation in Humans With Spinal Cord Injury
Status: RECRUITING
Conditions: Spinal Cord Injuries|Paraplegia|Tetraplegia|Paralysis
Interventions: DEVICE: Percutaneous epidural and dorsal root stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessing The Long-Term Safety And To Explore The Long-Term Efficacy Of Zonisamide As Monotherapy In Newly Diagnosed Partial Seizures
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Zonisamide|DRUG: Carbamazepine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Full Bladder IUD Insertion Without Vulsellum Under Ultrasound Guidance
Status: NOT_YET_RECRUITING
Conditions: Contraceptive Device
Interventions: PROCEDURE: Vulsellum group|PROCEDURE: Ultrasound group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity of RSV Vaccines in Residents of Long-Term Care Facilities (LTCF)
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus (RSV)
Interventions: BIOLOGICAL: RSV vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Repetitive Transcranial Magnetic Stimulation of the Posterior Parietal Cortex in Patients Suffering From Gilles de la Tourette Syndrome
Status: TERMINATED
Conditions: Gilles de la Tourette Syndrome|Tics
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial
Status: NOT_YET_RECRUITING
Conditions: Polycythemia Vera (PV)|Essential Thrombocythemia (ET)|Myelofibrosis (MF)
Interventions: DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4SC-201 (Resminostat) and Sorafenib in Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: 4SC-201|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Breast Cancer|Endometrial Cancer|Head and Neck Cancer|Melanoma (Skin)|Ovarian Cancer|Sarcoma
Interventions: DRUG: BI 2536|OTHER: high performance liquid chromatography|OTHER: mass spectrometry|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Intravenous Versus Oral 5-HT3 Antagonists Combined With NK-1 Receptor Antagonists for the Prevention of CINV in Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Chemotherapy-induced Nausea and Vomiting
Interventions: DRUG: Aprepitant|DRUG: Palonosetron|DRUG: Fosaprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Acupuncture for Cerebral Vasospasm After Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: SAH (Subarachnoid Hemorrhage)|Cerebral Vasospasm
Interventions: DEVICE: acupuncture|DEVICE: Electroacupuncture|DEVICE: Intradermal acupuncture|DEVICE: Mock transcutaneous electrical nerve stimulation|DEVICE: sham intradermal acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enhanced Assistance During Radiotherapy for Unmet Essential Needs
Status: NOT_YET_RECRUITING
Conditions: Bone Cancer|Brain Cancer|Colorectal Cancer|Esophagus Cancer|Lymphoma|Salivary Gland Cancer|Head and Neck Cancer|Liver Cancer|Ovarian Cancer|Pancreatic Cancer|Prostate Cancer|Small Intestine Cancer|Stomach Cancer|Urinary Bladder Cancer|Anal Cancer|Blood Cancer|Breast Cancer|Cervical Cancer|Lung Cancer|Kidney Cancer|Penile Cancer|Skin Cancer|Testicular Cancer|Thyroid Cancer|Uterine Cancer|Vaginal Cancer|Vulvar Cancer
Interventions: OTHER: Standard assistance|OTHER: Enhanced assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Primary and Booster Vaccination Study With Pneumococcal Vaccine GSK1024850A and Prophylactic Antipyretic Treatment
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: GSK1024850A (SynflorixTM)|BIOLOGICAL: Infanrix hexa|BIOLOGICAL: Infanrix-IPV/Hib|DRUG: Ibuprofen|DRUG: Paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)
Status: COMPLETED
Conditions: HBV|Chronic HBV Infection
Interventions: DRUG: TAF|DRUG: TDF|DRUG: TAF Placebo|DRUG: TDF Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Megestrol Acetate in Severe Chronic Obstructive Pulmonary Disease With Loss of Weight
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Megestrol acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Added Value of a Rehabilitation Brace in the Treatment at Home After a Fracture of the Ankle
Status: WITHDRAWN
Conditions: Fracture of the Ankle
Interventions: DEVICE: Use of a rehabilitation brace instead of a plaster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Profile of CKD-333
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: CKD-333 formulation I|DRUG: CKD-333 formulation II|DRUG: CKD-330+D086
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Evaluation of Safety, Tolerability, and Efficacy of XT-150 for the Treatment of Osteoarthritic Pain
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: XT-150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of [18F]MNI-1126 as an Imaging Marker for Synaptic Density Loss
Status: COMPLETED
Conditions: Alzheimer Disease|Parkinson Disease|Healthy Volunteers
Interventions: DRUG: [18F]MNI-1126
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Do the Symptoms of Chronic Constipation Improve With a Primary Care Programme Based on Behavioural Re-education and Abdominal Massage?
Status: ACTIVE_NOT_RECRUITING
Conditions: Constipation Chronic Idiopathic
Interventions: BEHAVIORAL: change of habits|OTHER: change of habits + auto abdominal massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing N-terminal-proB-type Natriuretic Peptide With Other Criteria in Pleural Fluid Analysis
Status: RECRUITING
Conditions: Pleural Effusion|Heart Failure|Malignant Neoplasm|Fluid Overload|Hypoalbuminemia|Renal Failure|Cirrhosis|Infections
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rituxan in Churg Strauss Syndrome With Renal Involvement
Status: TERMINATED
Conditions: Churg-Strauss Syndrome
Interventions: DRUG: Rituximab|DRUG: Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Injections by Nurses and Physicians Compared
Status: COMPLETED
Conditions: Eye Diseases
Interventions: PROCEDURE: intravitreal injections given by a nurse|PROCEDURE: intravitreal injections given by a physician|PROCEDURE: Intravitreal injections|DRUG: Anti-VEGF agents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety of Concurrent Durvalumab With CRT Followed by Durvalumab for Chinese Unresectable Stage III NSCLC
Status: UNKNOWN
Conditions: Unresectable Stage III NSCLC
Interventions: DRUG: Durvalumab|DRUG: Carboplatin/ Paclitaxel|DRUG: Pemetrexed/ Cisplatin|DRUG: Pemetrexed/ Carboplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Post-Cesarean Section Acupressure on the Severity of Pain and First Mobilization Distance
Status: COMPLETED
Conditions: Pain|Mobilization
Interventions: OTHER: Acupressure|OTHER: Plasebo acupressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity
Status: COMPLETED
Conditions: Mouth Neoplasms
Interventions: DRUG: Celecoxib|DRUG: Calcitriol|DRUG: Celecoxib plus Calcitriol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Frozen-thawed Embryo Transfers and Fresh Embryo Transfers With Whole Chromosome Analysis Using Next Generation Sequencing
Status: UNKNOWN
Conditions: Infertility
Interventions: OTHER: PGD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Study to Investigate the Safety, Tolerability and Efficacy of YH4808 in Patients With Reflux Esophagitis
Status: COMPLETED
Conditions: Reflux Esophagitis
Interventions: DRUG: Esomeprazole 40mg|DRUG: YH4808 A mg|DRUG: YH4808 B mg|DRUG: YH4808 C mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.
Status: RECRUITING
Conditions: Endometriosis|Chronic Pain|Women's Health
Interventions: OTHER: therapeutic-educational physiotherapy and pain education program|OTHER: pain education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Th1, Th2 and Th17 Cytokines on the Success of Embryo Implantation (ImmuNoFertilité)
Status: RECRUITING
Conditions: Assisted Reproduction
Interventions: BIOLOGICAL: Unique blod sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of Azelaic Acid (AzA) 15% in Topical Treatment of Mild to Moderate Perioral Dermatitis
Status: COMPLETED
Conditions: Perioral Dermatitis
Interventions: DRUG: Azelaic acid 15% gel|DRUG: Non-active base from azelaic acid 15% gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Recurrence and Metastasis in Genetically High-Risk Melanomas
Status: WITHDRAWN
Conditions: Malignant Melanoma
Interventions: DRUG: Fluvastatin|OTHER: RNA-sequencing|OTHER: Gene expression profiling
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Deep BLock on Intraoperative Surgical Conditions
Status: COMPLETED
Conditions: Prostate Hypertrophy|Renal Disease
Interventions: DRUG: Surgical block (rocuronium; atracurium/mivacurium)|DRUG: Surgical block (rocuronium; atracurium/mivacurium)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Two Tacrolimus-based Immunosuppressant Regimens and Induction With Thymoglobulin in Kidney Transplants From Deceased Donors With Expanded Criteria
Status: COMPLETED
Conditions: Kidney Transplantation|Cytomegalovirus
Interventions: DRUG: Induction therapy with Thymoglobulin, prednisone, everolimus and late introduction of tacrolimus|DRUG: Induction therapy with Thymoglobulin, prednisone, mycophenolate sodium and late introduction of tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effects Of Progressive Relaxation Techniques Along With Benson Relaxation Techniques
Status: RECRUITING
Conditions: Postpartum Disorder
Interventions: OTHER: Progressive relaxation techniques|OTHER: Benson relaxation techniques
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Dual-Task Timed Up and Go Test (Cognitive) and 3-m Backwards Walk Test
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Dual-Task Timed Up and Go Test (cognitive)|OTHER: 3-m Backward Walk Test|OTHER: Modified Four Square Step Test|OTHER: Timed Up and Go Test|OTHER: Berg Balance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Efficacy and Safety Evaluation of HCP1904-2 in Essential Hypertension Patients
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: HCP1904-2|DRUG: RLD2001-2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reirradiation and Niraparib in Patients With Recurrent Glioblastoma
Status: WITHDRAWN
Conditions: Recurrent Glioblastoma
Interventions: DRUG: Niraparib|RADIATION: Re-irradiation (re-RT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of CIN-107 in Adults With Primary Aldosteronism
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Aldosteronism|Hyperaldosteronism
Interventions: DRUG: CIN-107 2 mg dosing|DRUG: CIN-107 4 mg dosing|DRUG: CIN-107 8 mg dosing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Choices4Health: Intervention to Prevent Substance-exposed Pregnancy
Status: COMPLETED
Conditions: Prenatal Alcohol Exposure|Prenatal Tobacco Exposure|Prenatal Marijuana Exposure
Interventions: BEHAVIORAL: Computer tablet-delivered C4H|BEHAVIORAL: Person-delivered C4H|BEHAVIORAL: Brief Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Citicoline on Brain Function and Behavior in Marijuana-Dependent Individuals
Status: COMPLETED
Conditions: Marijuana Abuse
Interventions: DRUG: citicoline|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Tilt Test-Induced REsponse in Closed-loop Stimulation (TIRECS) Study
Status: COMPLETED
Conditions: Syncope, Vasovagal, Neurally-Mediated
Interventions: DEVICE: Closed-loop Stimulation on first|DEVICE: Closed-loop Stimulation off first
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin, Fludarabine, Cytarabine, and Rituximab in Patients With Richter's Transformation and Leukemias
Status: COMPLETED
Conditions: Richter's Transformation|Leukemia
Interventions: DRUG: Oxaliplatin|DRUG: Fludarabine|DRUG: Cytarabine|DRUG: Rituximab|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Lemon Verbena Extract Supplementation in Sub-ADHD Children
Status: COMPLETED
Conditions: Behavior, Child|Cognitive Change
Interventions: DIETARY_SUPPLEMENT: Lemon verbena|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Interferon and GM-CSF Compared With Imatinib Mesylate and Vaccine Therapy in Patients With Chronic Phase CML on a TKI
Status: COMPLETED
Conditions: Leukemia
Interventions: BIOLOGICAL: GM-K562 cell vaccine|BIOLOGICAL: Interferon alfa|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ECoG BMI for Motor and Speech Control
Status: RECRUITING
Conditions: ALS|SCI - Spinal Cord Injury|Stroke|Multiple Sclerosis|Muscular Dystrophies
Interventions: DEVICE: PMT/Blackrock Combination Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease on Hemodialysis
Status: COMPLETED
Conditions: Hyperparathyroidism, Secondary
Interventions: DRUG: Etelcalcetide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: eHealth Partnered Evaluation Initiative - Evaluation of the Initial Deployment of VA's Annie Texting System
Status: COMPLETED
Conditions: Hepatitis C
Interventions: OTHER: Annie text messaging system|OTHER: Annie text messaging system with Usual implementation|OTHER: Annie text messaging system with Augmented implementation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery
Status: COMPLETED
Conditions: Postoperative Pulmonary Complications
Interventions: PROCEDURE: Thoracic Paravertebral Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Selumetinib in Treating Patients With Papillary Thyroid Cancer That Did Not Respond to Radioactive Iodine
Status: COMPLETED
Conditions: Recurrent Thyroid Gland Carcinoma|Stage I Thyroid Gland Papillary Carcinoma|Stage II Thyroid Gland Papillary Carcinoma|Stage III Thyroid Gland Papillary Carcinoma|Stage IV Thyroid Gland Papillary Carcinoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol or Sevoflurane Anesthesia in Egyptian Patients
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone-coached "Graphic Narrative" Bibliotherapy for Dementia Caregivers
Status: NOT_YET_RECRUITING
Conditions: Dementia Caregiver|Depressive Symptoms|Caregiving Appraisal
Interventions: OTHER: Telephone coached graphic narrative bibliotherapy|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Status: COMPLETED
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic|Ice Pick Scars|Rolling Scars|Boxcar Scars
Interventions: DEVICE: HCC_45
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine, Cyclophosphamide and Etoposide for Minimal Residual Disease Positive Acute Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia
Interventions: DRUG: Clofarabine|DRUG: Etoposide|DRUG: Cyclophosphamide|BIOLOGICAL: allogeneic hematopoietic cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity According to Coronary Microvascular Dysfunction and Body Composition
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction (HFpEF)
Interventions: DIAGNOSTIC_TEST: Adenosine stress echocardiography with the evaluation of coronary artery blood flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Snack Consumption on Energy Intake in Preschoolers
Status: ACTIVE_NOT_RECRUITING
Conditions: Energy Intake|Snacks|Children, Preschool
Interventions: BEHAVIORAL: Snacking|BEHAVIORAL: No Snacking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Copper on the Healing of Obstetric Wounds
Status: COMPLETED
Conditions: Cesarean Section; Infection|Perineal Infection|Wound Infection|Surgical Site Infection
Interventions: OTHER: Copper impregnated wound dressing|OTHER: Normal wound dressing|OTHER: Copper impregnated maternity pads|OTHER: Normal maternity pads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer
Status: TERMINATED
Conditions: Colorectal Cancer|Appendiceal Cancer|Peritoneal Carcinoma
Interventions: DRUG: Oxaliplatin|DRUG: mFOLFIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of High Dose Intravenous (IV) Ascorbic Acid in Measurable Solid Tumor Disease
Status: SUSPENDED
Conditions: Sarcoma|Adenocarcinoma|Carcinoma|Multiple Myeloma|Desmoplastic Small Round Cell Tumor
Interventions: DRUG: Ascorbic acid (vitamin C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies
Status: TERMINATED
Conditions: Immune and Microbial Reconstitution|Systemic Viral Infection|Acute-graft-versus-host Disease|Chronic Graft-versus-host-disease|Recurrent Malignancy|Cytokine Release Syndrome|Allogenic Related Donors|Cell Therapy/Immunotherapy Patients
Interventions: DIAGNOSTIC_TEST: Blood Sample|DIAGNOSTIC_TEST: Stool Sample|DIAGNOSTIC_TEST: Urine Sample|DIAGNOSTIC_TEST: Bronchoalveolar Lavage (BAL) fluid|DIAGNOSTIC_TEST: Gastrointestinal biopsy x 2-4|DIAGNOSTIC_TEST: Skin biopsy|DIAGNOSTIC_TEST: Skin, mouth, and/or ocular swab|DIAGNOSTIC_TEST: Apheresis Product|DIAGNOSTIC_TEST: Final cellular product
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: PK and Safety Study of HCP1102, HGP0813 and HGP1408
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: montelukast and levocetirizine FDC|DRUG: Singulair + xyzal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Swallowing Disorders in Geriatrics Studied With Respiratory Plethysmography by Inductance
Status: COMPLETED
Conditions: Swallowing Disorders
Interventions: DEVICE: respiratory plethysmography by inductance
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Reward Sensitivity and Pharmacotherapy for Smoking Cessation
Status: ACTIVE_NOT_RECRUITING
Conditions: Tobacco Use Cessation
Interventions: DRUG: Varenicline|DRUG: Nicotine Patch|DRUG: Placebo Patch|DRUG: Placebo Tablet|BEHAVIORAL: Questionnaires|BEHAVIORAL: Counseling Sessions|OTHER: Lab Session|OTHER: Saliva Test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Motor Stroke Recovery Using Patient-tailored Non-invasive Brain Stimulation
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Sham TDCS|DEVICE: Anodal TDCS|DEVICE: Cathodal TDCS|DEVICE: Magnetic Resonance Imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Analysis of Myocardial Uptake of Bone Radiopharmaceuticals in Patients With Cardiac ATTR Amyloidosis
Status: UNKNOWN
Conditions: Amyloidosis Transthyretin
Interventions: DIAGNOSTIC_TEST: Whole-body & CZT bone tracer imaging (SPECT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Percutaneous Intramedullary K-wires Fixation of Pediatric Shaft Both Bone Forearm Fractures
Status: RECRUITING
Conditions: Fracture Fixation, Intramedullary|Fracture Forearm
Interventions: PROCEDURE: K-wires Fixation of Pediatric Shaft Both Bone Forearm Fractures
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intraoperative VR for Older Patients Undergoing TKA
Status: RECRUITING
Conditions: Total Knee Arthroplasty
Interventions: OTHER: Virtual Reality Immersive Relaxation|OTHER: Immersive Audio Experience|OTHER: Sham Virtual Reality Experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of IV Iron Isomaltoside on Postoperative Anemia in Total Knee Arthroplasty Patients
Status: COMPLETED
Conditions: Anemia|Knee Arthropathy
Interventions: DRUG: Iron Isomaltoside 1000
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-Blind, Dose-Escalation, Placebo-Controlled Phase I Clinical Trial Investigating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Oral Doses of HRS-7085 Tablets in Healthy Subjects, With Assessment of Food Effects
Status: NOT_YET_RECRUITING
Conditions: Inflammatory Bowel Disease
Interventions: DRUG: HRS-7085 Tablets|DRUG: HRS-7085 simulant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Project to Promotion of Breastfeeding
Status: COMPLETED
Conditions: Breast Feeding
Interventions: OTHER: Brief Motivational Intervention|OTHER: Breastfeeding education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Oxytocin and Pain Sensitivity and Threshold
Status: WITHDRAWN
Conditions: Pain
Interventions: DRUG: Intranasal Oxytocin|DRUG: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma
Interventions: DRUG: Orelabrutinib|DRUG: Pomalidomide|DRUG: Rituximab|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study Evaluating the Safety and Efficacy of Esomeprazole in Treatment of Non-alcoholic Steatohepatitis
Status: RECRUITING
Conditions: Fatty Liver Disease|Steatohepatitis, Nonalcoholic
Interventions: DRUG: Esomeprazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Pharmacokinetics of BI 113608 in Healthy Asian and Caucasian Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 113608|DRUG: Placebo|DRUG: BI 113608|DRUG: Placebo|DRUG: BI 113608|DRUG: BI 113608|DRUG: BI 113608|DRUG: BI 113608
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trial of Imatinib (Gleevec®) in Selected Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: DRUG: Imatinib (Gleevec)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TELI TAD - Telithromycin in Tonsillitis in Adolescents and Adults
Status: TERMINATED
Conditions: Tonsillitis|Pharyngitis
Interventions: DRUG: Telithromycin|DRUG: Penicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Abuse
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Spirit-Only Motivational Interviewing|OTHER: Self-Change
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Antitussive Effects of FP01 Lozenges in Subjects With Cough Due to Upper Respiratory Tract Infection
Status: COMPLETED
Conditions: Acute Cough
Interventions: DRUG: FP01
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: V501 Immunogenicity Study in Females Age 9 to 17 Years (V501-028)
Status: COMPLETED
Conditions: HPV Infections
Interventions: BIOLOGICAL: Quadrivalent Human Papillomavirus (Types 6, 11, 16, 18) Recombinant Vaccine (V501)|BIOLOGICAL: Comparator: Placebo (unspecified)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Carbon Ions Boost Followed by Pelvic Photon Radiotherapy for High Risk Prostate Cancer
Status: RECRUITING
Conditions: Adenocarcinoma of Prostate
Interventions: RADIATION: Carbon Ions Boost Followed by Pelvic Photon Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PH
Status: COMPLETED
Conditions: Heart Failure, Diastolic|Pulmonary Hypertension
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study in Patients With Chronic Kidney Disease and Healthy Volunteers
Status: COMPLETED
Conditions: Kidney Disease
Interventions: DRUG: Propranolol|DRUG: Losartan|DRUG: Eprosartan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Study to Evaluate the Erythropoietic Response in Hepatitis C Virus (HCV) Patients Receiving Combination Ribavirin (RBV)/Interferon (IFN) Therapy or RBV/PEG IFN (NATURAL HISTORY-HCV)
Status: COMPLETED
Conditions: Hepatitis C|Anemia
Interventions: DRUG: Pegylated Interferon and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acellular Dermis in Rotator Cuff Repair
Status: COMPLETED
Conditions: Rotator Cuff Tears|Rotator Cuff Injuries
Interventions: DEVICE: acellular dermis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of S-1 and Capecitabine on Coronary Artery Blood Flow
Status: TERMINATED
Conditions: Esophagus Cancer|Stomach Cancer|Small Bowel Cancer|Colon Cancer|Rectum Cancer
Interventions: DRUG: S-1|DRUG: Capecitabine|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Mimicking Diet (FMD) in Conjunction With Chemotherapy in Advanced Ovarian Cancer
Status: NOT_YET_RECRUITING
Conditions: Ovarian Cancer|Chemotherapeutic Toxicity
Interventions: DIETARY_SUPPLEMENT: Fasting Mimicking Diet (Xentigen by L'Nutra)|DRUG: Carboplatin|DRUG: Paclitaxel|DIETARY_SUPPLEMENT: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resistant Starch on Glucose and Insulin Sensitivity in Individuals With Type 2 Diabetes
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Resistant Starch Type 4-Raw|DIETARY_SUPPLEMENT: Resistant Starch Type 4-Raw|DIETARY_SUPPLEMENT: Resistant Starch Type 4-Cooked|DIETARY_SUPPLEMENT: Resistant Starch Type 4-Cooked|DIETARY_SUPPLEMENT: Shredded Wheat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of CB03-154 in Healthy Participants in Australia
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: CB03-154|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Percutaneous Biliary Drainage Versus Endoscopic Ultrasound-guided Biliary Drainage
Status: RECRUITING
Conditions: Bile Duct Obstruction, Extrahepatic
Interventions: PROCEDURE: US-guided percutaneous biliary drainage|PROCEDURE: EUS-guided biliary drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT