pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects
Status: COMPLETED
Conditions: Infections, Bacterial
Interventions: DRUG: GSK2251052|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study of 141W94 Used Alone or in Combination With Zidovudine Plus 3TC in HIV-Infected Patients
Status: COMPLETED
Conditions: HIV Infections
Interventions: DRUG: Amprenavir|DRUG: Lamivudine|DRUG: Zidovudine
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Eltrombopag Olamine in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia
Status: TERMINATED
Conditions: Adult Acute Basophilic Leukemia|Adult Acute Eosinophilic Leukemia|Adult Acute Megakaryoblastic Leukemia (M7)|Adult Acute Minimally Differentiated Myeloid Leukemia (M0)|Adult Acute Monoblastic Leukemia (M5a)|Adult Acute Monocytic Leukemia (M5b)|Adult Acute Myeloblastic Leukemia With Maturation (M2)|Adult Acute Myeloblastic Leukemia Without Maturation (M1)|Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities|Adult Acute Myeloid Leukemia With Del(5q)|Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)|Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)|Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)|Adult Acute Myelomonocytic Leukemia (M4)|Adult Erythroleukemia (M6a)|Adult Pure Erythroid Leukemia (M6b)|Recurrent Adult Acute Myeloid Leukemia
Interventions: DRUG: eltrombopag olamine|PROCEDURE: standard follow-up care
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Jinshuibao Capsule on Diabetic Kidney Disease
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus|Diabetic Kidney Disease
Interventions: DRUG: Jinshuibao Capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Examining the Effectiveness of the Early Start Denver Model in Community Programs Serving Young Autism
Status: RECRUITING
Conditions: Autism
Interventions: BEHAVIORAL: Early Start Denver Model (ESDM)|BEHAVIORAL: Early Intensive Behavioral Intervention (EIBI)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Proactive and Reactive Balance Training Effects on Balance and Functional Performance Among Chronic Stroke Survivors
Status: ENROLLING_BY_INVITATION
Conditions: Stroke|Chronic Stroke|Balance
Interventions: OTHER: proactive balance training|OTHER: Reactive balance training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pentostatin and Alemtuzumab as a Preparative Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation
Status: TERMINATED
Conditions: Leukemia|Lymphoma|Hodgkin's Disease|Hematologic Neoplasms|Multiple Myeloma|Carcinoma, Renal Cell
Interventions: DRUG: Pentostatin|BIOLOGICAL: Alemtuzumab|PROCEDURE: Allogeneic hematopoietic stem cell transplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
Status: RECRUITING
Conditions: Renal Angiomyolipoma
Interventions: DRUG: Everolimus
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Testing the Effectiveness and Safety of a Passive Industrial Exoskeleton for the Upper Limb
Status: COMPLETED
Conditions: Prevention of Diseases of the Musculoskeletal System
Interventions: DEVICE: Passive industrial exoskeleton for the upper limb|OTHER: The protocol will be performed without exoskeleton
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Lenient Rate Control Versus Strict Rate Control for Atrial Fibrillation. The Danish Atrial Fibrillation Randomised Clinical Trial
Status: RECRUITING
Conditions: Atrial Fibrillation, Persistent|Atrial Fibrillation Chronic|Atrial Fibrillation
Interventions: OTHER: Rate control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Telehealth Pulmonary Rehabilitation for Hispanic and African-American Patients Admitted With Exacerbation of COPD
Status: COMPLETED
Conditions: COPD Exacerbation
Interventions: OTHER: Telehealth Pulmonary Rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Efficacy of Parenteral Iron Supplementation After Gastrointestinal Bleeding in Subjects Over 65
Status: COMPLETED
Conditions: Gastrointestinal Hemorrhage|Anemia
Interventions: DRUG: Ferinject 1000 mg|DRUG: Sodium chlorure 0,9 %
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: MS Fatigue and tDCS on Fatigue in Multiple Sclerosis
Status: UNKNOWN
Conditions: Fatigue in Multiple Sclerosis
Interventions: PROCEDURE: Real left prefrontal tDCS - sham|PROCEDURE: Sham - Real left prefrontal tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Stem Cells vs. Steroids for Discogenic Back Pain
Status: SUSPENDED
Conditions: Chronic Low Back Pain|Degenerative Disc Disease
Interventions: OTHER: Autologous stem cells|DRUG: Corticosteroid|DRUG: Local anesthetic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV
Status: COMPLETED
Conditions: HIV-1-infection
Interventions: DRUG: CVC 150 mg|DRUG: CVC 300 mg|OTHER: Placebo for CVC 150 mg|OTHER: Placebo for CVC 300 mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Near-Infrared Imaging of Peritoneal Carcinomatosis From Colorectal Cancer
Status: COMPLETED
Conditions: Colorectal Cancer|Peritoneal Carcinomatosis
Interventions: DRUG: Indocyanine Green
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Examining the Effect of EEG-guided Theta Burst Stimulation in Bipolar Disorder
Status: COMPLETED
Conditions: Bipolar Disorder
Interventions: DEVICE: Continuous Theta Burst Stimulation (cTBS)|DEVICE: Intermittent Theta Burst Stimulation (iTBS)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Evaluation of Influence of Two Treatment Protocols on Mandibular Movements and Condyle-fossa Relation
Status: UNKNOWN
Conditions: Temporomandibular Disorders
Interventions: PROCEDURE: interocclusal appliance|PROCEDURE: Relining of the complete dentures|PROCEDURE: Complete denture rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Impact of Diffuse Myocardial Fibrosis on the Ventricular Function in Regurgitant Left-Sided Valve Heart Diseases ( The DIFFUsE Study)
Status: UNKNOWN
Conditions: Valve Heart Diseases
Interventions: DEVICE: Cardiac MRI|BIOLOGICAL: blood samples|PROCEDURE: myocardial biopsy|GENETIC: blood samples
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE)
Status: COMPLETED
Conditions: Dry Eye
Interventions: DRUG: Lifitegrast|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid Malignancies
Status: COMPLETED
Conditions: Advanced Solid Malignancies|Non-Small Cell Lung Cancer (NSCLC)|Metastatic Castrate-Resistant Prostate Carcinoma (mCRPC)|Colorectal Carcinoma (CRC)
Interventions: DRUG: AZD4635|DRUG: Durvalumab|DRUG: Abiraterone Acetate|DRUG: Enzalutamide|DRUG: Oleclumab|DRUG: Docetaxel
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Point of Care Device Use in the Pediatric Emergency Department
Status: COMPLETED
Conditions: Dehydration|Seizure|Gastroenteritis|Hyperglycemia
Interventions: DEVICE: Point of Care Device; i-Stat Analyzer
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Treatment of Palmoplantar Psoriasis With Low Doses Interferential Current
Status: COMPLETED
Conditions: Psoriasis Palm & Soles
Interventions: DEVICE: PSORIAMED|DEVICE: PLACEBO
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Gycabiane and Glycemic Control of Prediabetic Subjects
Status: COMPLETED
Conditions: Hyperglycemia
Interventions: DIETARY_SUPPLEMENT: Glycabiane|DIETARY_SUPPLEMENT: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Alleviation of Alopecia in Breast Cancer Patient Using Synbiotics Formula
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer|Hair Loss
Interventions: DIETARY_SUPPLEMENT: BLHK03|DIETARY_SUPPLEMENT: Active placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Extracorporeal Focused Shock Wave Therapy for Primary Knee Osteoarthritis
Status: UNKNOWN
Conditions: Unilateral Primary Osteoarthritis of Knee
Interventions: DEVICE: Extracorporeal Shock Waves|DEVICE: Sham Extracorporeal Shock Waves|OTHER: Physical activities
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy & Safety of Symbicort® TURBUHALER® 160/4.5 µg Twice Daily & Pulmicort® TURBUHALER® 200 µg Twice Daily + Theolong® Tablet 200 mg Twice Daily in Japanese Asthmatic Patients
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: Budesonide/Formoterol|DRUG: Budesonide|DRUG: Theophylline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: An Exploratory Study Investigating Adhesive Reaction to Output
Status: COMPLETED
Conditions: Ileostomy
Interventions: OTHER: Patch 1|OTHER: Patch 2|OTHER: Patch 3|OTHER: Patch 4|OTHER: patch 5|OTHER: Patch 6
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Effect of Noninvasive Neuromodulation on Chronic Pain
Status: UNKNOWN
Conditions: Temporomandibular Dysfunction (TMD)
Interventions: DEVICE: active tDCS|DEVICE: active tDCS|DEVICE: sham tDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparative Study of Electric Toothbrushes for the Efficacy Plaque Removal and the Effect on Plaque Accumulation and Gingivitis.
Status: COMPLETED
Conditions: Dental Plaque Induced Gingivitis|Dental Plaque
Interventions: DEVICE: Oral B Healthy Clean Manual Toothbrush|DEVICE: BURST Sonic Oral Care|DEVICE: Philipps Sonicare DiamondClean 300 Series
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Telerehabilitation in People With Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson's Disease
Interventions: DEVICE: VRRS Tablet (Khymeia s.r.l., Noventa Padovana, Italy)|OTHER: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study in Patients With Moderate to Severe ARDS Due to COVID-19
Status: UNKNOWN
Conditions: Covid19
Interventions: BIOLOGICAL: hMSC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer
Status: NOT_YET_RECRUITING
Conditions: Hormone Receptor Positive HER-2 Negative Breast Cancer|Metastatic Breast Cancer|Recurrent Breast Cancer
Interventions: DRUG: Alisertib|DRUG: Endocrine therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cross-over Study to Prove Bioequivalence Between Two Oral Formulations of Levonorgestrel
Status: COMPLETED
Conditions: Contraception|Contraception, Postcoital
Interventions: DRUG: Levonorgestrel Emergency Pill (BAY86-5028/Opxion)|DRUG: Levonorgestrel (Postday)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose:
Clinical trial: Piloting "Signs of Safety": A Deaf-Accessible Therapy Toolkit for Alcohol Use Disorder and Trauma
Status: COMPLETED
Conditions: Alcohol Use Disorder|Post Traumatic Stress Disorder
Interventions: BEHAVIORAL: Seeking Safety + Signs of Safety toolkit
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Emergency Management of Spontaneous Intracerebral Haemorrhage - Biomarkers
Status: COMPLETED
Conditions: Cerebral Hemorrhage
Interventions: OTHER: Point-of-care bio-markers (cTnI, hsCRP, D-Dimer) and biological parameters (CBC, glucose, cholesterol, LDL cholesterol, triglycerides, fibrinogen)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Effects of Robot-Assisted Combined Therapy in Upper Limb Rehabilitation in Stroke Patients
Status: UNKNOWN
Conditions: Cerebrovascular Accident
Interventions: BEHAVIORAL: RAT-NMES|BEHAVIORAL: RAT-MT|BEHAVIORAL: Mirror therapy|BEHAVIORAL: Unilateral RAT|BEHAVIORAL: Bilateral RAT|BEHAVIORAL: Conventional rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 25-G Vitrectomy With Ranibizumab or Triamcinolone Acetonide on PDR in China-Randomized Clinical Trial
Status: UNKNOWN
Conditions: Proliferative Diabetic Retinopathy
Interventions: DRUG: Ranibizumab|DRUG: Triamcinolone Acetonide
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Perioperative Intravenous Lidocaine in Liver Surgery
Status: RECRUITING
Conditions: Liver Metastases|Liver Cancer|Postoperative Pain|Opioid Use
Interventions: DRUG: Lidocaine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Peripheral Venous Cannulation in Patient Undergoing Elective Surgery Under General Anesthesia.
Status: COMPLETED
Conditions: Peripheral Vein Cannulation Guided by Ultrasound
Interventions: PROCEDURE: Peripheral vein cannulation|PROCEDURE: Cannulation without ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Filgrastim and Chemotherapy Followed by Peripheral Stem Cell Transplant in Treating Patients With Hodgkin's Lymphoma or Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: BIOLOGICAL: filgrastim|DRUG: carmustine|DRUG: cyclophosphamide|DRUG: cytarabine|DRUG: dexamethasone|DRUG: etoposide|DRUG: mitoxantrone hydrochloride|PROCEDURE: peripheral blood stem cell transplantation|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Activity of Valomaciclovir in Infectious Mononucleosis Due to Primary Epstein-Barr Virus Infection
Status: COMPLETED
Conditions: Infectious Mononucleosis
Interventions: DRUG: Valomaciclovir|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery
Status: TERMINATED
Conditions: Respiratory Failure
Interventions: DEVICE: Neurally-Adusted Ventilatory Assist (NAVA)|DEVICE: Biphasic Positive Airway Pressure Support (BiPAP)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Microtransplantation With Decitabine and Cytarabine Improves Patient Outcomes in Myelodysplastic Syndromes
Status: COMPLETED
Conditions: Myelodysplastic Syndromes
Interventions: BIOLOGICAL: Microtransplantation
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Transitioning to a Valve -Gated Intrathecal Drug Delivery System
Status: UNKNOWN
Conditions: Pain|Pain, Chronic|Pain, Intractable|Pain, Back
Interventions: DEVICE: Prometra II Programmable Pump system - Flowonix Medical
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Autologous Cultured Adipose -Derived Stem Cells for the Crohn's Fistula
Status: COMPLETED
Conditions: Crohn's Fistula
Interventions: DRUG: ADIPOPLUS
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Nano-PSO in Parkinson's Disease.
Status: UNKNOWN
Conditions: Parkinson Disease
Interventions: DIETARY_SUPPLEMENT: nano-PSO|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Pentaerithrityl Tetranitrate (PETN) for Secondary Prevention of Intrauterine Growth Restriction
Status: UNKNOWN
Conditions: Fetal Growth Retardation|Pregnancy Related|Intrauterine Growth Restriction
Interventions: DRUG: Pentalong|DRUG: Placebos
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: An Immunologic Study of Treatment-Naive HIV Patients Starting a Darunavir/Ritonavir- or Efavirenz-Based HAART
Status: COMPLETED
Conditions: Human Immunodeficiency Virus; HIV
Interventions: DRUG: Darunavir/Ritonavir (DRV/r)|DRUG: Efavirenz (EFV)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: XRP9881 in Combination With Trastuzumab in Metastatic Breast Cancer
Status: COMPLETED
Conditions: Breast Neoplasms
Interventions: DRUG: larotaxel (XRP9881)|DRUG: trastuzumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effect of Pork With Modified Fat Composition and Berries on Plasma Fatty Acids and Fecal Compounds in Healthy Adults
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: DIETARY_SUPPLEMENT: Modified pork|DIETARY_SUPPLEMENT: Pork|DIETARY_SUPPLEMENT: Pork and berries
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Venetoclax in Addition to Blinatumomab in Adult Patients With Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
Status: RECRUITING
Conditions: ALL, Recurrent, Adult
Interventions: DRUG: Blinatumomab|DRUG: Venetoclax
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention
Status: NOT_YET_RECRUITING
Conditions: Kidney Stone
Interventions: DRUG: Indapamide 2.5 MG|DRUG: Hydrochlorothiazide 50Mg|DRUG: Chlorthalidone 25mg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Mometasone Furoate Nasal Spray for Treatment of Nasal Polyposis After Surgery (Study P03218)
Status: COMPLETED
Conditions: Nasal Polyps
Interventions: DRUG: Mometasone Furoate Nasal Spray|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: XPO-1 in Combination With RCHOP for DH/TH Lymphoma
Status: RECRUITING
Conditions: Double Hit Lymphoma|Triple Hit Lymphoma
Interventions: DRUG: Selinexor+RCHOP
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia
Status: TERMINATED
Conditions: Acute Leukemias of Ambiguous Lineage|Acute Undifferentiated Leukemia|Angioimmunoblastic T-cell Lymphoma|Blastic Phase Chronic Myelogenous Leukemia|Childhood Burkitt Lymphoma|Childhood Chronic Myelogenous Leukemia|Childhood Diffuse Large Cell Lymphoma|Childhood Immunoblastic Large Cell Lymphoma|Childhood Nasal Type Extranodal NK/T-cell Lymphoma|Cutaneous B-cell Non-Hodgkin Lymphoma|Hepatosplenic T-cell Lymphoma|Intraocular Lymphoma|Noncutaneous Extranodal Lymphoma|Peripheral T-cell Lymphoma|Recurrent Childhood Acute Lymphoblastic Leukemia|Recurrent Childhood Acute Myeloid Leukemia|Recurrent Childhood Anaplastic Large Cell Lymphoma|Recurrent Childhood Grade III Lymphomatoid Granulomatosis|Recurrent Childhood Large Cell Lymphoma|Recurrent Childhood Lymphoblastic Lymphoma|Recurrent Childhood Small Noncleaved Cell Lymphoma|Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma|Recurrent Mycosis Fungoides/Sezary Syndrome|Recurrent/Refractory Childhood Hodgkin Lymphoma|Refractory Chronic Lymphocytic Leukemia|Refractory Hairy Cell Leukemia|Relapsing Chronic Myelogenous Leukemia|Small Intestine Lymphoma|Unspecified Childhood Solid Tumor, Protocol Specific
Interventions: DRUG: dexrazoxane hydrochloride|DRUG: doxorubicin hydrochloride|DRUG: obatoclax mesylate|DRUG: liposomal vincristine sulfate|OTHER: pharmacological study|OTHER: laboratory biomarker analysis
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients
Status: ACTIVE_NOT_RECRUITING
Conditions: Thyroid Cancer
Interventions: RADIATION: I131 1.1 GBq
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: GI-Reasons- A Trial Of GI Safety Of Celecoxib Compared With Non-Selective Nonsteroidal Antiinflammatory Drugs (NSAIDS)
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Celecoxib|DRUG: Any commercially available NSAID with the indication for osteoarthritis
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Continue vs. Stop P2Y12 Inhibitor on Bleeding in Patient Receiving DAPT Undergoing Dental Procedure.
Status: UNKNOWN
Conditions: Dental Diseases|Antiplatelet Agents|Antiplatelet Drugs
Interventions: DRUG: Clopidogrel
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Pre-Operative Chemoradiotherapy Using Capecitabine, Radiation & Cetuximab, in Rectal Cancer
Status: COMPLETED
Conditions: Colon Rectal Cancer Duke Stage Stageval
Interventions: DRUG: Capecitabine (Xelodaâ), XRT & Cetuximab (Erbitux®)
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Virtual Bronchoscopy (VB) vs. Endobronchial Ultrasound (EBUS) Guided Mediastinal Sampling
Status: UNKNOWN
Conditions: Lung Cancer,|Mediastinal Tumors,|Lymphomas,|Sarcoidosis,
Interventions: PROCEDURE: virtual bronchoscopy guided transbronchial needle aspiration|PROCEDURE: endobronchial ultrasound guided transbronchial needle aspiration
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: PPI-amoxicillin for H. Pylori Treatment
Status: UNKNOWN
Conditions: Helicobacter Pylori Infection
Interventions: DRUG: Rabeprazole|DRUG: Bismuth potassium citrate|DRUG: Metronidazole|DRUG: Amoxicillin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Physical Exercise and Mental Wellbeing Rehabilitation for Acute Stress-induced Takotsubo Cardiomyopathy: The PLEASE Study
Status: COMPLETED
Conditions: Takotsubo Cardiomyopathy
Interventions: OTHER: Physical Exercise Program|BEHAVIORAL: Cognitive Behavioural Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Comparison of Posterior Tibial Nerve Electrical Stimulation Protocols for Overactive Bladder Syndrome
Status: COMPLETED
Conditions: Overactive Bladder Syndrome
Interventions: DEVICE: TENS 1-1|DEVICE: TENS 1-2|DEVICE: TENS 2-1|DEVICE: TENS 2-2|DEVICE: TENS 0-1
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of IMSA101 in Refractory Malignancies
Status: COMPLETED
Conditions: Solid Tumor, Adult
Interventions: DRUG: IMSA101|DRUG: Immune checkpoint inhibitor (ICI)|DRUG: Immuno-oncology (IO) therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Gentulizumab in Patients With Advanced Solid Malignancies and Non-Hodgkin Lymphoma
Status: TERMINATED
Conditions: Solid Tumor|Non-Hodgkin Lymphoma
Interventions: DRUG: Gentulizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of AXT-1003 in Subjects With Advanced Malignant Tumors.
Status: NOT_YET_RECRUITING
Conditions: Non-Hodgkin Lymphoma|Advanced Solid Tumor
Interventions: DRUG: AXT-1003
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Probiotics as an Adjunct to Treatment of SIBO With Rifaximin
Status: RECRUITING
Conditions: Irritable Bowel Syndrome|Small Intestinal Bacterial Overgrowth|SIBO
Interventions: DRUG: Rifaximin 200 MG|DIETARY_SUPPLEMENT: Probiotic
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Lower Body Positive Pressure Treadmill Training in Post-Stroke Gait Impairment
Status: COMPLETED
Conditions: Gait, Hemiplegic
Interventions: DEVICE: AlterG Treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness of Dry Needling and STM on Pain Management for ACLR
Status: UNKNOWN
Conditions: Pain and Anterior Cruciate Ligament Reconstruction
Interventions: OTHER: Dry needling and STM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Topical Vancomycin in Prevention of Methicillin-Resistant Staphylococcal Related Mediastinitis in Patients Receiving Coronary Artery Bypass Graft
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: PROCEDURE: coronary artery bypass grafting via midline sternotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Study to Evaluate the Efficacy and Safety of Nintedanib (BIBF 1120) + Prednisone Taper in Patients With Radiation Pneumonitis
Status: COMPLETED
Conditions: Lung Cancer|Lung Metastases
Interventions: DRUG: Nintedanib|DRUG: Prednisone|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Single and Multiple Ascending Dose Trial of KT-474 in Healthy Adult Volunteers and Patients With Atopic Dermatitis (AD) or Hidradenitis Suppurativa (HS)
Status: COMPLETED
Conditions: Healthy Volunteer|Atopic Dermatitis|Hidradenitis Suppurativa
Interventions: DRUG: KT-474/Placebo|DRUG: KT-474
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: 12-month Study of AMG 073 in Renal Osteodystrophy
Status: COMPLETED
Conditions: Renal Osteodystrophy
Interventions: DRUG: AMG 073|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Status: COMPLETED
Conditions: Autism|Asperger's Syndrome|Generalized Anxiety Disorder|Social Phobia|Separation Anxiety Disorder|Obsessive-compulsive Disorder
Interventions: BEHAVIORAL: Cognitive-behavioral therapy|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Comparison of the Safety and Effectiveness of Two Forms of Patient-controlled Pain Medication Used After Total Hip Replacement: The E-TRANS Fentanyl Transdermal System Versus the Morphine Intravenous Pump
Status: COMPLETED
Conditions: Pain, Postoperative|Analgesia
Interventions: DRUG: E-TRANS Fentanyl hydrochloride; Morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intranasal Insulin in Parkinson's Disease
Status: RECRUITING
Conditions: Parkinson Disease
Interventions: DRUG: Regular Novolin R|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Multi-center Study of Myeloablative Allo Stem Cell Transplant for Non-remission AML Using CloBu4 Regimen
Status: COMPLETED
Conditions: Acute Myeloblastic Leukemia
Interventions: DRUG: Clofarabine/Busulfan x 4|PROCEDURE: Peripheral blood stem cell transplant
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Human Metabolic Dynamics at Rest and During Aerobic Exercise Under Normobaric Normoxic and Moderate Hypoxic Conditions
Status: COMPLETED
Conditions: Energy Metabolism|Hypoxia|Metabolism and Nutrition Disorder
Interventions: BEHAVIORAL: 30-minute movement activity|OTHER: Hypoxia
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Optimized Dual CD33/CLL1 CAR T Cells in Subjects With Refractory or Relapsed Acute Myeloid Leukemia
Status: UNKNOWN
Conditions: Acute Myeloid Leukemia
Interventions: BIOLOGICAL: Dual CD33/CLL1 CAR T
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of the Effects of Obesity Surgery on Appetitive Behaviour
Status: COMPLETED
Conditions: Roux-en-Y Bariatric Surgery
Interventions: DRUG: Octreotide|DRUG: Saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Gait Improvement After Increased Frequency of Robot-assisted Gait Training in Cerebral Palsy Children
Status: UNKNOWN
Conditions: Cerebral Palsy Spastic Diplegia
Interventions: OTHER: Robotic assisted gait training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Time to Eradication of Mycoplasma Genitalium and Chlamydia Trachomatis After Treatment Commenced
Status: UNKNOWN
Conditions: Urethritis|Cervicitis|Genital Mycoplasma Infection|Chlamydia Trachomatis
Interventions: DRUG: Azithromycin|DRUG: Doxycycline|DRUG: lymecycline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of Acupuncture on Postoperative Delirium in Patients With Diabetes Mellitus
Status: NOT_YET_RECRUITING
Conditions: Acupuncture|Postoperative Delirium (POD)|Diabetes Mellitus
Interventions: DEVICE: acupuncture|DEVICE: placebo acupuncture
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of Efficacy and Safety of Nilotinib in Combination With Chemotherapy in Elderly Patients With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: Philadelphia Chromsome Positive Acute Lymphoblastic Leukemia
Interventions: DRUG: Nilotinib
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mesalazine Effects in Sporadic Colorectal Adenoma Patients
Status: COMPLETED
Conditions: Sporadic Colorectal Adenoma
Interventions: DRUG: Mesalazine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: awake prone positioning with advanced respiratory support (high-flow nasal cannula or continuous positive airway pressure)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Nicotine Delivery From Novel Non-Tobacco Electronic System in Smokers
Status: COMPLETED
Conditions: Cigarette Smoker|Current Smoker|Healthy Subject
Interventions: OTHER: Electronic Cigarette|OTHER: Electronic Cigarette|OTHER: Laboratory Biomarker Analysis|OTHER: Pharmacological Study|OTHER: Questionnaire Administration
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Enhancing Motor Plasticity After Perinatal Stroke Using tDCS
Status: COMPLETED
Conditions: Perinatal Stroke|Cerebral Palsy
Interventions: DEVICE: Interventional TDCS|DEVICE: Sham TDCS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Mini Plates Anchorage With Forsus Fatigue Resistant Device
Status: COMPLETED
Conditions: Malocclusion, Angle Class II, Division 1
Interventions: DEVICE: FFRD and mini plates group|DEVICE: Conventional FFRD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Value of Gym-based Exercise Training for Young Adults Receiving Antipsychotic Medication: The Vega Trial
Status: RECRUITING
Conditions: Affective Disorder|Psychosis
Interventions: BEHAVIORAL: Supervised exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Strengthening Mental Abilities With Relational Training (SMART) in Multiple Sclerosis (MS): A Feasibility Trial
Status: RECRUITING
Conditions: Multiple Sclerosis
Interventions: BEHAVIORAL: SMART|BEHAVIORAL: Sham brain training (Sudoku)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Nonalcoholic Fatty Liver Disease and Atherosclerotic Risk in Children
Status: COMPLETED
Conditions: Overweight and Obesity|Non-alcoholic Fatty Liver Disease
Interventions: BEHAVIORAL: Exercise|BEHAVIORAL: After-school program
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Tislelizumab Plus TKI as Adjuvant Therapy Versus Active Surveillance in Patients With HCC
Status: RECRUITING
Conditions: Liver Neoplasms
Interventions: DRUG: Tislelizumab plus tyrosine kinase inhibitor
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pregnancy Rate by HCG Administration Versus Urinary LH Surge Method in Patients Undergoing IUI
Status: COMPLETED
Conditions: Pregnancy
Interventions: DRUG: LH|DRUG: HCG|DRUG: Clomiphene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Impact of Three Distinct Exercise Types on Fatigue, Anxiety, and Depression in Parkinson's Disease
Status: TERMINATED
Conditions: Parkinson's Disease
Interventions: BEHAVIORAL: Spinning Class|BEHAVIORAL: Yoga Class|BEHAVIORAL: Dance Class|OTHER: No Exercise Class
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mucociliary Clearance, Airway Inflammation and Nasal Symptoms in Urban Motorcycle-drivers
Status: COMPLETED
Conditions: Attitude to Health
Interventions: OTHER: saline and sniffing|OTHER: sniffing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: UCSF College Health Study on Contraceptive Training and Education at Community Colleges
Status: ACTIVE_NOT_RECRUITING
Conditions: Contraception
Interventions: BEHAVIORAL: Contraceptive Training and Education|BEHAVIORAL: Placebo Nutrition Education
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Phase 2 Study of Imprime PGG & Pembrolizumab in Subjects With Adv SCCHN Who Failed Pembro Monotherapy or Experiencing SD
Status: TERMINATED
Conditions: Squamous Cell Carcinoma of the Head and Neck
Interventions: BIOLOGICAL: Imprime PGG|DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tralokinumab Monotherapy for Moderate to Severe Atopic Dermatitis - ECZTRA 2 (ECZema TRAlokinumab Trial no. 2)
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Tralokinumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
Status: RECRUITING
Conditions: Neuropathy Ulnar
Interventions: PROCEDURE: Simple decompression|PROCEDURE: Subcutaneous anterior transposition
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy and Safety of Rivastigmine Transdermal Patch in Patients With Mild to Moderate Alzheimer's Disease
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rivastigmine transdermal patch|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities
Status: COMPLETED
Conditions: Actinic Keratosis
Interventions: DRUG: Aminolevulinic Acid (ALA)|DRUG: Topical Solution Vehicle|DEVICE: Blue Light Photodynamic Therapy Illuminator (BLU-U)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Semaglutide, and Cilofexor/Firsocostat, Alone and in Combination, in Adults With Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)
Status: ACTIVE_NOT_RECRUITING
Conditions: Nonalcoholic Steatohepatitis
Interventions: DRUG: Semaglutide (SEMA)|DRUG: Cilofexor (CILO)/Firsocostat (FIR)|DRUG: PTM SEMA|DRUG: PTM CILO/FIR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of the Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit Gene
Status: COMPLETED
Conditions: Unresectable or Metastatic Malignant Gastrointestinal Stromal Tumor (GIST)
Interventions: DRUG: Imatinib mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Efficacy of Character Strengths Intervention in Enhancing Character Strengths and Self-esteem Among Adolescents
Status: COMPLETED
Conditions: Mental Health Issue|Mutism|Orthopedic Disorder
Interventions: BEHAVIORAL: Character Strengths Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: TPF Followed by Cetuximab and IMRT Plus Carbon Ion Boost for Locally Advanced Head and Neck Tumors
Status: TERMINATED
Conditions: Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN): Oro-, Hypopharyngeal and Laryngeal Cancer
Interventions: RADIATION: carbon ion boost
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Does Wearing Hearing Aids Impact the Affective State of Older Adults With Hearing Loss in Their Daily Lives?
Status: COMPLETED
Conditions: Hearing Loss|Hearing Loss, Sensorineural|Emotions|Stress Physiology
Interventions: DEVICE: Bilateral hearing devices
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Lenalidomide Plus Bendamustine and Rituximab for Untreated CLL/SLL
Status: COMPLETED
Conditions: Chronic Lymphocytic Leukemia|Small Lymphocytic Lymphoma|B Chronic Lymphocytic Leukemia
Interventions: DRUG: Lenalidomide|DRUG: Bendamustine|DRUG: Rituximab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Explanation About Sleep in Post Trauma Patients
Status: UNKNOWN
Conditions: Post Traumatic Stress Disorder|Sleep Deprivation
Interventions: BEHAVIORAL: Explanation encouraging sleep|BEHAVIORAL: Explanation discouraging sleep|DRUG: Lorazepam
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: PK, Dose Proportionality, Food Effect And Repeat Dose Study Of Rosiglitazone XR In Healthy Volunteers
Status: COMPLETED
Conditions: Alzheimer's Disease
Interventions: DRUG: Rosiglitazone XR
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Abrilumab (AMG 181) in Adults With Moderate to Severe Ulcerative Colitis
Status: COMPLETED
Conditions: Ulcerative Colitis
Interventions: BIOLOGICAL: Abrilumab|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inflammatory Markers and Incidence of Comorbidities in Patients on Antiretroviral Therapy With Second-generation Anti-integrase Drugs on Triple Versus Dual Therapy
Status: RECRUITING
Conditions: Hiv
Interventions: OTHER: plasma inflammatory markers|OTHER: CD4/CD8 ratio
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Timing of PDA Closure and Respiratory Outcome in Premature Infants
Status: TERMINATED
Conditions: Patent Ductus Arteriosus
Interventions: DRUG: Early ibuprofen|OTHER: Late ibuprofen expectant group (placebo)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT