pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bone Level Tapered Multi-Center Study
Status: UNKNOWN
Conditions: Tooth Loss
Interventions: DEVICE: Straumann Bone Level Tapered Implant - Immediate Placement|DEVICE: Straumann Bone Level Tapered Implant - Delayed Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Stem Cells for Diabetic Foot Ulcer
Status: NOT_YET_RECRUITING
Conditions: Diabetic Foot Ulcer
Interventions: DRUG: Allogeneic mesenchymal stem cells (MSCs)|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of BEPREVE 1.5% on Tear Film Osmolarity and Tear Film Lipid Layer
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Refresh Tears 0.5% Lubricant Eye Drops|DRUG: Bepreve 1.5% Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Post-market Study Evaluating Clinical and Radiographic Outcomes of Total Elbow Arthroplasty With TEMA
Status: NOT_YET_RECRUITING
Conditions: Total Elbow Arthroplasty
Interventions: DEVICE: TEMA elbow system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacokinetics and Absolute Bioavailability of GSK962040 Given as an Oral Dose Simultaneously With an Intravenous Microtracer Dose of [14C]-GSK962040 in Healthy Volunteers
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: A|DRUG: B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mindfulness Based Intervention as a Key Component of Successful Workplace Functioning and Personal Well-being
Status: UNKNOWN
Conditions: Emotional Stress|Work Related Illnesses|Burnout, Professional|Burnout Syndrome
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Wound Infiltration With Sodium Diclofenac vs Bupivacaine for Postoperative Pain Following Appendectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Bupivacaine|DRUG: Sodium diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Relative Bioavailability Study of Griseofulvin 125 mg/5 mL Suspension Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Griseofulvin 125 mg/5 mL Suspension, single dose|DRUG: Grifulvin V® 125 mg/5 mL Suspension, single dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: The Correlations Between HPV L1-Specific Immunologic Responses in Cervical Cancer and Cervical Intraepithelial Neoplasia (CIN) Patients and Their Prognosis
Status: UNKNOWN
Conditions: Cervical Cancer|Cervical Intraepithelial Neoplasia
Interventions: PROCEDURE: peripheral blood isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Dose-finding, Safety and Efficacy Study of NV1FGF in Patients With Intermittent Claudication
Status: COMPLETED
Conditions: Peripheral Arterial Occlusive Disease
Interventions: DRUG: XRP0038 (NV1FGF)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms
Status: NOT_YET_RECRUITING
Conditions: Colonic Neoplasms|Colonic Polyp|Diagnosis
Interventions: DEVICE: The system based on real - time artificial intelligence - assisted for colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Self-Management Using Smartphone Application for Type2 DM in Real siTuation (SMART-DM)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Self-Management Using Smartphone Application for Type2 DM|OTHER: self-management using booklet for management type 2 DM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Specifying and Treating Anxiety in Autism Research
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Anxiety
Interventions: DRUG: Sertraline|BEHAVIORAL: CBT/BIACA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CCR5-modified CD4+ T Cells for HIV Infection
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: SB-728-T|BIOLOGICAL: Expanded unmodified autologous CD4+ T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Bifidobacterium Breve Bif195 for Diarrhea-predominant Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Bifidobacterium breve Bif195|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs in Adults With Hepatitis C Virus Infection, Who Are Either Treatment-naive or Treatment-experienced in Brazil
Status: COMPLETED
Conditions: Chronic Hepatitis C Infection
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir and dasabuvir|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Self-Monitoring in Weight Loss With Technology
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: BEHAVIORAL: Standard behavioral treatment (SBT) for weight loss|BEHAVIORAL: SBT for weight loss using a PDA|BEHAVIORAL: SBT for weight loss using a PDA with feedback messages
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Efficacy and Quality of Life of Three Bleaching Products
Status: UNKNOWN
Conditions: Tooth Bleaching|Quality of Life
Interventions: OTHER: Dental bleaching with PaintOn Plus VivaStyle|OTHER: Dental Bleaching impact in quality of life with PaintOn Plus Vivastyle|OTHER: Dental bleaching with Opalescence GO|OTHER: Dental Bleaching impact in quality of life with Opalescence GO|OTHER: Dental bleaching with Opalescence PF|OTHER: Dental Bleaching impact in quality of life with Opalescence PF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnotherapeutic Olfactory Conditioning for Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Hypnotherapeutic Olfactory Conditioning (HOC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.
Status: UNKNOWN
Conditions: Radiation Injuries|Cognitive Impairment
Interventions: DRUG: Donepezil Hydrochloride|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Cost-effectiveness of Doin (Conduction Exercise) for Chronic Neck Pain
Status: COMPLETED
Conditions: Chronic Neck Pain
Interventions: PROCEDURE: Doin (conduction exercise)|DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma
Status: COMPLETED
Conditions: Hypertension, Glaucoma, Open-Angle
Interventions: DRUG: Placebo|DRUG: RO5093151
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ASP5354 in Healthy Adult Japanese Male Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Pudexacianinium chloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Interactive Augmented Reality and Electrical Neuromodulation System in Persons With Stroke
Status: RECRUITING
Conditions: Stroke
Interventions: BEHAVIORAL: Augmented Reality with Functional Electrical Stimulation group|BEHAVIORAL: Traditional physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: 1.25 mg/kg BL-8040 + BL-8040-matching placebo|DRUG: 2 mg/kg BL-8040|DRUG: BL-8040-matching placebo|DRUG: 400 mg Moxifloxacin (1x400 mg tablet)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Intermittent Preventive Treatment of Malaria in Schoolchildren
Status: COMPLETED
Conditions: Malaria|Intermittent Preventive Treatment
Interventions: DRUG: sulfadoxine-pyrimethamine|DRUG: amodiaquine + sulfadoxine-pyrimethamine|DRUG: dihydroartemisinin-piperaquine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pairing Psilocybin With Transcutaneous Auricular Vagus Nerve Stimulation
Status: NOT_YET_RECRUITING
Conditions: Healthy|Psychedelic Experiences|Vagus Nerve Stimulation
Interventions: DRUG: Psilocybin|DEVICE: Transcutaneous auricular Vagus Nerve Stimulation (taVNS)|DEVICE: Sham taVNS|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Effects of Ankaferd Blood Stopper
Status: ENROLLING_BY_INVITATION
Conditions: Colon Cancer|Oral Mucositis|Nurse's Role|Chemotherapy Effect
Interventions: COMBINATION_PRODUCT: Ankaferd Blood Stopper|OTHER: Bicarbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Effect of Aerobic Training and Moringa Oleifera on Dyslipidemia and Cardiac Endurance
Status: UNKNOWN
Conditions: Dyslipidemias
Interventions: OTHER: Aerobic training and Moringa Oleifera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of the ACYW135 Meningococcal Polysaccharide Conjugate Vaccine
Status: NOT_YET_RECRUITING
Conditions: Meningococcal Meningitis
Interventions: BIOLOGICAL: ACYW135 Meningococcal Polysaccharide Conjugate Vaccine|BIOLOGICAL: ACYW135 Meningococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of ILB in Patients With Amyotrophic Lateral Sclerosis
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: ILB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive|Lung Diseases, Obstructive|Asthma|COPD
Interventions: DEVICE: Point-of-Care Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Immunogenicity of Two Doses, Administered Three Weeks Apart, of Two Monovalent H5N1 Influenza Vaccines Containing 2 Doses of H5N1 Influenza Antigen, in Non-elderly Adult and Elderly Subjects
Status: COMPLETED
Conditions: Pandemic H5N1 Influenza
Interventions: BIOLOGICAL: H5N1 pandemic Influenza vaccine 3.75µg|BIOLOGICAL: H5N1 pandemic Influenza vaccine 7.5µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Jumping Exercises Approach in Individuals With Chronic Ankle Instability
Status: TERMINATED
Conditions: Joint Instability|Chronic Disease|Sprains
Interventions: OTHER: Jumping exercise|OTHER: Strength exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Advanced Stage III-IV Melanoma
Status: TERMINATED
Conditions: Recurrent Melanoma|Stage IIIB Skin Melanoma|Stage IIIC Skin Melanoma|Stage IV Skin Melanoma
Interventions: BIOLOGICAL: Recombinant Human Hsp110-gp100 Chaperone Complex Vaccine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma
Status: RECRUITING
Conditions: Pancreatic Cancer|Adenocarcinoma of the Pancreas|Adenocarcinoma
Interventions: DRUG: Motixafortide|DRUG: Cemiplimab|DRUG: Gemcitabine|DRUG: Nab paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults
Status: RECRUITING
Conditions: Obesity|Multiple Chronic Conditions
Interventions: OTHER: Prescriptive|BEHAVIORAL: Behavioral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition
Status: COMPLETED
Conditions: Wasting|Moderate Acute Malnutrition
Interventions: DIETARY_SUPPLEMENT: A daily ration of 40 kcal/kg of body weight during 56 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of HuMax-CD4, a New Drug to Treat Early Stage T-Cell Lymphoma in the Skin.
Status: COMPLETED
Conditions: Cutaneous T-Cell Lymphoma
Interventions: DRUG: HuMax-CD4|DRUG: HuMax-CD4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FOLFOXIRI With or Without Panitumumab in Metastatic Colorectal Cancer (VOLFI)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: FOLFOXIRI + Panitumumab|DRUG: FOLFOXIRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Lower Limb Strength Training Program on a Seated Robotic Device in Patients
Status: TERMINATED
Conditions: Stroke
Interventions: DEVICE: Group of strength training|OTHER: Group of physiotherapy not focus on strength training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Body Composition in Patients Treated by Adjuvant Hormonal Therapy for Breast Cancer (MetaCa2)
Status: COMPLETED
Conditions: Hormonal Therapy|Breast Cancer
Interventions: OTHER: Body composition measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Personalized Innovative Intervention Pathways to Promote EF in Children With CP
Status: NOT_YET_RECRUITING
Conditions: Executive Functions in Cerebral Palsy
Interventions: OTHER: Self-adaption web-based software for the rehabilitation of EF and visuo-spatial abilities|OTHER: Tele-rehabilitation of EF and specific cognitive processes underlying academic skills|OTHER: Game-based tools for the rehabilitation of EF and motor planning
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Pulmonary Rehabilitation on Bone Mineral Density in Patients Diagnosed With Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: BEHAVIORAL: Pulmonary Rehabilitation|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Study of Light Therapy on Depressive Episodes of Bipolar Disorder
Status: COMPLETED
Conditions: Depressive Episodes of Bipolar Disorder
Interventions: DEVICE: Bright Light therapy|DEVICE: dim Red Light therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intravenous and Subcutaneous Administration of IGIV, 10% in Primary Immunodeficiency (PID) Subjects
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: DRUG: Immune Globulin Intravenous (Human), 10%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open Study of the Safety, Tolerability and Immunogenicity of the Drug "Gam-COVID-Vac" Vaccine Against COVID-19
Status: COMPLETED
Conditions: Preventive Immunization COVID-19
Interventions: BIOLOGICAL: Gam-COVID-Vac
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Micro-stream Capnography in Non-intubated Lean and Obese Patients With and Without Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Obesity|Obstructive Sleep Apnea
Interventions: DEVICE: Microcapmicro-stream device with Smart CapnoLine Plus|DEVICE: Microcap micro-stream device with CapnoLine|DEVICE: TG-920 main-stream device (Nihon Kohden, Tokyo, Japan).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: PMCF Study to Evaluate Performance and Safety of "NASAL SPRAYS " Used to Relieve Nasal Congestion and Dryness
Status: COMPLETED
Conditions: Nasal Congestion|Nasal Dryness
Interventions: DEVICE: Nasal sprays with sea salts
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Ensifentrine or Placebo Delivered Via pMDI in Hospitalized Patients With COVID-19
Status: COMPLETED
Conditions: Coronavirus Infection|Covid-19|SARS-CoV-2
Interventions: DRUG: Ensifentrine Dose 1|DRUG: Placebo pMDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Prospective Study of Two Methods of Revascularization of the Femoral Artery (SFA): Stenting in the SFA, and Stenting of the SFA, Supplemented by Fasciotomy in Hunter Channel.
Status: UNKNOWN
Conditions: Atherosclerosis of the Peripheral Artery
Interventions: PROCEDURE: Angioplasty with stenting of the femoral artery|PROCEDURE: Angioplasty with stenting of the femoral artery, supplemented by fasciotomy in Hunter's channel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Pharmacokinetic Characteristics of AD-102 in Healthy Volunteers
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Raloxifene 60mg/Cholecalciferol 800IU|DRUG: AD-102
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DIalectical Behavior Therapy and Acceptance Commitment Therapy Short Program for BOrderLine persOnality Disorder
Status: WITHDRAWN
Conditions: Female|Borderline Personality Disorder
Interventions: BEHAVIORAL: DBT+ACT|BEHAVIORAL: DBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Assess the Effect on Recovery of GI Motility and Safety and to Determine the Optimal Dose of LD02GIFRO
Status: COMPLETED
Conditions: Colon Resection|_large Interstinal Surgery
Interventions: DRUG: LD02GIFRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity
Status: RECRUITING
Conditions: Cerebrovascular Function|Cognition
Interventions: OTHER: Placebo|DIETARY_SUPPLEMENT: β-OHB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: ULTRAsound-assisted Catheter vs. STAndaRd Catheter Thrombolysis for Submassive Pulmonary Embolism
Status: COMPLETED
Conditions: Submassive Pulmonary Embolism
Interventions: PROCEDURE: catheter-directed thrombolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tusamitamab Ravtansine in NSQ NSCLC Participants With Negative or Moderate CEACAM5 Expression Tumors and High Circulating CEA
Status: ACTIVE_NOT_RECRUITING
Conditions: Non-squamous Non-small Cell Lung Cancer
Interventions: DRUG: Tusamitamab ravtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Local and Intraperitoneal Analgetics in Gynecologic Laparoscopy for Post Operative Pain Relief
Status: UNKNOWN
Conditions: Postoperative Complications
Interventions: DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy of the Addition of 0.3% Lidocaine With EVOLENCE®
Status: COMPLETED
Conditions: Aging|Pain
Interventions: DEVICE: Evolence|DEVICE: Lidocaine|DRUG: topical anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: Blood sample|DIAGNOSTIC_TEST: CRQ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tailored Inhibitory Control Training to Reverse EA-linked Deficits in Mid-life
Status: COMPLETED
Conditions: Smoking|Alcohol Drinking|Prescription Drug Abuse|Substance-Related Disorders|Oral Intake Reduced
Interventions: BEHAVIORAL: Person-centered inhibitory control training|BEHAVIORAL: Active behavioral response training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
Status: RECRUITING
Conditions: Radiation Toxicity|Esophagitis|Esophageal Cancer
Interventions: DRUG: Deep-sea fish oil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean Section
Status: RECRUITING
Conditions: Misoprostol Allergy
Interventions: DRUG: Misoprostol 200mcg Tab|DRUG: Misoprostol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Assess the Absorption, Metabolism, Excretion and Pharmacokinetics of [14C]-AKB-9778
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: AKB-9778 subcutaneous injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability
Status: COMPLETED
Conditions: Ankle Sprain|Ankle Injuries|Sprain
Interventions: OTHER: proximal tibiofibular manipulation|OTHER: distal tibiofibular manipulation|OTHER: no intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Molecular Weight Hyaluronic Acid, α-lipoic Acid, Magnesium, Vitamin B6 and Vitamin D, in the Prevention of Spontaneous Abortion
Status: COMPLETED
Conditions: Abortion, Spontaneous
Interventions: OTHER: high molecular weight hyaluronic acid, α-lipoic acid (ALA), magnesium, vitamin B6 and vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Clinical Trial of BP1002 in Patients With Refractory/Relapsed Acute Myeloid Leukemia (AML)
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, in Relapse|Acute Myeloid Leukemia Refractory
Interventions: DRUG: BP1002; Liposomal Bcl-2 Antisense Oligodeoxynucleotide|DRUG: Decitabine (in combination with BP1002)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deferred Cytoreductive Nephrectomy in Synchronous Metastatic Renal Cell Carcinoma: The NORDIC-SUN-Trial
Status: RECRUITING
Conditions: Kidney Cancer|Renal Cell Carcinoma Metastatic|Synchronous Neoplasm
Interventions: PROCEDURE: Cytoreductive nephrectomy|OTHER: Tissue sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Subacute Effects of Spinal Mobilization to Treat Subacromial Impingement
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: OTHER: thoracic mobilization & shoulder mobilization & exercise|OTHER: shoulder mobilization & exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression
Status: COMPLETED
Conditions: Bipolar Depression
Interventions: DRUG: Esketamine DPI - low dose|DRUG: Esketamine DPI - medium dose|DRUG: Esketamine DPI - high dose|DRUG: Placebo DPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Application Value of Remazolam Combined With Sugammadex Sodium in Anesthesia for Endotracheal Surgery Under Bronchoscopy
Status: COMPLETED
Conditions: Endobronchial Metastases|Bronchoesophageal Fistula|General Anesthetic Drug Adverse Reaction
Interventions: DRUG: Remimazolam|DRUG: Propofol|DRUG: Rocuronium|DRUG: Remifentanil|DRUG: oxycodone|DRUG: Sugammadex Sodium|DRUG: Flumazenil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Constraint Induced Movement Therapy on Infantile Hemiplegia
Status: COMPLETED
Conditions: Hemiplegia
Interventions: PROCEDURE: mCIMT|PROCEDURE: Unimanual therapy without constraint UTWC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer Metastatic|Pancreatic Ductal Adenocarcinoma|Pancreatic Cancer Stage IV
Interventions: DRUG: SBP-101|DRUG: Nab-paclitaxel|DRUG: Gemcitabine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ribavirin Loading Dose or Priming and Concentration Targeting for HCV Genotype 1
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: Ribavirin "loading" dose given|DRUG: "Priming" dose of ribavirin given|DRUG: Group C ("Standard-of-Care")
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating TESLA-G, a Gamified, Telegram-delivered, Quizzing Platform for Surgical Education in Medical Students
Status: NOT_YET_RECRUITING
Conditions: Surgical Education in Medical Students
Interventions: OTHER: Gamified online quizzing platform|OTHER: Conventional quizzing platform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Colorectal Omics and ofCS Proteoglycans
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Diverticulitis, Colonic|Inflammatory Bowel Diseases|Stoma Colostomy
Interventions: PROCEDURE: Colorectal resection or stoma closure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine
Status: COMPLETED
Conditions: Solid Tumours
Interventions: DRUG: Savolitinib|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lacosamide in Preventing Seizures in Participants With Malignant Glioma
Status: TERMINATED
Conditions: Malignant Glioma
Interventions: DRUG: Lacosamide|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Manual Acupuncture Using Acupuncture Needle vs Press Needle for COVID-19 Healthcare Anxiety
Status: COMPLETED
Conditions: Anxiety
Interventions: PROCEDURE: Manual Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Injection Site Diversity Influences HA Distribution and Clinical Results in CP and KOA
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Hyaluronan
Interventions: PROCEDURE: medial midpatellar (MMP) portal|PROCEDURE: anteromedial (AM) portal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Vildagliptin Compared to Placebo on the Incretin Effect in Patients With Type 2 Diabetes Treated With Metformin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: vildagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: PRF in Management of Chronic Multiple Oral Ulcers
Status: COMPLETED
Conditions: Oral Ulcer Due to Pemphius Vularis|Oral Ulcer Due to Benign Mucous Membrane Pemphioid|Oral Ulcer Due to Steven Johnson's Syndrome
Interventions: BIOLOGICAL: Platelet rich fibrin gel in Orabase|DRUG: Dermovate cream in Orabase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Chewing Gums Versus Laxative in Early Return of Bowel Function After CS
Status: UNKNOWN
Conditions: Intestinal Recovery After Cesarean Section
Interventions: OTHER: gums|DRUG: picolax drops|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Azacitidine Plus Phenylbutyrate in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Diseases
Interventions: DRUG: azacitidine|DRUG: sodium phenylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)
Interventions: DRUG: Gefitinib|DRUG: AZD9291|DRUG: Selumetinib+Docetaxel|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients
Status: COMPLETED
Conditions: Hemodialysis|Restless Legs Syndrome|ESRD (End Stage Renal Disease)|Diabetes Complications
Interventions: DRUG: Dopamine Agonist (Ropinirole)|OTHER: Excercise training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: External Drainage Versus Internal Drainage of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD)
Status: UNKNOWN
Conditions: Postoperative Fistula|Complications of Surgical and Medical Care: General Terms
Interventions: PROCEDURE: Internal Drainage of Pancreatic Duct after pancreatomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
Status: TERMINATED
Conditions: Obstetric Labour, Premature
Interventions: DRUG: Retosiban|DRUG: Atosiban|DRUG: Placebo matching retosiban|DRUG: Placebo matching atosiban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Cysview|DEVICE: Karl Storz D-Light C Photodynamic Diagnostic (PDD) system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Eccentric Training for Shoulder Abductors in Subjects With Shoulder Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: DEVICE: Isokinetic eccentric training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasability of Foot Reflexology to Alleviate Anxiety in Palliative Care Unit (RPASP)
Status: UNKNOWN
Conditions: End Stage Disease
Interventions: OTHER: foot reflexology|OTHER: toucher massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevalence and Risk Factors of Women Mental Health Disorders
Status: UNKNOWN
Conditions: Psychiatric Problem|Wolman Disease
Interventions: BEHAVIORAL: Sociodemographic variables|BEHAVIORAL: Family affluence scale (FAS)|BEHAVIORAL: Edinburgh postnatal depression scale (EPDS)|BEHAVIORAL: Symptom Checklist 90 "SCL 90":
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
Status: COMPLETED
Conditions: Cesarean Section Complications|Postpartum Hemorrhage|Blood Loss, Surgical|Blood Loss, Postoperative|Postoperative Pain|Atony, Uterine
Interventions: OTHER: before uterine incision oxytocin|OTHER: after clamping the umbilical cord oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive ONSD-based Neuromonitoring in a Neurointensive Care Setting
Status: NOT_YET_RECRUITING
Conditions: Trauma, Brain|Subarachnoid Hemorrhage|Intracranial Hypertension
Interventions: DIAGNOSTIC_TEST: Sonographic determination of the optic nerve sheath diameter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Mobile Enhancement of Motivation in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizo Affective Disorder|Psychosis
Interventions: BEHAVIORAL: Mobile Enhancement of Motivation (MEMS)|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Pirfenidone in Acute Pancreatitis
Status: RECRUITING
Conditions: Pancreatitis, Acute
Interventions: DRUG: Pirfenidone Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of MD-120 in Patients With Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Desvenlafaxine 100 mg|DRUG: Desvenlafaxine 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine for Neoadjuvant Therapy of Gastric Adenocarcinoma/Gastroesophageal Junction Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: SHR-1210 Combined With Trastuzumab , Oxaliplatin and Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hope Soap Study: a Hand-washing Intervention Among Children in South Africa
Status: COMPLETED
Conditions: Hand-washing Behavior|Diarrhea
Interventions: COMBINATION_PRODUCT: Hope Soap|COMBINATION_PRODUCT: Control group soap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: Bevacizumab|DRUG: Temsirolimus|DRUG: Bevacizumab|DRUG: Interferon-Alfa 9MU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Deep Extubation During Emergence Using Desflurane or Desflurane With Remifentanil in Patients Undergoing General Anesthesia
Status: COMPLETED
Conditions: Deep Extubation
Interventions: DRUG: Desflurane with remifentanil|DRUG: Desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of the Noradrenergic System on the Formation of Intrusive Memories
Status: COMPLETED
Conditions: Intrusive Memories
Interventions: BEHAVIORAL: Stress Film|DRUG: Yohimbine|DRUG: Clonidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety, Pharmacokinetics, and Clinical Effects of Cinacalcet (AMG 073) in Primary Hyperparathyroidism
Status: COMPLETED
Conditions: Primary Hyperparathyroidism
Interventions: DRUG: Cinacalcet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Status: COMPLETED
Conditions: Traumatic Brain Injury|Stroke
Interventions: DEVICE: MyoPro Motion-G|OTHER: Motor Learning-Based Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination of Ten Elements for 6 Months in Patients With Diabetic Neuropathy : A Pilot Study
Status: COMPLETED
Conditions: Diabetic Neuropathies|Diabetes Mellitus|Dietary Supplement
Interventions: DIETARY_SUPPLEMENT: Epineuron|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Treatment With Atorvastatin for Episodic Migraine.
Status: RECRUITING
Conditions: Episodic Migraine
Interventions: DRUG: Atorvastatin 40mg|DRUG: Placebo|DRUG: Atorvastatin 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Enhanced External Counterpulsation (EECP) on VO2 MAX
Status: WITHDRAWN
Conditions: Cardiovascular Disease|Pulmonary Disease
Interventions: DEVICE: Enhanced External Counterpulsation (EECP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Leiomyosarcoma
Status: RECRUITING
Conditions: Leiomyosarcoma
Interventions: DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Mid-thoracic Manipulation on Heart Rate Variability.
Status: UNKNOWN
Conditions: Neurophysiological Mechanisms Underlying Spinal Manipulation
Interventions: OTHER: Experimental Group|OTHER: Sham Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: the Food Effect Pharmacokinetic, Material Balance and Metabolite Identification of SP2086 in Healthy Volunteers
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DRUG: SP2086|DIETARY_SUPPLEMENT: high fat diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin for Reducing Inflammation and Immune Activation
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Sitagliptin|DRUG: Placebo for sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Cantrixil in Patients With Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer.
Status: COMPLETED
Conditions: Ovarian Neoplasms|Fallopian Tube Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: Part A: Dose Escalation of Cantrixil|DRUG: Part B: Expansion Cohort of Cantrixil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transfusion of Red Blood Cells, Tranexamic Acid and Fibrinogen Concentrate for Severe Trauma Hemorrhage
Status: COMPLETED
Conditions: Hemorrhagic Shock
Interventions: DRUG: with red blood cells (RBC), Tranexamic acid (TXA) and Fibrinogen Concentrate (FC),administration of Crystalloids and TXA.|DRUG: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids
Status: RECRUITING
Conditions: Type 2 Diabetes|Inflammation|Insulin Sensitivity/Resistance|Fatty Acids, Omega-3
Interventions: DIETARY_SUPPLEMENT: Omega-3 fatty acids
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Sotagliflozin (SAR439954)|DRUG: Glimepiride|DRUG: Metformin|DRUG: Placebo|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Controlled, Open-label Clinical Trial of Adjuvant Intensive Therapy for HR+/ HER2-SNF4 Early Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: HR+/HER2-breast Cancer
Interventions: DRUG: Standard endocrine therapy plus Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT