pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Nipple Aspirate Fluid in Detecting Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Anatomic Stage IV Breast Cancer AJCC v8|Estrogen Receptor Negative|Healthy Subject|HER2 Positive Breast Carcinoma|HER2/Neu Negative|Luminal A Breast Carcinoma|Luminal B Breast Carcinoma|Progesterone Receptor Negative|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage IV Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: PROCEDURE: Aspiration of Breast|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Pain Neuroscience Education (PNE) to Veterans With Post-Traumatic Stress and Low Back Pain
Status: COMPLETED
Conditions: Chronic Low Back Pain|Post-traumatic Stress
Interventions: BEHAVIORAL: Pain Neuroscience Education|BEHAVIORAL: Exercise|BEHAVIORAL: Traditional Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RDC-Blinatumomab Versus hyperCVAD for Ph-negative B-ALL.
Status: RECRUITING
Conditions: ALL, Adult|Philadelphia-Negative ALL
Interventions: DRUG: Blinatumomab Injection [Blincyto]|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bromelain and Cardiovascular Risk Factors in Diabetes
Status: COMPLETED
Conditions: Cardiovascular Disease.
Interventions: DIETARY_SUPPLEMENT: bromelain capsule|DIETARY_SUPPLEMENT: placebo (wheat starch)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Characterization of Left Atrial Substrate by Comparison of Bipolar Voltage Maps With Standard Focal 4.5 mm Tip Electrode, 1 mm Ring Electrode, and Microelectrode Catheters Using InTEllaMap Orion and IntellaNav MIFI O
Status: COMPLETED
Conditions: Atrial Fibrillation (AF)
Interventions: DIAGNOSTIC_TEST: multipolar mapping catheter|DIAGNOSTIC_TEST: multielectrode circular catheter|DIAGNOSTIC_TEST: irrigated ablation catheter
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism
Status: TERMINATED
Conditions: Cancer|Venous Thromboembolism|Obesity
Interventions: BIOLOGICAL: Dalteparin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fatty Acid Antiarrhythmia Trial (FAAT)
Status: COMPLETED
Conditions: Arrhythmia|Heart Diseases|Tachycardia, Ventricular|Ventricular Fibrillation
Interventions: BEHAVIORAL: dietary polyunsaturated fatty acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Cyanoacrylate Closure Versus Surgical Stripping for Incompetent Saphenous Veins
Status: UNKNOWN
Conditions: Occlusions Vein|Chronic Venous Insufficiency
Interventions: PROCEDURE: Cyanoacrylate closure|PROCEDURE: Surgical stripping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-Articular Platelet Rich Plasm Use in Osteoarthritis of Knee.
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: platelet rich plasm|DRUG: Triamcinolone Hexacetonide|PROCEDURE: Isotonic Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Parallel-group Study to Determine the Pharmacokinetics of a Single Dose of AFQ056 in Subjects With Renal Impairment Compared to Healthy Subjects
Status: COMPLETED
Conditions: Mild Moderate|or Severe Renal Impairment
Interventions: DRUG: AFQ056
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acetylcarnitine and Metabolic Flexibility
Status: COMPLETED
Conditions: Glucose Intolerance
Interventions: DIETARY_SUPPLEMENT: Carnitine supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Evaluate the Efficacy of ITDD vs. CMM in the Treatment of Pancreatic Cancer Pain
Status: WITHDRAWN
Conditions: Pain Management|Cancer Pain
Interventions: DEVICE: Intrathecal Drug Delivery System|OTHER: Conventional Medical Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Amdoxovir in HIV-1 Treatment-experienced Subjects.
Status: TERMINATED
Conditions: Human Immunodeficiency Virus Infection
Interventions: DRUG: amdoxovir 300 mg bid|DRUG: amdoxovir 500 mg bid|DRUG: tenofovir DF 300 mg qd
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Opioid-free Anesthesia on PostOperative Nausea and Vomiting in Patients Undergoing Video-assisted Thoracoscopic Surgery
Status: RECRUITING
Conditions: Postoperative Nausea and Vomiting|Opioid Use|Thoracic Diseases
Interventions: PROCEDURE: Opioid-Free Anesthesia (OFA)|PROCEDURE: Standard general anesthesia (OA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Evaluation of Propolis Mouthwash With 0.2% Chlorhexidine Mouthwash in Improving the Periodontitis
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: DRUG: Propolis mouthwash|DRUG: Chlorhexidine mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tele-Nursing Based Motivational Interviewing in Individuals With Type 2 Diabetes:RCT
Status: COMPLETED
Conditions: Type2 Diabetes|Self Efficacy|Self Management|Tele-nursing|Motivational Interview|LDL - Low Density Lipoprotein Receptor Disorder|High Density Lipoprotein Deficiency|Cholesterol; Lipidosis
Interventions: BEHAVIORAL: Tele-Nursing based Motivational Interviewing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Chronic Hand Eczema With Oral Roflumilast (HERO)
Status: RECRUITING
Conditions: Chronic Hand Eczema
Interventions: DRUG: Roflumilast 500 Mcg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pneumococcal Vaccination to Accelerate Immune Recovery in Sepsis Survivors
Status: COMPLETED
Conditions: Sepsis
Interventions: BIOLOGICAL: Prevenar 13|OTHER: Sodium Chloride 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment of Keratoconjunctivitis Sicca (Dry Eye Syndrome)
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca (KCS)
Interventions: DEVICE: KCS Medical Device|DEVICE: KCS Medical Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: AMG 557|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardioneuroablation for the Treatment of Vagally-mediated Atrial Fibrillation.
Status: COMPLETED
Conditions: Atrial Fibrillation Paroxysmal
Interventions: PROCEDURE: Cardioneuroablation (CNA) of the right anterior ganglionated plexus (RAGP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Kyphoplasty With Structured Titanium Spheres
Status: UNKNOWN
Conditions: Vertebral Fracture
Interventions: DEVICE: Kyphoplasty with insertion of Sctructured Titanium Microspheres|DEVICE: Kyphoplasty with Polimethylmetacrilate (convetional surgery)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Energy Intake and Energy Deficit in Obese Adolescents
Status: UNKNOWN
Conditions: Pediatric Obesity
Interventions: BEHAVIORAL: DEF-EI : Energy restriction induced energy deficit|BEHAVIORAL: DEF-EX : Exercise induced energy deficit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Collection of Performance Data From the Integrated Sensor and Infusion Set. TRIAL 4
Status: UNKNOWN
Conditions: Diabetes Mellitus Type I|Diabetes Mellitus Type II
Interventions: DEVICE: Integrated sensor and infusion set.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Femur Transtrochanteric Fractures Treated With Dynamic Hip Screw and Calcium Sulfate Scaffold.
Status: COMPLETED
Conditions: Proximal Femur Fracture
Interventions: DEVICE: Study group with absorbable graft of tricalcium ß phosphate / calcium sulfate hemihydrate paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neuroprotection With N-acetyl Cysteine for Patients With Progressive Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Multiple Sclerosis, Primary Progressive|Multiple Sclerosis, Secondary Progressive
Interventions: DRUG: N-acetyl cysteine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Patients Who Underwent Thyroid Ultrasonography at Our Institution Were Selected for Shear Wave Elastography of Thyroid Nodules, and the Maximum and Mean Values of the Modulus of Elasticity of the Nodules in Transverse and Longitudinal Sections Were Analyzed.
Status: COMPLETED
Conditions: Thyroid Nodules
Interventions: OTHER: section orientation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Single Arm, Phase II Exploratory Clinical Study of Pemitinib in Advanced Gastric Cancer With Previous Standard Therapy Failure the FGFR Variant
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Unresectable Gastric Cancer
Interventions: DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunomodulation of E.Coli Nissle 1917 in Patients With Grass Pollen Rhinoconjunctivitis
Status: COMPLETED
Conditions: Rhinoconjunctivitis
Interventions: DRUG: Mutaflor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Unintentional Weight Loss and Anorexia With GI Cancer
Status: COMPLETED
Conditions: Malignant Neoplasm of Gastrointestinal Tract
Interventions: DEVICE: Cachexia Acupuncture-A (Peace Classic Needles® )|DEVICE: General Acupuncture-B (Peace Classic Needles®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Subjective and Conjunctival Response to Edge Design of Different Silicone Hydrogels
Status: COMPLETED
Conditions: Contact Lenses
Interventions: DEVICE: Senofilcon A contact lens (Acuvue Oasys)|DEVICE: Comfilcon A contact lens (Biofinity)|DEVICE: Lotrafilcon B contact lens (Air Optix)|DEVICE: Balafilcon A contact lens (PureVision)|DEVICE: Etafilcon A contact lens (Acuvue 2)|DEVICE: Contact lens care system (EasySept)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Long Term Results of Combined Transpupillary Thermotherapy (TTT) Indocyanine Green (ICG) Based Photodynamic Therapy (PDT) in Choroidal Melanoma
Status: COMPLETED
Conditions: Choroidal Melanoma
Interventions: PROCEDURE: TTT + ICG-based PDT
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hospital Outcomes: Intervention in Moderately III Patients
Status: COMPLETED
Conditions: Moderately Ill Medical Inpatients at the Cornell Campus of the New York-Presbyterian Hospital
Interventions: BEHAVIORAL: Early assessment and referral to ancillary care services vs. standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of ECA on Quality of Life in Head and Neck Cancer Patients Suffering From Cetuximab-induced Rhagades
Status: UNKNOWN
Conditions: Pain
Interventions: DEVICE: ECA|OTHER: Standard topical treatment of the institution, e.g. Lotio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Double Lumen Tube Placement Techniques
Status: TERMINATED
Conditions: Airway Morbidity|Intubation Complication|Tracheal Intubation Morbidity|Anesthesia Intubation Complication|Failed or Difficult Intubation, Sequela
Interventions: DEVICE: ZU-bend stylet|DEVICE: GlideScope|DEVICE: GlideRite stylet|DEVICE: Macintosh blade|DEVICE: Regular Double-lumen endobronchial tube (DLT) Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects Of Food And Dose Regimen On The Antiviral Effects Of Maraviroc (UK-427,857) In Patients With Human Immunodeficiency Virus
Status: COMPLETED
Conditions: HIV
Interventions: DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|DRUG: Maraviroc (UK-427,857)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Anatomic Stage III Breast Cancer AJCC v8|Anatomic Stage IIIA Breast Cancer AJCC v8|Anatomic Stage IIIB Breast Cancer AJCC v8|Anatomic Stage IIIC Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Prognostic Stage III Breast Cancer AJCC v8|Prognostic Stage IIIA Breast Cancer AJCC v8|Prognostic Stage IIIB Breast Cancer AJCC v8|Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions: PROCEDURE: Discussion|OTHER: Exercise Intervention|OTHER: Exercise Intervention|OTHER: Informational Intervention|OTHER: Informational Intervention|OTHER: Medical Device Usage and Evaluation|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Home-based Neuromodulation to Target Depression And Memory Symptoms in Older Adults
Status: RECRUITING
Conditions: Major Depressive Disorder|Alzheimer Disease|Dementia|Nervous System Diseases|Memory Disorders|Depressive Disorder
Interventions: DEVICE: Transcranial direct current stimulation (tDCS); Transcranial alternating current stimulation (tACS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Heme/Non-heme Iron and Helicobacter Pylori (Hp) Infection on Maternal Iron-deficiency Anemia and Fetal Growth Outcomes
Status: UNKNOWN
Conditions: Pregnancy|Helicobacter Pylori Infection|Iron-Deficiency Anemia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Patients With Nocturia
Status: COMPLETED
Conditions: Nocturia
Interventions: DRUG: SER120|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Buspirone for Relapse-Prevention in Adults With Cocaine Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Buspirone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Intervention in Children With Autism Using Whey Protein (Immunocal): Impact on Core Areas of Behavior
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Rice Protein (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: IMAGE: A Comparison of AlloMap Molecular Testing and Traditional Biopsy-based Surveillance for Heart Transplant Rejection
Status: COMPLETED
Conditions: Graft Rejection|Heart Diseases
Interventions: DEVICE: AlloMap molecular expression testing|PROCEDURE: Right ventricular endomyocardial biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Use of Neurostimulation as a Tool for Reconditioning the Neuromuscular System of Patients Admitted to the ICU for Septic Shock
Status: RECRUITING
Conditions: Septic Shock
Interventions: OTHER: Usual care|OTHER: Electrostimulation|OTHER: Evaluation of the neuromuscular system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ad26.COV2.S as a Heterologous Booster in Adults After Single- or Two-Dose of Inactivated COVID-19 Vaccine
Status: RECRUITING
Conditions: SARS-CoV-2 Infection
Interventions: BIOLOGICAL: Full dose of Ad26.COV2. 5x10^10vp|BIOLOGICAL: Half dose of Ad26.COV2. 2.5x10^10vp|BIOLOGICAL: Full dose of Ad26.COV2. 5x10^10vp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clonidine as Pain Relief During ROP Eye Examinations
Status: RECRUITING
Conditions: Retinopathy of Prematurity|Pain, Procedural|Premature Infant Disease
Interventions: DRUG: Clonidine Oral Liquid Product|DRUG: Sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERD
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: Esomeprazole|DRUG: esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Chronic Myelogenous Leukemia|Acute Myelogenous Leukemia|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Myelodysplastic Syndrome
Interventions: BIOLOGICAL: VCL-CB01|OTHER: Phosphate-buffered Saline (PBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Absorption & Elimination of Radiolabelled GSK2269557
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: [14C]-GSK2269557 IV infusion|DRUG: GSK2269557 via DPI|DRUG: [14C]-GSK2269557 oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Aclidinium Bromide 200 µg|DRUG: Aclidinium Bromide 400 µg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of 12-week Probiotic Consumption Immobilized on Oat Flakes on Blood and Urine Biomarkers and Human Microbiome
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Probiotic oat flakes|OTHER: Conventional oat flakes
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: trospium chloride inhalation powder (TrIP)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol
Status: COMPLETED
Conditions: Hydrocephalus|Shunt Malfunction
Interventions: DEVICE: Tympanic Membrane Displacement (TMD)|DEVICE: DPOAE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Platelet-rich Plasma in the Surgery of Carpal Tunnel Syndrome: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: PROCEDURE: Platelet-rich plasma|PROCEDURE: Platelet-poor plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein
Status: COMPLETED
Conditions: Venous Disease
Interventions: DEVICE: Compression Stockings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Bi-homonal Bionic Pancreas|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Dysmotility on Aspiration Risk
Status: NOT_YET_RECRUITING
Conditions: Esophageal Motility Disorders|Gastric Motor Dysfunction|Aspiration Pneumonia|Gastro Esophageal Reflux
Interventions: DRUG: Prucalopride|DRUG: Famotidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Modeling TMS-induced Cortical Network Activity
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: DEVICE: Session 2: Single-pulse TMS (spTMS)|DEVICE: Sessions 3 - 5: Paired associative stimulation (PAS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: NEO Rehab Program for Premature Infants at Risk for Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy|Prematurity|Early Intervention|Family Centered Care
Interventions: OTHER: NeoRehab Bundle|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eslicarbazepine Acetate as Preventive Therapy for Subjects With Migraine
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Placebo|DRUG: ESL 1200 mg|DRUG: ESL 800 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial
Status: UNKNOWN
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: Dexamethasone|DRUG: Normal saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With Low-Dose Ribavirin QD in Subjects With Genotype 1a Chronic Hepatitis C Virus Infection
Status: COMPLETED
Conditions: Hepatitis C Virus (HCV)
Interventions: DRUG: ombitasvir/paritaprevir/ritonavir and dasabuvir|DRUG: ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acute Hemodynamic Effect of Acetazolamide in Pulmonary Hypertension
Status: COMPLETED
Conditions: Hypertension, Pulmonary
Interventions: DRUG: Acetazolamide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Knee Pain With Topical Diclofenac Cream 8% or Diclofenac Gel 1%
Status: UNKNOWN
Conditions: Knee Pain Chronic|Knee Injuries
Interventions: DRUG: Diclofenac Cream 8%|DRUG: Diclofenac Gel 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of CoCr Alloy and TiN Coating in TKA
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee|Arthroplasty, Replacement, Knee
Interventions: DEVICE: TiN-alloy based total knee arthroplasty|DEVICE: CoCr-coating based total knee arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on the Using a Newer Computed Tomography (CT) Based Technique for the Detection of Altered Bowel Blood Flow Among Patients Suffering From Chronic Mesenteric Ischemia During Meal Digestion.
Status: UNKNOWN
Conditions: Bowel; Ischemic, Chronic|Tomography, X-Ray Computed|Dual-energy CT
Interventions: DIAGNOSTIC_TEST: Dual-energy CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Combination Chemotherapy in Treating Patients With Germ Cell Tumors That Have Not Responded to Previous Cisplatin
Status: COMPLETED
Conditions: Ovarian Cancer|Testicular Germ Cell Tumor
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: ifosfamide|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Multidisciplinary Approach to Reduce Injury and Substance Abuse
Status: COMPLETED
Conditions: Drug Abuse
Interventions: BEHAVIORAL: Brief advice|BEHAVIORAL: Brief Intervention plus Booster|BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)
Status: RECRUITING
Conditions: Schizophrenia and Related Disorders
Interventions: BEHAVIORAL: Cognitive Enhancement Therapy|BEHAVIORAL: Social Skills Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Anti-diabetic Drugs on Glycemic Variability
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Dapagliflozin|DRUG: Gliclazide MR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Articular Solutions With Intraosseous and Synovial Platelet-Rich Plasma
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: COMBINATION_PRODUCT: Platelet rich-plasma - PRP - intraosseous and intra-articular admnistration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An OCT-Guided Variable Dosing Regimen With Ranibizumab for the Treatment of Neovascular AMD
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: Ranibizumab (Lucentis)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salpingectomy vs Tubal Sterilisation in Low Risk for Ovarian Cancer Women and Its Effect on Ovarian Reserve
Status: UNKNOWN
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Bilateral Salpingectomy|PROCEDURE: Tubal sterilization with bipolar energy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Monotherapy Versus Placebo Over 14 or 17 Days in Healthy and Hepatitis C Infected Adults
Status: TERMINATED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: DRUG: GSK625433/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Biomarker-based Multidisciplinary Team (Bio-MDT) Approach to Personalized Microbial-targeted Treatment of Pouchitis and Crohn's Disease
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases
Interventions: OTHER: Arm 1- Antibiotics treatment|OTHER: Arm 2- Antibiotics treatment|OTHER: Arm 1- Combination therapy (Antibiotics + diet)|OTHER: Arm 2- Combination therapy (Antibiotics + diet)|OTHER: Arm 1- Nutritional prevention|OTHER: Arm 2- Nutritional prevention|OTHER: Arm 3- Nutritional prevention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Azacitidine and Lenalidomide for Relapsed and Refractory Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Azacitidine|DRUG: Lenalidomide|OTHER: Off Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Substitution of Sulfonylureas With New Generation of Hypoglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: T2DM (Type 2 Diabetes Mellitus)|Diet, Healthy|Renal Function Disorder|Albuminuria
Interventions: DRUG: Sulfa-zero: possible benefits of the treatment of new generation hypoglycaemic drugs compared to sulphonylureas
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Repair of Thoracoabdominal Aortic Aneurysms
Status: RECRUITING
Conditions: Thoracoabdominal Aneurysm
Interventions: DEVICE: Medtronic Valiant Thoracoabdominal Stent Graft System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Use of Vasopressin as a Primary Vasoconstrictor in Critically Ill Patients
Status: RECRUITING
Conditions: Circulatory Shock
Interventions: DRUG: Initiation of vasopressine as a first vasoconstrictive drug|DRUG: Initiation of noradrenaline as a first vasoconstrictive drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acceptance and Commitment Therapy for Patients With Chronic Heart Failure and Their Caregivers on Their Quality of Life
Status: COMPLETED
Conditions: Chronic Heart Failure
Interventions: BEHAVIORAL: ACT (Acceptance and Commitment Therapy) plus brief CHF education|BEHAVIORAL: HE (Health Education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Antiviral Activity Study of ACH-126,443 (Beta-L-Fd4C) in Treatment-naive Adults With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: ACH-126,443|DRUG: Lamivudine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lobaplatin/Etoposide With or Without Anlotinib Maintenance Therapy in Patients With ES-SCLC
Status: UNKNOWN
Conditions: Small Cell Lung Carcinoma
Interventions: DRUG: Anlotinib Hydrochloride|DRUG: Lobaplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Praziquantel Versus Artesunate + Sulfamethoxypyrazine/Pyrimethamine for Treating Schistosomiasis
Status: COMPLETED
Conditions: Schistosoma Haematobium
Interventions: DRUG: Artesunate+Sulfamethoxypyrazine/pyrimethamin|DRUG: Praziquantel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Prebiotic Effect on Metabolites in Crohn's Disease
Status: COMPLETED
Conditions: Crohn Disease
Interventions: DIETARY_SUPPLEMENT: Oligofructose enriched inulin|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Treatments for Benign Paroxysmal Positional Vertigo (BPPV)
Status: COMPLETED
Conditions: Vertigo
Interventions: BEHAVIORAL: Canalith repositioning maneuver (Epley maneuver)|BEHAVIORAL: Semont maneuver|BEHAVIORAL: Brandt-Daroff exercises|BEHAVIORAL: Vestibular habituation exercises|BEHAVIORAL: ShamManeuver
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DIAGNOSTIC_TEST: 18F-DOPA with furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Creatine Supplementation in Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer|Chemotherapy Effect|Muscle Weakness|Muscle Loss|Exercise
Interventions: DIETARY_SUPPLEMENT: Creatine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of LY573636-sodium in Essential Thrombocythemia and Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Essential Thrombocythemia
Interventions: DRUG: LY573636-sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies
Status: COMPLETED
Conditions: Leukemia|Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Chronic Myeloid Leukemia|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndrome|Paroxysmal Nocturnal Hemoglobinuria|Hodgkin's Lymphoma|Non-Hodgkin Lymphoma
Interventions: DRUG: Systematic chemotherapy and antibodies|PROCEDURE: Allogeneic stem cell transplantation|DEVICE: Miltenyi CliniMACS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Adolescent Vaccine Reminder Notices Sent Via Preferred Method of Communication on HPV Vaccination
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Vaccines
Interventions: BEHAVIORAL: Reminder Sent Via Preferred Method of Communication|BEHAVIORAL: Reminder Sent Via Mailed Letter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TQ05105 Tablet for Myelofibrosis Treatment in Ruxolitinib-Resistant or Intolerant Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelofibrosis
Interventions: DRUG: TQ05105 Tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine Challenge Study With JNJ-40411813
Status: COMPLETED
Conditions: Perceptual Disorders|Confusion|Schizophrenia
Interventions: DRUG: JNJ-40411813|DRUG: normal saline|DRUG: ketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Vinh Wellness Collagen on Skin Health
Status: COMPLETED
Conditions: Skin Manifestations|Skin Abnormalities
Interventions: DIETARY_SUPPLEMENT: Vinh Wellness Collagen|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients.
Status: RECRUITING
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: DRUG: Cisplatin|DRUG: 5-FU|RADIATION: Radiation therapy|DRUG: Cetuximab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of an Aerobic Exercise Programme in Stroke Patients
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: Aerobic exercise group|BEHAVIORAL: Control group|BEHAVIORAL: Follow-up first aerobic exercise group|BEHAVIORAL: Follow-up control group|BEHAVIORAL: Follow-up second aerobic exercise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Visual Function and Optics in Intraocular Lenses
Status: ENROLLING_BY_INVITATION
Conditions: Cataract
Interventions: PROCEDURE: Monofocal IOL|PROCEDURE: Multifocal IOL|PROCEDURE: Toric IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Femoral Nerve Blocks: Relative Effects of Basal Infusion and Bolus Doses on Sensory and Motor Function
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: Continuous Infusion|PROCEDURE: Bolus Administered
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolomic Profile and Proteasic Activity as Biomarkers for Early Detection of Arterial Vasospas in Arterial Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Status: UNKNOWN
Conditions: Subarachnoid Hemorrhage (SAH) From Ruptured Aneurysm
Interventions: OTHER: Blood draw and cerebrospinal fluid draw
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer|Colorectal Adenocarcinoma|Pancreatic Adenocarcinoma|Metastatic Pancreatic Cancer
Interventions: DRUG: Durvalumab|BIOLOGICAL: CV301|DRUG: Capecitabine|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Zylet vs Lotemax, Tobramycin and Vehicle in Pediatric Blepharoconjunctivitis
Status: COMPLETED
Conditions: Conjunctivitis
Interventions: DRUG: loteprednol etabonate and tobramycin|DRUG: loteprednol etabonate|DRUG: Tobramycin|DRUG: Vehicle of Zylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Idiopathic Membranous Nephropathy With Tripterygium Wilfordii Plus Steroid vs Tacrolimus Plus Steroid
Status: COMPLETED
Conditions: Idiopathic Membranous Nephropathy
Interventions: DRUG: Tripterygium wilfordii|DRUG: FK506
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimising Pacemaker Therapy Using Multi-point Pacing (the OPT-MPP Study)
Status: COMPLETED
Conditions: Heart Failure, Systolic
Interventions: DEVICE: Multi-point pacing|DEVICE: Standard settings
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Heart Rate Variability (HRV) Biofeedback to Treat Ulcerative Colitis
Status: NOT_YET_RECRUITING
Conditions: Ulcerative Colitis
Interventions: BEHAVIORAL: HRV biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of AHEs on DrA in Postpartum Women
Status: COMPLETED
Conditions: Diastasis Recti
Interventions: OTHER: Abdominal Hypopressive Training|OTHER: Conventional Physical therapy for DrA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Novel Drug Dimebon in Patients With Huntington's Disease
Status: COMPLETED
Conditions: Huntington's Disease
Interventions: OTHER: Placebo|DRUG: Dimebon
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Cumulative Dose Study to Evaluate the Safety and Efficacy of Albuterol in a Dry Powder Inhaler and an HFA MDI (Hydrofluoroalkane Metered Dose Inhaler)
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Albuterol dry powder inhaler|DRUG: Albuterol HFA MDI (hydrofluoroalkane metered dose inhaler)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Management in Response to Exparel vs. Standard Bupivicaine
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Liposomal Bupivicaine|DRUG: 0.25% standard bupivicaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis
Status: COMPLETED
Conditions: Seasonal Allergic Rhinitis
Interventions: DRUG: levocetirizine dihydrochloride|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomaterial Clinical Performance in a Socket Preservation Model
Status: UNKNOWN
Conditions: Bone Loss|Alveolar Bone Resorption
Interventions: DEVICE: Socket Preservation - Bond Apatite synthetic bone substitute|PROCEDURE: Socket healing - No Filler
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alpha-synuclein in Cerebrospinal Fluid to Differentiate Alzheimer's Disease From Lewy Body Disease.
Status: UNKNOWN
Conditions: "Alzheimer's Disease" and "Lewy Body Disease"
Interventions: OTHER: MRI|PROCEDURE: lumbar puncture|BEHAVIORAL: neuropsychological tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pragmatic, Randomized Evaluation of Statin Active Choice to Reach Improved Outcomes Based on Evidence
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: BEHAVIORAL: Active choice|BEHAVIORAL: Social comparison feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH