pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Docetaxel and Prednisone With or Without Bevacizumab in Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy
Status: COMPLETED
Conditions: Adenocarcinoma of the Prostate|Hormone-resistant Prostate Cancer|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: DRUG: docetaxel|OTHER: placebo|DRUG: prednisone|BIOLOGICAL: bevacizumab|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Catheter Robotics Amigo for Performing Right-Sided Electrophysiology Mapping Studies
Status: COMPLETED
Conditions: Atrial Flutter|Ventricular Tachycardia
Interventions: DEVICE: Amigo catheter robot
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Dose Tolerance, Pharmacokinetics, and Pharmacodynamics Study of CPX-POM in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: CPX-POM - 30 mg/m^2|DRUG: CPX-POM - 60 mg/m^2|DRUG: CPX-POM - 120 mg/m^2|DRUG: CPX-POM - 240 mg/m^2|DRUG: CPX-POM - 360 mg/m^2|DRUG: CPX-POM - 600 mg/m^2|DRUG: CPX-POM - 900 mg/m^2|DRUG: CPX-POM - 1200 mg/m^2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dendritic Cell DKK1 Vaccine for Monoclonal Gammopathy and Stable or Smoldering Myeloma
Status: WITHDRAWN
Conditions: Monoclonal Gammopathy|Smoldering Myeloma|Myeloma
Interventions: BIOLOGICAL: DKK1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Skin bioMARkers for Atopic Eczema Therapy Evaluation
Status: COMPLETED
Conditions: Atopic Eczema/Dermatitis (Non-Specific)
Interventions: DRUG: crisaborole (2%) ointment|DRUG: betamethasone valerate 0.1% cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lexiscan(TM) Rb-82 Myocardial Perfusion PET: A Comparison With Dipyridamole Stress
Status: UNKNOWN
Conditions: Coronary Artery Disease
Interventions: DRUG: Rest/Dipyridamole Stress Rb-82 Myocardial Perfusion PET/CT|DRUG: Rest/Lexiscan(TM) Stress Rb-82 Myocardial Perfusion PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Applications of Dual Energy CT in Patients With Osseous Metastases From Castrate-resistant Prostate Cancer
Status: TERMINATED
Conditions: Dual Energy CT (DECT)|Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Dual Energy Computed Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: EGF816 and Trametinib in Patients With Non-small Cell Lung Cancer Harboring Activating EGFR Mutations
Status: COMPLETED
Conditions: Bronchial Neoplasms
Interventions: DRUG: EGF816|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery
Status: COMPLETED
Conditions: ATIII Deficiency
Interventions: DRUG: Anti-thrombin III|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
Status: UNKNOWN
Conditions: Heart Failure
Interventions: DRUG: Conivaptan|DRUG: Furosemide|DRUG: Conivaptan and furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: Rolfing / Myofascial Structural Integration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor Cells and Treatment De-escalation After Neoadjuvant Therapy for HER2 Positive Breast Cancer
Status: RECRUITING
Conditions: Breast Neoplasms|HER2-positive Breast Cancer|Circulating Tumor Cell
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|OTHER: Circulating tumor cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Vitamin D Dose-Response Study to Establish Dietary Requirements in Infants
Status: COMPLETED
Conditions: Vitamin D Deficiency
Interventions: DRUG: Vitamin D|DRUG: Vitamin D|DRUG: Vitamin D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Thoracic Kyphosis and Osteoporosis: Study of Their Relationship With Respiratory Functions in Chronic Obstructive Pulmonary Disease.
Status: WITHDRAWN
Conditions: COPD|Osteoporosis|Kyphosis
Interventions: PROCEDURE: The high-resolution peripheral scanner (HRpQCT) of the tibia and radius|PROCEDURE: a low-dose imaging system exploration of their thoraco-lumbar spine (EOS system)|OTHER: Questionnaires|OTHER: A search for sarcopenia by studying the strength of the grip (dynamometer)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: lncRNAs as a Biomarker to Assess the Therapeutic Impact of Oral Absorbent ± Probiotics in CKD Patients With PAD
Status: RECRUITING
Conditions: CKD|PAD
Interventions: DIETARY_SUPPLEMENT: Active bamboo charcoal± probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate Usability of Subcutaneous Auto-injector of CT-P17 in Patients With Active Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: BIOLOGICAL: CT-P17 SC AI (adalimumab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Voice-Activated Technology to Improve Mobility & Reduce Health Disparities (EngAGE)
Status: RECRUITING
Conditions: Frailty
Interventions: BEHAVIORAL: Enhanced Engagement|BEHAVIORAL: Standard Engagement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Different PEEP Levels and Tidal Volumes on Regional Lung Function
Status: UNKNOWN
Conditions: Pulmonary Ventilation; Newborn, Abnormal
Interventions: PROCEDURE: Constant PEEP - low tidal volume|PROCEDURE: Constant PEEP - high tidal volume|PROCEDURE: constant tidal volume - low PEEP|PROCEDURE: constant tidal volume - high PEEP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Pharmacokinetics of Sustained-release Depot Tacrolimus: A First-in-human Study
Status: COMPLETED
Conditions: Organ Transplant Rejection|Psoriasis
Interventions: DRUG: Sustained Release Injectable Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of ProEnkephalin to Detect Acute Kidney Injury (AKI)
Status: COMPLETED
Conditions: Heart Failure|Volume Overload|Decompensated Heart Failure|Systolic Heart Failure
Interventions: PROCEDURE: Blood Collection|PROCEDURE: Blood Volume Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multimodality Treatment in Stage III Non-small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Non-small Cell Lung Cancer|NSCLC
Interventions: DRUG: Durvalumab|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nonavalent Prophylactic HPV Vaccine (GARDASIL9) After Local Conservative The NOVEL Trial
Status: UNKNOWN
Conditions: Neoplasia
Interventions: BIOLOGICAL: Gardasill 9™ vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Midline Lumbar Fusion Versus Posterior Lumbar Interbody Fusion
Status: UNKNOWN
Conditions: Degenerative Lumbar Spondylolisthesis
Interventions: PROCEDURE: minimally invasive MID-line Lumbar Fusion (MIDLF)|PROCEDURE: Posterior lumbar interbody fusion (PLIF)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Transplantation for Stiff Person Syndrome (SPS)
Status: TERMINATED
Conditions: Stiff-Person Syndrome
Interventions: BIOLOGICAL: Autologous Hematopoietic Stem Cells|DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: rATG|DRUG: Methylprednisolone|DRUG: G-CSF|DRUG: Rituxan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Donor-Derived EBV-Specific T Cells for Life Threatening EBV-lymphoma (OLIP-EBV-TCL-01-HMR01)
Status: RECRUITING
Conditions: EBV Associated Lymphoma
Interventions: BIOLOGICAL: EBV-specific T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of Intranasal Remimazolam Pharmacokinetics, Pharmacodynamics, Safety and Bioavailability
Status: COMPLETED
Conditions: Procedural Sedation
Interventions: DRUG: Remimazolam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Luspatercept for the Treatment of Anemia in Patients With Myelodysplastic Syndrome (MDS) (MK-6143-001)
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Luspatercept
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Intraocular Pressure (IOP) Reduction in Newly Diagnosed Patients With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Status: COMPLETED
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: OTHER: Standard of Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate the Effects of LCI699 on Cortisol in Participants With Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: LCI699-matching placebo|DRUG: LCI699
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Circular Muscle Exercise (Paula Method) Versus Kegel Exercise for Urinary Stress Incontinence
Status: COMPLETED
Conditions: Urinary Stress Incontinence (SI)
Interventions: BEHAVIORAL: circular muscle exercises versus pelvic floor exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Effects of Acupuncture-assisted Rehabilitation Protocol for Achilles Tendon Rupture
Status: NOT_YET_RECRUITING
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: Traditional rehabilitation protocol|PROCEDURE: Acupuncture-assisted Rehabilitation Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Efficacy of L-Ornithine L-Aspartate Infusion in Patients With Acute Liver Failure
Status: UNKNOWN
Conditions: Acute Liver Failure
Interventions: DRUG: L-Ornithine L-Aspartate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: A Real-world Study of Imraldi® Use
Status: COMPLETED
Conditions: Arthritis, Rheumatoid (RA)|Axial Spondyloarthritis (axSpA)|Arthritis, Psoriatic (PsA)|Crohn's Disease (CD)|Colitis, Ulcerative (UC)
Interventions: DRUG: Adalimumab
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy
Status: TERMINATED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Capmatinib|DRUG: Osimertinib|DRUG: Pemetrexed|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Determining the Ergogenic Effects of Carb10™ Supplementation on Carbohydrate-Rich and Carbohydrate-Restricted Diets
Status: COMPLETED
Conditions: Ketogenic Dieting
Interventions: DIETARY_SUPPLEMENT: Carbohydrate Supplement (Carb10)|OTHER: Diet|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: GORE EXCLUDER® Endoprosthesis - Low Permeability in Treatment of Abdominal Aortic Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysm, Abdominal
Interventions: DEVICE: GORE EXCLUDER® Bifurcated Endoprosthesis-Low Permeability
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium
Status: WITHDRAWN
Conditions: Covid19|Hyperactive Delirium|Pneumonia, Viral
Interventions: DRUG: Valproate|DRUG: Quetiapine|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inotuzumab Ozogamicin and Blinatumomab in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative|Recurrent B Acute Lymphoblastic Leukemia|Refractory B Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: Blinatumomab|BIOLOGICAL: Inotuzumab Ozogamicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CYP2C9 Activity Evaluated With a Simple Finger Prick
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: flurbiprofen|DRUG: flurbiprofen, rifampicin|DRUG: flurbiprofen + fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neoadjuvant Therapy With Docetaxel and Ketoconazole in Patients With High-Risk Prostate Cancer: A Pilot Study
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel|DRUG: Ketoconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients
Status: COMPLETED
Conditions: Atrial Fibrillation|Obesity|Sleep Apnea
Interventions: PROCEDURE: Intervention group|PROCEDURE: control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Study of Chronic Low Back Pain in Patients Taking Pain Medication
Status: COMPLETED
Conditions: Low Back Pain
Interventions: DRUG: duloxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of a 1060 nm Diode Laser, PEMF and Vacuum Assisted MP RF for Non-invasive Fat Reduction
Status: COMPLETED
Conditions: Adipose Tissue Atrophy
Interventions: DEVICE: Venus Bliss
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scleroderma: Functional Disability Between the Dominant and Contralateral Hand.
Status: COMPLETED
Conditions: Scleroderma, Systemic
Interventions: DIAGNOSTIC_TEST: Measurement of joint amplitudes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine Versus ESP - After Bariatric Surgery
Status: RECRUITING
Conditions: Anesthetics|Local Anesthetics
Interventions: DRUG: Ropivacaine injection|DRUG: Lidocaine IV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions
Status: ACTIVE_NOT_RECRUITING
Conditions: Myeloproliferative Disorders|Myelofibrosis|Primary Myelofibrosis|Post-Polycythemia Vera Myelofibrosis|Anemia
Interventions: DRUG: ACE-536|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Catastrophizing and Virtual Reality's Impact on Pain in Patients With Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia|Pain
Interventions: OTHER: Cold Pressor Test|OTHER: Cold Pressor Test + Virtual Reality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: NACER II: Reducing Prenatal Exposures to Household Air Pollution in Rural Guatemala Through a Gas Stove/Behavior Intervention to Improve Neonatal Health
Status: COMPLETED
Conditions: Premature Birth|Fetal Growth Retardation|Infections, Respiratory|Exposure to Environmental Pollution, Non-occupational|Infant, Small for Gestational Age
Interventions: OTHER: Low-cost gas stove|BEHAVIORAL: Peer education classes|BEHAVIORAL: Resource-intensive behavioral intervention approach
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Normalized Glucose Levels in Type 2 Diabetes With Carbohydrate or Caloric Restriction
Status: RECRUITING
Conditions: Diabetes Mellitus Type 2 in Obese
Interventions: OTHER: Low carb diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Effect of Clinical Procedures on Drug Delivery of Mylan Fentanyl Transdermal System 25 µg/hr and Duragesic® 25 µg/hr
Status: TERMINATED
Conditions: Healthy
Interventions: DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 1|DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 2|DRUG: Mylan Fentanyl Transdermal System 25 mcg/h + Clinical Procedure 3|DRUG: Duragesic 25 mcg/h + Clinical Procedure 1|DRUG: Duragesic 25 mcg/h + Clinical Procedure 2|DRUG: Duragesic 25 mcg/h + Clinical Procedure 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Active Ageing and Health
Status: COMPLETED
Conditions: Aging|Chronic Disease|Cognitive Decline|Quality of Life|Physical Activity
Interventions: OTHER: Mild-to-moderate physical activity|OTHER: Cultural group program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: ADAPT: Efficacy of a Dietary Supplement During and After Exercise
Status: COMPLETED
Conditions: Dietary Supplementation During Exercise
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Status: COMPLETED
Conditions: Spinal Cord Injury|Acute Spinal Cord Injury|Bone Loss|Osteoporosis
Interventions: DRUG: Zoledronic acid|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Solution Focused Coaching Strategy Within a Paediatric Multidisciplinary Neuromuscular Clinic
Status: UNKNOWN
Conditions: Neuromuscular Diseases
Interventions: BEHAVIORAL: Solution Focused Coaching|BEHAVIORAL: Intensive Solution Focused Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: To Find the Best Dose of pVGI.1(VEGF2) to Benefit Angina Patients When Given With an Experimental Injection Catheter
Status: UNKNOWN
Conditions: Angina Pectoris
Interventions: GENETIC: pVGI.1(VEGF2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutation Cholangiocarcinoma
Status: RECRUITING
Conditions: Cholangiocarcinoma
Interventions: DRUG: GNS561 + Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of a Tear-based Screening Assay for Breast Cancer
Status: ENROLLING_BY_INVITATION
Conditions: Healthy|Breast Cancer|Breast Cancer Female|Health Care Utilization|Health Knowledge, Attitudes, Practice|Health Personnel Attitude|Health Care Acceptability
Interventions: OTHER: Schirmer Strip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy of Expressive Writing in Mothers of Preterm Infants
Status: UNKNOWN
Conditions: Premature Infant|Mothers
Interventions: BEHAVIORAL: Expressive writing|OTHER: Only Writing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: ISIS 2302-CS22, A 6-Week, Active-Controlled Clinical Study to Evaluate the Effectiveness of Alicaforsen (ISIS 2302) in Patients With Mild to Moderate Active Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: DRUG: Alicaforsen
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Exophthalmometry With 3D Face Scanners
Status: UNKNOWN
Conditions: Exophthalmos|Graves Ophthalmopathy|Orbital Tumor|Orbital Fractures
Interventions: DEVICE: Exophthalmos measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.
Status: UNKNOWN
Conditions: Non Suicidal Self Injury
Interventions: DRUG: Ketamine|DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Determination of the Safety and Effectiveness of an Oral Rinse in the Reduction of Medication Associated Metallic Taste
Status: COMPLETED
Conditions: Medication Associated Metallic Taste , Dysgeusia
Interventions: DEVICE: Metaqil™ Oral Rinse|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Open-Label Study of Golodirsen in Non-Ambulant Patients With Duchenne Muscular Dystrophy
Status: TERMINATED
Conditions: Duchenne Muscular Dystrophy
Interventions: DRUG: Golodirsen 50 MG/1 ML Intravenous Solution [VYONDYS 53]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Gualou Xiebai Banxia Decoction With Danshen Decoction in Treating Unstable Angina.
Status: UNKNOWN
Conditions: Unstable Angina
Interventions: DRUG: Anti-Platelet Drugs|DRUG: Lipid Regulating Drugs|DRUG: Coronary Vasodilator|DRUG: Gualou Xiebai Banxia Decoction & Danshen Decoction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Clinical Application of Chimeric Antigen Receptor T Cells in the Treatment of CD19 Positive Recurrent Refractory B Cell-derived Hematological Malignancies
Status: UNKNOWN
Conditions: B Acute Lymphoblastic Leukemia|Mantle Cell Lymphoma|Follicular Lymphoma
Interventions: DRUG: CD19-CART
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Colonic Propionate, Appetite, and Weight Loss
Status: COMPLETED
Conditions: Healthy Obesity, Metabolically|Appetite Regulation
Interventions: DIETARY_SUPPLEMENT: Inulin-Propionate Esters|DIETARY_SUPPLEMENT: Inulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Group Learning Achieves Decreased Incidents of Lower Urinary Symptoms
Status: COMPLETED
Conditions: Urinary Incontinence, Stress|Urinary Incontinence, Urge
Interventions: BEHAVIORAL: Group Behavioral Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1b/2 Study of Oprozomib in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma
Status: WITHDRAWN
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Oprozomib|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy for Patients With Brain Cancer
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: BIOLOGICAL: filgrastim|DRUG: paclitaxel|DRUG: topotecan hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Metal and Plastic Stents for Preoperative Biliary Decompression
Status: COMPLETED
Conditions: Obstructive Jaundice|Pancreatic Cancer
Interventions: PROCEDURE: Metal stent|PROCEDURE: Plastic stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physiological and Clinical Changes in NHF Therapy
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Hypercapnia|Interstitital Lung Disease
Interventions: DEVICE: Nasal Highflow (NHF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of PrimaVie and Exercise Training on Human Skeletal Muscle (PrimaVie)
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: PrimaVie|OTHER: Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: UROtainer for Bladder Catheter Maintenance, Infection Prevention and Quality of Life
Status: ENROLLING_BY_INVITATION
Conditions: Catheter Blockage
Interventions: DEVICE: UroTainer®|DEVICE: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase I Study of IPI-504 and Docetaxel in Patients With Advanced Solid Tumors
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: IPI-504, docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Precision Medicine Approaches to Renal Osteodystrophy
Status: RECRUITING
Conditions: Renal Osteodystrophy|Chronic Kidney Diseases|CKD-MBD|Bone Turnover Rate Disorder|Secondary Hyperparathyroidism
Interventions: PROCEDURE: miRNAseq analysis|DRUG: Standard treatment for bone disorder
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Intelligent Needle Tip Tracking Using Ultrasound Imaging for Infraclavicular Brachial Plexus Blocks
Status: COMPLETED
Conditions: Nerve Block
Interventions: PROCEDURE: Infraclavicular brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Participants With Focal Onset Seizures With or Without Focal to Bilateral Tonic-clonic Seizures
Status: ACTIVE_NOT_RECRUITING
Conditions: Epilepsy
Interventions: DRUG: Perampanel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Root-canal Medicaments on Post-operative Pain in Re-treatment Cases
Status: COMPLETED
Conditions: Endodontically Treated Teeth
Interventions: OTHER: root canal medicament-calcium hydroxide|OTHER: root canal medicament-chlorhexidine gel|OTHER: root canal medicament-calcuim hyroxide &chlorhexidine ge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Medroxyprogesterone Compared With Venlafaxine in Treating Hot Flashes in Women
Status: COMPLETED
Conditions: Hot Flashes
Interventions: DRUG: medroxyprogesterone|DRUG: venlafaxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effectiveness of P02 Digital Hearing Aids
Status: UNKNOWN
Conditions: Hearing Loss, Bilateral|Sensorineural Hearing Loss
Interventions: PROCEDURE: Hearing Aids Evaluation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Cadonilimab Plus Anlotinib for R/M/P Cervical Cancer
Status: RECRUITING
Conditions: Cervical Cancer
Interventions: DRUG: Cadonilimab|DRUG: Anlotinib|DRUG: Granulocyte-Macrophage Colony-Stimulating Factor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Potential of Camostat in COVID-19
Status: TERMINATED
Conditions: Covid19
Interventions: DRUG: Camostat|DRUG: Placebo|DRUG: Camostat|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Relationship Between Neuromuscular Fatigue, Perceived Tiredness and Level Of Physical Activity of Patients Living With HIV
Status: COMPLETED
Conditions: HIV Seropositivity
Interventions: OTHER: Neuromuscular tests
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Integrated Outpatient Treatment of Opioid Use Disorder and Severe Injection Related Infections
Status: RECRUITING
Conditions: Drug Use|Opioid-use Disorder
Interventions: DRUG: Buprenorphine and Outpatient Parenteral Antibiotic Therapy|DRUG: Buprenorphine and standard of care antibiotic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Creating A Cardiorenal Multidisciplinary Team for Management HF and CKD Patients
Status: COMPLETED
Conditions: Heart Failure|Chronic Kidney Diseases
Interventions: BEHAVIORAL: Multidisciplinary Care Coordination Team
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Study of TJ011133 in Participants With Relapsed/Refractory Advanced Solid Tumors and Lymphoma
Status: COMPLETED
Conditions: Solid Tumor|Lymphoma
Interventions: DRUG: TJ011133|DRUG: Pembrolizumab|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Compare the Efficacy and the Safety of Taxotere and Nanoxel M as Neoadjuvant Chemotherapy in Breast Cancer
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Nanoxel M|DRUG: Taxotere|DRUG: Doxorubicin|DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of MK0140 in Diabetic Patients With Macular Edema (0140-001)
Status: TERMINATED
Conditions: Macular Edema
Interventions: DRUG: triamcinolone acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests.
Status: NOT_YET_RECRUITING
Conditions: Metastatic Breast Cancer|HER2-positive Breast Cancer
Interventions: DRUG: Discontinuation of the anti-HER2 maintenance therapy|DEVICE: Monitoring with signatera test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A
Status: NOT_YET_RECRUITING
Conditions: Hemophilia A
Interventions: DRUG: Gene therapy|OTHER: Biological
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Brentuximab Vedotin in Chinese Participants With Relapsed/Refractory CD30-Positive Hodgkin Lymphoma (HL) or Systemic Anaplastic Large Cell Lymphoma (sALCL)
Status: COMPLETED
Conditions: Hodgkin Disease|Lymphoma, Large-Cell, Anaplastic
Interventions: DRUG: Brentuximab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Your Path to Transplant: A Randomized Control Trial of A Tailored Computer Education Intervention for Living Donor Kidney Transplant
Status: COMPLETED
Conditions: End Stage Renal Disease
Interventions: BEHAVIORAL: Expert System Coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficiency and Safety of Holmium Laser With Moses Technology Versus SuperPulsed Laser System With Thulium Fiber Laser on Renal Stones
Status: ENROLLING_BY_INVITATION
Conditions: Renal Stone
Interventions: DEVICE: Holmium laser with pulse modulation|DEVICE: Thulium fiber laser
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of aPDT on Deep Caries in Permanent Tooth
Status: RECRUITING
Conditions: Dental Caries
Interventions: PROCEDURE: Local anesthesia and rubber dam isolation|PROCEDURE: Incomplete caries removal and microbiological samples collection|PROCEDURE: Dentin washed with sodium 0.9% saline|PROCEDURE: Antimicrobial Photodynamic Therapy|PROCEDURE: Microbiological samples collection and Indirect pulp treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compliance to Vaginal Dilation Therapy in Patients Who Have Undergone Radiation Therapy For Stage IB, Stage IIA, Stage IIB, Stage IIIA, or Stage IIIB Cervical Cancer or Stage IA, Stage IB, Stage IIA, or Stage IIB Endometrial Cancer
Status: COMPLETED
Conditions: Cervical Cancer|Endometrial Cancer|Radiation Toxicity|Sexuality and Reproductive Issues
Interventions: BEHAVIORAL: compliance monitoring|OTHER: questionnaire administration|PROCEDURE: assessment of therapy complications|PROCEDURE: management of therapy complications|PROCEDURE: psychosocial assessment and care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp
Status: NOT_YET_RECRUITING
Conditions: Necrotic Pulp|Post Operative Pain
Interventions: OTHER: Vachellia Nelotica|OTHER: sodium hypochlorite
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of ARDS With Instilled T3
Status: RECRUITING
Conditions: ARDS, Human|Lung, Wet|Thyroid|Pulmonary Edema|Lung Inflammation
Interventions: DRUG: Liothyronine Sodium (T3+0.9% sodium chloride) modified formulation specifically for airway instillation.|OTHER: Non-intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Crizotinib in Pretreated Metastatic Non-small-cell Lung Cancer With MET Amplification or ROS1 Translocation (METROS)
Status: UNKNOWN
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Crizotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Is Barium Enema an Adequate Diagnostic Test for Patients With Positive FOBT?
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: Double-contrast Barium enema, colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Exercise Plus Epoetin Alfa in Treating Cancer Patients Who Have Anemia-Related Fatigue
Status: COMPLETED
Conditions: Anemia|Fatigue|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: BIOLOGICAL: epoetin alfa|PROCEDURE: physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Functional Links Between the Temporomandibular Joint and the Pelvis in Gynecology
Status: RECRUITING
Conditions: Prolapse; Female|Endometriosis-related Pain
Interventions: OTHER: Visceral therapy|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Measurement of Gastric Secretion by MRI Under Inhibition by ProtonPump Inhibitors in Healthy Subjects & in GERD Patients
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease|Healthy Volunteers
Interventions: PROCEDURE: MRI, non invasive 13C-breath test, 24h-intragastric / esophageal pH monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can the Prophylactic Administration of Tranexamic Acid Reduce Blood Loss After Robotic-assisted Radical Prostatectomy?
Status: COMPLETED
Conditions: Robotic-assisted Radical Prostatectomy
Interventions: DRUG: Tranexamic Acid Injectable Product|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Explanations for Negative Laparoscopic Appendectomies and Normal Laparoscopies
Status: COMPLETED
Conditions: Appendicitis|Yersinia Enterocolitica Infection|Yersinia Pseudotuberculosis Infections|Appendectomy
Interventions: PROCEDURE: Diagnostic laparoscopy without appendectomy|PROCEDURE: Diagnostic laparoscopy with appendectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Role of Prophylactic Antibiotics in New Introducer PEG-Gastropexy
Status: COMPLETED
Conditions: Head and Neck Neoplasms|Wound Infection
Interventions: PROCEDURE: PEG-Gastropexy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Recovery Enhancement From Traumatic Brain Injury Using Acceptance and Commitment Therapy - a Pilot Study.
Status: COMPLETED
Conditions: Brain Injuries, Traumatic
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multi-site Study for Evaluation of Clinical Ranges of Whole Blood Clotting Times of Patients on Anticoagulants and Verification of Measurement Precision of Liquid Quality Controls With the Perosphere Technologies' PoC Coagulometer
Status: RECRUITING
Conditions: Coagulation
Interventions: DEVICE: coagulation measurements
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Perioperative Dexmedetomidine on Postoperative Delirium in Patients With Brain Tumors
Status: NOT_YET_RECRUITING
Conditions: Postoperative Delirium
Interventions: DRUG: Dexmedetomidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
Status: RECRUITING
Conditions: Bone Metastases|Bone Neoplasm|Bone Lesion|Bone Cancer|Pain|Cancer Induced Bone Pain|Quality of Life|Tumor|Neoplasm Metastasis
Interventions: RADIATION: External beam radiotherapy|PROCEDURE: MR-HIFU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Carotid and Middle Cerebral Artery Occlusion Surgery Study
Status: COMPLETED
Conditions: Carotid Artery Occlusion|Middle Cerebral Artery Occlusion|Stroke
Interventions: PROCEDURE: bypass surgery|DRUG: Aspirin|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non-Small Cell Lung Carcinoma
Interventions: DRUG: Albumin-bound paclitaxel|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT Comparing Analgesia Post-VATS With Epimorph VS Placebo
Status: TERMINATED
Conditions: Thoracic Surgery, Video-assisted|Postoperative Pain|Rachianesthesia|Sufentanil|Morphine
Interventions: DRUG: Intrathecal Morphine/Sufentanil|DEVICE: PCA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: HepaT1ca: Quantifying Liver Health in Surgical Candidates for Liver Malignancies
Status: COMPLETED
Conditions: Liver Cancer|Surgery|Liver Regeneration|Colorectal Cancer Metastatic
Interventions: DIAGNOSTIC_TEST: Multiparameter magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Serum Galectin-9 Level in Systemic Lupus Erythematosus Patients and it's Association With Disease Activity and Organ Damage
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DIAGNOSTIC_TEST: Serum galectin-9 level
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Dapagliflozin Evaluation in Patients With Inadequately Controlled Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: Dapagliflozin|DRUG: Placebo for dapagliflozin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementation of Genomics in Substance Use Disorder Treatment
Status: COMPLETED
Conditions: Tobacco Use Disorder|Smoking Cessation|Tobacco Use Cessation
Interventions: BEHAVIORAL: Genetically-Informed RiskProfile|OTHER: Brief Cessation Advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Remediation of Schizophrenia in a Community Mental Health Setting
Status: COMPLETED
Conditions: Experimental Condition TCT|Controlled Condition CG
Interventions: OTHER: (TCT) plus evidence-based SE|OTHER: (CG) plus evidence-based SE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Standard Therapy|PROCEDURE: Local Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antibiotics for Children With Severe Diarrhoea
Status: COMPLETED
Conditions: Diarrhea
Interventions: DRUG: Azithromycin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Efficacy and Safety Study of the Tolvaptan Tablets in Patients With Non-hypovolemic Non-acute Hyponatremia
Status: COMPLETED
Conditions: Hypovolemic Hyponatremia
Interventions: DRUG: Tolvaptan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT