pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Effect of Transcutaneous Electro-stimulation in Ambulatory Postoperative Rehabilitation Treatment in Thoracic Surgery.
Status: COMPLETED
Conditions: Thoracic|Postoperative Pain
Interventions: DEVICE: Control|DEVICE: Experimental|DEVICE: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Convalescent Plasma Treatment in Severe 2009 H1N1 Infection
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: H1N1 convalescent plasma and oseltamivir|DRUG: Oral Oseltamivir alone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Injury Mental Health Functional Outcomes Improved by Mindfulness
Status: COMPLETED
Conditions: Spinal Cord Injuries|Mindfulness Meditation|Mental Health Wellness 1
Interventions: BEHAVIORAL: Mindfulness meditation (MM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Mirdametinib in Histiocytic Disorders
Status: RECRUITING
Conditions: Langerhans Cell Histiocytosis (LCH)|Juvenile Xanthogranuloma (JXG)|Rosai-Dorfman Disease (RDD)|Histiocytic Disorders
Interventions: DRUG: Mirdametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Adhesion Performance Study of Lidocaine Topical System 1.8% Compared to Lidocaine Patch 5% and Lidocaine Medicated Plaster 5% in Healthy, Adult, Human Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lidocaine patch 1.8%|DRUG: Lidocaine patch 5%|DRUG: Lidocaine medicated plaster 5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Popular Weight Loss Diets
Status: COMPLETED
Conditions: Obesity
Interventions: BEHAVIORAL: Atkins diet (extremely low carbohydrate)|BEHAVIORAL: Zone diet (low carbohydrate, high protein)|BEHAVIORAL: Ornish diet (very low fat)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Is There a Difference in Oocyte Quality? A Comparison of Two Aspiration Needle Gauges
Status: UNKNOWN
Conditions: Infertility
Interventions: DEVICE: Oocyte Aspiration needle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oxymatrine Plus Lamivudine Combination Therapy Versus Lamivudine Monotherapy for Chronic Hepatitis B Infected Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Lamivudine|DRUG: Lamivudine+Oxymatrine Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLC
Status: TERMINATED
Conditions: Non Small Cell Lung Cancer|Non-Small Cell Lung Cancer|NSCLC|Advanced Solid Tumor|Metastatic Solid Tumor|ALK Gene Mutation
Interventions: DRUG: TPX-0131
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oxytocin Effects on Bone Metabolism in Children With Autism Spectrum Disorder
Status: RECRUITING
Conditions: Autism Spectrum Disorder|Bone Health
Interventions: DRUG: 1. Intranasal oxytocin spray|DRUG: 2. Intranasal placebo spray|DRUG: 3. Intranasal Oxytocin spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: ABT-263|DRUG: erlotinib|DRUG: irinotecan (3-week schedule)|DRUG: irinotecan (weekly schedule)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lactobacillus Rhamnosus in Prevention of Chemotherapy-related Diarrhoea
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DIETARY_SUPPLEMENT: Lactobacillus Rhamnosus supplementation|OTHER: Placebo administration.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Vaginal Estrogen for the Prevention of Recurrent Urinary Tract Infection in Postmenopausal Women
Status: COMPLETED
Conditions: Recurrent Urinary Tract Infection
Interventions: DRUG: Conjugated Estrogen Vaginal Cream|DRUG: Estradiol Ring|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Diuretic Strategies in Acute Heart Failure Patients at High Risk for Diuretic Resistance
Status: RECRUITING
Conditions: Acute Heart Failure|Diuretic Resistance
Interventions: DRUG: Furosemide|DRUG: Metolazone|DRUG: Acetazolamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lidocaine-prilocaine Cream on IUD Insertion Pain
Status: COMPLETED
Conditions: IUD Pain
Interventions: DRUG: lidocaine-Prilocaine cream|DRUG: placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Educatıon in Patıents Who Had Total Knee Prosthesıs
Status: NOT_YET_RECRUITING
Conditions: Prosthesis-Related Infections|Pain, Postoperative|Analgesia
Interventions: BEHAVIORAL: education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec/liraglutide|DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Aesthetic Reconstruction of Onco-surgical Mandibular Defects Using FFF With and Without CAD/CAM Customized Cutting Guide
Status: UNKNOWN
Conditions: Mandibular Tumors
Interventions: PROCEDURE: FFF with CAD/CAM customized cutting guide|PROCEDURE: FFF without customized cutting guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread
Status: RECRUITING
Conditions: Metastatic Urothelial Cancer
Interventions: DRUG: Sacituzumab Govitecan-hziy|DRUG: Pembrolizumab|DRUG: Cisplatin|DRUG: Avelumab|DRUG: Zimberelimab|DRUG: Carboplatin|DRUG: Gemcitabine|DRUG: Domvanalimab|DRUG: Enfortumab Vedotin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Self-managed Approaches for Patellofemoral Pain Syndrome in Active Duty
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome
Interventions: OTHER: Home Exercise Program (HEP)|DEVICE: NMES|DEVICE: TENS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Study of BCG Vaccine for Intradermal Injection
Status: COMPLETED
Conditions: Tuberculosis
Interventions: BIOLOGICAL: BCG vaccine 1（0.025mg/0.1ml/person）|BIOLOGICAL: BCG vaccine 2 （0.05mg/0.1ml/person）|BIOLOGICAL: BCG vaccine 3（0.075mg/0.1ml/person）|BIOLOGICAL: BCG vaccine 4 （0.075mg/0.1ml/person）|BIOLOGICAL: Placebo of BCG vaccine （0.1ml/person）
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Vorinostat With Gemcitabine, Busulfan, and Melphalan With Stem Cell Transplant (SCT) in Relapsed or Refractory Lymphoid Malignancies
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: Vorinostat|DRUG: Gemcitabine|DRUG: Busulfan|DRUG: Melphalan|PROCEDURE: Stem Cell Infusion|DRUG: Rituximab|DRUG: G-CSF|DRUG: Palifermin|DRUG: Dexamethasone acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Trial of a Malaria Vaccine in Young Kenyan Children
Status: COMPLETED
Conditions: Plasmodium Falciparum Malaria
Interventions: BIOLOGICAL: FMP1/AS02A Malaria vaccine|BIOLOGICAL: Imovax Rabies vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Study of PF-04991532 in Healthy Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus|Diabetes Mellitus, Type 2|Glucose Metabolism Disorders
Interventions: DRUG: PF-04991532|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: A Prospective Study of Combination of Peginterferon Alfa-2b (40kD, Y-shape) and GM-CSF in Chronic Hepatitis B
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Ypeginterferon alfa-2b|DRUG: Granulocyte-macrophage colony stimulating factor
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-il6 Treatment of Serious COVID-19 Disease With Threatening Respiratory Failure
Status: TERMINATED
Conditions: Corona Virus Disease
Interventions: DRUG: RoActemra iv|DRUG: RoActemra sc|DRUG: Kevzara sc|OTHER: Standard medical care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy, Radiographic and Laboratory Changes in Refractory Rheumatoid Arthritis Patients Treated With H.P. Acthar Gel
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: H.P. Acthar gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BRIA-OTS Cellular Immunotherapy in Metastatic Recurrent Breast Cancer
Status: RECRUITING
Conditions: Breast Cancer|Breast Tumor|Cancer of Breast|Cancer of the Breast|Malignant Tumor of Breast|Tumors, Breast
Interventions: BIOLOGICAL: BC1 cell line|BIOLOGICAL: Bria-OTS regimen and CPI (tislelizumab)|BIOLOGICAL: Bria-OTS regimen and CPI (tislelizumab) expansion cohort
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Refresh Optive® Gel Drops|DRUG: REFRESH LIQUIGEL®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MIROCALS: Modifying Immune Response and OutComes in ALS
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: Riluzole|DRUG: IL-2|DRUG: 5% glucose water solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects
Status: COMPLETED
Conditions: Acute Graft-versus-host Disease
Interventions: DRUG: Itacitinib|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micra Transcatheter Pacing Study
Status: COMPLETED
Conditions: Class I or II Indication for Implantation of a Single Chamber Ventricular Pacemaker According to ACC/AHA/HRS 2001 Guidelines and Any National Guidelines
Interventions: DEVICE: Micra Pacemaker Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Safety and Tolerability of Budesonide Foam in Participants With Active Ulcerative Proctitis or Proctosigmoiditis
Status: TERMINATED
Conditions: Proctitis|Proctosigmoiditis
Interventions: DRUG: Budesonide Foam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus
Status: COMPLETED
Conditions: Lichen Planus, Oral
Interventions: BIOLOGICAL: buccal cavity sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
Status: RECRUITING
Conditions: Peripartum Cardiomyopathy, Postpartum
Interventions: DRUG: Bromocriptine|DRUG: Placebo|DRUG: Guideline Directed Medical Therapy for Heart Failure (GDMT)|DRUG: Rivaroxaban|DRUG: Second Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study To Evaluate The Effect Of Topiramate On Clinical And Electrophysiological Parameters In Subjects With Diabetic Peripheral Polyneuropathy
Status: COMPLETED
Conditions: Diabetic Neuropathies|Diabetes Mellitus, Type 2|Polyneuropathies
Interventions: DRUG: Topiramate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Adenocarcinoma|Endometrial Clear Cell Adenocarcinoma|Endometrial Mixed Cell Adenocarcinoma|Endometrial Serous Adenocarcinoma|Endometrial Undifferentiated Carcinoma|Recurrent Uterine Corpus Cancer
Interventions: OTHER: Laboratory Biomarker Analysis|DRUG: Trametinib|DRUG: Uprosertib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation
Status: RECRUITING
Conditions: Recurrent Transformed Chronic Lymphocytic Leukemia|Refractory Transformed Chronic Lymphocytic Leukemia|Richter Syndrome
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Bone Marrow Biopsy|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Ibrutinib|BIOLOGICAL: Lisocabtagene Maraleucel|BIOLOGICAL: Nivolumab|PROCEDURE: Pheresis|PROCEDURE: Positron Emission Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients With Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission
Status: COMPLETED
Conditions: Fallopian Tubes|Ovarian Cancer|Peritoneal Cancer
Interventions: BIOLOGICAL: Globo-H-GM2-sTn-TF-Tn-KLH conjugate, plus the immunological adjuvant QS-21
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Serratus Plane Block for the Prevention of Chronic Pain After Breast Cancer Surgery
Status: UNKNOWN
Conditions: Breast/Surgery|Postoperative Complication|Chronic Pain
Interventions: PROCEDURE: serratus plane bloc : Ropivacaine 2mg/ml (0,3ml/kg)|PROCEDURE: tissue infiltration : Ropivacaine 2mg/ml (0,3ml/kg)|PROCEDURE: serratus plane bloc : placebo|PROCEDURE: tissue infiltration : placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Non-inferiority of the Robotic Approach Over the Laparoscopic Approach in Patients Who Are Candidates for Single Anastomosis Duodeno-ileal Bypass With Sleeve Gastrectomy (SADI-S)
Status: NOT_YET_RECRUITING
Conditions: Obesity, Morbid
Interventions: PROCEDURE: SADI-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Resistance vs. Aerobic Training on Breast Cancer Patients Undergoing Neoadjuvant Treatment
Status: RECRUITING
Conditions: Breast Cancer
Interventions: BEHAVIORAL: Aerobic Training Group|BEHAVIORAL: Resistance Training Group|OTHER: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Comparison of Warfarin Dosing Using Decision Model Versus Pharmacogenetic Algorithm
Status: COMPLETED
Conditions: Atrial Fibrillation|Pulmonary Embolism|Deep Vein Thrombosis
Interventions: GENETIC: Warfarin Dose based on pharmacogenetics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Efavirenz
Status: COMPLETED
Conditions: Malaria
Interventions: DRUG: Ganaplacide|COMBINATION_PRODUCT: Lumefantrine|DRUG: Efavirenz
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVIG (Gamunex-C) Treatment Study for POTS Subjects
Status: COMPLETED
Conditions: Postural Tachycardia Syndrome
Interventions: DRUG: IVIG|DRUG: Albumin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: VeraFlo With Prontosan® and Wound and Fracture Healing.
Status: TERMINATED
Conditions: Infection
Interventions: DRUG: VeraFlo with Prontosan|DEVICE: V.A.C Ulta System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Test 2 Doses of the HRV Vaccine in Healthy Infants.
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotavirus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surgical Site Infections After Liver Transplantation Based on Perioperative Antibiotics
Status: COMPLETED
Conditions: Liver Transplantation|Surgical Site Infection
Interventions: DRUG: standard|DRUG: extended|OTHER: liver transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Evaluating The Efficacy Of Etanercept In Acute Gout
Status: TERMINATED
Conditions: Gout Attack
Interventions: DRUG: Etanercept|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Chest Physiotherapy Exercise in Prevention of Pre and Post Operative Complications By Cardiac Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Surgery-Complications
Interventions: DIAGNOSTIC_TEST: Incentive Spirometer|DIAGNOSTIC_TEST: Numeric Pain Rating Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blinded Dry Mouth Spray Crossover Study
Status: COMPLETED
Conditions: Xerostomia|Head and Neck Cancer|Xerostomia Following Radiotherapy
Interventions: OTHER: Remineralizing Extreme Dry Mouth Spray with Xylitol|DEVICE: Alcohol-Free Moisturizing Dry Mouth Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: Molidustat(BAY85-3934)|DRUG: Molidustat(BAY85-3934)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Bronchodilatory Efficacy of a Single Dose QMF149 (Indacaterol Maleate/Mometasone Furoate) Via the Twisthaler® Device in Adult Patients With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: indacaterol maleate/mometasone furoate|DRUG: placebo to indacaterol maleate/mometasone furoate|DRUG: fluticasone proprionate / salmeterol xinafoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Transvaginal Ultrasound Cervical Length Screening in Singleton Pregnancy With Prior Spontaneous Preterm Birth
Status: UNKNOWN
Conditions: Preterm Birth
Interventions: OTHER: Transvaginal ultrasound cervical length screening
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Erythropoietin for the Repair of Cerebral Injury in Very Preterm Infants
Status: UNKNOWN
Conditions: Intraventricular Hemorrhage of Prematurity
Interventions: DRUG: recombinant human Erythropoietin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
Status: RECRUITING
Conditions: Glioma|Glioblastoma|Brain Tumor
Interventions: PROCEDURE: LITT|RADIATION: Hypofractionated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
Status: RECRUITING
Conditions: Colitis, Ulcerative|Obesity
Interventions: DRUG: Phentermine-Topiramate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gabapentin for Relief of Immediate Postoperative Pain
Status: WITHDRAWN
Conditions: Postoperative Pain
Interventions: DRUG: Gabapentin 600mg|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase I Study of Comparing Single Dose JS005 (Recombinant Humanized Monoclonal Antibody Against IL-17A) With Placebo in Tolerability, Safety, Immunogenicity and Pharmacokinetic in Healthy Volunteers
Status: UNKNOWN
Conditions: Tolerability, Safety, Immunogenicity and Pharmacokinetic of JS005
Interventions: BIOLOGICAL: JS005 (recombinant humanized monoclonal antibody against IL-17A)|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Pharmacokinetic Study to Evaluate the Effect of Antacids on Raltegravir (MK-0518) in HIV-Infected Participants (MK-0518-247)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Raltegravir|DRUG: TUMS® Ultra Strength|DRUG: MINTOX® Maximum Strength
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injection of SHR-A1811 Versus Physician Choiced Treatment in Patients With Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-fu, and Irinotecan
Status: RECRUITING
Conditions: Advanced Colorectal Cancer
Interventions: DRUG: SHR-A1811|DRUG: TAS-102, Regorafenib , Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Cyproheptadine in Hospitalized Patient for COVID-19
Status: UNKNOWN
Conditions: Viral Pneumonia|COVID-19 Pneumonia|Serotonin Syndrome|Platelet Dysfunction
Interventions: DRUG: Cyproheptadine Hydrochloride 4 MG
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine
Status: NOT_YET_RECRUITING
Conditions: PFO - Patent Foramen Ovale|Migraine|Migraine Headache|Migraine Headache, With or Without Aura
Interventions: DEVICE: Biodegradable occluder|DEVICE: Metal occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Femto-laser and Manually Created Clear Corneal Incisions During Cataract Surgery
Status: UNKNOWN
Conditions: Cataract
Interventions: DEVICE: Femtosecond Laser for Cataract Surgery|OTHER: Conventional Cataract Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Safety and Immunogenicity of Conserved Mosaic HIV-1 Vaccines
Status: COMPLETED
Conditions: HIV
Interventions: BIOLOGICAL: ChAdOx1.tHIVconsv1 (C1)|BIOLOGICAL: ChAdOx1.tHIVconsv1 (C1)|BIOLOGICAL: MVA.tHIVconsv3 (M3)|BIOLOGICAL: MVA.tHIVconsv4 (M4)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Determine the Effectiveness of Antimicrobial Healthcare Worker's (HCW) Hands and Clothing
Status: COMPLETED
Conditions: Effectiveness of Antimicrobial Impregnated Scrubs in a Healthcare Setting
Interventions: OTHER: Vestagen scrubs
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Effectiveness Analysis of Armeo Spring Device as a Rehabilitation Treatment in Spinal Cord Injured Patients
Status: COMPLETED
Conditions: Spinal Cord Injury Cervical
Interventions: DEVICE: Training by means of Armeo Spring device|OTHER: Current treatment based on conventional therapy|OTHER: Additional treatment based on conventional therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris
Status: COMPLETED
Conditions: Acne Vulgaris|Acne
Interventions: DRUG: ORG101 - Experimental 1|DRUG: ORG101PL - Placebo 1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Learn About Whether BAYH006689 Causes Skin Irritation When Applied as a Topical Gel in Healthy Participants
Status: RECRUITING
Conditions: Pain|Healthy Volunteers
Interventions: DRUG: Naproxen (BAYH006689)|DRUG: Placebo Gel|DRUG: A solution of 0.9% Saline|DRUG: A solution of 0.2% SLS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care Givers
Status: NOT_YET_RECRUITING
Conditions: Metastatic Pancreatic Adenocarcinoma
Interventions: OTHER: Telemedicine|OTHER: Counseling|OTHER: Best Practice|OTHER: Questionnaire Administration|OTHER: Inrweview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Prevention of Severe Postpartum Hypertension
Status: WITHDRAWN
Conditions: Hypertension
Interventions: DRUG: Furosemide|DRUG: Potassium chloride|DRUG: Placebo #1|DRUG: Placebo #2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients
Status: NOT_YET_RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Delirium
Interventions: OTHER: mEEG assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain
Status: TERMINATED
Conditions: Neuropathic Pain Associated With Diabetic Peripheral Neuropathy
Interventions: DRUG: BAY1817080|DRUG: Placebo for BAY1817080|DRUG: Placebo for Pregabalin|DRUG: Pregabalin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Pivanex in Patients With Chronic Lymphocytic Leukemia
Status: TERMINATED
Conditions: Leukemia, Lymphocytic, Chronic|Lymphoma, Small Lymphocytic
Interventions: DRUG: Pivanex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study to Evaluate TGI-6 in Subjects With Locally Advanced/Metastatic Solid Tumors
Status: RECRUITING
Conditions: Advanced or Metastatic Solid Tumors
Interventions: DRUG: TGI-6 Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA]
Status: ACTIVE_NOT_RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Interventions: GENETIC: ADVM-022|GENETIC: ADVM-022
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
Status: RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Proton Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DEVICE: Vagus Nerve Stimulation|DEVICE: Sham Vagus Nerve Stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Efficacy of PRUcalopride in Critically Ill Patients With Paralytic ILeus
Status: UNKNOWN
Conditions: Paralytic Ileus|Critically Ill
Interventions: DRUG: Prucalopride|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Assess the Use of rEBUS With a Guide Sheath to Increase Transbronchial Lung Biopsy Yield Rate
Status: UNKNOWN
Conditions: Diagnoses Disease|Lung Tumor
Interventions: OTHER: Guide sheath group|OTHER: Conventional group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized, Placebo-Controlled, Double-Blind, Ascending Single and Multiple Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of BMS-963272 in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BMS-963272|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: CardioPET as PET Imaging Agent to Assess Myocardial Perfusion and Fatty Acid Uptake in Known or Suspected CAD Subjects
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: CardioPET™
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching
Status: COMPLETED
Conditions: Dentin Sensitivity|Oral Hygiene
Interventions: DRUG: Test Dentifrice|DRUG: Reference Dentifrice (Aquafresh Cavity Protection)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ivWatch SmartTouch Sensor: Device Validation for Non-Infiltrated Tissues
Status: COMPLETED
Conditions: Infiltration of Peripheral IV Therapy
Interventions: DEVICE: ivWatch Model 400 with SmartTouch and fiber optic sensor
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Neurocircuit Mechanisms of OCD Across the Lifespan
Status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy - Adolescents|BEHAVIORAL: Stress Management Therapy - Adolescents|BEHAVIORAL: Optional CBT - Adolescents|BEHAVIORAL: Cognitive Behavioral Therapy - Adults|BEHAVIORAL: Stress Management Therapy - Adults|BEHAVIORAL: Optional CBT - Adults|OTHER: fMRI only - Healthy Control Adults|OTHER: fMRI only - Healthy Control Adolescents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Study in the Diagnosis of Coronary Plaque
Status: TERMINATED
Conditions: Myocardial Infarction|Coronary Artery Disease|Cardiac Catheterization
Interventions: DIAGNOSTIC_TEST: PET/CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA)
Status: COMPLETED
Conditions: Spinal Muscular Atrophy
Interventions: GENETIC: OAV101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Kaletra and Maraviroc in Antiretroviral Therapy (ART)-Naive Patients (KALMAR Study)
Status: TERMINATED
Conditions: HIV Infections
Interventions: DRUG: lopinavir/ritonavir plus maraviroc
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)
Status: RECRUITING
Conditions: Adenosquamous Carcinoma of the Pancreas
Interventions: DRUG: Minnelide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lucentis® Use in Patients With Diabetic Macular Edema Evaluating a Spaced Out Follow-up After Intensive Treatment Phase
Status: TERMINATED
Conditions: Macular Edema|Macular Degeneration|Diabetes
Interventions: DRUG: Ranibizumab 0.5mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rituximab, Ifosfamide, Carboplatin, and Etoposide (RICE) Followed by Gallium Nitrate, Rituximab and Dexamethasone (GARD) for Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Status: WITHDRAWN
Conditions: Diffuse Large B-cell Lymphoma
Interventions: DRUG: RICE|DRUG: GaRD Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Online Program and Task-related Training for Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease|Occupational Therapy|Telerehabilitation|Activities of Daily Living
Interventions: BEHAVIORAL: on-line self-management training|BEHAVIORAL: onsite task-related training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Perfusion Variation During Blood Pressure Changes in ICU
Status: RECRUITING
Conditions: Intensive Care Unit Syndrome
Interventions: DIAGNOSTIC_TEST: Non-invasive Measurement of cerebral blood velocity in the middle cerebral artery by transcranial pulsed Doppler (TCD) (Mean velocity, Vm, cm/s)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During Cesarean Section
Status: RECRUITING
Conditions: Fetal or Neonatal Effect of Damage to Placenta From Caesarean Section
Interventions: DRUG: Esketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Leronlimab in Combination With Regorafenib in Patients With CCR5+, Metastatic Colorectal Cancer
Status: WITHDRAWN
Conditions: CCR5|Microsatellite Stable|Metastatic|Colorectal Cancer
Interventions: DRUG: 700mg leronlimab weekly dose|DRUG: 80mg Regorafenib at week 1|DRUG: 120mg Regorafenib at week2|DRUG: 160 mg Regorafenib at week 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of DM919 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumor
Interventions: DRUG: DM919|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM
Status: COMPLETED
Conditions: Diabetes
Interventions: DRUG: Sitagliptin|DRUG: Metformin|DRUG: Sitagliptin + Metformin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PTX3-targeted Antifungal Prophylaxis
Status: RECRUITING
Conditions: Candidiasis|Fungal Infection|Acute Myeloid Leukemia|Genetic Predisposition|Aspergillosis
Interventions: DRUG: Posaconazole|DRUG: Fluconazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radical-Dose Image Guided Radiation Therapy in Treating Patients With Metastatic Non-small Cell Lung Cancer Undergoing Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage IV Non-Small Cell Lung Cancer
Interventions: RADIATION: Image-guided Radiation Therapy|DRUG: Immunotherapy (physician's choice for standard of care immunotherapy)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modulation of Free Fatty Acids in Heart Failure Patients With Diabetes: "Effect on Left Ventricular Function"
Status: COMPLETED
Conditions: Heart Failure|Diabetes
Interventions: OTHER: Metabolic substrate modulation|OTHER: metabolic substrate modulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Correlation Between Cotinine and Postoperative Acute and Chronic Pain After Hysterectomy
Status: UNKNOWN
Conditions: Chronic Pain, Acute Pain, Cotinine, Hysterectomy
Interventions: DEVICE: measuring cotinine level
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Response to Supplement and Placebo in GERD
Status: COMPLETED
Conditions: Gastroesophageal Reflux Disease (GERD)|Heartburn|Dyspepsia
Interventions: DRUG: Supplement|DRUG: Placebo|BEHAVIORAL: Expanded Interview|BEHAVIORAL: Standard Interview
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy People
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Co-formulation NNC0480 0389+Semaglutide A 10/1 mg/mL|DRUG: semaglutide 1.34 mg/mL (placebo)|DRUG: Semaglutide 1.34 mg/mL|DRUG: NNC0480-0389 A 10 mg/mL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tocilizumab in Schizophrenia
Status: RECRUITING
Conditions: Schizophrenia|Psychotic Disorders
Interventions: DRUG: Tocilizumab|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: AAB-001 in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: bapineuzumab|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: HIV Prevention Program for Patients Receiving Care at a Sexually Transmitted Diseases Clinic
Status: COMPLETED
Conditions: HIV Infections|Sexually Transmitted Diseases
Interventions: BEHAVIORAL: Brief Motivational Intervention|BEHAVIORAL: Brief Informational Intervention|BEHAVIORAL: Intensive Informational Intervention|BEHAVIORAL: Intensive Info-Motivation-Behavioral Skills Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Blood Transfusion Reduction - QI Project
Status: COMPLETED
Conditions: Blood Transfusion
Interventions: BEHAVIORAL: General improvement|BEHAVIORAL: In-line help text|BEHAVIORAL: Interruptive alert
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of 12-weeks Supplementation of Eubacterium Hallii on Insulin Sensitivity and Glycaemic Control
Status: COMPLETED
Conditions: Pre Diabetes|Impaired Glucose Tolerance|Insulin Sensitivity|Insulin Resistance|Glucose Metabolism Disorders|Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Eubacterium hallii|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Bravelle(follicle stimulating hormone)|OTHER: Saline ( placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Positive Airway Pressure Versus Noninvasive Ventilation in Patients With Overlap Syndrome
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Obstructive Sleep Apnea|Overlap Syndrome
Interventions: PROCEDURE: Bipap procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ridge Preservation Using Xenogenic Bone Graft and Pre-hydrated Collagen Membrane
Status: UNKNOWN
Conditions: Alveolar Bone Resorption|Edentulous Alveolar Ridge
Interventions: DEVICE: Treatment of the dental extraction socket using newly-released biomaterials|DEVICE: Treatment of the dental extraction socket using well-known biomaterials
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
Status: RECRUITING
Conditions: Chronic Kidney Disease and Hypertension
Interventions: DRUG: Baxdrostat/dapagliflozin|DRUG: Dapagliflozin in combination with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Food As Medicine for Heart Failure
Status: COMPLETED
Conditions: Heart Failure|Malnutrition
Interventions: OTHER: Medically-Tailored Meals (MTMs)|DIETARY_SUPPLEMENT: Protein supplementation shakes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Laser + Cryo-thermal Therapy Following Total Knee Replacement Surgery
Status: COMPLETED
Conditions: Knee Arthropathy
Interventions: PROCEDURE: Laser therapy-cryo thermal therapy|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT