pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Antiarrhythmic Therapy Versus Catheter Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Atrial Fibrillation|Hypertrophic Cardiomyopathy
Interventions: PROCEDURE: RF catheter ablation|DRUG: Antiarrhythmic drugs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thrombus Aspiration Before Standard Primary Angioplasty Improves Myocardial Reperfusion in Acute Myocardial Infarction.
Status: COMPLETED
Conditions: Acute Myocardial Infarction
Interventions: DEVICE: Coronary thrombus aspiration catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardiac Fibroblast Activation Detected by 68Ga-FAPI PET/MR
Status: COMPLETED
Conditions: Myocardial Remodeling After AMI
Interventions: DIAGNOSTIC_TEST: 68Ga-FAPI PET/MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hormone Evaluation in Artificial Reproductive Technology
Status: COMPLETED
Conditions: Female Infertility
Interventions: DRUG: Follitropin alpha|DRUG: Menotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study in Subjects With Human Papillomavirus 16 or 18 Associated Cervical Intraepithelial Neoplasia Grade 2 or 3
Status: NOT_YET_RECRUITING
Conditions: Human Papillomavirus Associated Intraepithelial Neoplasia|Cervical Intraepithelial Neoplasia Grade 2/3|Human Papillomavirus Type 16 Infection|Human Papillomavirus Type 18 Infection
Interventions: BIOLOGICAL: RG002 injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Performance of a Patellofemoral Brace
Status: UNKNOWN
Conditions: Patellofemoral Pain Syndrome|Patellar Instability
Interventions: DEVICE: kneeSOFT500
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Implementation of Indication Criteria for Total Knee Replacement in Osteoarthritis (Value-based TKR)
Status: COMPLETED
Conditions: Knee Osteoarthritis|Arthroplasty, Replacement, Knee
Interventions: OTHER: Digital decision aid for physicians and patients|OTHER: Routine care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
Status: COMPLETED
Conditions: Hiv|Tobacco Smoking
Interventions: DEVICE: TBS|DEVICE: Sham TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: 2-Hour Dispensing Evaluation of Samfilcon A Lenses With EPG01 Packaging Solution Compared to Commercially Available B+L Ultra Lenses
Status: COMPLETED
Conditions: Contact Lens Wearer
Interventions: DEVICE: samfilcon A Lenses with EPG01 Packaging Solution|DEVICE: B+L Ultra Lenses
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study for Antibiotic Impregnated Calcium Sulfate Beads as Prophylaxis for Surgical Site Infection
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DEVICE: Stimulan Rapid Cure|DRUG: Vancomycin|DRUG: Tobramycin|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Non-myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (NST) for Patients With Refractory Crohn's Disease
Status: TERMINATED
Conditions: Crohn's Disease
Interventions: BIOLOGICAL: Allogeneic Stem Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Epilepsy by Reducing Neonatal Encephalopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Neonatal Encephalopathy|Epilepsy|Newborn Morbidity
Interventions: COMBINATION_PRODUCT: Intra-partum care bundle invoking 4 elements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Encore PFO Closure Device - The PerFOrm Trial
Status: RECRUITING
Conditions: Patent Foramen Ovale|Cryptogenic Stroke
Interventions: DEVICE: Encore PFO closure device|DEVICE: FDA-approved PFO closure device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacists and Pharmacy Technicians to Improve Admission Medication History Accuracy
Status: COMPLETED
Conditions: Adverse Drug Events
Interventions: OTHER: Pharmacist obtains admission medication history|OTHER: Pharmacy technician obtains admission medication history
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Effect of Clear Aligner Attachment Design on Extrusion of Maxillary Lateral Incisors
Status: COMPLETED
Conditions: Maxillary Lateral Incisor Malocclusion
Interventions: DEVICE: Incisally-beveled attachment|DEVICE: Gingivally-beveled attachment|DEVICE: Optimized attachment|DEVICE: Horizontal attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: CBD for the Treatment of Alcohol Use Disorder
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy in Castration Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer|Castration-Resistant Prostate Cancer
Interventions: DRUG: Transdermal Testosterone|DRUG: Standard of Care, Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified Versus Conventional Serratus Anterior Plane Block
Status: RECRUITING
Conditions: Postoperative Pain, Acute
Interventions: DRUG: 25 ml of bupivacaine 0.25% via serratus anterior block|DRUG: 25 ml of bupivacaine 0.25% via modified serratus anterior palne block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Thyroidectomy
Status: RECRUITING
Conditions: Thyroid Disease|Hypoparathyroidism Postprocedural
Interventions: DRUG: Autofluorescent detection + Injection of indocyanine green|PROCEDURE: Gold standard of visual identification and evaluation of viability of the parathyroid glands.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Resistance Exercise to Improve Fatigue in Workplace (REW)
Status: COMPLETED
Conditions: Fatigue|Musculoskeletal Diseases
Interventions: OTHER: Compensatory Workplace Exercise (CWE) - Comparative Group|OTHER: Individual Resistance Exercise (IRE) - Intervention Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaccination Adjuved Against Hepatitis B in SNS Workers Typed as no Responders to Conventional Vaccines
Status: COMPLETED
Conditions: Hepatitis B|Hepatitis|Hepatitis, Viral, Human|Hepatitis B Immunization
Interventions: BIOLOGICAL: Fendrix suspension for injection Hepatitis B (rDNA) vaccine (adjuvanted, adsorbed).
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck|Human Papilloma Virus
Interventions: DRUG: docetaxel|DRUG: cisplatin|DRUG: 5-FU|RADIATION: IMRT|DRUG: cetuximab|DRUG: carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACT34-CMI -- Adult Autologous CD34+ Cells
Status: COMPLETED
Conditions: Myocardial Ischemia
Interventions: BIOLOGICAL: CLBS14 (low-dose)|BIOLOGICAL: CLBS14 (high-dose)|BIOLOGICAL: placebo injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: GV1001 Subcutaneous(SC) for the Treatment of Moderate Alzheimer's Disease (AD)
Status: WITHDRAWN
Conditions: Moderate Alzheimer's Disease
Interventions: DRUG: GV1001|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Afatinib Dimaleate and Capecitabine in Treating Patients With Advanced Refractory Solid Tumors, Pancreatic Cancer or Biliary Cancer
Status: COMPLETED
Conditions: Advanced Malignant Solid Neoplasm|Bile Duct Carcinoma|Recurrent Malignant Solid Neoplasm|Recurrent Pancreatic Carcinoma|Stage III Pancreatic Cancer AJCC v6 and v7|Stage IVA Pancreatic Cancer|Stage IVB Pancreatic Cancer
Interventions: DRUG: Afatinib Dimaleate|DRUG: Capecitabine|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INSPIRIS RESILIA Aortic Valve, Valve-in-Valve Surveillance Study
Status: SUSPENDED
Conditions: Aortic Valve Replacement
Interventions: DIAGNOSTIC_TEST: Subjects previously implanted with INSPIRIS RESILIA Model 11500A and are undergoing planned valve-in-valve treatment.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Serum on Skin Health and Signs of Aging
Status: ACTIVE_NOT_RECRUITING
Conditions: Skin Health
Interventions: OTHER: Manuka Health Eternal Renewal Regenerating Face Serum with Royal Jelly and Bee Venom
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Assessment of AMG 420 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Relapsed and/or Refractory Multiple Myeloma
Interventions: DRUG: AMG 420
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Open Angle Glaucoma|Ocular Hypertension
Interventions: DRUG: Netarsudil/Latanoprost 0.02%/0.005%|DRUG: GANFORT®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Inhaled mannitol|DRUG: Placebo Comparator: Arm B - Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Pharmacological cardioversion - Flecainide|PROCEDURE: Electrical cardioversion|DRUG: Metoprolol|DRUG: Verapamil|DRUG: Digoxin|DRUG: Pharmacological cardioversion - Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Detection of Pancreatic Cancer in Patients With Papillary and Mucinous Intracanal Tumours of the Pancreas Papillary and Mucinous Tumours of the Pancreas
Status: NOT_YET_RECRUITING
Conditions: PAPILLARY AND MUCINOUS INTRACANAL TUMORS OF THE PANCREAS
Interventions: OTHER: blood sampling at inclusion, 6 months, 1 year and 2 years. Tumor and intracystic fluid samples are taken only if a biopsy is planned following MRI results.
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Fish Oil and Inflammation in Overweight Subjects
Status: COMPLETED
Conditions: Overweight
Interventions: DIETARY_SUPPLEMENT: fish oil|DIETARY_SUPPLEMENT: olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Study to Investigate the Safety and Efficacy of MLC601 in 150 Iranian Patients After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DRUG: MLC601|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy
Status: COMPLETED
Conditions: HIV|Hyperlipidemia|Hypertriglyceridemia|HIV Infections
Interventions: DRUG: raltegravir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Cisapride in Patients With Symptomatic Gastro-Oesophageal Reflux Disease
Status: TERMINATED
Conditions: Gastroesophageal Reflux
Interventions: DRUG: Placebo|DRUG: Cisapride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Observational Study Evaluating Therapy Optimisation Using High-frequency and High-dosage Administration of Interferon-beta (Rebif®) in Multiple Sclerosis (MS) Patients
Status: COMPLETED
Conditions: Relapsing-Remitting Multiple Sclerosis
Interventions: DRUG: Interferon beta 1a
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Outpatient Temperature Monitoring for Early Detection of Febrile Neutropenia After Chemotherapy
Status: COMPLETED
Conditions: Acute Myeloid Leukemia (AML)
Interventions: DEVICE: Remote monitoring of temperature
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Bioequivalence Study Between Two Brands of Medications to Treat Cough & Cold Symptoms
Status: COMPLETED
Conditions: Bioequivalence|Healthy Volunteers
Interventions: DRUG: Tablet paracetamol, guaifenesin and phenylephrine HCL|DRUG: Vicks Active SymptoMax Plus powder for oral solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: The IGNITE Study on Concentrated Investment in Black Neighborhoods
Status: ACTIVE_NOT_RECRUITING
Conditions: Financial Stress|Economic Problems|Environmental Exposure|Health Behavior|Health, Subjective|Mental Health Wellness 1
Interventions: OTHER: Financial Well-being Interventions|OTHER: Place-based Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Metabolic Cofactor Supplementation and Hydroxychloroquine Combination in Covid-19 Patients
Status: UNKNOWN
Conditions: COVID-19
Interventions: DRUG: Hydroxychloroquine + Metabolic cofactor supplementation|DRUG: Hydroxychloroquine + Sorbitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Exogenous Ketosis During Ultra-endurance Exercise
Status: UNKNOWN
Conditions: Exercise|Ultra-endurance Running|Ketosis|Skeletal Muscle|Cognitive Function
Interventions: DIETARY_SUPPLEMENT: Ketone ester|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Clinical Use of Pathogen Reduced Red Blood Cell Suspension
Status: COMPLETED
Conditions: Oncologic Disorders|Hematologic Diseases
Interventions: BIOLOGICAL: Riboflavin+UV RBC|BIOLOGICAL: irradiated RBC
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Post Facilitation Stretch Versus Reciprocal Inhibition in Quadratus Lumborum Syndrome: a Randomized Controlled Trial
Status: RECRUITING
Conditions: Quadratus Lumborum Syndrome
Interventions: OTHER: Post Facilitation Stretch|OTHER: Reciprocal Inhibition|OTHER: Conventional Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the Safety and Efficacy of Proellex® (CDB-4124) in Premenopausal Women With Symptomatic Uterine Fibroids
Status: TERMINATED
Conditions: Uterine Fibroids
Interventions: DRUG: Proellex|DRUG: Proellex|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: GSK1550188 A 52 Week Study of Belimumab Versus Placebo in the Treatment of Subjects With Systemic Lupus Erythematosus (SLE) Located in Northeast Asia
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biological Therapy in Treating Patients With Multiple Myeloma That Has Recurred Following Bone Marrow Transplantation
Status: COMPLETED
Conditions: Multiple Myeloma and Plasma Cell Neoplasm
Interventions: BIOLOGICAL: therapeutic allogeneic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Outcomes of Once-Daily ICS/LABA/LAMA Plus PRN Respiratory Therapy Treatments in Hospitalized Patients With COPD Exacerbations
Status: UNKNOWN
Conditions: Copd
Interventions: DRUG: TRELEGY ELLIPTA 100Mcg-62.5Mcg-25Mcg/Actuation Powder for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Avelumab in Relapsed and Refractory Peripheral T-cell Lymphoma
Status: COMPLETED
Conditions: T-Cell Lymphoma Relapsed|T-Cell Lymphoma Refractory
Interventions: DRUG: Avelumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Plasma- and Endothelial DPP-4 Activity
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: sitagliptin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Human and Computer-based Quantification of Airway Stenosis From Bronchoscopic Images
Status: UNKNOWN
Conditions: Airway Obstruction
Interventions: OTHER: Human-based Quantification of Airway Stenosis|DEVICE: Computer-based Quantification of Airway Stenosis From Bronchoscopic Images.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: An Open-Label, Multi-Center, Clinical Study Evaluating the Effect of the NDE L68 StableFit® Punctal Plug on the Tear Lake
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DEVICE: NDE L68 StableFit® Punctal Plug
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in Children
Status: COMPLETED
Conditions: Urinary Tract Infection|Pyelonephritis|Cystitis
Interventions: OTHER: Cranberry-lingonberry juice|OTHER: Placebo juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate SYN115 in Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: Placebo|DRUG: Tozadenant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Gait Rehabilitation Robot of an End-Effector on Neuro-Muscular Pathway in Patients After Knee Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Knee
Interventions: DEVICE: Morning walk|DEVICE: Ground Walker
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Pharmacokinetic Profile of a Proprietary Curcumin Forumulation to a Comparator Curcumin Product
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Proprietary Curcumin Formulation|DIETARY_SUPPLEMENT: Unformulated Comparator Curcumin Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of the Autonomic Nervous System on the Outcomes of PULSEd Field Ablation to Treat Atrial Fibrillation
Status: NOT_YET_RECRUITING
Conditions: Atrial Fibrillation
Interventions: PROCEDURE: Pulmonary vein isolation exclusively with radiofrequency|PROCEDURE: Pulmonary vein isolation exclusively with pulsed field ablation|PROCEDURE: Combined pulmonary vein isolation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Selgantolimod|DRUG: Placebo|DRUG: Hepatitis B virus (HBV) OAV Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors
Status: COMPLETED
Conditions: Neurofibromatosis Type 1|Recurrent Childhood Brain Stem Glioma|Recurrent Childhood Visual Pathway Glioma|Recurrent Primary Central Nervous System Neoplasm|Refractory Primary Central Nervous System Neoplasm
Interventions: OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Xihuang Pill to Improve the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Chemotherapy Effect
Interventions: DRUG: Epirubicin, Cyclophosphamide, Xihuang Pill, Docetaxel|DRUG: Epirubicin, Cyclophosphamide, Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Length of Progesterone Supplementation Before the Transfer of Cryopreserved (Frozen)-Thawed Day 3 Embryos in an Artificial Cycle With Exogenous Estrogen and Progesterone
Status: COMPLETED
Conditions: Progesterone Supplementation
Interventions: DRUG: Progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single-Sided Deafness and Asymmetric Hearing Loss
Status: RECRUITING
Conditions: Hearing Loss, Unilateral|Hearing Loss, Sensorineural
Interventions: DEVICE: MED-EL Cochlear Implant System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Verification Protocol for the Cloud DX Vitaliti Continuous Vital Signs Monitor (VERDICT-2)
Status: COMPLETED
Conditions: Blood Pressure|Respiration|Pulse Rate|Oxygen Saturation|Temperature|Heart Rate
Interventions: DEVICE: Vitaliti Continuous Vital Sign Monitor Model CVSM-1A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lymphatic Morphology of Fontan Patients
Status: COMPLETED
Conditions: Lymphatic Abnormality|Plastic Bronchitis|Protein-Losing Enteropathies|Univentricular Heart|Congenital Heart Disease
Interventions: DIAGNOSTIC_TEST: Non-contrast MRI|DIAGNOSTIC_TEST: Cardiopulmonary exercise test
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ventricular Tachycardia (VT) Ablation or Escalated Drug Therapy
Status: COMPLETED
Conditions: Recurrent Ventricular Tachycardia
Interventions: PROCEDURE: Catheter Ablation|DRUG: Escalated Antiarrhythmic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Bi-level and Single-level ESP Block for Open Inguinal Hernia Repair
Status: NOT_YET_RECRUITING
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Erector spinae plane block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Cryotherapy Plus Acupressure and Acupuncture Versus Oral Cryotherapy for Decreasing Chemotherapy-Induced Peripheral Neuropathy From Oxaliplatin-Based Chemotherapy in Patients With Gastrointestinal Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Appendix Carcinoma|Colon Carcinoma|Esophageal Carcinoma|Gastric Carcinoma|Liver and Intrahepatic Bile Duct Carcinoma|Malignant Digestive System Neoplasm|Pancreatic Carcinoma|Rectal Carcinoma|Small Intestinal Carcinoma|Anal Carcinoma|Digestive System Carcinoma|Digestive System Neuroendocrine Tumor|Pancreatic Neuroendocrine Tumor
Interventions: PROCEDURE: Acupuncture Therapy|PROCEDURE: Acupressure Therapy|PROCEDURE: Oral Cryotherapy|OTHER: Questionnaire Administration|OTHER: Quality-of-Life Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies
Status: COMPLETED
Conditions: Narcolepsy|Hypersomnia
Interventions: DRUG: Modafinil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sleep for Stroke Management and Recovery Trial
Status: RECRUITING
Conditions: Ischemic Stroke|Sleep Apnea|Sleep Apnea, Obstructive|Stroke|CPAP|Telemedicine|Home Sleep Apnea Test|Randomized Clinical Trial|Multicenter Trial
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Fresh Versus Freeze-only After CAPA IVM on PCOS Patients
Status: COMPLETED
Conditions: PCOS|IVM|Embryo Transfer
Interventions: PROCEDURE: CAPA-Fresh|PROCEDURE: CAPA-Freeze-only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clofarabine-cyclophosphamide as Salvage Therapy for Refractory and Relapsed Acute Lymphoblastic Leukemia (ALL) Adults
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: Clofarabine, Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-Operative Impact of Nasogastric Tubes on Rates of Emesis in Infants Diagnosed With Pyloric Stenosis
Status: COMPLETED
Conditions: Pyloric Stenosis
Interventions: DEVICE: Nasogastric Tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Meloxicam [Mobic] in Juvenile Rheumatoid Arthritis (JRA)
Status: COMPLETED
Conditions: Arthritis, Juvenile Rheumatoid
Interventions: DRUG: meloxicam oral suspension|DRUG: naproxen oral suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: |Primary Purpose: TREATMENT
Clinical trial: Role of Lean-pork Within a Plant-based Dietary Pattern
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy Aging
Interventions: OTHER: Omnivorous|OTHER: Vegetarian
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Validation of a Walk-Time Limit Test (WTLT) Derived From the 6-Minute Walk Test (6-MWT) in Patients With Chronic Cardiovascular or Respiratory Diseases
Status: TERMINATED
Conditions: Chronic Obstructive Pulmonary Disease|Cardiovascular Insufficiency
Interventions: DIAGNOSTIC_TEST: 6-minute walk test|DIAGNOSTIC_TEST: Walk-Time Limit Tes|DIAGNOSTIC_TEST: Incremental shuttle walk test|DIAGNOSTIC_TEST: Endurance shuttle walk test|DIAGNOSTIC_TEST: Respiratory Functional Assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Feasibility, Acceptability, and Usability of a Tele-rehabilitation Combining Immersive Virtual Reality Exercises and Therapeutic Education for Chronic Non-specific Neck Pain
Status: RECRUITING
Conditions: Neck Pain
Interventions: DEVICE: Virtual reality|BEHAVIORAL: Therapeutic education
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Double-Blind Placebo Controlled Study of Safety,Tolerability, and Efficacy of LiRIS® in Women With Interstitial Cystitis
Status: TERMINATED
Conditions: Interstitial Cystitis
Interventions: DRUG: Lidocaine Releasing Intravesical System - LiRIS®|OTHER: LiRIS Placebo|PROCEDURE: Sham Cystoscopy Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Global Postural Reeducation on Alzheimer Disease Patients
Status: COMPLETED
Conditions: Alzheimer's Type Dementia|Cognitive Decline|Postural; Strain
Interventions: OTHER: GPR Intervention Research group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Efficacy of Manual Therapy for a Subgroup of Acute Non-specific Low Back Pain
Status: TERMINATED
Conditions: Low Back Pain
Interventions: OTHER: Spinal manipulation|OTHER: sham spinal manipulation|OTHER: Usual medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
Status: UNKNOWN
Conditions: Coronary Artery Disease|Coronary Artery Ectasia|Slow-Flow Phenomenon|Endothelial Dysfunction|Anxiety|Depression
Interventions: PROCEDURE: coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DIAGNOSTIC_TEST: Baseline ferritin level|DRUG: Lactoferrin|DRUG: Ferrous Sulfate|DIAGNOSTIC_TEST: Follow up ferritin level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Muscular Atrophy|Neuromuscular Diseases|SMA
Interventions: DRUG: taldefgrobep alfa|DRUG: Placebo|DRUG: taldefgrobep alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units
Status: TERMINATED
Conditions: Delirium|Respiratory Failure
Interventions: DRUG: Dexmedetomidine|DRUG: GABA agonist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Metastatic Triple-Negative Breast Cancer
Interventions: DRUG: Eribulin|DRUG: SDX-7320|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intervention for Self-regulation to Physical Exercise in People With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Goal intention|BEHAVIORAL: Implementation intention to initiate the behavior|BEHAVIORAL: Implementation intention to manage the goal preference (avoiding behavior or not)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomechanical and Electrophysiological Effects of Duloxetine in the Treatment of Women With Urinary Stress Incontinence
Status: COMPLETED
Conditions: Urinary Stress Incontinence
Interventions: DRUG: Duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: BIOLOGICAL: Albumin 5%|BIOLOGICAL: Albumin 20%|BIOLOGICAL: Immunoglobulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DIETARY_SUPPLEMENT: Creatine monohydrate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Particle Size, Formulation and Food on the Pharmacokinetics of GDC-0032 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: GDC-0032 Phase III Tablet|DRUG: GDC-0032 Tablet|DRUG: GDC-0032 Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Negative Pressure Wound Therapy-PICO: Cosmesis in Repeat C-Sections
Status: COMPLETED
Conditions: Hypertrophic Skin Condition of Anterior Abdomen
Interventions: DEVICE: PICO 7 dressing|OTHER: Standard wound dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study to Improve the Collaboration Between Primary and Secondary Health Care on the Treatment of Osteoporosis After a Hip Fracture.
Status: RECRUITING
Conditions: Hip Fractures|Osteoporosis|Zoledronic Acid|Ambulant Nurse|Case Manager
Interventions: PROCEDURE: Ambulant nurse-assisted administration of zoledronic acid|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gastric Capsule Examination for Iron Deficiency Anaemia
Status: COMPLETED
Conditions: Iron Deficiency Anemia
Interventions: DEVICE: Magnetically steerable pill camera (Microcam Navi, Intromedic Ltd, Seoul, Korea)|DEVICE: Flexible endoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation Of Fondaparinux (Also Called ARIXTRA) 2.5 mg Subcutaneously Once Daily For The Treatment Of Superficial Thrombophlebitis (Also Known As Superficial Vein Thrombosis)
Status: COMPLETED
Conditions: Thrombosis, Venous
Interventions: DRUG: Fondaparinux 2.5mg or placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Quercetin in Coronary Artery By-pass Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Coronary Artery Disease
Interventions: DRUG: Quercetin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Effectiveness of Transcutaneous Nerve Stimulation in Reducing Migraine Related Pain
Status: COMPLETED
Conditions: Headache, Migraine
Interventions: DEVICE: OSTNS Neurostimulator|DEVICE: Placebo OSTNS Neurostimulator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients
Status: COMPLETED
Conditions: Renal Transplantation
Interventions: DRUG: Enteric-Coated Mycophenolate Sodium (EC-MPS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A New Approach to Target the Substrates of Persistent Atrial Fibrillation: The Sequential Substrate Ablation Approach
Status: COMPLETED
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exercise, Age-Related Memory Decline, And Hippocampal Function
Status: COMPLETED
Conditions: Cognitive Deterioration|Disorder of Aging
Interventions: BEHAVIORAL: aerobic training|BEHAVIORAL: Wait list
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety Study of Cenobamate in Subjects With Normal Hepatic Function and Subjects With Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Cenobamate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of HEMAX PFS Versus EPREX/ ERYPO® in Predialysis Chronic Kidney Disease
Status: UNKNOWN
Conditions: Anemia of Chronic Kidney Disease
Interventions: BIOLOGICAL: Erythropoietin alfa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Coffee Roasting on Blood Sugar Levels in Healthy Humans
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Placebo Comparator|DIETARY_SUPPLEMENT: Light Roasted Coffee|DIETARY_SUPPLEMENT: Medium Roasted Coffee|DIETARY_SUPPLEMENT: Dark Roasted Coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Outpatient Recovery From Acute Kidney Injury Requiring Dialysis
Status: TERMINATED
Conditions: Acute Kidney Injury|Dialysis Hypotension
Interventions: OTHER: ORKID Bundled Intervention|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Systematic ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm and Halland, Sweden
Status: UNKNOWN
Conditions: Atrial Fibrillation|Stroke
Interventions: OTHER: ECG screening for atrial fibrillation using intermittent ECG recorder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of a Synbiotic Addition on Eradication Therapy of Helicobacter Pylori Infection in Children
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Bifidobacterium Animalis Oral Product|DRUG: Amoxicillin Oral Tablet|DRUG: Clarithromycin Oral Tablet|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of BAP5191 in Healthy Adults Following Topical Application of Repeat Doses
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BAP5191
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: A Fifty-two-week Study to Evaluate the Safety of Saredutant in Adult and Elderly Patients With Depression
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: DRUG: Saredutant succinate (SR48968C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Efficacy of a Spousal Support Enhanced Weight Loss Program on Weight Loss Among African American Men
Status: COMPLETED
Conditions: Overweight|Weight Loss|Obese
Interventions: BEHAVIORAL: Attends with partner|BEHAVIORAL: Couples Skill Training|BEHAVIORAL: Face to face group sessions|BEHAVIORAL: Self Monitor|OTHER: Notebook|BEHAVIORAL: Feedback
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sequential Belimumab and T-cell Based Therapy in SLE
Status: RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: Belimumab Injection [Benlysta]
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Sorafenib PK in Patients With Advanced HCC and Child-Pugh B
Status: TERMINATED
Conditions: BCLC Stage C HCC|CP-B Liver Cirrhosis
Interventions: DRUG: Sorafenib|OTHER: Midazolam clearance test|OTHER: CYP cocktail clearance test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: Acute Erythroid Leukemia|Acute Megakaryoblastic Leukemia|Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome|Chronic Myelomonocytic Leukemia|Myelodysplastic Syndrome|Myelodysplastic Syndrome With Excess Blasts|Myelodysplastic Syndrome With Ring Sideroblasts|Recurrent Adult Acute Myeloid Leukemia|Refractory Anemia
Interventions: DRUG: Azacitidine|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of GNC-038, a Tetra-specific Antibody, in Patients With Central Nervous System Lymphoma (PCNSL) and Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)
Status: RECRUITING
Conditions: Primary Central Nervous System Lymphoma|Secondary Central Nervous System Lymphoma
Interventions: DRUG: GNC-038
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Accuracy of WEARable TECHnology Single-lead ECG in Detecting Cardiac Arrhythmias
Status: COMPLETED
Conditions: Cardiac Arrhythmia|Atrial Fibrillation
Interventions: DEVICE: Group A|DEVICE: Group B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: CMF regimen|DRUG: docetaxel|DRUG: doxorubicin hydrochloride|DRUG: tamoxifen citrate|PROCEDURE: autologous bone marrow transplantation|PROCEDURE: surgical procedure|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: DRUG: irinotecan hydrochloride|DRUG: vincristine sulfate|RADIATION: iobenguane I 131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT