pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A 12-week Study to Assess the Efficacy and Safety of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler in Participants With Inadequately Controlled Asthma (LITHOS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Asthma
Interventions: DRUG: BFF MDI 160/9.6 μg BID (320/19.2μg/day)|DRUG: BD MDI 160 μg BID (320 μg/day)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Peroral Endoscopic Myotomy Versus Botulinum Toxin Injection in Spastic Esophageal Disorders
Status: WITHDRAWN
Conditions: Esophageal Achalasia|Esophageal Spasm, Diffuse|Esophageal Motility Disorders
Interventions: PROCEDURE: peroral endoscopic myotomy|PROCEDURE: Botulinum toxin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 2- Day vs. 5- Day Terlipressin and Ceftriaxone in the Control Acute Gastroesophageal Variceal Hemorrhage
Status: UNKNOWN
Conditions: Variceal Rebleeding Rate and Infections
Interventions: DRUG: Terlipressin 1Mg Powder for Conventional Release Solution for Injection Vial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Glioblastoma
Interventions: DRUG: IDO1 Inhibitor BMS-986205 25mg|DRUG: Nivolumab|RADIATION: Radiation Therapy|DRUG: Temozolomide|DRUG: IDO1 Inhibitor BMS-986205 50 mg|DRUG: IDO1 Inhibitor BMS-986205 100 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Gantenerumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Cohort Study of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine in Participants Aged 18 Years and Over in Chinese People
Status: UNKNOWN
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine low dose|BIOLOGICAL: SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine high dose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1b Combo w/ Ribociclib and Alpelisib
Status: RECRUITING
Conditions: Metastatic Breast Cancer|Advanced Breast Cancer|HR-positive Breast Cancer|HER2-negative Breast Cancer
Interventions: DRUG: OP-1250|DRUG: Ribociclib|DRUG: Alpelisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the SIMBA Capsule for Small Intestinal Dysbiosis
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Crohn Disease|Celiac Disease|Ulcerative Colitis|Functional Dyspepsia
Interventions: DEVICE: fluid biopsy capsule
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Arsenic Trioxide and Cholecalciferol (Vitamin D) in Treating Patients With Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Leukemia|Myelodysplastic Syndromes|Myelodysplastic/Myeloproliferative Neoplasms
Interventions: DIETARY_SUPPLEMENT: cholecalciferol|DRUG: arsenic trioxide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nociception and BIS Level Monitoring in COVID-19 Patients in the Intensive Care Unit
Status: COMPLETED
Conditions: Nociceptive Pain
Interventions: DEVICE: Nociception Level Monitor (NOL) by Medasense Biometrics Ltd., Israel|DEVICE: Bispectral index (BIS)|OTHER: Questionnaire perception of the nurse on pain patient
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telemedicine Enhanced Asthma Management - Uniting Providers
Status: RECRUITING
Conditions: Asthma in Children
Interventions: OTHER: TEAM-UP Intervention Group|OTHER: Enhanced Care Comparison
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Interscalene Nerve Block vs. Sedation for Shoulder Dislocation Reduction
Status: UNKNOWN
Conditions: Shoulder Dislocation|Brachial Plexus Block
Interventions: DRUG: Lidocaine|PROCEDURE: US guided ISCB|DRUG: Midazolam|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Functional Assessment and Pathogenesis of Morquio A
Status: RECRUITING
Conditions: Mucopolysaccharidosis IV Type A|Morquio A Syndrome|MPS IVA
Interventions: DIAGNOSTIC_TEST: Imaging, gait analysis, growth, joint test, hearing test, questionnaire, etc.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: 7-Day, Multi-Site Study of an Investigational Multi-Purpose Disinfecting Solution for Contact Lens Wearers
Status: COMPLETED
Conditions: Contact Lens Care
Interventions: DEVICE: FID 114675A Multi-Purpose Disinfecting Solution (MPDS)|DEVICE: Etafilcon A contact lens (ACUVUE® 2™)|DEVICE: Senofilcon A contact lens (ACUVUE® OASYS™)|DEVICE: Lotrafilcon B contact lens (O2 OPTIX®)|DEVICE: Balafilcon A contact lens (PureVision®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Transplantation of Autologous Peripheral Blood Mononuclear Cells for Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: PBMC autotransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Forms of Transcutaneous Electrical Stimulation in Overactive Bladder
Status: UNKNOWN
Conditions: Overactive Bladder|Urinary Urge Incontinence
Interventions: DEVICE: Parasacral Transcutaneous Electrical Stimulation|DEVICE: Transcutaneous Posterior Tibial Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: AIDI - Research & Development of a Multisensor-Based Machine Learning Technology for Real-Time Automated Detection of COVID-19 Decompensation
Status: WITHDRAWN
Conditions: Sars-CoV-2 Infection
Interventions: DEVICE: Monitoring of vital signs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Salvage Therapy With High Dose Oral Clarithromycin in Relapsed or Refractory Extranodal Marginal Zone Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: clarithromycin, oral, high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture and Auditory Evoked Potentials
Status: COMPLETED
Conditions: Evoked Potentials|Healthy Volunteers
Interventions: BEHAVIORAL: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Surgical Approach in Hemiarthroplasty. A Randomized Clinical Trial Comparing Posterior and Anterior Approach
Status: RECRUITING
Conditions: Femoral Neck Fractures|Bone Mineral Density|Muscle Damage|Surgical Approach
Interventions: PROCEDURE: Posterior SPAIRE approach, anterior approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Can Diabetes Distress be Reduced by Improving Entry to Care for Type 2 Diabetes Patients
Status: RECRUITING
Conditions: Type 2 Diabetes|Diabetes Distress
Interventions: OTHER: four core components care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluationn of Tolerability and Safety of CBT101, an Autologous Natural Killer Cell, in Patients With Solid Cancer
Status: COMPLETED
Conditions: Solid Tumor
Interventions: BIOLOGICAL: CBT101 cells, every 2 weeks|BIOLOGICAL: CBT101 cells, every 4 weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Clinical Parameters Associated With the Use of Ryzodeg® (Insulin Degludec/Insulin Aspart) in a Real-world Adult Population With Type 2 Diabetes in South Korea
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Ryzodeg®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Feasibility of a Sprint Interval Training Program During Inpatient Spinal Cord Injury Rehabilitation
Status: ENROLLING_BY_INVITATION
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Sprint Interval Training (SIT)|BEHAVIORAL: Usual Care|BEHAVIORAL: Home Ergometer (ERGO)|BEHAVIORAL: Motivational Interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies
Status: RECRUITING
Conditions: Biochemically Recurrent Prostate Cancer
Interventions: DRUG: Darolutamide (BAY1841788, Nubeqa)|OTHER: Placebo matching darolutamide|OTHER: ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum and Peritoneal Concentration in Antibiotics During the Surgical Management of Peritonitis
Status: UNKNOWN
Conditions: Peritonitis|Critical Illness
Interventions: OTHER: Dosage of serum and peritoneal of the B lactam used for antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety of Two Trivalent Influenza Vaccines Evaluated in Children and Adolescents 4 to 17 Years of Age
Status: COMPLETED
Conditions: Influenza|Fever
Interventions: BIOLOGICAL: Mammalian cell based flu vaccine|BIOLOGICAL: Egg based flu vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma
Status: TERMINATED
Conditions: Mantle Cell Lymphoma|Diffuse Large Cell Lymphoma|Burkitts Lymphoma|T Cell Lymphomas|Acute Myeloid Leukemia/Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: cellular immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUbstrate Ablation in Persistent Atrial Fibrillation for Elimination of Recurrences (SUPAFER).
Status: RECRUITING
Conditions: Persistent and Long Lasting or Chronic Atrial Fibrillation|Atrial Fibrillation Ablation|Linear Left Atrial Ablation|Daily Transtelephonic Electrocardiogram
Interventions: OTHER: Radiofrequency ablation of heart atrial tissue.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Aggressive Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia|Diffuse Large B-Cell Lymphoma|Mantle Cell Lymphoma|Myelodysplastic Syndrome|Myelodysplastic/Myeloproliferative Neoplasm|Prolymphocytic Leukemia|Recurrent Chronic Lymphocytic Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Recurrent Hodgkin Lymphoma|Recurrent Plasma Cell Myeloma|Recurrent Small Lymphocytic Lymphoma|Recurrent Waldenstrom Macroglobulinemia|Hematologic and Lymphocytic Disorder|Blastic Plasmacytoid Dendritic Cell Neoplasm
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Cyclosporine|DRUG: Mycophenolate Mofetil|DRUG: Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Tobacco Control Intervention in African-American Families
Status: COMPLETED
Conditions: Tobacco Prevention|Environmental Tobacco Smoke Exposure|Tobacco Cessation
Interventions: BEHAVIORAL: LifeSkills Training|BEHAVIORAL: Healthy Lifestyle Behavior Choices|BEHAVIORAL: NRT and Motivational Interviewing (MI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Adolescent Health and Wellbeing Check-up Programme in Three African Cities (Y-Check)
Status: RECRUITING
Conditions: Adolescent Development|Adolescent Behavior|Health-Related Behavior|Health Care Seeking Behavior
Interventions: OTHER: Screening package|DIAGNOSTIC_TEST: Psychosocial and mental health disorder screening|DIAGNOSTIC_TEST: Alcohol, tobacco and substance use screening|BEHAVIORAL: Diet and physical activity screening|DIAGNOSTIC_TEST: Underweight and overweight screening|DIAGNOSTIC_TEST: Anemia|BEHAVIORAL: Oral health screening|BEHAVIORAL: Circumcision screening|BEHAVIORAL: Risky behaviours|DIAGNOSTIC_TEST: HIV testing|DIAGNOSTIC_TEST: STI (CT, NG, TV) testing|BEHAVIORAL: Immunization screening|DIAGNOSTIC_TEST: Visual impairment screening|DIAGNOSTIC_TEST: Hearing screening|DIAGNOSTIC_TEST: Physical impairment screening|DIAGNOSTIC_TEST: Uncontrolled epilepsy screening|DIAGNOSTIC_TEST: Pre-hypertension screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects
Status: RECRUITING
Conditions: Stroke|Healthy
Interventions: OTHER: Upper limb pointing movements in 3 experimental conditions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Clinical Study of MIL62 in Systemic Lupus Erythematosus
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: MIL62|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacology of Exenatide in Pediatric Sepsis
Status: WITHDRAWN
Conditions: Septic Shock|Inflammation|Glucose Homeostasis|Organ Dysfunction|Health-related Quality of Life
Interventions: DRUG: Exenatide|DRUG: Exenatide vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: S0012 Doxorubicin, Cyclophosphamide, and Paclitaxel With or Without Filgrastim in Treating Women With Inflammatory or Locally Advanced Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: doxorubicin|DRUG: paclitaxel|PROCEDURE: surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Safety Extension Study of 5 and 10 mg of Vortioxetine (Lu AA21004) in Long-term Treatment of Major Depressive Disorder in Adults
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine (Lu AA21004)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Efficacy, and Safety of Perampanel Oral Suspension on Seizure Frequency in Pediatric Subjects Maintained on One to Three Stable Antiepileptic Drugs
Status: COMPLETED
Conditions: Central Nervous System
Interventions: DRUG: perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of STABLOR® on Visceral Fat Mass Reduction in Patients With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Stablor|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Etomidate to Improve Outcome in Elderly Patients
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: Etomidate|DRUG: propofol|DRUG: Sufentanil|DRUG: Cisatracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of LY2228820 With Radiotherapy Plus Concomitant TMZ in the Treatment of Newly Diagnosed Glioblastoma
Status: COMPLETED
Conditions: Adult Glioblastoma
Interventions: DRUG: LY2228820|DRUG: Temozolomide|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intralesional 5-Fluorouracil (5FU), Topical Imiquimod Treatment for SCC
Status: RECRUITING
Conditions: Carcinoma, Squamous Cell
Interventions: DRUG: 5-fluorouracil|DRUG: Imiquimod 5% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing a Home-based Virtual Reality Exercise Program for Chronic Stroke Patients: A Telerehabilitation Approach
Status: RECRUITING
Conditions: Stroke
Interventions: OTHER: home written exercise program|OTHER: telerehabilitation/exergame system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Cohort of Children With HIV Infection
Status: ACTIVE_NOT_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Zidovudine, Stavudine, Didanosine, Lamivudine|DRUG: Nevirapine, Efavirenz|DRUG: LPV/r, Saquinavir, Indinavir, Ritonavir, Nelfinavir
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SBRT as a Vaccination for Metastatic Melanoma
Status: WITHDRAWN
Conditions: Metastatic Melanoma
Interventions: DRUG: Nivolumab 10 MG/ML Intravenous Solution [OPDIVO]|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Celecoxib in Treating Patients With Early-Stage Head and Neck Cancer or Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Lung Cancer
Interventions: DRUG: celecoxib|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effects of PBMT-sMF in Mechanically Ventilated Patients
Status: RECRUITING
Conditions: Respiratory Failure
Interventions: DEVICE: Placebo PBMT-sMF|DEVICE: Active PBMT-sMF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
Status: NOT_YET_RECRUITING
Conditions: Degenerative Disc Disease
Interventions: DEVICE: One level Mobi-C and one level fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplantation From Unrelated Donors
Status: RECRUITING
Conditions: Acute Leukemia|Immune Deficiency Disorder|Congenital Hematological Disorder|Metabolism Disorder|Aplastic Anemia|Myelodysplastic Syndromes|Chronic Leukemia|Lymphoma|Multiple Myeloma|Solid Tumor
Interventions: RADIATION: Total Body Irradiation 1200 cGy|RADIATION: Total Body Irradiation 200 cGy|DRUG: Cyclophosphamide|DRUG: Mesna|PROCEDURE: Cord Blood Infusion|DRUG: Busulfan|DRUG: Fludarabine|DRUG: Melphalan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Movantik for Opioid-Related Esophageal Disorders
Status: TERMINATED
Conditions: Opioid-Induced Disorders|Esophagus Disorder
Interventions: DRUG: Naloxegol|DRUG: Placebo Oral Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ropivacaine Combined With Different Concentrations of Methylene Blue Fascia Iliaca Block in Postoperative Analgesia, Cognition, and Hip Function Recovery in Patients Undergoing Hip Arthroplasty
Status: ENROLLING_BY_INVITATION
Conditions: Femoral Neck Disease
Interventions: DRUG: Ropivacaine combined with methylene blue for iliac fascia block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Allogeneic MSC Treatment for Pulmonary Emphysema
Status: UNKNOWN
Conditions: Pulmonary Emphysema|Mesenchymal Stromal Cells
Interventions: GENETIC: Allogeneic MSC|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Gastroesophageal-junction Cancer|Monoclonal Antibody|Gastric Cancer|HER2-positive Gastric Cancer
Interventions: DRUG: HLX22|DRUG: Pembrolizumab|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A D1 Agonist For Working Memory
Status: COMPLETED
Conditions: Schizotypal Personality Disorder|SPD
Interventions: DRUG: DAR 0-100A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Photodynamic Therapy With Verteporfin for Corneal Neovascularization
Status: COMPLETED
Conditions: Corneal Neovascularization
Interventions: PROCEDURE: Photodynamic Therapy with Verteporfin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short and Long-term Effects of Adding Oral L-arginine to Standard Therapy in Patients With COVID-19 (SARS-CoV-2)
Status: UNKNOWN
Conditions: Covid19
Interventions: DIETARY_SUPPLEMENT: Bioarginina®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study of B/F/TAF in Participants Switching From CAB + RPV to B/F/TAF for HIV-1 Infection (EMPOWER)
Status: RECRUITING
Conditions: HIV-1-infection
Interventions: DRUG: B/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)
Status: RECRUITING
Conditions: Lung Neoplasms
Interventions: DEVICE: Transbronchial Microwave Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Manuka Honey Oral Rinse in Treatment of Xerostomia
Status: COMPLETED
Conditions: Dry Mouth|Salivary Gland Diseases
Interventions: OTHER: Manuka Honey|OTHER: Saline mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Whole Body Vibration on Spasticity in Persons With Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury|Spasticity
Interventions: DEVICE: Vibration with tilt-table standing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceuticals Ltd.'s Olmesartan Medoxomil Tablets Under Fed Conditions
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Torrent's Olmesartan Medoxomil Tablets 40 mg|DRUG: Daiichi Sankyo Inc's Benicar Tablets 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of a 10% Triple Virally Reduced Intravenous Immune Globulin Solution in Adult Subjects With Chronic Idiopathic Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Immune Thrombocytopenic Purpura (ITP)
Interventions: DRUG: Immune Globulin Intravenous (Human), 10% Triple Virally Reduced Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study to Assess the Absorption, Metabolism, and Excretion of [14C] Labeled SPN-810M
Status: COMPLETED
Conditions: Impulsive Aggression Comorbid With ADHD
Interventions: DRUG: SPN-810M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DRUG: Azithromycin|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment
Status: COMPLETED
Conditions: Rhegmatogenous Retinal Detachment
Interventions: DRUG: Ursodeoxycholic Acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Ramosetron in Prevention of Intrathecal Morphine Induced Nausea and Vomiting
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: ramosetron|DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Porous and Non-porous Bone Grafts in Intra-bony Periodontal Defects
Status: COMPLETED
Conditions: Periodontal Disease
Interventions: DRUG: Porous variant of Bioactive Glass.|DRUG: Non porous variant of Bioactive Glass.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Teneligliptin in Chinese Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Teneligliptin 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigate Dose of Org 36286 to Initiate Multiple Follicular Growth in a Controlled Ovarian Hyperstimulation Protocol for IVF or IVF/ICSI (P07015)
Status: COMPLETED
Conditions: Infertility|In Vitro Fertilization
Interventions: DRUG: Org 36286|DRUG: Puregon®|DRUG: Orgalutran®|DRUG: Pregnyl®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Placebo in the Treatment of Mania in Adolescents With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Olanzapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hinged Versus Conventional 8 Plate for Correction of Genu Valgum or Varum
Status: UNKNOWN
Conditions: Genu Valgum or Varum|Growth; Arrested, Bone|Epiphyseal Arrest, Lower Leg
Interventions: DEVICE: hinged 8-figure plate|DEVICE: conventional 8-figure plate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy
Status: UNKNOWN
Conditions: Morbid Obesity
Interventions: PROCEDURE: laparoscopic operation Sleeve Gastrectomy|PROCEDURE: laparoscopic operation Roux-en-Y Gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety and Tolerability of PCI-27483 in Patients With Pancreatic Cancer Patients Receiving Treatment With Gemcitabine
Status: COMPLETED
Conditions: Pancreatic Cancer|Ductal Adrenocarcinoma|Exocrine Pancreatic Cancer
Interventions: DRUG: PCI-27483|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Following an Episode of Pre-eclampsia Using a Dissociated or Hypocaloric Diet in Overweight or Obese Patients
Status: RECRUITING
Conditions: Pre-Eclampsia|Obesity
Interventions: OTHER: Hypocaloric diet|OTHER: Dissociated diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Comparison of Peak Aqueous Penetration of Acuvail (Ketorolac 0.45%), Xibrom (Bromfenac 0.09%), and Nevanac (Nepafenac 0.1%)in Patients Undergoing Phacoemulsification
Status: COMPLETED
Conditions: Cataracts
Interventions: DRUG: Ketorolac Tromethamine 0.45%|DRUG: bromfenac 0.09%|DRUG: nepafenac 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adagrasib + SRS for Patients With Metastatic KRAS G12C-mutated NSCLC With Untreated Brain Metastases
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|NSCLC|KRAS G12C
Interventions: DRUG: Adagrasib|RADIATION: Stereotactic Radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Propofol/Alfentanil With Propofol/Ketamine
Status: UNKNOWN
Conditions: Lung Disease
Interventions: DRUG: Propofol|DRUG: Ketamine|DRUG: Alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Topical Diclofenac Gel in Patients With Superficial Inflammation of the Veins
Status: COMPLETED
Conditions: Superficial Thrombophlebitis of the Upper Limb
Interventions: DRUG: Diclofenac gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Accuracy of Deep Inferior Epigastric Artery Perforator Mapping - Color Doppler Ultrasound Versus CT Angiography
Status: COMPLETED
Conditions: Mammaplasty
Interventions: PROCEDURE: Colour Doppler Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selective Cerebral Hypothermia Trial - Under Extracorporeal Cardiopulmonary Resuscitation (SHOT-ECPR)
Status: UNKNOWN
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: PROCEDURE: Selective cerebral hypothermia|PROCEDURE: Regular hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAFE (Sarpogrelate Anplone in Femoro-popliteal Artery Intervention Efficacy) Study
Status: UNKNOWN
Conditions: Peripheral Arterial Disease
Interventions: DRUG: Sarpogrelate SR 300mg|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis
Status: RECRUITING
Conditions: Peritonitis|Sepsis|Septic Shock
Interventions: DRUG: Pentaglobin®/Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer Stage IIB
Interventions: DRUG: Hydroxychloroquine|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Surgery
Status: COMPLETED
Conditions: Lactate Blood Increase|Fluid Overload|Postoperative Complications
Interventions: OTHER: Applying goal-directed fluid therapy by continuous hemodynamic monitoring system (LiDCO）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Double-blind, Active Control, Parallel Group, Titration, Multicenter Study to Evaluate the Efficacy and Safety of Fimasartan
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Fimsartan 60mg~120mg|DRUG: Fimsartan 60mg~120mg|DRUG: Losartan 50mg~100mg|DRUG: Losartan 50mg~100mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrating a Stepped Care Model of Screening and Treatment for Depression Into Malawi's National HIV Care Delivery Platform
Status: ACTIVE_NOT_RECRUITING
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Problem Management Plus|DRUG: Antidepressant Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Turmeric Based Therapy in the Treatment of Psoriasis: A Clinical Trial
Status: UNKNOWN
Conditions: Psoriasis
Interventions: DRUG: Turmeric Extract|DRUG: Turmeric Extract in Olive oil|DRUG: Petrolatum|DEVICE: NB-UVB|DRUG: calcipotriol/ Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation of Laser Lancing Devices in Adult Type 2 Diabetes Patients
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DEVICE: laser lancing device or lancet for blood glucose level measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase Ib/II Clinical Study of HRS-1167 in Combination With Bevacizumab in Patients With Recurrent Ovarian Cancer
Status: RECRUITING
Conditions: Recurrent Ovarian Cancer
Interventions: DRUG: Bevacizumab； HRS-1167
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Randomized, Double-Blind, Placebo-Controlled, Parallel Design, Multicenter Trial to Evaluate the Effect of Ranitidine on Immunologic Indicators in Asymptomatic HIV-1 Infected Subjects With a CD4 Cell Count Between 400-700 Cells/mm3
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Ranitidine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Pharmacokinetics and Tolerability of CKD-348
Status: COMPLETED
Conditions: Hypertension and Dyslipidemia
Interventions: DRUG: CKD-348|DRUG: CKD-828, D097, D337
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Subcutaneous and Intraperitoneal Anesthesia on Post Laparoscopic Pain
Status: COMPLETED
Conditions: Varicocele|Postoperative Pain
Interventions: DRUG: 2% Lidocaine|DRUG: 0.5% levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Technosphere® Insulin Inhalation Powder (TI Inhalation Powder)When an Optimal Dose is Taken With Varied Carbohydrate Intake
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2|Diabetes Mellitus, Type 1
Interventions: DRUG: TI Inhalation Powder and Humalog (Amendment 1)|DRUG: TI Inhalation Powder (original protocol)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dabrafenib Plus Trametinib in Patients With Advanced Solid Tumor Having BRAF V600E Mutation or Clinically Actionable BRAF Gene Alterations
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective, Single-arm, Multicenter Clinical Study on Haploidentical Hematopoietic Stem Cell Transplantation in Patients With MRD Positive CD19+ALL Treated With Conditioning Regimens Containing Blinatumomab
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pre-genotype NUDT 15 R139C on Reducing Thiopurine-induced Leucopenia in Inflammatory Bowel Disease
Status: UNKNOWN
Conditions: Thiopurine-induced Leukopenia
Interventions: GENETIC: Pre-genotype NUDT15 and optimize azathioprine dosage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Tack Optimized Drug Coated Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Tack Endovascular System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Management of Severely Atrophied Maxillary Ridge Using Quad Zygomatic Implants
Status: ACTIVE_NOT_RECRUITING
Conditions: Prosthesis Durability
Interventions: DEVICE: Implant supported hybrid maxillary prosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Bezafibrate 400 mg and Bezafibrate 200 mg as Adjunctive Treatments in Patients With Primary Biliary Cholangitis and Non-optimal Biochemical Response to Ursodeoxycholic Acid Therapy
Status: NOT_YET_RECRUITING
Conditions: BPC|Non Optimal Response to UDCA
Interventions: DRUG: Bezafibrate 400 mg in addition to UDCA therapy|DRUG: Bezafibrate 200 mg in addition to UDCA therapy|DRUG: Placebo in addition to UDCA therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Individualized Homeopathic Treatment in Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis
Interventions: DRUG: homeopathic medicine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resveratrol in Metabolic Syndrome: Effect on Platelet Hyper-reactivity and HDL Lipid Peroxidation
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Resveratrol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: HYCAMTIN, oral capsules|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Wearable-enabled Intervention for Promoting Physical Activity in People Knee OA
Status: COMPLETED
Conditions: Knee Osteoarthritis|Joint Diseases
Interventions: BEHAVIORAL: Education session, Fitbit Flex, and remote coaching by a PT|BEHAVIORAL: Same intervention with a 1 month delay
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Compliance With a High Energy Content, Low Volume Oral Nutritional Supplement
Status: COMPLETED
Conditions: Malnutrition
Interventions: DIETARY_SUPPLEMENT: High-Energy, Low-Volume ONS|DIETARY_SUPPLEMENT: High-Energy Standard ONS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Of Celecoxib Test Formulations
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Celebrex capsule|DRUG: Test formulation D1|DRUG: Test formulation D2|DRUG: Test formulation D3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Aortic Root Dimension Changes During Cardiac Cycle Between the Patients With and Without Aortic Valve Calcification Using ECG-gated 64-slice and Dual-source 256-slice Computed Tomography Scanners: Results of a Multicenter Study
Status: COMPLETED
Conditions: Aortic Valve Calcification
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Analysis of Kinesio® Tape on Myofascial Pain Syndrome of the Iliotibial Band
Status: COMPLETED
Conditions: Myofascial Trigger Point Pain
Interventions: OTHER: Kinesio® Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer
Status: RECRUITING
Conditions: Urinary Urge Incontinence|Stress Urinary Incontinence|Prostatic Hyperplasia
Interventions: DEVICE: Elidah Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment the Efficacy of Acetyl-L-carnitine in Patient With Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Acetyl-L-Carnitine|DRUG: Placebo of Acetyl-L-Carnitine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thymalfasin and Recombinant Human IL-2 Injections in Treating Lymphocytopenia for Patients With Malignant Hematological Tumors
Status: RECRUITING
Conditions: Hematological Malignancy|Lymphocytopenia
Interventions: DRUG: Combination Therapy Group|DRUG: Monotherapy Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Determine the Dose of Recombinant Human Hyaluronidase Needed to Infuse a Full Dose of IGIV Subcutaneously
Status: COMPLETED
Conditions: Primary Immunodeficiency Diseases (PID)
Interventions: BIOLOGICAL: Recombinant human hyaluronidase + immune globulin intravenous|BIOLOGICAL: Recombinant human hyaluronidase + immune globulin intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of COVID-19 Lockdown in Exercising Early Postmenopausal Women
Status: COMPLETED
Conditions: Exercise|Detraining|Muscle Weakness|Muscle Atrophy
Interventions: OTHER: HIT-exercise|OTHER: Sham intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Seprafilm® for Prevention of Adhesions at Repeat Cesarean
Status: TERMINATED
Conditions: Adhesion Formation After Primary Cesarean Delivery
Interventions: DEVICE: Seprafilm®|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability
Status: TERMINATED
Conditions: Chronic Fatigue Syndrome|Intensive Care Unit|Muscle
Interventions: OTHER: Questionnaires|BIOLOGICAL: blood test|OTHER: Maximal effort test|DEVICE: actigraphy|DEVICE: Neuromuscular evaluation|OTHER: stool analysis|OTHER: food diary
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Targeted Resection of Axillary Metastatic Lymph Nodes After Breast Cancer Neoadjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Surgery|Lymph Node Metastases
Interventions: DEVICE: Tissue Marker Clip|DRUG: Carbon Nanoparticle Suspension Injection|DRUG: Carbon Nanoparticle Suspension Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT