pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: 68Ga-FAPI PET/CT in Liver Fibrosis Patients
Status: UNKNOWN
Conditions: Liver Fibrosis|Positron Emission Tomography
Interventions: DRUG: 68Ga-FAPI-04
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy and Safety of HD-6277 in Adult Patients With Inadequate Control of Type 2 Diabetes Mellitus by Diet and Exercise
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HD-6277|DRUG: HD-6277|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Application on Anti-TNF Drug Adherence of Ankylosing Spondylitis Patients: Pilot Study
Status: COMPLETED
Conditions: Ankylosing Spondylitis|Spondylitis, Ankylosing
Interventions: OTHER: Experimental|OTHER: control
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CyberKnife® as Monotherapy or Boost SBRT for Intermediate or High Risk Localized Prostate Cancer
Status: RECRUITING
Conditions: Prostate Adenocarcinoma
Interventions: RADIATION: CyberKnife|OTHER: Androgen Deprivation Therapy (ADT)|RADIATION: Intensity Modulated radiation therapy (IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Palliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Pancreatic Cancer|Periampullary Adenocarcinoma
Interventions: RADIATION: Stereotactic Body Radiation Therapy (SBRT)|RADIATION: Stereotactic Body Radiation Therapy (SBRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing Bunionectomy
Status: COMPLETED
Conditions: Pain, Postoperative|Bunion
Interventions: DRUG: FX301|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Non-interventional Survey to Evaluate Injection Intervals and Treatment Modalities of Botulinum Toxin A (BoNT-A) in Adult Patients Suffering From Upper Limb Spasticity After Stroke
Status: TERMINATED
Conditions: Upper Limb Spasticity After Stroke
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults
Status: COMPLETED
Conditions: Healthy, Young Adults
Interventions: BEHAVIORAL: RLIC|BEHAVIORAL: Sham conditioning|BEHAVIORAL: Muscle strength training|BEHAVIORAL: Driving training|BEHAVIORAL: Balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy
Status: COMPLETED
Conditions: Prostate Cancer|Sexual Dysfunction
Interventions: DRUG: Tadalafil|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Exercise on Obstructive Sleep Apnea Severity in Elderly
Status: UNKNOWN
Conditions: Obstructive Sleep Apnea|Sleep-disordered Breathing|Sleep Disorder; Breathing-Related
Interventions: OTHER: Aquatic exercise training program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Lymphocyte-Rich Classical Hodgkin Lymphoma|Recurrent Lymphocyte-Depleted Classical Hodgkin Lymphoma|Recurrent Mixed Cellularity Classical Hodgkin Lymphoma|Recurrent Nodular Sclerosis Classical Hodgkin Lymphoma|Refractory Lymphocyte-Depleted Classical Hodgkin Lymphoma|Refractory Mixed Cellularity Classical Hodgkin Lymphoma|Refractory Nodular Sclerosis Classical Hodgkin Lymphoma
Interventions: DRUG: Carboplatin|DRUG: Etoposide|DRUG: Ifosfamide|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Animation- Versus Text-based Computer-tailored Game Intervention to Prevent Alcohol Consumption in Adolescents
Status: COMPLETED
Conditions: Alcohol Drinking|Binge Drinking|Adolescent Behavior
Interventions: BEHAVIORAL: Alerta Alcohol|BEHAVIORAL: Alerta Alcohol 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Diosmectite (Smecta®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Individualization of Nutritive Sensory Support Of Radiation Therapy
Status: COMPLETED
Conditions: Radiotherapy; Complications|Head and Neck Cancer
Interventions: DIETARY_SUPPLEMENT: Oral nutritional supplements (ONS) with a cooling effect + ONS without a sensor component and taste + standard diet|DIETARY_SUPPLEMENT: ONS without a sensor component and taste + standard diet|DIETARY_SUPPLEMENT: Standard diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Pazopanib and Paclitaxel in Advanced Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: pazopanib|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Different Administration Regimens of Ceftazidime/Avibactam and Clinical Outcomes
Status: RECRUITING
Conditions: Anti-Infective Agent
Interventions: DRUG: CAZ/AVI|DRUG: CAZ/AVI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: DRUG: Vedolizumab|DRUG: Tofacitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asthma and Health Literacy in Newcomer Communities in the Greater Vancouver Area
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: patient role played community video|BEHAVIORAL: both videos group|BEHAVIORAL: Pamphlet group|BEHAVIORAL: physician-led knowledge video|BEHAVIORAL: Community video group|BEHAVIORAL: knowledge video
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Use of Simvastatin as a Steroid Sparing Agent for Uveitis Patients
Status: UNKNOWN
Conditions: Uveitis
Interventions: DRUG: Simvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia
Status: COMPLETED
Conditions: Presbyopia
Interventions: DRUG: AGN-199201 ophthalmic solution|DRUG: AGN-190584 ophthalmic solution|DRUG: AGN-190584 vehicle|DRUG: AGN-199201 + AGN-190584 Combination|DRUG: AGN-199201 vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cenicriviroc on HIV Neurocognitive Impairment
Status: COMPLETED
Conditions: AIDS Dementia Complex|HIV-1-Associated Cognitive Motor Complex|Human Immunodeficiency Virus
Interventions: DRUG: cenicriviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DORA and LP in Alzheimer's Disease Biomarkers
Status: RECRUITING
Conditions: Alzheimer Disease
Interventions: DRUG: Lemborexant 10 mg|DRUG: Lemborexant 20mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Impact of Lactobacillus Rhamnosus GG on Proton Pump Inhibitor-Induced Gut Dysbiosis
Status: RECRUITING
Conditions: Healthy
Interventions: DRUG: Omeprazole|DIETARY_SUPPLEMENT: Lactobacillus rhamnosus GG|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study to Assess MEDI4736 With Either AZD9150 or AZD5069 in Advanced Solid Tumors & Relapsed Metastatic Squamous Cell Carcinoma of Head & Neck
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: AZD9150|DRUG: MEDI4736|DRUG: AZD5069|DRUG: tremelimumab (treme)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Study in Chronic Kidney Disease (Extension From Study 14817)
Status: COMPLETED
Conditions: Hyperphosphatemia
Interventions: DRUG: Fosrenol (Lanthanum Carbonate, BAY77-1931)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis
Status: RECRUITING
Conditions: Bacterial Vaginosis
Interventions: DRUG: Metronidazole vaginal suppositories|DRUG: Metronidazole vaginal suppositories and Probiotics(Umeta-mimi)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Early Therapies During Non-hospitalized Outpatient Window for COVID-19
Status: COMPLETED
Conditions: COVID-19
Interventions: DRUG: Lopinavir/Ritonavir 400 mg/100 mg|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Nutritional Therapy in Late-onset Pompe Disease
Status: NOT_YET_RECRUITING
Conditions: Pompe Disease|Muscle Loss|Obesity|Nutrition Poor|Lysosomal Storage Diseases|Glycogen Storage Disease Type II|Glycogen Storage Disease Type II Late Onset|Glycogen Storage Disease Type II, Adult
Interventions: DIETARY_SUPPLEMENT: Multi-ingredient supplement (PDT-MIS)|DIETARY_SUPPLEMENT: Placebo (PLA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Studying the Effectiveness and Implementation of Sudarshan Kriya Yoga for Canadian Veterans With PTSD
Status: RECRUITING
Conditions: PTSD|Depressive Symptoms|Anxiety|Pain|Quality of Life|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Sudarshan Kriya Yoga (SKY)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Mulligan Mobilization Technique And Cervical Stabilization Training in Patients With Chronic Neck Pain
Status: UNKNOWN
Conditions: Chronic Neck Pain
Interventions: OTHER: Home exercise|OTHER: Mulligan mobilization|OTHER: Cervical stabilization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MEG Study of Acute STX209 Effects in ASD
Status: COMPLETED
Conditions: Autism Disorder
Interventions: DRUG: STX209 (15mg)|DRUG: placebo|DRUG: STX209 (30mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Exploratory Study in the Relief of Drug-induced Xerostomia Associated With Hyposialia
Status: COMPLETED
Conditions: Drug-induced Xerostomia
Interventions: DEVICE: Tested product : DC161-DP0291|DEVICE: Tested product : DC161-DP0292|DEVICE: Tested product : DC161-DP0293|DEVICE: Reference product: solution for oromucosal sprays
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: PK Trial of Sorafenib & Erlotinib in Patients With Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: Erlotinib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation
Status: COMPLETED
Conditions: Respiratory Distress Syndrome, Adult|Bronchiolitis Obliterans|Pneumonia
Interventions: DRUG: etanercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Early Physical Therapy Intervention for Patients With Dizziness After a Sports-Related Concussion
Status: COMPLETED
Conditions: Brain Concussion|Dizziness
Interventions: OTHER: Physical Therapy Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis
Status: COMPLETED
Conditions: Severe Sepsis
Interventions: DRUG: eritoran tetrasodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Targeted Investigation of Microbiome Elimination
Status: TERMINATED
Conditions: Atopic Dermatitis
Interventions: BIOLOGICAL: S. hominis A 9 Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pelvic Floor Exercises During Gestation in the Prevention of Urinary Incontinence and Pelvic Floor Muscle Dysfunction
Status: COMPLETED
Conditions: Pelvic Floor Abnormalities
Interventions: PROCEDURE: Pregnants for receive the physical therapy guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Boswellia Serrata Extract in Acute Diarrhea
Status: COMPLETED
Conditions: Acute Diarrhea|Boswellia Serrata
Interventions: DIETARY_SUPPLEMENT: lecithin-based delivery form of Boswellia serrata|COMBINATION_PRODUCT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ixazomib Citrate, Pomalidomide, Dexamethasone, Stem Cell Transplant in Treating Relapsed or Refractory Multiple Myeloma
Status: COMPLETED
Conditions: Recurrent Plasma Cell Myeloma|Refractory Plasma Cell Myeloma
Interventions: PROCEDURE: Autologous Hematopoietic Stem Cell Transplantation|DRUG: Dexamethasone|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|DRUG: Pomalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Coupler-based Fitting Approach for Experienced Users Receiving Replacement Hearing Aids
Status: COMPLETED
Conditions: Hearing Loss
Interventions: DEVICE: Study 1 - ITE hearing aids|DEVICE: Study 1 - BTE hearing aids|DEVICE: Study 3 (open-fit comparison)|DEVICE: Study 3 (closed-fit comparison)|DEVICE: Study 3 (experimental open-fit)|DEVICE: Study 3 (experimental closed-fit)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating the Safety, Tolerability, Pharmacokinetic and Efficacy of HLX301(TIGIT×PDL1 Bispecific) in Locally Advanced/Metastatic Solid Tumors or Lymphoma
Status: RECRUITING
Conditions: Advanced Tumors|Lymphoma|Metastatic Tumors
Interventions: DRUG: HLX301
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy of Fluticasone Furoate/Vilanterol (FF/VI) Inhalation Powder 100/25 mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50 mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: FF/VI 100/25 Inhalation Powder NDPI|DRUG: Fluticasone Propionate/Salmeterol 250/50 Inhalation Powder ACCUHALER/DISKUS|DRUG: Placebo Inhalation Powder NDPI|DRUG: Placebo Inhalation Powder ACCUHALER/DISKUS|DRUG: Salbutamol as needed
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress.
Status: COMPLETED
Conditions: Stress|Signs and Symptoms, Digestive|Blood Pressure|Increased Secretion of Gastrin
Interventions: OTHER: Cold espresso|OTHER: Hot instant coffee|OTHER: Cold instant coffee|OTHER: Hot filter coffee
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Genetic Testing and Motivational Counseling for FH
Status: RECRUITING
Conditions: Hypercholesterolemia, Familial|Hypercholesterolemia, Familial, 1|Hypercholesterolemia, Familial, 2|Hypercholesterolemia, Familial, 3|Hypercholesterolemia, Familial, 4|Hypercholesterolemia, Familial, 4, Autosomal Recessive|Familial Hypercholesterolemia With Hyperlipemia|Hypercholesterolemia, Autosomal Dominant, Type B|Hypercholesterolemia, Autosomal Dominant|Hypercholesterolemia, Autosomal Dominant, 3|Apolipoprotein B-100, Familial Defective|Genetic Testing|Motivational Interviewing|Therapeutic Adherence|Therapeutic Adherence and Compliance|Treatment Adherence|Medication Adherence|Treatment Adherence and Compliance|Patient Adherence|Compliance|Patient Compliance|Familial Hypercholesterolemia|Familial Hypercholesterolemia - Heterozygous|Adherence, Patient|Adherence, Medication|Adherence
Interventions: GENETIC: Genetic Testing|BEHAVIORAL: Motivational Counseling|DIAGNOSTIC_TEST: Lipid analysis|OTHER: Consultation with a cardiologist-lipidologist (correction of therapy, lifestyle, diet)|OTHER: Visit 1|OTHER: Visit 2|OTHER: Visit 3|OTHER: Visit 4
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Metabolism and Pharmacokinetics of [14C]-DK-AH 269 CL in 12 Healthy Male Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-DK-AH 269 CL, solution for infusion|DRUG: [14C]-DK-AH 269 CL, drinking solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Techniques of Haemostasis After Cervical Conization
Status: COMPLETED
Conditions: Cervical Intraepithelial Neoplasia|Cervix Neoplasm
Interventions: PROCEDURE: Vaginal Packing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Deflazacort in Dysferlinopathies
Status: COMPLETED
Conditions: LGMD2B|Miyoshi Myopathy|Dysferlinopathy
Interventions: DRUG: deflazacort|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Erlotinib in Treating Patients With Recurrent or Metastatic Skin Squamous Cell Carcinoma
Status: COMPLETED
Conditions: Metastatic Skin Squamous Cell Carcinoma|Recurrent Skin Squamous Cell Carcinoma
Interventions: DRUG: Erlotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Multi-site, Individually Randomized, Controlled Translation Trial of Integrated and Comprehensive Care Strategies to Reduce Cardiovascular Disease (CVD) Risk Among 1,120 Type 2 Diabetes Mellitus(T2DM) Patients in South Asia
Status: UNKNOWN
Conditions: Type 2 Diabetes Mellitus|Hypertension|Dyslipidaemia
Interventions: OTHER: Care Coordinator + Decision Support Software|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Prospective and Retrospective Observational Evaluation of Real World Outcome of Unfit AML Patients Treated With the Combination Venetoclax Plus Hypomethylating Agents, Under the Italian Law No.648/96
Status: RECRUITING
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Venetoclax plus HMA
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors
Status: UNKNOWN
Conditions: Recurrent Childhood Brain Tumor
Interventions: DEVICE: Tumor biology testing|DRUG: Temozolomide|DRUG: Etoposide|DRUG: Sorafenib|DRUG: Everolimus|DRUG: Erlotinib|DRUG: Dasatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Randomized Study Comparing ePTFE Versus Dacron Graft for Anterior Sector Venous Drainage in Right Lobe Living Donor Liver Transplantation
Status: UNKNOWN
Conditions: Patency and Infection Rates Due to Usage of PTFE vs.Dacron Grafts
Interventions: PROCEDURE: Active Comparator: ePTFE graft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Myeloid Leukemia, in Relapse|NPM1 Mutation
Interventions: DRUG: Venetoclax+azacitidine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pathways for the Management of Acute Coronary Syndromes - Phase 3,CPACS-3
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: BEHAVIORAL: quality improvement initiatives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia
Status: RECRUITING
Conditions: Acute Myeloid Leukemia, Adult
Interventions: DRUG: ADI-PEG 20
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Neoadjuvant Chemotherapy + Surgery vs. Surgery for Bulky Stage I/II Cervical Cancer
Status: TERMINATED
Conditions: Cervical Neoplasms
Interventions: DRUG: neoadjuvant chemotherapy + radical hysterectomy|PROCEDURE: radical hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Long-term Impact of a Light Intervention on Sleep and Cognition in Mild Cognitive Impairment
Status: RECRUITING
Conditions: Mild Cognitive Impairment|Alzheimer's Disease
Interventions: DEVICE: Lighting Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Immunogenicity and Efficacy of NDV-3A Vaccine in Preventing Recurrent Vulvovaginal Candidiasis
Status: COMPLETED
Conditions: Vulvovaginal Candidiasis
Interventions: BIOLOGICAL: NDV-3A|BIOLOGICAL: NDV-3|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Metabolism Research of KLK Treating Acute Cerebral Ischemic Stroke: Focus on Drug Frequency-Efficacy Relationship
Status: UNKNOWN
Conditions: Cerebral Infarction
Interventions: DRUG: Human Urinary Kallidinogenase for Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Hyaluronic Acid Gel in Intraosseous Defects
Status: COMPLETED
Conditions: Periodontitis
Interventions: PROCEDURE: Hyaluronic acid gel application|PROCEDURE: Placebo gel application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TACE-HAIC Plus Lenvatinib for Patients With Unresectable HCC: an Open-label, Single-arm, Phase 2 Trial
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma|Transarterial Chemoembolization
Interventions: PROCEDURE: TACE-HAIC plus lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Zylet Safety and Efficacy Study
Status: COMPLETED
Conditions: Chalazion|Hordeolum
Interventions: DRUG: loteprednol etabonate/tobramycin opthalmic suspension|DRUG: vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gut Hormones After Roux-en-Y Gastric Bypass (RYGBP) Plus Gastric Fundus Resection
Status: COMPLETED
Conditions: Morbid Obesity
Interventions: PROCEDURE: Roux-en-Y gastric bypass (LRYGBP)|PROCEDURE: LRYGBP+gastric fundus resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure
Status: RECRUITING
Conditions: Hepatitis B|Virus Diseases|Liver Failure
Interventions: DRUG: Tenofovir Alafenamide|DRUG: Entecavir|DRUG: Tenofovir disoproxil fumarate
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Electroacupuncture for Gastrointestinal Dysmotility After Abdominal Surgery
Status: UNKNOWN
Conditions: Abdominal Surgery
Interventions: DEVICE: Electroacupuncture|DRUG: Conventional drug therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Meal Gesture Dosing in Adults With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: MiniMed™ 780G insulin pump with Klue Health app utilizing meal gesture micro insulin dosing (meal gesture dosing)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Iron Dextran in Treating Iron Deficiency Anemia
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Ferric Carboxymaltose|DRUG: Iron Dextran
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Protecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: Sacubitril / Valsartan Oral Tablet [Entresto]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCI
Status: COMPLETED
Conditions: Non ST Segment Elevation Acute Coronary Syndrome
Interventions: DRUG: ticagrelor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia
Status: NOT_YET_RECRUITING
Conditions: Stress
Interventions: DRUG: Placebo|DRUG: Oxytocin Intranasal Spray 12 International Unit (12IU)|DRUG: Oxytocin Intranasal Spray 24 International Unit (24IU)|PROCEDURE: Functional MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Combination of Taxotere and Oxaliplatin in Squamous Cell Carcinoma of the Head and Neck
Status: TERMINATED
Conditions: Carcinoma of the Head and Neck
Interventions: DRUG: Taxotere|DRUG: Oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lantus and Apidra in Patients With Acute ST Elevation Myocardial Infarction
Status: TERMINATED
Conditions: AMI
Interventions: DRUG: Insulin Glargine (LANTUS)|DRUG: Insulin Glulisine (Apidra)|DRUG: Standard Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth
Status: COMPLETED
Conditions: Sleep|Pregnancy|Stillbirth|Infant, Low Birth Weight|Infant, Small for Gestational Age|Infant, Very Low Birth Weight|Fetal Growth Retardation|Fetal Hypoxia
Interventions: DEVICE: PrenaBelt|DEVICE: Body Position Sensor|DEVICE: sham-PrenaBelt
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose Escalation Study of Continuous Once-daily Oral Treatment With BIBW 2992 in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assess Safety and Efficacy of ELAD (Extracorporeal Liver Assist System) in Subjects With Alcohol-Induced Liver Failure
Status: COMPLETED
Conditions: Acute Alcoholic Hepatitis
Interventions: BIOLOGICAL: ELAD treatment|OTHER: Standard of care (Control)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases
Status: COMPLETED
Conditions: Primary Myelofibrosis (PMF)|Post-Polycythaemia Vera|Essential Thrombocythaemia Myelofibrosis
Interventions: DRUG: AZD1480
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fasting Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Naproxen Sodium & Pseudoephedrine HCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Novel Argon Laser Iridoplasty for Pigment Dispersion Syndrome
Status: UNKNOWN
Conditions: Pigment Dispersion Syndrome|Pigmentary Glaucoma
Interventions: PROCEDURE: Argon Laser Iridoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Levodopa/Carbidopa Infusion With and Without Oral Catechol-O-methyl Transferase (COMT) Inhibitors
Status: COMPLETED
Conditions: Parkinson Disease
Interventions: DRUG: levodopa/carbidopa|DRUG: entacapone|DRUG: tolcapone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung Cancer
Status: COMPLETED
Conditions: Dyspnea|Non-small Cell Lung Cancer|Small Cell Lung Cancer
Interventions: DRUG: lisinopril|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Nitrous Oxide for Lumbar Puncture
Status: UNKNOWN
Conditions: Pain|Anxiety
Interventions: DRUG: Fixed 50:50 mixture of nitrous oxide and oxygen|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC
Status: ACTIVE_NOT_RECRUITING
Conditions: Locally Advanced Lung Non-Small Cell Carcinoma|Metastatic Lung Non-Small Cell Carcinoma|Recurrent Lung Non-Small Cell Carcinoma|Stage III Lung Cancer AJCC v8|Stage IIIA Lung Cancer AJCC v8|Stage IIIB Lung Cancer AJCC v8|Stage IIIC Lung Cancer AJCC v8|Stage IV Lung Cancer AJCC v8|Stage IVA Lung Cancer AJCC v8|Stage IVB Lung Cancer AJCC v8
Interventions: BIOLOGICAL: Bevacizumab|DRUG: Brigatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase I Clinical Study of Oral CP-4126 in Patients With Advanced Solid Tumour
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: CP-4126|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in the Prevention of Hepatocellular Carcinoma in Cirrhosis
Status: UNKNOWN
Conditions: Microbiota|Hepatocellular Carcinoma|Cirrhosis
Interventions: DIETARY_SUPPLEMENT: Probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LOXO-783|DRUG: Cholestyramine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: Recurrent B Acute Lymphoblastic Leukemia|Recurrent B Lymphoblastic Lymphoma|Refractory B Acute Lymphoblastic Leukemia|Refractory B Lymphoblastic Lymphoma
Interventions: DRUG: Asparaginase Erwinia chrysanthemi|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Aspiration and Biopsy|DRUG: Calaspargase Pegol|DRUG: Cyclophosphamide|DRUG: Cytarabine|PROCEDURE: Diagnostic Imaging|BIOLOGICAL: Inotuzumab Ozogamicin|DRUG: Leucovorin Calcium|PROCEDURE: Lumbar Puncture|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of CPX-351(Cytarabine:Daunorubicin) Liposome Injection in Patients With Advanced Hematologic Cancer.
Status: COMPLETED
Conditions: Hematologic Neoplasms
Interventions: DRUG: CPX-351 (Cytarabine:Daunorubicin) Liposome Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).
Status: RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Treatment A : Budesonide, Glycopyrronium, and Formoterol Fumarate|DRUG: Treatment B: Budesonide and Formoterol Fumarate|DRUG: Treatment C : Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Peer-based Mobile-health Intervention to Increase Access & Adherence to Hepatitis C Treatment & HIV Viral Suppression
Status: COMPLETED
Conditions: Hepatitis C|HIV|Risk Reduction Behavior
Interventions: BEHAVIORAL: Peer Mentor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: AIDA2000 - Risk-Adapted Therapy for Patients With Acute Promyelocytic Leukemia
Status: UNKNOWN
Conditions: Leukemia, Promyelocytic, Acute
Interventions: DRUG: all-trans retinoid acid|DRUG: idarubicin|DRUG: mitoxantrone|DRUG: daunorubicin|DRUG: cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Early Prediction of Clinical Response in Patients With Schizophrenia Treated by Paliperidone ER
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Neuropathy in Patients Monitored for Wild-type TTR Cardiac Amyloidosis (Non-mutated)
Status: COMPLETED
Conditions: Wild-type Amyloid Cardiopathy
Interventions: PROCEDURE: electromyogram
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma
Status: NOT_YET_RECRUITING
Conditions: Asthma
Interventions: DRUG: dupilumab|DRUG: Matching Placebo|DRUG: ICS/LABA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Irinotecan in Treating Patients With Metastatic Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: irinotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS)
Status: RECRUITING
Conditions: Ankylosing Spondylitis
Interventions: DRUG: Jaktinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
Status: RECRUITING
Conditions: Postoperative Pain|Symptomatic Irreversible Pulpitis
Interventions: PROCEDURE: Non-corticosteroid injection|DRUG: Corticosteroid injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
Status: COMPLETED
Conditions: Intervertebral Disk Degeneration|Intervertebral Disk Displacement|Ossification of Posterior Longitudinal Ligament
Interventions: DEVICE: Cervios ChronOs|DEVICE: Bonion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Central Temperature Monitoring by Zero-heath-flux a Non-invasive Technic Compared to Two Invasive Technic During Surgery
Status: COMPLETED
Conditions: Major Surgery in Adult Patients
Interventions: DEVICE: Monitoring by arterial catheter and Spot-on|DEVICE: Monitoring by oesophagal probe and Spot-on
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Progressive Relaxation Exercise on Physiological Parameters, Pain, Anxiety in Colorectal Cancer Surgery
Status: COMPLETED
Conditions: Postoperative Pain|Nursing Caries|Anxiety
Interventions: BEHAVIORAL: Progressive Relaxation Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Fructose Restriction on Liver Steatosis
Status: COMPLETED
Conditions: Nonalcoholic Fatty Liver Disease|Glucose Metabolism Disorders|Endothelial Dysfunction
Interventions: DIETARY_SUPPLEMENT: Glucose|DIETARY_SUPPLEMENT: Fructose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Absorption and Antioxidant Effects of Polyphenolics From Acai
Status: COMPLETED
Conditions: Cardiovascular Disease|Metabolic Syndrome|Obesity
Interventions: DIETARY_SUPPLEMENT: Acai polyphenolics|DIETARY_SUPPLEMENT: Sugary Beverage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Imatinib Mesylate in Treating Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumor
Status: UNKNOWN
Conditions: Gastrointestinal Stromal Tumor
Interventions: DRUG: imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.
Status: UNKNOWN
Conditions: Memory Deficits|Aging|Cognitive Impairment|Physical Activity|Mood Change
Interventions: BEHAVIORAL: Therapy by Dance and Movement|BEHAVIORAL: Tai Chi
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Colonoscopy Screening Using a Novel Slim Colonoscope - a Randomized Controlled Trial
Status: COMPLETED
Conditions: Colorectal Cancer|Adenomas
Interventions: DEVICE: Olympus PCF-Y0014-L|DEVICE: Standard colonoscope
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Dose-finding Study of CAELYXTM and RAD001 in Patients With Advanced Solid Tumors
Status: UNKNOWN
Conditions: Advanced Solid Tumors
Interventions: DRUG: RAD 001 in combination with Caelyx
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting Styles and Parent-Offspring Communication on Sexuality Issues
Status: UNKNOWN
Conditions: Delay in Sexual Debut Among Adolescents|Knowledge About Condom Use|Parent-child Communication, Frequency and Quality
Interventions: BEHAVIORAL: Classroom-based component|BEHAVIORAL: STI/HIV prevention education|BEHAVIORAL: Homework assignment component|BEHAVIORAL: Parenting component
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Improving Employment and Reducing Recidivism Among Prison Offenders Via Virtual Interview Training Tool
Status: ACTIVE_NOT_RECRUITING
Conditions: Criminal Behavior
Interventions: BEHAVIORAL: Virtual Reality Job Interview Training|BEHAVIORAL: Services as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of TAK-861 for the Treatment of Narcolepsy Type 1
Status: RECRUITING
Conditions: Narcolepsy Type 1
Interventions: DRUG: TAK-861|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prospective, Post Marketing Surveillance Study On Erbitux® (Cetuximab) in Patients With Locally Advanced or Recurrent and/or Metastatic Squamous Cell Cancer of the Head and Neck in Korea
Status: COMPLETED
Conditions: Head and Neck Cancer
Interventions: DRUG: Cetuximab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison of Double Pad Fiber Optic Device Versus Conventional Phototherapy
Status: UNKNOWN
Conditions: Neonatal Hyperbilirubinemia
Interventions: DEVICE: Phototherapy with double sided fiber optic pads with blue light at irradiance 30 uW/cm2/nm using Bili Cocoon|DEVICE: Phototherapy from above using NeoBlue at irradiance of 30 uW/cm2/nm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Ultrasonography Guided Embryo Transfer
Status: COMPLETED
Conditions: Infertility, Female
Interventions: PROCEDURE: transabdominal ultrasound guided embryo transfer|PROCEDURE: transvaginal ultrasound guided embryo transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: AERAS-402 3 x 10^8 vp|BIOLOGICAL: AERAS-402 3 x 10^9 vp|BIOLOGICAL: AERAS-402 3 x 10^10 vp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION