pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Hereditary Non-polyposis Colon Cancer|Precancerous Condition
Interventions: OTHER: study of socioeconomic and demographic variables|PROCEDURE: evaluation of cancer risk factors|PROCEDURE: study of high risk factors
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention
Status: COMPLETED
Conditions: Smoking Cessation
Interventions: BEHAVIORAL: Group Cognitive Behavioral Therapy|BEHAVIORAL: General Health Education|DRUG: Transdermal Nicotine Patch
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of a Higher Dose of Ocrelizumab in Adults With Relapsing Multiple Sclerosis (RMS)
Status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Sclerosis
Interventions: DRUG: Ocrelizumab|DRUG: Ocrelizumab|DRUG: Antihistamine|DRUG: Methylprednisolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Low-intensity Exercise in Metabolic Syndrome
Status: COMPLETED
Conditions: Metabolic Syndrome|Obesity|Hypertension|Hyperlipidemias|Glucose Metabolism Disorders
Interventions: BEHAVIORAL: Low-intensity, general-fitness exercises|BEHAVIORAL: Psychoeducation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Hyperuricemia on Hypertension and Metabolic Syndrome
Status: COMPLETED
Conditions: Systolic and Diastolic Blood Pressure Levels|Uric Acid Levels|Metabolic Syndrome Parameters|Hepatic Enzymes
Interventions: DRUG: Allopurinol|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone Removal
Status: NOT_YET_RECRUITING
Conditions: Nephrolithiasis|Lithotripsy, Laser|Ureteroscopy
Interventions: PROCEDURE: Standard of Care Ureterorenoscopy|PROCEDURE: Standard of Care Ureterorenoscopy with MediNiK
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Improved Otologic Implants on Demand Intraoperatively With 3D CAD/CAM Autografts
Status: UNKNOWN
Conditions: Middle Ear Disease
Interventions: DEVICE: 3D CAD/CAM autograft prosthesis|DEVICE: Control device
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effective Study of ARNI on Ventricular Arrhythmia in HFrEF Patients With ICD or CRT-D (RHYTHM)
Status: TERMINATED
Conditions: Heart Failure
Interventions: DRUG: ACEI/ARB|DRUG: ARNI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
Status: COMPLETED
Conditions: Lymphatic Filariasis|Onchocerciasis|Soil Transmitted Helminth (STH) Infections
Interventions: DRUG: Annual versus Semiannual Albendazole plus Ivermectin Mass Drug Administration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study to Evaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: AP-101
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance
Status: COMPLETED
Conditions: Biomarkers, Pharmacological
Interventions: DRUG: Huperzine A|DRUG: Donepezil|DRUG: Galantamine|OTHER: Placebo
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety Study of CAT-8015 to Treat Advanced B-cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia (NHL or CLL)
Status: COMPLETED
Conditions: Non-Hodgkin Lymphoma|Chronic Lymphocytic Leukemia
Interventions: DRUG: CAT-8015 20 mcg/kg|DRUG: CAT-8015 30 mcg/kg|DRUG: CAT-8015 40 mcg/kg|DRUG: CAT-8015 50 mcg/kg|DRUG: CAT-8015 60 mcg/kg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis
Status: COMPLETED
Conditions: Rhinitis|Allergic|Perennial
Interventions: DRUG: levocetirizine dihydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Graded Exposure Therapy in Chronic Pelvic Pain
Status: UNKNOWN
Conditions: Chronic Pelvic Pain
Interventions: OTHER: Graded exposure therapy|OTHER: Physiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Benralizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis (EGPA) Study
Status: UNKNOWN
Conditions: Asthma
Interventions: DRUG: Benralizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficacy and Safety of A2 Milk on Digestion
Status: ACTIVE_NOT_RECRUITING
Conditions: Digestive Discomfort
Interventions: OTHER: A2 Milk|OTHER: A1/A2 Milk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Masitinib in Patients With Gastro-Intestinal Stromal Tumour Resistant to Imatinib
Status: COMPLETED
Conditions: Gastro Intestinal Stromal Tumor
Interventions: DRUG: masitinib|DRUG: sunitinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PEEZY Midstream Urine Device Compared to Catheterized Urine Sample
Status: COMPLETED
Conditions: Lower Urinary Tract Symptoms|Lower Urinary Tract Infection
Interventions: DEVICE: Midstream urine collection device|DEVICE: Catheter for urine collection
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Clinical Trial to Evaluate the Safety and Effects of Ethnicity and Food on Pharmacokinetics of YH25448
Status: COMPLETED
Conditions: Non-Small Cell Lung Cancer
Interventions: DRUG: YH25448 240mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers
Status: RECRUITING
Conditions: Healthy Volunteers Only
Interventions: DRUG: 83-0060|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NiPPV in the Treatment of Acute Asthma Exacerbations
Status: WITHDRAWN
Conditions: Bronchial Asthma|Status Asthmaticus
Interventions: PROCEDURE: Standard of Care therapies|DEVICE: NiPPV Therapy|PROCEDURE: Routine Respiratory Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Buprenorphine for Probationers and Parolees: Bridging the Gap Into Treatment
Status: RECRUITING
Conditions: Opioid Use
Interventions: DRUG: Buprenorphine/Naloxone|OTHER: Treatment as usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study)
Status: COMPLETED
Conditions: Heart Failure
Interventions: DRUG: LCZ696|DRUG: valsartan|DRUG: LCZ696 placebo|DRUG: valsartan placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Vitamin E Mixed Tocotrienols In Patients With Amyotrophic Lateral Sclerosis (ALS)
Status: UNKNOWN
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DIETARY_SUPPLEMENT: Tocotrienols|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism
Status: RECRUITING
Conditions: Type 2 Diabetes Mellitus|Hypogonadism
Interventions: DRUG: Testosterone gel 1.62%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation
Status: COMPLETED
Conditions: Functional Constipation
Interventions: DIETARY_SUPPLEMENT: Litesse powder containing 12 g polydextrose|DIETARY_SUPPLEMENT: Litesse powder containing 8 g polydextrose|DIETARY_SUPPLEMENT: Litesse powder containing 4 g polydextrose|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Study of CTS-1027 in Hepatitis C Patients
Status: COMPLETED
Conditions: Chronic Hepatitis C Virus Infection
Interventions: DRUG: CTS-1027|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study Evaluating AWBAT-D Versus the Standard of Care of Split-thickness Skin Graft Donor Sites
Status: WITHDRAWN
Conditions: Healing of Donor Site|Pain Level
Interventions: DEVICE: AWBAT-D
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Mini-sized MCE for Better Examination of UGI and Small Bowel
Status: COMPLETED
Conditions: Capsule Endoscopy
Interventions: DEVICE: mini-sized MCE|DEVICE: normal-sized MCE
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Papillomavirus Load in Rheumatic Inflammatory Diseases
Status: UNKNOWN
Conditions: Spondyloarthritis|Rhumatoid Arthisis
Interventions: DIAGNOSTIC_TEST: Cervical smear|DIAGNOSTIC_TEST: Pregnancy test|BEHAVIORAL: Sexual activity questionnary
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Evaluate the Safety and Efficacy of Botulax® as Compared to Botox® in Subject With Moderate to Severe Crow's Feet Lines
Status: COMPLETED
Conditions: Crow's Feet Lines
Interventions: DRUG: Botulinum toxin type A|DRUG: Botulinum toxin type A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Markers of Tissue Injury and Rhabdomyolysis in Patients With Major Trauma
Status: COMPLETED
Conditions: Tissue Injury|Major Trauma|Rhabdomyolysis
Interventions: DIAGNOSTIC_TEST: Laboratory analysis - upon admission|DIAGNOSTIC_TEST: Laboratory analysis - 24 hours after injury
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open-label Study Investigating the Disposition and QT/QTc Interval Effects of 400 mg [14C]-Iniparib(3.7 MBq, 100 µCi)
Status: COMPLETED
Conditions: Advanced Solid Tumors
Interventions: DRUG: Iniparib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effectiveness of Periodontitis Treatment on the Metabolic Activity of Symptomatic Carotid Atherosclerotic Plaque Responsible for Ischemic Stroke
Status: NOT_YET_RECRUITING
Conditions: Severe Periodontitis|Ischemic Stroke
Interventions: PROCEDURE: periodontal treatment strategy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Testing Immunosuppression Threshold in Renal Allografts To Extend eGFR
Status: COMPLETED
Conditions: Disorder Related to Renal Transplantation|Renal Transplant Rejection|Acute Graft Rejection
Interventions: OTHER: kSORT assay based follow-up|OTHER: Standard follow-up
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
Status: COMPLETED
Conditions: Traumatic Brain Injury|Subarachnoid Hemorrhage
Interventions: DRUG: Levetiracetam|DRUG: Phenytoin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pre- Versus Post-Incisional Pregabalin for Postoperative Pain Control
Status: UNKNOWN
Conditions: Postoperative Pain Control|Multimodal Analgesia
Interventions: DRUG: pregabalin|DRUG: epidural
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions
Status: COMPLETED
Conditions: Cognitive Change|Health Behavior|Health Literacy
Interventions: BEHAVIORAL: Cognitive Prescriptions
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: PT-112 in Subjects With Thymoma and Thymic Carcinoma
Status: RECRUITING
Conditions: Thymic Epithelial Tumor|Recurrent Thymoma|Thymic Cancer
Interventions: DRUG: PT-112
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of RC48-ADC(Antibody Drug Conjugate) and JS001 to Evaluate the Safety and Pharmacokinetics of Subjects With Locally Advanced or Metastatic Urothelial Cancer
Status: UNKNOWN
Conditions: Urothelial Carcinoma
Interventions: DRUG: RC48-ADC and JS001
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease
Status: NOT_YET_RECRUITING
Conditions: COPD|COPD Exacerbation
Interventions: COMBINATION_PRODUCT: Supported rescue pack
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Probiotics on Gingivitis
Status: COMPLETED
Conditions: Gingivitis; Chronic
Interventions: DIETARY_SUPPLEMENT: Dentoblis|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of the Use of a Therapeutic Conciliation Document at the Outlet of Hospital, on the Emergency Use of Hospital Care in Patient Aged Over 75 Years Old.
Status: WITHDRAWN
Conditions: Iatrogenic Effect
Interventions: OTHER: therapeutic drug conciliation sheet (TDC)|OTHER: No Use of therapeutic drug conciliation sheet (TDC)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Research Study Investigating Safety and Concentration in the Blood After One Dose Tablet of the New Medicine Monlunabant in Healthy Weight Japanese and Caucasian Men
Status: RECRUITING
Conditions: Obesity
Interventions: DRUG: Monlunabant|DRUG: Placebo (monlunabant)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TYRO Couples Project Study
Status: RECRUITING
Conditions: Couples
Interventions: OTHER: Intervention #1: Treatment Group Receiving On-Demand TYRO Services|OTHER: Intervention #2: Control Group Receiving In-Person TYRO Services
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Treatment for Subclinical AMR (Antibody-mediated Rejection) in Kidney Transplant Recipients
Status: TERMINATED
Conditions: Kidney Transplant Rejection
Interventions: DRUG: Tacrolimus Extended Release Oral Tablet [Envarsus]|OTHER: Plasma Exchange and IVIG (Intravenous Immunoglobulin )
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Validation of Structured Light Plethysmography
Status: COMPLETED
Conditions: Pulmonary Disease
Interventions: DEVICE: Structured Light Plethysmography|DEVICE: Pneumotachograph Spirometry
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Autologous BMMNCs Combined With Educational Intervention for ASD
Status: COMPLETED
Conditions: Autism Spectrum Disorder
Interventions: COMBINATION_PRODUCT: Autologous BMMNCs transplantation and educational intervention|COMBINATION_PRODUCT: Educational intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Superior and Inferior Capsulotomy in Bipolar Hemiarthroplasty Using Posterior Approach
Status: COMPLETED
Conditions: Femoral Neck Fractures
Interventions: PROCEDURE: inferior capsulotomy|PROCEDURE: superior capsulotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment
Status: ACTIVE_NOT_RECRUITING
Conditions: Amyotrophic Lateral Sclerosis
Interventions: OTHER: Placebo|DRUG: AMX0035
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Testing Afatinib as a Potential Targeted Treatment in Cancers With HER2 Genetic Changes (MATCH-Subprotocol B)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Lymphoma|Advanced Malignant Solid Neoplasm|Hematopoietic and Lymphoid Cell Neoplasm|Refractory Lymphoma|Refractory Malignant Solid Neoplasm|Refractory Multiple Myeloma
Interventions: DRUG: Afatinib Dimaleate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chewing Gum Facilitates an Earlier Return to Bowel Function in Pediatric Scoliosis Patients: A Prospective Randomized Study
Status: COMPLETED
Conditions: Scoliosis
Interventions: OTHER: Chewing gum|OTHER: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Weight Regain Post-RYGB: APC Versus APC Plus Endoscopic Suture Technique
Status: UNKNOWN
Conditions: Obesity
Interventions: PROCEDURE: APC|DEVICE: Endoscopic Suture Technique (OverStitch TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: To Investigate the Gingivitis Efficacy of a Stannous Fluoride Dentifrice in a Chinese Population
Status: COMPLETED
Conditions: Gingivitis
Interventions: OTHER: Stannous fluoride|OTHER: Sodium monofluorophosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Peri-implant Tissues in BLX® Implants
Status: COMPLETED
Conditions: Dental Implant Failed|Dental Prosthesis Failure
Interventions: PROCEDURE: Implant bed preparation protocol|PROCEDURE: Implant loading
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Use of Biotene Moisturizing Mouth Spray for Xerostomia Associated With Oral Oxybutynin Use
Status: WITHDRAWN
Conditions: Overactive Bladder|Xerostomia|Compliance
Interventions: DRUG: Biotene oral spray
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Clinical Carbetocin Myocardium Trial
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: Carbetocin|DRUG: Oxytocin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Blood Flow Restriction Resistance Exercises in COPDAE In-patient Rehabilitation
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease|Acute Exacerbation of COPD
Interventions: DEVICE: Blood flow restriction resistance exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Post-Stroke Enhancement of Delirium Outcomes With Reduction in Neuro-checks
Status: NOT_YET_RECRUITING
Conditions: Stroke, Acute|Stroke, Ischemic|Delirium|Neuro: Cerebrovascular Accident
Interventions: BEHAVIORAL: Decreased Neuro Checks overnight
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Nitrous Oxide for the Treatment of Major Depressive Disorder
Status: RECRUITING
Conditions: Depression|Major Depressive Disorder
Interventions: DRUG: Nitrous Oxide|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy
Status: RECRUITING
Conditions: Pain|Pain Syndrome|Pain, Chronic|Chronic Pain|Chronic Pain Syndrome|Neuropathic Pain|Peripheral Neuropathy|Peripheral Neuralgia|Peripheral Nerve Injury|Post Operative Pain|Post-Traumatic Neuralgia|Plexopathy
Interventions: DRUG: Adezunap (AP707)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC)
Status: UNKNOWN
Conditions: Pancreatic Ductal Adenocarcinoma|Metastatic Pancreatic Cancer|Circulating Tumor Cell
Interventions: OTHER: Detection of circulating tumor cells expressing Axl: CTC-AXL(+)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Treatment of Natural Killer/T Cell Lymphoma-I/II
Status: UNKNOWN
Conditions: Nasal and Nasal-type NK/T-cell Lymphoma
Interventions: OTHER: DDGP(cisplatin,dexamethasone,gemcitabine,pegaspargase)|OTHER: VIPD（cisplatin，Etoposide，Ifosfamide， dexamethasone，Mesna）|OTHER: gemcitabine,pegaspargase,cisplatin,dexamethasone|OTHER: cisplatin,Etoposide,Ifosfamide,dexamethasone,Mesna|RADIATION: Radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Status: RECRUITING
Conditions: Cardiometabolic Syndrome|Physical Inactivity|Hypertension|Type 2 Diabetes|PreDiabetes|Obesity|Cardiovascular Diseases|Smoking|Sleep|Hyperlipidemias|Diet, Healthy|Blood Pressure
Interventions: BEHAVIORAL: Black Impact Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Slow Chest Compression on Dynamic Hyperinflation, Dyspnea and Peripheral Muscle Deoxygenation in Patients With COPD
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: Slow chest compression|OTHER: No slow chest compression
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Effect of Dexamethasone Dose and Route on Duration of Interscalene Block After Outpatient Shoulder Surgery
Status: COMPLETED
Conditions: Pain, Postoperative|Disorder of Shoulder
Interventions: DRUG: Dexamethasone|DRUG: Bupivacaine|PROCEDURE: Interscalene brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ESD Versus EMR for Treatment of Early Barrett's Adenocarcinoma
Status: COMPLETED
Conditions: High Grade Intraepithelial Neoplasia|Barrett Adenocarcinoma
Interventions: PROCEDURE: Endoscopic mucosal resection|PROCEDURE: Waterjet-assisted ESD|DEVICE: HybridKnife
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Safety, Pharmacokinetics, and Activity of XmAb24306 in Combination With Cevostamab in Participants With Relapsed/Refractory Multiple Myeloma
Status: RECRUITING
Conditions: Multiple Myeloma
Interventions: DRUG: Cevostamab|DRUG: XmAb24306|DRUG: Tocilizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LEO 32731 for the Treatment of Moderate to Severe Psoriasis Vulgaris
Status: COMPLETED
Conditions: Psoriasis Vulgaris
Interventions: DRUG: LEO 32731|DRUG: LEO 32731 Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: IDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid Tumor
Status: RECRUITING
Conditions: Cholangiocarcinoma With IDH1 Mutation|Solid Tumors With IDH1 Mutation
Interventions: DRUG: AB-218 capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
Status: COMPLETED
Conditions: Chronic Troublesome Sialorrhea|Cerebral Palsy|Stroke|Traumatic Brain Injury|Intellectual Disability
Interventions: DRUG: NT 201 Placebo|DRUG: NT 201
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Effectiveness of Biofeedback for Individuals With Long-term Post-concussive Symptoms
Status: COMPLETED
Conditions: Post-Concussion Syndrome
Interventions: DEVICE: Heart Rate Variability Biofeedback|DEVICE: Neurofeedback
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcoma
Status: COMPLETED
Conditions: Sarcoma, Kaposi
Interventions: DRUG: Liposomal Doxorubicin|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Role of Low Lactose Infant Formula In The Management of Neonatal Abstinence Syndrome
Status: COMPLETED
Conditions: Neonatal Abstinence Syndrome
Interventions: OTHER: Low lactose or regular formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scars
Status: UNKNOWN
Conditions: Keloid
Interventions: DRUG: Topical Pirfenidone|DRUG: Triamcinolone + Pirfenidone|DRUG: Intralesional Triamcinolone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma
Status: COMPLETED
Conditions: Melanoma (Skin)
Interventions: BIOLOGICAL: aldesleukin|BIOLOGICAL: filgrastim|BIOLOGICAL: incomplete Freund's adjuvant|BIOLOGICAL: interleukin-2 gene|BIOLOGICAL: therapeutic tumor infiltrating lymphocytes|DRUG: cyclophosphamide|DRUG: fludarabine phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Zolpidem Tartrate Tablets Under Fasted Conditions
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Zolpidem Tartrate Tablets 10 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: |Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety of Rotarix™ in Chinese Children
Status: COMPLETED
Conditions: Infections, Rotavirus
Interventions: BIOLOGICAL: Rotarix ™|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Ho:YAG Laser Versus Thulium Laser for the Management of 2-4cm Kidney Stones During SMP
Status: NOT_YET_RECRUITING
Conditions: Kidney Stones
Interventions: PROCEDURE: Ho:YAG lasers|PROCEDURE: TFL
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrathecal Transplantation of UC-MSC in Patients With Sub-Acute Spinal Cord Injury
Status: UNKNOWN
Conditions: Spinal Cord Injury
Interventions: DRUG: Umbilical Cord Mesenchymal Stem Cells|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Single-arm Study to Evaluate the Safety and Efficacy of Pazopanib, in Subjects With FGFR2 Amplification, FGFR2 Mutation Refractory Solid Tumors
Status: COMPLETED
Conditions: Refractory Solid Tumors
Interventions: DRUG: pazopanib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetics Evaluation of Recombinant Coagulation Factor VIII Injection in Subjects With Hemophilia A.
Status: UNKNOWN
Conditions: Hemophilia A
Interventions: DRUG: Xyntha|DRUG: Recombinant Coagulation Factor VIII Injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Use of Fractional Exhaled Nitric Oxide in the Identification of Non-adherence in Difficult Asthma
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide (directly observed)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction
Status: COMPLETED
Conditions: Fetal Growth Retardation
Interventions: DRUG: Sildenafil citrate|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Effect of In-vitro Myoinositol Supplementation of Human Sperm on the Outcome of Cryopreservation
Status: COMPLETED
Conditions: Myoinositol|Cryopreservation|Human|Sperm
Interventions: BIOLOGICAL: Myoinositol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Uncomplicated Plasmodium Falciparum Malaria
Interventions: DRUG: Pyronaridine-Artesunate
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Endoscopic Ultrasound Guided Fine-needle Injection of Dendritic Cells Vaccination Into Unresectable Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: PROCEDURE: EUS-guided fine-needle injection of DCs vaccinations
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Drug-Drug Interaction Between Darunavir and Danoprevir Administered Together With Low-Dose Ritonavir in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteer
Interventions: DRUG: danoprevir|DRUG: darunavir|DRUG: ritonavir
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Effectiveness of Continence Promotion Interventions Among Community-dwelling Older Women
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: BEHAVIORAL: Constructivist interactive workshop on urinary incontinence|BEHAVIORAL: Evidence-based self-management tool|BEHAVIORAL: General health lecture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Trial of Alpha One Antitrypsin Inhalation in Treating Patient With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Status: UNKNOWN
Conditions: Coronavirus
Interventions: DRUG: alpha one antitrypsin inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pilot Study of the SPaRK (Supportive and Palliative Care Review Kit) Model of Care for Advanced Cancer Patients Who Have an Unplanned Admission to Singapore General Hospital
Status: COMPLETED
Conditions: Cancer
Interventions: OTHER: Integrated palliative oncology care
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer
Status: COMPLETED
Conditions: Kidney Cancer|Long-term Effects Secondary to Cancer Therapy in Adults|Perioperative/Postoperative Complications|Urinary Complications
Interventions: PROCEDURE: cold ischemia procedure|PROCEDURE: warm ischemia procedure
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Rasagiline in the Treatment of Persistent Negative Symptoms of Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia
Interventions: DRUG: rasagiline (Pharmacodynamics)|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: TheraSphere Selective Internal Radiation Therapy (SIRT) as Treatment for Neuroendocrine Tumours With Liver Mets
Status: RECRUITING
Conditions: Neuroendocrine Tumors|Liver Metastases
Interventions: RADIATION: TheraSpheres Selective Internal Radiation Therapy (SIRT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Upper Extremity Function, Shoulder Position Sense and Disability Level İn Patients With Multiple Sclerosis
Status: COMPLETED
Conditions: Physical Therapy|Upper Extremity Function|Position Sense
Interventions: OTHER: Upper extremity function|OTHER: Shoulder position sense
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: iCanWork: A Randomized Controlled Trial
Status: NOT_YET_RECRUITING
Conditions: Cancer-related Problem/Condition|Survivorship|Quality of Life
Interventions: BEHAVIORAL: iCanWork Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Trial to Investigate Intensified Neoadjuvant Chemotherapy in Locally Advanced Pancreatic Cancer
Status: COMPLETED
Conditions: Ductal Adenocarcinoma of the Pancreas
Interventions: DRUG: Gem/nab-Pac|DRUG: FOLFIFINOX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gyrate Atrophy Ocular and Systemic Study
Status: RECRUITING
Conditions: Gyrate Atrophy|Gyrata of Choroid and Retina; Atrophy|Ornithine-δ-aminotransferase|OAT|Chorioretinal Degeneration
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Guided Tissue Regeneration in the Healing of Through and Through Lesions
Status: UNKNOWN
Conditions: Periapical Lesions
Interventions: PROCEDURE: Resorbable membrane|PROCEDURE: periapical surgery without membrane
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy
Status: COMPLETED
Conditions: Tonsillitis|Pain
Interventions: DRUG: Codeine with acetaminophen|DRUG: Tramadol suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy and Safety of Topical Papaya (Carica Papaya) Leaf Extract 1% Ointment Versus Mupirocin 2% Ointment in the Treatment of Limited Impetigo: a Randomized, Double-blind, Controlled Clinical Trial
Status: UNKNOWN
Conditions: Impetigo
Interventions: DRUG: papaya 1% extract ointment|DRUG: mupirocin 2% ointment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Plantar Fascitiis: Comparison of ESWT and Collagen Hydrolyzed Peptides
Status: RECRUITING
Conditions: Plantar Fascitis
Interventions: DRUG: Collagen hydrolyzed peptides
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: e-Health Care Method for Patients With Osteogenesis Imperfecta (Tele OI)
Status: COMPLETED
Conditions: Osteogenesis Imperfecta
Interventions: OTHER: Tele OI
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
Status: COMPLETED
Conditions: Allergic Conjunctivitis
Interventions: DRUG: Reproxalap Ophthalmic Solution (0.25%)|DRUG: Vehicle Ophthalmic Solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Longitudinal Evaluation of Gastric Emptying and Accommodation in Children With Dyspepsia
Status: WITHDRAWN
Conditions: Gastroparesis|Dyspepsia
Interventions: OTHER: Gastric emptying breath test|OTHER: Stomach ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: An Open-Label Study of Once-Daily Oral Administration of Esomeprazole 40 mg in Patients With Symptoms of Gastroesophageal Reflux Disease (GERD)
Status: COMPLETED
Conditions: GERD
Interventions: DRUG: Esomeprazole
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Analgesic Efficacy of Liposomal Bupivacaine vs. Bupivacaine HCL as a Tap Block After Abdominally Based Autologous Breast Reconstruction
Status: TERMINATED
Conditions: Mammaplasty
Interventions: DRUG: Bupivicaine HCL|DRUG: Liposomal bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer Disease
Interventions: DRUG: LY3303560 - IV|DRUG: Placebo - IV|DRUG: Florbetapir F 18|DRUG: Flortaucipir F18
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure
Status: COMPLETED
Conditions: Anal Fissure
Interventions: PROCEDURE: Botox|DRUG: ISDN ointment|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients
Status: RECRUITING
Conditions: Heart Failure NYHA Class III|Heart Failure NYHA Class IV|Chronic Obstructive Pulmonary Disease Severe
Interventions: OTHER: ADLIFE intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Electro-acupuncture to Treat Disorder of Consciousness
Status: RECRUITING
Conditions: Disorder of Consciousness|Electroacupuncture
Interventions: OTHER: Electroacupuncture|OTHER: Sham electroacupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: ctDNA-guided Treatment of TKI Plus PD-1 Inhibitor for Advanced pMMR/MSS Colorectal Cancer
Status: RECRUITING
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Sintilimab|DRUG: Fruquintinib or Regorafenib|DRUG: Fruquintinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
Status: COMPLETED
Conditions: Mild Cognitive Impairment
Interventions: DRUG: Donepezil|DRUG: Atropine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Tranexamic Acid Reduce the Need for Blood Transfusions in Patients Undergoing Hip Fracture Surgery?
Status: COMPLETED
Conditions: Hip Fracture
Interventions: DRUG: tranexamic acid|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Influence of Microcurrent Parameters on Effectiveness in Treatment of Chronic Tennis Elbow
Status: COMPLETED
Conditions: Tennis Elbow
Interventions: PROCEDURE: Microcurrent treatment (controlled current)|PROCEDURE: Micocurrent treatment (controlled voltage)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mindful Waiting Room
Status: RECRUITING
Conditions: Anxiety State|Depressive State|Pain|Nausea|Fatigue|Cancer
Interventions: BEHAVIORAL: Body Scan|BEHAVIORAL: Mindful Breathing|BEHAVIORAL: Mindfulness of Discomfort|BEHAVIORAL: Mindful Savoring|BEHAVIORAL: Integrative Health Recording
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Drug Eluting Stent for the Management of PERipheral Arterial Disease Of the SFA (DESPERADO-SFA Study)
Status: COMPLETED
Conditions: Peripheral Arterial Disease
Interventions: DEVICE: Balloon Angioplasty|OTHER: Optical Coherence Tomography
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A follow-on Study to Assess Long-term Safety and Tolerability of i.c.v Administration of sNN0029 in Patients With ALS
Status: TERMINATED
Conditions: Amyotrophic Lateral Sclerosis
Interventions: DRUG: sNN0029 infusion solution
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial for Microarray Analysis of Colon Cancer Outcome-A (MACCO-A)
Status: TERMINATED
Conditions: Adenocarcinoma|Colon Cancer
Interventions: DRUG: XELOX|DRUG: XELIRI|DRUG: Bevacizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: LUX-Lung 5: Afatinib Plus Weekly Paclitaxel Versus Investigator's Choice of Single Agent Chemotherapy Following Afatinib Monotherapy in Non-small Cell Lung Cancer Patients Failing Erlotinib or Gefitinib
Status: COMPLETED
Conditions: Carcinoma, Non-Small-Cell Lung
Interventions: DRUG: Investigator´s choice of chemotherapy|DRUG: BIBW 2992
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT