pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: RadIal Versus Femoral InvEstigation in ST Elevation Acute Coronary Syndrome
Status: UNKNOWN
Conditions: Coronary Artery Disease|Acute Coronary Syndrome|ST Elevation Acute Myocardial Infarction
Interventions: PROCEDURE: Femoral approach|PROCEDURE: Radial approach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease
Status: TERMINATED
Conditions: Coronary Artery Disease|Chronic Kidney Disease|Hypovitaminosis D|Secondary Hyperparathyroidism
Interventions: DRUG: paricalcitol|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Loving-Kindness Meditation for PTSD
Status: COMPLETED
Conditions: Posttraumatic Stress Disorder|Depression
Interventions: BEHAVIORAL: Loving-Kindness Meditation|BEHAVIORAL: Cognitive Processing Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Behind the Wheel (BTW) Smartphone Application
Status: ACTIVE_NOT_RECRUITING
Conditions: High-risk Driving Events
Interventions: BEHAVIORAL: BTW app with reward-based feedback|BEHAVIORAL: BTW app with situational supervised driving practice|BEHAVIORAL: Sham BTW app
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Etomidate and Propofol on Electroencephalography
Status: UNKNOWN
Conditions: General Anesthesia
Interventions: DRUG: etomidate anesthesia|DRUG: propofol anesthesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Carrimycin in Patients With Locally Advanced, Recurrent, or Metastatic HNSCC (Non NPC): A Phase I Trial
Status: COMPLETED
Conditions: Oral Squamous Cell Carcinoma|Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: Carrimycin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Solving Jigsaw Puzzles on Visuospatial Cognition in Older Adults: Jigsaw Puzzles As Cognitive Enrichment
Status: COMPLETED
Conditions: Cognitive Impairment
Interventions: BEHAVIORAL: Jigsaw puzzles|BEHAVIORAL: Cognitive health counseling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Universal Screening for Maternal Depression With the CHICA System
Status: COMPLETED
Conditions: Maternal Depression
Interventions: OTHER: CHICA PSF plus JIT|OTHER: CHICA maternal depression PSF|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: Substance Use Screening to Encourage Behavior Change Among Young People in Primary Care
Status: NOT_YET_RECRUITING
Conditions: Substance Use|Binge Drinking|Cannabis Use|Adolescent Behavior
Interventions: OTHER: Substance use questionnaire|OTHER: Physical activity questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Maximizing the Dietary Pattern of Older Adults: the Effects of Protein Intake on Protein Kinetics
Status: COMPLETED
Conditions: Sarcopenia
Interventions: OTHER: Recommended Dietary Allowance of Protein|OTHER: Habitual protein intake|OTHER: Optimal Protein Intake
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Safety, Efficacy and Pharmacokinetics of XKDCT023 in DLBCL
Status: UNKNOWN
Conditions: Diffuse Large B Cell Lymphoma
Interventions: OTHER: Autologous anti-CD19 CAR-T cell injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Single-dose, Open-label, Parallel-group Study to Assess the Pharmacokinetics of BAF312 in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function
Status: COMPLETED
Conditions: Renal Impairment
Interventions: DRUG: BAF312
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Detoxified J5 Core Glycolipid/ Group B Meningococcal Outer Membrane Protein Vaccine for Gram-negative Bacterial Sepsis Administered With and Without Synthetic CPG Oligodeoxynucleotide 7909 Adjuvant
Status: TERMINATED
Conditions: Bacterial Sepsis
Interventions: BIOLOGICAL: CPG 7909|BIOLOGICAL: J5-OMP Vaccine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Ultrasonographic Evaluation of Abdominal Muscle Thickness Symmetry and Correlation With Pulmonary Function
Status: COMPLETED
Conditions: Muscle Physiology|Adolescent Idiopathic Scoliosis
Interventions: DIAGNOSTIC_TEST: Bilaterally abdominal muscle thickness with ultrasonography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract
Status: COMPLETED
Conditions: High Risk Polyposis Syndrome|Distal Colonic Lesions|Colorectal Polyps
Interventions: DRUG: indocyanine green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Comparison of the Effect of Preoperative and Postoperative Erector Spina Plan Block and Paravertebral Block on Postoperative Pain in Video Assisted Thoracic Surgery (VATS)
Status: NOT_YET_RECRUITING
Conditions: Anesthesia|Nerve Block|Pain, Postoperative|Thoracic Surgery, Video Assisted
Interventions: PROCEDURE: Erector spina plan block (ESP)|PROCEDURE: Paravertebral block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Benefit and Tolerability of a Probiotic Product in Infants With Abdominal Discomfort
Status: TERMINATED
Conditions: Abdominal Discomfort
Interventions: DIETARY_SUPPLEMENT: Probiotics|DIETARY_SUPPLEMENT: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Digital CBT-I for Patients With Chronic Pain and Insomnia
Status: RECRUITING
Conditions: Chronic Pain|Insomnia
Interventions: BEHAVIORAL: Digital CBT-I|BEHAVIORAL: Digital Sleep hygiene education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Compare the Effects of Bifeprunox and Quetiapine on Weight Changes in Stable Schizophrenic Patients
Status: TERMINATED
Conditions: Schizophrenia
Interventions: DRUG: Bifeprunox|DRUG: Quetiapine|DRUG: Bifeprunox
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Systolic Hypertension in the Elderly Program (SHEP)
Status: COMPLETED
Conditions: Cardiovascular Diseases|Cerebrovascular Disorders|Heart Diseases|Hypertension
Interventions: DRUG: chlorthalidone|DRUG: atenolol|DRUG: reserpine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: |Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: A Study of LY3143753 and LY3185643 in Healthy Participants
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: LY3143753 (Part A)|DRUG: LY3185643 (Part B)|DRUG: Placebo (Part A and Part B)|DRUG: rGlucagon (Part B)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Trial Evaluating the Efficacy and Safety of 2 Fixed Doses of Paliperidone Extended-Release (ER) Tablets in the Treatment of Adult Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: Paliperidone ER
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Effect Of Supraglottic Airway Devices On The Tempromandibular Joint Function Following Prolonged General Anesthesia
Status: UNKNOWN
Conditions: Change of Tempromandibular Joint Function With Supra Glottic Airway Devices
Interventions: DEVICE: Supra glottic airway devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction
Status: COMPLETED
Conditions: Dry Eye Syndrome
Interventions: DEVICE: intense pulsed light|DRUG: Tobramycin and Dexamethasone Ophthalmic Ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery
Status: COMPLETED
Conditions: Hypotension|Hemodynamic Instability|Renal Failure|Myocardial Injury|Anesthesia
Interventions: OTHER: HPI based hemodynamic optimization algorithm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial Investigating the Effect of NN1250 in Japanese Subjects With Type 2 Diabetes
Status: TERMINATED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: insulin degludec
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer
Status: COMPLETED
Conditions: Advanced or Inoperable Gastric Cancer
Interventions: DRUG: Pamiparib|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Association Between the tDCS and FDS for Gait Rehabilitation After Stroke
Status: COMPLETED
Conditions: Stroke
Interventions: DEVICE: Foot Drop Stimulatio - Neuro Orthosis|DEVICE: Transcranial direct brain stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The 5th Generation Tele-Robotic-Assisted Percutaneous Coronary Intervention: A First-in-Human Trial
Status: NOT_YET_RECRUITING
Conditions: Coronary Artery Disease|Myocardial Ischemia|Cardiovascular Diseases|Coronary Disease|Arteriosclerosis
Interventions: DEVICE: 5G Tele-Robotic-Assisted PCI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers
Status: ACTIVE_NOT_RECRUITING
Conditions: Stage III Distal Bile Duct Cancer AJCC v8|Stage III Gallbladder Cancer AJCC v8|Stage III Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIA Distal Bile Duct Cancer AJCC v8|Stage IIIA Gallbladder Cancer AJCC v8|Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8|Stage IIIB Distal Bile Duct Cancer AJCC v8|Stage IIIB Gallbladder Cancer AJCC v8|Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8|Stage IV Distal Bile Duct Cancer AJCC v8|Stage IV Gallbladder Cancer AJCC v8|Stage IV Intrahepatic Cholangiocarcinoma AJCC v8|Stage IVA Gallbladder Cancer AJCC v8|Stage IVB Gallbladder Cancer AJCC v8|Unresectable Extrahepatic Bile Duct Carcinoma|Unresectable Gallbladder Carcinoma|Unresectable Intrahepatic Cholangiocarcinoma
Interventions: DRUG: Cisplatin|DRUG: Gemcitabine Hydrochloride|DRUG: Nab-paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sedation and Analgesia for Transjugular Liver Biopsy: A Randomized Double Blind Placebo Controlled Trial
Status: COMPLETED
Conditions: Cirrhosis|Chronic Hepatitis|Anxiety
Interventions: PROCEDURE: transjugular liver biopsy|DRUG: placebo|DRUG: midazolam|DRUG: midazolam + pethidine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lymph Node Involvement Using Extended Pelvic Lymphadenectomy in Clinically Localized Prostate Cancer
Status: COMPLETED
Conditions: Secondary Malignant Neoplasm of Lymph Node|Prostatic Neoplasms
Interventions: PROCEDURE: Radical Prostatectomy|PROCEDURE: Extended Lymphadenectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Efficacy of Adipose Derived Stem Cells for Congestive Heart Failure
Status: WITHDRAWN
Conditions: Ischemic Congestive Heart Failure
Interventions: PROCEDURE: Fat Harvesting and Implantation of Adipose Derived Stem Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resuscitative Endovascular Balloon Occlusion of the Aorta in Non-traumatic Out of Hospital Cardiac Arrest
Status: RECRUITING
Conditions: Cardiac Arrest
Interventions: PROCEDURE: REBOA|PROCEDURE: usual procedure according to guidelines
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Detection and Volumetry of Pulmonary Nodules on Ultra-low Dose Chest CT Scan With Deeplearning Image Reconstruction Algorithm (DLIR)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pulmonary Nodules, Multiple
Interventions: RADIATION: ULD CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Iron Isomaltide for Iron-deficiency Anemia Patients With Locally Advanced Nasopharyngeal Carcinoma
Status: RECRUITING
Conditions: Nasopharyngeal Carcinoma|Iron-deficiency|Anemia
Interventions: DRUG: Iron Isomaltoside 1000|DRUG: Polysaccharide Iron Complex Pill|RADIATION: Intensity-modulated radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Multicenter Study of the Safety and Efficacy of Adalimumab in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Status: COMPLETED
Conditions: Psoriasis
Interventions: DRUG: placebo for adalimumab|DRUG: adalimumab|DRUG: adalimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Pharmacokinetics (PK) and Tolerability Study of a Novel Drug for Treatment of Bacterial Infections
Status: COMPLETED
Conditions: Gram-negative Bacterial Infection
Interventions: DRUG: AN3365|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Echocardiographic Assessment of Ventricular Strain During a Healthy Pregnancy in the First, Second, and Third Trimester.
Status: UNKNOWN
Conditions: Echocardiography|Pregnancy Related Conditions, Unspecified, First Trimester|Pregnancy Related Conditions, Unspecified, Second Trimester|Pregnancy Related Conditions, Unspecified, Third Trimester|Ventricle Remodeling
Interventions: DIAGNOSTIC_TEST: 2D Echocardiography
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Multi Centre Study to Determine the Feasibility of Using an Integrated Consent Model to Compare Standard of Care Administration Schedules of G-CSF (Filgrastim) for Primary Prophylaxis of Chemotherapy-Induced Febrile Neutropenia in Early Stage Breast Cancer (React-G Study)
Status: COMPLETED
Conditions: Early Stage Breast Cancer
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Gemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic Cancer
Status: COMPLETED
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine|DRUG: Taxotere|DRUG: Xeloda|DRUG: Cisplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time
Status: COMPLETED
Conditions: Sleep|Sleep Disturbance
Interventions: DEVICE: Elemind Neuromodulation (ENMod)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: LeadHer, a Gender-specific Teen Pregnancy Prevention Curriculum for Girls 15-19
Status: COMPLETED
Conditions: Teenage Pregnancy
Interventions: BEHAVIORAL: LeadHer|BEHAVIORAL: Sassy Science
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Bioavailability Study of CoQ10 Formulations in Healthy Elderly Adults
Status: COMPLETED
Conditions: Bioavailability of Coenzyme Q10
Interventions: DIETARY_SUPPLEMENT: Single dose intervention with Standard product (SP)|DIETARY_SUPPLEMENT: Single dose intervention with Comparative product (CP)|DIETARY_SUPPLEMENT: Single dose intervention with Investigational product (IP)|DIETARY_SUPPLEMENT: Multiple dose intervention with Standard product (SP)|DIETARY_SUPPLEMENT: Multiple dose intervention with Comparative product (CP)|DIETARY_SUPPLEMENT: Multiple dose intervention with Investigational product (IP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Evaluation of Preoperative Submucosal Dexamethasone in Third Molar Surgery
Status: COMPLETED
Conditions: Impacted Third Molar Tooth
Interventions: DRUG: dexamethasone acetate|DRUG: submucosal dexamethasone injection|PROCEDURE: Third molar surgery|DRUG: Amoxicillin and paracetamol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: AI-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis
Status: RECRUITING
Conditions: Atrophic Gastritis|Artificial Intelligence|Endoscopy
Interventions: DIAGNOSTIC_TEST: Diagnostic Test: The diagnosis of Artificial Intelligence and endosopists
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Ultra High Dose Diuretics to Treat Heart Failure
Status: ENROLLING_BY_INVITATION
Conditions: Heart Failure; With Decompensation
Interventions: DRUG: Bumetanide|DRUG: Furosemide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Carvedilol in HF With Preserved EF
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Beta Blocker|Myocardial Strain
Interventions: DRUG: Carvedilol|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate Cancer
Status: NOT_YET_RECRUITING
Conditions: Advanced Prostate Cancer
Interventions: DIAGNOSTIC_TEST: Ga 68 PSMA-11 PET|DIAGNOSTIC_TEST: 18F-DCFPyL PET|DIAGNOSTIC_TEST: FDG PET
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment
Status: COMPLETED
Conditions: Neurodegenerative Diseases|Cognitive Decline|Parkinson Disease Dementia|Alzheimer Disease|Multiple Sclerosis
Interventions: DEVICE: Vespa software
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Individualized Physiotherapy and Activity Coaching for Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: Individualized behavioural physical activity intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families
Status: ACTIVE_NOT_RECRUITING
Conditions: Hereditary Breast Carcinoma|Hereditary Ovarian Carcinoma|Lynch Syndrome
Interventions: BEHAVIORAL: Behavioral Dietary Intervention|OTHER: E-mail|BEHAVIORAL: Exercise Intervention|OTHER: Health Promotion and Education|OTHER: Internet-Based Intervention|OTHER: Questionnaire Administration|BEHAVIORAL: Telephone-Based Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Platelet Rich Plasma in Skin Graft Take for Patients With Post Burn Raw Areas
Status: NOT_YET_RECRUITING
Conditions: Skin Burn
Interventions: PROCEDURE: PRP in skin grafts|PROCEDURE: conventional methods in skin grafts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Estimation of Level of ERAP1 Expression in Lesional and Non Lesional Skin of Psoraitic Patients and Healthy Controls.
Status: COMPLETED
Conditions: Psoriasis
Interventions: DIAGNOSTIC_TEST: RT-PCR for ERAP1 detection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Study of the Safety and Local Tolerability of Intranasal Gel Formulations of XF-73
Status: COMPLETED
Conditions: Staphylococcal Infection
Interventions: OTHER: Placebo|DRUG: XF-73 in 2% Klucel gel|DRUG: XF-73 in 4% Klucel gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Blood Ozonization in Patients With SARS-CoV-2 Respiratory Failure
Status: UNKNOWN
Conditions: SARS-CoV-2 Respiratory Failure
Interventions: PROCEDURE: Medical Ozone procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma in the Era of Immunotherapy
Status: RECRUITING
Conditions: Adjuvant Radiotherapy
Interventions: RADIATION: Adjuvant radiotherapy|OTHER: Observation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Drug 1 (Enzalutamide) Plus Drug 2 (Relacorilant) for Patients With Prostate Cancer
Status: ACTIVE_NOT_RECRUITING
Conditions: Prostate Cancer
Interventions: DRUG: Enzalutamide|DRUG: Relacorilant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Web-Based Mindful Breastfeeding Program During Pregnancy on Postpartum Breastfeeding
Status: NOT_YET_RECRUITING
Conditions: Mindfulness|Breast Feeding|Psychological Well-Being
Interventions: BEHAVIORAL: Mindful Breastfeeding Program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Early Biomarker Kidney Injury Assessment After Acumen Directed Fluid Management in Cardiac Surgery
Status: NOT_YET_RECRUITING
Conditions: Renal Injury|Acute Kidney Injury
Interventions: OTHER: Goal Directed Fluid Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: Sequential Intravesical Gemcitabine and Docetaxel for Rescue Therapy in BCG Unresponsive Non-muscle Invasive Bladder Cancer Patients
Status: NOT_YET_RECRUITING
Conditions: Bladder Cancer|BCG|Gemcitabine|Docetaxel|Intravesical Instillation
Interventions: DRUG: Intravesical Solution
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Efficacy Study of the Embryo Transfer Catheter
Status: COMPLETED
Conditions: Infertility (IVF Patients)
Interventions: DEVICE: Cook K-SOFT-5100 catheter|DEVICE: Frydman classical catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
Status: COMPLETED
Conditions: Adult Rhabdomyosarcoma|Childhood Alveolar Rhabdomyosarcoma|Childhood Embryonal Rhabdomyosarcoma|Metastatic Childhood Soft Tissue Sarcoma|Stage IV Adult Soft Tissue Sarcoma|Untreated Childhood Rhabdomyosarcoma
Interventions: BIOLOGICAL: Cixutumumab|DRUG: Cyclophosphamide|BIOLOGICAL: Dactinomycin|DRUG: Doxorubicin Hydrochloride|DRUG: Etoposide|DRUG: Ifosfamide|DRUG: Irinotecan Hydrochloride|OTHER: Laboratory Biomarker Analysis|DRUG: Temozolomide|DRUG: Vincristine Sulfate Liposome
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Treatment of Moderate to Severe Plaque Psoriasis
Status: NOT_YET_RECRUITING
Conditions: Plaque Psoriasis
Interventions: DRUG: TQH3906 capsules|DRUG: Placebo of TQH3906 capsules
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Management of Resistant Hypertension in Kidney Transplant Patients Using Chlorthalidone
Status: WITHDRAWN
Conditions: Resistant Hypertension in Kidney Transplant Patients
Interventions: DRUG: Chlorthalidone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure
Status: UNKNOWN
Conditions: Renal Calculi
Interventions: DEVICE: SF-URS with automatic control of RPP|DEVICE: conventional F-URS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v8|Stage IVA Colorectal Cancer AJCC v8|Stage IVB Colorectal Cancer AJCC v8|Stage IVC Colorectal Cancer AJCC v8|Unresectable Carcinoma
Interventions: DRUG: Binimetinib|DRUG: Palbociclib|DRUG: Trifluridine and Tipiracil Hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RESPIRARE - Efficacy and Safety of Cudetaxestat in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Status: UNKNOWN
Conditions: Idiopathic Pulmonary Fibrosis
Interventions: DRUG: Cudetaxestat (BLD-0409)|DRUG: Control: Matching Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD)
Status: COMPLETED
Conditions: Dermatitis, Atopic
Interventions: DRUG: Dupilumab|DRUG: Matching Placebo|OTHER: Background Treatment: Topical Corticosteroids|OTHER: Background Treatment: Moisturizers
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease
Status: ENROLLING_BY_INVITATION
Conditions: Legg Calve Perthes Disease
Interventions: PROCEDURE: Osteotomy + Long Term Non-Weight Bearing|PROCEDURE: Osteotomy + Short Term Non-Weight Bearing|PROCEDURE: Nonoperative Observation|PROCEDURE: Multiple Epiphyseal Drilling
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Interaction Study of Clopidogrel 600/150 mg Given Alone or Concomitantly With Omeprazole 80 mg in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Clopidogrel|DRUG: Placebo|DRUG: Omeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)
Status: COMPLETED
Conditions: Prostate Cancer
Interventions: DRUG: Testosterone cypionate|DRUG: Testosterone Enanthate|DRUG: Abiraterone acetate|DRUG: Enzalutamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics of Co-administration of Seretide 250 Diskus (HCP0910) and Spiriva Capsule for Inhalation (HGP1011)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: HCP0910 and HGP1011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester.
Status: RECRUITING
Conditions: Asherman Syndrome|Abortion Late
Interventions: DRUG: Hyaluronic Acid 20 MG/ML Injectable Solution|OTHER: Dilation and curretage
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Develop a Multi-disciplinary Approach for a Personalized Prenatal Diagnostics and Care for Twin Pregnancies
Status: UNKNOWN
Conditions: Prenatal Disorder|Premature Birth|Twin Pregnancy With Antenatal Problem|Twin; Pregnancy, Affecting Fetus or Newborn|Twin Pregnancy, Antepartum Condition or Complication|Twin Dichorionic Diamniotic Placenta|Twin Monochorionic Monoamniotic Placenta
Interventions: OTHER: TTTS cases are treated by intra-uterine laser for separation.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs
Status: ACTIVE_NOT_RECRUITING
Conditions: Hypertension,Pulmonary
Interventions: BIOLOGICAL: Placebo followed by Autologous EPCs transfected with human eNOS|BIOLOGICAL: Autologous EPCs transfected with human eNOS followed by Placebo|BIOLOGICAL: Autologous EPCs transfected with human eNOS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood
Status: ACTIVE_NOT_RECRUITING
Conditions: Copy Number Abnormality|Prenatal Diagnosis|Genetic Disease
Interventions: DIAGNOSTIC_TEST: Whole Fetal Cell (WFC) Testing
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cycle Control and Safety of E2-DRSP
Status: COMPLETED
Conditions: Contraceptive, Oral, Hormonal
Interventions: DRUG: E2/DRSP (BAY 86-4891) dose 1 (SH T04984E)|DRUG: E2/DRSP (BAY 86-4891) dose 2 (80458739)|DRUG: E2/DRSP (BAY 86-4891) dose 3 (80458755)|DRUG: E2/DRSP (BAY 86-4891) dose 4 (80458720)|DRUG: E2/DRSP (BAY 86-4891) dose 5 (80458712)|DRUG: DRSP (ZK 30595) dose 1 (SH T04984F)|DRUG: DRSP (ZK 30595) dose 2 (80458690)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of HFNC and COT to Diaphragm Function of Post-upper Abdominal Surgery Patients
Status: COMPLETED
Conditions: Post Abdominal Surgery
Interventions: PROCEDURE: HFNC; COT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: First Trimester Screening for Preeclampsia and Intrauterine Growth RestrIction Using Three Dimensional Doppler Angiography
Status: COMPLETED
Conditions: Pre-Eclampsia
Interventions: DEVICE: Ultrasound|BIOLOGICAL: Blood sample collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery
Status: TERMINATED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|DRUG: everolimus|PROCEDURE: therapeutic conventional surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Activity, Alzheimer's Disease and Cognition Relative to APOE Genotype
Status: ACTIVE_NOT_RECRUITING
Conditions: Healthy|Dementia|Alzheimer Disease|Physical Activity
Interventions: BEHAVIORAL: Physical Activity Condition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Analgesic Effect of Adductor Canal Block With and Without Dexamethasone for Knee Arthroscopy
Status: COMPLETED
Conditions: Postoperative Analgesia
Interventions: DRUG: Saline Solution|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Advanced Hepatocellular Carcinoma (MK-3475-224/KEYNOTE-224)
Status: COMPLETED
Conditions: Hepatocellular Carcinoma
Interventions: BIOLOGICAL: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Immediate Effect and Substantivity of the Essential Oils Without Alcohol on the Oral Biofilm in Situ
Status: UNKNOWN
Conditions: Biofilms|Substantivity|Oils, Essential
Interventions: DRUG: essential oils|DRUG: essential oils without mouthwash|DRUG: sterile water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Precise Use of Lidocaine Cream to Treat Primary Premature Ejaculation
Status: UNKNOWN
Conditions: Premature Ejaculation
Interventions: DRUG: Lidocaine cream|DRUG: Lidocaine cream
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens
Status: RECRUITING
Conditions: Cataracts
Interventions: DEVICE: Test IOL Model DEN00V|DEVICE: Control IOL Model DCB00
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Effects of VR and White Noise During Arthroscopy (VR/WN_ ART)
Status: NOT_YET_RECRUITING
Conditions: Arthroscopic Surgical Procedures
Interventions: DEVICE: Virtual Reality Glasses group|DEVICE: white noise group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma
Status: COMPLETED
Conditions: Refractory Neuroblastoma|Soft Tissue Cancer
Interventions: DRUG: HITS|DRUG: Naxitamab + GM-CSF cycles|DRUG: NICE
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength and Heart Rate Variability
Status: NOT_YET_RECRUITING
Conditions: Healthy
Interventions: OTHER: Inspiratory muscle training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Implementing Prevention Plus for Childhood Overweight and Obesity in Food Secure and Insecure Families
Status: COMPLETED
Conditions: Obesity|Childhood Obesity
Interventions: BEHAVIORAL: Prevention Plus +|BEHAVIORAL: Prevention Plus -
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation
Status: WITHDRAWN
Conditions: Cerebral Ischemia
Interventions: DRUG: cafedrine/theodrenaline, urapidil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Individualized Sensitivity-Directed Chemotherapy Versus DTIC
Status: UNKNOWN
Conditions: Melanoma
Interventions: DRUG: DTIC (dacarbazine)|DRUG: paclitaxel + cisplatin|DRUG: treosulfan + cytarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis
Status: COMPLETED
Conditions: Aggressive Periodontitis, Generalized
Interventions: PROCEDURE: Full-mouth ultrasonic debridement|DRUG: Amoxicillin 500mg|DRUG: Metronidazole 400mg|DRUG: Clarithromycin 500mg|PROCEDURE: Single application of PDT|PROCEDURE: Repeated application of PDT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Sympathetic Ganglion Block
Status: NOT_YET_RECRUITING
Conditions: Chronic Pain|Neuropathic Pain|Complex Regional Pain Syndromes|Post Herpetic Neuralgia|Post Laminectomy Syndrome
Interventions: DEVICE: Ultrasound|DEVICE: Fluoroscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
Status: COMPLETED
Conditions: Sickle Cell Disease|Thalassemia|Anemia|Granuloma|Wiskott-Aldrich Syndrome|Chediak Higashi Syndrome|Osteopetrosis|Neutropenia|Thrombocytopenia|Hurler Disease|Niemann-Pick Disease|Fucosidosis
Interventions: PROCEDURE: Hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of BI 44370 TA Orally Applied as Tablets on the Pharmacokinetics of Orally Administered Midazolam Solution in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Midazolam|DRUG: BI 44370 low dose|DRUG: BI 44370 medium dose|DRUG: BI 44370 high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease
Status: COMPLETED
Conditions: Dry Eye Disease
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Safety and Efficacy Study of BCD-080 Compared to Clexan for Deep Vein Thrombosis Prophylaxis at Orthopedic Surgeries
Status: COMPLETED
Conditions: Deep Vein Thrombosis
Interventions: DRUG: Sodium Enoxaparine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: The Impact of Dupilumab on Quality of Life in Moderate to Severe Atopic Dermatitis Patients
Status: COMPLETED
Conditions: Atopic Dermatitis|Atopic Dermatitis Eczema
Interventions: DRUG: Dupilumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia
Status: COMPLETED
Conditions: Idiopathic Hypersomnia|Narcolepsy Without Cataplexy
Interventions: DRUG: Modafinil|DRUG: Amphetamine-Dextroamphetamine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma|Metastatic Melanoma|Recurrent Melanoma|Stage III Cutaneous Melanoma AJCC v7|Stage IIIA Cutaneous Melanoma AJCC v7|Stage IIIB Cutaneous Melanoma AJCC v7|Stage IIIC Cutaneous Melanoma AJCC v7|Stage IV Cutaneous Melanoma AJCC v6 and v7|Unresectable Melanoma
Interventions: BIOLOGICAL: Ipilimumab|BIOLOGICAL: Sargramostim
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Speeding Recovery From Pain and Opioid Use
Status: WITHDRAWN
Conditions: Pain, Postoperative|Breast Cancer|Opioid Use|Surgery
Interventions: DRUG: Local infiltration of bupivacaine|DRUG: Pectoralis Nerve block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: The Effect of Time Window for Umbilical Cord Clamping During Cesareans on Offspring Hemoglobin and Maternal Blood Loss
Status: ACTIVE_NOT_RECRUITING
Conditions: Delayed Cord Clamping|Hemoglobin|Blood Loss
Interventions: PROCEDURE: Delayed cord clamping (30s)|PROCEDURE: Delayed cord clamping (60s)|PROCEDURE: Delayed cord clamping (90s)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Endocuff Vision Assisted vs. Standard Polyp Resection in the Colorectum
Status: COMPLETED
Conditions: Colon Polyp
Interventions: DEVICE: Endocuff Vision assisted polypectomy|OTHER: Standard polypectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)
Status: COMPLETED
Conditions: Diabetes|Diabetes Mellitus, Type 2
Interventions: DRUG: Semaglutide 0.5 mg|DRUG: Semaglutide 1.0 mg|DRUG: Sitagliptin placebo|DRUG: Sitagliptin|DRUG: Semaglutide placebo 0.5 mg|DRUG: Semaglutide placebo 1.0 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Trial of Pemetrexed Versus Erlotinib in Pretreated Patients With Non Small Cell Lung Cancer (NSCLC)
Status: COMPLETED
Conditions: Non Small Cell Lung Cancer
Interventions: DRUG: Erlotinib (Tarceva)|DRUG: Pemetrexed (Alimta)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Environmental and Acceptance-Based Innovations for Weight Loss Maintenance
Status: COMPLETED
Conditions: Obesity|Overweight|Weight Loss
Interventions: BEHAVIORAL: Behavior Therapy for Weight Loss|BEHAVIORAL: Behavior Therapy + Environment|BEHAVIORAL: Acceptance-based Behavior Therapy + Environment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Idiopathic Angioedema With Xolair as Add-on Therapy
Status: COMPLETED
Conditions: Idiopathic Angioedema
Interventions: DRUG: Omalizumab|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Effects of Intranasal Oxytocin and Vasopressin on Social Behavior and Decision Making
Status: UNKNOWN
Conditions: Healthy
Interventions: DRUG: Intranasal Oxytocin|DRUG: Intranasal vasopressin|DRUG: Intranasal placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Use of Non-invasive Optical Analysis in Neurosurgery
Status: RECRUITING
Conditions: Brain Tumour|Glioma|Meningioma|Brain Metastases|Schwannoma
Interventions: DEVICE: Intra-operative multispectral / hyperspectral analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Lapatinib for Treatment of Ductal Carcinoma In Situ (DCIS) of the Breast
Status: TERMINATED
Conditions: Ductal Carcinoma in Situ
Interventions: DRUG: lapatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Randomized, Double-blind, Multicenter, Phase III Study to Evaluate the Efficacy and Safety of Combination of Fimasartan/Rosuvastatin in Comparison to Each Component Administered Alone in Patients With Essential Hypertension and Dyslipidemia
Status: COMPLETED
Conditions: Essential Hypertension, Dyslipidemia
Interventions: DRUG: Fimasartan and Rosuvastatin|DRUG: Fimasartan|DRUG: Rosuvastatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT