pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effects of Mifepristone on Biomarkers of Metabolic Function and Neuropsychological Performance Among Middle-Aged and Older Individuals
Status: COMPLETED
Conditions: Depression
Interventions: DRUG: 28 days treatment with Mifepristone.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration)
Status: COMPLETED
Conditions: Macular Degeneration
Interventions: BIOLOGICAL: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)|DRUG: Visudyne
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PaTcH Study: A Phase 2 Study of Trametinib and Hydroxychloroquine in Patients With Metastatic Refractory Pancreatic Cancer
Status: RECRUITING
Conditions: Pancreatic Cancer
Interventions: DRUG: Trametinib|DRUG: Hydroxychloroquine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PGTai Results for Embryos Cultured in Sequential Versus Single Step Media
Status: UNKNOWN
Conditions: Infertility|Aneuploidy Rate|Mosaicism
Interventions: OTHER: Single step media|OTHER: Sequential media
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Evaluate the Immunogenicity and Safety of Sarilumab Administered as Monotherapy in Patients With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: sarilumab SAR153191 (REGN88)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Guselkumab Therapy in Participants With Moderately to Severely Active Ulcerative Colitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Colitis, Ulcerative
Interventions: DRUG: Guselkumab Dose 1|DRUG: Guselkumab Dose 2|DRUG: Guselkumab Dose 3|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Oral Natural Extract for the Treatment of Senile Purpura
Status: UNKNOWN
Conditions: PURPURA
Interventions: DIETARY_SUPPLEMENT: Citrus Bioflavanoid Blend|DIETARY_SUPPLEMENT: Calcium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Validity and Reliability of High-Activity Arthroplasty Score
Status: RECRUITING
Conditions: Arthroplasty Complications
Interventions: OTHER: High-Activity Arthroplasty Score (HAAS)|OTHER: Western Ontario and McMaster Universities osteoarthritis score (WOMAC)|OTHER: The Knee injury and Osteoarthritis Outcome Score (KOOS)|OTHER: The Forgotten Joint Score-12 (FJS-12)|OTHER: EQ-5D-5L|OTHER: Numerical pain scale (NPS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Testing Ado-Trastuzumab Emtansine as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol Q)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: BIOLOGICAL: Trastuzumab Emtansine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Marketing Study of the Safety of Prevenar (Pneumococcal Conjugate Vaccine, 7-valent)
Status: COMPLETED
Conditions: Vaccines, Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: Pneumococcal Conjugate Vaccine, 7-valent (Prevenar)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA)
Status: TERMINATED
Conditions: HIV Infection
Interventions: DRUG: Maraviroc, Darunavir/r|DRUG: current antiretroviral therapy with 3 drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Syndrome in Psoriasis and Psoriatic Arthritis and Correlation With Serum Omentin and Visfatin Levels
Status: COMPLETED
Conditions: Psoriasis Vulgaris|Psoriatic Arthritis|Metabolic Syndrome
Interventions: DIAGNOSTIC_TEST: omentin, visfatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Stable Iron Isotope Method in HIV+ and HIV- Children
Status: COMPLETED
Conditions: Iron-deficiency
Interventions: DIETARY_SUPPLEMENT: FeFum fortified maize test meal|DIETARY_SUPPLEMENT: FeSO4 fortified LNS|DIETARY_SUPPLEMENT: FeSO4 supplement|DIETARY_SUPPLEMENT: FeSO4 fortified fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PD-1 Immune Checkpoint Inhibitors and Immune-Related Adverse Events: a Cohort Study
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung|Immune-Related Adverse Events
Interventions: DRUG: PD-1 inhibitor|DRUG: Chemotherapy Drugs, Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effectiveness of the Implementation of a Standardized Care Plan to Improve Fear of Falling and Incidence of Falls
Status: ACTIVE_NOT_RECRUITING
Conditions: Falls|Fear of Falling|Nursing
Interventions: PROCEDURE: Health education workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate
Status: TERMINATED
Conditions: Hypertension
Interventions: DRUG: Metoprolol|DRUG: Nebivolol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Innovative Biotechnological Production of Antioxidant Products
Status: COMPLETED
Conditions: Oxidative Stress|Inflammation|Body Weight|Homocystine; Metabolic Disorder
Interventions: DIETARY_SUPPLEMENT: Hydroxytyrosol/Essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Childhood Outcomes of Preterm Brain Abnormalities
Status: RECRUITING
Conditions: Premature Birth|Neurodevelopmental Disorders|Brain Development Abnormality|Brain Lesion
Interventions: DIAGNOSTIC_TEST: MRI|DIAGNOSTIC_TEST: Neurodevelopmental/Neuropsychological Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHD
Status: NOT_YET_RECRUITING
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: Fostamatinib|DRUG: Ruxolitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Accuracy of a Breast Cancer Locator (BCL) in Patients With Palpable Cancers
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DEVICE: Breast Cancer Locator (BCL)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adenocarcinoma of the Pancreas
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Cyclophosphamide|DRUG: GVAX|DRUG: Pembrolizumab|DRUG: IMC-CS4
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Relapsing Multiple Sclerosis
Interventions: DRUG: Fenebrutinib|DRUG: Teriflunomide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of the Use of NewSpringForMe on Transplanted Patients' Quality of Life and Support
Status: RECRUITING
Conditions: Hematologic Diseases|Bone Marrow Transplantation|Hematopoietic Stem Cell Transplantation
Interventions: DEVICE: NewSpringForMe digital solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Day 3 Embryo Cryopreservation: Metabolic and Viability Analysis
Status: COMPLETED
Conditions: Fertilization in Vitro|Preservation of Supernumerary Embryos
Interventions: PROCEDURE: Vitrification|PROCEDURE: Slow freezing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Dietary Folate and Phytate Zinc Absorption: Zinc Amino Acid Complexes vs. Zinc-chloride
Status: COMPLETED
Conditions: Dietary Zinc Absorption
Interventions: OTHER: Regular toast and juice|OTHER: High phytate toast and juice|OTHER: Regular toast and juice, with folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Registry Collecting Real World Evidence on Wound Care Treatments
Status: ENROLLING_BY_INVITATION
Conditions: Wounds and Injuries|Burns|Mohs Surgery|Diabetic Foot Ulcer Mixed|Venous Leg Ulcer|Non-healing Wound|Trauma Injury|Injury and Wounds|Degloving Injuries
Interventions: BIOLOGICAL: Advanced Treatment Modalities for wound and injuries|BIOLOGICAL: Standard of care|OTHER: Retrospective wound treatment data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Study to Compare the Pharmacokinetic Characteristics and Safety Between CKD-380 10mg and D308 10mg
Status: UNKNOWN
Conditions: Type II Diabetes Mellitus
Interventions: DRUG: D308 10mg Tab.|DRUG: CKD-380 10mg Tab.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Intravenously Administered Anti-LIGHT Monoclonal Antibody CBS001 in Healthy Volunteers
Status: TERMINATED
Conditions: Chronic Inflammatory Disease
Interventions: DRUG: CBS001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Anti-CD19 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma
Status: UNKNOWN
Conditions: Refractory B-Cell Lymphoma
Interventions: BIOLOGICAL: Anti-CD19 CAR NK Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia
Status: TERMINATED
Conditions: Peripheral Artery Disease
Interventions: DIAGNOSTIC_TEST: FlowMet-R|DIAGNOSTIC_TEST: ABI|DIAGNOSTIC_TEST: TBI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: L-arginine in Treatment as Usual in Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: L-Arginine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectivity and Safety of Metronidazole 1% Cream in Rosacea Therapy
Status: NOT_YET_RECRUITING
Conditions: Rosacea
Interventions: DRUG: Metronidazole 1% Cream,Top|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2, 12-Week, Double-Blind, Efficacy and Safety of GX-G6 in Patients With Uncontrolled Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: GX-G6|DRUG: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Different Dosages of Bioactive Wheat Peptides and Blood Pressure Level and CVD Risk Biomarkers in Healthy Subjects
Status: UNKNOWN
Conditions: Pre-hypertension
Interventions: OTHER: Comparisons of two kind of pasta with low or high content of wheat bioactive peptides (sequence Low->High)|OTHER: Comparisons of two kind of pasta with low or high content of wheat bioactive peptides (sequence High->Low)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prepare for Your Diabetes Care
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus With Hypoglycemia|Aging|Patient Activation
Interventions: BEHAVIORAL: Prepare for Your Diabetes Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride
Status: COMPLETED
Conditions: Spray|Pain|Safety Issues
Interventions: DRUG: Gebauer's Pain Ease Top Aerosol Mist Spray|DRUG: Gebauer's Ethyl Chloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma
Status: RECRUITING
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: DPPG2-TSL-DOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PTC in Personalizing Neoadjuvant Therapy for Patients With Advanced Gastrointestinal Tumor
Status: NOT_YET_RECRUITING
Conditions: Gastrointestinal Neoplasms
Interventions: OTHER: PTC drug screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Safety and Efficacy of XT-150 for Treatment of Neuropathic Pain
Status: TERMINATED
Conditions: Neuropathic Pain
Interventions: BIOLOGICAL: XT-150|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Januvia (Sitagliptin) in Healing Chronic Diabetic Foot Ulcers
Status: TERMINATED
Conditions: Type II Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma
Status: UNKNOWN
Conditions: Lymphoma
Interventions: BIOLOGICAL: bleomycin sulfate|DRUG: ABVD regimen|DRUG: Stanford V regimen|DRUG: dacarbazine|DRUG: doxorubicin hydrochloride|DRUG: etoposide|DRUG: mechlorethamine hydrochloride|DRUG: prednisone|DRUG: vinblastine sulfate|DRUG: vincristine sulfate|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Does Post Operative Pancreatic Fistula, After Left Sided Resections, Heal Faster After the Introduction of a Pancreatic Stent?
Status: UNKNOWN
Conditions: Healing Time of Post Operative Pancreatic Fistulas
Interventions: DEVICE: Pancreatic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of an Improved Two-piece Stoma Product for People Living With a Stoma
Status: COMPLETED
Conditions: Stoma Site Leakage
Interventions: DEVICE: Iris - new coupling|DEVICE: Sensura Mio Click
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Assessment of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 Peptide Antigens
Status: UNKNOWN
Conditions: Detection of Delayed-type Hypersensitivity Reactions to SARS-CoV-2 in Individuals Exposed to SARS-CoV-2
Interventions: BIOLOGICAL: TNX-2110|BIOLOGICAL: TNX-2120|BIOLOGICAL: TNX-2130|BIOLOGICAL: CANDIN|BIOLOGICAL: Diluent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ALFApump System Versus Standard of Care in Ascites Treatment
Status: COMPLETED
Conditions: Refractory or Recurrent Ascites
Interventions: DEVICE: ALFApump removal of ascites|PROCEDURE: Large volume paracentesis for removal of ascites
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Effectiveness of Epoetin Alfa in AIDS (Acquired Immunodeficiency Syndrome) Patients With Anemia Caused Both by Their Disease and by AZT (Zidovudine, an Antiviral Drug) Given as Treatment for Their Disease
Status: COMPLETED
Conditions: Anemia|Acquired Immunodeficiency Syndrome
Interventions: DRUG: epoetin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Weekly Paclitaxel Liposome Injection Plus Cisplatin in Preoperative Treatment of Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: paclitaxel liposome injection plus cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19
Status: RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: AD17002 + Formulation buffer|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cardio-Cerebrovascular Co-Prevention and Co-Management Based on Internet+
Status: UNKNOWN
Conditions: Cardiovascular Diseases|Myocardial Ischemia|Cerebrovascular Disorders|Stroke|Internet-Based Intervention
Interventions: BEHAVIORAL: Establishment of individual health records|BEHAVIORAL: Cardiovascular risk assessment|BEHAVIORAL: Popularization of medical knowledge|BEHAVIORAL: Personalized Reminders|DRUG: Routine treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)
Status: NOT_YET_RECRUITING
Conditions: Systemic Lupus Erythematosus|Lupus Nephritis|Autoimmune Diseases|Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis|Granulomatous Polyangiitis|Microscopic Polyangiitis|Systemic Sclerosis|Idiopathic Inflammatory Myopathies|Sjogren's Syndrome
Interventions: BIOLOGICAL: CD19- BCMA CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability, PK and PD of AM1030-CREAM in Patients With Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: AM1030-CREAM or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Telemedicine in Pediatric Intensive Care Units
Status: UNKNOWN
Conditions: Telemedicine|Critical Care|Pediatric|Adolescent|Intensive Care Units, Pediatric
Interventions: BEHAVIORAL: Telemedicine Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Long Term Stability, Survival and Tolerability of a (Novel) Baha® Implant System
Status: COMPLETED
Conditions: Conductive Hearing Loss
Interventions: DEVICE: Novel Implant BI300|DEVICE: Standard Implant BI300
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Magnetic System in Bariatric and General Surgery
Status: RECRUITING
Conditions: Surgery|Bariatric Surgery Candidate
Interventions: PROCEDURE: Magnetic Gastric Bypass|PROCEDURE: Magnetic Sleeve Gastrectomy|PROCEDURE: Revisional Bariatric Surgery|PROCEDURE: Nissen/Sleeve Gastrectomy with Magnetic Assistance|PROCEDURE: Mangetic General Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Whiplash-associated Disorders - Needling Treatments Pilot Study
Status: UNKNOWN
Conditions: Whiplash Injury
Interventions: PROCEDURE: Intramuscular Stimulation|PROCEDURE: myoActivation|PROCEDURE: Neural Prolotherapy|PROCEDURE: Sham Needling Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Safety and Pharmacokinetics of SK3530 Tablet in Renal Impaired Male Patients
Status: COMPLETED
Conditions: Renal Insufficiency|Kidney Diseases|Urologic Diseases
Interventions: DRUG: Mirodenafil
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors
Status: NOT_YET_RECRUITING
Conditions: Clinical Stage III Gastric Cancer AJCC v8|Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8|Clinical Stage IV Gastric Cancer AJCC v8|Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8|Locally Advanced Gastric Carcinoma|Locally Advanced Gastroesophageal Junction Adenocarcinoma|Locally Advanced Malignant Solid Neoplasm|Metastatic Gastric Carcinoma|Metastatic Gastroesophageal Junction Adenocarcinoma|Metastatic Malignant Solid Neoplasm|Unresectable Gastric Carcinoma|Unresectable Gastroesophageal Junction Adenocarcinoma|Unresectable Malignant Solid Neoplasm
Interventions: DRUG: Azenosertib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Echocardiography|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Trastuzumab Deruxtecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quercetin for Cardio-Skeletal Muscle Health and Estrogen Deficiency
Status: WITHDRAWN
Conditions: Menopause Related Conditions
Interventions: DRUG: Placebo oral soft chew|DRUG: Quercetin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy
Status: RECRUITING
Conditions: Spinal Muscular Atrophy (SMA)
Interventions: DRUG: RO7204239|DRUG: Placebo|DRUG: Risdiplam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Meditation-Relaxation (MR Therapy) for Sleep Paralysis.
Status: UNKNOWN
Conditions: Sleep Paralysis|Narcolepsy Type 1
Interventions: BEHAVIORAL: MR therapy.|BEHAVIORAL: breathing-distraction exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ledderhose Disease: Radiotherapy or Not?
Status: ACTIVE_NOT_RECRUITING
Conditions: Ledderhose Disease
Interventions: RADIATION: Radiotherapy|OTHER: Sham Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contingency Management for Smoking Cessation in Homeless Smokers
Status: COMPLETED
Conditions: Smoking|Homeless Persons
Interventions: DRUG: Bupropion|DRUG: Nicotine replacement therapy|BEHAVIORAL: Contingency Management
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intravenous Zanamivir in the Treatment of Hospitalized Patients With Influenza Infection
Status: COMPLETED
Conditions: Influenza, Human
Interventions: DRUG: Intravenous (IV) zanamivir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prehabilitation for EOC, Fallopian Tube, Primary Peritoneal Carcinoma and Pancreatic Cancer w/ NACT
Status: RECRUITING
Conditions: Ovarian Cancer|Epithelial Ovarian Cancer|Pancreatic Adenocarcinoma
Interventions: OTHER: Prehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the Jaw
Status: NOT_YET_RECRUITING
Conditions: Osteonecrosis of the Jaw
Interventions: PROCEDURE: Surgery with the use of L-PRF|PROCEDURE: Standard surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: First Time in Human (FTIH) Study to Evaluate Safety, Tolerability, Immunogenicity, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3511294 Administered Subcutaneously (SC) in Subjects With Mild to Moderate Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: GSK3511294|DRUG: Placebo|DRUG: Salbutamol/albuterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Using WeChat Applet to Intervene in the Home Functional Exercise of Patients After Anterior Cruciate Ligament Reconstruction Based on the Health Belief Model
Status: COMPLETED
Conditions: Anterior Cruciate Ligament Injury
Interventions: BEHAVIORAL: WeChat Mini Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Of The Effectiveness & Safety Of Lenalidomide Versus Chlorambucil As First Line Therapy For Elderly Patients With B-Cell CLL (The ORIGIN Trial)
Status: COMPLETED
Conditions: B-Cell Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Chlorambucil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil for Smoked Cocaine Self-Administration
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: DRUG: Modafinil 0 mg|DRUG: Modafinil 200 mg|DRUG: Modafinil 400 mg|DRUG: Cocaine 0 mg|DRUG: Cocaine 12 mg|DRUG: Cocaine 25 mg|DRUG: Cocaine 50 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors
Status: RECRUITING
Conditions: Critical Illness|Cognitive Impairment|Circadian Dysrhythmia|Intensive Care Unit Delirium|Aging
Interventions: BEHAVIORAL: COG-AM|BEHAVIORAL: COG-PM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Post-traumatic Stress Disorder (PTSD) in Patients Monitored for Cytomegalovirus (CMV) Seroconversion During Pregnancy,
Status: COMPLETED
Conditions: Mothers|Cytomegalovirus Infections|Pregnancy Related
Interventions: OTHER: Assessment of post-traumatic stress disorder using the Perinatal Post-traumatic Stress Disorder)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Structured Advance Care Planning Guide Among Patients With Advanced Illness in Hospital Care Settings
Status: COMPLETED
Conditions: End Stage Disease
Interventions: BEHAVIORAL: Advance care planning|BEHAVIORAL: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)
Status: RECRUITING
Conditions: Middle Cerebral Artery Acute Ischemic Stroke
Interventions: OTHER: Multimodal MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Simvastatin in Overcoming Chemotherapy Resistance in Patients With Relapsed or Refractory Multiple Myeloma
Status: WITHDRAWN
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Quality-of-Life Assessment|DRUG: Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa
Status: COMPLETED
Conditions: Dengue|Chikungunya|Malaria
Interventions: DIAGNOSTIC_TEST: VIDAS® Dengue Antigen NS1, VIDAS® Anti-Dengue IgM, VIDAS® Anti-Dengue IgG, VIDAS® Anti-Chikungunya IgM and VIDAS® Anti-Chikungunya IgG|OTHER: Standard of care practices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect Alb-PRF & A-PRF in Alveolar Ridge Preservation in Diabetes Patients - A RCCT
Status: NOT_YET_RECRUITING
Conditions: Tooth Extraction Status Nos
Interventions: PROCEDURE: Study Group|PROCEDURE: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: P2 Clinical Efficacy & Safety Study of V-111 Monotherapy & Sacituzumab Govitecan-hziy/V-111 Combo Therapy for mTNBC .
Status: WITHDRAWN
Conditions: Metastatic Triple Negative Breast Cancer
Interventions: DRUG: Sabizabulin|DRUG: Sacituzumab Govitecan-hziy|DRUG: Sabizabulin/Sacituzumab govitecan-hziy Combo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KN046 Combined With Ningatinib in the Treatment of Advanced Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Advanced HCC
Interventions: DRUG: KN046 （PD-L1/CTLA4 BsAb）|DRUG: Ningetinib Tosylate（multi-target TKI）
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept (POC) Study of the Soliton's Acoustic Scar Reduction (ASR) Treatment for the Treatment of Keloid Scar
Status: COMPLETED
Conditions: Keloid Scar
Interventions: DEVICE: Soliton's Acoustic Scar Reduction (SAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Immunochemotherapy and AlloSCT in Patients With High Risk CD33+ AML/MDS
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Gemtuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites
Status: ACTIVE_NOT_RECRUITING
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Motivational Interviewing (MI)|DRUG: Nicotine Replacement Therapy (NRT)|DRUG: Nicotine Lozenge|BEHAVIORAL: Message Framing|OTHER: saliva sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations.
Status: COMPLETED
Conditions: Locally Advanced Solid Tumors|Metastatic Solid Tumors
Interventions: DRUG: Entrectinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of ALXN1840 on the Metabolism of a CYP2B6 Substrate in Healthy Participants
Status: COMPLETED
Conditions: Wilson Disease
Interventions: DRUG: ALXN1840|DRUG: Bupropion Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Stiffening Wire in Colonoscopy With Pre-Owned Colonoscopes
Status: TERMINATED
Conditions: Colonoscopy
Interventions: DEVICE: Colonoscope stiffening device|DEVICE: Colonoscope stiffening device|DEVICE: Colonoscope stiffening device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Induction With Foley OR Misoprostol (INFORM) Study
Status: COMPLETED
Conditions: Pre-eclampsia|Fetus or Newborn; Effects of Induction of Labor
Interventions: DEVICE: Foley Catheter|DRUG: Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Versus Inpatient Percutaneous Nephrolithotomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Calculi
Interventions: PROCEDURE: Ambulatory tubeless PCNL|PROCEDURE: Inpatient PCNL with nephrostomy tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Preanesthetic Dexmedetomidine in Elderly, Treated-hypertensive Patients
Status: COMPLETED
Conditions: Perioperative Care
Interventions: DRUG: Dexmedetomidine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Role of Vitamins E and C in Maintaining Lung Health in People With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DIETARY_SUPPLEMENT: Vitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of C1 Esterase Inhibitor in Hereditary Angioedema Subjects
Status: COMPLETED
Conditions: Hereditary Angioedema
Interventions: DRUG: C1 esterase inhibitor [human] (C1INH-nf)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Valproate Efficacy in Cocaine-Bipolar Comorbidity
Status: COMPLETED
Conditions: Bipolar Disorder|Cocaine Dependence
Interventions: DRUG: Valproate|DRUG: Placebo|DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Investigating the Movement of Lu AG09222 Into, Through, and Out of the Body of Healthy Caucasian, Chinese, and Japanese Participants
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Lu AG09222|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mircera in Renal Anemia Among Filipino Chronic Kidney Disease Patients
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: methoxy polyethylene glycol-epoetin beta [Mircera]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of Endometrium
Interventions: DRUG: Fulvestrant|DRUG: Abemaciclib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Topical SHR0302 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis
Status: ACTIVE_NOT_RECRUITING
Conditions: Atopic Dermatitis
Interventions: DRUG: SHR0302 Ointment|DRUG: SHR0302 Ointment|DRUG: SHR0302 Ointment|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Ablative Radiotherapy for Oligometastatic Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Oligometastasis Hepatocellular Carcinoma
Interventions: RADIATION: Radiation: Stereotactic body radiotherapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 10 Weeks of Age
Status: COMPLETED
Conditions: Infections, Streptococcal|Streptococcus Pneumoniae
Interventions: BIOLOGICAL: Pneumococcal conjugate vaccine GSK1024850A|BIOLOGICAL: Tritanrix-HepB/Hib|BIOLOGICAL: Hiberix|BIOLOGICAL: Tritanrix-HepB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Long vs Extended-short Nail When Treating Proximal Femur Fractures
Status: RECRUITING
Conditions: Hip Fractures
Interventions: DEVICE: TFNA extended-short nail (235 mm)|DEVICE: TFNA long nail (260-480mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Connected Solution of Assistance Dedicated to Caregivers and People With Alzheimer's Disease or Related Diseases
Status: UNKNOWN
Conditions: Alzheimer Disease
Interventions: OTHER: Functionalities of the Lili Smart Solution activated|OTHER: Functionalities of the Lili Smart Solution non activated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Economic Evaluation of Baroreceptor STIMulation for the Treatment of Resistant HyperTensioN
Status: COMPLETED
Conditions: Hypertension
Interventions: DEVICE: Baroreceptor stimulation with Barostim Neo TM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ZIPS Study - Zip Incision aPproximation vs. Suture
Status: COMPLETED
Conditions: Wound|Cardiac Arrhythmia
Interventions: DEVICE: Zip Surgical Skin Closure Device|DEVICE: Standard Suture Closure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Allograft Ridge Augmentation: 3D Analysis of CAD/CAM Custom Milled and Prefabricated Conventional Allogeneic Bone Blocks and Dental Implant Follow-up
Status: ACTIVE_NOT_RECRUITING
Conditions: Alveolar Ridge Augmentation
Interventions: PROCEDURE: Extensive alveolar ridge augmentation with allogeneic bone blocks; dental implant insertion in allogeneic bone graft
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment of Helminth co-Infection: Short-Term Effects on HIV-1 Progression Markers and Immune Activation
Status: COMPLETED
Conditions: HIV Infections|Helminthiasis
Interventions: DRUG: Albendazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Erythropoietin Therapy for Subarachnoid Hemorrhage
Status: COMPLETED
Conditions: Aneurysmal Subarachnoid Hemorrhage
Interventions: DRUG: erythropoietin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Namodenoson in the Treatment of Non-Alcoholic Steatohepatitis (NASH)
Status: RECRUITING
Conditions: NASH - Nonalcoholic Steatohepatitis
Interventions: DRUG: Namodenoson|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nifedipine Versus Hydralazine in Management of Severe Hypertension in Pregnancy
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Hydralazine|DRUG: Nifedipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Morphine Versus Methadone As First Line Strong Opioid for Cancer Pain
Status: TERMINATED
Conditions: Advanced Cancer|Solid Tumors
Interventions: DRUG: Morphine|DRUG: Methadone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Status: COMPLETED
Conditions: Surgery
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen 600 mg|DRUG: Oxycodone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-NY104 PET/CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses
Status: RECRUITING
Conditions: Clear Cell Renal Cell Carcinoma
Interventions: DIAGNOSTIC_TEST: 68Ga-NY104 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of 4-Demethylcholesteryloxycarbonylpenclomedine (DM-CHOC-PEN) in Patients With Advanced Cancer"
Status: COMPLETED
Conditions: Advanced Cancer
Interventions: DRUG: DM-CHOC-PEN
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Viral Kinetics of SARS-CoV-2 in Patients With COVID-19 in the Intensive Care Unit Undergoing Dental Procedures
Status: RECRUITING
Conditions: SARS-CoV2 Infection|Viral Load|Oral Diseases|Dental Treatment
Interventions: OTHER: Non-bloody dental procedures (control group)|PROCEDURE: Bloody dental procedures (study group)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Constraint-Induced Therapy Modified for Rehabilitating Arm Function in Stroke Survivors w/Plegic Hands
Status: COMPLETED
Conditions: Chronic Stroke Survivors With Plegic Hand
Interventions: BEHAVIORAL: Constraint-Induced Movement (CI) Therapy|BEHAVIORAL: Stretching, Relaxation, & Biofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Strategy of Ankle Fracture Combined With Deltoid Ligament Rupture
Status: UNKNOWN
Conditions: Ankle Fractures
Interventions: PROCEDURE: repair of deltoid ligament
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Interventions: DIETARY_SUPPLEMENT: Vitamin D (cholecalciferol)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of IV Acetaminophen in the Treatment of Post Operative Pain in Patients Undergoing Craniotomy and Spine Surgery
Status: UNKNOWN
Conditions: Postoperative Pain
Interventions: DRUG: Acetaminophen or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Tigecycline and Vancomycin With Aztreonam in Complicated Skin and Skin Structure Infections
Status: COMPLETED
Conditions: Skin Diseases, Infectious
Interventions: DRUG: Tigecycline|DRUG: vancomycin with aztreonam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Study to Assess the Utility of CA-4F in a Canadian Cardiology Setting
Status: UNKNOWN
Conditions: Transthyretin Amyloid Cardiomyopathy ("ATTR-CM")
Interventions: DEVICE: CA-4F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Study of LY2963016 Compared to Lantus® in Adult Chinese Participants With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: LY2963016|DRUG: Lantus®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal Cancer
Status: TERMINATED
Conditions: Cancer|Ovarian|Relapse|Chemotherapy
Interventions: DRUG: TOPOTECAN|DRUG: LAPATINIB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT