pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Sarcoma,Soft Tissue|Brachytherapy|Poly(ADP-ribose) Polymerase Inhibitors
Interventions: DRUG: Fluzoparib|PROCEDURE: Radioactive particle implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Light Delivery Methods for Lung Cancer Photodynamic Therapy - A Pilot Study
Status: UNKNOWN
Conditions: Non-small Cell Lung Cancer (NSCLC)|Lung Metastasis
Interventions: DRUG: Porfimer sodium|DRUG: Ethiodized oil|PROCEDURE: Novel light delivery methods of photodynamic therapy|DEVICE: Fiber optic
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed/Refractory Multiple Myeloma
Interventions: BIOLOGICAL: CB-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RC48 Combined With Tislelizumab for Second-line Treatment of HER2 Expression in Recurrent Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer Recurrent
Interventions: DRUG: RC48 + Tislelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hemodilution Versus Ranibizumab in Early-onset Central Retinal Vein Occlusion
Status: COMPLETED
Conditions: Central Retinal Vein Occlusion
Interventions: DRUG: ranibizumab|PROCEDURE: hemodilution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injection
Status: COMPLETED
Conditions: Macular Degeneration|Wet Macular Degeneration
Interventions: DRUG: Intravitreal aflibercept injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation Study of the PostOperative Nausea and Vomiting Prediction Rule
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DEVICE: Automatic Risk Presentation in the operating room|OTHER: Education|OTHER: Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Nerve Blockade Performed Prior to Surgical Intervention Versus Following Surgical Intervention
Status: ACTIVE_NOT_RECRUITING
Conditions: Pain|Shoulder Injury
Interventions: PROCEDURE: Preemptive Interscalene Block - Single Shot|PROCEDURE: Postoperative Interscalene Block- Single Shot|PROCEDURE: Preemptive Interscalene Block - Catheter|PROCEDURE: Postoperative Interscalene Block - Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Designed to Test the Effectiveness and Safety of Treating Patients With Lacosamide for Migraine Prophylaxis
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Lacosamide|OTHER: Placebo|DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Medicoeconomic Evaluation of Two Surgical Techniques for Lobectomy in the Lung Cancer
Status: TERMINATED
Conditions: Lung Cancer|Lobectomy
Interventions: PROCEDURE: Video-thoracoscopy|PROCEDURE: thoracotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Evaluating the Safety and Efficacy of Venetoclax in Combination With Trastuzumab Emtansine in Patients With Previously Treated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Venetoclax|DRUG: Trastuzumab emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Loop Drainage Versus Incision and Drainage for Abscesses
Status: WITHDRAWN
Conditions: Abscess of Skin and/or Subcutaneous Tissue
Interventions: PROCEDURE: Loop drainage|PROCEDURE: Incision and drainage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Labetuzumab Govitecan in Participants With Metastatic Colorectal Cancer
Status: TERMINATED
Conditions: Metastatic Colorectal Cancer|Colon Cancer|Rectal Cancer
Interventions: DRUG: Labetuzumab Govitecan (LG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Motivational Interview Intervention for Caregivers of Individuals With Severe Mental Disorders
Status: NOT_YET_RECRUITING
Conditions: Caregiver|Motivational Interview|Mental Disorder
Interventions: BEHAVIORAL: Motivational İnterview|OTHER: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III Obesity
Status: UNKNOWN
Conditions: Obesity Complicating Childbirth|Obesity|Labor Onset and Length Abnormalities|Pregnancy, High Risk|Cesarean Section Complications
Interventions: PROCEDURE: Caesarean section|PROCEDURE: Induction of Labour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Use of (Oral) Ketotifen for the Treatment of Fibromyalgia: A Pilot Study
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Ketotifen|DRUG: Placebo (Sugar Pill)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Multicenter Study of Long-Term Clinical Outcomes of Subcutaneous Immune Globulin IgPro20 in Subjects With Primary Immunodeficiency (Japan Study)
Status: COMPLETED
Conditions: Primary Immune Deficiency
Interventions: BIOLOGICAL: Immune globulin subcutaneous (Human)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goserelin 10.8mg Injection in Treatment of Advanced Prostate Cancer
Status: RECRUITING
Conditions: Advanced Prostate Cancer
Interventions: DRUG: Inj. Goserelin (Test) Subcutaneously|DRUG: Inj. Zoladex (Reference) Subcutaneously
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ORM-12741 in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: ORM-12741|DRUG: ORM-12741|DRUG: Placebo for ORM-12741
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telephone Support for Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Education/Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE
Status: NOT_YET_RECRUITING
Conditions: Pulmonary Embolism|Right Ventricular Dysfunction|Right Ventricular Failure
Interventions: DEVICE: Ultrasound-facilitated, catheter-directed lower-dose fibrinolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transcriptomes Breast, Ovarian and Leukocyte Hereditary Genes Predisposing to Breast and / or Ovarian Cancer
Status: COMPLETED
Conditions: Breast Cancer|Transcriptomes|Molecular Diagnostic|Ovarian Cancer
Interventions: OTHER: collection of a blood sample and breast and ovarian tissue|OTHER: use of a previous blood collection for patients
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study in Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA) Patients to Evaluate Work Productivity Before and After the Start of Adalimumab Therapy in Daily Practice in Belgium
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Psoriatic Arthritis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Depression in Adolescents. A Cerebral Structural, Diffusion, and Functional Magnetic Resonance Imaging Study
Status: UNKNOWN
Conditions: Adolescent Depression
Interventions: OTHER: -Diagnostic, clinical and psycho-behavioral assessments -Neuroimaging: T1-MRI, DTI-MRI, fMRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Pupillometry for cyp2d6 Phenotyping in Children Treated With Tramadol
Status: TERMINATED
Conditions: Drug Intolerance|Cytochrome P450 CYP2D6 Enzyme Deficiency|Drug Effect
Interventions: DEVICE: Pupillometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DEVICE: ACURATE neo2|PROCEDURE: minimalist approach|DEVICE: CoreValve Evolut Pro and Pro+|PROCEDURE: Standard of care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Sagittal Spinal Geometry in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: TheraTogs Orthotic Undergarment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: ifosfamide|DRUG: mercaptopurine|DRUG: methotrexate|DRUG: prednisone|DRUG: thioguanine|DRUG: vincristine sulfate|DRUG: vindesine|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Metastatic Leiomyosarcoma|Metastatic Liposarcoma|Unresectable Leiomyosarcoma|Unresectable Liposarcoma
Interventions: DRUG: Avelumab|DRUG: Trabectedin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of the Equimolar Mixture of Oxide Nitrous and Oxygen (EMONO) Associated With Audiovisuals in Children
Status: COMPLETED
Conditions: Pain, Acute|Child, Only|Nurse's Role|Nitrous Oxide
Interventions: OTHER: EMONO + audiovisuals tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Atorvastatin Versus Placebo to Reduce Cardiopulmonary Complications After Thoracic Surgery
Status: COMPLETED
Conditions: Thoracic Surgery
Interventions: DRUG: Atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lay User Evaluation of the Panbio™ HCV Self Test in an EU Population
Status: NOT_YET_RECRUITING
Conditions: Hepatitis C
Interventions: DIAGNOSTIC_TEST: Panbio™ HCV Self Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Paclitaxel-coated Luminor® Balloon Catheter Versus Uncoated Balloon Catheter in the Arteria Femoralis Superficialis
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Transluminal Angioplasty with Paclitaxel-coated Luminor® Balloon Catheter in the Superficial Femoral and Popliteal Arteries|DEVICE: Transluminal Angioplasty with and non-coated (CE-marked) plain old angioplasty balloon (POBA) catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pituitrin on the Patients With Pulmonary Hypertension Undergoing Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Cardiac Surgery|Hypertension, Pulmonary
Interventions: DRUG: Pituitrin|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Dental Implant Placement in the Sloped Alveolar Ridge
Status: UNKNOWN
Conditions: Atrophy of Edentulous Alveolar Ridge
Interventions: DEVICE: Sloped|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Psiguavin for Obesity Treatment (PSIGUAVIN)
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Overweight or Obesity
Interventions: DIETARY_SUPPLEMENT: Psiguavin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Conventional Physical Therapy in Patients With Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: DN and conventional PT|OTHER: Conventional PT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Plus Rituximab for Recurrent/Refractory CNS and Intraocular Lymphoma
Status: COMPLETED
Conditions: Recurrent/Refractory CNS|Intraocular Lymphoma
Interventions: DRUG: Lenalidomide|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of External Cold and Vibration (Buzzy Device) Versus the Conventional Technique on Pain Perception During Local Anesthesia Injection in Children.
Status: UNKNOWN
Conditions: Anesthesia|Anesthesia, Local|Vibration
Interventions: DEVICE: buzzy device|OTHER: Conventinal anasthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of JUVÉDERM VOLUMA® XC Injectable Gel for Correction of Temple Hollowing
Status: TERMINATED
Conditions: Temple Hollowing
Interventions: DEVICE: Juvéderm® VOLUMA XC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dabigatran Etexilate in Extended Venous Thromboembolism (VTE) Prevention After Hip Replacement Surgery
Status: COMPLETED
Conditions: Thromboembolism|Arthroplasty, Replacement, Hip
Interventions: DRUG: dabigatran etexilate|DRUG: dabigatran etexilate|DRUG: enoxaparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome
Status: COMPLETED
Conditions: Keratoconjunctivitis Sicca|Sjogren's Syndrome|Lupus Erythematosus, Systemic|Arthritis, Rheumatoid|Scleroderma, Systemic
Interventions: DRUG: Ophthalmic Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a Custom-made and Disposable Endoscope System for Biliary Tract
Status: COMPLETED
Conditions: Biliary Tract|Neoplasms|Stone - Biliary
Interventions: DEVICE: NCKU-scope-01 (a custom-made biliary endoscope system)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Vertical Ridge Augmentation With Autogenous Onlay Blocks Combined With Guided Bone Regeneration Versus Autogenous Bone Graft With Titanium Mesh in Posterior Mandible
Status: UNKNOWN
Conditions: Posterior Mandible With Deficient Ridge Height
Interventions: DEVICE: autogenous rings with GBR and autogenous graft with ti-mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: READI (Readiness Evaluation And Discharge Interventions) Study
Status: COMPLETED
Conditions: Discharge Transition of Patients Discharged to Home
Interventions: OTHER: RN-RHDS protocol|OTHER: RN-RHDS+PT-RHDS protocol|OTHER: RN-RHDS + PT-RHDS + NIAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: 11C-JNJ-63779586
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Intraarticular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Reconstruction
Interventions: DRUG: Tranexamic Acid Powder|PROCEDURE: Post-anterior cruciate ligament reconstruction (ACLR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigator-initiated Clinical Trial of MIKE-1
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Am80|DRUG: Gemcitabine|DRUG: nab-Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI Study
Status: RECRUITING
Conditions: Grade I Meningioma|Grade II Meningioma|Grade III Meningioma|Intracranial Neoplasm|Nerve Sheath Neoplasm|Pituitary Gland Adenoma|Schwannoma
Interventions: RADIATION: Hypofractionated Radiation Therapy|RADIATION: Photon Beam Radiation Therapy|RADIATION: Proton Beam Radiation Therapy|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral and Intravenous Iron in Patients Postoperative Cardiovascular Surgery Under Extracorporeal Circulation
Status: COMPLETED
Conditions: Anaemia
Interventions: DRUG: IV trivalent saccharose hydroxide ferrous|DRUG: Oral ferrous fumarate|DRUG: Oral and intravenous Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Status: RECRUITING
Conditions: Lactating Women on Select DOI|Breastfed Infants of Mothers on Select DOI
Interventions: DRUG: Tranexamic acid (TXA)|DRUG: labetalol|DRUG: metformin|DRUG: nifedipine|DRUG: clindamycin|DRUG: oxycodone|DRUG: azithromycin|DRUG: escitalopram|DRUG: sertraline|DRUG: ondansetron|DRUG: Ciprofloxacin|DRUG: Doxycycline|DRUG: Levofloxacin|DRUG: Methylphenidate|DRUG: Sumatriptan|DRUG: Citalopram|DRUG: Cyclobenzaprine|DRUG: Furosemide|DRUG: Gabapentin|DRUG: Hydrochlorothiazide|DRUG: Hydroxyurea|DRUG: Rosuvastatin|DRUG: Topiramate|DRUG: Trazodone|DRUG: Valganciclovir|DRUG: Venlafaxine|DRUG: Verapamil|DRUG: Remdesivir|DRUG: Anakinra|DRUG: Tocilizumab|DRUG: Fluvoxamine|DRUG: Amoxicillin|DRUG: Bupropion|DRUG: Duloxetine|DRUG: Hydrocodone|DRUG: Levetiracetam|DRUG: Paroxetine|DRUG: Buprenorphine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: AT Versus TP as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer
Status: UNKNOWN
Conditions: HER2-negative Breast Cancer
Interventions: DRUG: AT regimen|DRUG: TP regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of VR in Children With DCD: Randomized Controlled Trial
Status: COMPLETED
Conditions: Virtual Reality|Developmental Coordination Disorder|Visual Perceptual Weakness|Motor Skills Disorders|Sensory Disorder|Executive Dysfunction|Participation, Patient
Interventions: OTHER: virtual reality|OTHER: conventional occupational therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening
Status: COMPLETED
Conditions: Pain|Colorectal Adenomas|Colorectal Cancer
Interventions: OTHER: Air Insufflation method.|OTHER: Water Immersion method.|OTHER: Water Exchange method.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Infliximab in Refractory Uveitis in Behcet's Disease: A Safety and Efficacy Clinical Study
Status: COMPLETED
Conditions: Behçet's Disease|Uveitis
Interventions: DRUG: Intravitreal Infliximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Tecnis Multifocal IOL|DEVICE: crystalens Accommodating IOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-center, Retrospective Analysis of Clinical Character, Outcome and Prognosis of Lymphoepithelioma-like Carcinoma
Status: UNKNOWN
Conditions: Lymphoepithelioma-Like Carcinoma|Lymphoepithelioma-Like Carcinoma of Thymus|Lung Cancer
Interventions: OTHER: Non-intervention research
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis
Status: RECRUITING
Conditions: Multiple Sclerosis|Major Depressive Disorder
Interventions: BEHAVIORAL: POWER-MS|BEHAVIORAL: FLEX-MS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol
Status: TERMINATED
Conditions: Elevated LDL Cholesterol
Interventions: DRUG: Cardiovascular fixed dose combination pill (acetylsalicylic acid, simvastatin and ramipril)|DRUG: Simvastatin, ramipril, acetylsalicylic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Physical Training, ASA (Aspirin), and Clopidogrel on the Walking Capacity of Patients With Stage II Peripheral Arterial Disease (PAD)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fexofenadine HCl 180 mg, Montelukast Sodium 10 mg and Placebo in Suppression of Wheal and Flare Induced by Seasonal Allergen
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: DRUG: Fexofenadine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Oxaliplatin and Docetaxel as First-line Therapy for Advanced Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Oxaliplatin + Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inhaled Salbutamol in Elective Caesarean Section
Status: UNKNOWN
Conditions: Postnatal Pulmonary Adaptation|Cesarean Section
Interventions: DRUG: salbutamol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison Study of Basal Bolus Therapies Together With Lispro Insulin in Type 2 Diabetes Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Glargine|DRUG: Insulin Lispro Protamine Suspension (ILPS)|DRUG: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Pharmacokinetics of ASP2151 in Healthy Non-elderly and Elderly Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: ASP2151|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of the Education Program on Increasing the Competency Level of Health Cadres in Indonesia
Status: NOT_YET_RECRUITING
Conditions: Maternal Mortality
Interventions: OTHER: The education program|OTHER: the initial orientation from the PHCs
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Natural History of Carotid Plaque as Determined by 3D Ultrasound
Status: UNKNOWN
Conditions: Atherosclerotic Disease|Plaque, Atherosclerotic|Heart Diseases|Stroke|Cardiovascular Risk Factor
Interventions: DEVICE: Ultrasound 3D Imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Iron-Biofortified Rice Intervention in the Philippines
Status: COMPLETED
Conditions: Iron-deficiency|Anemia
Interventions: OTHER: Iron-biofortified rice|OTHER: Control rice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Electro-Acupuncture Therapy for Patients With Methadone Maintenance Treatment
Status: UNKNOWN
Conditions: Sleep Disorder (Disorder)
Interventions: PROCEDURE: electroacupuncture+auricular pressure,
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively
Status: COMPLETED
Conditions: Influenza Immunization|Healthy Volunteers
Interventions: BIOLOGICAL: Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2021-2022 formulation|BIOLOGICAL: Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2021-2022 formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial of VELCADE in Patients With Metastatic or Locally Recurrent Nasopharyngeal Carcinoma
Status: WITHDRAWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Velcade
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crossover Study to Compare Pharmacokinetic Property of SYP-1512 Tab and Revlimid Cap in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy, Male
Interventions: DRUG: SYP-1512|DRUG: Revlimid cap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer
Status: TERMINATED
Conditions: Small Cell Lung Cancer
Interventions: DRUG: ADI-PEG 20 (Arginine deiminase pegylated)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors
Status: TERMINATED
Conditions: Hematologic Malignancies|Solid Tumor
Interventions: DRUG: PF-0791800 (TTI-621)|DRUG: PF-07901800 (TTI-621) plus Rituximab|DRUG: PF-07901800 (TTI-621) plus Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pancreatic Duct Stent for Acute Necrotizing Pancreatitis
Status: COMPLETED
Conditions: Necrotizing Pancreatitis|Walled Off Necrosis
Interventions: DEVICE: Pancreatic Duct Stent Placement|OTHER: No Pancreatic Duct Stent Placement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Interaction Study Between JNJ-54861911 and Transporter Substrates Rosuvastatin and Metformin in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosuvastatin|DRUG: JNJ-54861911|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Efficacy of MK-8998 in Acutely Psychotic Participants With Schizophrenia (MK-8998-004)
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: MK-8998|DRUG: Comparator: Olanzapine|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Compare the Pharmacokinetics of Dipyridamole in Three Different Asasantin Extended Release (ER) Formulations in Healthy Male and Female Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Asasantin ER, new formulation I|DRUG: Asasantin ER, new formulation II|DRUG: Asasantin ER, present commercial formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: The Safety and The Efficacy Evaluation of NEUROSTEM®-AD in Patients With Alzheimer's Disease
Status: COMPLETED
Conditions: Dementia of the Alzheimer's Type
Interventions: BIOLOGICAL: Human Umbilical Cord Blood Derived-Mesenchymal Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm
Status: COMPLETED
Conditions: Chronic Myelomonocytic Leukemia-2|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: Cytarabine|DRUG: Decitabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Learn if Different Doses of REGN7544 Are Safe in Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: REGN7544|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: This Study is to Assess the Efficacy and Safety of ZD6474 in Subjects With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms|Metastases, Neoplasm
Interventions: DRUG: ZD6474
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anterior Cruciate Ligament Injury Prevention Protocol in Female Football Players With Dynamic Knee Valgus
Status: NOT_YET_RECRUITING
Conditions: Anterior Cruciate Ligament Injuries
Interventions: OTHER: Application of an anterior cruciate ligament injury prevention protocol for female football players with dynamic knee valgus for 12 weeks.|OTHER: Placebo - Conventional fitness programme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Feasibility Study to Evaluate Adjuvant Chemoradiotherapy for Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: epirubicin|DRUG: cisplatin|DRUG: 5-fluorouracil|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of 3% Diquafosol Ophthalmic Solution on Visual Display Terminal-associated Dry Eye
Status: UNKNOWN
Conditions: Dry Eye Syndromes|Computer Vision Syndrome|Asthenopia
Interventions: DRUG: Diquafosol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial
Interventions: DRUG: Montelukast|DRUG: Comparator: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The RETRIEVE Study: Use of the FiberNet® Embolic Protection System in Saphenous Vein Grafts
Status: COMPLETED
Conditions: Saphenous Vein Graft Disease|Myocardial Ischemia|Embolism
Interventions: DEVICE: FiberNet EPS used during SVG intervention.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Tegafur-uracil (UFT) Versus Sorafenib as First Line Systemic Treatment for Patients With Advanced Stage HCC, Unresectable & Not Eligible for Local Ablation and/or TACE
Status: TERMINATED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Sorafenib|DRUG: sorafenib plus tegafur-uracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Person-Centred Information and Communication for Patients Undergoing Colo-Rectal Surgery - the PINCORE Project
Status: COMPLETED
Conditions: Colorectal Neoplasms
Interventions: OTHER: person-centred communication
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of ARI-3037MO, to Suppress LDL Cholesterol in Patients With Dyslipidemia
Status: UNKNOWN
Conditions: Hyperlipidemia
Interventions: DRUG: ARI-3037MO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure
Status: UNKNOWN
Conditions: Fissure in Ano|Rectal Diseases|Rectal Bleed
Interventions: DRUG: 2% Diltiazem ointment with 1.5% lidocaine|DRUG: 0.3% Nifedipine ointment with 1.5% lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Chimerism in MDS or AML Patients After Allogeneic Stem Cell Transplant
Status: RECRUITING
Conditions: Myeloid Malignancy
Interventions: DRUG: azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of a Selective Chest Wall Restriction Belt in Postoperative of Lung Resection
Status: COMPLETED
Conditions: Lung Cancer
Interventions: PROCEDURE: Conventional follow-up|DEVICE: Conventional follow-up+chest wall restriction belt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hypofractionated Versus Single Fraction Stereotactic Adjuvant Radiotherapy to the Resection Cavity of Brain Metastases
Status: RECRUITING
Conditions: Brain Metastases|Resection Cavity
Interventions: RADIATION: Hypofractionated stereotactic radiotherapy (HFSRT) versus single fraction stereotactic radiotherapy radiosurgery (SRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caffeine and Hypoxia During Exercise in Males and Females
Status: COMPLETED
Conditions: Caffeine|Hypoxia
Interventions: DIETARY_SUPPLEMENT: Caffeine|OTHER: Hypoxia|OTHER: Placebo|OTHER: Normoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Platelet Enzymatically Oxidized Phospholipids (eoxPL) Characterisation in a Healthy Cohort on and Off Aspirin
Status: COMPLETED
Conditions: Platelet Dysfunction Due to Aspirin
Interventions: DRUG: Aspirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Recombinant Human Endostatin Combined With NP in Neoadjuvant Chemotherapy of Stage ⅢA NSCLC
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Endostatin|DRUG: Vinorelbine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thread Lifting and Microfocused Ultrasound for Face Tightening Ultrasound for Lifting and Tightening the Face
Status: UNKNOWN
Conditions: Skin Lifting and Tightening
Interventions: DEVICE: HIFU device (Doublo, HIRONIC Co., Sungnam, Korea)|DEVICE: Threads used in this study are absorbable Aptos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mirror Therapy on Pain and Function on Bilateral Carpal Tunnel Syndrom
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Mirror therapy|OTHER: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Blood Levels, Safety, and Tolerability of PF-00734200 in Subjects With Impaired Kidney Function and Normal Kidney Function
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: PF-00734200
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D Ultrasound Breast Imaging
Status: RECRUITING
Conditions: Breast Tumor
Interventions: DIAGNOSTIC_TEST: GE Logiq E10 clinical ultrasound scanner|DIAGNOSTIC_TEST: Verasonics research scanner
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Stenosis|Symptomatic Aortic Stenosis|Aortic Regurgitation
Interventions: DEVICE: SAPIEN 3 THV with the Commander delivery system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Papillomavirus (HPV) Vaccine Consistency and Non-inferiority Trial in Young Adult Women
Status: COMPLETED
Conditions: Papillomavirus Type 16/18 Infection|Cervical Intraepithelial Neoplasia
Interventions: BIOLOGICAL: Cervarix™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Anaplastic Large Cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Adult Diffuse Mixed Cell Lymphoma|Recurrent Adult Diffuse Small Cleaved Cell Lymphoma|Recurrent Adult Immunoblastic Large Cell Lymphoma|Recurrent Adult Lymphoblastic Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: cyclophosphamide|DRUG: etoposide|RADIATION: iodine I 131 tositumomab|PROCEDURE: quality-of-life assessment|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DECT Ventilation Imaging
Status: TERMINATED
Conditions: For Oncologic Patients|Potentially Operable Lung Tumor|With a Recent (Less Than 1 Month) VQ Scan|For Lung Transplant Recipients|Single of Bilateral Lung Transplant|From 5 Months Onwards|With Recent (Less Than 1 Month) Respiratory Functional Explorations
Interventions: RADIATION: Single source dual energy compted tomography (CT750HD, General Electric, USA) with Krypton as a gaseous contrast media
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Intra-cuff Lidocaine and Tetracaine on Tracheal Tube-induced Emergence Phenomena
Status: COMPLETED
Conditions: Pharyngitis
Interventions: DRUG: 2% lidocaine|DRUG: placebo|DRUG: 1% tetracaine|DRUG: N.S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuing Versus Withdrawing Adalimumab in Maintaining Remission in Non-Radiographic Axial Spondyloarthritis
Status: COMPLETED
Conditions: Axial Spondyloarthritis
Interventions: BIOLOGICAL: adalimumab|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Congenital Adrenal Hyperplasia|21-Hydroxylase Deficiency|Adrenogenital Syndrome
Interventions: DRUG: Chronocort|DRUG: Cortef
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Up To Me: Erasing the Stigma of Mental Illness on College Campuses
Status: UNKNOWN
Conditions: Mental Illness|Behavior Disorders|Severe Mental Illness|Psychiatric Diagnosis|Psychiatric Diseases|Psychiatric Disorders|Psychiatric Illness
Interventions: BEHAVIORAL: Up To Me Intervention + No Booster|BEHAVIORAL: Up To Me Intervention + Booster
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of Fast-track Perioperative Program After Liver Resection in Hong Kong Chinese Patients
Status: RECRUITING
Conditions: Liver Cancer
Interventions: OTHER: Fast-track peri-operative program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of PR Efficiency in Home-based With Hospital-based PR in Bronchiectasis
Status: RECRUITING
Conditions: Bronchiectasis|Pulmonary Rehabilitation|Lung Diseases|Lung Diseases, Interstitial
Interventions: OTHER: Hospital-based pulmonary rehabilitation|OTHER: Home-based pulmonary rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Safety and Efficacy of a Monoclonal Antibody to Treat Influenza
Status: WITHDRAWN
Conditions: Influenza
Interventions: DRUG: Oseltamivir|BIOLOGICAL: MEDI8852|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Deficiency and Vitamin D Supplementation on Glucose Metabolism
Status: COMPLETED
Conditions: Prediabetes|Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Cholecalciferol (vitamin D3)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of the Safety and Efficacy of C019199 Plus Sintilimab in Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: C019199|DRUG: Sintilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT