pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids
Status: COMPLETED
Conditions: Hemorrhoids|Pain
Interventions: DRUG: Topical 2,5% lidocaine + 2,5% prilocaine gel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Teneligliptin(MP-513) vs. Placebo in Patient With Metformin Monotherapy
Status: COMPLETED
Conditions: Type 2 Diabetes
Interventions: DRUG: MP513|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diagnostic Value of CircRNA-Uck2 for Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Cardiac Disease|Diagnoses Disease|Acute Myocardial Infarction
Interventions: DIAGNOSTIC_TEST: the diagnosis value of cUck2 in acute myocardial infarction.
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: BIOLOGICAL: Gene Directed Enzyme Prodrug Therapy, FP253/Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Inspiratory Muscle Activation Pattern Analysis in Assisting Precision in Inspiratory Muscle Training in Patients With Chronic Respiratory Disease
Status: COMPLETED
Conditions: Chronic Respiratory Disease|Inspiratory Muscle Training|Sternocleidomastoid Muscle|Surface Electromyography
Interventions: OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing Diagnosis Rates While Reducing Examination Time: Can MR Fingerprinting Deliver on Its Promise?
Status: COMPLETED
Conditions: Neurodevelopmental Disorders|Neurodegenerative Diseases|Brain Tumor|Multiple Sclerosis|Epilepsy
Interventions: DIAGNOSTIC_TEST: MRI exam with Magnetic Resonance Fingerprinting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Dose Escalation Study of IBI333 in Subjects With Neovascular Age-related Macular Degeneration
Status: COMPLETED
Conditions: Neovascular Age-related Macular Degeneration
Interventions: BIOLOGICAL: IBI333
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR Correlated Spectroscopic Imaging for Diagnosing Breast Cancer
Status: COMPLETED
Conditions: Benign Breast Neoplasm|Breast Carcinoma|Malignant Breast Neoplasm
Interventions: PROCEDURE: Diffusion Weighted Imaging|PROCEDURE: Magnetic Resonance Spectroscopic Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial of Ridaforolimus Compared to Progestin or Chemotherapy for Advanced Endometrial Carcinoma (MK-8669-007 AM6)
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: DRUG: ridaforolimus|DRUG: medroxyprogesterone acetate tablets OR megestrol acetate|DRUG: chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine the Excretion Balance, Pharmacokinetics, Metabolism and Absolute Oral Bioavailability of a Single Oral Dose of [14C]-Labeled Idasanutlin and an Intravenous Tracer Dose of [13C]-Labeled Idasanutlin in a Single Cohort of Participants With Solid Tumors (Malignancies)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: Idasanutlin|DRUG: Placebo|DRUG: [13C]-radiolabeled Idasanutlin|DRUG: [14C]-radiolabeled Idasanutlin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Transcranial Direct Current Stimulation (tDCS) to Treat Depression
Status: COMPLETED
Conditions: Depressive Disorder, Major|Bipolar Disorder
Interventions: DEVICE: Transcranial direct current stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Initial Prescription of Ketamine and Milnacipran in Depression in Patients With a Progressive Disease
Status: UNKNOWN
Conditions: Depression
Interventions: DRUG: Ketamine|DRUG: Milnacipran|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)
Status: UNKNOWN
Conditions: Permanent Neonatal Diabetes Mellitus
Interventions: DRUG: Sulfonylurea
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SHORTness of Breath In the Emergency Department (SHORTIE)
Status: COMPLETED
Conditions: Acute Myocardial Infarction|Heart Failure|Pulmonary Embolism
Interventions: DEVICE: Triage Profiler S.O.B. Panel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: DIAGNOSTIC
Clinical trial: De-adoption of Oral Chlorhexidine Prophylaxis and Implementation of an Oral Care Bundle (CHORAL)
Status: COMPLETED
Conditions: Mortality|Oral Health|Dryness, Mouth|Pain, Orofacial
Interventions: OTHER: Chlorhexidine Mouth Rinse|OTHER: Chlorhexidine Mouth Rinse De-Adoption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Surgical Approach on Adaptation of Posture-respiratory Coupling
Status: NOT_YET_RECRUITING
Conditions: Resectable Lung Non-Small Cell Carcinoma
Interventions: OTHER: EOS imaging for musculoskeletal disorder|OTHER: Movement analysis by an optoelectronic camera.|OTHER: Stabilometric measurement by strength platform
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of Ficlatuzumab With HiDAC and HiDAC Alone in Adults With Relapsed or Refractory Acute Myeloid Leukemia
Status: WITHDRAWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Ficlatuzumab|DRUG: Cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Diabetes Homeless Medication Support
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Housing Problems|Psychological Distress
Interventions: BEHAVIORAL: Diabetes Homeless Medication Support (D-Homes)|BEHAVIORAL: Enhanced usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
Status: COMPLETED
Conditions: Pit-and-Fissure Sealants
Interventions: BEHAVIORAL: Deliberative Loop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Randomized, Placebo-Controlled Study of the Safety and Efficacy of Efavirenz, Didanosine, and Stavudine in Combination With or Without Hydroxyurea in Antiretroviral Naive or Experienced HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Hydroxyurea|DRUG: Efavirenz|DRUG: Stavudine|DRUG: Didanosine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies
Status: RECRUITING
Conditions: Ewing Sarcoma|Rhabdomyosarcoma|Wilms Tumor|Neuroblastoma|Hepatoblastoma|Germ Cell Tumor
Interventions: DRUG: Vorinostat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-GD2 3F8 Monoclonal Antibody and GM-CSF for High-Risk Neuroblastoma
Status: COMPLETED
Conditions: Neuroblastoma
Interventions: BIOLOGICAL: Anti-GD2 3F8 Monoclonal Antibody|DRUG: GM-CSF (granulocyte-macrophage colony-stimulating factor)|DRUG: oral isotretinoin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study of OCV-C02 in Patients With Advanced or Relapsed Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: OCV-103 and OCV-104|DRUG: OCV-103 and OCV-104|DRUG: OCV-103 and OCV-104|DRUG: OCV-103 and OCV-104
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Homeo-GH (Bone Marrow Derived Clonal Mesenchymal Stem Cell) to Treat Acute/Chronic Graft Versus Host Disease (GVHD)
Status: COMPLETED
Conditions: Graft-vs-Host Disease
Interventions: DRUG: Homeo-GH
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Neoadjuvant 5-fluorouracil, Epirubicin and Cyclophosphamide (FEC) Followed by Weekly Paclitaxel and Trastuzumab in Her2 Positive Breast Cancer
Status: COMPLETED
Conditions: HER-2 Positive Breast Cancer
Interventions: DRUG: Trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study for Evaluation of the Procedure Impact of Mobilization Adapted to Pressure Ulcer Risk for Patients in Intensive Care.
Status: COMPLETED
Conditions: Pressure Ulcers|Nursing Cares|Decubitus Ulcer|Pressure Injury
Interventions: PROCEDURE: Positioning schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Use of Low-cost mHealth Intervention to Enhance Outcomes of Noncommunicable Diseases Care in Rural and Refugee Settings
Status: COMPLETED
Conditions: Diabetes Mellitus|Hypertension
Interventions: OTHER: mHealth intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial of Tivozanib (AV-951) in Combination With Capecitabine (Xeloda®) in Subjects With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Tumors|Locally Advanced or Metastatic Breast or Colorectal Cancer
Interventions: DRUG: tivozanib (AV-951) and capecitabine (Xeloda®)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of a Newborn Behavioral Intervention on the Mental Health of Mothers With Late Pre-Term Infants
Status: COMPLETED
Conditions: Postpartum Depression|Preterm Infant|Infant Development
Interventions: BEHAVIORAL: Newborn Behavioral Observation-Family Wellness (NBO-FW)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Regional Nerve Block on Cancer Recurrence
Status: UNKNOWN
Conditions: Cancer Patient
Interventions: OTHER: Normal saline|OTHER: peripheral Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Mapatumumab in Combination With Paclitaxel and Carboplatin in Subjects With Non-small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: BIOLOGICAL: Mapatumumab|BIOLOGICAL: Mapatumumab|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Using Regular or Rotary Polypectomy Snare for the Resection of Colorectal Polyps
Status: COMPLETED
Conditions: Polypectomy Snare
Interventions: DEVICE: Disposable Polypectomy Snare,JHY-SD-23-230-30-A1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Hospital Fit 2.0 on Patients Physical Activity
Status: COMPLETED
Conditions: Telemedicine|Internal Medicine|Pulmonary Disease
Interventions: DEVICE: Hospital Fit 2.0
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketone Esters in T2DM
Status: UNKNOWN
Conditions: Type 2 Diabetes
Interventions: DIETARY_SUPPLEMENT: Ketone monoesters|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Non-Surgical Treatment for Rotator-Cuff Tears Using Platelet-Rich-Plasma
Status: TERMINATED
Conditions: Partial Tear of Rotator Cuff|Tendinopathy of Rotator Cuff
Interventions: PROCEDURE: PRP injection into PTRCT|DRUG: Subacromial steroid bursal injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intravenous and Intraperitoneal Pharmacokinetics of Dalbavancin in Peritoneal Dialysis Patients
Status: COMPLETED
Conditions: Infectious Peritonitis
Interventions: DRUG: Dalbavancin via Intravenous Administration|DRUG: Dalbavancin via Intraperitoneal Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Chlorhexidine Impregnated Cloths to Prevent Skin and Soft Tissue Infections in Marine Officer Candidates
Status: COMPLETED
Conditions: Staphylococcus Aureus|Community-Acquired Infections|Staphylococcal Skin Infections
Interventions: DRUG: 2% chlorhexidine gluconate (CHG) impregnated cloths|DRUG: Comfort Bath cloths (placebo cloths)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Two Electrotherapy Techniques to Treat Subacromial Impingement Syndrome
Status: COMPLETED
Conditions: Subacromial Impingement Syndrome
Interventions: DEVICE: Transcutaneous nerve stimulation|DEVICE: Interferential Currents
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Metastatic Castration-Resistant Prostate Cancer With Homologous Recombination Deficiency
Status: TERMINATED
Conditions: Metastatic Castration-Resistant Prostate Cancer (mCRPC)|Homologous Recombination Deficiency (HRD)
Interventions: DRUG: Pamiparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Thyroxine Replacement in Organ Donors
Status: COMPLETED
Conditions: Brain Death
Interventions: DRUG: L-thryoxine|DRUG: iv thryoxine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Open Label Trial of Utility of Cryobiopsy in the Multidisciplinary Diagnosis of Idiopathic Interstitial Lung Disease
Status: UNKNOWN
Conditions: Interstitial Lung Disease
Interventions: PROCEDURE: Lung biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hereditary Hemorrhagic Telangiectasia and Neurovascular Manifestations, in the Danish HHT Database
Status: RECRUITING
Conditions: Telangiectasia, Hereditary Hemorrhagic|Intracranial Arteriovenous Malformations
Interventions: OTHER: Brain MRI
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Determination of the Effect of Puzzle Use in Elderly Patients
Status: NOT_YET_RECRUITING
Conditions: Quality of Life|Surgery|Postoperative Confusion|Cognitive Dysfunction
Interventions: OTHER: Puzzle application
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Interbody vs Instrumented Posterolateral Fusion Following Decompression for Lumbar Spinal Stenosis With Degenerative Spondylolisthesis
Status: UNKNOWN
Conditions: Degenerative Spondylolisthesis|Spinal Stenosis
Interventions: PROCEDURE: Interbody Fusion|PROCEDURE: Posterolateral Fusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Infection Rate of Severe Acute Respiratory Syndrome - CoronaVirus 2 (SARS-CoV-2) and It's Affect on Quality of Life in Adult Volunteers in Lake County, Illinois
Status: COMPLETED
Conditions: Severe Acute Respiratory Syndrome - CoronaVirus 2 (SARS-CoV-2)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Nutritional Psychological Intervention and Vomit-free Management on Survival and Quality of Life in Advanced Gastrointestinal Tumors
Status: RECRUITING
Conditions: Digestive System Cancer|Digestive System Neoplasm
Interventions: OTHER: Nutritional psychological interventions and vomit-free management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: 3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: high dose ARA-C|DRUG: standard dose ARA-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GALLEX 6: Study to Evaluate the Safety and Tolerability of Tesaglitazar in Patients With Type 2 Diabetes Mellitus
Status: TERMINATED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Tesaglitazar|DRUG: Pioglitazone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Breakfast Cereals Consumed in Dairy and Non-dairy Medium: the Effects on Blood Glucose, Satiety and Food Intake
Status: COMPLETED
Conditions: Blood Glucose|Eating|Food
Interventions: OTHER: Food
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY2510924 and Sunitinib in Patients With Metastatic Renal Cell Carcinoma
Status: TERMINATED
Conditions: Metastatic Clear Cell Renal Cell Carcinoma
Interventions: DRUG: LY2510924|DRUG: Sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Efficacy Study of Recombinant Human Erythropoietin in Acute Ischemic Stroke
Status: COMPLETED
Conditions: Infarction, Middle Cerebral Artery|Middle Cerebral Artery Stroke|Stroke, Acute
Interventions: DRUG: recombinant human erythropoietin alfa|DRUG: 0.9% NaCl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multiple Ascending Dose Study of AMG 598 in Adults With Obesity
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: AMG 598|DRUG: Placebo|DRUG: Liraglutide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Inferior Vena Cava Collapsibility Index in Severe Sepsis
Status: UNKNOWN
Conditions: Sepsis|Severe Sepsis|Septic Shock
Interventions: OTHER: Ultrasound of the inferior vena cava
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Low Dose Peginterferon-α 2a for Chronic Hepatitis C, Genotypes 2 or 3, in HIV-coinfected Patients
Status: COMPLETED
Conditions: Hepatitis C, Chronic|HIV Infections
Interventions: DRUG: Pegylated interferon alfa-2a and Ribavirin|DRUG: Pegylated interferon alfa 2a and Ribavirin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Capsaicinoid Ingestion, Human Metabolism and Exercise (Phase 2)
Status: WITHDRAWN
Conditions: Metabolism|Exercise
Interventions: DIETARY_SUPPLEMENT: Capsaicin|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Awake Prone Positioning in Moderate to Severe COVID-19
Status: COMPLETED
Conditions: COVID-19|SARS-CoV2 Infection|COVID-19 Acute Respiratory Distress Syndrome|Acute Hypoxemic Respiratory Failure|Respiratory Distress Syndrome, Adult
Interventions: BEHAVIORAL: a wake prone positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Different Local Anesthetic Volumes for Unilateral Spinal Anesthesia
Status: RECRUITING
Conditions: Discharge Time|Ambulatory Surgery|Spinal Anesthesia
Interventions: PROCEDURE: 4 mg bupivacaine|PROCEDURE: 6 mg bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IP Peru, Bioavailability of Iron From Potatoes
Status: COMPLETED
Conditions: Iron-deficiency|Iron Deficiency Anemia|Iron Deficiency (Without Anemia)
Interventions: OTHER: High Fe IP meal labelled with Fe-58|OTHER: Control OFSP meal labelled with Fe-57
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Mechanistic Studies on Video-guided Acupuncture Imagery Treatment of Pain
Status: UNKNOWN
Conditions: Pain
Interventions: OTHER: Real acupuncture|OTHER: Sham acupuncture|OTHER: VGAIT|OTHER: VGAIT control
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Bioequivalence Study of Felodipine ER Tablets 10 mg Under Fed Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Felodipine|DRUG: Felodipine (Plendil®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected Adults
Status: RECRUITING
Conditions: HIV|Acquired Immunodeficiency Syndrome|Immunologic Deficiency Syndrome, Acquired|Sexually Transmitted Diseases, Viral|Retroviridae Infections
Interventions: BIOLOGICAL: Ad26.Mos4.HIV|BIOLOGICAL: MVA-BN-HIV|BIOLOGICAL: PGT121|BIOLOGICAL: PGDM1400|BIOLOGICAL: VRC07-523LS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Dosing of Amicar and Measure of Fibrinolysis by TEG During Cardiac Surgery
Status: TERMINATED
Conditions: Aortic Disease
Interventions: DRUG: epsilon-aminocaproic acid (EACA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients
Status: RECRUITING
Conditions: Interdisciplinary Communication|Postoperative Complications|Noncardiac Surgery|Surgical Procedures, Operative|Preoperative Care|Patient Care Team|Cost-Benefit Analysis|Comorbidities and Coexisting Conditions
Interventions: OTHER: Structured preoperative multidisciplinary team meeting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: First-line mCapOX+Cetuximab vs. mFOLFOX6+Cetuximab for Metastatic Left-sided CRC With Wild-type RAS/BRAF Genes
Status: RECRUITING
Conditions: Colo-rectal Cancer|Capecitabine|Cetuximab
Interventions: DRUG: mCapOX plus cetuximab|DRUG: mFOLFOX6 plus cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Blinatumomab in Combination With Salvage Autologous Stem Cell Transplantation for Patients With Refractory Multiple Myeloma
Status: TERMINATED
Conditions: Multiple Myeloma
Interventions: DRUG: Blinatumomab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Accelerometer for Quantification of Neurogenic Orthostatic Hypotension Symptoms
Status: RECRUITING
Conditions: Orthostatic; Hypotension, Neurogenic|Autonomic Failure|Pure Autonomic Failure|Multiple System Atrophy|Orthostatic; Hypotension, Parkinsonism
Interventions: DEVICE: Accelerometer|DRUG: placebo pill|DRUG: Midodrine or atomoxetine pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)
Status: NOT_YET_RECRUITING
Conditions: Stage I Kidney Wilms Tumor|Stage II Kidney Wilms Tumor|Stage III Kidney Wilms Tumor|Stage IV Kidney Wilms Tumor
Interventions: PROCEDURE: Bone Scan|DRUG: Carboplatin|PROCEDURE: Computed Tomography|DRUG: Cyclophosphamide|BIOLOGICAL: Dactinomycin|DRUG: Doxorubicin|DRUG: Etoposide|DRUG: Irinotecan|PROCEDURE: Magnetic Resonance Imaging|PROCEDURE: Nephrectomy|OTHER: Patient Observation|PROCEDURE: Positron Emission Tomography|PROCEDURE: Ultrasound Imaging|DRUG: Vincristine|PROCEDURE: X-Ray Imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Pacing Lead Design on Left Bundle Branch Pacing Outcomes
Status: RECRUITING
Conditions: Pacemaker DDD
Interventions: DEVICE: Fixed helix, lumenless pacing lead.|DEVICE: Extendable helix, stylet-driven pacing lead.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rivaroxaban 20 mg twice daily|DRUG: Rivaroxaban 20 mg once daily|DRUG: Profilnine SD|DRUG: Beriplex P/N|OTHER: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy With Pitavastatin in Coronary Artery Disease (REAL-CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DRUG: Pitavastatin 1 mg daily or 4 mg daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-Risk Populations in Kenya, Africa
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: FTC/TDF|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of the Auricular Acupunture of the Lower Limbs on the Equilibrium Response Evaluated by Static Stabilometry
Status: COMPLETED
Conditions: Balance, Postural
Interventions: DEVICE: Auricular acupunture|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Follow-up Study for Participants of Jointstem Investigator Initiated Trial by Arthroscopy
Status: NOT_YET_RECRUITING
Conditions: Degenerative Arthritis|Knee Arthritis
Interventions: DRUG: JOINTSTEM
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Inflammatory Burden in Hemodialysis vs. Peritoneal Dialysis Patients: the Role of Alpha-defensin
Status: UNKNOWN
Conditions: Kidney Failure|Inflammation
Interventions: DIAGNOSTIC_TEST: Blood Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Ocular Discomfort Assessment After Intravitreal Injections
Status: COMPLETED
Conditions: Macular Degeneration|Diabetic Retinopathy|Retinal Artery Occlusion|Myopia, Degenerative
Interventions: DRUG: Optive
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer|KRAS Activating Mutation
Interventions: DRUG: avutometinib (VS-6766)|DRUG: avutometinib (VS-6766) and Defactinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: COVID-19 iCura SARS-CoV-2 Ag OTC: Clinical Evaluation
Status: COMPLETED
Conditions: SARS-CoV-2 Infection|COVID-19
Interventions: DEVICE: iCura COVID-19 Antigen Rapid Home Test|DIAGNOSTIC_TEST: RT-PCR Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy of Faslodex in Treatment of SLE Clinical, Serologic, and Molecular Studies
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus
Interventions: DRUG: ICI 182,780 (Faslodex)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Hypofractionated Radiotherapy (Stereotactic) Versus Conventional Radiotherapy for Inoperable Early Stage I Non-small Cell Lung Cancer (NSCLC)
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: RADIATION: Hypofractionated radiotherapy (HypoRT)|RADIATION: Conventionally Fractionated Radiotherapy (ConRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold.
Status: NOT_YET_RECRUITING
Conditions: Radiodermatitis|Radiation Toxicity|Radiotherapy Side Effect
Interventions: DEVICE: Mepitel® film|OTHER: Flamigel®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects of Heart Rate Variability Biofeedback Training on Hematopoietic Cell Transplantation Patients
Status: COMPLETED
Conditions: Hematopoietic Stem Cell Transplantation|Bone Marrow Transplant|Heart Rate Variability|Autonomic Nervous System|Stress|Mood|Psychological Distress|Emotion Regulation|Communication Research|Narrative
Interventions: BEHAVIORAL: Baseline Surveys|BEHAVIORAL: Heart rate variability biofeedback|BEHAVIORAL: Heart rate variability waitlist and Digital storytelling Control intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa
Status: RECRUITING
Conditions: Meningococcal Immunisation|Healthy Volunteers
Interventions: BIOLOGICAL: Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine|BIOLOGICAL: Meningococcal (Groups A, C, Y and W 135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine|BIOLOGICAL: Oral bivalent types 1 and 3; Poliomyelitis Vaccine (OPV)|BIOLOGICAL: Pneumoccocal Vaccine|BIOLOGICAL: Measles, Mumps, and Rubella Vaccine live (MMR) - TRESIVAC®|BIOLOGICAL: DTwP-HepB-Hib-IPV vaccine|BIOLOGICAL: DTaP-IPV-Hib-HepB vaccine|BIOLOGICAL: Hepatitis A vaccine - HAPIBEV™|BIOLOGICAL: Rotavirus vaccine|BIOLOGICAL: Typhoid conjugate vaccine (TCV)|BIOLOGICAL: Measles vaccine - MeasBio®|BIOLOGICAL: Varicella vaccine live - VARIPED®|BIOLOGICAL: Varicella vaccine live - Onvara|BIOLOGICAL: Measles, Mumps, and Rubella Vaccine live (MMR) - OMZYTA®|BIOLOGICAL: Hepatitis A vaccine - Avaxim 80 U
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of Valproic Acid (VPA) vs Placebo to Shorten Time of Indwelling Pleural Catheter
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Placebo|DRUG: Valproic Acid (VPA)|BEHAVIORAL: Questionnaires|BEHAVIORAL: Pill Diary|BEHAVIORAL: Drainage Diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PRC-063 Adult Laboratory Classroom Study in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Status: COMPLETED
Conditions: ADHD
Interventions: DRUG: PRC-063 oral capsules|DRUG: Placebo oral capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Management in Gynaecological Carcinoma Surgery
Status: RECRUITING
Conditions: Gynaecological Carcinoma
Interventions: DRUG: ferric carboxymaltose|DRUG: tranexamic acid|DRUG: ferric carboxymaltose and tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Safety and Efficacy of FOLFIRI Plus Cetuximab or FOLFOX Plus Cetuximab as First-line Therapy in Subjects With KRAS Wild-type Metastatic Colorectal Cancer (APEC-Study)
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Cetuximab|DRUG: FOLFIRI|DRUG: FOLFOX
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerability, Safety and Pharmacokinetic Study Of Mianhuahua Flavonoids Tablets in Healthy Adult Subjects
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Mianhuahua Flavonoids Tablets|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Different Doses of Indacaterol
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Indacaterol|DRUG: Salmeterol|DRUG: Placebo to Indacaterol|DRUG: Placebo to Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Could Bulk Fill Glass Hybrid Restorative Materials Replace Composite Resins in Treating Permanent Teeth?
Status: COMPLETED
Conditions: Dental Restoration Failure of Marginal Integrity
Interventions: OTHER: Restoration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine and Sorafenib in Advanced Biliary Tract Cancer (GEMSO)
Status: COMPLETED
Conditions: Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Placebo|DRUG: Sorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Early Capsule Deployment to Current Standard of Care for Management of Gastrointestinal Bleeding
Status: COMPLETED
Conditions: Melena|Gastrointestinal Hemorrhage
Interventions: DEVICE: Early Video Capsule Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Randomized Comparison of MynxGrip Vascular Closure Device and Manual Compression for Closure After Femoral Access Angiography. The Closure Devices Used in Every Day Practice Study, CLOSE-UP III Trial
Status: COMPLETED
Conditions: Coronary Disease
Interventions: DEVICE: MynxGrip|OTHER: Manual compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety and Immune Response to Different Doses of a Cytomegalovirus Vaccine in Healthy Adults
Status: ACTIVE_NOT_RECRUITING
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: Pentamer (low)/gB(low)/Adjuvant vaccine|BIOLOGICAL: Pentamer (med)/gB(low)/Adjuvant vaccine|BIOLOGICAL: Pentamer (med)/gB(med)/Adjuvant vaccine|BIOLOGICAL: Pentamer (high)/gB(med)/Adjuvant vaccine|COMBINATION_PRODUCT: Placebo (saline)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy
Status: COMPLETED
Conditions: Diabetic Foot Ulcers
Interventions: DEVICE: V.A.C. Negative Pressure Wound Therapy System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Experimental Tobacco Marketplace in Regulating Flavored Tobacco Products in Menthol Cigarette Smokers
Status: TERMINATED
Conditions: Cigarette Smoking
Interventions: BEHAVIORAL: Smoking Cessation Intervention|OTHER: Functional Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Pilot Study to Improve Patient-Doctor Communication
Status: COMPLETED
Conditions: Chronic Disease|Hypertension|Hyperlipidemia|Diabetes Mellitus|Osteoarthritis|COPD|Cardiovascular Disease
Interventions: BEHAVIORAL: Patient Primer Tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Granheim COPD Study - Vitamin D and Strength Training
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Primary Care Patients With Depression for Internet-Based Social Support
Status: COMPLETED
Conditions: Depressive Disorder
Interventions: BEHAVIORAL: Simple Card|BEHAVIORAL: Patient Centered Brochure|BEHAVIORAL: Physician's endorsement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Whole Brain Irradiation in Primary Central Nervous System (CNS) Lymphoma (PCNSL)
Status: COMPLETED
Conditions: Central Nervous System Lymphoma
Interventions: DRUG: methotrexate|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Therapy for Temporomandibular Joint (TMJ) Closed Lock
Status: COMPLETED
Conditions: Temporomandibular Joint Disorders|Temporomandibular Joint Disc Displacement, Without Reduction
Interventions: PROCEDURE: physical therapy|PROCEDURE: control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Small Incision Technique Versus Upper Blepharoplasty in Upper Eyelid Medial Pad Fat Removal
Status: UNKNOWN
Conditions: Eyelid Diseases
Interventions: PROCEDURE: upper eyelid blepharoplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Belinostat When Used With Standard of Care Chemotherapy for Untreated Non-small Cell Lung Cancer
Status: TERMINATED
Conditions: Non-Small-Cell Lung Carcinoma
Interventions: DRUG: Belinostat, carboplatin, paclitaxel and bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation
Status: COMPLETED
Conditions: Cartilage Injury
Interventions: PROCEDURE: Autologous bone marrow aspirate will be harvested and concentrated to a bone marrow aspirate concentrate (BMAC) containing bone marrow derived mesenchymal stem cells and delivered to site of operation|PROCEDURE: Control group incision
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension
Status: NOT_YET_RECRUITING
Conditions: Liver Cirrhosis
Interventions: BIOLOGICAL: 20% Albumin|BIOLOGICAL: 5% Albumin|DRUG: Plasmalyte
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Opicapone at Steady State on Warfarin Pharmacokinetics
Status: COMPLETED
Conditions: Parkinson's Disease
Interventions: DRUG: BIA 9-1067|DRUG: Warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Sleep Quality on Hematopoietic Cell Transplant Patient Outcomes
Status: RECRUITING
Conditions: Sleep|Multiple Myeloma
Interventions: BEHAVIORAL: Mindfulness Awareness Practices for Insomnia|BEHAVIORAL: Sleep Health Information
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Profermin®: Prevention of Progression in Alcoholic Liver Disease by Modulating Dysbiotic Microbiota
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcoholic Liver Disease|Liver Cirrhosis, Alcoholic|Probiotics|Liver Fibrosis
Interventions: DIETARY_SUPPLEMENT: Profermin Plus, FSMP, probiotics|DIETARY_SUPPLEMENT: Fresubin, dietary supplement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: SteRilizing Eye SoLution to ImprovE Patient ComFort (RELIEF)
Status: RECRUITING
Conditions: Retinal Disease
Interventions: DRUG: IRX-101|DRUG: Providone-Iodine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer
Status: COMPLETED
Conditions: Renal Cell Carcinoma|Pharmacokinetics of AGS-16M8F
Interventions: DRUG: AGS-16M8F
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interoception and Body Scan
Status: COMPLETED
Conditions: Healthy
Interventions: BEHAVIORAL: Visceral body scan (VBS)|BEHAVIORAL: Somatosensory body scan (SBS)|BEHAVIORAL: External control meditation (ECM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries
Status: COMPLETED
Conditions: Ligament Injury
Interventions: DRUG: Acetaminophen|DRUG: Naproxen|DRUG: Celecoxib|OTHER: physiotherapy only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Impact of Choice on Colorectal Cancer Screening
Status: COMPLETED
Conditions: Colorectal Cancer|Colorectal Neoplasms|Health Screening
Interventions: BEHAVIORAL: Active FIT Choice|BEHAVIORAL: Active Colonoscopy Choice|BEHAVIORAL: Active Dual Choice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Symptom Monitoring in Hemodialysis
Status: RECRUITING
Conditions: End Stage Kidney Disease
Interventions: BEHAVIORAL: Symptom Monitoring on Renal Replacement Therapy - Hemodialysis (SMaRRT-HD)|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Three Single Oral Doses of Trazodone on the QTc Interval Duration in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Trazodone 20 mg|DRUG: Trazodone 60 mg|DRUG: Trazodone 140 mg|DRUG: Placebo|DRUG: Moxifloxacin 400mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Hepatitis B Virus Vaccination in HIV-positive Patients and Individuals at High Risk for HIV Infection
Status: UNKNOWN
Conditions: Viral Hepatitis B|Immunization; Infection|HIV Infections
Interventions: DRUG: Engerix-B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION