pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Tissue Distribution of F18-FDG Labeled ABMSCT in Patients With Type2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Non-Insulin-Dependent
Interventions: PROCEDURE: stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Impact of Silymarin Adjunct Therapy on Proteinuria in Type 2 Diabetic Patients on RAS Inhibitors
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Silymarin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study of Colchicine and Theophylline
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Theophylline|DRUG: Colchicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: COLLISION RELAPSE Trial
Status: RECRUITING
Conditions: Colorectal Cancer|Liver Metastases|Liver Metastasis Colon Cancer|Chemotherapy Effect|Surgery|Recurrence
Interventions: DRUG: Neoadjuvant systemic therapy (CAPOX+/-B FOLFOX+/-B FOLFIRI+/-B)|OTHER: Repeat local treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of BG00011 in Participants With Idiopathic Pulmonary Fibrosis
Status: TERMINATED
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: BG00011|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: BIBF 1120 + Carboplatin/Pegylated Liposomal Doxorubicin (PLD) in Patients With Advanced Ovarian Cancer, Fallopian Tube Carcinoma or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms|Peritoneal Neoplasms
Interventions: DRUG: BIBF 1120 + PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min|DRUG: BIBF 1120+ PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min|DRUG: BIBF 1120 + PLD 30 mg/m2 + CBDCA AUC5 mg/mL*min
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Alisertib With and Without Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue|Nodal Marginal Zone B-cell Lymphoma|Recurrent Adult Burkitt Lymphoma|Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma|Recurrent Marginal Zone Lymphoma|Splenic Marginal Zone Lymphoma|Waldenström Macroglobulinemia
Interventions: DRUG: alisertib|BIOLOGICAL: rituximab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gamma Tocopherol Enriched Supplementation on Response to Inhaled LPS
Status: COMPLETED
Conditions: Mild, Allergic Asthma
Interventions: DRUG: Gamma Tocopherol 700 mg capsules,|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Knee Functionality Recovery Indicators in Athletes Submitted to Ligamentoplasty of the Anterior Cruciate Ligament
Status: RECRUITING
Conditions: Ligament Injury|Ligament Rupture|Ligament Disorders
Interventions: DIAGNOSTIC_TEST: Diagnostic test through functional tests and comparison of scales applied to participants in the pre-surgical and post-surgical period.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain and Suction Curettage
Status: COMPLETED
Conditions: Curettage|Analgesia|Paracervical Block|Paracetamol
Interventions: DRUG: paracetamol|DRUG: dexketoprofen trometamol|DRUG: suction curettage|DRUG: suction curettage|OTHER: without drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Ascending Single Doses of Surotomycin in Healthy Participants (MK-4261-008)
Status: COMPLETED
Conditions: Clostridium Difficile Associated Diarrhea (CDAD)
Interventions: DRUG: Surotomycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2|Cholesterolemia
Interventions: DRUG: Bempedoic acid + Ezetimibe FDC Oral Tablet|DRUG: Ezetimibe 10 mg Oral Tablet|DRUG: Placebo Oral Tablet|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Anti-aging Efficacy of Marine Collagen Peptides
Status: RECRUITING
Conditions: Skin Condition|Hair Fragility|Nails, Ingrown
Interventions: DIETARY_SUPPLEMENT: Marine Collagen Peptides|DIETARY_SUPPLEMENT: placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Camrelizumab in Combination With Apatinib in Advanced ICC: A Single-arm Phase II Study
Status: RECRUITING
Conditions: Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Camrelizumab|DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
Status: RECRUITING
Conditions: Oncology|Breast Cancer|Prostate Cancer|Gynecologic Cancer|Brain Tumor|Brain Cancer|Gynecologic Tumor|Prostate Tumor|Prostate Neoplasm|Breast Tumor|Radiation Toxicity|Quality of Life|Rectal Cancer|Rectal Tumor|Rectal Neoplasms|Lung Cancer|Lung Tumor|Lung Neoplasm|Esophageal Cancer|Esophagus Cancer|Esophageal Tumor|Esophageal Neoplasm|Esophagus Tumor|Esophagus Neoplasm|Pancreatic Cancer|Pancreatic Tumor|Pancreatic Neoplasms|Head and Neck Cancer|Head and Neck Neoplasms|Head and Neck Tumor|Tumor|Neoplasms|Bladder Cancer|Bladder Neoplasm|Liver Cancer|Liver Neoplasms|Liver Metastases|Oligometastases
Interventions: RADIATION: Radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons
Status: COMPLETED
Conditions: HIV Infections|Herpes Simplex|Sexually Transmitted Diseases
Interventions: DRUG: Valacyclovir|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Laparoscopic vs Ultrasound-Guided Transversus Abdominis Plane Block vs Laparoscopic Intraperitoneal Instillation of Local Anesthetic in Pediatrics
Status: COMPLETED
Conditions: Laparoscopic|Ultrasound|Transversus Abdominis Plane Block|Laparoscopic Intraperitoneal Instillation|Pediatrics|Inguinal Hernia Repair
Interventions: PROCEDURE: Ultrasound-guided transversus abdominis plane block|PROCEDURE: Laparoscopic-assisted transversus abdominis plane block|PROCEDURE: Laparoscopic-assisted intraperitoneal instillation|DRUG: Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination
Status: WITHDRAWN
Conditions: Brain Death|Anoxic Brain Injury|Cardiac Arrest|Sedative Intoxication|Narcotic Intoxication
Interventions: DRUG: Flumazenil|DRUG: Naloxone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Relaxation Music to Lower Heart Rate Prior to Cardiac CT
Status: COMPLETED
Conditions: Coronary Artery Disease and Cardiac Anatomy|Patients Undergoing Coronary CT Angiogram|Patients Undergoing CT Pulmonary Vein Angiogram|Patients Undergoing CT Calcium Score
Interventions: OTHER: Relaxation Music
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Amantadine as Adjunctive Therapy to Antipsychotics in Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Amantadine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: peficitinib|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Sodium Butyrate For Improving Cognitive Function In Schizophrenia
Status: WITHDRAWN
Conditions: Schizophrenic Disorders|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Sodium Butyrate|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric Varices
Status: UNKNOWN
Conditions: Liver Cirrhoses|Portal Hypertension|Gastric Varix
Interventions: DRUG: Propranolol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Novel App-based Migraine Treatment Platform - a Pilot Study
Status: TERMINATED
Conditions: Migraine Disorders
Interventions: BEHAVIORAL: Biofeedback training via app on smartphone|BEHAVIORAL: Sham-biofeedback training via app on smartphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Pectoralis (PECS2) Block Versus Intrathecal Morphine
Status: RECRUITING
Conditions: Post-operative Pain
Interventions: PROCEDURE: intrathecal morphine injection|PROCEDURE: ultrasound guided PECS2 block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cabozantinib S-malate in Treating Patients With Relapsed Osteosarcoma or Ewing Sarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Ewing Sarcoma|Metastatic Osteosarcoma|Recurrent Ewing Sarcoma|Recurrent Osteosarcoma|Stage III Osteosarcoma AJCC v7|Stage IV Osteosarcoma AJCC v7|Stage IVA Osteosarcoma AJCC v7|Stage IVB Osteosarcoma AJCC v7|Unresectable Ewing Sarcoma|Unresectable Osteosarcoma
Interventions: DRUG: Cabozantinib S-malate|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Evaluation of Recombinant Hirudin in Prophylaxis of Post-Operative Deep Vein Thrombosis
Status: RECRUITING
Conditions: Prophylaxis of Deep Vein Thrombosis
Interventions: DRUG: r-Hirudin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Positron Emission Mammography and Liquid Biopsy in Women With High-risk Breast Screenings
Status: RECRUITING
Conditions: Breast Cancer
Interventions: GENETIC: Liquid Biopsy|DEVICE: Positron Emission Mammography (PEM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia (CAP)
Status: COMPLETED
Conditions: Pneumonia
Interventions: DRUG: Cethromycin|DRUG: Clarithromycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A 12-weeks Study to Evaluate Sulforaphane in the Treatment of Depression
Status: UNKNOWN
Conditions: Depressive Disorder
Interventions: DRUG: sulforaphane|OTHER: placedo|DRUG: selective 5 - HT reuptake inhibitors (SSRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Avastin/Docetaxel/Carboplatin in Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Bevacizumab (Avastin)|DRUG: Carboplatin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Mechanism of POP Kidney Yin Deficiency Syndrome From the Interventional Effects of CLCF1
Status: UNKNOWN
Conditions: Postmenopausal Osteoporosis
Interventions: DRUG: Liuwei Dihuang Pills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Centella Asiatica on Xerotic Skin in Diabetes Mellitus Type 2
Status: UNKNOWN
Conditions: Xerosis Cutis|Diabetes Mellitus, Type 2
Interventions: DRUG: Centella Asiatica Extract|DRUG: Topical CA|DRUG: Petroleum jelly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of B-type Natriuretic Peptide (BNP) to Predict Closure of a Patent Ductus Arteriosus (PDA) in Premature Infants
Status: COMPLETED
Conditions: Indomethacin Therapy|Patent Ductus Arteriosus
Interventions: PROCEDURE: Withhold standard INDO dose if BNP < 100 pg/ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Two Titration Programs of Adding Insulin Detemir to OADs in Poorly Controlled Type 2 Diabetes
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: Active titration algorithm|BEHAVIORAL: Usual titration algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open, Non-comparative, Single-centre Post Marketing Clinical Followup (PMCF) Investigation to Evaluate Performance and Safety of the ALIAXIN Fillers Used as Intended
Status: RECRUITING
Conditions: Esthetics
Interventions: DEVICE: • ALIAXIN EV: Essential Volume • ALIAXIN FL: Lips • ALIAXIN SR: Shape & Restore • ALIAXIN GP: Global Performance • ALIAXIN LV: Lips Volume
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Evaluation of Low Phenylalanine Formulas
Status: ACTIVE_NOT_RECRUITING
Conditions: Phenylketonurias
Interventions: DIETARY_SUPPLEMENT: Glytactin|DIETARY_SUPPLEMENT: L-AA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence of TTYP01 Tablets in Healthy Adult Subjects
Status: COMPLETED
Conditions: Healthy Adult Subjects
Interventions: DRUG: TTYP01|DRUG: Radicava|DRUG: Radicava ORS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1/2 Trial of PTR-01 in Adult Patients With Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Status: COMPLETED
Conditions: Recessive Dystrophic Epidermolysis Bullosa
Interventions: DRUG: PTR-01|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin for Management of Hypervolemic Hyponatremia (AlbuCAT)
Status: UNKNOWN
Conditions: Hyponatremia With Excess Extracellular Fluid Volume|Cirrhosis, Liver
Interventions: DRUG: Albumin treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh
Status: RECRUITING
Conditions: Bone Loss, Alveolar
Interventions: PROCEDURE: zirconia barrier|PROCEDURE: titanium mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oocyte Cryopreservation by Slow Freezing and Vitrification
Status: TERMINATED
Conditions: Women Diagnosed With Cancer|Egg Donors|Single Women|Failed Sperm Procurement in IVF
Interventions: PROCEDURE: slow freeze|PROCEDURE: Vitrification
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison Between the Intubating Laryngeal Tube Suction and the Ambu AuraGain
Status: UNKNOWN
Conditions: Intubation; Difficult
Interventions: DEVICE: Intubating Laryngeal Tube Suction|DEVICE: Ambu AuraGain Laryngeal Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Abdominal Wall Transplant
Status: RECRUITING
Conditions: Transplant;Failure,Kidney|Transplant; Failure, Liver|Transplant; Failure, Bowel|Abdominal Wall Defect|Abdominal Wall Fistula|Abdominal Wall Hernia|Abdominal Wall Injury
Interventions: PROCEDURE: Abdominal Wall Transplant with another solid organ transplant|PROCEDURE: Abdominal Wall Transplant alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adipose Tissue & Uremia
Status: COMPLETED
Conditions: Chronic Kidney Disease - Stage V
Interventions: OTHER: Biopsy of abdominal subcutaneous white adipose tissue (2-3 g)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Antimicrobial Photodynamic Therapy as an Adjunct for Management of Deep Caries Lesions
Status: UNKNOWN
Conditions: Caries
Interventions: PROCEDURE: Caries removal with a lowspeed drill|PROCEDURE: Partial removal of carious tissue with the administration of Papacarie™|PROCEDURE: Partial removal of carious tissue with the administration of Papacarie™ and application of Bixa Orellana extract (20%)|PROCEDURE: Partial removal of carious tissue with the administration of Papacarie™, application of Bixa Orellana extract (20%) and LED (aPDT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin for the Treatment of Children and Adolescents With Autism Spectrum Disorders (ASD)
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: DRUG: Intranasal Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy and Safety of EGFR-TKI Combined With Nimotuzumab in the Treatment of Leptomeningeal Metastases From Lung Cancer
Status: UNKNOWN
Conditions: Leptomeningeal Metastasis|Lung Cancer
Interventions: DRUG: Nimotuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell Disease
Status: NOT_YET_RECRUITING
Conditions: Sickle Cell Disease
Interventions: PROCEDURE: Allogeneic matched related haematopoietic stem cell transplantation|OTHER: Standard arm
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase Ia Clinical Study of QLF31907 Injection in Patients With Advanced Malignant Tumors
Status: RECRUITING
Conditions: Solid Tumor|Lymphoma, Non-Hodgkin
Interventions: DRUG: QLF31907
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The TLC2 (Teaching Healthy Lifestyles to Caregivers 2)/CALM (Counseling Advice for Lifestyle Management) Study
Status: COMPLETED
Conditions: Health Behavior|Psychological Stress|Healthy
Interventions: BEHAVIORAL: The Stanford Active Choices program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pharmacokinetics, Safety, and Tolerability of IM Letrozole LEBE in Healthy Post-menopausal Women
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Letrozole LEBE 75 mg|DRUG: Letrozole LEBE 150 mg|DRUG: Letrozole LEBE 225 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Mifepristone for Fibroids
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Mifepristone|DRUG: Inert Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability and Efficacy of FOLFOX + CT-011 Versus FOLFOX Alone
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: CT-011|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial to Evaluate Reduction in Inflammation in Patients With Advanced Chronic Renal Disease Utilizing Antibody Mediated IL-6 Inhibition in Japan.
Status: COMPLETED
Conditions: Chronic Kidney Disease|Inflammation|Cardiovascular Risk
Interventions: DRUG: Ziltivekimab|DRUG: Placebo (ziltivekimab)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Efficacy of Switching From Talipexole to Pramipexole in Patients With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: BI-Sifrol®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comperative Trial Between an Accommodative Iol and Monofocal Iol
Status: WITHDRAWN
Conditions: CATARACT SURGERY
Interventions: DEVICE: Acrysof|DEVICE: Acuity's AIOL
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Miltefosine or Thermotherapy for Cutaneous Leishmaniasis in Colombia.
Status: COMPLETED
Conditions: Cutaneous Leishmaniasis
Interventions: DRUG: Miltefosine|DEVICE: Thermotherapy|DRUG: Glucantime®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Clofarabine in Combination With Etoposide and Cyclophosphamide in Children With Acute Leukemias.
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myelogenous Leukemia|Relapsed Leukemia
Interventions: DRUG: clofarabine|DRUG: Etoposide|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: KoMAC Videolaryngoscope for Double-lumen Intubation
Status: COMPLETED
Conditions: Intubation
Interventions: DEVICE: KoMAC videolaryngoscope|DEVICE: Macintosh Laryngoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 2 Study of OTL38 for Intra-operative Imaging of Folate Receptor-alpha Positive Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: OTL38|DEVICE: Near infrared camera imaging system|PROCEDURE: Laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pentosan Polysulfate Sodium and Meclofenamic Acid as Treatments in Patients With Psychotic Disorders
Status: COMPLETED
Conditions: Psychotic Disorders|Schizophrenia|Schizoaffective Disorder|Bipolar Disorder
Interventions: DRUG: Meclofenamic acid|DRUG: Pentosan polysulfate sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Antibiotic Prophylaxis Associated With Dental Implant Surgery
Status: COMPLETED
Conditions: Infection Control|Antibiotic Prophylaxis
Interventions: DRUG: Amoxicillin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment
Status: COMPLETED
Conditions: Desmoid Tumors
Interventions: DEVICE: "cryoprobes"
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized, Placebo-controlled, 2 Period, Single-blind, Sequential, Multiple Ascending Dose Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: DS-7309|DRUG: placebo|DRUG: Metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Dynamic Taping on Landing Kinematics and Kinetics in Volleyball Players With Symptoms of Patellar Tendinopathy
Status: COMPLETED
Conditions: Biomechanical Phenomena
Interventions: DEVICE: Dynamic tape|DEVICE: Sham tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Hyperoxygenated Fatty Acids in a Surgical Wound After Laparoscopic Cholecystectomy.
Status: COMPLETED
Conditions: Surgical Site Infection
Interventions: PROCEDURE: PrevOmega|PROCEDURE: Physiological saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Alcohol Dependency Study: Combining Medication Treatment for Alcoholism
Status: UNKNOWN
Conditions: Alcoholism
Interventions: DRUG: ondansetron + cognitive behavioral therapy|DRUG: topiramate + cognitive behavioral therapy|DRUG: Placebo + cognitive behavioral therapy|DRUG: ondansetron + topiramate + cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of GSK1605786 for Treatment of Patients With Active Ulcerative Colitis
Status: WITHDRAWN
Conditions: Colitis, Ulcerative
Interventions: DRUG: GSK1605786|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Immune Response to LC002, an Experimental Therapeutic Vaccine, in Adults Receiving HAART
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: LC002 standard vaccination|BIOLOGICAL: LC002 high-dose vaccination|BIOLOGICAL: LC002 placebo vaccination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pre-op Paravertebral Blocks to Decrease Post-op Pain Following Mastectomy With Immediate Tissue Expander (TE) Reconstruction
Status: TERMINATED
Conditions: Postoperative Pain|Postoperative Nausea and Vomiting|Quality of Life
Interventions: DRUG: Ropivacaine|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of ALKS 5461 in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: ALKS 5461|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Dyadic Parent-child Self-compassion Program on Children' Psychological Well-being: A Pilot Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Psychological Well-Being
Interventions: BEHAVIORAL: Self-compassion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer
Status: RECRUITING
Conditions: Carcinoma Breast|Triple-negative Breast Cancer|Invasive Ductal Carcinoma, Breast
Interventions: DRUG: Huaier Granule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ocrelizumab or Alemtuzumab Compared With Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis - a Phase-2 Randomised Controlled Trial
Status: TERMINATED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Ocrelizumab|DRUG: Alemtuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dasatinib in Treating Patients With Stage III Melanoma That Cannot Be Removed By Surgery or Stage IV Melanoma
Status: COMPLETED
Conditions: Recurrent Melanoma|Stage IIIA Melanoma|Stage IIIB Melanoma|Stage IIIC Melanoma|Stage IV Melanoma
Interventions: DRUG: dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural Counseling
Status: COMPLETED
Conditions: Smoking Cessation|Psychiatric Illness
Interventions: DRUG: Champix|DRUG: Transdermal Nicoderm patch combined with gum or inhaler|DRUG: Transdermal Nicoderm patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Flortaucipir F18|PROCEDURE: Brain PET Scan|PROCEDURE: Whole body PET scan|DRUG: Florbetapir F 18|PROCEDURE: Brain MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug-Drug Interaction Study to Evaluate the Effect of Inhibition of UGTs on the PK of Ecopipam and Its Active Metabolite
Status: COMPLETED
Conditions: Drug Interaction
Interventions: DRUG: ecopipam HCL|DRUG: Mefenamic acid|DRUG: Divalproex Sodium ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mindfulness-Based Pain Management (MBPM) for Patients With Chronic Musculoskeletal Pain
Status: COMPLETED
Conditions: Chronic Pain
Interventions: BEHAVIORAL: Mindfulness-based pain management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial of Cadonilimab Plus Regorafenib in Patients With Hepatocellular Carcinoma Who Failed Camrelizumab Combined With Apatinib
Status: NOT_YET_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cadonilimab+regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: aiTBS for Relieving NSSI in Depressive Patients
Status: RECRUITING
Conditions: Major Depressive Disorder|Bipolar Depression
Interventions: DEVICE: Active iTBS|DEVICE: Sham iTBS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer
Status: RECRUITING
Conditions: Breast Cancer|Fatigue
Interventions: DIETARY_SUPPLEMENT: QISENG|DIETARY_SUPPLEMENT: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Yoga Therapy in Treating Patients With Malignant Brain Tumors
Status: TERMINATED
Conditions: Adult Anaplastic Astrocytoma|Adult Anaplastic Ependymoma|Adult Anaplastic Meningioma|Adult Anaplastic Oligodendroglioma|Adult Brain Stem Glioma|Adult Choroid Plexus Tumor|Adult Diffuse Astrocytoma|Adult Ependymoblastoma|Adult Ependymoma|Adult Giant Cell Glioblastoma|Adult Glioblastoma|Adult Gliosarcoma|Adult Grade II Meningioma|Adult Medulloblastoma|Adult Meningeal Hemangiopericytoma|Adult Mixed Glioma|Adult Oligodendroglioma|Adult Papillary Meningioma|Adult Pineal Gland Astrocytoma|Adult Pineoblastoma|Adult Pineocytoma|Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)|Recurrent Adult Brain Tumor
Interventions: PROCEDURE: yoga therapy|OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intracorporeal Anastomosis Accelerates Bowel Function in Comparison to Extracorporeal Anastomosis in Laparoscopic Right Hemicolectomy - a Randomized Control Trial.
Status: COMPLETED
Conditions: Right Hemicolectomy
Interventions: PROCEDURE: Intracorporeal anastomosis|PROCEDURE: Extracorporeal anastomosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Integrated Traditional Chinese and Clinical Medicine for Chronic Hepatitis B and Its Complication
Status: UNKNOWN
Conditions: Hepatic Encephalopathy|Cirrhosis, Liver|Portosystemic Shunt
Interventions: DRUG: traditional Chinese medicine1 and traditional Chinese medicine 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collaborating to Implement Cross-System Interventions in Child Welfare and Substance Use
Status: COMPLETED
Conditions: Substance Use|Implementation|Child Maltreatment|System Fragmentation
Interventions: OTHER: Collaboration Decision Support Guide|OTHER: General Collaboration Support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Dose-Finding Study of E7389 in Combination With Carboplatin in Patients With Solid Tumors
Status: COMPLETED
Conditions: Cancer
Interventions: DRUG: E7389 + carboplatin AUC 5|DRUG: E7389 + carboplatin AUC 6|DRUG: E7389+carboplatin AUC 6
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relative Bioavailability of Two Different Milk Thistle Formulations
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Product B® IsaGenesis®|DIETARY_SUPPLEMENT: IsaGenesis®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Feasibility Study of the Hemolung Respiratory Assist System (Germany)
Status: COMPLETED
Conditions: Hypercapnic Respiratory Failure, COPD, ARDS
Interventions: DEVICE: Hemolung Respiratory Assist System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Method of Anaesthesia on the Safety and Effectiveness of Radical Retropubic Prostatectomy
Status: COMPLETED
Conditions: Prostatic Neoplasm
Interventions: PROCEDURE: General Anaesthesia|PROCEDURE: Combined (Epidural and Spinal) Anaesthesia|PROCEDURE: Open Retropubic Radical Prostatectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicentre Interventional Pilot Study on the Evaluation of the Functionality, Safety and Reliability of a New Robotic Prosthesis for the Lower Limb at the Transfemoral Level
Status: COMPLETED
Conditions: Amputation|Amputation; Traumatic, Leg, Lower
Interventions: DEVICE: WRL ATP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Study to Evaluate the Safety of Pembrolizumab in Participants With Unresectable or Metastatic Melanoma or Non-small Cell Lung Cancer in India (MK-3475-593/KEYNOTE-593)
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung|Melanoma
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DRUG: Atorvastatin 10 mg|DRUG: Ezetimibe 10 mg/simvastatin 20 mg|DRUG: Atorvastatin 20 mg|DRUG: Ezetimibe 10 mg/simvastatin 40 mg|DRUG: Atorvastatin 40 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Home-based Transcranial Direct Current Stimulation in Postpartum Depression: the Feasibility Study and Pilot Study
Status: NOT_YET_RECRUITING
Conditions: Postnatal Depression
Interventions: DEVICE: Transcranial Direct Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Shock Wave Therapy Plus Exercise in GTPS
Status: ACTIVE_NOT_RECRUITING
Conditions: Greater Trochanteric Pain Syndrome of Both Lower Limbs
Interventions: OTHER: Rehabilitation program based on the strengthening of gluteal muscles|OTHER: Extracorporeal shock wave therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Multiple Doses of PRS-060 Administered by Oral Inhalation in Subjects With Mild Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: PRS-060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Androgenetic Alopecia in Males
Status: COMPLETED
Conditions: Androgenetic Alopecia|Hair Loss|Male Pattern Baldness
Interventions: DEVICE: HairMax LaserComb 2009, 7 Beam|DEVICE: HairMax LaserComb
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anti-Mullerian Hormone (AMH) is a Marker for Ovarian Reserve. There Are Many Studies About AMH Changes in Ovarian Surgery, But Little is Known for Other Surgeries. We Seek to Investigate the Hormone Variations Before and After Uterine Artey Ligation for Postpartum Hemorrage (PPH)
Status: COMPLETED
Conditions: Anti-Mullerian Hormone Deficiency|Post Partum Hemorrhage
Interventions: OTHER: anti- mullerian hormone
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Heat Therapy for Peripheral Arterial Disease (HEATPAD)
Status: NOT_YET_RECRUITING
Conditions: Peripheral Arterial Disease|Intermittent Claudication|Critical Limb Ischemia
Interventions: DEVICE: AirGlove
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Caprini Score in Venous Surgery: a Prospective Cohort Study
Status: RECRUITING
Conditions: Venous Thromboembolism|Varicose Veins
Interventions: PROCEDURE: EVLT|PROCEDURE: RFA|PROCEDURE: USFS|PROCEDURE: HL/stripping|PROCEDURE: Miniphlebectomy|PROCEDURE: Sclerotherapy|DEVICE: GCS|DRUG: LMWH
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Cancer Stage IV|Mismatch Repair-deficient (dMMR)|Microsatellite Instability-high (MSI-H)
Interventions: DRUG: Cadonilimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Methotrexate in Induction and Maintenance of Steroid Free Remission in Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of STG320 Sublingual Tablets of HDM Allergen Extracts in Adults and Adolescents With HDM-associated AR
Status: COMPLETED
Conditions: Rhinitis, Allergic, Perennial|House Dust Mite Allergy
Interventions: BIOLOGICAL: 300 IR|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does "Kinesio-taping" Affect Balance in Healthy Individuals?
Status: COMPLETED
Conditions: Balance
Interventions: DEVICE: Therapeutic Kinesio-taping|DEVICE: Sham Kinesio-taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days
Status: COMPLETED
Conditions: Secondary Hyperoxaluria|Nephrolithiasis|Hyperoxaluria|Kidney Stones|Dietary Hyperoxaluria
Interventions: DRUG: ALLN-177|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tocilizumab in Participants With Active Rheumatoid Arthritis (RA) and an Inadequate Response to Non-Biological Disease-modifying Anti-rheumatic Drugs (DMARDs)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Embryo Transfer in Egg Donation Recipients With Transvaginal and Transabdominal Ultrasound
Status: TERMINATED
Conditions: Infertility
Interventions: PROCEDURE: Transvaginal ultrasound-guided embryo transfer|PROCEDURE: Transabdominal ultrasound-guided embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Negative Pressure Wound Therapy for Soft Tissue Injuries of Foot and Ankle in Patients at a Tertiary Care Hospital
Status: COMPLETED
Conditions: Soft Tissue Injuries
Interventions: PROCEDURE: Negative Pressure Wound Therapy|PROCEDURE: Conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trial Of Neurostimulation Treatment and Investigation for Causes of Functional Motor Symptoms: a Pilot Study
Status: RECRUITING
Conditions: Functional Neurological Symptom Disorder
Interventions: DEVICE: Transcranial magnetic stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Fallopian Tube Catheterization During Hysterosalpingo-foam Sonography (HyFoSy)
Status: UNKNOWN
Conditions: Fallopian Obstruction Tube
Interventions: PROCEDURE: Ultrasound guided transcervical fallopian tube catheterization during hysterosalpingo-foam sonography in the treatment of proximal tubal obstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Pain Disability With the Use of Oral Cannabinoids
Status: RECRUITING
Conditions: Chronic Pain|Opioid Use|Cannabis
Interventions: DRUG: CBD oil ( MPL-001)|DRUG: CDB+THC oil (MPL-005)|DRUG: Placebo oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of CPAP on Myocardial Dysfunction in Type 2 Diabetes Mellitus and Obstructive Sleep Apnea Patients
Status: COMPLETED
Conditions: Sleep Apnea, Obstructive|Diabetes Mellitus, Type 2|Continuous Positive Airway Pressure|Myocardial Dysfunction|Echocardiography|Obesity
Interventions: DEVICE: Sham CPAP|DEVICE: Therapeutic CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT