pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluation of Performance Characteristics and Applicability in Oncology of Devices Customized Medical Devices Made by 3D Printing
Status: RECRUITING
Conditions: Sarcoma|Intracranial Neoplasm|Pelvic Bone Neoplasm
Interventions: DEVICE: 3D printer applications
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Weighted Blankets for Sleep Disturbance Among Children With ADHD
Status: RECRUITING
Conditions: Attention-deficit Hyperactivity|Attention Deficit Hyperactivity Disorder|Neurodevelopmental Disorders|Sleep Disturbance|Attention Deficit Disorder|Hyperkinetic Conduct Disorder|Attention-Deficit Hyperactivity Disorder, Unspecified Type
Interventions: DEVICE: Weighted blanket|DEVICE: Non-weighted blanket
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Evaluating Autologous Bone Marrow Derived Mesenchymal Stromal for Crohn's Disease.
Status: COMPLETED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: autologous mesenchymal stromal cell
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A High-Resolution Magnetic Resonance Imaging Study to Evaluate the Effect of Rosuvastatin on Carotid Atherosclerotic Plaques
Status: UNKNOWN
Conditions: Arteriosclerosis|Diabetes Mellitus|Lipid Disorder
Interventions: DRUG: Rosuvastatin 5mg|DRUG: Rosuvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sevelamer and Secondary Hyperparathyroidism in Chronic Kidney Disease
Status: COMPLETED
Conditions: Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: sevelamer carbonate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Efficacy of Botulinum Toxin Injection in Reducing Limb Pain in Patients With Complex Regional Pain Syndrome"
Status: UNKNOWN
Conditions: Complex Regional Pain Syndrome
Interventions: DRUG: Botox + Lidocaine|DRUG: Lidocaine alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Left Ventricular Fibrosis in Chronic Kidney Disease
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Cardio-Renal Syndrome|Myocardial Fibrosis|Uraemic Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: cardiac magnetic resonance scan|DIAGNOSTIC_TEST: Cardiopulmonary exercise test with stress echocardiogram|DIAGNOSTIC_TEST: 24-hour ECG holter monitor|DIAGNOSTIC_TEST: 12-lead ECG|DIAGNOSTIC_TEST: Cardiopulmonary exercise test|BIOLOGICAL: Blood test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study)
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Simulect®|DRUG: Neoral®|DRUG: Certican®|DRUG: Myfortic®|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers
Status: TERMINATED
Conditions: Intermittent Claudication
Interventions: DRUG: Cilostazol 100 mg|DRUG: PMR 135 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations
Status: NOT_YET_RECRUITING
Conditions: Ocular Redness|Eye Irritation
Interventions: DRUG: FID 123320 Ophthalmic Solution|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of Fractionated Stereotactic Radiotherapy for Medically Inoperable NSCLC or Metastatic Lung Tumours
Status: COMPLETED
Conditions: Lung Neoplasms|Lung Cancer
Interventions: PROCEDURE: Fractionated Stereotactic Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Pharmacodynamics of B12019 and Neulasta® in Healthy Subjects
Status: COMPLETED
Conditions: Clinical Pharmacology
Interventions: BIOLOGICAL: B12019 and Neulasta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD
Status: ACTIVE_NOT_RECRUITING
Conditions: Neuromyelitis Optica|Neuromyelitis Optica Spectrum Disorder
Interventions: BIOLOGICAL: Ravulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Antiviral Therapy for HBeAg-positive Chronic Hepatitis B Patients Aged 1-16 Years
Status: UNKNOWN
Conditions: HBeAg Positive Chronic Hepatitis B
Interventions: DRUG: NAs+IFN-α
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Finding Study on BI54903 (Inhaled Corticosteroid) Administered Twice Daily Via Respimat® Inhaler in Asthmatic Patients Inadequately Controlled on Short-acting-beta-agonist (SABA) Therapy
Status: TERMINATED
Conditions: Asthma
Interventions: DRUG: Fluticasone propionate|DRUG: Placebo|DRUG: BI 54903
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Ankle Spine Syndrome "RAFFET Syndrome II
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Ankle Injuries|Chronic Low-back Pain|Lumbar Disc Herniation|Calf Muscle Weakness
Interventions: OTHER: calf muscle strengthening and streching
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alisertib (MLN8237) or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Relapsed Peripheral T-Cell Lymphoma|Refractory Peripheral T-Cell Lymphoma
Interventions: DRUG: Alisertib|DRUG: Pralatrexate|DRUG: Gemcitabine|DRUG: Romidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CINJALL: Treatment for Children With Acute Lymphocytic Leukemia
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia
Interventions: DRUG: aminopterin|DRUG: L-asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunomycin|DRUG: dexamethasone|DRUG: 6-mercaptopurine|DRUG: methotrexate|DRUG: 6-thioguanine|DRUG: vincristine|DRUG: Triple Intrathecal Therapy (MTX, Cytarabine, Hydrocortisone)|DRUG: Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Polylactide-Caprolactone-Trimethylenecarbonate Copolymer for Post-Operative Adhesion Prophylaxis
Status: COMPLETED
Conditions: Adhesions
Interventions: DEVICE: polylactide-caprolactone-trimethylenecarbonate copolymer|DEVICE: Icodextrin 4%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin glargine|DRUG: insulin aspart
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Controlling Malodour In Fungating Wounds Using A Cinnamon-Based Dressing: Observational Study
Status: NOT_YET_RECRUITING
Conditions: Wound
Interventions: DEVICE: Cinesteam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies
Status: RECRUITING
Conditions: CLL/SLL|NHL|Mantle Cell Lymphoma|Follicular Lymphoma|Large B-cell Lymphoma|Indolent B-Cell Non-Hodgkin Lymphoma|Diffuse Large B Cell Lymphoma
Interventions: DRUG: SYNCAR-001|DRUG: STK-009|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effect of Whole-wheat Sourdough Bread Compared to White Bread on Healthy Individuals
Status: COMPLETED
Conditions: Dietary Modification|Bread|Gastrointestinal Microbiome|Hematologic Tests|Body Weight Changes
Interventions: OTHER: Consumption of sourdough bread|OTHER: Consumption of white bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 Study
Status: COMPLETED
Conditions: Glaucoma and Ocular Hypertension
Interventions: DRUG: DE-117 Ophthalmic Solution|DRUG: Timolol Maleate Ophthalmic Solution 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors
Status: RECRUITING
Conditions: Lung Cancer Squamous Cell|Solid Tumors|Head & Neck Cancer|Pancreatic Cancer
Interventions: DRUG: Palbociclib|DRUG: Gedatolisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigating Efficacy and Safety of Once-weekly NNC0195-0092 (Somapacitan) Treatment Compared to Daily Growth Hormone Treatment (Norditropin® FlexPro®) in Growth Hormone Treatment naïve Pre-pubertal Children With Growth Hormone Deficiency
Status: RECRUITING
Conditions: Growth Hormone Disorder|Growth Hormone Deficiency in Children
Interventions: DRUG: somapacitan|DRUG: Norditropin® FlexPro® pen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Study of Steroid Injection and Physical Therapy for Acute Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow|Epicondylitis, Lateral Humeral
Interventions: DRUG: triamcinolone|DRUG: Placebo|DRUG: Lidocaine|OTHER: Physiotherapy|DRUG: Naproxen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Pilot Study of Cladribine (2-Chlorodeoxyadenosine; 2-CdA) for Early Stage Primary Sclerosing Cholangitis
Status: COMPLETED
Conditions: Cholangitis, Sclerosing
Interventions: DRUG: cladribine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Impact of Rifabutin on the Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor
Status: COMPLETED
Conditions: Drug Drug Interaction
Interventions: DRUG: Trikafta [orange tablet containing ELX 100mg, TEZ 50mg, and IVA 75mg]|DRUG: Rifabutin 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Helping Youth on the Path to Employment
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Impairment|Educational Problems
Interventions: BEHAVIORAL: Weekly Meetings with a Supported Employment/Supported Education Specialist|BEHAVIORAL: Focused Skill and Strategy Training (FSST)|BEHAVIORAL: Enhanced Services as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: DMEK Endothelial Keratoplasty in Patients With a History of Anterior or Posterior Segment Surgery
Status: RECRUITING
Conditions: Patients Undergoing DMEK With a History of Anterior or Posterior Segment Surgery
Interventions: PROCEDURE: Descemet Membrane Endothelial Keratoplasty
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biology, Identity & Opportunity Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Stress, Psychological|Stress, Emotional|Stress, Physiological
Interventions: BEHAVIORAL: Ethnic and Racial Identity Promotion|BEHAVIORAL: Academic Skills Promotion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS
Status: COMPLETED
Conditions: Graft vs Host Disease|Myelodysplastic Syndromes|Leukemia|Leukemia, Myeloid|Leukemia, Myelomonocytic, Chronic|Leukemia, Lymphocytic|Lymphoma|Lymphoma, Mantle-cell|Lymphoma, Non-Hodgkin|Hodgkin Disease
Interventions: DRUG: RFT5-SMPT-dgA|DRUG: Isolex system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetic Study of Dexmedetomidine in Pediatrics Ages ≥28 Weeks to ≤44 Weeks Gestational Age
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Midazolam|DRUG: Fentanyl/Morphine|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Dupilumab to Demonstrate Efficacy in Subjects With Nummular Eczema
Status: RECRUITING
Conditions: Nummular Eczema
Interventions: DRUG: Experimental: Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reactogenicity and Immunogenicity of Vaginal CNgp140
Status: TERMINATED
Conditions: HIV Infections|Acquired Immune Deficiency Syndrome
Interventions: BIOLOGICAL: HIV glycoprotein CN54gp140 (vaccine)|BIOLOGICAL: Carbopol 974
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Needle Size in Diagnostic Yield of EBUS-TBNA in Sarcoidosis and Lymphoma
Status: RECRUITING
Conditions: Sarcoidosis|Lymphoma|Adenopathy Hilar
Interventions: DEVICE: ViziShot FLEX 19G needle|DEVICE: Vizishot 22G needle (standard)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Pembrolizumab and External Beam Radiation Therapy in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Mediastinal (Thymic) Large B-Cell Lymphoma|Recurrent Aggressive Non-Hodgkin Lymphoma|Recurrent Mature T- Cell and NK-Cell Non-Hodgkin Lymphoma|Recurrent Non-Hodgkin Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Refractory Aggressive Non-Hodgkin Lymphoma|Refractory Non-Hodgkin Lymphoma|Refractory T-Cell Non-Hodgkin Lymphoma|Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma|Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions: RADIATION: External Beam Radiation Therapy|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAKE Steps: Motivational Interviewing to Prevent STIs
Status: COMPLETED
Conditions: Self Efficacy|HIV Prevention|STI Prevention
Interventions: BEHAVIORAL: Treat Act Know Engage (T.A.K.E.) Steps|BEHAVIORAL: Standard or Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Lung Recruitment Maneuver on Postoperative Atelectasis in Children
Status: COMPLETED
Conditions: Atelectasis
Interventions: PROCEDURE: recruitment maneuver|PROCEDURE: ultrasonography-guided recruitment maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation
Status: COMPLETED
Conditions: Dental Implant|Immediate Dental Implant|Soft Tissue Augmentation
Interventions: DEVICE: Immediate implant|BIOLOGICAL: SCTG|BIOLOGICAL: ADM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM)
Status: UNKNOWN
Conditions: Incisional Hernia
Interventions: DEVICE: Biological swine dermis not cross-linked prosthesis positioning in incisional hernia prevention|PROCEDURE: Direct suture of the anterior abdominal wall fascia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Flow Nasal Cannula During Pulmonary Rehabilitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: High Flow Nasal Cannula|DEVICE: Nasal Cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Reducing Pain Intensity During Spinal Needle Insertion: Valsalva Maneuver vs. Control Technique
Status: COMPLETED
Conditions: Undefined
Interventions: BEHAVIORAL: Valsalva Maneuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase I/II Safety and Immunogenicity of Pandemic Live Attenuated Influenza Vaccine (PLAIV) Candidate Strain A/17/CA/2009/38 (H1N1) in Healthy Thais
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: Vaccine A/17/CA/2009/38 (H1N1)|OTHER: Placebo:Stabilizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Single Dose Phase I Exploratory Study in Healthy Volunteers With GSK2894512 Cream
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Combination therapy GSK2894512 Cream A + GSK2894512 Cream B|DRUG: Combination therapy Vehicle Cream A + Vehicle Cream B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Platelet Administration To Patients With Traumatic Brain Injury Who Were Treated With Aspirin
Status: UNKNOWN
Conditions: Aspirin Treatment|Traumatic Intracranial Bleed|Hemorrhage Growth|Neurological Outcome
Interventions: DRUG: platelets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn How Safe the Study Treatment BAY94-9027 is and How it Affects the Body in Previously Treated Children Aged 7 to Less Than 12 Years With Severe Hemophilia A, a Genetic Bleeding Disorder That is Caused by the Lack of a Protein Called Clotting Factor 8 (FVIII) in the Blood
Status: ACTIVE_NOT_RECRUITING
Conditions: Treatment of Bleeding|Prophylaxis of Bleeding|Hemophilia A|Children
Interventions: BIOLOGICAL: Damoctocog alfa pegol (Jivi, BAY94-9027)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy
Status: COMPLETED
Conditions: Pain|Colorectal Adenomas|Colorectal Cancer
Interventions: OTHER: Air Insufflation method.|OTHER: CO2 insufflation|OTHER: Water Immersion/CO2|OTHER: Water Exchange/CO2|OTHER: Water Immersion/AI|OTHER: Water Exchange/AI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: GLPG1690|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas
Status: COMPLETED
Conditions: Pilomyxoid Astrocytoma|Pilocytic Astrocytoma|Glioma, Astrocytic|Optic Nerve Glioma|Pleomorphic Xanthoastrocytoma|Glioblastoma Multiforme|Anaplastic Astrocytoma|Gliosarcoma|Diffuse Intrinsic Pontine Glioma|DIPG|Low-grade Glioma|Brainstem Glioma
Interventions: DRUG: Mebendazole|DRUG: Vincristine|DRUG: Carboplatin|DRUG: Temozolomide|DRUG: Bevacizumab|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Continuation Trial for Subjects With Systemic Lupus Erythematosus That Have Completed Protocol LBSL02
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Belimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Functional Outcomes of Flexor Tendon Repair Under WALANT and Brachial Plexus Block
Status: RECRUITING
Conditions: Flexor Tendon Rupture
Interventions: PROCEDURE: FLEXOR TENDON REPAIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tele-Health Education Provided in the Postpartum Period in the Covid 19 Pandemic
Status: UNKNOWN
Conditions: Postpartum Depression|Anxiety State
Interventions: BEHAVIORAL: Experimental
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Kinesio Taping and Sham Taping in Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: Kinesio taping|PROCEDURE: Sham taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verify the Safety and Effectiveness of the Cerclage Pessary in Prevention and Treatment of High-risk Preterm Pregnancy
Status: NOT_YET_RECRUITING
Conditions: High Risk Pregnancy
Interventions: DRUG: Progesterone|DEVICE: pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea in Elective Orthopaedic Surgery
Status: WITHDRAWN
Conditions: Sleep Apnea, Obstructive|Total Knee Arthroplasty|Total Hip Arthroplasty
Interventions: OTHER: Evaluation by Sleep Medicine Specialists
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ATG Individualized Dosing Model in URD-PBSCT.
Status: RECRUITING
Conditions: Cytomegalovirus Infections|Infection Reactivation|Stem Cell Transplant Complications
Interventions: DRUG: individualized ATG dosing strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioequivalence of XC8 10 mg and 40 mg Tablets in Fasted Volunteers
Status: COMPLETED
Conditions: Influenza|Respiratory Viral Infection
Interventions: DRUG: XC8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study of Perjeta (Pertuzumab) in Combination With Herceptin (Trastuzumab) in Participants With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential Added Value of Impulse Oscillometry in Asthma Monitoring
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: OTHER: Full lung function|OTHER: Multiple breath nitrogen washout|OTHER: Impulse oscillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Mobilization for Critical Patients on Invasive Mechanical Ventilation in the Intensive Care Unit
Status: COMPLETED
Conditions: Critical Illness
Interventions: DEVICE: Cycle Ergometer|OTHER: Conventional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Status: COMPLETED
Conditions: Developmental Disability|Intellectual Disability|Dental Anxiety
Interventions: BEHAVIORAL: Sensory Adapted Dental Environment (SADE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Famitinib Plus Docetaxel in Patients With Advanced Non-squamous and Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer (NSCLC)
Interventions: DRUG: famitinib L + docetaxel|DRUG: famitinib M + docetaxel|DRUG: famitinib H + docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Accompanying Support in the Active Phase on Labor Pain, Duration and Satisfaction
Status: COMPLETED
Conditions: Continuous Birth Support
Interventions: PROCEDURE: uninterrupted accompanying support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Observational Study to Evaluate BD PureHub™ Disinfecting Cap Use on Needle-Free Connectors
Status: COMPLETED
Conditions: Catheter Related Complication|Vascular Access Site Management|Disinfecting Cap
Interventions: DEVICE: BD PureHub™ Disinfecting Cap Placements: Attachments/removals
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Sitagliptin Therapy to Improve Outcomes After Islet Autotransplant
Status: COMPLETED
Conditions: Pancreatitis|Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Role of B Mode and Color Doppler Sonography in Differentiation Between Pleural Neoplasm and Inflammatory Pleural Thickening in Correlation With CT Findings
Status: RECRUITING
Conditions: Pleural Thickening
Interventions: DIAGNOSTIC_TEST: biopsy under sonographic gidance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vascular Dysfunction in Human Obesity Hypertension
Status: TERMINATED
Conditions: Obesity|Prehypertension|Hypertension
Interventions: DRUG: Clonidine|DRUG: Hydrochlorothiazide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity Study of Inactivated Nasal Influenza Vaccine NB-1008
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: BIOLOGICAL: NB-1008|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Brimonidine Tartrate/Timolol Fixed Combination in Patients With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension
Interventions: DRUG: brimonidine tartrate/timolol fixed combination ophthalmic solution|DRUG: brimonidine tartrate ophthalmic solution|DRUG: timolol ophthalmic solution|OTHER: fixed combination vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Antiviral Activity of TMC310911 When Administered With Ritonavir in Treatment-Naive Human Immunodeficiency Virus - Type 1 (HIV-1) Infected Patients
Status: COMPLETED
Conditions: Human Immunodeficiency Virus Type 1
Interventions: DRUG: TMC310911 75 mg twice daily|DRUG: TMC310911 150 mg twice daily|DRUG: TMC310911 300 mg twice daily|DRUG: TMC310911 300 mg once daily|DRUG: Ritonavir 100 mg twice daily|DRUG: Ritonavir 100 mg once daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Phantom Limb and Stump Pain Using Ambulatory Continuous Peripheral Nerve Blocks: A Pilot Study
Status: TERMINATED
Conditions: Amputation|Phantom Limb Pain|Stump Pain
Interventions: PROCEDURE: perineural ropivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality Training for Walking Improvement in the Elderly
Status: RECRUITING
Conditions: Gait, Unsteady
Interventions: DEVICE: The C-Mill virtual reality treadmill|OTHER: Conventional Physical Therapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of Orfadin 20 mg Compared to Orfadin 10 mg Capsules.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Nitisinone 20 mg|DRUG: Nitisinone 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intermittent Oro-Esophageal Tube Feeding vs. Nasogastric Tube Feeding in Infants With Pierre Robin Syndrome
Status: TERMINATED
Conditions: Pierre-Robin Syndrome|Dysphagia
Interventions: BEHAVIORAL: systematic therapy|DEVICE: PNG|DEVICE: IOE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia
Status: UNKNOWN
Conditions: Polycythemia Vera|Essential Thrombocythemia
Interventions: DRUG: HDAC inhibitor (MK-0683)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Anterior Quadratus Lumborum Block
Status: COMPLETED
Conditions: Postoperative Pain|Ultrasound
Interventions: DRUG: Morphine Sulfate|PROCEDURE: Group P|PROCEDURE: Group A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Nutritional Intervention on Health Parameters in Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2|Diabetes Mellitus Type 2 in Obese|Diabetes|Diabetes Mellitus Non-insulin-dependent|Hypertension|Type 2 Diabetes Mellitus
Interventions: BEHAVIORAL: Nutritional Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simulation-based Ultrasound Training to Improve Patient Comfort and Decrease the Need for Re-examination. A Randomized Trial.
Status: COMPLETED
Conditions: Conditions Related to Early Pregnancy
Interventions: OTHER: Simulation-based training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epoetin Alfa (EPO) in Subjects With Chronic Kidney Disease (CKD)
Status: TERMINATED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Epoetin alfa DT|DRUG: Epoetin alfa RB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Measurement of Total Retinal Blood Flow and Oxygen Extraction in Patients With Diabetes and Healthy Subjects
Status: UNKNOWN
Conditions: Retinal Blood Flow
Interventions: DEVICE: Fourier Domain Color Doppler Optical Coherence Tomography (FDOCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Repeat Sexually Transmitted Infection (STI) Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk
Status: COMPLETED
Conditions: Sexually Transmitted Infection|HIV
Interventions: BEHAVIORAL: Tailored Socio-Contextual Intervention|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
Status: RECRUITING
Conditions: Urinary Tract Infections
Interventions: DRUG: Gentamicin|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Optimization, Adjustment and Measurement for Deep Brain Stimulation
Status: ACTIVE_NOT_RECRUITING
Conditions: Parkinson Disease
Interventions: DEVICE: Abbott Infinity DBS systems with the NeuroSphere Virtual Clinic feature|DEVICE: Abbott Infinity DBS systems with the NeuroSphere Virtual Clinic feature (virtual clinic and in-clinic sessions)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance of Healthy Term Infants Fed Infant Formulas
Status: COMPLETED
Conditions: Infant, Newborn
Interventions: OTHER: milk protein formulas, varying carbohydrate/protein sources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunobridging Study of 9- Valent Human Papillomavirus (9vHPV) Vaccine (V503) in Chinese Females 9 to 45 Years of Age (V503-024)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: V503
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Decitabine Plus Penpulimab as Second-line Therapy for Advanced ESCC Treated With PD-1 Blockade
Status: NOT_YET_RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Decitabine plus Penpulimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Acceptability Study of Unflavored Asenapine Versus Raspberry Flavored Asenapine in Stable Patients With a Psychotic Disorder (P07010)(COMPLETED)
Status: COMPLETED
Conditions: Psychosis
Interventions: DRUG: Asenapine WHITE raspberry flavor (Treatment A)|DRUG: Asenapine RED raspberry flavor (Treatment B)|DRUG: Asenapine WHITE UNFLAVORED (Treatment C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children
Status: UNKNOWN
Conditions: Pneumonia|Meningitis|Bacteraemia|Sepsis|Otitis Media
Interventions: BIOLOGICAL: Prevenar 13 and Synflorix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Acute Effects of Guided Imagery and tDCS on Pain Levels in Women With Chronic Pelvic Pain
Status: WITHDRAWN
Conditions: Pelvic Pain|Chronic Pain
Interventions: DEVICE: Active tDCS with guided imagery|DEVICE: Active tDCS alone (no guided imagery)|DEVICE: Sham tDCS with guided imagery|DEVICE: Sham tDCS alone (no guided imagery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Steel and Bioabsorbable Screw Fixation of Lisfranc Foot Injuries
Status: COMPLETED
Conditions: Joint Instability
Interventions: DEVICE: Linvatec 4.5 mm Smart Screw|DEVICE: Synthes 4.0 mm steel screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Cancer Prevention and Control Pathways-Native Health Initiative
Status: COMPLETED
Conditions: Cancer, Breast|Cancer, Colon|Cancer, Cervix
Interventions: BEHAVIORAL: Breast, Colorectal, and Cervical Cancer Screening Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: The Effectiveness of YAG Iridotomy in Preventing Peripheral Anterior Synechia After CLASS in Primary Open Angle Glaucoma
Status: UNKNOWN
Conditions: Glaucoma, Open-angle
Interventions: DEVICE: YAG iridotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ELECtric Tibial Nerve Stimulation to Reduce Incontinence in Care Homes
Status: UNKNOWN
Conditions: Urinary Incontinence
Interventions: DEVICE: Transcutaneous posterior tibial nerve stimulation|DEVICE: Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First in Human Study of an Anti-IFN Gamma Monoclonal Antibody in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: NI-0501|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Vopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Vopratelimab|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Duloxetine in Patients Hospitalized for Severe Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Duloxetine hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trifluridine/Tipiracil in Combination With Irinotecan as a Second Line Therapy in Patients With Cholangiocarcinoma
Status: COMPLETED
Conditions: Cholangiocarcinoma
Interventions: COMBINATION_PRODUCT: Combination of Lonsurf® and Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate Dosage, Efficacy, and Safety of Perampanel Given as Monotherapy in Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Partial-Onset Seizures|Primary Generalized Tonic-Clonic Seizures
Interventions: OTHER: No treatment (intervention) was administered
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Impact of an Education Program for Parents of Children With Cerebral Palsy
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: OTHER: Education + Conventional PhysicalTherapy|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Evaluation of Sustained Acoustic Medicine Device on Circulation
Status: RECRUITING
Conditions: Measurement of Circulation on Anatomical Locations of the Body
Interventions: DEVICE: Sustained Acoustic Medicine|DEVICE: Sustained Acoustic Medicine|DEVICE: Sustained Acoustic Medicine|DEVICE: Sustained Acoustic Medicine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
Status: RECRUITING
Conditions: Thyroid Cancer|Thyroid Carcinoma|Metastatic Thyroid Cancer|Follicular Thyroid Cancer|Unresectable Thyroid Gland Carcinoma|Papillary Thyroid Cancer
Interventions: DRUG: Selpercatinib|DRUG: Sodium Iodine I-131|DRUG: rhTSH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Mifepristone|DRUG: Placebo - Cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Benefits and Costs of Integrating Sexual-Reproductive Health and HIV Services in Kenya and Swaziland
Status: COMPLETED
Conditions: Pregnancy|HIV
Interventions: PROCEDURE: Integrated FP/PNC service delivery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomised Controlled Trial of Structured Personal Care of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus|Quality of Health Care|Health Services Research
Interventions: BEHAVIORAL: Structured personal care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Arrhythmia
Interventions: OTHER: Measure of ODI and heart rhythm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Low Energy Surface Waves for Neurogenic Bladder Patients With Indwelling Catheters
Status: TERMINATED
Conditions: Neurogenic Bladder|Urinary Tract Infections
Interventions: DEVICE: Uroshield|DEVICE: Sham Uroshield
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation the Effect of Acetyl-L-carnitine in Patients With Mild Cognitive Impairment Accompanied With Chronic Cerebrovascular Disease
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Acetyl-L-carnitine hydrochloride 500mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma
Status: COMPLETED
Conditions: Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Recurrent Adult Brain Neoplasm
Interventions: DRUG: Cediranib Maleate|DRUG: Cilengitide|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib or Cediranib for Alveolar Soft Part Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Sarcoma, Alveolar Soft Part
Interventions: DRUG: Cediranib|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocular Point of Care Ultrasound (POCUS) to Detect Optic Disc Swelling in Comparison to Ophthalmologic Examination
Status: UNKNOWN
Conditions: Papilledema Associated With Increased Intracranial Pressure
Interventions: DEVICE: Point of care ocular ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Carboplatin, Docetaxel, and Radiation Therapy in Treating Patients With Stage III/IV, or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: carboplatin|DRUG: docetaxel|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Steroid Treatment for Sickle Cell Pain Crisis
Status: TERMINATED
Conditions: Sickle Cell Disease|Vaso-occlusive Crisis
Interventions: DRUG: Steroid arm|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benralizumab in the Treatment of Patients With Severe Asthma With ABPA
Status: WITHDRAWN
Conditions: ABPA|Severe Asthma|Allergic Bronchopulmonary Aspergillosis
Interventions: DRUG: Fasenra, 30 Mg/mL Subcutaneous Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT