pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary Disease
Status: RECRUITING
Conditions: Nontuberculous Mycobacterial Lung Disease|Mycobacterium Avium Complex
Interventions: DEVICE: Hypertonic Saline inhalation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of a Quality Improvement Toolkit in Kerala, India, Among Hospitals Treating Acute Coronary Syndrome Patients
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: BEHAVIORAL: Quality Improvement Toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Clarification of Optimal Anticoagulation Through Genetics
Status: COMPLETED
Conditions: Stroke|Venous Thrombosis|Atrial Fibrillation|Atrial Flutter
Interventions: BEHAVIORAL: Genotype-guided dosing algorithm for warfarin|BEHAVIORAL: Clinical-guided dosing algorithm for warfarin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Between Myopia Versus Hypermetropia With Progressive Addition Lenses in Computer Users
Status: ACTIVE_NOT_RECRUITING
Conditions: Myopia|Hypermetropia
Interventions: BEHAVIORAL: Myopia|OTHER: Hypermetropia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery
Status: COMPLETED
Conditions: Postoperative Complications
Interventions: PROCEDURE: Arrangement of small intestine order before close the abdomen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors
Status: RECRUITING
Conditions: Kidney Cancer
Interventions: PROCEDURE: Partial Nephrectomy (PN)|PROCEDURE: Radical Nephrectomy (RN)|PROCEDURE: Ablation therapy (AT)|DIAGNOSTIC_TEST: Active Surveillance (AS)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effect of Diet on Microbial Profile and Disease Outcomes in Patients With Inflammatory Bowel Diseases
Status: UNKNOWN
Conditions: Inflammatory Bowel Diseases|Crohn's Disease|Dietary Modification
Interventions: BEHAVIORAL: Mediterranean diet|BEHAVIORAL: Specific Carbohydrate Diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: A Single-Blind Placebo Run-in Study of Duloxetine for Activity-Limiting Osteoarthritis Pain
Status: COMPLETED
Conditions: Osteoarthritis|Pain
Interventions: DRUG: duloxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in Oman During COVID-19 Pandemic
Status: UNKNOWN
Conditions: Depressive Symptoms|Generalized Anxiety
Interventions: BEHAVIORAL: Therapist Guided E-Therapy|BEHAVIORAL: Self-Help Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial of an Herb and Mineral Combination Product on Fasting Glucose in Adults at Risk for Developing Diabetes
Status: COMPLETED
Conditions: Prediabetes
Interventions: DIETARY_SUPPLEMENT: herb and mineral combination product|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Assessment of Stainless Stain Crowns Placed Using the Hall Technique and Traditional Technique
Status: ENROLLING_BY_INVITATION
Conditions: Primary Teeth|Dental Caries|Dentin, Carious
Interventions: DEVICE: Hall technique|DEVICE: Traditional technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety Study of Cetuximab, Radiotherapy and Temozolomide in Primary Glioblastoma Multiforme(GERT)
Status: UNKNOWN
Conditions: Glioblastoma Multiforme
Interventions: DRUG: Cetuximab|DRUG: Temozolomide|PROCEDURE: Radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas
Status: COMPLETED
Conditions: Lymphoma|Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: L-778,123|DRUG: paclitaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Long-term Study in US Cystic Fibrosis Patients Receiving Digestive Enzyme Supplements to Assess Narrowing of the Large Intestine Causing Adverse Intestinal Symptoms (Fibrosing Colonopathy)
Status: TERMINATED
Conditions: Fibrosing Colonopathy
Interventions: BIOLOGICAL: ULTRESA|BIOLOGICAL: PANCREAZE|BIOLOGICAL: CREON|BIOLOGICAL: ZENPEP|BIOLOGICAL: other non-sponsor pancreatic enzyme replacement therapy|BIOLOGICAL: PERTZYE|OTHER: No pancreatic enzyme replacement therapy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study of IBI318 in Participants With Advanced Malignancies
Status: COMPLETED
Conditions: Advanced Malignancy
Interventions: BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318|BIOLOGICAL: IBI318
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Fractures Stratified by HIV and Antiretroviral Therapy (ART) Status
Status: COMPLETED
Conditions: Fracture|Infection, Human Immunodeficiency Virus
Interventions: OTHER: No Antiretroviral (ARV) Drug Exposure|DRUG: Any Antiretroviral (ARV) Drug Exposure
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A First-in-Human Study of EOS301984 as Monotherapy or Combination Therapy in Adult Participants With Advanced Solid Tumors
Status: RECRUITING
Conditions: Advanced Solid Tumors
Interventions: DRUG: EOS301984|DRUG: Anti-PD-1 monoclonal antibody
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia
Status: RECRUITING
Conditions: Hypoproteinemia|Pharmacokinetics|Ciprofol
Interventions: DRUG: ciprofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: CMRA for US-guided-MWA of Liver Tumors
Status: RECRUITING
Conditions: Regional Anesthesia|Pain Control|Microwave Ablation|Liver Tumors
Interventions: PROCEDURE: HHB+TAPB+and LA|PROCEDURE: HHB+LA|PROCEDURE: TAPB+LA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study of 64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors
Status: COMPLETED
Conditions: Malignant Solid Tumors
Interventions: DRUG: 2.5-3.5mCi 64Cu-FAPI-XT117|DRUG: 3.5-4.5mCi 64Cu-FAPI-XT117|DRUG: 4.5-5.5mCi 64Cu-FAPI-XT117
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Efficacy Study of an Unloading Brace for Knee Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis of the Knee
Interventions: DEVICE: Breg Fusion Unloading Brace
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: PREVENTION
Clinical trial: GBR With Ptfe With Bovine Bone With and Without Autogenous
Status: UNKNOWN
Conditions: Atrophied Anterior Maxillary Ridges
Interventions: OTHER: Geistlich Bio-Oss® bovine bone alone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Vestibular and Multisensory Influence on Bodily and Spatial Representations. Behavioral and Electrophysiological Investigations in Vestibular-defective Patients and Healthy Volunteers
Status: COMPLETED
Conditions: Vestibular-defective Patients
Interventions: OTHER: electromyography|OTHER: electroencephalography|OTHER: approaches from psychophysics
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Sumatriptan on the Postoperative Quality of Recovery After Elective Minimally Invasive Craniotomy
Status: COMPLETED
Conditions: Postoperative Quality of Recovery|Postoperative Migrainous Headache
Interventions: DRUG: Sumatriptan|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)
Status: COMPLETED
Conditions: Discoid Lupus Erythematosus
Interventions: DRUG: ASF 1096 0.5 % cream|DRUG: ASF 1096 placebo cream
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy
Status: ACTIVE_NOT_RECRUITING
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: DRUG: Nivolumab+Relatlimab|DRUG: Nivolumab+Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Avastin (Bevacizumab) in Combination With Low-Dose-Interferon in Patients With Metastatic Clear Cell Renal Cell Carcinoma (RCC).
Status: COMPLETED
Conditions: Renal Cell Cancer
Interventions: DRUG: bevacizumab [Avastin]|DRUG: interferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intra-dermal With Topical Imiquimod Pretreatment Versus Intra-muscular Hepatitis B Vaccination in IBD Patients
Status: COMPLETED
Conditions: Inflammatory Bowel Diseases|Hepatitis B
Interventions: BIOLOGICAL: Intradermal hepatitis B vaccine with imiquimod|BIOLOGICAL: Intramuscular hepatitis B vaccine with aqueous cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of 3 Novel Contact Lens Solutions on the Basal Lamina
Status: COMPLETED
Conditions: Contact Lens Solution
Interventions: DEVICE: Opti-Free contact lens solution|DEVICE: ReNu Multiplus contact lens solution|DEVICE: Clear Care contact lens solution
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bevacizumab + Triplet Treatment for Untreated With Chemotherapy Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: DRUG: Oxaliplatin (L-OHP)|DRUG: Irinotecan hydrochloride hydrate (CPT-11)|DRUG: Continuous intravenous infusion of fluorouracil (CIV 5-FU)|DRUG: Levofolinate calcium (l-LV)|DRUG: Bevacizumab (Bmab)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of the Protective Effect of Desflurane and Propofol in Patients With Renal Transplantation
Status: COMPLETED
Conditions: Healthy|End Stage Renal Disease
Interventions: DRUG: Desflurane|DRUG: Propofol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation in Individuals With COPD and Asymptomatic Individuals
Status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease
Interventions: OTHER: MMSE Test|OTHER: PASE Test|OTHER: The PRISMA-7 Frailty Scale|OTHER: TAMPA Test|OTHER: (JAMAR) Muscle Test|OTHER: Fatigue Severity Scale
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: APrevent Vocal Implant System (VOIS) for Adjustable Treatment of Unilateral Vocal Fold Paralysis (UVFP)
Status: COMPLETED
Conditions: Paralysis, Unilateral, Vocal Cord
Interventions: DEVICE: thyroplasty implant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DEVICE_FEASIBILITY
Clinical trial: Effects of Selexipag in Adults With Raynaud's Phenomenon Secondary to Systemic Sclerosis
Status: COMPLETED
Conditions: Raynaud's Phenomenon Secondary to Systemic Sclerosis
Interventions: DRUG: Selexipag|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Naltrexone Implants as an Aid in Preventing Relapse Following Inpatient Treatment for Opioid Addiction
Status: COMPLETED
Conditions: Opiate Dependence
Interventions: DRUG: Go Medical Naltrexone implants
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of Ambulatory Heart Rate Variability Biofeedback for Substance Use Disorder
Status: RECRUITING
Conditions: Substance Use Disorders
Interventions: DEVICE: Heart rate variability biofeedback + treatment as usual|BEHAVIORAL: Treatment as usual only
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer
Status: RECRUITING
Conditions: Colorectal Neoplasms|Chemotherapy Effect|Molecular Sequence Variation
Interventions: DRUG: Cetuximab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding
Status: COMPLETED
Conditions: Venous Thromboembolism|Menstruation
Interventions: DRUG: Apixaban|DRUG: Rivaroxaban
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Scapular Upward Rotation Focused Treatment for Patient With Shoulder Impingement Syndrome and a Positive Scapular Assistance Test
Status: UNKNOWN
Conditions: Subacromial Pain Syndrome|Impingement Syndrome|Scapular Dyskinesis
Interventions: OTHER: exercise|OTHER: manual therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Study Evaluating Safety and Efficacy of C-CAR011 Treatment in DLBCL Subjects
Status: COMPLETED
Conditions: Refractory Diffuse Large B-Cell Lymphoma
Interventions: BIOLOGICAL: C-CAR-011
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Antitumoral Activity and Safety of AEZS-108 in Women With LHRH Receptor Positive Gynecological Tumors
Status: COMPLETED
Conditions: Ovarian Cancer|Endometrial Cancer
Interventions: DRUG: AEZS-108
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Motivating Occupational Virtual Experiences In Therapy for Kids
Status: RECRUITING
Conditions: Virtual Reality|Occupational Therapy
Interventions: DEVICE: MOVE-IT Intervention|BEHAVIORAL: UCT Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of APX005M in Combination With Nivolumab and Ipilimumab in Treatment Naïve Patients With Advanced Melanoma or Renal Cell Carcinoma (RCC)
Status: ACTIVE_NOT_RECRUITING
Conditions: Advanced Melanoma|Renal Cell Carcinoma
Interventions: DRUG: Nivolumab|DRUG: Ipilimumab|DRUG: APX005M
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Assessment of the Effect of Vitamin D Supplementation on Inflammatory and Endothelial Factors in the Patients With Type 2 Diabetes .
Status: UNKNOWN
Conditions: Type2 Diabetes
Interventions: DIETARY_SUPPLEMENT: vitamin D|DIETARY_SUPPLEMENT: vitamin D placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Evaluation of Effectiveness of the Unplugged Program on Gambling Among Adolescents (GAPUnplugged)
Status: NOT_YET_RECRUITING
Conditions: Gambling
Interventions: BEHAVIORAL: Unplugged plus gambling component
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: The Effects and Safety of Low Calcium Dialysis on Coronary Artery Calcification in Maintenance Hemodialysis Patients
Status: UNKNOWN
Conditions: Coronary Artery Calcification
Interventions: OTHER: low calcium dialysis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Vaccine Therapy in Patients With Stage II, III, or IV Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer
Status: COMPLETED
Conditions: Fallopian Tube Cancer|Ovarian Cancer|Peritoneal Cavity Cancer
Interventions: BIOLOGICAL: rV-NY-ESO-1 vaccine|BIOLOGICAL: rF-NY-ESO-1 vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection
Status: TERMINATED
Conditions: Malaria
Interventions: DRUG: DSM265|DRUG: OZ439
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distal Targeter vs Free-hand
Status: COMPLETED
Conditions: Femur Fracture|Tibial Fractures|Nonunion of Fracture|Nonunion of Fracture of Tibia|Nonunion of Fracture of Femur (Diagnosis)|Tibia Fracture
Interventions: DEVICE: Distal targeting jig|PROCEDURE: Free-hand/perfect circles technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Monocular Action Video Game Treatment of Amblyopia
Status: COMPLETED
Conditions: Amblyopia|Amblyopia Occlusion|Unilateral Amblyopia|Anisometropic Amblyopia|Strabismic Amblyopia
Interventions: OTHER: Monocular Active Occlusion|OTHER: Monocular Passive Occlusion
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC).
Status: RECRUITING
Conditions: Squamous Cell Carcinoma|Urinary Tract Cancer
Interventions: DRUG: Atezolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.
Status: UNKNOWN
Conditions: Glaucoma, Open-Angle|Ocular Hypertension
Interventions: DRUG: Test - Bimatoprost 0.01% Ophthalmic Solution|DRUG: Reference - LUMIGAN® (Bimatoprost 0.01% Ophthalmic Solution)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Semaglutide Injection in the Treatment of Type 2 Diabetes Mellitus
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: BIOLOGICAL: semaglutide injection
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety Study of Mizoribine in Active Rheumatoid (AMOLED)
Status: UNKNOWN
Conditions: Rheumatoid Arthritis
Interventions: DRUG: Bredinin tablet 150mg|DRUG: Bredinin tablet 50mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: High Flow Nasal Cannula in Pediatric Patients After Cardiothoracic Surgery
Status: RECRUITING
Conditions: Pediatric Patients After Cardiothoracic Surgery
Interventions: DEVICE: high flow nasal cannula therapy|DEVICE: low flow nasal cannula therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Addressing Social Determinants of Health in Child Obesity Treatment Using Community Health Workers
Status: NOT_YET_RECRUITING
Conditions: Child Obesity|Social Determinants of Health
Interventions: OTHER: Community Health Worker|BEHAVIORAL: Child weight management intervention|OTHER: Standard of Care referral to resources
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma
Status: TERMINATED
Conditions: Glioblastoma|Glioblastoma Multiforme
Interventions: DRUG: Nivolumab|DRUG: Anti-GITR Monoclonal Antibody MK-4166|DRUG: IDO1 inhibitor INCB024360|DRUG: Ipilimumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa
Status: ACTIVE_NOT_RECRUITING
Conditions: Retinitis Pigmentosa
Interventions: BIOLOGICAL: CPK850
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Standing Trunk Extension and Spinal Height in Low Back Pain
Status: COMPLETED
Conditions: Low Back Pain
Interventions: OTHER: Repetitive Trunk Extension|OTHER: Sustained Trunk Extension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Hepalatide Combined With TAF and PEG-IFN as Finite Treatment of Chronic Hepatitis B Patients
Status: COMPLETED
Conditions: Chronic Hepatitis B
Interventions: DRUG: Hepalatide|DRUG: Placebo of Hepalatide|DRUG: Tenofovir Alafenamide Tablets|DRUG: Pegylated Interferon alfa 2a
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparative Study of Gene-activated Bone Substitute and Autobone in Treatment of Long Bone Nonunions
Status: UNKNOWN
Conditions: Non Union Fracture|Non-Union of Ankle Joint Without Infection
Interventions: COMBINATION_PRODUCT: "Histograft", a bone substitute based on octacalcium phosphate (OCP) and plasmid DNA encoding VEGFA gene
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Diffuse Gastric and Esophagogastric Junction Cancer S-1 Trial
Status: TERMINATED
Conditions: Metastatic Diffuse Gastric Cancer Including Carcinoma of the Gastro-esophageal Junction
Interventions: DRUG: S-1 (Tegafur+Gimeracil+Oteracil) /cisplatin (investigational arm)|DRUG: Fluorouracil/cisplatin (control arm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: State Anxiety Levels of Pregnant Women to Inform About Fetus With Ultrasound Images During Detailed Ultrasound.
Status: NOT_YET_RECRUITING
Conditions: Ultrasound|Perinatal Care|Anxiety
Interventions: OTHER: To inform
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Caffeine for Apnea of Prematurity-Sleep (CAP-S) Study
Status: COMPLETED
Conditions: Apnea of Prematurity
Interventions: DRUG: Caffeine citrate injection|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Indolent Systemic Mastocytosis With PA101
Status: COMPLETED
Conditions: Mastocytosis|Systemic Mastocytosis|Indolent Systemic Mastocytosis
Interventions: DRUG: PA101|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Radiation Therapy in Treating Women Who Have Undergone Surgery for Early-Stage Invasive Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: RADIATION: Standard Breast Irradiation|RADIATION: Breast Radiation plus Regional Radiation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Xanthohumol and Viral Infections (XL)
Status: RECRUITING
Conditions: Infection Viral
Interventions: DIETARY_SUPPLEMENT: Xanthohumol|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer
Status: COMPLETED
Conditions: Metastatic Colorectal Cancer
Interventions: OTHER: Best Supportive Care (BSC)|DRUG: Panitumumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Post Isometric Relaxation Technique & Eccentric Muscle Contraction on Hamstring Spasticity in CP
Status: COMPLETED
Conditions: Spastic Cerebral Palsy
Interventions: OTHER: Post isometric relaxation - Group I|OTHER: Eccentric Muscle contraction - Group II
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: An Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine
Status: COMPLETED
Conditions: Hand, Foot and Mouth Disease
Interventions: BIOLOGICAL: 400U /0.5ml EV71 vaccine|BIOLOGICAL: 0/0.5ml placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: A Study for Lymphocele and Lymphorrhea Control Following Inguinal and Axillary Radical Lymph Node Dissection
Status: COMPLETED
Conditions: Lymph Node Dissection|Lymphoedema|Lymphocoele
Interventions: DEVICE: Harmonic scalpel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Circulating Tumor DNA Guiding (Olaparib) Lynparza® Treatment in Ovarian Cancer
Status: UNKNOWN
Conditions: Ovarian Epithelial Cancer
Interventions: DRUG: Olaparib|DRUG: carboplatin + gemcitabine or carboplatin + paclitaxel or carboplatin + liposomal doxorubicin or liposomal doxorubicin 4-weekly or topotecan or paclitaxel weekly
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effectiveness of Endoscopic "Rendez-vous" Technique Foresophageal Reconstructions for the Treatment of a Total and Extensive Disruption of the Esophagus
Status: COMPLETED
Conditions: Esophageal Disruption|Esophageal Obstruction
Interventions: PROCEDURE: Recanalization
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC
Status: RECRUITING
Conditions: Head and Neck Squamous Cell Carcinoma
Interventions: DRUG: EBV-specific TCR-T cell with anti-PD1 auto-secreted element
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: HRT Versus MOS for Endometrial Preparation Prior to FET in Non PCOS Patients
Status: RECRUITING
Conditions: Infertility
Interventions: DRUG: Estradiol valerate|DRUG: Sequential Clomiphene citrate and Gonadotropin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Bioequivalence Study of Irinotecan Liposome Injection in Chinese Advanced Pancreatic Cancer.
Status: UNKNOWN
Conditions: Advanced Pancreatic Cancer
Interventions: DRUG: Irinotecan Liposome Injection combined with 5-FU/LV
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure Hydrocephalus
Status: COMPLETED
Conditions: Idiopathic Normal Pressure Hydrocephalus
Interventions: PROCEDURE: lowering of the performance level of an adjustable Strata valve in a ventriculoperitoneal (VP) shunt for treating idiopathic normal pressure hydrocephalus
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Clinical Utility of Endoscopic Closure Using a Dual Action Tissue (DAT) Clip
Status: RECRUITING
Conditions: GI Bleeding|Perforation Colon|Perforation Bowel|Perforation Duodenal|Perforated Bowel|Fistula
Interventions: DEVICE: DAT Clip
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: An Open Label Phase 4 Study to Evaluate Efficacy of Early Versus Late Use of Vedolizumab in Ulcerative Colitis
Status: COMPLETED
Conditions: Colitis, Ulcerative
Interventions: DRUG: Vedolizumab 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intragastric Balloon in Obese Patients With Uncontrolled Asthma
Status: RECRUITING
Conditions: Obesity|Asthma
Interventions: DEVICE: Intragastric balloon device|PROCEDURE: Dietary|PROCEDURE: Exercise intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pilot Study Related to the Effect of Clopidogrel on Plasmatic Soluble CD40 Ligand During Systemic Lupus Erythematous
Status: COMPLETED
Conditions: Systemic Lupus Erythematous
Interventions: DRUG: Treatment by clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Telerehabilitation on the Performance of Post-stroke Patients' Daily Living Activities and Evaluation of Satisfaction in Post-stroke Patients in Vietnam
Status: RECRUITING
Conditions: Stroke|Telerehabilitation|Acute Stroke
Interventions: BEHAVIORAL: Telerehabilitation for stroke patient
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
Status: RECRUITING
Conditions: Pregnancy Preterm|Pregnancy Prom|PROM, Preterm (Pregnancy)|PROM (Pregnancy)|Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor|Premature Birth
Interventions: DRUG: Azithromycin Pill|DRUG: Amoxicillin Pill
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Sage Extracts on Cognitive Function During Aerobic Exercise
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: Sage extracts Cognivia|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Safety and Efficacy of Nitric Oxide Gel in Promoting Hair Growth in Male Human Subjects With Androgenetic Alopecia
Status: UNKNOWN
Conditions: Alopecia Androgenica
Interventions: OTHER: Nitric Oxide (NO) Gel|OTHER: Placebo gel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Effect of Different Rapid Maxillary Expansion Appliances on Airway by Acoustic Rhinometry
Status: COMPLETED
Conditions: Posterior Crossbite, Upper Airway
Interventions: PROCEDURE: Rapid Maxillary Expansion Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Trial to Assess Lacosamide as the First add-on Anti-epileptic Drug Treatment in Patients With Partial-onset Seizures
Status: COMPLETED
Conditions: Partial Epilepsies
Interventions: DRUG: Lacosamide
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Chiropractic Spinal Manipulative Therapy for Acute Neck Pain
Status: RECRUITING
Conditions: Acute Neck Pain
Interventions: OTHER: Chiropractic spinal manipulative therapy (CSMT)|OTHER: CSMT sham manipulation|DRUG: Ibuprofen|DRUG: Placebo medication
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine for Sedation in Severe Traumatic Brain Injury
Status: NOT_YET_RECRUITING
Conditions: Severe Traumatic Brain Injury|Intracranial Hypertension|Intracranial Hemorrhage, Hypertensive
Interventions: DRUG: Ketamine with propofol|OTHER: Standard of Care propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intestinal Function in Neonates With Complex Congenital Heart Disease
Status: COMPLETED
Conditions: Congenital Heart Defects|Growth Failure
Interventions: OTHER: Arm 1: NPO by mouth pre-operative|OTHER: Arm 2: Fresh Breast Milk pre-operative
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Somatosensory Dysfunction as the Underlying Mechanism of Upper Limbs Motor Blocks in People With Parkinson's Disease
Status: COMPLETED
Conditions: Parkinson's Disease|Somatosensory Disorders
Interventions: DEVICE: Mechanical stimulus (vibration) applied on the forearm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SCREENING
Clinical trial: The Effect of Exparel on Post Operative Pain and Narcotic Use After Colon Surgery
Status: COMPLETED
Conditions: Post-operative Pain|Colon Cancer|Diverticulitis
Interventions: DRUG: Bupivacaine|DRUG: Bupivacaine liposome suspension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
Status: COMPLETED
Conditions: Mental Illness Persistent|Chronic Disease|Hypertension|Diabetes|Hypercholesterolemia|Depression|Obesity
Interventions: BEHAVIORAL: Reverse Colocated Integrated Care|BEHAVIORAL: Usual Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mobile Mindfulness Meditation Intervention to Improve the Well-Being of Cancer Survivors
Status: COMPLETED
Conditions: Cancer, Other Than Non-melanoma Skin Cancer
Interventions: BEHAVIORAL: Mobile Mindfulness Meditation|BEHAVIORAL: Mindfulness Coach
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Brock String Therapy Post Concussion
Status: RECRUITING
Conditions: Concussion, Brain|Near Point Convergence
Interventions: BEHAVIORAL: Brock String Therapy|BEHAVIORAL: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Chitosan Nano-hydroxyapatite Hydrogel in Non-Surgical Treatment of Intrabony Defect
Status: COMPLETED
Conditions: Chitosan|Nano-hydroxyapatite Hydrogel|Intrabony Defect
Interventions: OTHER: Nano-HAP/Chitosan hydrogel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Intravenous Bolus-infusion Versus Sliding Scale of Insulin for Intra-operative Glycemic Control
Status: COMPLETED
Conditions: Intraoperative Complications
Interventions: DRUG: Rapid-Acting Insulin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of Voluntary Neck Extension on Cerebral Blood Flow, in Breath-hold Divers Ending an Apnoea of Two Minutes or More.
Status: COMPLETED
Conditions: Healthy Amateur Divers
Interventions: OTHER: apnea performing
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Status: UNKNOWN
Conditions: Infertility|Assisted Reproductive Technology|IVF
Interventions: PROCEDURE: Afterload Transfer|PROCEDURE: Trial followed by transfer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of an Innovative BIO Formula Intake on Infant Growth and Tolerance From 0 to 6 Months
Status: COMPLETED
Conditions: Child Development
Interventions: OTHER: Breastfeeding|OTHER: Conventional BIO Infant formula|OTHER: TrueGreen BIO infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: Safety and Effectiveness of GP0112 for Cheek Augmentation and Correction
Status: WITHDRAWN
Conditions: Cheek Wrinkles|Midface Contour Deficiencies
Interventions: DEVICE: GP0112|DEVICE: Restylane Lyft Lidocaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Diluted Indocyanine Green Angiography: a Novel Approach to Free Flap Perfusion Evaluation in Reconstructive Microsurgery
Status: COMPLETED
Conditions: Free Flap Evaluation|Indocyanine Green Concentration|Perfusion
Interventions: DIAGNOSTIC_TEST: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer
Status: NOT_YET_RECRUITING
Conditions: Metastatic Colon Cancer
Interventions: DRUG: treatment adaptation guided by ctDNA variation|DRUG: standard management
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
Status: RECRUITING
Conditions: Alzheimer's Disease|Lewy Body Dementia|Parkinson's Disease
Interventions: RADIATION: DaTscan|RADIATION: F18-AV-45|RADIATION: FDG-PET|GENETIC: APOE genotype|PROCEDURE: Polysomnogram|BEHAVIORAL: Clinical Assessment
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Cleansing Efficacy of Waist-shaped Interdental Brushes.
Status: COMPLETED
Conditions: Periodontitis, Adult
Interventions: DEVICE: waist-shaped interdental brush|DEVICE: cylindric interdental brush
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: An Efficacy and Safety Study of Epoetin Alfa for Initiation and Maintenance Treatment of Patients With Anemia Associated With Chronic Kidney Disease
Status: COMPLETED
Conditions: Anemia
Interventions: DRUG: Epoetin alfa 3 times weekly /once weekly|DRUG: Epoetin alfa once weekly|DRUG: Epoetin alfa once every two weeks
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trial With Allergic Rhinitis Patients Taking GSK256066 Versus Placebo In A Pollen Challenge Chamber
Status: COMPLETED
Conditions: Rhinitis, Allergic, Seasonal|Seasonal Allergic Rhinitis
Interventions: DRUG: GSK256066
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Algorithm Using a Rapid Diagnostic Test for the Management of Childhood Febrile Diseases.
Status: COMPLETED
Conditions: Antimicrobial Resistance
Interventions: DIAGNOSTIC_TEST: Two-step malaria RDT detecting PfHRP2/pLDH (SD Ag Bioline Malaria Ag P.f/Pan: Standard Diagnostics, Hagal-Dong, Korea)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?
Status: UNKNOWN
Conditions: Shoulder Pain
Interventions: DRUG: Meloxicam 15 mg|PROCEDURE: Preoperative Interscalene Nerve Block|PROCEDURE: arthroscopic labral repair
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures
Status: COMPLETED
Conditions: Blood Sugar; High|Blood Pressure|Dietary Habits
Interventions: OTHER: Regular sweetened commercial foods|OTHER: Allulose sweetened commercial foods|OTHER: Whole and minimally processed and sweetened foods
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Statin for Depression in Patients Undergoing Coronary Artery Bypass Graft
Status: UNKNOWN
Conditions: Coronary Heart Disease
Interventions: DRUG: Rosuvastatin|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Combined FDG-PET and 123I-Iodometomidate Imaging for Adrenal Neoplasia
Status: UNKNOWN
Conditions: Adrenal Gland Neoplasms
Interventions: OTHER: FDG positron emission tomography|OTHER: Iodometomidate imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Supportive and Supportive-Expressive Treatment for Depression
Status: UNKNOWN
Conditions: Major Depressive Disorder
Interventions: BEHAVIORAL: Supportive-Expressive Therapy|BEHAVIORAL: Supportive Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery
Status: TERMINATED
Conditions: Hypoxia
Interventions: DRUG: Vasoconstrictor Agents|OTHER: Head/neck repositioning|OTHER: Increase ETCO2|OTHER: IV fluid bolus|DRUG: Additional anesthesia|BIOLOGICAL: RBC transfusion|DRUG: Increase FiO2
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: Behavioral Interventions to Prevent or Delay Dementia
Status: COMPLETED
Conditions: Mild Cognitive Impairment|Memory Disorders|Mild Dementia|Impaired Cognition|Mild Cognitive Disorder|Amnestic Disorder|Dementia and Amnestic Conditions|Poor Short-term Memory|Memory Impairment
Interventions: BEHAVIORAL: Cognitive Rehabilitation|BEHAVIORAL: Computer Brain Fitness Training|BEHAVIORAL: Support Group (patient and partner)|BEHAVIORAL: Wellness Education|BEHAVIORAL: Physical Exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Improving Effective Contraceptive Use Among Opioid-maintained Women: Stage II
Status: COMPLETED
Conditions: Contraceptive Usage|Opioid Dependence
Interventions: BEHAVIORAL: Treatment as usual|BEHAVIORAL: WHO contraception protocol|BEHAVIORAL: Incentives
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma
Status: COMPLETED
Conditions: Thyroid Cancer|Papillary Thyroid Microcarcinoma
Interventions: PROCEDURE: Thermal ablation|PROCEDURE: Thyroid lobectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p