pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Evaluate the Efficacy, Safety and Tolerability of a Non-hormonal Intravaginal Gel in Postmenopausal Women With Symptoms of Vaginal Dryness.
Status: UNKNOWN
Conditions: Vaginal Atrophy
Interventions: DRUG: Hidra1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dutch National Randomized Study: PSMA-PET/CT as a Triage Tool for Pelvic Lymph Node Dissection in Prostatectomy Patients
Status: RECRUITING
Conditions: Prostate Cancer Metastatic|Prostate Cancer|Lymph Node Metastases
Interventions: DEVICE: PSMA-PET/CT|OTHER: Nomogram
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: ASk Questions in GYnecologic Oncology (ASQ-GYO)
Status: RECRUITING
Conditions: Ovarian Cancer|Endometrial Cancer|Cervical Cancer|Vulvar Cancer|Vaginal Cancer|Gestational Trophoblastic Disease
Interventions: BEHAVIORAL: Administration of the ASk Questions in GYnecologic Oncology (ASQ-GYO) Question Prompt List
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: ADMIRAL Trial: Adaptive Mediastinal Radiation With Chemo-Immunotherapy
Status: TERMINATED
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8
Interventions: DRUG: Cisplatin|BIOLOGICAL: Durvalumab|DRUG: Etoposide|RADIATION: Hypofractionated Radiation Therapy|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants
Status: COMPLETED
Conditions: Premature Infant Disease|Family Research|Parent-Child Relations|Self Efficacy|Patient Engagement|Patient Empowerment|Parenting|Chronic Conditions, Multiple
Interventions: BEHAVIORAL: PREEMIE PROGRESS|BEHAVIORAL: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study Evaluating MAC-321 in Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Neoplasms|Colonic Neoplasms|Rectal Neoplasms
Interventions: DRUG: MAC-321
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Active Powered Prosthesis (APEX) for Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: DEVICE: Active Powered Prosthesis (APEX) for Spinal Cord Injury
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Examining the Feasibility of Implementation, Patterns of Association, and Outcomes in HRV Biofeedback (HRVB) Intervention and Music Listening Control (MLC) on Alzheimer's Disease (AD) Family Caregivers (FCGs) Public Title: Caring Relationship Expression Study
Status: UNKNOWN
Conditions: Alzheimer's Disease and Related Dementias Family Caregivers
Interventions: BEHAVIORAL: Music Listening Control (MLC)|BEHAVIORAL: Heart Focused Breathing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Positive Psychology Intervention for Hematopoietic Stem Cell Transplantation Survivors
Status: NOT_YET_RECRUITING
Conditions: Hematopoietic Stem Cell Transplant
Interventions: BEHAVIORAL: PATH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 8-Week Study of Tolvaptan Dose Forms in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Status: COMPLETED
Conditions: Autosomal Dominant Polycystic Kidney Disease
Interventions: DRUG: Tolvaptan MR|DRUG: Tolvaptan IR|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Amniotic Membrane Injectable in the Treatment of Recalcitrant Plantar Fasciitis
Status: COMPLETED
Conditions: Plantar Fasciitis
Interventions: OTHER: Marcaine|OTHER: 0.5cc AmnioFix|OTHER: 1.25cc AmnioFix|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: mRNA-1273|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fall Risk Reduction in Multiple Sclerosis: Exercise Versus Behavior
Status: COMPLETED
Conditions: Multiple Sclerosis|Adult Disease
Interventions: BEHAVIORAL: Home-based exercise|BEHAVIORAL: Education|BEHAVIORAL: Exercise plus Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ButCoIns - Metabolic Effects of Resistent Starch and Arabinoxylans in Subjects With Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Healthy Carbohydrate Diet vs. Western Style Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Comparison of Safety, Tolerability and Immunogenicity of Influenza Vaccines in Adults and Elderly
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Cell culture derived influenza vaccine|BIOLOGICAL: egg-derived influenza subunit vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PACT Programme for Parents of Children With SHCN
Status: RECRUITING
Conditions: Urologic Diseases|Gastrointestinal Diseases|Vascular Diseases|Cleft Lip and Palate|Neurodevelopmental Disorders|Attention Deficit Hyperactivity Disorder|Autism Spectrum Disorder|Developmental Delay
Interventions: BEHAVIORAL: Prosocial-orientated Acceptance and Commitment Training plus positive parenting advice|BEHAVIORAL: Positive parenting advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias
Status: NOT_YET_RECRUITING
Conditions: Refractory Acute Leukemia|Pediatric Relapsed
Interventions: DRUG: Ziftomenib|DRUG: Venetoclax|DRUG: Azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Lung Inflammation Model in Healthy Volunteers by Radiological Tools and Glucocorticoid Treatment
Status: COMPLETED
Conditions: Experimental Lung Inflammation
Interventions: DRUG: Dexamethasone|DRUG: Sterile isotonic saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease
Status: TERMINATED
Conditions: Autoimmune Diseases|Non-small Cell Lung Cancer|Rheumatoid Arthritis|Psoriasis|Giant Cell Arteritis|Polymyalgia Rheumatica|Systemic Lupus Erythematosus|Crohn Disease|Multiple Sclerosis|Ulcerative Colitis
Interventions: DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of ASI on Sensory, Motor, Cognitive, Behavioral Skills and Social Participation in Children With ADHD
Status: RECRUITING
Conditions: Attention Deficit Disorder With Hyperactivity|Sensory Integration Disorder|Motor Activity|Cognitive Deficit in Attention|Behavior Hyperactive|Emotional Regulation|Social Skills
Interventions: BEHAVIORAL: Ayres Sensory Integration Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect Of Menstrual Cycle On Vaginal Blood Flow In Pre-Menopausal Healthy Women.
Status: COMPLETED
Conditions: Sexual Dysfunction, Physiological
Interventions: DEVICE: Vaginal Heat Wash-Out Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of the Picosure 755nm Alexandrite Laser With Lens Array for the Treatment of Acne Scars
Status: COMPLETED
Conditions: Acne Scars
Interventions: DEVICE: 755nm Alexandrite laser with lens array
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study in Healthy People to Compare How 2 Different High Dose Formulations of BI 1015550 Are Taken up in the Body
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: BI 1015550 Formulation C2|DRUG: BI 1015550 Formulation C1 (R) then BI 1015550 Formulation C2 (T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Trial of Intravenous Iron in Combination With Standard of Care Immunotherapy in Melanoma
Status: NOT_YET_RECRUITING
Conditions: Anemia, Iron Deficiency|Melanoma
Interventions: DRUG: Iron dextran 1000 mg IV
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorders
Status: COMPLETED
Conditions: Macular Degeneration|Retinal Vein Occlusion
Interventions: DRUG: Triamcinolone Acetonide (TAC-PF)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Community-based Intervention Among Active Drug Users in Montpellier
Status: COMPLETED
Conditions: Drug Use|HCV Infection
Interventions: DIAGNOSTIC_TEST: HCV screening|DIAGNOSTIC_TEST: Diagnosis of hepatitis C|DRUG: HCV treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: A Randomized Controlled Trial of LOT-CRT Versus conventionaL BiVP in Heart Failure Patients With NICD
Status: RECRUITING
Conditions: Heart Failure|Intraventricular Block
Interventions: PROCEDURE: LOT-CRT group|PROCEDURE: BiVP group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Peri-calcification Edema in Neurocysticercosis (NCC)
Status: TERMINATED
Conditions: Neurocysticercosis
Interventions: DRUG: Acetazolamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Evaluation of [11C]MPC6827
Status: RECRUITING
Conditions: Neurodegenerative Diseases|Alzheimer Disease|Amyotrophic Lateral Sclerosis
Interventions: DRUG: [11C]MPC6827
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Microvascular Dysfunction Assessment to Predict Left Ventricular Reverse Remodeling
Status: RECRUITING
Conditions: Heart Failure|Left Ventricular Dysfunction|Idiopathic Dilated Cardiomyopathy
Interventions: DIAGNOSTIC_TEST: Thermodilution based assessment of coronary microcirculation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training
Status: RECRUITING
Conditions: Schizophrenia|Neuronal Plasticity|Exercise
Interventions: PROCEDURE: Aerobic Endurance Training|PROCEDURE: Flexibility, strengthening and balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pembrolizumab (MK-3475) Plus Docetaxel Versus Placebo Plus Docetaxel in Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-921/KEYNOTE-921)-China Extension
Status: TERMINATED
Conditions: Prostatic Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Docetaxel|DRUG: Prednisone|DRUG: Placebo|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Ultrasound Microbubble Contrast-Enhanced (CEUS) Sentinel Lymph Node Imaging With Guided Biopsy in Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Perflutren Protein-Type A Microspheres Injectable Suspension|DEVICE: Contrast-Enhanced Ultrasound (CEUS)|PROCEDURE: Biopsy + Radioactive Seed Placement|BEHAVIORAL: Phone Call
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain
Status: COMPLETED
Conditions: Spinal Cord Diseases|Spinal Cord Injuries|Neuralgia|Pain
Interventions: DRUG: pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drotaverine to Shorten the Length of Labor
Status: COMPLETED
Conditions: Prolonged First Stage of Labor|Failure of Cervical Dilation as Antepartum Condition|Labor Pain|Mild Birth Asphyxia, APGAR 4-7
Interventions: DRUG: Drotaverine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Duration Ultrasound for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee
Interventions: DEVICE: Long duration ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of SYNC-T - Immunotherapy for Advanced/Metastatic Castration-Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Castration-resistant Prostate Cancer
Interventions: DRUG: SV-102
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Home Sampling Versus Conventional Sampling for Screening of Urogenital Chlamydia Trachomatis in Young Men and Women.
Status: COMPLETED
Conditions: Chlamydia Trachomatis|Mass Screening
Interventions: PROCEDURE: Home sampling (urine test) for uro-genital C.trachomatis.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study on Sequential Immunization of Inactivated COVID-19 Vaccine and Recombinant COVID-19 Vaccine (Ad5 Vector) in Elderly Adults
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Ad5 vectored vaccine|BIOLOGICAL: Inactive SARS-CoV-2 vaccine (Vero cell)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of [177Lu]Lu-PSMA-137 In Metastatic Castrate Resistant Prostate Cancer（mCRPC）
Status: NOT_YET_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: [177Lu]Lu-PSMA-137
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol and Dexmedetomidine on Inflammation
Status: UNKNOWN
Conditions: Inflammation|Postoperative Delirium|Anesthesia
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Positive Airway Pressure (CPAP) After Adenotonsillectomy in Children
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Sleep Apnea Syndromes|Child Behavior Disorders|Attention Deficit Disorder With Hyperactivity|Disorders of Excessive Somnolence
Interventions: PROCEDURE: CPAP treatment|OTHER: No CPAP treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capecitabine Versus Vinorelbine in High Risk Breast Cancer With Pathologic Residual Tumors After Preoperative Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Pathologic Residual Cancer Cells
Interventions: DRUG: Capecitabine, Oral, 500 Mg|DRUG: Vinorelbine Tartrate Oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Flash Continuous Glucose Monitoring to Reduce Hyperglycemia in People With T2 Diabetes
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2
Interventions: DEVICE: FreeStyle Libre System|DEVICE: FreeStyle Libre System plus food app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy and Safety of 90Y Microsphere Combined With FOLFIRI and Bevacizumab in Second-line Treatment of CRLM
Status: RECRUITING
Conditions: Colorectal Cancer Metastatic
Interventions: DRUG: SIRT with Yttrium-90 Microspheres|DRUG: FOLFIRI and Bevacizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Trial With Two New Tooth-colored Restorative Materials in Class I/II Cavities
Status: ACTIVE_NOT_RECRUITING
Conditions: Caries|Defective Restorations
Interventions: DEVICE: Alcasite restorative material|DEVICE: Bulk fill glass hybrid restorative material
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Osteoarthritis Pain of the Knee
Status: COMPLETED
Conditions: Osteoarthritis Pain of the Knee
Interventions: DRUG: Diclofenac sodium active topical patch|DRUG: Placebo patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Feasibility of Transulnar Artery Approach for Coronary Angiography or Angioplasty
Status: UNKNOWN
Conditions: Intervention|Transulnar|Transradial
Interventions: PROCEDURE: transulnar approach interventional procedure|PROCEDURE: transradial approach interventional procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The ARCAN Database is Used for Retrospective Non-interventional Research Projects. The Database Collects Clinical and Laboratory Data From Patients With Lymphoid Malignancies. The Database Doesn't Require Biological Sample of Patients, it Records Only Information Based on the Patients' Medical File.
Status: RECRUITING
Conditions: Hematologic Diseases
Interventions: OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: ED50 and ED95 of Intranasal Dexmedetomidine in Pediatric Patients Undergoing Transthoracic Echocardiography Study
Status: COMPLETED
Conditions: Patients for Transthoracic Echocardiography|Unknown Diagnosis
Interventions: DRUG: intranasal dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Therapy for Locally Advanced Rectal Cancer With Fruquintinib, Toripalimab and SRT
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: Fruquintinib|DRUG: Toripalimab|RADIATION: Short-course radiotherapy|PROCEDURE: TME
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Paroxetine Hydrochloride Controlled-Release Tablets 25 mg|DRUG: Paxil CR™ Tablets 25 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Phase III Clinical Trial of Quadrivalent Influenza Vaccine in Healthy Subjects Aged 6 to 35 Months
Status: RECRUITING
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: Quadrivalent influenza vaccine(0.25ml)|BIOLOGICAL: Quadrivalent influenza vaccine(0.5ml)|BIOLOGICAL: Trivalent influenza vaccine(BV)|BIOLOGICAL: Trivalent influenza vaccine(BY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Umbilical Cord Mesenchymal Stem Cells Infusion Via Hepatic Artery in Cirrhosis Patients
Status: UNKNOWN
Conditions: Liver Cirrhosis|Radiology|Mesenchymal Stem Cells|Umbilical Cord
Interventions: BIOLOGICAL: umbilical cord Mesenchymal Stem Cells|DRUG: Conserved therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CAPER Trial: A Phase Ib Clinical Trial of Cyclophosphamide And PEmbrolizumab in Metastatic Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: DRUG: Cyclophosphamide 50mg|DRUG: Pembrolizumab 25 mg/1 ML Intravenous Solution [KEYTRUDA]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Status: COMPLETED
Conditions: Respiration, Artificial|Critical Illness|Chronic Disease|Exercise Therapy|Rehabilitation|Physical Therapy Modalities
Interventions: OTHER: multimodal physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Functional Electrical Stimulation in Gluteus Medius in Rehabilitation After Total Hip Arthroplasty
Status: COMPLETED
Conditions: OSTEOARTHRITIS
Interventions: PROCEDURE: PPTHA|PROCEDURE: FES and PPTHA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Angong Niuhuang Wan for Stroke
Status: UNKNOWN
Conditions: Stroke (CVA) or TIA
Interventions: DRUG: Angong Niuhuang Wan|DRUG: Angong Niuhuang Wan Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise and NutraStem (NT-020): Effects on Stem Cells
Status: COMPLETED
Conditions: Adult Stem Cell Proliferation
Interventions: DRUG: NutraStem|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations
Status: TERMINATED
Conditions: Glioma|High Grade Glioma|Pontine Tumors
Interventions: DRUG: Dasatinib|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 755nm Alex Laser for Treatment of Pigmented and Vascular Lesions and Scars
Status: COMPLETED
Conditions: Benign Pigmented and Vascular Lesions and Scars
Interventions: DEVICE: 755nm Alex laser
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Potential Role of Sirtuins as Epigenetic Biomarkers of the Patient With Atherosclerosis or Calcific Aortic Stenosis
Status: RECRUITING
Conditions: Atherosclerosis and Calcific Aortic Stenosis With and Without Diabetes
Interventions: DIAGNOSTIC_TEST: lncRNA signature analyses
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase II, Parallel Group, Randomized, Placebo-Controlled Study of the Safety and Efficacy of Thalidomide in Reducing Weight Loss in Adults With HIV Wasting Syndrome
Status: COMPLETED
Conditions: HIV Infections|HIV Wasting Syndrome
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: External Counterpulsation Therapy for Severe Steno-occlusive Intracranial Stenosis
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DEVICE: Enhance External Counterpulsation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cannabis Consumption on Sperm Nuclear Quality in Infertile Men
Status: UNKNOWN
Conditions: Teratozoospermia
Interventions: BEHAVIORAL: Questionnaire about cannabis consumption|PROCEDURE: blood intake|PROCEDURE: Semen samples collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy, Safety and Immunogenicity of Takeda's Tetravalent Dengue Vaccine (TDV) in Healthy Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Placebo|BIOLOGICAL: Tetravalent Dengue Vaccine (TDV)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Active-Controlled Extension Study to NCT01155466 [P04938] and NCT01227265 [P07037] (P06153)
Status: TERMINATED
Conditions: Parkinson Disease|Idiopathic Parkinson Disease
Interventions: DRUG: Preladenant|DRUG: Rasagiline|DRUG: Placebo to preladenant|DRUG: Placebo to rasagiline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability and Efficacy of a Liproca® Depot Injection in Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: 2-Hydroxyflutamide Depot
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Mendelian Reverse Cholesterol Transport Study
Status: SUSPENDED
Conditions: Cholesterol, HDL|Lipid Metabolism, Inborn Errors|Tangier Disease|LCAT Deficiency|Cholesteryl Ester Transfer Protein (CETP) Deficiency
Interventions: DRUG: 3H-cholesterol bound to albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Azacytidine Plus CAOLD Regimen in Relapsed/Refractory Angioimmunoblastic T Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed Angioimmunoblastic T-Cell Lymphoma|Refractory Angioimmunoblastic T-cell Lymphoma
Interventions: DRUG: Azacytidine plus CAOLD regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Autologous Bone Marrow Transplant for Children With Acute Myelogenous Leukemia (AML) in First Complete Remission
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Galantamine Used to Treat Patients With Mild to Moderate Alzheimer's Disease
Status: TERMINATED
Conditions: Alzheimer's Disease
Interventions: DRUG: Galantamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LDE225 in Treating Patients With Stage II-III Estrogen Receptor- and HER2-Negative Breast Cancer
Status: WITHDRAWN
Conditions: Breast Neoplasms
Interventions: DRUG: Erismodegib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Rohto (r) Hydra|DRUG: Systane (r) Ultra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: FUnctional diagnoSIs of corONary Stenosis (FUSION)
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Stenosis
Interventions: PROCEDURE: ICA (Invasive Coronary Angiography)|PROCEDURE: OCT|PROCEDURE: FFR|OTHER: VFR Analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients
Status: RECRUITING
Conditions: Total Shoulder Arthroplasty|Reverse Total Shoulder Arthroplasty
Interventions: DRUG: Liposomal bupivacaine|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: REJOIN Trial for Older Breast Cancer Survivors
Status: RECRUITING
Conditions: Breast Cancer Female
Interventions: BEHAVIORAL: Relieving Joint Pain and Improving AI Adherence in Older Breast Cancer Survivors (REJOIN)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
Status: RECRUITING
Conditions: Chronic Kidney Diseases|End Stage Renal Disease|Arteriovenous Fistula|Hemodialysis Access Failure|ESRD|Vascular Access Complication|Renal Failure|Catheter Complications|Catheter Dysfunction|Renal Insufficiency
Interventions: DEVICE: SelfWrap Bioabsorbable Perivascular Wrap|PROCEDURE: Untreated AVF Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Ezetimibe + Statin (simvastatin, atorvastatin, or pravastatin)|DRUG: Double Statin (simvastatin, atorvastatin, or pravastatin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The TMC125-C214 Study Provides Early Access to TMC125 for HIV-1 Infected Patients Who Have Failed Multiple Antiretroviral Regimens and Will Also Gather Information on the Long-term Safety and Tolerability of TMC125 Combined With Other Antiretroviral Drugs
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: TMC125
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment
Status: TERMINATED
Conditions: Liver Cirrhosis, Biliary
Interventions: DRUG: Obeticholic Acid (OCA)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of a New Treatment in Vitrectomized Subjects With Diabetic Macular Edema
Status: COMPLETED
Conditions: Diabetic Macular Edema|Vitrectomy
Interventions: DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietary Nitrate Supplementation and Crossfit Athletes
Status: COMPLETED
Conditions: Performance
Interventions: DIETARY_SUPPLEMENT: Dietary Nitrate|DIETARY_SUPPLEMENT: Potassium Chloride (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment
Status: COMPLETED
Conditions: Peri-implantitis|Periodontal Diseases
Interventions: DRUG: amoxicillin 500 mg + metronidazole 500 mg|PROCEDURE: non-surgical periodontal and peri-implant treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antipsychotic Effects on Brain Function in Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder
Interventions: DRUG: Aripiprazole|DRUG: Risperidone|DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Astra Zeneca (Immuno Stereotactic Ablative Body Radiotherapy) ISABR Study: Randomized Phase I/II Study of Stereotactic Body Radiotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Durvalumab (MEDI 4736)|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease
Status: RECRUITING
Conditions: Chronic Graft Versus Host Disease
Interventions: DRUG: Belumosudil|PROCEDURE: Biospecimen Collection|OTHER: Electronic Health Record Review|DRUG: Placebo Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry Eye
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: NGF|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel 68Ga Labeled FAP Ligand PET/CT in Patients With Various Malignant Tumors
Status: RECRUITING
Conditions: Cancer|Malignant Neoplasm|Tumors|Metastatic Cancer
Interventions: DIAGNOSTIC_TEST: 68Ga-DOTA-GPFAPI-04 PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Ketone Ester Supplementation on Hypoxic Tolerance
Status: COMPLETED
Conditions: Ketosis|Hypoxia
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Heat-treated Postbiotic Consumption in Healthy People With Mild to Moderate Gastrointestinal Symptoms
Status: COMPLETED
Conditions: Healthy|Gastrointestinal Dysfunction
Interventions: DIETARY_SUPPLEMENT: Heat treated postbiotic Bifidobacterium Longum consumption|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intra-Operative Adductor Canal Blocks
Status: RECRUITING
Conditions: Knee Osteoarthritis|Knee Arthritis|Knee Pain Chronic|Anesthesia
Interventions: PROCEDURE: aACB|PROCEDURE: sACB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Nevirapine on HCV Viral Load
Status: UNKNOWN
Conditions: HCV Infection.|HCV Viral Load.
Interventions: DRUG: Nevirapine|DRUG: efavirenz, protease inhibitors
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study of Colchicine to Prevent the Postpericardiotomy Syndrome
Status: COMPLETED
Conditions: Postpericardiotomy Syndrome
Interventions: DRUG: Colchicine (for 1 month)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Targeted Phantom Motor Execution on Phantom Limb Control
Status: COMPLETED
Conditions: Phantom Limb|Motor Activity|Amputation Stump|Amputation
Interventions: OTHER: Targeted phantom limb motor execution (exercise)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy of Sodium Oxybate (Xyrem®) in Treatment of Post-traumatic Narcolepsy and Post-traumatic Hypersomnia
Status: WITHDRAWN
Conditions: Hypersomnia|Narcolepsy|Traumatic Brain Injury
Interventions: DRUG: Sodium Oxybate Oral Solution [Xyrem]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study
Status: COMPLETED
Conditions: Angioplasty|Chronic Coronary Occlusion|Stent Thrombosis|Vascular Disease|Myocardial Ischemia|Coronary Artery Stenosis|Coronary Disease|Coronary Artery Disease|Coronary Restenosis
Interventions: DEVICE: XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Intraoperative Slow-release Dexamethasone Implant for Epiretinal Membrane
Status: UNKNOWN
Conditions: Epiretinal Membrane
Interventions: PROCEDURE: slow-release dexamethasone implant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female Patients
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Arthritic Psoriasis|Psoriasis|Inflammatory Bowel Diseases
Interventions: DRUG: BMS-986165|DRUG: Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 μg ethinyl estradiol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Low FODMAPs Diet in Celiac Patients With Persistent Gastrointestinal Symptoms
Status: UNKNOWN
Conditions: Celiac Disease
Interventions: DIETARY_SUPPLEMENT: Balanced low FODMAPs /gluten free diet|DIETARY_SUPPLEMENT: Balanced gluten free diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Non-surgical Periodontal Therapy on Cardiovascular Risk
Status: NOT_YET_RECRUITING
Conditions: Cardiovascular Diseases|Periodontitis
Interventions: PROCEDURE: Non-surgical periodontal therapy|PROCEDURE: Control periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Bortezomib With Steroid Pulse Therapy for Acute Cellular Rejection in Kidney Transplantation
Status: UNKNOWN
Conditions: Kidney Transplantation
Interventions: DRUG: Bortezomib|DRUG: Steroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Cirrhosis
Interventions: BIOLOGICAL: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Indicator Amino Acid Oxidation in ICU Patients
Status: RECRUITING
Conditions: Critical Illness|Muscle Wasting
Interventions: COMBINATION_PRODUCT: Standard protein enteral nutrition with enteral tracer|COMBINATION_PRODUCT: High protein enteral nutrition with enteral tracer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Duloxetine in the Treatment of Stress Urinary Incontinence(Uncontrolled Leakage of Urine)
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: DRUG: duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Reducing Recurrence of Symptomatic Atrial Fibrillation After Catheter Ablation by App-based Mental Training
Status: COMPLETED
Conditions: Paroxysmal Atrial Fibrillation|Persistent Atrial Fibrillation|Meditation
Interventions: OTHER: Mental training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: N-acetyl-cysteine and Carbohydrate Metabolism Disorder in Obese Women
Status: UNKNOWN
Conditions: Insulin Resistance|Obesity|Carbohydrate Metabolism Disorder
Interventions: DIETARY_SUPPLEMENT: NAC group|DIETARY_SUPPLEMENT: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy With Depigmented and Polymerized Allergen Extract of Phleum Pratense
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Conjunctivitis, Allergic|Asthma
Interventions: BIOLOGICAL: Immunotherapy with modified extract of P. pratense pollen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Technology to Optimize Hypertension Treatment in Elderly People in Primary Care
Status: COMPLETED
Conditions: Systemic Arterial Hypertension|Pharmacotherapy|Pharmaceutical Care
Interventions: OTHER: MRPA procedure|OTHER: Pharmaceutical intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Laser Power and Fiber Traction Speed on the Outcomes of Endovenous Laser Ablation
Status: COMPLETED
Conditions: Varicose Veins
Interventions: PROCEDURE: Endovenous laser ablation (EVLA)|DEVICE: Laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Wireless Stimulation Endocardially for Cardiac Resynchronization Therapy
Status: COMPLETED
Conditions: Heart Failure|Ventricular Dysfunction|Cardiomyopathy
Interventions: DEVICE: Wireless cardiac stimulator implant to pace the left ventricle for CRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Aripiprazole in the Treatment of Pervasive Developmental Disorders
Status: COMPLETED
Conditions: Pervasive Developmental Disorder
Interventions: DRUG: Aripiprazole oral product|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Injectable POLY-L-Lactic Acid for Treatment of Hill and Valley Acne Scarring
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DEVICE: Sculptra (Poly-L-Lactic Acid Dermal Implant)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxorubicin By Infusion or Chemoembolization in Treating Patients With Advanced Unresectable Hepatocellular Carcinoma (Liver Cancer)
Status: UNKNOWN
Conditions: Liver Cancer
Interventions: DRUG: doxorubicin hydrochloride|PROCEDURE: hepatic artery embolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Melatonin In Reduction of Chemotherapy-Induced Toxicity (MIRCIT) Trial
Status: COMPLETED
Conditions: Advanced Stage Cancer
Interventions: DRUG: 10 mg Melatonin|DRUG: 20 mg Melatonin|DRUG: Matched placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy
Status: UNKNOWN
Conditions: Ventricular Tachycardia|Ischemic Cardiomyopathy|Reduced LVEF
Interventions: PROCEDURE: VT ablation|OTHER: medication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study in Healthy Male Volunteers to Test How the Test Medicine GLPG1972 is Taken up by the Body When Given by Mouth and Into the Vein as an Injection
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: GLPG1972 film-coated tablets|DRUG: [14C]-GLPG1972 solution for infusion|DRUG: [14C]-GLPG1972 oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE