pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Botensilimab, Balstilimab and Regorafenib or Botensilimab and Balstilimab for the Treatment of Advanced or Metastatic Microsatellite Stable Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Colon Adenocarcinoma|Advanced Colorectal Adenocarcinoma|Advanced Rectal Adenocarcinoma|Metastatic Colon Adenocarcinoma|Metastatic Colorectal Adenocarcinoma|Metastatic Rectal Adenocarcinoma|Stage III Colon Cancer AJCC v8|Stage III Colorectal Cancer AJCC v8|Stage III Rectal Cancer AJCC v8|Stage IV Colon Cancer AJCC v8|Stage IV Colorectal Cancer AJCC v8|Stage IV Rectal Cancer AJCC v8
Interventions: BIOLOGICAL: Balstilimab|PROCEDURE: Biopsy|PROCEDURE: Biospecimen Collection|BIOLOGICAL: Botensilimab|PROCEDURE: Computed Tomography|PROCEDURE: Magnetic Resonance Imaging|DRUG: Regorafenib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer-aided Indirect Bonding Versus Traditional Direct Bonding of Brackets in Orthodontic Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Orthodontic Appliances, Fixed
Interventions: PROCEDURE: Direct bonding of Orthodontic brackets|PROCEDURE: Indirect bonding of Orthodontic brackets
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Drug Interaction Study With Fluticasone Furoate/GW642444 Inhalation Powder and Ketoconazole
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FF / GW642444|DRUG: ketoconazole|DRUG: ketoconazole (placebo to match)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: A Study to Evaluate the Dose Response Based on the Efficacy, Safety and Tolerability of Bimekizumab in Subjects With Active Psoriatic Arthritis Which is a Type of Inflammatory Arthritis
Status: COMPLETED
Conditions: Psoriatic Arthritis
Interventions: OTHER: Placebo|DRUG: Bimekizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the HSP90 Inhibitor, STA-9090 in Subjects With Stage IIIB or IV Non-Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: STA 9090
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia
Status: COMPLETED
Conditions: Acute Myeloid Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Untreated Adult Acute Myeloid Leukemia
Interventions: DRUG: daunorubicin hydrochloride|DRUG: cytarabine|DRUG: bortezomib
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Muscle Contraction in the Rehabilitation and Prevention of Degenerative Pain in the Locomotor System
Status: NOT_YET_RECRUITING
Conditions: Pain, Back|Pain, Neck|Pain, Hip Burning|Pain, Shoulder|Arthropathy of Knee|Arthropathy of Hip|Pain Syndrome
Interventions: BEHAVIORAL: Standard advice and Preliminary muscle contraction|BEHAVIORAL: Standard advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pathobiology of Remission of Type 2 Diabetes
Status: UNKNOWN
Conditions: Newly Diagnosed Type 2 Diabetes|Obese
Interventions: OTHER: High Protein (HP) weight loss diet|OTHER: High carbohydrate (HC) weight loss diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Surgical Trial Comparing LIGASURE Assisted Recto-Sigmoid Resection and Omentectomy Compared to Stand
Status: COMPLETED
Conditions: Epithelial Ovarian Cancer
Interventions: OTHER: Standard Surgical resection|DEVICE: LIGASURE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Soft Tissue
Interventions: DRUG: Olaratumab|DRUG: Doxorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study of the Effectiveness and Safety of Mometasone Furoate Nasal Spray (MFNS, SCH 032088) for the Treatment of Nasal Polyps (P05604)
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Mometasone Furoate Nasal Spray (MFNS)|DRUG: Placebo for MFNS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Screening for Prostate Cancer Among Those Prostate-specific Antigen Value Between 2.5 and 4.0 ng/mL
Status: UNKNOWN
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: mpMRI scanning
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS
Status: COMPLETED
Conditions: Myalgic Encephalomyelitis|Chronic Fatigue Syndrome
Interventions: OTHER: Two-day cardiopulmonary exercise test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Telemedicine System and Intelligent Monitoring System Construction of Pediatric Asthma Based on the Electronic Stethoscope
Status: RECRUITING
Conditions: Asthma
Interventions: DEVICE: Electronic Stethoscope|OTHER: Standard treatment according to GINA(2019)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Safety, Tolerability and Activity Study of Multiple Doses of ISIS-SGLT2Rx in Healthy Volunteers
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: ISIS 388626
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gingivitis Treated With Chlorhexidine 0.12% Mouthwash in Young Adults
Status: COMPLETED
Conditions: Age Problem
Interventions: PROCEDURE: 0.12% chlorhexidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Remote Magnetic Navigation-guided Ablation Versus Cryoablation for Persistent Atrial Fibrillation (RECREATION Study)
Status: UNKNOWN
Conditions: Persistent Atrial Fibrillation
Interventions: PROCEDURE: Remote magnetic navigation|PROCEDURE: Cryoablation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Low-Molecular-Weight Heparin (Bemiparin) in the Treatment of Chronic Foot Ulcers in Diabetic Patients
Status: TERMINATED
Conditions: Foot Ulcer, Diabetic|Diabetic Angiopathies
Interventions: DRUG: bemiparin (low molecular weight heparin)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars
Status: UNKNOWN
Conditions: Acne Scars
Interventions: PROCEDURE: Laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Vulnerable Plaque of Carotid Artery With Chinese Herbal and Insects Medicine
Status: UNKNOWN
Conditions: Carotid Artery Plaque
Interventions: DRUG: Herbal Medicine C-117|DRUG: The Placebo of Herbal Medicine C-117
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: DAPHNE Study: Direct Anticoagulant PHarmacogeNEtic
Status: COMPLETED
Conditions: Anticoagulants and Bleeding Disorders
Interventions: DIAGNOSTIC_TEST: CYP3A4/5 and P-gp phenotyping|GENETIC: CYP3A4/5 and P-gp genotyping
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Pilot Study on the Use of Seysara for Rosacea
Status: COMPLETED
Conditions: Acne Rosacea
Interventions: DRUG: sarecycline|DIETARY_SUPPLEMENT: Centrum Adult Multivitamin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety of Engensis in Participants With Amyotrophic Lateral Sclerosis
Status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: BIOLOGICAL: Engensis|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Safety, Tolerability and Pharmacokinetics of ASP015K in Healthy Subjects
Status: COMPLETED
Conditions: Healthy Volunteers|Pharmacokinetics of ASP015K
Interventions: DRUG: ASP015K|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Individual Metabolism and Physiology Signature Study
Status: COMPLETED
Conditions: Insulin Resistance|Metabolic Syndrome X|Obesity
Interventions: OTHER: DGA Diet Plan|OTHER: NHANES Diet Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Nitrous Oxide for Major Depressive Disorder
Status: COMPLETED
Conditions: Depressive Disorder|Major Depressive Disorder|Treatment Resistant Depression|Depressive Disorder, Major|Depression
Interventions: DRUG: Nitrous Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Lithium for the Treatment of Pediatric Mania.
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DRUG: Lithium Carbonate|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Sharp Versus Blunt Fascial Incision at Caesarean Section
Status: COMPLETED
Conditions: Cesarean Section
Interventions: PROCEDURE: Blunt right, sharp left|PROCEDURE: Blunt left, sharp right
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The Effect of Brief Versus Individually Tailored Dietary Advice on Change in Lipids, Blood Pressure, and Diet in Patients With Inflammatory Joint Disease
Status: RECRUITING
Conditions: Rheumatoid Arthritis|Psoriatic Arthritis|Spondyloarthritis
Interventions: OTHER: Individually tailored diet counseling|OTHER: The brief standardized 4-minute heart healthy dietary advice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Role of Left Stellate Ganglion Block in Offering Myocardial Protection in On-pump Mitral Valve Replacement? A Histopathological and Clinical Assessment
Status: NOT_YET_RECRUITING
Conditions: Open Mitral Cardiac Surgery
Interventions: PROCEDURE: sonar guided stellate ganglion injection|PROCEDURE: sonar guided stellate ganglion block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: 6-Session Treatment for Generalized Anxiety Disorder
Status: COMPLETED
Conditions: Generalized Anxiety Disorder
Interventions: BEHAVIORAL: Behavioural experiments for intolerance of uncertainty (BE-IU)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Involving Community Pharmacies in Improving Asthma Outcomes in an Urban Pediatric Population
Status: COMPLETED
Conditions: Asthma
Interventions: BEHAVIORAL: Enhanced Pharmacy Care|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: SVF Combined With Functional Self-assembling Peptide Nanofiber Hydrogels in the Treatment of Spinal Cord Injury
Status: RECRUITING
Conditions: Safety Issues
Interventions: PROCEDURE: Stromal Vascular Fraction (SVF) combined with Functional self-assembling peptide nanofiber hydrogels
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide, Carfilzomib, Thalidomide, and Dexamethasone in Treating Patients With Newly Diagnosed Active Multiple Myeloma
Status: COMPLETED
Conditions: Multiple Myeloma|Stage I Multiple Myeloma|Stage II Multiple Myeloma|Stage III Multiple Myeloma
Interventions: DRUG: carfilzomib|DRUG: cyclophosphamide|DRUG: thalidomide|DRUG: dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Post-ERCP Cholecystectomy. How ERCP and ERCP-related Variables Effect the Outcomes?
Status: COMPLETED
Conditions: Endoscopic Retrograde Cholangiopancreatography|ERCP-Laparoscopic Cholecystectomy Interval|Number of Preoperative ERCPs|Stone Extraction Status in ERCP Procedures|Biliary Stents|Mechanical Lithotripsy
Interventions: PROCEDURE: Endoscopic Retrograde Cholangiopancreatography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lymphatic Mapping, Sentinel Lymph Node Analysis, and Blood Tests in Detecting and Predicting Early Micrometastases in Patients With Colorectal Cancer
Status: UNKNOWN
Conditions: Colorectal Cancer
Interventions: DRUG: isosulfan blue|GENETIC: polymerase chain reaction|OTHER: diagnostic laboratory biomarker analysis|OTHER: immunohistochemistry staining method|PROCEDURE: diagnostic lymphadenectomy|PROCEDURE: therapeutic conventional surgery|PROCEDURE: therapeutic lymphadenectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluation of Vildagliptin (Galvus®) as add-on to Insulin in New-onset Type 1 Diabetes Mellitus
Status: UNKNOWN
Conditions: Type 1 Diabetes|Insulin Dependent Diabetes|Juvenile Onset Diabetes Mellitus|Autoimmune Diabetes
Interventions: DRUG: Vildagliptin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Abuse Liability of Very Low Nicotine (VLN) Mentholated Cigarettes
Status: COMPLETED
Conditions: Tobacco Use
Interventions: OTHER: VLN menthol cigarettes (A)|OTHER: Usual Brand Menthol Cigarettes (B)|DRUG: Nicotine gum (C)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Cord Blood Serum in the Treatment of Neuro-Degenerative Ophthalmic Diseases. 1-Glaucoma
Status: COMPLETED
Conditions: Glaucoma|Neuro-Degenerative Disease
Interventions: OTHER: CBS eyedrop
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a High Protein Diet on the 24-hour Profile of Ghrelin, GH (Growth Hormone) and IGF-1 (Insulin-like Growth Factor-1)
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: OTHER: LoBag Diet - test phase|OTHER: LoBAG Diet - control phase
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Antioxidant and Anti-inflammatory Effect of Matcha Tea Intake on Periodontal Health
Status: ACTIVE_NOT_RECRUITING
Conditions: Gingival Disease
Interventions: DIETARY_SUPPLEMENT: green tea|DIETARY_SUPPLEMENT: matcha tea
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Assess the Pharmacokinetics and Safety of Single Doses of Anifrolumab in Healthy Subjects
Status: COMPLETED
Conditions: Safety|Pharmacokinetics|Healthy Subjects
Interventions: DRUG: Anifrolumab SC injection (300mg)|DRUG: Anifrolumab IV infusion (300mg)|DRUG: Anifrolumab SC infusion (600mg)|DRUG: Anifrolumab placebo SC injection (300mg)|DRUG: Anifrolumab placebo IV infusion (300mg)|DRUG: Anifrolumab placebo SC infusion (600mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: The Respiratory Protection Effectiveness Clinical Trial
Status: COMPLETED
Conditions: Influenza|Respiratory Syncytial Viruses|Paramyxoviridae Infections|Coronavirus|Rhinovirus
Interventions: DEVICE: N95 Respirator|DEVICE: Medical/surgical mask
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Once - Daily Oral Direct Factor Xa Inhibitor Rivaroxaban In The Long-Term Prevention Of Recurrent Symptomatic Venous Thromboembolism In Patients With Symptomatic Deep-Vein Thrombosis Or Pulmonary Embolism. The Einstein-Extension Study
Status: COMPLETED
Conditions: Venous Thromboembolism
Interventions: DRUG: Rivaroxaban (Xarelto, BAY59-7939)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study to Evaluate and Compare Injections of Autologous Dermal and Epidermal Cells Into the Balding Scalp of Subjects With Hair Loss (CA-0004512)
Status: COMPLETED
Conditions: Androgenetic Alopecia|Male Pattern Baldness|Female Pattern Baldness
Interventions: BIOLOGICAL: Autologous cultured dermal and epidermal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Peripheral Intravenous Catheterization in the Pediatric Intensive Care Unit.
Status: UNKNOWN
Conditions: Peripheral Venous Cannulation
Interventions: PROCEDURE: US guided dynamic needle tip positioning peripheral intravenous cannulation|PROCEDURE: Traditional peripheral intravenous cannulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of the Quality of Life and Treatment Response to Once Weekly Epoetin Beta (Recormon) Treatment in Anemic Participants With Solid and Lymphoid Malignancies
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin beta
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Long-term Safety and Efficacy of Fenebrutinib in Participants Previously Enrolled in a Fenebrutinib Chronic Spontaneous Urticaria (CSU) Study
Status: TERMINATED
Conditions: Urticaria
Interventions: DRUG: GDC-0853
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma
Status: RECRUITING
Conditions: Urothelial Carcinoma
Interventions: DRUG: BL-B01D1|DRUG: PD-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia
Status: COMPLETED
Conditions: Fibromyalgia
Interventions: DRUG: Low dose Hydrocortisone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma
Status: COMPLETED
Conditions: Nasopharyngeal Carcinoma
Interventions: OTHER: Drug: Taxol,cisplatin and capecitabine|OTHER: Drug: Cisplatin and 5-Fluorouracil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Personalized CAPTEM Radiopeptide Therapy of Advanced, Non-resectable Neuroendocrine Cancer
Status: UNKNOWN
Conditions: Neuroendocrine Tumors
Interventions: DRUG: 177Lu-DOTATOC
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computed Tomography Coronary Angiography Before Stent Implantation
Status: COMPLETED
Conditions: Stable Coronary Artery Disease
Interventions: OTHER: PCI on the basis of coronary angiography|PROCEDURE: CT guided PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Lamotrigine Bioequivalence
Status: COMPLETED
Conditions: Epilepsy
Interventions: DRUG: Brand lamotrigine|DRUG: Generic lamotrigine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Diagnosis of Mycoplasma Pneumoniae Infection With Detection of Specific Antibody-secreting Cells in Community-acquired Pneumonia (CAP) Patients of the Randomised Placebo-controlled Multi-centre Effectiveness Trial of Adjunct Betamethasone Therapy
Status: UNKNOWN
Conditions: Community-acquired Pneumonia
Interventions: DIAGNOSTIC_TEST: Specific antibody-secreting cell (ASC) enzyme-linked immunspot (ELISpot) assay
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Trial to Compare the Efficacy, Safety and Tolerability of Combinations of 3 Anti-malarial Drugs Against Combina-tions of 2 Anti-malarial Drugs.
Status: RECRUITING
Conditions: Plasmodium Falciparum Malaria (Uncomplicated)
Interventions: DRUG: Artemether-lumefantrine+ Amodiaquine (AL+AQ)|DRUG: Artemether-lumefantrine + placebo (AL+PBO)|DRUG: Artesunate-mefloquine+piperaquine (AS-MQ+PPQ)|DRUG: Artesunate-mefloquine+placebo (AS-MQ+PBO)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Impact of Orsiro™ Stent in Patient With Chronic Kidney Disease
Status: ACTIVE_NOT_RECRUITING
Conditions: Chronic Kidney Diseases|Coronary Artery Disease
Interventions: PROCEDURE: Percutaneous coronary intervention|DEVICE: Orsiro™ or Orsiro_Mission™ stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Efficacy of Ramelteon in Adults With Chronic Insomnia
Status: COMPLETED
Conditions: Chronic Insomnia
Interventions: DRUG: Ramelteon|DRUG: Ramelteon|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pilot Project on Interdisciplinary Therapy of Obesity
Status: RECRUITING
Conditions: Obesity|Weight Loss
Interventions: PROCEDURE: Laparoscopic gastric sleeve|PROCEDURE: Gastric Banding|PROCEDURE: Multidisciplinary lifstyle intervention|PROCEDURE: Roux-en-Y Bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Asymptomatic Versus Symptomatic Mild COPD: Comparisons at Rest and at Exercise
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Cardio-pulmonary exercise testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Immunogenicity and Safety of an Inactivated COVID-19 Vaccine
Status: COMPLETED
Conditions: COVID-19
Interventions: BIOLOGICAL: Inactivated COVID-19 Vaccine|BIOLOGICAL: 23-valent pneumococcal polysaccharide vaccine|BIOLOGICAL: Inactivated Hepatitis A Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS
Status: UNKNOWN
Conditions: Acute Respiratory Distress Syndrome
Interventions: PROCEDURE: End-expiratory lung volume measurement and incremental PEEP titration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Assess the Safety, Tolerability, and Pharmacokinetics of AZD6234 Following Single Ascending Dose Administration to Healthy Subjects Who Are Overweight or Obese
Status: COMPLETED
Conditions: Healthy Participants
Interventions: DRUG: AZD6234|DRUG: Placebo|COMBINATION_PRODUCT: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Outcomes of Two Existing Routine Clinical Therapies for Dental Prophylaxis
Status: COMPLETED
Conditions: Gingivitis
Interventions: PROCEDURE: Plaque disclosed with air flow|PROCEDURE: Plaque disclosed with rubber cup|PROCEDURE: Non plaque disclosed air flow|PROCEDURE: Non plaque disclosed rubber cup
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease
Status: UNKNOWN
Conditions: Stevens-Johnson Syndrome|Graft Versus Host Disease in Eye|Sjogren's Syndrome|Dry Eye
Interventions: DEVICE: Tangible Boost|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mesenchymal Stem Cells as a Treatment for Oral Complications of Graft-versus-host Disease
Status: WITHDRAWN
Conditions: Graft -Versus-host-disease
Interventions: BIOLOGICAL: Mesenchymal stromal cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary Obstruction
Status: UNKNOWN
Conditions: Bile Duct Obstruction, Extrahepatic|Cancer of the Pancreas|Cancer of the Bile Duct|Biliary Stricture
Interventions: DEVICE: Biliary stent
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Two-Part Single and Multiple Ascending Dose Trial of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LBT-3627 in Healthy Participants and in Participants With Parkinson's Disease.
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: LBT-3627|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of BAY59-8862 in Taxane-Resistant Metastatic Breast Cancer Patients
Status: COMPLETED
Conditions: Breast Neoplasms|Breast Cancer, Metastatic
Interventions: DRUG: BAY59-8862 (Cytotoxic Taxane)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 3D-printed Crowns Versus Prefabricated Stainless-Steel Crowns for Intermediate Restoration of Compromised First Permanent Molars
Status: RECRUITING
Conditions: 3D Printed Crowns
Interventions: PROCEDURE: 3D printed crown|PROCEDURE: stanless steel crown
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Tyrosine Supplementation on Cognitive Performance and Mood During Military Stress
Status: COMPLETED
Conditions: Reaction to Severe Stress, Unspecified
Interventions: OTHER: Tyrosine-Containing Food Bar|OTHER: Placebo Bar
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Hyaluronic Acid Hydro-dissection Use in Idiopathic Carpal Tunnel Syndrome Guided by Ultrasonic Study
Status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Interventions: DRUG: Sodium Hyaluronate|DEVICE: ultrasound|DRUG: Sodium Hyaluronate and 1% lidocain|DRUG: Corticosteroid and 1%lidocain
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: 20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 3-Dose Series in Healthy Infants
Status: COMPLETED
Conditions: Pneumococcal Disease
Interventions: BIOLOGICAL: 20-valent pneumococcal conjugate vaccine|BIOLOGICAL: 13-valent pneumococcal conjugate vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: DRUG: Urea Cream 20%|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Flexible Tip Bougie vs Tube With Stylet for Intubation With Videolaryngoscopy.
Status: RECRUITING
Conditions: Intubation; Difficult or Failed
Interventions: DEVICE: Endotracheal Tube with Stylet|DEVICE: Flexible Tip Bougie
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Avoiding Neuromuscular Blockers to Reduce Complications
Status: TERMINATED
Conditions: Respiratory Failure|Respiratory Infection|Aspiration Pneumonia|Pneumonitis|Atelectasis|Bronchospasm
Interventions: DRUG: Neuromuscular Blocking Agents|DRUG: Anesthetic Adjuncts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Ear Acupuncture in Preventing Chemotherapy Induced Nausea and Vomiting in Cancer Patients
Status: COMPLETED
Conditions: Pediatric Cancer|Chemotherapy-induced Nausea and Vomiting|Chemotherapy Effect
Interventions: DEVICE: Press needle acupuncture|DEVICE: Plesterin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Clindamycin to Reduce Preterm Birth in a Low Resource Setting
Status: COMPLETED
Conditions: Pregnancy|Prematurity|Preterm Birth|Bacterial Vaginosis
Interventions: DRUG: Clindamycin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Iron Bioavailability From Encapsulated Ferrous Sulphate
Status: COMPLETED
Conditions: Iron Deficiency
Interventions: DIETARY_SUPPLEMENT: non-encapsulated FeSO4|DIETARY_SUPPLEMENT: encapsulated FeSO4, before cooking|DIETARY_SUPPLEMENT: encapsulated FeSO4, after cooking|DIETARY_SUPPLEMENT: non-encapsulated FeSO4 + ascorbic acid|DIETARY_SUPPLEMENT: encapsulated FeSO4 + ascorbic acid, before cooking|DIETARY_SUPPLEMENT: encapsulated FeSO4 + ascorbic acid, after cooking
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Ibrutinib and Nivolumab in Treating Participants With Metastatic Solid Tumors
Status: COMPLETED
Conditions: Metastatic Malignant Solid Neoplasm
Interventions: DRUG: Ibrutinib|OTHER: Laboratory Biomarker Analysis|BIOLOGICAL: Nivolumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Platelet Rich Fibrin Matrix as Regenerative Material in Intraosseous Defects
Status: COMPLETED
Conditions: Regenerative Inflammation
Interventions: BIOLOGICAL: Platelet Rich Fibrin Matrix kit|PROCEDURE: surgical open flap debridement
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of the Effect of Ketoconazole on the PK of Multiple Doses of Cediranib in Patients With Solid Tumours
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: cediranib (RECENTIN TM, AZD2171)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: An Asian Study to Assess the Properties and Profile of Ticagrelor in Patients With Stable Coronary Artery Disease
Status: COMPLETED
Conditions: Stable Coronary Artery Disease
Interventions: DRUG: ticagrelor|DRUG: clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effects the Glycemic Index on Metabolic Risk Markers
Status: COMPLETED
Conditions: Metabolic Syndrome X
Interventions: DIETARY_SUPPLEMENT: Low GI+high GI|DIETARY_SUPPLEMENT: High GI+low GI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Phase4/Symbicort® Versus Pulmicort Flexhaler® in African Americans
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide / formoterol fumarate (SYMBICORT)|DRUG: Budesonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Biscuit Containing Kothala Himbutu on Blood Glucose in Patients With Diabetes. A Randomized Control Study
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Kothala Himbutu Biscuit|DIETARY_SUPPLEMENT: Placebo Biscuit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of an ICU Diary on the Well-being of Patients and Families. A Prospective Multicenter Mixed Study
Status: COMPLETED
Conditions: Stress Disorders Post Traumatic
Interventions: OTHER: ICU diary
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Exercise Oscillatory Breathing and Sildenafil in Heart Failure
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Sildenafil|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men
Status: COMPLETED
Conditions: Obesity|Gender|Problem of Aging
Interventions: PROCEDURE: Cardiopulmonary Exercise Stress Test|PROCEDURE: Climatic-Controlled Cardiopulmonary Exercise Stress Test|PROCEDURE: Body Composition Evaluation|PROCEDURE: Pre-Exercise Risk Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Lateral Window Versus Intralift™ Sinus Floor Elevation
Status: COMPLETED
Conditions: Intraoperative Outcomes|Postoperative Outcomes
Interventions: PROCEDURE: Sinus floor elevation|DEVICE: Sinus floor elevation using an ultrasonic device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Deferiprone for the Prevention of Contrast-Induced Acute Kidney Injury
Status: COMPLETED
Conditions: Contrast-Induced Acute Kidney Injury
Interventions: DRUG: CRMD-001-Deferiprone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Belinostat and Bortezomib in Treating Patients With Relapsed or Refractory Acute Leukemia or Myelodysplastic Syndrome
Status: COMPLETED
Conditions: Acute Lymphocytic Leukemia|Acute Myeloid Leukemia|Myelodysplastic Syndrome|Chronic Myelogenous Leukemia
Interventions: DRUG: bortezomib|DRUG: belinostat|OTHER: laboratory biomarker analysis|GENETIC: western blotting|OTHER: pharmacological study|OTHER: flow cytometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC
Status: ACTIVE_NOT_RECRUITING
Conditions: Tuberous Sclerosis Complex
Interventions: DRUG: NPC-12Y gel|DRUG: NPC-12Y placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Gulf War Illness Nasal Irrigation Study
Status: COMPLETED
Conditions: Persian Gulf Syndrome|Chronic Sinusitis|Fatigue|Acute Sinusitis
Interventions: OTHER: Nasal Irrigation - Saline|DRUG: Nasal Irrigation - Xylitol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gallium-68 Citrate PET Used in Prostate Cancer
Status: COMPLETED
Conditions: Prostatic Neoplasms
Interventions: DRUG: Gallium-68 citrate|PROCEDURE: Positron Emission Tomography (PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Correlation of Serum Adropin to Testosterone and Adiponectin in Obese Men
Status: COMPLETED
Conditions: Obesity|Dyslipidemias
Interventions: DIAGNOSTIC_TEST: lipid profile: Total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and high density lipoprotein (HDL))|DIAGNOSTIC_TEST: Total testosterone|DIAGNOSTIC_TEST: Adropin|DIAGNOSTIC_TEST: Adiponectin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Pre-exposure Prophylaxis (PrEP) Uptake and Adherence Intervention for Women With Trauma-related Conditions
Status: NOT_YET_RECRUITING
Conditions: Substance Use
Interventions: BEHAVIORAL: Integrated Intervention to Promote PrEP Uptake|OTHER: Standard Treatment Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Multiple Treatments for Ebola Virus Disease (EVD)
Status: UNKNOWN
Conditions: Ebola Virus Disease
Interventions: DRUG: Azithromycin|DRUG: Sunitinib and Erlotinib|DRUG: Atorvastatin and Irbesartan|OTHER: IV fluids and laboratory testing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Theobromine, Vascular Function and Intestinal apoA-I Production
Status: COMPLETED
Conditions: Cardiovascular Disease
Interventions: DIETARY_SUPPLEMENT: Theobromine|DIETARY_SUPPLEMENT: Placebo drink
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: "Evaluation of Postural Control in Children With Increased Femoral Anteversion"
Status: COMPLETED
Conditions: Femoral Anteversion|Gait Disorders in Children|Postural Control|Postural Stability|Balance
Interventions: OTHER: Biodex Balance System|OTHER: Balance Error Scoring System (BESS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Mindfulness for Parents of Children With Autism Spectrum Disorder Autism Spectrum Disorder
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: BEHAVIORAL: Mindfulness-Based Stress Reduction (MSBR)|BEHAVIORAL: Psychoeducational Support Group (PE)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
Status: NOT_YET_RECRUITING
Conditions: Diabetes|Chronic Kidney Diseases|Cancer|Bowel Disease|Cardiovascular Diseases|Mononucleosis|Flu|Heart Diseases|HIV Infections|AIDS and Infections|Bulimia|Chest Infections|Arthritis|Leukaemia|Alcoholic Liver Disease|Allergies|Alzheimer Disease|Appendicitis|Eczema|Bronchitis|Cellulitis|Cirrhosis|Depression|Gout|High Cholesterol|Indigestion|Obesity|Osteoporosis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Furosemide Pharmacodynamics and Pharmacokinetics After Subcutaneous or Oral Administration
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: Furosemide injection solution for subcutaneous administration (80 mg)|DRUG: Oral Furosemide tablets (80 mg)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Halitosis During Active Orthodontic Treatment
Status: UNKNOWN
Conditions: Halitosis
Interventions: DEVICE: Manual Toothbrush|DEVICE: Dental floss|DEVICE: Waterjet|DEVICE: Electric Toothbrush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Inflammatory Effect Comparison Between Fentanyl and Remifentanil in Mastectomy Under General Anesthesia
Status: COMPLETED
Conditions: Breast Disease|Anesthesia|Inflammatory Response
Interventions: DRUG: Remifentanil|DRUG: Fentanyl
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study
Status: COMPLETED
Conditions: Thalassemia Major
Interventions: DRUG: Busulfan|DRUG: Cyclophosphamide|DRUG: Fludarabine|DRUG: Thymoglobulin|DRUG: cyclosporine A|DRUG: Mycophenolate mofetil|DRUG: Tacrolimus|DRUG: Methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase II Trial of Alisertib With Induction Chemotherapy in High-risk AML
Status: COMPLETED
Conditions: Acute Myeloid Leukemia
Interventions: DRUG: Alisertib|DRUG: Cytarabine|DRUG: Idarubicin|DRUG: Daunorubicin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Meloxicam vs Placebo for Mobilization
Status: COMPLETED
Conditions: Non-Hodgkin's Lymphoma|Hodgkin's Lymphoma|Multiple Myeloma|Hematopoietic Stem Cells
Interventions: DRUG: GCSF|DRUG: meloxicam|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Exercises With Electromyographic Biofeedback in Conservative Treatment of Massive Rotator Cuff Tears
Status: COMPLETED
Conditions: Rotator Cuff Tears
Interventions: OTHER: Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Lifestyle Modification for Weight Loss in Schizophrenia
Status: COMPLETED
Conditions: Obesity|Schizophrenia|Schizoaffective Disorder
Interventions: BEHAVIORAL: Nutritional Lifestyle Modification Group|OTHER: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of EDP-305 in Subjects With Mild and Moderate Hepatic Impairment Compared With Normal Healthy Volunteers
Status: COMPLETED
Conditions: NASH
Interventions: DRUG: EDP 305
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Tasso+ Blood Self-Collection for Clinical Diagnostic Assessment of Various Biomarkers
Status: RECRUITING
Conditions: Blood Self-Collection for Clinical Diagnostic Assessments
Interventions: OTHER: Traditional Venipuncture|DEVICE: Tasso+
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Chloroquine to Treat People With Metabolic Syndrome Aim2 (ARCH-MS)
Status: COMPLETED
Conditions: Metabolic Syndrome X|Overweight|Hypertension|Dyslipidemias|Prediabetic State
Interventions: DRUG: Placebo Comparator: First Intervention (3 weeks)|DRUG: Active Comparator: Second Intervention (3 weeks)|DRUG: Active Comparator: Third Intervention (3 weeks)|DRUG: Active Comparator: Fourth Intervention (3 weeks)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT