pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: The Effect of Topical Brimonidine on the Ocular Hemodynamics in Patients of POAG Using OCTA
Status: COMPLETED
Conditions: Glaucoma, Primary Open Angle|Ocular Blood Flow|Optical Coherence Tomography Angiography
Interventions: DRUG: Brimonidine tartrate 0.2% ophthalmic solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study
Status: COMPLETED
Conditions: Respiratory Failure
Interventions: DEVICE: Video Laryngoscopy|DEVICE: Apneic Oxygenation|DEVICE: Direct Laryngoscopy|DEVICE: No Apneic Oxygenation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
Status: ACTIVE_NOT_RECRUITING
Conditions: Weight Loss|Blood Pressure|Lipid Disorder|PreDiabetes|Diabete Mellitus
Interventions: BEHAVIORAL: Low-fat plant-based diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
Status: RECRUITING
Conditions: Urologic Chronic Pelvic Pain Syndrome (UCPPS)|Interstitial Cystitis|Bladder Pain Syndrome|Chronic Prostatitis|Chronic Pain|Chronic Pelvic Pain Syndrome|Chronic Overlapping Pain Disorders
Interventions: BEHAVIORAL: Minimal Contact-Cognitive Behavior Therapy|BEHAVIORAL: Patient Education/Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study to Assess the Impact of a Mobile Health Application (App) on Clinical Outcomes and Satisfaction of Older HIV-Infected Patients, as an Emerging Tool for Care, Education and Prevention.
Status: COMPLETED
Conditions: HIV-1 Infection
Interventions: OTHER: Mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia
Status: COMPLETED
Conditions: COVID-19 Pneumonia
Interventions: DRUG: MSTT1041A|DRUG: MSTT1041A-matched Placebo|DRUG: UTTR1147A|DRUG: UTTR1147A-matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of JZP150 in Adults With Posttraumatic Stress Disorder
Status: COMPLETED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: JZP150|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Zinc and Vitamin A Supplementation on Diarrhea, Physical Growth and Immune Response in Malnourished Children
Status: COMPLETED
Conditions: Diarrhea|Pneumonia|Acute Respiratory Tract Infection
Interventions: DRUG: Zinc and vitamin A single dose at enrollment|DRUG: Placebo and vitamin A single dose at enrollment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alogliptin Tablets Special Drug Use Surveillance "Type 2 Diabetes Mellitus: Monotherapy/Combination Therapy With α-GI"
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus Who Have Been Examined at a Medical Institution
Interventions: DRUG: Alogliptin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Ultrasound-guided Erector Spinae Block and Intraoperative Intercostal Nerve Block on Postoperative Analgesia in Thoracic Surgery
Status: COMPLETED
Conditions: Anesthesia|Postoperative Pain|Ultrasound Therapy; Complications
Interventions: PROCEDURE: Intrathoracic Intercostal Nerve Block|PROCEDURE: Erector Spinae Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Continuous Alloreactive T Cell Depletion and Regulatory T Cell Expansion for the Treatment of Steroid-refractory or Dependent Chronic GVHD
Status: UNKNOWN
Conditions: Chronic GVHD After HCT for Cancer or Immune Disease
Interventions: OTHER: Autologous peripheral blood mononuclear cells ex vivo depleted for reactive T cells, using TH9402 based photodynamic therapy, in a final formulation of 10% DMSO, 30% autologous plasma in PlasmaLyte.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study in Pregnant Women With Chronic Inflammatory Diseases Treated With Cimzia (Certolizumab Pegol)
Status: COMPLETED
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Crohn's Disease|Axial Spondyloarthritis|Plaque Psoriasis
Interventions: DRUG: Pharmacokinetics of certolizumab pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Omr-IgG-am(Trademark) for Treating Patients With or at High Risk for West Nile Virus Disease
Status: COMPLETED
Conditions: West Nile Virus
Interventions: DRUG: Omr-IgG-am
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer.
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Interventions: RADIATION: SMART|DRUG: DDP|DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Resilience-based Intervention on Emotional Regulation, Grit and Life Satisfaction: A Comparative Study Between Egyptian and Saudi Nursing Students
Status: UNKNOWN
Conditions: Resilience-based Intervention, Emotional Regulation, Grit and Life Satisfaction
Interventions: BEHAVIORAL: Resilience-based intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Impact of ESP on Neurophysiological Monitoring in Scoliotic Patients
Status: RECRUITING
Conditions: Neurophysiological Monitoring Under TIVA
Interventions: PROCEDURE: erector spinae block (ESP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Internet-based CBIT for Children With Chronic Tics
Status: UNKNOWN
Conditions: Tourette Syndrome in Children|Tourette Syndrome in Adolescence|Chronic Tic Disorder
Interventions: BEHAVIORAL: ICBIT|BEHAVIORAL: waiting list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Study of the Efficacy of a New Intervention for Medication Adherence in Chronic Illness: Medications, Meaning and Me (The 3-M Study)
Status: COMPLETED
Conditions: Self-management in Heart Failure
Interventions: BEHAVIORAL: CHIME 3-M|BEHAVIORAL: attention control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Treatment of Cryptosporidiosis
Status: COMPLETED
Conditions: Cryptosporidiosis
Interventions: OTHER: Nitazoxanide with Lactobacillus Reuteri DSM 17938|OTHER: Nitazoxanide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Use of Pharmacogenetics to Select Erbitux or Cisplatin to Treat Head and Neck Cancer
Status: TERMINATED
Conditions: Head and Neck Squamous Cell Cancer
Interventions: DRUG: Cisplatin|DRUG: cetuximab|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19
Status: COMPLETED
Conditions: Robotic Exoskeleton|Post-acute Covid-19 Syndrome|Rehabilitation Outcome|Physical And Rehabilitation Medicine
Interventions: DEVICE: Training with a Robotic Hand Exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cilengitide in Recurrent and/or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Status: COMPLETED
Conditions: Squamous Cell Cancer
Interventions: DRUG: Cilengitide 2000 mg once weekly|DRUG: Cilengitide 2000 mg twice weekly|DRUG: Cetuximab|DRUG: 5-fluorouracil (5-FU)|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Evaluate the Efficacy and Safety of YMC026 in Respiratory Disease Patients
Status: COMPLETED
Conditions: Respiratory Disease
Interventions: DRUG: YMC026|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-Invasive Method for Evaluation of Cardiac Resynchronization Therapy
Status: RECRUITING
Conditions: Heart Failure|Pacemaker DDD|Cardiomyopathies|Heart Diseases|Cardiovascular Diseases
Interventions: DEVICE: Cardiac Resynchronization Therapy (CRT)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ridge Preservation Using Different Techniques
Status: ENROLLING_BY_INVITATION
Conditions: Alveolar Ridge Augmentation|Connective Tissue|Tooth Extraction|Membranes; Retained
Interventions: PROCEDURE: Alveolar ridge preservation|PROCEDURE: Alveolar ridge preservation|PROCEDURE: Alveolar ridge preservation|PROCEDURE: Alveolar ridge preservation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Upper Extremity Plyometric Exercises on Proprioception, Time to Peak Torque and Performance in Young Female Basketball Players
Status: COMPLETED
Conditions: Plyometric Exercise|Proprioception|Upper Quarter y Balance Test|The Closed Kinetic Chain Upper Extremity Stability Test
Interventions: OTHER: Plyometric Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Introduction Study of Dual HIV & Syphilis Rapid Diagnostic Tests in Antenatal Clinics in Colombia
Status: COMPLETED
Conditions: Syphilis|HIV
Interventions: DEVICE: Single HIV RDT and single syphilis RDT|DEVICE: Dual HIV/syphilis RDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Pegylated Interferon on Liver Fibrosis in Co-infected Patient With HIV and Hepatitis C
Status: COMPLETED
Conditions: HIV Infections|Hepatitis C, Chronic
Interventions: BIOLOGICAL: Peginterferon alpha-2a (Pegasys®)|DRUG: Ribavirin|DRUG: HIV antiretroviral therapy|DRUG: HIV antiretroviral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Arbaclofen for the Treatment of Social Withdrawal in Subjects With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism Spectrum Disorders
Interventions: DRUG: Arbaclofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: WOUNDCHEK™ Protease Status Point of Care (POC) Diagnostic Test on DFU
Status: UNKNOWN
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: PROMOGRAN|DEVICE: Tielle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Super-Selective Intraarterial Cerebral Infusion Of Temozolomide (Temodar) For Treatment Of Newly Diagnosed GBM And AA
Status: COMPLETED
Conditions: Glioblastoma Multiforme|Anaplastic Astrocytoma
Interventions: DRUG: Super-Selective Intraarterial Intracranial Infusion of Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Intrathecal and Intravenous Analgesia in Patients Undergoing Liver Resection
Status: UNKNOWN
Conditions: Liver Diseases|Liver Cancer|Liver Metastases
Interventions: PROCEDURE: Intravenous morphine|PROCEDURE: Intrathecal morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance
Status: RECRUITING
Conditions: Healthy Active Athletes
Interventions: DEVICE: Hyperbaric Oxygen Therapy - HBOT|DEVICE: Intermittent Hypoxic Training - IHT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Levels in Stage IV Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: vitamin D repletion with Cholecalciferol (vitamin D3 50,000 International Units)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Randomized Trial
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sourdough Bakery Products and Digestive Function
Status: COMPLETED
Conditions: Dyspepsia
Interventions: DIETARY_SUPPLEMENT: Sourdough --> Brewer's Yeast|DIETARY_SUPPLEMENT: Brewer's Yeast --> Sourdough
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of ABBV-383 Assessing Adverse Events and Clinical Activity With Subcutaneous (SC) Injection in Adult Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Subcutaneous (SC) ABBV-383|DRUG: Intravenous (IV) ABBV-383
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Chewing Gum on Postoperative Bowel Activity and Postoperative Pain After Total Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: PROCEDURE: chewing gum Group|PROCEDURE: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clinical Trial of Wrist Ambulatory Blood Pressure Monitor in Conformance With the EN ISO 81060-2:2018+AMD1:2020
Status: COMPLETED
Conditions: Blood Pressure
Interventions: DEVICE: Wrist Ambulatory Blood Pressure Monitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Survival and Prognostic Factors of Squamous Cell Carcinoma of the Nasal Vestibule
Status: RECRUITING
Conditions: Nasal Vestibule Carcinoma|Rhinectomy|Nasal Vestibule|Squamous Cell Carcinoma
Interventions: PROCEDURE: Rhinectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Schizo Affective Disorder
Interventions: DRUG: Lumateperone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ethnic on Moxifloxacin Induced QT Interval Prolongation in Korean and Japanese Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Moxifloxacin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of Talimogene Laherparepvec in Stage IIIc and Stage IV Malignant Melanoma
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-use Digital Flexible Ureteroscope vs Nondisposable Fiber Optic vs Digital Ureteroscope
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: PROCEDURE: single use digital ureteroscope|PROCEDURE: reusable fiberoptic ureteroscope|PROCEDURE: reusable digital flexible ureteroscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postmarketing Surveillance Study of Berotec® N 100 µg Metered-dose Inhaler in Chronic Obstructive Respiratory Tract Disease
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Berotec® N 100 µg Metered-dose Inhaler
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Japanese Study of Ipilimumab Administered in Combination With Paclitaxel/Carboplatin in Patients With Nonsmall-cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Ipilimumab, 3 mg|DRUG: Ipilimumab, 10 mg|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAP-001 in Gout Patients
Status: COMPLETED
Conditions: Gout|Hyperuricemia
Interventions: DRUG: SAP-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
Status: COMPLETED
Conditions: Ulcer
Interventions: DRUG: Ibuprofen/famotidine|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Risk of Pneumothorax With and Without Chest Tube Clamping in Patients With Pleural Pathology
Status: COMPLETED
Conditions: Pneumothorax|Chest Tube|Pleural Diseases
Interventions: PROCEDURE: Clamping|PROCEDURE: Non Clampling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Supplementation and Tibia Fracture. Does it Improve Healing Rate?
Status: UNKNOWN
Conditions: Tibial Fractures|Vitamin D Deficiency|Fracture Healing
Interventions: DIETARY_SUPPLEMENT: Vitamin D3.|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases
Status: RECRUITING
Conditions: Anatomic Stage IV Breast Cancer AJCC v8|Invasive Breast Carcinoma|Metastatic HER2 Negative Breast Carcinoma|Metastatic Malignant Neoplasm in the Brain|Prognostic Stage IV Breast Cancer AJCC v8
Interventions: BIOLOGICAL: Sacituzumab Govitecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma
Status: RECRUITING
Conditions: Melanoma
Interventions: DRUG: fianlimab|DRUG: cemiplimab|DRUG: relatlimab+nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart to Heart: Testing a Sexual Health Training for Foster and Kinship Caregivers
Status: COMPLETED
Conditions: Sexual Behavior|Conflict, Family|Pregnancy Related|Sexually Transmitted Diseases|Family and Household
Interventions: BEHAVIORAL: Heart to Heart Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact VR: An Emotion Recognition and Regulation Training Program for Youth With CD
Status: RECRUITING
Conditions: Conduct Disorder|Conduct Disorders in Children|Conduct Disorders in Adolescence|Callous-Unemotional Traits
Interventions: BEHAVIORAL: Virtual Reality|OTHER: Comparative Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of AZX100 Drug Product Following Excision of Keloid Scars
Status: COMPLETED
Conditions: Scar Prevention|Scar Reduction
Interventions: DRUG: AZX100 Drug Product|DRUG: AZX100 Drug Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Rollover Study of BI 201335 in Combination With Pegylated Interferon-alpha and Ribavirin in Treatment-experienced Genotype 1 Hepatitis C Infected Patients
Status: COMPLETED
Conditions: Hepatitis C
Interventions: DRUG: BI 201335|DRUG: PegIFN/RBV
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Epidural Decompression Surgery Within 24 Hours After Acute Spinal Cord Injury Improves Spinal Nerve Function
Status: UNKNOWN
Conditions: Spinal Cord Injuries
Interventions: PROCEDURE: early epidural decompression group|PROCEDURE: delayed epidural decompression group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sí Texas Hope Family Health Center
Status: COMPLETED
Conditions: Chronic Disease|Hypertension|Diabetes|Hypercholesterolemia|Depression|Obesity
Interventions: BEHAVIORAL: Enhanced Integrated Behavioral Health Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Classic High-frequency rTMS Treatment Versus a Deep rTMS Treatment
Status: RECRUITING
Conditions: Depressive Disorder, Treatment-Resistant
Interventions: DEVICE: classic rTMS using the 8-shaped coil|DEVICE: deep rTMS using the H1-shaped coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Experimental Gene Transfer Procedure to Treat Alpha 1-Antitrypsin Deficiency
Status: COMPLETED
Conditions: Alpha 1-Antitrypsin Deficiency
Interventions: GENETIC: rAAV2-CB-hAAT Gene Vector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Vascular Impairment in Chronic Obstructive Pulmonary Disease (COPD) Assessed by MRI
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DIAGNOSTIC_TEST: chest Magnetic Resonance Imaging (MRI) using Gadolinium-based contrast agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD
Status: COMPLETED
Conditions: Laryngospasm|Hypoxemia
Interventions: OTHER: Prophylactic suctioning when clinically indicated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lung Cancer Screening Eligibility Assessment
Status: ACTIVE_NOT_RECRUITING
Conditions: Lung Cancer
Interventions: BEHAVIORAL: Framed Introductory Message A|BEHAVIORAL: Framed Introductory Message B|BEHAVIORAL: Framed Introductory Message C|BEHAVIORAL: Framed Tobacco Use Message A|BEHAVIORAL: Framed Tobacco Use Message B|BEHAVIORAL: Financial Incentive
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Three-Arm Study of the Safety and Efficacy of Pirfenidone in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Low-Level Laser Stimulation on Hearing Thresholds
Status: TERMINATED
Conditions: Hearing Loss
Interventions: RADIATION: Low-level Laser Therapy|OTHER: Placebo Comparator: Disabled Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy Comparison Between Different Management Strategies for Consistent OAB in Patients With SVMs After Surgery
Status: UNKNOWN
Conditions: Spinal Vascular Disorder Nos|Overactive Bladder
Interventions: PROCEDURE: surgery|PROCEDURE: sacral neuromodulation|PROCEDURE: botulinum toxin A injection|DRUG: M receptor antagonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adaptive Goals and Interventions for Lifestyle Enhancement
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: Core|BEHAVIORAL: Standard Diet Monitoring|BEHAVIORAL: Simplified Diet Monitoring|BEHAVIORAL: Adaptive Activity Goals (Daily)|BEHAVIORAL: Adaptive Activity Goals (Weekly)|BEHAVIORAL: Message Decision Points (Fixed)|BEHAVIORAL: Message Decision Points (Adaptive)|BEHAVIORAL: Message Decision Rules (Standard)|BEHAVIORAL: Message Decision Rules (Adaptive)|BEHAVIORAL: Message Choice (No)|BEHAVIORAL: Message Choice (Yes)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: FMT for MDRO Colonization After Infection in Renal Transplant Recipients
Status: TERMINATED
Conditions: Infection Due to Resistant Organism
Interventions: BIOLOGICAL: Fecal Microbiota Transplant (FMT)|PROCEDURE: Bowel preparation|PROCEDURE: Stool or perirectal swab sampling|OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Language Disorders and Interactions Between Mnesic Capabilities and Semantic Competencies in Patients With Psychosis
Status: RECRUITING
Conditions: Psychosis|Schizophrenia|At-risk Mental State|Language Disorders
Interventions: BEHAVIORAL: Language assessment|BEHAVIORAL: TLC - Scale for the Assessment of Thought, Language, and Communication|BEHAVIORAL: MINI - Mini International Neuropsychiatric Interview|COMBINATION_PRODUCT: CAST - Cannabis Abuse Screening Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Safety and Efficacy of KDR2-2 Suspension Eye Drops in the Treatment of Corneal Neovascularization
Status: UNKNOWN
Conditions: Corneal Neovascularization
Interventions: DRUG: KDR2-2 suspension eye drops
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of KAI-1678 to Treat Pain in Subjects With Postherpetic Neuralgia
Status: COMPLETED
Conditions: Postherpetic Neuralgia
Interventions: DRUG: Placebo|DRUG: KAI-1678|DRUG: Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Coping and Adjusting to Living With Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: CBT for Uncertainty Tolerance|BEHAVIORAL: Traditional CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and Skin Structure Infection
Status: COMPLETED
Conditions: Skin Diseases, Bacterial
Interventions: DRUG: Oritavancin|DRUG: Placebo (D5W)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Intranasal Oxytocin and Social Cognition, Implicit Preferences and Craving in Alcohol Drinkers
Status: COMPLETED
Conditions: AOD Use, Abuse, and Dependence
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Precision Rifampin Trial for Personalized Dosing
Status: NOT_YET_RECRUITING
Conditions: Tuberculosis
Interventions: DIAGNOSTIC_TEST: urine spectrophotometry for rifampin absorbance
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Performance of MTA Cavity Lining in the Treatment of Deep Caries Lesions
Status: UNKNOWN
Conditions: Mineral Trioxide Aggregate|Calcium Hydroxide|Indirect Pulp Capping
Interventions: DEVICE: MTA|DEVICE: Dycal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
Status: COMPLETED
Conditions: Trauma|Flail Chest|Rib Fractures|Surgery
Interventions: DRUG: NSAID|DRUG: Opioids|DRUG: Thoracic Epidural anaesthesia|DRUG: Paracetamol|PROCEDURE: Surgical management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atrial Fibrillation Detecting Software Gung Atrial Fibrillation Detecting Software
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: Chang Gung Atrial Fibrillation Detecting Software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Chilled Needle on the Development of Pain and Ecchymosis in Subcutaneous Injection in Adults
Status: RECRUITING
Conditions: Pain|Ecchymosis|A Randomized Controlled Trial|Subcutaneous Injections
Interventions: OTHER: Chilled Needle|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a New Diagnostic Test on the Care of Prostate Cancer Patients: The ProMark™ Clinical Utility Study
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: OTHER: ProMark Information and Test Results
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Dietary Intervention in Follicular Lymphoma
Status: UNKNOWN
Conditions: Follicular Lymphoma
Interventions: DRUG: Omega 3 fatty acids (EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid))|DRUG: Selenium (L-Selenomethionine),|DRUG: Garlic extract (Allicin)|DRUG: Pomegranate juice (ellagic acid)|DRUG: Grape juice (resveratrol, quercetin)|DRUG: Green Tea (Epigallocathechin gallate)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Risk Factors for Neuroendocrine Neoplasms
Status: NOT_YET_RECRUITING
Conditions: Neuroendocrine Neoplasm of Lung|Neuroendocrine Neoplasm of Gastrointestinal Tract (Disorder)
Interventions: OTHER: Case-control study (no intervention)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect Of Reflexology On Pain, Anxiety And Comfort Level
Status: ACTIVE_NOT_RECRUITING
Conditions: Myocardial Infarction|Angina Pectoris
Interventions: OTHER: reflexology massage|OTHER: Placebo massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Local Anesthetic Infiltration VS Trasversalis Fascia Block VS Spinal Anesthesia
Status: UNKNOWN
Conditions: Inguinal Hernia
Interventions: PROCEDURE: Blind Local Anesthetic infiltration|PROCEDURE: Transversals Fascia Block|PROCEDURE: Spinal Anesthesia|DRUG: Ropivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Prevalence of Olfactory Disorders in Systemic Scleroderma
Status: TERMINATED
Conditions: Olfactory Disorders|Scleroderma
Interventions: DIAGNOSTIC_TEST: olfactory testing with specific odorants (localisation and identification)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Osteoarthritis, Knee|Arthritis, Rheumatoid|Intra-Articular Fractures|Joint Instability|Genu Valgum or Varum
Interventions: DEVICE: UHMWPE with Vitamin E|DEVICE: UHMWPE without Vitamin E
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: NT-proBNP to Assess Trastuzumab-induced Cardiotoxicity
Status: RECRUITING
Conditions: Cardiotoxicity|Breast Cancer|Treatment Side Effects
Interventions: DIAGNOSTIC_TEST: Plasma NT-proBNP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission
Status: COMPLETED
Conditions: Malaria,Falciparum
Interventions: DRUG: Pyronaridine Tetraphosphate/Artesunate|DRUG: Dihydroartemisinin/Piperaquine|DRUG: Primaquine Diphosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Vaccine Therapy in Treating Patients With Melanoma of the Eye
Status: TERMINATED
Conditions: Intraocular Melanoma
Interventions: BIOLOGICAL: MART-1 antigen|BIOLOGICAL: NA17-A antigen|BIOLOGICAL: gp100 antigen|BIOLOGICAL: tyrosinase peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Combination Study of IPH2201 (Monalizumab) With Ibrutinib in Relapsed, Refractory or Previously Untreated CLL
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia
Interventions: DRUG: monalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pozelimab and Cemdisiran Combination Treatment in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Have Received Pozelimab Monotherapy
Status: COMPLETED
Conditions: Paroxysmal Nocturnal Hemoglobinuria
Interventions: DRUG: Pozelimab|DRUG: Cemdisiran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Application of Continuous Positive Airway Pressure in Coronavirus Patients at Risk of Obstructive Sleep Apnea
Status: COMPLETED
Conditions: Covid19|Obstructive Sleep Apnea|CPAP Ventilation|Corona Virus Infection
Interventions: DEVICE: CPAP ( Continuous positive airway pressure)|DEVICE: oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study on Olaparib Plus Abiraterone as First-line Therapy in Men With Metastatic Castration-resistant Prostate Cancer (China Cohort)
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: olaparib|DRUG: abiraterone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early Point-Of-Care Blood Tests, ECG & X-rays in the Emergency Department
Status: COMPLETED
Conditions: Emergency Medicine|Point-of-Care Testing
Interventions: DIAGNOSTIC_TEST: iSTAT|DIAGNOSTIC_TEST: CBC|DIAGNOSTIC_TEST: ECG|DIAGNOSTIC_TEST: Lodox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy
Status: RECRUITING
Conditions: Smoking Cessation|Nicotine Dependence
Interventions: DRUG: NFL-101 dose 1|DRUG: NFL-101 dose 2|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dynamic Perfusion Computed Tomography in Patients With Localized Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Stage IA Non-Small Cell Lung Carcinoma|Stage IB Non-Small Cell Lung Carcinoma|Stage IIA Non-Small Cell Lung Carcinoma|Stage IIB Non-Small Cell Lung Carcinoma
Interventions: DEVICE: Computed Tomography Perfusion Imaging|OTHER: Laboratory Biomarker Analysis|RADIATION: Stereotactic Body Radiation Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Expanding Rural Access: Distance Delivery of Support Groups (Main Study)
Status: COMPLETED
Conditions: Depression|Breast Cancer|Stress|Breast Cancer Non-invasive Breast Cancer|Breast Cancer Early Stage Breast Cancer (Stage 1-3)|Breast Cancer Metastatic Breast Cancer
Interventions: BEHAVIORAL: Videoconferencing support group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Augmented Reality Applied Book Reading in the Preoperative Period
Status: NOT_YET_RECRUITING
Conditions: Preoperative Anxiety
Interventions: DEVICE: augmented reality book|DEVICE: book
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
Status: COMPLETED
Conditions: Infertility
Interventions: OTHER: Oocyte double chemical activation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Iron Overload in Patients Undergoing Donor Stem Cell Transplant
Status: COMPLETED
Conditions: Cancer|Hematopoietic Stem Cell Transplantation|Allogeneic Hematopoietic Cell Transplantation
Interventions: PROCEDURE: magnetic resonance imaging|PROCEDURE: Serum ferritin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Biological Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|DRUG: carboplatin|DRUG: cyclophosphamide|DRUG: thiotepa|PROCEDURE: peripheral blood stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Risk of Asymptomatic Cerebral Embolism During AF Ablation With AI-HPSD Strategy Versus Standard Settings
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Ablation Index Guided High-Power Short-Duration Strategy|PROCEDURE: Standard Radiofrequency Ablation Technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
Status: ENROLLING_BY_INVITATION
Conditions: Obesity|Overweight
Interventions: DRUG: Orforglipron|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: OCT Study of the MGuard Prime Stent in Patients With Heart Attacks
Status: WITHDRAWN
Conditions: ST Segment Elevated Myocardial Infarction
Interventions: DEVICE: MGuard Prime|DEVICE: Control BMS DES
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.
Status: COMPLETED
Conditions: Respiratory Tract Infection
Interventions: BIOLOGICAL: RSVpreF|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine the Safety and Efficacy of Albiglutide in Patients With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: albiglutide|DRUG: insulin glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotic Prophylaxis in Rhinoplasty
Status: ENROLLING_BY_INVITATION
Conditions: Nasal Obstruction|Nasal Surgical Procedures
Interventions: DRUG: Intra-operative single intravenous(iv) dose of "cephalexin" 2 g or "clindamycin" 900 mg.|DRUG: Intra-operative single dose (iv) of "cephalexin" 2 g or "clindamycin" 900 mg and postoperative oral dose of "cephalexin" 250mg (every 4 hours) or "clindamycin" 150mg(every 6 hours) for 3 days
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Efficacy and Pharmacokinetics Study of ALD518 in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: BIOLOGICAL: ALD518|BIOLOGICAL: Infusion without ALD518'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease
Status: TERMINATED
Conditions: Asthma|Bronchiectasis|Cystic Fibrosis
Interventions: DEVICE: Perform three multiple breath nitrogen washout tests (N2-MBW-test)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of SXL01 in Patients With Metastatic Castration-Resistant Prostate Cancer (PROSTIRNA)
Status: WITHDRAWN
Conditions: Prostatic Cancer, Castration-Resistant
Interventions: DRUG: SXL01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Pharmacokinetics and Safety Between the Treatment of CKD-383 and Treatment of CKD-501, D745, D150, and D029
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: CKD-383|DRUG: CKD-501, D745, D150, D029
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Oxidant Gel and Anti-oxidant Gel on Wound Healing After Gingival Depigmentation
Status: RECRUITING
Conditions: Gingival Pigmentation
Interventions: DRUG: blue®m Gel|DRUG: NBF GINGIVAL GEL®|DRUG: COE-PAK™
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Addition of a Focal Boost in External Beam Radiotherapy for Locally Advanced Prostate Cancer by Online Adaptive MR-guided Radiotherapy
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer|Prostate Neoplasm
Interventions: RADIATION: Ultrahypofractionated MR-guided radiotherapy boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Health Equity and Rural Education (HERE!) Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Behavioral Symptoms|Community Health Workers|Social Determinants of Health|Educational Problems
Interventions: BEHAVIORAL: School-Based Community Health Worker (SB-CHW) intervention|BEHAVIORAL: Enhanced Usual Care (EUC) Methods
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Dioxidin Versus Miramistin in Superficial Pyoderma
Status: COMPLETED
Conditions: Pyoderma
Interventions: DRUG: Hydroxymethylquinoxalindioxyde|DRUG: Benzyl-dimethyl-[3-(tetradecanoylamino)propyl]azanium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT