pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Assessing Metabolic and Sleep Consequences of Overnight Home Parenteral Nutrition
Status: COMPLETED
Conditions: Feeding Patterns|Sleep|Glucose Intolerance|Short Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Time-of-day of parenteral nutrition provision
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Intermittent Moxifloxacin Therapy For The Prevention Of Acute Exacerbations In Patients With Chronic Bronchitis
Status: COMPLETED
Conditions: Lung Diseases|Bronchitis, Chronic
Interventions: DRUG: Avelox (Moxifloxacin, BAY12-8039)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Belantamab Mafodotin In Plasmablastic Lymphoma & ALK+ Large B-Cell Lymphoma
Status: RECRUITING
Conditions: Relapsed Plasmablastic Lymphoma|Refractory Plasmablastic Lymphoma|Anaplastic Lymphoma Kinase Positive Large B-Cell Lymphoma
Interventions: DRUG: Belantamab Mafodotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures
Status: TERMINATED
Conditions: Arthroscopy|Bunionectomy|Osteotomy|Carpal Tunnel
Interventions: DRUG: fospropofol disodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Therapeutic Touch and Reiki Application on Anxiety and Stress Levels in Female Academicians
Status: NOT_YET_RECRUITING
Conditions: Stress|Anxiety
Interventions: OTHER: THERAPEUTIC TOUCH|OTHER: REİKİ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Phase I Pharmacokinetics Study for KT07 Capsule
Status: COMPLETED
Conditions: Healthy Adult Subjects|Pharmacokinetics|Safety and Tolerability
Interventions: DRUG: Low dose KT07|DRUG: High dose KT07|DRUG: Low dose Placebo|DRUG: High dose Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Post-Marketing Surveillance Study to Assess Safety of Luspatercept in Korean Patients With Myelodysplastic Syndrome or β-thalassemia
Status: RECRUITING
Conditions: Myelodysplastic Syndrome|Beta Thalassemia
Interventions: DRUG: Luspatercept
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax
Status: UNKNOWN
Conditions: Spontaneous Pneumothorax|Surgery
Interventions: PROCEDURE: Thoracoscopic bullectomy and pleural abrasion|BIOLOGICAL: Mesh coverage of the staple line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Generic Travoprost Versus Brand Name Travoprost in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Glaucoma, Primary Open Angle|Ocular Hypertension
Interventions: DRUG: Brand name travoprost|DRUG: Generic travoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Body Massage Oil, Facial Mask, and Ready-to-drink Jelly From Snake Fruit
Status: COMPLETED
Conditions: Body Massage Oil From Snake Fruit|Facial Mask From Snake Fruit|Jelly From Snake Fruit
Interventions: OTHER: Thai massage, Thai massage with pure coconut oil, Thai massage with oil mixed with Snake fruit extract, Control, Facial mask with Snake fruit extract, Control jelly, Jelly with Snake fruit juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Adjuvant Chemoradiotherapy Followed by Zimberelimab for Locally Advanced Cervical Cancer.
Status: NOT_YET_RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Zimberelimab|DRUG: Platinum|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sildenafil Citrate and Recurrent Abortion
Status: COMPLETED
Conditions: Recurrent Abortion
Interventions: DRUG: Sildenafil Citrate vaginal suppositories|DRUG: Placebo vaginal suppositories|PROCEDURE: Uterine artery Doppler before treatment|PROCEDURE: Uterine artery Doppler after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of AEO in New Glioblastoma (GBM)
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Anhydrous Enol-Oxaloacetate (AEO)|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Banana Blossom on Breast Milk Volume in Mothers of Preterm Newborns
Status: COMPLETED
Conditions: Preterm Birth|Postpartum Women
Interventions: DRUG: Banana Blossom|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of JNJ-66525433 in Healthy Participants and Participants With Ulcerative Colitis
Status: TERMINATED
Conditions: Healthy|Colitis, Ulcerative
Interventions: DRUG: JNJ-66525433|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Bladder Carcinoma|Breast Carcinoma|Cervical Carcinoma|Colon Carcinoma|Colorectal Carcinoma|Endometrial Carcinoma|Esophageal Carcinoma|Exocrine Pancreas Carcinoma|Gastric Carcinoma|Glioma|Head and Neck Carcinoma|Hematopoietic and Lymphoid Cell Neoplasm|Kidney Carcinoma|Liver Carcinoma|Lung Carcinoma|Lymphoma|Malignant Uterine Neoplasm|Melanoma|Multiple Myeloma|Ovarian Carcinoma|Prostate Carcinoma|Rectal Carcinoma|Recurrent Bladder Carcinoma|Recurrent Breast Carcinoma|Recurrent Cervical Carcinoma|Recurrent Colon Carcinoma|Recurrent Colorectal Carcinoma|Recurrent Esophageal Carcinoma|Recurrent Gastric Carcinoma|Recurrent Glioma|Recurrent Head and Neck Carcinoma|Recurrent Liver Carcinoma|Recurrent Lung Carcinoma|Recurrent Lymphoma|Recurrent Malignant Solid Neoplasm|Recurrent Melanoma|Recurrent Multiple Myeloma|Recurrent Ovarian Carcinoma|Recurrent Pancreatic Carcinoma|Recurrent Prostate Carcinoma|Recurrent Rectal Carcinoma|Recurrent Skin Carcinoma|Recurrent Thyroid Gland Carcinoma|Recurrent Uterine Corpus Cancer|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma|Skin Carcinoma|Thyroid Gland Carcinoma|Uterine Corpus Cancer
Interventions: DRUG: Adavosertib|DRUG: Afatinib|DRUG: Afatinib Dimaleate|DRUG: Binimetinib|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|DRUG: Capivasertib|PROCEDURE: Computed Tomography|DRUG: Copanlisib|DRUG: Copanlisib Hydrochloride|DRUG: Crizotinib|OTHER: Cytology Specimen Collection Procedure|DRUG: Dabrafenib|DRUG: Dabrafenib Mesylate|DRUG: Dasatinib|DRUG: Defactinib|DRUG: Defactinib Hydrochloride|PROCEDURE: Echocardiography|DRUG: Erdafitinib|DRUG: Fexagratinib|DRUG: Ipatasertib|OTHER: Laboratory Biomarker Analysis|DRUG: Larotrectinib|DRUG: Larotrectinib Sulfate|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Multigated Acquisition Scan|BIOLOGICAL: Nivolumab|DRUG: Osimertinib|DRUG: Palbociclib|BIOLOGICAL: Pertuzumab|DRUG: PI3K-beta Inhibitor GSK2636771|PROCEDURE: Radiologic Examination|PROCEDURE: Radionuclide Imaging|BIOLOGICAL: Relatlimab|DRUG: Sapanisertib|DRUG: Sunitinib Malate|DRUG: Taselisib|DRUG: Trametinib|BIOLOGICAL: Trastuzumab|BIOLOGICAL: Trastuzumab Emtansine|DRUG: Ulixertinib|DRUG: Vismodegib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide
Status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis (IPF)
Interventions: DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-994 in Adults With Type 1 and Type 2 Narcolepsy
Status: TERMINATED
Conditions: Narcolepsy Type 1 (NT1)|Narcolepsy Type 2 (NT2)
Interventions: DRUG: TAK-994|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contingent Incentives Plus Bupropion for Smoking in People With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia and Disorders With Psychotic Features|Tobacco Use Disorder
Interventions: DRUG: Bupropion|DRUG: Contingent reinforcement plus placebo|DRUG: non-contingent reinforcement plus bupropion|DRUG: Non-contingent reinforcement plus placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Retention and Retrieval for Three Different Training Methods
Status: UNKNOWN
Conditions: Improvement of BLS/AED Training Methods
Interventions: OTHER: ERC-training by instructor|OTHER: Web-based training only|OTHER: Web-based training with a personal training manikin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: French Long Term Registry With Longitudinal Follow up of PDGFRA D842V-GIST Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: GIST|GIST, Malignant|PDGFR-Alpha D842V
Interventions: DRUG: Patient treated by Avapritinib in real life
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Randomised Trial of Expedited Transfer to a Cardiac Arrest Centre for Non-ST Elevation Out-of-hospital Cardiac Arrest
Status: COMPLETED
Conditions: Out-Of-Hospital Cardiac Arrest
Interventions: PROCEDURE: Transfer to cardiac arrest centre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Ketogenic Diet Versus Mediterranean Diet in Patients With Obesity and Psoriatic Arthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Obesity and Psoriasis
Interventions: OTHER: Meditteranean Diet|OTHER: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sunitinib, Cetuximab, and Radiation Therapy in Treating Patients With Locally Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma|Recurrent Metastatic Squamous Neck Cancer With Occult Primary|Recurrent Salivary Gland Cancer|Recurrent Squamous Cell Carcinoma of the Hypopharynx|Recurrent Squamous Cell Carcinoma of the Larynx|Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity|Recurrent Squamous Cell Carcinoma of the Nasopharynx|Recurrent Squamous Cell Carcinoma of the Oropharynx|Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Recurrent Verrucous Carcinoma of the Larynx|Recurrent Verrucous Carcinoma of the Oral Cavity|Salivary Gland Squamous Cell Carcinoma|Stage III Salivary Gland Cancer|Stage III Squamous Cell Carcinoma of the Hypopharynx|Stage III Squamous Cell Carcinoma of the Larynx|Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage III Squamous Cell Carcinoma of the Nasopharynx|Stage III Squamous Cell Carcinoma of the Oropharynx|Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage III Verrucous Carcinoma of the Larynx|Stage III Verrucous Carcinoma of the Oral Cavity|Stage IV Salivary Gland Cancer|Stage IV Squamous Cell Carcinoma of the Hypopharynx|Stage IV Squamous Cell Carcinoma of the Larynx|Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity|Stage IV Squamous Cell Carcinoma of the Nasopharynx|Stage IV Squamous Cell Carcinoma of the Oropharynx|Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity|Stage IV Verrucous Carcinoma of the Larynx|Stage IV Verrucous Carcinoma of the Oral Cavity|Tongue Cancer|Untreated Metastatic Squamous Neck Cancer With Occult Primary
Interventions: DRUG: sunitinib malate|OTHER: pharmacological study|RADIATION: 3-dimensional conformal radiation therapy|BIOLOGICAL: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 111In-DAC as an Medical Imaging Agent for Lung Cancer and Brain Cancer Consistent With Metastatic Lung Cancer
Status: UNKNOWN
Conditions: Lung Neoplasms|Carcinoma, Non-Small-Cell Lung|Brain Neoplasms|Metastases, Neoplasm
Interventions: DRUG: 111In-DAC|PROCEDURE: Diagnostic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pea Protein Oral Nutrition Supplement for the Reduction of Gastrostomy Tube Placement Rate in Patients With Locally Advanced Head and Neck Cancer Undergoing Chemoradiation Therapy
Status: RECRUITING
Conditions: Locally Advanced Head and Neck Carcinoma
Interventions: DIETARY_SUPPLEMENT: Dietary Supplement|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bicentric Prospective Study, Evaluating Bronchial THERMOPLASTY in a Patient Presenting Severe Uncontrolled Asthma
Status: UNKNOWN
Conditions: Asthma
Interventions: DEVICE: ALAIR, radiofrequency catheter for bronchial THERMOPLASTY
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
Status: COMPLETED
Conditions: Hematological Malignancy|Bone Marrow Failure Syndrome
Interventions: DRUG: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders|RADIATION: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders|PROCEDURE: Umbilical Cord Blood Transplantation as Treatment of Adult Patients with Hematologic Disorders
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer
Status: COMPLETED
Conditions: Brain Neoplasms|Lung Neoplasms|Thyroid Neoplasms|Colorectal Neoplasms|Lymphoma
Interventions: PROCEDURE: Positron Emission Tomography (PET) scan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of a Single Preoperative Administration of Action Observation Therapy Associated With Motor Imagery in Patients Undergoing Total Hip Arthroplasty.
Status: COMPLETED
Conditions: Hip Osteoarthritis|Orthopedic Disorder
Interventions: OTHER: Action observation therapy|OTHER: motor imagery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study Between Protopic (Tacrolimus Ointment) and Elidel (Pimecrolimus Cream) in Pediatric Patients With Mild Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: tacrolimus ointment|DRUG: pimecrolimus cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Performance Comparison Between Fanfilcon A and Senofilcon A Sphere Lenses
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: fanfilcon A|DEVICE: senofilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glucose Testing in GDM: Adherence to One- Versus Two-hour Postprandial Glucose Monitoring in Gestational Diabetics
Status: ENROLLING_BY_INVITATION
Conditions: Gestational Diabetes
Interventions: OTHER: 1 hour Blood glucose monitoring|OTHER: 2 hour blood glucose monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion
Status: RECRUITING
Conditions: Adolescent Idiopathic Scoliosis
Interventions: DRUG: Caffeine Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of The Effects of Testosterone in Frail Elderly Men
Status: COMPLETED
Conditions: Frailty|Sarcopenia
Interventions: DRUG: Transdermal testosterone gel (Testogel 1% )|DRUG: Matched transdermal placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Piezoelectric Periodontal Surgery Effects on Orthodontic Treatment: a Prospective Pilot Study
Status: COMPLETED
Conditions: Malocclusion
Interventions: PROCEDURE: Piezocision
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Femtosecond Laser Energy Levels Lead to Better Visual Recovery After Small-incision Lenticule Extraction for Myopia
Status: COMPLETED
Conditions: Myopia
Interventions: PROCEDURE: SMILE procedure using lower energy (100, 105, and 110 nJ)|PROCEDURE: SMILE procedure using conventional energy (115 to 150 nJ)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Radiotherapy According to Molecular Analysis of Surgical Margins of Oral and Oropharyngeal SCC
Status: UNKNOWN
Conditions: Oral Cancer|Oropharynx Cancer
Interventions: PROCEDURE: Radiotherapy 50 Gy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of the Impact on Blood Pressure Control of Supplementing Community Pharmacist Services With Structured Information on Blood Pressure and Its Treatment
Status: COMPLETED
Conditions: Hypertension
Interventions: OTHER: Written and verbal patient education on hypertension and its treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Investigation of a New 2-piece Ostomy Product in People With an Ileostomy or Colostomy
Status: COMPLETED
Conditions: Ileostomy|Colostomy
Interventions: DEVICE: Coloplast Test Product|DEVICE: Comparator (Hollister)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Apremilast in Japanese Pediatric Participants With Moderate to Severe Plaque Psoriasis
Status: RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analysis of Sensory and Motor Thresholds During Transcutaneous Electrical Stimulation in Different Sexes and Ages
Status: COMPLETED
Conditions: Healthy Individuals
Interventions: OTHER: Transcutaneous electrical nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol
Status: COMPLETED
Conditions: Cervical Ripening|Labor Induction
Interventions: DRUG: misoprostol|DRUG: misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ventilation and Pulmonary Aeration, Electrical Impedance Tomography, Interscalene Brachial Plexus Block
Status: UNKNOWN
Conditions: Brachial Plexus Block|Pulmonary Ventilation
Interventions: DRUG: Bupivacaine 4 mL|DRUG: Bupivacaine 15 mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of HR18042 Tablets in the Treatment of Postoperative Pain of Impacted Tooth.
Status: UNKNOWN
Conditions: Moderate to Severe Acute Pain
Interventions: DRUG: HR18042|DRUG: HR18042|DRUG: HR18042|DRUG: Tramadol hydrochloride ER|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: DailyDose Smart Snack Study for T1D on MDI
Status: ACTIVE_NOT_RECRUITING
Conditions: Type 1 Diabetes Mellitus With Hypoglycemia
Interventions: DEVICE: DailyDose Smart Snack app|DEVICE: Dexcom G6 CGM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Pilot/Pharmacodynamic/Genomic Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas
Interventions: DRUG: Paricalcitol|DRUG: Abraxane|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: What is the Best Interval to Screen Women 45-49 and 70-74 for Breast Cancer?
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DIAGNOSTIC_TEST: screening for breast cancer with tomosynthesis and synthetic 2D mammography performed at different interval compared to actual clinical practice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
Status: COMPLETED
Conditions: Facial Rhytides|Crow's Feet Lines|Glabellar Lines
Interventions: BIOLOGICAL: onabotulinumtoxinA 24 U|BIOLOGICAL: onabotulinumtoxinA 44 U|DRUG: normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Determining Whether Intra-Arterial Carboplatin Causes Hearing Loss in Children
Status: ACTIVE_NOT_RECRUITING
Conditions: Intraocular Retinoblastoma|Hearing Loss
Interventions: DIAGNOSTIC_TEST: Distortion product otoacoustic emission measurement (DPOAE)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Effectiveness Study of DragonFly-T System for Severe Tricuspid Regurgitation
Status: RECRUITING
Conditions: Tricuspid Regurgitation
Interventions: DEVICE: DragonFly-T Transcatheter Tricuspid Valve Repair System|DRUG: Medical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Omega-3 Supplementation to Reduce Bronchopulmonary Dysplasia
Status: ACTIVE_NOT_RECRUITING
Conditions: Bronchopulmonary Dysplasia|Child Development|Neonatal and Perinatal Conditions
Interventions: DIETARY_SUPPLEMENT: DHA-rich algal oil|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transferability and Cost-effectiveness of PROSPECT in Surgical Trainees
Status: COMPLETED
Conditions: Vascular Disease
Interventions: OTHER: additional curriculum (E-learning + simulation)|OTHER: additional E-learning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Local, Non-Interventional Study of RoActemra (Tocilizumab) in Poland (ACT-POL): First-Line Treatment in Routine Clinical Practice of Participants With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Tocilizumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Ingenol Mebutate Once Daily for 2 or 3 Consecutive Days in Subjects With Actinic Keratosis
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Ingenol mebutate gel|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Intrathecal Fentanyl and Development of Hyperalgesia in Patients Undergoing Elective Cesarean
Status: UNKNOWN
Conditions: Complications; Cesarean Section
Interventions: DRUG: H-Bupivacaine|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-Term Study Continuing on From Study 04-001-01 of an Experimental Medication in Adults With Anxiety Disorder
Status: COMPLETED
Conditions: Anxiety Disorder
Interventions: DRUG: a benzodiazepine drug
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Immunogenicity of the IHV01 Protein Vaccine Primed and Co-Administered With HIV DNA CON-S Env Vaccine in Healthy, HIV-1-Uninfected Adults
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: BIOLOGICAL: DNA CON-S env|BIOLOGICAL: IHV01|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Restauration of the Auditory and Cognitive Functions in Cochlear Implanted Deaf Children in fNIRS
Status: RECRUITING
Conditions: Deafness
Interventions: DEVICE: Near InfraRed Spectroscopy (fNIRS)|BEHAVIORAL: Passive perceptual stimulation|BEHAVIORAL: Task A not B|BEHAVIORAL: VSWMT task|BEHAVIORAL: Perceptual Go-No-Go|BEHAVIORAL: Verbal memory task|BEHAVIORAL: The sensory room
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer
Status: COMPLETED
Conditions: Metastatic Renal Cell Carcinoma
Interventions: BIOLOGICAL: VEGF Trap
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Low Dose Tadalafil for Treatment of Female OAB Syndrome: Short Term Follow up.
Status: COMPLETED
Conditions: Female Patients With Overactive Bladder Syndrome or Female Patients With Urgency or Urgency Urinary Incontinence
Interventions: DRUG: Low dose tadalafil 5 mg|DRUG: Tolterodine 4 Mg Oral Capsule, Extended Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long Term Follow up of Patients Who Were Treated With Extracorporeal Membrane Oxygenation for Pandemic Influenza A/H1N1 Induced Severe Respiratory Failure
Status: COMPLETED
Conditions: Long Term Outcome
Interventions: RADIATION: CT scan|BEHAVIORAL: Cognitive function|RADIATION: MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss
Status: RECRUITING
Conditions: Postoperative Pain, Acute|Postoperative Depression|Anxiety|Sleep Disturbance|Malignant Female Reproductive System Neoplasm
Interventions: OTHER: eHealth Mindful Movement and Breathing|OTHER: Life Impacts Reflection|OTHER: PROMIS Questionnaires
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pharmacokinetic, Safety and Tolerability Study of Recombinant Von Willebrand Factor / Recombinant Factor VIII Complex in Type 3 Von Willebrand Disease
Status: COMPLETED
Conditions: Von Willebrand Disease
Interventions: BIOLOGICAL: Recombinant von Willebrand factor : recombinant FVIII (rVWF:rFVIII)|BIOLOGICAL: Marketed plasma-derived VWF/FVIII concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant Chemotherapy
Status: RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Epirubicin or Pirarubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Combined Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Catheter for Detection of Lipid Rich Plaque
Status: TERMINATED
Conditions: Coronary Artery Disease
Interventions: DEVICE: InfraReDx Lipiscan IVUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery
Status: COMPLETED
Conditions: Postoperative Cognitive Dysfunction
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Microcirculation in Colon Wall and Bowel Anastomosis by Laser Induced Fluorescence Video Angiography
Status: COMPLETED
Conditions: Colon Cancer|Benign Colon Diseases
Interventions: PROCEDURE: Elective colon resection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Culture is Care: Training Workshop for Care Workers (VerbaCurant)
Status: COMPLETED
Conditions: Empathy|Well-Being, Psychological
Interventions: OTHER: Training about storytelling and creative writing: 12 hours|OTHER: Training only about theoretical narrative medicine: 4 hours
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Acupoint Stimulation and Cranial Endovascular Treatment
Status: RECRUITING
Conditions: Cerebral Aneurysm
Interventions: DEVICE: transcutaneous electrical acupoint stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Immunotherapy for Recurrent Cervical Cancer Refractory to Platinum-based Chemotherapy
Status: COMPLETED
Conditions: Recurrent Cervical Carcinoma|Persistent Advanced Cervical Carcinoma|Chemotherapy|Anti-PD-1 Antibody|Immunotherapy
Interventions: DRUG: A combination of anti-PD-1 antibody camrelizumab and albumin-bound paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)
Status: UNKNOWN
Conditions: Down Syndrome|Obstructive Sleep Apnea|Child
Interventions: DIAGNOSTIC_TEST: Video clip assessment|DIAGNOSTIC_TEST: Polysomnography (sleep study)|OTHER: Educational webinar
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Konjac-Mannan Improves Glycemia and Other Risk Factors for CHD in T2DM
Status: COMPLETED
Conditions: Type2 Diabetes|Coronary Heart Disease
Interventions: DIETARY_SUPPLEMENT: konjac glucomannan|DIETARY_SUPPLEMENT: wheat bran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: PRETEXT I Hepatoblastoma|PRETEXT II Hepatoblastoma|PRETEXT III Hepatoblastoma|PRETEXT IV Hepatoblastoma
Interventions: DRUG: Cisplatin|DRUG: Dexrazoxane|DRUG: Doxorubicin Hydrochloride|DRUG: Fluorouracil|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Liver Transplantation|DRUG: Temsirolimus|PROCEDURE: Therapeutic Conventional Surgery|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Ability of Sublingual MV130 to Induce the Expression of Trained Immunity in Peripheral Blood Cells
Status: UNKNOWN
Conditions: Immune Response
Interventions: BIOLOGICAL: MV130|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: To Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese Participants
Status: COMPLETED
Conditions: Thrombosis
Interventions: DRUG: BMS-986177|OTHER: Matched Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars
Status: NOT_YET_RECRUITING
Conditions: Intracanal Medication|Bromelain|Calcium Hydroxide|Bacterial Load Reduction
Interventions: BIOLOGICAL: bromelain|DRUG: Calcium hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Elderly Demented Patients: Aromatherapy Complementary to Psychopharmacotherapy Psychological Disorders and BPSD Behavior
Status: COMPLETED
Conditions: BPSD (Behavioral and Psycological Symptoms of Dementia)
Interventions: OTHER: essential oils
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reduction of Auditory-Verbal Hallucinations in Schizophrenia Through Cortical Neuromodulation
Status: RECRUITING
Conditions: Treatment Resistant Schizophrenia
Interventions: DEVICE: Active Transcranial Magnetic Stimulation (TMS)|DEVICE: Sham Transcranial Magnetic Stimulation (TMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Assessment of Preheated Versus Conventional Bulk Fill Resin Composite
Status: UNKNOWN
Conditions: Clinical Significance of Thermo-Viscous Composite
Interventions: DEVICE: Viscalor Bulk (VOCO,Cuxhaven)|OTHER: Grandioso x-tra
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study to Evaluate the Feasibility and Potential Effectiveness of the Flexitouch System Head and Neck Treatment
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Head and Neck Cancer|Head and Neck Lymphedema
Interventions: DEVICE: Flexitouch head and neck lymphedema treatment system|OTHER: Standard home lymphedema care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Combined Therapy With Statin Plus Fenofibrate on Coronary Atherosclerotic Plaque Compared With Statin Alone
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Rosuvastatin and fenofibrate|DRUG: Rosuvastatin alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Dose-escalation Study to Investigate Safety and Pharmacokinetics/ Pharmacodynamics of WX-554 in Patients With Solid Tumours
Status: TERMINATED
Conditions: Advanced Solid Tumours
Interventions: DRUG: WX-554
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Efficacy and Safety of Pregabalin Against Frequent Muscle Cramp in Patients With Liver Cirrhosis
Status: COMPLETED
Conditions: Muscle Cramp|Liver Cirrhosis
Interventions: DRUG: Pregabalin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients
Status: UNKNOWN
Conditions: Essential Hypertension
Interventions: DRUG: Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xisomab 3G3 for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Receiving Chemotherapy
Status: TERMINATED
Conditions: Lymphoma|Malignant Solid Neoplasm|Plasma Cell Myeloma
Interventions: DRUG: Xisomab 3G3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Abemaciclib and Nivolumab for Subjects With Hepatocellular Carcinoma
Status: TERMINATED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Abemaciclib|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of DDI Between SHR1459 and Efavirenz With Healthy Subjects
Status: COMPLETED
Conditions: B-cell Tumors
Interventions: DRUG: SHR1459 tablet|DRUG: Efavirenz tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Young Gay/Bisexual Minority Men (IMPACT)
Status: NOT_YET_RECRUITING
Conditions: HIV
Interventions: BEHAVIORAL: IMPACT|BEHAVIORAL: eSOC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DNS-3379 vs. Placebo in Stroke Rehabilitation
Status: TERMINATED
Conditions: Ischemic Stroke
Interventions: DRUG: DNS-3379|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery
Status: COMPLETED
Conditions: Dexmedetomidine|Lidocaine 5% Patch|Arthroscopic Knee Surgery|Intra-articular
Interventions: DRUG: Lidocaine 5% patch with Dexmedetomidine Bupivacaine|DRUG: Dexmedetomidine Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study to Access Superficial Basal Cell Carcinoma in Adults
Status: COMPLETED
Conditions: Superficial Basal Cell Carcinoma
Interventions: DRUG: Tirbanibulin Ointment 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Adenocarcinoma of the Prostate
Interventions: RADIATION: HR-A|RADIATION: HR-B
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Gushen Antai Pill on Ongoing Pregnancy Rate in Women With Normal Ovarian Reserve Undergoing IVF-ET
Status: RECRUITING
Conditions: Infertility, Female
Interventions: DRUG: Gushen Antai Pill|DRUG: Placebo pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Hormone Therapy in Treating Women With Operable Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: goserelin acetate|DRUG: tamoxifen citrate|PROCEDURE: ablative endocrine surgery|PROCEDURE: oophorectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical and Radiographic Evaluation in Pulpotomy of Primary Molars Using Protooth Vs. MTA
Status: UNKNOWN
Conditions: Clinical Evaluation Including Pain and Swelling
Interventions: DRUG: Novel fast-setting calcium silicate cement (Protooth)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Delayed Cord Clamping During Resuscitation of Newborn Near Term and Term Infants
Status: RECRUITING
Conditions: Asphyxia Neonatorum|Resuscitation
Interventions: PROCEDURE: Intact cord (≥ 180 seconds) resuscitation|PROCEDURE: Early (≤ 60 seconds) cord clamping
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of DSP-2033 (Alvocidib) in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Alvocidib|DRUG: Cytarabine|DRUG: Mitoxantrone|DRUG: Cytarabine|DRUG: Daunorubicine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of BXCL701 and Pembrolizumab in Patients With mCRPC Either Small Cell Neuroendocrine Prostate Cancer or Adenocarcinoma Phenotype.
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Neuroendocrine Tumors|Small Cell Carcinoma
Interventions: DRUG: BXCL701 plus Pembrolizumab|DRUG: BXCL701 monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of a Cancerous Disease of the Peritoneum With Complete Cytoreductive Surgery and Intraperitoneal Chemohyperthermia
Status: TERMINATED
Conditions: Colon Tumors|Rectum Tumors|Appendix Tumors|Peritoneum Tumors|Endocrine Tumors
Interventions: DRUG: Oxaliplatin and irinotecan
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chimeric Antigen Receptor (CAR)-Modified T Cell Therapy in Treating Patients With Acute Lymphoblastic Leukemia
Status: UNKNOWN
Conditions: Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: CAR-T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Graft Thrombosis After Endovascular Aortic Repair - a Single Center Experience With the Cook Zenith Alpha Spiral-Z®
Status: COMPLETED
Conditions: Aorta Aneurysm
Interventions: PROCEDURE: Endovascular aortic repair with Zenith Alpha Spiral-Z®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Dexmedetomidine on Oxygenation and Lung Mechanics
Status: NOT_YET_RECRUITING
Conditions: Drug Use|Dexmedetomidine
Interventions: DRUG: GROUP Dexmedetomidine|DRUG: GROUP B|DRUG: GROUP C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TMS for Adults With Autism and Depression
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Depression|Depressive Disorder|Major Depressive Disorder
Interventions: DEVICE: NeuroStar® TMS device (Neuronetics, Atlanta, GA)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Standard Versus Mnemonic Counseling for Fecal Incontinence
Status: COMPLETED
Conditions: Fecal Incontinence|Counselling|Patient Satisfaction
Interventions: OTHER: Type of Counselling (Mnemonic)|OTHER: Standard
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Niraparib + Nivolumab|DRUG: Niraparib + Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Of Effect Of PF-03882845 On Simvastatin Pharmacokinetics
Status: COMPLETED
Conditions: Human Volunteers
Interventions: DRUG: Simvastatin/PF-03882845
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE