pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Lucentis Utilizing Visudyne (LUV Trial) Combination Therapy in the Treatment of Age-Related Macular Degeneration
Status: TERMINATED
Conditions: Age-Related Macular Degeneration
Interventions: DRUG: Ranibizumab (Lucentis)|DRUG: 0.5mg ranibizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Prevention of Oral Mucositis After Using Oral Topical Vitamin E Versus Voriconazole and Levofloxacin in Pediatric Cancer Patients Receiving Chemotherapy
Status: UNKNOWN
Conditions: Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Interventions: DIETARY_SUPPLEMENT: oral topical vitamin E
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Pilot Study to Evaluate Efficacy of Botanical Extracts as Protein Amplifier for Skeletal Muscle Strength & Growth.
Status: COMPLETED
Conditions: Muscle Strength
Interventions: OTHER: Placebo without Exercise|OTHER: Placebo with Exercise|OTHER: IP I|OTHER: IP II|OTHER: IP III
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Mindfulness Training for Smoking Cessation
Status: COMPLETED
Conditions: Cigarette Smoking|Tobacco Smoking|Nicotine Dependence|Smoking Cessation
Interventions: BEHAVIORAL: Mindfulness Training|BEHAVIORAL: Smoking Cessation Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Repetitive Transcranial Magnetic Stimulation as an Adjunct to Modified Constraint Induced Movement Therapy in Improving Upper Limb Function in Children With Hemiparetic Cerebral Palsy Aged 5 - 18 Years
Status: UNKNOWN
Conditions: Hemiparetic Cerebral Palsy
Interventions: DEVICE: mCIMT with real rTMS|DEVICE: mCIMT with sham rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety and Tolerability of Using the SHR-1210 by Advanced Solid Tumor Subjects
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: BIOLOGICAL: SHR-1210
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Compare Between Combimed Metformin-letrozole and Ovarian Drilling in Pcos With Bilateral Ovarian Drilling in Clomiphene-resistant Infertile Women With Polycystic Ovarian Syndrome
Status: COMPLETED
Conditions: Focus of Study
Interventions: DRUG: metformin plus letrozole|PROCEDURE: ovarian drilling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: INR-Triggered Transfusion In GI Bleeders From ER
Status: TERMINATED
Conditions: Respiratory Distress Syndrome, Adult|Gastrointestinal Hemorrhage|Liver Diseases|Transfusion Related Lung Injury
Interventions: OTHER: Transfuse plasma to High INR target|OTHER: Transfuse plasma to Low INR target
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: mRNA-1030|BIOLOGICAL: mRNA-1020|BIOLOGICAL: mRNA-1010|BIOLOGICAL: Active Comparator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Efficacy of Nepafenac 0.1% and Nepafenac 0.3 % on Pain Associated With Intravitreal Injections
Status: COMPLETED
Conditions: Pain
Interventions: DRUG: Nepafenac 0.1% Oph Susp|DRUG: Nepafenac 0.3% Oph Susp|DRUG: Artificial tear
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo
Status: NOT_YET_RECRUITING
Conditions: Vertigo, Peripheral
Interventions: DRUG: Diazepam 5mg|DRUG: Diazepam 10 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Etanercept and Vascular Function in Psoriasis
Status: COMPLETED
Conditions: PSORIASIS
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Flu Vaccine Trial in Bamako, Mali
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Inactivated Influenza Vaccine Trivalent Types A and B|BIOLOGICAL: Meningococcal Polysaccharide-Diphtheria Toxoid Conjugate Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effects of Oxytocin Administration to Patients and Therapists on Physiological Synchronization
Status: RECRUITING
Conditions: Severe Mental Illness
Interventions: DRUG: Intranasal Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Microcurrent Therapy After Eccentric Exercise
Status: COMPLETED
Conditions: Delayed Onset Muscle Soreness
Interventions: DEVICE: Microcurrent Therapy|DEVICE: Sham microcurrent therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy Trial of the Kids in Transition to School (KITS) Program for Children With Developmental Disabilities and Behavioral Problems
Status: COMPLETED
Conditions: School Readiness
Interventions: BEHAVIORAL: KITS Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects and Mechanism of Pretreatment With Dexmedetomidine to Etomidate Induce Myoclonus
Status: UNKNOWN
Conditions: Myoclonus
Interventions: DRUG: Low-dose Dexmedetomidine|DRUG: High-dose dexmedetomidine|DRUG: normal saline|DRUG: Etomidate|DRUG: midazolam，fentanyl，rocuronium|DRUG: propofol，remifentanil，cis atracurium
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Pro-Resolving Mediators in Acute Inflammation in Humans
Status: COMPLETED
Conditions: Inflammation; Skin|Resolution|Blister
Interventions: DRUG: Lovaza|OTHER: Cantharone|OTHER: Phlebotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Remineralization Effect of βTricalcium Phosphate Nanoparticles Versus FunctionalizedβTricalcium Phosphate Nanoparticles
Status: COMPLETED
Conditions: White Spot Lesions[Initial Caries]on Smooth Surface of Tooth
Interventions: OTHER: Functionalized Nano ᵦ tricalcium phosphate particles|OTHER: Nano ᵦ tricalcium phosphate particles|OTHER: sodium fluoride mouth wash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis
Status: UNKNOWN
Conditions: Spondylitis|Tuberculosis
Interventions: DIETARY_SUPPLEMENT: 400 IU|DIETARY_SUPPLEMENT: 5000 IU|DIETARY_SUPPLEMENT: 10000 IU|DRUG: Fixed Drug Combination
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Healthy Beat Acupunch on Physical Fitness of Thai Older Adults in Residential Homes
Status: RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: Healthy Beat Acupunch Regimen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction
Status: COMPLETED
Conditions: Acute Kidney Injury
Interventions: DRUG: Aminophylline|DRUG: Hydration plus N-acetylcisteine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Hsp90 Inhibitor AUY922 and Erlotinib Hydrochloride in Treating Patients With Stage IIIB-IV Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Adenocarcinoma of the Lung|Non-small Cell Lung Cancer
Interventions: DRUG: erlotinib hydrochloride|DRUG: Hsp90 inhibitor AUY922|OTHER: laboratory biomarker analysis|PROCEDURE: needle biopsy|GENETIC: mutation analysis|OTHER: pharmacological study
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome
Status: COMPLETED
Conditions: Polycystic Ovary Syndrome|Infertility, Female
Interventions: DEVICE: AblaCare System
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: EC905 Pharmacokinetic Profile Study
Status: COMPLETED
Conditions: Phase 1|Healthy|Benign Prostatic Hyperplasia|Lower Urinary Tract Symptoms
Interventions: DRUG: Tamsulosin HCl|DRUG: Solifenacin Succinate|DRUG: EC905
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Efficacy of Intravenous Lidocaine in the Operative Management of Thyroid Surgery With Intraoperative Nerve Monitoring
Status: UNKNOWN
Conditions: Thyroidectomy|Nerve Monitoring
Interventions: DRUG: Lidocaine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Immunogenicity of Three Seasonal Trivalent Influenza Vaccines in China Military
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: Seasonal trivalent influenza vaccine, Anflu®|BIOLOGICAL: Seasonal trivalent influenza vaccine, VAXIGRIP|BIOLOGICAL: Seasonal trivalent influenza vaccine, Fluarix
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: New Frontiers on Bariatric Surgical Procedures: Classical Bypass for Type-2 Diabetic Patients With Obesity Grade I
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2|Insulin Resistance|Obesity
Interventions: PROCEDURE: Roux-en-Y Bypass Gastroplasty
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial of SBIRT Services in School-based Health Centers
Status: COMPLETED
Conditions: Marijuana Use|Alcohol Consumption|Unsafe Sex|Risk Behavior
Interventions: BEHAVIORAL: Brief in-person motivational intervention|BEHAVIORAL: Computerized Brief Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Implantation of an Auditory Brainstem Implant for the Treatment of Incapacitating Unilateral Tinnitus
Status: RECRUITING
Conditions: Tinnitus
Interventions: DEVICE: Auditory brainstem implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety of Extending The Routine Flushing Of Implanted Port Devices From 4 Weeks To 12
Status: RECRUITING
Conditions: Maintenance of Implanted Port Devices
Interventions: DEVICE: Reduced IPD Flush Schedule|DEVICE: Standard IPD Flush Schedule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Erlotinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Status: COMPLETED
Conditions: Lung Cancer
Interventions: DRUG: Carboplatin|DRUG: erlotinib hydrochloride|DRUG: Paclitaxel|DRUG: erlotinib hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Integrated Neuromuscular Inhibition Technique in Combination With Therapeutic Exercise on Patients With Chronic Mechanical Neck Pain
Status: COMPLETED
Conditions: Neck Pain
Interventions: OTHER: Exercise programme|OTHER: Integrated Neuromuscular Inhibition Technique application.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin
Status: COMPLETED
Conditions: Cancer Survivor|Healthy Subject|Stage I Colorectal Cancer|Stage IA Breast Cancer|Stage IB Breast Cancer|Stage IIA Breast Cancer|Stage IIA Colorectal Cancer|Stage IIB Breast Cancer|Stage IIB Colorectal Cancer|Stage IIC Colorectal Cancer|Stage IIIA Breast Cancer|Stage IIIA Colorectal Cancer|Stage IIIB Breast Cancer|Stage IIIB Colorectal Cancer|Stage IIIC Breast Cancer|Stage IIIC Colorectal Cancer
Interventions: OTHER: Educational Intervention|OTHER: Internet-Based Intervention|DEVICE: Monitoring Device|OTHER: Quality-of-Life Assessment|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: Code Sepsis protocol (full implementation)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: flutamide|DRUG: goserelin|DRUG: leuprolide acetate|RADIATION: low-LET photon therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Angiotensin 1-7 in Obesity Hypertension
Status: TERMINATED
Conditions: Obesity|Hypertension
Interventions: DRUG: Angiotensin-(1-7)|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Measurement of the Effect of Positional Changes on Cerebral Oxygenation in Preterm Infants
Status: COMPLETED
Conditions: pOSitional Changes of Premature Infants
Interventions: DEVICE: Device: near infrared spectroscopy: INVOS 5100|DEVICE: invos 5100
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Antibiogram and Outcomes of Antimicrobial Regimens in Microbial Keratitis: A Prospective Cohort Study
Status: COMPLETED
Conditions: Bacterial Keratitis|Fungal Keratitis|Mixed Bacterial and Fungal Keratitis|Microbial Keratitis
Interventions: DRUG: Moxifloxacin Ophthalmic 0.5% Ophthalmic Solution|DRUG: Ceftazidime 5% + vancomycin 5%|DRUG: Gentamicin 1.4% + vancomycin 5%|DRUG: Natamycin 5% Oph Susp|DRUG: Voriconazole 1%|DRUG: Natamycin 5% + voriconazole 1%|DRUG: Natamycin 5%+ ceftazidime 5% + vancomycin 5%|DRUG: Voriconazole 1% + ceftazidime 5% + vancomycin 5%
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Isotonic Saline As Irrigation Fluid In Transurethral Resection of Prostate (TUR-P) Operations
Status: UNKNOWN
Conditions: Hyperchloremic Acidosis|Transurethral Resection of Prostate|Normal Anion Gap Metabolic Acidosis|Anesthesia
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: IL6&8 in Malnourished Children With Acute Diarrhea
Status: UNKNOWN
Conditions: Acute Diarrhea|Severe Acute Malnutrition|Acute Gastroenteritis
Interventions: DIAGNOSTIC_TEST: Evaluation of serum levels of IL-6 and IL-8
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors
Status: RECRUITING
Conditions: MSI-H/dMMR Solid Tumors
Interventions: DRUG: Tislelizumab (BGB-A317)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo in Patients With Bladder Cancer
Status: COMPLETED
Conditions: Urologic Neoplasms|Metastatic Bladder Cancer|Urinary Tract Neoplasms
Interventions: DRUG: OGX-427 600 mg|DRUG: OGX-427 1000 mg|DRUG: Placebo|DRUG: Gemcitabine|DRUG: Cisplatin|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
Status: RECRUITING
Conditions: Melanoma Stage IIIB/C
Interventions: DRUG: Daromun|PROCEDURE: Surgery|DRUG: Adjuvant therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease
Status: COMPLETED
Conditions: Health Volunteers, Huntington Disease
Interventions: DRUG: pridopidine (90 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: BIA-Guided Dry Weight Assessment on Sleep Quality in Chronic Hemodialysis Patients
Status: COMPLETED
Conditions: Renal Failure Chronic Requiring Hemodialysis|Poor Quality Sleep
Interventions: DEVICE: BIA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Randomized Clinical Trial of Intensive Computer-based Cognitive Remediation in Recent-onset Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: BEHAVIORAL: Neuroadaptive cognitive training|BEHAVIORAL: Computer games
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Capecitabine and Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer
Interventions: DRUG: capecitabine|DRUG: oxaliplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer
Status: COMPLETED
Conditions: Anatomic Stage 0 Breast Cancer AJCC v8|Anatomic Stage I Breast Cancer AJCC v8|Anatomic Stage IA Breast Cancer AJCC v8|Anatomic Stage IB Breast Cancer AJCC v8|Anatomic Stage II Breast Cancer AJCC v8|Anatomic Stage IIA Breast Cancer AJCC v8|Anatomic Stage IIB Breast Cancer AJCC v8|Early-Stage Breast Carcinoma|Estrogen Receptor Negative|HER2/Neu Negative|Progesterone Receptor Negative|Prognostic Stage 0 Breast Cancer AJCC v8|Prognostic Stage I Breast Cancer AJCC v8|Prognostic Stage IA Breast Cancer AJCC v8|Prognostic Stage IB Breast Cancer AJCC v8|Prognostic Stage II Breast Cancer AJCC v8|Prognostic Stage IIA Breast Cancer AJCC v8|Prognostic Stage IIB Breast Cancer AJCC v8|Triple-Negative Breast Carcinoma
Interventions: DRUG: Celecoxib|DRUG: Cyclophosphamide|DRUG: Doxorubicin|DRUG: Doxorubicin Hydrochloride|DRUG: Paclitaxel|BIOLOGICAL: Recombinant Interferon Alfa-2b|DRUG: Rintatolimod
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Utility of Neutrophil Gelatinase-associated Lipocalin (NGAL) in Predicting Renal Impairment, Further Decompensation and Rehospitalization in Acutely Decompensated and Chronic Heart Failure Patients
Status: COMPLETED
Conditions: Heart Failure
Interventions: OTHER: NGAL kit
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Impact of Modified Wheat Bran on Carbohydrate Fermentation in the Colon in Healthy and Obese Subjects
Status: COMPLETED
Conditions: Healthy|Obese
Interventions: DIETARY_SUPPLEMENT: Wheat bran|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Using "Decision Aids" to Help the Infant Family to Decide the Use of Oral Rotavirus Vaccine
Status: UNKNOWN
Conditions: Rotavirus Vaccines
Interventions: OTHER: Decision aids
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Phase II Trial of S-1 as Maintenance Treatment After Gemcitabine Plus Cisplatin Regimen Chemotherapy in Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma.
Status: UNKNOWN
Conditions: Nasopharyngeal Carcinoma
Interventions: DRUG: S-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Flavopiridol in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Cancer|Thromboembolism
Interventions: DRUG: acetylsalicylic acid|DRUG: alvocidib|DRUG: clopidogrel bisulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Neurophysiologic Biomarkers in Rett Syndrome
Status: RECRUITING
Conditions: Rett Syndrome|RTT|Rett Syndrome, Atypical
Interventions: OTHER: EEG and Auditory and Visual Evoked Potentials (AEP and VEP)|OTHER: Clinical assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Randomized Trial of Enteral Vitamin D Supplementation in Infants < 28 Weeks Gestational Age or <1000 Grams Birth Weight
Status: RECRUITING
Conditions: Vitamin D Deficiency
Interventions: DIETARY_SUPPLEMENT: Placebo|DIETARY_SUPPLEMENT: 800 IU/day vitamin D supplementation with feedings in the first 28 days after birth|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Efficacy and Safety of Tanfanercept (HL036) in Dry Eye Disease
Status: SUSPENDED
Conditions: Dry Eye
Interventions: DRUG: tanfanercept|DRUG: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Immediate Effect of Defocus Spectacles On the Choroid Thickness Using Optical Coherence Tomography on Children
Status: COMPLETED
Conditions: Myopia
Interventions: DEVICE: Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: PIR of Quadratus Lumborum With and Without Gluteus Maximus Activation in Innominate Upslip Suprapubic Dysfunction
Status: UNKNOWN
Conditions: Innominate Upslip Suprapubic Dysfunction
Interventions: OTHER: Post isometric relaxation of quadratus lumborum and gluteus Gluteus maximus activation exercises|OTHER: post isometric relaxation of the Quadratus lumborum
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Birth Control Patch Study
Status: COMPLETED
Conditions: Contraception
Interventions: DRUG: Ethinylestradiol/Gestodene (FC Patch Low BAY86-5016)|DRUG: Norelgestromin/Ethinylestradiol (EVRA)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effectiveness of a Telerehabilitation Program Based on Specific Neck Exercises in Patients With Forward Head Posture.
Status: RECRUITING
Conditions: Forward Head Posture|Neck Pain|Telerrehabilitation|Deep Cervical Muscles|Specific Neck Exercises|Neck Muscles|Exercise Therapy
Interventions: OTHER: Spinertial Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Randomized Phase II Efficacy, Activity and Safety Study of GLQ223 Alone and in Combination With Zidovudine in Symptomatic HIV-Infected Patients Without Prior Treatment With GLQ223 or Trichosanthin
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Trichosanthin|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Ibuprofen Gel or Capsaicin Cream for my Painful Knee Osteoarthritis?
Status: COMPLETED
Conditions: Osteoarthritis, Knee
Interventions: DRUG: Topical NSAID|DRUG: Topical Capsaicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Clinical Effects and Safety of 3% Diquafosol After Cataract Surgery
Status: COMPLETED
Conditions: Dry Eye Syndromes
Interventions: DRUG: Diquafosol (Diquas)|DRUG: Sodium Hyaluronate (Hyalein)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Orvepitant for Chronic Cough in Patients With Idiopathic Pulmonary Fibrosis
Status: COMPLETED
Conditions: Cough|Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Orvepitant Maleate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial to Investigate Efficacy and Usability of Published Best Practice to Control Glycaemia
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: Insulin Aspart, Insulin Glargine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer
Status: RECRUITING
Conditions: Rectal Cancer
Interventions: DRUG: irinotecan liposomes+capecitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Healthy Term Infants Fed Milk-Based Formulas
Status: COMPLETED
Conditions: Healthy Term Infant
Interventions: OTHER: Experimental powdered milk-based infant formula with an alternate fat blend|OTHER: A powdered milk-based infant formula, standard fat blend
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sequential Conditioning in Haploidentical Transplantation for Hematopoietic Stem Cells in Patients With Relapsed or Refractory Lymphoid Hematological Disorders
Status: COMPLETED
Conditions: Refractory or Relapsed Lymphoid Haemopathy
Interventions: DRUG: Sequential Packaging (SET)|DRUG: Transfusion graft|DRUG: Prevention of GVHD|DRUG: Care supports|DRUG: Lymphocyte injection of prophylactic donor (PDLI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Transdermal Lidocaine for Pain Control During Hysterosalpingography
Status: UNKNOWN
Conditions: Infertility, Female
Interventions: DRUG: lidocaine patch|DRUG: Sham patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Silodosin in the Treatment of Natural Expulsion in Patients With Ureteral Stones
Status: COMPLETED
Conditions: Ureteral Stone
Interventions: DRUG: Silodosin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Using the Cholinergic Anti-Inflammatory Pathway to Treat Systemic Lupus Musculoskeletal Pain
Status: UNKNOWN
Conditions: Lupus Erythematosus, Systemic|Musculoskeletal Pain
Interventions: DEVICE: Vagus nerve stimulation|DEVICE: Sham vagus nerve stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Evaluation of Internal Fit of Milled BioHPP Polyetheretherketone (PEEK) - Based Versus Zirconia-Based Single Crowns
Status: UNKNOWN
Conditions: Badly Decayed Teeth andTeeth Restored With Large Filling Restorations and Endodontically Treated Teeth and Malformed Teeth and Malposed Teeth
Interventions: OTHER: BioHPP PEEK copings veneered with composite resin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dose-finding Study for AdimrSC-2f Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: AdimrSC-2f
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacodynamics of Entospletinib in Adults With Relapsed or Refractory Hematologic Malignancies
Status: TERMINATED
Conditions: Chronic Lymphocytic Leukemia|Mantle Cell Lymphoma|Diffuse Large B-cell Lymphoma|Non-FL Indolent Non-Hodgkin's Lymphoma|Follicular Lymphoma
Interventions: DRUG: Entospletinib MM|DRUG: Entospletinib SDD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage
Status: COMPLETED
Conditions: Trypanosomiasis, African|Sleeping Sickness|Trypanosomiasis; Gambian
Interventions: DRUG: Fexinidazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65)
Status: ACTIVE_NOT_RECRUITING
Conditions: Ovarian Cancer|Carcinoma, Ovarian Epithelial|Fallopian Tube Neoplasms
Interventions: BIOLOGICAL: Pembrolizumab|DRUG: Paclitaxel|DRUG: Bevacizumab|OTHER: Placebo for pembrolizumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compliance: Role Emerges for Success in Chronic Myelogenous Leukaemia (CML): Evaluation aND Optimisation
Status: COMPLETED
Conditions: Chronic Myelogenous Leukemia (CML)
Interventions: OTHER: compliance supporting measures
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Volumetric Analysis of Hepatocellular Carcinoma After Transarterial Chemoembolization
Status: COMPLETED
Conditions: Hepatocellular Carcinoma|Hepatocellular Carcinoma by BCLC Stage
Interventions: PROCEDURE: Transarterial Chemoembolization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Quality Control of CE-Certified Phonak Hearing Aids - 2019_19
Status: COMPLETED
Conditions: Hearing Loss|Sensorineural Hearing Loss
Interventions: DEVICE: Phonak Bolero M90-M|DEVICE: Roger Select
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of HB-1 for Panic Disorder
Status: NOT_YET_RECRUITING
Conditions: Panic Disorder|Mental Illness
Interventions: DRUG: HB-1|DRUG: Telmisartan Only Product in Oral Dose Form|DRUG: Verapamil Only Product in Oral Dose Form|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Target Oxygen Ranges in Infants With Pulmonary Hypertension
Status: NOT_YET_RECRUITING
Conditions: Bronchopulmonary Dysplasia|Pulmonary Hypertension
Interventions: DEVICE: higher oxygen saturation target using Nellcor pulse oximetry sensors|DEVICE: lower oxygen saturation target using Nellcor pulse oximetry sensors
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 2L NRL994 With NaP Preparation in Colon Cleansing Prior to Colonoscopies for Colon Tumor Screening
Status: COMPLETED
Conditions: Colonoscopy
Interventions: DRUG: Macrogol 3350 Na sulphate NaCl KCl Ascorbic Acid Na Ascorbate|DRUG: Sodium Phosphate solution (NaP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Acute Stress Recovery
Status: UNKNOWN
Conditions: Stress
Interventions: BEHAVIORAL: MindBreaks - Audio-visual|BEHAVIORAL: MindBreaks - Auditory-only|BEHAVIORAL: MindBreaks - Visual-only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Low Risk Non ST Elevation Myocardial Infarction With or Without Intensive Care Unit Admission
Status: RECRUITING
Conditions: Non-ST Elevated Myocardial Infarction
Interventions: OTHER: Hospitalized in Intensive care unit|OTHER: Hospitalized in General cardiology ward
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of the Efficacy and Safety of Hyaluronic Acid Injection in Labia Majora for Volume Restoration
Status: COMPLETED
Conditions: Vulvar Atrophy
Interventions: DEVICE: DESIRIAL® PLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing of High Flow Nasal Cannula Versus Cpap for Initial Respiratory Stabilisation of Very Premature Infants
Status: NOT_YET_RECRUITING
Conditions: Premature; Infant
Interventions: DEVICE: High-flow-nasal-cannula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of EN3835 in the Treatment of EFP in Women
Status: COMPLETED
Conditions: Edematous Fibrosclerotic Panniculopathy|Cellulite
Interventions: BIOLOGICAL: Collagenase Clostridium Histolyticum
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of Adaptive 18F-FDG-PET Biological Intensity-modulated Radiotherapy (BG-IMRT) in Patients With Head and Neck Tumor
Status: COMPLETED
Conditions: Head and Neck Tumor
Interventions: PROCEDURE: 18F-FDG-PET radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEssary Plus Physiotherapy for Pelvic Organ Prolapse (PEPPY)
Status: COMPLETED
Conditions: Pelvic Organ Prolapse
Interventions: OTHER: PFMT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High-fiber Diet on the Body and the Brain
Status: COMPLETED
Conditions: Diet Modification|Overweight
Interventions: DIETARY_SUPPLEMENT: inulin|DIETARY_SUPPLEMENT: maltodextrin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Neuroprotective Effects of RPC on the Neurosurgery
Status: COMPLETED
Conditions: s100b
Interventions: PROCEDURE: remote preconditioning
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Computerized Cognitive Remediation for Geriatric Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder|Major Depressive Episode
Interventions: OTHER: computerized cognitive remediation|OTHER: computerized cognitive remediation:Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 2a Open-Label Study to Evaluate the Efficacy and Safety of MORF-057 in Adults With UC
Status: ACTIVE_NOT_RECRUITING
Conditions: Inflammatory Bowel Diseases|Colitis, Ulcerative
Interventions: DRUG: MORF-057
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of MK-8353 + Selumetinib in Advanced/Metastatic Solid Tumors (MK-8353-014)
Status: COMPLETED
Conditions: Solid Tumors
Interventions: DRUG: MK-8353|DRUG: Selumetinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Clozapine-Induced Hypersalivation Ipratropium Bromide
Status: COMPLETED
Conditions: Hypersalivation
Interventions: DRUG: ipratropium bromide 0.03% spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of LY3323795 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3323795|DRUG: Itraconazole|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Carcinoembryonic Antigen-loaded Dendritic Cells in Advanced Colorectal Cancer Patients
Status: COMPLETED
Conditions: Colorectal Cancer|Liver Metastases
Interventions: BIOLOGICAL: CEA-loaded dendritic cell vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pharmacokinetic Study of Pediatric Micafungin Prophylaxis
Status: TERMINATED
Conditions: Immunocompromised|Bone Marrow Transplant|Cancer
Interventions: DRUG: Micafungin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison Levobupivacaine and Ropivacaine for TAP-block After Caesarean Section
Status: UNKNOWN
Conditions: Pain, Postoperative
Interventions: DRUG: Levobupivacaine Solution|DRUG: Ropivacaine Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: REduCing Immunogenicity to PegloticasE (RECIPE) Study
Status: COMPLETED
Conditions: Gout Chronic
Interventions: DRUG: Pegloticase 8 MG/ML [Krystexxa]|DRUG: MMF|DRUG: Placebo|DRUG: Pegloticase 8 MG/ML [Krystexxa]
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer
Status: COMPLETED
Conditions: Head and Neck Neoplasms
Interventions: DRUG: Pemetrexed|DRUG: Cetuximab|DRUG: Cisplatin|DIETARY_SUPPLEMENT: Folic Acid|DIETARY_SUPPLEMENT: Vitamin B12
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Primary Peritoneal Cavity Cancer
Interventions: DRUG: docetaxel|DRUG: vandetanib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of S-1 in Combination With Sorafenib for Patients With Advanced Hepatocellular Carcinoma
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: sorafenib, TS-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Validity of Customized Orthodontic Bracket Set up
Status: COMPLETED
Conditions: Orthodontic Appliance Complication
Interventions: DEVICE: Insignia™ twin brackets|DEVICE: Maestro® 3D Ortho Studio software (Discovery, Dentaurum®, Ispringen, Germany)|DEVICE: Ray set® device (Discovery, Dentaurum®, Ispringen, Germany)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Genetic Testing or Clinical Assessment in Determining the Need for Chemotherapy in Women With Breast Cancer That Involves No More Than 3 Lymph Nodes
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: anthracycline-based|DRUG: docetaxel and capecitabine|DRUG: tamoxifen|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Randomized, Double-blind, Placebo-controlled, and Multi-center Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia
Status: RECRUITING
Conditions: Immune Thrombocytopenia|Treatment
Interventions: DRUG: CM313 Injection|DRUG: Placebo Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Influence of Clopidogrel on the Pharmacodynamics and Safety of Fradafiban in Healthy Male Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Lefradafiban|DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health
Status: UNKNOWN
Conditions: Cholesterol|Hyperlipidemia|Hypercholesteremia
Interventions: DIETARY_SUPPLEMENT: Ad-Chol-Pre|DIETARY_SUPPLEMENT: Half-dose Ad-Chol-Pre|OTHER: Defatted egg yolk without the active ingredient of the other two interventions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose:
Clinical trial: Bicalutamide Therapy in Young Women With NAFLD and PCOS
Status: RECRUITING
Conditions: NAFLD|PCOS
Interventions: DRUG: Bicalutamide 50 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Qigong For PPSP In Breast Cancer Pain In Breast Cancer Survivors
Status: COMPLETED
Conditions: Breast Cancer Surgery Pain|Breast Cancer|Stage 0-III Breast Cancer
Interventions: OTHER: Qigong Mind-Body Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of TENS and IES on the Autonomous Balance of Normotens Volunteers and Hypertensive Patients
Status: COMPLETED
Conditions: Healthy Volunteers|Hypertension, Essential
Interventions: DEVICE: Transcutaneous nervous electric stimulation (TENS)|DEVICE: Interferential electrical stimulation (IES)|DEVICE: TENS and IES Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Pertuzumab in Combination With Herceptin and Chemotherapy in Participants With HER2-Positive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: DRUG: Pertuzumab|DRUG: Trastuzumab|DRUG: FEC|DRUG: Docetaxel|DRUG: TCH
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions
Status: RECRUITING
Conditions: Heart Defects, Congenital|Pulmonary Arterial Hypertension|Genetic Testing
Interventions: OTHER: Genetic testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Preoperative Immunonutrition in Patients Undergoing Spine Surgery
Status: RECRUITING
Conditions: Arthrosis; Spine
Interventions: DIETARY_SUPPLEMENT: Immuno-nutrition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE