pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Genetic and Brain Mechanisms of Naltrexone's Treatment Efficacy for Alcoholism
Status: COMPLETED
Conditions: Alcohol Dependence
Interventions: DRUG: Naltrexone 50 Mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Glycopyrronium bromide 25ug|DRUG: Placebo|DRUG: Glycopyrronium bromide 12.5ug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS Effects in the Neuromodulation and Pain Threshold of Chronic Myofascial Pain Patients
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine Hydrochloride With or Without WEE1 Inhibitor AZD1775 in Treating Patients With Previously Untreated Pancreatic Cancer That Is Metastatic or Cannot Be Removed by Surgery
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma|Stage III Pancreatic Cancer AJCC v6 and v7|Stage IV Pancreatic Cancer AJCC v6 and v7|Unresectable Pancreatic Carcinoma
Interventions: DRUG: AZD1775|DRUG: Gemcitabine|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ticagrelor in Post-transplant Patients With Pediatric Hepatic Artery Thrombosis (HAT)
Status: UNKNOWN
Conditions: Hepatic Artery Thrombosis|Liver Transplant; Complications|Pediatric Disease
Interventions: DRUG: Ticagrelor Oral Tablet [Brilinta]|DRUG: Low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DFDBA and Amniotic Membrane in the Treatment of Periodontal Osseous Defects
Status: UNKNOWN
Conditions: Periodontal Intrabony Defects
Interventions: PROCEDURE: OFD+ DFDBA|PROCEDURE: OFD+ DFDBA+ AM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
Status: RECRUITING
Conditions: Stroke|Intracranial Atherosclerotic Stenosis (ICAS)
Interventions: OTHER: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of RO6807952 in Patients With Diabetes Mellitus Type 2
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Placebo|DRUG: RO6807952
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Waldenstrom Macroglobulinemia|Mantle Cell Lymphoma|Marginal Zone Lymphoma|B-cell Lymphoma|Small Lymphocytic Lymphoma
Interventions: DRUG: Pirtobrutinib|DRUG: Venetoclax|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Thalidomide in the Adjuvant Treatment of Moderate New Coronavirus (COVID-19) Pneumonia
Status: UNKNOWN
Conditions: COVID-19 Thalidomide
Interventions: DRUG: thalidomide|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Agreement Between Oxygen Saturation Measured by Two Probes in Infants on the Neonatal Unit
Status: COMPLETED
Conditions: Neonatal Disease
Interventions: DEVICE: Oxygen saturation probe Mindray 520 N and Mindray 521 N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessments and Interventions for Hand Neuropathy in DM
Status: COMPLETED
Conditions: Diabetes Mellitus|Neuropathy, Diabetic
Interventions: OTHER: Biofeedback training|OTHER: Home-based tendon gliding and resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacological Modulation of Hippocampal Activity in Psychosis 2
Status: COMPLETED
Conditions: Schizophrenia; Psychosis
Interventions: DRUG: Levetiracetam (LEV) 500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Compare Safety and Efficacy of HX575 Epoetin Alfa and US-licensed Epoetin Alfa
Status: COMPLETED
Conditions: Anemia|Chronic Kidney Disease (CKD)
Interventions: DRUG: HX575 epoetin alfa|DRUG: US-licensed epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Activity and Cerebral Metabolism in the Elderly: a Randomised Controlled Trial
Status: COMPLETED
Conditions: Dementia|Cognitive Impairment
Interventions: OTHER: Individualised aerobic exercise training|OTHER: Waiting Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Visuospatial and Affective Abilities in Parkinson Disease
Status: NOT_YET_RECRUITING
Conditions: Parkinson Disease|Alexithymia|Visuospatial/Perceptual Abilities
Interventions: OTHER: Prismatic adaptation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Resistance Training Based on Gamification in Children Aged 10-12 Years Old During Physical Education
Status: NOT_YET_RECRUITING
Conditions: Muscular Fitness
Interventions: OTHER: RT Functional HIIT circuit program (15 minutes) with or without gamification approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Knowing and Remembering: Cognitive and Neural Influences of Familiarity on Recognition Memory in Early Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: OTHER: Neuropsychological tests|DEVICE: A cranial MRI|OTHER: Experimental procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT
Status: UNKNOWN
Conditions: Hereditary Hemorrhagic Telangiectasia|Epistaxis
Interventions: DRUG: Mupirocin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study In Adolescent And Adult Subjects 12 Years Of Age And Older With Seasonal Allergic Rhinitis To Assess Onset of Action
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal
Interventions: DRUG: GW685698X Aqueous Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Single Dose Antenatal Corticosteroids (SNACS) for Women at Risk of Preterm Birth
Status: COMPLETED
Conditions: Preterm Birth|Complication of Prematurity|Obstetric Labor, Premature|Obstetric Labor Complications|Pregnancy Complications
Interventions: DRUG: 12 mg betamethasone + placebo|DRUG: 24 mg betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Collagen Peptide Supplementation and Physical Exercise in Older Adults
Status: COMPLETED
Conditions: Collagen Supplementation|Physical Exercise Training
Interventions: DIETARY_SUPPLEMENT: Collagen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vaccine Therapy in Treating Patients With Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: NY-ESO-1 peptide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Methylphenidate on the Cognitive Function of Older People With Mild Cognitive Impairment
Status: TERMINATED
Conditions: Mild Cognitive Impairment (MCI)
Interventions: DRUG: Methylphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Utilizing Wearable Device to Observe the Clinical Response of COPD Patients Treated With Combined Bronchodilator and Home-based Pulmonary Rehabilitation Program
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Indacaterol/Glycopyrronium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Testing a Behavioral Intervention to Incorporate Advances in HIV Prevention for Black Young MSM in Alabama
Status: RECRUITING
Conditions: HIV/AIDS
Interventions: BEHAVIORAL: Adapted Brothers Saving Brothers (aBSB)|BEHAVIORAL: Standard Street Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Treatment With Sofosbuvir (SOF) and Ledipasvir (LDV) to Prevent HCV Recurrence After Liver Transplantation (OLT)
Status: TERMINATED
Conditions: Hepatitis C Viral Infection
Interventions: DRUG: Sofosbuvir (SOF) and Ledipasvir (LDV)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost of a Quantitative and Qualitative Nutritional Supplementation in Elderly Patients
Status: TERMINATED
Conditions: Denutrition
Interventions: DIETARY_SUPPLEMENT: Renutryl 500|DIETARY_SUPPLEMENT: Generique|DIETARY_SUPPLEMENT: Generique + Renutryl 500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells Therapy in Patients With Recent Intracerebral Hemorrhage
Status: COMPLETED
Conditions: Hemorrhagic Stroke|Intracerebral Hemorrhage
Interventions: BIOLOGICAL: MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Covid-19 Aerosol Box On Intubation Success Rate
Status: COMPLETED
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Intubation using aerosol box|DEVICE: Intubation without aerosol box
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Two Iodinated Contrast Agents in Renally Impaired Patients Undergoing Cardiac Angiography
Status: COMPLETED
Conditions: CIN
Interventions: DRUG: Iopamidol 370 mgI/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Comparative Study of Dietary and Immunological Management of Refractory Epilepsy in Children
Status: UNKNOWN
Conditions: Refractory Epilepsy
Interventions: DRUG: RiTUXimab Injection [Rituxan]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A "Less-rapid" Sequence Anesthetic Induction/Intubation Sequence? Does Apneic Oxygenation by Means of an Oxygenating Laryngoscope Blade Prolong the "Duration of Apnea Without Desaturation" in Paralyzed Non-obese and Morbidly Obese Patients?
Status: WITHDRAWN
Conditions: Apneic Oxygenation
Interventions: DEVICE: Apneic oxygenation: Eight minute|DEVICE: Without apneic oxygenation|DEVICE: Apneic oxygenation: five minutes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions
Status: ACTIVE_NOT_RECRUITING
Conditions: Postbariatric Hypoglycemia
Interventions: DRUG: Mizagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Identification of Airway Structures Necessary for Airway Access Via the Skin
Status: COMPLETED
Conditions: Upper Airway Obstruction
Interventions: BEHAVIORAL: identification of the airway by from the cranial end|BEHAVIORAL: identification of the airway from the distal end
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase 1 Study of TT-00920 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: TT-00920|DRUG: TT-00920 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sickle Cell Disease (SCD) Decision Aid
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: OTHER: Qualitative Interviews Decisional Needs Assessment|OTHER: Sickle Cell Decision Aid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Point-of-care (POC) Viral Load (VL) Testing During Pregnancy in Zimbabwe
Status: COMPLETED
Conditions: HIV Infections
Interventions: DEVICE: Point-of-care (POC) viral load (VL) testing plus refresher training|OTHER: Standard of care central laboratory VL testing plus refresher training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Fear Conditioned Response in Healthy Subjects and in OCD Patients Pre and Post Treatment With Sertraline.
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Sertraline Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of Temporomandibular Joint Arthroscopy With Botulinum Toxin Injection Versus Placebo
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: DRUG: Incobotulinumoxin A|PROCEDURE: TMJ surgical arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia
Status: UNKNOWN
Conditions: Vascular Stiffness|Hypotension on Induction|Anesthesia; Reaction
Interventions: DIAGNOSTIC_TEST: bioimpedance spectroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety of TY027, a Treatment for COVID-19, in Humans
Status: COMPLETED
Conditions: Coronavirus Disease-2019 (COVID-19)
Interventions: BIOLOGICAL: TY027|OTHER: 0.9% Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Ocular Safety and Tolerability of Eye Drops Containing Prednisolone Acetate in Patients With Intraocular Inflammation After Cataract Surgery
Status: COMPLETED
Conditions: Cataract Surgery
Interventions: DRUG: Prednisolone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Algology in Oncology Osteopathic Support (ALGOS)
Status: RECRUITING
Conditions: Breast Cancer|Neuropathic Pain
Interventions: OTHER: Osteopathic treatment|OTHER: Capsaicin QUTENZA Patch (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Compare Laser Assisted New Attachment Procedure (LANAP) to Traditional Treatments of Chronic Periodontitis
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DEVICE: LANAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 99mTc-3PRGD2 SPECT/CT in Esophagus Cancer Patients
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: 99mTc-3PRGD2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Gut Microbiome Restoration on Primary Hypertension Via FMT
Status: UNKNOWN
Conditions: Hypertension
Interventions: BIOLOGICAL: FMT capsules|OTHER: Placebo capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transtympanic Gentamicin vs. Steroids in Refractory Meniere's Disease
Status: COMPLETED
Conditions: Meniere's Disease
Interventions: DRUG: Methylprednisolone|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate Efficacy and Safety of ANT-301 in Patients With Knee Osteoarthritis in Grade III/IV by K/L
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: BIOLOGICAL: ANT-301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on the Effects of ILARIS® on Patients With Proliferative Diabetic Retinopathy (PDRP)
Status: TERMINATED
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: CANAKINUMAB (ILARIS®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Computer Attention Training Programs in Schools for Children With Attention Deficit/Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Neurofeedback|BEHAVIORAL: Cognitive Training|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PF-06372865 in Subjects With Photosensitive Epilepsy
Status: COMPLETED
Conditions: Reflex Epilepsy, Photosensitive
Interventions: DRUG: PF-06372865|DRUG: Placebo|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis
Status: COMPLETED
Conditions: Rectal Cancer
Interventions: DRUG: folfox|RADIATION: short course Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST
Status: COMPLETED
Conditions: Renal Cell Cancer|Colorectal Cancer|GIST
Interventions: OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Validation of Self-administered Questionnaire for Assessing Calcium Intake in Patients With Multiple Sclerosis or Chronic Inflammatory Arthritis
Status: COMPLETED
Conditions: Multiple Sclerosis|Rheumatoid Arthritis
Interventions: OTHER: QALCIMUM questionnaire|OTHER: Determination of calcium intake by a dietician interview
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Lymph Node Mapping in Finding Metastatic Disease in Patients With Sebaceous Gland Cancer of the Eyelid
Status: COMPLETED
Conditions: Eyelid Sebaceous Gland Carcinoma
Interventions: PROCEDURE: Lymph Node Mapping|PROCEDURE: Sentinel Lymph Node Biopsy|DRUG: Technetium Tc-99m Sulfur Colloid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Assessment of the Anesthetic Effect on the Activity of Immune Cell in Patient With Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: propofol group|DRUG: sevoflurane group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Trial of Crenolanib in Subjects With D842V Mutated GIST
Status: UNKNOWN
Conditions: GIST With D842V Mutated PDGFRA Gene
Interventions: DRUG: Crenolanib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-emptive Analgesic Administration in Primary Tooth Extraction
Status: COMPLETED
Conditions: Local Anesthesia|Tooth Extraction
Interventions: DRUG: Acetaminophen|DRUG: Placebo|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Safety and Efficacy of New Dosage Schedule for Dietressa Drug in Treatment of Obese Patients
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Dietressa|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Lactobacillus Rhamnosus GG Vs. Placebo in Elderly Subjects Receiving Trivalent Inactivated Influenza Vaccine
Status: COMPLETED
Conditions: Healthy|Elderly
Interventions: BIOLOGICAL: Lactobacillus rhamnosus GG ATCC 53103 (LGG)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Antithymocyte Globulin, Clofarabine, and Rituximab in Treating Patients After an Unsuccessful Stem Cell Transplant
Status: TERMINATED
Conditions: Cancer
Interventions: BIOLOGICAL: anti-thymocyte globulin|BIOLOGICAL: rituximab|DRUG: clofarabine|PROCEDURE: stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Dosing Interval and Optimal Dose of AYP-101 for the Reduction of Submental Fat in Chin Area
Status: COMPLETED
Conditions: Moderate or Severe Submental Fullness
Interventions: DRUG: Polyene Phosphatidylcholine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of CRYOBEAUTY MAINS ET DECOLLETE Versus Liquid Nitrogen Cryotherapy, in the Treatment of Solar Lentigines
Status: COMPLETED
Conditions: Solar Lentigo
Interventions: DEVICE: CRYOBEAUTY MAINS ET DECOLLETE|DEVICE: Liquid nitrogen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma
Status: COMPLETED
Conditions: Open-Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: DuoTrav (travoprost-timolol ophthalmic drops)|DRUG: Xalacom (latanoprost-timolol ophthalmic drops)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple-dose Study in Chinese Subjects to Evaluate Safety,Tolerability,PK and PD of ZM-H1505R
Status: COMPLETED
Conditions: Healthy Volunteers|Hepatitis B, Chronic
Interventions: DRUG: ZM-H1505R|OTHER: ZM-H1505R Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer
Status: COMPLETED
Conditions: Neurotoxicity|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DIETARY_SUPPLEMENT: vitamin E|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subconjunctival Bevacizumab Effect on Bleb Vascularity
Status: UNKNOWN
Conditions: Bleb Vascularity|Bleb Fibrosis|Trabeculectomy Failure
Interventions: DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tranilast as a Radiosensitizer in Reradiation of Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Recurrent Cancer
Interventions: DRUG: Tranilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Urinary Proteomics Combined With Home Blood Pressure Telemonitoring for Health Care Reform
Status: NOT_YET_RECRUITING
Conditions: Protein Deregulation|Blood Pressure|Health Care Utilization|Cost Effectiveness|Patient Empowerment
Interventions: DIAGNOSTIC_TEST: In-vitro urinary diagnostic test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of Breakthrough Cancer Pain: Assessment of Fentanyl Buccal Tablets Titration and Treatment in Opioid-Tolerant Patients
Status: TERMINATED
Conditions: Cancer Pain|Breakthrough Pain
Interventions: DRUG: Fentanyl Buccal Tablet (FBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Short-term Effects of a Carob Snack on Postprandial Glycemic Responses and Energy Intake and Satiety
Status: COMPLETED
Conditions: Potential Abnormality of Glucose Tolerance|Appetite; Lack or Loss, Nonorganic Origin
Interventions: OTHER: Glucose as reference food|OTHER: White bread as reference food|OTHER: Carob snack as test food|OTHER: Chocolate cookie snack as test food|OTHER: Carob preload|OTHER: Chocolate cookie preload
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Primary Prophylaxis for Spontaneous Bacterial Peritonitis
Status: TERMINATED
Conditions: Decompensated Cirrhosis|Small Bowel Bacterial Overgrowth Syndrome
Interventions: DRUG: Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Immediate Pain Relieving Effects of Sinbaro-3 for Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain With Radiculopathy|Low Back Pain Without Radiculopathy|Herniated Intervertebral Disc
Interventions: DRUG: Sinbaro-3|DRUG: Hwangryun
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an ACT and PBS Group for Parents and Education Staff
Status: COMPLETED
Conditions: Intellectual Disabilities With Other Behavioral Symptoms|Acceptance Processes|Psychological Distress|Burnout, Professional|Self Efficacy
Interventions: OTHER: ACT and PBS group workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia
Status: COMPLETED
Conditions: Affective Disorders|Psychotic Disorder
Interventions: BEHAVIORAL: progressive muscle relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Theophylline Treatment for Pseudohypoparathyroidism
Status: RECRUITING
Conditions: Pseudohypoparathyroidism|Albright Hereditary Osteodystrophy
Interventions: DRUG: Theophylline|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Highdose Nicotine Patch Therapy for Smokeless Tobacco Use
Status: COMPLETED
Conditions: Smokeless Tobacco Use
Interventions: DRUG: nicotine replacement therapy (nicotine patches)|DRUG: placebo NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma
Status: COMPLETED
Conditions: Scleroderma|Interstitial Lung Disease
Interventions: DRUG: dabigatran etexilate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Cardiovascular and Renal Effects of Moringa Oleifera Extracts and Stevia Rebaudiana Bertoni in Patients With Type II Diabetes Mellitus
Status: COMPLETED
Conditions: Benefits of a Capsules of Moringa Oleifera and Stevia Rebaudiana Bertoni in Patients With Type 2 Diabetes Mellitus Before and After 45 Days of add-on Therapy
Interventions: DIETARY_SUPPLEMENT: MOROLSTEVER1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD)
Status: COMPLETED
Conditions: Treatment Resistant Depression|Depressive Disorder, Treatment-Resistant|Depression, Bipolar
Interventions: DEVICE: SCC DBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study Comparing Topical M518101 and Vitamin D3 in Adult Psoriasis Patients
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: M518101
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neuromodulation for Central Post-stroke Pain: Mechanism, Safety and Outcome
Status: RECRUITING
Conditions: Central Post-stroke Pain|CPSP
Interventions: DEVICE: MCS surgery for CPSP|DEVICE: Vc-DBS surgery for CPSP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dexmedetomidine to Postoperative Awakening and Extubation-related Changes in Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Dexmedetomidine|OTHER: Saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Compound Danshen Dripping Pills on Diabetic Patients With Coronary Microcirculation Disturbance
Status: UNKNOWN
Conditions: Diabetes
Interventions: DRUG: Compound Danshen Dropping Pills|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Passive Descent in Obese Nulliparous Gravidae
Status: UNKNOWN
Conditions: Management of the Second Stage of Labor in Obese Nulliparous Women by Either Passive Descent or Immediate Pushing.
Interventions: PROCEDURE: Passive Descent|PROCEDURE: Pushing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety Study
Status: UNKNOWN
Conditions: Melanoma|TOR Serine-Threonine Kinases|Neoplasm Metastasis
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lithium and Divalproex for the Treatment of Comorbid Rapid Cycling Bipolar Disorder and Substance Abuse Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium|DRUG: Divalproex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 2 of 7)
Status: COMPLETED
Conditions: Exposure to Man-made Visible Light
Interventions: OTHER: Visible light exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of an Accelerated Infusion Rate of Daratumumab in Patients With Relapsed and Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma in Relapse
Interventions: DRUG: Daratumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Status: RECRUITING
Conditions: Hidradenitis Suppurativa
Interventions: DRUG: Eltrekibart|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment
Status: COMPLETED
Conditions: Breakthrough Pain|Pain Due to Certain Specified Procedures|Pain|Cancer|Terminal Disease
Interventions: PROCEDURE: Mobilization|PROCEDURE: Positioning|PROCEDURE: Personal Hygiene Care|PROCEDURE: Bladder catheterization|PROCEDURE: Wound care|PROCEDURE: Subcutaneous drugs administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
Status: COMPLETED
Conditions: Chronic Migraine, Headache|Temporomandibular Joint Dysfunction|Chronic Pain|Quality of Life|Sleep|Headache
Interventions: OTHER: Detection of Pain, Quality of Life, Sleep and Functioning|OTHER: Temporomandibular joint dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: BIOLOGICAL: 4 mL injection of Ampion|DRUG: 4 mL Injection of Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BI 695500 vs Rituxan First Line Treatment in Patients With Low Tumor Burden Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma, Non-Hodgkin
Interventions: DRUG: Rituximab|DRUG: BI 695500
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Role of IL5 in Epithelial Cell Integrity
Status: RECRUITING
Conditions: Chronic Rhinosinusitis With Nasal Polyps|Chronic Rhinosinusitis (Diagnosis)
Interventions: DRUG: Mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oseltamivir Pharmacokinetics in Morbid Obesity
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: OTHER: Patients with a BMI < 30 given Oseltamivir|OTHER: Patients with a BMI > 40 given Oseltamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart Disease
Status: COMPLETED
Conditions: Cardiomyopathy
Interventions: OTHER: Cardiac magnetic resonance sequence T1 mapping
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Computer Scan Based Analysing System on Improving Stroke Management Quality Evaluation
Status: RECRUITING
Conditions: Acute Ischemic Stroke and Transient Ischemic Attacks
Interventions: BEHAVIORAL: the response of KPI and corresponding suggestion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Synbiotic Treatment of Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: Synbiotic (Synergy1/B. longum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Positive Expiratory Pressure Devices in Stable COPD Patients
Status: WITHDRAWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DEVICE: Pulmonica|DEVICE: RC-Cornet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease
Status: RECRUITING
Conditions: Mesenchymal Stromal Cells|Cornea|Corneal Defect|Corneal Epithelium Defect
Interventions: BIOLOGICAL: MSC Secretome Eye Drops
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Vaccine Boosters in Patients With CKD
Status: TERMINATED
Conditions: Chronic Kidney Diseases|COVID-19
Interventions: BIOLOGICAL: Pfizer-BioNTech COVID-19 Vaccine|BIOLOGICAL: MODERNA SARS-CoV-2 Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent B-Cell Non-Hodgkin Lymphoma|Recurrent Chronic Lymphocytic Leukemia|Recurrent Diffuse Large B-Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Lymphoplasmacytic Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Refractory B-Cell Non-Hodgkin Lymphoma|Refractory Diffuse Large B-Cell Lymphoma|Refractory Follicular Lymphoma|Refractory Lymphoplasmacytic Lymphoma|Refractory Mantle Cell Lymphoma|Refractory Transformed Non-Hodgkin Lymphoma|Recurrent Transformed B-Cell Non-Hodgkin Lymphoma|Recurrent Transformed Chronic Lymphocytic Leukemia|Refractory Marginal Zone Lymphoma|Refractory Transformed B-Cell Non-Hodgkin Lymphoma|Refractory Transformed Chronic Lymphocytic Leukemia|Recurrent Small Lymphocytic Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Small Lymphocytic Lymphoma|Recurrent Central Nervous System Lymphoma|Refractory Central Nervous System Lymphoma
Interventions: BIOLOGICAL: Chimeric Antigen Receptor T-Cell Therapy|DRUG: Cyclophosphamide|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Leukapheresis|DRUG: Fludarabine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Identify if OVR Health's VR-Kit is Safe to Use and Helps to Improve Focus, Attention and Reduce Worry & Rumination.
Status: COMPLETED
Conditions: Anxiety|Depression, Anxiety
Interventions: DEVICE: OVR Health's VR experience
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Clinical Efficacy of Nail Brace for Treatment of Ingrown Toenails
Status: UNKNOWN
Conditions: Ingrown Nail
Interventions: DEVICE: Podofix nail brace|DEVICE: Combiped nail brace|DEVICE: Podofix and then Combiped nail brace
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LevineConservationModelandColorectalPatients
Status: NOT_YET_RECRUITING
Conditions: Fatigue|Peripheral Neuropathy|Anxiety
Interventions: BEHAVIORAL: Sensory ball, progressive relaxation exercise, training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of a Dolutegravir-based Regimen for the Initial Management of HIV Infected Adults in Resource-limited Settings
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Dolutegravir 50 mg|DRUG: Tenofovir disoproxil fumarate 300 mg / lamivudine 300 mg|DRUG: Efavirenz 400 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does the Use of Fiasp vs. Asp Lead to the Prolonged TIR in Children With Type 1 Diabetes?
Status: UNKNOWN
Conditions: Diabetes type1|Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin faster aspart (Fiasp, Novo Nordisk)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving the Mental Health and Well Being of Healthcare Providers Through the Transcendental Meditation Technique
Status: COMPLETED
Conditions: Burnout|Insomnia|Well Being
Interventions: BEHAVIORAL: Transcendental Meditation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Versus Late Lactoferrin in Prevention of Neonatal Sepsis
Status: COMPLETED
Conditions: Neonatal Sepsis
Interventions: DRUG: Lactoferrin|DRUG: Placebo (for Lactoferrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: IMPRoving Outcomes in Vascular DisEase- Aortic Dissection
Status: RECRUITING
Conditions: Type B Aortic Dissection
Interventions: PROCEDURE: TEVAR|OTHER: Guideline directed medical therapy and surveillance of dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Fed-Fast Pharmocokinetics and Bioequivalance of 300mg Capsules of Droxidopa
Status: COMPLETED
Conditions: Symptomatic Neurogenic Orthostatic Hypotension
Interventions: DRUG: Droxidopa|DRUG: Droxidopa|DRUG: Droxidopa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
Status: RECRUITING
Conditions: Brain Cancer|Glioma
Interventions: PROCEDURE: MRI and advanced MRI sequences
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Adult Solid Neoplasm
Interventions: DRUG: Ixabepilone|OTHER: Pharmacological Study|DRUG: Temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Scans in Diagnosing Primary or Recurrent Cervical Cancer in Patients Who Are Undergoing Surgery
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: PROCEDURE: biopsy|PROCEDURE: computed tomography|PROCEDURE: positron emission tomography|RADIATION: fludeoxyglucose F 18
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Recursive Self-feedback on Speech Production in Aphasia
Status: NOT_YET_RECRUITING
Conditions: Aphasia|Stroke
Interventions: BEHAVIORAL: Adaptive recursive self-feedback procedure|BEHAVIORAL: Non-adaptive recursive self-feedback procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dolutegravir Compared to Darunavir/Ritonavir , Each in Combination With Dual Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in ART-naive Subjects
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus
Interventions: DRUG: dolutegravir 50 mg OAD|DRUG: darunavir 800mg OAD|DRUG: ritonavir 100mg OAD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT