pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Circulating miRNAs as Biomarkers of Hormone Sensitivity in Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen, Letrozole , Anastrozole, Exemestane
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Semi-rigid Ureteroscopy Versus Flexible Ureteroscopy For the Treatment of Proximal Ureteric Stone
Status: UNKNOWN
Conditions: Ureteric Stone|Stone Ureter
Interventions: PROCEDURE: Flexible Ureteroscopy|PROCEDURE: Semi-rigid Ureteroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Factors Associated With Sub - Targeted Therapeutic Dose Of Renin - Angiotensin Blockage Among Chronic Heart Failure With Reduced Ejection Fraction Patients
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Renin-Angiotensin System Inhibitor
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Preoperative Use of Darifenacin (Enablex) to Alleviate Postoperative Ureteral Stent Pain
Status: TERMINATED
Conditions: Overactive Bladder|Renal Colic|Pain, Postoperative
Interventions: DRUG: Darifenacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase III Study of Gemcitabine Compared With UFT in Patients With Completely Resected Pathological Stage IB-IIIa Non Small Cell Lung Cancer
Status: UNKNOWN
Conditions: Lung Cancer
Interventions: DRUG: gemicitabine 1000mg/m2, day1 and day 8, every 3 week, 6|DRUG: UFT 250mg/m2, daily for 1 year
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Transforaminal Epidural Injections in Lumbar Disc Herniation or Radiculitis
Status: COMPLETED
Conditions: Low Back Pain
Interventions: PROCEDURE: lumbar transforaminal epidural injections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CCCG Relapsed Acute Lymphoblastic Leukemia 2017 Study in Children
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia, in Relapse
Interventions: DRUG: Bortezomib Injection|DRUG: rituximab injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Bioequivalence of Aterixen 100 mg Tablets and Aterixen 100 mg Film-coated Tablets in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Viral Infection COVID-19
Interventions: DRUG: Aterixen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Wearable Biosensor to Track and Quantify Limb Dysfunction in Multiple Sclerosis Patients
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Myo Armband (MYO,Thalamic Labs Inc, Kitchener, ON, Canada)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: SWOG-9320 Combination Chemotherapy, Radiation Therapy, and Antiviral Therapy in Treating Patients With AIDS-Related Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|BIOLOGICAL: filgrastim|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisone|DRUG: trimethoprim-sulfamethoxazole|DRUG: vincristine sulfate|RADIATION: radiation therapy|DRUG: Intrathecal cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)
Status: COMPLETED
Conditions: Atherosclerosis|Percutaneous Coronary Intervention|Acute Coronary Syndrome
Interventions: DRUG: cangrelor P2Y12 (platelet) inhibitor|DRUG: Clopidogrel - 300 or 600 mg (study arm)|DRUG: Clopidogrel 600 mg post cangrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: asparaginase|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: etoposide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: methylprednisolone|DRUG: therapeutic hydrocortisone|DRUG: thiotepa|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of ABN401 in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer Harboring c-MET Dysregulation
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ABN401- Escalation Phase|DRUG: ABN401- Expansion Phase
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultra-Mini Versus Standard Percutaneous Nephrolithotomy For Management Of Renal Calculi. A Randomized Controlled Trial.
Status: UNKNOWN
Conditions: Stone, Kidney
Interventions: PROCEDURE: percutaneous nephrolithotomy|PROCEDURE: ultra-mini percutaneous nephrolithotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Modulation of Inflammation by Medium Cut Off Membranes
Status: UNKNOWN
Conditions: Cardiovascular Diseases|End Stage Renal Disease
Interventions: DEVICE: Medium cut off dialysis|DEVICE: Standard High Flux Dialyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Opioid-Free Pain Treatment in Trauma Patients
Status: NOT_YET_RECRUITING
Conditions: Femoral Neck Fractures|Intertrochanteric Fractures|Femoral Shaft Fracture|Distal Femur Fracture|Patella Fracture|Tibial Shaft Fracture With or Without Associated Fibula Fracture|Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)|Tibial Pilon Fracture|Talar Head, Neck, Body, or Process Fractures|Calcaneus Fractures|Lisfranc Injuries|Isolated or Multiple Metatarsal Fractures|Phalanx Fractures of the Foot, Single or Multiple|Clavicle Fractures|Proximal Humerus Fractures|Humeral Shaft Fractures|Distal Humerus Fractures (Intra or Extra-articular)|Olecranon Fractures|Radial Head or Neck Fractures|Elbow Fractures Involving a Combination of Fractures of the Radius and Uln|Forearm Fractures (Both Bone Forearm Fractures, Isolated Ulnar Shaft, Isolated Radial Shaft)|Distal Radius Fractures
Interventions: OTHER: Opioid-free pain treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Effectiveness of Standard and Innovative Products That Represent a Substitute Meal for Weight Management in a Reduction Diet
Status: RECRUITING
Conditions: Overweight and Obesity|Body Weight
Interventions: DIETARY_SUPPLEMENT: meal replacement product- STANDARD PRODUCT|DIETARY_SUPPLEMENT: Meal replacement product- INNOVATIVE PRODUCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail
Status: COMPLETED
Conditions: Onychomycosis
Interventions: DRUG: NB-002|DRUG: Vehicle control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Potential Role of Gum Arabic as Immunomodulatory Agent Among COVID 19 Patients
Status: UNKNOWN
Conditions: COVID 19
Interventions: DIETARY_SUPPLEMENT: Acacia Senegal|DIETARY_SUPPLEMENT: Pectin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC
Status: RECRUITING
Conditions: Inflammatory Bowel Diseases|Colitis, Ulcerative
Interventions: DRUG: MORF-057|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Comparison of Two Capecitabine Tablets in Patients With Colorectal or Breast Cancer
Status: COMPLETED
Conditions: Patient Participation
Interventions: DRUG: 150 mg of Xeloda®|DRUG: 150 mg of capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft Surgery
Status: COMPLETED
Conditions: Coronary Artery Bypass|Antiplatelet Agents
Interventions: DRUG: Aspirin|DRUG: Ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcome of Palliative Surgery After Translational Therapy for Metastatic Gastric Cancer Versus Maintenance Chemotherapy for Metastatic Gastric Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Gastric Cancer|Surgery|Chemotherapy
Interventions: COMBINATION_PRODUCT: Palliative surgery after translational therapy|DRUG: Chemotheraoy along
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Snack Foods and Their Impact on Mental Health and the Gut-brain Axis
Status: NOT_YET_RECRUITING
Conditions: Depression|Anxiety
Interventions: DIETARY_SUPPLEMENT: Intervention snack|DIETARY_SUPPLEMENT: Control Snack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Trial of Afatinib and Trastuzumab in HER2 Overexpressing Cancer.
Status: COMPLETED
Conditions: Breast Neoplasms|Stomach Neoplasms
Interventions: DRUG: Herceptin|DRUG: afatinib|DRUG: trastuzumab|DRUG: Herceptin|DRUG: afatinib|DRUG: afatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Mild to Moderate Persistent Asthma
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Placebo|DRUG: 400 µg per day Beclomethasone|DRUG: 200 µg per day Beclomethasone|DRUG: 100 µg per day Beclomethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of Pulse Waves, Channel Entries, and Food Attributes in Healthy Subjects With Different Constitutions
Status: UNKNOWN
Conditions: Healthy Subjects With Different Constitutions
Interventions: DIETARY_SUPPLEMENT: Coconut water|DIETARY_SUPPLEMENT: ginger tea
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cyclic Deep Brain Stimulation in Essential Tremor
Status: UNKNOWN
Conditions: Essential Tremor
Interventions: DEVICE: Abbott St Jude Medical Infinity 7 neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics of OPC-67683 in Patients With Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: DRUG: OPC-67683|DRUG: Rifafour e-275
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Six-month Study to Compare Outcome Differences and Visceral Response ... Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: BEHAVIORAL: IBS Stress Management|BEHAVIORAL: IBS Symptom Management|BEHAVIORAL: IBS Educational Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Walking for Health: an Intervention to Increase Physical Activity and Reduce Sedentary Behaviour in People With SMI
Status: COMPLETED
Conditions: Mental Illness|Schizophrenia|Bipolar Disorder|Major Depression|Psychosis
Interventions: BEHAVIORAL: Group walk and one to one coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type
Status: RECRUITING
Conditions: Stomach Cancer|Undifferentiated Type|Expanded Indication of Endoscopic Resection
Interventions: PROCEDURE: Endoscopic submucosal dissection|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Conjugated Estrogen Cream for Atrophic Vaginitis
Status: COMPLETED
Conditions: Atrophic Vaginitis|Atrophy|Vaginitis
Interventions: DRUG: PVC (daily for 21 days, 7 days off)|DRUG: PVC (twice weekly)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Pharmacological Study of Rabeprazole Sodium in Japanese Healthy Adult Male Volunteers (Study E3810)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rabeprazole sodium, 5 mg Tablets|DRUG: Rabeprazole sodium, 10 mg Tablets|DRUG: Rabeprazole sodium, 20 mg Tablets|DRUG: Rabeprazole sodium, 40 mg Tablets (two 20 mg Tablets)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perceptual Assessment of the Tracheoesophageal Voice
Status: COMPLETED
Conditions: Tracheo-Esophageal Fistula Following Tracheostomy
Interventions: OTHER: perceptual assessment of the recorded voice sample|OTHER: voice recording
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal Impairment
Status: COMPLETED
Conditions: Purpura, Thrombocytopaenic, Idiopathic
Interventions: DRUG: eltrombopag
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Iron Supplementation and Malaria Chemoprophylaxis for Prevention of Severe Anemia and Malaria in Tanzanian Infants
Status: TERMINATED
Conditions: Malaria|Anemia
Interventions: DRUG: Deltaprim (3.125 mg pyrimethamine plus 25 mg dapsone)|DRUG: iron (2 mg/kg/daily)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: CSC OnDemand: An Innovative Online Learning Platform for Implementing Coordinated Specialty Care
Status: COMPLETED
Conditions: Psychosis
Interventions: OTHER: CSC OnDemand Training Intervention|OTHER: InPerson Intervention|OTHER: Virtual InPerson Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Neovis® Total Multi Versus Systane® Balance on Ocular Dryness Associated With Meibomian Gland Dysfunction
Status: UNKNOWN
Conditions: Dry Eye|Meibomian Gland Dysfunction
Interventions: DEVICE: Neovis Total Multi|DEVICE: Systane Balance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Aerobic Exercise on Improving Sleep in Systemic Lupus Erythematosus.
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus|Sleep Disorders
Interventions: PROCEDURE: Aerobic Exercise|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: rhTSH, Radioiodine Uptake and Goiter Reduction Following 131I Therapy in Patients With Benign Nontoxic Nodular Goiter
Status: COMPLETED
Conditions: Nodular Goiter
Interventions: DRUG: Recombinant human thyrotropin (Thyrogen)|DRUG: recombinant human TSH|OTHER: isotonic saline = placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnetic Marker Localization for Occult Breast Cancer and Target Axillary Dissection in Node-positive Breast Cancer Post-neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Breast Neoplasm|Chemotherapy Effect
Interventions: DEVICE: Magnetic seed localization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIME Study: Therapeutic Hypothermia for Infants With Mild Encephalopathy
Status: NOT_YET_RECRUITING
Conditions: Hypoxic-Ischemic Encephalopathy Mild|Neonatal Encephalopathy
Interventions: OTHER: Therapeutic Hypothermia|OTHER: Normothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients
Status: UNKNOWN
Conditions: AML in Remission
Interventions: DRUG: Idarubicin|DRUG: ID cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olanzapine Versus Aripiprazole in the Treatment of Acutely Ill Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Olanzapine|DRUG: Aripiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Peripheral Blood Autologous CD34+ Cell Transplantation Promotes Angiogenesis With Atherosclerotic Ischemia for Elderly
Status: UNKNOWN
Conditions: Atherosclerotic Ischemic Disease
Interventions: PROCEDURE: the cell transplantation group|DRUG: the control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study to Evaluate Effect, Safety and Tolerability of Betaferon Standard Dose of 250µg in Patients of Chinese Origin With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: Interferon beta-1b (Betaseron, BAY86-5046)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pandemic Triage Score in Patients With Known or Suspected Severe Acute Respiratory Syndrome (SARS) CoronaVirus (CoV) 2 Infection
Status: COMPLETED
Conditions: SARS-CoV-2 Acute Respiratory Disease|Covid19
Interventions: DIAGNOSTIC_TEST: STC-19 score
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: E. Coli for Prevention of Catheter UTI in SCI Patients
Status: COMPLETED
Conditions: Urinary Tract Infection(UTI)
Interventions: DEVICE: Insertion of a urinary catheter coated with benign E. coli
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: PREVENTION
Clinical trial: Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
Status: RECRUITING
Conditions: Advanced Cancer|Advanced Malignancies|Bladder Cancer|Cervical Cancer|Esophageal Cancer|Gastric Cancer|Gastroesophageal-junction Cancer (GEJ)|Head and Neck Squamous Cell Carcinoma (HNSCC)|Non-Small Cell Lung Cancer (NSCLC)|Ovarian Cancer|Renal Cell Carcinoma (RCC)|Triple Negative Breast Cancer (TNBC)
Interventions: DRUG: AB598|DRUG: Zimberelimab|DRUG: Carboplatin|DRUG: Pemetrexed|DRUG: Fluorouracil|DRUG: Leucovorin|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Two Different Formulations of 6-mercaptopurine. Tablet Versus Oral Liquid
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia|6-mercaptopurine Therapy
Interventions: DRUG: Xaluprine|DRUG: Puri-Nethol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab and Concurrent Radiation in Patients With Previously Treated Carcinoma of Unknown Primary
Status: TERMINATED
Conditions: Carcinoma, Unspecified Site
Interventions: DRUG: Pembrolizumab|RADIATION: External Beam Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy of Salmon Protein Hydrolysate Powder on Energy Increase and Anti-inflammatory Modulation in Healthy Males and Females
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Salmon Protein Hydrolysate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Trial Comparing Patching With Active Vision Therapy to Patching With Control Vision Therapy as Treatment for Amblyopia
Status: TERMINATED
Conditions: Amblyopia
Interventions: DEVICE: Patching|PROCEDURE: Near activities|PROCEDURE: Active vision therapy|PROCEDURE: Control vision therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Muscle Activity in Exercise Bike and Elliptical Trainer in Individuals With Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DIAGNOSTIC_TEST: muscle activation of the vastus lateralis, vastus medialis, gluteus medius, tibialis anterior, rectus abdominis and paravertebral muscles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Saccharomyces Boulardii in Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Diarrhea Dominant Irritable Bowel Syndrome
Interventions: DRUG: Saccharomyces boulardii|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inactivated Influenza A/H9N2 Vaccine With and Without MF59 Adjuvant in Ambulatory Adults
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Influenza A/H9N2 vaccine|DRUG: MF59 adjuvant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Microsurgical Instruments and Magnification May Enhance Treatment Outcomes Of Laterally Moved, Coronally Advanced Flap in Miller Class III Isolated Recession Defects
Status: COMPLETED
Conditions: Gingival Recession, Mucogingival Surgery
Interventions: PROCEDURE: laterally moved coronally advanced flap with microsurgical instruments and x2.5 loupe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of SU011248 Versus Chemotherapy For Patients With Previously Treated Triple Receptor Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: SU011248|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Surface Ablation With Corneal Cross Linking in Mild Keratoconus
Status: UNKNOWN
Conditions: Keratoconus|Corneal Cross-Linking
Interventions: PROCEDURE: Photorefractive Keratectomy with Corneal Cross-Linking
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Low-dose PegIntron on ALT Normalization in Japanese Patients With Chronic Hepatitis C (Study P04508)(COMPLETED)
Status: COMPLETED
Conditions: Hepatitis C, Chronic|Hepatitis C
Interventions: BIOLOGICAL: PegIntron (peginterferon alfa-2b)|BIOLOGICAL: PegIntron (peginterferon alfa-2b)|BIOLOGICAL: PegIntron (peginterferon alfa-2b)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics (PK)/Pharmacodynamics (PD) of MOR106 in Subjects With Moderate to Severe Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: MOR 106|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth
Status: RECRUITING
Conditions: Small Intestinal Bacterial Overgrowth
Interventions: BIOLOGICAL: Fecal Microbiota Transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Combination of Two Approved Chemotherapy Drugs and Radiation Prior to Surgery in Localized Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreas Adenocarcinoma|Resectable Pancreatic Cancer
Interventions: DRUG: Gemcitabine 1000 mg|DRUG: nab-paclitaxel|RADIATION: Stereotactic Body Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Mechanism Study of MLN1202 on Atherosclerotic Inflammation in Participants With Stable Atherosclerotic Cardiovascular Disease
Status: WITHDRAWN
Conditions: Atherosclerotic Cardiovascular Disease
Interventions: DRUG: MLN1202|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Education With Mobile App on Metabolic Control in Patients With Type 2 Diabetes
Status: RECRUITING
Conditions: Female
Interventions: BEHAVIORAL: Educational intervention with App and web site education|BEHAVIORAL: Educational interventión with web site education|OTHER: Control group with nutritional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Adebrelimab Plus Chemotherapy as Neoadjuvant Therapy in Resectable NSCLC Harboring Driver Gene Mutations
Status: NOT_YET_RECRUITING
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Adebrelimab|DRUG: paclitaxel for injection (albumin bound)|DRUG: Cisplatin or Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abemaciclib for the Treatment of Luminal Metastatic breAst caNcer in the Real-life Clinical pracTice in Russia.
Status: COMPLETED
Conditions: HR+/HER2- Breast Cancer|Metastatic Disease|Аdvanced Disease
Interventions: DRUG: Abemaciclib|DRUG: Abemaciclib|DRUG: Abemaciclib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
Status: ACTIVE_NOT_RECRUITING
Conditions: PreDiabetes|Impaired Glucose Tolerance|Hyperglycemia|Resistance, Insulin
Interventions: DIETARY_SUPPLEMENT: Probiotics|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults
Status: COMPLETED
Conditions: Malaria
Interventions: BIOLOGICAL: PfSPZ Vaccine|BIOLOGICAL: PfSPZ Challenge (7G8) for CHMI|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prehabilitation for Women Undergoing Pre-operative Chemotherapy for Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer|Rehabilitation|Neoadjuvant Therapy|Feasibility Studies
Interventions: COMBINATION_PRODUCT: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study
Status: COMPLETED
Conditions: Systemic Inflammatory Response Syndrome|Oliguria|Renal Impairment
Interventions: DRUG: Sodium bicarbonate|DRUG: Sodium chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pars-plana Vitrectomy vs Panretinal Photocoagulation for Severe NPDR
Status: RECRUITING
Conditions: Non Proliferative Diabetic Retinopathy
Interventions: PROCEDURE: Prompt panretinal photocoagulation|PROCEDURE: 25G Pars-plana vitrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FT516 in Subjects With Advanced Hematologic Malignancies
Status: TERMINATED
Conditions: Acute Myelogenous Leukemia|B-cell Lymphoma
Interventions: DRUG: FT516|DRUG: Rituximab|DRUG: Obinutuzumab|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: IL-2|DRUG: Bendamustine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial of Comparative Study of GB221 Pharmacokinetics
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Coprelotamab Injection|DRUG: Trastuzumab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infants of 7-90 Days Age (Late Onset Disease [LOD])
Status: COMPLETED
Conditions: Streptococcus Agalactiae
Interventions: PROCEDURE: Blood sample|OTHER: Vaginal swab sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DRUG: placebo|DRUG: Nebivolol|DRUG: Metoprolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Postoperative Pain Control Between Transarticular VS Periartiucular Multimodal Drug Infiltration in Total Hip Arthroplasty: Double-blinded Randomized Control Trial
Status: COMPLETED
Conditions: Pain, Post Operative|Arthroplasty Complications
Interventions: PROCEDURE: transarticular multimodal drug infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Epicardial Fat Pads Ablation During Coronary Surgery
Status: UNKNOWN
Conditions: Atrial Fibrillation|Ischemic Heart Disease
Interventions: PROCEDURE: Coronary artery bypass grafting|PROCEDURE: Epicardial ganglionated plexi ablation|PROCEDURE: implantable loop recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Pelvic Angle, Femoral Anteversion, and Hip Muscle Strength Ratios in Bladder-bowel Dysfunction
Status: COMPLETED
Conditions: Bladder and Bowel Dysfunction, Femoral Anteversion|Bladder and Bowel Dysfunction, Hip Strength Ratios|Bladder and Bowel Dysfunction, Pelvic Angle
Interventions: OTHER: Scales and measurements for bladder and bowel dysfunction, pelvic angle, proximal hip strength, femoral hip anteversion
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Vitamin D3|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial to Compare the Safety of Two Chemotherapy Plus Trastuzumab Regimens as Adjuvant Therapy for HER2-positive Breast Cancer (Study P05048)
Status: COMPLETED
Conditions: Breast Neoplasm
Interventions: DRUG: doxorubicin, cyclophosphamide, paclitaxel, trastuzumab|DRUG: PLD, cyclophosphamide, trastuzumab, paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol
Status: COMPLETED
Conditions: TBI (Traumatic Brain Injury)
Interventions: DRUG: Melatonin 10 MG Oral Tablet|DRUG: Propofol|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase II Trial of Lapatinib & Capecitabine for Patients With Refractory Advanced Colorectal Adenocarcinoma
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: lapatinib|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a New Inactivated Poliovirus Vaccine in Infants
Status: COMPLETED
Conditions: Poliomyelitis
Interventions: DRUG: IPV|DRUG: Low dose Sabin-IPV|DRUG: Low dose adjuvanted Sabin-IPV|DRUG: Middle dose Sabin-IPV|DRUG: Middle dose adjuvanted Sabin-IPV|DRUG: High dose Sabin-IPV|DRUG: High dose adjuvanted Sabin-IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hospitalization or Outpatient ManagEment of Patients With SRAS-CoV-2 Infection - Revised HOME-CoV Score Study
Status: COMPLETED
Conditions: Coronavirus Infection
Interventions: OTHER: revised HOME-CoV score
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Based on Medical Records That Looks at the Characteristics of Idiopathic Pulmonary Fibrosis Patients Grouped by the Type of Medication They Are Taking
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Nintedanib|DRUG: Pirfenidone|OTHER: Untreated Cohort
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dyadic Pain Management Program for Older Adults and Informal Caregivers With Chronic Pain
Status: UNKNOWN
Conditions: Chronic Pain
Interventions: OTHER: dyadic pain management program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Identification of Risk Factors for Acute Coronary Events by OCT After STEMI and NSTEMI in Patients With Residual Non-flow Limiting Lesions
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Acute Coronary Syndrome|Coronary Artery Disease
Interventions: DEVICE: Coronary Optical Coherence tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Prospective, Non-Randomized Pivotal Clinical Investigation to Demonstrate the Safety and Performance of the TrueCross Single-Use Microcatheter
Status: COMPLETED
Conditions: Coronary Artery Disease Obliterative|Chronic Total Occlusion (CTO)
Interventions: DEVICE: Microcatheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer
Status: WITHDRAWN
Conditions: Pulmonary Embolism|Lung Cancer
Interventions: DIAGNOSTIC_TEST: CTPA (computed tomography pulmonary angiography)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries
Status: COMPLETED
Conditions: Lumbar Erector Spinae Plane Block|Pericapsular Nerve Group Block (PENG Block)
Interventions: PROCEDURE: Ultrasound guided L-ESPB and PENG block using Bupivacaine|DRUG: Postoperative conventional analgesia in form of Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment
Status: UNKNOWN
Conditions: Henoch-Schönlein Purpura Nephritis
Interventions: DRUG: Glycosides Of Tripterygium Wilfordii Hook(GTW)|DRUG: Sulfotanshinone Sodium Injection|DRUG: Chinese herbs based on syndrome differentiation|DRUG: Prednisone Acetate Tablets|DRUG: Benazepril Hydrochloride Tablets|DRUG: Low Molecular Weight Heparin Calcium Injection|DRUG: Dipyridamole Tab 25 MG|DRUG: Chinese medicine placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A MAD Study of TT301/MW189 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Adult Volunteers
Interventions: DRUG: 0.075mg/kg TT301/MW189|DRUG: 0.15mg/kg TT301MW189|DRUG: 0.25mg/kg TT301/MW189|DRUG: 0.30mg/kg TT301/MW189|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-dose Theophylline as Anti-inflammatory Enhancer in Severe Chronic Obstructive Pulmonary Disease
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: theophylline|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study to Compare a 4% Dimethicone Foam and Nix Cream Rinse (1% Permethrin) in the Control of Head Lice
Status: COMPLETED
Conditions: Head Lice
Interventions: OTHER: 4% dimethicone foam|OTHER: 1% permethrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closing Uterine Incision During C-section Using Barbed Suture (Stratafix) or Vicryl Suture.
Status: COMPLETED
Conditions: Cesarean Section
Interventions: DEVICE: Stratafix suture|DEVICE: Vicryl suture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Vaginal Adenocarcinoma|Advanced Vaginal Adenosquamous Carcinoma|Advanced Vaginal Squamous Cell Carcinoma|Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Squamous Cell Carcinoma|Stage IB2 Cervical Cancer AJCC v6 and v7|Stage II Cervical Cancer AJCC v7|Stage II Vaginal Cancer AJCC v6 and v7|Stage IIA Cervical Cancer AJCC v7|Stage IIB Cervical Cancer AJCC v6 and v7|Stage III Vaginal Cancer AJCC v6 and v7|Stage IIIB Cervical Cancer AJCC v6 and v7|Stage IV Vaginal Cancer AJCC v6 and v7|Stage IVA Cervical Cancer AJCC v6 and v7|Stage IVA Vaginal Cancer AJCC v6 and v7|Unresectable Vaginal Carcinoma|Vaginal Adenocarcinoma|Vaginal Adenosquamous Carcinoma|Vaginal Carcinoma|Vaginal Squamous Cell Carcinoma, Not Otherwise Specified
Interventions: RADIATION: Brachytherapy|DRUG: Cisplatin|RADIATION: External Beam Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|RADIATION: Radiation Therapy|DRUG: Triapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microbiome Derived Metabolism and Pharmacokinetics
Status: RECRUITING
Conditions: Microbial Colonization
Interventions: DRUG: Tolcapone 100 MG|DRUG: Duloxetine 20 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: PanDirect: Self-care Tools and Telephone Coaching for Depression and Anxiety During Pandemics
Status: COMPLETED
Conditions: Mental Health Wellness 1|Coaching|Pandemic|Depression, Anxiety|Self-care Tools
Interventions: BEHAVIORAL: self-care tools|BEHAVIORAL: lay telephone coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders: the ENGAGE Pilot Study
Status: COMPLETED
Conditions: Mobility Limitation
Interventions: OTHER: Physical Activity Intervention|OTHER: Healthy Aging Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Fat-Induced Insulin Resistance
Status: RECRUITING
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance|Insulin Sensitivity
Interventions: DRUG: Intralipid, 20% Intravenous Emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Conversion Study From Epoetin Alfa to Monthly Peginesatide Injection in Patients With Chronic Kidney Disease on Dialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|Anemia
Interventions: DRUG: Epoetin|DRUG: Peginesatide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical and Magnetic Resonance Imaging Evaluation of Micro Fragmented Adipose Tissue Injection Combined With Bone Marrow Stem Cells on Healing of Temporomandibular Joint Internal Disc Derangement Without Reduction
Status: NOT_YET_RECRUITING
Conditions: Temporomandibular Joint Disorders
Interventions: PROCEDURE: Micro fragmented adipose tissue mixed with bone marrow stem cells|PROCEDURE: Bone Marrow stem cells aspirate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Open-label, Long-term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation|Chronic Constipation
Interventions: DRUG: Linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TENS Used for Pain Management During Office Cystoscopy Botox Injections
Status: RECRUITING
Conditions: Overactive Bladder
Interventions: DEVICE: Active TENS|DEVICE: Sham TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hypnosis for Symptom Management in Elective Orthopedic Surgery
Status: COMPLETED
Conditions: Hypnosis|Perioperative Care|Knee Arthroplasty, Total|Postoperative Pain|Postoperative Complications
Interventions: BEHAVIORAL: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Phase I/II of Oral Vorinostat Combination With Erlotinib in NSCLC Patients With EGFR Mutations With DP After Erlotinib.
Status: TERMINATED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Vorinostat plus Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Status: RECRUITING
Conditions: Advanced Liver Cancers
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab 15 mg/kg|DRUG: Tiragolumab|DRUG: Tocilizumab|DRUG: TPST-1120|DRUG: Tobemstomig 2100 mg|DRUG: Bevacizumab 10 mg/kg|DRUG: Tobemstomig 600 mg|DRUG: Tobemstomig 1200 mg|DRUG: ADG126|DRUG: IO-108 1800 mg|DRUG: NKT2152|DRUG: IO-108 1200 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab for Acute Chest Syndrome
Status: RECRUITING
Conditions: Sickle Cell Disease|Acute Chest Syndrome
Interventions: DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT