pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Parent-Child Single-Session Growth Mindset Intervention on Adolescent Depression and Anxiety Problems
Status: NOT_YET_RECRUITING
Conditions: Depression, Anxiety
Interventions: BEHAVIORAL: The Parent-Child Single-Session-intervention of Mindset Intelligence, Failure and Emotion (PC-SMILE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of Oral ASN51 in Healthy Subjects and Subjects With Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer Disease
Interventions: DRUG: ASN51|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interferon Alfa in Treating Patients With Recurrent Unresectable Meningiomas and Malignant Meningiomas
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: Recombinant Interferon Alfa (INF alpha)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Look at Benefit of Surgical Drainage Before Beginning Medical Therapy for Crohns Perianal Fistulas
Status: COMPLETED
Conditions: Crohns Disease|Fistula|Abscess
Interventions: PROCEDURE: Exam under anesthesia (EUA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Marcaine Use in Laparoscopic Gynecological Surgery
Status: TERMINATED
Conditions: Post-operative Pain
Interventions: DRUG: Marcaine- 0.25%|DRUG: Marcaine 0.25%.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Can Beta-Hydroxy-beta-Methylbutyrate Supplementation Counteract Muscle Catabolism in Critically Ill Patients?
Status: COMPLETED
Conditions: Critical Illness|Muscle Weakness
Interventions: DIETARY_SUPPLEMENT: HMB (beta-hydroxy beta-methylbutyrate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.
Status: COMPLETED
Conditions: Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia
Interventions: DRUG: nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tacrolimus Combined With Low-dose Prednisone for Treatment of Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: Pyridostigmine, Prednisone, Tacrolimus|DRUG: Pyridostigmine, Tacrolimus
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus
Interventions: DRUG: BGP-15 100 mg QD|DRUG: BGP-15 100 mg BID|DRUG: Placebo BID|DRUG: BGP-15 200 mg QD|DRUG: BGP-15 200 mg BID|DRUG: BGP-15 400 mg QD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Rehydration Solution and Dehydration Recovery
Status: RECRUITING
Conditions: Dehydration
Interventions: OTHER: Oral Rehydration Solution (ORS)|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Investigation of the Potential Pharmacokinetic Interaction Between Nevirapine, Abacavir and Amprenavir in HIV-1 Infected Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Naive Adults
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Nevirapine|DRUG: Amprenavir|DRUG: Abacavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maternal Immunization With MenAfriVac™
Status: UNKNOWN
Conditions: Meningitis|Meningococcal
Interventions: BIOLOGICAL: meningococcal serogroup A conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pure Florid and Pleomorphic Lobular Carcinoma in Situ of the Breast: Towards an Increasingly Uniform Management
Status: RECRUITING
Conditions: Pleomorphic Lobular Breast Carcinoma in Situ|Breast Florid Lobular Carcinoma in Situ
Interventions: PROCEDURE: Surgical wide local excision|PROCEDURE: Cavity shaving|PROCEDURE: Excision margin surgical clearance|RADIATION: Adjuvant Radiotherapy|BIOLOGICAL: Adjuvant Hormone Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of the Safety and Efficacy of THL-P in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DIETARY_SUPPLEMENT: THL-P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy and Tolerance of Sub-cutaneous Re-injection of Autologous Adipose-derived REGEnerative Cells in the Local Treatment of Neuropathic Diabetic Foot ulcERs
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: adipose-derived regenerative cells (ADRCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Gene-knocked Out Mesothelin-directed CAR-T Cells With the Conditioning of PC in Mesothelin Positive Multiple Solid Tumors
Status: UNKNOWN
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: Mesothelin-directed CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study
Status: COMPLETED
Conditions: Degenerative Disc Disease
Interventions: DEVICE: rhBMP-2/CRM/CD HORIZON® Spinal System|DEVICE: Autograft/CD HORIZON® Spinal System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-escalating Trial With UniCAR02-T Cells and CD123 Target Module (TM123) in Patients With Hematologic and Lymphatic Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DRUG: Cyclophosphamide (Non-IMP)|DRUG: Fludarabine (Non-IMP)|DRUG: TM123 (IMP)|DRUG: UniCAR02-T (IMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of rhuMAb Beta7 in Patients With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: placebo|DRUG: rhuMAb Beta7
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MEDI7183 Phase 2 Study in Japanese Ulcerative Colitis Patients
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: MEDI7183 low dose|DRUG: MEDI7183 medium dose|DRUG: MEDI7183 high dose|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance
Status: COMPLETED
Conditions: Type 1 Diabetes|Type 2 Diabetes
Interventions: DEVICE: Bionic Pancreas|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Strategies for Anticoagulation During Venovenous ECMO
Status: RECRUITING
Conditions: Acute Hypoxemic Respiratory Failure|Anticoagulant-induced Bleeding|Thromboembolism
Interventions: OTHER: Low intensity anticoagulation|OTHER: Moderate Intensity Anticoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of USL311 +/- Lomustine in Advanced Solid Tumors or Relapsed/Recurrent Glioblastoma Multiforme (GBM)
Status: TERMINATED
Conditions: Solid Tumors (Phase 1)|Relapsed/Recurrent GBM (Phase 2)
Interventions: DRUG: USL311|DRUG: USL311|DRUG: USL311|DRUG: Lomustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Two Medtronic Infusion Sets on Lipohypertrophy in Type 1 Diabetes (T1DM) Patients Thought to Have LH
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Lipohypertrophy
Interventions: DEVICE: Medtronic Extended Infusion Set
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Web-app Constant-Care in Patients With Acute Severe Ulcerative Colitis Treated With Rescue Therapy
Status: UNKNOWN
Conditions: Ulcerative Colitis|Telemedicine
Interventions: DEVICE: Constant-Care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of an Infusion Therapy Nursing Expert Service on Length of Stay and Clinical Results of Venous Access Devices
Status: COMPLETED
Conditions: Patients With Prolonged Intravenous Therapy
Interventions: OTHER: Infusion therapy nursing expert service
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Study of Time Optimizing of Endoscopic Photodynamic Therapy on Esophageal and/or Gastric Cardiac Cancer
Status: UNKNOWN
Conditions: Stage I Esophageal Adenocarcinoma|Stage II Esophageal Adenocarcinoma|Stage III Esophageal Adenocarcinoma|Stage I Esophageal Squamous Cell Carcinoma|Stage II Esophageal Squamous Cell Carcinoma|Stage III Esophageal Squamous Cell Carcinoma
Interventions: DRUG: photosensitizer(photofrin)|DEVICE: 630 nm laser irradiation (DIOMED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma
Interventions: DRUG: nab-sirolimus|DRUG: nab-sirolimus + temozolomide|DRUG: nab-sirolimus + bevacizumab|DRUG: nab-sirolimus + lomustine|DRUG: nab-sirolimus + marizomib (MRZ)|DRUG: nab-sirolimus + temozolomide + radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Tolerability of AG013 in Oral Mucositis Compared to Placebo When Administered Three Times Per Day
Status: TERMINATED
Conditions: Oral Mucositis
Interventions: BIOLOGICAL: AG013|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DP-VPA for Migraine Prophylaxis, a Pilot Efficacy Study
Status: WITHDRAWN
Conditions: Migraine
Interventions: DRUG: DP-VPA|DRUG: DP-VPA Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-279 in Healthy Adults on the Effect on ECG Measurements
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: TAK-279|DRUG: TAK-279 Placebo|DRUG: Moxifloxacin|DRUG: Moxifloxacin Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Nefecon in Patients With Primary IgA (Immunoglobulin A) Nephropathy
Status: COMPLETED
Conditions: Primary IgA Nephropathy
Interventions: DRUG: Nefecon|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dietary Salicylate in Aspirin Exacerbated Respiratory Disease
Status: COMPLETED
Conditions: Chronic Rhinosinusitis|Aspirin Exacerbated Respiratory Disease|Asthma|Aspirin Sensitivity
Interventions: BEHAVIORAL: Low salicylate diet|BEHAVIORAL: Normal Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study to Assess the Effects of Multi Dose Clopidogrel on the Pharmacokinetics of Single-Dose K-877 in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: K-877|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)
Status: COMPLETED
Conditions: Aspergillosis
Interventions: DRUG: Posaconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Wound Healing After Lower 3rd Molar Fully-impacted Surgery With 2 Types of Flap
Status: UNKNOWN
Conditions: Wound Heal|Quality of Life|Dehiscence
Interventions: PROCEDURE: lower third molar extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Status: ACTIVE_NOT_RECRUITING
Conditions: Syndesmotic Injuries|Ligament Rupture|Bimalleolar Fractures|Trimalleolar Fractures
Interventions: DEVICE: Tight rope fixation|DEVICE: Tight rope fixation with an anterior inferior tibiofibular ligament (AITFL) repair augmentation with an internal brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: GVAX Pancreas Vaccine|DRUG: CRS-207|DRUG: CRS-207
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Possible Use of Rotigotine in Subjects 70 Years and Older With Late Onset of Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Rotigotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Text Messaging to Engage and Retain Veterans in Smoking Cessation Counseling
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: BEHAVIORAL: Text messaging prior to first counseling call|BEHAVIORAL: Text-to-Enhance|BEHAVIORAL: Mail Notice|BEHAVIORAL: Telephone Counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Asthmatic Patients to Determine if There is Any Difference in Dosing With Fluticasone Furoate/Vilanterol Inhalation Powder in the Morning or Evening on Lung Function
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF(100mcg)/Vilanterol(25mcg) AM|DRUG: FF(100mcg)/Vilanterol(25mcg) PM|DRUG: Placebo AM|DRUG: Placebo PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Intravenous Lidocaine on Clinical Outcomes of Patients With ARDS During COVID-19 Pandemia
Status: TERMINATED
Conditions: Acute Respiratory Distress Syndrome (ARDS)|COVID-19|Corona Virus Infection
Interventions: DRUG: Lidocaine 2%|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of High-Resolution Microendoscopy (HRME) in Patients With Cervical Dysplasia
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: DRUG: Proflavine|DEVICE: HRME Imaging|BEHAVIORAL: Phone Call|PROCEDURE: Colposcopy|DRUG: Acetic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Safety and Efficacy of Titanium-nitric Oxide-coated Stent (Optimax®) in Patients With Lesions With a Low Risk of Restenosis (Diameter ≥ 3.0 mm and Length ≤ 20 mm)
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Optimax stent®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: F15 Recharge Free Axonics SNM System Clinical Study
Status: RECRUITING
Conditions: Urinary Urge Incontinence (UUI)|Urinary Frequency (UF)|Fecal Incontinence (FI)
Interventions: DEVICE: Axonics SNM System (Model 4101)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Intensive Care Transitional Care, Rehabilitation, and Family-Support
Status: NOT_YET_RECRUITING
Conditions: Intensive Care Unit Syndrome|Disabilities Multiple|Critical Illness|Caregiver Burden
Interventions: OTHER: Post Intensive Care Transitions Rehabilitation and Family Support (PIC-TRFS)|OTHER: Enhanced Usual Care Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of an Internet-Based Insomnia Intervention to Prevent Cognitive Decline in Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Cognitive Impairment|Insomnia
Interventions: OTHER: Sleep Health Using the Internet for Older Adult Sufferers of Insomnia and Sleeplessness
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Safety and Tolerability of NOX66 in Healthy Volunteers
Status: WITHDRAWN
Conditions: Healthy Volunteers
Interventions: DRUG: Oral idronoxil suspension|DRUG: NOX66 (A)|DRUG: NOX66 (B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Microbiology of C16G2 Varnish Administered in Multiple Doses to Dental Subjects
Status: COMPLETED
Conditions: Dental Caries
Interventions: DRUG: C16G2 Varnish|DRUG: Placebo Varnish
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Effect of Repeated Administration of Diltiazem on the Pharmacokinetics of Darapladib (Sb-480848).
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: Darapladib|DRUG: Diltiazem
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Coping After Loss Through Mindfulness in Adults With Prolonged Grief Disorder
Status: ENROLLING_BY_INVITATION
Conditions: Prolonged Grief Disorder
Interventions: BEHAVIORAL: Meditation Training|BEHAVIORAL: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the CG ASSIST Program for Caregiving Dyads
Status: COMPLETED
Conditions: Transfer Impairment
Interventions: BEHAVIORAL: Immediate Intervention Group|OTHER: Delayed Intervention Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Lenalidomide in Pediatric Subjects With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid
Interventions: DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-eluting Balloon in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Coronary Artery Disease|Atherosclerosis|Thrombosis|Acute Myocardial Infarction
Interventions: DEVICE: Drug eluting balloon|DEVICE: Bare metal stent|DEVICE: Drug eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Fluzoparib in Healthy Subjects and Those With Impaired Liver Function
Status: COMPLETED
Conditions: Hepatic Impairment|Healthy Subjects
Interventions: DRUG: Fluzoparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
Status: COMPLETED
Conditions: Platelet-rich Fibrin
Interventions: OTHER: PRF|OTHER: standard third molar surgical removal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Ketamine-Induced Agitation, by Midazolam or Haloperidol Premedication After Adult Procedural Sedation
Status: COMPLETED
Conditions: Ketamine Induced Agitation
Interventions: DRUG: Midazolam|DRUG: Haloperidol|DRUG: placebo|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness Between Nutritional Counseling Monthly Phone Call Versus Self Help Informative Booklet
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: PROCEDURE: Counseling Monthly Phone Calls|PROCEDURE: Self Help Informative Booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Surgical Resection After Induction Treatment in Non-Small Cell Lung Cancer (SRaIT)
Status: COMPLETED
Conditions: Patient Outcome Assessment|Morbidity|Mortality
Interventions: PROCEDURE: Pulmonary parenchyma resection, lobectomy, pneumonectomy, sleeve lobectomy, extended lobectomy/pneumonectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A
Status: RECRUITING
Conditions: Temporomandibular Disorders
Interventions: DRUG: Botulinum toxin type A|DRUG: Isotonic saline 0,9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I/II, Open-label, Multi-center, Two Part Dose-escalation, Safety, Pharmacokinetics (PK) and Efficacy Study of AZD4877 in Patients With Acute Myelogenous Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia
Interventions: DRUG: AZD4877
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Carcinoma
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALY688-SR in Generally Healthy Overweight or Obese Adults
Status: TERMINATED
Conditions: Overweight and Obesity
Interventions: DRUG: ALY688-SR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research on Potential Biomarkers of Prediabetes and Diabetes Based on MALDI-TOF MS Platform.
Status: RECRUITING
Conditions: Prediabetes|Diabetes Mellitus|Gestational Diabetes Mellitus|Proteomics
Interventions: DIAGNOSTIC_TEST: Oral Glucose Tolerance Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Insulin Detemir|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety, Pharmacokinetics and Pharmacodynamics of NV1205 in Pediatric Male Subjects With Adrenoleukodystrophy
Status: WITHDRAWN
Conditions: X-Linked Adrenoleukodystrophy
Interventions: DRUG: Sobetirome (NV1205)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device
Status: RECRUITING
Conditions: Hypertension|Blood Pressure|Systolic Hypertension|Diastolic Hypertension|Essential Hypertension|Obstructive Sleep Apnea|Prehypertension
Interventions: DEVICE: CART-I Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
Status: COMPLETED
Conditions: Periodontitis|Dental Caries|Hypertension
Interventions: DRUG: analgesic mouth rinses (dissolved Aspirin)|DRUG: Normal saline rinses.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Vocational Rehabilitation for the Return to Work of Breast Cancer Patients: a Feasibility Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer|Breast Neoplasm
Interventions: OTHER: Multidisciplinary vocational rehabilitation intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fermented Wheat Germ Extract in Women With Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Cancer
Interventions: DRUG: Fermented Wheat Germ Extract (FWGE)|DRUG: Placebo|OTHER: Standard of Care: Planned Surgery|OTHER: Quality of Life (QoL) Surveys: FACT-O
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia
Status: RECRUITING
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: BIOLOGICAL: Pneumococcal 20-valent Conjugate Vaccine|BIOLOGICAL: Pneumococcal Polyvalent Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Role of Fluorothymidine Positron Emission Tomography (FLT-PET) in Proliferation of Colorectal Liver Metastases
Status: TERMINATED
Conditions: Colorectal Neoplasms|Liver Neoplasms
Interventions: PROCEDURE: FLT-PET scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Non-anesthesiologist Administered Propofol Sedation for Colonoscopy - a Randomized Clinical Trial
Status: COMPLETED
Conditions: Digestive System Diseases|Colonoscopy Sedation
Interventions: DRUG: Non-anesthesiologist propofol sedation|DRUG: Propofol sedation administered by an anesthesiologist|PROCEDURE: Colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility of Inspiratory Muscle Training in People With COPD Who Decline Pulmonary Rehabilitation
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: OTHER: Inspiratory Muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: Telaglenastat|DRUG: Famotidine|DRUG: Placebo for famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Immediate Versus Delayed Loading of Single Posterior Zirconia Implants
Status: RECRUITING
Conditions: Dental Implant Failed|Peri-implant Mucositis|Peri-Implantitis
Interventions: DEVICE: Zirconia implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Compare the Pharmacokinetics and Tolerability of CKD-348
Status: COMPLETED
Conditions: Hypertension|Dyslipidemias
Interventions: DRUG: CKD-348 F1|DRUG: CKD-348 F2|DRUG: CKD-828, D097, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RWE of Brentuximab Vedotin Consolidation in Patients With RR HL Who Receive Salvage Chemotherapy and ASCT
Status: RECRUITING
Conditions: Hodgkin Lymphoma, Adult|Relapsed Hodgkin's Disease, Adult|Refractory Hodgkin Lymphoma
Interventions: OTHER: Evaluation of therapeutical approach after ASCT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Carfilzomib in Combination w/Dexamethasone in Patients w/Newly Diagnosed Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Interleukin-5 (IL-5) Study for Hypereosinophilic Syndrome
Status: COMPLETED
Conditions: Hypereosinophilic Syndromes|Eosinophilic Gastroenteritis|Churg-Strauss Syndrome|Eosinophilic Esophagitis
Interventions: DRUG: Mepolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of the Endoscopic Removal of Large and Flat Colonic Polyps With LumenR RetractorTM
Status: COMPLETED
Conditions: Colonic Adenomatous Polyps
Interventions: DEVICE: LumenR Retractor|DEVICE: Removal without overtube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Solid Tumor
Status: UNKNOWN
Conditions: Advanced Solid Tumor
Interventions: DRUG: Mitoxantrone Hydrochloride Liposome, intravenous injection (IV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Kidney Tumors in Younger Patients
Status: RECRUITING
Conditions: Adult Cystic Nephroma|Anaplastic Kidney Wilms Tumor|Angiolipoma|Cellular Congenital Mesoblastic Nephroma|Classic Congenital Mesoblastic Nephroma|Clear Cell Sarcoma of the Kidney|Congenital Mesoblastic Nephroma|Cystic Partially Differentiated Kidney Nephroblastoma|Diffuse Hyperplastic Perilobar Nephroblastomatosis|Extrarenal Rhabdoid Tumor|Kidney Medullary Carcinoma|Kidney Neoplasm|Kidney Oncocytoma|Kidney Wilms Tumor|Metanephric Adenofibroma|Metanephric Adenoma|Metanephric Stromal Tumor|Metanephric Tumor|Mixed Congenital Mesoblastic Nephroma|Ossifying Renal Tumor of Infancy|Papillary Renal Cell Carcinoma|Renal Cell Carcinoma|Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions|Rhabdoid Tumor of the Kidney|Wilms Tumor
Interventions: OTHER: Cytology Specimen Collection Procedure|OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of Acetazolamide Versus Diazepam in Continuous Spike and Wave/Landau-Kleffner Syndrome
Status: TERMINATED
Conditions: Landau-Kleffner Syndrome|Status Epilepticus, Electrographic
Interventions: DRUG: Diazepam|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety, Tolerability, and Efficacy Study of IBI314 in Ambulatory Patients With COVID-19
Status: TERMINATED
Conditions: COVID-19
Interventions: BIOLOGICAL: IBI314|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)
Status: TERMINATED
Conditions: Type 1 Diabetes
Interventions: DRUG: Ramipril|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: VA Cultivating Access to Resources, Education, and Skills for Dementia Caregivers
Status: COMPLETED
Conditions: Dementia|Caregivers|Neurodegenerative Diseases|Brain Diseases
Interventions: BEHAVIORAL: Education and Skill-Building Rehabilitation (ESBR)|OTHER: Supplemental Education Materials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pocket Phantom Tool in Improving Accuracy of Quantitative PET/CT Imaging of Patients With Solid Tumors
Status: COMPLETED
Conditions: Adult Solid Neoplasm
Interventions: PROCEDURE: Computed Tomography|DEVICE: Imaging Phantoms|PROCEDURE: Positron Emission Tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Evaluate the Non-inferiority of Low-dose HIPEC Versus High-dose HIPEC in the Treatment of PMP (HIPEC-PMP)
Status: NOT_YET_RECRUITING
Conditions: Pseudomyxoma Peritonei
Interventions: DRUG: Mitomycin c
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow up Mesenchymal Stem Cell Therapy for Patients Virus-related Liver Cirrhosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: Autologous BM MSC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Glucose Clamp Study of Wockhardt's Human Isophane Insulin With Novolin N,in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes
Interventions: BIOLOGICAL: Wosulin N|BIOLOGICAL: Novolin N
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Rationalisation of Polypharmacy in the Elderly by the RASP Instrument
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Pharmaceutical care plan, mostly based on the RASP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dysphonia, Distress, and Perceived Control: Technology Based Assessment and Intervention
Status: RECRUITING
Conditions: Functional Dysphonia|Voice Disorders|Dysphonia
Interventions: BEHAVIORAL: VOICE Intervention Arm|BEHAVIORAL: Information-Only Arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Follow-Up at 6 Years of a Cohort of Children Born Very Prematurely
Status: COMPLETED
Conditions: Premature Birth
Interventions: DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of a New Type of Insulin in Participants With Type 2 Diabetes on Insulin Injection Therapy
Status: WITHDRAWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
Status: UNKNOWN
Conditions: Dexmedetomidine|Transurethral Resection of Prostate|Intravenous|Intrathecal
Interventions: DRUG: control group|DRUG: Intrathecal dexmedetomidine|DRUG: Intravenous dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Relaxin in the Treatment of Diffuse Scleroderma
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: Relaxin|DRUG: Relaxin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structured Physical Activity for Sleep Quality and Daytime Sleepiness in Patients With Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease|Poor Quality Sleep|Hypersomnia
Interventions: BEHAVIORAL: Structured Physical Activity|BEHAVIORAL: Sleep hygiene education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enzalutamide in Patients With Androgen Receptor Positive (AR+) Ovarian, Primary Peritoneal or Fallopian Tube Cancer and One, Two or Three Prior Therapies
Status: COMPLETED
Conditions: Advanced Epithelial Ovarian|Recurrent Epithelial Ovarian|Fallopian Tube|Primary Peritoneal Carcinoma
Interventions: DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Adult Solid Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pegfilgrastim|OTHER: Pharmacological Study|DRUG: Tivantinib|DRUG: Topotecan Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block and Postoperative Pain After Laparoscopic Cholecystectomy
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy|Postoperative Pain|Abdominal Muscles|Nerve Block
Interventions: PROCEDURE: Ultrasound guided subcostal TAP block|PROCEDURE: Placebo Ultrasound guided subcostal TAP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose IV Dexamethasone in Prolonging Caudal Anesthesia in Children Undergoing Genitourinary Surgery
Status: TERMINATED
Conditions: Surgery
Interventions: DRUG: Dexamethasone|DRUG: Ropivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Validation of Insulin Protocol for Glucocorticoid-induced Hyperglycemia in Diabetic Oncology Patients
Status: COMPLETED
Conditions: Lymphoma|Diabetes Mellitus, Type 2|Hyperglycemia
Interventions: BIOLOGICAL: Insulin protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Studer Pouch Versus the T-Pouch Orthotopic Neobladder Urinary Diversion in Bladder Cancer Patients
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: PROCEDURE: Studer Pouch orthotopic urinary diversion|PROCEDURE: T-Pouch orthotopic urinary diversion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa
Status: ENROLLING_BY_INVITATION
Conditions: Choroideremia|X-Linked Retinitis Pigmentosa
Interventions: GENETIC: BIIB111|GENETIC: BIIB112
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety Study of Two Repeat Doses of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults
Status: COMPLETED
Conditions: Lateral Canthal Lines|Crow's Feet|Facial Wrinkles
Interventions: DRUG: RT001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Surgery|Recurrent Nasopharyngeal Carcinoma
Interventions: PROCEDURE: Plasma radiofrequency ablation|PROCEDURE: Electrocautery block resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability Study of GSK1120212, a MEK Inhibitor, in Combination With Docetaxel, Erlotinib, Pemetrexed, Pemetrexed + Carboplatin, Pemetrexed + Cisplatin, or Nab-Paclitaxel
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Trametinib (GSK1120212)|DRUG: Docetaxel|DRUG: Erlotinib|DRUG: Pemetrexed|DRUG: Carboplatin|DRUG: nab-Paclitaxel|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing Potential Synergistic Effects of Albuterol and Caffeine on Metabolic Rate
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: 2mg of Albuterol|DRUG: 4mg of Albuterol|DRUG: 100mg of Caffeine|DRUG: 200mg of Caffeine|DRUG: Albuterol 2mg & Caffeine 100mg|DRUG: Albuterol 2mg and Caffeine 200mg|DRUG: Albuterol 4mg and Caffeine 100mg|DRUG: Albuterol 4mg and Caffeine 200mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparisons of Two Types of Robot Assisted Gait Training
Status: UNKNOWN
Conditions: Stroke|Robot Assisted Gait Training
Interventions: DEVICE: exoskeleton type robot|DEVICE: end-effector type robot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease
Status: NOT_YET_RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: Inclisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Traditional Turkish Military Music and Endoscopic Retrograde Cholangiopancreatography
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangio-Pancreatography|Anxiety|Pain
Interventions: OTHER: Music listening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Neoadjuvant mFOLFOXIRI Versus CRT in the EMVI Positive LARC
Status: RECRUITING
Conditions: Locally Advanced Rectal Cancer
Interventions: DRUG: mFOLFOXIRI|COMBINATION_PRODUCT: Chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Emotional and Oral Characteristics of Patients That Attend a Dental Consultation for the Extraction of Third Molars
Status: COMPLETED
Conditions: Anxiety and Fear
Interventions: OTHER: Trifold information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: IT or IA Infusion of PD1/PDL1/CTLA4 Inhibitors Versus IV for Immunotherapy of Head/Neck Cancers (HNC)
Status: RECRUITING
Conditions: Head/Neck Neoplasm
Interventions: DRUG: PD1/PDL1/CTLA4 inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Biphasic Insulin Aspart 30 in Type 1 or 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2
Interventions: DRUG: biphasic insulin aspart|DRUG: biphasic human insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Videophone Administered Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder
Status: COMPLETED
Conditions: Obsessive Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|BEHAVIORAL: Wait-list control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT