pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Testing an HIV Prevention Intervention for Psychiatric Patients in Brazil
Status: COMPLETED
Conditions: HIV Infection|HIV Infections
Interventions: BEHAVIORAL: HIV Prevention Intervention - Project PRISSMA - HIV I have my eye on you|BEHAVIORAL: Health Promotion Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.
Status: TERMINATED
Conditions: Cataract
Interventions: DEVICE: Model DIU|DEVICE: Model DFW|DEVICE: Model ZCT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Magnesium Sulphate as an Adjuvant to Levobupivacaine in Ultra-sound Guided Transversus Abdominis Plan Block in Pediatric Abdominal Cancer Surgery
Status: RECRUITING
Conditions: Postoperative Pain
Interventions: PROCEDURE: ultra-sound guided transversus abdominis plan block|DRUG: magnesium sulphate& levobupivacaine|DRUG: Levobupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: De-Adoption of Beta-Blockers in Patients With Stable Ischemic Heart Disease
Status: RECRUITING
Conditions: Stable Ischemic Heart Disease|Coronary Artery Disease|Beta-blocker Therapy
Interventions: OTHER: Medical Assessment|OTHER: Quality of Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: INFUSE™ BONE GRAFT/CORNERSTONE-SR™ Allograft Ring/ATLANTIS™ Anterior Cervical Plate- Pilot Study
Status: COMPLETED
Conditions: Degenerative Cervical Disc Disease
Interventions: DEVICE: INFUSE™ Bone Graft/CORNERSTONE-SR™ /ATLANTIS™|DEVICE: Autogenous bone/CORNERSTONE-SR™ /ATLANTIS™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGF
Status: TERMINATED
Conditions: Retinal Vein Occlusion (RVO)|Macular Edema
Interventions: DRUG: Ozurdex implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Mobile Health Solution for Homework During CBT
Status: COMPLETED
Conditions: Anxiety|Depression|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy (CBT)|BEHAVIORAL: CBT+App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Pharmacokinetics of an Anti-Inflammatory Therapeutic Antibody (MABp1) in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: T2-18C3 therapeutic antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal Pain in Cancer Patients,
Status: RECRUITING
Conditions: Perineal Pain
Interventions: PROCEDURE: US assisted caudal epidural pulsed radiofrequency
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 3 Study of UGN-103 for Treatment of Patients With Low-grade Intermediate-risk Non-muscle Invasive Bladder Cancer
Status: RECRUITING
Conditions: Bladder Cancer|Urothelial Carcinoma|Urothelial Carcinoma Bladder
Interventions: DRUG: UGN-103
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Evaluate the Performance and Safety of YVOIRE Volume Plus for Improvement of Mid-face Volume
Status: UNKNOWN
Conditions: Midface Volume Deficit
Interventions: DEVICE: YVOIRE volume plus|DEVICE: Restylane Lyft with Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Whey Protein Effect on Glycaemic and Appetite Responses in T2D
Status: UNKNOWN
Conditions: Type II Diabetes Mellitus|Glucose Metabolism Disorders|Metabolic Diseases
Interventions: DIETARY_SUPPLEMENT: Whey Protein|DIETARY_SUPPLEMENT: Hydrolysed Protein|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Self-expandable Metallic Stent Versus Multiple Plastic Stents in Post Orthotopic Liver Transplantation Biliary Stenosis
Status: COMPLETED
Conditions: Biliary Anastomotic Stenosis|Biliary Stricture
Interventions: DEVICE: Self-expandable metalic stent|DEVICE: Multiple plastic stents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Consciousness Variation of Deep Brain and Transcranial Magnetic Stimulation for Disorders of Consciousness Patients
Status: UNKNOWN
Conditions: Consciousness Disorders
Interventions: DEVICE: deep brain stimulation|DEVICE: transcranial magnetic stimulation|OTHER: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: tVNS Responsiveness Testing With Pupil Size
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: PROCEDURE: Unilateral tVNS stimulation|PROCEDURE: Bilateral tVNS stimulation|PROCEDURE: Unilateral Sham stimulation|PROCEDURE: Bilateral Sham stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Periocular Drug Injection in CATaract Surgery
Status: UNKNOWN
Conditions: Macular Edema|Cystoid Macular Edema|Retinal Disease|Cataract|Lens Diseases|Eye Diseases
Interventions: DRUG: Bromfenac|DRUG: Dexamethasone|DRUG: Triamcinolone Acetonide|DRUG: Ketorolac-Phenylephrine Ophthalmic 0.3%-1% Intraocular Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML
Status: WITHDRAWN
Conditions: Recurrent Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Alvocidib Hydrochloride|DRUG: Decitabine|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Chemotherapy Response Assessment by Combined PET-MRI in Borderline and Locally Advanced Pancreatic Adenocarcinoma.
Status: UNKNOWN
Conditions: Pancreatic Adenocarcinoma
Interventions: DEVICE: PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of the Minimally Invasive VenTouch™ System in the Treatment of Functional Mitral Valve Regurgitation (FMR)
Status: UNKNOWN
Conditions: Functional Mitral Regurgitation
Interventions: DEVICE: VenTouch System Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE
Status: RECRUITING
Conditions: Hepatocellular Carcinoma (HCC)
Interventions: DRUG: Durvalumab|DRUG: Bevacizumab|PROCEDURE: Transarterial Radioembolization (TARE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: RADIATION: Single-fraction stereotactic body radiation therapy (SBRT)|RADIATION: Multiple-fraction stereotactic body radiation therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reminiscence-Based Life Review on Copying With Existential Suffering Among Older Cancer Survivors
Status: RECRUITING
Conditions: Existential Suffering|Meaning of Life|Cognitive Function|Psychological Distress|Social Support
Interventions: BEHAVIORAL: Reminiscence-Based Life Review
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Targeted Physiotherapeutic Treatment for Aromatase Inhibitor-associated Musculoskeletal Pain in Breast Cancer Survivors
Status: COMPLETED
Conditions: Musculoskeletal Pain
Interventions: OTHER: Physiotherapeutic treatment and medical care|OTHER: medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of a Single Dose of Wild Blueberries on Mood and Cognition in Healthy Young Adults
Status: COMPLETED
Conditions: Mood|Affect|Cognition
Interventions: DIETARY_SUPPLEMENT: Wild blueberry powder|DIETARY_SUPPLEMENT: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Half-normal Saline in Idiopathic Left Ventricular Outflow Tract Arrhythmias Ablation
Status: SUSPENDED
Conditions: Ventricular Arrythmia
Interventions: DRUG: Half-normal saline|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: The Effect of Warm Compress Therapy Using the TearRestore Eyelid Warming Mask on Meibomian Gland Function
Status: UNKNOWN
Conditions: Meibomian Gland Dysfunction
Interventions: DEVICE: Tear Restore Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes
Status: COMPLETED
Conditions: Presbyopia
Interventions: DEVICE: AcuFocus Corneal Inlay ACI 7000PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy
Status: TERMINATED
Conditions: Hen Egg Allergy
Interventions: BIOLOGICAL: AR201 powder|BIOLOGICAL: Placebo powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Continuous Glucose Monitoring in Individuals With Newly Diagnosed Type 2 Diabetes
Status: NOT_YET_RECRUITING
Conditions: Diabetes Type 2
Interventions: DEVICE: Continous Glucose Monitoring|OTHER: Self monitoring blood glucose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: DRUG: asparaginase|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: methotrexate|DRUG: prednisone|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Personal Patient Profile - Prostate (P3P) II: Effectiveness-Implementation Trial in Diverse Health Care Networks
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: Personal Patient Profile - Prostate (P3P)|BEHAVIORAL: Standard prostate cancer information websites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: "The Effectiveness of Transvertebral Magnetic Neuromodulation in Patients With Detrusor Overactivity"
Status: UNKNOWN
Conditions: Overactive Bladder
Interventions: DEVICE: Transvertebral magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Alleviating Effects Against High Intraocular Pressure by Oral Intake of Cordyceps Cicadae Mycelia
Status: COMPLETED
Conditions: Supplement
Interventions: DIETARY_SUPPLEMENT: Cordyceps Cicadae Mycelia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Glycemic Gap Versus Admission Plasma Glucose Level As Predictors of ICU Out Comes in Type 2 Diabetic Patients With Acute Heart Failure
Status: UNKNOWN
Conditions: Assess the Relation Between Glycemic Gab and Adverse Clinical Outcomes in Diabetic Patients Who Hospitalized With Heart Failure
Interventions: DEVICE: glycemic gap
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Waferless One Stage Segmental Lefort I Maxillary Positioning in Transverse Deficiency
Status: UNKNOWN
Conditions: Lefort I Osteotomy
Interventions: PROCEDURE: Accuracy of planned transverse Maxillary distance using Mimics software after fixation using Patient specific implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC61in Subjects With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: ASC61 200 mg 1|DRUG: ASC61 200 mg 2|DRUG: ASC61 300 mg|DRUG: ASC61 400 mg|DRUG: ASC61 600 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biological and Clinical Measurements Following Systemic Leakage When a Citrate or Heparin Lock is Used
Status: COMPLETED
Conditions: Acute Renal Insufficiency
Interventions: DRUG: citrate 4%|DRUG: unfractionated heparin|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Efficacy Study of TACE to Treat Hepatocellular Carcinoma After Operation
Status: UNKNOWN
Conditions: Carcinoma, Hepatocellular|Neoplastic Cells, Circulating
Interventions: PROCEDURE: TACE|DRUG: Epirubicin|DRUG: lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Role of Acupuncture Treatment in Neuronal and Network Dysfunction in Patients With Vascular Cognitive Impairment
Status: UNKNOWN
Conditions: Vascular Cognitive Impairment
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Biomarker Study of Pts With Metastatic ccRCC Undergoing Sequential Therapy With 1st Line Sunitinib and 2nd Line Axitinib
Status: UNKNOWN
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety & Tolerability Study of CTP-499 in Patients With Moderate Chronic Kidney Disease
Status: COMPLETED
Conditions: Stage 3 Chronic Kidney Disease
Interventions: DRUG: CTP-499|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparsion of MCkenzie and Mulligan Exercise in Patients With Non-Specific Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: BEHAVIORAL: Mckenzie Exercises|BEHAVIORAL: Mulligan Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DRUG: TV-45070|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Upper Urinary Tract Stones With a Diameter≤2cm by Intelligent Pressure-controlled Flexible Ureteroscope
Status: UNKNOWN
Conditions: Urinary Calculi
Interventions: DEVICE: Flexible ureteroscope with intelligent control of renal pelvic pressure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease|End Stage Renal Disease|Coronary Artery Calcification|Vascular Calcification|Calcification|Cardiovascular Disease|Chronic Renal Failure|Hyperparathyroidism|Kidney Disease|Nephrology|Secondary Hyperparathyroidism
Interventions: DRUG: cinacalcet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessing the Role of Cariprazine in Improving Cognition in Euthymic Bipolar Patients
Status: RECRUITING
Conditions: Bipolar I Disorder|Cognitive Impairment
Interventions: DRUG: Cariprazine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Bladder Cancer|Brain and Central Nervous System Tumors|Breast Cancer|Esophageal Cancer|Extragonadal Germ Cell Tumor|Gastric Cancer|Lung Cancer|Ovarian Cancer|Prostate Cancer
Interventions: DRUG: lapatinib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Taste and Levels in Blood Plasma of BMS-986165 When Taken as Different Formulations by Healthy Adult Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: BMS-986165 Tablet formulation 1|DRUG: BMS-986165 Tablet formulation 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms Malignant|Liver Metastases
Interventions: RADIATION: Liver radiation therapy|DRUG: Nivolumab Injection [Opdivo]|DRUG: Ipilimumab Injection [Yervoy]|DRUG: CMP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effect of Ha44 Gel on the Electrocardiogram in Healthy Volunteers
Status: COMPLETED
Conditions: Pediculosis
Interventions: DRUG: Ha44|DRUG: Ha44 Placebo|DRUG: Moxifloxacin Placebo|DRUG: Moxifloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial on Acupuncture Adjuvant Treatment in the Pain After the Surgery of Gastrointestinal Carcinoma
Status: COMPLETED
Conditions: Gastrointestinal Carcinoma|Pain
Interventions: DEVICE: Acupuncture therapy|PROCEDURE: Laparoscopic Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trifluridine/Tipiracil Combined With Cetuximab in the Treatment of Third-line and Above RAS/BRAF Wild-type mCRC
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: Cetuximab|DRUG: Trifluridine/Tipiracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8
Interventions: BEHAVIORAL: Hypnosedation|OTHER: Questionnaire Administration|BEHAVIORAL: Verbal Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Cabozantinib for Advanced Urothelial Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma|Urethral Neoplasms|Urinary Bladder Neoplasms|Kidney Neoplasms
Interventions: DRUG: Cabozantinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preschool Wheeze: Inflammation/Infection Guided Management
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Beclometasone|DRUG: Co-amoxiclav|DRUG: Azithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Flavanoids in Essential Hypertension, Type 2 Diabetes and Healthy Persons
Status: COMPLETED
Conditions: Vascular Complications, Diabetic
Interventions: DIETARY_SUPPLEMENT: flavanols (subgroup of polyphenols, subgroup of phenolics, natural substances)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Novel Technique in Closure of Mesenteric Defects After Laparoscopic Roux-en-Y Gastric Bypass and Its Effect on Internal Hernia: a Case-control Study
Status: COMPLETED
Conditions: Bariatric Surgery
Interventions: OTHER: Closure of mesenteric defects using glue
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Vortioxetine in the Treatment of Depression Associated With Head and Neck Cancers Undergoing Radiotherapy
Status: UNKNOWN
Conditions: Radiation Injuries
Interventions: DRUG: Vortioxetine 10 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: First-in-Human, Multiple Part Clinical Study of JNT-517 in Healthy Participants and in Participants With Phenylketonuria
Status: RECRUITING
Conditions: Phenylketonuria
Interventions: DRUG: JNT-517 Suspension|DRUG: Placebo Suspension|DRUG: JNT-517 Tablet|DRUG: Placebo Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria
Status: RECRUITING
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: OMS906 study drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lysine Clonixinate, Ketorolac and Metamizole Sodium in Scorpion Stings
Status: COMPLETED
Conditions: Scorpion Stings|Pain|Analgesic
Interventions: DIAGNOSTIC_TEST: Visual Analogue Scale for pain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Test the Safety and Tolerability of Long-term UCB0107 Administration in Study Participants With Progressive Supranuclear Palsy
Status: ACTIVE_NOT_RECRUITING
Conditions: Progressive Supranuclear Palsy
Interventions: DRUG: UCB0107 (bepranemab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of the Coadministration of ANS-6637 and Ethanol
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: ANS-6637 Oral Tablet|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery
Status: TERMINATED
Conditions: Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: DIETARY_SUPPLEMENT: defined green tea catechin extract|OTHER: placebo|OTHER: immunohistochemistry staining method|OTHER: immunoenzyme technique|OTHER: questionnaire administration|PROCEDURE: therapeutic conventional surgery|OTHER: high performance liquid chromatography|OTHER: mass spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Enhancing the Effectiveness of Home-delivery Based Produce Prescription Program Implementation Strategies
Status: NOT_YET_RECRUITING
Conditions: Nutritional Deficiency in Pregnancy
Interventions: BEHAVIORAL: Produce Prescription Program (PPRx) Standard|BEHAVIORAL: Smartphone App
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Trial of Perioperative CV301 Vaccination in Combination With Nivolumab and Systemic Chemotherapy for Metastatic CRC
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: mFOLFOX6|BIOLOGICAL: MVA-BN-CV301|BIOLOGICAL: FPV-CV301|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Informed Consent: a New Solution to Improve and Objectively Test the Patient Understanding of Complex Surgical Procedures Proposals
Status: RECRUITING
Conditions: Spine Disease|Urologic Diseases
Interventions: OTHER: active informed consent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Econazole Foam 1% in Athlete's Foot
Status: COMPLETED
Conditions: Tinea Pedis|Athlete's Foot
Interventions: DRUG: Econazole Nitrate Cream 1%|DRUG: Econazole Nitrate Foam 1%|DRUG: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of the TSP Crosser System for Transseptal Access and Left Atrial Catheter Navigation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: TSP Crosser Transseptal Access System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bilateral Monofocal Versus Monofocal-EDOF IOL Implantation: Quality of Vision Comparison
Status: NOT_YET_RECRUITING
Conditions: Cataract
Interventions: DEVICE: cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of CXCR5 Modified EGFE Chimeric Antigen Receptor Autologous T Cells in EGFR- Positive Patients With Advanced Non-small Cell Lung Cancer
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: CXCR5 modified EGFR Chimeric Antigen Receptor Autologous T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Farnesyl Transferase Inhibitor, R115777, in Combination With Topotecan (NYU 99-32)
Status: UNKNOWN
Conditions: Cancer
Interventions: DRUG: R115777 (farnesyl transferase inhibitor)|DRUG: Topotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vascular Effect of Tibolone in the Brachial Artery
Status: COMPLETED
Conditions: Menopause
Interventions: DRUG: Tibolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: the Effects of YangXinShi (YXS) on the Quality of Life and Exercise Tolerance in Patients With Chronic Heart Failure
Status: UNKNOWN
Conditions: Chronic Heart Failure
Interventions: DRUG: YanXinShi placebo pills|DRUG: YanXinShi pills|DRUG: Trimetazidine pills|DRUG: YanXinShi and Trimetazidine pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: What Makes a Cup, a Cup? Generalizing Novel Words
Status: RECRUITING
Conditions: Healthy
Interventions: BEHAVIORAL: Modality - 3D-2D|BEHAVIORAL: Modality - 2D-3D|BEHAVIORAL: Modality - 2D-2D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Zenith® p-Branch® Endovascular Graft Pivotal Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Aortic Aneurysm Abdominal
Interventions: DEVICE: Zenith® p-Branch® in combination with the Atrium iCAST™ covered stents
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement
Status: COMPLETED
Conditions: Atherosclerosis
Interventions: DRUG: ticagrelor|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Effectiveness of Ganciclovir Plus Interferon Beta in Preventing the Return of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS
Status: COMPLETED
Conditions: Cytomegalovirus Retinitis|HIV Infections
Interventions: DRUG: Interferon beta-1b|DRUG: Ganciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prospective Study on the Clinical Prognosis of Bilateral Central Lymph Node Dissection in the Patients With Unilateral Thyroid Papillary Carcinoma
Status: UNKNOWN
Conditions: Thyroid Papillary Carcinoma
Interventions: PROCEDURE: surgery：BCND（bilateral central lymph node dissection）|PROCEDURE: surgery：UCND（unilateral central lymph node dissection）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interleukin-1 (IL-1) Blockade in Acute Myocardial Infarction (VCU-ART3)
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DRUG: Anakinra 100 mg|DRUG: Anakinra 100 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cholesterol-Lowering Atherosclerosis Study (CLAS)
Status: COMPLETED
Conditions: Arterial Occlusive Diseases|Cardiovascular Diseases|Carotid Artery Diseases|Cerebral Arteriosclerosis|Cerebrovascular Disorders|Coronary Arteriosclerosis|Coronary Disease|Heart Diseases|Myocardial Ischemia|Atherosclerosis
Interventions: DRUG: colestipol|DRUG: niacin|BEHAVIORAL: diet, fat-restricted
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study of Intradermal Administration of PCEC Rabies Vaccine
Status: COMPLETED
Conditions: Rabies Prevention|Rabies Exposure
Interventions: BIOLOGICAL: PCEC rabies vaccine given intradermally|BIOLOGICAL: PCEC rabies vaccine administered intramuscularly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Determination of Abnormal Fetal Growth or Amniotic Fluid With Third Trimester Ultrasounds in Uncomplicated Pregnancies: A Randomized Trial
Status: COMPLETED
Conditions: Uncomplicated Pregnancy|Abnormal Fetal Growth or Fluid
Interventions: DEVICE: Clinically-indicated ultrasound|DEVICE: Serial third trimester ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Using Smart Glasses Integrated Ultrasonography on Radial Artery Catheterization
Status: COMPLETED
Conditions: Catheterization|Cannulation
Interventions: OTHER: Radial artery catheterization with USG|OTHER: Radial artery catheterization with smart glasses integrated UGG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hepatic Arterial Infusion Oxaliplatin + 5FU, Leucovorin, and Bevacizumab +/- Cetuximab
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: HAI Oxaliplatin|DRUG: 5-FU|DRUG: Bevacizumab|DRUG: Cetuximab|DRUG: Leucovorin|DRUG: 5-FU|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Allium Extracts on the Intestinal Microbiota in Healthy Resident Volunteers.
Status: COMPLETED
Conditions: Intestinal Bacteria Flora Disturbance
Interventions: DIETARY_SUPPLEMENT: Garlic and onion concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Active Systemic Lupus Erythematosus
Interventions: BIOLOGICAL: Anifrolumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Status: SUSPENDED
Conditions: Down Syndrome|Recurrent B Acute Lymphoblastic Leukemia
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|BIOLOGICAL: Blinatumomab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Etoposide|DRUG: Hydrocortisone Sodium Succinate|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Methotrexate|BIOLOGICAL: Nivolumab|DRUG: Pegaspargase|DRUG: Thioguanine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aqueous Humor Dynamics of NCX 470 Ophthalmic Solution
Status: RECRUITING
Conditions: Open Angle Glaucoma
Interventions: DRUG: NCX 470|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Impairment Specific Exercises for Balance and Fall Risk in Community-Living Older Adults at Risk: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Balance, Postural|Exercise Therapy
Interventions: OTHER: Matched: Targeted (specific) balance exercise interventions|OTHER: Mismatched: Untargeted (non-specific) balance exercise interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy
Status: TERMINATED
Conditions: Hepatic Encephalopathy|Cirrhosis, Liver
Interventions: BIOLOGICAL: RBX7455|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
Status: RECRUITING
Conditions: Overweight or Obesity
Interventions: BEHAVIORAL: NDPP-NextGen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A 6 Month Study to Compare the Metabolic Effects of Paliperidone ER and Olanzapine in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: olanzapine|DRUG: paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Tofersen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I/II Study of [124I]mIBG PET/CT in Neuroblastoma
Status: COMPLETED
Conditions: Metastatic Neuroblastoma
Interventions: DRUG: [124I]meta-Iodobenzylguanidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Pyrotinib in Patients With HER2-positive Solid Tumors
Status: UNKNOWN
Conditions: Breast Cancer|Gastric Cancer|Solid Tumors|NSCLC
Interventions: DRUG: Pyrotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Survival imProvement in Lung cancEr iNduced by DenOsUmab theRapy
Status: TERMINATED
Conditions: Lung Cancer Non-small Cell Stage IV
Interventions: DRUG: Denosumab|OTHER: None, standard chemotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of PK and Tolerability of MSB11022 Administered by AI or PFS
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Polyarticular Juvenile Idiopathic Arthritis|Psoriatic Arthritis|Ankylosing Spondylitis|Crohn Disease|Ulcerative Colitis|Plaque Psoriasis|Pediatric Plaque Psoriasis|Pediatric Crohns Disease|Hidradenitis Suppurativa|Non-infectious Uveitis
Interventions: DRUG: 40 mg MSB11022|DRUG: 40 mg MSB11022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Prospective Study on the Feasibility of Plasma FLT3-Ligand Assay to Achieve a First Estimate of Its Prognostic Value on the Outcome of Patients Treated Intensively for Acute Leukemia
Status: COMPLETED
Conditions: Acute Leukemia
Interventions: OTHER: Non Interventional study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Functional Magnetic Resonance Imaging (fMRI) of Anosognosia in Amnestic Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
Status: COMPLETED
Conditions: Anosognosia|Alzheimer's Disease|Mild Cognitive Impairment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Probiotics on Improving the Gastrointestinal Function and Intestinal Bacterial Flora
Status: UNKNOWN
Conditions: Gastrointestinal Function|Intestinal Bacteria Flora
Interventions: DIETARY_SUPPLEMENT: probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: T-DM1 and Osimertinib Combination Treatment to Target HER2 Bypass Track Resistance in EGFR Mutation Positive NSCLC
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Trastuzumab emtansine|DRUG: Osimertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: New Ovarian Stimulation With Random Start, Use of Progestin Protocol for Oocyte Donors
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Desogestrel early follicular phase|DRUG: Desogestrel medium follicular phase|DRUG: Desogestrel ovulatory phase|DRUG: Desogestrel late follicular phase|DRUG: Desogestrel luteal phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combining rTMS With Varenicline to Prevent Smoking Lapse in Schizophrenia
Status: WITHDRAWN
Conditions: Tobacco Use Disorder|Schizophrenia|Cognitive Functioning|Craving
Interventions: DEVICE: Active rTMS (20Hz)|DEVICE: Sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial for Ankle Fracture Pain Control
Status: RECRUITING
Conditions: Ankle Fractures
Interventions: DRUG: Long-Acting Local Anesthesia|DRUG: Regional Anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder
Status: COMPLETED
Conditions: Bipolar Disorder|Mood Disorders
Interventions: DRUG: Placebo|DRUG: Quetiapine|DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prostatic Arterial Embolization With SQUID (Ethylene Vinyl Alcohol Copolymer )
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Hyperplasia, Benign
Interventions: PROCEDURE: SQUID (Ethylene Vinyl Alcohol Copolymer ) administred to the participant with the intervention Prostatic Arterial Embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer
Status: COMPLETED
Conditions: Small Cell Lung Cancer|Extensive-stage Small Cell Lung Cancer
Interventions: RADIATION: Thoracic Radiation Therapy|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacogenomics for Better Treatment of Fungal Infections in Cancer
Status: NOT_YET_RECRUITING
Conditions: Fungal Infection|Haematological Malignancy|Blood Cancer|Infectious Disease
Interventions: OTHER: genotype-directed dosing with dosing software based on therapeutic drug monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Value of Cabergoline and Low Dose Aspirin in Poor Responders Undergoing ICSI-ET With GnRH Agonist Flare-Up-Protocol
Status: UNKNOWN
Conditions: Invitro Fertilization
Interventions: DRUG: cabergoline|DRUG: Aspirin|DRUG: GnRH agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Controlled Human Pneumococcal Infection Model (PIM) Study
Status: COMPLETED
Conditions: Streptococcus Pneumoniae Infection
Interventions: BIOLOGICAL: Sp_6B|DRUG: Amoxicillin 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Oral Sildenafil With Digital Therapeutic Iontophoresis of Sodium Nitroprussiate in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: sildenafil|DRUG: nitroprussiate iontophoresis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RefleXion PET/CT Imaging Performance in Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Carcinoma
Interventions: PROCEDURE: Computed Tomography|OTHER: Fluorine F 18 Piflufolastat|DEVICE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of Amway Herbal Drink to Improve Skin Anti-aging
Status: RECRUITING
Conditions: Skin Laxity|Skin Lines
Interventions: DIETARY_SUPPLEMENT: Amway Herbal Drink|DIETARY_SUPPLEMENT: Placebo Drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: RCT Comparing Ion Levels and Clinical Outcomes of A-Class BFH to Metal on Polyethylene Total Hip Replacement
Status: COMPLETED
Conditions: Hip Joint|Osteoarthritis|Arthroplasty
Interventions: DIAGNOSTIC_TEST: Blood metal ion levels
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Dialysis of Sugammadex in Participants With Severe Renal Impairment (Study 19.4.333) (P05773)
Status: COMPLETED
Conditions: Neuromuscular Blockade
Interventions: DRUG: sugammadex|DRUG: Rocuronium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT