pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Smoker Extracellular Vesicles Influence on Human Bronchial Epithelial Cells
Status: COMPLETED
Conditions: Smokers|Human Bronchial Epithelial Cells|Lung Pathogenesis|Biomarkers
Interventions: DIAGNOSTIC_TEST: Broncho Alveolar Lavages (BAL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repetitive Transcranial Magnetic Stimulation for Treating Resistant Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DEVICE: Magstim Rapid2 Stimulator|DEVICE: Magstim Rapid2 Stimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Giving Immunizations Through Vaccine Education
Status: COMPLETED
Conditions: HPV Vaccines
Interventions: BEHAVIORAL: Family Decision Support|BEHAVIORAL: Clinician Decision Support|OTHER: Family Decision Support and Clinician Decision Support|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Acute Supplementation With Beta-Alanine Improves Performance in Aerobic-anaerobic Transition Zones in Endurance Athletes
Status: COMPLETED
Conditions: Beta-alanine
Interventions: DIETARY_SUPPLEMENT: beta alanine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fine Needle Aspiration (FNA) Evaluation of the Intrahepatic HBV Reservoir and Its Immunological Characteristics in Chronically HBV-infected Patients
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: PROCEDURE: Investigation of the intrahepatic compartment using the fine needle aspiration (FNA) technique|BIOLOGICAL: Creation of a serum biobank|OTHER: FNA feasibility and acceptability questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Reflexology on Pain Management in Newborns
Status: COMPLETED
Conditions: Pain, Procedural|Pain, Acute|Analgesia
Interventions: PROCEDURE: Reflexology|PROCEDURE: Sucrose %24|PROCEDURE: Kangaroo care|PROCEDURE: Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ixazomib Citrate, Lenalidomide, and Dexamethasone in Treating Patients With POEMS Syndrome
Status: ACTIVE_NOT_RECRUITING
Conditions: Plasmacytoma|POEMS Syndrome
Interventions: DRUG: Dexamethasone|DRUG: Ixazomib Citrate|DRUG: Lenalidomide|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Protocol of the Installation of Knee Unicompartmental Prosthesis (Journey (Smith & Nephew)) With Mechanical Ancillary Versus Robotic Assisted (Navio System).
Status: COMPLETED
Conditions: Osteoarthritis Of Knee
Interventions: PROCEDURE: internal PUC implanted with mechanical ancillary|PROCEDURE: Internal PUC implanted with robotic assistance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing Doxazosin to Treat Stress Mechanisms in Alcoholism
Status: COMPLETED
Conditions: Alcoholism
Interventions: DRUG: Doxazosin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Early Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Taxane|DRUG: Letrozole|DRUG: Abemaciclib|DRUG: LHRH Analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eponychial Stent Study
Status: COMPLETED
Conditions: Eponychial Stent|Nail Bed Injury
Interventions: PROCEDURE: Nail bed repair with eponychial sent|PROCEDURE: Nail bed repair without eponychial stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Regeneration Using Vitamin A and PRF Compared to PRF Alone Treating Intra-bony Defects
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: BIOLOGICAL: Platelet Rich Fibrin (PRF)|BIOLOGICAL: Platelet Rich Fibrin (PRF) and Retinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Oculomotor Exercise on Writing Capabilities on Autism
Status: UNKNOWN
Conditions: Autism
Interventions: OTHER: visual motor integration group|OTHER: Handwriting intervention programs|OTHER: visual motor integration program and Handwriting intervention programs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: MV-NIS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effects of Hamstring Stretching Alone or Combined With Myofascial Release
Status: RECRUITING
Conditions: Hamstring Injury|Masseter|Myofascial Release|Stretching|Surface EMG|Temporomandibular Joint Disorders
Interventions: PROCEDURE: Static stretching|PROCEDURE: Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DFS and QOL After Modified Radical Mastectomy vs. Expanded Mckissock Surgery for EIC of the Breast
Status: RECRUITING
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Expanded Mckissock surgery|PROCEDURE: Modified radical mastectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing the Pharmacokinetics, Safety, and Efficacy of RPH-075 and Keytruda® in Patients With Malignant Neoplasms
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Melanoma|Squamous Non-small-cell Lung Cancer|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: RPH-075|DRUG: Keytruda®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Chronic Myelogenous Leukemia or Recurrent Acute Leukemia
Status: COMPLETED
Conditions: Leukemia|Neutropenia
Interventions: BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Topical Diclofenac Efficacy in Symptomatic Relief of Temporomandibular Degenerative Joint Disease
Status: COMPLETED
Conditions: Temporomandibular Degenerative Joint Disease
Interventions: DRUG: 1.5% diclofenac in 45.5% DMSO (topical treatment)|DRUG: 45.5% DMSO (topical placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study Of The Safety And Effects Of One Or More Doses Of HSP-130 Injected Under The Skin In Women With Breast Cancer That Has Not Spread To Distant Sites In The Body.
Status: COMPLETED
Conditions: Non-metastatic Breast Cancer
Interventions: DRUG: HSP-130
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Novel Controlled Hypo-Perfusion Technique in Partial Nephrectomy
Status: TERMINATED
Conditions: Partial Nephrectomy|Renal Cell Carcinoma
Interventions: PROCEDURE: Hypoperfusion of renal artery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Capacity of VAK694 When Combined With Allergen Immunotherapy to Bring About Specific Immune Tolerance
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: VAK694; Alutard Avanz SQ|DRUG: VAK694 placebo infusion; Alutard Avanz SQ|DRUG: VAK694 placebo infusion; Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology
Status: COMPLETED
Conditions: Microtia|Microtia-Anotia|Craniofacial Microsomia|Goldenhar Syndrome|OAVS|OAV Syndrome|Hemifacial Microsomia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Determine the Optimal Biologic Dose of CC-401 in Subjects With High-Risk Myeloid Leukemia
Status: TERMINATED
Conditions: Myeloid Leukemia
Interventions: DRUG: CC-401
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spyglass+RFA Versus Cytobrush+RFA for Extrahepatic Cholangiocarcinoma
Status: ENROLLING_BY_INVITATION
Conditions: Extrahepatic Cholangiocarcinoma|Malignant Biliary Obstruction
Interventions: PROCEDURE: Spyglass + RFA|PROCEDURE: Cytobrush + RFA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Arm Training in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Arm training program|BEHAVIORAL: Purdue pegboard test (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of a Specific Spice on Energy Metabolism
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Mustard (dijon)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Successful Extubation and Noninvasive Ventilation in Preterm ≤ 1500g Terms
Status: COMPLETED
Conditions: Respiratory Distress Syndrome In Premature Infants
Interventions: DEVICE: NIPPV|DEVICE: Bubble NCPAP|DEVICE: Ventilator NCPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Monitor Liver Diseases Dynamically by Ultrasound Viscoelasticity
Status: UNKNOWN
Conditions: Cirrhosis|Liver Diseases
Interventions: DEVICE: ultrasound viscoelasticity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multicenter Investigation of Limitation of Infarct Size (MILIS)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: propranolol|DRUG: hyaluronidase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Open-label, Two-way Crossover Trial to Determine the Pharmacokinetics of Metoclopramide When Administered as the Orally Disintegrating Tablet Compared to Reglan® Tablets in Subjects With Diabetic Gastroparesis
Status: COMPLETED
Conditions: Diabetic Gastroparesis
Interventions: DRUG: Reglan ODT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Suicidality in Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Disorder|Major Depressive Episode|Suicidal Ideation
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization of Treatment Strategy for Unresectable cN3 Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Tirelizumab|DRUG: Nab paclitaxel|DRUG: Carboplatin|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Safety (SCAMP)
Status: COMPLETED
Conditions: Complicated Intra Abdominal Infections
Interventions: DRUG: ampicillin and metronidazole and gentamicin|DRUG: ampicillin and gentamicin and clindamycin|DRUG: gentamicin and Piperacillin- tazobactam|DRUG: standard of care antibiotics and metronidazole|DRUG: metronidazole, clindamycin, or piperacillin-tazobactam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Microneedling Combined With Botulinum Toxin-A Versus Meso-Botox Injection in the Treatment of Atrophic Acne Scars: A Split-face Comparative Study
Status: RECRUITING
Conditions: Atrophic Acne Scar
Interventions: DRUG: Meso-botox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transversus Abdominis Plane Block in Children Undergoing Open Pyeloplasty Surgery
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Transversus Abdominis Plane Block|PROCEDURE: Standard Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Extension Trial for Patients With Open-Angle Glaucoma Who Participated in the DF6-CL-20-01 Protocol.
Status: NOT_YET_RECRUITING
Conditions: Open Angle Glaucoma|Intraocular Pressure
Interventions: DEVICE: STREAMLINE® SURGICAL SYSTEM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First-in-human of Multiplle Doses of BB-1705 in Subjects With Locally Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: BB-1705
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cell Proliferation in Pulmonary Hypertension. FDG-PET Comparison Between Patients and Healthy Subjects
Status: COMPLETED
Conditions: Pulmonary Hypertension
Interventions: DRUG: fludeoxyglucose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nebivolol in the Supine Hypertension of Autonomic Failure
Status: COMPLETED
Conditions: Hypertension|Pure Autonomic Failure|Multiple System Atrophy
Interventions: DRUG: Placebo|DRUG: Nebivolol 5 mg|DRUG: metoprolol tartrate 50 mg|DRUG: Sildenafil25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Developing and Testing a Self-Compassion Tool Kit to Improve the Care of Individuals With Type 2 Diabetes
Status: RECRUITING
Conditions: Type 2 Diabetes|Diabetes Distress
Interventions: BEHAVIORAL: Self-Compassion Tool Kit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of Urate Elevation in Parkinson's Disease, Phase 3
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Inosine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Wearable Therapeutic Ultrasound Study for Knee Osteoarthritis
Status: TERMINATED
Conditions: Knee Osteoarthritis
Interventions: DEVICE: Ultrasonic Diathermy Device|DEVICE: Sham Ultrasonic Diathermy Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neural Correlates of Language Control in Bilinguals. Functional MRI and Stimulation Mapping Data in Awake Surgery.
Status: COMPLETED
Conditions: Bilingualism
Interventions: DEVICE: functional magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors
Status: RECRUITING
Conditions: Gastric Cancer|Gastro-esophageal Junction Cancer|Pancreatic Ductal Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: AZD5863
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety, Tolerability & Immunogenicity of CSL Limited's Influenza Virus Vaccine In a Paediatric Population
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine|BIOLOGICAL: Influenza Virus Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Multistrain Probiotic OMNi-BiOTiC® Active for Upper Respiratory Tract Infections in Older People
Status: COMPLETED
Conditions: Acute Upper Respiratory Tract Infection
Interventions: DIETARY_SUPPLEMENT: OMNi-BiOTiC® Active|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Rifaximin-treatment of Collagenous Colitis
Status: UNKNOWN
Conditions: Collagenous Colitis
Interventions: DRUG: Rifaximin 550 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Amelogenins and Systemic Inflammation After Periodontal Surgical Therapy
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: Periodontal surgery|PROCEDURE: EMD application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070)
Status: COMPLETED
Conditions: Hepatic Insufficiency
Interventions: DRUG: MK-0822
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome of Extremely Preterm Infants Who Received Systemic Postnatal Corticosteroid for Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Bronchopulmonary Dysplasia
Interventions: DRUG: Evaluation at 24 months corrected age: respiratory outcome, Neurodevelopmental outcome, Growth outcome
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Safety and Efficacy of Zishenqing in Subjects With Active Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Zishenqing|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Repeat Infusion of Autologous Bone Marrow Cells in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: PROCEDURE: Infusion of autologous bone marrow
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine and Kidney Transplantation
Status: NOT_YET_RECRUITING
Conditions: Renal Transplantation|Dexmedetomidine
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Cystocele|Uterine Prolapse
Interventions: DEVICE: Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination of Sintilimab and Stereotactic Body Radiotherapy in Hepatocellular Carcinoma (ISBRT01)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: stereotactic body radiotherapy|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerance Evaluation of a Bio-revitalizing Product Containing Hyaluronic Acid With High and Low Molecular Weight
Status: COMPLETED
Conditions: Malar and Sub-malar Volume Deficiency
Interventions: DEVICE: Profhilo
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EArly Discharge After Transradial Stenting of CoronarY Arteries in High-Risk Patients of Bleeding
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Bivalirudin|DRUG: Heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-rehabilitation in Patients Operated for Distal Radius Fracture
Status: COMPLETED
Conditions: Distal Radius Fracture
Interventions: OTHER: Telerehabilitation|OTHER: Face to face
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retrospective Study on Caplacizumab-treated Pediatric Patients With Immune-mediated Thrombocytopenic Purpura (iTTP)
Status: COMPLETED
Conditions: Immune-mediated Thrombocytopenic Purpura
Interventions: DRUG: Caplacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors
Status: RECRUITING
Conditions: Metastatic Esophageal|Gastric Cancer|Metastatic Head and Neck Carcinoma|Metastatic Hepatocellular Carcinoma|Metastatic HPV Related Solid Tumors|Metastatic Ovarian Carcinoma|Metastatic Soft Tissue Sarcoma|Metastatic Uveal Melanoma
Interventions: DRUG: LVGN3616 + LVGN6051 + Nab-Paclitaxel|DRUG: LVGN3616 + LVGN6051 + Bevacizumab + Cyclophosphamide|DRUG: LVGN3616 + LVGN6051 + LVGN7409 + Nab-Paclitaxel|DRUG: LVGN3616 + LVGN6051 + LVGN7409 + Bevacizumab + Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Superba Krill on Inflammation in Patients With Coronary Artery Disease
Status: COMPLETED
Conditions: Stable Atherosclerotic Coronary Disease
Interventions: DIETARY_SUPPLEMENT: Krill|DIETARY_SUPPLEMENT: Fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Real-Time Artificial Intelligence Assissted Colonoscopy to Identify and Classify Polyps
Status: COMPLETED
Conditions: Artificial Intelligence|Colonoscopy|Quality Control
Interventions: DIAGNOSTIC_TEST: DeFrame|DIAGNOSTIC_TEST: Classified DeFrame|DIAGNOSTIC_TEST: conventional colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Dry Needling When Applied to the Infraspinatus Muscle in People With Chronic Shoulder Pain
Status: COMPLETED
Conditions: Trigger Point Pain, Myofascial|Chronic Shoulder Pain
Interventions: OTHER: Dry needling|OTHER: Sham needling (SN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genomic Testing and Resulting Medical Decisions
Status: RECRUITING
Conditions: Cancer of Unknown Origin|Cancer Refractory|Cancer of Stomach|Cancer Head Neck|Cancer of Skin|Cancer, Lung|Cancer Colorectal|Cancer of Esophagus|Cancer, Bladder|Cancer, Uterus|Cancer Cervix|Cancer Liver|Cancer, Kidney|Cancer, Breast|Hematologic Neoplasms
Interventions: OTHER: Genomic testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating GAP-486 in Heart Rhythm
Status: TERMINATED
Conditions: Arrhythmia
Interventions: DRUG: GAP-486 (ZP-123)|DRUG: 0.9% Sodium Chloride, USP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: PTSD
Interventions: DRUG: Quetiapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Urocortins on Forearm Arterial Blood Flow in Healthy Volunteers (Protocol 2)
Status: COMPLETED
Conditions: Vascular Disease|Heart Disease
Interventions: DRUG: Urocortin 2, Urocortin 3|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacodynamic Differences Between Branded and Unbranded Remifentanil Molecules
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Remifentanyl, Ultiva®|DRUG: Remifentanil Laboratorios Chalver de Colombia S.A.|DRUG: Fada Remifentanilo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of the RNA MCTI CIMATEC HDT Vaccine
Status: UNKNOWN
Conditions: COVID-19|COVID-19 Vaccine
Interventions: BIOLOGICAL: RNA MCTI CIMATEC HDT 5µg|BIOLOGICAL: RNA MCTI CIMATEC HDT 10µg|BIOLOGICAL: Covishield® - AstraZeneca|BIOLOGICAL: Comirnaty® - Pfizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Standard Treatments of Very-early Stage Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Very-early Stage
Interventions: PROCEDURE: RFA|PROCEDURE: MWV|PROCEDURE: PEI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Shear Wave Ultrasound Elastography for Follow up After Anti-spastic Intervention Among Stroke Patients
Status: UNKNOWN
Conditions: Stroke|Spasticity, Muscle|Botulism|Ultrasound|Activity of Daily Living
Interventions: DRUG: Botulinum toxin injection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating the Efficacy and Safety of Cyclosporine Reduction in Kidney Transplant Recipients Receiving Sirolimus
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: DRUG: Sirolimus|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Zinc Supplementation to Enhance Botulinum Neurotoxin Response
Status: COMPLETED
Conditions: Dystonia, Focal
Interventions: DIETARY_SUPPLEMENT: Zinc Acetate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Suppression of Cytomegalovirus Retinitis Utilizing High Dose Intravenous Acyclovir and Oral Zidovudine in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Zidovudine|DRUG: Acyclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Efficacy of Dapagliflozin in Patients With Type 2 Diabetes Mellitus Aged 10-24 Years
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: Dapagliflozin|DRUG: Dapagliflozin placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduced Intensity Transplantation for Severe Sickle Cell Disease
Status: SUSPENDED
Conditions: Sickle Cell Disease
Interventions: DRUG: hydroxyurea, azathioprine, alemtuzumab, thioptepa, low dose total body irradiation and sirolimus|DRUG: hydroxyurea, azathioprine, alemtuzumab, thiotepa, plerixafor, low dose total body irradiation, cyclophosphamide and sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 6-Month Extension Study to Assess the Long-Term Safety of Engensis in Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Engensis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Depressed Mood and Anhedonia in Healthy Adults
Status: COMPLETED
Conditions: Anhedonia|Depressed Mood
Interventions: DIETARY_SUPPLEMENT: Nutraceutical|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Delivery Method and Risk for Urogenital Prolapse 15-20 Years Later
Status: COMPLETED
Conditions: Uterine Prolapse|Urinary Incontinence|Fecal Incontinence
Interventions: PROCEDURE: vaginal delivery|PROCEDURE: forceps extraction|PROCEDURE: vacuum extraction|PROCEDURE: cesarean section
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
Status: SUSPENDED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: BL22 immunotoxin|PROCEDURE: antibody-drug conjugate therapy|PROCEDURE: immunotoxin therapy|PROCEDURE: monoclonal antibody therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patients
Status: COMPLETED
Conditions: End Stage Kidney Disease
Interventions: OTHER: Structured Exercise program|DRUG: Cholecalciferol (25-Hydroxyvitamin D)|OTHER: Usual exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial
Status: COMPLETED
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: LPCN 1144
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nephrolithiasis and Bariatric Surgery
Status: COMPLETED
Conditions: Obesity|Nephrolithiasis
Interventions: OTHER: evaluation of kidney stone risk after bariatric surgery|OTHER: Evaluate risk of kidney stones after bariatric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Study Comparing Adapalene Gel 0.1% and to Differin Gel in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Adapalene Gel 0.1%|DRUG: Placebo Control|DRUG: Differin® Gel (Adapalene 0.1%, Galderma)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bortezomib and Carboplatin in Treating Patients With Metastatic Pancreatic Cancer
Status: TERMINATED
Conditions: Acinar Cell Adenocarcinoma of the Pancreas|Duct Cell Adenocarcinoma of the Pancreas|Stage IV Pancreatic Cancer
Interventions: DRUG: bortezomib|DRUG: carboplatin|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of iRoot SP as Root Canal Sealer: A Clinical Study
Status: COMPLETED
Conditions: Irreversible Pulpitis|Apical Periodontitis
Interventions: PROCEDURE: Root canal sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GORE® Embolic Filter in Carotid Stenting for High Risk Surgical Subjects (EMBOLDEN)
Status: COMPLETED
Conditions: Carotid Artery Stenosis
Interventions: DEVICE: GORE® Embolic Filter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apixaban After Anticoagulation-associated Intracerebral Haemorrhage in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Cerebral Hemorrhage|Atrial Fibrillation
Interventions: DRUG: Apixaban|DRUG: Aspirin|DRUG: Carbasalate calcium|DRUG: Clopidogrel|DRUG: Dipyridamole|OTHER: No antithrombotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgical Resection With or Without Axillary Lymph Node Dissection in Treating Women With Node-Negative Breast Cancer and Sentinel Lymph Node Micrometastases
Status: COMPLETED
Conditions: Breast Cancer
Interventions: PROCEDURE: Axillary lymph node dissection|PROCEDURE: No axillary lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Postoperative Pain With Resin Based Sealer vs Zinc Oxide Eugenol Based Sealer After Single Visit Endodontic
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: PROCEDURE: Zinc oxide eugeonal based sealer|PROCEDURE: Resin Based Sealer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Asynchronous and Synchronous Telepsychiatry for Skilled Nursing Facilities
Status: COMPLETED
Conditions: Dementia|Depression|Mood Disorder|Anxiety Disorder|Substance Use Disorder
Interventions: BEHAVIORAL: Psychiatric Consultation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cold and Isometric Strength
Status: COMPLETED
Conditions: Muscle Strength
Interventions: PROCEDURE: Brief Cooling|PROCEDURE: Prolonged Cold|PROCEDURE: Sham Ice Bag
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Role of High Density Surface ECG in the Diagnosis of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Status: COMPLETED
Conditions: Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions: DEVICE: 80 lead ECG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Immuno-PRISM (PRecision Intervention Smoldering Myeloma)
Status: RECRUITING
Conditions: High-risk Smoldering Multiple Myeloma|Smoldering Multiple Myeloma|Multiple Myeloma
Interventions: DRUG: Teclistamab|DRUG: Lenalidomide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Age and Inspiratory Resistance on the Inspiratory Gas Levels While Wearing Air Purifying Respirator "
Status: UNKNOWN
Conditions: Aging
Interventions: DEVICE: "Yaalom Katom"
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Treatment Effect Between Dexlansoprazole and Double-dose Lansoprazole in Obesity Patients With Reflux Esophagitis
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Dexlansoprazole|DRUG: Lansoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dyadic Sleep Study
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Cancer
Interventions: BEHAVIORAL: My Sleep Our Sleep (MSOS) Program|BEHAVIORAL: Brief Behavioral Treatment for Insomnia (BBTI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization
Status: TERMINATED
Conditions: Antibody Mediated Rejection
Interventions: DRUG: Eculizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Occlusion Balloons of Both Internal Iliac Arteries in Caesarean Hysterectomy for PASD
Status: COMPLETED
Conditions: Hemorrhage|Placenta Accreta Spectrum|Cesarean Section Complications
Interventions: PROCEDURE: caesarean hysterectomy with prior placement of prophylactic occlusion balloons of both internal iliac arteries|PROCEDURE: caesarean hysterectomy without prior placement of prophylactic occlusion balloons of both internal iliac arteries
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound vs. Predetermined Distance Techniques for Paravertebral Nerve Block in Patients Having Breast Surgery
Status: UNKNOWN
Conditions: Mastectomy|Breast Neoplasms
Interventions: PROCEDURE: ultrasound|PROCEDURE: predetermined distance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome
Status: COMPLETED
Conditions: Depression|Acute Coronary Syndrome
Interventions: DRUG: Melatonin (N-acetyl-5-methoxytryptamine)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A New Dual Task Test Method for Football Players
Status: ENROLLING_BY_INVITATION
Conditions: Sports Physical Therapy|Multi-Tasking Behavior|ACL Injury|Kinesiophobia
Interventions: DIAGNOSTIC_TEST: A new dual-task measurement method with images|DIAGNOSTIC_TEST: A new dual-task measurement method with cards
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides
Status: COMPLETED
Conditions: Facial Rhytides|Glabellar Rhytides
Interventions: BIOLOGICAL: OnabotulinumtoxinA|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral 6R-BH4 for the Treatment of Isolated Systolic Hypertension and Endothelial Dysfunction
Status: TERMINATED
Conditions: Isolated Systolic Hypertension|Endothelial Dysfunction
Interventions: DRUG: 6R-BH4|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Surgical Approach Affect on Post-operative Analgesic Requirement Following Laparoscopic Nephrectomy
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Transperitoneal laparoscopic nephrectomy|DRUG: Retroperitoneal laparoscopic nephrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic and Lymphoid Cell Neoplasm|Malignant Solid Neoplasm|Prediabetes
Interventions: OTHER: Exercise Intervention|DIETARY_SUPPLEMENT: Nicotinamide Riboside
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Induced Moderate HYPOthermia on Mortality in Cardiogenic Shock Patients Rescued by Veno-arterial ExtraCorporeal Membrane Oxygenation (ECMO)
Status: COMPLETED
Conditions: Cardiogenic Shock
Interventions: OTHER: moderate hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amoxicillin and Metronidazole During Periodontal Treatment
Status: UNKNOWN
Conditions: Chronic Periodontitis
Interventions: PROCEDURE: Scaling and root planing|DRUG: Metronidazole active phase|DRUG: Metronidazole healing phase|DRUG: Amoxicillin active phase|DRUG: Amoxicillin healing phase|DRUG: Placebos active phase|DRUG: Placebos healing phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Cisatracurium on Succinylcholine-induced Fasciculations and Myalgia
Status: COMPLETED
Conditions: Fasciculation
Interventions: DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Levitra (Vardenafil, BAY38-9456) Partner Satisfaction Study II
Status: COMPLETED
Conditions: Sexual Dysfunction|Male Erectile Dysfunction
Interventions: DRUG: Levitra (Vardenafil, BAY38-9456)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Outcome Effect of Shoe Lift for Individuals With Low Back Pain and Pronated Foot Due to Anatomical Leg Length Discrepancy
Status: COMPLETED
Conditions: Low Back Pain|Flatfoot|Leg Length Inequality
Interventions: OTHER: shoe lift
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study on the Effect of Tizanidine on the Function and Pain of Patients After Shoulder Arthroscopy
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Tears
Interventions: DRUG: Celecoxib+Buprenorphine Transdermal Patch|DRUG: Celecoxib+Buprenorphine Transdermal Patch+Tizanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In-vivo Extraction of Pb, Cd and TSNA From Swedish Snus
Status: COMPLETED
Conditions: Smoking Cessation|Smokeless Tobacco|Harm Reduction
Interventions: PROCEDURE: Buccal administration of nicotine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Point of Care Ultrasound For The Diagnosis Of Deep Venous Thrombosis And Its Effect On Length Of Hospital Stay
Status: COMPLETED
Conditions: Deep Venous Thromboses|Deep Venous Thrombosis of Left Leg|Deep Venous Thrombosis of Right Leg|Deep Venous Thrombosis Proximal
Interventions: DIAGNOSTIC_TEST: Point Of Care Ultrasound (PODUS)|DIAGNOSTIC_TEST: Echo Doppler Ultrasound (EDUS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of California Strawberries on Parameters of Cardiovascular Health
Status: COMPLETED
Conditions: Childhood Obesity|Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: flavonoid-rich freeze-dried strawberry powder|DIETARY_SUPPLEMENT: macronutrient-matched control powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: EPISODE-PS-COVID: hEad Pulse for Ischemic StrOke DEtection Prehospital Study During the COVID-19 Pandemic ( EPISODEPSCOVID )
Status: COMPLETED
Conditions: Stroke, Acute|COVID-19
Interventions: DEVICE: MindRhythm Harmony
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Vonoprazan From Topoprazan 20 mg Tablets (Hikma Pharma, Egypt) Versus Takecab 20 mg Tablets (Takeda Pharmaceutical Co. Ltd., Japan)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Topoprazan|DRUG: Takecab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)
Status: RECRUITING
Conditions: Stroke|Vascular Accident|Intracranial Hemorrhages|Intracerebral Hemorrhage|Hemorrhagic Stroke|Stroke, Acute
Interventions: DRUG: Propranolol Hydrochloride|OTHER: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT