pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Resin Infiltratration on the Sealing of Proximal Early Caries
Status: UNKNOWN
Conditions: Tooth; Lesion, White Spot Lesions
Interventions: OTHER: ICON|BEHAVIORAL: instruction oral hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Extinction Learning in Youth With Tourette Syndrome
Status: COMPLETED
Conditions: Tourette Syndrome in Children|Tourette Syndrome in Adolescence|Habit Reversal Training|Tic
Interventions: BEHAVIORAL: Habit Reversal Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alpha Lipoic Acid on the Incidence and Severity of Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients
Status: UNKNOWN
Conditions: Radiation-Induced Mucositis
Interventions: DRUG: Alpha Lipoic Acid 600 MG Oral Tablets|OTHER: Placebo tablets|RADIATION: radiation or concurrent chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumors, KRAS Mutation
Interventions: DRUG: BI 1823911|DRUG: BI 1701963|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML
Status: RECRUITING
Conditions: AML|Acute Myeloid Leukemia|AML, Adult Recurrent|AML, Adult
Interventions: BIOLOGICAL: CD123/CD33 CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of SI-6603 in Patients With Lumbar Disc Herniation
Status: COMPLETED
Conditions: Intervertebral Disc Disease|Lumbar Disc Disease
Interventions: DRUG: Condoliase|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hu14.18-Interleukin-2 Fusion Protein in Treating Patients With Advanced Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: hu14.18-IL2 fusion protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breaking Implicit Bias Habits: An Individuation Pilot Study In Rheumatology
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus|Rheumatoid Arthritis|Inflammatory Arthritis|Osteoarthritis
Interventions: BEHAVIORAL: Individuation Intervention plus implicit bias educational modules|OTHER: Implicit bias educational modules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparing Perioperative Education Modalities for ACL Reconstruction on Patient Satisfaction, Self-Efficacy, and Surgical Outcomes
Status: RECRUITING
Conditions: ACL Injury|Anterior Cruciate Ligament Injuries
Interventions: BEHAVIORAL: Video-Based Intervention|BEHAVIORAL: Classroom-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Role of Bifidobacterium Intervention in Food Allergic Infants
Status: RECRUITING
Conditions: Food Allergy in Infants
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium M-16V|OTHER: allergy food avoidance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ubiquinol (Reduced COQ10) for Patients With Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: DRUG: Ubiquinol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Reducing Burden in Care Partners of Community-Dwelling Persons With Dementia and Oropharyngeal Dysphagia
Status: NOT_YET_RECRUITING
Conditions: Caregiver Burden|Alzheimer Disease|Dementia|Oropharyngeal Dysphagia
Interventions: BEHAVIORAL: WeCareToFeedDysphagia web tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin|DRUG: Insulin BIAsp30 (Novolog 70/30)|DRUG: Repaglinide|DRUG: Placebo-Metformin|DRUG: Placebo-Repaglinide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peripheral Vascular Effects of Sulfhydryl-containing Antihypertensive Pharmacotherapy on Microvessels in Humans
Status: TERMINATED
Conditions: Hypertension,Essential
Interventions: DRUG: Captopril Pill|DRUG: Enalapril Pill|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.
Status: UNKNOWN
Conditions: Veterans|TBI|Alcoholism|Irritable Mood
Interventions: DRUG: Medication Trial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Post-Market Study to Evaluate Adverse Event Incidence Rates in Patients With Skin of Color Undergoing Correction of Nasolabial Folds With Hylaform, Hylaform Plus and Captique.
Status: COMPLETED
Conditions: Facial Wrinkles
Interventions: DEVICE: Hylaform, Hylaform Plus (hylan B gel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Two Doses of Avaxim® 80U Pediatric (Inactivated Hepatitis A Vaccine) in Toddlers, Children and Adolescents
Status: COMPLETED
Conditions: Hepatitis A|Hepatitis A Virus
Interventions: BIOLOGICAL: Avaxim 80U Pediatric: Inactivated Hepatitis A Virus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Neonatal Wireless Monitoring System for Intensive Care
Status: UNKNOWN
Conditions: Preterm Infant|Infant, Newborn|Low; Birthweight, Extremely (999 Grams or Less)
Interventions: DEVICE: Wireless vital sign monitoring - comparative|DEVICE: Wireless vital sign monitoring - usability
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Oral Camostat Compared With Standard Supportive Care in Mild-Moderate COVID-19 Patients
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Camostat Mesilate|DRUG: Placebo|OTHER: Standard of Care Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abstinence Reinforcement Therapy (ART) for Rural Veteran Smokers
Status: COMPLETED
Conditions: Veteran|Smoking Cessation
Interventions: BEHAVIORAL: Abstinence Reinforcement Therapy (ART)|BEHAVIORAL: Telephone Counseling and NRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Relevance of the Antimicrobial Resistance Testing in the Treatment of Chronic Wounds With Antiseptics
Status: WITHDRAWN
Conditions: Decubiti|Chronic Wounds|Acute Wounds
Interventions: DRUG: Octenisept and Serasept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of LUM-201 in Children Who Have Previously Completed the LUM-201-01 Trial (OraGrowtH213)
Status: ACTIVE_NOT_RECRUITING
Conditions: Growth Hormone Deficiency
Interventions: DRUG: LUM-201
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning in Patients With Carotid Artery Stenosis Receiving Carotid EndArterectomy
Status: RECRUITING
Conditions: Carotid Artery Stenosis
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma
Status: UNKNOWN
Conditions: Malignant Melanoma|Neoplasm Metastasis
Interventions: GENETIC: investigational drug INGN 241
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Tibolone Treatment on the Endometrium
Status: COMPLETED
Conditions: Postmenopause|Osteoporosis
Interventions: DRUG: Tibolone|DRUG: Estradiol|DRUG: Estradiol + Medroxy Progesterone Acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized Smartphone-assisted Coaching System to Improve Glucose Homeostasis in Adults With Prediabetes - Main Study
Status: WITHDRAWN
Conditions: Prediabetes|Hyperglycemia|Postprandial Hyperglycemia|Impaired Glucose Tolerance|Impaired Fasting Glucose
Interventions: OTHER: Sweetch App & DBWS|OTHER: Sweetch App Alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Tolerability, Efficacy and Mucosal Inflammation Associated With Orally Administered Colon Cleansing for Colonoscopy
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Colonlytely|DRUG: Picolax/Picoprep|DRUG: Fleet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Selective Transvenous Chemoembolization of Primary Pancreatic Tumors
Status: WITHDRAWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Retrograde venous infusion of gemcitabine/lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Expression Profile of ERK5 and PKM2 Kinases in Neuroinflammatory Diseases.
Status: WITHDRAWN
Conditions: Sclerosis, Multiple|Guillain-Barre Syndrome|Inflammation
Interventions: BIOLOGICAL: Blood sample and Cerebrospinal fluid (CSF) collection.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Surgery With or Without Radiofrequency Ablation Followed by Irinotecan in Treating Patients With Colorectal Cancer That is Metastatic to the Liver
Status: COMPLETED
Conditions: Colorectal Cancer|Metastatic Cancer
Interventions: DRUG: irinotecan hydrochloride|PROCEDURE: adjuvant therapy|PROCEDURE: conventional surgery|PROCEDURE: radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of Vasopressors on the Anti Xa Response to Enoxaparin in Critically Ill Patients
Status: COMPLETED
Conditions: Venous Thrombosis|Critical Illness
Interventions: DRUG: Enoxaparine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS
Status: UNKNOWN
Conditions: COPD Exacerbation|Trauma
Interventions: DEVICE: Automated oxygen administration - FreeO2|OTHER: Standard administration of oxygen flow
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma or Other B-cell Cancers
Status: UNKNOWN
Conditions: Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: sargramostim|DRUG: cyclophosphamide|DRUG: melphalan|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Psychotherapy for Bipolar II Depression, Pilot Study, Phase II
Status: COMPLETED
Conditions: Bipolar II Disorder
Interventions: BEHAVIORAL: Interpersonal and Social Rhythm Therapy (IPSRT-BPII)|DRUG: Seroquel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lokelma for RAAS Maximisation in CKD & Heart Failure.
Status: RECRUITING
Conditions: Chronic Kidney Diseases|Heart Failure With Reduced Ejection Fraction|Hyperkalemia|ACE Inhibitor Induced Hyperkalaemia|Mineralocorticoid Resistant Hyperkalemia
Interventions: DRUG: Lokelma Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Status: COMPLETED
Conditions: Blood Loss, Surgical
Interventions: OTHER: Equal ratio ventilation(ERV)|OTHER: I:E Ratio "1:2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tanezumab In Osteoarthritis Of The Knee (2)
Status: COMPLETED
Conditions: Arthritis|Osteoarthritis
Interventions: BIOLOGICAL: tanezumab 10 mg|BIOLOGICAL: tanezumab 5 mg|DRUG: naproxen|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Improving the Selection of Patients With Glioblastoma Multiforme for Treatment With Epidermal Growth Factor Receptor Inhibitor Therapies
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: protein expression analysis|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunohistochemistry staining method
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets Combined With Standard Treatment/ Standard Treatment in Patients With Suspected and Mild Novel Coronavirus Pneumonia (COVID-19)
Status: UNKNOWN
Conditions: Novel Coronavirus Pneumonia|2019-nCoV
Interventions: DRUG: Bromhexine Hydrochloride Tablets|DRUG: Arbidol Hydrochloride Granules|DRUG: Recombinant Human Interferon α2b Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Tramadol in Prevention of Postpartum Depression
Status: COMPLETED
Conditions: Caesarean Section
Interventions: DRUG: Tramadol|DRUG: Hydromorphone|DRUG: Ropivacaine (Epidural analgesia)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Anti-PD-1/PD-L1 Antibody Plus Apatinib as Second-Line Treatment of Advanced Esophageal Squamous Cell
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Apatinib+ SHR-1210（Camrelizumab）|DRUG: Apatinib+ SHR-1316（Adebrelimab）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Oxycyte in Patients With Traumatic Brain Injury (TBI)
Status: TERMINATED
Conditions: Traumatic Brain Injury
Interventions: DRUG: Oxycyte|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of TopClosure(C)System in Healing Complicated Pacemaker Wounds
Status: UNKNOWN
Conditions: Wounds and Injuries
Interventions: DEVICE: TopClosure(c) System|DEVICE: Pressure Bandage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Postoperative BMI Changes and Functional Outcomes in Knee and Hip Arthroplasty
Status: COMPLETED
Conditions: Arthropathy|Obesity
Interventions: PROCEDURE: Total Knee Arthroplasty|PROCEDURE: Total Hip arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiovascular Clinical Project to Evaluate the Regenerative Capacity of CardioCell in Patients With Acute Myocardial Infarction (AMI)
Status: COMPLETED
Conditions: Myocardial Infarction
Interventions: DRUG: Cardiac Drug|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)
Status: COMPLETED
Conditions: Hypercholesterolemia|Atherosclerosis
Interventions: DRUG: Ezetimibe + Simvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of Full Pulpotomy Using Calcium Silicate Based Materials
Status: ACTIVE_NOT_RECRUITING
Conditions: Carious Teeth
Interventions: PROCEDURE: MTA pulpotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Is Real-time CGM Superior to Flash Glucose Monitoring
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DEVICE: Continuous Glucose Monitoring Guardian Connect Mobile system (real-time continuous glucose monitoring)|DEVICE: Continuous Glucose Monitoring FreeStyle Libre Flash system (intermittently-scanned continuous glucose monitoring)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mycosis Culture Collection From Dermatological Isolated
Status: ACTIVE_NOT_RECRUITING
Conditions: Onychomycosis|Resistant Infection|Nail Diseases
Interventions: DRUG: Terbinafine Topical Gel|DRUG: Itraconazole 200 mg|DRUG: Terbinafine 250 mg|DRUG: Ciclopirox Topical Gel|DRUG: Amorolfine 50 MG/ML
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Knee Bracing for People With Patellofemoral Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Patellofemoral realigning knee brace|DEVICE: Non-aligning knee brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transplantation of Fecal Microbiota for Clostridium Difficile Infection
Status: UNKNOWN
Conditions: Clostridium Difficile Infection
Interventions: PROCEDURE: Fecal Microbiota transplantation.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes on Pain and Range of Motion by the Use of Kinesio Taping in Subjects With Myofascial Trigger Point
Status: COMPLETED
Conditions: Mobility Limitation|Myofascial Trigger Point Pain
Interventions: DEVICE: Kinesio Taping|DEVICE: Sham Kinesio Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mindfulness-Based Cognitive Therapy Postpartum Mothers Stress, Postpartum Blues, Mother-Baby Attachment and Breastfeeding
Status: COMPLETED
Conditions: Mindfulness-based Cognitive Therapy
Interventions: OTHER: Mindfulness-Based Cognitive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Effect of Treatment With Bendamustine in Combination With Rituximab on QT Interval in Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Mantle Cell Lymphoma
Interventions: DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Bupivacaine-infused Fibrin Sealant Application on Post-tonsillectomy Pain & Hemorrhage
Status: TERMINATED
Conditions: Pain, Postoperative|Postoperative Hemorrhage
Interventions: DRUG: Bupivacaine|BIOLOGICAL: Fibrin Sealant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patency and Safety of the Drug Eluting Covered Biliary Stent Comparing to the Common Covered Biliary Stent
Status: COMPLETED
Conditions: Biliary Stricture|Malignant Neoplasms
Interventions: DEVICE: Biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating the Bioequivalence of Levonorgestrel/Ethinyl Estradiol Combinations in Cycling Women
Status: WITHDRAWN
Conditions: Contraception
Interventions: DRUG: Levonorgestrel/Ethinyl Estradiol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supporting Effect of Dronabinol on Behavioral Therapy in Fibromyalgia and Chronic Back Pain
Status: COMPLETED
Conditions: Fibromyalgia|Back Pain
Interventions: BEHAVIORAL: Operant behavioral treatment; Drug: THC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Suppression of Cutaneous Allergic Responses and Pruritis by Topical Minocycline
Status: UNKNOWN
Conditions: Allergic Rhinitis|Asthma
Interventions: DRUG: Minocycline Topical|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Comparator: rosuvastatin 5 mg + ezetimibe 10 mg|DRUG: Comparator: rosuvastatin 10 mg|DRUG: Comparator: rosuvastatin 10 mg + ezetimibe 10 mg|DRUG: Comparator: rosuvastatin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Minimal Invasive Versus Traditional Transgluteal Approach in Total Hip Arthroplasty: a Comparative Gait Analysis
Status: COMPLETED
Conditions: Total Hip Arthroplasty
Interventions: PROCEDURE: minimally invasive total hip arthroplasty|PROCEDURE: standard approach total hip arthroplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stereotactic Management of Arrhythmia - Radiosurgery in Treatment of Ventricular Tachycardia
Status: COMPLETED
Conditions: Ventricular Tachycardia
Interventions: RADIATION: Cardiac Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety and Efficacy of Teriflunomide (HMR1726) in Multiple Sclerosis With Relapses
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: teriflunomide (HMR1726)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of Peginterferon Alfa-2a (Pegasys) and Adeforvir Dipivoxil (ADV) in Participants With Lamivudine-Resistant Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis B
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Adefovir dipivoxil|DRUG: Lamivudine|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Statins and Lupus: Effects of Statins on Clinical Lupus Parameters, Serological Markers and Toll-like Receptors
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascertaining Diagnosis Classification With Elicited Speech
Status: COMPLETED
Conditions: Schizophrenia Spectrum and Other Psychotic Disorders|Bipolar and Related Disorders|Depressive Disorder|Anxiety Disorders|Personality Disorders|Attention Deficit Hyperactivity Disorder
Interventions: BEHAVIORAL: Winterlight Speech Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Pharmacokinetics and Safety Characteristics of Docetaxel in Patients With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: European Taxotere®|DRUG: American Taxotere®|DRUG: Hospira Docetaxel Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 Immunoglobulin G (rCD4-IgG) in Infants and Children With Documented HIV-1 Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: CD4-IgG
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of the Uterotonic Carbetocin on Acute Post Cesarean-Section Pain
Status: UNKNOWN
Conditions: Cesarean Delivery
Interventions: DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Potentiation of Quetiapine Treatment With Lithium or Aripiprazole in Bipolar 1 Nonresponders Patients
Status: UNKNOWN
Conditions: Bipolar I Disorder
Interventions: DRUG: Lithium|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) Trial of Cardiovascular Events in High-Risk Hypertensive Patients
Status: UNKNOWN
Conditions: Hypertension|Cardiovascular Diseases
Interventions: DRUG: Candesartan cilexetil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Preventing Liver Metastases in Patients With Uveal Melanoma Who HaveMonosomy 3 or DecisionDx Class 2 Disease and Are More Likely to Develop Liver Metastases
Status: TERMINATED
Conditions: Iris Melanoma|Medium/Large Size Posterior Uveal Melanoma|Stage IIA Uveal Melanoma|Stage IIB Uveal Melanoma|Stage IIIA Uveal Melanoma|Stage IIIB Uveal Melanoma|Stage IIIC Uveal Melanoma
Interventions: RADIATION: External Beam Radiation Therapy|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Early Cognitive Stimulation Interventions on Delirium and Cognitive Functions Among Critically Ill Patients
Status: NOT_YET_RECRUITING
Conditions: Delirium
Interventions: OTHER: Early Cognitive Stimulation Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: German Centre for Cardiovascular Research Cardiomyopathy Register
Status: UNKNOWN
Conditions: Acute Myocarditis|Dilated Cardiomyopathies|Hypertrophic Cardiomyopathies|Left Ventricular Myocardial Noncompaction Cardiomyopathy|Arrhythmogenic Right Ventricular Cardiomyopathies|Amyloidosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Imiquimod Versus Conization to Treat Cervical Intraepithelial Neoplasia
Status: TERMINATED
Conditions: Cervical Intraepithelial Neoplasia
Interventions: DRUG: Topical Imiquimod|PROCEDURE: Conization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study in Young Healthy Women to Investigate the Effects of Laquinimod on Standard Oral Contraceptive When Both Treatments Are Given Together
Status: COMPLETED
Conditions: Pharmacokinetics|Pharmacodynamics
Interventions: DRUG: laquinimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Impact of 24/7-phone Support on Readmission After Aortic Valve Replacement, a Randomized Clinical Trial
Status: COMPLETED
Conditions: Aortic Valve Disease
Interventions: OTHER: 24/7-telephone support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six Minute Walking Test Based Index as an Outcome Predictor in COPD Subjects. (Chronic Obstructive Pulmonary Disease)
Status: ACTIVE_NOT_RECRUITING
Conditions: COPD|Mortality|Disease Exacerbation|Exercise Capacity
Interventions: PROCEDURE: evaluation group
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Multicentic Trial in Fertility-sparing Treatment and Ovarian Preservation Management for Early Endometrial Cancer
Status: UNKNOWN
Conditions: Endometrial Cancer
Interventions: PROCEDURE: endometrial cancer radical surgery|PROCEDURE: fertility-sparing surgery|PROCEDURE: ovarian preservation surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Peramivir in Subjects With Uncomplicated Acute Influenza.
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Peramivir 150 mg|DRUG: Peramivir 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Sunitinib With FOLFIRI In Colorectal Cancer
Status: COMPLETED
Conditions: Unresectable or Metastatic Colorectal Cancer
Interventions: DRUG: FOLFIRI (The combination regimen of Irinotecan, l-Leucovorin and 5-Fluorouracil)|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Patch and Bupropion to Reduce Smoking Rates in Younger, Low-Income, and Minority Individuals
Status: COMPLETED
Conditions: Tobacco Use Disorder
Interventions: DRUG: Nicotine Patch|DRUG: Sustained Release Bupropion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prognosis of Isolated Left Ventricular Non-compaction in Adults
Status: COMPLETED
Conditions: Left Ventricular Non Compaction
Interventions: OTHER: Clinical examination|OTHER: Blood sample|PROCEDURE: Echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation
Status: RECRUITING
Conditions: Stem Cell Transplantation|Myelodysplastic Syndromes|Leukemia, Myeloid, Acute|Precursor Cell Lymphoblastic Leukemia-Lymphoma|Lymphoma, Non-Hodgkin
Interventions: BEHAVIORAL: Mindfulness-based Music Therapy (MBMT)|BEHAVIORAL: Mindfulness Meditation (MM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Non-steroidal Anti-inflammatory in Cardiac Surgery
Status: RECRUITING
Conditions: Acute Postoperative Pain|Non-steroidal Anti-inflammatory Drugs|Cardiac Surgery|Pain Intensity|Multimodal Pain Management
Interventions: DRUG: pain management|DRUG: ketoprofen|DRUG: PLacebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Exploring Use of Companion Robot Pets for Older Adults in Care Homes
Status: COMPLETED
Conditions: Aging|Dementia|Neuropsychiatric Symptoms|Wellbeing
Interventions: DEVICE: Two Joy for All robots (one cat and one dog)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Validation of a Remote Wireless Sensor Network (WSN) Approach to the Individualized Detection of Cocaine Use in Humans
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Cocaine hydrochloride|BEHAVIORAL: Exercise|DRUG: Nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicentre Randomised Clinical Trial Comparing Fixed vs Pro re Nata (PRN) Dosing of 700 μg Dexamethasone
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DEVICE: Ozurdex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PURETHAL® Mites Dose Range Finding Study in Patients With Persistent Allergic Rhinitis/Rhinoconjunctivitis
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: PURETHAL Mites 6,667 AU/ml|BIOLOGICAL: PURETHAL Mites 20,000 AU/ml|BIOLOGICAL: PURETHAL Mites 50,000 AU/ml|BIOLOGICAL: PURETHAL Mites 100,000 AU/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LRAMPS Versus LDP in Selected Early-stage Left-sided Pancreatic Cancer
Status: RECRUITING
Conditions: Left-sided Pancreatic Cancer
Interventions: PROCEDURE: LRAMPS|PROCEDURE: LDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Eating Disorders, Self Regulation and Mentalization
Status: COMPLETED
Conditions: Eating Disorders
Interventions: OTHER: Mentalization -based therapy using novel tool to demonstrate eating behavior and control axis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bendamustine and Mitoxantrone in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: bendamustine hydrochloride|DRUG: mitoxantrone hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ventilation Strategies During Spontaneous Breathing Trial
Status: COMPLETED
Conditions: Acute Respiratory Insufficiency
Interventions: PROCEDURE: ATC then pressure support 7 cm H2O PEP 4 cm H2O|PROCEDURE: Pressure support 7 cm H2O PEP 4 cm H2O then ATC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Maintenance Care of Persistent or Recurrent Low Back Pain
Status: COMPLETED
Conditions: Recurrent Low Back Pain|Persistent Low Back Pain|Chronic Low Back Pain
Interventions: OTHER: maintenance care|OTHER: Treatment as needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: Apremilast (CC-10004)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Mental Health Care for Pregnant Women With HIV in Kenya: The Tunawiri Study
Status: NOT_YET_RECRUITING
Conditions: Human Immunodeficiency Virus|Mental Disorder
Interventions: BEHAVIORAL: Collaborative Care Model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: HAIC Combined With Bevacizumab and Toripalimab for Advanced Hepatocellular Carcinama
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Bevacizumab|Liver Neoplasms|Toripalimab|Oxaliplatin
Interventions: PROCEDURE: Hepatic arterial infusion chemotherapy|DRUG: Bevacizumab|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain
Status: COMPLETED
Conditions: Placebo|Expectations
Interventions: BEHAVIORAL: Pain Expectancy Cues|BEHAVIORAL: Vicarious Pain Expectancy Cues|BEHAVIORAL: Cognitive Effort Expectancy Cues
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Erbitux (Cetuximab) in Patients With Metastatic Colorectal Carcinoma
Status: COMPLETED
Conditions: Colorectal Neoplasms|Metastases, Neoplasm
Interventions: BIOLOGICAL: Erbitux (Cetuximab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apnea Positive Pressure Long-Term Efficacy Study
Status: COMPLETED
Conditions: Lung Diseases|Sleep Apnea Syndromes|Sleep
Interventions: DEVICE: Active CPAP|DEVICE: Sham CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing a PTSD m-Health Intervention to Improve Alcohol Treatment Outcomes
Status: RECRUITING
Conditions: Posttraumatic Stress Disorder|Alcohol Use Disorder
Interventions: BEHAVIORAL: PTSD Coach App + Brief Support|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TMC207TBC1003 - A Study in Healthy Volunteers Investigating the Effect of Single-dose TMC207 on the QT/QTc Interval Under Fed Conditions
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Moxifloxacin|DRUG: TMC207|DRUG: TMC207 placebo|DRUG: Moxifloxacin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: BIOLOGICAL: filgrastim|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: etoposide|DRUG: fludarabine phosphate|DRUG: tretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effects of Weight Science and Nutrition Education on Weight Control Beliefs and Disordered Eating.
Status: NOT_YET_RECRUITING
Conditions: Body Image|Eating, Healthy
Interventions: OTHER: Weight Science Educational Video|OTHER: Healthy Eating Educational Video|OTHER: Healthy Sleep Educational Video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Opioid Induced Hyperalgesia (OIH) Modulation With Propranolol
Status: UNKNOWN
Conditions: Hyperalgesia
Interventions: DRUG: Propranolol|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition
Status: UNKNOWN
Conditions: HIV-1-infection|Malnutrition, Child
Interventions: DRUG: Ceftriaxone Sodium|DRUG: Ampicillin|DRUG: Gentamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives.
Status: UNKNOWN
Conditions: Menstrual Migraines|Menstrual Bleeding|Menstrual Spotting
Interventions: DRUG: Estradiol or Placebo|DRUG: Estradiol or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Embrace Scar Therapy Device After Cutaneous Wound Closure
Status: ACTIVE_NOT_RECRUITING
Conditions: Linear Cutaneous Wound
Interventions: DEVICE: Embrace Scar Therapy Device|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients
Status: UNKNOWN
Conditions: Periodontitis Chronic Generalized Severe|Intrabony Periodontal Defect
Interventions: PROCEDURE: Non-Incised Papilla Surgical Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Outcome of BCF Access in Hemodialysis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: End Stage Renal Disease (ESRD)|Brachiocephalic Fistula (BCF)|Cephalic Arch Stenosis (CAS)|Dialysis
Interventions: OTHER: brachiocephalic fistula (BCF)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intracardiac Echocardiography Guided vs. Electroanatomical Mapping System Guided Slow Pathway Ablation in Patients With Atrioventricular Nodal Reentrant Tachycardia
Status: COMPLETED
Conditions: Heart Rhythm Disorder
Interventions: OTHER: Use of intracardiac echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation in Postmenopausal Women With Osteoporosis: Proposal of a Therapeutic Regimen in Practice
Status: UNKNOWN
Conditions: Osteoporosis
Interventions: DRUG: Vitamin D3, 100 000 IU weekly, 4 times|BIOLOGICAL: 25 OH vitamin D serum concentration measurements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CO2 vs. Air Insufflation for Endoscopic Ultrasound
Status: COMPLETED
Conditions: Lesion; Gastrointestinal|Liver, Biliary, Pancreas and Gastrointestinal Disease, Nos
Interventions: OTHER: EUS with air insufflation|OTHER: EUS with CO2 insufflation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capecitabine, Irinotecan, and Oxaliplatin in Treating Patients With Metastatic Cancer
Status: UNKNOWN
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: irinotecan hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Atiprimod Treatment for Patients With Low to Intermediate Grade Neuroendocrine Carcinoma
Status: COMPLETED
Conditions: Neuroendocrine Carcinoma
Interventions: DRUG: Atiprimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Methylprednisolone Plus Ropivacaine Infiltration Before Wound Closure on Laminoplasty or Laminectomy
Status: COMPLETED
Conditions: Postoperative Pain|Neurosurgery
Interventions: DRUG: Methylprednisolone 40 mg + Ropivacaine + Saline|DRUG: Ropivacaine + Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mindfulness-Based Recovery in Veterans
Status: COMPLETED
Conditions: Substance Abuse|Depression|Anxiety Disorder
Interventions: BEHAVIORAL: Mindfulness Based Relapse Prevention (MBRP)|BEHAVIORAL: Twelve-Step Facilitation Intervention (TSF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care
Status: COMPLETED
Conditions: Management of Anticoagulation
Interventions: DEVICE: INRatio monitor by Hemosense|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC