pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Fibersol-2 Clinical Trials Related to Appetite
Status: COMPLETED
Conditions: Lack of Satiety
Interventions: OTHER: placebo|DIETARY_SUPPLEMENT: digestion-resistant maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Trial to Evaluate the Safety and Efficacy of a Fully Degradable Ventricular Septal Defect (VSD) Closure
Status: UNKNOWN
Conditions: Ventricular Septal Defect
Interventions: DEVICE: Fully Absorbable VSD Occlusion System|DEVICE: VSD Occluder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis
Status: UNKNOWN
Conditions: Knee Osteoarthritis
Interventions: DRUG: Hyruan-One|DRUG: Hylan G-F 20|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: KSD-101 Therapy for EBV-associated Haematologic Neoplasms: an Exploratory Clinical Trial
Status: ENROLLING_BY_INVITATION
Conditions: EBV-associated Haematologic Neoplasms
Interventions: BIOLOGICAL: Autologous monocyte - derived DCs pulsed with EBV antigen
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Anti-Xa Activity of ENOXA ® Versus LOVENOX ® in Acute Coronary Syndrome
Status: COMPLETED
Conditions: Acute Coronary Syndrome|Factor X
Interventions: DRUG: ENOXA®|DRUG: LOVENOX®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Interaction Between Drug and Placebo Effect:Randomized Placebo Controlled Trials May Not be Accurate in Determining Drug Effect Size
Status: COMPLETED
Conditions: Placebo Effect|Placebo Drug Interaction
Interventions: DRUG: Hydroxizine|OTHER: Placebo|DRUG: hydroxyzine/placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal Rebleeding
Status: COMPLETED
Conditions: Decompensated Cirrhosis|Portal Hypertension|Bleeding Varices
Interventions: DEVICE: 8-mm covered stent group|DEVICE: 10-mm covered stent group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trials on Laparoscopic No. 14v LNS Dissection
Status: UNKNOWN
Conditions: Stomach Neoplasms
Interventions: PROCEDURE: D2 lymphadenectomy including No. 14v|PROCEDURE: lymphadenectomy excluding No. 14v
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
Status: RECRUITING
Conditions: Opioid Use Disorder
Interventions: DRUG: Buprenorphine/naloxone|DRUG: Hydromorphone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Patient Positioning in Lumbar Fusion Surgery and Its Impact on Spinal Sagittal Balance and Surgeon Satisfaction
Status: TERMINATED
Conditions: Intervertebral Disk Degeneration
Interventions: OTHER: Hyperlordotic Positioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: PentoxIfylline and Tocopherol for the Treatment of Post-radiotherapy Fibrosis in Head and Neck Cancer Patients
Status: UNKNOWN
Conditions: Head and Neck Fibrosis
Interventions: COMBINATION_PRODUCT: Arm B: A combination of pentoxifylline and tocopherol acetate in addition to best standard care [a structured programme of rehabilitation exercises] for 6 months|PROCEDURE: • Arm A: Best standard of care only [a structured programme of rehabilitation exercises] for 6 months
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multivessel Disease Diagnosed at the Time of PPCI for STEMI: Complete Revascularization Versus Conservative Strategy.
Status: COMPLETED
Conditions: Coronary Artery Stenosis
Interventions: PROCEDURE: Percutaneous coronary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: First in Human Trial to Assess the Safety of HemoSystem REBOOT in Patients With Sepsis-induced Immunosuppression
Status: NOT_YET_RECRUITING
Conditions: Septic Shock
Interventions: DEVICE: Hemosystem REBOOT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Addiction Risk: Mindset Induction Effect on Brief Intervention
Status: TERMINATED
Conditions: Alcohol Drinking in College
Interventions: BEHAVIORAL: Induction of Implemental Mindset|BEHAVIORAL: Induction of Deliberative Mindset
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation (POPular ACE TAVI)
Status: RECRUITING
Conditions: Aortic Valve Stenosis
Interventions: DRUG: Protamine sulfate|DRUG: Protamine sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Iron Bisglycinate in Treatment of Iron Deficiency Anemia in Pregnant Women
Status: COMPLETED
Conditions: Iron Deficiency Anemia of Pregnancy
Interventions: DRUG: Iron bisglycinate Oral Tablet|DRUG: Ferrous Fumarate Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases
Status: RECRUITING
Conditions: Lupus Erythematosus, Systemic
Interventions: BIOLOGICAL: single dose of CNCT19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
Status: RECRUITING
Conditions: Refractory Chronic Cough
Interventions: DRUG: BLU-5937|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Preventive Effect of Photobiomodulation in the Postoperative Period of Extractions of Retained Lower Third Molars
Status: RECRUITING
Conditions: Molar, Third|Photobiomodulation
Interventions: DEVICE: Photobiomodulation|DRUG: Placebo Corticosteroid|DEVICE: Simulation Photobiomodulation|DRUG: Corticosteroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ischemic Preconditioning for Prevention of Contrast Nephropathy in The Emergency Department
Status: UNKNOWN
Conditions: Contrast-induced Nephropathy
Interventions: PROCEDURE: Ischemic preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin detemir|DIETARY_SUPPLEMENT: Dietary regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Black Soy Peptide Supplementation on Blood Pressure
Status: COMPLETED
Conditions: Hypertension
Interventions: DIETARY_SUPPLEMENT: black soy peptide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Neuregulin-1 in Patient With Different Forms of Cardiovascular Diseases: a Pilot Study
Status: COMPLETED
Conditions: Heart Failure With Preserved Ejection Fraction|Microvascular Angina|Pulmonary Hypertension|Heart Failure With Reduced Ejection Fraction
Interventions: DIAGNOSTIC_TEST: Neuregulin-1β level in plasma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS)
Status: COMPLETED
Conditions: Chronic Fatigue Syndrome (CFS)|Myalgic Encephalomyelitis (ME)
Interventions: DRUG: Cyclophosphamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children
Status: COMPLETED
Conditions: Malignant Glioma|Anaplastic Astrocytoma|Anaplastic Oligoastrocytoma|Anaplastic Oligodendroglioma|Glioblastoma|Gliosarcoma|Atypical Teratoid/Rhabdoid Tumor of Brain|Medulloblastoma|Ependymoma|Pleomorphic Xanthoastrocytoma of Brain|Embryonal Tumor of Brain
Interventions: BIOLOGICAL: Polio/Rhinovirus Recombinant (PVSRIPO)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma
Status: RECRUITING
Conditions: Mantle Cell Lymphoma
Interventions: DRUG: Acalabrutinib|DRUG: Bortezomib|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Doxorubicin Hydrochloride|DRUG: Prednisone|BIOLOGICAL: Rituximab|BIOLOGICAL: Rituximab and Hyaluronidase Human
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tools for Therapeutic Evaluation in Charcot-Marie-Tooth Disease Type 1A: Outcome Measures and Biomarkers
Status: RECRUITING
Conditions: Charcot-Marie-Tooth Disease Type 1A
Interventions: OTHER: Clinical evaluation|OTHER: electrophysiological record|OTHER: Muscle MRI|OTHER: blood samples analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Real-Time Ultrasound Guided Approach For Spinal Anesthesia
Status: COMPLETED
Conditions: Patients Aged 55 or Older|BMI More Than 40 kg/m2|Scoliosis
Interventions: OTHER: ultrasound-guided spinal anesthesia|OTHER: standard spinal anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Compassionate Case Study to Assess the Hypotensive Efficacy of Rho-Kinase Inhibitor AR-12286 Ophthalmic Solution 0.5% and 0.7% in Glaucoma Patients With Uncontrolled Intraocular Pressure to Avoid Surgical Intervention
Status: UNKNOWN
Conditions: Glaucoma
Interventions: DRUG: Rho-Kinase Inhibitor (AR-12286)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Anti-mesothelin CAR-T Cells With Advanced Refractory Solid Tumors
Status: UNKNOWN
Conditions: Refractory Malignant Solid Neoplasm
Interventions: BIOLOGICAL: anti-MESO CAR T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Lurasidone Compared With Placebo for the Treatment of Bipolar I Depression
Status: TERMINATED
Conditions: Bipolar I Depression
Interventions: DRUG: Lurasidone HCl|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries
Status: COMPLETED
Conditions: Pelvic Ring Fractures
Interventions: DRUG: Miacalcin Calcitonin Salmon Nasal Spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth-Enhanced Asthma Care for Home After the Emergency Room
Status: RECRUITING
Conditions: Asthma in Children
Interventions: BEHAVIORAL: Telehealth-Enhanced Asthma Care for Home After the Emergency Room (TEACH-ER)|BEHAVIORAL: Enhanced Care (EC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gastrointestinal Decompression in Stroke
Status: NOT_YET_RECRUITING
Conditions: Stroke|Stomach Acidity|Pulmonary Infection|Gastrointestinal Decompression
Interventions: PROCEDURE: Gastrointestinal decompression|PROCEDURE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: InertiaLocoGraphy as a Biomarker of Immunoglobulin Therapy Efficacy in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Status: WITHDRAWN
Conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Interventions: OTHER: Group with walking disorder|OTHER: Group without walking disorder
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Compassionate Access Protocol to Assess the Safety of XolairTM (Omalizumab) in Patients (≥ 6 Years Old) With Severe Allergic Asthma Who Remain Symptomatic Despite Optimal Therapy
Status: COMPLETED
Conditions: Asthma
Interventions: BIOLOGICAL: omalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Identification of Immunomodulators Associated With Atrial Fibrillation Reporting: Analysis of the WHO Pharmacovigilance Database
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Immunomodulators with FDA approval on the 1st January 2023.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pharmacokinetics and Pharmacodynamics of TAK-875 in Subjects With Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: TAK-875
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Transcervical Balloon Compared to Osmotic Dilators Prior to Surgical Abortion
Status: COMPLETED
Conditions: Abortion, Second Trimester
Interventions: DEVICE: Single Foley Balloon|DEVICE: Dilapan-S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Oral Care Protocol on Prevention of Oral Mucositis in Pediatric Cancer Patients
Status: COMPLETED
Conditions: Mucositis|Pediatric Cancer|Oral Cavity
Interventions: COMBINATION_PRODUCT: Oral care protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT)
Status: ACTIVE_NOT_RECRUITING
Conditions: Depression|Dementia|Mild Cognitive Impairment|Treatment Resistant Depression|Major Depressive Disorder|Treatment-Refractory Depression|Late Life Depression|Geriatric Depression
Interventions: DRUG: Aripiprazole Augmentation|DRUG: Bupropion Augmentation|DRUG: Switch to bupropion|DRUG: Lithium Augmentation|DRUG: Switch to nortriptyline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Myocardial Contrast Echocardiography (MCE) to Check for Living and Working Heart Muscle
Status: COMPLETED
Conditions: Coronary Disease|Heart Diseases
Interventions: PROCEDURE: Myocardial contrast echocardiography|PROCEDURE: Dobutamine echocardiography
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Dose-Escalation Study of T Cell Vaccine in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis, Relapsing-Remitting|Multiple Sclerosis, Secondary Progressive
Interventions: BIOLOGICAL: Tovaxin Autologous T Cell Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multimodal Intervention for Painful Diabetic Neuropathy: NeuOst Feasibility Trial
Status: RECRUITING
Conditions: Painful Diabetic Neuropathy
Interventions: OTHER: NeuOst|OTHER: Control Intervention|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Monotherapy and Consequent Therapy With Atezolizumab Plus Bevacizumab for NSCLC
Status: UNKNOWN
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Atezolizumab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pulmonary Aspergillosis in Tuberculosis Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Tuberculoses|Aspergillosis|Old Tuberculosis|Active Tuberculosis|Chronic Pulmonary Aspergillosis
Interventions: DIAGNOSTIC_TEST: Aspergillus IgG detection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories
Status: COMPLETED
Conditions: Intrusive Memories|PTSD
Interventions: DRUG: Oxytocin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Smartphone-Delivered Attentional Bias Modification Training in Helping Patients Quit Smoking
Status: COMPLETED
Conditions: Current Every Day Smoker
Interventions: BEHAVIORAL: Computer-Assisted Smoking Cessation Intervention|OTHER: Laboratory Biomarker Analysis|DRUG: Nicotine Patch|OTHER: Questionnaire Administration|OTHER: Sham Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Results of Extended Versus Single Dose Antibiotic Prophylaxis In Orthopedic Revision Arthroplasty in Nijmegen.
Status: ACTIVE_NOT_RECRUITING
Conditions: Infection Prosthesis Hip and Knee|Infection, Prosthesis Related|Joint Infection|Infection, Surgical Site|Surgical Site Infection|Infection Pro
Interventions: DRUG: Cefazolin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Trough and Peak Effect of Once Daily Telmisartan 80 mg/Hydrochlorothiazide 12.5 mg (Micardis Plus) by Ambulatory Blood Pressure Monitoring (ABPM) in Patients With Mild to Moderate Essential Hypertension
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Telmisartan|DRUG: Telmisartan/HCTZ
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Intake of Glycin Max (L.) Merr. Peel Extract on Body Fat and Body Weight
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Glycin max(L.) Merr. peel extract|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Detection of Biomarkers in Abnormal Cervical Cells in Women With Abnormal Pap Test Results
Status: COMPLETED
Conditions: Cervical Cancer
Interventions: OTHER: Papanicolaou test|OTHER: cytology specimen collection procedure|OTHER: fluorescent antibody technique|PROCEDURE: colposcopic biopsy|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mechanism Exploration of Anti-HER-2 Small-molecule Tyrosine Kinase Inhibitor-related Diarrhea and Establishment of Prevention and Treatment Model(Measure)
Status: RECRUITING
Conditions: Breast Cancer
Interventions: DRUG: Take probiotics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of Exparel TAP Block in Breast Free Flap Reconstruction
Status: COMPLETED
Conditions: Postoperative Pain|Breast Reconstruction
Interventions: DRUG: Liposomal bupivacaine TAP block|DRUG: Bupivacain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer
Status: TERMINATED
Conditions: Advanced Adult Primary Liver Cancer|Carcinoma of the Appendix|Fallopian Tube Cancer|Gastrointestinal Stromal Tumor|Localized Extrahepatic Bile Duct Cancer|Localized Gallbladder Cancer|Localized Gastrointestinal Carcinoid Tumor|Localized Resectable Adult Primary Liver Cancer|Localized Unresectable Adult Primary Liver Cancer|Metastatic Gastrointestinal Carcinoid Tumor|Ovarian Sarcoma|Ovarian Stromal Cancer|Primary Peritoneal Cavity Cancer|Recurrent Adult Primary Liver Cancer|Recurrent Adult Soft Tissue Sarcoma|Recurrent Colon Cancer|Recurrent Extrahepatic Bile Duct Cancer|Recurrent Gallbladder Cancer|Recurrent Gastric Cancer|Recurrent Gastrointestinal Carcinoid Tumor|Recurrent Non-small Cell Lung Cancer|Recurrent Ovarian Epithelial Cancer|Recurrent Ovarian Germ Cell Tumor|Recurrent Pancreatic Cancer|Recurrent Rectal Cancer|Recurrent Small Intestine Cancer|Recurrent Uterine Sarcoma|Regional Gastrointestinal Carcinoid Tumor|Small Intestine Adenocarcinoma|Small Intestine Leiomyosarcoma|Small Intestine Lymphoma|Stage 0 Non-small Cell Lung Cancer|Stage I Adult Soft Tissue Sarcoma|Stage I Colon Cancer|Stage I Gastric Cancer|Stage I Non-small Cell Lung Cancer|Stage I Ovarian Epithelial Cancer|Stage I Ovarian Germ Cell Tumor|Stage I Pancreatic Cancer|Stage I Rectal Cancer|Stage I Uterine Sarcoma|Stage II Adult Soft Tissue Sarcoma|Stage II Colon Cancer|Stage II Gastric Cancer|Stage II Non-small Cell Lung Cancer|Stage II Ovarian Epithelial Cancer|Stage II Ovarian Germ Cell Tumor|Stage II Pancreatic Cancer|Stage II Rectal Cancer|Stage II Uterine Sarcoma|Stage III Adult Soft Tissue Sarcoma|Stage III Colon Cancer|Stage III Gastric Cancer|Stage III Ovarian Epithelial Cancer|Stage III Ovarian Germ Cell Tumor|Stage III Pancreatic Cancer|Stage III Rectal Cancer|Stage III Uterine Sarcoma|Stage IIIA Non-small Cell Lung Cancer|Stage IIIB Non-small Cell Lung Cancer|Stage IV Adult Soft Tissue Sarcoma|Stage IV Colon Cancer|Stage IV Gastric Cancer|Stage IV Non-small Cell Lung Cancer|Stage IV Ovarian Epithelial Cancer|Stage IV Ovarian Germ Cell Tumor|Stage IV Pancreatic Cancer|Stage IV Rectal Cancer|Stage IV Uterine Sarcoma|Unresectable Extrahepatic Bile Duct Cancer|Unresectable Gallbladder Cancer
Interventions: DRUG: EF5|DRUG: motexafin lutetium|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Single Shot Versus OnQ Pump in Extremity Fractures
Status: COMPLETED
Conditions: Pain|Fracture
Interventions: DRUG: Ankle SSB|DRUG: Ankle OnQ|DRUG: DR SSB|DRUG: DR OnQ
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App
Status: COMPLETED
Conditions: Arthroplasties, Replacement|Weight Loss|Nutrition
Interventions: BEHAVIORAL: Remote dietitian supervised weight loss intervention and mobile app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Local Anesthetic Injection Into Both Angles of the Rectus Sheath Incision
Status: COMPLETED
Conditions: Postoperative Cesarean Delivery Pain
Interventions: DRUG: 10ml of bupivacaine 0.5%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surveillance of Patients With Precancerous Lesions of the Stomach
Status: RECRUITING
Conditions: Gastric Cancer|Gastric Intestinal Metaplasia|Gastric Atrophy|Gastric Dysplasia
Interventions: PROCEDURE: Upper endoscopy with biopsies|PROCEDURE: Plasma/serum sampling|PROCEDURE: Biopsies for gastric microbiota|PROCEDURE: Faecal sample acquisition
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Anti-oxidants on Clinical Outcomes and Radiological Features of Chronic Spinal Cord Injury: A Pilot Study
Status: COMPLETED
Conditions: Spinal Cord Injury
Interventions: DIETARY_SUPPLEMENT: Selenium|DIETARY_SUPPLEMENT: Vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combined THC and CBD for OUD and Chronic Pain
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Opioid Use Disorder
Interventions: DRUG: CBD 300mg|DRUG: CBD 600mg|DRUG: Placebo 0mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Response Profiles to High-concentration Capsaicin Desensitization in Patients With Peripheral Neuropathic Pain With or Without Allodynia: a Regional Multicenter Prospective Cohort
Status: RECRUITING
Conditions: Peripheral Neuropathic Pain
Interventions: OTHER: Questionnaires
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: RENABLATE-II Feasibility Study of Catheter Based Renal Denervation to Treat Resistant Hypertension - 157
Status: COMPLETED
Conditions: Hypertension, Renal
Interventions: DEVICE: Celsius® ThermoCool® Renal Denervation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Rehydration Efficiency During Ad-libitum Fluid Intake
Status: RECRUITING
Conditions: Dehydration
Interventions: OTHER: Plain Water|OTHER: Liquid IV Hydration Multiplier|OTHER: Liquid IV Sugar Free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Intensive Chemotherapy and Rituximab in the Treatment of Burkitt Lymphoma
Status: TERMINATED
Conditions: Burkitt Lymphoma|Non-Hodgkins Lymphoma|Atypical Burkitt Lymphoma
Interventions: DRUG: Rituximab|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Vincristine|DRUG: Methotrexate|DRUG: Leucovorin|DRUG: Ifosfamide|DRUG: Etoposide|DRUG: Cytarabine|DRUG: Mesna
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Applicability of 3T Shoulder MRI in Detection of Labral Pathology
Status: NOT_YET_RECRUITING
Conditions: Labral Tear, Glenoid
Interventions: RADIATION: 1.5 Tesla magnet MR arthrography|RADIATION: 3 Tesla magnet non-contrast MRI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML) and Hydrochlorothiazid (HCTZ) in Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: olmesartan medoxomil + amlodipine + hydroclororthiazide + placebo|DRUG: Olmesartan medoxomil + amlodipine + hydrochlorothiazide + placebo|DRUG: olmesartan medoxomil + amlodipine + hydroclororthiazide|DRUG: olmesartan medoxomil + amlodipine + hydroclororthiazide|DRUG: olmesartan medoxomil + amlodipine + hydroclororthiazide|DRUG: olmesartan medoxomil + amlodipine|DRUG: olmesartan medoxomil + amlodipine|DRUG: olmesartan medoxomil + amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Additional Effect of Hallux Valgus Correction on Runners With First Ray Instability and Patellofemoral Pain Syndrome
Status: COMPLETED
Conditions: Patellofemoral Pain Syndrome|Hallux Valgus
Interventions: OTHER: combined training|OTHER: Proximal training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent
Status: RECRUITING
Conditions: Coronary Artery Disease
Interventions: OTHER: Angiography-derived physiology guidance/Local routine diagnostic procedure (LRDP) and usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Palifosfamide-tris in Combination With Doxorubicin in Patients With Front-line Metastatic Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Soft Tissue Sarcoma
Interventions: DRUG: doxorubicin in combination with palifosfamide-tris|DRUG: doxorubicin in combination with placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Anterior Cruciate Ligament Reconstruction (Quadriceps Versus Hamstring Tendon)
Status: COMPLETED
Conditions: Acute Injury of Anterior Cruciate Ligament
Interventions: PROCEDURE: QUADRICEPS TENDON|PROCEDURE: HAMSTRING TENDON
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, and Pharmacokinetics of IRL201104 in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: IRL201104|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders
Status: UNKNOWN
Conditions: Vulvovaginal Signs and Symptoms|Genitourinary Syndrome of Menopause|Sexual; Disorder, Arousal, Female
Interventions: DRUG: Ospemifene 60 mg|BEHAVIORAL: fMRI experiments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy and Safety of PRO-155 on Inflammation of the Conjunctival Surface in Subjects With Grade I-III Pterygium vs Placebo.
Status: COMPLETED
Conditions: Pterygium|Ocular Pain|Ocular Inflammation|Post-surgical Inflammation
Interventions: DRUG: PRO-155|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Reduce Drinking in Women With HIV
Status: COMPLETED
Conditions: HIV Infection
Interventions: DRUG: Naltrexone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Taxotere Combinations as First Line Therapy for Locally Advanced Unresectable or Metastatic Non-small Cell Lung Cancer.
Status: COMPLETED
Conditions: Non-small Cell Lung Cancer
Interventions: DRUG: Docetaxel and Gemcitabine|DRUG: Docetaxel and Gemcitabine|DRUG: Gemcitabine cisplatin followed by docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Long-term Efficacy and Safety of HMS5552 in T2DM Subjects
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: HMS5552|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Paliperidone ER Observational Study of Economic, Functional, and Clinical Outcomes in Patients With Schizophrenia
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER|DRUG: Atypical antipsychotics (AAP)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Implementation of Prevention and Intervention of Maternal Perinatal Depression to Strengthen Maternal and Child Health
Status: RECRUITING
Conditions: Perinatal Depression
Interventions: BEHAVIORAL: 'Enjoy your Bump' (iloodottaa.fi) online self-help intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Comparison of the Ambu®AuraGain™ and the Laryngeal Mask Airway Supreme™ in Normal Airway Patients
Status: UNKNOWN
Conditions: Supraglottic Airway
Interventions: DEVICE: Ambu AuraGain|DEVICE: LMA Supreme
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fast Track Laparoscopic Surgery: A Better Option for Treating Colorectal Cancer Than Conventional Laparoscopic Surgery
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: PROCEDURE: fast-track surgery|OTHER: conventional postoperative surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Risperdal Consta and Health Care Utilization in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Risperdal Consta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Obstructive Sleep Apnea Treatment With CPAP With and Without the Use of Expiratory Pressure Relief Technology
Status: ACTIVE_NOT_RECRUITING
Conditions: Obstructive Sleep Apnea
Interventions: DEVICE: EPR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: RY_SW01 Cell Injection Therapy in Systemic Sclerosis
Status: RECRUITING
Conditions: Systemic Sclerosis
Interventions: DRUG: RY_SW01 cell injection|DRUG: Basic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: CHRONIC OBSTRUCTIVE PULMONARY DISEASE|ASTHMA|HEALTHY SUBJECTS
Interventions: DRUG: SALBUTAMOL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Lixisenatide on Postprandial Plasma Glucose Compared to Sitagliptin in Combination With Insulin Glargine
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: LIXISENATIDE AVE0010|DRUG: Sitagliptin|DRUG: Insulin glargine HOE901
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nano-Crystalline Ceramic Coating of Orthodontic Archwires
Status: WITHDRAWN
Conditions: Malocclusion
Interventions: DEVICE: Ceramic coated orthodontic archwire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multi-disciplinary Treatment for Patients Experiencing First Episode of Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Schizophreniform Disorder|Delusional Disorder|Psychosis
Interventions: BEHAVIORAL: Multi-element, team-oriented treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Status: NOT_YET_RECRUITING
Conditions: Hypertension
Interventions: DEVICE: TIVUS™ Renal Denervation System|OTHER: Sham
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Effects of Using Black Seed and Cumin Seed on BCP of Obese Grade I
Status: RECRUITING
Conditions: Obese
Interventions: DIETARY_SUPPLEMENT: Black Seed ( Nigella Sativa)|DIETARY_SUPPLEMENT: Cumin Seed (Cuminum Cyminum)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: : Pulpal Blood Flow With the Use of Intra-nasal Anesthetic
Status: UNKNOWN
Conditions: Local Anesthetic Drug Adverse Reaction|Local Infiltration|Pulp Disease, Dental
Interventions: DRUG: tetracaine HCl and oxymetazoline HCL|DRUG: 2% Lidocaine with 1:100,000 epinephrine|DRUG: 3% Mepivacaine with 1:100,000 epinephrine|DRUG: saline intranasal|DRUG: saline infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer
Status: RECRUITING
Conditions: HER2-positive Metastatic Breast Cancer|Stage IV Breast Cancer
Interventions: OTHER: Discontinuation of Anti-HER-2 Maintenance Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis
Status: NOT_YET_RECRUITING
Conditions: Knee Osteoarthritis
Interventions: DRUG: Topical Diclofenac gel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Propofol to Precedex With Propofol for Emergence and Recovery in Patients Having Craniotomy Surgery
Status: COMPLETED
Conditions: Cranitomy Surgery
Interventions: DRUG: Precedex|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DRUG: Tiotropium|DRUG: Salmeterol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Vital HEAT (vH2) Temperature Management System to Upper-body Forced-air Warming
Status: COMPLETED
Conditions: Surgery
Interventions: DEVICE: a forced-air warming cover|DEVICE: vital HEAT (vH2) Temperature Management System
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Exploring the Mechanisms of Indoxyl Sulfate Production by Oral Tryptophan Challenge Test
Status: COMPLETED
Conditions: Healthy|Chronic Kidney Diseases
Interventions: DIETARY_SUPPLEMENT: Doctor's Best L-Tryptophan
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of LY2127399 in Participants With Systemic Lupus Erythematosus
Status: COMPLETED
Conditions: Systemic Lupus Erythematosus|Connective Tissue Disease|Autoimmune Disease
Interventions: DRUG: LY2127399|DRUG: Placebo every 2 weeks|DRUG: Placebo every 4 weeks|DRUG: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Wavefront-guided LASIK for Monovision Treatment of Myopic Subjects With Presbyopia
Status: RECRUITING
Conditions: Refractive Error
Interventions: DEVICE: iDesign Refractive Studio with STAR S4 IR® Excimer laser System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Ofatumumab and Bortezomib in Subjects With Relapsed CD20+Diffuse Large B Cell, Follicular, or Mantle Cell Lymphoma
Status: TERMINATED
Conditions: Recurrent Adult Diffuse Large Cell Lymphoma|Recurrent Grade 1 Follicular Lymphoma|Recurrent Grade 2 Follicular Lymphoma|Recurrent Grade 3 Follicular Lymphoma|Recurrent Mantle Cell Lymphoma
Interventions: BIOLOGICAL: Ofatumumab|DRUG: Bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy With or Without G-CSF in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
Status: COMPLETED
Conditions: Endometrial Cancer
Interventions: BIOLOGICAL: filgrastim|DRUG: cisplatin|DRUG: doxorubicin hydrochloride|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Novel Nutrition Solutions for Sarcopenia
Status: COMPLETED
Conditions: Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: Leucine-enriched protein|DIETARY_SUPPLEMENT: LC n-3 PUFA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of Ketamine on Mentalizing and Metacognition in Healthy Volunteers
Status: COMPLETED
Conditions: Ketamine-Induced Psychotic Disorder|Social Cognition|Theory of Mind
Interventions: DRUG: Ketamine|DRUG: Nacl 0.9%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
Status: RECRUITING
Conditions: Spinal Cord Injuries|Cerebral Palsy|Spinal Dysraphism|Brain Injuries|Spina Bifida|Traumatic Brain Injury
Interventions: DEVICE: MHealth
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of Combination Ruxolitinib and Decitabine Treatment for Accelerated Phase MPN or Post-MPN AML
Status: COMPLETED
Conditions: Myeloproliferative Neoplasms
Interventions: DRUG: Ruxolitinib|DRUG: Decitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Investigation of Performance and Safety of the Wound Dressing FibDex in Patients With Superficial Dermal Burns
Status: RECRUITING
Conditions: Burns
Interventions: DEVICE: FibDex|DEVICE: Epicite hydro|DEVICE: Epiprotect
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The CHAMP-study: The CHemopreventive Effect of Lithium in Familial AdenoMatous Polyposis
Status: ACTIVE_NOT_RECRUITING
Conditions: Familial Adenomatous Polyposis
Interventions: DRUG: Lithium Carbonate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Orlistat/Phentermine Versus Placebo/Phentermine
Status: COMPLETED
Conditions: Obesity|Overweight
Interventions: DRUG: Orlistat 120Mg Cap|DRUG: Phentermine Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Evaluation Complementary Spirit Therapy
Status: RECRUITING
Conditions: Anxiety|Depression|Pain|Well-being|Stress
Interventions: OTHER: Complementary Spiritist Therapy|OTHER: Prayer|OTHER: Spiritist "passe"|OTHER: laying on of hands with intent to heal|OTHER: Fluid therapy.|OTHER: No-fluid therapy.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Study of the PD-L1 Inhibitor Atezolizumab With or Without Low-dose, Local Radiation in Patients With Relapsed or Refractory Advanced Stage Follicular Lymphoma
Status: TERMINATED
Conditions: Lymphoma
Interventions: DRUG: atezolizumab|RADIATION: Low- Dose, Local Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endovascular Recanalization and Standard Medical Management for Symptomatic Nonacute Intracranial Artery Occlusion Trial
Status: UNKNOWN
Conditions: Intracranial Artery Occlusion With Infarction
Interventions: BIOLOGICAL: endovascular recanalization
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing Two Types of Swabs in Collecting Cell Samples for Anal Pap Tests and Human Papillomavirus Tests in Men Who Have Sex With Men
Status: COMPLETED
Conditions: Anal Cancer|Nonneoplastic Condition|Precancerous Condition
Interventions: OTHER: Papanicolaou test
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING