pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate ASP8232 as Add-On Therapy to Angiotensin Converting Enzyme Inhibitor (ACEi) or Angiotensin Receptor Blocker (ARB) in Reducing Albuminuria in Patients With Type 2 Diabetes and Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease|Type 2 Diabetes
Interventions: DRUG: ASP8232|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma|Malignant Metastatic Melanoma
Interventions: BIOLOGICAL: MEDI--522|BIOLOGICAL: Integrin + Dacarbazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Developing an Arts-based Intervention for Patients With End-stage Kidney Disease Whilst Receiving Haemodialysis
Status: COMPLETED
Conditions: Feasibility Study|End Stage Renal Disease on Dialysis (Diagnosis)
Interventions: OTHER: Arts-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC
Status: RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: BAT3306|DRUG: EU-Keytruda®|DRUG: US-Keytruda®|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Brief New Treatment for Suicide Attempts
Status: COMPLETED
Conditions: Suicide, Attempted|Drug Use|Alcohol; Use, Problem
Interventions: BEHAVIORAL: Brief intervention to prevent suicide attempt|BEHAVIORAL: Enhanced treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)
Status: RECRUITING
Conditions: Renal Impairment
Interventions: DRUG: MK-8527
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Octreotide Compared to Placebo in Patients With Inoperable Bowel Obstruction Due to Peritoneal Carcinomatosis
Status: COMPLETED
Conditions: Peritoneal Neoplasms|Intestinal Obstruction|Carcinomatosis
Interventions: DRUG: Octreotide LAR|DRUG: Octreotide (Immediate release)|DRUG: methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of HLX35 in Combination With HLX10 in Patients With Advanced or Metastatic Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor, Adult
Interventions: DRUG: HLX35|DRUG: HLX10
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Music Medicine on Preterm Brain Development and Behavior
Status: NOT_YET_RECRUITING
Conditions: Infant Development|Language Development|Prematurity|Stress
Interventions: OTHER: Music|OTHER: Music and parent voice|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tripegfilgrastim Trial to Reduce the Risk of Severe Neutropenia in Patients With Unresectable Pancreaticobiliary Cancers
Status: NOT_YET_RECRUITING
Conditions: Unresectable Pancreatic Cancer|Unresectable Bile Duct Carcinoma|Unresectable Biliary Tract Carcinoma
Interventions: DRUG: Tripegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Healthy Donor Study II - Comparing Plerixafor With G-CSF and Plerixafor
Status: COMPLETED
Conditions: Malignant Lymphoma, Stem Cell Type
Interventions: DRUG: Plerixafor (Mozobil)|DRUG: Plerixafor + G-CSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy
Status: RECRUITING
Conditions: Ovarian Cancer|Ovarian Carcinoma|Ovarian Cancer Stage IV|Ovarian Cancer Stage III|Ovarian Cancer Stage 3|Endometrial Cancer|Endometrial Cancer Stage
Interventions: OTHER: Exercise|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of tDCS-Induced Neuronal Responses in Multiple Sclerosis (MS) With Advanced MRI
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: tDCS Administration during MRI|DEVICE: Remotely-supervised Daily tDCS Administration|DEVICE: Optional 15 minutes of imaging + simultaneous tDCS up to 4.0mA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Evaluation of Safety and Efficacy of the PrePexTM Device for Rapid Scale up of Adult MC Programs in Zimbabwe
Status: COMPLETED
Conditions: Circumcision Adult|HIV CDC Category B2|HIV Infections
Interventions: DEVICE: PrePex™ device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Exergame in Patients at High Cardiovascular Risk.
Status: COMPLETED
Conditions: Aerobic Exercise|Cardiorespiratory Fitness|Cardiovascular Diseases
Interventions: BEHAVIORAL: exergame|BEHAVIORAL: treadmill exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tacrolimus and Mycophenolate Mofetil in Preventing Acute Graft-Versus-Host Disease in Patients With Advanced Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation
Status: COMPLETED
Conditions: Chronic Myeloproliferative Disorders|Graft Versus Host Disease|Leukemia|Lymphoma|Multiple Myeloma and Plasma Cell Neoplasm|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: mycophenolate mofetil|DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigate the Contribution of Ipatasertib to Neoadjuvant Chemotherapy Plus Atezolizumab in TNBC
Status: ACTIVE_NOT_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Atezolizumab|DRUG: Ipatasertib|DRUG: Paclitaxel|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Stimulation in Neurofibromatosis Type 1
Status: COMPLETED
Conditions: Neurofibromatosis 1
Interventions: OTHER: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects
Status: COMPLETED
Conditions: PD Effects of GS-0976 (NDI-010976) on Fractional DNL
Interventions: DRUG: GS-0976|DRUG: Placebo|OTHER: 1-13C acetate|OTHER: Fructose solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: H01 in Adults With Interstitial Lung Disease (The SOLIS Study)
Status: NOT_YET_RECRUITING
Conditions: Interstitial Lung Disease|Idiopathic Pulmonary Fibrosis|Lung Diseases, Interstitial
Interventions: DRUG: hymecromone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer
Interventions: DRUG: Osimertinib|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to Healthy Adults
Status: COMPLETED
Conditions: Prevention of HIV Infection|HIV Antibodies|Monoclonal Antibody, Human|Neutralizing Antibody
Interventions: BIOLOGICAL: VRC-HIVMAB080-00-AB (VRC01LS)|BIOLOGICAL: VRC-HIVMAB060-00-AB (VRC01)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Vitamin Gum Pharmacokinetics
Status: COMPLETED
Conditions: Nutrient Pharmacokinetics
Interventions: DIETARY_SUPPLEMENT: Vitamingum Sport|DIETARY_SUPPLEMENT: Vitamingum Immunity|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: This is a Prospective, Randomized, Double-Blind Study Comparing Intravesical Injection of Botox® to Placebo.
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DRUG: Botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: CE Mark Study for the Harpoon Medical Device in Poland
Status: COMPLETED
Conditions: Mitral Valve Regurgitation|Mitral Valve Prolapse|Mitral Valve Insufficiency
Interventions: DEVICE: Harpoon Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: sEphB4-HSA in Treating Participants With BCG-Unresponsive or Refractory Bladder Cancer
Status: WITHDRAWN
Conditions: Recurrent Bladder Carcinoma|Bladder Cancer Stage 0|Bladder Cancer Stage I
Interventions: OTHER: Pharmacokinetic Study|BIOLOGICAL: Recombinant EphB4-HSA Fusion Protein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of 11C-MET PET/MRI Imaging in Pediatric Brain Fossa Tumors
Status: COMPLETED
Conditions: Posterior Brain Fossa Tumors in Children
Interventions: PROCEDURE: 11C-MET PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: MILC: A Comprehensive Mobile Application That Addresses the Breastfeeding Challenges of Low-income Hispanic Mothers
Status: NOT_YET_RECRUITING
Conditions: Breastfeeding, Exclusive
Interventions: BEHAVIORAL: MILC application|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's Type
Status: COMPLETED
Conditions: Dementia of Alzheimer's Type
Interventions: DRUG: Donepezil|DRUG: Solifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Multimodal Sexual Dysfunction Intervention In HCT
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation|Hematologic Diseases|Sexual Dysfunction
Interventions: BEHAVIORAL: Enhanced Standard Care|BEHAVIORAL: Multimodal Intervention to Address Sexual Dysfunction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: BPX-01 Minocycline 1% Topical Gel for Reduction of Propionibacterium Acnes
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: BPX-01, 1% Topical Gel|DRUG: BPX-01 Vehicle Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of a Novel Wound Dressing Stratamed Versus Current Clinical Practice After Follicular Unit Extraction Hair Transplantation
Status: COMPLETED
Conditions: Wounds and Injuries
Interventions: DEVICE: Treatment - Stratamed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fatty Acid Radiotracer Comparison Study in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Obesity|Type 2 Diabetes Mellitus|Health Normal Volunteer Subjects
Interventions: DRUG: [18F]FluorbetaOx
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility of n-of-1 Trials - a Pilot Study
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: diclofenac|DRUG: paracetamol|DEVICE: heat retaining knee support|DEVICE: standard knee support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: CLAD Deconvolved PERG Responses in Glaucoma Patients
Status: RECRUITING
Conditions: Glaucoma, Suspect
Interventions: DIAGNOSTIC_TEST: Pattern Electroretinogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial
Status: RECRUITING
Conditions: Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|HER2 Positive Breast Carcinoma|Invasive Breast Carcinoma|Multifocal Breast Carcinoma|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Synchronous Bilateral Breast Carcinoma
Interventions: BIOLOGICAL: Trastuzumab Emtansine|DRUG: Placebo Administration|DRUG: Tucatinib|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Total Intravenous Anesthesia and Volatile Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Laparoscopic or Robotic Assisted Gastrectomy
Status: COMPLETED
Conditions: Gastrostomy
Interventions: DRUG: propofol|DRUG: sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability and Evidence of Activity Study of UBX1325 in Patients With Diabetic Macular Edema (BEHOLD)
Status: COMPLETED
Conditions: Diabetic Macular Edema (DME)
Interventions: DRUG: UBX1325|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin for the Treatment of Pain After Posterior Spinal Fusions
Status: COMPLETED
Conditions: Lumbar Spinal Fusions
Interventions: DRUG: Pregabalin 150 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenvatinib Plus Tislelizumab and CapeOX as First-Line Treatment for Advanced GC/GEJC With Positive PD-L1 and Low TMEscore
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: lenvatinib and tislelizumab plus CapeOX chemotherapy|DRUG: tislelizumab plus CapeOX chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered Dose Inhaler (BDA MDI/PT027) Used 4 Times Daily in Adults and Children 4 Years of Age or Older With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: COMBINATION_PRODUCT: Budesonide/albuterol sulfate metered dose inhaler / BDA MDI 160/180 μg (high dose)|COMBINATION_PRODUCT: Budesonide/albuterol sulfate metered dose inhaler / BDA MDI 80/180 μg (low dose)|DRUG: Budesonide metered dose inhaler / BD MDI 160 µg|DRUG: Albuterol sulfate metered dose inhaler / AS MDI 180 μg|OTHER: Placebo metered-dose inhaler / Placebo MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Small Cell Lung Cancer (SCLC) in Extensive Disease Stage
Status: UNKNOWN
Conditions: Small Cell Lung Cancer
Interventions: DRUG: Carboplatin plus Irinotecan vs Carboplatin plus Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock
Status: COMPLETED
Conditions: Shock,|Sepsis
Interventions: DRUG: Sedation drug (Propofol and Midazolam)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of the Continuous Measurement of Blood Glucose on Insulin Pump on Child Quality of Life With Type 1 Diabetes
Status: COMPLETED
Conditions: Type1diabetes
Interventions: BEHAVIORAL: Peds QL questionnaire and diabetes modulate|BEHAVIORAL: WHO-5 questionnaire|BEHAVIORAL: Felt questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anti-TNFα to Delay or Prevent Progression to Stage 3 T1D
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Golimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Pediatric Procedural Sedation With Rectal Chloral Hydrate or Intranasal Midazolam
Status: WITHDRAWN
Conditions: Traumatic Brain Injury|Computed Tomography|Procedural Sedation
Interventions: DRUG: Midazolam|DRUG: Chloral Hydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vestibular Socket Therapy Using Acellular Dermal Matrix Versus Connective Tissue Graft
Status: ACTIVE_NOT_RECRUITING
Conditions: Immediate Implant
Interventions: DEVICE: implant|PROCEDURE: Vestibular Socket Therapy|DRUG: Alloderm|DRUG: Xenogenic bone membrane shield|PROCEDURE: Connective tissue graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Online Interventions for Gamblers With and Without Co-occurring Mental Health Concerns
Status: COMPLETED
Conditions: Gambling|Depression|Anxiety
Interventions: BEHAVIORAL: Gambling Internet intervention|BEHAVIORAL: MoodGYM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ultrasound-guided Percutaneous Electrolysis in Female Soccer With Soleus Injury
Status: COMPLETED
Conditions: Injury;Sports
Interventions: OTHER: Invasive treatment and exercise therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Citalopram to Enhance Cognition in HD
Status: COMPLETED
Conditions: Huntington Disease|Chorea|Executive Dysfunction
Interventions: DRUG: 20mg daily citalopram|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of OsmoPrep® Tablets Versus HalfLytely® and Bisacodyl Tablet Bowel Prep Kit for Colon Cleansing
Status: COMPLETED
Conditions: Colon Cleansing
Interventions: DRUG: Polyethylene glycol|DRUG: Oral sodium phosphate solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dovitinib Combined With Bortezomib and Dexamethasone for Relapsed/Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Multiple Myeloma
Interventions: DRUG: Dovitinib|DRUG: Bortezomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characterizing the Synergistic Effects of Physical and Cognitive Training on Attention and Working Memory
Status: COMPLETED
Conditions: Healthy Adults
Interventions: BEHAVIORAL: Body-Brain Trainer|BEHAVIORAL: Body Trainer|BEHAVIORAL: Brain Trainer|BEHAVIORAL: Expectancy Matched Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cisplatin, Temozolomide, Abraxane, With Interleukin-2 and Interferon for Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Temozolomide|DRUG: Abraxane|DRUG: Cisplatin|BIOLOGICAL: Interleukin-2|BIOLOGICAL: Interferon alpha 2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion
Status: UNKNOWN
Conditions: Intracranial Embolism|Thrombosis
Interventions: PROCEDURE: transcranial ultrasound in patients treated with iv t-PA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multicenter VESIcare® Efficacy and Safety Study for the Treatment of Urgency Associated With Overactive Bladder (OAB)
Status: COMPLETED
Conditions: Urinary Bladder, Overactive
Interventions: DRUG: VESIcare®|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ethinyl estradiol, norethindrone, VI-0521
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Bucharest Early Intervention Project
Status: ACTIVE_NOT_RECRUITING
Conditions: Cognitive Ability, General|Psychiatric and/or Mood Disorders|Brain Function|Social Cognition|Health Behavior|Risk-Taking|Executive Function
Interventions: OTHER: Foster Care Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Weight Loss Diet and Pumpkin Seed Flour Consumption on Obese Women
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: pumpkin seed flour|DIETARY_SUPPLEMENT: Placebo (cassava flavored flour)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
Status: RECRUITING
Conditions: Clinical Stage 0 Cutaneous Melanoma AJCC v8|Clinical Stage I Cutaneous Melanoma AJCC v8|Clinical Stage IA Cutaneous Melanoma AJCC v8|Clinical Stage IB Cutaneous Melanoma AJCC v8|Clinical Stage II Cutaneous Melanoma AJCC v8|Clinical Stage IIA Cutaneous Melanoma AJCC v8|Clinical Stage IIB Cutaneous Melanoma AJCC v8|Clinical Stage IIC Cutaneous Melanoma AJCC v8|Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8|Colitis|Lung Non-Small Cell Carcinoma|Malignant Genitourinary System Neoplasm|Malignant Solid Neoplasm|Pathologic Stage 0 Cutaneous Melanoma AJCC v8|Pathologic Stage I Cutaneous Melanoma AJCC v8|Pathologic Stage IA Cutaneous Melanoma AJCC v8|Pathologic Stage IB Cutaneous Melanoma AJCC v8|Pathologic Stage II Cutaneous Melanoma AJCC v8|Pathologic Stage IIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIC Cutaneous Melanoma AJCC v8|Pathologic Stage III Cutaneous Melanoma AJCC v8|Pathologic Stage IIIA Cutaneous Melanoma AJCC v8|Pathologic Stage IIIB Cutaneous Melanoma AJCC v8|Pathologic Stage IIIC Cutaneous Melanoma AJCC v8|Pathologic Stage IIID Cutaneous Melanoma AJCC v8|Pathologic Stage IV Cutaneous Melanoma AJCC v8|Stage 0 Lung Cancer AJCC v8|Stage I Lung Cancer AJCC v8|Stage IA1 Lung Cancer AJCC v8|Stage IA2 Lung Cancer AJCC v8|Stage IA3 Lung Cancer AJCC v8|Stage IB Lung Cancer AJCC v8|Stage II Lung Cancer AJCC v8|Stage IIA Lung Cancer AJCC v8|Stage IIB Lung Cancer AJCC v8|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: OTHER: Best Practice|OTHER: Biospecimen Collection|PROCEDURE: Endoscopic Procedure|PROCEDURE: Fecal Microbiota Transplantation|BIOLOGICAL: Infliximab|OTHER: Laboratory Biomarker Analysis|DRUG: Prednisone|BIOLOGICAL: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries
Status: UNKNOWN
Conditions: Pressure Ulcers Stage II|Pressure Ulcers Stage III|Pressure Ulcer, Stage IV
Interventions: DEVICE: Altrazeal® Transforming Powder Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of an Oral, Killed Enterotoxigenic Escherichia Coli Vaccine in Prevention of Diarrhea in Egyptian Infants and Young Children
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: ETEC/rCTB vaccine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ranibizumab in Idiopathic Parafoveal Telangiectasia (RIPT) Trial
Status: COMPLETED
Conditions: Telangiectasia
Interventions: DRUG: Ranibizumab|DRUG: Ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Interventions to Improve Bowel Cancer Screening Uptake in Ireland: a 2x2 Factorial Trial
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Behaviorally enhanced reminder letter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Orthodontic Approaches to Correct Deep Bite in Mixed Dentition Patients
Status: TERMINATED
Conditions: Overbite (Excessive) Deep
Interventions: DEVICE: Fixed appliance|PROCEDURE: Composite bite plane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Mass Balance Study of LCB01-0371 After a Single Oral LCB01-0371 Dose With a [14C]LCB01-0371-microtrace
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LCB01-0371 dose with a [14C]-LCB01-0371-tracer dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing Pain by the painDETECT Questionnaire (PDQ)
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Arthritis|Spondylarthropathies|Rheumatoid Arthritis|Psoriatic Arthritis
Interventions: DRUG: bDMARDS
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)
Status: COMPLETED
Conditions: Platelet Aggregation Inhibitors|Coronary Heart Disease
Interventions: DRUG: Clopidogrel|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trigger Point Injections in Anterior Cervical Surgery
Status: RECRUITING
Conditions: Myofacial Pain|Pain, Neck|Pain, Back|Cervical Fusion
Interventions: DRUG: Trigger point injection with bupivacaine|DRUG: Trigger point injection with normal saline|DRUG: Lidocaine skin wheal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase III Trial of Hyperthermic Isolated Limb Perfusion With Melphalan, Tumor Necrosis Factor, and Interferon-Gamma in Patients With Locally Advanced Extremity Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: melphalan|DRUG: tumor necrosis factor|DRUG: interferon-gamma|PROCEDURE: hyperthermic isolated limb perfusion
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Biomarker-guided Intervention to Prevent Acute Kidney Injury
Status: RECRUITING
Conditions: Acute Kidney Injury
Interventions: OTHER: Comprehensive Implementation of the Bundle recommended by the "Kidney Disease: Improving Global Outcomes Group" (KDIGO bundle)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Two Different Treatments for Lower Pore Renal Stone: Microperc Vs FURS
Status: WITHDRAWN
Conditions: Surgery--Complications|Renal Calculus|Nephrolithiasis|Urolithiasis
Interventions: PROCEDURE: Microperc surgery|PROCEDURE: FURS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TP-0184 to Treat Anemia in Adults With IPSS-R Low or Intermediate Risk MDS
Status: TERMINATED
Conditions: Anemia in Myelodysplastic Syndromes
Interventions: DRUG: TP-0184
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eat, Move, Live Program for the Reduction of Cancer and Chronic Disease Risk in Underserved Communities
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus|Obesity-Related Malignant Neoplasm
Interventions: BEHAVIORAL: Behavioral Intervention|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Online Clinic Pilates Exercises in Patients Undergoing Bariatric Surgery
Status: COMPLETED
Conditions: Bariatric Surgery|Obesity|Exercise|Physical Activity
Interventions: OTHER: Exercise|OTHER: online physical activity counselling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proactive Protection With Azithromycin and hydroxyChloroquine in Hospitalized Patients With COVID-19
Status: TERMINATED
Conditions: Virus Diseases|Infection Viral|Corona Virus Infection
Interventions: DRUG: Azithromycin|DRUG: Hydroxychloroquine|DRUG: Placebo oral tablet|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Ventilation in Reducing the Need for Intubation in Patients With Cancer and Respiratory Failure
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm
Interventions: DRUG: Methylprednisolone|PROCEDURE: Oxygen Therapy|DEVICE: Positive Air Pressure Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantitative Assessment of Distal Radioulnar Joint Stability With Pressure-Monitor Ultrasonography
Status: ENROLLING_BY_INVITATION
Conditions: Distal Radioulnar Joint Sprain|Triangular Fibrocartilage Complex Injury
Interventions: DEVICE: pressure monitor ultrasound system
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Systemic Nickel Allergy Syndrome: Intervention Study for the Assessment of the Dietary Indications
Status: COMPLETED
Conditions: Nickel Sensitivity|Allergy|Nickel; Eczema|Women|Systemic Syndrome
Interventions: OTHER: Dietary protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin E for Prevention of Retinopathy of Prematurity: A Randomized Clinical Trial.
Status: COMPLETED
Conditions: Retinopathy of Prematurity
Interventions: DRUG: Vitamin E|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Local Treatment in ER-positive/HER2-negative Oligo-metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Recurrent Breast Cancer|Stereotactic Body Radiotherapy|Estrogen Receptor Positive Tumor|Her2-negative Tumor|Surgery
Interventions: PROCEDURE: Surgical resection|RADIATION: Stereotactic body radiotherapy|PROCEDURE: Radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Trial of Dexamethasone implAnt for Treatment Naïve diabeTic Macular Edema
Status: UNKNOWN
Conditions: Diabetic Retinopathy
Interventions: DRUG: Dexamethasone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Cohort of STEMI Patients
Status: COMPLETED
Conditions: STEMI - ST Elevation Myocardial Infarction
Interventions: BIOLOGICAL: Blood sampling|PROCEDURE: ECG|DEVICE: MRI|OTHER: Quality of life questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma
Status: RECRUITING
Conditions: Platinum-resistant Ovarian Cancer|Endometrial Adenocarcinoma|Urothelial Carcinoma
Interventions: DRUG: ACR-368|DRUG: Gemcitabine|DIAGNOSTIC_TEST: OncoSignature
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy in Combo With Chemo and Immunotherapy in Patients With PD-L1 Positive Metastatic TNBC
Status: WITHDRAWN
Conditions: Triple Negative Breast Cancer|Locally Advanced Breast Cancer|Unresectable Breast Carcinoma|Metastatic Breast Cancer|PD-L1 Gene Mutation
Interventions: DRUG: Nab-paclitaxel|DRUG: Paclitaxel|RADIATION: Radiation Therapy|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Megachannel Device for Advanced Colonoscopy
Status: COMPLETED
Conditions: Multiple Polyps Right Colon|Large Polyp Right Colon|Suspected Polyp Right Colon
Interventions: DEVICE: Colonoscopy with Megachannel™ device loaded
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients With Blood Disorders
Status: COMPLETED
Conditions: Sickle Cell Anemia|Sickle Cell Disease|Chronic Hemolytic Disorders
Interventions: DRUG: Sodium Nitrite Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Dysfunction After Cataract Surgery
Status: COMPLETED
Conditions: POCD - Postoperative Cognitive Dysfunction
Interventions: DRUG: Ketamine|DRUG: Dexmedetomidine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Semi-sitting Position Versus Supine Position on Gastric Emptying in Children Using Gastric Ultrasound
Status: COMPLETED
Conditions: Anesthesia|Fasting
Interventions: OTHER: Supine position|OTHER: Semi-sitting position
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety, Pharmacokinetic and Pharmacodynamic Effect of KA2237 (PI3 Kinase p110β/δ Inhibitor) In B Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, B Cell
Interventions: DRUG: KA2237
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of the 3rd Booster Dose Using the High or Medium Dose of Inactivated (CoronaVac®) Vaccine in Healthy Adults in Turkey
Status: SUSPENDED
Conditions: COVID-19
Interventions: BIOLOGICAL: Medium-dose COVID-19 Vaccine(Vero Cell),Inactivated|BIOLOGICAL: High-dose COVID-19 Vaccine(Vero Cell),Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Cerebral and Spinal Protection of Xenon Post-conditioning in Patients Undergoing Aortic Dissection Repair
Status: UNKNOWN
Conditions: Aortic Dissection
Interventions: DRUG: xenon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells for Therapy of COVID-19
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: NK cells,IL15-NK cells,NKG2D CAR-NK cells,ACE2 CAR-NK cells,NKG2D-ACE2 CAR-NK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cadonilimab Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC
Status: RECRUITING
Conditions: Cadonilimab|Clear Cell Renal Cell Carcinoma|Neoadjuvant Therapy
Interventions: DRUG: Cadonilimab Combined With Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Candidate Malaria Vaccines in Senegalese Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: ChAd63 ME-TRAP and MVA ME-TRAP|BIOLOGICAL: Rabies vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Aqueous Humor Dynamic Components That Determine Intraocular Pressure Variance
Status: RECRUITING
Conditions: Glaucoma|OHT - Ocular Hypertension
Interventions: DRUG: Timolol 0.5% ophthalmic solution|DRUG: Latanoprost 0.005% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simplified Bowel Preparation Versus Standard Bowel Preparation Before Capsule Endoscopy in Patients With Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: OTHER: capsule endoscopy|OTHER: standard small bowel preparation|OTHER: Simplified small bowel preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Efficacy Study of GSK's Investigational Respiratory Syncytial Virus (RSV) Vaccine in Adults Aged 60 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: RSVPreF3 OA vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Outcomes of NeoMTA and NeoPUTTY Pulpotomies in Primary Molars
Status: NOT_YET_RECRUITING
Conditions: Pulp Disease, Dental
Interventions: OTHER: Primary molars pulpotomies with NeoMTA|OTHER: Primary molar pulpotomies with NeoPUTTY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Individual Pharmacokinetically (PK)-Guided Sunitinib Dosing: A Feasibility Study in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Malignant Solid Tumour
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Premixed Insulins Aspart 30, Aspart 70 and Aspart on Postprandial Lipids
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Insulin Aspart|DRUG: Insulin Aspart 30|DRUG: Insulin Aspart 70
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation
Status: COMPLETED
Conditions: Exercise-induced Asthma
Interventions: OTHER: Exercise challenge in a cold chamber|OTHER: Methacholine challenge|DIETARY_SUPPLEMENT: Oil supplementation verum|DIETARY_SUPPLEMENT: Oil supplementation placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy And Safety Of Illumination Dose Reduction In Red Light Photodynamic Therapy For Actinic Keratoses
Status: NOT_YET_RECRUITING
Conditions: Actinic Keratoses
Interventions: OTHER: Half-dose illumination protocol|OTHER: Full-dose illumination protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HILT or Conventional Combined Physical Therapy, in the Management of Hemiplegic Shoulder Pain
Status: COMPLETED
Conditions: Hemiplegic Shoulder Pain|Hemiplegia|Physical Therapy|High Intensity Laser
Interventions: DEVICE: high intensity laser|DEVICE: tens+us
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Patient Morbidity After Palatal Free Gingival Grafts With or Without PRF Membranes Coverage
Status: COMPLETED
Conditions: Postoperative Pain|Postoperative Complications|Gingival Recession
Interventions: BIOLOGICAL: Platelet rich fibrin ( PRF)|DRUG: hemostatic agents with oxidized and regenerated cellulosa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clomiphene Stair-Step Protocol for Ovulation Induction in Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome
Interventions: DRUG: clomiphene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computerized Working Memory Training in Children With ADHD and Comorbid Tourette Syndrome
Status: COMPLETED
Conditions: Attention-Deficit/Hyperactivity Disorder|Tourette Syndrome
Interventions: BEHAVIORAL: Targeted Cognitive Training (TCT)|OTHER: Youth Appropriate Online Games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Bariatric Surgery on Spermatogenesis
Status: TERMINATED
Conditions: Bariatric Surgery Candidate|Sexual Function and Fertility Disorders
Interventions: DIAGNOSTIC_TEST: Semen Analysis|DIAGNOSTIC_TEST: Hormonal panel|PROCEDURE: RYGB Gastric Bypass|DIAGNOSTIC_TEST: IIEF Survey
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase I Study of Mosunetuzumab for Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia
Status: WITHDRAWN
Conditions: Refractory B-cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Mosunetuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Plus Nerve Stimulator Versus Nerve Stimulator Guided Lumbar Plexus Block
Status: COMPLETED
Conditions: Knee Arthroscopy Surgery
Interventions: PROCEDURE: Ultrasound and nerve stimulator guided lumbar plexus block|PROCEDURE: Nerve stimulator guided lumbar plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rood's Approach and Oxaliplatin-induced Peripheral Neuropathy in Colorectal Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Peripheral Neuropathy
Interventions: OTHER: Rood's approach|OTHER: Traditional physical therapy program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT