pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized Controlled Clinical Trial of Surgery Versus Conservative Treatment for Mild and Moderate-grade Nasopharyngeal Necrosis
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma, Postradiation, Necrosis, Endoscopy Surgery, Conservative Treatment
Interventions: PROCEDURE: Curative-intent endoscopic necrectomy followed by reconstruction using the posterior pedicle nasal septum and floor mucoperiosteum flap|PROCEDURE: Conservative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Immunogenicity of Booster SARS-CoV-2 Vaccine (Vero Cell)
Status: UNKNOWN
Conditions: COVID-19
Interventions: BIOLOGICAL: SARS-COV-2 Vaccine (Vero Cell-Sinopharm) Inactivated
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Adolescent Skills for Emotions (EASE)-Pilot Cluster Randomized Controlled Trial (cRCT) in Public Schools of Rural Pakistan
Status: COMPLETED
Conditions: Psychological Distress|Emotional Problem|Anxiety|Depression
Interventions: BEHAVIORAL: Early Adolescent Skills for Emotions (EASE) Program|OTHER: Treatment As Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Single Doses of BIIB059 in Healthy Japanese Subjects.
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: BIIB059|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound-guided Thoracic Paravertebral Block Using Ropivacaine With/Without Dexamethasone in Elective Thoracotomy
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Ropivacaine|DRUG: Dexamethasone|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Minimal Invasive Coronary Surgery in Patients With Complex Coronary Artery Lesions
Status: UNKNOWN
Conditions: Coronary Artery Bypass, Off-Pump
Interventions: PROCEDURE: Minimal invasive coronary surgery|PROCEDURE: Off-pump coronary artery bypass surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of an International Commercial Program on Weight Loss and Health Outcomes
Status: COMPLETED
Conditions: Weight Loss|Weight Change, Body|Obesity|Diet Modification
Interventions: BEHAVIORAL: Weight Watchers Freestyle (Flex)|BEHAVIORAL: DIY Personal Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)
Status: COMPLETED
Conditions: Urothelial Carcinoma|Carcinoma, Non-Small Cell Lung|Small Cell Lung Carcinoma|Triple Negative Breast Carcinoma|Hepatocellular Carcinoma
Interventions: DRUG: Atezolizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Inhaled Corticosteroids on Sputum Bacterial Load in COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Salmeterol/Fluticasone combination|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naive Adults With Chronic HCV Genotype 3 Infection
Status: COMPLETED
Conditions: Hepatitis C Virus Infection
Interventions: DRUG: LDV/SOF|DRUG: RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Decitabine and Cedazuridine|DRUG: Enasidenib|DRUG: Ivosidenib|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tepotinib Plus Paclitaxel in MET Amplified or MET Exon 14 Alterated Gastric and GEJ Carcinoma
Status: RECRUITING
Conditions: Gastric Cancer|Gastroesophageal-junction Cancer
Interventions: DRUG: Tepotinib plus paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Adding Dexamethasone in the Quadratus Lumborum Block
Status: UNKNOWN
Conditions: Analgesia|Motor Activity
Interventions: PROCEDURE: Quadratus Lumborum block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Follow-up Study of Autologous Transplantation of P63+ Lung Progenitor Cells for Treatment of Bronchiectasis
Status: NOT_YET_RECRUITING
Conditions: Bronchiectasis
Interventions: OTHER: RNA sequencing is performed on the remaining LPCs|OTHER: Immunofluorescence staining is performed in the surgically resected lung tissue sections
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy Study of Zinc Supplementation on Anemia, Oxidative Stress and Inflammation in Hemodialysis Patients
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: DIETARY_SUPPLEMENT: Zinc Sulphate|OTHER: Corn Starch filled Hard Gel Capsules|DRUG: Epoetin alfa 2000-4000 IU solution for injection|DRUG: Iron Hydroxide Saccharate Complex Solution for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Nutritional Status in the Patient With Liver Cirrhosis
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Branched chain amino acids (BRCA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pregabalin Treatment for RDEB Pain and Itch
Status: COMPLETED
Conditions: Pain, Neuropathic|Itch|Epidermolysis Bullosa
Interventions: DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)
Status: TERMINATED
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DRUG: BMS-986263|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of LY03010 Compared to Listed Drug
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders|Mood Disorders|Schizophrenia Spectrum|Mental Disorders|Antipsychotic Agents|Tranquilizing Agents|Central Nervous System Depressants|Physiological Effects of Drugs|Psychotropic Drugs|Neurotransmitter Agents|Molecular Mechanisms of Pharmacological Action
Interventions: DRUG: LY03010; paliperidone palmitate|DRUG: INVEGA SUSTENNA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapy for Migraine Prevention in Children 6-11 Years of Age
Status: TERMINATED
Conditions: Migraine Disorders|Headache Disorders
Interventions: DRUG: SPN-538|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health Improvement for Baltimore Youth
Status: COMPLETED
Conditions: HIV|Adolescent Development|Adolescent Behavior|Medication Adherence
Interventions: BEHAVIORAL: MBSR Program|BEHAVIORAL: HT Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Status: COMPLETED
Conditions: Sleep Apnea Syndromes|Oxidative Stress|Cardiovascular Diseases
Interventions: DEVICE: Continuous Positive Airway Pressure (CPAP)|DEVICE: Sham CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Post Operative Pain After Using Two Different Types of Sealers
Status: RECRUITING
Conditions: Post Operative Pain
Interventions: OTHER: root canal sealers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Neurokinin Receptor Antagonist Associated to Ondansetron in PONV
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: Aprepitant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Angiotensin Receptor Blockers and Angiotensin-converting Enzyme Inhibitors and Adverse Outcomes in Patients With COVID19
Status: UNKNOWN
Conditions: Corona Virus Infection|COVID-19
Interventions: OTHER: Suspension or Maintenance of Angiotensin Receptor Blockers and Angiotensin-converting Enzyme Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of PriorixTetra™ When Co-administered With Conjugated MenC Vaccine in Healthy Children
Status: COMPLETED
Conditions: Rubella|Varicella|Measles|Mumps
Interventions: BIOLOGICAL: PriorixTetra™|BIOLOGICAL: Meningitec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of V503 Vaccine Given Concomitantly With REPEVAX™ in 11 to 15 Year Olds (V503-007)
Status: COMPLETED
Conditions: Papillomavirus Infections
Interventions: BIOLOGICAL: V503 Vaccine|BIOLOGICAL: REPEVAX™ (Concomitant)|BIOLOGICAL: REPEVAX™ (Non-concomitant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: At High-risk for Pre-eclampsia After Assisted Reproductive Technology
Status: RECRUITING
Conditions: Pre-Eclampsia
Interventions: PROCEDURE: endometrium biopsy|DIAGNOSTIC_TEST: Transabdominal ultrasound|DIAGNOSTIC_TEST: Peripheral phlebotomy|DIAGNOSTIC_TEST: Urine collection|OTHER: MOCK frozen embryo transfer preparative cycle.|DIAGNOSTIC_TEST: Baseline questionnaire|OTHER: collection of menstrual blood|DIAGNOSTIC_TEST: nutritional and metabolic work-up|DIAGNOSTIC_TEST: cardiac work-up|DIAGNOSTIC_TEST: Blood pressure measurement
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Trial to Evaluate the Safety and Immunogenicity of Quadrivalent Influenza Vaccine (15µg/0.5ml)
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine|BIOLOGICAL: Trivalent influenza vaccine (contains B/Victoria strain)|BIOLOGICAL: Trivalent influenza vaccine (contains B/Yamagata strain)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of UGIR in Adults With Compromised Gut Function and Malabsorption
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Crohn Disease|Ulcerative Colitis|Celiac Disease
Interventions: OTHER: Nutrition Support Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First Evaluation of the Moda-Flx Hemodialysis System™ in Real World Clinical Settings
Status: NOT_YET_RECRUITING
Conditions: End Stage Renal Disease|End Stage Renal Disease on Dialysis|End Stage Kidney Disease
Interventions: DEVICE: Moda-flx Hemodialysis System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ERA Test in Patients With Recurrent Implantation Failure
Status: UNKNOWN
Conditions: Repetitive Implantation Failure
Interventions: OTHER: ERA (Endometrial Receptivity Array)|OTHER: Personalized Embryo Transfer|OTHER: Second ERA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Open and Exploratory Trial to Investigate the Pharmacokinetic of Ceftobiprole Medocaril in Patients With CSF Device
Status: COMPLETED
Conditions: Inflamed Meninges|Suspected Meningitis|Ventriculitis
Interventions: DRUG: Ceftobiprole Medocaril|OTHER: Blood samples and cerebrospinal fluid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian Cancer
Status: WITHDRAWN
Conditions: Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Pancreatic Cancer|Stage III Pancreatic Cancer|Stage IIIA Ovarian Epithelial Cancer|Stage IIIA Ovarian Germ Cell Tumor|Stage IIIB Ovarian Epithelial Cancer|Stage IIIB Ovarian Germ Cell Tumor|Stage IIIC Ovarian Epithelial Cancer|Stage IIIC Ovarian Germ Cell Tumor|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Stage IV Pancreatic Cancer
Interventions: OTHER: palliative care|BEHAVIORAL: educational intervention|PROCEDURE: quality-of-life assessment|OTHER: questionnaire administration|BEHAVIORAL: telephone-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma
Status: COMPLETED
Conditions: HIV|Burkitt's Lymphoma
Interventions: DRUG: Induction Phase|DRUG: Consolidation Phase (on day +50)|DRUG: Intensification phase|DRUG: BEAM conditioning|RADIATION: Consolidation radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Non-randomized Evaluation of Oncoplastic Surgery
Status: UNKNOWN
Conditions: Breast Image Scale Index for Self Esteem Evaluation|Breast Symmetry Index|Quality of Life|Morbidity|Oncological Outcome
Interventions: PROCEDURE: Breast Surgery|PROCEDURE: Breast Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Safety and Immune Response Study to Evaluate Varying Doses of an mRNA Vaccine Against Coronavirus Disease 2019 (COVID-19) in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: mRNA-CR-04 vaccine 10μg|BIOLOGICAL: mRNA-CR-04 vaccine 30μg|BIOLOGICAL: mRNA-CR-04 vaccine 100μg|DRUG: Placebo|BIOLOGICAL: mRNA-CR-04 vaccine 3μg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Mifepristone and Buccal Misoprostol Administered Simultaneously for Abortion Through 63 Days Gestation
Status: COMPLETED
Conditions: Abortion, Induced
Interventions: DRUG: mifepristone, misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Different Pain Management Techniques in Pediatric Patients Undergoing a Hernia Repair
Status: COMPLETED
Conditions: Pain|Inguinal Hernia
Interventions: PROCEDURE: TAP Block|PROCEDURE: Ilioinguinal/iliohypogastric blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PTX-200, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide in Treating Patients With Stage IIB-IV Breast Cancer
Status: TERMINATED
Conditions: Breast Adenocarcinoma|Estrogen Receptor Positive|HER2/Neu Negative|Recurrent Breast Carcinoma|Stage IIB Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer|Stage IV Breast Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: Doxorubicin Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Triciribine Phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AK105 Plus Anlotinib Hydrochloride Combined With Albumin Paclitaxel as a First-line Therapy in Patients With Advanced Triple-negative Breast Cancer
Status: UNKNOWN
Conditions: Breast Neoplasm Female
Interventions: DRUG: AK105|DRUG: Anlotinib hydrochloride|DRUG: Albumin Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction
Status: COMPLETED
Conditions: Erectile Dysfunction|Erectile Dysfunction With Diabetes Mellitus
Interventions: DRUG: Tadalafil 5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of L-Citrulline or Citrulline-malate on Neuromuscular Performance in Resistance-trained Adults
Status: COMPLETED
Conditions: Neuromuscular Performance
Interventions: DIETARY_SUPPLEMENT: L-citrulline|DIETARY_SUPPLEMENT: Citrulline-malate|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Desoximetasone Spray 0.25%, Hypothalamic Pituitary Adrenal (HPA) Axis Study
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: Desoximetasone 0.25% spray
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of the "MINDLiNG" Digital Mental Health Intervention
Status: COMPLETED
Conditions: Mental Health Services|Personality
Interventions: DEVICE: "MINDLiNG" Digital Mental Health Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Research Study Investigating How Semaglutide and Dapagliflozin Act in Your Body When Dosed in One Tablet
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Semaglutide|DRUG: Dapagliflozin|DRUG: Semaglutide/dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dual Versus Single Shock for Cardioversion of Atrial Fibrillation
Status: TERMINATED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Double shock|DEVICE: Single shock
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Stents In The Critically Ischemic Lower Leg
Status: COMPLETED
Conditions: Peripheral Vascular Disease|Critical Limb Ischemia
Interventions: DEVICE: XIENCE V everolimus eluting coronary stent system|DEVICE: MULTILINK VISION coronary stent system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ORAL T-6: Oral Androgens in Man-6
Status: COMPLETED
Conditions: Contraception|Hypogonadism
Interventions: DRUG: Acyline|DRUG: Testosterone|DRUG: Finasteride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer
Status: NOT_YET_RECRUITING
Conditions: ASCVD|Atherosclerotic Cardiovascular Disease|Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor|Cancer
Interventions: DRUG: Evolocumab|DRUG: Statin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Individualized Treatment of 6-mercaptopurine in Children With Acute Lymphoblastic Leukemia in China
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia, Pediatric
Interventions: DRUG: 6-mercaptopurine|PROCEDURE: Standard treatment|PROCEDURE: Individualized treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risperidone-controlled,Multicentre Clinical Trial of Iloperidone in Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Iloperidone|DRUG: Risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial
Status: RECRUITING
Conditions: Locally Advanced Cervical Carcinoma|Locally Advanced Cervical Cancer|Locally Advanced Pancreas Cancer|Locally Advanced Pancreatic Carcinoma|Locally Advanced Pancreatic Cancer|Cervical Cancer|Pancreas Cancer|Pancreatic Cancer|Cancer of the Cervix|Cancer of the Pancreas
Interventions: OTHER: Tumor collection via biopsy|OTHER: Blood collection|DEVICE: Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Implementation of a Patient-centered Self-management Program in Patients With Hypertensive Nephropathy
Status: COMPLETED
Conditions: Hypertensive Nephropathy|Self-management|Self-efficacy|Mental Health Wellness 1
Interventions: BEHAVIORAL: PCSMP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Endocannabinoid Activity Remodulation for Psychosis Liability in Youth
Status: RECRUITING
Conditions: Clinical High Risk for Psychosis|Ultra High Risk for Psychosis|Attenuated Psychotic Symptoms
Interventions: DIETARY_SUPPLEMENT: Ultra-micronized Palmitoylethanolamide (PEA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label High Dose Ropinirole (Requip) Study for Patients With Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: DRUG: Ropinirole Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: MSP008-22|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)
Status: ENROLLING_BY_INVITATION
Conditions: Postoperative Atelectasis|Postoperative Hypoxemia|Postoperative Pneumonia|Postoperative Pulmonary Complications|Patient Adherence|Incentive Spirometry|Respiratory Therapy|Respiratory Insufficiency
Interventions: DEVICE: Alarms
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abemaciclib in Newly Diagnosed Meningioma Patients
Status: NOT_YET_RECRUITING
Conditions: Meningioma
Interventions: DRUG: Abemaciclib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Study of Two Doses of Tranexamic Acid During Cardiac Surgery
Status: COMPLETED
Conditions: Cardiopulmonary Bypass|Hemorrhage
Interventions: DRUG: tranexamic acid|DRUG: tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: ALKS 4230|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults
Status: COMPLETED
Conditions: Infections, Meningococcal
Interventions: COMBINATION_PRODUCT: rMenB+OMV NZ vaccine|BIOLOGICAL: Meningococcal Groups A, C, W and Y Conjugate Vaccine (MenACWY)|COMBINATION_PRODUCT: Placebo|COMBINATION_PRODUCT: MenABCWY-1|COMBINATION_PRODUCT: MenABCWY-2|COMBINATION_PRODUCT: MenABCWY-3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nintedanib and Weekly Docetaxel in Lung Adenocarcinoma
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Docetaxel|DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Nintedanib|DRUG: Nintedanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Early Stage Mini-invasive Abdominal Drainage on Complications and Prognosis of SAP
Status: UNKNOWN
Conditions: Pancreatitis
Interventions: OTHER: Early stage abdominal drainage|OTHER: Late stage abdominal drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pantoprazole Sodium 40 mg DR Tablets Under Non-Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Pantoprazole Sodium 40 mg delayed-release tablets|DRUG: PROTONIX® 40 mg delayed-release tablets.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Computerized Cognitive-Behavioral Therapy for Auditory Hallucinations
Status: COMPLETED
Conditions: Schizophrenia, Schizoaffective Disorder
Interventions: BEHAVIORAL: Computer CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Bioavailability Study of Topiramate Oral Liquid Formulation Compared to the Marketed Sprinkle Capsule Formulation in Healthy Adults
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Topiramate oral liquid formulation;Topiramate Sprinkle formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Two Different Schedules of Palbociclib + Second Line Endocrine Therapy in Estrogen Receptor Positive, HER2 Neg Advanced/Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Palbociclib 100mg|DRUG: Palbociclib 125mg|DRUG: Fulvestrant or Tamoxifen or Aromatase Inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Positive End-expiratory Pressure on Intracranial Pressure in Patients With Severe Traumatic Brain Injury
Status: COMPLETED
Conditions: Traumatic Brain Injury|Mechanical Ventilation Complication
Interventions: OTHER: PEEP at 5cmH2O|OTHER: PEEP at 10cmH2O|OTHER: PEEP at 15cmH2O
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Administration of Rifaximin to Improve Liver Regeneration and Outcome Following Major Liver Resection
Status: TERMINATED
Conditions: Malignant Liver Disease|Major Liver Resection
Interventions: DRUG: XIFAXAN® (Rifaximin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Safety of NeuroFlo in Stroke Patients Receiving Tissue Plasminogen Activator
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DEVICE: NeuroFlo catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: QUAPELLA (QUAlity of Prostate Enucleation by LUMENIS - Laser)
Status: COMPLETED
Conditions: Benign Prostatic Hyperplasia
Interventions: PROCEDURE: Holmium Laser Enucleation of the Prostate (HoLEP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: BIBW 2992 (Afatinib) vs Gemcitabine-cisplatin in 1st Line Non-small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Adenocarcinoma
Interventions: DRUG: Gemcitabine+Cisplatin|DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain|Stage IV Non-Small Cell Lung Cancer AJCC v7
Interventions: PROCEDURE: Cognitive Assessment|BIOLOGICAL: Ipilimumab|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|RADIATION: Stereotactic Radiosurgery|RADIATION: Whole-Brain Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Education on Vaginal Effects of Menopausal Women
Status: NOT_YET_RECRUITING
Conditions: Menopause|Aging|Failure of Genital Response
Interventions: BEHAVIORAL: menopause education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prospective Trial Comparing Oxybutynin and Tamsulosin for Stent Pain in the Pediatric Population
Status: UNKNOWN
Conditions: Disorder of Urinary Stent
Interventions: DRUG: Tamsulosin|DRUG: Oxybutynin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Treatment Regimen Study of ST266 in Subjects With Moderate to Severe Periodontitis
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: BIOLOGICAL: ST266|DRUG: Saline (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Melodies: How Classical Turkish Music Soothes Stress and Eases Loneliness
Status: COMPLETED
Conditions: Stress|Loneliness|COVID-19 Pandemic|Elderly
Interventions: BEHAVIORAL: Classical Turkish Music Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Species-specific Bacterial Detector for Fast Pathogen Diagnosis of Severe Pneumonia
Status: NOT_YET_RECRUITING
Conditions: Severe Pneumonia
Interventions: DIAGNOSTIC_TEST: results of SSBD are used to guide antibiotics adjustment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Masks on Metabolic Parameters and Inspiratory Muscle Strength During Aerobic Exercise
Status: COMPLETED
Conditions: Masks
Interventions: DIAGNOSTIC_TEST: steady intensity aerobic test of 30 minutes long
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of Niraparib Combined With Bevacizumab Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: DRUG: Niraparib|BIOLOGICAL: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Group-Delivered Revised Guided Written Exposure Therapy for PTSD and Subclinical PTSD Among Chinese Adolescents
Status: RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Group-delivered guided written exposure therapy-revised version|BEHAVIORAL: Waiting-List (WL) condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.
Status: COMPLETED
Conditions: Cardiorenal Syndrome
Interventions: DRUG: Furosemide intravenous solution|DRUG: Chlortalidone|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BNC105P Combination Study in Partially Platinum Sensitive Ovarian Cancer Patients
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: BNC105P
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Duloxetine in Adult Attention Deficit Hyperactivity Disorder(ADHD)
Status: COMPLETED
Conditions: Attention Deficit Disorder With Hyperactivity
Interventions: DRUG: duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Patient Education on Benzodiazepine Use in the Elderly
Status: WITHDRAWN
Conditions: Anxiety|Insomnia
Interventions: BEHAVIORAL: Educational booklet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Diurnal Variation of Exogenous Peptides (Endogenous Insulin Jurgita II)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Insulin Aspart 100 IE/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Chemo-Radioimmunotherapy Followed by Autologous Transplantation for Patients With Untreated Advanced Stage Mantle Cell Lymphoma
Status: COMPLETED
Conditions: Mantle Cell Lymphoma
Interventions: OTHER: R-CHOP-14R-HIDAC,followed by RIT/HDT/ASCR.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 16 Week Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Placebo|DRUG: PF-06882961
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Feasibility of a Personalized Treatment for Depression With Co-Occurring Anxiety
Status: COMPLETED
Conditions: Depression|Anxiety
Interventions: BEHAVIORAL: Interpersonal Psychotherapy for Depression with Panic and Anxiety Symptoms (IPT-PS)|BEHAVIORAL: Brief Supportive Psychotherapy (BSP)|DRUG: Citalopram hydrobromide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Effect of the 'Wavy' Application, on Stress and Burden of Disease in Women With INOCA
Status: COMPLETED
Conditions: Stress|Ischemia|Vasospasm, Coronary|Vasomotor; Spasm|Angina, Stable|Prinzmetal Angina
Interventions: BEHAVIORAL: Wavy stress application
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Efficacy of Crano-cure inTreatment of Urinary Tract Infection
Status: COMPLETED
Conditions: Urinary Tract Infections
Interventions: DIETARY_SUPPLEMENT: Crano-cure|DRUG: Ciprofloxacin 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparison Between Bandage Contact Lens, Punctal Plugs and Standard Measures in Preventing Corneal Injuries
Status: UNKNOWN
Conditions: Contact Lens and Punctal Plug in Preventing Corneal Injuries
Interventions: DEVICE: contact lens|DEVICE: punctal plug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer|Chemotherapy Effect
Interventions: DRUG: FLOT Chemotherapy|DRUG: SOX Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation for Patients With Chronic, Severe and Resistant Anorexia Nervosa
Status: UNKNOWN
Conditions: Anorexia Nervosa
Interventions: DEVICE: Deep brain stimulation ON|DEVICE: Deep brain stimulation OFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Education Effectiveness for Type 1 Diabetes Mellitus on Insulin Pump Therapy
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: BEHAVIORAL: Education by structured programme|DEVICE: CSII|DEVICE: CGM-RT|PROCEDURE: Screening for Complications|PROCEDURE: Glycaemic control assessment|PROCEDURE: QoL assessment|PROCEDURE: Knowledge assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health After eaRly Menopause Due to Oophorectomy
Status: UNKNOWN
Conditions: Surgical Menopause|BRCA1 Mutation|BRCA2 Mutation|Cardiovascular Diseases|Bone Mineral Density|Cognitive Decline|Quality of Life|Menopause Surgical
Interventions: DIAGNOSTIC_TEST: CAC-score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: FAPi Radioligand OpeN-Label, Phase 1 Study to Evaluate Safety, Tolerability and DosImetry of [Lu-177]-PNT6555; A Dose Escalation Study for TReatment of Patients With Select Solid Tumors (FRONTIER)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Ductal Adenocarcinoma|Colorectal Cancer|Esophageal Cancer|Melanoma (Skin)|Soft Tissue Sarcoma|Head and Neck Squamous Cell Carcinoma|Cholangiocarcinoma
Interventions: DRUG: [Ga-68]-PNT6555|DRUG: [Lu-177]-PNT6555
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: On Dose Efficiency of Modern CT-scanners in Chest Scans
Status: COMPLETED
Conditions: Pneumonia|Lung Cancer|Pulmonary Embolism|Pulmonary Disease|Aortic Stenosis
Interventions: DIAGNOSTIC_TEST: Imaging on Scanner with Spectral Imaging Capabilities|DIAGNOSTIC_TEST: CT Scan using an Energy-Integrating Detector CT (128 slice MDCT)|DIAGNOSTIC_TEST: CT Scan using an Energy-Integrating Detector CT (20-slice MDCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Virtual Group Psychoeducational Discussions With Spanish-Speaking Mothers of Infants in Pediatric Primary Care
Status: RECRUITING
Conditions: Postpartum Depression|Postpartum Anxiety
Interventions: BEHAVIORAL: Single-Session Virtual Group Psychoeducational Session about Postpartum Depression
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Combined Treatment With Er:YAG & Nd:YAG Lasers for the Treatment of Recalcitrant Warts
Status: COMPLETED
Conditions: Viral Wart
Interventions: DEVICE: Long-Pulsed Nd:YAG Laser 1064nm & Er:YAG Laser 2940nm|DEVICE: Er:YAG Laser 2940nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
Status: COMPLETED
Conditions: Sedation, Bronchoscopy
Interventions: DRUG: Midazolam|DRUG: Propofol-Lipuro|DRUG: morphine-scopolamine|DRUG: Glycopyrrolate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Dry Needling in the Treatment of Lateral Epicondylitis
Status: COMPLETED
Conditions: Tennis Elbow|Dry Needling
Interventions: OTHER: Dry needling|OTHER: Home exercise program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD
Status: COMPLETED
Conditions: Chronic Obstructive Lung Disease|Acute Exacerbation of COPD|Comorbidities and Coexisting Conditions
Interventions: OTHER: Frequency of AECOPD
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Environmental Tobacco Smoke Exposure Reduction in High-Risk Preteens
Status: COMPLETED
Conditions: Lung Diseases|Asthma
Interventions: BEHAVIORAL: Counseling|BEHAVIORAL: Urine Cotinine Feedback|BEHAVIORAL: Contingent Incentives|BEHAVIORAL: Usual education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: SHEN211 Tablets for the Treatment of Mild and Moderate Novel Corona Virus Infections (COVID-19)
Status: NOT_YET_RECRUITING
Conditions: COVID-19
Interventions: DRUG: SHEN211 Tablets|PROCEDURE: Placebo for SHEN211 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Data Collection of PillCamTM SB3 Capsule Endoscopy and Device-Assisted Enteroscopy Routine Care Procedures (GPS Study)
Status: WITHDRAWN
Conditions: Small Intestine Disease|Small Intestine Cancer|Small Intestinal Ulcer Bleeding|Small Intestine Obstruction|Small Intestine Adenocarcinoma|Small Intestine Polyp
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or Carcinosarcoma
Status: UNKNOWN
Conditions: PD-1 Immunotherapy|VEGFR-TKI|Sarcomatoid Carcinoma|Carcinosarcoma
Interventions: DRUG: Camrelizumab Combined With Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Probiotics on Central Nervous System Functions in Humans
Status: COMPLETED
Conditions: Social Stress
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo for antibiotic|DRUG: Antibiotic|DIETARY_SUPPLEMENT: Placebo for probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: School-based Intervention to Promote Physical Activity in Adolescents in Spain: the Promoting Physical Activity in Secondary School For Health Project
Status: COMPLETED
Conditions: Activity, Motor
Interventions: BEHAVIORAL: Physical activity changes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial to Assess Chelation Therapy in Critical Limb Ischemia
Status: RECRUITING
Conditions: Critical Limb Ischemia|Diabetes
Interventions: DRUG: Edetate Disodium|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Versus Ketorolac For Postoperative Pain Relief After Cesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Ibuprofen 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Trial of Peptide T: Efficacy for the Neuropsychiatric Complications of Acquired Immunodeficiency Syndrome (AIDS).
Status: COMPLETED
Conditions: HIV Infections|Cognition Disorders
Interventions: DRUG: Peptide T
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT