pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Renal Assessment for Early Detection of Renal Impairment in Systemic Sclerosis and Systemic Lupus Erythematosus Patients
Status: NOT_YET_RECRUITING
Conditions: Systemic Sclerosis and Systemic Lupus Erythematous
Interventions: DEVICE: Renal multi-parametric MRI, Renal doppler ultrasound, Serum CD147
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of a Relaxation and Guided Imagery Intervention in School Context
Status: RECRUITING
Conditions: Mental Health Wellness 1|Positive and Negative Affect|Social Skills|Happiness|Self Esteem|Self-Regulation, Emotion|Anxiety|Cognitive Change|Heart Rate Variability|Stress, Psychological|Physical Activity
Interventions: OTHER: MindRegulation Intervention|OTHER: Relaxation|OTHER: Waiting List Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Latent Miofascial Trigger Points in the Vertical Jump in Female Voleyball Players
Status: UNKNOWN
Conditions: Sports Physical Therapy
Interventions: DEVICE: Dry Needling plus normal volleyball training|OTHER: Control Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between Hidradenitis Suppurativa and Spondyloarthritis
Status: COMPLETED
Conditions: Hidradenitis Suppurativa
Interventions: RADIATION: magnetic resonance imaging (MRI) of the sacro-iliac region HLA B27 test C-reactive protein (CRP) measurement
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Dietary Collagen Peptides and Periodontal Inflammation
Status: COMPLETED
Conditions: Gingivitis
Interventions: DIETARY_SUPPLEMENT: collagen peptide test|DIETARY_SUPPLEMENT: collagen peptide placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Sorafenib/ Carboplatin/ Paclitaxel in Patients With Solid Tumors
Status: COMPLETED
Conditions: Neoplasms
Interventions: DRUG: Nexavar (Sorafenib, BAY43-9006)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of an Oral Nutritional Supplement Containing AN777
Status: COMPLETED
Conditions: Malnutrition|Sarcopenia
Interventions: OTHER: medical food with AN777|OTHER: oral nutritional formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
Status: RECRUITING
Conditions: Bladder Cancer
Interventions: DRUG: Alvimopan|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: irinotecan hydrochloride|DRUG: temozolomide
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: TREATMENT
Clinical trial: Smoking Termination / Anxiety Reduction Treatment (ST/ART)
Status: COMPLETED
Conditions: Smoking|Anxiety Disorders
Interventions: DRUG: Nicotine Patch|BEHAVIORAL: Smoking Termination and Anxiety Reduction Treatment|BEHAVIORAL: Education-Supportive Psychotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Side Effects of High-Dose Intensity-Modulated Radiation Therapy in Treating Patients With Advanced Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Long-term Effects Secondary to Cancer Therapy in Adults|Oral Complications of Radiation Therapy|Radiation Toxicity
Interventions: PROCEDURE: adjuvant therapy|PROCEDURE: management of therapy complications|PROCEDURE: quality-of-life assessment|RADIATION: intensity-modulated radiation therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)
Status: ENROLLING_BY_INVITATION
Conditions: Stargardt Disease|Stargardt Macular Degeneration|Stargardt Macular Dystrophy|Autosomal Recessive Stargardt Disease 1 (ABCA4-related)
Interventions: DRUG: ALK-001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Block and Pain Management in Neurosurgery
Status: UNKNOWN
Conditions: Post Operative Pain|Craniofacial Pain
Interventions: DRUG: Sphenopalatine ganglion block|DRUG: Standard Preparation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Adapting Project UPLIFT for Hispanic Patients With Epilepsy II
Status: COMPLETED
Conditions: Epilepsy
Interventions: BEHAVIORAL: Using Practice and Learning to Increase Favorable Thoughts|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Foley Bulb With Oral Misoprostol for Induction of Labor
Status: COMPLETED
Conditions: Pregnancy|Labor, Induced
Interventions: OTHER: Foley bulb plus Oral Misoprostol|OTHER: Oral Misoprostol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: ED90 of Fospropofol Disodium in Induction and Maintenance of Anesthesia
Status: RECRUITING
Conditions: Elective Surgery
Interventions: DRUG: fospropofol
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ERAS Anesthetic Care for Metastatic Spine Cancer Resection
Status: UNKNOWN
Conditions: Metastatic Bone Tumor
Interventions: OTHER: ERAS anesthetic care|OTHER: Standard anesthetic care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Thalamic LFPs and VIM DBS in Essential Tremor: Correlation, Evolution, and Therapeutic Perspectives
Status: COMPLETED
Conditions: Essential Tremor
Interventions: DEVICE: Deep Brain Stimulation with Medtronic Activa PC+S systems
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: DisCoVisc Comparative Evaluation
Status: COMPLETED
Conditions: Cataracts
Interventions: DEVICE: DisCoVisc|DEVICE: DuoVisc|DEVICE: BioVisc|DEVICE: Healon5|DEVICE: Amvisc Plus
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of Auditory Brainstem Implant in Young Children
Status: WITHDRAWN
Conditions: Bilateral Cochlear Aplasia|Bilateral Cochlear Nerve Deficiency|Bilateral Cochlear Ossification Secondary to Meningitis
Interventions: DEVICE: Auditory brainstem implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
Status: COMPLETED
Conditions: Photodamaged Skin
Interventions: DRUG: Vitamin C with AHA Exfoliative Serum|DRUG: Placebo serum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: House Calls and Decision Support: Improving Access to Live Donor Transplantation
Status: COMPLETED
Conditions: Chronic Kidney Disease|End-Stage Renal Disease
Interventions: BEHAVIORAL: House Calls|BEHAVIORAL: Web-Based Patient-Centered Decision Support Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety and Efficacy of Remote Ischemic Conditioning Combined With Intravenous Thrombolysis for Acute Ischemic Stroke
Status: COMPLETED
Conditions: Acute Ischemic Stroke
Interventions: PROCEDURE: Remote ischemic conditioning|PROCEDURE: Sham remote ischemic conditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Oral Vitamin D Supplementation on the Prevention of Peritoneal Dialysis-related Peritonitis
Status: COMPLETED
Conditions: Peritoneal Dialysis-associated Peritonitis|Vitamin D Deficiency
Interventions: DRUG: Cholecalciferol (2000iu qd)|OTHER: Routine therapy for PD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effects of Continuous ESP Catheters on Recovery, Pain and Opioid Consumption After Multilevel Spine Surgery
Status: TERMINATED
Conditions: Post Operative Pain|Spine Surgery
Interventions: OTHER: Ropivacaine|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: OTHER
Clinical trial: Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Adnexal Carcinoma|Anaplastic Large Cell Lymphoma, ALK-Negative|Anaplastic Large Cell Lymphoma, ALK-Positive|Apocrine Carcinoma|Carcinoma Arising From Cylindroma|Carcinoma Arising From Spiradenoma|Digital Papillary Adenocarcinoma|Endocrine Mucin-Producing Sweat Gland Carcinoma|Extramammary Paget Disease|Extraocular Sebaceous Carcinoma|Hidradenocarcinoma|Keratoacanthoma|Malignant Sweat Gland Neoplasm|Merkel Cell Carcinoma|Microcystic Adnexal Carcinoma|NK-Cell Lymphoma, Unclassifiable|Papillary Adenocarcinoma|Porocarcinoma|Primary Cutaneous Mucinous Carcinoma|Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Recurrent T-Cell Non-Hodgkin Lymphoma|Refractory Anaplastic Large Cell Lymphoma|Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma|Refractory Merkel Cell Carcinoma|Refractory Mycosis Fungoides|Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma|Refractory Skin Squamous Cell Carcinoma|Refractory T-Cell Non-Hodgkin Lymphoma|Sezary Syndrome|Signet Ring Cell Adenocarcinoma|Skin Adenoid Cystic Carcinoma|Skin Basal Cell Carcinoma|Skin Basosquamous Cell Carcinoma|Skin Squamous Cell Carcinoma|Squamoid Eccrine Ductal Carcinoma|Squamous Cell Carcinoma of Unknown Primary|Sweat Gland Carcinoma|Trichilemmal Carcinoma|Vulvar Squamous Cell Carcinoma
Interventions: PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|PROCEDURE: Computed Tomography|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab|PROCEDURE: Positron Emission Mammography|BIOLOGICAL: Talimogene Laherparepvec
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of L. Reuteri NCIMB 30242 on Plasma Bile Acid Profile
Status: COMPLETED
Conditions: Hypercholesterolemia
Interventions: DIETARY_SUPPLEMENT: Delayed release capsule, L. reuteri NCIMB 30242, escalated dose|DIETARY_SUPPLEMENT: Standard vegetarian capsule, L. reuteri NCIMB 30242, escalated dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners
Status: COMPLETED
Conditions: Irritant Contact Dermatitis
Interventions: OTHER: Skin Testing of Hair cleansing products
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multi-Center Study of Naltrexone-Acetaminophen in Acute Migraine, With an Exploratory Analysis of Co-occurring Anxiety
Status: NOT_YET_RECRUITING
Conditions: Migraine
Interventions: DRUG: Naltrexone-Acetaminophen|DRUG: Naltrexone|DRUG: Acetaminophen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Possible Effects on the QT/ QTc Interval of Rupatadine in Healthy Volunteers
Status: COMPLETED
Conditions: Human Experimentation (Human Volunteers)
Interventions: DRUG: Rupatadine|DRUG: moxifloxacin|PROCEDURE: Continous electrocardiographic register|PROCEDURE: Pharmacokinetic profile
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: A Study of Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial Cancer
Status: COMPLETED
Conditions: Urothelial Carcinoma
Interventions: DRUG: Ramucirumab|DRUG: Docetaxel|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Prevalence of Abdominal Aortic Aneurysm in Patients Undergoing Coronary Angiography
Status: COMPLETED
Conditions: Coronary Angiography
Interventions: DEVICE: Abdominal ultra-sound|PROCEDURE: Abdominal ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects
Status: COMPLETED
Conditions: Pharmacokinetics
Interventions: DRUG: DAB|DRUG: SCY-078 plus DAB
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CHO-loading Before and High Intermittent CHO-intake During Physical Exercise in T1D
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: OTHER: Carbohydrate loading and high intermittent carbohydrate intake during physical exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Comparison of the Efficacy of Ultrasound Guided vs Non-guided Suprascapular Nerve Block Treatment in Stroke Patients
Status: RECRUITING
Conditions: Hemiplegia|Stroke
Interventions: DRUG: Ultrasound-guided Suprascapular Nerve Block|DRUG: Anatomical Landmark-guided Suprascapular Nerve Block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Combined Scaffolds and Sodium Hypochlorite in Regenerative Endodontics of Immature Teeth
Status: RECRUITING
Conditions: Incomplete Root Formation of Anterior Teeth
Interventions: OTHER: Intra-canal medication protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Enhancing Breast Milk Production With Domperidone in Mothers of Preterm Neonates
Status: COMPLETED
Conditions: Low Milk Supply
Interventions: DRUG: Domperidone maleate|DRUG: Placebo Tablet|DRUG: Domperidone maleate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Esketamine on Postoperative Depression、Gut Microbiota、Bispectral Index Data of Depression Patients Undergoing Breast Cancer Operation (ESPOD-BI)
Status: RECRUITING
Conditions: Depression
Interventions: DRUG: Esketamine|DRUG: Saline Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Bioequivalence of Ibrutinib 140 Milligram (mg) Tablet to 140 mg IMBRUVICA Capsule
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Ibrutinib|DRUG: IMBRUVICA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of ALF-5755 in Patients With Nonacetaminophen Severe Acute Hepatitis & Early Stage Acute Liver Failure
Status: UNKNOWN
Conditions: Liver Failure, Acute
Interventions: DRUG: ALF-5755|DRUG: Saline solution (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
Status: ACTIVE_NOT_RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|B Lymphoblastic Lymphoma|Down Syndrome
Interventions: DRUG: Asparaginase Erwinia chrysanthemi|BIOLOGICAL: Blinatumomab|DRUG: Cyclophosphamide|DRUG: Cytarabine|DRUG: Dexamethasone|DRUG: Doxorubicin Hydrochloride|DRUG: Leucovorin Calcium|DRUG: Mercaptopurine|DRUG: Mercaptopurine Oral Suspension|DRUG: Methotrexate|DRUG: Pegaspargase|DRUG: Prednisolone|DRUG: Prednisone|RADIATION: Radiation Therapy|RADIATION: Radiation Therapy|DRUG: Thioguanine|DRUG: Vincristine Sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Assessment of Iron Absorption From Aspergillus Oryzae
Status: COMPLETED
Conditions: Iron Bioavailability
Interventions: DRUG: Ferrous Sulfate|DIETARY_SUPPLEMENT: Aspiron
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Subcutaneous Aspart Insulin to Treat Diabetic Ketoacidosis (DKA) and Beta-Hydroxybutyrate Testing in DKA
Status: COMPLETED
Conditions: Diabetic Ketoacidosis
Interventions: DRUG: Insulin (Aspart Insulin [Novolog], Regular Insulin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances
Status: COMPLETED
Conditions: Acute Kidney Injury|Exercise-associated Hyponatremia|Perceived Exertion
Interventions: DRUG: Ibuprofen|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Sacha Inchi Oil Supplementation in 3Hs
Status: COMPLETED
Conditions: Endocrine and Metabolic Secondary Hypertension
Interventions: DIETARY_SUPPLEMENT: Sacha Inchi Oil softgel supplement|DIETARY_SUPPLEMENT: Corn oil softgel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Phase III of Gemcitabine Vs TS-1 Vs Gemcitabine Plus TS-1 in Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine plus TS-1|DRUG: TS-1|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
Status: COMPLETED
Conditions: Lateral Canthal Lines|Crow's Feet|Facial Wrinkles
Interventions: DRUG: Botulinum Toxin Type A|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial to Study the Safety Tolerability, Pharmacokinetics, Food Effect & Pharmacodynamics of a New Compound P7435 in Healthy, Overweight and/or Obese Subjects
Status: TERMINATED
Conditions: Healthy, Overweight and/or Obese Subjects
Interventions: DRUG: P7435
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Chronic Laryngitis With Amitriptyline
Status: TERMINATED
Conditions: Laryngeal Diseases
Interventions: DRUG: Amitriptyline|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS)
Status: RECRUITING
Conditions: Acute Respiratory Distress Syndrome|Bronchopulmonary Dysplasia|High Frequency Oscillation Ventilation
Interventions: DEVICE: HFOV|DEVICE: CMV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Absolute Bioavailability of a Single Oral Dose of Selexipag in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Subjects
Interventions: DRUG: Selexipag for intravenous use|DRUG: Selexipag for oral use
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Physical Exercise for Men With Andropause
Status: UNKNOWN
Conditions: Androgen Deficiency|Depressive Symptoms|Stress, Psychological|Abdominal Obesity|Testosterone Deficiency|Erectile Dysfunction
Interventions: OTHER: Concurrent training|DIETARY_SUPPLEMENT: Eurycoma longifolia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Mobile Application Supported Health Promotion Program on Obesity of Adolescents
Status: COMPLETED
Conditions: Adolescents|Mobile Application|School Health|Physical Activity|Nutrition Disorder, Child
Interventions: OTHER: Mobile application-based adolecent obesity education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options
Status: TERMINATED
Conditions: Traumatic Nerve Injury
Interventions: DEVICE: Hollow tube nerve conduit, synthetic or biosynthetic|OTHER: Processed Human Nerve Tissue
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 68Ga-PSMA-11 PET for the Diagnosis of Metastatic Castration Resistant Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Carcinoma|Stage IV Prostate Cancer AJCC v8|Stage IVA Prostate Cancer AJCC v8|Stage IVB Prostate Cancer AJCC v8
Interventions: DRUG: 68Ga-PSMA-11|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Monitoring Devices on Healthcare Provider Performance During Neonatal Resuscitation
Status: COMPLETED
Conditions: Prematurity
Interventions: DEVICE: Respiratory Function Monitor (RFM)|DEVICE: Cerebral Near-Infrared Spectroscopy (NIRS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Burden of Chronic Kidney Disease (CKD), Type 2 Diabetes Mellitus (T2DM), and Comorbid T2DM/CKD in Alberta, Canada
Status: COMPLETED
Conditions: Chronic Kidney Diseases|Type 2 Diabetes
Interventions: OTHER: Not applicable - this is a non-interventional, observational study.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: MK-8237 (SCH900237) Biomarker Study in Participants With Allergic Rhinitis or Rhinoconjunctivitis (MK-8237-009)
Status: COMPLETED
Conditions: Allergic Rhinitis|Allergic Rhinoconjunctivitis
Interventions: BIOLOGICAL: MK-8237|OTHER: Placebo|BIOLOGICAL: NAC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of Perioperative Outcome Between Monopolar and Bipolar Hysteroscopic Myomectomy
Status: RECRUITING
Conditions: Hysteroscopic Myomectomy
Interventions: PROCEDURE: Bipolar hysteroscopic myomectomy|PROCEDURE: Monopolar hysteroscopic myomectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Primary Operation in SYnchronous meTastasized InVasivE Breast Cancer
Status: COMPLETED
Conditions: Synchronous Metastasized Breast Cancer|Circulating Tumor Cells
Interventions: PROCEDURE: Surgery|PROCEDURE: Surgery on Demand
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Fallopian Tube Cancer|Peritoneal Neoplasms
Interventions: DRUG: Olaparib|DRUG: Tremelimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A New Psychotherapy Intervention for Older Cancer Patients
Status: RECRUITING
Conditions: Cancer
Interventions: BEHAVIORAL: Cancer and Aging: Reflections for Elders (CARE) Intervention|BEHAVIORAL: Social Work and Supportive Counseling (SWSC) Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Motivating Campus Change Study
Status: ACTIVE_NOT_RECRUITING
Conditions: Drinking Behavior
Interventions: BEHAVIORAL: Sequential Personalized Feedback Intervention Delivery|BEHAVIORAL: Simultaneous Personalized Feedback Intervention Delivery|BEHAVIORAL: Text Message Boosters
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Association Between Multiple Coagulation-related Factors and Lymph Node Metastasis in Patients With Gastric Cancer: A Retrospective Cohort Study
Status: RECRUITING
Conditions: Gastric Cancer Stage|Lymph Node Metastasis
Interventions: DIAGNOSTIC_TEST: coagulation-related factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Department of Defense Funded Multicenter Pilot Study
Status: COMPLETED
Conditions: Rotator Cuff Repair|Anterior Cruciate Ligament Reconstruction|Ankle Arthrodesis or Arthroplasty|Hallux Valgus Correction
Interventions: DEVICE: ACTIVE peripheral nerve stimulation with a percutaneously inserted lead and wearable stimulator (SPR Therapeutics, Cleveland, Ohio)|DEVICE: SHAM peripheral nerve stimulation with a percutaneously inserted lead and wearable SHAM stimulator (SPR Therapeutics, Cleveland, Ohio)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Medication for Functional Abdominal Pain in Children
Status: COMPLETED
Conditions: Functional Gastrointestinal Disorders
Interventions: DRUG: Amitriptyline|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stromal Cells for Degenerative Meniscus Injury
Status: COMPLETED
Conditions: Chronic Meniscal Injury
Interventions: DRUG: XCEL-M-ALPHA and standard rehabilitation|OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ParisK: Validation of Imaging Techniques
Status: COMPLETED
Conditions: Stroke|Atherosclerosis
Interventions: OTHER: Magnetic Resonance Imaging (MRI), Multidetector Computed Tomography (MDCT), Ultrasonography (US), Transcranial Doppler (TCD)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Status: COMPLETED
Conditions: Anesthetic Complication Spinal
Interventions: DRUG: Phenylephrine|DRUG: saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow
Status: RECRUITING
Conditions: SGA, Turner Syndrome, Noonan Syndrome, ISS
Interventions: DRUG: Somapacitan|DRUG: Norditropin®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Compare the Efficacy and Safety of HB1801 to Taxotere in Advanced Non-Small Cell Lung Cancer (NSCLC)
Status: RECRUITING
Conditions: Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Interventions: DRUG: HB1801|DRUG: Taxotere
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC
Status: RECRUITING
Conditions: Extensive-stage Small-cell Lung Cancer
Interventions: DRUG: serplulimab|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Etoposide|RADIATION: Thoracic radiation therapy (TRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dehydroepiandrosterone (DHEA) Intervention To Treat Ovarian Aging
Status: COMPLETED
Conditions: Infertility|Ovarian Aging|Diminished Ovarian Reserve (DOR)|Predicted Poor-responders
Interventions: DRUG: Dehydroepiandrosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Isotopic Distribution of Intraperitoneal Chemotherapy for Peritoneal Carcinomatosis of Ovarian Origin
Status: WITHDRAWN
Conditions: Ovarian Cancer
Interventions: DRUG: Intraperitoneal cisplatin with nanocis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of PRAX-114 in Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: PRAX-114|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess Adverse Events and Effectiveness of Intradermally Injected JUVÉDERM® VOLITE™ Gel Filler in Adult Participants in China For the Improvement of Skin Quality
Status: RECRUITING
Conditions: Skin Quality Deficit
Interventions: DEVICE: JUVÉDERM® VOLITE™|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Anesthesia and EEG Discontinuity in Infants
Status: NOT_YET_RECRUITING
Conditions: Anesthesia, General|Electroencephalography|Infant|Anesthesia, Inhalation
Interventions: PROCEDURE: EEG guided anesthesia|PROCEDURE: Conventional anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study of Gesture and Executive Functions in Children With High Intellectual Potential
Status: COMPLETED
Conditions: High Intellectual Potential|Children
Interventions: OTHER: clinical examination in neurology|OTHER: neuropsychological examination|OTHER: anamnestic elements
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Ejiao Compound in the Treatment of Postpartum Anemia of Qi-blood Deficiency Syndrome
Status: UNKNOWN
Conditions: Postpartum Anemia
Interventions: DRUG: Ejiao compound|DRUG: Niferex
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of the Transcatheter Aortic Valve Implantation System With a Prospective, Multi-Center, One-Arm Approach to Evaluate the Efficacy and Safety in the Treatment of Patients With Severe Aortic Stenosis
Status: NOT_YET_RECRUITING
Conditions: Aortic Stenosis
Interventions: DEVICE: Transcatheter Aortic Valve Implantation (KOKA-VALVE)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of Proteoglycan F in the Treatment of Knee Osteoarthritis
Status: COMPLETED
Conditions: Primary Osteoarthritis of Knee Nos
Interventions: DIETARY_SUPPLEMENT: Proteoglycan F|OTHER: Placebo product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Ozonated Water on Pain, Swelling, Trismus and Quality of Life in Third Molar Surgery
Status: COMPLETED
Conditions: Ozone|Third Molar|Clinical Trial
Interventions: PROCEDURE: ozone|PROCEDURE: water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketone Esters for Optimization of Cognitive Performance in Hypoxia
Status: UNKNOWN
Conditions: Hypoxia|Ketosis
Interventions: DIETARY_SUPPLEMENT: Ketone Ester|DIETARY_SUPPLEMENT: Taste Matched Placebo|OTHER: Hypoxic exposure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Pexacerfont (BMS-562086) in the Treatment of Outpatients With Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: DRUG: pexacerfont|DRUG: escitalopram|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison Study of Three Standard Elbow Wrist Hand Orthoses to Limit Forearm Rotation
Status: COMPLETED
Conditions: Healthy
Interventions: DEVICE: Hely & Weber MTC Fracture Brace|DEVICE: Thermoplastic orthosis|DEVICE: Delta cast orthosis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Phase I Clinical, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: Donepezil patch|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection
Status: COMPLETED
Conditions: Colorectal Surgery|Surgical Wound Infection
Interventions: DRUG: gentamicin-collagen sponge dipped in saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy Of Amber Peripheral Liquid Embolic System
Status: ACTIVE_NOT_RECRUITING
Conditions: Vascular Anomalies|Hemorrhage|Aneurysm|Pseudoaneurysm|Varicose Veins|Portal Vein Embolization|Hypervascular Tumor|Type II Endoleak|Pathological Organ
Interventions: DEVICE: amber SEL-P Peripheral Liquid Embolic System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of a Nutritional Supplement on Post Prandial Glucose and Lipids in an Adult Population
Status: COMPLETED
Conditions: Impaired Fasting Glucose
Interventions: DIETARY_SUPPLEMENT: 25% fibre|DIETARY_SUPPLEMENT: 0% fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Locobase® REPAIR Used as an Adjunctive to Standard Therapy in Children With Moderate to Severe Atopic Dermatitis
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Locobase® REPAIR
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence
Status: COMPLETED
Conditions: Vulvar Cancer|Vulvar Intraepithelial Neoplasia
Interventions: BEHAVIORAL: standardized care (Intervention I)|BEHAVIORAL: Standardized care + WOMAN-PRO II program (Intervention II)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Status: COMPLETED
Conditions: Graft vs Host Disease|Hematopoietic Stem Cell Transplantation
Interventions: DRUG: Sitagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Detection of Anastomotic Leakage After Esophageal Surgery
Status: COMPLETED
Conditions: Esophageal Cancer|Anastomotic Leakage
Interventions: PROCEDURE: Contrast swallow radiography, endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: 3-D Transcranial Ultrasound Analysis Study
Status: COMPLETED
Conditions: Cerebrovascular Accident|Intracranial Hypertension
Interventions: DEVICE: 3-D ultrasound scanner|DRUG: Perflutren Protein-Type A Microspheres for injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Minimally Invasive Esophagectomy (MIE) in Prone Versus Left Decubitus Position
Status: UNKNOWN
Conditions: Esophageal Cancer|Esophagectomy
Interventions: PROCEDURE: thoracoscopic esophagectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparing the Effect of Video-cases and Text-cases on Medical Students' Learning in Tutorial
Status: COMPLETED
Conditions: Education, Medical|Education, Medical, Undergraduate|Problem-based Learning|Problem Solving|Interactive Tutorial
Interventions: BEHAVIORAL: video case modality|BEHAVIORAL: Text case modality
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Ziprasidone Switching in Response to Adherence and Psychotropic-Related Weight Gain Concerns Among Patients With Bipolar Disorder (Zip Ad)
Status: COMPLETED
Conditions: Medication Adherence|Bipolar Disorder
Interventions: DRUG: ziprasidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis
Status: COMPLETED
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Canakinumab (investigational)|DRUG: Placebo|DRUG: Methotrexate (MTX)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Safety and Efficacy of BGT007H Cell Therapy in Patients With Relapsed/Refractory Pancreatic Cancer
Status: RECRUITING
Conditions: Tumor Pancreas
Interventions: DRUG: BGT007H Cell Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Status: TERMINATED
Conditions: Recurrent Lung Non-Small Cell Carcinoma|Stage III Lung Non-Small Cell Cancer AJCC v7|Stage IIIA Lung Non-Small Cell Cancer AJCC v7|Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions: RADIATION: 3-Dimensional Conformal Radiation Therapy|DRUG: Carboplatin|RADIATION: Image Guided Radiation Therapy|RADIATION: Intensity-Modulated Radiation Therapy|OTHER: Laboratory Biomarker Analysis|DRUG: Paclitaxel|OTHER: Pharmacological Study|DRUG: Trametinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel and Nortriptyline Hydrochloride in Treating Patients With Relapsed Small Cell Carcinoma
Status: COMPLETED
Conditions: Small Cell Carcinoma
Interventions: DRUG: Nortriptyline Hydrochloride|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Status: TERMINATED
Conditions: Recurrent Adult Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: alemtuzumab|DRUG: asparaginase|DRUG: methotrexate|DRUG: dexamethasone|DRUG: leucovorin calcium|DRUG: mercaptopurine|DRUG: vincristine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Oral Contraceptive Pills Versus Expectant Management for Retained Pregnancy Products
Status: UNKNOWN
Conditions: Retained Products of Conception Post Abortion
Interventions: DRUG: Oral contraceptive|OTHER: Expectant management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of Insulin Detemir Compared With That of NPH Insulin in Subjects With Type 1 Diabetes.
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 1
Interventions: DRUG: Insulin detemir|DRUG: NPH insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: A Multicenter, Postmarketing Study Evaluating the Concentration of Cimzia® in Mature Breast Milk of Lactating Mothers
Status: COMPLETED
Conditions: Axial Spondyloarthritis (AxSpA)|Non-radiographic Evidence-AxSpA|Ankylosing Spondylitis|Crohn's Disease|Psoriatic Arthritis|Rheumatoid Arthritis
Interventions: PROCEDURE: Breast milk sampling|BIOLOGICAL: Certolizumab Pegol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Influence of Intrauterine Growth Restriction on Amplitude-integrated EEG in Preterm Infants
Status: UNKNOWN
Conditions: Intrauterine Growth Restriction|Premature - Weight 1000g-2499g or Gestation of 28-37weeks|Neurodevelopmental Disorder|EEG; Spikes, Centrotemporal, Epilepsy of Childhood
Interventions: OTHER: aEEG
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
Status: TERMINATED
Conditions: Brain and Central Nervous System Tumors|Childhood Germ Cell Tumor|Extragonadal Germ Cell Tumor|Kidney Cancer|Liver Cancer|Lymphoma|Neuroblastoma|Ovarian Cancer|Sarcoma|Testicular Germ Cell Tumor|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: carboplatin|DRUG: dasatinib|DRUG: etoposide phosphate|DRUG: ifosfamide|GENETIC: microarray analysis|GENETIC: western blotting|OTHER: immunohistochemistry staining method|OTHER: laboratory biomarker analysis|PROCEDURE: therapeutic conventional surgery|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of DC-CTL Combined With CIK for Advanced Solid Tumor
Status: UNKNOWN
Conditions: Colorectal Cancer|Renal Cell Carcinoma|Nasopharyngeal Carcinoma|Lung Cancer
Interventions: BIOLOGICAL: Cytokine-induced Killer Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer
Status: RECRUITING
Conditions: Serplulimab,Gastric Cancer, Adjuvant Therapy
Interventions: DRUG: Serplulimab|DRUG: Docetaxel|DRUG: S1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Issues of Peribulbar Injection of UC-MSC in Patients With Retinitis Pigmentosa
Status: COMPLETED
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: Umbilical Cord Mesenchymal Stem Cell (UC-MSC)|BIOLOGICAL: Conditioned Medium (CM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: LUX-Breast 2; Afatinib in HER2 (Human Epidermal Growth Factor Receptor)-Treatment Failures
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: Vinorelbine 25 mg/m2 weekly|DRUG: Afatinib 40mg once daily (OD)|DRUG: Paclitaxel 80 mg/m2 weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sitagliptin Combined With Gemcitabine and Albumin-bound Paclitaxel in PDAC Patients
Status: NOT_YET_RECRUITING
Conditions: PDAC - Pancreatic Ductal Adenocarcinoma
Interventions: DRUG: Combination of sitagliptin+ gemcitabine + nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT