pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Myocardial Regional Function by Dobutamine Stress Echocardiography in the Metabolic Syndrome and Type 2 Diabetes
Status: COMPLETED
Conditions: Diabetes-related Complications
Interventions: DRUG: dobutamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effectiveness of Iguratimod Versus Placebo to Treat Early Rheumatoid Arthritis on MRI
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Iguratimod|DRUG: Iguratimod placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Dose Omega 3 in People at Risk for Dementia
Status: UNKNOWN
Conditions: Dementia|Inflammation|Mild Cognitive Impairment|Cognitive Decline|SCD|Cognitive Dysfunction|Pathologic Processes|Brain Diseases|Central Nervous System Diseases|Nervous System Diseases|Neurocognitive Disorders|Mental Disorder|Cognition Disorders
Interventions: DIETARY_SUPPLEMENT: Omega-3 capsules|DIETARY_SUPPLEMENT: Olive oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea
Status: COMPLETED
Conditions: COPD|Lung Diseases|Dyspnea|Hypoxemia|Tachycardia
Interventions: DRUG: Indacaterol maleate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of Clonidine in Pain and Anxiety Associated With Acute Burn Injury in Children
Status: TERMINATED
Conditions: Pain|Anxiety
Interventions: DRUG: clonidine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases
Status: RECRUITING
Conditions: Metastatic Malignant Neoplasm in the Brain|Metastatic Malignant Solid Neoplasm
Interventions: OTHER: Best Practice|BEHAVIORAL: Neuropsychological Assessment|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hybrid Exercise Training for Health, Performance and Well-Being (DoIT II)
Status: COMPLETED
Conditions: High-Intensity Interval Training|Body Composition|Performance|Habitual Physical Activity
Interventions: BEHAVIORAL: DoIT-1|BEHAVIORAL: DoIT-2|BEHAVIORAL: DoIT-3|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: High Protein Diet in Patients With Long-chain Fatty Acid Oxidation Disorders
Status: COMPLETED
Conditions: Very Long-chain Acyl-CoA Dehydrogenase Deficiency|Trifunctional Protein Deficiency|Carnitine Palmitoyltransferase 2 Deficiency|Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency
Interventions: BEHAVIORAL: Diet counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety of Verorab™ in Indian Population
Status: COMPLETED
Conditions: Rabies
Interventions: BIOLOGICAL: Purified Verocell Rabies Vaccine|BIOLOGICAL: Purified Verocell Rabies Vaccine|BIOLOGICAL: Purified Verocell Rabies Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC)
Status: TERMINATED
Conditions: Ulcerative Colitis|FMT|Fecal Microbiota Transplant
Interventions: DRUG: Metronidazole|DRUG: Placebo|DRUG: Vancomycin|BIOLOGICAL: Fecal Microbiota Transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Staying Healthy After Childbirth: My Hypertension Education and Reaching Target Program for Postpartum
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension
Interventions: OTHER: Health Coaching|OTHER: Home Blood Pressure Monitoring
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hysteroscopic Injections of Autologous Endometrial Cells and Platelet-rich Plasma in Patients With Thin Endometrium
Status: COMPLETED
Conditions: Thin Endometrium
Interventions: PROCEDURE: Conservative therapy|BIOLOGICAL: PRP injection|BIOLOGICAL: Injection of PRP after conservative therapy|BIOLOGICAL: Injection of PRP with endometrial cells
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Effect of Superficial Cervical Plexus Block on Post Operative Nausea and Vomiting in Tympanomastoid Operations
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: PROCEDURE: ultrasound guided superficial cervical plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Performance Study to Test the GlucoMen®Day System Using Intravascular and Subcutaneous Microdialysis in Subjects With Type 1 Diabetes
Status: COMPLETED
Conditions: Type 1 Diabetes
Interventions: DEVICE: Vascular microdialysis using the GMD-system|DEVICE: Vascular and subcutaneous microdialysis using the GMD-system
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effect of Real-time Computer-aided System (ENDO-AID) on Adenoma Detection in Endoscopist-in-training
Status: COMPLETED
Conditions: Screening Colonoscopy
Interventions: DEVICE: ENDO-AID CADe
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK962040 Administered to Healthy Adult Subjects.
Status: COMPLETED
Conditions: Gastroparesis
Interventions: DRUG: GSK962040|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study to Compare Two Formulations of Deanxit®
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: test treatment: flupentixol/melitracen|DRUG: reference treatment: flupentixol/melitracen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Aminophylline and Cognitive Function After Sevoflurane Anaesthesia
Status: COMPLETED
Conditions: Anaesthesia
Interventions: DRUG: Placebo [group P]|DRUG: 0.2 mL/kg of aminophylline 10 mg/mL [group A2]|DRUG: 0.2 mL/kg of aminophylline 15 mg/mL [group A3]|DRUG: 0.2 mL/kg of aminophylline 20 mg/mL [group A4]|DRUG: 0.2 mL/kg of aminophylline 25 mg/mL [group A5]|DRUG: Doxapram 1 mg/kg [group D]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Effectiveness of Giving Indinavir, Ritonavir, Stavudine, and Lamivudine to HIV-Infected Patients Who Have Never Received Anti-HIV Drugs
Status: UNKNOWN
Conditions: HIV Infections
Interventions: DRUG: Indinavir sulfate|DRUG: Ritonavir|DRUG: Lamivudine|DRUG: Stavudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Sleep Apnea-Hypopnea Syndrome and the Pathogenesis of Obesity
Status: UNKNOWN
Conditions: Sleep Apnea|Obesity
Interventions: DEVICE: CPAP (Continuous Positive Airway Pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Food Study of Ciprofloxacin Extended-Release Tablets 1000 mg and Cipro® XR Tablets 1000 mg
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ciprofloxacin Extended-Release Tablets 1000 mg|DRUG: Cipro® XR Tablets 1000 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gasdermin-D and Pannexin-1 in Pregnancy
Status: COMPLETED
Conditions: Pregnancy Complications|Maternal Obesity
Interventions: DIAGNOSTIC_TEST: Biomarker measurement of pannexin-1 and gasdermin-D
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Phenylephrine Versus Tranexamic Acid to Control Bleeding in Patients Undergoing Inferior Turbinoplasty by Coblation
Status: NOT_YET_RECRUITING
Conditions: Intraoperative Bleeding|Coblation Turbinoplasty
Interventions: DRUG: Topical Phenylephrine Solution|DRUG: intravenous tranexamic acid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anticoagulation Strategies for Acute Venous Thromboembolism in Patients With End-Stage Renal Disease Using USRDS Data
Status: COMPLETED
Conditions: Venous Thromboembolic Disease|Kidney Failure, Chronic
Interventions: DRUG: Warfarin|DRUG: Apixaban
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: China Stroke Primary Prevention Trial 2 for Participants With Hypertension and MTHFR 677 TT Genotype
Status: NOT_YET_RECRUITING
Conditions: Hypertension|MTHFR 677 TT Genotype
Interventions: DRUG: Amlodipine besylate|DRUG: Amlodipine besylate And Folic Acid|DRUG: 5-methyltetrahydrofolate (5-MTHF)|DRUG: Amlodipine placebo|DRUG: Amlodipine folic acid placebo|DRUG: 5-MTHF Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cannabidiol Treatment in Patients With Early Psychosis
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder
Interventions: DRUG: Cannabidiol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases
Status: COMPLETED
Conditions: Hormone Refractory Prostate Cancer|Bone Metastases
Interventions: DRUG: Radium-223 dichloride (Xofigo, BAY88-8223)|DRUG: Placebo|DRUG: Best standard of care (BSoC)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: MCARH109 Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of Multiple Myeloma
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: BIOLOGICAL: Infusion of MCARH109 T cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of T4 Versus T4/T3 on Psychological Distress After Total Thyroidectomy in Thyroid Cancer Patients
Status: COMPLETED
Conditions: Thyroid Cancer|Distress|Depression|Anxiety|Fatigue
Interventions: DRUG: Comthyroid|DRUG: Synthroid
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of ChimeriVax™ Tetravalent Dengue Vaccine in Healthy Peruvian Children Aged 2 to 11 Years
Status: COMPLETED
Conditions: Dengue Virus|Dengue Fever|Dengue Hemorrhagic Fever|Dengue Diseases
Interventions: BIOLOGICAL: CYD Dengue Vaccine Serotypes 1, 2, 3, and 4|BIOLOGICAL: Pneumococcal polysaccharide vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: TMC125-TiDP2-C238: An Exploratory Pharmacokinetics, Safety and Anti-HIV Activity Study of Etravirine (ETR) When Given With Boosted Atazanavir (ATV/Rtv) at Two Different Doses and 1 Nucleoside Reverse Transcriptase Inhibitor (NRTI) in Treatment Experienced HIV Patients
Status: COMPLETED
Conditions: HIV Infections|Acquired Immunodeficiency Syndrome
Interventions: DRUG: Atazanavir (ATV) 300 mg|DRUG: Atazanavir (ATV) 400 mg|DRUG: Ritonavir (rtv) 100 mg|DRUG: Nucleo(side)/(tide) reverse transcriptase inhibitors (NRTIs)|DRUG: Etravirine (ETR) 200 mg|DRUG: Tenofovir disoproxil fumarate (TDF) 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Iron Supplementation in Inflammatory Bowel Disease (IBD) Patients With Chronic Fatigue
Status: UNKNOWN
Conditions: Chronic Fatigue|Inflammatory Bowel Disease
Interventions: DRUG: Ferric carboxymaltose|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects Of Losartan On Myocardial Structure In Diabetic Hypertensive Patients With Left Ventricular
Status: UNKNOWN
Conditions: Essential Hypertension|Diabetes Mellitus
Interventions: DRUG: Losartan|DRUG: Amlodipine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 4D FLOW: Feasibility Study of a Sequence 4D of Flow Applied to the Cervico-encephalic Vascular Pathologies
Status: COMPLETED
Conditions: Cerebro-vascular Disease
Interventions: OTHER: Pilot MRI program|OTHER: MRI with 4D Flow sequence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Parasternal Nerve Block in Cardiac Patients
Status: COMPLETED
Conditions: Coronary Artery Disease|Pain, Postoperative
Interventions: DRUG: Exparel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of JS004 in Advanced Solid Tumors
Status: UNKNOWN
Conditions: Melanoma|Renal Carcinoma|Urothelial Carcinoma
Interventions: BIOLOGICAL: JS004, a recombinant humanized, IgG4κ monoclonal antibody (mAb) specific to B- and T-lymphocyte attenuator (BTLA); Toripalimab Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: CPP-ACPF and Laser's Effect on Dentin Hypersensitivity
Status: COMPLETED
Conditions: Dentin Sensitivity
Interventions: OTHER: Placebo|OTHER: CPPACPF|OTHER: Laser|OTHER: LaserCPPACPF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Status: UNKNOWN
Conditions: Whole Body Imaging|Magnetic Resonance Imaging|Neurofibromatosis 1|Diffusion Magnetic Resonance Imaging|Peripheral Nerve Sheath Tumors, Malignant
Interventions: OTHER: Additional imaging or surgery
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Osteosynthesis of Intraarticular Calcaneal Fractures: Arthroscopically Assisted Percutaneous Technique Versus Sinus Tarsi Approach
Status: RECRUITING
Conditions: Calcaneus Fracture
Interventions: PROCEDURE: Sinus tarsi approach (STA)|PROCEDURE: Percutaneous Arthroscopically Assisted Osteosynthesis (PACO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemoradiation Following Radical Resection of Pancreatic Ductal Adenocarcinoma, a Prospective Cohort Study
Status: UNKNOWN
Conditions: Resectable Pancreatic Cancer|Adjuvant Chemoradiotherapy|Surgery
Interventions: OTHER: Follow-up only|DRUG: Adjuvant chemotherapy|RADIATION: Adjuvant chemoradiotherapy|RADIATION: Adjuvant chemoradiotherapy + Adjuvant chemotherapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Zemplar Capsule in Reducing Serum iPTH Levels in Chronic Kidney Disease Subjects (Three Times Weekly)
Status: COMPLETED
Conditions: Renal Insufficiency, Chronic
Interventions: DRUG: paricalcitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods
Status: UNKNOWN
Conditions: Lower Urinary Tract Symptoms|Voiding Dysfunction|Benign Prostate Obstruction|Detrusor Underactivity
Interventions: PROCEDURE: Urodynamics|PROCEDURE: Usual care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Two Anesthetic Techniques in Magnetic Resonance Imaging (MRI)
Status: TERMINATED
Conditions: Magnetic Resonance Imaging|Anesthesia
Interventions: DRUG: dexmedetomidine|DRUG: propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Magnetic Resonance Adenosine Perfusion Imaging as Gatekeeper of Invasive Coronary Intervention
Status: COMPLETED
Conditions: Stable Coronary Artery Disease|Cardiac Magnetic Resonance Imaging|Coronary Angiography|Myocardial Revascularization|Outcomes and Prognosis|Quality of Life
Interventions: OTHER: diagnostic test - cardiac magnetic resonance imaging|OTHER: diagnostic test - coronary angiography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Oral Triple Combination Antiviral Drug Therapy for Treatment of Influenza A in Immunocompromised Subjects
Status: COMPLETED
Conditions: Influenza
Interventions: DRUG: Oseltamivir Phosphate|DRUG: ADS-8902
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Joint Application of Human Insulin and Rapid Insulin Analogue in Control of Postprandial Glycemia
Status: UNKNOWN
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Combined prandial insulin therapy (CPIT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomised, Open-Label, Cross Over Group, Single-Centre Controlled Study To Evaluate The Clinical Performance Of Medium Cut-Off Membrane Dialyser Compared With High Flux Dialyser Among Patients With Chronic Haemodialysis
Status: COMPLETED
Conditions: Hemodialysis-Associated Amyloidosis|Dialysis Amyloidosis|Quality of Life
Interventions: DEVICE: Theranova 400|DEVICE: Elisio-19H
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Optimization Post-TAVR to IMprove Activity Levels (OPTIMAL Study)
Status: RECRUITING
Conditions: Aortic Valve Disease|Aortic Valve Replacement
Interventions: BEHAVIORAL: Standard of Care plus Enhanced Patient Education|BEHAVIORAL: Motivational Interviewing Intervention|BEHAVIORAL: Home-Based Activity Program plus Motivational Interviewing Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment For Acute Coronary Syndromes Trial
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Prasugrel|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intravenous Ibuprofen for Laparoscopic Bariatric Surgery
Status: COMPLETED
Conditions: Obesity
Interventions: DRUG: Intravenous Ibuprofen|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Lanraplenib (LANRA) in Combination With Gilteritinib in Participants With FLT3-mutated Relapsed or Refractory Acute Myeloid Leukemia (AML)
Status: TERMINATED
Conditions: Acute Myeloid Leukemia|Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia
Interventions: DRUG: Lanraplenib|DRUG: Gilteritinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: TAXUS ARRIVE 2: A Multi-Center Safety Surveillance Program
Status: COMPLETED
Conditions: Cardiovascular Disease|de Novo Coronary Lesions
Interventions: DEVICE: TAXUS™ Express2™ Paclitaxel-Eluting Coronary Stent System
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial Comparing Dose-intensified SBRT With Conventional Radiation Therapy for Spinal Metastases
Status: ACTIVE_NOT_RECRUITING
Conditions: Spinal Metastasis
Interventions: RADIATION: dose-intensified image-guided SBRT using simultaneous integrated boost|RADIATION: External 3-dimensional conformal radiotherapy (3D-CRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Association Between Intakes of Protein, Calcium and Milk With Gene Expression and Linear Growth of School Aged Children
Status: COMPLETED
Conditions: Nutritional Stunting|Nutritional Anemia|Nutritional Deficiency|Nutrigenetic|Nutrigenomic|Linear Programming|Food Based Recommendation
Interventions: DIETARY_SUPPLEMENT: Milk supplementation|OTHER: Food Based Recommendation (FBR) nutrition education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Camrelizumab, Nab-paclitaxel and Carboplatin in Stage IB-IIIA NSCLC
Status: UNKNOWN
Conditions: Lung Cancer, Non-small Cell|Artificial Intelligence
Interventions: DRUG: Camrelizumab + Nab-paclitaxel + Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of SHR-1703 in Subjects With Eosinophilic Granulomatosis With Polyangiitis （EGPA）
Status: RECRUITING
Conditions: Eosinophilic Granulomatosis With Polyangiitis
Interventions: DRUG: SHR-1703|DRUG: SHR-1703 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ACT1VATE: Addressing Emotional Distress to Improve Outcomes Among Diverse Adults With Type 1 Diabetes
Status: RECRUITING
Conditions: Type 1 Diabetes
Interventions: BEHAVIORAL: ACT1VATE|BEHAVIORAL: DSME/S
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Adult Solid Tumor
Interventions: BIOLOGICAL: SQZ-PBMC-HPV|DRUG: Atezolizumab|DRUG: Ipilimumab|DRUG: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Analgesic Efficacy Between a Single Dose of ORG 28611, Morphine, and Placebo After Dental Impaction Surgery (Study P05800)
Status: TERMINATED
Conditions: Analgesia
Interventions: DRUG: Org 28611|DRUG: morphine sulfate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Interaction Between Metformin and Acute Exercise
Status: COMPLETED
Conditions: Impaired Glucose Tolerance|Diabetes Mellitus, Type 2
Interventions: DRUG: Metformin treatment|DRUG: Placebo treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Efficacy and Safety of PerioChip Plus (Flurbiprofen/Chlorhexidine) Formulation in the Therapy of Adult Periodontitis
Status: COMPLETED
Conditions: Periodontitis
Interventions: DRUG: PerioChip Plus (Flurbiprofen +Chlorhexidine ), Flurbiprofen Chip, PerioChip (Chlorhexidine ) and Placebo Chip
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic Study of Two Generic Co-formulations of Lopinavir/Ritonavir for HIV Infected Children (SURF)
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Lopinavir/ritonavir|DRUG: Lopinavir/ritonavir|DRUG: Lopinavir/ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Doxazosin for Psychostimulant Dependence
Status: COMPLETED
Conditions: Methamphetamine or Cocaine Dependence
Interventions: DRUG: Doxazosin extended release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Purified Vero Rabies Vaccine Compared With a Reference Rabies Vaccine as Simulated Rabies Post-Exposure Prophylaxis in Adults in Thaïland
Status: COMPLETED
Conditions: Rabies (Healthy Volunteers)
Interventions: BIOLOGICAL: Purified vero rabies vaccine - serum free|BIOLOGICAL: Purified inactivated rabies vaccine|BIOLOGICAL: Human rabies immunoglobulins
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Single Dose Gonadotropin-releasing Hormone (GnRH) Agonist Administration in the Luteal Phase of GnRH Antagonist Stimulated ICSI-ET Cycles
Status: TERMINATED
Conditions: Infertility
Interventions: DRUG: triptorelin acetate|DRUG: NaCl %0.9
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose:
Clinical trial: Comparison of Laparoscopic Versus Open Gastrectomy for Gastric Cancer: A Prospective Randomized Trial
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: PROCEDURE: laparoscopy-assisted distal gastrectomy|PROCEDURE: open distal gastrectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: paliperidone|DRUG: risperidone|DRUG: haloperidole|DRUG: perphenazine|DRUG: aripiprazole|DRUG: quetiapine|DRUG: paliperidone palmitate|DRUG: olanzapine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of an Investigational Multi-Purpose Solution (MPS)
Status: COMPLETED
Conditions: Study Focus is Healthy Contact Lens Wearers
Interventions: DEVICE: Investigational MPS|DEVICE: Opti-Free
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Pilot Study to Finetune Skin Processing Procedures in Recent Vaccinees, Prior to GeKoSkimm Study Initiation (GeKoSkimm-pilot)
Status: NOT_YET_RECRUITING
Conditions: Yellow Fever
Interventions: OTHER: Skin biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Rituximab in Adult Acquired Idiopathic Thrombotic Thrombocytopenic Purpura
Status: COMPLETED
Conditions: Thrombotic Thrombocytopenic Purpura
Interventions: DRUG: rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab
Status: RECRUITING
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome
Interventions: DRUG: Ocrelizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Acute Effect of a Mobilization With Movement Technique to Improve Internal Rotation of the Shoulder
Status: COMPLETED
Conditions: Disorder of Shoulder|Other Musculoskeletal Disorder|Contracture
Interventions: OTHER: Posterior capsule stretching|OTHER: Mobilization with movement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Evaluate UV-light-induced Allergic Skin Reactions After Application of Delgocitinib Cream
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Delgocitinib cream|DRUG: Delgocitinib cream vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effects of Home-based CIMT and Clinic-based CIM on Stroke
Status: RECRUITING
Conditions: Motor Function
Interventions: DEVICE: Home-based CIMT|DEVICE: Clinic-based CIMT|DEVICE: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
Status: COMPLETED
Conditions: Tobacco Use
Interventions: BEHAVIORAL: Newly developed warnings with images at 30% size|BEHAVIORAL: FDA proposed text-only warnings at 30% size
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Birds and Bees Research Study
Status: COMPLETED
Conditions: Sexual Behavior|Communication
Interventions: BEHAVIORAL: Web-based resource on adolescent sexual health|BEHAVIORAL: Alternate web-based resource on adolescent sexual health
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Pharmacokinetics and Potential Activity of HE3286 in Obese Adult Subjects
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: HE3286
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia
Interventions: DRUG: PEG Asparaginase at six weeks interval|DRUG: PEG Asparaginase at two weeks interval
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LIAISON NES Influenza (FLU) A/B, Respiratory Syncytial Virus (RSV), & Coronavirus Disease 2019 (COVID-19) in Symptomatic Patients in Australia
Status: NOT_YET_RECRUITING
Conditions: Influenza A|Influenza Type B|Coronavirus Disease 2019|Respiratory Syncytial Virus (RSV)|Adenovirus|Enterovirus|Para Influenza|Bordetella Parapertussis Infection|Bordetella Pertussis Infection, Respiratory|Chlamydia Pneumonia|Mycoplasma Pneumonia
Interventions: DIAGNOSTIC_TEST: LIAISON NES FLU A/B, RSV, & COVID-19|DIAGNOSTIC_TEST: LIAISON PLEX Respiratory Flex Assay
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Definition of Biomechanical Indices Measurable During Sport Movements for the Prevention of Primary and Secondary ACL Injury
Status: COMPLETED
Conditions: Sport Injury|Anterior Cruciate Ligament Injury|Biomechanical; Lesion
Interventions: OTHER: Biomechanical analysis with inertial sensors (XSENS) and motion capture (BTS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Propranolol in Adults and Adolescents With ASD and Predictors of Response
Status: WITHDRAWN
Conditions: Autism
Interventions: DRUG: Propranolol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
Status: RECRUITING
Conditions: Non Small Cell Lung Cancer|Esophageal Cancer|Gastric Cancer|Pancreatic Cancer|Hepatocellular Cancer|Colorectal Cancer
Interventions: DIAGNOSTIC_TEST: Test for circulating tumor cells, DNA alterations
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy and Safety of Toujeo® Versus Tresiba® in Insulin-Naive Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Antihyperglycemic Drug(s) ± GLP-1 Receptor Agonist
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin glargine, 300U/mL|DRUG: Insulin degludec, 100 U/mL|DRUG: Non-insulin anti-diabetic treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Prospective Trial for Laparoscopic vs Open Resection for Rectal Cancer
Status: UNKNOWN
Conditions: Rectal Cancer
Interventions: PROCEDURE: open rectal resection|PROCEDURE: laparoscopic rectal resection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning for Acute Ischemic Stroke
Status: RECRUITING
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder
Status: RECRUITING
Conditions: Obsessive-Compulsive Disorder
Interventions: DRUG: Troriluzole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of TQB3909 Tablets Combined With TQB3702 Tablets in Patients With Hematologic Malignancy
Status: NOT_YET_RECRUITING
Conditions: Hematologic Malignancy
Interventions: DRUG: TQB3909 tablets|DRUG: TQB3702 tablets
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pain Reduction in Maxillomandibular Surgery Using Maxillary and Mandibular Nerve Blocks
Status: COMPLETED
Conditions: Pain, Post Operative|Regional Anesthesia
Interventions: PROCEDURE: bilateral ultra-sound guided maxillary and mandibular nerve blocks|PROCEDURE: Infiltration of Lidocaine 1%
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Desmoplastic Melanoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Elastography|BIOLOGICAL: Pembrolizumab|PROCEDURE: Positron Emission Tomography|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease
Status: WITHDRAWN
Conditions: Primary Amyloidosis of Light Chain Type
Interventions: DEVICE: High Cut-off Hemodialysis|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Lercanidipine and Valsartan in Patients With Essential Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Lercanidipine + Valsartan|DRUG: Lercanidipine or Valsartan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluating Performance and Safety of the Medical Device Jalucomplex in the Treatment of Facial and Neck Tissue Defects
Status: COMPLETED
Conditions: Cicatrix|Lipodystrophy|Plaque
Interventions: DEVICE: Jalucomplex
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Danish Rct on Exercise Versus Arthroscopic Meniscal Surgery for Young Adults
Status: COMPLETED
Conditions: Tear of Meniscus of Knee
Interventions: PROCEDURE: Arthroscopic meniscal repair or resection|BEHAVIORAL: Exercise and education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Reduction of Aspiration Through Cohesive Thin Liquids (CTL) in Patients With Mild Oropharyngeal Dysphagia
Status: COMPLETED
Conditions: Dysphagia|Stroke
Interventions: OTHER: Cereal extract concentration 1|OTHER: Cereal extract concentration 2|OTHER: Cereal extract concentration 3|OTHER: Thicken up clear concentration 1|OTHER: Thicken up clear concentration 2|OTHER: Thicken up clear concentration 3
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Durvalumab Alone or in Combination With Novel Agents in Subjects With NSCLC
Status: COMPLETED
Conditions: Stage III Non-small Cell Lung Cancer|Unresectable
Interventions: DRUG: Durvalumab + Oleclumab|DRUG: Durvalumab|DRUG: Durvalumab + Monalizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prospective Study on DEXTENZA® Safety And Efficacy Following Concomitant MIGS and Cataract Surgery
Status: TERMINATED
Conditions: Glaucoma|Cataract
Interventions: DRUG: Dexamethasone Ophthalmic Insert|DRUG: Prednisolone Acetate 1% Oph Susp
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on the Efficacy of Treatment by Radiotherapy and Pembrolizumab in Newly Diagnosed Metastatic Head & Neck Cancers
Status: RECRUITING
Conditions: Squamous Cell Carcinoma of Head and Neck
Interventions: DRUG: Pembrolizumab|RADIATION: Loco-regional radiotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility and Effectiveness of a Mindfulness Program Delivered by Web to Patients During Hospitalization and Caregivers.
Status: RECRUITING
Conditions: Chronic Migraine; Multiple Sclerosis; Motoneuron Disease
Interventions: OTHER: no comparator - TAU (Treatment-as-usual)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Efficacy of Percussion Massage Therapy Applied to the Lower Extremity on Pain, Edema in Pregnant Women
Status: COMPLETED
Conditions: Pregnancy Complications|Edema Leg|Physiotherapy
Interventions: OTHER: percussion massage therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Killed Oral Cholera Vaccine in Infants
Status: UNKNOWN
Conditions: Cholera|Diarrhea|Vibrio Infections
Interventions: BIOLOGICAL: Bivalent killed oral cholera vaccine|BIOLOGICAL: Killed Escherichia coli K12 placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
Status: COMPLETED
Conditions: Parkinson's Disease|Cognitive Impairment|Dementia
Interventions: DRUG: Memantine|DRUG: Placebo Oral Tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study in Patients With Advanced Breast Cancer
Status: TERMINATED
Conditions: HER2-negative Breast Cancer|Advanced Breast Cancer|Hormone Receptor-positive Breast Cancer
Interventions: DRUG: Part 1|DRUG: Part 2|DRUG: Part 3
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Stereotactic Body Radiotherapy Combined With PD-1 Blockers for Locally Advanced or Locally Recurrent Pancreatic Cancer
Status: COMPLETED
Conditions: Stereotactic Body Radiotherapy|PD-1 Inhibitors|Pancreatic Cancer
Interventions: RADIATION: Stereotactic body radiotherapy (SBRT)|DRUG: PD-1 blocking antibody
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Enhanced Motor Recovery Using Serotonergic Agents in Stroke
Status: COMPLETED
Conditions: Patients With Chronic Stroke
Interventions: DRUG: SSRI|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Batroxobin Combined With Anticoagulation in Cerebral Venous Sinus Thrombosis
Status: UNKNOWN
Conditions: Cerebral Venous Sinus Thrombosis|Batroxobin
Interventions: DRUG: Batroxobin combined with low molecular weight heparin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Immunogenicity of a Sabin Inactivated Poliovirus Vaccine.
Status: COMPLETED
Conditions: Polio and Post-Polio Syndrome
Interventions: BIOLOGICAL: Three-dose regimen of high dosage investigational sIPV|BIOLOGICAL: Three-dose regimen of medium dosage investigational sIPV|BIOLOGICAL: Three-dose regimen of low dosage investigational sIPV|BIOLOGICAL: Three-dose regimen of commercialized sIPV|BIOLOGICAL: Three-dose regimen of commercialized IPV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of EGEN-001 Combined With Carboplatin and Docetaxel in Recurrent, Platinum-Sensitive, Ovarian Cancer
Status: COMPLETED
Conditions: Ovarian Neoplasms
Interventions: GENETIC: EGEN-001 (phIL-12-005/PPC)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Comparing Once Daily Dose of 900mg of TETA 4HCL Against Cuprior® (450mg Trientine Base, Twice Daily).
Status: COMPLETED
Conditions: Wilson's Disease
Interventions: DRUG: 900mg TETA 4HCl Once Daily Formulation|DRUG: 900mg TETA 4HCl Cuprior®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of n-Acetylcysteine Maintenance on Alcohol Effects
Status: COMPLETED
Conditions: Alcohol Use Disorder
Interventions: DRUG: Alcohol|DRUG: Placebos|DRUG: N-acetyl cysteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy, Immunogenicity and Safety of V503 in Chinese Women Aged 20-45 Years (V503-023)
Status: ACTIVE_NOT_RECRUITING
Conditions: Papillomavirus Infections
Interventions: DRUG: V503|DRUG: Gardasil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of tDCS on Auditory Hallucination, Insight, Neurocognitive Function and HRV in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Schizoaffective Disorder|Auditory Hallucination, Verbal|Neurocognitive Dysfunction|Autonomic Imbalance|Psychosocial Impairment|Quality of Life
Interventions: DEVICE: tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison Between the Therapeutic Affect of Intravitreal Diclophenac and Triamcinolone in Persistent Uveitic Cystoids Macular Edema
Status: UNKNOWN
Conditions: Uveitis|Cystoid Macular Edema
Interventions: DRUG: Diclophenac|DRUG: Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Are Exercise Capacity and Physical Fitness Related With Quality of Life, Physical Activity, Cognitive Health and Health Literacy in Dyslipidemia
Status: NOT_YET_RECRUITING
Conditions: Dyslipidemias
Interventions: DIAGNOSTIC_TEST: Exercise Capacity Assessment|DIAGNOSTIC_TEST: Physical Fitness Assessment|OTHER: Quality of Life Assessment|OTHER: Physical Activity Assessment|OTHER: Cognitive Health Assessment|OTHER: Health Literacy Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p