pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Randomized Clinical Trial to Increase Physical Activity After a a Hypertensive Pregnancy
Status: COMPLETED
Conditions: Hypertension in Pregnancy|Preeclampsia|Gestational Hypertension
Interventions: BEHAVIORAL: Social incentives-based program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TMS-based Assessment of Mental Training Effects on Motor Learning in Healthy Participants
Status: NOT_YET_RECRUITING
Conditions: Motor Learning
Interventions: DEVICE: Transcranial magnetic stimulation|DEVICE: Peripheral Nerve Stimulation|DEVICE: Transcranial direct current stimulation|DEVICE: Paired Associative Stimulation|DEVICE: Wrist|DEVICE: Robotic arm|DEVICE: Cervicomedullar stimulation|OTHER: Physical training|OTHER: Mental training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Granulocyte Colony Stimulating Factor(G-CSF) Therapy for Patients With ACLF
Status: UNKNOWN
Conditions: Acute on Chronic Liver Failure
Interventions: DRUG: Granulocyte Colony Stimulating Factor|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MBCGT and Psycho-physiological Stress Regulation Group for Depression and Psycho-physiological Stress Patient
Status: UNKNOWN
Conditions: Psychophysiologic Disorders|Stress, Psychological|Unipolar Depression
Interventions: BEHAVIORAL: Mindfulness-based cognitive Group therapy|BEHAVIORAL: psycho-physiological stress regulation group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Prospective Clinical Evaluation of the Total Vascular Access (TVA) FLEX-1 Device Protocol Flex-1-002-IR Intervention Reduction (IR)
Status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)
Interventions: DEVICE: Endovasccular AVF (EndoAVF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Islet Peptide Administration in Type 1 Diabetes (MultiPepT1De)
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: MultiPepT1De injection|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablation of Esophageal Inlet Patches in Patients Referred for Bravo pH-Testing
Status: NOT_YET_RECRUITING
Conditions: GERD|Cough|Metaplasia
Interventions: PROCEDURE: Endoscopic ablation of inlet patch
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics and Safety Study of Siremadlin (HDM201) in Participants With Mild, Moderate and Severe Hepatic Impairment
Status: COMPLETED
Conditions: Hepatic Impairment
Interventions: DRUG: Siremadlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Novel Local Infiltration Anesthesia for Radial Artery Cannulation.
Status: ACTIVE_NOT_RECRUITING
Conditions: Efficiency and Safey of Radial Artery Cannulation
Interventions: PROCEDURE: Conventional Line-blocking|PROCEDURE: Bar-blocking|PROCEDURE: V-blocking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Continuous Infusion of Linezolid Versus Intermittent Dosing in the Treatment of Nosocomial Pneumonia
Status: UNKNOWN
Conditions: Pneumonia
Interventions: DRUG: Continuous infusion Linezolid|DRUG: intermittent dosing linezolid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Propolis Extract, Nanovitamin C and Nanovitamin E in Peri-implant Mucositis
Status: COMPLETED
Conditions: Peri-implant Mucositis
Interventions: DEVICE: Gel containing propolis extract, nanovitamin C and nanovitamin E|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effect of SwitChing AtriPla to Eviplera on Neurocognitive and Emotional Functioning
Status: COMPLETED
Conditions: Neurocognitive Decline|HIV Associated Neurocognitive Disorder
Interventions: DRUG: Eviplera
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study
Status: RECRUITING
Conditions: Pancretic Dissease (Benign/Malignancy)|BIle Duct Diseae(Benign/Malignancy)|Ampulla of Vater Disease (Benign/Malignancy)
Interventions: DRUG: Arm I (Placebo),|DRUG: Arm II (ESMESOL)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Induction Preoperative Chemotherapy for Patients With Locally Advanced Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Paclitaxel, Carboplatinum, Doxorubicin, Endoxan, Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nicotine Patch Trial in Syrian Primary Care Settings
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: DRUG: Transdermal Nicotine|DRUG: Placebo nicotine patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Pharmacodynamic Effects of Single-Dose Co-Administration of LX4211 With Januvia® in Type 2 Diabetics
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LX4211|DRUG: Januvia®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of COVID-19 Vaccine as a Booster Vaccination in Population Aged 18 Years and Above
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19
Interventions: BIOLOGICAL: Recombinant SARS-CoV-2 Vaccine (CHO Cell) LYB001|BIOLOGICAL: ZF2001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation
Status: COMPLETED
Conditions: Extracorporeal Circulation; Complications|Extracorporeal Membrane Oxygenation Complication|Right Heart Failure|Right Ventricular Dysfunction|Respiratory Failure|Respiratory Distress Syndrome
Interventions: BEHAVIORAL: Delphi Rounds to generate consensus opinions among Experts
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dexmedetomidine in Children for Magnetic Resonance Imaging (MRI) Sedation
Status: COMPLETED
Conditions: Anesthesia
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract Adenocarcinoma
Status: COMPLETED
Conditions: Biliary Tract Cancer
Interventions: DRUG: refametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)
Status: COMPLETED
Conditions: Depressive Disorder|Depression|Depressive Disorder, Major|Mood Disorders|Mental Disorders
Interventions: DRUG: OPC-34712 + ADT|DRUG: Placebo + ADT|DRUG: Placebo + ADT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Esthetic Evaluation of Onlay Restorations Constructed From Vita Ambria Glass Ceramics
Status: UNKNOWN
Conditions: Dental Caries|Tooth Decay
Interventions: PROCEDURE: VITA AMBRIA|PROCEDURE: IPS e.max press
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Repeated Intraarticular Injections of Hyaluronic Acid in Patients With OA of the Knee
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Hyaluronic acid|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier)
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Bapineuzumab 0.5 mg/kg|DRUG: Placebo Control|DRUG: Bapineuzumab 1.0 m/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effectiveness Research in Veterans With PTSD
Status: COMPLETED
Conditions: Post-Traumatic Stress Disorder
Interventions: BEHAVIORAL: Cognitive Processing Therapy (CPT)|BEHAVIORAL: Prolonged Exposure (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine With Or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Bladder Cancer
Status: SUSPENDED
Conditions: Bladder Cancer
Interventions: DRUG: gemcitabine hydrochloride|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Study of COVID 19 Convalescent Plasma in High Risk Patients With COVID 19 Infection
Status: COMPLETED
Conditions: Coronavirus|COVID-19|Convalescent Plasma
Interventions: DRUG: Convalescent Plasma
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Pulsed Electromagnetic Field and Pulsed Ultrasound in Treating Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteo Arthritis Knee|Ultrasound Therapy; Complications
Interventions: DEVICE: Pulsed Ultrasound|DEVICE: Pulsed Electromagnetic field|OTHER: Traditional exercise program|DEVICE: Sham Pulsed US & Electromagnetic field
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients
Status: RECRUITING
Conditions: Arrythmia|Cardiomyopathies
Interventions: PROCEDURE: Intra-Op Prophylactic VT ablation|OTHER: Conventional Management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Interpersonal Treatment Program to Prevent Depression and Post-Traumatic Stress Disorder in Low-Income Pregnant Women With Partner Abuse
Status: COMPLETED
Conditions: Depression, Postpartum|Depression
Interventions: BEHAVIORAL: The Reach Out for a Safe Environment (ROSE) program|BEHAVIORAL: Enhanced care as usual (ECU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Endoscopic Ultrasound- Guided Hartmann Reversal Procedure
Status: NOT_YET_RECRUITING
Conditions: Colorectal Neoplasms|Diverticular Diseases|Inflammatory Bowel Diseases
Interventions: PROCEDURE: Endoscopic restoration of gastrointestinal continuity after Hartmann procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Periodontal Treatment on Stress and Pregnancy Relationship
Status: COMPLETED
Conditions: Pregnancy Gingivitis
Interventions: OTHER: Non-surgical periodontal treatment|OTHER: Saliva samples|OTHER: GCF samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety And Efficacy Of Celecoxib Versus Sodium Diclofenac In The Treatment Of Acute Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: Diclofenac|DRUG: Celecoxib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thiamine Supplementation in High Risk Cardiac Surgery Patients
Status: COMPLETED
Conditions: Cardiac Surgery
Interventions: DRUG: Thiamine hydrochloride (200mg) dissolved in 100 ml of normal saline|DRUG: Normal saline (100ml)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)
Status: ACTIVE_NOT_RECRUITING
Conditions: 2019 Novel Coronavirus Disease|2019 Novel Coronavirus Infection|2019-nCoV Disease|2019-nCoV Infection|COVID-19 Pandemic|COVID-19 Virus Disease|COVID-19 Virus Infection|Covid19|Coronavirus Disease 2019|SARS-CoV-2 Infection|SARS-CoV-2 Acute Respiratory Disease|COVID-19
Interventions: DRUG: Famotidine|DRUG: Celecoxib|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Treatment Success in Changing From Olanzapine to Long-acting Injectable Risperidone (RISPERDAL® CONSTA™)
Status: COMPLETED
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: risperidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pragmatic, Randomized Optimal Platelet and Plasma Ratios
Status: COMPLETED
Conditions: Trauma
Interventions: BIOLOGICAL: 1:1:1 Blood Transfusion Ratio|BIOLOGICAL: 1:1:2 Blood Transfusion Ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SporTRIA Study: A Multicentre Trial for Excretion Kinetics of Triamcinolone Acetonide Following Sport Related Intra-articular Injections in Knees; Definitions of the Washout Periods
Status: RECRUITING
Conditions: Doping in Sport|Glucocorticoids
Interventions: DRUG: knee intra-articular infiltration with Triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Skin Denervation in Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: PROCEDURE: 3 mm-punch biopsies of the skin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Wound Irrigation With Irrisept on Abscess Healing (Irrisept UF Study)
Status: TERMINATED
Conditions: Abscess
Interventions: DEVICE: Standard of Care (SoC)|DEVICE: Irrisept Delivery System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Obesity, Oral Contraception, and Ovarian Suppression
Status: COMPLETED
Conditions: Ovarian Suppression
Interventions: DRUG: Low dose formulation|DRUG: High dose formulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Determine if 0.6% ISV-403 is Safe and Effective in the Treatment of Bacterial Conjunctivitis.
Status: COMPLETED
Conditions: Acute Bacterial Conjunctivitis
Interventions: DRUG: ISV-403|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mind-body Interventions for Healthy Aging
Status: COMPLETED
Conditions: Aging
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MBSR)|BEHAVIORAL: Lifestyle Education (LifeEd)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer
Status: TERMINATED
Conditions: Breast Neoplasms
Interventions: DRUG: Abemaciclib|DRUG: Standard Adjuvant ET|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Gastrointestinal Cancer
Status: WITHDRAWN
Conditions: Colorectal Cancer|Esophageal Cancer|Gastric Cancer|Pancreatic Cancer
Interventions: OTHER: iodine I 131 monoclonal antibody CC49-deltaCH2
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Digital Versus Conventional Guided Gingivectomy
Status: NOT_YET_RECRUITING
Conditions: Altered Passive Eruption of Teeth
Interventions: PROCEDURE: Fully digital guided gingivectomy procedure|PROCEDURE: Convectional guided gingivectomy procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of General Anesthesia on Microcirculation of Central and Peripheral Soft Tissue: a Comparison of Inhalational and Intravenous Anesthetics
Status: UNKNOWN
Conditions: Microcirculatory Effects of Anesthesia|Inhalation and Intravenous Anesthesia
Interventions: DRUG: Propofol|DRUG: Sevoflurane|PROCEDURE: General anesthesia induction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Postoperative Pain After Orthopedic Surgery: Does it Help to Give Fentanyl Before Start of Remifentanil Based Anesthesia?
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Adaptation of Human Gut Microbiota to Energetic Restriction
Status: COMPLETED
Conditions: Obesity|Metabolic Diseases|Nutrition Disorders|Body Weight
Interventions: OTHER: stools sampling|OTHER: adipose tissue biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Reflux Esophagitis Phase III Study (Initial Treatment)
Status: COMPLETED
Conditions: Reflux Esophagitis
Interventions: DRUG: Esomeprazole|DRUG: Esomeprazole|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exercise Training and Rehabilitation In Cardiac Amyloidosis
Status: ENROLLING_BY_INVITATION
Conditions: Cardiac Amyloidosis
Interventions: OTHER: Exercise training (ET1+ET2)|BEHAVIORAL: Optimal Medical Therapy (No-ET)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Safety & Efficacy of Oral Ciprodiazole Versus Currently Used Ciprofloxacin & Metronidazole
Status: RECRUITING
Conditions: Surgical Site Infections
Interventions: DRUG: Ciprodiazole|DRUG: Ciprofloxacin Tablets & Metronidazole tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improving Everyday Functioning in Adults Aged 70 and Over Using a Multivitamin Supplement
Status: UNKNOWN
Conditions: Aging|Stress
Interventions: DIETARY_SUPPLEMENT: Multivitamin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Lumateperone for the Prevention of Relapse in Patients With Schizophrenia
Status: ACTIVE_NOT_RECRUITING
Conditions: Schizophrenia
Interventions: DRUG: Lumateperone 42 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Adebrelimab in Combination With Apatinib Gemcitabine and Cisplatin in Biliary Tract Malignancies
Status: RECRUITING
Conditions: Biliary Tract Malignancies
Interventions: DRUG: Adebrelimab|DRUG: Apatinib|DRUG: Gemcitabine|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Walking After Repetitive Transcranial Magnetic Stimulation (rTMS) Inhibitory 1Hz in Vascular Hemiplegia
Status: TERMINATED
Conditions: Hemiplegia
Interventions: DEVICE: SHAM - MagproR30 - DGM-512 - 9016E0741 - Tonika elektronics A/S - Active coil|DEVICE: SHAM inactive - MagproR30 - DGM-512 - 9016E0741 - Tonika elektronics A/S - Inactive coil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Gut Hormones as Mediators of Different Weight Loss Responses After Roux-en-Y Gastric Bypass
Status: UNKNOWN
Conditions: Bariatric Surgery (Gastric Bypass)|Severe Obesity
Interventions: OTHER: Meal tests after saline injection|OTHER: Meal tests after octreotide injection|OTHER: Sham feeding
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Evaluating New Strategy in the Functional Assessment of 3-vessel Disease Using SYNTAXII Score in Patients With PCI
Status: COMPLETED
Conditions: Heart Diseases|Cardiovascular Diseases|3 Vessel Coronary Artery Disease
Interventions: DEVICE: Coronary stent|RADIATION: Multi Slice Computed Tomography|DEVICE: instantaneous wave-free ratio|DEVICE: Fractional flow reserve|DEVICE: Intravascular Ultrasound
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SENSORY RE-TRAINING IN PATIENTS WITH CHRONIC NECK PAIN
Status: RECRUITING
Conditions: Neck Pain|Cervical Pain|Neck Muscle Issue|Neck Pain, Posterior|Cervical Pain, Posterior
Interventions: OTHER: Proprioceptive Training Exercise|OTHER: Tactile Acuity Training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Advanced Melanoma With MK-3475 and Peginterferon
Status: COMPLETED
Conditions: Melanoma
Interventions: DRUG: MK-3475|DRUG: Peginterferon alfa-2b
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Non Small Cell Lung Cancer Metastatic|Non-Small Cell Carcinoma of Lung, TNM Stage 4
Interventions: RADIATION: Radiotherapy|DRUG: Pembrolizumab|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer Metastatic|Brain Metastases
Interventions: RADIATION: whole brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Prophylactic Topical Agents in Reducing Radiation-Induced Dermatitis in Patients With Non-inflammatory Breast Cancer
Status: COMPLETED
Conditions: Breast Carcinoma|Pain|Radiation-Induced Dermatitis|Stage 0 Breast Cancer
Interventions: DRUG: Curcumin-based Gel|PROCEDURE: Dermatologic Complications Management|OTHER: Laboratory Biomarker Analysis|OTHER: Placebo|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as Small Cell, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile Cancer
Status: RECRUITING
Conditions: Small Cell Carcinoma of the Bladder|Small Cell Carcinoma of the Urinary Tract|Squamous Cell Carcinoma of the Bladder|Squamous Cell Carcinoma of the Urinary Tract|Primary Adenocarcinoma of the Bladder|Primary Adenocarcinoma of the Urinary Tract|Renal Medullary Carcinoma|Squamous Cell Carcinoma of the Penis
Interventions: DRUG: Sacituzumab govitecan|DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With OA of the Hip Compared to Intra-articular Steroid Injections
Status: UNKNOWN
Conditions: Osteo Arthritis of Hip
Interventions: PROCEDURE: Cooled RFA treatment|DRUG: Steroid Drug
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-administered Hyperinsufflation Chest on the Risk of Low Respiratory Infection in Patients With Multiple Sclerosis With Sputum Capacity Deficit
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: OTHER: Standardized respiratory management program|OTHER: CoughAssist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure
Status: TERMINATED
Conditions: Prematurity|Respiratory Distress Syndrome|Apnea of Prematurity
Interventions: OTHER: continuous positive airway pressure|OTHER: nasal intermittent positive pressure ventilation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DEVICE: Firebird 2 sirolimus-eluting stent|DEVICE: Excel sirolimus-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Behavior-Based Dietary Intervention in Treating Patients With Hormone-Refractory Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: BEHAVIORAL: behavioral dietary intervention|DIETARY_SUPPLEMENT: dietary intervention|PROCEDURE: therapeutic dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unilateral Laparoscopic Adrenalectomy for Resistant Hypertension in Patients With Adrenal Diseases
Status: UNKNOWN
Conditions: Resistant Hypertension|Adrenal Disease
Interventions: PROCEDURE: unilateral laparoscopic adrenalectomy|DRUG: standard medical treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Bioequivalence of 50-mg Tapentadol (CG5503) Dose Administered as Two 50-mg Tablets Relative to One 100-mg Tablet
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: tapentadol (CG5503) ER 100-mg TRF|DRUG: tapentadol (CG5503) ER 50-mg TRF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Periodontal Regeneration With Recombinant Human Platelet Derived Growth Factor (rH-PDGF-BB) and Allograft
Status: RECRUITING
Conditions: Periodontal Diseases
Interventions: COMBINATION_PRODUCT: Allograft and rHPDGF-BB|COMBINATION_PRODUCT: Allograft and Saline solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin degludec|DRUG: Insulin Icodec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Lymphoma, Mantle-Cell
Interventions: DRUG: PEP07
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Change of Critical Patient Managements and Subsequent Influences Under Epidemic of Coronavirus Disease 19 (COVID-19)
Status: COMPLETED
Conditions: Corona Virus Infection|Critical Illness
Interventions: PROCEDURE: Tracheal intubation and cardiopulmonary resuscitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: ABBV-383
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Negative Pressure Wound Therapy After Surgical Removal of Deep-Seated High-Malignant Soft Tissue Sarcomas of the Extremities and Trunk Wall.
Status: RECRUITING
Conditions: Sarcoma|Cancer|Neoplasms, Connective and Soft Tissue
Interventions: DEVICE: Prevena
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cardioprotective and Mental Health Benefits of the MIND Diet Combined With Forest Bathing
Status: ENROLLING_BY_INVITATION
Conditions: Elevated LDL Cholesterol
Interventions: OTHER: Mind diet intervention|OTHER: Mind plus FB intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Muscle Training Effectiveness in the Degree of Dyspnea and Aerobic Capacity in COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Dyspnea
Interventions: OTHER: Physiotherapy|OTHER: Yoga
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Functional Exercises on Pain and Quality of Life in Females With Primary Dysmenorrhea
Status: NOT_YET_RECRUITING
Conditions: Primary Dysmenorrhea
Interventions: OTHER: Lifestyle modification advice|OTHER: Functional exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strategies for Suspected Pulmonary Embolism in Emergency Departments
Status: COMPLETED
Conditions: Quality of Health Care|Pulmonary Embolism
Interventions: PROCEDURE: Computer-Assisted diagnostic Decision Support|PROCEDURE: written diagnostic guidelines|PROCEDURE: electronic therapeutic reminders
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Clopidogrel Versus Cilostazol in Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Clopidogrel tablet|DRUG: Cilostazol 100 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Concurrent Chemotherapy for Elderly Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: RADIATION: Radiotherapy alone|RADIATION: Concurrent chemoradiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determine the Main Muscle Participant in the Deformation of the Elbow in Hemiplegic Patients
Status: COMPLETED
Conditions: Hemiplegia
Interventions: PROCEDURE: upper limb muscle block|DRUG: 4cc of lidocaïne®
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Tolerability of the Combination of Valproic Acid and Lenalidomide in the Treatment of Patients With Myelodysplastic Syndrome
Status: TERMINATED
Conditions: Myelodysplastic Syndrome MDS
Interventions: DRUG: Valproic aicd|DRUG: Lenalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Training in Parkinson Study
Status: UNKNOWN
Conditions: Parkinson Disease|Impaired Cognition|Alteration in Cognition
Interventions: BEHAVIORAL: Online cognitive training 1|BEHAVIORAL: Online cognitive training 2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Doxycycline Treatment in MEM Patients
Status: RECRUITING
Conditions: Erythema Chronicum Migrans
Interventions: DRUG: Doxycycline 100 milligram Oral Tablet bid, 7 days|DRUG: Doxycycline 100 milligram Oral Tablet bid, 14 days|DRUG: Controls without a history of lyme disease.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Janagliflozin plus metformin|DRUG: Janagliflozin plus metformin|DEVICE: Placebo plus metformin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IA or PE - What is the Best Treatment Option of Steroid Refractory Neurological Autoimmune Diseases
Status: COMPLETED
Conditions: Neurological Autoimmune Diseases
Interventions: OTHER: Apheresis therapy by Octo Nova Technology (DIAMED, Cologne, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Pharmacokinetics, Safety and Tolerability of Baloxavir Marboxil in Healthy Chinese Participants
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: Baloxavir Marboxil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Durvalumab in Combination With Docetaxel, Cisplatin and 5-FU for Locally Advanced Head and Neck Squamous Cell Carcinoma
Status: UNKNOWN
Conditions: Head and Neck Cancers
Interventions: DRUG: Durvalumab|DRUG: Docetaxel|DRUG: Cisplatin|DRUG: 5 Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intra-arterial Tenecteplase for Noncomplete Reperfusion of Intracranial Occlusions
Status: RECRUITING
Conditions: Ischemic Stroke
Interventions: DRUG: Tenecteplase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
Status: COMPLETED
Conditions: Pain|Monitoring, Intraoperative
Interventions: DEVICE: PDR measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A New Piezoelectric Technique in Third Molar Surgery
Status: RECRUITING
Conditions: Tooth Diseases|Piezoelectric Technique|Tooth, Impacted|Tooth Extraction Status Nos|Tooth Avulsion|Facial Swelling
Interventions: PROCEDURE: Piezoelectric surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness
Status: COMPLETED
Conditions: Rosacea
Interventions: DRUG: Coppertone, BAY1183345
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: MSC in Patients With Xerostomia Post XRT in Head and Neck Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Xerostomia Following Radiotherapy
Interventions: BIOLOGICAL: Autologous bone-marrow derived, interferon gamma stimulated mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Liraglutide Effect in Atrial Fibrillation
Status: ACTIVE_NOT_RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Liraglutide|OTHER: RFM|DRUG: Anti Arrhythmics|PROCEDURE: Afib Catheter Ablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Safety And Tolerability Of PF-06342674 (RN168) In Subjects With Multiple Sclerosis (MS)
Status: TERMINATED
Conditions: Multiple Sclerosis
Interventions: BIOLOGICAL: PF-06342674 0.25 mg/kg|BIOLOGICAL: Placebo|BIOLOGICAL: PF-06342674 1.5 mg/kg|BIOLOGICAL: PF-06342674 6.0 mg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Virtual Reality & D-cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder
Interventions: DRUG: D-Cycloserine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Image-guided, Robotically Delivered Transcranial Magnetic Stimulation Treatment for Combat-Related Post-Traumatic Stress Disorder
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DEVICE: Active repetitive transcranial magnetic stimulation|DEVICE: robotic arm|DEVICE: Sham repetitive transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an Innovative Childhood TB Diagnostic Approach Decentralized to District Hospital and Primary Health Care Levels on Childhood Tuberculosis Case Detection and Management in High Tuberculosis Incidence Countries (TB-Speed Decentralisation Study)
Status: UNKNOWN
Conditions: Tuberculosis in Children
Interventions: OTHER: Decentralization of Childhood TB Diagnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Contribution of Cerebral 18F-DOPA PET-CT Scan in High-grade Recurrent Gliomas
Status: RECRUITING
Conditions: High Grade Glioma
Interventions: DEVICE: Brain PET-CT of 18F-DOPA
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Therapeutic Strategy and the Role of Mesenchymal Stromal Cells for ABO Incompatible Liver Transplantation
Status: UNKNOWN
Conditions: Liver Transplantation
Interventions: BIOLOGICAL: Mesenchymal Stem Cells(MSCs)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Retrospective Study of Reoperation After Primary Augmentation With NATRELLE® INSPIRA® Breast Implants
Status: COMPLETED
Conditions: Breast Implantation
Interventions: DEVICE: Smooth NATRELLE® INSPIRA® TruForrm® 1 Breast Implants|DEVICE: Textured NATRELLE® INSPIRA® TruForm® 1 Breast Implants|DEVICE: Smooth NATRELLE® INSPIRA® TruForrm® 2 Breast Implants|DEVICE: Textured NATRELLE® INSPIRA® TruForm® 1 Breast Implants
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)
Interventions: DRUG: Rabeprazole sodium|DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout
Status: COMPLETED
Conditions: Gout
Interventions: DRUG: SHR4640 dose1|DRUG: SHR4640 dose2|DRUG: Placebo oral tablet|DRUG: Allopurinol 300 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN)
Status: COMPLETED
Conditions: Obesity|Overweight|Metabolism and Nutrition Disorder
Interventions: DRUG: Tirzepatide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MISC-CBO to Improve the Mental Health of OVC in South Africa
Status: RECRUITING
Conditions: Mental Disorder, Child
Interventions: BEHAVIORAL: Mediational Intervention for Sensitizing Caregivers (MISC)|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Elderly Patients With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Olmesartan medoxomil|DRUG: Olmesartan medoxomil/hydrochlorothiazide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation
Status: COMPLETED
Conditions: Cystic Fibrosis
Interventions: DRUG: Ivacaftor|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks
Status: TERMINATED
Conditions: Migraine
Interventions: DRUG: 0.5% bupivicaine and 2% lidocaine|DRUG: Saline placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low Phosphate Diets in Patients With Early Stages of Chronic Kidney Disease
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DRUG: Lanthanum Carbonate|DIETARY_SUPPLEMENT: Low Phosphorus Diet|DIETARY_SUPPLEMENT: Unrestricted Phosphorus Diet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: A Study to Assess the Pharmacokinetics of ASP015K in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy Subjects|Pharmacokinetics of ASP015K
Interventions: DRUG: ASP015K
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Safety & Efficacy Study for the Use of Extracorporeal Shockwaves in the Treatment of Diabetic Foot Ulcers
Status: UNKNOWN
Conditions: Chronic Diabetic Foot Ulcers
Interventions: DEVICE: Extracorporeal Shockwaves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery
Status: WITHDRAWN
Conditions: Stage IA Pancreatic Cancer|Stage IB Pancreatic Cancer|Stage IIA Pancreatic Cancer|Stage IIB Pancreatic Cancer
Interventions: DRUG: metformin hydrochloride|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Gedatolisib|DRUG: Palbociclib|DRUG: Letrozole|DRUG: Fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT