pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Bioequivalence of Telmisartan / HCTZ of Fixed Dose Combination Compared to Its Monocomponents in Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Telmisartan|DRUG: Hydrochlorthiazide (HCTZ)|DRUG: Telmisartan/HCTZ fixed dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine on Pain Relief and IL and Substance P in Fibromyalgia
Status: UNKNOWN
Conditions: Fibromyalgia
Interventions: DRUG: Lidocaine|DRUG: lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With High-Grade Lymphoma or Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: etoposide|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neuropsychological Impact of Hospitalization on Intubated, Ventilated and Sedated ICU Patients
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic|Depression
Interventions: OTHER: Baseline activities|OTHER: Clinical interview with a psychologist|OTHER: Telephone interview 2 months after ICU discharge|OTHER: Clinical interview with a psychologist
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Pelvic Floor Therapy and Yoga on Stres Urinary Incontinence Incontinence
Status: UNKNOWN
Conditions: Urinary Incontinence|Urinary Tract Disorders
Interventions: PROCEDURE: Pelvic floor Physical Therapy|PROCEDURE: Therapeutic Yoga Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Roflumilast in Hospitalized Chronic Obstructive Pulmonary Disease( COPD) on Mortality and Re-hospitalization
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: Roflumilast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Toe-spread-out Exercise in Patients With Hallux Valgus and Without the Deformity
Status: COMPLETED
Conditions: Hallux Valgus
Interventions: OTHER: toe-spread-out exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PDL Anesthesia Versus Local Infiltration
Status: COMPLETED
Conditions: Anesthesia, Local
Interventions: PROCEDURE: PDL anesthesia versus local infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Harnessing the Power of Technology: MOMBA for Postpartum Smoking
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: MoMba Live Long app & Sensordrone™ carbon-monoxide sensor|BEHAVIORAL: Office contingency management|DEVICE: Sensordrone™ carbon-monoxide sensor|DEVICE: MoMba Live Long Smartphone application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mat Pilates Method in the Treatment of Women With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia, Primary
Interventions: OTHER: Mat Pilates exercises|OTHER: Aquatic aerobic exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Efficacy of Plant Stanol Esters in Reducing Cholesterol, Medellin 2011
Status: UNKNOWN
Conditions: Risk Reduction Behavior
Interventions: DIETARY_SUPPLEMENT: assessment of efficacy of Benecol yogurt|DIETARY_SUPPLEMENT: Placebo Yogurt|DIETARY_SUPPLEMENT: yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clown Visits in Child and Adolescent Psychiatry
Status: UNKNOWN
Conditions: Subjective Stress|Mood States|Physiological Stress
Interventions: OTHER: Clown visits by RED NOSES Clowndoctors Austria
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Vascular Endothelial Glycocalyx and Ophthalmic Injury, Prospective Cohort of Patients With Prolonged Post-COVID-19 Symptoms
Status: COMPLETED
Conditions: COVID-19|Long COVID
Interventions: PROCEDURE: Ophthalmological examinations|PROCEDURE: GlycoCheck
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First-in-human of Multiplle Doses of BB-1709 in Subjects With Locally Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: BB-1709
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Nasal Steroids in Treatment of Otitis Media With Effusion: Acomparative Study
Status: UNKNOWN
Conditions: Otitis Media With Effusion
Interventions: DRUG: Mometasone Furoate spray|DRUG: prednisolone sodium phosphate 15mg|DRUG: hypertonic sea water solution spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Sarilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation
Status: RECRUITING
Conditions: Lung Transplant
Interventions: PROCEDURE: Off-pump lung transplantation|PROCEDURE: Venoarterial ECMO lung transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Neuroimaging Biomarkers of Social Cognition Deficits in Adolescents (Age 13-17) With Autism Spectrum Disorder and Effects of Gabapentin
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Gabapentin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Role of CT Scan for the Successful Recanalization of Chronic Total Occlusion; a Randomized Comparison Between 3D CT-guided PCI vs. Conventional Treatment (CT-CTO Trial)
Status: UNKNOWN
Conditions: Coronary Artery Obstructive Disease|Chronic Total Occlusion Lesions
Interventions: DEVICE: Pre-PCI coronary CT scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Pharmacokinetics, Safety, and QTc Effect of AG-348 in Healthy Subjects of Japanese Origin and Non-Asian Origin
Status: COMPLETED
Conditions: Healthy|Japanese|Non-Asian
Interventions: DRUG: AG-348|DRUG: AG-348|DRUG: AG-348
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Trial for Asses the Safety and Efficacy of Vitamin C and Vitamin E in Combination Versus Placebo for Treating Cognitive and Behavior Disorder in Children With Fragile X Syndrome
Status: COMPLETED
Conditions: X Fragile Syndrome
Interventions: DRUG: Vitamin C 10mg/Kg Vitamin E 10 mg/Kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-management Intervention for Reducing Epilepsy Burden Among Ugandans With Epilepsy.
Status: NOT_YET_RECRUITING
Conditions: Epilepsy
Interventions: BEHAVIORAL: Self-MAnagement intervention for Reducing The epilepsy burden among Ugandans
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Topical/Oral Melatonin for Preventing Concurrent Radiochemotherapy Induced Oral Mucositis/Xerostomia Cancer Patients
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Melatonin|DRUG: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Several Studys Showed That Upper Limb Amputated Patients Are Able to Experience the Illusion of the Rubber Hand Whith Prosthesis: We Want to go Futher by Comparing the Strength of the Incorporation According to the Type of Prosthesis Using the Illusion of the Rubber Hand With Prothesis
Status: RECRUITING
Conditions: Appropriate Affect
Interventions: OTHER: Modified illusion of the rubber (syncrhone)|OTHER: Modified illusion of the rubber (asynchrone)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DRUG: Caffeine|OTHER: AIH|OTHER: Placebo|OTHER: SHAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Direct Trocar Entry Versus Veress Needle Entry in Laparoscopic Gynecological Surgery
Status: WITHDRAWN
Conditions: Laparoscopic Gynecological Surgery
Interventions: PROCEDURE: Laparoscopic direct entry Trocar|PROCEDURE: Laparoscopic entry Veress needle|DEVICE: Trocar|DEVICE: Veress needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Amino Acid Profile in the Fetus and the Neonate
Status: UNKNOWN
Conditions: Cord Blood Amino Acid Profile|Fetal Amino Acid Profile in Different Gestational Ages|Infant Amino Acid Profile at Day 3 and Discharge
Interventions: OTHER: Blood sample on Guthrie paper from cord blood, and day 3 of life and before discharge
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Glenzocimab for REperfusion in the Setting of Endovascular Therapy for Brain infarctioN: GREEN Study
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute|Stroke, Ischemic
Interventions: DRUG: Glenzocimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Simtuzumab Combined With Gemcitabine for Metastatic Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Simtuzumab|DRUG: Gemcitabine|DRUG: Placebo to match simtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Small Frequent Paracentesis Using an Indwelling CAtheter Compared With Repeated Large Volume Paracentesis in Cirrhotic Patients With REfractory Ascites
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: PROCEDURE: small quantity paracentesis|PROCEDURE: Large Volume Paracentesis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Glucagon Efficiency After High and Low Carbohydrate Diet
Status: COMPLETED
Conditions: Type 1 Diabetes|Hypoglycemia
Interventions: DIETARY_SUPPLEMENT: High carbohydrate intake|DIETARY_SUPPLEMENT: Low carbohydrate intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Two Protocols of Misoprostol (PGE1) and the Rate of Cesarean Section Due to Failed Induction.
Status: COMPLETED
Conditions: Induction of Labor
Interventions: PROCEDURE: 6 misoprostol|PROCEDURE: 3 misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementation of a Multicomponent Intervention to Prevent Physical Restraints in Nursing Home Residents (IMPRINT)
Status: COMPLETED
Conditions: Dementia
Interventions: OTHER: Educational programme for all nurses|OTHER: Training and structured support for nominated key nurses|OTHER: Facultative train-the-trainer module for key nurses|OTHER: Printed study material|OTHER: Supportive material (poster, mugs etc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rein 3D PRINT PERSONALIZE
Status: RECRUITING
Conditions: Tumoral Kidney
Interventions: OTHER: personalized 3D model pré-opérative education|OTHER: generic 3D model pré-opérative education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides
Status: COMPLETED
Conditions: Hypertriglyceridemia|Hyperlipoproteinemia Type IV
Interventions: DRUG: torcetrapib/atorvastatin|DRUG: atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Biological Effects of AZD9833 in Women With ER-positive, HER2 Negative Primary Breast Cancer
Status: COMPLETED
Conditions: HER2-negative Breast Cancer
Interventions: DRUG: AZD9833
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facilitation of NMDA Receptor Function in Patients With Schizophrenia and Co-morbid Alcoholism
Status: COMPLETED
Conditions: Alcoholism|Schizophrenia
Interventions: DRUG: Glycine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fluid Optimization With Crystalloids and Colloids in Neurosurgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: DRUG: Sterofundin (Bolus of crystalloids)|DRUG: Voluven (Bolus of colloids)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of 3 Doses of Crofelemer Compared to Placebo in the Treatment of HIV Associated Diarrhea
Status: COMPLETED
Conditions: HIV Associated Diarrhea
Interventions: DRUG: Crofelemer 125 mg|DRUG: Crofelemer 250 mg|DRUG: Crofelemer 500 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-market Evaluation of Clinical Outcomes in China for the TECNIS Model ZMT
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Study Lens: TECNIS Multifocal Toric 1-piece lens, Model ZMT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of JNJ-67856633 in Participants With Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
Status: ACTIVE_NOT_RECRUITING
Conditions: Leukemia, Lymphocytic, Chronic, B-Cell|Lymphoma, Non-Hodgkin
Interventions: DRUG: JNJ-67856633
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blind, Placebo-Controlled, Phase IIB Trial of Ketorolac Mouth Rinse Evaluating the Effect of Cyclooxygenase Inhibition on Oropharyngeal Leukoplakia: Collaborative Study of the NCI, NIDCD and the NIDCR
Status: COMPLETED
Conditions: Leukoplakia|Periodontal Disease
Interventions: DRUG: Ketorolac Rinse
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Nightly Versus Prn Sildenafil on Early Return of Erectile Function Following Laparoscopic Radical Prostatectomy
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Sildenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Effectiveness of a New Anti-HIV Drug (AG1549) in Combination With Other Anti-HIV Drugs in HIV-Infected Patients
Status: SUSPENDED
Conditions: HIV Infections
Interventions: DRUG: Lamivudine/Zidovudine|DRUG: Capravirine|DRUG: Nelfinavir mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Partical Excavation in One Versus Two Procedures of Primary Deep Caries (PAPRICA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Primary Dental Caries
Interventions: PROCEDURE: Resin restoration (1 step)|PROCEDURE: Resin restoration (2 steps)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different Application Rates of Crisaborole Ointment 2% in Adults With Mild to Moderate Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Crisaborole 2%|DRUG: Placebo ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection
Status: COMPLETED
Conditions: Onchocerciasis
Interventions: DRUG: Moxidectin|DRUG: Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy With Sequential Chemotherapy Combined With PD-1 Inhibitor and Thymalfasin for BRPC
Status: NOT_YET_RECRUITING
Conditions: Carcinoma, Pancreatic Ductal
Interventions: COMBINATION_PRODUCT: SBRT with Sequential AG regimen +Tislelizumab+Thymalfasin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of the Application of PIOMI in the Oral Feeding of Premature
Status: RECRUITING
Conditions: Dysphagia|Disorder; Feeding, Newborn|Premature
Interventions: OTHER: Experimental group PIOMI|OTHER: Control group NIDCAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Levocarnitine|DRUG: Adefovir dipivoxil
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nitrate-based Nutritional Formula for Oxygen Saturation and Patient-reported Outcomes in Covid-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DIETARY_SUPPLEMENT: NITRATE|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone
Status: RECRUITING
Conditions: Maxillary Sinus Floor Augmentation|Dental Implant|Bone Substitute|Autogenous Bone Graft
Interventions: PROCEDURE: Sinus Lift augmentation|DEVICE: Cone-beam computed tomography systems (CBCT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia
Status: TERMINATED
Conditions: Asymptomatic Amyloid-positive
Interventions: DRUG: Atabecestat, 5 mg|DRUG: Atabecestat, 25 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy
Status: UNKNOWN
Conditions: Hypertrophic Cardiomyopathy|Fibrosis
Interventions: DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Intralesional Injection of Plasma Rich Platelets and Candida Antigen in Plane Warts
Status: ACTIVE_NOT_RECRUITING
Conditions: Plane Wart
Interventions: BIOLOGICAL: C. albicans antigen|OTHER: autologous PRP|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: Aldoxorubicin HCl|BIOLOGICAL: ALT-803|BIOLOGICAL: ETBX-011|BIOLOGICAL: GI-4000|BIOLOGICAL: haNK for infusion|BIOLOGICAL: avelumab|BIOLOGICAL: bevacizumab|DRUG: Capecitabine|DRUG: Cyclophosphamide|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: nab-Paclitaxel|DRUG: lovaza|DRUG: Oxaliplatin|PROCEDURE: SBRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Sensitivity and Mutation Profiling
Status: COMPLETED
Conditions: Ewing Sarcoma|Osteosarcoma|Rhabdomyosarcoma|Wilms Tumor|Sarcoma, Spindle Cell|Sarcoma Rhabdoid|Childhood Sarcoma of Soft Tissue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: AT-1965 Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and Cancer Study: Colon Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer of Colon|Anesthesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation
Status: UNKNOWN
Conditions: Cardiovascular Diseases
Interventions: DEVICE: Percutaneous MitraClip Device Implantation|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Laparoscopic Subtotal Gastrectomy With D2 Lymph Node Dissection for Locally Advanced Gastric Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: PROCEDURE: Laparoscopic gastrectomy|PROCEDURE: Open gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)
Status: COMPLETED
Conditions: Pulmonary Artery Hypertension
Interventions: DRUG: GB002 (seralutinib)|DRUG: Placebo|DEVICE: Generic Dry Powder Inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: ADOAIR250 Anti-inflammatory Effects in Japanese Subjects With Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: ADOAIR250|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety and Immunogenicity of a Pandemic Influenza Vaccine in Adults Aged 18 Years and Above
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Adjuvanted pandemic influenza candidate vaccine|BIOLOGICAL: Fluarix|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Glucose-dependent Insulinotropic Polypeptide as a Safeguard Against Hypoglycemia in Patients With Type 1 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: glucose-dependent insulinotropic peptide|DRUG: Glucose-Dependent Insulin-Releasing Hormone[3-30]|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pharmacological and Behavioral Treatment After Bariatric Surgery
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Naltrexone and Bupropion Combination|BEHAVIORAL: Behavioral Weight Loss|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Pen Systems in Patients With Diabetes Treated With Insulin
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 1|Diabetes Mellitus, Type 2|Delivery Systems
Interventions: DEVICE: NovoPen™ 4|DEVICE: NovoPen® 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Animal Assisted Therapy Program in People With Mental Illness, and Promotion of Positive Mental Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Mental Disorders, Severe
Interventions: OTHER: Animal Assited therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Small-dose Dexmedetomidine Effects on Recovery Profiles of Supratentorial Tumors Patients From General Anesthesia
Status: UNKNOWN
Conditions: Brain Neoplasms|Surgery
Interventions: DRUG: dexmedetomidine|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Fu Zheng Jie Du Hua Yu Principle For Treatment Of Severe HBV Related Hepatocellular Carcinoma (FZJDHYPFTOSHBVHCC)
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Fu Zheng Jie Du Hua Yu therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
Status: COMPLETED
Conditions: Autism
Interventions: DRUG: Memantine - Extended Release (ER)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Crossover Feasibility Study of Portable AP Device With Zone-MPC and HMS and Adapted I:C and Basal Insulin
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: portable Artificial Pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Gefitinib as First-Line Therapy Followed by Gemcitabine and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: cisplatin|DRUG: gefitinib|DRUG: gemcitabine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G-CSF in Decompensated Cirrhosis: an Open Label Trial
Status: UNKNOWN
Conditions: Cirrhosis, Liver
Interventions: DRUG: G-CSF|DRUG: Standard Medical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer
Status: COMPLETED
Conditions: Locally Advanced Lung Cancer; Metastatic Lung Cancer
Interventions: DRUG: Tislelizumab|DRUG: Paclitaxel|DRUG: Gemcitabine|DRUG: Etoposide|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities
Status: COMPLETED
Conditions: Abscess
Interventions: DRUG: Methylene Blue|DRUG: 20% I.V. Fat Emulsion|DEVICE: Insertion of optical fiber|DEVICE: Laser illumination, 5 minutes|DEVICE: Laser illumination, 10 minutes|DEVICE: Laser illumination, 15 minutes|DEVICE: Laser illumination, 20 minutes|DEVICE: Laser illumination, 25 minutes|DEVICE: Laser illumination, 30 minutes|DEVICE: Optical spectroscopy measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pramipexole in Out-patients With Idiopathic Restless Legs Syndrome (IRLS)
Status: COMPLETED
Conditions: Restless Legs Syndrome
Interventions: DRUG: Pramipexole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Upfront Related Donor Transplantation in Patients With Myelodisplatic Syndrome : a Phase 2 Trial
Status: NOT_YET_RECRUITING
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Hematopoietic stem-cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Neurodevelopmental Disorders|Cerebral Palsy
Interventions: DRUG: Methylphenidate|DRUG: Modafinil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Education Materials for Prevention of FAS in Russia
Status: COMPLETED
Conditions: Fetal Alcohol Spectrum Disorders|Fetal Alcohol Syndrome (FAS)|Alcohol Related Neurodevelopmental Disorder|Alcohol Use Complicating Pregnancy, Unspecified Trimester
Interventions: BEHAVIORAL: Positive FASD education brochure|BEHAVIORAL: Negative FASD education brochure|BEHAVIORAL: Active comparator (a general women's health brochure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Mid-term Effect of Repeated Transcranial Magnetic Stimulation on Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DEVICE: repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label, Single- & Multiple-Dose Study to Investigate the Pharmacokinetics of Sitagliptin 100 mg in Healthy Chinese Adult Subjects (0431-108)(COMPLETED)
Status: COMPLETED
Conditions: Diabetes Mellitus Non-insulin-dependent
Interventions: DRUG: sitagliptin phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise Capacity Study of LCZ696 vs. Enalapril in Patients With Chronic Heart Failure and Reduced Ejection Fraction.
Status: COMPLETED
Conditions: Chronic Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: LCZ696|DRUG: Enalapril|DRUG: Placebo matching enalapril|DRUG: Placebo matching LCZ696
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessing Mental Health Providers' Clinical Knowledge and Skills Via an Online Training on LGBTQ-affirmative Cognitive-behavioral Therapy
Status: COMPLETED
Conditions: LGBTQ
Interventions: BEHAVIORAL: LGBTQ-affirmative CBT training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of the Effect of Transcranial Stimulations in Aphasic Subject Within a Year of Their Stroke
Status: COMPLETED
Conditions: Aphasia|Stroke
Interventions: DEVICE: eldith DC-stimulator, configuration F7A|DEVICE: eldith DC-stimulator, configuration F7C|DEVICE: eldith DC-stimulator, configuration T5A|DEVICE: eldith DC-stimulator, configuration T5C|DEVICE: eldith DC-stimulator, configuration Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Using of Testes' Shocker in Improving Sexual Activity
Status: COMPLETED
Conditions: Sexual Dysfunction|Sexual Abstinence|Sexual Desire Disorder|Erectile Dysfunction|Erectile Dysfunction Following Radical Prostatectomy|Erectile Dysfunction Following Cryotherapy|Erectile Dysfunction With Diabetes Mellitus|Erectile Dysfunction Following Radiation Therapy|Erectile Dysfunction Following Urethral Surgery|Erectile Dysfunction With Type 2 Diabetes Mellitus
Interventions: DEVICE: JT Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PD-1 Inhibitor Combination With Autologous Cell Immunotherapy in the Metastatic Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Cell Carcinoma|Clear Cell Renal Cell Carcinoma
Interventions: BIOLOGICAL: SHR-1210|BIOLOGICAL: CIK cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Acute Coronary Event Smoking Study
Status: COMPLETED
Conditions: Smoking Cessation|Acute Coronary Syndrome
Interventions: BEHAVIORAL: Behavioral Activation (BA)|BEHAVIORAL: Standard Smoking Cessation Counseling|DRUG: Nicotine patch|OTHER: Printed Self-help materials for Smoking Cessation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Extended Adjuvant Endocrine Therapy in Patients With Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Letrozole|DRUG: Anastrozole|DRUG: Exemestane|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lanreotide Autogel in Patients With Acromegaly Previously Treated With Octreotide LAR
Status: COMPLETED
Conditions: Acromegaly
Interventions: DRUG: Lanreotide (Autogel formulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Once-Daily Ciprodexa Otic Foam Compared to Twice-daily Ciprodex Ear Drops in Acute Otitis Externa
Status: COMPLETED
Conditions: Otitis Externa|Otorhinolaryngologic Diseases|Ear Diseases|Otitis
Interventions: DRUG: Ciprodex Otic Suspension|DRUG: Ciprodexa Otic Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: insulin glargine|DRUG: sitagliptin/metformin|BEHAVIORAL: lifestyle therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics, Metabolism and Excretion Routes of ASP3652 in Man, After Administration of 14C Radio Labeled ASP3652
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP3652
Interventions: DRUG: ASP3652
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Value of Cardiac Magnetic Resonance (CMR) Derived Parameters for Diagnosing Left Ventricular Non-compaction Cardiomyopathy
Status: COMPLETED
Conditions: Left Ventricular Non-compaction Cardiomyopathy|Left Ventricular Failure|Left Ventricular Hypertrophy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) Study
Status: COMPLETED
Conditions: Asthma|Allergic Sensitization
Interventions: BIOLOGICAL: Oral mucosal immunoprophylaxis (OMIP)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of GC1102(Recombinant Hepatitis B Immunoglobulin) in Chronic Hepatitis B Patients
Status: UNKNOWN
Conditions: Hepatitis B
Interventions: DRUG: GC1102|OTHER: GC1102 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immune Non-inferiority and Safety of a Vi-DT Typhoid Conjugate Vaccine
Status: UNKNOWN
Conditions: Typhoid
Interventions: BIOLOGICAL: Test Vaccine Vi-DT Typhoid conjugate|BIOLOGICAL: Control Vaccine Typbar TCV®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Demonstrate Non-inferior Immunogenicity of Yuxi Walvax MPV ACYW® Vaccine in Healthy Subjects Aged 2-10 Years
Status: COMPLETED
Conditions: Neisseria Meningitides Meningitis
Interventions: BIOLOGICAL: Yuxi Walvax MPV ACYW® vaccine|BIOLOGICAL: Sanofi Pasteur Menactra® vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Myofascial Release Therapy and Endurance Training on Mechanical Back Pain
Status: COMPLETED
Conditions: Back Pain, Low
Interventions: OTHER: Group A will receive myofascial release therapy + conventional physical therapy|OTHER: Group B will receive endurance training of the trunk extensor muscles + conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-label Phase 4 Study to Explore Immunogenicity of the Liquid Formulation of Saizen® in Subjects With Adult Growth Hormone Deficiency (AGHD)
Status: COMPLETED
Conditions: Adult Growth Hormone Deficiency
Interventions: DRUG: Saizen® solution for injection (referred as Saizen®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Versus Synthetic Versus Biological Sling for Trans-obturator Correction of Urinary Stress Incontinence
Status: UNKNOWN
Conditions: Stress Urinary Incontinence
Interventions: PROCEDURE: Autologous transobturator tape procedure|PROCEDURE: Synthetic transobturator tape procedure|PROCEDURE: Biological transobturator tape procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Demonstrate the Efficacy and Tolerability of Ferrous Bisglycinate Chelate in Iron Deficiency Anaemia and to Compare These With Those of Ferrous Ascorbate.
Status: COMPLETED
Conditions: Haematopoiesis
Interventions: DRUG: ferrous ascorbate|DIETARY_SUPPLEMENT: ferrous bisglycinate chelate 1 OD|DIETARY_SUPPLEMENT: ferrous bisglycinate chelate 2 OD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Two Surgical Approaches for Root Coverage of Teeth Presenting Gingival Recession and Non-carious Cervical Lesion
Status: COMPLETED
Conditions: Gingival Recession
Interventions: PROCEDURE: CAF|PROCEDURE: R|PROCEDURE: MC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Metabonomics Study on the Treatment of Heart Failure After Myocardial Infarction With Modified Wenxin Decoction
Status: UNKNOWN
Conditions: Heart Failure|Myocardial Infarction
Interventions: DRUG: Modified Wenxin Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, Multicenter, Open-label Study to Assess the Immunogenicity of an Investigational Hib Vaccine (NU300)in Toddlers
Status: UNKNOWN
Conditions: Infectious Disease
Interventions: BIOLOGICAL: NU300|BIOLOGICAL: ActHIB|BIOLOGICAL: Prevnar 13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PRF+1% MF for Class II Mandibular Furcation Defects
Status: COMPLETED
Conditions: Furcation Defects
Interventions: PROCEDURE: Open flap debridement (OFD)|PROCEDURE: OFD with Platelet rich fibrin (PRF)|PROCEDURE: OFD with Platelet rich fibrin (PRF)+1% Metformin (Drug) in gel form
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermia/Thermal Therapy With Chemotherapy to Treat Inoperable or Metastatic Tumors
Status: UNKNOWN
Conditions: Neuroendocrine Cancer|Small Cell Lung Cancer|Non-Small Cell Lung Cancer|Gastric Cancer
Interventions: OTHER: thermochemotherapy|DRUG: Cisplatin, Gemcitabine, Interferon-a|OTHER: thermochemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ECMELLA vs. ECMO on 30-day Mortality
Status: UNKNOWN
Conditions: Cardiac Arrest|Cardiopulmonary Arrest|Extracorporeal Membrane Oxygenation Complication|Cardiogenic Shock|Acute Myocardial Infarction
Interventions: DEVICE: VA-ECMO|DEVICE: ECMELLA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Anticoagulation With Left Atrial Appendage Closure After AF Ablation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: WATCHMAN FLX Implant|DRUG: Market-approved OAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir/Lamivudine|DRUG: Atazanavir|DRUG: Efavirenz|DRUG: Emtricitabine/Tenofovir disoproxil fumarate|DRUG: Ritonavir|DRUG: Abacavir/Lamivudine placebo|DRUG: Emtricitabine/Tenofovir disoproxil fumarate placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Margin Elevation Vs Crown Lengthening
Status: COMPLETED
Conditions: Endodontically Treated Teeth
Interventions: PROCEDURE: Deep Margin Elevation using resin composite|PROCEDURE: Surgical Crown Lengthening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of Gemtuzumab Ozogamicin (GO) With Daunorubicine and Cytarabine in Untreated Acute Myeloid Leukemia (AML) Aged of 50-70 Years Old
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: conventional chemotherapy (AraC + Daunorubicin),|DRUG: Mylotarg associated with conventional chemotherapy (AraC + Daunorubicin),
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety, Tolerability, and Immunogenicity of Candidate Human Cytomegalovirus Vaccine in Healthy Adults
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: DRUG: VBI-1501A 0.5 μg|DRUG: VBI-1501A 1.0 μg|DRUG: VBI-1501A 2.0 μg|DRUG: VBI-1501 1.0 μg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Structural Modification In Supraglottic Airway Device
Status: RECRUITING
Conditions: Airway Complication of Anesthesia|Ventilation Therapy; Complications|Hypoxia|Hypoventilation
Interventions: DEVICE: A/Z Supraglottic airway
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Short-term Efficacy of Furosemide, Isosorbide Dinitrate and Their Combination in ADHF
Status: WITHDRAWN
Conditions: Heart Decompensation
Interventions: DRUG: Furosemide|DRUG: Isosorbide Dinitrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT