pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: FSH Treatment for Non-obstructive Azoospermic Patients
Status: UNKNOWN
Conditions: Azoospermia
Interventions: DRUG: Urofollitropin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Fluticasone /Formoterol Breath Actuated Inhaler (BAI) and Ultibro in Subjects With Fixed Airflow Obstruction and Elevated Eosinophils
Status: TERMINATED
Conditions: ACOS (Fixed Airflow Obstruction and Elevated Eosinophils)
Interventions: DRUG: fluticasone propionate/formoterol fumarate breath actuated inhaler|DRUG: Indacaterol maleate / glycopyrronium bromide capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of a HIIT Program on Quality of Life, Executive Functions, and IGF-1 Response in Sedentary Young University Women
Status: RECRUITING
Conditions: Insulin Growth Factor I Deficiency|IGF1 Deficiency|Executive Function Disorder
Interventions: BEHAVIORAL: HIIT|BEHAVIORAL: HIIT+PA|BEHAVIORAL: CON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Assessing the Efficacy of Abscopal Effect Induced by SBRT and Immunotherapy in Advanced NSCLC
Status: COMPLETED
Conditions: Non-Small-Cell Lung Cancer Stage IV
Interventions: DRUG: Bevacizumab|DRUG: Toripalimab|RADIATION: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcutaneous Tibial Nerve Stimulation in Patients With Neurogenic Overactive Bladder After Stroke
Status: NOT_YET_RECRUITING
Conditions: Urinary Bladder, Overactive
Interventions: OTHER: Transcutaneous tibial nerve stimulation (TTNS)|OTHER: Sham Transcutaneous tibial nerve stimulation (TTNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Clinical Study on Sitagliptin for Assessment of Glucose-lowering Effects (0431-045)
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: DRUG: sitagliptin phosphate|DRUG: Comparator: Placebo|DRUG: Comparator: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplasty
Status: TERMINATED
Conditions: Staphylococcal Infections|Methicillin-resistant Staphylococcus Aureus
Interventions: DRUG: Daptomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: HBOT Effect on Chronic Pain Syndrome With a History of Psychological Trauma
Status: COMPLETED
Conditions: Fibromyalgia|Chronic Pain Syndrome
Interventions: BIOLOGICAL: HBOT|BEHAVIORAL: Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aromatherapy With Thyme Oil on Disease Symptoms, Vital Signs, Hemodynamic Parameters in COVID-19 Patients
Status: COMPLETED
Conditions: Patient Engagement
Interventions: OTHER: thyme oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of the Vector Vaccine GamCovidVac for the Prevention of COVID-19 With Altered Antigenic Profile With Participation of Adult Volunteers
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: GamCovidVac vector vaccine for the prevention of COVID-19 (with altered antigenic profile)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults
Status: COMPLETED
Conditions: Vascular Stiffness|Insulin Sensitivity
Interventions: DRUG: Octreotide|DRUG: Insulin|DRUG: Dextrose 20% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Long Term Effect of Very-low-calories Ketogenic Diet on Weight Control and Cardiovascular Brisk Factors (KETOHEART)
Status: RECRUITING
Conditions: Obesity|Morbid Obesity
Interventions: OTHER: VLCKD|OTHER: r-MedDiet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fever and Neutropenia in Pediatric Oncology Patients
Status: WITHDRAWN
Conditions: Fever|Neutropenia
Interventions: DRUG: Low Risk: Oupatient Management|DRUG: Low Risk: Inpatient Management|DRUG: High Risk: Inpatient Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improving Effects of Fish Oil Combined With Pine Bark Extract on Cognitive Decline
Status: UNKNOWN
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: FOPE (fish oil + pine extract)|OTHER: FO (fish oil +placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Freeze Dried Strawberry Consumption on Gut Microbiota and Cardiovascular Health.
Status: COMPLETED
Conditions: Microbial Colonization|Cardiovascular Diseases|Obesity
Interventions: OTHER: Freeze Dried Strawberry Powder|OTHER: Isocaloric powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Safety of a Single Oral Dose of Solosec™ (Secnidazole) 2g for the Treatment of Adolescent Girls With BV
Status: COMPLETED
Conditions: Bacterial Vaginoses
Interventions: DRUG: Secnidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Flap Coverage in Severe Lower Extremity Trauma
Status: NOT_YET_RECRUITING
Conditions: Open Tibia Fracture|Open Dislocation of Ankle|Extremity Fracture Lower|Extremity Injuries Lower
Interventions: PROCEDURE: Accelerated Flap Coverage Surgery|PROCEDURE: Standard of Care Flap Timing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Peer Support in the ED (PCORI)
Status: NOT_YET_RECRUITING
Conditions: Psychomotor Agitation|Behavioral Disorder
Interventions: OTHER: Peer-Support Enhanced Agitation Code Team (PACT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Congenital Heart Disease
Interventions: DRUG: Dexmedetomidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of BMS-986202 in Healthy Subjects and to Treat Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: BMS-986202|DRUG: Placebo|DRUG: Interferon alpha-2a recombinant|DRUG: Famotidine|DRUG: Ustekinumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immunogenicity of Recombinant Anthrax Vaccine Compared With Anthrax Vaccine Adsorbed
Status: COMPLETED
Conditions: Bacillus Anthracis (Anthrax)
Interventions: BIOLOGICAL: AVA|BIOLOGICAL: rPA vaccine containing alhydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Combined Sedation With Midazolam and Dexmedetomidine in ICU Patients
Status: UNKNOWN
Conditions: Delirium
Interventions: DRUG: midazolam|DRUG: Dexmedetomidine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of the "7H" Intervention to Reduce Frequent Attendance in Primary Care
Status: COMPLETED
Conditions: Frequent Attenders
Interventions: BEHAVIORAL: New multicomponent "7H" intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Evaluate LY3202328 in Overweight Healthy Participants and Dyslipidemia
Status: COMPLETED
Conditions: Dyslipidemias
Interventions: DRUG: LY3202328|DRUG: Placebo|DRUG: Atorvastatin|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Operational Research for Cryptococcal Antigen Screening
Status: COMPLETED
Conditions: Cryptococcal Meningitis|Cryptococcus Neoformans|Cryptococcosis
Interventions: DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndromes|Relapsed/Refractory AML
Interventions: DRUG: Bexmarilimab|DRUG: Azacitidine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma
Status: COMPLETED
Conditions: Advanced Cancers|Lymphoma
Interventions: DRUG: Azacitidine|DRUG: Vorinostat|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|DRUG: Dexamethasone|OTHER: Caphosol|DRUG: Glutamine|DRUG: Pyridoxine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma
Status: COMPLETED
Conditions: Grade 3a Follicular Lymphoma|Recurrent Follicular Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Marginal Zone Lymphoma|Recurrent Small Lymphocytic Lymphoma|Refractory Follicular Lymphoma|Refractory Marginal Zone Lymphoma|Refractory Small Lymphocytic Lymphoma
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Lenalidomide|BIOLOGICAL: Obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Vaginal Microbiota and the Potential of a Vaginal Probiotic Cream in Vaginal Candidosis
Status: COMPLETED
Conditions: Candidiasis, Vulvovaginal
Interventions: OTHER: Probiotic vaginal gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib as Maintenance Therapy After Adjuvant Chemotherapy in Progressive Gastric Cancer With Positive Exfoliative Cancer Cells
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Epivir Plus Crixivan Combined With Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Lamivudine|DRUG: Stavudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Study of DC-CIK Cells as a Post-remission Treatment for Malignant Tumors
Status: UNKNOWN
Conditions: Malignant Neoplasm
Interventions: DRUG: Decitabine|BIOLOGICAL: DC-CIK
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Treatment of Perianal Crohn's Disease, Combining Medical and Surgical Treatment.
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: DRUG: Infliximab|PROCEDURE: Instillation of fibrin glue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of the Treatment of Sleep Apnea Syndrome by CPAP in Pharmacoresistant Epilepsy
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Epilepsies, Partial
Interventions: DEVICE: CPAP active|DEVICE: CPAP placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Renal Denervation in ADPKD- RDN-ADPKD Study
Status: RECRUITING
Conditions: Uncontrolled Hypertension|Autosomal Dominant Polycystic Kidney Disease|Renal Denervation
Interventions: DEVICE: Renal denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lasertherapy for Vulvodynia
Status: RECRUITING
Conditions: Vulvodynia
Interventions: DEVICE: Erbium:Yag laser|DEVICE: Sham Erbium:Yag laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postural Assessment of Stroke Patients by Pose Estimation and Effects of Dynamic Core Postural Chain Stabilization
Status: ACTIVE_NOT_RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Group A|BEHAVIORAL: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Determination of Automated Multiple Insulin Dose Injections Settings Using the MDI/SMBG Advisor for Patients With Type 1 Diabetes -Data Collection, Observational & Proof of Concept Study
Status: TERMINATED
Conditions: Type 1 Diabetes|Multiple Daily Injections
Interventions: DEVICE: MPSA Algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Family Health and Development Project
Status: COMPLETED
Conditions: Serious Emotional Disturbance
Interventions: BEHAVIORAL: Intensive In-home Child and Adolescent Psychiatric Service|BEHAVIORAL: Home-based Child Treatment Coordination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Take Rate, Immunogenicity and Safety of Elstree-BN Smallpox Vaccine in Healthy Vaccinia-Naive Subjects
Status: COMPLETED
Conditions: Smallpox
Interventions: BIOLOGICAL: Elstree-BN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: RESET System Pivotal Trial (Rev F)
Status: RECRUITING
Conditions: Diabetes type2|Obesity
Interventions: DEVICE: RESET Liner|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Continuous Glucose Monitoring System With Intensive Feedback in Adolescents With Poorly Controlled Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: CGMS Device|OTHER: No Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: MIDRIXNEO-LUNG Dendritic Cell Vaccine in Patients With Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: BIOLOGICAL: Dendritic cell immunotherapy|BIOLOGICAL: Antigen-specific DTH|BIOLOGICAL: Control DTH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of G-Pen Compared to Lilly Glucagon for Hypoglycemia Rescue in Adult Type 1 Diabetics
Status: COMPLETED
Conditions: Hypoglycemia|Diabetes Mellitus, Type 1
Interventions: DRUG: G-Pen (glucagon injection)|DRUG: Lilly Glucagon (glucagon injection [rDNA origin])
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Biomarker for the Evaluation of Response After Neoadjuvant Therapy in Patients With Pancreatic Cancer
Status: UNKNOWN
Conditions: Genetic Change|Chemotherapy Effect|Pancreatic Cancer
Interventions: DIAGNOSTIC_TEST: next generation sequencing|DIAGNOSTIC_TEST: following next generation sequencing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Valganciclovir Therapy in Infants and Children With Congenital CMV Infection and Hearing Loss
Status: COMPLETED
Conditions: Cytomegalovirus Infection
Interventions: OTHER: Placebo|DRUG: Valganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Proximal And Distal Tibiofibular Joint Manipulations on Foot Posture, Ankle Range of Motion, and Balance
Status: UNKNOWN
Conditions: Hemiplegia|Gait, Hemiplegic|Mobility Limitation
Interventions: OTHER: Proximal And Distal Tibiofibular Joint Manipulations|OTHER: Bobath Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: SHR6390 Plus Nab-paclitaxel and Gemcitabine in Advanced/Metastatic Pancreatic Cancer
Status: NOT_YET_RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: SHR6390|DRUG: Nab-paclitaxel|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results
Status: UNKNOWN
Conditions: Age Related Macular Degeneration
Interventions: DRUG: Intravitreal Aflibercept injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEMA Kwa Vijana Trial: Impact of an Adolescent Sexual and Reproductive Health Intervention in Mwanza, Tanzania
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases|Pregnancy|Sexual Behavior
Interventions: BEHAVIORAL: In-school Sexual Health Education|BEHAVIORAL: Youth-friendly health services|BEHAVIORAL: Youth condom promotion & distribution|BEHAVIORAL: Community activities related to adolescent sexual health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: ADAPT-Altering Diet for African American Populations to Treat Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: BEHAVIORAL: Dietary Approaches to Stop Hypertension-The DASH diet|BEHAVIORAL: Intervention with no dietary component - information regarding useful life skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis
Interventions: BIOLOGICAL: Injection (2x106 ASC/5ml).|BIOLOGICAL: Injection (10x106 ASC/5ml).|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sintilimab With Chemotherapy Plus PEG-rhG-GSF for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: PEG-rhG-GSF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate the Therapeutic Benefit of Fulvestrant in Combination With ZACTIMA in Postmenopausal Women With Bone Predominant, Hormone Receptor Positive Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Fulvestrant + ZACTIMA|DRUG: Fulvestrant + Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vestibulo-ocular Reflex Improving Exercise on Gait and Balance Among Post Stroke Sub Acute Patients
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: Physiotherapy including Vestibular rehabilitation|OTHER: conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Pelvic Patterns of Proprioceptive Neuromuscular Facilitation in the Pelvic Floor Muscles
Status: UNKNOWN
Conditions: Motor Activity
Interventions: OTHER: intervention group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Perioperative Treatment With Intravenous Glutamine on Myocardial Protection in Cardiac Surgery Patients With Aortic Stenosis
Status: UNKNOWN
Conditions: Aortic Valve Stenois
Interventions: DRUG: N(2)-L-Alanine L-Glutamine dipeptide|DRUG: placebo (0.9% NaCl (normal saline))
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intravenous Immunoglobulin for Unverricht-Lundborg Disease.
Status: UNKNOWN
Conditions: Unverricht-Lundborg Disease
Interventions: DRUG: Intravenous immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Nutritional Products for People With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: standard nutritional product (medical food)|OTHER: nutritional product for diabetes (medical food)|OTHER: diabetes specific experimental nutritional product (medical food)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Intensification With ZBEAM and Autologous Stem Cell Transplantation in Patients With High-grade B-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, Large Cell, Diffuse
Interventions: DRUG: ZBEAM (Zevalin, BCNU, Etoposide, Aracytine, Melphalan)|PROCEDURE: ASCT|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Controlled Trial of a Literacy Sensitive Decision Aid for Bowel Cancer Screening
Status: UNKNOWN
Conditions: Colorectal Neoplasms
Interventions: OTHER: Bowel cancer screening decision aid|OTHER: Bowel cancer screening decision aid|OTHER: Australian Government Bowel Cancer Screening booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: In Vivo Efficacy of Artemether-lumefantrine and Amodiaquine-artesunate in Mozambican Children
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Coartem™ (Artemether-lumefantrine combination)|DRUG: Coarsucam™ (Amodiaquine-artesunate combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Social Communication and Emotional Development in Under 5 Children
Status: UNKNOWN
Conditions: Early Childhood Developmental Disability (Disorder)
Interventions: BEHAVIORAL: Social Communication and Emotional Skill Development (SCESD) module
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness and Safety of Rhubarb for the Treatment of Patients Who Have Suffered From a Stroke
Status: UNKNOWN
Conditions: Pneumonia|Acute Stroke
Interventions: DRUG: rhubarb|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: DRUG: SSRIs|DIETARY_SUPPLEMENT: SSRI plus Sulforaphane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intubation Conditions of the Articulating Stylet and Intubating Stylet Guided Videolaryngoscopy
Status: COMPLETED
Conditions: Difficult Intubation
Interventions: DEVICE: articulating stylet|DEVICE: conventional stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Saroglitazar magnesium 4mg|DRUG: Placebos|DRUG: Moxifloxacin 400mg|DRUG: Saroglitazar magnesium 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Proprioceptive Training,Balance,Motor Function,Spastic Cerebral Palsy Patient
Status: UNKNOWN
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: Proprioceptive training|OTHER: Routine Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Adenocarcinoma|Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Ipilimumab|PROCEDURE: Local Consolidation Therapy|BIOLOGICAL: Nivolumab|OTHER: Quality-of-Life Assessment|RADIATION: Radiation Therapy|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acoustic and Vestibular Noise as Possible Non-pharmacological Treatment of ADHD in School Children
Status: RECRUITING
Conditions: ADHD
Interventions: DEVICE: Stochastic Vestibular Stimulation|DEVICE: Sham stimulation|DRUG: Active medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Intervention Study of Egg Protein Derivative on Cardiovascular Risk
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: Egg albumin-derived peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: FOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: DRUG: Ipilimumab|BIOLOGICAL: Vaccine|DRUG: FOLFIRINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: n-3 Fatty Acid Infusion and Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Intralipid +/- Omegaven
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML)
Interventions: DRUG: AMG 427
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adapting FAMS to Optimize CGM Use Among Emerging Adults With Type 1 Diabetes
Status: ENROLLING_BY_INVITATION
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: FAMS-T1D|BEHAVIORAL: Digital resources for diabetes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Triptorelin and Radiation Therapy in Treating Patients Who Have Undergone Surgery for Intermediate-Risk Stage III or Stage IV Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: triptorelin|PROCEDURE: adjuvant therapy|RADIATION: 3-dimensional conformal radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)
Status: RECRUITING
Conditions: Aortic Valve Stenosis|Cardiovascular Diseases|Heart Diseases|Heart Valve Diseases|Valve Disease, Aortic
Interventions: DRUG: Rivaroxaban|DRUG: Acetylsalicylic acid|DRUG: Clopidogrel|DRUG: Edoxaban|DRUG: Dabigatran|DRUG: Apixaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cetuximab (ERBITUX®) Added to Two Concurrent Chemoradiotherapy Platforms in Locally Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab|DRUG: 5-FU|DRUG: Hydroxyurea|RADIATION: Twice-daily radiation|DRUG: Cisplatin|RADIATION: Accelerated fraction radiotherapy with concomitant boost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chios Mastic Mouthwash and Halitosis and Oral Hygiene in Orthodontic Patients
Status: COMPLETED
Conditions: Halitosis|Orthodontic Appliance Complication
Interventions: DIETARY_SUPPLEMENT: Mastic mouthwash|DIETARY_SUPPLEMENT: Placebo mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Empowered Relief for Youth
Status: RECRUITING
Conditions: Chronic Pain|Musculoskeletal Pain|Fibromyalgia|Neuropathic Pain|Complex Regional Pain Syndromes|Abdominal Pain
Interventions: BEHAVIORAL: Empowered Relief for Youth
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mechanical Bowel Preparation Prior to Gynaecological Laparoscopic Surgeries on the Surgical Conditions
Status: UNKNOWN
Conditions: Patient Preference|Patient Safety
Interventions: OTHER: Mechanical Bowel Preparation|DIETARY_SUPPLEMENT: Low fibre diet|OTHER: MBP plus low-fibre diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Safety and the Effects of Isolated Left Ventricular Pacing in Patients With Bradyarrhythmias
Status: UNKNOWN
Conditions: Bradyarrhythmias|Arrhythmias|Atrioventricular Block|Ventricular Dysfunction|Cardiovascular Disease
Interventions: DEVICE: Left ventricular pacing through coronary sinus tributaries (Attain StarFix)|DEVICE: Right ventricular pacing (Medtronic)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy With or Without Chemotherapy in Treating Patients With Anaplastic Oligodendroglioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: lomustine|DRUG: procarbazine hydrochloride|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Art Therapy Applied to Mothers on Eating Behavior in Children
Status: RECRUITING
Conditions: Eating Behavior
Interventions: BEHAVIORAL: Art therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: PREEMPTİVE PARA-CERVİCAL BLOCK FOR POSTOPERATİVE PAIN AFTER LAPAROSCOPIC HYSTERECTOMY
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: PROCEDURE: Para-cervical block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Efficacy and Safety of DA-8010 in Patients With Overactive Bladder
Status: COMPLETED
Conditions: Overactive Bladder
Interventions: DRUG: DA-8010 Placebo|DRUG: DA-8010 2.5mg|DRUG: DA-8010 5mg|DRUG: Solifenacin 5mg|DRUG: Solifenacin succinate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: fowlpox virus vaccine vector|BIOLOGICAL: gp100 antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomised Study Comparing the Effects of Inhaled Fluticasone Furoate (FF)/Vilanterol (VI; GW642444M) Combination and FF on an Allergen Induced Asthmatic Response
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Fluticasone Furoate|DRUG: FF/Vilanterol (VI; GW642444M)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: In Vitro Maturation (IVM) of Human Oocytes
Status: WITHDRAWN
Conditions: Polycystic Ovarian Syndrome (PCOS)|Patients Sensitive to Exogenous Gonadotropins|Ovarian Hyper Stimulation Syndrome (OHSS)
Interventions: BIOLOGICAL: In Vitro maturation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders
Status: COMPLETED
Conditions: Schizophrenia|Suicide
Interventions: BEHAVIORAL: Enhanced Treatment as Usual|BEHAVIORAL: Coping Long-term with Active Suicide Program for Schizophrenia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Remote Ischemic Perconditioning on Acute Kidney Injury in Adult Valve Replace
Status: UNKNOWN
Conditions: Rheumatic Disease of Heart Valve|Ischemic Reperfusion Injury
Interventions: DEVICE: Remote ischemic postconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALL
Status: RECRUITING
Conditions: Acute B Lymphoblastic Leukemia|Allogeneic Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-term Effects of Exercise Program Versus Electropuncture in Patients With Chronic Non-specific Low Back Pain: A Randomized Clinical Trial.
Status: COMPLETED
Conditions: Low Back Pain|Exercise Program|Electroacupuncture
Interventions: OTHER: Percutaneous electrostimulation treatment (EPS)|OTHER: Exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy And Safety Of Short Course Antibiotic Therapy In Preterm Neonates With Early Onset Sepsis
Status: COMPLETED
Conditions: Early-Onset Neonatal Sepsis|Antibiotic Stewardship
Interventions: OTHER: Short duration antibiotics|OTHER: Standard duration antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension Participants
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension
Interventions: DRUG: Imatinib|DRUG: Sildenafil|DRUG: Bosentan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Evolution of Wound Biomarkers in Venous Leg Ulcers Treated With KLOX Biophotonic System
Status: UNKNOWN
Conditions: Venous Leg Ulcer
Interventions: DEVICE: KLOX BioPhotonic System (single treatment)+SOC|DEVICE: KLOX BioPhotonic System (consecutive treatments)+SOC|OTHER: Standard of Care (SOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Efficacy and Safety of P-3074 Topical Solution in the Treatment of Androgenetic Alopecia
Status: COMPLETED
Conditions: Alopecia, Androgenetic
Interventions: DRUG: P-3074|DRUG: Finasteride|DRUG: P-3074 Vehicle|DRUG: Finasteride Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cytokines in Patients With Metastatic Renal Cell Carcinoma of Intermediate Prognosis
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Interleukin-2|DRUG: Interferon alfa|DRUG: medroxyprogesterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Rocabado Approach Versus Postural Correction Exercises on Kinesiophobia and Interincisal Distance in Patients With Temporo-Mandibular Dysfunction
Status: RECRUITING
Conditions: Temporo-mandibular Dysfunction
Interventions: OTHER: Rocabdo exercises|OTHER: Postural correction exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hormone Replacement Therapy and Insulin Action: A Double-Blind, Parallel, Placebo-Controlled Hormone Intervention Study in Postmenopausal Women
Status: UNKNOWN
Conditions: Menopause
Interventions: DRUG: Hormone Replacement Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Iloprost (Ventavis): Efficacy, Safety, and Pharmacokinetics (PK) Confirmation Study
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Iloprost (Ventavis inhaled, BAYQ6256)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Smartphone App for 6-18 Years With T1DM - RCT
Status: UNKNOWN
Conditions: Type1 Diabetes Mellitus
Interventions: DEVICE: Intervention arm - A new smartphone application for pediatric type 1 DM|OTHER: Standard diabetic eduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: AKT Inhibitor in Oestrogen Positive Breast Cancer
Status: COMPLETED
Conditions: Invasive Breast Cancer
Interventions: DRUG: AZD5363
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: H5N1 (Clade 2) Vaccination of Adults and Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza Virus Vaccine, Monovalent A/H5N1 A/Indonesia/05/2005
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Banaba (Lagerstroemia Speciosa) on Metabolic Syndrome, Insulin Secretion and Insulin Sensitivity
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DRUG: Banaba|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project
Status: COMPLETED
Conditions: 30% Oxygen Concentration During Colorectal Surgery|80% Oxygen Concentration During Colorectal Surgery
Interventions: DRUG: 30% oxygen|DRUG: 80% oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication
Status: RECRUITING
Conditions: Cardiac Inflammation
Interventions: OTHER: Cardiac ECG-gated PET imaging will added
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma
Status: COMPLETED
Conditions: Breast Cancer|Endometrial Cancer|Kidney Cancer|Lung Cancer|Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: metformin hydrochloride|DRUG: temsirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Effect of Transcranial Direct Current Stimulation (tDCS) and Physical Activity on Gait and Functional Mobility in Participants With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: active tDCS|DEVICE: sham tDCS|OTHER: Physical Activity (PA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Curative Effect and Quality of Life Between Uniportal and Open Sleeve Lobectomy for Central Type Lung Cancer
Status: RECRUITING
Conditions: Video-Assisted Thoracic Surgery|Lung Cancer
Interventions: PROCEDURE: uniportal sleeve lobectomy|PROCEDURE: open sleeve lobectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Establish a Telecare Model of Acute Coronary Syndrome Patient With Heart Stent Implantation by a Non-invasive Wearable Device and Artificial Intelligence Cloud to Reducing Medical Adverse Events.
Status: UNKNOWN
Conditions: Acute Coronary Syndrome|Percutaneous Transluminal Coronary Angioplasty
Interventions: DEVICE: use EKG Wisdom bracelet
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Hysterectomy
Interventions: DRUG: IV Acetaminophen|DRUG: IV Placebo 100 mL solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating Efficacy and Safety of CRO-SBT in the Treatment of Gonorrhea
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: Ceftriaxone sodium and Sulbactam Sodium for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Internet-delivered ACT (I-Navigator ACT) for Parents of Children With Disabilities
Status: ACTIVE_NOT_RECRUITING
Conditions: Parents|Stress, Psychological|Anxiety|Depression|Neurodevelopmental Disorders|Autism Spectrum Disorder|Attention Deficit Hyperactivity Disorder|Intellectual Disability|Physical Disability|Traumatic Brain Injury
Interventions: BEHAVIORAL: I-Navigator ACT|BEHAVIORAL: Navigator ACT group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate Safety and Efficacy of 2 Doses of Quizartinib in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Leukemia, Myeloid, Acute
Interventions: DRUG: AC220
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT