pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Development of a Fever Detection Algorithm Based on Non-invasive Skin-based Sensor Values in Infants up to 18 Months of Age
Status: SUSPENDED
Conditions: Fever
Interventions: OTHER: Unobtrusive data collection using wearable non-invasive sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Topotecan in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian Carcinoma
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Hycamptin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of PET-CT Scanner Performances to Detect Infra-centimetric Lesions in Patients With Cancer
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Patients with a cancer for which a FDG-PET scanner must be performed
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparative Efficacy and Safety Study of GP2015 and Enbrel® in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: GP2015
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Lower-risk MDS Patients With and Without Improvements in Fatigue Following Blood Transfusion Therapy
Status: TERMINATED
Conditions: Myelodysplatic Syndromes
Interventions: OTHER: Physiological tests to measure fatigue level
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rhenium-188-HEDP vs. Radium-223-chloride in Patients With Advanced Prostate Cancer Refractory to Hormonal Therapy
Status: UNKNOWN
Conditions: Prostate Cancer Metastatic to Bone
Interventions: DRUG: Radium-223 chloride|DRUG: Rhenium-188-HEDP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics
Status: RECRUITING
Conditions: Individual Variability in (Poly)Phenol Metabolism
Interventions: OTHER: Coffee|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Idasanutlin, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Loss of Chromosome 17p|Recurrent Plasma Cell Myeloma
Interventions: DRUG: Dexamethasone|DRUG: Idasanutlin|DRUG: Ixazomib Citrate|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ethanol Locks for the Treatment of Central Venous Line Infections
Status: TERMINATED
Conditions: Bloodstream Infection
Interventions: DRUG: 70% ethanol|DRUG: heparin flush solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS)
Status: RECRUITING
Conditions: Severe Fever With Thrombocytopenia Syndrome
Interventions: DRUG: Methylprednisolone|DRUG: intravenous immunoglobulin|DRUG: Tocilizumab|DRUG: Low molecular weight heparin|OTHER: conventional treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigator-Initiated Trial of Combined Ipilimumab, Nivolumab and Stereotactic Radiation in Patients With Metastatic Clear-Cell RCC (ccRCC) Who Have Failed Treatment With Single-Agent Nivolumab
Status: WITHDRAWN
Conditions: Clear Cell Renal Cell Carcinoma|Metastatic Renal Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|RADIATION: Steriotactic radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Drug Levels of Danicamtiv in Healthy Japanese and Caucasian Participants
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Danicamtiv|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Duration of Analgesia After Popliteal Fossa Nerve Blockade: Effects of Dexamethasone and Buprenorphine
Status: COMPLETED
Conditions: Patients Undergoing Ankle Surgery
Interventions: DRUG: A. Control Nerve Block. IV Dexamethasone (4 mg).|DRUG: B. Nerve Block with Dexamethasone (4 mg). IV saline.|DRUG: C. Control Nerve Block. IV Dexamethasone (4 mg). IV Buprenorphine (0.3 mg)|DRUG: D. Nerve Block with Buprenorphine (0.3 mg). IV Dexamethasone (4 mg).|DRUG: E. Nerve Block with Dexamethasone (4 mg) / block Buprenorphine (0.3 mg).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Factors in Learning And Plasticity: Healthy Vision
Status: RECRUITING
Conditions: Central Visual Impairment|Macular Degeneration
Interventions: BEHAVIORAL: Condition 1: Training visual sensitivity|BEHAVIORAL: Condition 2: Training spatial integration|BEHAVIORAL: Condition 3: Training spatial attention|BEHAVIORAL: Condition 4: Combination training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Laparoscopic Tubal Adhesiolysis Versus IVF-ICSI
Status: COMPLETED
Conditions: Tubal Factor Infertility
Interventions: PROCEDURE: Tubal adhesiolysis|DRUG: IVF/ICSI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience Among Surrogate Decision-Makers of ICU Patients
Status: COMPLETED
Conditions: Critical Illness|Communication Disabilities
Interventions: BEHAVIORAL: EMPOWER|OTHER: Enhanced Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pramlintide (Symlin) for the Treatment of Hypoglycemia Following Gastric Bypass Surgery
Status: COMPLETED
Conditions: Hypoglycemia|Evidence of Previous Gastric Surgery
Interventions: DRUG: Pramlintide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis
Status: TERMINATED
Conditions: Relapsing Remitting Multiple Sclerosis|Optic Neuropathy|Optic; Neuritis, With Demyelination
Interventions: DRUG: CNM-Au8|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss
Status: RECRUITING
Conditions: Sensorineural Hearing Loss, Bilateral
Interventions: COMBINATION_PRODUCT: AAVAnc80-hOTOF via Akouos Delivery Device
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids
Status: COMPLETED
Conditions: Inborn Errors of Metabolism
Interventions: DRUG: Oil special 107 and MYGLIOL 810
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants
Status: UNKNOWN
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Poliomyelitis|Haemophilus Influenzae Type b Infection
Interventions: BIOLOGICAL: DTwP-HepB-Sabin IPV-Hib|BIOLOGICAL: Pentavalent vaccine and Salk IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients
Status: COMPLETED
Conditions: Skin Cancer|Non-melanoma Skin Cancer|Sun Damaged Skin|Actinic Keratosis
Interventions: DRUG: Levulan® Kerastick®|DRUG: BLU-U Blue Light Photodynamic Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Implementation and Impact of the Adapted Choose to Move (CTM) Program
Status: ENROLLING_BY_INVITATION
Conditions: Aging|Mobility Limitation|Physical Inactivity|Sedentary Behavior|Loneliness|Social Isolation
Interventions: BEHAVIORAL: Choose to Move
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase II Study of Concurrent Sorafenib and Intensity-modulated Radiotherapy (IMRT) for Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma, Radiotherapy, Sorafenib
Interventions: RADIATION: concurrent sorafenib and IMRT, followed sorafenib maintenance
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Registry of Catheter Intervention in Pulmonary Embolism
Status: RECRUITING
Conditions: Pulmonary Embolism|Pulmonary Embolism Acute Massive|Pulmonary Embolism Acute|Pulmonary Embolism and Thrombosis|Pulmonary Thromboembolisms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of SNB on the QoR in Patients Undergoing Supratentorial Tumor Resection
Status: RECRUITING
Conditions: Postoperative Analgesia|Quality of Recovery|Supratentorial Tumor|Craniotomy|Scalp Nerve Block
Interventions: PROCEDURE: scalp nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Feasibility Study of Delivering Adolescent Nutrition Interventions Through School-Based Platforms in Ethiopia
Status: COMPLETED
Conditions: Dietary Diversity
Interventions: BEHAVIORAL: School Interventions|BEHAVIORAL: Community Interventions|BEHAVIORAL: School System Interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Kinesio Tape Application With EDF Technique on Active Trigger Points of Upper Trapezius Muscle
Status: COMPLETED
Conditions: Myofascial Pain Syndrome|Myofascial Trigger Point Pain
Interventions: DEVICE: Kinesio tape|DEVICE: Sham Kinesio Tape
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Prone Positioning on Vital Parameters in Infants With Acute Bronchiolitis
Status: COMPLETED
Conditions: Respiratory Syncytial Virus (RSV)|Acute Bronchiolitis|Infant, Newborn, Disease|Infant, Premature, Diseases
Interventions: OTHER: Prone position/ Abdominal position
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1/2 Study of Motolimod, Doxorubicin, and Durvalumab in Recurrent, Platinum-Resistant Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Cancer
Interventions: DRUG: Durvalumab|DRUG: Pegylated Liposomal Doxorubicin|DRUG: Motolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacist-initiated Intervention Trial in OsteoArthritis (PhIT-OA)
Status: COMPLETED
Conditions: Knee Osteoarthritis
Interventions: PROCEDURE: Pharmacist-Initiated Intervention in OsteoArthritis (PhIT-OA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of a Hospital Physical Therapy Program on Chronic Obstructive Pulmonary Disease (COPD) Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Ground Walking Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transarterial Chemoembolization (TACE) Versus TACE Plus Stereotactic Body Radiation Therapy (SBRT) in Liver Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: RADIATION: Stereotactic Body Radiation|DRUG: Transarterial Chemoembolization
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunotherapy Based on Antigen-specific Immune Effector Cells Targeting Neurofibromatosis or Schwannomatosis
Status: UNKNOWN
Conditions: Cancer
Interventions: BIOLOGICAL: Antigen-specific T cells CART/CTL and DCvac
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Triacylglycerol Structure on Gut Hormones and Haemostatic Markers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: OTHER: Native palm olein (IV56)|OTHER: Chemically interesterified palm olein (IV56)|OTHER: High oleic sunflower oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Whole Grain Cereal Product on Blood Glucose Response After 3 Consecutive Meals
Status: COMPLETED
Conditions: Blood Glucose
Interventions: OTHER: Breakfast product: Whole grain|OTHER: Breakfast product: Reference
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of Antimicrobial Activity of Omiganan 1% Gel vs. Chlorhexidine 2% for Topical Skin Antisepsis in Healthy Adult Subjects
Status: COMPLETED
Conditions: Infection
Interventions: DRUG: omiganan 1% gel|DRUG: chlorhexidine 2% solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Status: COMPLETED
Conditions: Postmenopausal Women|Locally Advanced Metastatic Breast Cancer|Metastatic Breast Cancer
Interventions: DRUG: Everolimus|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of The Surgical Drain Placement With Use of Kinesiologic Tape
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: PROCEDURE: Kinesiologic Tape Group|PROCEDURE: Drain Group|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Amodiaquine Plus Artesunate Versus Lapdap Plus Artesunate in the Treatment of Uncomplicated P. Falciparum Malaria in Malawi
Status: COMPLETED
Conditions: Malaria, Falciparum
Interventions: DRUG: Amodiaquine plus artesunate|DRUG: chlorproguanil-dapsone plus artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Masticatory Side-switch and Mixing Ability.
Status: COMPLETED
Conditions: Chewing Problem|Mastication Disorder
Interventions: BEHAVIORAL: F|BEHAVIORAL: R|BEHAVIORAL: L|BEHAVIORAL: G05|BEHAVIORAL: G15|BEHAVIORAL: G25
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Anesthesia Endoscope Mask is Applied to Sedation Upper Gastrointestinal Endoscopic Diagnosis and Treatment
Status: RECRUITING
Conditions: Hypoxemia
Interventions: DEVICE: Routine nasal catheter group|DEVICE: Mask group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lung-Resident Memory Th2 Cells in Asthma
Status: RECRUITING
Conditions: Asthma, Allergic
Interventions: PROCEDURE: Bronchoscopy/BAL|PROCEDURE: Airway Brushing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Pelcitoclax (APG-1252) in Patients With Neuroendocrine Tumors
Status: RECRUITING
Conditions: Neuroendocrine Tumors
Interventions: DRUG: Pelcitoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABCSG 8 - Adjuvant Treatment in Patients With Hormone Receptor-positive Breast Cancer With Good to Moderate Differentiation.
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Tamoxifen|DRUG: Anastrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improvement of Functional Dyspepsia After Drinking Alkaline Ionized Water From Alkaline Ionizer
Status: COMPLETED
Conditions: Functional Dyspepsia
Interventions: DEVICE: Electrolyzed Alkaline Reduced Water (EARW) generated from electrolyzed ionizer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ex-situ Normothermic Perfusion Versus Cold Storage in the Transplant With Steatotic Liver Graft.
Status: TERMINATED
Conditions: Liver Transplant
Interventions: PROCEDURE: Static cold storage (SCS)|DEVICE: Normothermic machine perfusion (NMP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of Modified Dental Visual Aids on Behavior Management During Dental Treatment in Children With Autism Spectrum Disorder
Status: COMPLETED
Conditions: Child Autism
Interventions: OTHER: Modified dental visual aids|OTHER: Regular dental visual aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Normal Versus Dual Wave Insulin Bolus for High-protein Food
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DRUG: insulin aspart|DRUG: insulin lispro|DRUG: insulin glulisine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mirabegron for the Treatment of Pain Motivated Urinary Frequency and Urgency in Women
Status: WITHDRAWN
Conditions: Urinary Frequency/Urgency|Bladder Irritable|Bladder Pain Syndrome
Interventions: DRUG: Mirabegron
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy.
Status: TERMINATED
Conditions: Epilepsy|Seizures
Interventions: DRUG: carisbamate|DRUG: topiramate|DRUG: levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes
Status: COMPLETED
Conditions: Apraxia of Speech|Aphasia
Interventions: BEHAVIORAL: Combined Aphasia and Apraxia of Speech Treatment (CAAST)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contingency Management to Enhance Office-Based Buprenorphine Treatment
Status: COMPLETED
Conditions: Opioid-use Disorder
Interventions: BEHAVIORAL: Contingency Management for adherence|BEHAVIORAL: Contingency Management for abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase 2 Study to Evaluate DNTH103 in Adults With Generalized Myasthenia Gravis (MAGIC)
Status: RECRUITING
Conditions: Myasthenia Gravis, Generalized
Interventions: DRUG: DNTH103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maintaining Intrauterine Devices (IUDs) in Teens (MINT): A Randomization Trial
Status: COMPLETED
Conditions: Contraception
Interventions: DEVICE: Levonorgestrel-releasing intrauterine device (LNG-IUS)|DEVICE: Copper T380A intrauterine device (CuT380A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Uterine Natural Killer (uNK) Cell Expression in Patients With Repeated ICSI Failures: A Multicenter Cohort Study
Status: RECRUITING
Conditions: Repeated Implantation Failure|ICSI Failure|uNatural Killer Cells
Interventions: PROCEDURE: Endometrial Biopsy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda
Status: COMPLETED
Conditions: HIV|Acquired Immunodeficiency Syndrome|Influenza
Interventions: DRUG: Seasonal trivalent inactivated influenza vaccine (Vaxigrip®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Assessment of Intracameral Injection of T2380 in Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DRUG: T2380|DRUG: Mydriatics|DRUG: Tetracaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of MHS552 in Adults With Type 1 Diabetes Mellitus
Status: WITHDRAWN
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: MHS552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prasugrel With Lower Dose - Loading Dose
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Clopidogrel 600 mg|DRUG: Prasugrel 30 mg|DRUG: Prasugrel 60 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study Between the Different Levels of TMJ Arthroscopy in the Management of TMJ Internal Derangement
Status: COMPLETED
Conditions: TMJ Disc Disorder
Interventions: PROCEDURE: three levels of TMJ arthroscopy|PROCEDURE: three levels of TMJ arthroscopy|PROCEDURE: three levels of TMJ arthroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Trilaciclib Combined With Concurrent Chemoradiotherapy and Immunotherapy in the Treatment of Esophageal Cancer
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: DRUG: Trilaciclib Injection [Cosela]|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Midodrine as Novel Treatment of Post-Cardiopulmonary Bypass Vasoplegic Syndrome
Status: TERMINATED
Conditions: Use of Midodrine in Post-cardiopulmonary Bypass Vasoplegic Syndrome
Interventions: DRUG: Midodrine|DRUG: Methylcellulose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Treating Staphylococcus Aureus Infection and Colonization on the Clinical Severity of Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Sodium hypochlorite (bleach) baths|DRUG: Mupirocin ointment|DRUG: Water|DRUG: Petrolatum Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of Autologous Adipocytes Graft in Endoscopic Treatment in Vesico-Renal Reflux in Children
Status: UNKNOWN
Conditions: Vesico-Ureteral Reflux
Interventions: PROCEDURE: endoscopic treatment of vesico-renal reflux
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Sulphur Mineral, Thermal Water on Skin Microbiome in Plaque Psoriasis, a Pilot Study
Status: UNKNOWN
Conditions: Plaque Psoriasis
Interventions: OTHER: balneotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Hyperbaric Oxygen Compared to Pharmaceutical Therapies for Fibromyalgia Syndrome
Status: COMPLETED
Conditions: Fibromyalgia|Hyperbaric Oxygen
Interventions: DEVICE: Hyperbaric oxygen therapy (HBOT) treatment|DRUG: Cymbalta / Lyrica treatment|DEVICE: Crossover Hyperbaric oxygen therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1 ID93 + GLA-SE Vaccine Trial in BCG-Vaccinated Healthy Adult Volunteers
Status: COMPLETED
Conditions: Pulmonary Tuberculosis
Interventions: BIOLOGICAL: ID93 + GLA-SE|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Prolongation of the Interval Between Monitoring of Warfarin in Stable Patients
Status: COMPLETED
Conditions: Atrial Fibrillation|Heart Valve Diseases|Venous Thrombosis
Interventions: DRUG: Dosing warfarin every 12 weeks, sham INRs 2 out of 3 times
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Status: ACTIVE_NOT_RECRUITING
Conditions: Myelodysplastic Syndrome|Hodgkin's Lymphoma|Non-Hodgkin's Lymphoma|Acute Leukemia|Multiple Myeloma
Interventions: BIOLOGICAL: Rituximab|DRUG: Conditioning chemotherapy|DRUG: TMS|DRUG: FLAG|DRUG: EPOCH-F|PROCEDURE: Hematopoietic stem cell transplant|DRUG: Palifermin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Test of the Nipro ELISIO H Dialyzer in Different Dialysis Treatment Procedures
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DEVICE: treatment with the dialyzer ELISIO 170H|DEVICE: treatment with the dialyzer PES-170DS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Crossover Study of Blood Pressure and Heart Rate Response
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: TR-701 FA with PSE|OTHER: TR-701 FA Placebo with PSE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Investigation of the Effect of Mobile Software Use in Blood Pressure Management of Hypertensive Individuals on Quality of Life and Disease Self-Efficacy
Status: NOT_YET_RECRUITING
Conditions: Hypertension, Essential Hypertension
Interventions: OTHER: mobile application
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Hyperbaric Oxygen Therapy for Lung Transplantation
Status: COMPLETED
Conditions: Disorder Related to Lung Transplantation|Central Airway Stenosis|Airway Exudative Plaques|Airway Complications Post-Lung Transplantation
Interventions: DRUG: Hyperbaric Oxygen Therapy|PROCEDURE: Endobronchial Biopsy of Airway Epithelium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma|Recurrent Soft Tissue Sarcoma
Interventions: BIOLOGICAL: Pembrolizumab|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can Atorvastatin Improve Vascular Function in Women With a History of Preeclampsia?
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DRUG: Atorvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Randomized, Multicenter Pragmatic Trial Comparing Bone Pain From a Single Dose of Pegfilgrastim to 5 Doses of Daily Filgrastim in Breast Cancer Patients Receiving Neoadjuvant/Adjuvant Chemotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Early-stage Breast Cancer
Interventions: DRUG: Filgrastim|DRUG: Pegfilgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Correlation of COX-2 Expression in Human Polymorphonuclear Leukocytes/Macrophages (PMNL/MP) and Postoperative Pain
Status: COMPLETED
Conditions: Post-Operative Pain
Interventions: DRUG: Parecoxib Sodium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychosocial Intervention in Assisted Reproduction Treatments
Status: COMPLETED
Conditions: Infertility Primary|Psychosocial Stressor|Anxiety Depression
Interventions: OTHER: Group psychosocial intervention|OTHER: Couple psychosocial intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Enhanced Recovery After Surgery Using TMS on Cerebellar Language Area for Brain Tumor Patients
Status: UNKNOWN
Conditions: Cerebellar Function|Transcranial Magnetic Stimulation|Language Disorders
Interventions: COMBINATION_PRODUCT: Transcranial magnetic stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children
Status: RECRUITING
Conditions: Respiratory Diseases|Congenital Heart Defects
Interventions: COMBINATION_PRODUCT: The use of a combination of microelements and vitamins against the background of physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Clinical Trial to eLiminate HCV-infection in Treatment-naïve, Renally Impaired EgyptiAn Patients on Renal Dialysis, With Chronic Hepatitis C Genotype 4
Status: WITHDRAWN
Conditions: Hepatitis C Virus Infection, Response to Therapy of
Interventions: DRUG: Elbasvir/Grazoprevir 50 MG-100 MG Oral Tablet [ZEPATIER]
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Different Modalities of Cryotherapy on Post-Operative Pain in Patients With Symptomatic Irreversible Pulpitis
Status: NOT_YET_RECRUITING
Conditions: Endodontic Disease|Endodontically Treated Teeth
Interventions: DRUG: Saline|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Innovative Intervention for OUD Treatment
Status: RECRUITING
Conditions: Opioid-Related Disorders|Opioid Dependence|Opioid Addiction|Opioid Withdrawal
Interventions: DEVICE: Bridge Device|DRUG: Lofexidine|DRUG: Placebo|DEVICE: Sham Bridge Device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: rTMS in Spastic Hemiplegic Cerebral Palsy Children
Status: UNKNOWN
Conditions: Cerebral Palsy
Interventions: DEVICE: Repetitive Transcranial Magnetic Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia
Status: TERMINATED
Conditions: Trigeminal Neuralgia
Interventions: DRUG: Amifostine|PROCEDURE: CyberKnife stereotactic radiosurgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Tele-Nursing Application on Self-Care Ability and Daily Living Activities in Fracture Surgery Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Lower Extremity Fracture
Interventions: OTHER: post-discharge telenursing intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Treatment of Liver Metastases With Electrochemotherapy (ECTJ) Phase II
Status: COMPLETED
Conditions: Liver Metastases
Interventions: PROCEDURE: Electrochemotherapy|DEVICE: Cliniporator Vitae®|DRUG: Bleomycin PHC 15 e. (United States Pharmacopeia - USP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer
Status: COMPLETED
Conditions: Cervical Adenocarcinoma|Cervical Adenosquamous Carcinoma|Cervical Small Cell Carcinoma|Cervical Squamous Cell Carcinoma|Recurrent Cervical Carcinoma
Interventions: DRUG: Paclitaxel Albumin-Stabilized Nanoparticle Formulation|OTHER: Laboratory Biomarker Analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Extended Treatments for Drug Dependence
Status: COMPLETED
Conditions: Cocaine Dependence
Interventions: OTHER: Intensive Outpatient Treatment|OTHER: Adaptive telephone-based counseling|OTHER: Adaptive telephone-based counseling plus incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ginseng for Patients on Regorafenib
Status: TERMINATED
Conditions: Colorectal Cancer|Palliative Medicine|Supportive Care
Interventions: DRUG: Regorafenib|DIETARY_SUPPLEMENT: Ginseng
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection
Status: TERMINATED
Conditions: Brain Tumor|High Grade Glioma
Interventions: DRUG: topotecan|DEVICE: Cleveland Multiport Catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outcome After MTX & Transvaginal Surgery or UAE & Uterine Curettage in Patients With Cesarean Scar Pregnancy
Status: UNKNOWN
Conditions: Cesarean Scar Pregnancy|Menstruation
Interventions: PROCEDURE: Methotrexate Combined With Transvaginal Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dusting vs Basketing in RIRS: a Single-center Prospective Randomised Trial
Status: UNKNOWN
Conditions: Urolithiasis
Interventions: PROCEDURE: Basketing in RIRS|PROCEDURE: Dusting in RIRS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Open Label Study of BOTOX® (Botulinum Toxin Type A) as Headache Prophylaxis in Chinese Patients With Chronic Migraine
Status: WITHDRAWN
Conditions: Migraine Disorders
Interventions: BIOLOGICAL: botulinum toxin Type A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation on Post-cryopreserved Sperm Quality
Status: RECRUITING
Conditions: Autologous Platelet-rich Plasma Supplement|Sperm Cryopreservation|Post-cryopreserved Sperm Quality|Semen Analysis
Interventions: BIOLOGICAL: autologous platelet-rich plasma supplement|BIOLOGICAL: no autologous platelet-rich plasma supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Dabrafenib and Trametinib in Treating Patients With BRAF Mutated Ameloblastoma
Status: COMPLETED
Conditions: Ameloblastoma|BRAF Gene Mutation
Interventions: DRUG: Dabrafenib|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Imaging Histone Deacetylase in the Heart
Status: UNKNOWN
Conditions: Heart Failure With Normal Ejection Fraction|Left Ventricular Hypertrophy|Aortic Valve Stenosis|Diabetes
Interventions: DRUG: 11C-Martinostat|DEVICE: PET-MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Voriconazole And Anidulafungin Combination For Invasive Aspergillosis In Pediatric Subjects
Status: WITHDRAWN
Conditions: Aspergillosis|Invasive Pulmonary Aspergillosis|Neuroaspergillosis
Interventions: DRUG: Voriconazole|DRUG: Anidulafungin|DRUG: Voriconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Intranasal Insulin in Type 1 Diabetes and Diabetic Peripheral Neuropathy
Status: COMPLETED
Conditions: Diabetic Peripheral Neuropathy
Interventions: DRUG: Novolin Toronto insulin|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Kangaroo Mother Care Applied to the Healthy Newborns on Breastfeeding
Status: COMPLETED
Conditions: Breastfeeding|Kangaroo Mother Care|Breastfeeding, Exclusive
Interventions: OTHER: Kangaroo Mother Care (KMC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Performance Evaluation of Different Daily Disposable Silicone Hydrogel Contact Lenses.
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Control Contact Lens (stenfilcon A)|DEVICE: Test Contact Lens (senofilcon A)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of PROGRESSive Training and Teststerone in Older Frail Men
Status: COMPLETED
Conditions: Muscle Weakness
Interventions: DRUG: testosterone|OTHER: Progressive muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HFNC vs Nasal Cannula in Mild Chronic Obstructive Pulmonary Disease Exacerbation
Status: UNKNOWN
Conditions: COPD Exacerbation
Interventions: DEVICE: High flow nasal cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms
Status: COMPLETED
Conditions: Aortic Aneurysm, Thoracic
Interventions: DEVICE: GORE TAG® Thoracic Endoprosthesis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses
Status: RECRUITING
Conditions: Major Depressive Disorder|Depression
Interventions: DRUG: Buprenorphine|DRUG: Naltrexone|DRUG: Oral Placebo|DRUG: IM Placebo|DEVICE: Theta burst stimulation (TBS) of the ventromedial prefrontal cortex.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Fasting Study of Doxycycline Monohydrate Tablets 150 mg and Adoxa Tablets 150 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Doxycycline Tablets, 150mg|DRUG: Adoxa Tablets 150 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Chronic Non-Healing Venous Leg Ulcers
Status: UNKNOWN
Conditions: Venous Leg Ulcer|Autologous Adipose Stromal Vascular Fraction|Adipose-Derived Mesenchymal Stem Cells|Mesenchymal Stem Cells
Interventions: DEVICE: Venous leg ulcer treatment with adipous SVF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Treatment of Local Gingival Recession With an Enamel Matrix Protein Coated Collagen Matrix
Status: COMPLETED
Conditions: Gingival Recession
Interventions: DEVICE: Use of coronally advanced flap (CAF) and collagen matrix (CM)|DEVICE: Use of coronally advanced flap (CAF) and collagen matrix (CM) and additional application of enamel matrix derivatives (EMD).
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Imatinib Mesylate as First-line Treatment for the Patients With Chronic Phase of Chronic Myeloid Leukemia
Status: UNKNOWN
Conditions: Chronic Myeloid Leukemia
Interventions: DRUG: Imatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Lettuce With Different Nitrate Contents on Blood Pressure
Status: COMPLETED
Conditions: Dietary Modification|Blood Pressure
Interventions: DIETARY_SUPPLEMENT: High Nitrate Lettuce|DIETARY_SUPPLEMENT: Low Nitrate Lettuce
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety Study of Increasing Doses of CKD-516 in Patients With Advanced Solid Cancers
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: CKD-516 inj
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Broccoli Sprout Extract in Preventing Recurrence in Patients With Tobacco-Related Head and Neck Squamous Cell Cancer
Status: COMPLETED
Conditions: HNSCC|Head and Neck Cancer|Head and Neck Squamous Cell Carcinoma|Tobacco-Related Carcinoma|Carcinoma in Situ|Dysplasia|Hyperplasia|Premalignant Lesion
Interventions: DRUG: Avmacol®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors
Status: COMPLETED
Conditions: Part 1|MELANOMA|SCCHN|OVCA|SARCOMA|OTHER SOLID TUMORS|Part 1 and 2|NSCLC|UROTHELIAL CARCINOMA
Interventions: DRUG: PF-06801591|DRUG: PF-06801591
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: GSK3745417|DRUG: Dostarlimab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of iTero Element 5D NIRI System in Early Proximal Caries Detection in Permanent Teeth
Status: RECRUITING
Conditions: Dental Caries
Interventions: DIAGNOSTIC_TEST: intraoral scanning|DIAGNOSTIC_TEST: clinical oral examination|DIAGNOSTIC_TEST: cone-beam computed tomography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MRI Functional Imaging Characteristics and Fat Quantification of CT-fat-free Renal Neoplasms: Relationships With Histological Classifications and Molecular Markers
Status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Neoplasms
Interventions: DIAGNOSTIC_TEST: multiparametric and fat-detection magnetic resonance imaging (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: To Evaluate Skin Irritation and Skin Sensitisation of Developmental Cosmetic Facial Products
Status: COMPLETED
Conditions: Skin Care
Interventions: OTHER: Serum|OTHER: Lotion|OTHER: Cream|OTHER: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE