pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Efficacy of Bifidus DR10 and Oligo Saccharides / Micronutrient Fortification of Milk
Status: COMPLETED
Conditions: Diarrhea|Pneumonia|Febrile Illness|Growth|Child Development
Interventions: DRUG: Micronutrient (Zinc and Iron) fortification|DRUG: Pre and Probiotic fortification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: Effect of a Fermented Milk Product With Probiotics Alone or in Combination With Fibers on Constipation Symptoms
Status: COMPLETED
Conditions: Healthy|Constipation
Interventions: OTHER: Fermented milk product containing Probiotics|OTHER: Fermented Milk Product containing Probiotics + Fibers C|OTHER: Fermented Milk Product containing Probiotics + Fibers W|OTHER: Non fermented Milk Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract
Status: COMPLETED
Conditions: HIV/AIDS|Menopause|Inflammation Vagina
Interventions: DRUG: Tenofovir|DRUG: Emtricitabine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: CAPO: Continuous Glucose Monitoring in A2 Gestational Diabetes and Pregnancy Outcomes
Status: RECRUITING
Conditions: Gestational Diabetes|Maternal Complication of Pregnancy
Interventions: DEVICE: Continuous Glucose Monitor|OTHER: Routine Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Stem Cell Transplantation in Patients With Primary Biliary Cirrhosis
Status: WITHDRAWN
Conditions: Primary Biliary Cirrhosis
Interventions: BIOLOGICAL: Non-myeloablative Hematopoietic Stem Cell Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Assessing the Effects of Acupuncture in Parkinson's Disease Patients With Chronic Appendicitis
Status: RECRUITING
Conditions: Parkinson's Disease|Chronic Appendicitis|Acupuncture
Interventions: OTHER: Acupuncture treatment|OTHER: Sham acupuncture treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of Bowel Preparation Before Colonoscopy
Status: COMPLETED
Conditions: Bowel Cleansing Prior to Colonoscopy
Interventions: DRUG: FM-602|DRUG: Marketed Bowel Cleanser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Vitamin D for Schizophrenia
Status: COMPLETED
Conditions: Clozapine Resistant Schizophrenia
Interventions: DRUG: Vitamin D3|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness
Status: RECRUITING
Conditions: Schizophrenia|Bipolar Disorder|Major Depressive Disorder|Schizo Affective Disorder
Interventions: BEHAVIORAL: FOCUS participants
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Anemia
Interventions: DRUG: cyclosporine|DRUG: fludarabine|DRUG: mycophenolate mofetil|PROCEDURE: Bone Marrow Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Compare FOFLOX4 in Preoperative and Postoperative and Postoperative in Resectable Liver Metastasis Colorectal Cancer (MCC)
Status: UNKNOWN
Conditions: Colorectal Cancer|Liver Metastasis
Interventions: DRUG: FOFLOX4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Dysbiosis and Immune Response in Bronchiolitis in Under 12 Months -Old Infants
Status: NOT_YET_RECRUITING
Conditions: Bronchiolitis
Interventions: OTHER: Sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of ACAF and ACCF in the Treatment of Cervical OPLL
Status: UNKNOWN
Conditions: Ossification of Posterior Longitudinal Ligament
Interventions: PROCEDURE: ACAF surgery|PROCEDURE: ACCF surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial
Status: COMPLETED
Conditions: Appendicitis
Interventions: DRUG: Cefoxitin, Ertapenem, Moxifloxacin, Tigecycline, Ticarcillin-Clavulanic Acid; Metronidazole plus Cefazolin, Cefuroxime, Ceftriaxone, Cefotaxime, Ciprofloxacin, or Levofloxacin|PROCEDURE: Appendectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Device Mixing in Asthma, a General Practice Research Database Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Initiation of beclometasone via the Easibreathe device plus salbutamol via the Easibreathe device|DRUG: Initiation of beclometasone via the Easibreathe device plus salbutamol via and MDI device|DRUG: Increase of beclometasone via the Easibreathe device plus salbutamol via the Easibreathe device|DRUG: Increase of beclometasone via the Easibreathe device plus salbutamol via an MDI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Photodynamic Therapy in Treatment of Verrucae
Status: UNKNOWN
Conditions: Verruca Vulgaris
Interventions: OTHER: methylene blue / IPL|OTHER: IPL|OTHER: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Eletriptan for the Treatment of Migraine in Patients Not Satisfied With Rizatriptan Therapy
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Eletriptan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Dual Task Exercise on Cognitive and Physical Function in the Elderly With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Dysfunction|Mild Cognitive Impairment
Interventions: BEHAVIORAL: dual task exercise|BEHAVIORAL: home exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of an Edible Colonoscopy Preparation
Status: COMPLETED
Conditions: Colon Prep for Colonoscopy
Interventions: DRUG: ECP Colon Prep Kit|DRUG: MoviPrep®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 2 Study of CDX-0159 in Patients With Chronic Spontaneous Urticaria
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Spontaneous Urticaria
Interventions: BIOLOGICAL: barzolvolimab|DRUG: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nitric Oxide During Bypass for Arterial Switch Operation
Status: COMPLETED
Conditions: Low Cardiac Output Syndrome|Transposition of Great Vessels
Interventions: DRUG: Nitric Oxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Psychological Interventions to Prevent Late Effects in Breast Cancer
Status: COMPLETED
Conditions: Pain, Postoperative|Fatigue|Breast Cancer
Interventions: BEHAVIORAL: Medical hypnosis|BEHAVIORAL: Internet-based Acceptance and Commitment Therapy (iACT)|BEHAVIORAL: Mindfulness session|BEHAVIORAL: Treatment as Usual (TAU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Estimate Effect of 4 Different Doses of AZD3355 on Reflux Episodes, Which Patients With Gastroesophageal Reflux Disease (GERD) May Experience
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease
Interventions: DRUG: AZD3355|DRUG: AZD3355|DRUG: AZD3355|DRUG: AZD3355|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benefit and Tolerability of IQP-AS-105 in Reducing Susceptibility to Upper Respiratory Tract Infections
Status: TERMINATED
Conditions: Common Cold|Upper Respiratory Tract Infections
Interventions: DIETARY_SUPPLEMENT: IQP-AS-105|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Neoadjuvant Icotinib With Chemotherapy for Epidermal Growth Factor Receptor(EGFR)-Mutated Resectable Lung Adenocarcinoma
Status: NOT_YET_RECRUITING
Conditions: NSCLC|EGF-R Positive Non-Small Cell Lung Cancer
Interventions: DRUG: Icotinib|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Pemetrexed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Urothelial Carcinoma
Interventions: BIOLOGICAL: INO-5401|BIOLOGICAL: INO-9012|DRUG: Atezolizumab|DEVICE: CELLECTRA™ 2000
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Performance of the Mainz Biomed Colorectal Cancer Screening Test for Colorectal Cancer and Advanced Adenoma
Status: NOT_YET_RECRUITING
Conditions: Colorectal Cancer|Colorectal Neoplasms|Colorectal Polyp|Colorectal Adenoma
Interventions: DEVICE: Mainz Biomed Colorectal Cancer Screening Test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Indomethacin Capsules to Treat Pain Following Bunionectomy
Status: COMPLETED
Conditions: Other Acute Postoperative Pain
Interventions: DRUG: Indomethacin|DRUG: Indomethacin|DRUG: Indomethacin|DRUG: Celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Evaluation of Internet-based Carbohydrate Counting Education for Adolescents With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: BEHAVIORAL: In-person Carbohydrate Counting Class|BEHAVIORAL: Online Carbohydrate Counting Tutorial
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Curcumin in Cutaneous T-cell Lymphoma Patients
Status: WITHDRAWN
Conditions: Cutaneous T-cell Lymphoma
Interventions: DRUG: Curcumin (Turmeric)|BEHAVIORAL: Questionnaires|OTHER: Photos
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dietetic Intervention With Soluble Fiber in Type 2 Diabetes Mellitus (DM) Patients With Metabolic Syndrome (MS)
Status: COMPLETED
Conditions: Metabolic Syndrome|Albuminuria
Interventions: DIETARY_SUPPLEMENT: guar gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repurposing 5-Azacytidine for the Treatment of Muscle Contractures in Children With Cerebral Palsy
Status: NOT_YET_RECRUITING
Conditions: Cerebral Palsy|Contracture
Interventions: DRUG: Placebo for the AZA 10mg/m^2|DRUG: Placebo for the AZA 20mg/m^2|DRUG: Placebo for the AZA 35mg/m^2|DRUG: Placebo for the AZA 75mg/m^2|DRUG: 5-Azacytidine 10mg/m^2|DRUG: 5-Azacytidine 20mg/m^2|DRUG: 5-Azacytidine 35mg/m^2|DRUG: 5-Azacytidine 75mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial With Dronedarone to Prevent Hospitalization or Death in Patients With Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation|Atrial Flutter
Interventions: DRUG: dronedarone (SR33589)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Staphylococcus Aureus Colonization in Hand Eczema
Status: COMPLETED
Conditions: Hand Eczema|Foot Eczema
Interventions: DRUG: Retapamulin 1% ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Green Tea Extract in Treating Patients With Low-Risk Prostate Cancer
Status: TERMINATED
Conditions: Stage I Prostate Cancer|Stage IIA Prostate Cancer|Stage IIB Prostate Cancer
Interventions: OTHER: active surveillance|DRUG: Sunphenon|OTHER: laboratory biomarker analysis|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Empagliflozin in Heart Failure Patients With Reduced Ejection Fraction
Status: COMPLETED
Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: DRUG: Empagliflozin 10 MG|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Systemic Exposure Study of BL-7010 in Well-Controlled Celiac Patients.
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: BL-7010|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Trial Comparing Laparoscopic Nissen Against Anterior Partial Fundoplication in Treating Gastroesophageal Reflux Disease Among Chinese Patients
Status: UNKNOWN
Conditions: Gastroesophageal Reflux Disease
Interventions: PROCEDURE: Laparoscopic Nissen Fundoplication|PROCEDURE: Laparoscopic anterior partial fundoplication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study
Status: RECRUITING
Conditions: Cancer
Interventions: DRUG: Ipatasertib|DRUG: Tiragolumab|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postprandial Metabolic and Appetite Responses to Different Food Intake Sequences in Athletes
Status: RECRUITING
Conditions: Healthy|Nutrition, Healthy|Postprandial Hyperglycemia|Hunger|Craving
Interventions: OTHER: Carbohydrate-last meal pattern|OTHER: Carbohydrate-first meal pattern
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Classifying for HER2 Dependence to De-Escalate Neoadjuvant Chemotherapy in Patients With HER2+ Early Breast Cancer Undergoing HER2 Double-Blockade
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: PHESGO
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of 0.1% Olopatadine Hydrochloride Ophthalmic Solution in Pediatric Patients
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Olopatadine hydrochloride ophthalmic solution 0.1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
Status: COMPLETED
Conditions: Scar Prevention
Interventions: DRUG: EXC 001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Status: RECRUITING
Conditions: Cholecystitis, Acute|Cholelithiasis|Nausea, Postoperative|Vomiting, Postoperative|Pain, Postoperative
Interventions: DEVICE: Acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimization Dose Study on Pharmacokinetics and Pharmacodynamics of Colistin in Critically Ill Patients
Status: COMPLETED
Conditions: Critical Illness
Interventions: DRUG: Colistin 6 million units + 240mg/8h|DRUG: Colistin 6 million units + 360mg/12h
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress
Status: COMPLETED
Conditions: Ischemic Stress|Transient Non-Lethal Ischemia
Interventions: DRUG: Sodium Nitrate|DRUG: Acetylcholine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Partial Neuromuscular Blockade in Acute Respiratory Distress Syndrome
Status: TERMINATED
Conditions: Respiratory Insufficiency|Extracorporeal Membrane Oxygenation Complication|Neuromuscular Blockade
Interventions: DRUG: Neuromuscular blockade
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Observational Study to Evaluate the Simplified-STroke REhabilitation Assessment of Movement (S-STREAM) Scale in Subjects Who Have Experienced a Nonhemorrhagic Ischemic Stroke
Status: COMPLETED
Conditions: Nonhemorrhagic Ischemic Stroke|Motor Function
Interventions: OTHER: Observational study
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: BIOLOGICAL: CH505M5 N197D mRNA-gp160|BIOLOGICAL: CH505 TF mRNA-gp160
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transsternal Versus Transcervical Thymectomy
Status: COMPLETED
Conditions: Myasthenia Gravis, Thymectomy
Interventions: PROCEDURE: Transcervical Thymectomy|PROCEDURE: Transsternal Thymectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimizing Exposure Therapy With Mental Rehearsal
Status: COMPLETED
Conditions: Anxiety Disorders|Arachnophobia
Interventions: BEHAVIORAL: Mental Rehearsal|BEHAVIORAL: Exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of MCV4 in Volunteers Aged 6 Months-5 Years
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Population
Interventions: BIOLOGICAL: Group ACYW135 Meningococcal Polysaccharide Conjugate Vaccine|BIOLOGICAL: Group A and C Meningococcal Polysaccharide Vaccine|BIOLOGICAL: Group ACYW135 Meningococcal Polysaccharide Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Exploratory Study of Efficacy and Safety of Iruplinalkib Tablets in Patients With ROS1 Positive Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: Iruplinalkib tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare FCD105 Foam to Minocycline 3% Foam, Adapalene 0.3% Foam and Vehicle Foam.
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: COMBINATION_PRODUCT: FCD105|DRUG: 3% Minocycline Foam|DRUG: 0.3% Adapalene Foam|OTHER: Vehicle Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy in Treating Patients With Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: autologous tumor cell vaccine|BIOLOGICAL: sargramostim|BIOLOGICAL: tumor-draining lymph node lymphocyte therapy|DRUG: cyclophosphamide|PROCEDURE: conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions
Status: COMPLETED
Conditions: Emergency Contraception
Interventions: DRUG: Use Phase (Ulipristal Acetate, 30 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up
Status: TERMINATED
Conditions: Prostatic Hyperplasia|Urinary Retention
Interventions: DRUG: Doxazosin GITS (Cardura XL)|DRUG: Terazosin (Hytrin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Bioequivalence of R406 in Healthy Volunteers When Given 100mg and 150 mg of Fostamatinib
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: MCC-based 13% drug loaded tablets|DRUG: Mannitol-based 38% drug-loaded tablet|DRUG: MCC-based 13% drug loaded tablets|DRUG: Mannitol-based 38% drug-loaded tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: An Extension Study of JR-171-101 Study in Patients With MPS I
Status: ACTIVE_NOT_RECRUITING
Conditions: Mucopolysaccharidosis I
Interventions: DRUG: JR-171 (lepunafusp alfa)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Multi-endodiathermy Retinectomy Versus Relaxing Retinectomy for Retinal Re-detachment
Status: UNKNOWN
Conditions: Retinal Redetachment in Silicone Oil-filled Eyes
Interventions: PROCEDURE: multi-endodiathermy retinectomy|PROCEDURE: relaxing retinectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety & Efficacy of Topical ATx201 OINTMENT in Adolescents and Adults With Mild to Moderate AD
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: ATx201|DRUG: ATx201 OINTMENT vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scanning the Meiotic Spindle in Assisted Reproductive Techniques to Assess Oocyte Quality
Status: ACTIVE_NOT_RECRUITING
Conditions: Infertility|Infertility, Male|Infertility, Female
Interventions: PROCEDURE: Meiotic spindle status observation in polarized light|PROCEDURE: ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: The Impact of Cognitive Behavioral Therapy for Insomnia (CBT-I) on Glycemic Control in Older Type 2 Diabetes (T2D) Comorbid With Insomnia
Status: NOT_YET_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Insomnia
Interventions: BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
Status: RECRUITING
Conditions: Urethral Stricture, Male
Interventions: DRUG: Standard Buccal Harvest|DRUG: Basic buccal procedure + Long acting local|DRUG: Basic buccal procedure + Buccal block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Untreated Ovarian, Peritoneal, or Fallopian Tube Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel|DRUG: pegylated liposomal doxorubicin hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prognostic Utility of the Imaging and Biological Signatures in Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: DEVICE: 18F-FDG PET/CT, MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Demonstrate Bioequivalence Between a 12-mg Dose of an Oral Suspension Formulation of Perampanel and a 12-mg Tablet Formulation of Perampanel Under Fasted and Fed Conditions in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prism Adaptation Therapy (PAT) for Right Brain Stroke Rehabilitation
Status: RECRUITING
Conditions: Spatial Neglect After Right Brain Stroke
Interventions: BEHAVIORAL: Prism adaptation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Metanephrines in Obstructive Sleep Apnoea
Status: COMPLETED
Conditions: Pheochromocytoma|Obstructive Sleep Apnea|Catecholamine; Secretion
Interventions: DIAGNOSTIC_TEST: Measurement of Urine and plasma metanephrines
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRI-Guided Radiation Therapy in Treating Patients Who Have Undergone Surgery to Remove the Prostate
Status: COMPLETED
Conditions: Prostate Cancer|Adenocarcinoma of the Prostate|Stage I Prostate Cancer|Stage II Prostate Cancer|Stage III Prostate Cancer
Interventions: PROCEDURE: radiation therapy treatment planning/simulation|PROCEDURE: intensity-modulated radiation therapy|PROCEDURE: image-guided radiation therapy|PROCEDURE: magnetic resonance imaging|PROCEDURE: computed tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study of BIIB074 and an Oral Contraceptive Regimen
Status: COMPLETED
Conditions: Drug Interactions
Interventions: DRUG: BIIB074|DRUG: OC (ethinyl estradiol and levonorgestrel)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-stroke Pain taVNS
Status: RECRUITING
Conditions: Stroke|Pain
Interventions: DEVICE: Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)|DEVICE: Sham Auricular Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of CVX-096 (PF-04856883) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883|BIOLOGICAL: PF-04856883
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Abiliti™ Treatment in Obese Subjects
Status: UNKNOWN
Conditions: Obesity|Morbid Obesity
Interventions: DEVICE: abiliti system implant|DEVICE: Laparoscopic adjustable gastric band (Allergan Lap Band)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: gonadotrophin releasing hormone|DRUG: cyproterone acetate|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effect of Left Posterior Pericardiotomy for the Prevention of POAF
Status: RECRUITING
Conditions: Coronary Artery Disease|Atrial Fibrillation New Onset|Pericardial Effusion
Interventions: PROCEDURE: left posterior pericardiostomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment Study Comparing Aripiprazole Once Monthly With Standard of Care Medication in Outpatients With Schizophrenia
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: Aripiprazole Once-Monthly|DRUG: Oral Antipsychotic (i.e. aripiprazole, risperidone, lurasidone, quetiapine, olanzapine, ziprasidone, etc)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Neuromuscular Electrical Stimulation to Increase Spontaneous Physical Activity in Obesity Patient
Status: COMPLETED
Conditions: Obesity|Number of Steps Per Day < 7000
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial of Home Telemonitoring for Elderly People
Status: UNKNOWN
Conditions: Diabetes Mellitus|Chronic Heart Failure|Chronic Obstructive Pulmonary Disease
Interventions: DEVICE: Wireless monitors for disease specific clinical parameters.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Juniperus Oxycedrus and Cupressus Arizonica Allergen Extracts Standardisation.
Status: UNKNOWN
Conditions: Allergy Pollen|Allergic Reaction|Allergic Skin Reaction
Interventions: OTHER: Allergenic extract
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: RYGB and the Gastric Adipose Axis
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: human ghrelin|OTHER: very low calorie diet|PROCEDURE: Hyperinsulinemic/Euglycemic Clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Genetic Newborn Screening for Cystinosis and Spinal Muscular Atrophy
Status: COMPLETED
Conditions: Cystinosis|Cystinosis, Nephropathic|Spinal Muscular Atrophy
Interventions: DIAGNOSTIC_TEST: molecular-based screening
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pre-pectoral Breast Reconstruction PART 1
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DEVICE: DTI with Acellular Dermal Matrix (CELLIS® Breast)|DEVICE: DTI with Titanium Coated Polypropylene Mesh (TiLOOOP® Bra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Mini Gastric Bypass and Roux-en-Y Gastric Bypass
Status: ACTIVE_NOT_RECRUITING
Conditions: Morbid Obesity
Interventions: PROCEDURE: Roux-en-y gastric bypass|PROCEDURE: Single anastomosis gastric bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Glycaemic Index Variation on Blood Glucose and Mood in Healthy Participants Across the Day
Status: COMPLETED
Conditions: Mood|Diet Modification|Glucose, Low Blood|Glucose, High Blood
Interventions: DIETARY_SUPPLEMENT: Low Glycaemic Diet|DIETARY_SUPPLEMENT: High Glycaemic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY3015014 in Healthy Participants With High Cholesterol
Status: COMPLETED
Conditions: Healthy Volunteers|Hypercholesterolemia
Interventions: DRUG: LY3015014|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
Status: WITHDRAWN
Conditions: Caries,Dental|Apical Periodontitis
Interventions: DRUG: Kovanaze Nasal Spray|DRUG: Articaine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: Valemetostat tosylate|DRUG: T-DXd|DRUG: Dato-DXd
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Safety, Tolerability and Pharmacokinetics of Single Oral JTT-251 Doses in Healthy and Type 2 Diabetic Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus
Interventions: DRUG: JTT-251 or Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2
Status: COMPLETED
Conditions: Leukemia|Lymphoma
Interventions: DRUG: Rasburicase|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Viusal Outcomes After Implantation of the POD 26% FineVision Toric (PhysIOL) and POD 26% Toric (PhysIOL)
Status: WITHDRAWN
Conditions: Cataract
Interventions: DEVICE: FineVision Toric
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IgY Efficacy on Periodontitis Patients
Status: COMPLETED
Conditions: Chronic Periodontitis
Interventions: DIETARY_SUPPLEMENT: lozenges containing IgY|DIETARY_SUPPLEMENT: Placebo IgY
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Preoperative Estrogen Treatment on Connective Tissues of the Pelvic Floor
Status: COMPLETED
Conditions: Pelvic Organ Prolapse|Menopause
Interventions: DRUG: Premarin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phase I Study of Safety and Pharmacokinetics of Topical Solution in Subjects With Androgenetic Alopecia
Status: NOT_YET_RECRUITING
Conditions: Androgenetic Alopecia
Interventions: DRUG: Minoxidil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of dmLT ID Vaccination in Healthy Adults
Status: COMPLETED
Conditions: Gastroenteritis Escherichia Coli
Interventions: OTHER: Placebo|BIOLOGICAL: Recombinant Double Mutant Heat-Labile Toxin LT(R192G/L211A) (dmLT) Oral enterotoxigenic Escherichia coli (ETEC) Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis
Status: UNKNOWN
Conditions: Leptomeningeal Metastasis
Interventions: DRUG: Pemetrexed|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chinese Validation of the Simplified Evaluation of CONsciousness Disorders（SECONDs）
Status: COMPLETED
Conditions: Brain Diseases|Vegetative State|Unconsciousness|Central Nervous System Diseases
Interventions: DIAGNOSTIC_TEST: Simplified Evaluation of CONsciousness Disorders (SECONDs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety Study Comparing CPL409116 to Placebo in Participants With Active Rheumatoid Arthritis
Status: RECRUITING
Conditions: Rheumatoid Arthritis
Interventions: DRUG: CPL409116|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Respiratory Training on Respiratory and Functional Performance in Patients With Stroke
Status: UNKNOWN
Conditions: Stroke
Interventions: OTHER: respiratory training.|OTHER: sham training.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation
Status: COMPLETED
Conditions: Neuroma|Neuroma Amputation|Pain
Interventions: PROCEDURE: Targeted Muscle Reinnervation|PROCEDURE: Traction Neurectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect Kinesio Taping on Acute-onset Muscle Soreness and Calf Muscle Extensibility Among Endurance Athletes
Status: COMPLETED
Conditions: Muscle Soreness
Interventions: OTHER: Kinesio Taping|OTHER: Sham Taping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?
Status: TERMINATED
Conditions: Depression
Interventions: DRUG: Diazoxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MCAF and EMD With and Without CTG Wall Technique for the Treatment of Class III and IV Gingival recessions-a Randomized Control Trial
Status: RECRUITING
Conditions: Gingival Recession
Interventions: PROCEDURE: Connective tissue graft wall technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
Status: COMPLETED
Conditions: Periodontal Diseases|Smoking Cessation
Interventions: PROCEDURE: Minimally invasive non-surgical periodontal therapy|PROCEDURE: Conventional non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Contribution of an Artificial Intelligence Tool to Help the Diagnosis of Limb Fractures in Pediatric Emergencies
Status: RECRUITING
Conditions: Fractures, Bone
Interventions: DIAGNOSTIC_TEST: radiograph interpretation without the support of the RAYVOLVE app|DIAGNOSTIC_TEST: radiograph interpretation with the support of the RAYVOLVE app
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class Patients
Status: UNKNOWN
Conditions: Noninvasive Ventilation|Respiratory Insufficiency|Deep Sedation|Hypoxia|Airway Management|Colonoscopy
Interventions: DEVICE: high-flow nasal oxygenation (HFNO)|DEVICE: low-flow nasal oxygenation (LFNO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wharton´s Jelly Derived Mesenchymal Stromal Cell Treatment of Adult Patients Diagnosed With Type I Diabetes
Status: COMPLETED
Conditions: Type1 Diabetes Mellitus
Interventions: DRUG: ProTrans: Allogeneic transplantation with WJMSCs|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Energy Density on Liking and on Caloric Adjustment Conditioning
Status: COMPLETED
Conditions: Conditioning of Caloric Adjustment and Liking in Children
Interventions: BEHAVIORAL: 2 exposures arm|BEHAVIORAL: 7 exposures arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effects of Comprehensive Postoperative Pulmonary Tele-Rehabilitation in Elderly Patients With Resectable Lung Cancer
Status: COMPLETED
Conditions: Telerehabilitation|Carcinoma, Non-Small-Cell Lung|Cardiopulmonary Exercise Test
Interventions: OTHER: Pulmonary Tele-Rehabilitation|OTHER: Control (Education)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy
Status: COMPLETED
Conditions: Ventilator-Induced Lung Injury|Inflammatory Response|Respiratory Complication
Interventions: OTHER: Conventional One-Lung Ventilation|OTHER: Protective One-lung ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Long-Term Lithium Treatment for Aggressive Conduct Disorder
Status: COMPLETED
Conditions: Conduct Disorder|Aggression
Interventions: DRUG: Lithium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study to Evaluate the Safety and Efficacy of TAK-385, Together With a Leuprorelin Observational Cohort, in Participants With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Relugolix|DRUG: Leuprorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder
Status: COMPLETED
Conditions: Tourette Syndrome|Tic Disorders
Interventions: BEHAVIORAL: Habit reversal therapy|BEHAVIORAL: Supportive therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Renal Denervation on Atrial Fibrillation
Status: UNKNOWN
Conditions: Arterial Hypertension|Atrial Fibrillation
Interventions: PROCEDURE: Sympathetic Renal Denervation|DEVICE: Implantable Loop Recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of the Safety and Effectiveness of Combination Anti-HIV Therapy in HIV-Infected Adults
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Abacavir sulfate, Lamivudine and Zidovudine|DRUG: Lamivudine/Zidovudine|DRUG: Abacavir sulfate|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Prevalence of Lysosomal Hydrolase Alpha-glagtosidase Deficiency in Patients With Antiphospholipid Syndrome.
Status: UNKNOWN
Conditions: Antiphospholipid Syndrome
Interventions: DIAGNOSTIC_TEST: antiphospholipid syndrome
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Prothrombotic Factors and Anaesthesia in Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Cancer|Surgery
Interventions: DRUG: Propofol|DRUG: remifentanyl|DRUG: Midazolam|DRUG: Fentanyl|DRUG: Sevoflurane
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk
Status: COMPLETED
Conditions: Depression|Major Depressive Disorder|Dysthymic Disorder|Depressive Symptoms|Type 2 Diabetes|PreDiabetes|Insulin Resistance
Interventions: BEHAVIORAL: Good Days Ahead (GDA)|BEHAVIORAL: Problem Solving Treatment in Primary Care (PST-PC)|DRUG: Antidepressant Medications|OTHER: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary Dysplasia
Status: COMPLETED
Conditions: Infant, Premature, Diseases|Respiratory Distress Syndrome, Newborn|Bronchopulmonary Dysplasia
Interventions: DRUG: Curosurf|OTHER: Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT