pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Primary and Booster Vaccination Study With a Pneumococcal Vaccine in HIV Infected, HIV Exposed Uninfected and HIV Uninfected Children 6 to 10 Weeks of Age.
Status: COMPLETED
Conditions: Infections, Streptococcal
Interventions: BIOLOGICAL: Pneumococcal vaccine GSK1024850A|BIOLOGICAL: Tritanrix-HepB/Hib|BIOLOGICAL: measles|BIOLOGICAL: Rotarix|BIOLOGICAL: Local OPV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of a Novel Method for Integrating Insulin Delivery and Glucose Sensing in Adipose Tissue of Diabetic Patients
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: Glucose measurement at the sc. insulin delivery site
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using Technology to Improve Function for Older Latinos With Disabilities in Underserved Areas
Status: NOT_YET_RECRUITING
Conditions: Aging|Disability Physical
Interventions: BEHAVIORAL: Viviendo las Ventajas de la Asistencia Tecnológica|OTHER: Attention calls
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Combination of Ginkgo Extract and Ginseng Extract in Children With ADHD(Attention Deficit Hyperactivity Disorder)
Status: COMPLETED
Conditions: Mental Disorders
Interventions: DRUG: YY-162|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Effects of TIVA vs VIMA on Content of GSK-3beta in Leucocytes in On-pump Patients
Status: TERMINATED
Conditions: Glycogen Synthase Kinase 3
Interventions: DRUG: Sevoflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Intervention to Improve Quality of Sleep of Palliative Patient Carers in the Community: Clinical Trial
Status: COMPLETED
Conditions: Music Therapy|Caregivers|Sleep|Palliative Care
Interventions: OTHER: Music Therapy|OTHER: simulation with therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use of the Motivational Interviewing in the Treatment of Smokers in Groups in Primary Health Care
Status: COMPLETED
Conditions: Smoking, Tobacco|Smoking Cessation
Interventions: BEHAVIORAL: Motivational Interviewing|BEHAVIORAL: Traditional cognitive-behavioral approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-Response and Variability of Inhaled Insulin in Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: INH 69 U (low)|DRUG: INH 69 U (high)|DRUG: INH 139 U|DRUG: INH 208 U|DRUG: LIS 18 U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: FFR Versus iFR in Assessment of Hemodynamic Lesion Significance
Status: UNKNOWN
Conditions: Hemodynamics|Coronary Circulation|Tomography, Optical Coherence|Endothelial Cells|Polymorphism, Genetic
Interventions: DEVICE: Fractional flow reserve and instantaneous wave-free ratio
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound Guided Emergency Physician Performed Erector Spinae Nerve Block for Rib Fracture Analgesia
Status: NOT_YET_RECRUITING
Conditions: Rib Fractures
Interventions: DRUG: ESP block with bupivacaine|OTHER: Saline control/sham injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Initiation of Diet in Esophageal Varices After Ligation (IDEAL) Study
Status: UNKNOWN
Conditions: Liver Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Early Diet Group|DIETARY_SUPPLEMENT: Late Diet Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Iron Supplementation Among Low-Income Postpartum Women
Status: COMPLETED
Conditions: Anemia
Interventions: BEHAVIORAL: Daily iron supplements of 65 mg a day for 3 months|BEHAVIORAL: Universal anemia screening and treatment|BEHAVIORAL: Selective anemia screening and treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients
Status: UNKNOWN
Conditions: Hypertension Pulmonary Secondary Heart Failure|Right Sided Heart Failure With Normal Ejection Fraction|Heart Failure With Normal Ejection Fraction
Interventions: DRUG: Levosimendan 2.5 mg/ml Injectable Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Breast Cancer Active Surveillance, Alternative Option, Aspirin Included
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Aspirin Low Dose|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Low Level Laser Therapy in Ulnar Neuropathy at the Elbow
Status: COMPLETED
Conditions: Ulnar Nerve Entrapment at Elbow
Interventions: OTHER: Low-level laser therapy|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections
Status: COMPLETED
Conditions: Complicated Urinary Tract Infections
Interventions: DRUG: Eravacycline|DRUG: Ertapenem|DRUG: Placebo|DRUG: Levofloxacin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long Term Safety Study of Nasalfent (Fentanyl Citrate Nasal Spray) for Treatment of Breakthrough Cancer Pain
Status: COMPLETED
Conditions: Cancers, Pain
Interventions: DRUG: Fentanyl (Nasalfent, Fentanyl Citrate Nasal Spray)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Investigation of Efficacy and Outcome of a New Medical Device for Treatment of Migraine
Status: TERMINATED
Conditions: Migraine
Interventions: DEVICE: In-house prototype invented by Jan-Erik Juto|DEVICE: In-house prototype invented by Jan-Erik Juto
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Decompression With ELDOA on Lumbar Disc Protrusion Patient
Status: COMPLETED
Conditions: Lumbar Disc Herniation|Spinal Disk Injury|Protrusion
Interventions: OTHER: Control Group|OTHER: Decompression Group|OTHER: ELDOA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: QUantitative Flow Ratio Or Angiography for the assessMent of nOn-culprit Lesions
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Quantitative flow ratio|DIAGNOSTIC_TEST: Assessment of angiographic severity of the stenosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Electroacupuncture on SAP With MODS
Status: UNKNOWN
Conditions: Severe Acute Pancreatitis
Interventions: DEVICE: electroacupuncture treatment|DEVICE: sham electroacupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Oxytocin Nasal Spray for Treatment of Tinnitus
Status: TERMINATED
Conditions: Tinnitus
Interventions: DRUG: Oxytocin|OTHER: Placebo nasal spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Genius Toothbrushes on Periodontal Status of Orthodontic Patients
Status: COMPLETED
Conditions: Periodontal Inflammation|Toothbrushing|Orthodontic Treatment
Interventions: DEVICE: Genius toothbrush|DEVICE: Manual toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Implementation of Asthma Community Home and School Management Program (Asthma CHAMPS)
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Asthma CHAMPS full program|BEHAVIORAL: Asthma CHAMPS Wait List Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Gut Microbiome|Gut Health|Dietary Supplement|L-Phenylalanine|Phenylpropionic Acid
Interventions: DIETARY_SUPPLEMENT: L-Phenylalanine 500 mg Veg Capsule product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluating Effects of Curcumin in Moderate to Severe Asthmatics
Status: WITHDRAWN
Conditions: Asthma
Interventions: DRUG: Curcumin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation
Status: RECRUITING
Conditions: Treatment Resistant Depression|Suicidal Ideation
Interventions: DRUG: Psilocybin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imatinib, Capecitabine, and Cisplatin in Treating Patients With Unresectable or Metastatic Stomach Cancer
Status: COMPLETED
Conditions: Gastric Cancer
Interventions: DRUG: capecitabine|DRUG: cisplatin|DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post Colposcopy Management of ASC-US and LSIL Pap Tests
Status: COMPLETED
Conditions: Cervical Cancer Screening
Interventions: PROCEDURE: Colposcopy|OTHER: Pap test|DIAGNOSTIC_TEST: HPV test
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Making Decisions About Participating in a Cancer Clinical Trial for Patients With Stage II, Stage III, or Stage IV Pancreatic Cancer or Stage III or Stage IV Colon Cancer or Rectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Pancreatic Cancer|Psychosocial Effects of Cancer and Its Treatment
Interventions: OTHER: counseling intervention|OTHER: study of socioeconomic and demographic variables|PROCEDURE: psychosocial assessment and care|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effects of rTMS on Human Brain Activity
Status: WITHDRAWN
Conditions: Repetitive Transcranial Magnetic Stimulation (rTMS)
Interventions: DEVICE: rTMS|DEVICE: Sham rTMS|PROCEDURE: MRI scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Role of Leucine in the Regulation of Human Myofibrillar Protein Synthesis at Rest and Following Resistance Exercise
Status: COMPLETED
Conditions: Regulation of Muscle Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: whey protein|DIETARY_SUPPLEMENT: whey protein supplemented with leucine|DIETARY_SUPPLEMENT: whey protein supplemented with essential amino acids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Stellate Ganglion Block as Post-traumatic Stress Disorder (PTSD) Therapy: A Pilot Study
Status: UNKNOWN
Conditions: Stress Disorders, Post-Traumatic
Interventions: PROCEDURE: Stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Telitacicept Followed With Rituximab Therapy on APS Secondary to SLE
Status: RECRUITING
Conditions: Antiphospholipid Syndrome
Interventions: DRUG: Telitacicept|DRUG: Rituximab|DRUG: Aspirin|DRUG: Warfarin|DRUG: Hydroxychloroquine|DRUG: Prednisone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Matched Unrelated Donor Transplant for Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: PROCEDURE: NST using MUD for metastatic renal cell carcinoma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Prognostic Role of Lymph Node Dissection In Men With Prostate Cancer Treated With Radical Prostatectomy
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: PROCEDURE: Pelvic lymph node dissection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Solid Tumor
Interventions: DRUG: Technetium [99mTc]-H7ND injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Autologous Transplant Followed by Allogeneic Transplant for High Risk Neuroblastoma
Status: TERMINATED
Conditions: Neuroblastoma
Interventions: PROCEDURE: Related donor transplant|PROCEDURE: Cord blood transplant|DRUG: Busulfan|DRUG: Thymoglobulin|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Hyaluronic Acid Affect Periodontal Treatment?
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Scaling and root planning|DRUG: Hyaluronic acid gel (HA) and SRP|DRUG: HA mouthrinse and SRP|DRUG: HA mouthrinse+gel and SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Memory-enriched CAR-T Cells Immunotherapy for B Cell Lymphoma
Status: UNKNOWN
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Stage III Adult Diffuse Large Cell Lymphoma|Stage III Follicular Lymphoma|Stage III Mantle Cell Lymphoma|Stage IV Adult Diffuse Large Cell Lymphoma|Stage IV Follicular Lymphoma|Stage IV Mantle Cell Lymphoma
Interventions: DRUG: CD19.CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)
Status: COMPLETED
Conditions: Aging
Interventions: OTHER: Computerized Plasticity-Based Adaptive Cognitive Training|OTHER: Educational DVDs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium in Coronaries (MAGIC)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Infarction|Myocardial Ischemia
Interventions: DRUG: magnesium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: The Effect of a Community-based LAT-treated Management Model on the Violence Risk of Patients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: OTHER: LAT-treated Community Model|OTHER: care as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing ESWT With PRP for Plantar Fasciitis in High Demand Cohort
Status: UNKNOWN
Conditions: Fasciitis, Plantar
Interventions: BIOLOGICAL: platelet rich plasma|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate and Delayed Effects of Kinesio Taping on the Neuromuscular Performance
Status: COMPLETED
Conditions: Neuromuscular Performance, Balance and Function
Interventions: OTHER: Functional elastic tape|OTHER: placebo Functional elastic tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Internet-delivered Intervention for Parents of Children With ADHD
Status: ACTIVE_NOT_RECRUITING
Conditions: ADHD
Interventions: BEHAVIORAL: ADHDCoach|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Status: RECRUITING
Conditions: Atrial Fibrillation|Stroke|Stroke, Cardiovascular|Vascular Cognitive Impairment|Strokes Thrombotic|Stroke, Ischemic
Interventions: DEVICE: Cardiac and Brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Role of HIF-2a in the Pathogenesis of Reflux Esophagitis
Status: COMPLETED
Conditions: Esophagitis|Reflux Esophagitis|Gastroesophageal Reflux Disease
Interventions: OTHER: Cessation of Acid Suppressing Medications
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan
Status: COMPLETED
Conditions: Small Fiber Neuropathy|Fabry Disease|Ehlers Danlos Syndrome|Mitochondrial Disease
Interventions: DEVICE: Sudoscan|PROCEDURE: Skin biopsy|PROCEDURE: QSART
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery
Status: COMPLETED
Conditions: Post Operative Surgical Site Infection
Interventions: PROCEDURE: Supplemental Perioperative Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Real-world Therapy of ALK-positive NSCLC in Sweden: the Sequencing of ALK Tyrosine Kinase Inhibitor Drugs and Their Therapeutic Outcomes Based on Data From National Registers.
Status: COMPLETED
Conditions: ALK-positive NSCLC
Interventions: DRUG: crizotinib|DRUG: alectinib|DRUG: brigatinib|DRUG: ceritinib|DRUG: lorlatinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Intrinsic Focus on Gait Cycle and the Possible Confounding Effect of Noise in Patients With Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: OTHER: Baseline|OTHER: Intrinsic focus|OTHER: White noise|OTHER: environmental sound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Phase I/II Study of Decitabine and Valproic Acid in Relapsed/Refractory Leukemia or Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Leukemia|Myelodysplastic Syndromes
Interventions: DRUG: Decitabine|DRUG: Valproic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Use of PEG-rhG-CSF in Medium-high Risk of FN in Chemotherapy of Breast Cancer
Status: UNKNOWN
Conditions: Febrile Neutropenia
Interventions: DRUG: PEGCSF first level prophylactic use|DRUG: PEGCSF second level prophylactic use
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic and Appetite Responses to Altered Timing of Whey Protein Ingestion
Status: COMPLETED
Conditions: Obesity, Abdominal
Interventions: DIETARY_SUPPLEMENT: Whey Protein|OTHER: Mixed Macronutrient Breakfast Meal|OTHER: Mixed Macronutrient Lunch Meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Melatonin for Pediatric Emergence Agitation
Status: COMPLETED
Conditions: Emergence Agitation
Interventions: DRUG: Melatonin 5 MG/15 ML Oral Solution 0.05 mg/kg|DRUG: Melatonin 5 MG/15 ML Oral Solution 0.2mg/kg|DRUG: Melatonin 5 MG/15 ML Oral Solution 0.4mg/kg|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Type 2 Diabetes and the Brain in Adolescents
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Obesity|Pediatric Obesity|Insulin Resistance|Dysglycemia|Hyperglycemia
Interventions: PROCEDURE: Hyperglycemic clamp|PROCEDURE: Hyperinsulinemic Euglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study of S6G5T3 in the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: S6G5T-3|DRUG: S6G5T-8
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Simultaneous Pancreas-kidney Transplantation With Campath Protocol
Status: COMPLETED
Conditions: Pancreas-Kidney Transplantation
Interventions: DRUG: Alemtuzumab|DRUG: Rabbit Anti-Human Thymocyte Globulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients
Status: UNKNOWN
Conditions: Wound Infection
Interventions: DRUG: E. coli Phages cocktail|DRUG: Standard of care : Silver Sulfadiazine|DRUG: P. Aeruginosa, Phages cocktail
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Health Application (PACT) to Improve Engagement in Advance Care Planning
Status: NOT_YET_RECRUITING
Conditions: Malignant Solid Neoplasm
Interventions: OTHER: Internet-Based Intervention|OTHER: Best Practice|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Mirazid for Schistosomiasis Treatment
Status: COMPLETED
Conditions: Schistosoma Hematobium Infection|Schistosomiasis Mansoni
Interventions: DRUG: Myrrh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pyrotinib Combined With Trastuzumab Plus Aromatase Inhibitor in Treatment of Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Female|HER2-positive Breast Cancer|Hormone Receptor Positive Malignant Neoplasm of Breast|Metastatic Breast Cancer|Breast Diseases|Hormone Receptor Positive Tumor
Interventions: DRUG: Pyrotinib|DRUG: Trastuzumab|DRUG: Aromatase Inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia
Status: COMPLETED
Conditions: Frontotemporal Dementia (FTD)
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability Study of Bicalutamide 50 mg Tablet and Casodex Following a 50 mg Dose in Healthy Subjects Under Fed Conditions
Status: COMPLETED
Conditions: Prostate Cancer|Hirsutism
Interventions: DRUG: Bicalutamide 50 mg Film-Coated Tablets (Sandoz Inc., USA)|DRUG: Bicalutamide 50 mg Film-Coated Tablets (Casodex) (Astrazeneca Pharmaceutical LP, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SCI-Pex Study - Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids
Status: RECRUITING
Conditions: Hemorrhoids|Hemorrhoids, Internal|Suture; Complications, Infection or Inflammation|Rectal Diseases|Gastrointestinal Diseases
Interventions: DEVICE: PexyEazy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MEtoclopramide, DExamethasone or Axoli to Prevent or Delay Chemotherapy-induced Nausea and Vomiting in Moderately Emetogenic Non-AC-based Chemotherapy
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: metoclopramide|DRUG: dexamethason|DRUG: palonosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the 1-year Prognosis of Patients Under Veno-arterial Extracorporeal Membrane Oxygenation for Cardiogenic Shock With Blood Transfusion Requirement
Status: NOT_YET_RECRUITING
Conditions: Extracorporeal Membrane Oxygenation Complication|Blood Cells Transfusion|Transfusion Related Complication
Interventions: OTHER: Transfusion rate of red blood cells
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study of Efficacy and Tolerability of Levetiracetam Monotherapy in Subjects With Childhood Absence Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Childhood Absence Epilepsy|Seizures
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Elevating Voices, Addressing Depression, Toxic Stress and Equity in Group Prenatal Care
Status: ENROLLING_BY_INVITATION
Conditions: Pregnancy Related|Perinatal Depression
Interventions: BEHAVIORAL: EleVATE Group Care|BEHAVIORAL: Individual Prenatal Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children
Status: COMPLETED
Conditions: Hyperhomocysteinemia|Obesity
Interventions: DRUG: Folic Acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparisons of Clinical Outcomes Between Novel Tailored Transvaginal Mesh Surgery and Vaginal Native Tissue Repair Surgery for Pelvic Organ Prolapse
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: Pelvic organ prolapse surgery without mesh|PROCEDURE: Pelvic organ prolapse surgery with mesh
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Antiremodeling Effect Of Aldosterone Receptors Blockade With Canrenone In Mild Chronic Heart Failure. AREA IN-CHF Study
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Canrenone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: DIAGNOSTIC
Clinical trial: Group Study To Investigate The Safety, Toleration And Pharmacokinetics Of Multiple Oral Doses Of PF-04531083 In Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: PF-04531083 or Placebo|DRUG: PF-04531083 or Placebo|DRUG: PF-04531083 or Placebo|DRUG: PF-04531083 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of GIP(3-30)NH2
Status: COMPLETED
Conditions: Endocrine - Other
Interventions: OTHER: GIP receptor antagonist|OTHER: GIP receptor agonist|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tenofovir Monotherapy in Patients With Chronic Hepatitis B Patients Who Had Achieved Complete Viral Suppression on Entecavir Plus Tenofovir
Status: UNKNOWN
Conditions: Proportion of Patients With a Sustained Virological Response (Serum HBV DNA <20 IU/mL) at Week 48
Interventions: DRUG: tenofovir monotherapy|DRUG: tenofovir plus entecavir combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Appliance in Obstructive Sleep Apnea. A Randomized Controlled Blinded Multicenter Study Comparing Two Devices
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: Monobloc|DEVICE: Bibloc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Black Rice Bran Extract on Immune Enhancement
Status: UNKNOWN
Conditions: Immunity
Interventions: DIETARY_SUPPLEMENT: Black rice bran extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Erlotinib Concurrent With Radiation Therapy in Non-small-cell Lung Cancer
Status: UNKNOWN
Conditions: Carcinoma, Non-Small Cell Lung
Interventions: OTHER: Radiation Therapy and EGFR-TKI target therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nasal Antisepsis for C. Auris Prevention
Status: RECRUITING
Conditions: Candida Auris Infection|Colonization, Asymptomatic
Interventions: DRUG: Povidone Iodine Topical
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: BEHAVIORAL: Prolonged Exposure (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatocellular Cancer|Metastatic Pancreatic Cancer|Metastatic Colorectal Cancer|Liver Metastasis
Interventions: DRUG: nivolumab|DRUG: tadalafil|DRUG: oral vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Shear-wave Elastography-guided Aspiration and Biopsy for Diagnosis in Lung Tumor
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Tumor
Interventions: PROCEDURE: different types of ultrasound technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Immunogenicity of Novel Oral Poliovirus Vaccine Type 2 (nOPV2), bOPV and IPV
Status: NOT_YET_RECRUITING
Conditions: Polio
Interventions: BIOLOGICAL: polio vaccines: nOPV2, bOPV, IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC
Status: RECRUITING
Conditions: NSCLC
Interventions: DRUG: EIK1001|DRUG: Pembrolizumab|DRUG: Paclitaxel|DRUG: Pemetrexed|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Irreversible Electroporation(IRE) For Uterine Cervical Neoplasms
Status: COMPLETED
Conditions: Uterine Cervical Neoplasms
Interventions: PROCEDURE: Irreversible electroporation (IRE)|DEVICE: NanoKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adrenaline for the Treatment of No-Reflow in Normotensive Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome|No-Reflow Phenomenon|Normotensive
Interventions: DRUG: Adrenaline|DRUG: Adenosine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testicular Injection of Autologous Stem Cells for Treatment of Patients With Azoospermia
Status: UNKNOWN
Conditions: Azoospermia
Interventions: BIOLOGICAL: Stem Cells|BIOLOGICAL: Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Effects of Zemplar Injection and Calcijex on Intestinal Absorption of Calcium
Status: COMPLETED
Conditions: Secondary Hyperparathyroidism|Chronic Kidney Disease
Interventions: DRUG: Zemplar|PROCEDURE: 42 Ca carbonate absorption via single tracer method|DRUG: Calcijex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Letrozole in Patients With Operable Hormone Receptor Positive, HER2 Negative Breast Cancer
Status: COMPLETED
Conditions: Breast Adenocarcinoma|Invasive Breast Carcinoma|Resectable Breast Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study on an Investigational Yellow Fever Vaccine Compared With YF-VAX in Adults in the USA
Status: ACTIVE_NOT_RECRUITING
Conditions: Yellow Fever (Healthy Volunteers)
Interventions: BIOLOGICAL: Yellow fever vaccine (produced on serum-free Vero cells)|BIOLOGICAL: Yellow fever vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Induction Treatment in SCC of the Head and Neck Region - Concomitant Chemotherapy and Low-dose Radiotherapy
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of Oral Cavity|Pharynx Carcinoma|Larynx Carcinoma|Paranasal Sinus Carcinoma
Interventions: OTHER: Chemotherapy (carboplatin+paclitaxel) with concomitant low dose ionizing radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases
Status: RECRUITING
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloid Leukemia|Juvenile Myelomonocytic Leukemia|Myelodysplastic Syndromes|Chronic Myeloid Leukemia|Lymphoma, Non-Hodgkin|Lymphoma, Hodgkin
Interventions: DEVICE: Miltenyi CliniMACS Prodigy ® system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reflexology's Effect on Polycystic Ovary Syndrome (PCOS)
Status: UNKNOWN
Conditions: Polycystic Ovary Syndrome
Interventions: OTHER: Reflexology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of a Manualized Wireless Moisture Pager Intervention for Teaching Toileting in Children With Autism
Status: COMPLETED
Conditions: Autism|Enuresis|Incontinence
Interventions: DEVICE: Wireless Moisture Pager (WMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Zinc Supplement as Adjunctive Therapy for Erosive Oral Lichen Planus
Status: COMPLETED
Conditions: Oral Lichen Planus
Interventions: DRUG: Oral zinc supplement|DRUG: triamcinolone acetonide Oral paste
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction
Status: NOT_YET_RECRUITING
Conditions: Myocardial Infarction|Thrombosis
Interventions: RADIATION: Hybrid 18F-GP1 positron emission tomography and coronary computed tomography coronary angiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients )
Status: COMPLETED
Conditions: Hepatitis E
Interventions: BIOLOGICAL: Recombinant Hepatitis E Vaccine (Escherichia Coli)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dose-ranging Efficacy and Pharmacokinetics Study of Intravenous Atorvastatin in Hypercholesterolemic Patients
Status: COMPLETED
Conditions: Hypercholesterolemia|Dyslipidemias
Interventions: DRUG: Atorvastatin injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Pain Management for Older Adults in the Emergency Department (ED)
Status: COMPLETED
Conditions: Abdominal Pain Care
Interventions: OTHER: ePCA and Pain keycept intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: fluorouracil|DRUG: irinotecan hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of HPV on a Cohort of Southern Italian Women: Epidemiological, Clinical, Morphological and Microbiological Features
Status: COMPLETED
Conditions: Cervix Cancer
Interventions: DIAGNOSTIC_TEST: Cervical biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
Status: RECRUITING
Conditions: Solid Tumors With HRAS Alterations|Non Small Cell Lung Cancer (NSCLC)|Colorectal Cancer (CRC)|Pancreatic Ductal Adenocarcinoma (PDAC)|Clear Cell Renal Cell Carcinoma (ccRCC)
Interventions: DRUG: KO-2806|DRUG: Cabozantinib|DRUG: Adagrasib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbohydrate Antigen 125-guided Therapy in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: CA125 guided strategy|DRUG: CA125 guided strategy|DRUG: CA125 guided strategy|OTHER: CA125 guided strategy|DRUG: Standard treatment strategy|DRUG: CA125 guided strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Role of Psychiatric Profile in Prehabituated Patients After Vestibular Schwannoma Surgery
Status: COMPLETED
Conditions: Vestibular Schwannoma|Vestibular Function Disorder
Interventions: PROCEDURE: intratympanic application of gentamicin|PROCEDURE: microsurgical removal of vestibular schwannoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Double Blind, Multicenter Study of the Safety and Efficacy of Valdecoxib 40 mg Once Daily Compared With Diclofenac 75 mg Twice Daily in Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: valdecoxib|DRUG: diclofenac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEDEX Hidden Valley 2008
Status: COMPLETED
Conditions: Hypoxia
Interventions: DIETARY_SUPPLEMENT: Carbohydrate energy drink|DIETARY_SUPPLEMENT: Aspartame
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Compare the Efficacy and Safety of Raltegravir Versus Efavirenz Combination Therapy in Treatment-naïve HIV-1 Patients
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: DRUG: Raltegravir|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 3 Trial Comparing TACE and TARE in Unilobar Advanced Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: transarterial radioembolization (TARE)|PROCEDURE: transarterial chemoembolization (TACE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study of Hetrombopag in Severe Aplastic Anemia
Status: RECRUITING
Conditions: Treatment-naive Severe Aplastic Anemia
Interventions: DRUG: Hetrombopag Olamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab and Ramucirumab in Pts With Progressive TCC After Treatment With an Immune Checkpoint Inhibitor
Status: WITHDRAWN
Conditions: Transitional Cell Carcinoma
Interventions: DRUG: Pembrolizumab and Ramucirumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Test lens|DEVICE: Control lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Fecal Microbiota Transplantation and Steroid Therapy in Patients With Severe Alcoholic Hepatitis.
Status: UNKNOWN
Conditions: Severe Alcoholic Hepatitis
Interventions: OTHER: Fecal Microbiota Transplantation|DRUG: Steroids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Closed-loop Control of Glucose Levels (Artificial Pancreas) During Exercise in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: OTHER: 60-minute exercise|OTHER: 40-minute interval exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing the Approach of Mobile Application Use to Improve Medication Adherence in Patients With Hypertension
Status: COMPLETED
Conditions: Medication Adherence|Hypertension
Interventions: OTHER: Mobile application (BP-n-Me)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: E7 TCR T Cells for Human Papillomavirus-Associated Cancers
Status: RECRUITING
Conditions: Papillomavirus Infections|Cervical Intraepithelial Neoplasia|Carcinoma In Situ|Vulvar Neoplasms|Vulvar Diseases
Interventions: BIOLOGICAL: E7 TCR cells|DRUG: Aldesleukin|DRUG: Fludarabine|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Platelet-Inhibitor Drug Trial in Coronary Angioplasty
Status: COMPLETED
Conditions: Angina Pectoris|Cardiovascular Diseases|Coronary Disease|Heart Diseases|Myocardial Ischemia
Interventions: DRUG: aspirin|DRUG: dipyridamole|PROCEDURE: angioplasty, transluminal, percutaneous coronary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Optimisation of Anticoagulation in Patients on Nocturnal Hemodialysis
Status: COMPLETED
Conditions: Hemodialysis|Coagulation
Interventions: OTHER: Anticoagulation strategy|OTHER: Blood sampling|OTHER: Scanning of hemodialyzer with micro-computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT