pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of 25-OH-Vitamin-D3 Substitution in Patients With Malignant and Immune-hematologic Diseases
Status: TERMINATED
Conditions: Chronic Lymphoid Leukemia
Interventions: DRUG: Cholecalciferol|DRUG: oleum neutralicum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Resonance Imaging for Lymph Node Staging in Ovarian Cancer
Status: WITHDRAWN
Conditions: Ovarian Neoplasms
Interventions: DRUG: Gadofosveset trisodium (Ablavar™ )|DEVICE: MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Diagnostic Time-Out: A Randomized Clinical Trial of a Checklist to Improve Diagnostic Accuracy
Status: COMPLETED
Conditions: Diagnostic Errors
Interventions: BEHAVIORAL: Diagnostic checklist|BEHAVIORAL: Usual care with no diagnostic checklist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy
Status: RECRUITING
Conditions: Male Infertility
Interventions: PROCEDURE: subinguinal varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.
Status: COMPLETED
Conditions: Keloid|Autologus Adipose Derived Stem Cells|Feasibility|Safety
Interventions: BIOLOGICAL: Autologous adipose derived stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Meloxicam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Continuous Control of Polyurethane Tracheal-cuff Pressure: Efficiency of a Pneumatic Device
Status: COMPLETED
Conditions: Mechanical Ventilation Complication|Tracheal Intubation Morbidity
Interventions: DEVICE: Pneumatic device, cylindrical or tapered cuff
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery
Status: COMPLETED
Conditions: Pancreatic Alpha Cell Carcinoma|Pancreatic Beta Islet Cell Carcinoma|Pancreatic Delta Cell Carcinoma|Pancreatic G-cell Carcinoma|Recurrent Islet Cell Carcinoma
Interventions: DRUG: temozolomide|DRUG: pazopanib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
Status: NOT_YET_RECRUITING
Conditions: Clostridium Difficile Infection Recurrence
Interventions: DIETARY_SUPPLEMENT: Bacillus velezensis DSM 33864|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety Study of co.Don Chondrosphere to Treat Cartilage Defects
Status: COMPLETED
Conditions: Articular Cartilage Lesion of the Femoral Condyle
Interventions: DRUG: co.don chondrosphere®|PROCEDURE: Microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Docetaxel With or Without AZD6244 in Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Docetaxel and AZD6244|DRUG: Docetaxel and placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Feasibility, Usability and Satisfaction of an Online Tool for Perinatal Mental Health Problems
Status: RECRUITING
Conditions: Depression|Depressive Disorder, Major|Depression, Postpartum|Anxiety|Anxiety Disorders|Pregnancy Related
Interventions: BEHAVIORAL: online psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep
Status: RECRUITING
Conditions: Insomnia, Primary
Interventions: DEVICE: Active cTBS|DEVICE: Sham cTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy
Status: COMPLETED
Conditions: Geographic Atrophy
Interventions: OTHER: Sham|DRUG: Lampalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Nanocrystalline Hydroxyapatite Versus Autogenous Bone Grafts : A Comparative Clinical Study in Alveolar Cleft Grafting
Status: UNKNOWN
Conditions: Alveolar Cleft
Interventions: PROCEDURE: secondary alveolar bone graft|PROCEDURE: harvesting of the autogenous bone graft|PROCEDURE: Nanocrystalline Hydroxyapatite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Analgesic Efficacy of Oral Glucose in Preterm Neonates During Suctioning
Status: UNKNOWN
Conditions: Analgesia
Interventions: DRUG: Glucose 20%|DRUG: Aqua
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sucralose in Subjects With Diabetes Mellitus Insulin Requesting
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Sucralose|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Disposition of Drug in Body and Safety After Administration of Single Inhaled Doses of Drugs Abediterol and AZD7594 Administered Alone, in Fixed Dose Combination and in Free Combination Using the Dry Powder Inhaler in Healthy Male Participants
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)|Asthma
Interventions: DRUG: Abediterol|DRUG: AZD7594|DRUG: AZD7594/abediterol|DRUG: AZD7594 and abediterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of a Comprehensive Visceral Adiposity-Focused Anti-Obesity Program
Status: COMPLETED
Conditions: Obesity|Obesity, Morbid|Obesity, Visceral|Central Obesity|Metabolic Disease|Hypertension|Dyslipidemias|Type 2 Diabetes|Visceral Obesity
Interventions: OTHER: 20Lighter anti-obesity program
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide
Status: COMPLETED
Conditions: Drug Interaction Potentiation
Interventions: DRUG: Vadadustat|DRUG: Furosemide|DRUG: Adefovir|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multifamily Group Psychoeducation for SUD's in Turkey
Status: COMPLETED
Conditions: Disease|Mental Disorders, Severe|Substance-Related Disorders|Substance Use Disorders|Alcohol Use Disorder
Interventions: OTHER: multifamily group psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Antidepressant Effects Of The NMDA Antagonist, CP-101,606, In Patients With MDD
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: NMDA Antagonist, CP-101,606 (traxoprodil)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Hortitherapy on the Immediate Well-being of Elderly People With Alzheimer's Disease or Related in Day Care
Status: UNKNOWN
Conditions: Horticultural Therapy
Interventions: BEHAVIORAL: hortitherapy in people living with Alzheimer's taking place in three different day care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Danish Observational Study of Everolimus Plus Exemestane in Hormone Receptor (HR) Positive, Human Epidermal Growth Factor 2 (HER2) - Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Everolimus and exemestane
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: Dual-Energy Contrast-Enhanced Spectral Mammography (CESM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: FamilieTrivsel i Almen Praksis: a Mentalisation Programme for Families With Young Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Parent-Child Relations|Child Development|Parenting
Interventions: BEHAVIORAL: FamilieTrivsel|OTHER: enhanced care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Bone Marrow Samples From Patients With Acute Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: GENETIC: gene expression analysis|GENETIC: mutation analysis|GENETIC: polymorphism analysis|GENETIC: protein analysis|OTHER: flow cytometry|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Study of Increased Dose of TA-650 in Patients With Psoriasis
Status: COMPLETED
Conditions: Plaque Psoriasis|Psoriatic Arthritis|Pustular Psoriasis (Excluding a Localized)|Psoriatic Erythroderma
Interventions: DRUG: TA-650
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Canagliflozin in Postprandial Hyperinsulinemic Hypoglycemia (CANA-PHH-RYGB)
Status: UNKNOWN
Conditions: Postprandial Hypoglycemia
Interventions: DRUG: Canagliflozin 300 MG Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Auricular Vagus Stimulation and STEMI
Status: RECRUITING
Conditions: Vagus Nerve Stimulation|Acute Coronary Syndrome|Ischemia Reperfusion Injury
Interventions: DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Pemetrexed and Carboplatin in Patients With Recurrent Ovarian or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Cancer|Primary Peritoneal Cancer
Interventions: DRUG: Pemetrexed - Phase 1|DRUG: Carboplatin - Phase 1|DRUG: Pemetrexed - Phase 2|DRUG: Carboplatin - Phase 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Esophagus|Adenocarcinoma of the Gastroesophageal Junction|Diffuse Adenocarcinoma of the Stomach|Intestinal Adenocarcinoma of the Stomach|Mixed Adenocarcinoma of the Stomach|Recurrent Esophageal Cancer|Recurrent Gastric Cancer|Squamous Cell Carcinoma of the Esophagus|Stage III Esophageal Cancer|Stage IIIA Gastric Cancer|Stage IIIB Gastric Cancer|Stage IIIC Gastric Cancer|Stage IV Esophageal Cancer|Stage IV Gastric Cancer
Interventions: BIOLOGICAL: oblimersen sodium|DRUG: cisplatin|DRUG: fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Relapsed Non Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma
Interventions: DRUG: Loncastuximab tesirine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Ontogeny of P-glycoprotein Expression in Blood of Pediatric Leukemic Patients
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia
Interventions: OTHER: MTX, (but the investigator is not using any intervention, the participants are already taking it in their treatment protocol and the investigator is just analyzing p-gp expression)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001|DRUG: TOK-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Volume Washing of the Abdomen in Increasing Survival After Surgery in Patients With Pancreatic Cancer That Can Be Removed by Surgery
Status: RECRUITING
Conditions: Acinar Cell Carcinoma|Ampulla of Vater Adenocarcinoma|Cholangiocarcinoma|Duodenal Adenocarcinoma|Pancreatic Adenocarcinoma|Pancreatic Ductal Adenocarcinoma|Pancreatic Intraductal Papillary Mucinous Neoplasm|Periampullary Adenocarcinoma
Interventions: PROCEDURE: Pancreatectomy|OTHER: Lavage|PROCEDURE: Pancreatectomy|OTHER: Lavage|PROCEDURE: Pancreatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Assess Safety, Tolerability and PK of AZD3199 in Japanese
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AZD3199 Turbuhaler®|DRUG: Placebo Turbuhaler®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of RV6153
Status: TERMINATED
Conditions: Asthma|Healthy Volunteers
Interventions: DRUG: RV6153 single dose|DRUG: RV6153 matching placebo single dose|DRUG: RV6153 14 day repeat dose|DRUG: RV6153 matching placebo 14 day repeat dose|DRUG: RV6153 28 day repeat dose|DRUG: RV6153 matching placebo 28 day repeat dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11
Status: COMPLETED
Conditions: Opioid-Related Disorders|Substance-Related Disorders
Interventions: DRUG: 15 % Nitrous oxide|DRUG: 0.3 % Sevoflurane|DRUG: 30% Nitrous oxide|DRUG: 0.6% Sevoflurane|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Study of Pembrolizumab, Radiation and Immune Modulatory Cocktail in Cervical/Uterine Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Uterine Cancer
Interventions: DRUG: Pembrolizumab|RADIATION: Radiation|DRUG: Vitamin D|DRUG: Aspirin|DRUG: Lansoprazole|DRUG: Cyclophosphamide|DIETARY_SUPPLEMENT: Curcumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
Status: UNKNOWN
Conditions: Multilevel Cervical Spinal Stenosis|Single Brachial Radiculopathy
Interventions: PROCEDURE: Bilateral approach for Laminoplasty|PROCEDURE: Unilateral approach for laminoplasty|PROCEDURE: Subperiosteal approach for foraminotomy|PROCEDURE: Transmuscular approach for foraminotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DRUG: Intravenous infusion of DMT|DRUG: Intravenous infusion of ketamine|DRUG: Intravenous infusion of placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: PF-04447943|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Inspiratory Oxygen Fraction for Preoxygenation
Status: TERMINATED
Conditions: Intraoperative Complications|Respiratory Complication|Oxygen Toxicity|Oxygen Deficiency|Anesthesia
Interventions: PROCEDURE: Pure oxygen group|PROCEDURE: Lower oxygen group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cord Clamping Among Neonates With Congenital Heart Disease
Status: RECRUITING
Conditions: Congenital Heart Disease (CHD)
Interventions: PROCEDURE: Umbilical Cord Clamping at ~30 seconds|PROCEDURE: Umbilical Cord Clamping at ~120 seconds|PROCEDURE: Umbilical Cord Milking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quality of Life in Advanced Gastric Cancer Patients Receiving Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: QOL; Quality of Life;Gastric Cancer; Gastrectomy;Neoadjuvant Chemotherapy
Interventions: DRUG: Neoadjuvant Chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis
Status: RECRUITING
Conditions: Non-Tuberculous Mycobacterial Pneumonia|Cystic Fibrosis Lung
Interventions: OTHER: Luminex; scRNAsec
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Whey Protein Supplements on Markers of Exercise-induced Muscle Damage in Resistance-trained Individuals
Status: COMPLETED
Conditions: Muscle Damage|Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Pasture-raised whey protein|DIETARY_SUPPLEMENT: Conventional whey protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)
Status: COMPLETED
Conditions: Rheumatoid Arthritis (RA)
Interventions: DRUG: Peficitinib|DRUG: Plaebo|DRUG: Disease-modifying antirheumatic drugs (DMARDs)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Replacement Therapy in the Intensive Care Unit
Status: COMPLETED
Conditions: Delirium|Psychomotor Agitation|Substance Withdrawal Syndrome|Nicotine Replacement Therapy
Interventions: DRUG: Transdermal nicotine patch|OTHER: Cutaneous patch, containing no active substances
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab
Status: RECRUITING
Conditions: Breast Cancer Triple Negative|Breast Cancer Stage II|Breast Cancer Stage III|Breast Cancer Invasive
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Lithium as a Glycogen-Synthase-Kinase-3 (GSK-3) Inhibitor in Mild Cognitive Impairment
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of tDCS Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenic Patients
Interventions: DEVICE: Transcranial direct current stimulation (tDCS)-anodal group|DEVICE: Transcranial direct current stimulation (tDCS)-sham group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Microbiologic Response With Linezolid And Vancomycin In Ventilator-Associated Pneumonia Due To Methicillin Resistant Staphylococcus Aureus
Status: COMPLETED
Conditions: Pneumonia, Ventilator-Associated
Interventions: DRUG: Vancomycin|DRUG: Linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Iliopsoas Muscle Space Block Versus Supra-iliac Anterior Quadratus Lumborum Block in Total Hip Arthroplasty
Status: RECRUITING
Conditions: Hip Arthropathy
Interventions: PROCEDURE: control|PROCEDURE: IPS|PROCEDURE: Supra-iliac QL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Status: COMPLETED
Conditions: Anxiety, Dental|Dental Decay
Interventions: COMBINATION_PRODUCT: Regimen 1|COMBINATION_PRODUCT: Regimen #2|COMBINATION_PRODUCT: Regimen #3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety and Tolerability of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA).
Status: TERMINATED
Conditions: Spinal Muscular Atrophy
Interventions: DRUG: Nusinersen|PROCEDURE: Sham Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Electrical Nerve Stimulation (TENS) in Chronic Pain, Responders and Non-Responders?
Status: UNKNOWN
Conditions: Neck Pain|Lower Back Pain|Shoulder Pain
Interventions: DEVICE: TENStemeco Schwa Medico [Transcutaneous Electrical Nerve Stimulation (TENS)]
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Using the Non Invasive Technology Magnetic Resonance Elastography for the Diagnosis of Liver Fibrosis Stage
Status: UNKNOWN
Conditions: Liver Diseases
Interventions: DEVICE: MRE (Magnetic Resonance Elastography)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study on Metabolic Effects of Fish Peptides and Vitamin D
Status: COMPLETED
Conditions: Prediabetes|Insulin Resistance
Interventions: DIETARY_SUPPLEMENT: Fish peptide supplement|DIETARY_SUPPLEMENT: Vitamin D supplement|DIETARY_SUPPLEMENT: Fish peptide + Vitamin D3 supplements|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Safety and Efficacy of Daclatasvir/Sofosbuvir/Ribavirin for 16 Versus 24 Weeks for HCV Genotype 3 Cirrhotics
Status: COMPLETED
Conditions: Hepatitis C|Cirrhosis
Interventions: DRUG: daclatasvir|DRUG: Sofosbuvir, Sovaldi|DRUG: Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2a, AMP Challenge, Dose Escalation Study to Assess the Dose Response for Topical Efficacy and Systemic Activity in Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone furoate (FF) Dry Powder Inhaler|DRUG: Fluticasone propionate (FP) Dry Powder Inhaler|DRUG: Budesonide (BUD) Turbuhaler|DRUG: Placebo (ELLIPTA or DISKUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Evaluating the Safety and Efficacy of Intravenous CD-801 in Treating Advanced HCC Patients
Status: NOT_YET_RECRUITING
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: CD-801
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure
Status: UNKNOWN
Conditions: Heart Failure|Renal Insufficiency
Interventions: DRUG: Levosimendan in addition to standard therapy|DRUG: spironolactone, beta-blockers,ecc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine to Levobupivacaine for Transversus Abdominis Plane Block in Elderly Patients Undergoing Inguinal Hernia Repair Surgery
Status: COMPLETED
Conditions: Dexmedetomidine|Fentanyl
Interventions: DRUG: Levobupivacaine|DRUG: Dexmedetomidine Hydrochloride|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Ruxolitinib in Patients With Primary Myelofibrosis (PM), Post-polycythemia Vera (PV) Myelofibrosis, or Post-essential Thrombocythemia (ET) Myelofibrosis
Status: COMPLETED
Conditions: Primary Myelofibrosis (MF)
Interventions: DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses
Status: COMPLETED
Conditions: Drug Overdose|Opioid-Related Disorders|Drug Addiction|Drug Abuse|Substance Abuse
Interventions: BEHAVIORAL: Peer Intervention|DRUG: naloxone nasal spray kit|BEHAVIORAL: Personally-tailored opioid overdose prevention education (information packet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Polyethylene Glycol 3350 (PEG 3350) for Relief of Constipation (MK-8114-005)
Status: WITHDRAWN
Conditions: Constipation
Interventions: DRUG: Polyethylene Glycol 3350 Powder for Solution (PEG 3350)|DRUG: Polyethylene Glycol 4000 Powder for Solution (PEG 4000)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Event-Related Potential (ERP) Components in Clinical Diagnosis
Status: RECRUITING
Conditions: Alzheimer Disease|Dementia, Mild|Mild Cognitive Impairment
Interventions: DEVICE: Electroencephalogram (EEG) system|BEHAVIORAL: Standard Neuropsychological Testing|BEHAVIORAL: Additional neuropsychological tests
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Testosterone and Fat Utilization
Status: COMPLETED
Conditions: Healthy|Volunteers
Interventions: DRUG: GnRH antagonist|DRUG: Aromatase Inhibitors|DRUG: Testosterone gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pre- Versus Post-incisional Pregabalin for Postoperative Pain Attenuation and Analgesics Spare in Orthopedic Oncologic Patients
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Pregabalin|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Physiological Effects of New Polyphenol-enriched Foods in Humans
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: free curcumin|OTHER: encapsulated curcumin|OTHER: encapsulated curcumin + PQG|OTHER: free cocoa polyphenol|OTHER: encapsulated cocoa polyphenols|OTHER: control nut cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis
Status: COMPLETED
Conditions: Recurrent Herpes Simplex Labialis
Interventions: DRUG: Vehicle versus NB-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Madres Para la Salud (Mothers for Health)
Status: COMPLETED
Conditions: Overweight and Obesity|Depression, Postpartum|Mother (Person)
Interventions: BEHAVIORAL: Madres para la Salud
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immune Responses in Adults to Revaccination With ADACEL® 10 Years After a Previous Dose
Status: COMPLETED
Conditions: Pertussis|Tetanus|Diphtheria
Interventions: BIOLOGICAL: Tetanus, Reduced Diphtheria Toxoid and Acellular Pertussis (ADACEL®)|BIOLOGICAL: Tetanus, Reduced Diphtheria Toxoid and Acellular Pertussis (ADACEL®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transplantation of Autologous Stem Cells for the Treatment of Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 1|Autoimmune Diseases|Endocrine System Diseases|Glucose Metabolism Disorders|Immune System Diseases|Metabolic Diseases
Interventions: BIOLOGICAL: Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Latency Reversal With High Dose Disulfiram Plus Vorinostat in HIV-infected Individuals on ART
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: Disulfiram, (National Drug Code) NDC 0378-4141-01|DRUG: Vorinostat, NDC 00006-0568-40
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Tumor Tissue Samples From Patients Who Have Undergone Surgery for Advanced Stage III or Stage IV Ovarian Epithelial Cancer
Status: RECRUITING
Conditions: Stage IIIA Ovarian Cancer|Stage IIIB Ovarian Cancer|Stage IIIC Ovarian Cancer|Stage IV Ovarian Cancer
Interventions: OTHER: Laboratory Biomarker Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Efficacy and Safety of Rifaximin Treatment
Status: RECRUITING
Conditions: Liver Failure, Acute on Chronic|Hepatic Encephalopathy|HBV|Hepatitis B|Rifaximin|Effect of Drug
Interventions: DRUG: Rifaximin 200 mg|OTHER: Standard Treatment without Rifaximin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Japanese Study Evaluating the Effects of Telithromycin in Children With Community-Acquired Pneumonia
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Telithromycin (HMR3647)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of RO7515629 in Participants With HLA-G Positive Solid Tumors
Status: TERMINATED
Conditions: Renal Cell Carcinoma|Non-small Cell Lung Cancer|Pancreatic Adenocarcinoma|Colorectal Cancer|Ovarian Neoplasms
Interventions: DRUG: RO7515629|DRUG: tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Liraglutid, Dapagliflozin and Acarbose on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in Overweight/Obese T2DM Patients Controlled Inadequately With Metformin Monotherapy.
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Obesity|Cognitive Impairment
Interventions: DRUG: Liraglutid|DRUG: Dapagliflozin|DRUG: Acarbose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine For Acute Treatment of Pain in Emergency Department
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Efficacy of Enterade (VS001) in Children at Risk for Environmental Enteric Dysfunction in Bangladesh
Status: COMPLETED
Conditions: Environmental Enteric Dysfunction
Interventions: DIETARY_SUPPLEMENT: Enterade|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Good and Bad Effects of BIBF1120 in Small Cell Lung Cancer Patients Who Have Previously Benefited From First-line Platinum-based Chemotherapy
Status: WITHDRAWN
Conditions: Small Cell Lung Cancer|Platinum-sensitive
Interventions: DRUG: BIBF1120
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Rhythm and Music-based Therapy Program and Therapeutic Riding in Late Recovery Phase Following Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: OTHER: RGRM|OTHER: Therapeutic riding|OTHER: Receives no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent
Status: WITHDRAWN
Conditions: Malignant Ovarian Clear Cell Tumor|Malignant Ovarian Serous Tumor|Recurrent Fallopian Tube Carcinoma|Recurrent Ovarian Carcinoma|Recurrent Primary Peritoneal Carcinoma|Stage IIIA Fallopian Tube Cancer|Stage IIIA Ovarian Cancer|Stage IIIA Primary Peritoneal Cancer|Stage IIIB Fallopian Tube Cancer|Stage IIIB Ovarian Cancer|Stage IIIB Primary Peritoneal Cancer|Stage IIIC Fallopian Tube Cancer|Stage IIIC Ovarian Cancer|Stage IIIC Primary Peritoneal Cancer|Stage IV Fallopian Tube Cancer|Stage IV Ovarian Cancer|Stage IV Primary Peritoneal Cancer
Interventions: BIOLOGICAL: Aldesleukin|BIOLOGICAL: HER2Bi-Armed Activated T Cells|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avatrombopaq In Patients With Cirrhosis
Status: UNKNOWN
Conditions: Thrombocytopenia; Drugs|Cirrhosis, Liver|Procedural Bleeding
Interventions: DRUG: Doptelet Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Evaluating the Effect of R-mabHDI in Lymphocytic Predominant Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: R-mabHDI and ABVD|DRUG: ABVD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment With Azacitidine of Recurrent Gliomas With IDH1/2 Mutation
Status: ACTIVE_NOT_RECRUITING
Conditions: Recurrent IDH1/2 Mutated Glioma
Interventions: DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Active and Passive Distraction Techniques on Reducing Fear and Anxiety and Improving Oral Health Knowledge of Children Undergoing Extraction in the Dental Operatory- A Randomized Controlled Trial
Status: UNKNOWN
Conditions: Fear Anxiety
Interventions: BEHAVIORAL: Video game distraction and video distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implantable Loop Recorder Versus Conventional Ambulatory Monitoring in Detecting Atrial Fibrillation After Pulmonary Vein Isolation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Implantable loop recorder (ILR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Status: UNKNOWN
Conditions: Stevens-Johnson Syndrome|Toxic Epidermal Necrolyses|Ocular Surface Disease|Meibomitis|Meibomian Gland Dysfunction|Dry Eye
Interventions: DEVICE: Maskin Probe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Satisfaction in Patients Receiving PegIntron Pen/Rebetol for Hepatitis C (Study P04067)
Status: COMPLETED
Conditions: Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alfa-2b (SCH 54031)|DRUG: Ribavirin (SCH 18908)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Erlotinib Plus Bevacizumab in Hepatocellular Carcinoma (HCC) as Second-line Therapy
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: Bevacizumab|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylaxis Against DVTs After Primary Hip and Knee Replacement Surgery
Status: UNKNOWN
Conditions: Pulmonary Embolism
Interventions: DRUG: warfarin|DRUG: Fondaparinux:|DRUG: warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of The Safety And Efficacy Of Lyrica In The Treatment Of Newly Diagnosed Partial Epilepsy
Status: COMPLETED
Conditions: Epilepsy, Partial
Interventions: DRUG: Pregabalin|DRUG: Lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Lansoprazole in Preventing Aspirin-Induced Gastric and Duodenal Ulcers
Status: TERMINATED
Conditions: Stomach Ulcer|Duodenal Ulcer
Interventions: DRUG: Lansoprazole|DRUG: Gefarnate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hospital-Level Care at Home for Acutely Ill Adults
Status: COMPLETED
Conditions: Infection|Heart Failure|COPD|Asthma|Gout Flare|Chronic Kidney Diseases|Hypertensive Urgency|Atrial Fibrillation Rapid|Anticoagulants; Increased
Interventions: OTHER: Home hospitalization|OTHER: Traditional inpatient hospitalization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A+C in Metastatic Lung Adenocarcinoma Cancer
Status: UNKNOWN
Conditions: Lung Adenocarcinoma Metastatic
Interventions: DRUG: Crizotinib, bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Analgesia Following Wisdom Teeth Removal: Ropivacaine Versus Placebo
Status: COMPLETED
Conditions: Third Molar Extraction
Interventions: DRUG: Placebo injection|DRUG: Ropivacaine injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Candesartan as an Adjunctive Treatment for Bipolar Depression
Status: WITHDRAWN
Conditions: Bipolar Disorder Depression
Interventions: DRUG: Candesartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antiinflammatoric and Antioxidative Effect of Melatonin in Human Endotoxaemia
Status: COMPLETED
Conditions: Human Endotoxaemia
Interventions: DRUG: Melatonin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Mantle Cell Lymphoma (MCL)
Interventions: DRUG: Acalabrutinib|DRUG: Venetoclax|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pharyngeal Packing on Postoperative Gastric Volume in Patients Undergoing Nasal Surgery
Status: COMPLETED
Conditions: Anesthesia|Nasal Surgery|Pharyngeal Packing|Gastric Volume|Postoperative Nausea
Interventions: DEVICE: Pharyngeal packing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Leg Elevation on Prevention of Intraoperative Hypotension During Beach Chair Position
Status: COMPLETED
Conditions: Intraoperative Hypotension|Cerebral Ischemia|Shoulder Disease
Interventions: PROCEDURE: leg elevation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Subcutaneous Immunoglobulin Treatment of Patients With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Status: COMPLETED
Conditions: Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Interventions: DRUG: Subcutaneous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Affect Treatment for Depression and Anxiety (TAD Pilot)
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Positive Affect Treatment|BEHAVIORAL: Positive Affect Treatment and Negative Affect Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of High-Calorie Formula on Nutritional and Clinical Outcomes Among Infants After Congenital Heart Surgery
Status: COMPLETED
Conditions: Congenital Heart Disease in Children|Malnutrition, Child
Interventions: DIETARY_SUPPLEMENT: High-calorie density formula (1 kcal/ml)|DIETARY_SUPPLEMENT: Standard formula (0.67 kcal/ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Robotic-Assisted Laparoscopic Extended Pelvic Lymph Node Dissection for Transitional Cell Carcinoma of the Bladder
Status: COMPLETED
Conditions: Bladder Cancer
Interventions: PROCEDURE: Robotic-assisted laparoscopic surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fentanyl for Breakthrough Pain in the Emergency Department
Status: TERMINATED
Conditions: Pain
Interventions: DRUG: Fentanyl Nasal Spray|DRUG: Hydromorphone PCA|OTHER: Placebo Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of AMG 386 Plus Paclitaxel With or Without Bevacizumab as First Line Therapy in Her2-Negative Breast Cancer Patients
Status: COMPLETED
Conditions: Locally Recurrent and Metastatic Breast Cancer
Interventions: DRUG: AMG 386 Placebo|DRUG: AMG 386|DRUG: Bevacizumab|DRUG: AMG 386|DRUG: AMG 386|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lestaurtinib, Cytarabine, and Idarubicin in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: cytarabine|DRUG: idarubicin|DRUG: lestaurtinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Locally Advanced or Metastatic Transitional Cell Carcinoma With Cabazitaxel
Status: COMPLETED
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: Cabazitaxel|OTHER: Best Supportive Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT