pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: U/S Guided SAB VS U/S Guided SAB With Modified Pectoral Nerve Block in Modified Radical Mastectomy
Status: COMPLETED
Conditions: U/S Guided SAB VS U/S Guided SAB Combined With Modified Pectoral Nerve Block
Interventions: PROCEDURE: Serratus Anterior Plane Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Determination of Autonomic Responses to Exposure to Electromagnetic Fields With Low Energy Modulated Frequency
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Breast Cancer
Interventions: DEVICE: Electromagnetic Fields of Low Energy (EEFLE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study of LVGN7409 (CD40 Agonist Antibody) in Locally Advanced, Metastatic or Recurrent/Refractory Malignancy
Status: COMPLETED
Conditions: Cancer
Interventions: BIOLOGICAL: LVGN7409
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Evaluate the Therapeutic Equivalence of Ketoconazole Cream 2% in the Treatment of Tinea Pedis
Status: COMPLETED
Conditions: Tinea Pedis
Interventions: DRUG: Ketoconazole Cream 2%|DRUG: Ketoconazole Cream 2% (G&W Laboratories Inc.)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating Vaccine in Adults With HIV
Status: TERMINATED
Conditions: HIV Infections
Interventions: BIOLOGICAL: HIV-1 gag DNA (formulated with bupivacaine)|BIOLOGICAL: IL-15 DNA (formulated with bupivacaine)|BIOLOGICAL: IL-12 DNA (formulated with bupivacaine)|BIOLOGICAL: Sodium chloride injection USP (0.9%)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Transverse vs Longitudinal Incision in Myomectomy
Status: COMPLETED
Conditions: Myoma;Uterus
Interventions: PROCEDURE: Longitudinal uterine incision|PROCEDURE: Transverse uterine incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD)
Status: UNKNOWN
Conditions: Sickle Cell Disease|HEMOGLOBIN SS|Hemoglobin S Beta-0 Thalassemia|Inflammation|Quality of Life
Interventions: DIETARY_SUPPLEMENT: Omega-3 Fatty Acids: Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA)|OTHER: Placebo Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fish Oil-derived N-3 Polyunsaturated Fatty Acids and Extracellular Vesicles
Status: COMPLETED
Conditions: Extracellular Vesicles; Generation and Function
Interventions: DIETARY_SUPPLEMENT: Fish oil capsules|DIETARY_SUPPLEMENT: High-oleic safflower oil capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Oral Care on Mucositis and Oral Mucosa According to Individual Oral Care Frequency Assessment
Status: COMPLETED
Conditions: Mucositis
Interventions: DRUG: Oral care with a solution containing 0.2% chlorhexidine gluconate a frequency determined according to the results of the Intensive Care Oral Care Frequency Rating Scale.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy & Safety of Orally Administered Valsartan/Amlodipine Combo Therapy vs Amlodipine Monotherapy in Black Patients With Stage II Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: valsartan + amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Two Rescue Therapies for Helicobacter Pylori Infection
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: esomeprazole+amox+levo+tetra|DRUG: esomeprazole+amox+levo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Live Vaccines and Innate Immune Training in COPD.
Status: RECRUITING
Conditions: Trained Innate Immunity|COPD
Interventions: DRUG: BCG vaccine (Danish strain 1331)|DRUG: MMR Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Multicenter Case-control Study to Assess Nailfold Capillary Abnormalities in Systemic Lupus Erythematosus
Status: UNKNOWN
Conditions: Systemic Lupus Erythematosus
Interventions: DEVICE: nailfold capillaroscopy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Limited's Venlafaxine Hydrochloride ER Capsules Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Venlafaxine Hydrochloride Extended-Release Capsules of Torrent Pharmaceuticals Limited
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Drug-Coated Balloon in Anticoagulated and Bleeding Risk Patients Undergoing PCI
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: DEVICE: Percutaneous coronary intervention using drug-coated balloon|DEVICE: Percutaneous coronary intervention using drug-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of Cough Strength in Patients With Tracheostomies
Status: COMPLETED
Conditions: Mechanical Ventilator Weaning
Interventions: OTHER: Tracheostomy cuff inflation.|OTHER: Tracheostomy cuff deflation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Caffeine for Apnea of Prematurity (CAP)
Status: COMPLETED
Conditions: Apnea of Prematurity
Interventions: DRUG: Caffeine citrate injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Status: NOT_YET_RECRUITING
Conditions: Advanced Malignancies With Homologous Recombination Deficiency (HRD) (Breast, Ovarian, mCRPC, Brain Metastases)
Interventions: DRUG: DSB2455
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Open-label Extension Study to Evaluate Subcutaneous Zilucoplan in Pediatric Participants With Generalized Myasthenia Gravis
Status: NOT_YET_RECRUITING
Conditions: Generalized Myasthenia Gravis
Interventions: DRUG: Zilucoplan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PET Imaging Evaluation of [11C]SY08
Status: RECRUITING
Conditions: Parkinson's Disease|Multiple System Atrophy|Dementia With Lewy Bodies|Healthy Controls
Interventions: DRUG: C11-SY08
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: 18F-NaF PET Imaging for Bone Scintigraphy
Status: COMPLETED
Conditions: Bone Metastases From Breast or Prostate Cancer
Interventions: PROCEDURE: NaF PET/CT Imaging|PROCEDURE: 99mTc-medronate whole body bone scan with SPECT|DRUG: 18F-Sodium Fluoride (NaF)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 2 Diabetes Mellitus (T2DM)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: LY900014|BIOLOGICAL: Insulin Lispro
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis (MS)
Interventions: DRUG: elezanumab|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Autologous Fat Grafting Techniques in Patients Undergoing Reconstructive Surgery
Status: COMPLETED
Conditions: Health Status Unknown
Interventions: PROCEDURE: Autologous Fat Graft|PROCEDURE: Autologous Fat Graft|PROCEDURE: Autologous Fat Graft|PROCEDURE: Reconstructive Surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of SHR2554 Alone or in Combination With SHR3680 in the Treatment of mCRPC
Status: TERMINATED
Conditions: Prostate Cancer|Castration-resistant Prostate Cancer
Interventions: DRUG: SHR3680|DRUG: SHR2554
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Examine the Effect of Ulimorelin on the Pharmacokinetics of Midazolam in Healthy Volunteers
Status: COMPLETED
Conditions: Digestive System Disorders
Interventions: DRUG: Midazolam|DRUG: Ulimorelin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Nexus Evaluation Primary Trident II Uncemented Shell
Status: RECRUITING
Conditions: Arthritis of Hip|Hip Dysplasia|Hip Arthropathy|Hip Osteoarthritis
Interventions: DEVICE: Stryker Trident® II HA coated cementless acetabula component
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Satisfaction and Quality of Life Comparison Between Patients Using Cicaplast Baume B5 Versus Dexeryl for the Management of Cutaneous Toxicities Induced by Epidermal Growth Factor Receptor Inhibitors (iEGFR)
Status: COMPLETED
Conditions: Head and Neck Squamous Cell Carcinoma|Colorectal Cancer|Non Small Cell Lung Cancer|Epidermal Growth Factor Receptor Inhibitor
Interventions: OTHER: Cicaplast Balm B5|OTHER: Dexeryl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection
Status: COMPLETED
Conditions: Osteoarthritis|Knee Infection|Prosthetic Joint Infection|Complications; Arthroplasty, Infection or Inflammation|Complications; Arthroplasty
Interventions: PROCEDURE: Static Spacer|PROCEDURE: Articulating Spacer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Status: RECRUITING
Conditions: Coronary Artery Disease|Aortic Valve Stenosis|Extracorporeal Circulation; Complications
Interventions: DEVICE: Minimal Invasive Extracorporeal Circulation|DEVICE: Conventional cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: letetresgene autoleucel (GSK3377794)|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GSK2798745 in Participants With Diabetic Macular Edema
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: GSK2798745
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Combining Medium Cut Off Dialysis Membrane and Diet Modification on Reducing of Inflammation Response
Status: UNKNOWN
Conditions: End Stage Renal Disease|Haemodialysis|Diet, Healthy|Chronic Inflammation
Interventions: DEVICE: medium cut-off (MCO) dialysis membrane|DIETARY_SUPPLEMENT: Dietary fiber mixture (Plantago Psyllium 69% and Inulin 30%)|DIETARY_SUPPLEMENT: Sodium propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Placebo|DRUG: Cimetidine|DRUG: Placebo|DRUG: Placebo|DRUG: BI 1060469 high dose|DRUG: BI 1060469 low dose|DRUG: Naproxen|DRUG: BI 1021958
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Dapagliflozin 10 mg Film-coated Tablets
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Dapagliflozin 10 mg film-coated tablet|DRUG: Forxiga® 10 mg Film-Coated Tablet, manufactured by AstraZeneca Pharmaceuticals LP, USA for AstraZeneca Pharmaceuticals Co. Ltd., China imported by PT AstraZeneca Indonesia, Indonesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: All-trans Retinoic Acid in Combination With a KPD Regimen for the Treatment of Refractory/Relapsed Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma in Relapse|Multiple Myeloma, Refractory
Interventions: DRUG: All-trans Retinoic Acid in combination with the KPD Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma
Interventions: DRUG: doxorubicin hydrochloride|DRUG: ifosfamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Influenza Vaccine, Fluarix/Influsplit Tetra® (2013/2014 Season), in Adults 18 Years of Age and Older
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Fluarix/Influsplit Tetra® (2013-2014 season)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Dasatinib in Treating Patients With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Pancreas|Recurrent Pancreatic Cancer|Stage IV Pancreatic Cancer
Interventions: DRUG: dasatinib|PROCEDURE: laboratory biomarker analysis|PROCEDURE: physiologic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Sr-89 for Differentiated Thyroid Cancer With Bone Metastases
Status: NOT_YET_RECRUITING
Conditions: Thyroid Neoplasm Follicular|Bone Metastases
Interventions: DRUG: Sr-89
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PULSTA Transcatheter Pulmonary Valve Pre-Approval Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Heart Diseases|Pulmonary Valve Regurgitation|Pulmonary Valve Stenosis|Tetralogy of Fallot
Interventions: DEVICE: PULSTA TPV System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effectiveness of Intravitreal Aflibercept in Patients With Diabetic Macular Edema and/or Macular Edema Secondary to Retinal Vein Occlusion, Which Either Have or Have Not Been Pretreated for Their Disease
Status: COMPLETED
Conditions: Macular Edema
Interventions: DRUG: Aflibercept (Eylea, BAY86-5321)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: AB680|DRUG: Etrumadenant|DRUG: Zimberelimab|DRUG: Bevacizumab|DRUG: m-FOLFOX-6 regimen|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke
Status: COMPLETED
Conditions: Stroke, Acute
Interventions: DRUG: Naloxone hydrochloride 5.0mg/5ml|DRUG: Sodium Chloride 45mg/5ml
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of RUTI® With the Standard of Treatment for Tuberculosis
Status: RECRUITING
Conditions: Tuberculosis, Pulmonary
Interventions: BIOLOGICAL: RUTI® Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrafiltration Efficacy of a PD Solution Containing Icodextrin-Xylitol-Carnitine
Status: UNKNOWN
Conditions: End Stage Renal Disease (ESRD)
Interventions: DRUG: Icodextrin, xylitol and carnitine solution for peritoneal dialysis|DRUG: EXTRANEAL 7.5G/100Ml Peritoneal Dialysis Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: YF476 in Barrett's Esophagus
Status: COMPLETED
Conditions: Barrett's Esophagus
Interventions: DRUG: YF476|DRUG: YF476 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Orally Administered JNJ-56136379 to Evaluate Safety, Tolerability and Pharmacokinetics After Single Ascending Doses and One Multiple Dose Regimen in Healthy Participants (Part I), and After Multiple Dose Regimens in Participants With Chronic Hepatitis B (Part II)
Status: COMPLETED
Conditions: Healthy|Hepatitis, Chronic
Interventions: DRUG: JNJ-56136379|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Patient Satisfaction Study of BOTOX® Cosmetic in the Treatment of Moderate to Severe Frown Lines
Status: COMPLETED
Conditions: Glabellar Frown Lines
Interventions: BIOLOGICAL: botulinum toxin Type A|DRUG: normal saline (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Growth Hormone and Exclusion Diet Therapy in Juvenile Crohn's Disease
Status: WITHDRAWN
Conditions: Crohn's Disease
Interventions: DRUG: Growth Hormone|DIETARY_SUPPLEMENT: Nutraceutical Combination|OTHER: Exclusion Diet|OTHER: Placebo Growth Hormone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endostar Plus Toripalimab as Adjuvant Therapy for Resectable Stage III-Oligometastatic Stage IV Cutaneous Melanoma
Status: RECRUITING
Conditions: Clinical Stage III Cutaneous Melanoma AJCC v8|Clinical Stage IV Cutaneous Melanoma AJCC v8
Interventions: DRUG: Endostar|DRUG: Toripalimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Primary Care Based Depression Prevention for Adolescents/Young Adults/Young Adults and Young Adults
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: MI + CATCH-IT Internet Site|BEHAVIORAL: BA (brief advice) + CATCH-IT Internet site
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention
Status: COMPLETED
Conditions: Cocaine-Related Disorders
Interventions: BEHAVIORAL: Acceptance and Commitment Therapy (ACT)|BEHAVIORAL: Drug Counseling (DC)|BEHAVIORAL: Contingency Management (CM)|DRUG: Placebo|DRUG: Modafinil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Pressure After Endovascular Stroke Therapy-II
Status: COMPLETED
Conditions: Acute Stroke|Endovascular Thrombectomy
Interventions: DRUG: Nicardipine|DRUG: Labetalol|DRUG: Hydralazine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ease of Use and Safety of the New U300 Pen Injector in Insulin-Naïve Patients With T2DM
Status: COMPLETED
Conditions: Diabetes Mellitus Type 2
Interventions: DRUG: Insulin glargine U300 (new formulation of insulin glargine) HOE901
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Women With Minor Degrees of Glucose Intolerance and the Postpartum Glucose Tolerance Test
Status: UNKNOWN
Conditions: Glucose Tolerance Impaired in Pregnancy
Interventions: DIAGNOSTIC_TEST: 75g oral glucose tolerance test|DIAGNOSTIC_TEST: 75g GTT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: Using TMS to Understand Neural Processes of Social Motivation
Status: NOT_YET_RECRUITING
Conditions: Social Avoidant Behavior|Major Depressive Disorder|Social Anxiety Disorder
Interventions: DEVICE: TMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mitopure™ (Proprietary Urolithin A) Bioavailability in Healthy Adults
Status: COMPLETED
Conditions: Healthy|Healthy Aging
Interventions: DIETARY_SUPPLEMENT: Mitopure™ (Proprietary Urolithin A)|DIETARY_SUPPLEMENT: Pomegranate Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2
Status: RECRUITING
Conditions: Inhibitory Control|Self Efficacy|Suicide Ideation|Suicide, Attempted|Locus of Control|Process Factors|Movement Synchrony
Interventions: BEHAVIORAL: Attempted Suicide Short Intervention Program (ASSIP)|BEHAVIORAL: Standard of care plus resource interview group (STAR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Gum Chewing on Appetite and Digestion
Status: COMPLETED
Conditions: The Null Hypothesis is That Food Rheology Will Have no Effect on These Indices|The Alternate Hypothesis is That Increased Mechanical Stimulation Will Result in Stronger Satiation/Satiety and Reduced Energy Intake|It is Hypothesized That the Effects of Mastication Will be Less Evident in Obese Compared to Lean Individuals
Interventions: OTHER: soft gum|OTHER: firm gum|OTHER: no gum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chronic Cardiovascular and Gut-bacteria Effects of Phenolic Rich Oats in Adults With Above Average Blood Pressure
Status: UNKNOWN
Conditions: Healthy
Interventions: OTHER: High avenanthramide, phenolic acid|OTHER: Low avenanthramide, medium phenolic acid|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Capecitabine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: A Usability Study of a Smoking Cessation Decision Aid in People With a Recent First Episode of Psychosis
Status: COMPLETED
Conditions: Smoking|Psychosis
Interventions: BEHAVIORAL: Web-based computer program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal
Status: COMPLETED
Conditions: Kidney Transplantation
Interventions: PROCEDURE: Kidney Biopsy|DRUG: Rapamune (sirolimus/rapamycin)|DRUG: Tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Platinum-based Versus Non-platinum-based Neoadjuvant Chemotherapy in Triple-negative Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Triple Negative Breast Cancer
Interventions: DRUG: Doxorubicin|DRUG: Cyclophosphamide|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Effectiveness of Esmirtazapine in Participants With Chronic Primary Insomnia (P05706)
Status: COMPLETED
Conditions: Insomnia
Interventions: DRUG: Esmirtazapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: EHR-embedded OCDT in Breast or GI Cancer
Status: COMPLETED
Conditions: Oral Cancer Directed Therapy|Breast Cancer|Gastrointestinal Cancer|Oral Chemotherapy
Interventions: OTHER: Active Care Team Alert|OTHER: Passive Care Team Alert
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Vitamin D Supplementation and Cardiac Hypertrophy in Chronic Kidney Disease (CKD)
Status: UNKNOWN
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D Cholecalciferol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of RSVpreF Vaccination and RSV Challenge in Healthy Adults
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: RSVPreF|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exploratory, Phase I,Open Label,Non-randomized Study of [F18]CP-18 PET in Normal and Breast Cancer Subjects
Status: TERMINATED
Conditions: Breast Cancer
Interventions: RADIATION: [F18]CP-18 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Asian Phase 2 Study for Treatment of Pain Associated With Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Pain|Diabetic Peripheral Neuropathy
Interventions: DRUG: DS-5565|DRUG: DS-5565|DRUG: DS-5565|DRUG: Placebo|DRUG: Pregabalin capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Azacitidine and Erythropoietin Versus Azacitidine Alone for Patients With Low-Risk Myelodysplastic Syndromes
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Azacitidine|DRUG: Erythropoietin|DRUG: Azacitidine (Monotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD)
Status: COMPLETED
Conditions: Stress Disorders, Post-Traumatic
Interventions: DRUG: Paroxetine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Negative Pressure Therapy Dressing Compared With Hydrogel Dressing.
Status: TERMINATED
Conditions: Wound Infection, Surgical
Interventions: PROCEDURE: Pico®" negative pressure dressing|PROCEDURE: Aquacel Surgical®" hydrogel dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Adaptogen Elixir on Sleep Improvement
Status: RECRUITING
Conditions: Sleep Disorder|Anxiety Disorders
Interventions: DIETARY_SUPPLEMENT: Placebo drink|DIETARY_SUPPLEMENT: Adaptogen Elixir drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?
Status: COMPLETED
Conditions: Irritable Bowel Syndrome|Diarrhea
Interventions: DRUG: Colesevelam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis
Status: COMPLETED
Conditions: Cystic Fibrosis|Exocrine Pancreatic Insufficiency|Pancreatic Diseases|Digestive System Diseases
Interventions: DRUG: Pancrelipase
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Strength At Home: Veterans' Program (PTSD-Focused Therapy for Anger and Relationship Conflict Among OEF/OIF Veterans)
Status: COMPLETED
Conditions: Domestic Violence
Interventions: BEHAVIORAL: PTSD-Focused CBT for Partner Violence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Nordic Berries on Cognitive Function, Cardiometabolic Risk Markers and Gut Microbiota in Adults With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Cognitive Impairment, Mild|Memory Impairment
Interventions: OTHER: Active berry product|OTHER: Reference product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Tolerability, Drug Interactions, and Antiviral Activity of Rilpivirine in Antiretroviral-Naive HIV-Infected Children Less Than 12 Years of Age
Status: WITHDRAWN
Conditions: HIV Infections
Interventions: DRUG: Rilpivirine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Interventions to Improve Resiliency & Burnout in Behavioral Health Residential Staff
Status: ENROLLING_BY_INVITATION
Conditions: Burnout|Stress|Coping Skills|Depression|Anxiety|Physical Inactivity|Sleep|Healthy Eating
Interventions: BEHAVIORAL: Resiliency Training|BEHAVIORAL: Task Sharing|BEHAVIORAL: Workplace Improvement Learning Collaborative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip
Status: UNKNOWN
Conditions: PJI|Bone and Joint Infection|Pharmacokinetics
Interventions: DRUG: sampling blood|DRUG: Sampling synovial fluid|DRUG: Sampling bone tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: High Flow Oxygen Therapy in Patients Undergoing Bronchoscopy Under Sedation
Status: NOT_YET_RECRUITING
Conditions: Respiratory Failure|Hypercapnic Acidosis
Interventions: DEVICE: High Flow Oxygen Therapy (HFOT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Safety and Ability of a Once-a-day Dose of an Orally Inhaled Medicine [ie, Glycopyrrolate Inhalation Solution = GIS] to Improve Airflow in the Lungs When Delivered With an Electronic eFlow Nebulizer System in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Glycopyrrolate Inhalation Solution 25mg|DRUG: Glycopyrrolate Inhalation Solution 75mg|DRUG: Glycopyrrolate Inhalation Solution 200mg|DRUG: Glycopyrrolate Inhalation Solution 200mg Jet|DRUG: Glycopyrrolate Inhalation Solution 500mg|DRUG: Glycopyrrolate Inhalation Solution1000mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Flexible Tip Bougie vs Tube With Stylet for Intubation With a Videolaryngoscopy in ICU (VIDEOL-FLEXTIP)
Status: RECRUITING
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Flexible Tip Bougie|DEVICE: Endotracheal Tube with Stylet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Acupuncture for the Management of Postoperative Pain in Patients With Pancreatic or Colorectal Cancer Undergoing Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Resectable Colorectal Carcinoma|Resectable Digestive System Carcinoma|Resectable Pancreatic Carcinoma
Interventions: PROCEDURE: Acupuncture Therapy|OTHER: Best Practice|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mezigdomide Plus Ixazomib and Dexamethasone for Relapsed and Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Relapsed and Refractory Multiple Myeloma
Interventions: DRUG: Mezigdomide|DRUG: Ixazomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Quadruple Regimens for Helicobacter Pylori Infection in Egypt
Status: COMPLETED
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Hybrid regimen|DRUG: Reverse hybrid regimen|DRUG: Levofloxacin quadruple regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: carboplatin|DRUG: paclitaxel albumin-stabilized nanoparticle formulation|GENETIC: protein expression analysis|OTHER: immunoenzyme technique|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD7594 Administered Once Daily by Inhalation in Asthmatic Subjects
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: AZD7594 DPI 55μg/50μg.|DRUG: AZD7594 DPI 99 µg/90 µg|DRUG: AZD7594 DPI 198 µg/180 µg|DRUG: AZD7594 DPI 396 µg/360 µg once daily.|DRUG: AZD7594 DPI 792 µg/720 µg|DRUG: Placebo for AZD7594 once daily.|DRUG: FF 100 µg once daily (open-label)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Disparities in National Kidney Allocation Policy
Status: COMPLETED
Conditions: Kidney Disorders
Interventions: OTHER: Performance Feedback Reports|OTHER: Educational Video for Staff|OTHER: Educational Video for Patients|OTHER: Educational Webinar|OTHER: Standard Care|OTHER: United Network for Organ Sharing (UNOS) Pamphlet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Lipoprotein Apheresis in Refractory Angina Study
Status: COMPLETED
Conditions: Refractory Angina|Raised Lipoprotein(a)>50mg/dL or >500mg/L
Interventions: OTHER: Lipoprotein Apheresis|OTHER: Sham Apheresis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation
Status: ACTIVE_NOT_RECRUITING
Conditions: Electroencephalography|Refractory Epilepsy|Brain Imaging|Surgery
Interventions: DIAGNOSTIC_TEST: No electrical source imaging (ESI)|DIAGNOSTIC_TEST: Automated electrical source imaging (ESI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lung Cancer Radiotherapy Using Realtime Dynamic Multileaf Collimator (MLC) Adaptation And Radiofrequency Tracking
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms|Lung Neoplasms
Interventions: DEVICE: MLC Tracking
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial
Status: NOT_YET_RECRUITING
Conditions: Oral Submucous Fibrosis
Interventions: DRUG: Metformin Hydrochloride|DRUG: betamethasone dipropionate|DRUG: Pentoxifylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Axillary Nerve Block Combined With Suprascapular Nerve Block
Status: COMPLETED
Conditions: Rotator Cuff Tear
Interventions: PROCEDURE: Group I, SSNB & ANB|PROCEDURE: Group II, SSNB alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Endorphin Massage Application to Women Who Gave Birth Vaginally
Status: COMPLETED
Conditions: Pain|Birth, First
Interventions: OTHER: Endorphin massage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy, Safety And Tolerability Study of Flexibly Dosed Paliperidone Extended Release (ER) in Participants With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Analgesia in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: several drugs: morphine chloride,ropivacaine,epinephrine,ketorolac|DRUG: ropivacaine,morphine chloride,epinephrine,ketorolac|DRUG: ropivacaine|DRUG: morphine ,ketorolac
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Decalcification Bone Scaffold for Cartilage Lesions of the Knee
Status: UNKNOWN
Conditions: Cartilage Injury
Interventions: PROCEDURE: decalcification bone scaffold|PROCEDURE: microfracture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rosuvastatin/Ezetimibe Versus Rosuvastatin in ASCVD Patients With Type 2 DM
Status: COMPLETED
Conditions: Atherosclerotic Cardiovascular Disease|Type 2 Diabetes Mellitus
Interventions: DRUG: Rosuvamibe|DRUG: Monorova
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BEnefit of HYpnosis on Pain During Stitches in Emergency Room
Status: NOT_YET_RECRUITING
Conditions: Wound of Skin
Interventions: OTHER: Hypnosis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Inhaling Carbon Monoxide to Treat Patients With Intestinal Paralysis After Colon Surgery.
Status: TERMINATED
Conditions: Ileus
Interventions: DRUG: Inhaled Carbon Monoxide|DRUG: Synthetic Air
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Iodine I 131 Tositumomab or Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DEVICE: Patient-specific dosimetry|DEVICE: conventional dosimetry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
Status: RECRUITING
Conditions: Cerebral Amyloid Angiopathy
Interventions: DRUG: Placebo|DRUG: ALN-APP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease.
Status: ENROLLING_BY_INVITATION
Conditions: Metabolic Acidosis|CKD|Electrolyte and Fluid Balance Conditions
Interventions: DIETARY_SUPPLEMENT: Dietary supplement consisting of 40 mmol/daily of potassium chloride|DIETARY_SUPPLEMENT: Dietary supplement consisting of 40 mmol/daily of potassium gluconate|DIETARY_SUPPLEMENT: Dietary supplement consisting of 40 mmol/daily of potassium bicarbonate|DIETARY_SUPPLEMENT: Dietary supplement consisting of 40 mmol/daily of sodium chloride|DIETARY_SUPPLEMENT: Dietary supplement consisting of 40 mmol/daily of sodium bicarbonate|DIETARY_SUPPLEMENT: Placebo caps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Magnesium Sulphate Versus Fentanyl Sedation During Burr-hole Surgery
Status: COMPLETED
Conditions: Monitored Anesthesia Care
Interventions: DRUG: Magnesium Sulphate|DRUG: Fentanyl|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Anxiety and Pain Level in Patients Undergoing Obesity Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Anxiety|Pain, Postoperative
Interventions: OTHER: progressive relaxation exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: S0514 Sorafenib in Treating Patients With Unresectable or Metastatic Gallbladder Cancer or Cholangiocarcinoma
Status: COMPLETED
Conditions: Adenocarcinoma of the Extrahepatic Bile Duct|Adenocarcinoma of the Gallbladder|Adenocarcinoma With Squamous Metaplasia of the Gallbladder|Cholangiocarcinoma of the Extrahepatic Bile Duct|Cholangiocarcinoma of the Gallbladder|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Squamous Cell Carcinoma of the Gallbladder|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: sorafenib tosylate|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps
Status: COMPLETED
Conditions: Nasal Polyps|Chronic Rhinosinusitis With Nasal Polyps
Interventions: DRUG: Doxycycline 100 mg Oral Tablet|DRUG: Prednisolone 20 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient-controlled Sedation With Propofol During Cataract Surgery Under Topical Anesthesia
Status: COMPLETED
Conditions: Sedation
Interventions: DRUG: Propofol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Combigan Ophthalmic Solution(Brimonidine 0.2% and Timolol 0.5%)With Latanoprost Compared With Latanoprost Monotherapy
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Combigan Ophthalmic Solutiom
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: ECT
Clinical trial: Parallel Arm Trial of AD109 and AD504 In Patients With OSA
Status: COMPLETED
Conditions: OSA - Obstructive Sleep Apnea
Interventions: DRUG: AD109|DRUG: AD504|DRUG: Atomoxetine Hydrochloride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT