pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Clinical and Microbiological Effects of Lactobacillus Rhamnosus in Treatment of Gingivitis
Status: UNKNOWN
Conditions: Gingivitis
Interventions: DIETARY_SUPPLEMENT: Treatment Gingivitis with Probiotic|OTHER: Treatment Gingivitis conventional
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With PAD
Status: RECRUITING
Conditions: Peripheral Arterial Disease|Peripheral Vascular Diseases
Interventions: DRUG: BEET IT - Concentrate Beet root juice|DRUG: BEET IT - Concentrate Beet root juice (nitrate depleted)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Gut Oxygenation and Laparoscopy
Status: COMPLETED
Conditions: Laparoscopy|Laparotomy|Oxygenation,|Ischemia-Reperfusion Injury
Interventions: PROCEDURE: Laparoscopy|PROCEDURE: left colectomy by laparotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Tourniquet Use in Total Knee Arthroplasty
Status: COMPLETED
Conditions: Blood Loss
Interventions: PROCEDURE: Short-duration tourniquet|PROCEDURE: Long-duration tourniquet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates
Status: COMPLETED
Conditions: Inhibition (Psychology)|Updating|General Knowledge|No Training
Interventions: BEHAVIORAL: Updating|BEHAVIORAL: Inhibition|BEHAVIORAL: General knowledge
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Can the Effects of High Flow Nasal Cannula Oxygenation on Postoperative Atelectasis be Evaluated With Lung Ultrasound
Status: ACTIVE_NOT_RECRUITING
Conditions: Postoperative Atelectasis|Bariatric Surgery Candidate|Ultrasound Therapy; Complications
Interventions: DEVICE: High flow nasal cannula oxygen is applied|DEVICE: High flow nasal cannula oxygen is not applied
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SCREENING
Clinical trial: Investigational Multi-purpose Contact Lens Care Solution.
Status: COMPLETED
Conditions: Contact Lens Wear
Interventions: DEVICE: Vistakon Investigational Multi-Purpose Solution I|DEVICE: ReNu MultiPlus Multi-Purpose Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Increased Perioperative Communication Program in Knee Arthroplasty
Status: NOT_YET_RECRUITING
Conditions: Knee Arthroplasty|Postoperative Complications
Interventions: OTHER: increased perioperative communication program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Metronidazole for Pulmonary Tuberculosis (South Korea)
Status: COMPLETED
Conditions: Tuberculosis|Multi-Drug Resistant Tuberculosis
Interventions: DRUG: Metronidazole|PROCEDURE: Blood Draw|PROCEDURE: CT Scan|PROCEDURE: PET Scan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder (ADHD)
Status: ENROLLING_BY_INVITATION
Conditions: Attention Deficit/Hyperactivity Disorder
Interventions: DRUG: Centanafadine Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Drug-Drug Interaction Study Between Quinine Sulfate and Rosiglitazone
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Rosiglitazone 4 mg Tablets|DRUG: Rosiglitazone 4 mg Tablets|DRUG: Quinine Sulfate 324 mg Capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Randomized Study of Failed SCS Trials Comparing Outcomes Using the Observational Mechanical Gateway (OMG) Connector
Status: COMPLETED
Conditions: Chronic Pain
Interventions: DEVICE: Non Boston Scientific SCS Trial Therapy|DEVICE: BSC approved SCS Trial Therapy w/ OMG
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Probiotic Supplementation on Cognition and Related Health Outcomes Among Video Gamers
Status: COMPLETED
Conditions: Stress|Attention Disturbances
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Ticagrelor Versus Clopidogrel in Ischemic Stroke
Status: COMPLETED
Conditions: Ischemic Stroke
Interventions: DRUG: Ticagrelor 90 MG Oral Tablet|DRUG: Clopidogrel tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Minimally Invasive Non Surgical Therapy Versus Conventional Scaling and Root Planing for Treatment of Periodontitis
Status: COMPLETED
Conditions: Periodontal Diseases
Interventions: PROCEDURE: MINST|PROCEDURE: Conventional SRP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects From 6 Through 17 Years of Age With Moderate to Severe Plaque Psoriasis
Status: ACTIVE_NOT_RECRUITING
Conditions: Psoriasis
Interventions: DRUG: Apremilast
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Context Effects in Exercise Therapy for Knee and/or Hip Pain
Status: COMPLETED
Conditions: Joint Pain|Knee Pain|Hip Pain|Osteoarthritis, Knee|Osteoarthritis, Hip
Interventions: OTHER: Contextually enhanced physical surroundings of exercise|OTHER: Neuromuscular exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Changes in Everydaylife Activity of Children With CP During HABIT-ILE
Status: COMPLETED
Conditions: Cerebral Palsy
Interventions: OTHER: HABIT-ILE|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass
Status: COMPLETED
Conditions: Congenital Heart Disease|Disorder of Fetus or Newborn
Interventions: DRUG: Methylprednisolone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers
Status: COMPLETED
Conditions: Nicotine Dependence
Interventions: DRUG: Bupropion (Zyban)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Micropulse 577nm Laser vs Traditional Laser Treatment in Central Serous Chorioretinopathy
Status: COMPLETED
Conditions: Central Serous Choroidopathy
Interventions: DEVICE: 577-MPL|DEVICE: TLT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Initial Study of AZD7325 in Adults With Fragile X Syndrome
Status: COMPLETED
Conditions: Fragile X Syndrome
Interventions: DRUG: AZD7325 (High-Dose)|DRUG: AZD7325 (Low-Dose)|DRUG: Placebo oral capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Rehabilitation on the Recovery of Patients Post Right Stroke With Unilateral Spatial Neglect
Status: UNKNOWN
Conditions: Cerebrovascular Accident|Perceptual Disorders
Interventions: PROCEDURE: The phasic alerting treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Blood Flow Restriction Training on Lower Limb Motor Function in Stroke Patients With Hemiplegia
Status: WITHDRAWN
Conditions: Hemiplegia and/or Hemiparesis Following Stroke
Interventions: BEHAVIORAL: Blood flow restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of Famitinib in Patients With Advanced or Metastatic Gastroenteropancreatic Neuroendocrine Tumor
Status: TERMINATED
Conditions: Gastroenteropancreatic Neuroendocrine Tumor
Interventions: DRUG: Famitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Between Air-Q Intubating Laryngeal Airway and Ambu® AuraGain™
Status: COMPLETED
Conditions: General Anaesthesia
Interventions: DEVICE: Ambu Aura Gain supraglottic airway|DEVICE: Air-Q supraglottic airway
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Pilot Study in Healthy Men to Characterize the Uptake of Buprenorphine Into and Its Elimination From the Body After Topical Application of Two New Forms of a Skin Patch in Comparison to a Reference Patch
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Test Product T1: Buprenorphine patch (9 mg)|DRUG: Test Product T2: Buprenorphine patch (3.8 mg)|DRUG: Reference Product R: Transtec patch (20 mg)|DRUG: Matching placebo patch to T1|DRUG: Matching placebo patch to T2|DRUG: Matching placebo patch to R
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dextrose Prolotherapy on Isokinetic Power in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Knee Osteoarthritis|Dextrose Prolotherapy Injection|Physical Therapy
Interventions: DRUG: Dextrose prolotherapy injection|COMBINATION_PRODUCT: conventional physical therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)
Status: RECRUITING
Conditions: Atherosclerotic Cardiovascular Disease (ASCVD)|Elevated Lp(a)
Interventions: DRUG: Lepodisiran Sodium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEX
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Casodex 150mg|PROCEDURE: Radiotherapy|PROCEDURE: Haematology
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Stimulation for the Acute Treatment of Cluster Headache
Status: COMPLETED
Conditions: Chronic Cluster Headache
Interventions: DEVICE: Stimulation (Sub-perception)|DEVICE: Stimulation (Full)|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bufei Yishen Granule for Reducing Acute Exacerbation in GOLD Stage 3 or 4 COPD
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: DRUG: Bufei Yishen granule|DRUG: Placebo Bufei Yishen granule|DRUG: Tiotropium Bromide Powder for Inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Positron Emission Tomography (PET) With [89]Zr-Df-IAb2M in Patients With High-risk Prostate Cancer
Status: WITHDRAWN
Conditions: Prostate Cancer
Interventions: RADIATION: [89Zr]Df-IAB2M
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Blood Flow Restriction Training for Treatment of Chronic Patellar Tendinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Patellar Tendinopathy|Jumper's Knee
Interventions: OTHER: Heavy-Slow Resistance training|OTHER: Low-Load Blood Flow Restriction training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Conversion to Prograf® (Tacrolimus) to the Continuation of Cyclosporine in Patients at Risk for Chronic Renal Allograft Failure
Status: COMPLETED
Conditions: Graft Rejection|Kidney Transplantation
Interventions: DRUG: tacrolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of the Drug I131-Omburtamab in People With Desmoplastic Small Round Cell Tumors and Other Solid Tumors in the Peritoneum
Status: RECRUITING
Conditions: Desmoplastic Small Round Cell Tumor|Peritoneal Cancer|Peritoneal Carcinoma
Interventions: DRUG: 131 I-omburtamab|RADIATION: WAP-IMRT
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Gastric or Duodenal Nutrient Infusion on Food Intake, Obesity and Comorbidities in Obese Individuals
Status: COMPLETED
Conditions: Obesity
Interventions: OTHER: Infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin
Status: COMPLETED
Conditions: Alzheimer's Disease|Huntington's Disease
Interventions: DRUG: Dimebon IR|DRUG: Dimebon Transdermal|DRUG: Dimebon Transdermal|DRUG: Dimebon IR|DRUG: Dimebon Transdermal
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Safety and Efficiency of γδ T Cell Against Hematological Malignancies After Allo-HSCT
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Myelodysplastic Syndromes|Lymphoma
Interventions: BIOLOGICAL: Ex-vivo expanded γδ T cell infusion
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of Minimally Invasive Ponto Surgical Technique (MIPS) - Design Iteration
Status: COMPLETED
Conditions: Bone Conduction Deafness|Unilateral Deafness|Middle Ear Deafness|Mixed Hearing Loss
Interventions: DEVICE: Minimally Invasive Ponto Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: MR Imaging Study Using the Northern Alberta Linac-MR (Northern LIGHTs - 1)
Status: RECRUITING
Conditions: Cancer
Interventions: DEVICE: MR scan with the Alberta linac-MR P3 system
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
Status: COMPLETED
Conditions: Alcohol-Related Disorders|Marijuana Abuse|Substance-Related Disorders
Interventions: DRUG: Fluoxetine + outpatient cognitive behavioral therapy|DRUG: fluoxetine|DRUG: placebo + CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate the Efficacy and Safety of MS-553 in CLL/SLL
Status: TERMINATED
Conditions: Lymphocytic Leukemia|Small Lymphocytic Lymphoma
Interventions: DRUG: MS-553
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Continuous Infusion and Intermittent Bolus Adductor Canal Block for Total Knee Arthroplasty
Status: RECRUITING
Conditions: Arthroplasty, Replacement, Knee|Adductor Canal Block
Interventions: DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Ibuprofen to Treat Acute Traumatic Spinal Cord Injury
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DRUG: Dolormin® extra (Ibuprofen)|DRUG: Dolormin® extra (Ibuprofen)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Different Face Masks on Maximal and Submaximal Performance Testing During COVID-19
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: No Mask|OTHER: Surgical Mask|OTHER: N95 Mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Metabolic Profiling of Hematopoietic Stem Cells in Clonal Hematopoiesis (CHIP)
Status: RECRUITING
Conditions: Osteoporosis|Osteoarthritis, Hip|Hip Fractures|Clonal Hematopoiesis of Indeterminate Potential|Aging
Interventions: OTHER: Blood and bone marrow cell collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Self-sampling for Non-attenders to Cervical Cancer Screening
Status: RECRUITING
Conditions: Cervical Cancer|Cervical Dysplasia|Human Papillomavirus Infection
Interventions: DIAGNOSTIC_TEST: Self-sampling by Evalyn Brush|DIAGNOSTIC_TEST: Self sampling by Evalyn Brush home or in GP´s clinic
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Effects of Tea Catechin Extracts on Oxidative Damage
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: catechin extracts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assessment of Safety and Efficacy of ThisCART19A in Adult Patients With B Cell Malignancies After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy
Status: NOT_YET_RECRUITING
Conditions: Allogeneic, CAR-T, Protein Sequestration, Non-gene Edited
Interventions: DRUG: ThisCART19A|DRUG: Fludarabine Pill|DRUG: Cyclophosphamide|DRUG: VP-16 Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IV Glucose for Dehydration Treatment
Status: COMPLETED
Conditions: Dehydration
Interventions: DRUG: 5% Dextrose (D5) in Normal Saline (NS)|DRUG: Normal Saline (NS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of STSP-0902 in Healthy Subjects
Status: RECRUITING
Conditions: Oligozoospermia|Asthenozoospermia
Interventions: DRUG: STSP-0902 injection|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy in Treating Patients With Recurrent, Refractory, or Metastatic Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Colorectal Cancer|Esophageal Cancer|Extrahepatic Bile Duct Cancer|Gallbladder Cancer|Liver Cancer|Lung Cancer|Lymphoma|Pancreatic Cancer|Small Intestine Cancer|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: fluorouracil|DRUG: gemcitabine hydrochloride|DRUG: leucovorin calcium
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Translation of the DE-PLAN Program for the Primary Prevention of Type 2 Diabetes in Routine Primary Care
Status: COMPLETED
Conditions: Prediabetic State
Interventions: BEHAVIORAL: DE-PLAN|BEHAVIORAL: Control group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Tumor Bed Dose Delivery Using A Breast Specific Radiosurgery Device, The Gammapod: (A Clinical Feasibility Study)
Status: UNKNOWN
Conditions: Breast Neoplasms
Interventions: DEVICE: GammaPod Tumour Bed Boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single and Multiple Ascending Doses of MEDI6570 in Subjects With Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Atherosclerosis|Cardiovascular Disease
Interventions: BIOLOGICAL: MEDI6570|BIOLOGICAL: Placebo|BIOLOGICAL: Part B Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Efficacy and Safety During Endoscopic Submucosal Dissection Between Dexmedetomidine-remifentanil and Propofol-remifentanil
Status: COMPLETED
Conditions: Early Gastric Cancer Patients Who Were Scheduled for Endoscopic Submucosal Dissection
Interventions: DRUG: Dexmedetomidine - remifentanil group|DRUG: Propofol - remifentanil group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2)
Status: UNKNOWN
Conditions: Malaria|Burkina Faso
Interventions: DRUG: Artemether-lumefantrine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: PTSD
Interventions: BEHAVIORAL: Cognitive Processing Therapy|DRUG: Stellate Ganglion Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fibrin Sealant in Bilateral Simultaneous Total Knee Arthroplasty With Focus on Blood Loss, Pain, Swelling and Strength
Status: COMPLETED
Conditions: Blood Loss
Interventions: DRUG: Fibrin sealant|DRUG: Saline water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cell Therapy to Improve Burn Wound Healing
Status: COMPLETED
Conditions: Skin Burn Degree Second
Interventions: BIOLOGICAL: Allogeneic (MSC's) Application to the Burn Wounds
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Single Centre Study to Analyze Cataract Surgery Following Femtosecond Laser-Assisted and Manual Cataract Surgery
Status: COMPLETED
Conditions: Cataract
Interventions: DEVICE: Laser-assisted cataract surgery|DEVICE: Manually performed cataract surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Electrical Stimulation for Critically Ill Covid-19 Patients
Status: COMPLETED
Conditions: Covid19|Muscle Atrophy|Muscle Weakness
Interventions: DEVICE: Electrical Stimulation|DEVICE: Electrical Stimulation - Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial of Adjuvant Chemotherapy in Breast Cancer Patients With Pathological Partial Response and Complete Response to Neoadjuvant Chemotherapy
Status: UNKNOWN
Conditions: Invasive Ductal Breast Cancer|Tubular Breast Cancer|Mucinous Breast Cancer|Inflammatory Breast Cancer
Interventions: DRUG: Paclitaxel|DRUG: Cisplatin|DRUG: Epirubicin|DRUG: Cyclophosphamide|DRUG: 5-fluoruracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Benefit of PECS Blocks for Biceps Tenodesis Shoulder Surgery
Status: COMPLETED
Conditions: Biceps Tendonitis
Interventions: PROCEDURE: PECS "Pectoralis" 1 and 2 Blocks|PROCEDURE: Interscalene Block|PROCEDURE: Sham Block|DRUG: Solution for Injection in Interscalene Block|DRUG: Solution for Injection in Sham Block|DRUG: Solution for Injection PECS Blocks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Continuous Subcutaneous Insulin Infusion of a Liquid Formulation of BioChaperone Insulin Lispro in Comparison to Humalog®
Status: COMPLETED
Conditions: Type 1 Diabetes Mellitus
Interventions: DRUG: BioChaperone insulin lispro|DRUG: Humalog®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunology of Ebola Vaccine
Status: RECRUITING
Conditions: Ebola Virus Disease
Interventions: BIOLOGICAL: Recombinant Vesicular Stomatitis Vaccine for Ebola (rVSV∆G-ZEBOV-GP)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Brain MRI for Knee OA
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Central Sensitisation|Knee Osteoarthritis
Interventions: BEHAVIORAL: Cold Pressor Gel Test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Spontaneous Atrio Ventricular Conduction Preservation
Status: COMPLETED
Conditions: Sinus Node Dysfunction|Bradycardia-Tachycardia Syndrome|Paroxysmal Atrioventricular Block
Interventions: DEVICE: Symphony D 2450|DEVICE: Symphony DR 2550
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Anxiety After Stroke (TASK)
Status: COMPLETED
Conditions: Anxiety Disorders|Stroke|Transient Ischemic Attack
Interventions: BEHAVIORAL: TASK-CBT|BEHAVIORAL: TASK-Relax
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Acutely Agitated Patients With Asenapine Sublingual Tablets
Status: COMPLETED
Conditions: Agitation
Interventions: DRUG: Asenapine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Early and Late Removal of the Urinary Catheter After Rectum Resection
Status: UNKNOWN
Conditions: Colorectal Surgery|Rectal Cancer|Urinary Retention Postoperative
Interventions: PROCEDURE: Procedure: Early removal group|PROCEDURE: Procedure: Late removal group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Two Formulations of ELAPR Compared to Restylane® Vital Light Following Repeat Implants in the Upper Arm Dermis
Status: COMPLETED
Conditions: Intrinsic Aging of Skin
Interventions: DEVICE: Tropoelastin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Cadonilimab Plus TACE in Patients With Intermediate-stage Unresectable Hepatocellular Carcinoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Cadonilimab+TACE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of a Chemotherapy With Docetaxel-Prednisone for Castration-resistant Metastatic Prostate Cancer Elderly Patients
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Docetaxel every 3 weeks + Prednisone|DRUG: Docetaxel weekly+ Prednisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Pharmacology Study to Evaluate the Total Systemic Exposure and the Lung Availability of CHF 5993 in Healthy Volunteers
Status: COMPLETED
Conditions: COPD
Interventions: DRUG: CHF 5993 100/6/12,5 pMDI|DRUG: CHF 5993 100/6/12,5 DPI Test 1|DRUG: CHF 5993 100/6/12,5 DPI Test 2|DRUG: CHF 5993 100/6/12,5 pMDI replicate|DRUG: CHF 5993 100/6/12,5 pMDI with Valved Holding Chamber
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Identify and Characterise Bacteria Causing Chronic Cough Among Children in United Kingdom
Status: TERMINATED
Conditions: Infections, Respiratory Tract
Interventions: PROCEDURE: Cough swab|PROCEDURE: Oropharyngeal swab|PROCEDURE: Nasopharyngeal swabs|PROCEDURE: Blood sample|PROCEDURE: Bronchoscopy/ bronchoalveolar lavage samples|OTHER: Data collection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Measuring Bladder Volumes Scanning in the ICU
Status: COMPLETED
Conditions: Urinary Retention|Acute Kidney Injury
Interventions: OTHER: Bladder Volume Measurement bladder scanner RN|OTHER: Bladder Volume Measurement Ultrasound APRN|OTHER: Bladder Volume Measurement bladder scanner APRN|OTHER: Bladder Volume Measurement Ultrasound MD|OTHER: Intermittent Straight Catheterization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Double-blind Placebo-controlled Study to Evaluate Larazotide Acetate for the Treatment of Celiac Disease
Status: COMPLETED
Conditions: Celiac Disease
Interventions: DRUG: Larazotide Acetate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: BioFreedom QCA Study in CAD Patients
Status: UNKNOWN
Conditions: Coronary Artery Disease|Cardiac Death|Myocardial Infarction
Interventions: DEVICE: BioFreedom™ CoCr Biolimus A9™ stent|DEVICE: BioFreedom™ SS Biolimus A9™ stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treadmill Training With Kinesiotaping Affects Balance and Gait in Chronic Stroke Patients
Status: RECRUITING
Conditions: Stroke
Interventions: DEVICE: treadmill training with KT group (TTKT group)|DEVICE: treadmill training without KT group (TT group)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.
Status: COMPLETED
Conditions: Pulmonary Arterial Hypertension, Children
Interventions: DRUG: Sildenafil citrate|DRUG: Sildenafil citrate|DRUG: Placebo|DRUG: Sildenafil citrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis
Status: COMPLETED
Conditions: Anemia|Peritoneal Dialysis
Interventions: DIETARY_SUPPLEMENT: Vitamin C|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Graft-first Versus Fistula-first in Older Patients With End-stage Kidney Disease
Status: COMPLETED
Conditions: Kidney Diseases
Interventions: PROCEDURE: Upper arm arteriovenous graft surgery|PROCEDURE: Upper arm arteriovenous fistula surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer
Status: RECRUITING
Conditions: Cervical Esophagus Adenocarcinoma|Clinical Stage II Esophageal Adenocarcinoma AJCC v8|Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8|Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8|Clinical Stage III Esophageal Adenocarcinoma AJCC v8|Gastroesophageal Junction Adenocarcinoma|Pathologic Stage II Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8|Pathologic Stage III Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8|Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8|Thoracic Esophagus Adenocarcinoma
Interventions: DRUG: Capecitabine|DRUG: Carboplatin|DRUG: Docetaxel|DRUG: Fluorouracil|OTHER: Hafnium Oxide-containing Nanoparticles NBTXR3|RADIATION: Intensity-Modulated Radiation Therapy|DRUG: Leucovorin|DRUG: Oxaliplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spondyloarthritis Inception Cohort of Southern Denmark
Status: ENROLLING_BY_INVITATION
Conditions: Axial Spondyloarthritis|Back Pain
Interventions: OTHER: Rehabilitation intervention|OTHER: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)
Status: UNKNOWN
Conditions: Adrenergic Beta-Antagonists|Stable Angina Pectoris|Medication Adherence|Mobile Applications
Interventions: DEVICE: Patient support tool
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of a Synbiotics-containing Starter Formula on Infant Growth
Status: COMPLETED
Conditions: Infant Nutrition
Interventions: OTHER: Standard infant formula with prebiotics|OTHER: Infant formula with synbiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Human Behavioral Pharmacology Laboratory (HBPL) Study of Varenicline's Impact on Cocaine and Alcohol Craving
Status: COMPLETED
Conditions: Alcohol Dependence|Cocaine Dependence
Interventions: DRUG: Varenicline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: B-Left HF: Biventricular Versus Left Univentricular Pacing With Implantable Cardiac Defibrillator (ICD) Back-Up in Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure|Ventricular Dysfunction|Heart Diseases
Interventions: DEVICE: Cardiac Resynchronization Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8
Status: RECRUITING
Conditions: Periapical Periodontitis
Interventions: DRUG: Simvastatin Powder|DRUG: Calcium Hydroxide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Bioequivalence Study of Loxoprofen Sodium Patches in Healthy Volunteers
Status: NOT_YET_RECRUITING
Conditions: Osteoarthritis|Muscle Pain|Swelling Muscle
Interventions: DRUG: Loxoprofen Sodium Patches(reference product)|DRUG: Loxoprofen Sodium Patches(test product )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Happy Family Kitchen Movement Project
Status: COMPLETED
Conditions: Family Health, Happiness and Harmony|Physical Health|Psychosocial Health|Family Communication|Healthy Lifestyle
Interventions: BEHAVIORAL: Physical Exercise (PE)|BEHAVIORAL: Healthy Diet (HD)|OTHER: Wait-list Control (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Study of 3-Dimensional Conformal Radiotherapy (3D-CRT) Versus Intensity Modulated Radiotherapy (IMRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
Status: UNKNOWN
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: RADIATION: 3 Dimensional Radiation Therapy|RADIATION: Intensity Modulated Radiation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose Tapering Study of Adalimumab in Psoriasis
Status: TERMINATED
Conditions: Psoriasis Vulgaris
Interventions: PROCEDURE: Venapuncture|PROCEDURE: Dried blood spot|DRUG: Dose reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Timolol 0.5% in Atrophic Acne Scar
Status: NOT_YET_RECRUITING
Conditions: Acne Scars - Mixed Atrophic and Hypertrophic
Interventions: PROCEDURE: microneedling|PROCEDURE: microneedling with topical timolol 0.5%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Psychoeducational Simulation Game for Adults in Stepfamilies
Status: COMPLETED
Conditions: Internet-Based Intervention|Remarriage
Interventions: OTHER: Psychoeducational Game
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of an Exercise Rehabilitation Program on Symptoms in Hemodialysis
Status: COMPLETED
Conditions: End-stage Renal Disease|Renal Failure Chronic Requiring Hemodialysis
Interventions: BEHAVIORAL: Exercise Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Functional Outcome and MRI of Muscle Damage Following Nailing Procedure in Femur (Thigh) Fractures Using Different Entry Points
Status: COMPLETED
Conditions: Femoral Shaft Fracture
Interventions: DEVICE: Femoral Nailing with Different Entry Points
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Prilinostat Mesylate for Injection in the Treatment of Relapsed or Refractory B Cell-related Tumor-predominant
Status: COMPLETED
Conditions: Diffuse Large B Cell Lymphoma，DLBCL
Interventions: DRUG: Prilinostat Mesylate 1.2mg/m2|DRUG: Prilinostat Mesylate 2.4mg/m2|DRUG: Prilinostat Mesylate 4.0mg/m2|DRUG: Prilinostat Mesylate 6.0mg/m2|DRUG: Prilinostat Mesylate 8.4mg/m2|DRUG: Prilinostat Mesylate 11.2mg/m2|DRUG: Prilinostat Mesylate 15mg/m2
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of HLX22 in Combanition With Trastuzumab and Chemotherapy Versus Placebo in Combination With Trastuzumab and Chemotherapy for Treatment of Locally Advanced or Metastatic Gastric Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Gastric Cancer
Interventions: DRUG: HLX22|DRUG: Placebo|DRUG: Trastuzumab|DRUG: Oxaliplatin|DRUG: Capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 3D Holographic Guidance, Navigation, and Control for Endovascular Aortic Repair
Status: RECRUITING
Conditions: Abdominal Aortic Aneurysm
Interventions: DEVICE: 3D Holographic Guidance, Navigation, and Control (3D GN&C)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients
Status: COMPLETED
Conditions: Acute Lung Injury
Interventions: DRUG: Calfactant|OTHER: Air placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Does Dairy Benefit Bone & Body Composition in Overweight Girls Undergoing a Weight Management Program?
Status: COMPLETED
Conditions: Overweight|Obesity|Children
Interventions: BEHAVIORAL: I.D.E.A.L. for Adolescents Study - Higher Dairy|BEHAVIORAL: I.D.E.A.L. for Adolescents Study - Lower Dairy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects
Status: UNKNOWN
Conditions: Intrabony Periodontal Defect
Interventions: PROCEDURE: Injectable platelet rich fibrin combined with DFDBA|PROCEDURE: Demineralized Freeze Dried Bone Allograft
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopaminergic Mechanism of Memory Impairment in Parkinson's Disease
Status: UNKNOWN
Conditions: Parkinson Disease|Memory Impairment
Interventions: DRUG: Madopar monotherapy|DRUG: senfrol monotherapy|DRUG: placebo monotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: An Extension Study to Evaluate the Long-Term Safety and Tolerability of UTTR1147A in Participants With Moderate to Severe Ulcerative Colitis or Crohn's Disease
Status: TERMINATED
Conditions: Ulcerative Colitis|Crohn's Disease
Interventions: DRUG: UTTR1147A
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Contributions of a Paramedical Approach in the Prevention and Treatment of Side Effects Associated With Radical Prostatectomy
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostatic Neoplasms
Interventions: BEHAVIORAL: Oncosexology program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Quantification of the Antidyskinetic Effect of Amantadine and Topiramate in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: DRUG: Amantadine 300 mg|DRUG: Topiramate|DRUG: Sugar Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating the Efficacy of Nifedipine GITS - Telmisartan Combination in Blood Pressure Control.
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Nifidipine|DRUG: Telmisartan|DRUG: Nifedipine/Telmisartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Lancet Blood Sampling for Radioiodine Dosimetry in Thyroid Cancer
Status: COMPLETED
Conditions: Cancer of the Thyroid|Cancer of Thyroid|Thyroid Cancer|Thyroid Carcinoma
Interventions: OTHER: Lancet blood sampling|OTHER: Standard intravenous blood sampling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Status: RECRUITING
Conditions: Depressive Disorder, Major|Bipolar Disorder|Post Traumatic Stress Disorder
Interventions: DRUG: Ketamine|DRUG: Perampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney Transplantation
Status: COMPLETED
Conditions: Adult Primary Kidney Transplantation
Interventions: DRUG: Tacrolimus/Sirolimus|DRUG: Tacrolimus/MMF|DRUG: Neoral/Sirolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Efficacy and Safety of Multiple Roxadustat Dosing Regimens for the Treatment of Anemia in Dialysis Participants With Chronic Kidney Disease
Status: COMPLETED
Conditions: CKD Anemia in Dialysis Participants
Interventions: DRUG: Roxadustat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT