pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures
Status: RECRUITING
Conditions: Electroencephalographic Neonatal Seizures|Epilepsy
Interventions: DRUG: Lacosamide intravenous|DRUG: Lacosamide oral|OTHER: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tirelizumab in Combination With Carboplatin and Polymeric Micellar Paclitaxel for Neoadjuvant Therapy in cN+ HNSCC
Status: NOT_YET_RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma|Head and Neck Cancer|HNSCC|Head Cancer Neck
Interventions: DRUG: Carboplatin|DRUG: Tislelizumab|DRUG: Polymeric Micellar Paclitaxel|PROCEDURE: Surgical Resection of Primary +/- Neck Dissection|RADIATION: Post-operative radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POCUS Assessment of Bladder Fullness for Girls Awaiting Radiology-Performed Transabdominal Pelvic Ultrasound
Status: COMPLETED
Conditions: Abdominal Pain|Pelvic Pain
Interventions: OTHER: point-of-care ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Effect of Docosa-Hexanoic Acid (DHA) Supplements During Pregnancy on Newborn Outcomes in India.
Status: COMPLETED
Conditions: Pregnancy
Interventions: DIETARY_SUPPLEMENT: Docosa-hexaenoic acid (DHA)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Drug-drug Interaction Study of Midazolam and AT-527 (R07496998)
Status: COMPLETED
Conditions: Healthy Volunteer Study
Interventions: DRUG: AT-527 550 mg + midazolam|DRUG: AT-527 550 mg + midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remote Ischemic Conditioning for Avoiding Recurrence of Symptomatic Intracranial Atherosclerotic Stenosis (sICAS)
Status: UNKNOWN
Conditions: Intracranial Atherosclerosis
Interventions: DEVICE: Doctormate® (200mmHg)|DEVICE: Doctormate® (60mmHg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Protection of ACD III on Erythrocytes in Intraoperative Blood Salvage During Cardiopulmonary Bypass
Status: UNKNOWN
Conditions: Red Blood Cell Disorder
Interventions: COMBINATION_PRODUCT: blood preservation solution III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Omalizumab to Mepolizumab Switch Study in Severe Eosinophilic Asthma Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Mepolizumab 100mg SC|DRUG: Albuterol/salbutamol MDIs|DRUG: Omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Diabetic Neuropathy With Liraglutide
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1|Type 1 Diabetes Mellitus
Interventions: DRUG: Placebo treatment|DRUG: Liraglutide treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Cetrelimab in Participants With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: Cetrelimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Multiple Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of ACHN-975 in Healthy Volunteers
Status: TERMINATED
Conditions: Healthy Volunteer
Interventions: DRUG: ACHN-975|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Second Course of Therapy for Resistant Patent Ductus Arteriosus (PDA)
Status: WITHDRAWN
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Indomethacin|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy (SBRT) for Localized Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: SBRT|DRUG: Androgen deprivation therapy (ADT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Study of Dachengqi Decoction Combined With Probiotic L92 to Improve the Prognosis of Patients With Severe Abdominal Hypertension
Status: UNKNOWN
Conditions: Dachengqi Decoction|Probiotic L92
Interventions: DRUG: Dachengqi decoction|DRUG: probiotic L9|OTHER: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Bevacizumab With HSRT vs BVZ Alone for GBM at First Recurrence
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioma|Recurrent Glioma
Interventions: RADIATION: Hypofractionated Stereotactic Radiotherapy|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Experimental and Clinical Studies of Retinal Stimulation
Status: RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: DEVICE: New visual processing unit (VPU) with asymmetric waveforms|DEVICE: New VPU with bipolar stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial of the ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Recurrent Brain Tumors
Status: RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: WSD0628
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety and Efficacy of Nemolizumab in Participants With Moderate-to-Severe Atopic Dermatitis
Status: RECRUITING
Conditions: Moderate-to-Severe Atopic Dermatitis
Interventions: DRUG: Nemolizumab|DRUG: Nemolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: "Comparison of Intra-articular of 2% Ropivacaine vs. 7.5% Ropivacaine in Postoperative of Knee Arthroscopy"
Status: COMPLETED
Conditions: Knee Arthroscopy|Acute Pain
Interventions: DRUG: Ropivacaine 7.5% Injectable Solution|DRUG: Ropivacaine 2% Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease
Status: TERMINATED
Conditions: Mitochondrial Diseases
Interventions: DRUG: Cysteamine Bitartrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intravenous Amantadine on Gait Freezing in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: amantadine sulfate|DRUG: 0.9% sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Status: COMPLETED
Conditions: Transcranial Direct Current Stimulation|Working Memory|Pain
Interventions: DEVICE: Anodal tDCS on DLPFC|DEVICE: Anodal tDCS on M1|DEVICE: Sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN
Status: RECRUITING
Conditions: C3 Glomerulopathy|Idiopathic Immune-complex-membranoproliferative Glomerulonephritis
Interventions: DRUG: LNP023
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BCG-induced Epigenetic Modifications in the NEXT Generation
Status: ACTIVE_NOT_RECRUITING
Conditions: Trained Immunity|BCG Vaccine|Epigenetics
Interventions: BIOLOGICAL: BCG-Vaccine SSI [Statens Serum Institut]) Danish strain 1331|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Stepping Up for Safety: Improving Teamwork at the Planned Parenthood Affiliates Through the TeamSTEPPS Model
Status: COMPLETED
Conditions: Improving Team Work at the Planned Parenthood Affiliates
Interventions: BEHAVIORAL: Team training using the TeamSTEPPS model
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Assessment of Sodium Sulfide in Subjects With Impaired Renal Function
Status: TERMINATED
Conditions: Renal Impairment
Interventions: DRUG: Sodium Sulfide|DRUG: Sodium Sulfide|DRUG: Sodium Sulfide|DRUG: Sodium Sulfide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: DRUG: ONO-4641|DRUG: ONO-4641|DRUG: ONO-4641|DRUG: ONO-4641|DRUG: ONO-4641|DRUG: ONO-4641
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of ADW S-100 Ionized Water Nasal Spray in Decreasing Symptoms of Allergic Rhinitis
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DEVICE: Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Granix to Disrupt the Bone Marrow Microenvironment in Patients With Multiple Myeloma Undergoing Autologous Transplantation
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Granix|DRUG: High dose melphalan (HDR)|PROCEDURE: Autologous Stem Cell Transplant (ASCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dextenza in the Post-op Management of Vitreoretinal Surgeries
Status: RECRUITING
Conditions: Vitreoretinal Surgery|Ocular Inflammation|Post-operative Pain|Post-Operative Inflammation
Interventions: DRUG: Dexamethasone Ophthalmic Insert|DRUG: Prednisolone Acetate 1% Oph Susp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee
Status: TERMINATED
Conditions: Severe Osteoarthritis of the Knee
Interventions: BIOLOGICAL: 4 mL injection of AMPION™
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma
Status: NOT_YET_RECRUITING
Conditions: Cholangiocarcinoma|Klatskin Tumor|Bile Duct Cancer|Liver Cancer
Interventions: PROCEDURE: Intraductal biliary radiofrequency ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness and Cost-effectiveness of Medical Advice Given by Telephone for Patients Calling for Primary Care
Status: COMPLETED
Conditions: Isolated Fever|Gastroenteritis Symptoms
Interventions: OTHER: focused Telephonic Medical Advice|OTHER: Usual practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Expanded Access Program of Pegfilgrastim (Neulastim) in Participants With Non-Hodgkin's Lymphoma (NHL)
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: Chemotherapy|DRUG: Immunochemotherapy|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Virtual Training to In-Person Training of Helping Babies Breathe in Ethiopia
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Death|Birth Asphyxia
Interventions: BEHAVIORAL: HBB Virtual Training|BEHAVIORAL: HBB In-person Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) for Recurrent, Metastatic, or Unresectable HER2-Positive Salivary Gland Cancer
Status: RECRUITING
Conditions: Metastatic Salivary Gland Carcinoma|Recurrent Salivary Gland Carcinoma|Stage III Major Salivary Gland Cancer AJCC v8|Stage IV Major Salivary Gland Cancer AJCC v8|Unresectable Salivary Gland Carcinoma
Interventions: DRUG: Docetaxel|OTHER: Questionnaire Administration|BIOLOGICAL: Trastuzumab|BIOLOGICAL: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Probiotics on the Health of Normal Young Males
Status: COMPLETED
Conditions: Inflammation|Dyslipidemia
Interventions: DIETARY_SUPPLEMENT: Probiotic yogurt|DIETARY_SUPPLEMENT: Acidified milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Chronic Orofacial Pain
Status: TERMINATED
Conditions: Orofacial Pain
Interventions: DEVICE: real tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of 15-Valent Pneumococcal Conjugate Vaccine in Healthy Volunteers Aged Above 2 Months
Status: UNKNOWN
Conditions: Pneumonia, Pneumococcal
Interventions: BIOLOGICAL: 15-Valent Pneumococcal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Fluoxetine Versus Citalopram Therapy to Control Postmenopausal Vasomotor Syndrome
Status: COMPLETED
Conditions: Postmenopause|Hot Flashes
Interventions: DRUG: Fluoxetine 20 MG|DRUG: Citalopram 20mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Radiotherapy Alone Versus CCRT With Temozolomide in Grade III Gliomas Without 1p/19q Codeletion
Status: UNKNOWN
Conditions: Anaplastic Glioma of Brain|Loss of Chromosomes 1p/19q
Interventions: DRUG: Temozolomide (Temodal)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Physical Therapy in Patients With Sepsis
Status: TERMINATED
Conditions: SEPTIC SHOCK|SEPSIS SYNDROME|Multiple Organ Dysfunction Syndrome
Interventions: OTHER: Early and Active Physical Therapy|OTHER: Passive Range of Motion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chemotherapy Induction and Chemoradiotherapy in Patients With Esophageal Carcinoma
Status: TERMINATED
Conditions: Esophageal Cancer
Interventions: DRUG: 5-FU|DRUG: Cisplatin|DRUG: Taxotere|BIOLOGICAL: Cetuximab|RADIATION: Radiation during chemoradio-immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women's Health Initiative Strong and Healthy Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Stroke|Cardiovascular Mortality|Hip Fractures|Falls|Mortality|Venous Thromboembolic Event|Peripheral Artery Disease|Physical Function|Coronary Revascularization|Mobility and Independence|Clinical (Non-hip) Fractures|Sleep|Depressive Symptoms
Interventions: BEHAVIORAL: Physical Activity
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Video-based Cardiac Rehabilitation Education in Patients With CIEDs- a Randomized Controlled Trial
Status: COMPLETED
Conditions: Patients With Cardiac Implantable Electronic Devices
Interventions: OTHER: education video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: GnRH Agonist Versus hCG Trigger in Ovulation Induction With Intrauterine Insemination.
Status: COMPLETED
Conditions: Ovulation Induction
Interventions: DRUG: GnRHa (Fertipeptil 0.1mg)|DRUG: hCG (Pregnyl 5000IU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia Induction Schemes of Electroconvulsive Convulsions in Patients With Depression Based on EEG Monitoring
Status: RECRUITING
Conditions: Depression|Electroconvulsive Therapy|Electroencephalography
Interventions: OTHER: Index of consciousness+Anesthetic（propofol）+Muscle relaxant（Succinylcholine）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating Bazedoxifene Dose-Response in Japanese Patients With Postmenopausal Osteoporosis.
Status: COMPLETED
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Bazedoxifene|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose:
Clinical trial: The Significance of Glucose Intolerance in the Pathogenesis of Idiopathic Axonal Polyneuropathy
Status: TERMINATED
Conditions: Idiopathic Axonal Polyneuropathy|Abnormal OGTT
Interventions: PROCEDURE: Optical coherence tomography,Fluorescein angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Psychological Symptom Change in Veterans After Six Sessions of EFT (Emotional Freedom Techniques)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: BEHAVIORAL: EFT (Emotional Freedom Techniques)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: XEBRA Study: An Observational Study of Xeloda (Capecitabine) in Combination With Docetaxel in First Line in Participants With HER2-Negative Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: capecitabine|DRUG: docetaxel
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Routine Airway Management
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: orotracheal intubation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias.
Status: ACTIVE_NOT_RECRUITING
Conditions: Ventricular Tachycardia
Interventions: DRUG: Dantrolene/Ryanodex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hydrocolloid Tape and Facial Massage in Premature Infants During Noninvasive Mechanical Ventilation
Status: RECRUITING
Conditions: Nasal Injury
Interventions: OTHER: Hydrocolloid barrier group|OTHER: Facial Massage group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Everolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: DRUG: everolimus|GENETIC: DNA analysis|GENETIC: protein analysis|GENETIC: western blotting|OTHER: flow cytometry|OTHER: laboratory biomarker analysis|PROCEDURE: biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours)
Status: TERMINATED
Conditions: Neoplasms
Interventions: DRUG: BI 905677
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeat Doses of BAY 1817080 in Healthy Males & Proof of Concept in Chronic Cough Patients
Status: COMPLETED
Conditions: Cough
Interventions: DRUG: BAY1817080|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients
Status: COMPLETED
Conditions: Neurotoxicity|Pain|Peripheral Neuropathy|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ketamine/amitriptyline NP-H cream|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Leveraging an Existing Large-scale Safe Water Program to Deliver Nutrition Messages at a Low Marginal Cost
Status: COMPLETED
Conditions: Child Malnutrition
Interventions: BEHAVIORAL: Provision of information on safe water|BEHAVIORAL: Provision of information on safe water and child nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Feasibility Study of Multimodal Exercise/Nutrition/Anti-inflammatory Treatment for Cachexia - the Pre-MENAC Study
Status: COMPLETED
Conditions: Cancer|Cachexia
Interventions: OTHER: Multimodal intervention|OTHER: Standard care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation Patient Satisfaction After Passive Bladder Catheter Removal Compared to Active Removal
Status: RECRUITING
Conditions: Urologic Diseases
Interventions: PROCEDURE: Passive indwelling urinary catheter removal|PROCEDURE: Active indwelling catheter removal by a nurse
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Aaerosol Combined With Intravenous Antibiotics for the Treatment of Multidrug Resistant GNB Pneumonia
Status: UNKNOWN
Conditions: Ventilator Associated Pneumonia|Multi-antibiotic Resistance
Interventions: DRUG: aerosol antibiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bioequivalence Study of 8 mg Perindopril Tert-butylamine / 2.5 mg Indapamide Tablets Versus 10 mg Perindopril Arginine / 2.5 mg Indapamide Film-coated Tablets in Healthy Volunteers
Status: COMPLETED
Conditions: Bioequivalence|Healthy Subjects
Interventions: DRUG: PERINDOPRES® DUO 8 mg perindopril tert-butylamine / 2.5 mg indapamide tablets|DRUG: Noliterax® 10 mg/2.5 mg 10 mg perindopril arginine / 2.5 mg indapamide film-coated tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: adalimumab|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Back on My Feet: Emotional Recovery From Fall Injury
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Subsyndromal Posttraumatic Stress Disorder|Fear of Falling
Interventions: BEHAVIORAL: Exposure-based Cognitive Behavioral Therapy|BEHAVIORAL: Relaxation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Preliminary Efficacy of IVMED-80 Eye Drops in Keratoconus Patients
Status: COMPLETED
Conditions: Keratoconus|Corneal Ectasia
Interventions: DRUG: IVMED-80|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective Evaluation of ProChondrix CR for Repair of Articular Cartilage Defects on Femoral Condyle and Patella
Status: ACTIVE_NOT_RECRUITING
Conditions: Cartilage Injury|Cartilage Damage
Interventions: PROCEDURE: Cryopreserved Osteochondral Allograft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bougie Assisted Endotracheal Intubation in Air-Q Intubating Laryngeal Mask And Fastrach Intubating Laryngeal Mask
Status: COMPLETED
Conditions: Intubation;Difficult|Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Interventions: DEVICE: Endotracheal tube introducers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Gemcitabine/Cisplatin Versus S-1/Cisplatin in Advanced Biliary Cancer
Status: TERMINATED
Conditions: Metastatic Biliary Tract Cancer|Locally Advanced Biliary Tract Cancer
Interventions: DRUG: Gemcitabine, Cisplatin|DRUG: S-1, Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-articular Injection in Arthroscopic Management of Temporomandibular Diseases
Status: UNKNOWN
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Temporomandibular joint arthroscopy plus intra-articular injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Corticosteroids+5-aminosalicylic Acids Compared to Corticosteroids Alone (for Ulcerative Colitis).
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: 5-ASA|DRUG: Corticosteroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Vaccine Component P3C541b in HIV-1 Seronegative Human Subjects
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: P3C541b Lipopeptide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Randomized Study of Stereotactic Body Radiotherapy vs. Conventional Radiation for Spine Metastasis
Status: TERMINATED
Conditions: Primary Tumor|Metastatic Cancer
Interventions: RADIATION: Radiosurgery/SBRT|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy and Safety of the Combination of SCTA01 & SCTA01C in Outpatients With COVID-19
Status: WITHDRAWN
Conditions: COVID-19
Interventions: DRUG: SCTA01 and SCTA01C|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of DE-120 Injectable Solution for Age-related Macular Degeneration
Status: COMPLETED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: DE-120|DRUG: Aflibercept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting High Risk Populations With Enhanced Reactive Case Detection in Southern Lao Peoples Democratic Republic
Status: UNKNOWN
Conditions: Plasmodium Falciparum Malaria|Plasmodium Vivax Malaria
Interventions: OTHER: Household Reactive Case Detection|OTHER: RACD of cases' co-workers/co-travelers|OTHER: Case Management and Follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Vitamin D Level and Risk of Infections in Cirrhotic Patients
Status: UNKNOWN
Conditions: Vitamin D Deficiency|Infection|Liver Cirrhosis
Interventions: DIAGNOSTIC_TEST: 3- Serum 25-Hydroxy Vitamin D level will be measured by Competitive ELISA technique
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base
Status: RECRUITING
Conditions: Chordoma|Chondrosarcoma
Interventions: RADIATION: 5-fraction hipofractionated protontheray
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rucaparib and Irinotecan in Cancers With Mutations in DNA Repair
Status: COMPLETED
Conditions: Solid Tumor, Unspecified, Adult
Interventions: DRUG: Rucaparib|DRUG: Irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Screw and Suture Button Technique Results in Ankle Syndesmosis Injuries
Status: COMPLETED
Conditions: Ankle Injuries|Syndesmotic Injuries|Tibiofibular; Dislocation Distal
Interventions: DEVICE: Screw fixation|DEVICE: Suture button
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Barley and Rice Mixture Effects on Blood Glucose
Status: COMPLETED
Conditions: Blood Glucose|Dietary Fiber|Hunger
Interventions: OTHER: 100% steel cut barley|OTHER: 100% barley flakes|OTHER: 50/50 rice-barley mix|OTHER: 80/20 rice-barley mix|OTHER: 100% rice|OTHER: white bread
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT Assessment
Status: NOT_YET_RECRUITING
Conditions: Classical Hodgkin Lymphoma|Child|Adolescent|Young Adult|Metabolic Response|Survival|Treatment|Brentuximab Vedotin|PET Scan
Interventions: DRUG: Brentuximab Vedotin for Injection|RADIATION: response-adapted radiation|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Prednisone|DRUG: Cyclophosphamide|DRUG: Dacarbazine|DRUG: Tislelizumab Injection|DRUG: Bedamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin in Patients With Chronic Hepatitis C - An Observational Study in Germany (LIFE-C)
Status: COMPLETED
Conditions: Chronic Hepatitis C
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diagnostic Accuracy of Teledermatology in Patch Test Interpretation
Status: ACTIVE_NOT_RECRUITING
Conditions: Teledermatology
Interventions: DIAGNOSTIC_TEST: In-clinic interpretation|DIAGNOSTIC_TEST: Photo interpretation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pilot Study of Home Blood Pressure Control Program (eBP Control)
Status: COMPLETED
Conditions: Hypertension|Cardiovascular Disease
Interventions: BEHAVIORAL: HBPM+website+patient navigator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose-Escalation Study of SPYK04 in Patients With Locally Advanced or Metastatic Solid Tumors (With Expansion).
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced or Metastatic Solid Tumors
Interventions: DRUG: SPYK04
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Recovery After Adductor Canal Block Analgesia in Unilateral Prosthetic Knee Surgery
Status: RECRUITING
Conditions: Unilateral Primary Osteoarthritis of Knee
Interventions: PROCEDURE: Unilateral prosthetic knee surgery|PROCEDURE: Analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Automated Retinal Image Analysis System (EyeQuant) for Computation of Vascular Biomarkers
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Alzheimer Disease|Vascular Dementia
Interventions: DIAGNOSTIC_TEST: Retinal fundus photography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Clinical Study to Assess the Safety and Clinical Performance of a New Dressing (PICO7Y) in Breast Surgery Patients
Status: COMPLETED
Conditions: Oncoplastic Breast Surgery|Bilateral Surgery
Interventions: DEVICE: PICO7Y
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Teach Back to Improve Postpartum Maternal-infant Health Among Women With Limited Maternal Health Literacy
Status: COMPLETED
Conditions: Pregnant Women
Interventions: BEHAVIORAL: Teach-back method
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TECR & ECM Placement for Esophageal High Grade Dysplasia
Status: TERMINATED
Conditions: Barrett Esophagus|Esophagus|High Grade Dysplasia
Interventions: DEVICE: Subjects undergoing TECR with ECM placement (ACell MatriStem, Boston Scientific WallFlex))
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Usage Of Artificial Intelligence-Integrated Usg In Application of Pectoral Block In Mastectomies
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: PROCEDURE: Performed PECS II block with AI integrated USG|PROCEDURE: Performed PECS II block with conventional USG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CHABLIS-SC1: A Study of the Efficacy and Safety of Subcutaneous Blisibimod in Subjects With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: blisibimod|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Fecal Microbiota Transplantation in Ankylosing Spondylitis (AS) Patients.
Status: UNKNOWN
Conditions: Ankylosing Spondylitis
Interventions: OTHER: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Clinical Accuracy of Gallium-68 PSMA PET/CT Imaging in Patients With Biochemical Recurrence of Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms|Prostatic Neoplasms, Castration-Resistant
Interventions: DRUG: Ga-68 PSMA-HBED-CC PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ERK 1/2 Signaling in Ibrutinib Resistant B-cell Malignancies
Status: WITHDRAWN
Conditions: Chronic Lymphocytic Leukemia|Waldenstrom Macroglobulinemia|Mantle Cell Lymphoma|Marginal Zone Lymphoma
Interventions: DRUG: Ibrutinib|DRUG: LY3214996
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of an Investigational Influenza Vaccine (Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection (CCII)
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated seasonal influenza vaccine (split virus, Vero cell-derived)|OTHER: Phosphate buffered saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Letrozole in Tubal Ectopic Pregnancy
Status: RECRUITING
Conditions: Tubal Pregnancy
Interventions: OTHER: Placebos|DRUG: Letrozole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AGSPT201 Tab contains S-pantoprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection in Liver Transplant Candidates (EZE-2)
Status: UNKNOWN
Conditions: Hepatitis C
Interventions: DRUG: Ezetimibe
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Intensity Laser Therapy (HILT) on Myofascial Trigger Points.
Status: NOT_YET_RECRUITING
Conditions: Myofascial Trigger Point Pain (MTrP)
Interventions: DEVICE: High intensity laser therapy (HILT)|DEVICE: Therapeutic Ultrasound (US)|PROCEDURE: Stretching exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
Status: COMPLETED
Conditions: Old Age; Cachexia|Dietary Habits|Sarcopenia|Protein Malnutrition|Patient Participation
Interventions: OTHER: educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Feasibility Pilot of Bright Light in the Intensive Care Unit
Status: COMPLETED
Conditions: Circadian Rhythm Sleep Disorder, Unspecified
Interventions: DEVICE: standard light|DEVICE: 10,000 lux bright light, 4 hours|DEVICE: 10,000 lux bright light, 8 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
Status: COMPLETED
Conditions: Stroke|Cerebrovascular Accident (CVA)|Hemiparesis
Interventions: DEVICE: Transcutaneous Vagus Nerve Stimulation (tVNS)|DEVICE: Sham Transcutaneous Vagus Nerve Stimulation (tVNS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Obstructive Sleep Apnea Treatment to Improve Cardiac Rehabilitation
Status: TERMINATED
Conditions: Obstructive Sleep Apnea|Coronary Heart Disease
Interventions: DEVICE: CPAP|BEHAVIORAL: HLSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect Comparison of Electro-acupuncture and Prucalopride for Severe Chronic Constipation: a Randomized Controlled Trial
Status: COMPLETED
Conditions: Constipation
Interventions: PROCEDURE: acupuncture|DRUG: Prucalopride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Immunogenicity of HIV-1 Recombinant Envelope Glycoprotein gp160
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: Hepatitis B Vaccine (Recombinant)|BIOLOGICAL: gp160 Vaccine (MicroGeneSys)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs
Status: RECRUITING
Conditions: Advanced Cancer|Solid Tumor|Haematological Malignancy
Interventions: DRUG: Alectinib|DRUG: Cobimetinib|DRUG: Vismodegib|DRUG: Trastuzumab+Pertuzumab|DRUG: Entrectinib|DRUG: Atezolizumab|DRUG: Vemurafenib|DRUG: Regorafenib|DRUG: Apalutamide|DRUG: Abemaciclib|DRUG: Tepotinib|DRUG: Dabrafenib|DRUG: Trametinib|DRUG: Dabrafenib+Trametinib|DRUG: Pemigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remimazolam Tosilate Sedation and Midazolam Sedation in Dental Patients
Status: COMPLETED
Conditions: Sedation Complication|Midazolam|Remimazolam
Interventions: DRUG: Fentanyl|DRUG: Flurbiprofen|DRUG: Midazolam|DRUG: Remimazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions
Status: TERMINATED
Conditions: Central Retinal Vein Occlusion|Branch Retinal Vein Occlusion
Interventions: DRUG: nicotinic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib in Treating Anemic MPN Patients
Status: RECRUITING
Conditions: Myeloproliferative Neoplasm
Interventions: DRUG: Vactosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Replacement in Insulin Resistant South Asians
Status: TERMINATED
Conditions: Vitamin D Deficiency|Insulin Resistance
Interventions: DRUG: Vitamin D3 cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Rapamycin on Tolerance-related Biomarkers on Stable Liver Transplant Recipients
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: DRUG: Sirolimus|DRUG: Calcineurin inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Psychosocial Transitional Group to Improve Adaptation, Coping and Mental Health Outcomes Following Trauma
Status: ACTIVE_NOT_RECRUITING
Conditions: Musculoskeletal Injury|Traumatic Injury
Interventions: BEHAVIORAL: Supportive Expressive Group Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Age-Related Eye Disease Study (AREDS)
Status: COMPLETED
Conditions: Macular Degeneration|Cataract|Lens Opacities
Interventions: DIETARY_SUPPLEMENT: Antioxidants|DIETARY_SUPPLEMENT: Zinc|DIETARY_SUPPLEMENT: Antioxidants and zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Study of Prexasertib and Olaparib in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumor
Interventions: DRUG: Prexasertib|DRUG: Olaparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Clinical Effectiveness of Oral Probiotic MIYA-BM to Prevent Recurrent Clostridium Difficile Infections
Status: WITHDRAWN
Conditions: Clostridium Difficile Infection
Interventions: DRUG: MIYA-BM Fine Granules (CBM588)|DRUG: Placebo Fine Granules (without CBM588)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iliopsoas Plane Block vs PENG Block for Hip Arthroplasty
Status: RECRUITING
Conditions: Hip Fractures|Hip Injuries|Hip Arthropathy
Interventions: OTHER: Postoperative analgesia management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preoperative Abdominal Enhanced CT, 18F-FDG PET/CT and 68Ga-FAPI PET/CT in Peritoneal Carcinomatosis of Gastric Cancer
Status: UNKNOWN
Conditions: Enhanced CT|18F-FDG PET/CT|68Ga-FAPI PET/CT|Gastric Cancer|Peritoneal Carcinomatosis
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI PET/CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC