pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fecal Transplantation in Ulcerative Colitis
Status: UNKNOWN
Conditions: Ulcerative Colitis
Interventions: OTHER: Fecal microbiota transplantation (FMT)|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Combination Treatment With DW1501-R1+DW1501-R2 Versus DW1501-R1 or DW1501-R2+DW1501-R3 in Patients With Hypertension and Dyslipidemia
Status: COMPLETED
Conditions: Hypertension|Dyslipidemia
Interventions: DRUG: Telmisartan + Amlodipine + Rosuvastatin|DRUG: Telmisartan + Amlodipine|DRUG: Telmisartan + Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Thoracic Mulligan Mobilization on Sub-acromial Impingement Syndrome
Status: COMPLETED
Conditions: Shoulder Impingement Syndrome
Interventions: OTHER: mulligan thoracic Sustained Natural Apophyseal Glides|OTHER: traditional treatments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Nivolumab and BMS986205 in Treating Patients With Stage II-IV Squamous Cell Cancer of the Head and Neck
Status: TERMINATED
Conditions: Lip|Oral Cavity Squamous Cell Carcinoma|Pharynx|Larynx|Squamous Cell Carcinoma
Interventions: BIOLOGICAL: Nivolumab|BIOLOGICAL: IDO1 Inhibitor BMS-986205|PROCEDURE: Therapeutic Conventional Surgery|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evolution of Intestinal Microbiota in Patients With Juvenile Spondylarthropathy According to Typology of Treatment
Status: RECRUITING
Conditions: Spondylarthropathies
Interventions: OTHER: Stool collection at the patient's home.|DIAGNOSTIC_TEST: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Dose-Response Biomarker Study of Brexpiprazole Treatment in PTSD
Status: TERMINATED
Conditions: Post Traumatic Stress Disorder
Interventions: DRUG: Brexpiprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Graft Perfusion and Oxygenation for Improved Outcome in Esophageal Cancer Surgery
Status: RECRUITING
Conditions: Anastomotic Leak|Esophageal Cancer
Interventions: DIAGNOSTIC_TEST: Indocyanine green angiography|DIAGNOSTIC_TEST: Hemodynamic evaluation|DIAGNOSTIC_TEST: Biological and pathological markers of ischemia
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
Status: RECRUITING
Conditions: Major Depressive Disorder
Interventions: DRUG: Ketamine|DRUG: Esketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short-course Versus Long-course Pre-operative Chemotherapy With mFOLFIRINOX or PAXG (CASSANDRA TRIAL)
Status: UNKNOWN
Conditions: Pancreas Ductal Adenocarcinoma
Interventions: DRUG: PAXG|DRUG: mFOLFIRINOX|DRUG: short-course chemotherapy|DRUG: long-course chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reconstruction Plate Compared With Flexible Intramedullary Nailing for Midshaft Clavicular Fractures
Status: COMPLETED
Conditions: Clavicle Fracture
Interventions: PROCEDURE: Plate fixation|PROCEDURE: ESIN
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratic Phenotypic Optimisation Platform (QPOP) Utilisation to Enhance Selection of Patient Therapy Through Patient Derived Organoids in Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DEVICE: QPOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-Ranging Study of A006 DPI, in Adult Asthma Patients
Status: COMPLETED
Conditions: Asthma|Bronchospasm
Interventions: DRUG: albuterol inhalation powder|DRUG: albuterol inhalation powder|DRUG: albuterol inhalation powder|DRUG: albuterol inhalation powder|DRUG: Placebo|DRUG: albuterol inhalation aerosol|DRUG: albuterol inhalation aerosol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Postprandial Lipid Tracer and Exercise in Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injuries
Interventions: BEHAVIORAL: Seated control (CON)|BEHAVIORAL: Arm cycle exercise (ACE)|BEHAVIORAL: Liquid meal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Autologous Adipose-derived Stem Cells (ASCs) for the Treatment of Perianal Fistula in Crohn Disease: A Pilot Study
Status: UNKNOWN
Conditions: Perianal Fistula|Crohn Disease
Interventions: PROCEDURE: ASCs injection|DEVICE: ASCs injection|DEVICE: Closure of fistula tract.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Stationary Breast Tomosynthesis and 2-D Digital Mammography in Patients With Breast Augmentation
Status: WITHDRAWN
Conditions: Mammogram Scheduled
Interventions: DEVICE: Stationary Breast Tomosynthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Attention Bias Modification Treatment for Children With Social Anxiety
Status: COMPLETED
Conditions: Social Phobia
Interventions: BEHAVIORAL: Attention Bias Modification Treatment (ABMT)|BEHAVIORAL: Attention Control Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: BATTLE Program: Tarceva and Targretin in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Bexarotene|DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Attention Orienting to Social Threat to Reduce Social Anxiety in Youth
Status: RECRUITING
Conditions: Social Anxiety Disorder of Childhood
Interventions: BEHAVIORAL: Attention Bias Modification Treatment|BEHAVIORAL: Neutral Control Task
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: RENACTIF: Reduction of the Thrombotic Phenotype in Renal Insufficiency With N-AcetylCysteine
Status: COMPLETED
Conditions: Chronic Kidney Diseases
Interventions: DRUG: N-acetylcysteine (NAC)|DRUG: Placebo|BIOLOGICAL: Blood sample|BIOLOGICAL: Blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Validation of a Scale to Evaluate the Perception of Oral Health in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Questionnaires completed at D0|OTHER: Questionnaires completed at D15 (test-retest for 30 patients)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: A Randomized, Placebo-Controlled, Double-Blinded Phase I Safety and Immunogenicity Trial of Recombinant Envelope Protein, HIV-1 SF-2 rgp120 (BIOCINE), Combined With MF59 in HIV-1 Uninfected Adult Volunteers
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: MF59|BIOLOGICAL: rgp120/HIV-1 SF-2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: New Adjuvant Treatment of Locally Advanced Resectable Gastric Cancer With Carelizumab and XELOX
Status: RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: Carrelizumab combined with XELOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Temporal Immunologic Changes With Hypofractionated Radiation-Induced DNA Damage in Breast Cancer
Status: RECRUITING
Conditions: Breast Carcinoma|Invasive Breast Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|RADIATION: Radiation Therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of the 90% Effective Dose of a Sufentanil Bolus in Analgesia During Lateral Decubitus of Mechanically Ventilated Patients
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Sufentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Cigarette Holders, Plastic Menthol Cigarettes, and Cognitive Behavioral Therapy for Smoking Reduction Among Schizophrenia Inpatients: A Comparative Study
Status: COMPLETED
Conditions: Schizophrenia|Heavy Smoking
Interventions: BEHAVIORAL: Behavior therapy, cigarette holders, Flowers Menthol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)
Status: RECRUITING
Conditions: Small-cell Lung Cancer|Extensive-stage Small-cell Lung Cancer|Lung Cancer
Interventions: RADIATION: Ablative Radiation|DRUG: Durvalumab|DRUG: Etoposide|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Extension Study Assessing the Efficacy and Safety of Brolucizumab in a Treat-to-Control Regimen in Patients With Neovascular Age-related Macular Degeneration Who Have Completed the CRTH258A2303 (TALON) Study
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: DRUG: brolucizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Human Allogeneic Bone-marrow-derived Mesenchymal Stromal Cell Product (StromaForte) in Patients With Aging Frailty
Status: NOT_YET_RECRUITING
Conditions: Frailty
Interventions: BIOLOGICAL: Human Allogeneic Bone-Marrow-Derived Mesenchymal Stromal Cell Product (StromaForte)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Sarcoma|Ovarian Stromal Cancer|Recurrent Cervical Cancer|Recurrent Endometrial Carcinoma|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Uterine Sarcoma|Recurrent Vaginal Cancer|Recurrent Vulvar Cancer|Stage III Cervical Cancer|Stage III Endometrial Carcinoma|Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage III Uterine Sarcoma|Stage III Vaginal Cancer|Stage III Vulvar Cancer|Stage IV Endometrial Carcinoma|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Stage IV Uterine Sarcoma|Stage IV Vulvar Cancer|Stage IVA Cervical Cancer|Stage IVA Vaginal Cancer|Stage IVB Cervical Cancer|Stage IVB Vaginal Cancer
Interventions: RADIATION: stereotactic radiosurgery|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HEMOCC Study. Hemostasis in Cirrhotic Children.
Status: COMPLETED
Conditions: Esophageal and Gastric Varices|Child, Only
Interventions: OTHER: Collecting Clinical Data|OTHER: Collecting laboratory data
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop Trial
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Radiotherapy + Anti PD-1 Therapy in Patients With Locally Advanced Unresectable Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Locally Advanced Unresectable Pancreatic Adenocarcinoma
Interventions: DRUG: Nivolumab|RADIATION: Stereotactic radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination of Nilotinib (AMN107) and RAD001 in Patients With Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: NILOTINIB|DRUG: EVEROLIMUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suture Granuloma in Body Contouring Surgery
Status: COMPLETED
Conditions: Skin Laxity of Abdomen, Thighs, Chest, Back, and Neck
Interventions: DEVICE: Absorbable sutures
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: ProQuad Dose Selection Study (V221-011)(COMPLETED)
Status: COMPLETED
Conditions: Measles|Mumps|Rubella|Varicella
Interventions: BIOLOGICAL: Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live|BIOLOGICAL: Comparator: M-M-R II|BIOLOGICAL: Comparator: PUVV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Dose Safety Study of SRX246 Capsules in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: SRX246
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: To Study the Impact of Radiation Treatment After Surgery in Patient With Locally Advanced Thyroid Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer Stage IV|Radiation Toxicity
Interventions: RADIATION: Intensity Modulated Radiotherapy|PROCEDURE: Surgery alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Application of Poly-herbal Powder for Treating Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris
Interventions: OTHER: Mixed powder of Lens culinaris, Curcuma longa, Mentha arvensis, Azadirachta indica, and Trigonella foenumgraecum.|OTHER: Cicer arietinum powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 8-Week Atopic Dermatitis (AD) Treatment Study
Status: COMPLETED
Conditions: Atopic Dermatitis Eczema
Interventions: DRUG: Investigational OTC Cream|DRUG: 0.05% Desonide|OTHER: Placebo Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin
Status: COMPLETED
Conditions: Healthy Adults
Interventions: DIETARY_SUPPLEMENT: Crucera-SGS|DIETARY_SUPPLEMENT: Meriva 500-SF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Reparation of Cartilage Injuries in the Human Knee by Implantation of Fresh Human Allogenic Chondrocytes
Status: COMPLETED
Conditions: Cartilage Injuries in the Human Knee
Interventions: PROCEDURE: Human allogenic chondrocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates
Status: COMPLETED
Conditions: Intracranial Thrombosis
Interventions: PROCEDURE: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequential Therapy for Hypogonadotropic Hypogonadism
Status: COMPLETED
Conditions: Hypogonadotropic Hypogonadism|Kallmann Syndrome
Interventions: DRUG: Traditional intervention for HH using HCG and FSH|DRUG: Sequential intervention for HH using HCG and FSH|DRUG: Sequential intervention for HH using HCG and FSH plus zinc
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 3 Clinical Trial of CartiLife® in Korea
Status: ACTIVE_NOT_RECRUITING
Conditions: Articular Cartilage Defect|Articular Cartilage Degeneration
Interventions: DRUG: Autologous Chondrocyte Implantation (CartiLife®)|PROCEDURE: Microfracture Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thermogenic Silencer Regulatory Factors in Humans
Status: NOT_YET_RECRUITING
Conditions: Obesity|Metabolic Disease|Cold Exposure
Interventions: OTHER: Cold Vest Exposure Period|OTHER: Rewarming Exposure Period|OTHER: Fasting
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Adapting an Effective CBT for Comorbidity to a Computer-Delivered Format
Status: COMPLETED
Conditions: Generalized Anxiety Disorder|Panic Disorder|Social Anxiety|Alcohol Use Disorder
Interventions: BEHAVIORAL: Computer-based VC-CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Polyglucosamine L112 in Overweight and Obese Subjects
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Polyglucosamine L112|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
Status: COMPLETED
Conditions: Abdominal Pain|Irritable Bowel Syndrome
Interventions: OTHER: Usual care|OTHER: Pain Neuroscience education|OTHER: Extra care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Remote Ischemic Conditioning on Cerebral Hemodynamics in Patients With Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of AC699 in Patients With Estrogen Receptor Positive/Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Locally Advanced or Metastatic Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: AC699
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Salvage Radiotherapy Combined With Androgen Deprivation Therapy (ADT) With or Without Rezvilutamide in the Treatment of Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Biochemical Recurrence
Interventions: DRUG: Rezvilutamide|DRUG: Androgen deprivation therapy (ADT)|RADIATION: SRT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact on Skin (Injection Site) Reactions of Taking an Antihistamine (Zyrtec®) or Placebo Prior to Daily Injections of Copaxone®.
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DRUG: glatiramer acetate injection with oral cetirizine hydrochloride|DRUG: glatiramer acetate with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cardiac Fixation During PET Using a New Drug Within Amyloid Cardiac Injuries.
Status: TERMINATED
Conditions: Cardiac Amyloidosis
Interventions: DRUG: PET with 18 F-Flutemetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) in Healthy Women.
Status: COMPLETED
Conditions: Drug Interactions|Contraception|Pharmacokinetics
Interventions: DRUG: Norgestimate; Ethinyl Estradiol; Folic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Resistant Ovarian Cancer, Olaparib and Liposomal Doxorubicin
Status: COMPLETED
Conditions: Advanced Ovarian Cancer
Interventions: DRUG: Olaparib|DRUG: Pegylated Liposomal Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Sedation During Endoscopy in Children
Status: COMPLETED
Conditions: Failed Moderate Sedation During Procedure
Interventions: DRUG: Ketamine and Midazolam|DRUG: Propofol and Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose:
Clinical trial: An Open-Label, Long-term Study to Assess the Immunogenicity of LINZESS® (Linaclotide) Administered Orally to Adult Participants With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation
Status: COMPLETED
Conditions: Irritable Bowel Syndrome With Constipation|Chronic Idiopathic Constipation
Interventions: DRUG: Linaclotide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Daily Adaptive RadioTherapy in Postoperative HypofrActionated Salvage radiothERapy for Prostate Cancer Patients
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: RADIATION: Daily Adaptive RadioTherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weekly Docetaxel and Bortezomib in the Treatment of Advanced Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV PAPAVERINE Prior to Propess for Labor Induction
Status: NOT_YET_RECRUITING
Conditions: Induced Vaginal Delivery
Interventions: DRUG: Papaverine|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blue Light Device for Pain Therapy
Status: COMPLETED
Conditions: Low Back Pain|Low Back Pain, Recurrent|Musculoskeletal Pain|Chronic Pain
Interventions: DEVICE: Pain Relief Patch|DEVICE: Control PRP device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout
Status: ACTIVE_NOT_RECRUITING
Conditions: Gout
Interventions: DRUG: SHR4640|DRUG: Allopurinol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease
Status: COMPLETED
Conditions: Sickle Cell Disease
Interventions: DRUG: Hydroxyurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Clinical Trial to Evaluate the Ongoing Pregnancy Rate With OXO-001 in IVF/ICSI With Donor Oocytes.
Status: COMPLETED
Conditions: Infertility, Female|Infertility
Interventions: DRUG: OXO-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Perioperative Opioid Consumption Following Pectoral Nerve Block for Breast Cancer Surgery
Status: COMPLETED
Conditions: Nerve Block|Mastectomy
Interventions: DRUG: Lidocaine 1% with epinephrine 1/400000|OTHER: sham block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of C-reactive Protein Point-of-care Testing on Antibiotic Prescribing for Acute Respiratory-tract Infections At Primary Care Facilities in Rural China
Status: NOT_YET_RECRUITING
Conditions: Antibiotic Prescribing for Acute Respiratory-tract Infections
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment Of Constipation Due To Opioids Being Taken For Persistent Non-Cancer Pain
Status: COMPLETED
Conditions: Bowel Dysfunction|Constipation
Interventions: DRUG: alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer
Status: TERMINATED
Conditions: Recurrent Hypopharyngeal Squamous Cell Carcinoma|Recurrent Laryngeal Squamous Cell Carcinoma|Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Recurrent Oral Cavity Squamous Cell Carcinoma|Recurrent Oropharyngeal Squamous Cell Carcinoma|Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage III Hypopharyngeal Squamous Cell Carcinoma|Stage III Laryngeal Squamous Cell Carcinoma|Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma|Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage III Oral Cavity Squamous Cell Carcinoma|Stage III Oropharyngeal Squamous Cell Carcinoma|Stage IVA Hypopharyngeal Squamous Cell Carcinoma|Stage IVA Laryngeal Squamous Cell Carcinoma|Stage IVA Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVA Oral Cavity Squamous Cell Carcinoma|Stage IVA Oropharyngeal Squamous Cell Carcinoma|Stage IVB Hypopharyngeal Squamous Cell Carcinoma|Stage IVB Laryngeal Squamous Cell Carcinoma|Stage IVB Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVB Oral Cavity Squamous Cell Carcinoma|Stage IVB Oropharyngeal Squamous Cell Carcinoma|Stage IVC Hypopharyngeal Squamous Cell Carcinoma|Stage IVC Laryngeal Squamous Cell Carcinoma|Stage IVC Nasopharyngeal Keratinizing Squamous Cell Carcinoma|Stage IVC Oral Cavity Squamous Cell Carcinoma|Stage IVC Oropharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Stereotactic Body Radiation Therapy|DEVICE: Positron Emission Tomography|DEVICE: Computed Tomography|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propofol Versus the Use of Dexmedetomidine as a Sedative Agent for Colonosopy
Status: UNKNOWN
Conditions: Colonic Diseases
Interventions: DRUG: Propofol|DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Gray Zone Approach of Rotational Thromboelastometry for Predicting Postoperative Bleeding in Cardiac Surgical Patients
Status: UNKNOWN
Conditions: Other Functional Disturbances Following Cardiac Surgery|Postoperative Hemorrhage|Coagulation Defect; Bleeding
Interventions: DEVICE: ROTEM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Left Ventricular Reverse Remodeling In Aortic Valve Replacement With Single Strip Pericardium Versus Mechanical Valve
Status: UNKNOWN
Conditions: Aortic Valve Stenosis|Aortic Stenosis|Valve Stenoses, Aortic|Aortic Valve Calcification
Interventions: PROCEDURE: Single Strip Pericardium|PROCEDURE: Mechanical Prosthetic Valve
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lung-protective Mechanical Ventilation for Abdominal Laparoscopic Surgeries
Status: COMPLETED
Conditions: Mechanical Ventilation Complication
Interventions: PROCEDURE: Lung-protective mechanical ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Two Needles (19G Flex Versus 22G Standard) for Pancreatic Solid Tumors Diagnosis
Status: COMPLETED
Conditions: Adenocarcinoma of Head of Pancreas
Interventions: DEVICE: puncture of head of pancreas|DEVICE: puncture of head of pancreas
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy Subjects
Status: COMPLETED
Conditions: Renal Insufficiency|Healthy
Interventions: DRUG: ACT-541468
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Exploratory Study of the Cutaneous Penetration of Biodegradable Polymeric Microparticles in Atopic Dermatitis
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: DRUG: Biodegradable and biocompatible polymeric microparticles containing a fluorochrome applied to the skin followed by a skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Computer-guided vs. Conventional Cortical Shell Technique for Horizontal Augmentation
Status: COMPLETED
Conditions: Alveolar Bone Resorption|Horizontal Ridge Deficiency
Interventions: PROCEDURE: Augmentation of horizontal deficient anterior maxilla with a cortical shell harvested from a chin|PROCEDURE: Augmentation of horizontal deficient anterior maxilla with a cortical shell harvested from a chin using patient specific surgical guide then positioned with another guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fetoscopic Laser Photocoagulation in Management of Vasa Previa
Status: NOT_YET_RECRUITING
Conditions: Vasa Previa|Pregnancy Complications|Maternal; Procedure|In Utero Procedure Affecting Fetus or Newborn
Interventions: DEVICE: Fetoscopic Laser Photocoagulation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Telaglenastat Hydrochloride and Osimertinib in Treating Patients With EGFR-Mutated Stage IV Non-small Cell Lung Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lung Non-Small Cell Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Stage IV Lung Cancer AJCC v8
Interventions: PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Elastography|DRUG: Osimertinib|PROCEDURE: Positron Emission Tomography|DRUG: Telaglenastat Hydrochloride|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas
Status: TERMINATED
Conditions: Glioma
Interventions: DEVICE: NovoTTF-200A|DRUG: Temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association of Non-alcoholic Fatty Liver Disease and Coronary Artery Disease
Status: UNKNOWN
Conditions: Nonalcoholic Steatohepatitis (NASH)
Interventions: DEVICE: Transient Elastography (FibroScan), Echosens, Paris, France|DEVICE: Controlled Attenuation Parameter (CAP), Echosens, Paris, France
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness Evaluation of Panax Ginseng, Vitamins and Minerals in Improvement of Stress and Fatigue
Status: SUSPENDED
Conditions: Reduction of Stress and Fatigue
Interventions: DIETARY_SUPPLEMENT: Ginseng, vitamins, minerals|OTHER: Placebo - Gelatin capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
Status: RECRUITING
Conditions: Early Stage Breast Cancer
Interventions: OTHER: Aerobic Training|OTHER: Aerobic Training|OTHER: Aerobic Training|OTHER: Aerobic Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study of APD403 to Prevent Nausea and Vomiting After Chemotherapy
Status: COMPLETED
Conditions: CINV
Interventions: DRUG: Ondansetron|DRUG: Placebo|DRUG: Dexamethasone|DRUG: Fosaprepitant|DRUG: APD403 IV|DRUG: APD403 oral
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome
Status: TERMINATED
Conditions: Patellofemoral Pain Syndrome
Interventions: PROCEDURE: Placebo|PROCEDURE: Personalized Tourniquet System for Blood Flow Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: CROWN CORONATION: COVID-19 Research Outcomes Worldwide Network for CORONAvirus prevenTION
Status: COMPLETED
Conditions: COVID 19
Interventions: DRUG: MR or M-M-R II ® vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized CardioLink-3 Trial
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracic
Interventions: PROCEDURE: Axillary artery cannulation|PROCEDURE: Innominate artery cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Drug-drug Interaction Trial of BI 113608 in Combination With Ketoconazole and Voriconazole in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 113608|DRUG: BI 113608|DRUG: BI 113608|DRUG: Ketoconazole|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tele-physiotherapy on Post-stroke Hemiplegia Patients
Status: COMPLETED
Conditions: Hemiplegia|Muscle Spasticity
Interventions: OTHER: Conventional Physiotherapy + telephysiotherapty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Multi-Center Trial of Botox for Severe Urge Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: DRUG: Botox|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer
Status: UNKNOWN
Conditions: Oral Mucositis
Interventions: DEVICE: Caphosol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Veinplicity for Improved Venous Access: The VIVA Trial
Status: TERMINATED
Conditions: Difficult-to-access Veins for Intravenous Cannulation
Interventions: DEVICE: Veinplicity with tourniquet|DEVICE: Tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SYSTANE® BALANCE Symptoms (OSDI) & Inflammatory Biomarkers
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: OTHER: SYSTANE® BALANCE Lubricant Eye Drops|OTHER: SYSTANE® Gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Dose Exposure to Oxidized R-limonene - A Repeated Open Application Test (ROAT) Study
Status: COMPLETED
Conditions: Allergic Contact Dermatitis Due to Cosmetics
Interventions: OTHER: ROAT with oxidized R-limonene at 1%, 0.3% and 0.1%|OTHER: ROAT with oxidized R-limonene at 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Interactive Power Toothbrush With or Without App vs Manual Toothbrush
Status: COMPLETED
Conditions: Toothbrushes
Interventions: DEVICE: Oral-B Genius® 8000 power toothbrush with CrossAction brush head with smartphone app(Procter&Gamble,Ohio, USA)|DEVICE: Oral-B Genius® 8000 power toothbrush with CrossAction brush head without smartphone app(Procter&Gamble,Ohio, USA)|DEVICE: Oral B ClinicLine Pro-FlexSoft (Procter&Gamble,Ohio, USA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
Status: UNKNOWN
Conditions: Leukemia
Interventions: BIOLOGICAL: filgrastim|DRUG: asparaginase|DRUG: cytarabine|DRUG: daunorubicin hydrochloride|DRUG: dexamethasone|DRUG: etoposide|DRUG: idarubicin|DRUG: ifosfamide|DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisolone|DRUG: vindesine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Clinical Efficacy in Neoadjuvant Treatment of Locally Advanced Gastric Cancer With Different Immunotypes
Status: NOT_YET_RECRUITING
Conditions: Locally Advanced Gastric Cancer
Interventions: DRUG: Camrelizumab|DRUG: Albumin Taxol|DRUG: FLOT scheme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical and Functional Outcomes at 2 Years of 4-strand Versus 5-strand Hamstring Autograft in Anterior Cruciate Ligament Reconstruction
Status: UNKNOWN
Conditions: Physical Activity
Interventions: PROCEDURE: Strands of Hamstring Autograft in ACL reconstruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lumbar Manipulation on Intervertebral Motion, Pain, and Disability
Status: RECRUITING
Conditions: Low Back Pain
Interventions: PROCEDURE: Lumbar Manipulation|PROCEDURE: Sham Lumbar Manipulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Antivascular Therapy Combined With Chemotherapy Versus Chemotherapy in Adjuvant Therapy of TNBC-BLIS Patients (BCTOP-T-A03)
Status: RECRUITING
Conditions: Breast Cancer|Triple Negative Breast Cancer
Interventions: DRUG: Antivascular therapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Catheter-Related Bloodstream Infections in the ICU With a Chlorhexidine-Impregnated Sponge (BIOPATCH)
Status: COMPLETED
Conditions: Catheter-related Bloodstream Infection
Interventions: DEVICE: Chlorhexidine-impregnated foam dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Knockout Engineered T Cells for Metastatic Renal Cell Carcinoma.
Status: WITHDRAWN
Conditions: Metastatic Renal Cell Carcinoma
Interventions: BIOLOGICAL: PD-1 Knockout T Cells|DRUG: Cyclophosphamide|DRUG: IL-2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Impairment Following Cardiac Arrest and Target Temperature Management
Status: COMPLETED
Conditions: Heart Arrest|Out-of-hospital Cardiac Arrest|Cognition Disorders|Brain Injury
Interventions: OTHER: Temperature treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Using Botox to Treat Patients With Idiopathic Clubfoot
Status: UNKNOWN
Conditions: Clubfoot
Interventions: DRUG: Botulinum Toxin (Type A) injection (10 U/Kg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Pediatric Manual Therapy in the Positional Plagiocephaly
Status: COMPLETED
Conditions: Plagiocephaly|Plagiocephaly, Nonsynostotic|Plagiocephaly, Positional
Interventions: PROCEDURE: Pediatric Manual Therapy|PROCEDURE: Educational Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Proof-of-Concept Study Evaluating EOM613 in COVID-19 Infected Patients With Severe Symptoms
Status: UNKNOWN
Conditions: COVID-19 Pneumonia|COVID-19 Respiratory Infection|COVID-19 Acute Respiratory Distress Syndrome
Interventions: DRUG: EOM613
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: DZD9008+AZD4205
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Taxifolin/Ergothioneine and Immune Biomarkers in Healthy Volunteers (TaxEr)
Status: ACTIVE_NOT_RECRUITING
Conditions: Antioxidative Stress|Cold|Influenza|Aging|Inflammation
Interventions: DIETARY_SUPPLEMENT: Taxifolin|DIETARY_SUPPLEMENT: Ergothioneine|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Linezolid for the Treatment of Infections Caused by Methicillin Resistant Staphylococcus Aureus in Japan
Status: COMPLETED
Conditions: Infections, Nosocomial
Interventions: DRUG: linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Helicobacter Pylori Eradication and Follow-up
Status: RECRUITING
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Rabeprazole|DRUG: Bismuth potassium citrate|DRUG: Metronidazole|DRUG: Clarithromycin|DRUG: Levofloxacin|DRUG: Amoxicillin|DRUG: Metronidazole|DRUG: Doxycycline|DRUG: Tetracycline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater
Status: TERMINATED
Conditions: Optic Nerve Diseases
Interventions: DRUG: Zyvox - linezolid|DRUG: Matched control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Heart Rate Variability Biofeedback Training Versus a Meditation Program in Reducing Stress Levels in University Undergraduate Students.
Status: NOT_YET_RECRUITING
Conditions: Stress|Anxiety State
Interventions: BEHAVIORAL: Heart rate variability biofeedback training|BEHAVIORAL: Guided meditation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT