pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Optimizing Physical Activity Outcomes After Total Knee Arthroplasty
Status: COMPLETED
Conditions: Total Knee Arthroplasty|Osteoarthritis
Interventions: BEHAVIORAL: Physical Activity Behavior Intervention|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Paediatric EVICEL® Soft Tissue and Parenchymal Organ Bleeding Study
Status: COMPLETED
Conditions: Hemorrhage|Soft Tissue Bleeding
Interventions: BIOLOGICAL: EVICEL® Fibrin Sealant|DEVICE: SURGICEL® Absorbable Hemostat
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Programs to Support You During Chemotherapy (Pro-You)
Status: COMPLETED
Conditions: Depressive Symptoms|Fatigue|Psychosocial Effects of Cancer and Its Treatment|Stage IIA Colon Cancer|Stage IIA Rectal Cancer|Stage IIB Colon Cancer|Stage IIB Rectal Cancer|Stage IIC Colon Cancer|Stage IIC Rectal Cancer|Stage IIIA Colon Cancer|Stage IIIA Rectal Cancer|Stage IIIB Colon Cancer|Stage IIIB Rectal Cancer|Stage IIIC Colon Cancer|Stage IIIC Rectal Cancer|Stage IVA Colon Cancer|Stage IVA Rectal Cancer|Stage IVB Colon Cancer|Stage IVB Rectal Cancer
Interventions: BEHAVIORAL: Yoga Skills Training (YST)|OTHER: questionnaire administration|OTHER: fatigue and depressive symptom assessment and management|OTHER: psychological stress assessment|OTHER: laboratory biomarker analysis|OTHER: Attention Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Safety and Efficacy Study of Etanercept (Enbrel®) In Children With Systemic Onset Juvenile Rheumatoid Arthritis
Status: TERMINATED
Conditions: Juvenile Rheumatoid Arthritis
Interventions: DRUG: Etanercept|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery
Status: ACTIVE_NOT_RECRUITING
Conditions: Metastatic Colorectal Carcinoma|Metastatic Malignant Neoplasm in the Liver|Metastatic Malignant Neoplasm in the Lung|Recurrent Colorectal Carcinoma|Resectable Colorectal Carcinoma|Stage IV Colorectal Cancer AJCC v7|Stage IVA Colorectal Cancer AJCC v7|Stage IVB Colorectal Cancer AJCC v7
Interventions: DRUG: Chemotherapy|OTHER: Laboratory Biomarker Analysis|PROCEDURE: Metastasectomy|OTHER: Quality-of-Life Assessment|PROCEDURE: Therapeutic Conventional Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Assess the Effect of E-OA-07 on Acute Pain Response in Subjects Suffering From Knee OA
Status: COMPLETED
Conditions: Osteoarthritis of Knee
Interventions: OTHER: E-OA-07 (Lanconone)|DRUG: Ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aging and Immobilisation on Muscle
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: 2 weeks of unilateral immobilisation and 4 weeks of resistance training|OTHER: 2 weeks of unilateral immobilisation and 4 weeks of resistance training
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of YH004 (4-1BB Agonist Antibody) in Advanced Solid Tumors And Relapsed Or Refractory Non-Hodgkin Lymphoma
Status: RECRUITING
Conditions: Advanced Solid Tumors|Relapsed Or Refractory Non-Hodgkin Lymphoma
Interventions: DRUG: YH004
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of a Fast-track Knee Arthroplasty Concept
Status: COMPLETED
Conditions: Knee Arthropathy|Postoperative Pain|Postoperative Complications
Interventions: PROCEDURE: local infiltration analgesia|PROCEDURE: regional-anaesthesiological catheter analgesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Maternal Voice on Alleviating Pain in Premature Undergoing Heel Lance Procedure and Enhancing Mother-Infant Bonding
Status: COMPLETED
Conditions: Infant, Extremely Premature|Voice|Pain|Bonding
Interventions: OTHER: Maternal voice
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring
Status: COMPLETED
Conditions: Endothelial Dysfunction|Childhood Obesity
Interventions: OTHER: Parental questionnaires|OTHER: Blood sample|OTHER: Urine sample|OTHER: Anthropometric measurements|OTHER: Ultrasound|OTHER: EndoPAT|OTHER: Faces Pain Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Pegylated Interferon, Ribavirin, Telaprevir in Hepatitis C Virus Infection in Orthotopic Liver Transplant Recipients
Status: TERMINATED
Conditions: Hepatitis C
Interventions: DRUG: Peginterferon alfa-2a|DRUG: Ribavirin|DRUG: telaprevir
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Weight Bearing Status Post-hip Arthroscopy
Status: ENROLLING_BY_INVITATION
Conditions: Hip Impingement Syndrome|Acetabular Labral Tear
Interventions: OTHER: Weight Bearing as tolerated (WBAT) immediately following surgery.|OTHER: Flat foot weight bearing (FFWB) immediately following surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI
Status: COMPLETED
Conditions: Cognition Disorder|Attention Deficit Disorder|Traumatic Brain Injury
Interventions: DRUG: Methylphenidate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fluorouracil, Leucovorin, Gemcitabine, and Cisplatin in Treating Patients With Metastatic or Unresectable Adenocarcinoma of the Urothelium or Urachal Remnant
Status: ACTIVE_NOT_RECRUITING
Conditions: Bladder Cancer|Urethral Cancer|Urachal Cancer
Interventions: DRUG: 5-Fluorouracil (5-FU)|DRUG: Leucovorin|DRUG: Cisplatin|DRUG: Gemcitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Alcohol on Food Reward
Status: COMPLETED
Conditions: Obesity|Body Weight
Interventions: OTHER: Orange juice|OTHER: maltodextrin|OTHER: Vodka|OTHER: butter cake MSF|OTHER: butter cake consumption
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: In Vivo Proof-of-principle Study of Raman Spectroscopy in Trial Participants With Bladder Tumours
Status: UNKNOWN
Conditions: Endoscopic Bladder Cancer Diagnosis With Raman
Interventions: DIAGNOSTIC_TEST: Raman Spectrometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Exopulse Mollii Suit, Spasticity & Tissue Oxygenation
Status: COMPLETED
Conditions: Multiple Sclerosis
Interventions: DEVICE: Exopulse Mollii Suit|DEVICE: Exopulse Mollii suit (sham)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Examination of Breast Cancer Cells of Pre-menopausal and Post-menopausal Women Before and After Exposure to Tamoxifen or Fulvestrant.
Status: TERMINATED
Conditions: Breast Cancer
Interventions: DRUG: Fulvestrant|DRUG: Tamoxifen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study Investigating the Distribution and Metabolism of Three 14C-labeled Radioactive Study Compounds
Status: COMPLETED
Conditions: Healthy Volunteers|Type 2 Diabetes
Interventions: DRUG: NNC0113-6861|DRUG: NNC0113-6860|DRUG: NNC0113-6891
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MLS101 in Healthy Participants
Status: RECRUITING
Conditions: Healthy Volunteers
Interventions: DRUG: Psilocybin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Immunogenicity and ex Vivo Efficacy of Pfs25-IMX313/Matrix-M in Healthy Volunteers in Bagamoyo, Tanzania.
Status: UNKNOWN
Conditions: Malaria,Falciparum
Interventions: BIOLOGICAL: Pfs25-IMX313 (10ug)/Matrix-M (50ug)|BIOLOGICAL: Pfs25-IMX313 (50ug)/Matrix-M (50ug)|BIOLOGICAL: Pfs25-IMX313 (50ug)/Matrix-M (50ug) & Pfs25-IMX313 (10ug)/Matrix-M (50ug)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Levomilnacipran ER in Adolescent Participants With Major Depressive Disorder
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Placebo|DRUG: Levomilnacipran|DRUG: Fluoxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)
Status: RECRUITING
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: single dose of CNCT19
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma
Status: COMPLETED
Conditions: Metastatic Melanoma
Interventions: BIOLOGICAL: Melanoma Reactive TIL|DRUG: Cyclophosphamide|BIOLOGICAL: IL-2|DRUG: Fludarabine|RADIATION: 1200 total body irradiation (TBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver Cirrhosis
Status: RECRUITING
Conditions: Antibiotic Toxicity|Liver Cirrhosis|Renal Insufficiency|Ceftriaxone Overdose|Ascites Hepatic|Infection, Bacterial
Interventions: OTHER: No intervention
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: High Intensity Focused Ultrasound (HIFU) Ablation System Study
Status: SUSPENDED
Conditions: Atrial Fibrillation
Interventions: DRUG: propafenone|DRUG: flecainide|DRUG: dofetilide|DRUG: sotolol|DEVICE: Pulmonary vein ablation|DRUG: Amiodarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Hemostatic Agent to Suture in Terms of Hemostatic Function and Preservation of Ovarian Function
Status: RECRUITING
Conditions: Benign Ovarian Cyst
Interventions: PROCEDURE: Hemostatic agent (EVICEL®) application during laparoscopic ovarian cystectomy|PROCEDURE: suturing with barbed sutures during laparoscopic ovarian cystectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Development and Clinical Validation of Ketogen-based Therapeutic Diet for Pancreaticobiliary Cancer Patients
Status: COMPLETED
Conditions: Ketogen-based Therapeutic Diet|Pancreaticobiliary Cancer
Interventions: DIETARY_SUPPLEMENT: Ordinary Diet|DIETARY_SUPPLEMENT: Modified Atkin's Diet|DIETARY_SUPPLEMENT: Ketogenic Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: CD19CD22 CAR-T Therapy in Patients With High-Risk B Acute Lymphoblastic Leukemia (B-ALL).
Status: RECRUITING
Conditions: B Acute Lymphoblastic Leukemia|Ph-Negative ALL|High Risk Acute Lymphoblastic Leukemia
Interventions: DRUG: Azacitidine Injection|DRUG: Venetoclax|DRUG: CD19CD22 CAR-T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Changes in Insulin Sensitivity in Healthy Volunteers Taking Tenofovir Alafenamide (TAF)-Containing Antiretroviral Medication
Status: COMPLETED
Conditions: Insulin Resistance
Interventions: DRUG: F/TAF|DRUG: E/C/F/TAF|DRUG: R/F/TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Manual Myofascial Release Versus Instrument Assisted Soft Tissue Mobilization (IASTM) in Patients With Chronic Neck Pain"
Status: UNKNOWN
Conditions: Chronic Neck Pain
Interventions: PROCEDURE: Instrument Assisted Soft tissue Mobilization|PROCEDURE: Manual Myofascial Release
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
Status: RECRUITING
Conditions: Endothelial Dysfunction
Interventions: DRUG: Galantamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Immediate Loading of 4 Guided Implants Supporting a Maxillary Overdenture Using a Novaloc TiN Retention System
Status: ACTIVE_NOT_RECRUITING
Conditions: Immediate Dental Implant Loading|Denture, Complete
Interventions: DEVICE: NOVALOC TiN retained maxillary overdenture
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: oPen Versus RobotIc retrOmuscular Repair in Medium to Large Ventral Hernias
Status: NOT_YET_RECRUITING
Conditions: Ventral Hernia|Incisional Hernia|Abdominal Wall Defect
Interventions: PROCEDURE: Robotically-assisted ventral hernia repair (RVHR)|PROCEDURE: Open ventral hernia repair (OVHR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Continous Positive Airway Pressure (CPAP) in Hypertrophic Cardiomyopathy
Status: COMPLETED
Conditions: Non-obstructive Hypertrophic Cardiomyopathy|Obstructive Hypertrophic Cardiomyopathy
Interventions: DEVICE: CPAP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Use of a Novel Microbicidal Liquid Polymer for the Reduction of Pin Track Infection
Status: COMPLETED
Conditions: Infection|Post-operative Care
Interventions: DEVICE: Novel Microbicidal Liquid Polymer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission
Status: RECRUITING
Conditions: Acute Myeloid Leukemia (AML) in Remission
Interventions: DRUG: Azacitidine|DRUG: Venetoclax|OTHER: Supportive care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake
Status: COMPLETED
Conditions: Appetitive Behavior
Interventions: OTHER: Micellar Casein (#1)|OTHER: Micellar Casein (#2)|OTHER: Calcium Caseinate|OTHER: Sodium Caseinate|OTHER: Milk Protein Isolate|OTHER: Pure Protein Blend|OTHER: Whey Protein Isolate|OTHER: Native Whey Protein Isolate|OTHER: Soy Protein|OTHER: Pea Protein|OTHER: Native Whey: Micellar Casein (50:50) blend|OTHER: Carbohydrate Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer
Status: RECRUITING
Conditions: Metastatic Breast Cancer
Interventions: DRUG: PMD-026|DRUG: fulvestrant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility of the Ultravision™ System in Low Pressure Laparoscopic Cholecystectomy Compared to Airseal® IFS
Status: UNKNOWN
Conditions: Laparoscopic Cholecystectomy
Interventions: DEVICE: Smoke management during laparoscopic cholecystectomy using the Ultravision™ System|DEVICE: Smoke management during laparoscopic cholecystectomy using the Airseal® iFS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IFN-DLI for Relapsed Acute Leukemia After Allo-SCT
Status: COMPLETED
Conditions: Leukemia
Interventions: DRUG: Interferon alpha-2B (IFN-α) 3 million units (MU) subcutaneous daily
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Pevonedistat on the Corrected QT (QTc) Interval in Participants With Advanced Solid Tumors
Status: COMPLETED
Conditions: Advanced Solid Neoplasm
Interventions: DRUG: Pevonedistat|DRUG: Docetaxel|DRUG: Carboplatin|DRUG: Paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Reminders on Adherence
Status: COMPLETED
Conditions: Diabetes|Hypertension
Interventions: BEHAVIORAL: Prediction mailing|BEHAVIORAL: Commitment mailing|BEHAVIORAL: Reminder|BEHAVIORAL: Anonymity|BEHAVIORAL: Identification
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
Interventions: DRUG: BOTOX|DRUG: Placebo for BOTOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Acupuncture on Incomplete Fallopian Tube Obstructive Infertility: Study Protocol for Trial
Status: UNKNOWN
Conditions: Female Infertility Due to Occlusion of Fallopian Tube
Interventions: OTHER: acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Proof of Concept Study of Rilzabrutinib in Adult Patients With Moderate-to-severe Atopic Dermatitis
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Placebo|DRUG: Rilzabrutinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of the Ease of Use and Correct Use of Placebo ELLIPTA® Inhaler in Subjects With Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Placebo ELLIPTA inhaler|OTHER: Questionnaire
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Improving Diabetic Patient Health Through Assistive-Reading Technology
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetes Mellitus, Type 2|Health Knowledge, Attitudes, Practice|Literacy
Interventions: OTHER: GogyUp Reader
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reducing Postpartum Hemorrhage After Vaginal Delivery
Status: NOT_YET_RECRUITING
Conditions: Postpartum Hemorrhage|Vaginal Delivery
Interventions: OTHER: Integrated Improvement strategies
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety, Tolerability, Pharmacokinetics of Single Rising Oral Doses of BI 1181181 in Healthy Male Volunteers, Including Investigation of the Effect of Food on the Bioavailability of BI 1181181
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: BI 1181181|DRUG: BI 1181181, R|DRUG: BI 1181181, T2|DRUG: Placebo to BI 1181181|DRUG: BI 1181181, T1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Immune Response to an HIV DNA Plasmid Vaccine Prime Followed by Adenovirus Boost in HIV-uninfected Individuals
Status: COMPLETED
Conditions: HIV Infections
Interventions: BIOLOGICAL: VRC-HIVDNA-016-00-VP|BIOLOGICAL: VRCHIVADV014-00-VP
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)
Status: COMPLETED
Conditions: Glaucoma, Angle-closure, Primary, Acute
Interventions: DRUG: QPI-1007 Injection|DRUG: (including placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma
Status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma|Enteral Nutrition Therapy|Chemoradiotherapy
Interventions: DRUG: Enteral nutrition|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supreme LMA and Proseal LMA in Prone Anesthetized Patient
Status: UNKNOWN
Conditions: Inadequate or Impaired Breathing Pattern or Ventilation
Interventions: DEVICE: Supreme LMA|DEVICE: Proseal LMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose:
Clinical trial: Effect of a Transversus Abdominis Plane Block on Wound Healing, Stress, and Immune Response After a Cesarean Delivery
Status: NOT_YET_RECRUITING
Conditions: Postoperative Pain|Cesarean Section|Wound Heal
Interventions: DRUG: Postoperative pain management with acetaminophen|PROCEDURE: Bilateral TAP Block with levobupivacaine|PROCEDURE: Bilateral TAP Block with levobupivacaine and dexmedetomidine|DRUG: Postoperative pain management with tramadol|DRUG: Postoperative pain management with ketoprofen|DRUG: Postoperative pain management with ibuprofen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Infraclavicular or Supraclavicular Brachial Plexus Blocks for Elbow Surgery
Status: COMPLETED
Conditions: Cubital Tunnel Syndrome|Biceps Tendon Rupture
Interventions: PROCEDURE: Supraclavicular|PROCEDURE: Infraclavicular
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Operative Treatment of 2-fragment-fractures (AO 11-A3) of the Proximal Humerus in the Elderly: Cement Augmented Locking Plate Philos vs. Proximal Humerus Nail MultiLoc
Status: UNKNOWN
Conditions: Shoulder Fractures|Intramedullary|Bone Plates
Interventions: DEVICE: PhilosTM with augmentation (Depuy-Synthes)|DEVICE: MultiLoc®-Nail (Depuy-Synthes)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Trial of LIB-01 in Healthy Participants.
Status: COMPLETED
Conditions: Erectile Dysfunction
Interventions: DRUG: LIB-01|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telephone Versus Face-to-Face CBT in Treating People With Depression
Status: COMPLETED
Conditions: Depression
Interventions: BEHAVIORAL: Telephone-administered cognitive behavioral therapy (T-CBT)|BEHAVIORAL: Face-to-face administered CBT (FtF-CBT)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens
Status: COMPLETED
Conditions: Astigmatism
Interventions: DEVICE: stenfilcon A|DEVICE: etafilcon A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Feasibility Study - The Place of Surgical Management by Fatty Autograft in Patients With Healed Pelvic Eschar. Interest in Secondary Prevention.
Status: UNKNOWN
Conditions: Eschar
Interventions: PROCEDURE: Autograft fat
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Metronomic Oral Vinorelbine Plus Anti-PD-L1/Anti-CTLA4 ImmunothErapy in Patients With Advanced Solid Tumours
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Solid Tumours|Breast Cancer|Head and Neck Cancer|Cervix Cancer|Prostate Cancer
Interventions: DRUG: Durvalumab + Tremelimumab + metronomic Vinorelbine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease
Status: RECRUITING
Conditions: Moderately to Severely Active Crohn's Disease|Crohn Disease|Disease Crohn
Interventions: BIOLOGICAL: Vedolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Blood Levels and Effects of GSK1325756 in Healthy Adult Volunteers Aged 40 to 80 Years Old
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: GSK1325756|DRUG: Placebo tablet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Micronutrient Supplementation in in Paediatric Pulmonary Tuberculosis
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Zinc|DRUG: Micronutrient without zinc|DRUG: Micronutrient with zinc|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effects of L-Carnitine Injection in Patients Undergoing Hemodialysis
Status: UNKNOWN
Conditions: Cardiac Complications|Signs and Symptoms|Muscle Weakness|Anemia|Hypotension
Interventions: DRUG: L-Carnitine Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Cassia Cinnamon on Arterial Stiffness Parameters in Patients With Type 2 Diabetes Mellitus
Status: UNKNOWN
Conditions: Arterial Stiffness
Interventions: DIETARY_SUPPLEMENT: Cassia Cinnamon|OTHER: Calcined magnesia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Study for the Impact of Bio-absorbable Felt (NEOVEIL®) With Fibrin Sealant on Removal of Drainage Tube After Minimally Invasive Gastrectomy for Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DEVICE: bio-absorbable felt(NEOVEIL®)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Cognitive Behavioral Therapy for Patients With an Early Psychosis
Status: COMPLETED
Conditions: Psychosis|Schizophrenia|Depressive Symptoms|Self-esteem
Interventions: BEHAVIORAL: cognitive behavioral therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Of Dalbavancin Drug Levels Achieved In Hospitalized Adolescents Who Are Receiving Antibiotic Therapy For Bacterial Infections
Status: COMPLETED
Conditions: Bacterial Infections
Interventions: DRUG: Dalbavancin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose:
Clinical trial: Characterization of Mechanical Tissue Properties in Patients With Pancreatic, Liver, or Colon Cancer
Status: TERMINATED
Conditions: Colon Carcinoma|Liver and Intrahepatic Bile Duct Carcinoma|Pancreatic Carcinoma
Interventions: PROCEDURE: Biospecimen Collection|OTHER: Laboratory Biomarker Analysis|OTHER: Laboratory Procedure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety and Clinical Activity of KT-253 in Adult Patients With High Grade Myeloid Malignancies, Acute Lymphocytic Leukemia, Lymphoma, Solid Tumors
Status: RECRUITING
Conditions: Myeloid Malignancies|Acute Lymphocytic Leukemia|Lymphomas|Advanced Solid Tumors
Interventions: DRUG: KT-253
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Apatinib as Maintenance Therapy After First-line Chemotherapy(DC for 4 Cycles) in Postoperative Recurrence/Metastasis Progressive Gastric Cancer
Status: UNKNOWN
Conditions: Gastric Cancer
Interventions: DRUG: Apatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Safety Study of HPP593 in Subjects During and After Limb Immobilization
Status: TERMINATED
Conditions: Muscle Atrophy|Hypodynamia
Interventions: DRUG: HPP593|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori
Status: UNKNOWN
Conditions: Helicobacter-associated Gastritis
Interventions: DRUG: Nitazoxanide|DRUG: Metronidazole(MTZ)|DRUG: Omeprazole|DRUG: Clarithromycin|DRUG: Levofloxacin|DRUG: Doxicycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: To Determine the Efficacy of the TwinGuard in Oxygen Delivery During and Post Endoscopic Procedure
Status: COMPLETED
Conditions: Hypoxia|Hypercapnia
Interventions: DEVICE: TwinGuard|DEVICE: Standard endoscopic bite block|DEVICE: Standard nasal cannula|DEVICE: CO2 sample line
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Bilateral Erector Spinae Plane Block Versus Local Anesthetic Infiltration for Perioperative Analgesia in Spine Surgery.
Status: COMPLETED
Conditions: Pain, Postoperative|SPINAL Fracture|Spondylolisthesis
Interventions: PROCEDURE: ESP block|PROCEDURE: Wound infiltration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dopamine Release to Food Reward in Bulimia Nervosa
Status: UNKNOWN
Conditions: Bulimia Nervosa|Food Reward
Interventions: BEHAVIORAL: Food reward at baseline|BEHAVIORAL: Food reward after treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: To Demonstrate the Relative Bioequivalence of Lisinopril 1 x 40 mg Tablet Under Fasting and Fed
Status: COMPLETED
Conditions: Hypertension
Interventions: DRUG: Lisinopril 40 mg Tablet (Zestril) under fed conditions.|DRUG: Lisinopril 40 mg Tablet under fasting conditions.|DRUG: Lisinopril 40 mg Tablet under fed conditions.
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Welfare Benefits in Functional Somatic Disorders
Status: COMPLETED
Conditions: Fibromyalgia|Irritable Bowel Syndrome|Chronic Fatigue Syndrome|Bodily Distress Syndrome|Somatoform Disorders|Medically Unexplained Syndrome|Medically Unexplained Symptoms
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A
Status: COMPLETED
Conditions: Influenza A
Interventions: DRUG: ZSP1273 600 mg|DRUG: Placebo to Oseltamivir|DRUG: Oseltamivir(oral)|DRUG: Placebo to ZSP1273
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Given at 6, 7.5 and 9 Months of Age in Co-administration With Measles, Rubella and Yellow Fever (YF) Vaccines Followed by a Booster of the Malaria Vaccine.
Status: COMPLETED
Conditions: Malaria|Malaria Vaccines
Interventions: DIETARY_SUPPLEMENT: Vitamin A|BIOLOGICAL: Candidate Plasmodium falciparum malaria vaccine|BIOLOGICAL: MR-Vac|BIOLOGICAL: Stamaril
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Feasibility Study of PneumRx's Lung Volume Reduction Coil (LVRC)
Status: COMPLETED
Conditions: Emphysema
Interventions: DEVICE: Lung Volume Reduction Coil (LVRC) (PneumRx's)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Delayed Graft Function Using Paired Kidneys
Status: UNKNOWN
Conditions: Delayed Graft Function
Interventions: DRUG: BB3|DRUG: Normal Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: CYP3A4 Activity in Patients With Prostate Cancer Versus Male Patients With Other Solid Tumours
Status: COMPLETED
Conditions: Prostate Cancer|Solid Tumor, Adult
Interventions: DRUG: Midazolam
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Effect of Olorinab on Gastrointestinal Transit in Patients With Irritable Bowel Syndrome
Status: TERMINATED
Conditions: Irritable Bowel Syndrome
Interventions: DRUG: Olorinab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Copper Cu 64 PSMA I&T PET Imaging in Men With Suspected Recurrence of Prostate Cancer
Status: RECRUITING
Conditions: Prostate Cancer|Prostate Adenocarcinoma|Biochemical Recurrence of Malignant Neoplasm of Prostate
Interventions: DRUG: Copper Cu 64 PSMA I&T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does First Oral Intake After Emergence Predict the Incidence of Post-operative Vomiting in Children?
Status: COMPLETED
Conditions: Post-operative Vomiting
Interventions: OTHER: Apple Juice|OTHER: Water
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence
Status: COMPLETED
Conditions: Smoking Cessation|Tobacco Dependence
Interventions: DRUG: Varenicline|OTHER: Counseling and Support Materials|OTHER: Laboratory Assessments
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Docetaxel With or Without Metronomic Cyclophosphamide as First Line Chemotherapy in Metastatic Breast Cancer
Status: UNKNOWN
Conditions: Breast Cancer
Interventions: DRUG: Docetaxel and Cyclophosphamide (TC)|DRUG: Docetaxel (T)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of Umeclidinium Bromide/Vilanterol Compared With Fluticasone Propionate/Salmeterol Over 12 Weeks in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: DRUG: Umeclidinium bromide/Vilanterol|DRUG: Placebo ACCUHALER/DISKUS|DRUG: Fluticasone propionate/Salmeterol|DRUG: Placebo NDPI
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of a Transcranial Vibrating System for Minimizing Dizziness During Caloric Testing
Status: RECRUITING
Conditions: Vestibular Function Tests|Dizziness
Interventions: DEVICE: Efficacy of transcranial vibrating system on mitigating dizziness and nausea during caloric testing
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Surveillance and Follow-up for Latent Tuberculosis Infection and Risk of Developing Active Tuberculosis in Patients Receiving Long-term Dialysis
Status: COMPLETED
Conditions: To Predict the Potential of Development of Active Tuberculosis in Those Receiving Long-term Dialysis by Using Interferon-gamma Release Assy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of Plitidepsin in Combination With Sorafenib or Gemcitabine in Patients With Advanced Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Advanced Solid Tumors|Lymphomas
Interventions: DRUG: Plitidepsin and Sorafenib|DRUG: Gemcitabine and Plitidepsin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Racial Inequality in Inhaler Fills for COPD - A Trial of Reduced Cost-Sharing
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Proactive Outreach|OTHER: No Proactive Outreach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection
Status: COMPLETED
Conditions: Hepatitis B, Chronic
Interventions: DRUG: JNJ-73763989|BIOLOGICAL: JNJ-64300535|DRUG: ETV monohydrate|DRUG: Tenofovir disoproxil|DRUG: TAF
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparative Study Between Two Physiotherapy Protocols Conventional X Accelerated in Individuals Undergoing Reconstruction of the Anterior Cruciate Ligament.
Status: COMPLETED
Conditions: Rehabilitation|Anterior Cruciate Ligament Reconstruction|Knee
Interventions: OTHER: Nonaccelerated Rehabilitation|OTHER: Accelerated Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Status: ACTIVE_NOT_RECRUITING
Conditions: Neoplasms
Interventions: DRUG: Letetresgene autoleucel|DRUG: Cyclophosphamide|DRUG: Fludarabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Calcium and Magnesium Infusion for the Prevention of Taxane Induced Neuropathy
Status: COMPLETED
Conditions: Paclitaxel-induced Neuropathy
Interventions: DRUG: calcium gluconate and magnesium sulfate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study of GC022F CAR-T Cell Immunotherapy for Relapsed or Refractory B- ALL
Status: UNKNOWN
Conditions: B-cell Acute Lymphoblastic Leukemia
Interventions: BIOLOGICAL: GC022F
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied Drugs
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: ITCA 650 20/60 mcg/day|DRUG: Acetaminophen|DRUG: Atorvastatin|DRUG: Lisinopril|DRUG: Warfarin|DRUG: Digoxin
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
Status: UNKNOWN
Conditions: Bladder Cancer|Colorectal Cancer|Endometrial Cancer|Kidney Cancer|Skin Cancer|Uterus Cancer
Interventions: BEHAVIORAL: Health and Diet Questionnaire
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Assess the Safety, Tolerability and Immunogenicity of ASP3772, a Pneumococcal Vaccine, in Toddlers 12 to 15 Months of Age in Comparison to an Active Comparator
Status: COMPLETED
Conditions: Healthy Volunteers|Pneumococcal Disease
Interventions: BIOLOGICAL: ASP3772|BIOLOGICAL: PCV13
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: Immunogenicity and Safety of the Concomitant Administration of OVX836 and Quadrivalent Influenza Vaccine in Healthy Volunteers.
Status: COMPLETED
Conditions: Influenza
Interventions: BIOLOGICAL: OVX836 480µg|BIOLOGICAL: Quadrivalent Inactivated Influenza Vaccine (Fluarix® Tetra)|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Primary Care, Communication, and Improving Children's Health
Status: COMPLETED
Conditions: Childhood Obesity|Overweight|Communication|Weight Loss
Interventions: OTHER: Communication regarding overweight status|OTHER: Risk-factor assessment and counseling|OTHER: Lifestyle behavior assessment and counseling|OTHER: Interval follow-up to readdress weight|OTHER: Patient-centered communication
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Ispaghula and Colonic Water Content
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: 7 g Ispaghula|DIETARY_SUPPLEMENT: 7 g placebo|DIETARY_SUPPLEMENT: 3.5g Ispaghula + 3.5 g placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: HMP for Addictions Study
Status: NOT_YET_RECRUITING
Conditions: Opioid Use Disorder|Opioid Use|Buprenorphine Dependence
Interventions: BEHAVIORAL: Healthy Minds Program for Addictions
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction
Status: TERMINATED
Conditions: Cardiovascular Disease
Interventions: DRUG: Rosuvastatin|DRUG: Atorvastatin|RADIATION: Cardiac Computed Tomography (CT)|RADIATION: Cardiac Magnetic Resonance Image (MRI)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RCT of Fixed vs Titrated Letrozole in Breast Cancer Patient Undergoing IVF
Status: COMPLETED
Conditions: Breast Cancer|Infertility
Interventions: DRUG: Letrozole|DRUG: Letrozole
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Repeated Infusions of Mesenchymal Stromal Cells in Children With Osteogenesis Imperfecta
Status: COMPLETED
Conditions: Osteogenesis Imperfecta Type II|Osteogenesis Imperfecta Type III
Interventions: BIOLOGICAL: Mesenchymal Stromal Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: NSAIDs Stent Study
Status: RECRUITING
Conditions: Ureteral Stent Placement|Kidney Stone
Interventions: DRUG: Ketorolac Trometamol 30Mg/1mL Injection|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Randomized Phase II/Genomic Trial of Two Chemotherapy Regimens in Patients With Resected Pancreatic Adenocarcinoma
Status: COMPLETED
Conditions: Pancreatic Adenocarcinoma
Interventions: DRUG: Gemcitabine|DRUG: Abraxane|DRUG: FOLFIRINOX|RADIATION: Chemoradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy Evaluation of a Commercial Preparation Containing Lactobacillus Casei DG on the Reduction of the Painful Symptoms Related to the Irritable Bowel Syndrome (IBS). A Pilot Clinical Study
Status: COMPLETED
Conditions: Irritable Bowel Syndrome
Interventions: DIETARY_SUPPLEMENT: Lactobacillus casei DG
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT