pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Asymptomatic Cardiac Ischemia Pilot (ACIP) Study
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: atenolol|DRUG: nifedipine|DRUG: diltiazem|DRUG: isosorbide dinitrate|PROCEDURE: coronary artery bypass coronary artery bypass|PROCEDURE: angioplasty, transluminal, percutaneous coronary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neuromuscular Electrical Stimulation For The Treatment of Diabetic Neuropathy
Status: RECRUITING
Conditions: Diabetic Peripheral Neuropathy|Diabetic Neuropathies|Diabetic Polyneuropathy|Diabetic Complication
Interventions: DEVICE: Revitive Medic Coach (Actegy Ltd)|DEVICE: Sham Revitive Medic Coach (Actegy Ltd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Preconditioning in Coronary Artery Bypass Grafting With Cold Crystalloid Cardioplegic Arrest
Status: COMPLETED
Conditions: Myocardial Injury
Interventions: PROCEDURE: RIPC|PROCEDURE: Control|DRUG: isoflurane+sufentanil anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: VX-702
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Neoadjuvant Immunochemotherapy in Elderly Patients With Resectable Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Carboplatin|DRUG: Nab paclitaxel|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Multicenter Study of Daylight Mediated Photodynamic Therapy (PDT)
Status: COMPLETED
Conditions: Actinic Keratoses
Interventions: PROCEDURE: Photodynamic therapy with methyl aminolevulinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Healthy and Renal Impairment Study of Colcrys (Colchicine, USP)
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Effect of Theipoental and Propofol in IVF Outcome
Status: COMPLETED
Conditions: Subfertility
Interventions: DRUG: Propofol|DRUG: Thiopental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Homologous Booster Study of COVID-19 Protein Subunit Recombinant Vaccine
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-CoV-2 Subunit Recombinant Protein Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy
Status: COMPLETED
Conditions: Hypercholesterolaemia
Interventions: DRUG: Alirocumab SAR236553|DEVICE: Current auto-injector device (AI)|DEVICE: New auto-injector device (SYDNEY)|DRUG: Atorvastatin|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Subclavian Vein Catheterisation With a Needle Guide
Status: RECRUITING
Conditions: Complications; Catheter, Mechanical|Catheterization, Central Venous
Interventions: DEVICE: Needle guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: aleglitazar|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effects of Gabapentin Premedication on Neurosurgery
Status: COMPLETED
Conditions: Cerebral Tumor
Interventions: DRUG: gabapentin|DRUG: vitamin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery
Status: COMPLETED
Conditions: To Control Pain After Third Molar Surgery
Interventions: DRUG: Paracetamol Codeine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factor Xa Inhibitor YM150 for the Prevention of Blood Clot Formation in Veins After Scheduled Hip Replacement (ONYX-2)
Status: COMPLETED
Conditions: Thromboembolism
Interventions: DRUG: YM150
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Rocker Board and Stable Surface Training on Postural Stability, Balance and Gait
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: Rocker board training|OTHER: Stable surface training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Intubating Laryngeal Mask FASTRACH™ and the Intubating Laryngeal Mask Ambu Aura-i™
Status: COMPLETED
Conditions: Airway Management|Laryngeal Mask Airway|Fibreoptic Intubation
Interventions: DEVICE: Crossover Ambu Aura-i™ / Rüsch Super Safety Silk™|DEVICE: Crossover Ambu Aura-i™ / LMA ETT™|DEVICE: Crossover FASTRACH™ / Rüsch Super Safety Silk™|DEVICE: Crossover FASTRACH™ / LMA ETT™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Types of Resistant Starch and Their Effect on Appetite
Status: COMPLETED
Conditions: Psychological Phenomena and Processes
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Starch composite B|DIETARY_SUPPLEMENT: Starch composite C|DIETARY_SUPPLEMENT: Starch composite D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Arthroscopic Labral Repair Versus Physical Therapy for Tears of the Acetabular Labrum
Status: ACTIVE_NOT_RECRUITING
Conditions: Acetabular Labrum Tear|Femoro Acetabular Impingement|Hip Arthroscopy|Physical Therapy|Osteoarthritis, Hip
Interventions: PROCEDURE: Hip Arthroscopy Surgery with Acetabular Labral Repair (SPT group)|PROCEDURE: Physical Therapy Focused on the Hip and Hemi-pelvis (PT group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chronic Non-bacterial Osteomyelitis Treated With Pamidronate
Status: UNKNOWN
Conditions: Immune System Disease|Musculoskeletal Disease
Interventions: DRUG: Pamidronatdinatrium|OTHER: Natrium chloride 9mg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Cardiovascular Risk Factors by the Diet
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Cardioprotective diet|DIETARY_SUPPLEMENT: Cardioprotective diet + 3 g EPA + DHA/d
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Look at How GSK1325756 is Taken up by the Body When Given by Mouth When Stomach Acid is Reduced
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK1325756
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Multicenter, Open Label, Prospective, Non-randomized Study of the InCraft® Stent Graft System in Subjects With Abdominal Aortic Aneurysms (INSPIRATION)
Status: COMPLETED
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: Endovascular AAA repair with InCraft®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety And Efficacy Results of Percutaneous Renal Stent Implantation in Ectatic and Aneurysmatic Coronary Arteries
Status: COMPLETED
Conditions: Coronary Artery Ectasia
Interventions: DRUG: Renal stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research for Two Medical Home Models for Attention Deficit Hyperactivity Disorder
Status: COMPLETED
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: BEHAVIORAL: Collaborative Care Plus|BEHAVIORAL: Traditional Collaborative Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: OrthoPulse Gen 2 Initial Device Evaluation and Assessment of Clinical Effectiveness (CA)
Status: TERMINATED
Conditions: Orthodontic Tooth Movement
Interventions: DEVICE: Intervention 1|DEVICE: Intervention 2|DEVICE: Intervention 3|DEVICE: Intervention 4|DEVICE: Intervention 5|DEVICE: Intervention 6|DEVICE: Intervention 7|DEVICE: Intervention 8
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Comparing Stereotactic Body Radiation Therapy to Radiofrequency Ablation for Renal Cell Carcinoma
Status: TERMINATED
Conditions: Renal Cell Carcinoma
Interventions: RADIATION: SBRT|RADIATION: RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doppler Findings in the Fetal Cerebral Blood Vessels (VA/MCA) Within 24 Hours Before Delivery and Relation With Perinatal Outcome.
Status: RECRUITING
Conditions: Ultrasonography, Doppler|Obstetric Labor Complications
Interventions: OTHER: Ultrasound examination in early labor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Study Evaluating Efficacy and Safety of 177Lu-DOTA-TATE Based on Kidney-Dosimetry in Patients With Disseminated Neuroendocrine Tumors
Status: COMPLETED
Conditions: Neuroendocrine Tumors|Liver Metastases
Interventions: DRUG: 177Lu-DOTA-TATE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preoperative Nerve Block for Rhinoplasty/Septoplasty
Status: UNKNOWN
Conditions: Nasal Fracture|Deviated Nasal Septum
Interventions: DRUG: Nerve block|DRUG: Placebo Saline Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Sanofi H1N1 + TIV - Adults and Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Trivalent inactivated influenza vaccine|BIOLOGICAL: Inactivated H1N1 Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sequential Infusion of Anti-CD19 and Anti-CD20 CAR-T Cells Against Relapsed and Refractory B-cell Lymphoma
Status: UNKNOWN
Conditions: Recurrent or Refractory B Cell Malignancy
Interventions: BIOLOGICAL: Mixed CD19/CD20 CAR-T Transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nut Allergy Study: Double-blind Challenge and Oral Desensitization
Status: COMPLETED
Conditions: Nut Allergy
Interventions: DIETARY_SUPPLEMENT: Nut challenge|DIETARY_SUPPLEMENT: Nut challenge: Placebo|DIETARY_SUPPLEMENT: Nut oral desensitization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Uncut Roux-en-y Anastomosis Reduce Postoperative Complication and Improve Nutritional Status After Distal Gastrectomy
Status: UNKNOWN
Conditions: Nutrition Disorders|Postoperative Complications
Interventions: PROCEDURE: Uncut Roux-en-Y anastomosis|PROCEDURE: Billroth II anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Pressure Support Reduction Versus Spontaneous Breathing Trials in Weaning From Ventilation
Status: UNKNOWN
Conditions: Respiration, Artificial|Ventilator Weaning
Interventions: PROCEDURE: Pressure support ventilation|PROCEDURE: Spontaneous breathing trials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications
Status: TERMINATED
Conditions: Non-squamous Non-small Cell Lung Cancer|Epithelial Ovarian Cancer|Claudin 6-positive Advanced/Metastatic Malignant Solid Tumors
Interventions: DRUG: AMG 794
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)
Status: COMPLETED
Conditions: Myelodysplastic Syndrome|MDS
Interventions: DRUG: ASTX727 Dose Escalation|DRUG: ASTX727 Dose Confirmation|DRUG: ASTX727 Fixed-Dose Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-BARICARE to Manage COVID-19-Related Distress
Status: RECRUITING
Conditions: Obesity|Bariatric Surgery Candidate|Mental Health Disorder|Eating Disorders
Interventions: BEHAVIORAL: Tele-CBT|OTHER: Self-Help Resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: REperfusion With P2Y12 Inhibitors in Addition to mEchanical thRombectomy for perFUsion Imaging Selected Acute Stroke patiEnts
Status: RECRUITING
Conditions: Acute Ischemia
Interventions: DRUG: Cangrelor|OTHER: best medical management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability and Activity of Different Formulations of Insulin Glargine and Lixisenatide in Patients With Diabetes Mellitus Type 1
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Insulin glargine HOE901|DRUG: Lixisenatide AVE0010
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Human CMV pp65-LAMP mRNA-pulsed autologous DCs|DRUG: Temozolomide|BIOLOGICAL: Varlilumab|BIOLOGICAL: Td|BIOLOGICAL: Unpulsed DCs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Fish Oil in Lupus Patients
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Omega-3|DEVICE: flow-mediated dilation of the brachial artery|OTHER: corn starch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Concentrations of Xylitol and Erythritol on Gut Peptide Release and Gastric Emptying in Humans
Status: COMPLETED
Conditions: Physiological Satiation Mechanisms
Interventions: DIETARY_SUPPLEMENT: Xylitol 7g|DIETARY_SUPPLEMENT: Erythritol 10g|DIETARY_SUPPLEMENT: Xylitol 17g|DIETARY_SUPPLEMENT: Xylitol 35g|DIETARY_SUPPLEMENT: Erythritol 25g|DIETARY_SUPPLEMENT: Erythritol 50g
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud's Phenomenon
Status: COMPLETED
Conditions: Raynaud Phenomenon
Interventions: DIETARY_SUPPLEMENT: Concentrated beetroot juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation
Status: ENROLLING_BY_INVITATION
Conditions: Interstitial Fibrosis|Kidney Transplant; Complications|Kidney Transplant Rejection|Kidney Transplant Failure and Rejection|Kidney Transplant Failure|Kidney Failure, Chronic|Graft Rejection
Interventions: DRUG: Fingolimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of Phytosterols on Nonalcoholic Fatty Liver Disease
Status: COMPLETED
Conditions: Non-alcoholic Fatty Liver Disease
Interventions: DIETARY_SUPPLEMENT: Phytosterols & placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: T-DXd Versus THP for Medium-risk HER2-positive Early Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HER2-positive Breast Cancer
Interventions: DRUG: T-DXd|DRUG: THP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Effectiveness of BGB-A445 in Combination With Tislelizumab in Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumor|Non Small Cell Lung Cancer|Head and Neck Squamous Cell Carcinoma (HNSCC)|Nasopharyngeal Carcinoma (NPC)
Interventions: DRUG: BGB-A445|DRUG: tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sternalock Versus Wires for Sternal Closure Study
Status: COMPLETED
Conditions: Cardiac Surgery|Sternal Closure
Interventions: DEVICE: Sternalock 360 sternal plating system|DEVICE: Sternal Wires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study(Additional) of URC102 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: URC102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effects of Repeated Doses of 3BNC117-LS and 10-1074-LS on Persistent Viral Reservoirs in People Living With HIV and on Suppressive Antiretroviral Therapy
Status: RECRUITING
Conditions: HIV-1
Interventions: BIOLOGICAL: 3BNC117-LS|BIOLOGICAL: 10-1074-LS|OTHER: Sterile Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: tirapazamine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: REEV SENSE for Gait Analysis in Post-stroke Gait Impairment (SENS-AG)
Status: RECRUITING
Conditions: Stroke|Gait Disorders, Neurologic
Interventions: DEVICE: REEV SENSE|DEVICE: Motion capture system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Man Clinical Trial of Emodepside (BAY 44-4400)
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: emodepside (BAY 44-4400)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Central Mechanism of Acupuncture for Treating Chronic Subjective Tinnitus Assessed by fNIRS
Status: NOT_YET_RECRUITING
Conditions: Tinnitus
Interventions: PROCEDURE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics/Pharmacodynamics of Argatroban Injection in End-Stage Renal Disease Patients Undergoing Hemodialysis
Status: COMPLETED
Conditions: Kidney Failure, Chronic|Renal Disease, End-Stage
Interventions: DRUG: Argatroban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kg
Status: COMPLETED
Conditions: Acute Uncomplicated Falciparum Malaria
Interventions: DRUG: Artemether-lumefantrine (COA566)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH
Status: TERMINATED
Conditions: PAH|Pulmonary Hypertension|Hypertension|Connective Tissue Disease|Familial Primary Pulmonary Hypertension|Vascular Diseases|Cardiovascular Diseases|Hypertension, Pulmonary|Lung Diseases|Respiratory Tract Disease|Pulmonary Arterial Hypertension
Interventions: DRUG: Ralinepag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerance of Stavudine (d4T) in Combination With Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants
Status: COMPLETED
Conditions: HIV Infections|Pregnancy
Interventions: DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Success Rate of the Miniscrews in the Mandibular Buccal Shelf
Status: COMPLETED
Conditions: Class III Malocclusion
Interventions: PROCEDURE: Orthodontic miniscrew insertion in the mandibular buccal shelf
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Loxapine Succinate Capsules 25 mg and Loxitane® Capsules 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Loxapine Succinate Capsules 25 mg|DRUG: Loxitane® Capsules 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Effect of Two Online Interventions -Watch Your Weight During the Holidays Program and the Relative 5:2 Fasting- for the Prevention of Body Weight Gain at 8 Weeks in Mexican Adults in the Covid-19 Pandemic
Status: TERMINATED
Conditions: Weight Gain|Overweight|Obesity
Interventions: BEHAVIORAL: Watch your Weight During the Holidays Program|OTHER: Relative 5:2 Fasting|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin
Status: COMPLETED
Conditions: Vertigo, Peripheral
Interventions: DRUG: Meclizine|DRUG: Dimenhydrinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Evaluation of Nasolabial Changes Following Classic Versus Modified Alar Base Suture After Le Fort I Osteotomy
Status: UNKNOWN
Conditions: Le Fort; I
Interventions: PROCEDURE: Classic alar base suture technique|PROCEDURE: Modified alar base suture technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Sertraline to Prevent PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: DRUG: Placebo|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Investigation Into The Anti-hypertensive And Potential Anti-inflammatory Actions Of Dapagliflozin
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: dapagliflozin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microvascular and Antiinflammatory Effects of Rivaroxaban Compared to Aspirin in Type-2 Diabetic Patients With Subclinical Inflammation and High Cardiovascular Risk
Status: COMPLETED
Conditions: Type 2 Diabetic Patients
Interventions: DRUG: Rivaroxaban|DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fixed Low-dose Eltrombopag and rhTPO for Immune Thrombocytopenia (FLOWER)
Status: UNKNOWN
Conditions: Immune Thrombocytopenia
Interventions: DRUG: Eltrombopag|DRUG: rhTPO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCL
Status: NOT_YET_RECRUITING
Conditions: Diffuse Large B Cell Lymphoma
Interventions: DRUG: Polatuzumab vedotin|DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|DRUG: Orelabrutinib|DRUG: Venetoclax|DRUG: Chidamide|DRUG: Penpulimab|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cemented vs Non-cemented Semiendoprosthesis in the Treatment of Proximal Femoral Fractures
Status: UNKNOWN
Conditions: Hip Fracture|Proximal Femoral Fracture
Interventions: DEVICE: Cemented semiendoprosthesis|DEVICE: non-cemented
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Trial of MLN8237 in Patients With Metastatic Castrate Resistant and Neuroendocrine Prostate Cancer
Status: COMPLETED
Conditions: Small Cell Prostate Cancer|Neuroendocrine Prostate Cancer|Prostate Adenocarcinoma Plus > 50% Immunohistochemical Staining for Neuroendocrine Markers
Interventions: DRUG: MLN8237
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental Erosion
Status: UNKNOWN
Conditions: Tooth Erosion|Teeth Erosion Due to Vomiting|Teeth Erosion Limited to the Enamel|Teeth Erosion Extending Into the Dentine
Interventions: PROCEDURE: Ceramic ultrathin occlusal veneers|PROCEDURE: Composite resin ultrathin occlusal veneers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
Status: RECRUITING
Conditions: Cardiovascular Diseases
Interventions: OTHER: Healthy Dietary Pattern with Cottonseed Oil|OTHER: Healthy Dietary Pattern with Fatty Acid-Matched Plant Oils|OTHER: Healthy Dietary Pattern with PUFA:SFA Ratio-Matched Plant Oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults
Status: RECRUITING
Conditions: Alcohol Abuse
Interventions: BEHAVIORAL: Brief Alcohol Intervention (BAI)|BEHAVIORAL: Substance-free Activity Session (SFAS)|BEHAVIORAL: Relaxation Training (RT)|OTHER: Education Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure Treatment in ICU Patients With Subarachniodal Haemorrhage.
Status: RECRUITING
Conditions: Blood Pressure|Subarachnoid Hemorrhage|Aneurysm Cerebral
Interventions: OTHER: Blood pressure elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 5E Program for Preventing Venous Thromboembolism in Patients With Spinal Cord Disorders
Status: RECRUITING
Conditions: Venous Thromboembolism|Spinal Cord Diseases|Spinal Cord Injuries|Nurse's Role
Interventions: BEHAVIORAL: 5E program
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Use of Lipid Emulsion or Nanoemulsion of Propofol on Children Undergoing Ambulatory Invasive Procedures.
Status: WITHDRAWN
Conditions: Leukemia
Interventions: DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Apathy in Tourette Syndrome and Changes in Quality of Life
Status: COMPLETED
Conditions: Tourette Syndrome|Apathy
Interventions: OTHER: Children's Motivation Scale|OTHER: Yale Global Tic Severity Scale (YGTSS)|OTHER: Studies Depression Scale for Children (CES-DC)|OTHER: Gilles de la Tourette Syndrome Quality Of Life scale|OTHER: Demographic Data
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: tDCS Intervention on Motivational Anhedonia of Major Depressive Disorder
Status: UNKNOWN
Conditions: Transcranial Direct Current Stimulation|Major Depressive Disorder|Event-Related Potentials
Interventions: DEVICE: transcranial direct current stimulation with real current|DEVICE: transcranial direct current stimulation with sham current
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of New Enhanced Ostomy Device in Real-life Settings in Subjects Having a Stoma
Status: COMPLETED
Conditions: Ileostomy - Stoma|Colostomy Stoma
Interventions: DEVICE: Test Product A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optune® Plus Bevacizumab in Bevacizumab-Refractory Recurrent Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma|Glioma|Gliosarcoma
Interventions: DRUG: Bevacizumab|DEVICE: TTFields Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemoradiotherapy in Esophageal or Esophagogastric Junction Cancer
Status: RECRUITING
Conditions: Esophagus Cancer|Esophagogastric Junction Cancer|Chemoradiation|Targeted Therapy|Immunotherapy|Chemotherapy Effect
Interventions: RADIATION: Radiotherapy|DRUG: Platinum based chemotherapy|DRUG: Paclitaxel based chemotherapy|DRUG: Immunotherapy|DRUG: 5-FU Analog based chemotherapy|DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dopamine Responsivity in Gamblers
Status: COMPLETED
Conditions: Pathological Gambling
Interventions: DRUG: Tolcapone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Novel Influenza A/H1N1 Split- Virion Vaccine in Healthy Children Aged 6 to 35 Month
Status: UNKNOWN
Conditions: Influenza|Swine-origin A/H1N1 Influenza
Interventions: BIOLOGICAL: 7.5ug H1N1 Influenza vaccine|BIOLOGICAL: 15ug H1N1 vaccine|BIOLOGICAL: seasonal influenza vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI)
Status: UNKNOWN
Conditions: Myocardial Infarction|Hypothyroidism
Interventions: DRUG: Levothyroxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Artificial Intelligence (AI) Assisted Real-time Adenoma Detection During Colonoscopies
Status: RECRUITING
Conditions: Artificial Intelligence
Interventions: DEVICE: Medtronic-GI genius (CADe system for detecting colorectal polyps)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Co'Moon for Supporting Breast Cancer Patients on Adjuvant Endocrine Therapy
Status: COMPLETED
Conditions: Breast Cancer|Quality of Life|Self Efficacy
Interventions: DEVICE: Co'moon (online website to support women with AET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Capecitabine With or Without Sunitinib Malate as First-Line Therapy in Treating Patients With Metastatic Cancer of the Esophagus or Gastroesophageal Junction
Status: COMPLETED
Conditions: Adenocarcinoma of the Gastroesophageal Junction|Esophageal Cancer
Interventions: DRUG: capecitabine|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Self-Recognition and Self/Other Distinction Disorders in Patients With Psychological Vulnerability
Status: RECRUITING
Conditions: Psychosis of Childhood Borderline|Psychotic Disorder
Interventions: OTHER: Double mirror device ALTER-EGO|OTHER: EASE test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clot Formation and Clot Stability in Patients With Severe Haemophilia A
Status: COMPLETED
Conditions: Hemophilia A
Interventions: DRUG: ReFacto (Recombinant factor VIII) and Tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RTX-224 Monotherapy in Patients With Solid Tumors
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Cutaneous Melanoma|Head and Neck Squamous Cell Carcinoma|Urothelial Carcinoma|TNBC - Triple-Negative Breast Cancer
Interventions: DRUG: RTX-224
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: OTL38|DEVICE: intraoperative imaging camera system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Combined AlloStim+Anti-PD-L1 in MSS Metastatic Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: BIOLOGICAL: AlloStim|DRUG: Bavencio
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D-printed Module-assisted Minimally Invasive Lumbar Pedicle Screw Placement
Status: COMPLETED
Conditions: Thoracolumbar; Spina Bifida
Interventions: PROCEDURE: 3D printed module
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: insulin lispro protamine suspension:insulin lispro rDNA origin low mix|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness|Sepsis|Multiple Organ Failure
Interventions: OTHER: Glutamine|OTHER: Antioxidants|OTHER: Glutamine + Antioxidants|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Intensity Strength Training and Muscle Energy Techniques in TKR Patients
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis|Arthroplasty, Knee Replacement|Resistance Training
Interventions: OTHER: High Intensity Strength Training|OTHER: Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Warning and Intervention Mechanism of Foot Health Risk in Children and Adolescents
Status: RECRUITING
Conditions: Flexible Flatfoot
Interventions: PROCEDURE: Whole-Body Vibration Intervention|PROCEDURE: Exercise Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test How Well Different Doses of BI 764532 in Combination With Ezabenlimab Are Tolerated by People With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3
Status: RECRUITING
Conditions: Small Cell Lung Carcinoma (SCLC)|Neuroendocrine Neoplasms
Interventions: DRUG: BI 764532|DRUG: Ezabenlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Motivational Techniques to Increase Levels of Physical Activity in Long Term Psychiatric Inpatient Wards
Status: COMPLETED
Conditions: Schizophrenia|Bipolar Disorder|Inpatient Facility Diagnoses|Cardiovascular Risk Factor
Interventions: BEHAVIORAL: Motivational interviewing and environmental interventions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State
Status: UNKNOWN
Conditions: Traumatic Brain Injury
Interventions: PROCEDURE: Sensory Stimulation|DEVICE: Sesnory Modality Assessment and Rehabilitation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome
Status: NOT_YET_RECRUITING
Conditions: Polycystic Ovary
Interventions: DRUG: Metformin|DRUG: Dapagliflozin|DRUG: Dapagliflozin/Metformin|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy|Chronic Stable Illness
Interventions: DRUG: casirivimab+imdevimab|BIOLOGICAL: Moderna mRNA-1273 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-adherent Absorbent Silver Dressing in Adults After Hip or Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasties, Hip Replacement|Arthroplasties, Knee Replacement
Interventions: DEVICE: Mepilex Border Post-Op Ag
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Efficacy of the VytronUS Low-Intensity Collimated Ultrasound Ablation System
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation
Interventions: DEVICE: VytronUS Ablation System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional Bevacizumab Injection on Primary Pterygium
Status: UNKNOWN
Conditions: Pterygium|Inflammation
Interventions: DRUG: Intralesional injection of bevacizumab|DRUG: Topical antihistamine and vasoconstrictor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sofosbuvir With Pegylated Interferon and Ribavirin Hepatitis C Virus (HCV) Genotypes 1,4,5,6
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: DRUG: Sofosbuvir|DRUG: RBV|DRUG: PEG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Results and RSA Migration Analysis of the GLOBAL ICON - Stemless Anatomic Shoulder
Status: RECRUITING
Conditions: Osteoarthritis of the Shoulder
Interventions: DEVICE: Total joint arthroplasty of the glenohumeral joint
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genetic Architecture of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: RECRUITING
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Interventions: GENETIC: Genome-wide association study
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Triadic Interactions of Families With Autism and Oxytocin
Status: WITHDRAWN
Conditions: Autism Disorder
Interventions: DRUG: Oxytocin|DRUG: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Group Interpersonal Psychotherapy in Treating Women With Prenatal Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Group interpersonal therapy (IPT)|BEHAVIORAL: Treatment as usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hemodynamic and Electrocardiographic Effects of Hyaluronidase Associated With Local Anaesthetics
Status: COMPLETED
Conditions: Cardiac Arrhythmias
Interventions: DRUG: 3.6mL 2% Mepivacaine with 1:100,000 epinephrine|PROCEDURE: Lower Third Molar Extraction|DRUG: Hyaluronidase|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study of Ceftobiprole to Evaluate Pharmacokinetics in Adults Hospitalized in the ICU
Status: COMPLETED
Conditions: ICU
Interventions: DRUG: ceftobiprole q12h|DRUG: ceftobiprole q8h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of 1:1 Inspiratory to Expiratory Ratios on Oxygenation and Intrapulmonary Shunt Fraction During One Lung Ventilation in the Obese Patients
Status: COMPLETED
Conditions: Obese Patients, One Lung Ventilation
Interventions: PROCEDURE: I:E ratio 1:2|PROCEDURE: I:E ratio 1:1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Carmustine and O(6)-Benzylguanine in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
Status: WITHDRAWN
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: O6-benzylguanine|DRUG: carmustine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases
Status: COMPLETED
Conditions: Liver Neoplasms|Colonic Neoplasms|Metastatic Cancer to Liver
Interventions: RADIATION: Stereotactic Radiosurgery using the CyberKnife System.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Human Cytomegalovirus (HCMV) Vaccine SPYVLP01 With and Without Adjuvants
Status: RECRUITING
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: SPYVAC01
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION