pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Comparison of Three Methods of Hemoglobin Monitoring in Pediatric Patients
Status: UNKNOWN
Conditions: Child
Interventions: DEVICE: blood measurement|DEVICE: pulse co-oxymeter (SpHb)|DEVICE: hemoCue
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Soy Fiber Improves Weight Loss and Lipid Profile
Status: COMPLETED
Conditions: Obesity|Overweight|Weight Loss
Interventions: DIETARY_SUPPLEMENT: biscuits supplemented with soy fiber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy
Status: COMPLETED
Conditions: Acute Postoperative Pain|Bunionectomy
Interventions: DRUG: ACP-044 Dose A|DRUG: ACP-044 Dose B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Duchenne Muscular Dystrophy
Status: UNKNOWN
Conditions: Duchenne Muscular Dystrophy
Interventions: BIOLOGICAL: human umbilical cord mesenchymal stem cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Heart Safety Study of Ondansetron in Children Receiving Chemotherapy
Status: WITHDRAWN
Conditions: Malignant Childhood Neoplasm
Interventions: DRUG: Ondansetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM)
Status: RECRUITING
Conditions: ANCA Associated Vasculitis
Interventions: DRUG: Telitacicept|OTHER: Placebo of Telitacicept
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomised Open Label Study of Insulin Degludec Versus Insulin Glargine U100 in Ramadan
Status: TERMINATED
Conditions: Type2 Diabetes
Interventions: DRUG: Insulin Degludec U100|DRUG: Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Nerve Function After Mandible Surgery With a Modified Bilateral Sagittal Split Osteotomy Technique
Status: COMPLETED
Conditions: Neurosensory Function of Inferior Alveolar Nerve
Interventions: PROCEDURE: bilateral sagittal split osteotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Acute Phase Markers and Post-operative Pain in Open Tension-free Inguinal Hernia Repair: An Observational Study
Status: RECRUITING
Conditions: Post Operative Pain|Inguinal Hernia
Interventions: PROCEDURE: Open Tension-free Inguinal Hernia Repair
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tele-rehabilitation in Children With Cerebral Palsy in the Covid-19 Pandemic
Status: UNKNOWN
Conditions: Cerebral Palsy|Telerehabilitation|Motor Learning
Interventions: OTHER: Telerehabilitation İntervention, Motor learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-Idiopathic Scoliosis Treated With Tranexamic Acid
Status: TERMINATED
Conditions: Non-idiopathic Scoliosis
Interventions: DRUG: Tranexamic acid 10mg/kg/hr|DRUG: Tranexamic acid 100 mg/kg/h infusion|DRUG: Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Therapeutic Measures of Tdcs in Patients With Refractory Focal Epilepsy
Status: COMPLETED
Conditions: Refractory Epilepsy
Interventions: DEVICE: Cathodal Transcranial Direct Current Stimulation (tDCS).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium
Status: WITHDRAWN
Conditions: Vitamin D Deficiency|Nephrolithiasis
Interventions: DRUG: vitamin D (ergocalciferol)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: G.I. Pharmacokinetics of LMN-401 in Individuals With Ileostomies
Status: NOT_YET_RECRUITING
Conditions: Travelers Diarrhea
Interventions: BIOLOGICAL: LMN-401
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Hypnosis in Pain Management, Anxiety and Depression in Oncological Patients
Status: COMPLETED
Conditions: Pain|Depression Anxiety Disorder
Interventions: BEHAVIORAL: Hypnosis|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Harmonic ACE®+7 Shears in Laparoscopic Hysterectomy
Status: COMPLETED
Conditions: Benign Disease Where Total Hysterectomy is Indicated
Interventions: DEVICE: Harmonic ACE®+7 Shears
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Yttrium Y 90 Anti-CD19 Antibody BU-12 in Patients With Advanced Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia
Interventions: RADIATION: yttrium Y 90 anti-CD19 monoclonal antibody BU12|RADIATION: 111In-BU-12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Short Term, High Dose Atorvastatin Therapy on Periprocedural Myonecrosis and Platelet Inhibition After Percutaneous Coronary Intervention (PCI)
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Flex-it® to the GlideRite® Stylet for GlideScope® in Simulated Difficult Intubations.
Status: UNKNOWN
Conditions: Difficult Intubation
Interventions: DEVICE: GlideScope® intubation with Flex-it® stylet|DEVICE: GlideScope® intubation with GRS® stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Rituximab and Chemotherapy Followed by Ibritumomab Tiuxetan as Treatment for Low Grade Follicular Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Non-Hodgkins Lymphoma
Interventions: DRUG: Rituximab|DRUG: CHOP|DRUG: CVP|DRUG: Ibritumomab Tiuxetan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Deep Neuromuscular Block on the Perioperative Stress Response Reduction and Postoperative Recovery Enhancement in Robot-assisted Stomach Cancer Surgery
Status: COMPLETED
Conditions: Stomach Cancer
Interventions: DRUG: Deep neuromuscular block with 'rocunium®'|DRUG: Moderate neuromuscular block with 'rocunium®'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose-parallel-group Study of AMA0076 in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma|Ocular Hypertension|Eye Disease
Interventions: DRUG: AMA0076|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Collection of Patient-Reported Symptoms and Performance Status Via the Internet
Status: COMPLETED
Conditions: Prostate Cancer|Breast Cancer|Lung Cancer|Colorectal Cancer|Leukemia|Multiple Myeloma
Interventions: OTHER: internet-based intervention|OTHER: assessment of therapy complications|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Patient Preferences in Making Treatment Decisions in Patients With Stage I-IVA Oropharyngeal Cancer
Status: TERMINATED
Conditions: Stage I Squamous Cell Carcinoma of the Oropharynx|Stage II Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage IVA Squamous Cell Carcinoma of the Oropharynx|Tongue Cancer
Interventions: OTHER: questionnaire administration|PROCEDURE: quality-of-life assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Optical Properties of Light Cured Luting Agent on Laminate Veneer
Status: COMPLETED
Conditions: Optical Properties of Laminate Veneers
Interventions: PROCEDURE: Laminate veneers luted with light-cured resin cement|PROCEDURE: Laminate veneers luted with light-cured flowable composite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Caloric Restriction and Exercise on Body Weight, Immune Function, and Intestinal Flora
Status: COMPLETED
Conditions: Cardiometabolic Risk|Weight Loss|Immune System|Intestinal Microbiome
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: Caloric restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Learn About How Itraconazole Affects the Blood Level of Study Medicine (PF-07817883) in Healthy Adults.
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: PF-07817883|DRUG: Itraconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin C Chewing Gum, Pregnancy Nausea and Vomiting
Status: RECRUITING
Conditions: Pregnancy Nausea and Vomiting
Interventions: OTHER: Chewing gum with vitamin C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Study of Regorafenib and Nivolumab Plus Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Adenocarcinoma|Gastroesophageal Junction Adenocarcinoma|Esophageal Adenocarcinoma
Interventions: DRUG: Regorafenib|DRUG: Nivolumab|DRUG: CapeOX|DRUG: FOLFOX regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Engerix™-B in Adults With or Without Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Hepatitis B
Interventions: BIOLOGICAL: Engerix™-B vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
Status: COMPLETED
Conditions: Pancreatic Neoplasm
Interventions: DEVICE: EUS guided FNA and fine needle punction
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: ADO09 formulation|DRUG: Placebo|DRUG: Symlin®|DRUG: Humulin®|DRUG: Humalog®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Using Novel Markers to Predict Malignancy in Elevated-Risk Women
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: PROCEDURE: CA125 assay on Abbott Architect i1000SR platform|PROCEDURE: HE4 assay on Architect i1000SR platform|PROCEDURE: Transvaginal Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Gabapentin and Chronic Post Surgical Pain
Status: WITHDRAWN
Conditions: Pain, Postoperative|Scoliosis Idiopathic
Interventions: DRUG: Gabapentin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Peer-Guided Pilates Exercise on Premenstrual Syndrome Symptoms and Healthy Lifestyle Behaviors: A Randomized Controlled Study
Status: COMPLETED
Conditions: Premenstrual Syndrome
Interventions: BEHAVIORAL: Pilates Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation
Status: COMPLETED
Conditions: Intervertebral Disk Degeneration
Interventions: DEVICE: P-15 Synthetic osteoconductive bone substitute|OTHER: Autologous bone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Local and Intravenous Dexamethasone on Post Operative Pain a After CS
Status: COMPLETED
Conditions: Postoperative Pain
Interventions: DRUG: Dexamethasone|DRUG: Dexamethasone|DRUG: Saline (IV fluids)|DRUG: Bupivicaine and Fentany|DEVICE: 25G spinal needles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reproducibility of an Immobilization Device (BodyFIX) - Hodgkins/Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Disease|Lymphoma, Non-Hodgkin
Interventions: DEVICE: BodyFIX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Ultrasound-Guided Classic And Lateral Approach Thoracolumbar Interfascial Plane Block
Status: COMPLETED
Conditions: Lumbar Disc Herniation
Interventions: OTHER: Classic block (Group C) and modified block (Group M) groups
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PNF Exercises on Treatment of Temporomandibular Dysfunction
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders
Interventions: OTHER: proprioceptive neuromuscular facilitation exercises|OTHER: traditional physical therapy treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quercetin's Effect on Bone Health and Inflammatory Markers
Status: COMPLETED
Conditions: Osteoporosis, Postmenopausal
Interventions: DIETARY_SUPPLEMENT: Quercetin (500 mg)|OTHER: Placebo (500 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy
Status: COMPLETED
Conditions: Vitrectomy Operation Under General Anesthesia
Interventions: DRUG: fresofol and remifentanil|DRUG: desflurane and remifentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.
Status: RECRUITING
Conditions: Chronic Hepatitis b
Interventions: DRUG: AB-101|DRUG: Placebo|DRUG: Nucleos(t)ide Analogue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: ULTRA-LAP Trial: Laparoscopic Debulking Surgery (LDS) in Advanced Ovarian Cancer
Status: RECRUITING
Conditions: Ovarian Cancer
Interventions: PROCEDURE: Laparoscopic Debulking Surgery in advanced ovarian cancer|PROCEDURE: Standard laparotomic Debulking Surgery in advanced ovarian cancer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gastrostomy Tube Placed After Gastropexy Versus Gastrostomy Tube Placed Using the Traditional Push/Pull Techniques
Status: COMPLETED
Conditions: Gastrostomy, Methods
Interventions: DEVICE: A 20 Fr gastrostomy tube, placed using push/pull techniques.|DEVICE: A 20 Fr balloon type tube, placed after gastropexy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Hypoglycemic Effect of Cyclocarya Paliurus Extract on Hyperglycemic Populations
Status: UNKNOWN
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Cyclocarya paliurus extract|DIETARY_SUPPLEMENT: Cyclocarya paliurus compounds|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST)
Status: TERMINATED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: Masitinib|DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of OmegaBoost to Increase Omega-3 Levels in Healthy Individuals
Status: ACTIVE_NOT_RECRUITING
Conditions: Dry Eye Syndromes|Age-Related Macular Degeneration|Omega 3 Index
Interventions: DIETARY_SUPPLEMENT: OmegaBoost|DIETARY_SUPPLEMENT: Nature Made (soft gel)|DIETARY_SUPPLEMENT: Nature Made (gummy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
Status: COMPLETED
Conditions: Constipation|Diarrhea|Indigestion|Reflux|Abdominal Pain
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Lactobacillus reuteri DSM 17938
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PRJ2203: Dolutegravir Post Authorization Safety Study (PASS)
Status: COMPLETED
Conditions: Infection, Human Immunodeficiency Virus I
Interventions: DRUG: DTG based ARV regimen with ABC|DRUG: DTG based ARV regimen without ABC|DRUG: RAL or EGV based ARV regimens with ABC|DRUG: RAL or EGV based regimens without ABC|DRUG: Any other DTG based ARV regimen as monotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Clinical Characteristics, Outcomes and Risk Factors for Mortality in Pregnant/Puerperal Women With COVID-19 Admitted to ICU in Turkey: a Multicenter, Retrospective Study From a Middle-income Country.
Status: COMPLETED
Conditions: Key Words:COVID-19; Pregnancy; Intensive Care Unit; SARS-CoV-2; Mortality
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of CD19-BCMA Targeted CAR-T Therapy for Refractory Generalized Myasthenia Gravis
Status: RECRUITING
Conditions: Myasthenia Gravis
Interventions: DRUG: CD19-BCMA Targeted CAR-T Dose 1|DRUG: CD19-BCMA Targeted CAR-T Dose 2|DRUG: CD19-BCMA Targeted CAR-T Dose 2
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Ibuprofen Versus Placebo in Treatment of Patent Ductus Arteriosus (PDA)in Preterm Infants
Status: COMPLETED
Conditions: Patent Ductus Arteriosus After Premature Birth|Patent Ductus Arteriosus Conservative Management
Interventions: DRUG: Ibuprofen oral suspension|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the Predictive Value of TREM1 Expression and Activation in Inflammation and Radio-induced Mammary Fibrosis
Status: RECRUITING
Conditions: Radiation Toxicity|Fibrosis|Breast Cancer
Interventions: BIOLOGICAL: Blood sampling
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Idiotypic Vaccination for Follicular Lymphoma Patients
Status: UNKNOWN
Conditions: Follicular Lymphoma|First Relapse/Progression
Interventions: BIOLOGICAL: Follicular lymphoma, patient-specific, soluble protein idiotype vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Applications in Biliary Atresia Patients
Status: RECRUITING
Conditions: Biliary Atresia|Fibrosis, Liver|Stem Cell
Interventions: DRUG: Stem Cell|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of tDNA Care on Weight Loss and Metabolic Outcomes in Patients With Overweight, Obesity and Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Obesity
Interventions: OTHER: tDNA-MI group|OTHER: tDNA-CC group|OTHER: UC group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Three-month Clinical Evaluation of DSiHy Daily Disposable Silicone Hydrogel Contact Lenses
Status: UNKNOWN
Conditions: Contact Lenses
Interventions: DEVICE: DSiHy Silicone hydrogel soft contact lens|DEVICE: CE-marked Silicone hydrogel soft contact lens
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Randomized Clinical Trial Comparing Conventional Laparoscopic Surgery and Robot-Assisted Laparoscopic Surgery for the Treatment of Parastomal Hernia of the Oncology Patient
Status: UNKNOWN
Conditions: Parastomal Hernia|Oncology
Interventions: PROCEDURE: Robot Assisted Laparoscopic Surgery for the Treatment of Parastomal Hernia|PROCEDURE: Laparoscopic Surgery for the Treatment of Parastomal Hernia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Change in Atherosclerotic Plaque by Serial CCTA
Status: UNKNOWN
Conditions: Coronary Artery Disease|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Coronary Arteriosclerosis
Interventions: DRUG: Atorvastatin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect Of Combination of Morphine+Fentanyl on Emergence Delirium in Patients of Cleft Lip and Palate Repair
Status: COMPLETED
Conditions: Anesthesia Emergence Delirium
Interventions: DRUG: MORPHINE PLUS FENTANYL|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly
Status: ACTIVE_NOT_RECRUITING
Conditions: Acromegaly
Interventions: DRUG: Paltusotine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Randomized Trial of Two Ablation Catheters in Paroxysmal Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DEVICE: WACA and PVI|DEVICE: PVAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bowel Function After Laparoscopic Colon Surgery: Effect of IV Lidocaine
Status: COMPLETED
Conditions: Colon Cancer|Inflammatory Bowel Diseases|Diverticulitis
Interventions: DRUG: Lidocaine|PROCEDURE: Thoracic epidural block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Use Therapeutic Chinese Massage to Treat Peripheral Neuropathy in People With HIV
Status: UNKNOWN
Conditions: Peripheral Neuropathy
Interventions: BEHAVIORAL: Three Weekly Therapeutic Chinese Massage Sessions|BEHAVIORAL: Three Weekly Placebo Massage Sessions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous Insufficiency
Status: RECRUITING
Conditions: Chronic Venous Insufficiency
Interventions: DEVICE: Sigvaris Compreflex Inelastic Compression Wrap
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palbociclib + Letrozole Versus Epirubicin + Cyclophosphamide and Sequential Docetaxel as Neoadjuvant Chemotherapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: palbociclib combined with letrozole|DRUG: epirubicin combined with cyclophosphamide and sequential docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gamma Induction for Alzheimer's Disease
Status: RECRUITING
Conditions: Alzheimer Disease|Mild Cognitive Impairment
Interventions: DEVICE: Transcranial Alternating Current Stimulation (tACS)|OTHER: Sham Transcranial Alternating Current Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: In Vivo Kinematics of Scapolunate Interosseous Ligament Injuries
Status: TERMINATED
Conditions: Scapholunate Ligament Tear
Interventions: DEVICE: CT scan|DEVICE: Fluoroscopy Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Potassium Binder in CKD Patients (With Hyperkalemia) (DiPo Trial)
Status: UNKNOWN
Conditions: Chronic Kidney Diseases|Hyperkalemia
Interventions: DRUG: Sodium Zirconium Cyclosilicate Oral Product
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the DragonFly-T System for Severe Tricuspid Regurgitation
Status: RECRUITING
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: DragonFly-T Transcatheter Tricuspid Valve Repair System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug Repurposing - Statins as Microbiota Modulating Agents in Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Rosuvastatin 10mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Apico-coronal Position of the Implant in Edentulous Diabetics With Implant-retained Overdentures
Status: COMPLETED
Conditions: Diabetes Mellitus|Dental Implants
Interventions: DEVICE: Dental Implant Placement and subsequent prosthetic reabilithation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab, Docetaxel, and Radiation Therapy in Treating Patients With Stage III or Stage IV Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: BIOLOGICAL: bevacizumab|DRUG: docetaxel|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcomes of Three Corner Fusion Without Triquetrum Excision Versus Conventional Four Corner Fusion in SNAC Wrist
Status: COMPLETED
Conditions: Scaphoid Fracture
Interventions: PROCEDURE: Four corner fusion|PROCEDURE: three corner fusion without triquetrum excision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Leuprolide acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preventing Alcohol Withdrawal Syndrome With Oral Baclofen
Status: TERMINATED
Conditions: Alcohol Withdrawal Syndrome
Interventions: DRUG: Baclofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Double-blind and Randomized Trial of Celecoxib Added to Risperidone in Treatment-naive First-episode Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: celecoxib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Premature Family Music Therapy Intervention (PFMI)
Status: UNKNOWN
Conditions: Music Therapy
Interventions: OTHER: Premature family music therapy intervention to support parenting, attachment bond and preterm development
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Local Infiltration Analgesia With Ropivacaine Versus Placebo in Caesarean Section
Status: COMPLETED
Conditions: Pain, Postoperative|Postoperative Nausea and Vomiting|Cesarean Section
Interventions: DRUG: Ropivacaine|DRUG: Ropivacaine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Improved Cardiovascular Health for Patients With Inflammatory Joint Diseases
Status: COMPLETED
Conditions: Spondyloarthritis|Rheumatoid Arthritis|Psoriatic Arthritis
Interventions: BEHAVIORAL: High-intensity exercise (HIIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effect of Lipikar Baume AP+M
Status: NOT_YET_RECRUITING
Conditions: Actinic Keratoses
Interventions: OTHER: Lipikar Baume AP+M
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Standardization of CD3+ T Cell Dose for Patients Receiving Allogeneic Peripheral Blood Stem Cell Transplantation From Matched Related Donors
Status: ACTIVE_NOT_RECRUITING
Conditions: Hematopoietic Stem Cell Transplantation
Interventions: DEVICE: CD3+ T cell depletion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders
Status: COMPLETED
Conditions: Depression|Anxiety|Eating Disorders|Drug Use Disorders
Interventions: BEHAVIORAL: standardized diagnostic assessment|BEHAVIORAL: self-report questionnaires|BEHAVIORAL: behavioral tasks|OTHER: physiological measurements|OTHER: structural and functional magnetic resonance imaging and EEG|OTHER: biomarker and microbiome assessments|OTHER: blood to derive induced pluripotent stem cells|OTHER: genetic and epigenetic assessments
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Optical Quality With Different Placement of Refractive Multifocal Intraocular Lens
Status: COMPLETED
Conditions: Cataract, Age-Related
Interventions: PROCEDURE: angle kappa based SBL-3 implantation|PROCEDURE: 0 to 180 degree SBL-3 implantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Only Mesh Fixation With Glue of Ventral/Incisional Laparoscopic Hernia Repair
Status: NOT_YET_RECRUITING
Conditions: Ventral Incisional Hernia
Interventions: DEVICE: Glutack|DEVICE: Conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma.
Status: ACTIVE_NOT_RECRUITING
Conditions: Melasma
Interventions: COMBINATION_PRODUCT: TAM formula (hydroquinone 2%, tretinoin 0.05% and 5% vitamin C)|COMBINATION_PRODUCT: Kligman formula (hydroquinone 4%, fluocinolone acetonide 0.01% and tretinoin 0.05%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Maxillary Molar Distalization With Two Bone Supported Protocols Using Cone Beam Computed Tomography
Status: ACTIVE_NOT_RECRUITING
Conditions: Class II Malocclusion
Interventions: DEVICE: Insertion of the device intraorally
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis
Status: UNKNOWN
Conditions: Periapical Diseases
Interventions: DRUG: Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste|DRUG: creosote
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies
Status: RECRUITING
Conditions: Ovarian Cancer|Clear Cell Carcinoma|Endometrial Cancer|Cervical Carcinoma|Metastatic Castration-Resistant Prostate Cancer (mCRPC)
Interventions: BIOLOGICAL: vudalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study
Status: COMPLETED
Conditions: Pre-Eclampsia|Hypertension, Pregnancy-Induced
Interventions: OTHER: Self-management of postnatal anti-hypertensive treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CM082 Combined With Everolimus in Chinese Patients With Metastatic Renal Cell Carcinoma
Status: UNKNOWN
Conditions: Renal Cell Cancer Metastatic
Interventions: DRUG: CM082 combined with everolimus|DRUG: CM082|DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment
Status: NOT_YET_RECRUITING
Conditions: Cannabis Intoxication|Alcohol Intoxication
Interventions: DRUG: Cannabis|DRUG: Alcohol|DRUG: Placebo Cannabis|DRUG: Placebo Alcohol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus
Status: RECRUITING
Conditions: Diabetes Mellitus|Coronary Artery Disease|Acute Coronary Syndrome
Interventions: DEVICE: Abluminus Sirolimus Eluting Stent System (ASES)|DEVICE: Orsiro Sirolimus Eluting Coronary Stent System (OSES)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)
Status: COMPLETED
Conditions: Cancer|Pediatric Solid Tumor|Pediatric AML|Pediatric ALL
Interventions: DRUG: PEG- BCT-100
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Melatonin on Reduction of Pelvic Pain
Status: COMPLETED
Conditions: Dysmenorrhea|Endometriosis
Interventions: DRUG: Melatonin 10 mg|DRUG: Placebo|DRUG: Melatonin 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Characterization of the Microbiome in Peritoneum, Jejunum, Rectum and Stool
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity|Diabetes Mellitus|Fatty Liver, Nonalcoholic|Leaky Gut Syndrome|Chronic Pancreatitis
Interventions: DIAGNOSTIC_TEST: Microbial Swab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: At-Home Telehealth Yoga for Treating Chronic Pain in People With Alzheimer's Disease and Their Caregiver's
Status: COMPLETED
Conditions: Alzheimer Disease|Musculoskeletal Pain|Chronic Pain
Interventions: BEHAVIORAL: At-Home Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study
Status: UNKNOWN
Conditions: Hyperoxia|Cardiac Surgery|Cardiopulmonary Bypass|Acute Lung Injury|Oxygen Toxicity
Interventions: DRUG: Oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: anastrozole|DRUG: simvastatin|OTHER: pharmacological study|PROCEDURE: adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bank of Human Leukocytes From COVID-19 Convalescent Donors With an Anti-SARS-CoV-2 Cellular Immunity
Status: RECRUITING
Conditions: COVID-19
Interventions: OTHER: Generation of a biobank allowing the cryopreservation of leucocytes from COVID19 convalescent donors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vertical Gingival Display Changes Associated With Upper Premolars Extraction
Status: COMPLETED
Conditions: Gummy Smile|Orthodontic Treatment
Interventions: PROCEDURE: Upper first premolars extractions|PROCEDURE: Upper second premolars extraction
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Protein Patterns for Skeletal Muscle Preservation and Sleep in the Medical Management of Parkinson Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: BEHAVIORAL: Protein Redistribution Diet|BEHAVIORAL: Protein Consistent Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: AZD1775 in Women With Recurrent or Persistent Uterine Serous Carcinoma or Uterine Carcinosarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Uterine Cancer
Interventions: DRUG: AZD1775
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Genicular Arteries Embolization in Symptomatic Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: Ethiodized Oil-based emulsion|PROCEDURE: Sham-operation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Dose Escalation Study of RO6874813 in Participants With Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: BIOLOGICAL: RO6874813|BIOLOGICAL: RO6874813
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Percutaneous Radiofrequency Ablation of Feeding Arterial for Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Liver Neoplasms
Interventions: OTHER: PAFA|OTHER: tumor ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Pharmacist-guided Digital-based Asthma Education for Indonesian Children With Asthma
Status: UNKNOWN
Conditions: Asthma in Children|Asthma Chronic|Asthma
Interventions: BEHAVIORAL: The digital asthma education program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Neurobiological Bases of Placebo Response in Major Depressive Disorder
Status: TERMINATED
Conditions: Major Depressive Disorder
Interventions: DRUG: Escitalopram 10mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-Intensity Mechanical Stimulation for Hematologic Malignancy Patients
Status: RECRUITING
Conditions: Hematopoietic and Lymphoid System Neoplasm
Interventions: PROCEDURE: Low Intensity Vibration Therapy|PROCEDURE: Dual X-ray Absorptiometry|PROCEDURE: Biospecimen Collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Ketamine in the Acute Phase of Suicidal Ideation
Status: COMPLETED
Conditions: Suicidal Ideation
Interventions: OTHER: Baseline evaluation|DRUG: 1st perfusion of ketamine|DRUG: 1st perfusion of saline|OTHER: Follow-up between perfusions|DRUG: 2nd perfusion of ketamine|DRUG: 2nd perfusion of saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Transverse Abdominis Plane Block for Anterior Approach Spine Surgery
Status: COMPLETED
Conditions: Spine Surgery|Low Back Pain|Spondylolisthesis
Interventions: DRUG: TAP block ropivacaine|DRUG: TAP block placebo|DRUG: General anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate DT-216 in Adult Patients With Friedreich Ataxia
Status: COMPLETED
Conditions: Friedreich Ataxia
Interventions: DRUG: DT-216|DRUG: DT-216 matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological Malignancies
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma
Interventions: DRUG: BMN 673
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimize Study - Orelabrutinib Combined With BR/G in Untreated Marginal Zone Lymphoma (MZL)
Status: RECRUITING
Conditions: Marginal Zone Lymphoma
Interventions: DRUG: Orelabrutinib combined with bendamustine and rituximab|DRUG: Orelabrutinib combined with obinutuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chordal Repair for Transcatheter Mitral Valve Repair (TMVr)
Status: ACTIVE_NOT_RECRUITING
Conditions: Degenerative Mitral Valve Disease|Mitral Valve Regurgitation
Interventions: DEVICE: Transcatheter implantation of chordal repair system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
Status: NOT_YET_RECRUITING
Conditions: Multiple Sclerosis|Hypertension
Interventions: BEHAVIORAL: Home-based aerobic training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Directed Use of REmote Patient Management System AMia to Achieve Prescribed Dry Weight
Status: ACTIVE_NOT_RECRUITING
Conditions: Efficacy|Safety Issues
Interventions: COMBINATION_PRODUCT: AMIA with SHARESOURCE Connectivity Platform|DEVICE: HomeChoice PRO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motion Sifnos: A Study to Investigate the Efficacy of Tradipitant in Subjects Affected by Motion Sickness
Status: COMPLETED
Conditions: Motion Sickness
Interventions: DRUG: Tradipitant|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT