pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA
Status: COMPLETED
Conditions: Preterm Infant|BPD - Bronchopulmonary Dysplasia|Barotrauma
Interventions: OTHER: NAVA|OTHER: NIPPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Influence of Baseplate Adhesive on the Degree of Leakage
Status: COMPLETED
Conditions: Colostomy Stoma|Ileostomy Stoma
Interventions: DEVICE: Coloplast Test A|DEVICE: Coloplast Test B|DEVICE: Standard product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: HE3286|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Short-term Sugary Beverage Consumption on Glucose Control and Cardiovascular Disease Risk Factors
Status: COMPLETED
Conditions: Metabolic Syndrome
Interventions: DIETARY_SUPPLEMENT: Sugary beverage: Fruit juice|DIETARY_SUPPLEMENT: Sugary beverage: Soda|DIETARY_SUPPLEMENT: Control: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Safety Study of a Recombinant Protein-Free Manufactured Factor VIII (rAHF-PFM) in Previously Untreated Hemophilia A Patients
Status: COMPLETED
Conditions: Hemophilia A
Interventions: BIOLOGICAL: Recombinant Antihemophilic Factor Manufactured and Formulated without Added Human or Animal Proteins (rAHF-PFM)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ascending Dose Study of Investigational SARS-CoV-2 Vaccine ARCT-021 in Healthy Adult Subjects
Status: COMPLETED
Conditions: SARS-CoV-2
Interventions: BIOLOGICAL: ARCT-021 Dose 1|BIOLOGICAL: ARCT-021 Dose 2|BIOLOGICAL: ARCT-021 Dose 3|BIOLOGICAL: ARCT-021 Dose 4|BIOLOGICAL: ARCT-021 Dose Regimen 1|BIOLOGICAL: ARCT-021 Dose Regimen 2|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)
Status: COMPLETED
Conditions: Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome
Interventions: DRUG: Nivolumab|DRUG: Idarubicin|DRUG: Cytarabine|DRUG: Solu-medrol|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial Evaluating Hedonic vs Cash Incentives
Status: COMPLETED
Conditions: Physical Activity
Interventions: BEHAVIORAL: Hedonic Reward|BEHAVIORAL: Cash Reward|DEVICE: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects
Status: COMPLETED
Conditions: Vaccines, Pneumococcal Conjugate Vaccine
Interventions: BIOLOGICAL: 13-valent Pneumococcal Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Reconyl for Cough With/Without Sore Throat
Status: NOT_YET_RECRUITING
Conditions: Cough
Interventions: DRUG: Reconyl|DRUG: Placebo tablet of Reconyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of CCX282-B in Patients With Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: CCX282-B|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SHIVA02 - Evaluation of the Efficacy of Targeted Therapy Based on Tumor Molecular Profiling in Patients With Advanced Cancer Using Each Patient as Its Own Control (SHIVA02)
Status: ACTIVE_NOT_RECRUITING
Conditions: Cancer|Solid Tumor, Adult
Interventions: DIAGNOSTIC_TEST: research of druggable molecular alterations on tumor biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Multidisciplinary Low-Barrier and Mobile HIV Care to Improve Retention and Viral Suppression: Stakeholder-Engaged Design and Evaluation
Status: RECRUITING
Conditions: HIV
Interventions: OTHER: Active Referral|OTHER: Drop-In Multidisciplinary HIV Care|OTHER: Mobile HIV Care|OTHER: Staged Care|OTHER: Identify and prepare champions at referral sites|OTHER: Audit and feedback at referral sites|OTHER: Build a coalition among referral and clinical sites|OTHER: Assess for readiness and identify barriers|OTHER: Promote adaptability|OTHER: Develop a formal implementation blueprint|OTHER: Develop educational materials; conduct ongoing training|OTHER: Create a learning collaborative
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ranitidin Versus Omeprazole in Patients Taking Clopidogrel
Status: COMPLETED
Conditions: Coronary Artery Disease|Drug Interaction Potentiation
Interventions: DRUG: omeprazole|DRUG: Ranitidine|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: "Core Stabilization Exercises in Hearing Impaired Children"
Status: COMPLETED
Conditions: Hearing Disorders in Children|Core Stabilization|Respiratory Muscle Strength|Respiratory Functions|Postural Control
Interventions: OTHER: Core Stabilization Exercises|OTHER: No Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Dose Titration Study of MK-8892 in Participants With Pulmonary Hypertension and Left Heart Disease (MK-8892-007)
Status: TERMINATED
Conditions: Pulmonary Hypertension|Left Heart Disease
Interventions: DRUG: MK-8892
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate JCXH-211 as Monotherapy in Patients With Malignant Solid Tumors
Status: ACTIVE_NOT_RECRUITING
Conditions: Cutaneous Tumor|Malignant Solid Tumor
Interventions: DRUG: JCXH-211
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Short Term, High Dose Vitamin D Supplementation in Moderate to Severe COVID-19 Disease
Status: COMPLETED
Conditions: Covid19
Interventions: DRUG: cholecalciferol 6 lakh IU
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Status: NOT_YET_RECRUITING
Conditions: Hyperactivity in Children With Down Syndrome|Impulsivity in Children With Down Syndrome
Interventions: DRUG: Guanfacine Hydrochloride Immediate Release|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Breastfeeding Consultant Training in the Metvaverse Universe
Status: NOT_YET_RECRUITING
Conditions: Breast Feeding
Interventions: DEVICE: virtual reality training|OTHER: theoretical breastfeeding training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Phase 2 Clinical Trial to Evaluate Efficacy, Safety, and Tolerability of Navepegritide in Combination With Lonapegsomatropin in Children With Achondroplasia
Status: RECRUITING
Conditions: Achondroplasia
Interventions: DRUG: Combination of Navepegritide and Lonapegsomatropin administered as two separate s.c. injections
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Sevelamer Carbonate Powder to Sevelamer Hydrochloride Tablets in Patients With CKD on Hemodialysis
Status: COMPLETED
Conditions: Kidney Diseases|Chronic Renal Insufficiency|End-Stage Renal Disease
Interventions: DRUG: Sevelamer carbonate (Renvela®)|DRUG: Sevelamer hydrochloride (Renagel®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.
Status: TERMINATED
Conditions: Chronic Rhinosinusitis
Interventions: DRUG: Propofol and Remifentanyl|DRUG: Sevoflurane and Remifentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: INHIBITOR: Retrospective Study Of Patients With Renal Cell Carcinoma And Mantle Cell Lymphoma Treated With Temsirolimus
Status: COMPLETED
Conditions: Carcinoma, Renal Cell|Lymphoma, Mantle-Cell
Interventions: OTHER: Temsirolimus (Non-Interventional Study)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The ABEL Feasibility Study (Adherence, Better Health, Exercise and Life Satisfaction)
Status: RECRUITING
Conditions: Obesity
Interventions: BEHAVIORAL: High dosage in-person exercise coaching|BEHAVIORAL: Medium dosage in-person exercise coaching.|BEHAVIORAL: Low dosage in-person exercise coaching
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Retrospective Observational Study of Implant-supported Restorations With Dental Implants.
Status: ACTIVE_NOT_RECRUITING
Conditions: Oral Surgical Procedures
Interventions: PROCEDURE: Dental Implants installed in an grafted area (sinus lifting)|PROCEDURE: Dental Implants installed in an grafted area (ridge augmentation)|PROCEDURE: Dental Implants installed in an grafted area (extraction sites)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks
Status: COMPLETED
Conditions: Hereditary Angioedema (HAE)
Interventions: BIOLOGICAL: CINRYZE with rHuPH20
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: DAPAgliflozine to Attenuate Cardiac RemOdeling afTEr aCuTe myOcardial Infarction
Status: RECRUITING
Conditions: AMI|STEMI|NSTEMI|Left Ventricular Dysfunction
Interventions: DRUG: Dapagliflozin propanediol (FORXIGA™/FARXIGA™1)|DRUG: Placebo comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Role of Minoxidil in Alopecia Areata Transepidermal Drug Delivery of Minoxidil Via Either Fractional Carbon Dioxide Laser or Microneedling Versus Its Topical Nanoparticles Preparation for Treatment of Alopecia Areata
Status: NOT_YET_RECRUITING
Conditions: Alopecia Areata
Interventions: DEVICE: Fractional CO2 laser|DEVICE: Derma pen|DRUG: Niosome minoxidil|DRUG: Minoxidil Topical Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants ≥ 18 Years of Age With Asthma
Status: RECRUITING
Conditions: Asthma
Interventions: DRUG: Salbutamol HFA-134a|DRUG: Salbutamol HFA-152a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C)
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypercholesterolemia
Interventions: DRUG: inclisiran sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study Called EPI VITRAKVI to Compare Treatment Results in Patients With Infantile Fibrosarcoma (IFS), a Type of Connective Soft Tissue Cancer, Who Received a Treatment Called Larotrectinib From a Study Called SCOUT With Patient Data From an External Database
Status: COMPLETED
Conditions: Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene Fusion|Infantile Fibrosarcoma
Interventions: DRUG: Larotrectinib (Vitrakvi, BAY2757556)|DRUG: Standard of Care
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone
Status: UNKNOWN
Conditions: Surgical Site Infection
Interventions: DRUG: Hypochlorous acid|DRUG: Iodopovidone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Post-Market Study to Assess Outcomes of Patients Treated With AFX System Compared to Other EVAR Devices
Status: UNKNOWN
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: AFX EVAR AAA Graft System|DEVICE: FDA Approved EVAR AAA Graft Systems
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Motor Relearning Programme Versus Mirror Therapy on Balance and Gait in Chronic Stroke Patients
Status: NOT_YET_RECRUITING
Conditions: Stroke
Interventions: DIAGNOSTIC_TEST: Motor Relearning Program|DIAGNOSTIC_TEST: Mirror Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Positive Psychotherapy|BEHAVIORAL: Standard smoking cessation counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acceptability and Continuation Rate of Implanon in a Brazilian Public Sector
Status: COMPLETED
Conditions: Contraceptive Usage|Bleeding Due to Intrauterine Contraceptive Device
Interventions: DEVICE: copper-releasing intrauterine device|DEVICE: ENG-releasing implant|DEVICE: LNG-releasing intrauterine system|DEVICE: LNG-IUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Predict Antidepressant Responsiveness Using Pharmacogenomics
Status: UNKNOWN
Conditions: Depression|Depressive Symptoms
Interventions: DRUG: SSRI treated group|DRUG: non-SSRI treated group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Electrical Stimulation on Blood Circulation and Sensibility Tactil in Lymphadenectomy
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: PROCEDURE: high voltage electrical stimulation - axillary lymphadenectomy|PROCEDURE: High voltage electrical stimulation - ( healthy women )|DEVICE: Neurodyn High Volt Model (IBRAMED)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized Double-blind, Placebo-controlled Japanese Phase III Trial of ARQ 197 in Hepatocellular Carcinoma (HCC)
Status: COMPLETED
Conditions: Liver Cancer
Interventions: DRUG: ARQ197|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the PK of Multiple Oral Doses of Tegoprazan, Metronidazole, Tetracycline and Bismuth in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tegoprazan|DRUG: Metronidazole|DRUG: Tetracycline|DRUG: Bismuth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Academic-Community EPINET (AC-EPINET)
Status: RECRUITING
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorders|Major Depression With Psychotic Features|Bipolar Disorder With Psychotic Features
Interventions: OTHER: Coordinated Specialty Care (CSC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Prevent It 2.0/PRIORITY - An iCBT to Reduce the Risk of Committing Child Sexual Abuse
Status: RECRUITING
Conditions: Pedophilia
Interventions: OTHER: Prevent It 2.0|OTHER: Waitlist
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Clinical Study of KL-HIV-Tri01 in the Treatment of HIV Infected Subjects
Status: NOT_YET_RECRUITING
Conditions: HIV Infections
Interventions: DRUG: Low dose KL-HIV-Tri01|DRUG: Middle dose KL-HIV-Tri01|DRUG: High dose KL-HIV-Tri01
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Success Rate of Anterior Middle Superior Alveolar (AMSA) Nerve Block in Three Different Sites of Injection
Status: COMPLETED
Conditions: Anesthesia; Functional
Interventions: PROCEDURE: AMSA nerve block injectio
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: A Study to Investigate the Pharmacokinetics and Safety of Beclomethasone Dipropionate Administered by Breath-Actuated Inhaler and Metered-Dose Inhaler in Healthy Adults
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: Beclomethasone dipropionate BAI|DRUG: Beclomethasone dipropionate MDI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Atorvastatin Effect on Reduction of COPD Exacerbations
Status: RECRUITING
Conditions: Copd|COPD Exacerbation|Smoking|Gene Expression|Atorvastatin
Interventions: DRUG: Atorvastatin 40 Mg Oral Tablet|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cone Beam CT (CBCT) Arthrogram of the Ankle in Assessement of Osteochondral or Cartilage Lesions
Status: COMPLETED
Conditions: Cartilage Lesion|Osteochondral Lesion
Interventions: PROCEDURE: ArthroCT scan|PROCEDURE: CBCT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Hypertension and Cardiovascular Risk Associated With Obstructive Sleep Apnea in Adult in Guadeloupe (French West Indies)
Status: UNKNOWN
Conditions: Hypertension Arterial
Interventions: OTHER: Patient not SAHOS|OTHER: Patient SAHOS sailed by the ventilation in PPC and not sailed
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Study of the Combination of TACE With Apatinib in Patients With Hepatocellular Carcinoma
Status: UNKNOWN
Conditions: Hepatocellular Carcinoma
Interventions: PROCEDURE: TACE and Apatinib|PROCEDURE: TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: FS VH S/D 500 S-apr in Vascular Surgery
Status: COMPLETED
Conditions: Hemostasis in Participants Receiving Peripheral Vascular Expanded Polytetrafluoroethylene (ePTFE) Graft Prostheses
Interventions: BIOLOGICAL: Fibrin Sealant, Vapor Heated, Solvent/Detergent-treated with 500 IU/ml thrombin and synthetic aprotinin (FS VH S/D 500 s-apr)|OTHER: Surgical gauze pads
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility of Problem Solving Training Paired With Transcranial Magnetic Stimulation
Status: WITHDRAWN
Conditions: Stroke
Interventions: DEVICE: RepetiveTranscrainal Magnetic Stimulation (rTMS)|BEHAVIORAL: Problem-Solving Training (PST)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: 12 Week Open, Non-Comparative Switch Study Of Oral Ziprazidone In Previously Treated Schizophrenic Patients
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: ziprazidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vaginal Estrogen on Asymptomatic Microhematuria (AMH)
Status: TERMINATED
Conditions: Microscopic Hematuria
Interventions: DRUG: Premarin vaginal estrogen cream|DRUG: Placebo vaginal cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of the Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
Status: TERMINATED
Conditions: End Stage Renal Failure on Dialysis|Hyperplasia
Interventions: DEVICE: Graft, Vascular Wrap|DEVICE: Lifespan® ePTFE Vascular Graft Only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Influence of Thoracolumbar Proprioceptive Support in the Segmental Stabilization Training
Status: COMPLETED
Conditions: Transversus Abdominis Activation
Interventions: OTHER: Segmental trunk exercise associated with proprioception|OTHER: Segmental trunk exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: rTMS for Stimulant Use Disorders
Status: ACTIVE_NOT_RECRUITING
Conditions: Cocaine Use Disorder|Methamphetamine Abuse|Cocaine Dependence|Methamphetamine Dependence|Stimulant Use|Stimulant Abuse|Methamphetamine Use Disorder|Cocaine Abuse|Stimulant Use Disorder
Interventions: DEVICE: rTMS|DEVICE: Sham (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Phase 1, Open-label, Dose-escalation Trial With CD38-SADA:177 Lu-DOTA Drug Complex in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Status: NOT_YET_RECRUITING
Conditions: Non-hodgkin Lymphoma
Interventions: DRUG: CD38-SADA:177Lu-DOTA Complex
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Perifosine in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: perifosine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbetocin Versus Oxytocin for Prophylaxis Against Atonic Primary Post-partum Hemorrhage
Status: UNKNOWN
Conditions: Atonic Postpartum Hemorrhage|High Risk Pregnancy
Interventions: DRUG: Oxytocin|DRUG: Carbetocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Prospective Longitudinal 1-year Study of the Correlation Between Cognitive Functioning in Patients With Clinically Isolated Syndrome Suggestive of Multiple Sclerosis and Disconnection in the Brain Assessed by MRI
Status: COMPLETED
Conditions: Clinically Isolated Demyelinating Syndromes|Multiple Sclerosis|Cognitive Deficiencies|Brain MRI
Interventions: OTHER: Brain MRI - Clinical and cognitive evaluation|OTHER: Eye movement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Symmetric vs Asymmetric BLR Recession in Management of Basic IXT With Ocular Dominance
Status: UNKNOWN
Conditions: Intermittent Exotropia
Interventions: PROCEDURE: Bilateral Lateral Rectus Recession
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Health of IVF Versus IVM Children (FM-BABIES)
Status: COMPLETED
Conditions: Infertility|IVF|IVM
Interventions: DIAGNOSTIC_TEST: Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3|OTHER: Physical development and General Health|DIAGNOSTIC_TEST: Developmental Red flags
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Volumetric Analysis of Maxillary Sinus After Guided Lateral Sinus Lift Procedure
Status: COMPLETED
Conditions: Lateral Sinus Lifting|Dental Implant
Interventions: PROCEDURE: Lateral Maxillary Sinus Floor Elevation using surgical guide|PROCEDURE: Lateral Maxillary Sinus Floor Elevation without surgical guide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide, Thalidomide, and Lomustine (TTL) in Melanoma Patients
Status: COMPLETED
Conditions: Brain Neoplasms|Melanoma
Interventions: DRUG: Lomustine|DRUG: Temozolomide|DRUG: Thalidomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimal Timing of Dinoprostone Administration Prior to Office Hysteroscopy
Status: COMPLETED
Conditions: Dinoprostone Timing
Interventions: DRUG: long interval dinoprostone|DRUG: short interval dinoprostone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Treatment of Patients With Advanced Rectum Cancer With Capecitabine and Oxaliplatin Before, Under and After Radiation and With Adding Cetuximab to K-RAS Wild-type Patients
Status: UNKNOWN
Conditions: Rectum Cancer
Interventions: DRUG: cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of Oral Midazolam Plus Oral Ketamine for Sedation During Laceration Repair
Status: UNKNOWN
Conditions: Lacertaions
Interventions: DRUG: Ketamine|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Comparison of Vitamin's D2 and D3 in Stage 5 Chronic Kidney Disease Patients on Chronic Hemodialysis
Status: COMPLETED
Conditions: Chronic Kidney Disease
Interventions: DIETARY_SUPPLEMENT: Vitamin D3|DIETARY_SUPPLEMENT: Vitamin D2|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine
Status: UNKNOWN
Conditions: Diphtheria|Tetanus|Pertussis|Hepatitis B|Haemophilus Influenzae Type B
Interventions: BIOLOGICAL: Shan 5
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed Aggressive Non-Hodgkin's Lymphoma (NHL).
Status: RECRUITING
Conditions: Refractory Non-Hodgkin Lymphoma|Relapsed Non Hodgkin Lymphoma|Aggressive Non-Hodgkin Lymphoma
Interventions: DRUG: Mosunetuzumab|DRUG: Polatuzumab|BIOLOGICAL: CAR-T Cell Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Exploring Respiratory Health Outcomes From Sustained Use of Efficient Cookstoves
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Obstructive Pulmonary Disease|Asthma
Interventions: BEHAVIORAL: Improved Cookstoves
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimizing PrEP Uptake & Adherence Among Male Sex Workers (MSW) Using a 2-stage Randomization Design
Status: COMPLETED
Conditions: Prevention
Interventions: BEHAVIORAL: PrEPare for Work: Strength Based Case Management (Stage 1)|BEHAVIORAL: PrEPare for Work: Adherence Training and Counseling (Stage 2)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multicentric Trial of the Treatment of Huntington's Disease by Cysteamine (RP103)
Status: UNKNOWN
Conditions: Huntington's Disease
Interventions: DRUG: RP103|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients
Status: COMPLETED
Conditions: Gastrointestinal Cancer|Lung Cancer
Interventions: DRUG: Melatonin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Tele-Wellness Supported App for Family Child Care Home Providers and Families to Promote Health, Family Engagement, and School Readiness Amid COVID-19
Status: ENROLLING_BY_INVITATION
Conditions: Stress, Psychological|Child Behavior|Social Competence
Interventions: DEVICE: FamilyChildCare (provisional name of app)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Pilot Study of the Feasibility of Feeding Preterm Infants With Fresh Versus Frozen Mother's Own Breast Milk in the NICU
Status: COMPLETED
Conditions: Necrotizing Enterocolitis
Interventions: OTHER: Fresh Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: COVID-19 Booster Dose Reminder/Recall for Adolescents
Status: ACTIVE_NOT_RECRUITING
Conditions: COVID-19 Vaccines
Interventions: BEHAVIORAL: Reminder/Recall Sent Via Preferred Method of Communication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study Of JAK3 Inhibitor For The Prevention Of Acute Rejection In Kidney Transplant Patients
Status: WITHDRAWN
Conditions: Kidney Transplantation
Interventions: DRUG: Cyclosporine|DRUG: CP-690-,550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery
Status: RECRUITING
Conditions: Emergence Delirium|Strabismus|Pediatric ALL
Interventions: DRUG: Bridion 200 MG in 2 ML Injection|DRUG: Pyridostigmine Bromide 5 MG/ML
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Establishing and Eliminating Cue-drug Associations in Human Cocaine Addiction
Status: TERMINATED
Conditions: Cocaine Dependent Subjects
Interventions: DRUG: cocaine hydrochloride|DRUG: propranolol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma|Relapsed Hematologic Malignancy
Interventions: BEHAVIORAL: Digital Health Coaching Program|DEVICE: Fitbit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain
Status: COMPLETED
Conditions: Port-wine Stain
Interventions: DRUG: Hemoporfin PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Optimizing Patient Analgesic Experience During IVF
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: Lidocaine hydrochloride (HCl) 1% solution|DRUG: Sterile Normal Saline%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Psychological Well-being, Recovery and Sexuality After Total and Subtotal Hysterectomy
Status: COMPLETED
Conditions: Hysterectomy
Interventions: PROCEDURE: Total abdominal hysterectomy|PROCEDURE: Subtotal abdominal hysterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Functional Dairy Products Enriched With Dietary Fibers on Human Health and Gut Microbiota
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Test product|DIETARY_SUPPLEMENT: Control product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Fructans Supplementation on Parameters of Metabolic Syndrome
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Synergy 1|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Jump: MR Simulation For Radiation Therapy Master Protocol
Status: RECRUITING
Conditions: Prostate Cancer|Recurrent Adenocarcinoma|Liver Cancer|Head and Neck Cancer
Interventions: DEVICE: MRI Simulator|RADIATION: Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of the Administration of Fibrinogen in Liver Transplantation
Status: UNKNOWN
Conditions: Intraoperative Bleeding
Interventions: DRUG: Fibrinogen|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Radiotherapy With Double Checkpoint Blockade of Locally Advanced HNSCC
Status: COMPLETED
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma
Interventions: COMBINATION_PRODUCT: Durvalumab + Tremelimumab + RT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study In Women With Severe Diarrhea-Predominant Irritable Bowel Syndrome Having Failed Conventional Therapy
Status: COMPLETED
Conditions: Irritable Colon|Irritable Bowel Syndrome (IBS)
Interventions: DRUG: alosetron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Chronic Effects of Two Aerobic-training Models Performed in Water and on Dry Land in Patients With Type 2 Diabetes Mellitus (T2DM).
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: Aquatic exercise|OTHER: Land Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of an Aquatic Exercise Program in Patients With Chronic Low Back Pain
Status: RECRUITING
Conditions: Chronic Low-back Pain|Muscle Atrophy|Diagnostic Imaging|Exercise Therapy
Interventions: OTHER: Aquatic Therapy|OTHER: Standard Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early Phase Human Drug Trial to Investigate DYN101 in Participants 2 to 17 Years With Centronuclear Myopathies
Status: WITHDRAWN
Conditions: Centronuclear Myopathy
Interventions: DRUG: DYN101
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Carbon Fiber Transpedicular Screws in Treatment of Spinal Metastatic Disease
Status: RECRUITING
Conditions: Metastatic Spinal Cord Compression|Metastasis Spine
Interventions: PROCEDURE: Transpedicular spinal stabilization - carbon fibers-based implants|PROCEDURE: Transpedicular spinal stabilization - titanium implants|RADIATION: Stereotactic body radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Quadratus Lumborum Versus Transversus Abdominis Plane Nerve Block: A Comparison Study
Status: COMPLETED
Conditions: Anesthesia
Interventions: PROCEDURE: Control - Transversus Abdominus Plane Block|PROCEDURE: Quadratus Lumborum Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impacts of Stoppa and Total Extraperitoneal Inguinal Hernia Repair on the Lower Extremity Muscular Functions
Status: COMPLETED
Conditions: Hernia, Inguinal
Interventions: PROCEDURE: Stoppa inguinal hernia repair|PROCEDURE: Total extraperitoneal inguinal hernia repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Early and Low Dose Deferasirox (3.5 mg/kg FCT) to Suppress NTBI and LPI as Early Intervention to Prevent Tissue Iron Overload in Lower Risk MDS
Status: TERMINATED
Conditions: Myelodysplastic Syndromes
Interventions: DRUG: Deferasirox
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Validation of the Automated Evaluation of Gastrointestinal Symptoms (AEGIS) Platform
Status: COMPLETED
Conditions: Abdominal Pain|Deglutition Disorders|Fecal Incontinence|Nausea|Diarrhea|Constipation|Gastroesophageal Reflux
Interventions: OTHER: AEGIS (Automated Evaluation of Gastrointestinal Symptoms)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Randomized, Double-Blinded, Placebo-Controlled Trial of Laxatives for Children With Urge Syndrome
Status: COMPLETED
Conditions: Constipation
Interventions: DRUG: MiraLAX|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Oxaliplatin and Fluorouracil Plus Radiation Therapy in Treating Patients With Primary Esophageal or Stomach Cancer
Status: COMPLETED
Conditions: Esophageal Cancer
Interventions: DRUG: fluorouracil|DRUG: oxaliplatin|PROCEDURE: conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Internet-based Cognitive Behavioral Therapy for Adolescents With Sleep Problems- a Feasibility Trial
Status: COMPLETED
Conditions: Insomnia Disorder|Depressive Disorder|Anxiety Disorders|Pain, Chronic|Inflammation
Interventions: BEHAVIORAL: ICBT-I
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety，Tolerability and Pharmacokinetics Clinical Trial of JX11502MA Capsule
Status: UNKNOWN
Conditions: Schizophrenia
Interventions: DRUG: JX11502MA|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411
Status: TERMINATED
Conditions: Solid Tumor|Extensive-stage Small Cell Lung Cancer
Interventions: DRUG: BNT411|DRUG: Atezolizumab|DRUG: Carboplatin|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Can we Get Conscious Sedation by Combining Dexmedetomidine With Alfentanil?
Status: COMPLETED
Conditions: Procedural Sedation
Interventions: DRUG: Dexmedetomidine|DRUG: Alfentanil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anrotinib and Tirelizumab in First-line Treatment of RM-NPC
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: Anrotinib plus Tirelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Help Wanted: Evaluating a Prevention Intervention for People With Sexual Interest in Children
Status: RECRUITING
Conditions: Program Evaluation|Child Sexual Abuse|Perpetration of Child Sexual Abuse|Prevention Intervention
Interventions: OTHER: Help Wanted Prevention Intervention|OTHER: Waitlist Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Marginal Integrity and Clinical Evaluation of Polyetheretherketone (PEEK) Versus Lithium Disilicate (E-max) Endocrowns.
Status: UNKNOWN
Conditions: Endodontically Treated Teeth
Interventions: OTHER: PEEK|OTHER: Emax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant
Status: COMPLETED
Conditions: Schizophrenia|Schizo-affective Disorder
Interventions: DRUG: Risperidone Implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effects of Methylphenidate on Multiple Sclerosis
Status: UNKNOWN
Conditions: Fatigue in Multiple Sclerosis
Interventions: DRUG: Methelphenidate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Safety and Efficacy of Stribild Versus Atripla in Human Immunodeficiency Virus, Type 1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults
Status: COMPLETED
Conditions: HIV|HIV Infections
Interventions: DRUG: Stribild|DRUG: Atripla
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Dronabinol (Marinol®)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis
Status: COMPLETED
Conditions: Childhood Langerhans Cell Histiocytosis
Interventions: DRUG: leucovorin calcium|DRUG: methotrexate|DRUG: prednisolone|DRUG: vinblastine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluating the Effect of Digoxin and Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Placebo|DRUG: Digoxin 0.25 mg|DRUG: Ursodeoxycholic acid (UDCA) 500 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Three Knee Replacements
Status: UNKNOWN
Conditions: Osteoarthritis, Knee|Arthroplasty|Total Knee Replacement
Interventions: DEVICE: NexGen|DEVICE: Persona|DEVICE: PFC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Follow up Study of Group B Streptococcus Vaccine (GBS-NN/NN2 Vaccine) in Healthy Volunteers
Status: ENROLLING_BY_INVITATION
Conditions: Group B Streptococcus Infection
Interventions: BIOLOGICAL: GBS-NN/NN2
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Salivary miRNA Diagnostic Test for Autism
Status: COMPLETED
Conditions: Autism Spectrum Disorder|Developmental Delay
Interventions: OTHER: Salivary collection|OTHER: Vineland Adaptive Behavior Scale-III Assessment|OTHER: Medical history questionaire|OTHER: Autism Diagnostic Observation Schedule -2nd edition (ADOS-2)|OTHER: Mullen Scales of Early Learning
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p