pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Intramural Needle Ablation for the Treatment of Refractory Ventricular Arrhythmias
Status: COMPLETED
Conditions: Ventricular Arrythmia
Interventions: DEVICE: Intramural Needle Ablation|PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Intramuscular Gene Transfer of rAAV1.CMV.huFollistatin344 Trial to Patients With Duchenne Muscular Dystrophy
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: rAAV1.CMV.huFollistin344
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cord Blood Cells in Patients With Acute SCI
Status: RECRUITING
Conditions: Spinal Cord Injury, Acute
Interventions: BIOLOGICAL: Multiple systemic (i.v.) administration of allogenic non-related group- and rhesus-compatible mononuclear cord blood cells|OTHER: Control vehicle (sterile saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Efficacy and Safety of PF-04523655 Versus Laser in Subjects With Diabetic Macular Edema
Status: TERMINATED
Conditions: Diabetic Retinopathy|Diabetes Complications
Interventions: PROCEDURE: Laser Treatment|DRUG: PF-04523655 high|DRUG: PF-04523655 middle|DRUG: PF-04523655 low
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: LEO 29102 Cream in the Treatment of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: LEO 29102|DRUG: Elidel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Non-invasive Prenatal Diagnostic Validation Study
Status: COMPLETED
Conditions: Chromosome 13 Aneuploidy|Chromosome 18 Aneuploidy|Chromosome 21 Aneuploidy|Sex Chromosome Aberrations|Other Microdeletions
Interventions: PROCEDURE: Blood draw|PROCEDURE: Cheek swab/Saliva Sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Chondrochymal® for Subjects With Knee Osteoarthritis (Knee OA)
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Bone marrow mesenchymal stem cells|DRUG: hyaluronic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study to Examine the Patients With Isolated Systolic Hypertonia (ISH) Under Therapy With Eneas® (NIS ENEAS ISH)
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Enalapril maleate (10 mg) + nitrendipine (20 mg)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Paracetamol in Addition to Morphine to Improve Analgesia in the Emergency Department
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Paracetamol|DRUG: Placebo|DRUG: Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis
Status: COMPLETED
Conditions: Surgical Wound Infection
Interventions: DRUG: Extra dosage - cefuroxime (750mg) I.V|PROCEDURE: Colorectal Surgery|DRUG: Ciprofloxacin 750 mg oral|DRUG: Metronidazole 250 mg oral|DRUG: Cefuroxime 1.5 g Intravenous|DRUG: Metronidazole 1 g Intravenous
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Opioid Induced Bowel Dysfunction in Patients Undergoing Cesarean Section
Status: ACTIVE_NOT_RECRUITING
Conditions: Constipation|Pain, Postoperative
Interventions: PROCEDURE: Caesarean section|DRUG: Oxycodone|DRUG: oxycodone-naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of HS-10384 in Participants of Chinese Postmenopausal Women
Status: RECRUITING
Conditions: Vasomotor Symptoms
Interventions: DRUG: HS-10384 tablets|DRUG: HS-10384-matched placebo tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients
Status: RECRUITING
Conditions: COVID-19
Interventions: DRUG: Remdesivir|DRUG: Imatinib Mesylate|DRUG: Dexamethasone|DRUG: Cenicriviroc|DRUG: Icatibant|DRUG: Apremilast|BIOLOGICAL: dornase alfa|DRUG: Celecoxib|DRUG: Famotidine|BIOLOGICAL: IC14|DRUG: Aviptadil|BIOLOGICAL: narsoplimab|DRUG: Cyproheptadine|DRUG: Cyclosporine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Cognitive Flexibility in Mindfulness Intervention for Emotional Distress
Status: NOT_YET_RECRUITING
Conditions: Emotional Distress
Interventions: BEHAVIORAL: Mindfulness Intervention for Emotional Distress(MIED)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part, 12-Week Study of Etoricoxib as a Treatment for Rheumatoid Arthritis (RA) (MK-0663-107)
Status: COMPLETED
Conditions: Arthritis, Rheumatoid
Interventions: DRUG: Etoricoxib 60 mg|DRUG: Etoricoxib 90 mg|DRUG: Placebo to Etoricoxib 60 mg|DRUG: Placebo to Etoricoxib 90 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Automatic Administration of Oxygen During Respiratory Distress
Status: COMPLETED
Conditions: Acute Respiratory Distress Syndrome|Hypoxemia
Interventions: DEVICE: Device FreeO2 v2.0|DEVICE: Device FreeO2 v2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Nimotuzumab and Cisplatin/Radiotherapy for Locally Advanced Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Nimotuzumab|DRUG: Cisplatin|RADIATION: Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1b Study of STMC-103H in Multi-Sensitized Allergic Subjects Who Are Otherwise Healthy
Status: UNKNOWN
Conditions: Atopic Immunoglobulin E-Mediated Allergic Disorder
Interventions: BIOLOGICAL: STMC-103H|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Recurrent Colon Cancer|Recurrent Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: DRUG: MEK inhibitor MEK162|DRUG: leucovorin calcium|DRUG: fluorouracil|DRUG: oxaliplatin|OTHER: pharmacological study|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing RG1-VLP Vaccine to Prevent HPV-related Cancers
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus-Related Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|BIOLOGICAL: HPV16 RG1 VLP Vaccine|OTHER: Questionnaire Administration|BIOLOGICAL: Recombinant Human Papillomavirus Nonavalent Vaccine|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Non-invasive Neuromodulation NESA in Neuroefficiency in Basketball Players
Status: COMPLETED
Conditions: Basketball Player
Interventions: DEVICE: Non-invasive Neuromodulation|DEVICE: Placebo Non-invasive Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: NPWT for Abdominal Incisions in DIEP Reconstructions: A RCT
Status: WITHDRAWN
Conditions: Breast Cancer|Surgical Site Infection|Wound Dehiscence
Interventions: DEVICE: Negative Pressure Wound Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Status: UNKNOWN
Conditions: Post-Surgical Ocular Pain|Post-Surgical Ocular Inflammation
Interventions: DRUG: Dextenza 0.4Mg Ophthalmic Insert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potassium-Competitive Acid Blocker Versus pROton-Pump Inhibitor for GastroproTECTion Strategies In Patients at High Gastro-Intestinal Bleeding Risk Receiving Antithrombotic Therapy
Status: RECRUITING
Conditions: Coronary Artery Disease|Percutaneous Coronary Intervention|Acute Coronary Syndrome|Myocardial Infarction
Interventions: DRUG: PPI|DRUG: P-CAB 50
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GLPG3970|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Using Ca-41 Methodology to Assess the Impact of Different Vitamin D Supplementation Levels on Postmenopausal Bone Health
Status: COMPLETED
Conditions: Osteopenia
Interventions: DIETARY_SUPPLEMENT: vitamin D|BEHAVIORAL: exercise program (rebounding on a trampoline)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Phase III Trial of Pertuzumab Retreatment in Previously Pertuzumab Treated Her2-Positive Advanced Breast Cancer
Status: UNKNOWN
Conditions: HER2-positive Locally Advanced or Metastatic Breast Cancer
Interventions: DRUG: Trastuzumab|DRUG: Pertuzumab|DRUG: Docetaxel|DRUG: Paclitaxel|DRUG: Nab-paclitaxel|DRUG: Vinorelbine|DRUG: Eribulin|DRUG: Capecitabine|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study on the Impact of Rabeprazole-induced Elevated Stomach pH on APO-Dabigatran Exposure in Healthy Volunteers
Status: COMPLETED
Conditions: Atrial Fibrillation|Venous Thromboembolism
Interventions: DRUG: RABEprazole 20 Mg Oral Delayed Release Tablet|DRUG: APO-Dabigatran 150mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of ThisCART19A Bridging Hematopoietic Stem Cell Transplantation in Patients With Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia
Status: NOT_YET_RECRUITING
Conditions: Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited
Interventions: DRUG: ThisCART19A|DRUG: Fludarabine Oral Tablet|DRUG: Cyclophosphamide|DRUG: VP-16|PROCEDURE: HSCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Repositioning of a New Suture-Method Catheter for Adductor Canal Block
Status: COMPLETED
Conditions: Anesthesia|Pain, Postoperative|Pain|Pain, Joint
Interventions: PROCEDURE: SAX catheter insertion|PROCEDURE: LAX catheter insertion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Tagraxofusp in Treating Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm After Stem Cell Transplant
Status: TERMINATED
Conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm
Interventions: BIOLOGICAL: Tagraxofusp-erzs
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Positive End-expiratory Pressure on Hepatic Venous Flow
Status: UNKNOWN
Conditions: Valvular Heart Disease
Interventions: PROCEDURE: low PEEP conventional ventilation|PROCEDURE: moderate PEEP conventional ventilation|PROCEDURE: low PEEP protective ventilation|PROCEDURE: moderate PEEP protective ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Malignancies
Interventions: DRUG: Ami-LC-MD|DRUG: Ami-LC|DRUG: Ami-HC|DRUG: Ami-HC-CF|DRUG: Lazertinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Panitumumab IRDye800 Optical Imaging Study
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Panitumumab IRDye 800|DEVICE: da Vinci Firefly|DEVICE: IMAGE1 + ICG Hopkins telescope and/or VITOM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Multimodal Assessment of the Neurological Prognosis of Patients With Brain Lesions on ExtraCorporeal Life Support
Status: UNKNOWN
Conditions: Brain-injured Patients on Extracorporeal Life Support
Interventions: OTHER: clinical examinations|OTHER: neurological assessment when a neurological event occurs|OTHER: mortality assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis
Status: COMPLETED
Conditions: Eosinophilic Esophagitis|Gastroesophageal Reflux Disease|EE|GERD
Interventions: DRUG: Esomeprazole|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Vortioxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Vitamin D in Prevention of Dengue Haemorrhagic Fever and Dengue Shock Syndrome
Status: RECRUITING
Conditions: Dengue Fever
Interventions: DRUG: Arm-2 : 2,00,000 IU Vitamin D3 oral solution , Arm-3: 4,00,000 IU Vitamin D3 oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Observational Study of the Mean Duration of Trastuzumab (Herceptin) Treatment in Participants With Early or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Trastuzumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Pulsed Radiofrequency of the Saphenous Nerve in the Management of Knee Arthroplasty Pain
Status: COMPLETED
Conditions: Arthroplasty|Replacement|Knee|Pain
Interventions: PROCEDURE: Pulsed radiofrequency of the saphenous nerve before knee replacement surgery|PROCEDURE: Mock incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age
Status: COMPLETED
Conditions: Hypertension|Chronic Kidney Disease
Interventions: DRUG: Valsartan|DRUG: amlodipine|DRUG: Hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ketamine + Magnesium for Chronic Cluster Headache (KETALGIA)
Status: RECRUITING
Conditions: Refractory Chronic Cluster Headache
Interventions: DRUG: Ketamine + Magnesium sulfate (drug combination)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Irinotecan, Oxaliplatin, Plus TS-1 in Untreated Metastatic Gastric Cancer
Status: COMPLETED
Conditions: Stomach Neoplasms
Interventions: DRUG: Irinotecan, Oxaliplatin, TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Women With Stage II or Stage III Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: cyclophosphamide|DRUG: epirubicin hydrochloride|DRUG: fluorouracil|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Comparison of the PrimAry Long Versus Short Coverage With Drug-Eluting Stents for Long FemoRopopliteal Artery DiseasE (PARADE II): Investigator-initiated Clinical Study
Status: UNKNOWN
Conditions: Femoropopliteal Artery Disease
Interventions: DEVICE: Long stenting using drug-eluting stent (Zilver PTX)|DEVICE: Spot stenting using drug-eluting stent (Zilver PTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravitreal Aflibercept Injection in Vision Impairment Due to DME
Status: COMPLETED
Conditions: Diabetes Mellitus|Macular Edema
Interventions: BIOLOGICAL: VEGF Trap-Eye (BAY86-5321)|BIOLOGICAL: VEGF Trap-Eye (BAY86-5321)|PROCEDURE: Macular Laser Photocoagulation (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ambu Auragain and I-Gel Supraglottic Airways in Adult Patients at an Ambulatory Surgery Center
Status: COMPLETED
Conditions: Anesthesia|Surgery
Interventions: DEVICE: I-Gel Laryngeal Mask Airway|DEVICE: Ambu Auragain Laryngeal Mask Airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RCT on the Efficacy of Dexamethasone Versus Methyl Prednisolone in Covid-19 Infected Patients With High Oxygen Flow
Status: UNKNOWN
Conditions: COVID-19 Pandemic
Interventions: DRUG: Dexamethasone|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: N-Terminal Pro-B-Type Natriuretic Peptide and Troponin Levels as Markers of Hemodynamic Stability in Very Low Birth Weight Infants During the First Days of Life
Status: WITHDRAWN
Conditions: Hypotension|Very Low Birth Weight Infants|Ventricular Dysfunction|Prematurity
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclophosphamide, Lenalidomide and Dexamethasone (CLD) for Previously Treated Patients With AL Amyloidosis
Status: COMPLETED
Conditions: Amyloidosis
Interventions: DRUG: cyclophosphamide|DRUG: lenalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Resvida, a Comparison With Calorie Restriction Regimen
Status: COMPLETED
Conditions: Obesity|Metabolic Syndrome|Diabetes|Aging
Interventions: DIETARY_SUPPLEMENT: resveratrol|OTHER: placebo|BEHAVIORAL: Calorie Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Resveratrol: A Potential Anti- Remodeling Agent in Heart Failure, From Bench to Bedside
Status: UNKNOWN
Conditions: Dilated Cardiomyopathy
Interventions: OTHER: Resveratrol|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of CJ30001 and HKB0701/SLM0807 in Healthy Subject
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: Period I : HKB0701 and SLM0807, Period II : CJ30001|DRUG: Period I : CJ30001, Period II : HKB0701 and SLM0807
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination of Autologous MSC and HSC Infusion in Patients With Decompensated Cirrhosis
Status: COMPLETED
Conditions: Cirrhosis, Liver
Interventions: COMBINATION_PRODUCT: CD 34 and MSC infusion|DRUG: Standard of care for Cirrhosis management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cyclofem® for the Treatment of Irregular Uterine Bleeding in Implant Contraceptive Users
Status: UNKNOWN
Conditions: Uterine Bleeding
Interventions: DRUG: Cyclofem
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Recombinant Human Angioendostatin /PD-1 Mab Combined With First-line Chemotherapy in the Treatment of Driver Gene Negative Advanced NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer|Endostatin
Interventions: DRUG: Endostatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study)
Status: COMPLETED
Conditions: Huntington Disease
Interventions: DRUG: (2)-epigallocatechin-3-gallate (EGCG)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cefuroxime vs Ceftriaxone for SSI Prevention in Neurosurgery
Status: COMPLETED
Conditions: Surgical Site Infection|Antibiotics Prophylaxis
Interventions: DRUG: Cefuroxime (Zinnat®)|DRUG: Ceftriaxone (Rocephin®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients
Status: RECRUITING
Conditions: Metastatic Non-small Cell Lung Cancer (NSCLC)|Non-small Cell Lung Cancer Metastatic|Non-small Cell Lung Cancer Stage II|Non Small Cell Lung Cancer Stage III|Small-cell Lung Cancer|Non-small Cell Lung Cancer Stage I
Interventions: OTHER: data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Enhanced Therapeutic Effect of Adipose Stromal Vascular Fraction Added With Human Platelet Lysate in Treatment of Osteoarthritis
Status: UNKNOWN
Conditions: Assessment of the Trophic and Anti-inflammatory Effect of SVF Added With HPL
Interventions: OTHER: isolation of waste material and culturing with different supplement culture media
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness of Three Anti-HIV Drugs Combined in One Pill (Trizivir)
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Pilot Testing of an Online Rehabilitation Intervention for People With Heart Failure (PORIAS-HF).
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure
Interventions: PROCEDURE: Exercise|PROCEDURE: Self-managed exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pyloric or Pseudopyloric Metaplasia of the Corpus Mucosa in Autoimmune Gastritis
Status: ENROLLING_BY_INVITATION
Conditions: Autoimmune Diseases|Helicobacter Pylori Gastritis|Anemia, Pernicious|Metaplasia|Gastritis, Atrophic
Interventions: DIAGNOSTIC_TEST: Assess pyloric or pseudopyloric metaplasia of corpus by H&E stains|DIAGNOSTIC_TEST: Assess pyloric or pseudopyloric metaplasia of corpus by TFF2 immunohistochemistry stains|DIAGNOSTIC_TEST: The assessment of corpus-predominant gastritis index (CGI), Operative Link for Gastritis Assessment (OLGA), and Operative Link on Gastric Intestinal Metaplasia assessment (OLGIM)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photobiomodulation for the Management of Temporomandibular Disorder Pain
Status: TERMINATED
Conditions: Pain Related to TMD
Interventions: DEVICE: THOR® laser system|DEVICE: sham THOR® laser system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalpiciclib, Fulvestrant, Trastuzumab and Pertuzumab in HR Positive, HER2 Positive Metastatic Breast Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Dalpiciclib|DRUG: Fulvestrant|DRUG: Pertuzumab|DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topical Naloxone to Diagnose Ocular Pain
Status: COMPLETED
Conditions: Dry Eye Syndromes|Neuropathic Pain
Interventions: DRUG: Naloxone Hydrochloride 0.4 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Trauma Infant Neurological Score (TINS) as a Prognostic Factor and Guideline for CT Scan in Infants 24 Months Old or Less
Status: UNKNOWN
Conditions: TO FIND THE CORRELATION BETWEEN TINS SCORE OUTCOME
Interventions: OTHER: NONE . OBSERVATIONAL
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: First-in-human Single Ascending Dose Study of LNA043 in Patients Scheduled for Total Knee Replacement
Status: COMPLETED
Conditions: Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
Interventions: DRUG: LNA043|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Dermacyd PH_DETINBACK (Lactic Acid) Sweet Flower - Compatibility
Status: COMPLETED
Conditions: Hygiene
Interventions: DRUG: Dermacyd PH_DETINBACK (Lactic Acid)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Dietary Fibre and Metabolic Benefits
Status: COMPLETED
Conditions: Glucose Tolerance
Interventions: OTHER: Cereal product 1|OTHER: Cereal product 2|OTHER: Cereal product 3|OTHER: Cereal product 4|OTHER: Cereal product 5|OTHER: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)
Status: RECRUITING
Conditions: AL Amyloidosis|Light Chain (AL) Amyloidosis|Systemic Light Chain Disease
Interventions: DRUG: Venetoclax|DRUG: Dexamethasone|DRUG: Daratumumab|DEVICE: Cyclin D1 gene (CCDN1) /immunoglobulin heavy chain (IGH) fluorescence in situ hybridization (FISH) assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ORCA - Oracea® for Rosacea: A Community-based Assessment
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: doxycycline (Oracea®) 40 mg modified release as monotherapy|DRUG: doxycycline (Oracea®) 40 mg modified release as add-on therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Arom Digest Slim on Metabolic Profile and Food Behaviour in Overweight Persons
Status: UNKNOWN
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Arom Digest Slim|BEHAVIORAL: Nutritional changes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of HIL-214 in Healthy Japanese Infants
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastroenteritis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: HIL-214
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Reward Message with standard introduction|BEHAVIORAL: Reward Message with culturally tailored introduction|BEHAVIORAL: Threat/Self-efficacy with standard introduction|BEHAVIORAL: Threat/Self-efficacy with culturally tailored introduction|BEHAVIORAL: Social norms message with standard introduction|BEHAVIORAL: Social norms message with culturally tailored introduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Incomes of Nutritional Support Modalities in Hemodialysis Patients With Severe Malnutrition
Status: COMPLETED
Conditions: Severe Malnutrition
Interventions: DIETARY_SUPPLEMENT: Oral Nutritional Support; Nutrena|DIETARY_SUPPLEMENT: Intradialytic Parenteral Nutrition; Kabiven central
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dabrafenib and Trametinib for the Treatment of Patients With Stage III-IV BRAF Mutant Melanoma That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Melanoma
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|DRUG: Dabrafenib Mesylate|PROCEDURE: Echocardiography|PROCEDURE: Multigated Acquisition Scan|PROCEDURE: Positron Emission Tomography|DRUG: Trametinib Dimethyl Sulfoxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp
Status: NOT_YET_RECRUITING
Conditions: Shared Decision Making|Colonic Polyp|Decision Aids|Rectal Polyp|Colorectal Polyp|Colorectal Cancer
Interventions: OTHER: Shared Decision Making using a Patient Decision Aid.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Use of International Ovarian Tumor Analysis and Assessment of Adnexal Neoplasia in Differentiating Malignant and Benign Adnexal Masses
Status: UNKNOWN
Conditions: Adnexal Mass
Interventions: PROCEDURE: Excision of adnexal mass through laprotomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Nicoderm Transdermal Patch|DRUG: Nicotine Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multimodal Intervention for Community-dwelling Individuals With Unwanted Loneliness
Status: COMPLETED
Conditions: Loneliness|Mental Health Disorder
Interventions: BEHAVIORAL: Music therapy for community-dwelling individuals with unwanted loneliness|BEHAVIORAL: Health education for community-dwelling individuals with unwanted loneliness|BEHAVIORAL: Physical exercise for community-dwelling individuals with unwanted loneliness
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study to Test How Well Patients With Plaque Psoriasis Tolerate BI 730357 Over a Longer Period and How Effective it is
Status: TERMINATED
Conditions: Psoriasis
Interventions: DRUG: BI 730357|DRUG: Placebo to match BI 730357
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Remote Ischemic Preconditioning Preceding Coronary Artery Bypass Grafting on Inducing nEuroprotection
Status: COMPLETED
Conditions: Brain Ischemia|Postoperative Confusion
Interventions: PROCEDURE: Remote ischemic preconditioning|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Yogurt in Cancer Patient With Moderate Gastrointestinal (GI) Symptoms
Status: WITHDRAWN
Conditions: Malignant Neoplasms of Independent (Primary) Multiple Sites
Interventions: OTHER: Tongue Assessment|OTHER: Stool Sample|BEHAVIORAL: Questionnaires|DEVICE: Holter Monitor|OTHER: Yogurt
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of BIPAMS for Restless Legs Syndrome in Adults With Multiple Sclerosis: A Pilot Study
Status: COMPLETED
Conditions: Multiple Sclerosis|Restless Legs Syndrome
Interventions: BEHAVIORAL: Behavioral Intervention (BIPAMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety and Efficacy of the ReLARC Inserter During the Insertion Procedure of GYNEFIX Intrauterine Copper Bearing Contraceptive Device With a Follow-up of 3 Years.
Status: RECRUITING
Conditions: Contraception
Interventions: DEVICE: ReLARC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Advancing Niacin by Inhibiting Flushing (ANTI-FLUSH)
Status: COMPLETED
Conditions: Flushing
Interventions: DIETARY_SUPPLEMENT: Quercetin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of Educational Intervention on Sustainable Breastfeeding: The GREEN MOTHER Project
Status: RECRUITING
Conditions: Healthy Diet|Health Behaviour|Environmental-Pollution-Related Condition|Mothers|Child, Only
Interventions: BEHAVIORAL: The educational programme on sustainable and healthy diet and breastfeeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Comparison of Pharmacokinetics and Safety of HS627(2 Specifications) Versus PERJETA With a Single Injection
Status: COMPLETED
Conditions: Similarity of Pharmacokinetics and Safety
Interventions: DRUG: HS627(210mg/7ml)|DRUG: HS627(420mg/14ml)|DRUG: Perjeta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies to Improve the Experience of Gynaecological Screening
Status: ENROLLING_BY_INVITATION
Conditions: Cervical Cancer
Interventions: OTHER: Changed clinical context|BEHAVIORAL: Extra time allotted|BEHAVIORAL: RLP-information
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD)
Status: COMPLETED
Conditions: Sudden Cardiac Arrest
Interventions: BEHAVIORAL: Nursing Telephone Support Protocol|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Comparison of Continuous Sternal ECG Patch Monitors (Carnation and Zio) Trial
Status: COMPLETED
Conditions: Syncope|Presyncope|Atrial Fibrillation|Supraventricular Tachycardia
Interventions: DEVICE: EKG Patch monitors (Zio and Carnation)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of ARQ-151 Cream in Adolescents and Adults With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Roflumilast Cream 0.05%|DRUG: Roflumilast Cream 0.15%|DRUG: Vehicle Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ImmunoPET With an Anti-CD8 Imaging Agent
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Cancer|Unresectable Malignant Neoplasm
Interventions: OTHER: Anti-CD8 PET imaging agent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Application of the Web-based Acceptance and Commitment Therapy for Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DEVICE: Web-based ACT|BEHAVIORAL: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate SAGE-217 in Participants With Essential Tremor
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DRUG: SAGE-217|DRUG: SAGE-217|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Related Factors With Resilience in Caregivers Whose Child With Leukemia
Status: UNKNOWN
Conditions: Condition 1. Children With ALL Are Still Alive and the Age of 18 Years of Age.|Condition 2. Has Been Completed to Guide the Treatment Regimen Were in Remission.|Condition 3. Caregiver Can or Taiwanese Language Communicator.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of Interventions to Teach Respiratory Inhaler Technique (E-TRaIN)
Status: COMPLETED
Conditions: Asthma|Chronic Obstructive Pulmonary Disease (COPD)
Interventions: BEHAVIORAL: Teach-To-Goal|BEHAVIORAL: Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of Initial Steroid Treatment in Young Children With Nephrotic Syndrome
Status: WITHDRAWN
Conditions: Steroid-Sensitive Nephrotic Syndrome
Interventions: DRUG: Prednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Fatty Acids on Octadecanoid Production and Biological Actions in Obesity-induced Inflammation
Status: COMPLETED
Conditions: Obesity|Inflammation
Interventions: DIETARY_SUPPLEMENT: Capsules containing flax oil|DIETARY_SUPPLEMENT: Capsules containing DHA-enriched fish oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RENOVATE Palliative: HFNC vs. Standard Respiratory Support in Patients With Do-Not-Intubate Order and ARF
Status: TERMINATED
Conditions: Care, Palliative|Respiratory Failure
Interventions: DEVICE: High Flow Nasal Cannula|OTHER: Standard respiratory support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthetic Premedication With a Cannabis Extract (Cannapremed)
Status: RECRUITING
Conditions: Pain, Postoperative|Postoperative Nausea and Vomiting|Anxiety
Interventions: DRUG: Tetrahydrocannabinol|DRUG: Dummy oromucosal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effect of Intravitreal Dexamethasone Implant in Refractory Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema
Interventions: DRUG: Intravitreal dexamethasone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Hepatic Arterial Infusional Chemotherapy After Curative Resection of Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Adjuvant group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: TMQLB Versus TPVB for Acute Pain and Quality of Recovery After Laparoscopic Renal Surgery
Status: TERMINATED
Conditions: Nerve Block, Nephrectomy, Analgesia
Interventions: PROCEDURE: TMQLB group 1|PROCEDURE: TMQLB group 2|PROCEDURE: TPVB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of HB0034 in Patients With Generalized Pustular Psoriasis (GPP)
Status: RECRUITING
Conditions: Generalized Pustular Psoriasis (GPP)
Interventions: DRUG: HB0034|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans
Status: RECRUITING
Conditions: Post Traumatic Stress Disorder|Opioid-use Disorder
Interventions: DRUG: Lofexidine|DRUG: Placebo oral tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA
Status: RECRUITING
Conditions: Logopenic Progressive Aphasia|Primary Progressive Aphasia
Interventions: DEVICE: High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment|DEVICE: Sham + "Repeat After Me" (RAM) Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients
Status: RECRUITING
Conditions: Alcohol Use Disorder
Interventions: BEHAVIORAL: Peer recovery coaching (PRC)|BEHAVIORAL: Brief Intervention (SBIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: App-based Intervention for Treating Insomnia Among Patients With Epilepsy
Status: COMPLETED
Conditions: Epilepsy|Insomnia
Interventions: BEHAVIORAL: Sleep Health|OTHER: Patient education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of XL844 in Subjects With Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: XL844
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Levodopa-induced Dyskinesias by Transcranial Static Magnetic Field Stimulation (tSMS)
Status: COMPLETED
Conditions: Dyskinesia, Medication-Induced|Parkinson's Disease
Interventions: DEVICE: tSMS|DEVICE: sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioimpedance and Hand-held Echocardiographay for Clinical Decision-making in Treatment of Cardio-renal Syndrome Type I
Status: WITHDRAWN
Conditions: Cardio-Renal Syndrome
Interventions: OTHER: Providing caring physicians with hemodynamic variables
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-077)(COMPLETED)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: MK0663, etoricoxib|DRUG: Comparator: celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Monitoring of the End-tidal Carbon Dioxide (EtCO2) as a Severity Criterion in COPD Exacerbations
Status: RECRUITING
Conditions: Pulmonary Disease, Chronic Obstructive|Exacerbation Copd
Interventions: DIAGNOSTIC_TEST: End-Tidal CO2 measurement during COPD exacerbation
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p