pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Multi-center RCT Study on the Efficacy and Mechanism of Multi-channel tDCS in Rehabilitation of Cognitive Function After Stroke
Status: UNKNOWN
Conditions: Cognitive Dysfunction
Interventions: DEVICE: multi-channel tDCS|DEVICE: single-channel tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Ingenol Mebutate Gel 0.015% Compared to Diclofenac Sodium Gel 3% in Subjects With Actinic Keratoses on the Face or Scalp
Status: COMPLETED
Conditions: Actinic Keratosis (AK)
Interventions: DRUG: Ingenol Mebutate Gel, 0.015%|DRUG: Diclofenac sodium gel 3%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness and Safety of Duloxetine in Women Experiencing Urinary Leakage Due to Physical Stress and Urge.
Status: COMPLETED
Conditions: Urinary Incontinence, Stress
Interventions: DRUG: duloxetine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention
Status: UNKNOWN
Conditions: Antiplatelet Therapy|Coronary Artery Disease|Percutaneous Coronary Intervention
Interventions: DRUG: Ticagrelor 90mg|DRUG: Ticagrelor 90mg/60mg|DRUG: Clopidogrel 75mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Effect of Multiple Doses of AZD7325, CYP Study
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: AZD7325|DRUG: Midazolam|DRUG: Caffeine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effectiveness and Cost-effectiveness of vCST and Online Dementia Carer Support
Status: RECRUITING
Conditions: Dementia
Interventions: BEHAVIORAL: f2f CST|BEHAVIORAL: f2f carer support|BEHAVIORAL: vCST|BEHAVIORAL: online carer support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: To Assess the Risk of Acute Pancreatitis in Patients With Type 2 Diabetes Mellitus Treated With Empagliflozin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: empagliflozin|DRUG: Oral non-incretin/non-sodium glucose co-transporter-2 inhibitors (SGLT2)-containing hypoglycaemic agents
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mesenteric Vessel Sealing by Three Instruments
Status: COMPLETED
Conditions: Surgery
Interventions: DEVICE: LOTUS|DEVICE: Ethicon Harmonic Scalpel|DEVICE: LigaSure bipolar vessel sealing device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of HIV-1, HCV and HBV Blood Screening Tests With Human Blood Donor Specimens
Status: COMPLETED
Conditions: Screening for the Presence of HIV-1, RNA and HBV DNA in Blood Donations
Interventions: DEVICE: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Transplantation of Cultivated Limbal Epithelium on Amniotic Membrane for Limbal Stem Cell Deficiency
Status: SUSPENDED
Conditions: Ocular Surface Disease
Interventions: PROCEDURE: Transplantation of cultivated limbal epithelium
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Defecation Posture on Ease of Bowel Movements in Patients With a Rectocele
Status: NOT_YET_RECRUITING
Conditions: Pelvic Organ Prolapse|Rectocele|Bowel Dysfunction
Interventions: DEVICE: Defecation Posture Modification Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Analysis of Robot-Assisted Surgery
Status: UNKNOWN
Conditions: Esophageal Cancer|Gastric Cancer|Pancreatic Cancer|Rectal Cancer|Bladder Cancer|Prostate Cancer|Renal Cancer|Uterus Cancer|Head and Neck Cancer|Lung Cancer
Interventions: PROCEDURE: Robot-assisted surgery|PROCEDURE: Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Exercises on Physiological Changes and Clinical Symptoms in Allergic Rhinitis Patients
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: Aerobic exercise with Vit. C|OTHER: Aerobic exercise|OTHER: No exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Efficacy of Vilaprisan in Patients With Uterine Fibroids
Status: COMPLETED
Conditions: Leiomyoma
Interventions: DRUG: Vilaprisan (BAY1002670)|DRUG: Vilaprisan (BAY1002670|DRUG: Vilaprisan (BAY1002670|DRUG: Vilaprisan (BAY1002670)|DRUG: Ulipristal|DRUG: Ulipristal|DRUG: Ulipristal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma
Status: UNKNOWN
Conditions: Advanced Glaucoma|Refractory Glaucoma
Interventions: PROCEDURE: Micropulse Transscleral Cyclophotocoagulation|PROCEDURE: Conventional Transscleral Cyclophotocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quantitative Ablation of Pulmonary Vein Vestibule in Paroxysmal Atrial Fibrillation.
Status: UNKNOWN
Conditions: Atrial Fibrillation|Arrythmia
Interventions: PROCEDURE: High AI in paroxysmal atrial fibrillation|PROCEDURE: Middle AI in paroxysmal atrial fibrillation|PROCEDURE: Low AI in paroxysmal atrial fibrillation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MIND Foods and Aerobic Training in Black Adults With HTN
Status: RECRUITING
Conditions: Cognitive Decline|Hypertension|Diet|Aerobic Exercise
Interventions: BEHAVIORAL: Enhanced Usual Care (EUC)|BEHAVIORAL: Food Delivery and Cooking PLUS Aerobic Training (FoRKS+)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Refractory Out-Of-Hospital Cardiac Arrest Treated With Mechanical CPR, Hypothermia, ECMO and Early Reperfusion
Status: UNKNOWN
Conditions: Cardiac Arrest
Interventions: DEVICE: Automated CPR|DEVICE: ECMO|PROCEDURE: Coronary angiography|PROCEDURE: Therapeutic Hypothermia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Recurrence of Atrial Fibrillation Post Cryoballon Ablation During the 90-day Blanking Period-with and Without Anti-arrhythmic Drug Therapy
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: OTHER: No AAD post Ablation.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dorsal Genital Nerve Stimulation for Bladder Management After SCI
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Cord Injuries|Neurogenic Bladder|Neurogenic Detrusor Overactivity|Neurogenic Bladder Dysfunction
Interventions: DEVICE: Neuromodulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Polycan in Combination With Glucosamine for Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DIETARY_SUPPLEMENT: Glucosamine 1500 mg|DIETARY_SUPPLEMENT: Polycan 50mg + Glucosamine 750 mg|DIETARY_SUPPLEMENT: Polycan 50mg + Glucosamine 1500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Application of Wide Pulse High Frequency Neuromuscular Electrical Stimulation in Disorders Associated With Motoneuron Hyperexcitability
Status: RECRUITING
Conditions: Stroke|Cramp|Restless Legs Syndrome|Healthy Volunteers
Interventions: OTHER: wide pulse high frequency neuromuscular electrical stimulation training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of DCB-WH1 in Healing of Chronic Diabetic Foot Ulcers
Status: COMPLETED
Conditions: Chronic Diabetic Foot Ulcer
Interventions: DRUG: DCB-WH1 ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Melflufen and Dexamethasone in Relapsed and/or Relapsed-Refractory Multiple Myeloma Patients
Status: TERMINATED
Conditions: Relapsed and/or Relapsed-refractory Multiple Myeloma
Interventions: DRUG: Melflufen|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Aquamid as Compared to Restylane for the Aesthetic Treatment of Nasolabial Folds
Status: COMPLETED
Conditions: Facial Wrinkles
Interventions: DEVICE: Aquamid|DEVICE: Restylane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cigarette Smoking in Smokers With and Without Schizophrenia
Status: RECRUITING
Conditions: Tobacco Dependence|Schizophrenia
Interventions: COMBINATION_PRODUCT: Sampling Research Cigarettes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Colchicine to Treat and Prevent Recurrent Pericarditis (First Episode)
Status: COMPLETED
Conditions: Pericarditis|Recurrence
Interventions: DRUG: Colchicine (for 6 months)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Sublingual Sufentanil Tablet System (SSTS) Versus Intravenous Patient Controlled Analgesia After Back Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DEVICE: Sublingual sufentanil tablet system|DRUG: Patient-controlled intravenous analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Levetiracetam Treatment of Children With Subclinical Sleep-Activated Epileptiform Activity (SSEA)
Status: UNKNOWN
Conditions: Subclinical Sleep-Activated Epileptiform Activity|CSWS
Interventions: DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: T-ACE Oil by TAE/TACE in Patients With Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: T-ACE Oil|DRUG: Lipiodol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Decision-Framing in Psoriasis
Status: COMPLETED
Conditions: Psoriasis Vulgaris|Psoriatic Arthritis|Psoriasis
Interventions: BEHAVIORAL: Decision-Framed Survey
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Comparison of Two Different Drug Regimens for Medical Treatment of Early Pregnancy Loss
Status: UNKNOWN
Conditions: Abortion, Missed
Interventions: DRUG: Mifepristone, Oral, 200 Mg|DRUG: Misoprostol Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of Radiosensitization Using Bortezomib in Relapsed Non-Hodgkin's Lymphoma Patients Receiving Radioimmunotherapy
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma
Interventions: DRUG: bortezomib, tositumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya
Status: NOT_YET_RECRUITING
Conditions: Father-Child Relations|Depression|Alcohol Use, Unspecified
Interventions: BEHAVIORAL: LEAD (Learn, Engage, Act, Dedicate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fuzzy Logic Automated Insulin Regulation
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DEVICE: MedtronicMinimed 670G 3.0 hybrid closed loop system|DEVICE: Medtronic Minimed 670G 4.0 AHCL with Guardian Sensor (3) continuous glucose monitoring sensor.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Biocriminology and the Adjudication of Criminal Responsibility: Is There a Consensus Among Scientists' Verdicts?
Status: COMPLETED
Conditions: Criminalism
Interventions: BEHAVIORAL: Biocriminological Evidence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Safety and Efficacy of ONO-7746 in Adult Cancer Patients With Chemotherapy Induced Thrombocytopenia
Status: TERMINATED
Conditions: Chemotherapy-Induced Thrombocytopenia
Interventions: DRUG: ONO-7746
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regorafenib Versus Placebo to Treat Cholangiocarcinoma
Status: UNKNOWN
Conditions: Cholangiocarcinoma
Interventions: DRUG: Regorafenib/active|DRUG: Regorafenib/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Explore Pharmacokinetic Interaction Between Rilpivirine and Metformin in Healthy Participants
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: Metformin|DRUG: Rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Maxillary Expansion Treatment of Pediatric OSA
Status: COMPLETED
Conditions: Obstructive Sleep Apnea
Interventions: PROCEDURE: Maxillary expansion|PROCEDURE: Adenotonsillectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Hyperthermic Intraperitoneal Chemotherapy for Advanced Gastric Cancer With Peritoneal Metastatis
Status: UNKNOWN
Conditions: Stage IV Gastric Cancer With Metastasis|Hyperthermic Intraperitoneal Chemotherapy|Exploratory Behavior
Interventions: DRUG: Hyperthermic Intraperitoneal Chemotherapy|DRUG: Without Hyperthermic Intraperitoneal Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HYSTERIA Evaluation of Clinical HYpnosis After Surgical Resection for Crohn Disease on Post-operative Analgesia
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Anesthesia
Interventions: PROCEDURE: Hypnosis|PROCEDURE: usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Thymosin-alpha 1 for Adjuvant Treatment After Radical Resection of High-risk Stage II and III Colorectal Cancer
Status: RECRUITING
Conditions: Stage II Colorectal Cancer|Stage III Colorectal Cancer
Interventions: DRUG: Thymosin Alpha1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Local Anesthetic Infusion Following Hernia Repair
Status: COMPLETED
Conditions: Ventral Hernia
Interventions: PROCEDURE: Pain management following hernia repair|PROCEDURE: Placebo for pain management following hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After Rehabilitation
Status: RECRUITING
Conditions: Hepatic Encephalopathy
Interventions: BEHAVIORAL: Rehabilitation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Immunotherapy to Treat Advanced Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Ipilimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness of a Modified Community Model in Improving Child Health Outcomes in Mashonaland East, Zimbabwe
Status: COMPLETED
Conditions: Pneumonia|Diarrhea|Malnutrition|Fever
Interventions: BEHAVIORAL: prevention and management of childhood illnesses at community level|BEHAVIORAL: conventional community interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Triptorelin for Ovary Protection in Childhood Onset Lupus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Triptorelin pamoate|DRUG: Triptorelin Pamoate|DRUG: Triptorelin Pamoate|DRUG: Triptorelin Pamoate|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Intramuscular Electrical Stimulation for the Treatment of Trigger Points in Patients With Migraine
Status: RECRUITING
Conditions: Chronic Migraine
Interventions: PROCEDURE: Dry Needling and intramuscular electrical stimulation to trigger points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers
Status: RECRUITING
Conditions: Gastric Cancer|Gastric Neoplasms|Gastric Adenocarcinoma
Interventions: DEVICE: Cellvizio (Registered trademark)Real-Time In Vivo Cellular Imaging Platform with Confocal Miniprobes|DEVICE: Olympus GIF 190 endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase ll Study of Imatinib Mesylate for the Neoadjuvant Treatment of Patients With Gastrointestinal Stromal Tumors (GIST)
Status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Spinal Manipulation Therapy Impact Lumbar Proprioception
Status: COMPLETED
Conditions: Manipulation, Psychologic|Proprioception|Vibration; Exposure
Interventions: PROCEDURE: spinal manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol
Status: COMPLETED
Conditions: Alcohol Dependence|Alcohol Interaction
Interventions: DRUG: PT150|OTHER: Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: OTHER: Pharmacist based QI program|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Tamoxifen Compared With Clomiphene Citrate for Women Who Had Thin Endometrium Women Under Clomiphene in a Previous Cycle
Status: UNKNOWN
Conditions: Infertility
Interventions: DRUG: tamoxifen|DRUG: clomiphene citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Arthroscopic Assisted Lateral Soft Tissue Release for Hallux Valgus
Status: COMPLETED
Conditions: Hallux Valgus|Hallux Valgus and Bunion
Interventions: PROCEDURE: Arthroscopic lateral soft tissue release
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Quality of Life, Efficacy, and Tolerance of Duac® Gel Compared to Differin® Gel in the Treatment of Acne
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: DRUG: Duac Gel|DRUG: Differin gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
Status: ACTIVE_NOT_RECRUITING
Conditions: Colorectal Cancer
Interventions: BEHAVIORAL: Trial Mailed FIT Intervention - Age Group 50-75|BEHAVIORAL: Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49|BEHAVIORAL: Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy
Status: COMPLETED
Conditions: Dental Caries|Oral Cavity Cancer|Oral Complications of Chemotherapy and Head/Neck Radiation
Interventions: OTHER: Tray|OTHER: Brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of 308-nm Excimer Lamp Combined With Tacrolimus vs Tacrolimus as Monotherapy in Treating Vitiligo on Children
Status: COMPLETED
Conditions: Vitiligo|Pediatric ALL|Dermatologic Disease|Autoimmune Diseases
Interventions: DEVICE: exciplex|DRUG: Tacrolimus ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Impact of Lesions of the Motor and Proprioceptive Brain and Pan-medullary Pathways on Their Clinically and Electrophysiologically Assessed Function in Multiple Sclerosis
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis, Relapsing-Remitting
Interventions: RADIATION: MRI|OTHER: Electrophysiology
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Trial of Gemcitabine, Infusional 5-Fluorouracil and Cisplatin for Advanced Pancreatic and Biliary Cancers
Status: COMPLETED
Conditions: Pancreatic Cancer|Biliary Cancer
Interventions: DRUG: Gemcitabine|DRUG: 5-FU|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open-label Study of Subcutaneous Secukinumab to Evaluate Efficacy and Safety in Patients With Plaque Psoriasis Who Had Inadequate Response to Cyclosporine A
Status: COMPLETED
Conditions: Plaque Psoriasis
Interventions: DRUG: Secukinumab (AIN457)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metabolic Actions of Omega-3 Fatty Acids
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: EPA (marine fatty acids)|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Management Of Patellar Fractures By Craniofacial Mesh Plate Osteosynthesis Augmented by Screws
Status: RECRUITING
Conditions: Patella Fracture
Interventions: PROCEDURE: fixation of patella fractures by craniofacial mesh plate osteosynthesis augmented by screws
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Study Aims to Improve the Accuracy of Detecting Spina Bifida During Early Ultrasound Scans. To Achieve This, an AI Model Has Been Developed to Provide Feedback About the Presence of Spina Bifida. A RCT Has Been Designed to Compare the Effectiveness of AI Feedback With no AI Feedback.
Status: NOT_YET_RECRUITING
Conditions: Spina Bifida
Interventions: OTHER: Evaluation of XAI-assisted spina bifida diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Multiple Ascending Dose to Study the Safety, Tolerability, PK and PD Effects of AEF0117
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: AEF0117 oral capsule|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase II Study in the Treatment of Patients With Advanced Mucinous Melanoma
Status: UNKNOWN
Conditions: Advanced Mucosal Melanoma
Interventions: BIOLOGICAL: JS001(Toripalimab Injection)|DRUG: Axitinib 1 MG [Inlyta]|OTHER: JS001 and Axitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Repetitive Peripheral Magnetic Stimulation on Upper Extremity Spasticity After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: therapeutic repetitive peripheral magnetic stimulation|DEVICE: sham repetitive peripheral magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: New AntiBiotic Treatment Options for Uncomplicated Anogenital GOnorrhoea
Status: COMPLETED
Conditions: Gonorrhea
Interventions: DRUG: Ertapenem 1000 MG|DRUG: Fosfomycin Oral Suspension|DRUG: Gentamicin Sulfate, Injectable|DRUG: Ceftriaxone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dry Needling Versus Graston Technique in Active Myofascial Trigger Points on Upper Trapezius
Status: COMPLETED
Conditions: Trigger Points
Interventions: OTHER: Dry Needling Group|OTHER: Graston Technique Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Plasma Insulin Levels on the Accuracy of Continuous Subcutaneous Glucose Monitoring
Status: COMPLETED
Conditions: Type 1 Diabetes|Continuous Glucose Monitoring|Hypoglycemia
Interventions: OTHER: High insulin eu-hypoglycemic clamp|OTHER: Low insulin eu-hypoglycemic clamp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparative Effectiveness of a Kinect-based Unilateral Arm Training System vs Constraint-Induced Therapy for Children With Cerebral Palsy
Status: RECRUITING
Conditions: Cerebral Palsy
Interventions: OTHER: Constraint-induced therapy|OTHER: kinect-based constraint-induced therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of a Novel Paclitaxel-coated Balloon With Citrate Excipient for Restenosis in -Limus Analogue DES
Status: COMPLETED
Conditions: Coronary Restenosis
Interventions: DEVICE: PCB
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lubiprostone for Functional Constipation in the Under 18 Years Patients
Status: COMPLETED
Conditions: Clinical Efficacy|Treatment Efficacy|Drug Side Effect
Interventions: DRUG: Lubiprostone Pill|DRUG: Lactulose Oral Liquid Product|DRUG: Bisacodyl 5 MG|DRUG: Sodium Picosulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Deep Brain Stimulation (DBS) For Parkinson's Disease: Caudal Zona Incerta Versus Subthalamic Nucleus
Status: UNKNOWN
Conditions: Parkinson's Disease
Interventions: PROCEDURE: deep brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Durvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractant Exposure
Status: COMPLETED
Conditions: Breast Cancer|Estrogen Receptor Positive Tumor|Menopause|Hormone Antagonist
Interventions: DRUG: Immune-attractant|DRUG: Durvalumab|PROCEDURE: Biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Use of Shengmai San to Prevent Anthracycline Sequential Trastuzumab Therapy Related Cardiac Toxicity
Status: RECRUITING
Conditions: Cardiotoxicity Induced by Drug Therapy for Breast Cancer
Interventions: DRUG: Shengmai San (ingredients include ginseng, Ophiopogon japonicus, and Schisandra chinensis)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Oxaliplatin With Gemcitabine in Patients With Carcinoma of the Urothelial Tract
Status: TERMINATED
Conditions: Carcinoma, Transitional Cell
Interventions: DRUG: gemcitabine, oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sleep Architecture & Intrinsic Oscillatory and Network Connectivity in Cognition and Executive Dysfunction in TLE
Status: NOT_YET_RECRUITING
Conditions: Temporal Lobe Epilepsy
Interventions: OTHER: Acoustic Stimulation (AS)|OTHER: SHAM Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: N-Acetyl Cystein and Contrast Nephropathy
Status: UNKNOWN
Conditions: Chronic Kidney Disease Stage 2|Radiographic Contrast Agent Nephropathy
Interventions: DRUG: Oral N-Acetyl Cystein|DRUG: IV N-Acetyl Cystein|DRUG: Placebo group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus
Status: UNKNOWN
Conditions: Infective Endocarditis
Interventions: DRUG: Amoxicillin|PROCEDURE: Conventional IV treatment of streptococci/enterococci IE following European guidelines 2015 including amoxicillin, gentamicin, amicillin, vancomycin, penicillin G, ceftriaxone, netilmicin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study on Edoxaban for the Resolution of Left Atrial Thrombosis in Patients With Non-valvular Atrial Fibrillation
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Edoxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers
Status: COMPLETED
Conditions: Pharmacokinetics|Safety|Tolerability
Interventions: DRUG: 5-methoxy-N,N-dimethyltryptamine succinate salt|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Sunitinib Malate, Paclitaxel, Doxorubicin Hydrochloride, and Cyclophosphamide Before Surgery in Treating Patients With Stage IIB-IIIC Breast Cancer
Status: COMPLETED
Conditions: Inflammatory Breast Cancer|Male Breast Cancer|Stage II Breast Cancer|Stage IIIA Breast Cancer|Stage IIIB Breast Cancer|Stage IIIC Breast Cancer
Interventions: DRUG: sunitinib malate|DRUG: paclitaxel|DRUG: doxorubicin hydrochloride|DRUG: cyclophosphamide|BIOLOGICAL: filgrastim|PROCEDURE: therapeutic conventional surgery|OTHER: laboratory biomarker analysis|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Herbal Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Hypericum perforatum|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Utility and Acceptability of a Molecular Test in the Management of Sexually Transmitted Diseases in Uganda
Status: RECRUITING
Conditions: Sexually Transmitted Diseases
Interventions: DIAGNOSTIC_TEST: nuclear acid amplification tests|OTHER: Clinical Syndromic Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Baduanjin Exercise Prevents Post-Myocardial Infarction Left Ventricular Remodeling (BE-PREMIER Trial)
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: OTHER: Baduanjin exercise|OTHER: aerobic exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of SDMB (2,2 Dimethylbutyrate, Sodium Salt) in Beta Thalassemia Intermedia in Thailand
Status: COMPLETED
Conditions: Beta Thalassemia Intermedia
Interventions: DRUG: sodium 2,2 dimethylbutyrate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stress, Personality, Attachment and Coping During the Covid Crisis.
Status: COMPLETED
Conditions: Psychiatric Disorder|Aging
Interventions: OTHER: PTSD Check List (PCL) scale|OTHER: Brief COPE scale|OTHER: GAD-7 (Generalized Anxiety Disorder) scale (during containment)|OTHER: Analog scale|OTHER: GAD-7 (Generalized Anxiety Disorder) scale (post containment)|OTHER: Big Five Inventory (BFI) scale|OTHER: Relationship Scales Questionnaire (RSQ)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lactoferrin Treatment in HIV Patients
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Recombinant Lactoferrin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anticipating Decline and Providing Therapy
Status: RECRUITING
Conditions: Cognitive Impairment|Dementia|Post ICU Syndrome|Critical Illness|Cognitive Impairment, Mild
Interventions: BEHAVIORAL: Usual Care post-Intensive Care Unit (ICU)|BEHAVIORAL: Anticipating Decline and Providing Therapy (ADAPT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Prognostic Value of Preoperative Quadriceps and Respiratory Muscle Thickness by Ultrasound Measurement in Cardiac and Thoracic Surgery Patients
Status: RECRUITING
Conditions: Cardiac Surgery With Extracorporeal Circulation|Thoracic Surgery
Interventions: OTHER: Ultrasound of the abdominal wall muscles|OTHER: Ultrasound quadricipital|OTHER: Ultrasound of the diaphragm|OTHER: Ultrasound of the inter-costal muscles|OTHER: Ultrasound of the inter-costal muscles
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of a Fish Oil Containing Lipid Emulsion
Status: COMPLETED
Conditions: Parenteral Nutrition
Interventions: DRUG: fish oil containing lipid emulsion|DRUG: MCT/LCT containing lipid emulsion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Comparator: ER niacin (+) laropiprant|DRUG: Comparator: ER niacin|DRUG: Comparator: laropiprant|DRUG: Comparator: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of HBV Therapeutic Vaccines GS-2829 and GS-6779 in Healthy Participants and Participants With Chronic Hepatitis B
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Hepatitis B
Interventions: BIOLOGICAL: GS-2829|BIOLOGICAL: GS-6779|BIOLOGICAL: Placebo for GS-2829|BIOLOGICAL: Placebo for GS-6779
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
Status: ACTIVE_NOT_RECRUITING
Conditions: Osteoarthritis, Knee|Osteo Arthritis Knee|Knee Osteoarthritis
Interventions: GENETIC: GNSC-001|DRUG: transient immune-modulation|DRUG: transient immune-modulation|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Micro Vibratory Stimulation Technique to Control the Pain of Digit Block Anesthesia
Status: COMPLETED
Conditions: Pain, Analgesia
Interventions: DEVICE: Microvibratory Stimulator|DEVICE: Microvibratory Stimulator'
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy and Ammonium Tetrathiomolybdate in Treating Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
Status: WITHDRAWN
Conditions: Lung Cancer
Interventions: DRUG: ammonium tetrathiomolybdate|OTHER: immunoenzyme technique|OTHER: laboratory biomarker analysis|RADIATION: Tc 99m sestamibi|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Group-Mediated Cognitive Behavioral Resistance Exercise Intervention in Head and Neck Cancer Patients Undergoing Chemoradiation Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: OTHER: Counseling|BEHAVIORAL: Dietary Counseling and Surveillance|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration|OTHER: Resistance Training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assessment of 5-Aminosalicylic Acid Prescription Patterns and Treatment Outcomes in Patients With Ulcerative Colitis in Korea
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: OTHER: PENTASA (mesalamine/ 5-Aminosalicylic acid (5-ASA)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Anlotinib Hydrochloride Combined With Liposomal Doxorubicin in the Treatment of Locally Advanced or Metastatic Soft Tissue Sarcoma
Status: UNKNOWN
Conditions: Sarcoma
Interventions: DRUG: Anlotinib+ Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MK0916 in Patients With Type 2 Diabetes and Metabolic Syndrome (0916-005)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Metabolic Syndrome
Interventions: DRUG: MK0916
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Obinutuzumab, High Dose Methylprednisolone (HDMP), and Lenalidomide for the Treatment of Patients With Richter's Syndrome
Status: COMPLETED
Conditions: Richter's Syndrome|CLL
Interventions: DRUG: Obinutuzumab|DRUG: lenalidomide|DRUG: HDMP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of AJOVY (Fremanezumab-vfrm) on Interictal Migraine Related Burden
Status: COMPLETED
Conditions: Migraine
Interventions: DRUG: Fremanezumab-Vfrm 225 MG/1.5 ML Subcutaneous Solution [AJOVY]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Previously Untreated HIV-Associated Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|BIOLOGICAL: rituximab|DRUG: CHOP regimen|DRUG: cyclophosphamide|DRUG: doxorubicin hydrochloride|DRUG: prednisone|DRUG: vincristine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Performance of Ellume·Lab Group A Strep Test Versus Culture for the Rapid Detection of Group A Streptococcus in Participants With Acute Pharyngitis
Status: WITHDRAWN
Conditions: Group A Streptococcal Infection
Interventions: DIAGNOSTIC_TEST: ellume·lab Group A Streptococcus Test|DIAGNOSTIC_TEST: Bacterial Culture|DIAGNOSTIC_TEST: Polymerase Chain Reaction (PCR)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: First in Human Evaluation of Safety, Pharmacokinetics, and Clinical Activity of a Monoclonal Antibody Targeting Netrin 1 in Patients With Advanced/Metastatic Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumor|Endometrial Carcinoma|Hormone Receptor Positive
Interventions: DRUG: NP137 DL and RP2D
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of NanoPac Intratumoral Injection in Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer, Nonsmall Cell|Lung Cancer|Lung Cancer, Small Cell|Neoplasm of Lung
Interventions: DRUG: NanoPac (sterile nanoparticulate paclitaxel) Powder for Suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Botulinum Neurotoxin A With Rehabilitation Versus Botulinum Neurotoxin A Alone in Treatment of Post-stroke Spasticity
Status: COMPLETED
Conditions: Upper Limb Spasticity
Interventions: DRUG: Botulinum toxin type A, BoNT-A|OTHER: Rehabilitation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Eniluracil and Surgery in Treating Patients With Primary or Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: eniluracil|PROCEDURE: conventional colon surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cancer Immune Therapy for the Treatment of Refractory Solid Tumours of Childhood
Status: COMPLETED
Conditions: Childhood Solid Tumor
Interventions: BIOLOGICAL: AV0113 DC-CIT|OTHER: Data evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EARLY ACS: Early Glycoprotein IIb/IIIa Inhibition in Patients With Non-ST-segment Elevation Acute Coronary Syndrome (Study P03684AM2)(COMPLETED)
Status: COMPLETED
Conditions: Myocardial Ischemia|Acute Coronary Syndrome
Interventions: DRUG: Eptifibatide (Integrilin)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Serum Vasohibin, Cardiotrophin, Endocan & Perinatal Outcomes
Status: RECRUITING
Conditions: Preeclampsia|Gestational Hypertension|Gestational Diabetes|Preterm Birth|Fetal Growth Retardation
Interventions: DIAGNOSTIC_TEST: first trimester serum diagnostic test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p