pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Safety and Efficacy of 18 mm Short Vitrectomy Probe for Pediatric Vitreoretinal Surgeries
Status: RECRUITING
Conditions: Retinopathy of Prematurity Both Eyes|Retinal Disease|Persistent Fetal Vasculature|Coats Disease|Coats Retinopathy|Familial Exudative Vitreoretinopathies|Vitreous Disorder|Vitreous Anomalies|Retinal Vascular Disorder
Interventions: DEVICE: Pars plana vitrectomy with a 18 mm short vitrector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Bicalutamide and RO4929097 in Treating Patients With Previously Treated Prostate Cancer
Status: TERMINATED
Conditions: Adenocarcinoma of the Prostate|Recurrent Prostate Cancer|Stage IV Prostate Cancer
Interventions: OTHER: placebo|DRUG: gamma-secretase/Notch signalling pathway inhibitor RO4929097|DRUG: bicalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of PI3K Inhibitors in Relapsed/Refractory Large Granular T Lymphocytic Leukemia
Status: COMPLETED
Conditions: Relapsed/Refractory Large Granular T Lymphocytic Leukemia
Interventions: DRUG: Linperlisib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Therapy With Fecal Microbiota Transplantation and Vedolizumab for Induction of Ulcerative Colitis
Status: RECRUITING
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Fecal microbiota transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Interest of a TEteleconsultation of a Psychological Support Nurse on Psychological Distress in Patients With a Primary Malignancy of the Central Nervous System
Status: RECRUITING
Conditions: Central Nervous System Cancer|Psychological Distress
Interventions: OTHER: Teleconsultation for psychological support
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Liposomal Doxorubicin and Docetaxel in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Metastatic Breast Cancer
Interventions: DRUG: Pegylated liposomal doxorubicin|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Single Dose Absorption, Distribution, Metabolism, and Excretion Study of [14C]-CORT113176 in Healthy Male Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: [14C]-CORT113176
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis
Status: TERMINATED
Conditions: Polymyositis|Dermatomyositis
Interventions: DRUG: BAF312|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy on Walking Ability of Electroacupuncture Therapy in Elderly Patients With Sarcopenia
Status: RECRUITING
Conditions: Sarcopenia
Interventions: DEVICE: electroacupuncture|BEHAVIORAL: Rehabilitation Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Systane Ultra in Post Menopausal Women With Dry Eye
Status: COMPLETED
Conditions: Post Menopausal Dry Eye Subjects
Interventions: OTHER: Systane Ultra Lubricant Eye Drops|OTHER: Sensitive Eyes Eye Drops (Bausch & Lomb)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sirolimus Eluting Stenting in Acute Myocardial Infarction
Status: UNKNOWN
Conditions: Myocardial Infarction
Interventions: PROCEDURE: Primary angioplasty in acute myocardial infarction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Budesonide Foam for Participants With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
Status: COMPLETED
Conditions: Proctitis|Proctosigmoiditis
Interventions: DRUG: Budesonide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Functionally Aligned vs Mechanical Axis Aligned Total Knee Arthroplasty
Status: UNKNOWN
Conditions: Osteoarthritis|Osteo Arthritis Knee
Interventions: PROCEDURE: Functionally Aligned Total Knee Arthroplasty|PROCEDURE: Mechanically Aligned Total Knee Arthroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)
Status: RECRUITING
Conditions: Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)
Interventions: DRUG: Ibrutinib|DRUG: Lenalidomide|DRUG: Methotrexate|DRUG: Rituximab|DRUG: Etoposide|DRUG: PEGylated recombinant human granulocyte colony
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase I/II Study of 5-Azacytidine With Ara-C in Patients With Relapsed/Refractory Acute Myelogenous Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)
Status: COMPLETED
Conditions: Acute Myelogenous Leukemia|Myelodysplastic Syndrome|Leukemia
Interventions: DRUG: Azacitidine|DRUG: Ara-C
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Study of Tenofovir Plus Telbivudine Versus Monotherapy With Either Drug in HBeAg Negative Chronic Hepatitis B Patients
Status: WITHDRAWN
Conditions: Chronic Hepatitis B
Interventions: DRUG: Tenofovir|DRUG: Telbivudine|DRUG: Tenofovir plus Telbivudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS)
Status: RECRUITING
Conditions: Multiple Sclerosis|Clinically Isolated Syndrome of Demyelination
Interventions: DRUG: Tysabri Injectable Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Branched Chain Amino Acid Plus Glucose Supplement Reduces Exercise-Induced Delayed Onset Muscle Soreness in College Females
Status: COMPLETED
Conditions: Exercise-induced Delayed Onset Muscle Soreness
Interventions: DIETARY_SUPPLEMENT: Branched Chain Amino Acid drink supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Optimization of Thoracic Aortic MRI Acquisition Sequences for the Quantification of Diagnostic-assisting Biomarkers
Status: NOT_YET_RECRUITING
Conditions: Healthy Volunteers
Interventions: OTHER: MRI calibration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Fish Oil on Surgery Pain After Knee Replacement Patients: Randomized, Prospective, Double Blind, Placebo Control Trial
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DIETARY_SUPPLEMENT: EPAX 6000 EE 1000mg (0.6 gr DHA+EPA)|DIETARY_SUPPLEMENT: Capsules (Placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Intuition vs. Deliberation in Medical Decision Making
Status: COMPLETED
Conditions: Decision Making About Life-sustaining Treatment in Patients With Serious Cardiac, Respiratory and Oncological Conditions Likely to Limit Life Expectancy
Interventions: BEHAVIORAL: Cognitive load|BEHAVIORAL: Deliberative instructions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: OTHER
Clinical trial: Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Status: RECRUITING
Conditions: Transthyretin Amyloidosis|ATTR-CM|ATTRv-PN|ATTR|ATTR-Mixed|hATTR
Interventions: DRUG: Treatment of transthyretin (ATTR) amyloidosis in observational study setting
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Telehealth Intervention Program for Older Adults
Status: UNKNOWN
Conditions: Depression, Anxiety|Cognitive Impairment|Stress
Interventions: BEHAVIORAL: Telehealth phone calls|OTHER: Volunteer of TIP-OA Program|OTHER: Stakeholder of TIP-OA Program
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: PANenteric Crohn's Capsule Versus Ileo-Colonoscopy and Scan Study
Status: TERMINATED
Conditions: Crohn Disease
Interventions: DIAGNOSTIC_TEST: PillCamTM Crohn's capsule|DIAGNOSTIC_TEST: Magnetic resonance enterography|PROCEDURE: Ileo-colonoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies
Status: COMPLETED
Conditions: Hodgkin's Disease|Non-Hodgkin's Lymphoma
Interventions: DRUG: Vorinostat|DRUG: Niacinamide|DRUG: Etoposide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: On the Impact of Common Sweetening Agents on Glucose Regulation, Cognitive Functioning and Gut Microbiota
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: OTHER: Sucrose|OTHER: Stevia glycosides|OTHER: saccharin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of Tazemetostat in Combination With HMPL-689 in Patients With Relapsed/Refractory Lymphoma
Status: RECRUITING
Conditions: Relapsed/Refractory Lymphoma
Interventions: DRUG: tazemetostat|DRUG: HMPL-689
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Drug Levels and Safety of Pegbelfermin in Healthy Overweight and Obese Chinese and Korean Participants
Status: WITHDRAWN
Conditions: Healthy Participants
Interventions: BIOLOGICAL: BMS-986036|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Efficacy and Safety of 0.1% Tacrolimus and 0.1% Mometasone Furoate for Adult Vitiligo
Status: UNKNOWN
Conditions: Vitiligo
Interventions: DRUG: tacrolimus ointment|DRUG: Mometasone furoate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Grape Consumption on Brain Metabolism and Neuropsychological Performance Over 1 Year
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DIETARY_SUPPLEMENT: Grape Powder|DIETARY_SUPPLEMENT: Placebo Powder
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation
Status: UNKNOWN
Conditions: Constipation|Childhood Acute Lymphoblastic Leukemia|Neurofibromatosis 1|Chronic Constipation With Overflow
Interventions: DIAGNOSTIC_TEST: 3D-Transit
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Early Recurrent Nasopharyngeal Cancer: the Effect of Surgery vs IMRT
Status: NOT_YET_RECRUITING
Conditions: Recurrent Nasopharyngeal Carcinoma
Interventions: PROCEDURE: endonasal endoscopic surgery|RADIATION: radiation therapy(IMRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double Blind, Placebo Controlled, Incomplete Block, Crossover, Dose Ranging Study to Evaluate the Dose Response of GSK573719 Administered Once or Twice Daily Over 7 Days in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK573719|DRUG: GSK573719|DRUG: GSK573719|DRUG: GSK573719|DRUG: GSK573719|DRUG: GSK573719|DRUG: Tiotropium|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia
Status: COMPLETED
Conditions: Addison Disease|Adrenal Hyperplasia Congenital
Interventions: DRUG: Solu-Cortef|DRUG: Cortef
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reversing Corticosteroid Induced Memory Impairment
Status: COMPLETED
Conditions: Memory Impairment
Interventions: DRUG: Lamotrigine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study in Advanced Parkinson's Disease Patients With Predictable Motor Fluctuations
Status: COMPLETED
Conditions: Parkinson's Disease|Motor Fluctuations
Interventions: DRUG: DM-1992|DRUG: Sinemet IR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Regulation of Postprandial Nitric Oxide Bioavailability and Vascular Function By Dairy Fat
Status: COMPLETED
Conditions: Prediabetes
Interventions: OTHER: Glucose|OTHER: Glucose with Whole Fat Milk|OTHER: Glucose with Non-fat Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Proteome-based Personalized Immunotherapy of Glioblastoma
Status: UNKNOWN
Conditions: Glioblastoma
Interventions: BIOLOGICAL: Dendritic vaccine, allogeneic hematopoietic stem cells, cytotoxic lymphocytes|BIOLOGICAL: Dendritic vaccine, autologous hematopoietic stem cells, cytotoxic lymphocytes
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children
Status: COMPLETED
Conditions: Schistosomiasis
Interventions: BIOLOGICAL: Sm14|DRUG: GLA-SE solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of Sofosbuvir and Ledipasvir From Magicbuvir Plus 90/400 mg Tablets (Magic Pharma, Egypt) Versus Harvoni 90/400 mg Tablets (Gilead Sciences, USA)
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Magicbuvir Plus|DRUG: Harvoni (fist dose)|DRUG: Harvoni (second dose)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC
Status: UNKNOWN
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: EGFR-TKI|RADIATION: whole brain radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estimating Average Vitamin A Requirements in Indonesian and American Women
Status: COMPLETED
Conditions: Vitamin A Deficiency
Interventions: DIETARY_SUPPLEMENT: Vitamin A supplement|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: UW-CTRI Triple Medication Smoking Cessation Study
Status: COMPLETED
Conditions: Smoking
Interventions: DRUG: Varenicline|DRUG: Nicotine Transdermal Patch|DRUG: Nicotine Mini
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Postoperative Antibiotics Following Primary and Secondary Breast Augmentation
Status: WITHDRAWN
Conditions: Surgical Site Infection|Capsular Contracture Associated With Breast Implant|Antibiotic Resistant Infection|Antibiotic Side Effect
Interventions: DRUG: Cefazolin|DRUG: Cephalexin|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy/Safety of CPI-613 in Combination With HD Cyt. and Mito. vs HD Cyt. and Mito. in Older Patients With R/R AML
Status: TERMINATED
Conditions: Relapsed/Refractory Acute Myeloid Leukemia
Interventions: DRUG: CPI-613 + High Dose Cytarabine and Mitoxantrone|DRUG: High Dose Cytarabine and Mitoxantrone|DRUG: Mitoxantrone, Etoposide and Cytarabine|DRUG: Fludarabine, Cytarabine, Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Status: UNKNOWN
Conditions: Infertility Female
Interventions: OTHER: In Vitro Maturation Procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors
Status: RECRUITING
Conditions: Solid Tumor, Adult
Interventions: BIOLOGICAL: GAd-209-FSP low dose|BIOLOGICAL: MVA-209-FSP low dose|BIOLOGICAL: GAd-209-FSP high dose|BIOLOGICAL: MVA-209-FSP high dose|BIOLOGICAL: GAd20-209-FSP, RP2D|BIOLOGICAL: MVA-209-FSP, RP2D|DRUG: KEYTRUDA®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Body Composition in Large for Gestational Age Infants (LGA) With Oral Feeding Difficulty
Status: RECRUITING
Conditions: Body Composition|Feeding; Difficult, Newborn|Nutrition Disorder, Infant
Interventions: OTHER: Dietary intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephropathy
Status: COMPLETED
Conditions: IgA Nephropathy
Interventions: DRUG: Prednisone or Prednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Therapeutic Educational Intervention and Fibromyalgia: a Mixed Methods Research
Status: RECRUITING
Conditions: Fibromyalgia
Interventions: BEHAVIORAL: Web-based Therapeutic Educational Intervention|OTHER: Conventional Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes Education/Skills Training and Social Needs Resolution Intervention
Status: RECRUITING
Conditions: Type 2 Diabetes
Interventions: BEHAVIORAL: DM Social Needs|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: How Does the Mood of the Patients Change Before and After the Invasive Urodynamic Study?
Status: NOT_YET_RECRUITING
Conditions: Lower Urinary Tract Symptoms|Mood Change|Diagnosis
Interventions: BEHAVIORAL: The State-Trait Anxiety Inventory (STAI)|BEHAVIORAL: Perceived Stress Scale|BEHAVIORAL: Visual Analog Scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study To Investigate The Antidepressant Effect Of Lamotrigine In Patients With Bipolar Disorder Using Lithium
Status: COMPLETED
Conditions: Bipolar Disorder|Bipolar Depression
Interventions: DRUG: lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Preparation and Feasibility of Exams for Expected Studies
Status: RECRUITING
Conditions: Healthy Volunteers|Parkinson's Disease Patients|Para/Tetraplegic Patients
Interventions: OTHER: CE marked Medical Device MagnetoEncephaloGraphy (MEG) usability|OTHER: CE marked Medical Device Magnetic Resonance Imaging (MRI) usability|OTHER: CE marked Medical Device ElectroEncephaloGraphy (EEG) usability|OTHER: CE marked Medical Device ElectroCardioGraphy (ECG) usability
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Gabapentin as an Adjunct to Perioperative Pain Management Regimens for Uterine Aspiration
Status: COMPLETED
Conditions: Other Abortion|Spontaneous Abortion
Interventions: DRUG: Gabapentin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
Status: COMPLETED
Conditions: Cesarean Delivery
Interventions: DRUG: Metoclopramide|DRUG: Phenylephrine infusion|DRUG: Combination Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epstein-Barr Virus-Specific Immunotherapy for Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: BIOLOGICAL: Epstein-Barr virus-specific adoptive T-cells immunotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration
Status: NOT_YET_RECRUITING
Conditions: Back Pain|Intervertebral Disc Degeneration
Interventions: PROCEDURE: Physical Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remote Dietary Counseling to Promote Healthy Diet and Blood Pressure
Status: COMPLETED
Conditions: Blood Pressure|High Blood Pressure|Dietary Modification|Overweight and Obesity
Interventions: BEHAVIORAL: Self-Guided Approach|BEHAVIORAL: Dietitian-led Approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Gabapentin on Spinal Anesthesia Duration
Status: COMPLETED
Conditions: Prolongation of Spinal Anesthesia
Interventions: DRUG: Gabapentin 300mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Self Fixating Versus Stapled Mesh for Laparoscopic Inguinal Hernia Repair
Status: RECRUITING
Conditions: Inguinal Hernia
Interventions: DEVICE: self-gripping mesh|DEVICE: Stapled mesh
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Peritonsillar Infiltration of Ketamine and Dexamethasone for Postoperative Pain Relief in Children Following Adenotonsillectomy
Status: UNKNOWN
Conditions: Tonsillectomy
Interventions: DRUG: saline|DRUG: Ketamine|DRUG: Dexamethasone|DRUG: ketamine-dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Sintilimab Plus Bevacizumab as Adjuvant Therapy in HCC Patients at High Risk of Recurrence After Curative Resection
Status: NOT_YET_RECRUITING
Conditions: HCC|Adjuvant Therapy|Immunotherapy
Interventions: DRUG: Sintilimab|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prospective Randomized Trial Comparing Standard Ligament Reconstruction Tendon Interposition (LRTI) VS Ligament Reconstruction Tendon Interposition (LRTI) With an Interference Screw for Thumb Carpometacarpal Arthritis - Pilot Study
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: PROCEDURE: LRTI|DEVICE: Biotenodesis Screw
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Systems Level Intervention for Unemployed Persons With Social Anxiety Disorder
Status: COMPLETED
Conditions: Social Anxiety Disorder
Interventions: BEHAVIORAL: Cognitive Behavioral Therapy Group|OTHER: Vocational Services as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of a Single Intramuscular Dose of Nirsevimab in the Prevention of Hospitalizations Due to Respiratory Syncytial Virus (RSV) Infection in Healthy Term and Preterm Infants During the First Year of Life
Status: ACTIVE_NOT_RECRUITING
Conditions: RSV Immunization|Healthy Volunteer
Interventions: BIOLOGICAL: Nirsevimab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Impact of Immuno-Oncologic Agent on Neoadjuvant Chemotherapy in Triple Negative Breast Cancer
Status: RECRUITING
Conditions: Triple Negative Breast Cancer|Neoadjuvant Chemotherapy|Pembrolizumab|Tumor Microenvironment
Interventions: GENETIC: Visium, Whole Genome Sequencing(WGS)/Whole Transcriptome Sequencing(WTS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Treatment Options for Acute Distal Radioulnar Joint Instability
Status: WITHDRAWN
Conditions: Wrist Injuries
Interventions: PROCEDURE: Serial casting/splinting|PROCEDURE: Percutaneous fixation|PROCEDURE: Foveal repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: MADIT-CRT LONG-TERM INTERNATIONAL FOLLOW-UP REGISTRY - EUROPE
Status: COMPLETED
Conditions: Heart Failure
Interventions: DEVICE: Patients that were randomized to the the cardiac resynchronization therapy with defibrillation (CRT-D) device for the study|DEVICE: MADIT-CRT ICD ONLY ARM
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: UTI Prophylaxis With Cranberry Extract After Female Incontinence Surgery
Status: COMPLETED
Conditions: Urinary Tract Infections|Incontinence
Interventions: DIETARY_SUPPLEMENT: Cranberry extract capsules|DIETARY_SUPPLEMENT: Placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of a Psycho-corporal Training on Postural and Cognitive Dual-task Performances in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: OTHER: Movement group
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Cardiac Arrhythmias in Hand Surgery Using Local Anesthesia With Adrenaline
Status: COMPLETED
Conditions: Evaluation of Cardiac Arrhythmias in Hand Surgery Using Local Anesthesia With Adrenaline
Interventions: PROCEDURE: Local anesthesia with lidocaine and adrenalin.|DRUG: lidocaine and adrenalin|DRUG: lidocaine and arterial blockage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effects of Hydrolysed Porcine Proteins on Muscle Protein Synthesis and Appetite
Status: COMPLETED
Conditions: Hunger|Satiety Response|Protein Synthesis
Interventions: DIETARY_SUPPLEMENT: Hydrolysed porcine protein from blood|DIETARY_SUPPLEMENT: Hydrolysed porcine protein from muscle|DIETARY_SUPPLEMENT: Hydrolysed whey protein
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Simulation-based Stress Inoculation Training Study for UK Medical Professionals
Status: ENROLLING_BY_INVITATION
Conditions: Stress|Stress, Psychological|Stress, Job
Interventions: BEHAVIORAL: Stress Inoculation Training|BEHAVIORAL: Alternative Training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: CrossBoss and Stingray Catheter and Entera Guidewire Chronic Total Occlusion (CTO) Study
Status: COMPLETED
Conditions: Coronary Artery Disease|Coronary Artery Chronic Total Occlusion
Interventions: DEVICE: BridgePoint Medical System (CrossBoss Catheter, Stingray Catheter, Entera Guidewire)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma
Status: RECRUITING
Conditions: Oropharyngeal Cancer|Supraglottic Squamous Cell Carcinoma|Hypopharyngeal Squamous Cell Carcinoma
Interventions: RADIATION: Intensity-Modulated Radiation Therapy (IMRT)|PROCEDURE: Trans Oral Surgery (TOS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Single Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-dose Dexamethasone (Pom/Dex) in Participants With Relapsed/Refractory Multiple Myeloma (RRMM)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Belantamab mafodotin|DRUG: Pom/dex (Pomalidomide plus low dose Dexamethasone)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sorafenib Plus Paclitaxel in Adreno-Cortical-Cancer Patients
Status: UNKNOWN
Conditions: Adrenocortical Carcinoma
Interventions: DRUG: Sorafenib|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lapatinib and Ixabepilone in Treating Patients With Advanced Solid Tumors
Status: TERMINATED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: ixabepilone|DRUG: lapatinib ditosylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: real-time fMRI neurofeedback: Amygdala|BEHAVIORAL: real-time fMRI neurofeedback: HIPS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Prospective Analysis of the Efficacy of Allosync Expand and Autograft Bone Graft in Open Lumbar Spinal Fusion
Status: ENROLLING_BY_INVITATION
Conditions: Spondylolisthesis, Grade 1
Interventions: DEVICE: Allosync Expand
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, and Immunogenicity of the Human Cytomegalovirus Vaccine (V160) in Healthy Adults (V160-001)
Status: COMPLETED
Conditions: Cytomegalovirus Infections
Interventions: BIOLOGICAL: V160 Low Dose IM|BIOLOGICAL: V160 Medium Dose IM|BIOLOGICAL: V160 High Dose IM|BIOLOGICAL: V160 Medium Dose plus Merck Aluminum Phosphate Adjuvant (MAPA) 225 µg /dose IM|BIOLOGICAL: V160 High Dose plus MAPA 225 µg /dose IM|BIOLOGICAL: V160 Maximum Dose IM|OTHER: Placebo IM|BIOLOGICAL: V160 Medium Dose ID|OTHER: Placebo ID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA)
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Anakinra (r-metHuIL-1ra)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Acetaminophen-ibuprofen Combination on the Postoperative Pain After Thyroidectomy
Status: RECRUITING
Conditions: Thyroid Disease
Interventions: DRUG: Acetaminophen|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Confirmation of a Pharmacodynamic Interaction Between Tropisetron and Paracetamol
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Tropisetron|DRUG: paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest
Status: RECRUITING
Conditions: Out-Of-Hospital Cardiac Arrest|Cardiac Arrest|Cardiac Arrhythmia|Ventricular Fibrillation|Ventricular Arrythmia|Pulseless Electrical Activity
Interventions: DEVICE: ER-REBOA catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Performance Evaluation of the LumiraDx Point of Care CRP Assay
Status: COMPLETED
Conditions: Inflammation|Infections|Tissue Injury
Interventions: DIAGNOSTIC_TEST: Venepuncture|DIAGNOSTIC_TEST: Fingerstick
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Long-term Efficacy and Safety Evaluation of Growth Hormone in Children in China(CGLS)
Status: RECRUITING
Conditions: Childhood Short Stature
Interventions: DRUG: Polvethylene glycol recombinant human growth hormone injection (PEG-rhGH) or recombinanthuman growth hormone injection (rhGH)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: WAVES for Mal de Debarquement Syndrome
Status: WITHDRAWN
Conditions: Mal de Debarquement Syndrome
Interventions: DEVICE: WAVES (Wobble-oscillator Auditory/Visual Excitatory Stimulation)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Safety and Efficacy of OMS643762 in Subjects With Huntington's Disease
Status: TERMINATED
Conditions: Huntington's Disease
Interventions: DRUG: OMS643762|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Contextual Coaching Versus Training Workshop for Assistants in Special Education.
Status: COMPLETED
Conditions: Disabled Persons|Caregiver
Interventions: BEHAVIORAL: contextual one-on-one coaching|BEHAVIORAL: Trainig workshop
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Surgeon Infiltration QL Block Comparison
Status: COMPLETED
Conditions: Quadratus Lumborum Block|Surgical Wound Infiltration
Interventions: DRUG: Liposomal Bupivicaine|PROCEDURE: QL Block
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Undiagnosed COPD and Asthma Population Study (UCAP)
Status: COMPLETED
Conditions: Asthma|COPD
Interventions: DRUG: Treatment strategy using evidence-based guidelines for asthma or COPD|BEHAVIORAL: Smoking Cessation|BEHAVIORAL: Participant Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Probiotics Stabilized With Cryoprotection Technology in Patients With Irritable Bowel Syndrome
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Probiotic|DIETARY_SUPPLEMENT: Maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Biomarkers as Predictors of COVID-19 Disease Progression in Recently Infected Chronic Haemodialysis Patients
Status: COMPLETED
Conditions: COVID-19 by SARS-CoV-2 Infection
Interventions: OTHER: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Interest of the Automated Management of Deep Neuromuscular Blockade Monitoring (CURATP)
Status: ENROLLING_BY_INVITATION
Conditions: Neuromuscular Blockade
Interventions: DEVICE: Monitorage by TOF/PTC|DEVICE: Monitorage by ATP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Safety, Tolerability, and Pharmacokinetics of Inhaled Virazole Administered Via Air-Jet Nebulizer in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: 50 mg/mL Virazole Inhalant Product|DRUG: 100 mg/mL Virazole Inhalant Product|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Weight-Bearing CT Periprosthetic Distal Knee Fractures
Status: NOT_YET_RECRUITING
Conditions: Periprosthetic Fracture Around Prosthetic Joint Implant Knee
Interventions: OTHER: Periprosthetic Fracture Knee Repaired CT Scans
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Utilization of iMRI for Transsphenoidal Resection of Pituitary Macroadenomas
Status: TERMINATED
Conditions: Pituitary Macroadenoma
Interventions: OTHER: intra-operative MRI|PROCEDURE: Transsphenoidal resection of pituitary macroadenoma
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.
Status: UNKNOWN
Conditions: Advanced Breast Cancer|Female Breast Cancer
Interventions: DRUG: FCN-437c,Fulvestrant,Goserelin acetate|DRUG: Placebo,Fulvestrant,Goserelin acetate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Diesel Exhaust Followed by Administration of Nasal Spray Flu Vaccine on Individuals With & Without Allergies
Status: COMPLETED
Conditions: Allergic Rhinitis
Interventions: OTHER: live attenuated influenza virus (LAIV) with clean air|OTHER: LAIV and diesel exhaust particles
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: The Effect of Chlorpromazine on Esophageal Sensitivity in Healthy Volunteers.
Status: UNKNOWN
Conditions: Esophageal Reflux
Interventions: DRUG: Chlorpromazine|DEVICE: Multimodal stimulation probe|DRUG: Placebo - Concentrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures
Status: COMPLETED
Conditions: Refractory Partial Seizures
Interventions: DRUG: perampanel|DRUG: perampanel|DRUG: perampanel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Study of Trilaciclib Combined With Chemotherapy On The Neoadjuvant Therapy of TNBC
Status: NOT_YET_RECRUITING
Conditions: Breast Neoplasm
Interventions: DRUG: Trilaciclib plus chemotherapy|DRUG: Chemotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Short-Course Radiation Therapy With Chemotherapy in People With Endometrial Cancer
Status: RECRUITING
Conditions: Endometrial Cancer|Stage III Endometrial Cancer|Stage III Endometrial Carcinoma|Endometrial Carcinoma|Endometrial Carcinoma Stage III
Interventions: RADIATION: Intensity-modulated radiation therapy|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Spinal Cord Stimulation Versus Instrumentation for FBSS
Status: RECRUITING
Conditions: Failed Back Surgery Syndrome|SCS|Neuromodulation|Spinal Cord Stimulation|Spinal Fusion|Low Back Pain
Interventions: DEVICE: Spinal Cord Stimulation|PROCEDURE: Spinal Fusion Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Impact of Antioxidant Juice Intake on Brain Injury and Placental Pathology in Infants With Intrauterine Growth Restriction (IUGR)
Status: COMPLETED
Conditions: Intrauterine Growth Restriction
Interventions: DIETARY_SUPPLEMENT: Pomegranate Juice|DIETARY_SUPPLEMENT: Placebo Juice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Clinical Usefulness of Virtual Antiarrhythmic Drug Test in Patients With Recurred AF After Catheter Ablation(CUVIA-AF3)
Status: RECRUITING
Conditions: Atrial Fibrillation
Interventions: DRUG: Virtual AAD TEST group|DRUG: Empirical AAD group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Probiotics in Infants With Gastroschisis
Status: COMPLETED
Conditions: Gastroschisis
Interventions: DIETARY_SUPPLEMENT: Bifidobacteria infantis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: To Investigate the Clinical Efficacy of an Experimental Toothpaste
Status: WITHDRAWN
Conditions: Gingivitis
Interventions: DRUG: isopropylmethylphenol and Fluoride|DRUG: Fluoride and Silica
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Status: UNKNOWN
Conditions: Brain Neoplasm|Intracranial Aneurysm|Cerebrovascular Moyamoya Disease
Interventions: PROCEDURE: Seldinger technique|PROCEDURE: Modified Seldinger technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Automated 3D Ultrasound-based Surveillance of Arteriovenous Fistula Maturation for Post-operative Hemodialysis Patients
Status: TERMINATED
Conditions: Arteriovenous Fistula|Arteriovenous Graft
Interventions: DEVICE: EchoMark/EchoSure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Fulness Trial (Fundus mUcosaL abLation aNd Endoscopic Sleeve Gastroplasty)
Status: RECRUITING
Conditions: Obesity
Interventions: PROCEDURE: Gastric Mucosal Ablation (GMA) of the fundus with Hybrid Argon Plasma Coagulation (HybridAPC) combined with Endoscopic Sleeve Gastroplasty (ESG)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of the Neuromuscular Blockade on Mask Ventilation
Status: COMPLETED
Conditions: Complication of Ventilation Therapy|Observation of Neuromuscular Block
Interventions: DRUG: Rocuronium 0.3 mg/kg|DRUG: Rocuronium 0.6 mg/kg|DRUG: Rocuronium 0.9 mg/kg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of 'Immuncell-LC Group' and 'Non-treatment Group' in Nexavar Treated Patients for Advanced HCC
Status: COMPLETED
Conditions: Advanced Hepatocellular Carcinoma
Interventions: DRUG: Immuncell-LC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Efficacy of a Virtual Reality Cognitive Remediation Program for People Living With Psychosis
Status: RECRUITING
Conditions: Psychotic Disorders|Schizophrenia|Schizo Affective Disorder
Interventions: BEHAVIORAL: Cognitive Remediation|BEHAVIORAL: Active Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT