pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Walking on Sand With Dietary Intervention in Overweight Type 2 Diabetes Mellitus Patients.
Status: COMPLETED
Conditions: Walking, Difficulty|Diabetes Mellitus, Type 2|Hemoglobin; Hb-SC
Interventions: OTHER: Walking on soft-sand|OTHER: Walking on Levelled Surface
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ONTAK and CHOP in Newly Diagnosed, Peripheral T-Cell Lymphoma
Status: COMPLETED
Conditions: Lymphoma, T-Cell, Peripheral
Interventions: DRUG: Denileukin diftitox|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Prednisone|OTHER: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: SYR-472|DRUG: SYR-472|DRUG: SYR-472|DRUG: SYR-472|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Humanized CD7 CAR T-cell Therapy for r/r CD7+ Acute Leukemia
Status: UNKNOWN
Conditions: T Lymphoblastic Leukemia/Lymphoma|Mixed Phenotype Acute Leukemia|Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Humanized CD7 CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Vomiting in Children: Comparison Tri - Versus bi -Prophylaxis
Status: COMPLETED
Conditions: Postoperative Vomiting
Interventions: DRUG: Dexamethasone + ondansetron + Placebo|DRUG: Dexamethasone + ondansetron + Droperidol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Efficacy of Cisplatin Micelle Injection (HA132) in Patients With Advanced Malignant Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignant Solid Tumors
Interventions: DRUG: Cisplatin micelle injection (HA132)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mri characterIzation of Troponin Elevation After Cardiac Surgery
Status: COMPLETED
Conditions: Cardiac Surgery|Cardiopulmonary Bypass
Interventions: PROCEDURE: MRI|BIOLOGICAL: Postoperative dosage of released troponin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: DFD-29 (Minocycline) Fasting|DRUG: DFD-29 (Minocycline) Fed|DRUG: Solodyn (Minocycline) Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Perioperative Chemotherapy Combined With Serplulimab or Placebo for pMMR Locally Advanced Gastric Adenocarcinoma (FOCUS-05)
Status: RECRUITING
Conditions: Adenocarcinoma of the Stomach|Adenocarcinoma of Esophagogastric Junction|Proficient Mismatch Repair
Interventions: DRUG: S1|DRUG: Oxaliplatin|DRUG: Serplulimab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3437943 in Participants With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: LY3437943|DRUG: Dulaglutide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study for Evaluating the Clinical Effectiveness and Safety of Respiratory Rehabilitation Software 'Redpill Breath'(COPD, Asthma, Lung Cancer, Etc.)
Status: UNKNOWN
Conditions: Respiratory System Disease|Chronic Obstructive Pulmonary Disease|Asthma Copd|Lung Cancer|Lung Diseases|Pulmonary Rehabilitation|Respiratory Rehabilitation|Home Based Rehabilitation|Mobile Application|Rehabilitation
Interventions: BEHAVIORAL: Conventional rehabilition treatment(e.g leaflet) educated by hospital|DEVICE: Digital treatment based on Respiratory Rehabilitation Software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Saffron (Crocus Sativus) on Pain Control After Root Canal Therapy in Teeth With Vital Pulps
Status: COMPLETED
Conditions: Post-treatment Pain Following Root Canal Therapy
Interventions: OTHER: starch|OTHER: saffron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Assessment Method for Driving Ability Using Driving Simulator in Healthy Volunteers #3
Status: COMPLETED
Conditions: Healthy Participants
Interventions: OTHER: Road-tracking test|OTHER: Car-following test|OTHER: Harsh-braking test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Nocturnal Parenteral Nutrition on Bone Turnover and Energy Metabolism
Status: RECRUITING
Conditions: Intestinal Failure|Osteoporosis|Insulin Sensitivity
Interventions: DIETARY_SUPPLEMENT: Parenteral nutrition|DIETARY_SUPPLEMENT: Parenteral nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Vorinostat,Lenalinomide and Dexamethasone in Multiple Myeloma Refractory to Previous Lenalinomide Containing Regimens
Status: COMPLETED
Conditions: Multiple Myeloma
Interventions: DRUG: Vorinostat, Lenalinomide and Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology
Status: COMPLETED
Conditions: Hearing Impairment, Sensorineural
Interventions: DEVICE: CP1150 Sound Processor|DEVICE: CP1150 NF|DEVICE: CP1150 + FF|DEVICE: CP1110
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Point-of-care Health Literacy and Activation Information to Improve Diabetes Care
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: BEHAVIORAL: Empowering Patients in Chronic Care (EPIC)|BEHAVIORAL: Enhanced Usual Care (EUC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase I Trial to Assess the Safety, Tolerability and Immunogenicity of a Ebola Virus Vaccine
Status: COMPLETED
Conditions: Ebola Viruses
Interventions: BIOLOGICAL: BPSC-1001 (VSVΔG-ZEBOV)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: STRONGer Together: A Small Group Intervention for Children With Asthma and Anxiety/Depression
Status: ACTIVE_NOT_RECRUITING
Conditions: Childhood Asthma|Childhood Anxiety|Childhood Depression
Interventions: BEHAVIORAL: STRONGer Together
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Statin Therapy to Improve Atherosclerosis in HIV Patients
Status: COMPLETED
Conditions: Cardiovascular Disease|HIV|Atherosclerosis|Inflammation|Statins, HMG-CoA|HIV Infections
Interventions: DRUG: atorvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Part vs Whole Task Mastery Training for Laparoscopic Hernia Repair
Status: COMPLETED
Conditions: Hernia
Interventions: BEHAVIORAL: Online Video Curriculum|BEHAVIORAL: Whole Task Mastery Training|BEHAVIORAL: Part Task Mastery Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular|Biliary Tract Cancer|Secondary Liver Cancer|Liver Metastases
Interventions: DRUG: RO7119929|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder
Status: NOT_YET_RECRUITING
Conditions: Alcohol Use Disorder
Interventions: DEVICE: Low Intensity Focused Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: EFFECT OF SCAR RELEASE TECHNIQUES ON CHRONIC SCAR PAIN AND MOBILITY POST CESAREAN SECTION
Status: UNKNOWN
Conditions: Cesarean Section Complications
Interventions: OTHER: Scar release techniques + therapeutic ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Zero Ischemia Laparoscopic Partial Nephrectomy
Status: WITHDRAWN
Conditions: Small Renal Mass
Interventions: PROCEDURE: Renal Artery Embolization|PROCEDURE: Partial Nephrectomy (Surgical Resection)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Composite Repair Using Silane Coupling Agent
Status: NOT_YET_RECRUITING
Conditions: Tooth Discoloration|Hypersensitivity|Tooth Fracture|Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Silane coupling agent|OTHER: Adhesive containing silane.(Intervention 1 )|OTHER: Acid resistance silane containing adhesive.(Intervention 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Efficiency of Pain Neuroscience Education in Patients With Chronic Pain After Breast Cancer Surgery
Status: RECRUITING
Conditions: Breast Cancer
Interventions: OTHER: Pain Neuroscience Education|OTHER: Biomedical Pain Education|OTHER: Standard Physiotherapy Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Proprioceptive Neuromuscular Facilitation in Pain Relief
Status: COMPLETED
Conditions: Migraine Disorders
Interventions: OTHER: PNF contract-relax|OTHER: Static stretching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Management and Evolution of Acute Diverticulitis With Pericolic Free Gas
Status: COMPLETED
Conditions: Diverticulitis|Diverticulitis Colon|Diverticulitis; Perforation, Bowel|Diverticulitis of Sigmoid
Interventions: DIAGNOSTIC_TEST: CT imaging
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of the Effect of the Cognitive Orientation to Daily Occupational Performance (CO-OP) on Cognitive Impairment in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Cognitive Impairment
Interventions: BEHAVIORAL: CO-OP treatment protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Assessing Efficacy and Safety of Sunitinib and Exemestane in Patients With ER [Estrogen Receptor] + and/or PgR [Progesterone Receptor] + Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: exemestane|DRUG: sunitinib malate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laparoscopic Inguinal Hernia Repair in Infancy and Childhood
Status: COMPLETED
Conditions: Congenital Inguinal Hernia
Interventions: PROCEDURE: Hernial sac ligation in continuity|PROCEDURE: Hernial sac disconnection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Analgesic Efficacy of Ultrasound Guided Adductor Canal Block Versus 4 in 1 Block in Patients Undergoing Knee Surgeries: A Comparative Randomized Double Blinded Study .
Status: COMPLETED
Conditions: Comparing the Analgesic Outcome by ( 4 in 1 Block ) & ( Adductor Canal Block )
Interventions: PROCEDURE: adductor canal block|PROCEDURE: 4 in one block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
Status: COMPLETED
Conditions: Chronic Pain|Low Back Pain
Interventions: DRUG: Tapentadol PR|OTHER: Observation period|DRUG: Tapentadol PR
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study- REVEAL 475 for Bevonescein-Assisted Nerve Visualization in Head & Neck Surgery
Status: RECRUITING
Conditions: Head and Neck Surgery
Interventions: DEVICE: REVEAL 475 System|DRUG: Bevonescein
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intervention to Improve Self-Care of Symptoms in Breast Cancer Survivors on Adjuvant Endocrine Therapy
Status: WITHDRAWN
Conditions: Breast Cancer Female
Interventions: BEHAVIORAL: Behavioral Intervention.|OTHER: Nutritional Education.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Recombinant Human Growth Hormone Therapy for Children With PMS
Status: COMPLETED
Conditions: Phelan-McDermid Syndrome|Growth Hormone Treatment
Interventions: DRUG: recombinant human growth hormone|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Antifungal Treatment for Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: 33525|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position
Status: COMPLETED
Conditions: Cardiac Index
Interventions: DEVICE: Standard abdominal pressure|DEVICE: Low abdominal pressure|DRUG: Conventional neuromuscular blockade|DRUG: Deep neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)
Status: COMPLETED
Conditions: Complicated Intra-abdominal Infection|Complicated Urinary Tract Infection
Interventions: DRUG: Imipenem+Cilastatin/Relebactam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Immune Response of V503 to Gardasil in 16- to 26-year-old Men (V503-020)
Status: COMPLETED
Conditions: Papilloma Viral Infection
Interventions: BIOLOGICAL: V503|BIOLOGICAL: GARDASIL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Corticosteroid Use in Premature Babies and Lung Ultrasonografi Use in the Progression to Bronchopulmonary Dysplasia
Status: ENROLLING_BY_INVITATION
Conditions: Bronchopulmonary Dysplasia|Premature Birth
Interventions: DEVICE: Lung Ultrasonografi
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder|Depression
Interventions: DRUG: Venlafaxine|DRUG: Sertraline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Of Neoadjuvant Chemotherapy (NAC)In Upper Tract Urothelial Carcinoma (UTUC)
Status: TERMINATED
Conditions: Urothelial Cancer|Bladder Cancer
Interventions: DRUG: Neoadjuvant Cisplatin and Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diacutaneous Fibrolysis on Carpal Tunnel Syndrome
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: OTHER: Actual Diacutaneous Fibrolysis|OTHER: Sham Diacutaneous Fibrolysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Oxygenation Values in Healthy Adults Volunteers Measured With RheoPatch and NIRO-200NX
Status: COMPLETED
Conditions: Healthy|Adults
Interventions: DEVICE: Cerebral oximetry using Rheopatch|DEVICE: Cerebral oximetry using NIRO-200NX
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Lumbar Traction on the Straight Leg Raise Test and Pain
Status: COMPLETED
Conditions: Prolapsed Intervertebral Disc
Interventions: PROCEDURE: Mechanical Traction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KRAS Wild-type Metastatic Colorectal Cancer Trial
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: Dacogen™ (decitabine)|DRUG: Vectibix® (panitumumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Acute Leukemia|Myelodysplastic Syndromes|Chronic Myeloid Leukemia|Chronic Lymphocytic Leukemia|Myeloproliferative Neoplasm|Lymphoma|Chronic Myelomonocytic Leukemia|Pro-Lymphocytic Leukemia|Myelofibrosis
Interventions: DRUG: Busulfan|DRUG: Fludarabine|PROCEDURE: PBSC Hematopoietic Stem Cell Transplantation (HSCT)|DRUG: Post-Transplant Cyclophosphamide|DRUG: Mesna|DRUG: Tacrolimus|DRUG: Mycophenolate Mofetil|OTHER: Patient Reported Outcomes|DRUG: Melphalan|RADIATION: Total-body irradiation|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PharmacofMRI (Functional Magnetic Resonance Imaging) of Anxiolytic Medications (Alprazolam)
Status: COMPLETED
Conditions: Anxiety Disorders
Interventions: DRUG: 0.25 mg alprazolam|DRUG: 1.0 mg alprazolam|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Metabolic Profile of Users of Hormonal and Non-hormonal Contraceptives
Status: COMPLETED
Conditions: Contraceptive Usage|Metabolic Syndrome|Body Weight Changes
Interventions: DEVICE: Intrauterine device|DRUG: Combined Oral Contraceptive|DRUG: Progestin-only pills|DRUG: Depot-Medroxyprogestereone Acetate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Finding the Right Tenofovir/Emtricitabine Regimen for Pre-Exposure Prophylaxis (PrEP) in Transgender Women
Status: COMPLETED
Conditions: HIV Prevention
Interventions: DRUG: Tenofovir Disoproxil Fumarate/Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Low-dose Radiotherapy on Tumor Immune Microenvironment in Oligometastases of NSCLC After Immunotherapy
Status: WITHDRAWN
Conditions: Low-dose Radiotherapy|Tumor Microenvironment|Non-Small Cell Lung Cancer
Interventions: RADIATION: low dose radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Identification of Genes That Predict Local Recurrence in Samples From Patients With Breast Cancer Treated on NSABP-B-28
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: GENETIC: RNA analysis|GENETIC: gene expression analysis|GENETIC: microarray analysis|GENETIC: reverse transcriptase-polymerase chain reaction|OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors
Status: UNKNOWN
Conditions: Glioma|Metastatic Brain Cancer
Interventions: DEVICE: ExAblate Transcranial System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intermittent Heat and Cold Therapy on Comfort During Labor
Status: NOT_YET_RECRUITING
Conditions: Labour Pain|Cold Therapy|Heat Therapy
Interventions: PROCEDURE: Intermittent heat and cold versus heat-only therapy|PROCEDURE: Heat- only Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer (NSCLC)|Colorectal Cancer (CRC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Advanced Solid Tumors
Interventions: DRUG: RMC-6236
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrointestinal Tolerability Following Multiple Servings of a Novel Dietary Fiber
Status: COMPLETED
Conditions: Signs and Symptoms, Digestive
Interventions: OTHER: Negative Control|OTHER: Positive Fiber Control|OTHER: Novel Fiber|OTHER: Novel Fiber|OTHER: Novel Fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Efficacy and Safety Study of GB-0998 for Treatment of Steroid-resistant Polymyositis and Dermatomyositis (PM/DM)
Status: COMPLETED
Conditions: Polymyositis|Dermatomyositis
Interventions: DRUG: GB-0998|DRUG: Placebo of GB-0998
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment
Status: UNKNOWN
Conditions: Allergic Rhinitis
Interventions: DRUG: Desloratadine + Prednisolone|DRUG: Dexchlorpheniramine + Betamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Low and High Ligation With Apical Lymph Node Dissection in the Laparoscopy Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: PROCEDURE: Low ligation|PROCEDURE: High ligation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Targeting Network Dysfunction in Apathy of Late-life Depression Using Digital Therapeutics
Status: NOT_YET_RECRUITING
Conditions: Major Depressive Disorder|Apathy
Interventions: BEHAVIORAL: Targeted Cognitive Training Intervention|BEHAVIORAL: General Cognitive Training Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Late Reperfusion With Percutaneous Coronary Intervention in Patients With ST-segment Elevation Myocardial Infarction
Status: RECRUITING
Conditions: Ischemic Heart Disease|ST-segment Elevation Myocardial Infarction
Interventions: PROCEDURE: PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
Status: RECRUITING
Conditions: Advanced Esophageal Squamous Cell Carcinoma|Advanced Renal Cell Carcinoma|Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC V8|Clinical Stage IIB Cutaneous Melanoma AJCC V8|Clinical Stage IIC Cutaneous Melanoma AJCC V8|Clinical Stage III Cutaneous Melanoma AJCC V8|Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC V8|Clinical Stage IV Cutaneous Melanoma AJCC V8|Clinical Stage IV Esophageal Squamous Cell Carcinoma AJCC V8|Esophageal Carcinoma|Gastroesophageal Junction Adenocarcinoma|Hepatocellular Carcinoma|Locally Advanced Urothelial Carcinoma|Lung Non-Small Cell Carcinoma|Malignant Solid Neoplasm|Metastatic Colorectal Carcinoma|Metastatic Cutaneous Melanoma|Metastatic Esophageal Squamous Cell Carcinoma|Metastatic Head and Neck Squamous Cell Carcinoma|Metastatic Urothelial Carcinoma|Recurrent Esophageal Squamous Cell Carcinoma|Recurrent Head and Neck Squamous Cell Carcinoma|Renal Cell Carcinoma|Stage III Renal Cell Cancer AJCC V8|Stage IV Colorectal Cancer AJCC V8|Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC V8|Stage IV Renal Cell Cancer AJCC V8|Unresectable Cutaneous Melanoma|Unresectable Esophageal Squamous Cell Carcinoma|Urothelial Carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ultrasound of Diaphragmatic Musculature in Mechanically Ventilated Patients.
Status: COMPLETED
Conditions: Mechanical Ventilation
Interventions: OTHER: Pressure controlled mandatory ventilation mode (P-CMV)|OTHER: Pressure synchronized intermittent mandatory ventilation|OTHER: Pressure support mode (PS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: To Determine the Gait and Functional Improvement in Total Knee Arthroplasty
Status: WITHDRAWN
Conditions: Degenerative Arthritis
Interventions: DEVICE: Orthosensor™ VERASENSE™ Knee System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combined Use of Contact Aspiration and the Stent Retriever Technique Versus Stent Retriever Alone for Recanalisation in Acute Cerebral Infarction
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: COMBINATION_PRODUCT: Combined contact aspiration/Stent Retriever Technique|DEVICE: Stent retriever technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Efficacy of Subcutaneous Ivermectin With or Without Zinc in COVID-19 Patients
Status: UNKNOWN
Conditions: Coronavirus Infection|COVID|Sars-CoV2
Interventions: DRUG: Ivermectin Injectable Solution|OTHER: Injectable Placebo|DRUG: Zinc|DRUG: Placebo empty capsule|DRUG: Oral Ivermectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Single Incision Laparoscopic Varicocelectomy
Status: COMPLETED
Conditions: Varicocele
Interventions: PROCEDURE: single incision laparoscopic varicocelectomy|PROCEDURE: conventional transperitoneal laparoscopic varicocelectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers
Status: COMPLETED
Conditions: Electronic Cigarette Use
Interventions: OTHER: RELX ENDS Tobacco Flavor|OTHER: RELX ENDS Menthol Flavor|OTHER: Usual Brand Cigarette|OTHER: Nicorette White Ice Mint nicotine polacrilex gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of Rheosorbilact® Solution for Infusion, in a Complex Therapy of Sepsis.
Status: COMPLETED
Conditions: Sepsis|Intoxication; Septic
Interventions: DRUG: Rheosorbilact®|DRUG: Ringer lactate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Antibiotic Administration for Bladder OnabotulinumtoxinA Injection
Status: COMPLETED
Conditions: Overactive Bladder|Overactive Bladder Syndrome|Urge Incontinence|Urinary Incontinence, Urge
Interventions: DRUG: Single-Dose Antibiotic|DRUG: Multi-Dose Antibiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Safety and Efficacy Study of Estradiol Vaginal Capsule in Postmenopausal Women With Vulvovaginal Atrophy
Status: COMPLETED
Conditions: Vulvovaginal Atrophy|Menopause|Dyspareunia
Interventions: DRUG: Estradiol Vaginal Capsule (EVC)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Vitamin D Supplementation in Muscle Strength and Balance Training
Status: COMPLETED
Conditions: Osteoporosis, Osteopenia|Osteoporosis, Postmenopausal
Interventions: DIETARY_SUPPLEMENT: Physical exercise + Vitamin D3|OTHER: Physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Patients Who Received Inotuzumab Ozogamicin for B-cell ALL (Acute Lymphoblastic Leukemia) That Occurred Again After the Last Treatment
Status: COMPLETED
Conditions: Adult Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia
Interventions: DRUG: Inotuzumab Ozogamicin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Assessment of Cystic Fibrosis Lung Involvement With UTE Pulse Sequences
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DEVICE: MR measurements of lung morphological changes in cystic fibrosis (Avanto dot, Siemens)|DEVICE: CT measurements of lung morphological changes in cystic fibrosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of G-CSF Supplemented IVF Medium in Patients Undergoing IVF
Status: UNKNOWN
Conditions: Infertility|Embryo Development|IVF
Interventions: OTHER: G-CSF medium|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity
Status: UNKNOWN
Conditions: Valvular Heart Disease
Interventions: DRUG: increment of desflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD
Status: ACTIVE_NOT_RECRUITING
Conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Acute Biphenotypic Leukemia|Acute Leukemia of Ambiguous Lineage|Acute Undifferentiated Leukemia|Allogeneic Hematopoietic Stem Cell Transplant Recipient|Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Blastic Plasmacytoid Dendritic Cell Neoplasm|Childhood Acute Lymphoblastic Leukemia in Remission|Childhood Acute Myeloid Leukemia in Remission|Donor|Lymphoblastic Lymphoma|Myelodysplastic Syndrome With Excess Blasts|Myelodysplastic Syndrome With Excess Blasts-1|Myelodysplastic Syndrome With Excess Blasts-2|Recurrent Acute Lymphoblastic Leukemia|Recurrent Acute Myeloid Leukemia|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive|Refractory Acute Lymphoblastic Leukemia|Refractory Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia in Remission|Acute Myeloid Leukemia in Remission
Interventions: PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation|DRUG: Cyclophosphamide|DRUG: Fludarabine Phosphate|OTHER: Laboratory Biomarker Analysis|DRUG: Methotrexate|DRUG: Mycophenolate Mofetil|PROCEDURE: Peripheral Blood Stem Cell Transplantation|PROCEDURE: Peripheral Blood Stem Cell Transplantation|DRUG: Tacrolimus|DRUG: Thiotepa|RADIATION: Total-Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length
Status: COMPLETED
Conditions: Preterm Birth
Interventions: DRUG: Micronised vaginal progesterone|DEVICE: Vaginal pessary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Community Pharmacy Medication Therapy Management for Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: BEHAVIORAL: Pharmacist Heart failure MTM training|BEHAVIORAL: Patient Heart failure MTM intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ranolazine Monotherapy in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Ranolazine|DRUG: Placebo|BEHAVIORAL: Diet|BEHAVIORAL: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cluster Randomised Trial of Improved Sanitation in Rural Orissa, India
Status: COMPLETED
Conditions: Diarrhoea|Soil-transmitted Helminth Infection|Nutritional Status
Interventions: BEHAVIORAL: Provision of household latrines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Hyperoxia and Hypoxia on Fluorescence Lifetime Imaging Ophthalmoscopy in Healthy Subjects- a Randomized, Double Blind, Crossover Study
Status: UNKNOWN
Conditions: To Investigate the Effect of 100% Oxygen Breathing on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Healthy Subjects
Interventions: DRUG: SAUERSTOFF|DRUG: STICKSTOFF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Parenting Intervention for Improving Child Mental Health
Status: COMPLETED
Conditions: Behavior Problem|Conduct Disorders in Children|Mental Health Wellness 1
Interventions: BEHAVIORAL: Samarthan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Umbilical Cord Serum Versus Conventional Eyedrops
Status: UNKNOWN
Conditions: Dry Eye Syndromes
Interventions: DRUG: Optive, Ophthalmic Solution|BIOLOGICAL: Umbilical Cord Serum eye drops|DRUG: Genteal lubricant gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Vitamin B12 Supplementation to Improve B12 Status and Child Development
Status: COMPLETED
Conditions: Early Pregnancy
Interventions: DIETARY_SUPPLEMENT: Vitamin B12 fortified UHT milk|DIETARY_SUPPLEMENT: Plain UHT milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Evaluation of Periodontal Ligament Distraction Using a Modified Surgical Technique for Retraction of Maxillary Canines
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: PROCEDURE: Periodontal ligament distraction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of PD1 Blockade by Pembrolizumab With Stereotactic Body Radiotherapy in Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Solid Tumor
Interventions: RADIATION: Stereotactic body radiotherapy (SBRT)|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Single Dose Tranexamic Acid in Reducing Blood Loss During Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Colorectal Surgery
Interventions: DRUG: Tranexamic Acid Injection|DRUG: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abuse Liability of Suboxone Versus Subutex
Status: COMPLETED
Conditions: Opioid-related Disorders
Interventions: DRUG: Heroin|DRUG: Naloxone|DRUG: Low Bup Dose|DRUG: High Bup Dose|DRUG: Low Bup/Nal Dose|DRUG: High Bup/Nal Dose|DRUG: Placebo (PCB)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparing Erector Spinae Plane (ESP) and Thoracic Paravertebral (TPV) Block Analgesic Effect After Elective VATS
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgery|Thoracic
Interventions: PROCEDURE: ESP block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Core Stability Exercises
Status: TERMINATED
Conditions: Brain Injury, Vascular|Sequelae|Stroke Syndrome|Movement; Disorder, Treatment-Induced|Physical Activity
Interventions: OTHER: Core stability exercises (CSE)|OTHER: Conventional Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: ETAP|PROCEDURE: Standard Transabdominal Laparoscopic Proctectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of High Tone Therapy and TENS Therapy
Status: COMPLETED
Conditions: Peripheral Nervous System Problem
Interventions: DEVICE: high tone external muscle stimulation|DEVICE: transcutaneous electrical nerve stimulation (TENS) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study of Intraperitoneal NanoPac® in Patients With Ovarian Cancer
Status: TERMINATED
Conditions: Ovarian Carcinoma
Interventions: DRUG: NanoPac® 100 mg/m2|DRUG: NanoPac® 200 mg/m2|DRUG: NanoPac® 300 mg/m2|DRUG: NanoPac® 400 mg/m2|DRUG: Standard of Care Intravenous Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Efficacy and Safety of Multifocal Soft Contact Lens in Myopia Control
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Conservation in Adult Cardiac Surgery, What is the Way Forward in Today's Practice?
Status: UNKNOWN
Conditions: Adult Cardiac Surgery|Blood Transfusion
Interventions: DEVICE: Cell Salvage|PROCEDURE: Retrograde Autologous Prime
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Virtual Reality in the Management of Pain in Pediatrics: a Multi-center Randomized Clinical Trial (RealPED)
Status: COMPLETED
Conditions: Virtual Reality|Pediatric ALL|Pain, Procedural
Interventions: BEHAVIORAL: Virtual reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Use of Xyrem to Improve Sleep in Chronic Fatigue Syndrome
Status: TERMINATED
Conditions: Chronic Fatigue Syndrome
Interventions: DRUG: Placebo|DRUG: Sodium Oxybate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT
Status: NOT_YET_RECRUITING
Conditions: Allogeneic Stem Cell Transplant Candidate|Acute Myeloid/Lymphoblastic Leukemia|Myelodysplastic Syndrome|Myeloproliferative Neoplasm|Lymphoproliferative Disorders
Interventions: BIOLOGICAL: Cellular therapy product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Mill's Manipulation Along With Muscle Energy Technique in Lateral Epicondylitis
Status: COMPLETED
Conditions: Lateral Epicondylitis
Interventions: OTHER: Mill's Manipulation|OTHER: Mill's Manipulation and Muscle Energy Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy in Patients Undergoing Allo-HSCT With cGVHD
Status: NOT_YET_RECRUITING
Conditions: Graft-versus-host-disease|Graft Versus Host Disease, Chronic|Stem Cell Transplant Complications|Hematological Malignancy|Hematologic Cancer
Interventions: OTHER: Physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Two Methotrexate in Sync With the First Adalimumab to Prevent the Immunisation Anti Ada in Spondyloarthritis
Status: COMPLETED
Conditions: Spondyloarthritis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bedside Testing of CYP2C19 Gene for Treatment of Patients With PCI With Antiplatelet Therapy
Status: UNKNOWN
Conditions: Coronary Artery Disease|Myocardial Infarction|Heart Disease|Vascular Disease|Angina Pectoris|Cardiovascular Disease|Ischemia|Infarction|Embolism|Thrombosis|Chest Pain
Interventions: DRUG: clopidogrel|DRUG: Ticagrelor or prasugrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for the Prevention of Postdates Pregnancy
Status: COMPLETED
Conditions: Pregnancy
Interventions: PROCEDURE: Acupuncture|PROCEDURE: Sham comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bomedemstat (IMG-7289/MK-3543) in Participants With Myelofibrosis (IMG-7289-CTP-102/MK-3543-002)
Status: COMPLETED
Conditions: Myelofibrosis|Post-polycythemia Vera Myelofibrosis (PPV-MF)|Post-essential Thrombocythemia Myelofibrosis (PET-MF)|Primary Myelofibrosis (PMF)
Interventions: DRUG: Bomedemstat
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Severe Alcoholic Hepatitis With Corticoids Plus N Acetyl Cysteine Versus Corticoids Alone
Status: COMPLETED
Conditions: Alcoholic Hepatitis
Interventions: DRUG: Corticoids plus N Acetyl Cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Determining the Effectiveness of a New Phototherapy Treatment for the Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DEVICE: High Intensity Physio Light Therapy (HIPL Therapy™)|BEHAVIORAL: Education|BEHAVIORAL: Aerobic Exercise|BEHAVIORAL: Resistance Exercise|DEVICE: Placebo Physio Light Therapy (HIPL Therapy™)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT