pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years
Status: COMPLETED
Conditions: HIV-1
Interventions: DRUG: Rilpivirine|DRUG: Zidovudine|DRUG: Abacavir|DRUG: Tenofovir disoproxil fumarate|DRUG: Lamivudine|DRUG: Emtricitabine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effects of Virtual Reality Based Rehabilitation in Acute Stroke Patients in an Inpatient Rehab Setting
Status: WITHDRAWN
Conditions: Stroke Syndrome|Hemiplegia
Interventions: DEVICE: Rapael
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Internal Limiting Membrane Peeling in Proliferative Diabetic Retinopathy
Status: ACTIVE_NOT_RECRUITING
Conditions: Diabetic Retinopathy Visually Threatening
Interventions: PROCEDURE: ILM Peeling|PROCEDURE: No ILM Peeling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Primary Care Behavioral Health (PCBH) With the Addition of Self-help CBT - A Randomized Multicenter Trial
Status: RECRUITING
Conditions: Panic Disorder|Social Anxiety Disorder|Depression|Hypochondriasis|Insomnia|Generalized Anxiety Disorder|Burnout|Adjustment Disorders|Stress, Psychological|Obsessive-Compulsive Disorder|Life Stress|Life Style Induced Illness|Psychological Distress
Interventions: BEHAVIORAL: Brief interventions|BEHAVIORAL: Self-help CBT
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Observational Registry Study: FIREHAWK DES for Treating Coronary Artery Disease (CAD)
Status: COMPLETED
Conditions: Coronary Artery Disease
Interventions: DEVICE: FIREHAWK biodegradable polymer rapamycin-eluting stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Estradiol-mediated Neural Plasticity as Potential Mediator of Neurofeedback Treatment Change for Traumatized Women
Status: UNKNOWN
Conditions: Posttraumatic Stress Disorder (PTSD)
Interventions: DEVICE: EFP-NF training
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)
Status: RECRUITING
Conditions: Primary Biliary Cholangitis|Compensated Cirrhosis|Hepatic Impairment
Interventions: DRUG: Seladelpar 10 mg|DRUG: Seladelpar 10 mg or less
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: PRIDE: Preventing Respiratory Illnesses During Childhood Study
Status: COMPLETED
Conditions: Tobacco Smoke Pollution
Interventions: BEHAVIORAL: Motivational Interviewing Intervention for ETS Reduction|BEHAVIORAL: Educational Program for ETS Reduction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Camostat Mesylate for Protein-losing Enteropathy After Fontan Operation
Status: NOT_YET_RECRUITING
Conditions: Fontan Operation|Protein-Losing Enteropathy|Camostat Mesylate
Interventions: DRUG: Camostat mesylate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Botox for Non-surgical Lateral Release in Patellofemoral Pain
Status: TERMINATED
Conditions: Patellofemoral Pain Syndrome
Interventions: DRUG: Botulinum toxin A + exercise|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Exploratory Study of Intrapulmonary Microdosing of Gram-negative Optical Imaging Detection Probe
Status: COMPLETED
Conditions: Respiratory Infections
Interventions: OTHER: BAC TWO|DEVICE: FE and Cellvizio viewer software
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Neural Changes Following Cognitive Behavior Therapy for Procrastination
Status: RECRUITING
Conditions: Procrastination
Interventions: BEHAVIORAL: Psychoeducation and cognitive modules|BEHAVIORAL: Behavioral module: Starting on Time and Planning Realistically|BEHAVIORAL: Behavioral module: Working Time Restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment Outcomes in Japanese RCC Patients Treated With Avelumab Plus Axitinib as First-line Therapy: Retrospective Study (J-DART2)
Status: COMPLETED
Conditions: Renal Cell Carcinoma
Interventions: DRUG: avelumab|DRUG: axitinib
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: A Study of Adebrelimab Combined With Chemoradiotherapy in the Treatment of Esophageal Small Cell Carcinoma
Status: NOT_YET_RECRUITING
Conditions: Esophageal Small Cell Carcinoma
Interventions: DRUG: Etoposide|DRUG: Cisplatin|DRUG: Carboplatin|DRUG: Adebrelimab|RADIATION: radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Tolerance and Development of Healthy, Term Infants
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: Alternate protein infant formula|OTHER: Standard infant formula
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effects of California Walnuts on Vascular Function in Postmenopausal Women
Status: COMPLETED
Conditions: Cardiovascular Diseases
Interventions: OTHER: Walnuts|OTHER: Walnuts|OTHER: Walnuts|OTHER: Walnuts
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Study to Assess the Efficacy of Budesonide/Albuterol Metered-dose Inhaler (BDA MDI/PT027) on Exercise-induced Bronchoconstriction in Adults and Adolescents With Asthma
Status: COMPLETED
Conditions: Exercise Induced Bronchospasm
Interventions: COMBINATION_PRODUCT: Budesonide/albuterol sulfate metered-dose inhaler 160/180 μg|COMBINATION_PRODUCT: Placebo metered-dose inhaler
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Safety and Efficacy of Wide Awake Local Anesthesia no Tourniquet Technique (WALANT) in Ankle Removal of Implant Surgery
Status: RECRUITING
Conditions: Safety Issues|Post Operative Pain|Local Anesthetic Complication
Interventions: PROCEDURE: Wide awake local anaesthesia no tourniquet technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: DART Electrical Impedance Myography (EIM) Trial in Duchenne Muscular Dystrophy (DMD) and Healthy Controls
Status: COMPLETED
Conditions: Duchenne Muscular Dystrophy
Interventions: OTHER: Testing with EIM
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose:
Clinical trial: Study of Motavizumab (MEDI-524) and Palivizumab Administered Sequentially in the Same Respiratory Syncytial Virus (RSV) Season
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections|Chronic Lung Disease and <= 24 Months of Age or|Premature With Gestational Age <=35 Weeks and <=6 Months of Age
Interventions: BIOLOGICAL: Motavizumab, palivizumab|BIOLOGICAL: Palivizumab, motavizumab|BIOLOGICAL: Motavizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Enteral Feeding of Fibre to Improve Microbiota
Status: RECRUITING
Conditions: Bowel Dysfunction|Colon Disease|Ileum--Diseases
Interventions: DIETARY_SUPPLEMENT: Soluble Fibre
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Open Label Safety and Tolerability Study of COV155 in Subjects With Osteoarthritis (OA) or Chronic Low Back Pain (CLBP)
Status: COMPLETED
Conditions: Osteoarthritis, Knee|Osteoarthritis, Hip|Chronic Low Back Pain
Interventions: DRUG: COV155
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Phase 1 Study of TG02 Citrate in Patients With Advanced Hematological Malignancies
Status: COMPLETED
Conditions: AML|ALL|Blast Crisis|MDS|Multiple Myeloma
Interventions: DRUG: TG02 citrate|DRUG: Carfilzomib|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of AN-PEP Enzyme on Gluten Digestion in Gluten Sensitive Individuals
Status: COMPLETED
Conditions: Non-coeliac Gluten Sensitivity
Interventions: DIETARY_SUPPLEMENT: AN-PEP|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of the Use of Energy Substrates and Hormonal Regulation of Blood Sugar During Exercise of Increasing Intensity Between Children With Type 1 Diabetes and Non-diabetic Control Children.
Status: UNKNOWN
Conditions: Type 1 Diabetes
Interventions: PROCEDURE: controlled physical activity
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: Does Concurrent Hydrocortisone With Venlafaxine XR Speed Antidepressant Response?
Status: COMPLETED
Conditions: Depressive Disorder, Major
Interventions: DRUG: venlafaxine XR|DRUG: hydrocortisone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Combination Analgesia for Neonatal Circumcision
Status: COMPLETED
Conditions: Analgesia
Interventions: DRUG: Sucrose|DRUG: Lidocaine|DRUG: EMLA Topical Product
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effects of Laser Therapy on Muscle Function in COPD Patients
Status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease|Fatigue
Interventions: OTHER: Laser therapy|OTHER: Placebo laser therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Bioabsorbable/Nufairy Coil Application Trial in China
Status: ACTIVE_NOT_RECRUITING
Conditions: Intracranial Aneurysm
Interventions: DEVICE: Nufairy® Coil embolization system for intracranial aneurysm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE)
Status: WITHDRAWN
Conditions: Osteoarthritis, Knee
Interventions: DRUG: High-dose/short-duration Fisetin|DRUG: Low-dose/sustained-duration Fisetin|OTHER: Oral placebo capsule
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Pilot Study of the Effects of Diet and Behavioral Interventions on Health in Diabetics
Status: COMPLETED
Conditions: Diabetes Type II
Interventions: BEHAVIORAL: Low Carbohydrate Diet|BEHAVIORAL: American Diabetes Association Diet|BEHAVIORAL: Mindfulness and Positive Affect Skills
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: 17-AAG and Sorafenib in Treating Patients With Unresectable or Metastatic Solid Tumors
Status: COMPLETED
Conditions: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: DRUG: sorafenib tosylate|DRUG: tanespimycin|OTHER: laboratory biomarker analysis|OTHER: pharmacological study|PROCEDURE: magnetic resonance imaging
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive Surgery
Status: COMPLETED
Conditions: Ocular Discomfort
Interventions: DRUG: rhNGF|OTHER: Vehicle
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Trial of Remdesivir in Adults With Mild and Moderate COVID-19
Status: SUSPENDED
Conditions: COVID-19|SARS-CoV-2
Interventions: DRUG: Remdesivir|DRUG: Remdesivir placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of PDR001 in Combination With CJM112, EGF816, Ilaris® (Canakinumab) or Mekinist® (Trametinib)
Status: COMPLETED
Conditions: Colorectal Cancer, Triple Negative Breast Cancer, NSCLC - Adenocarcinoma
Interventions: BIOLOGICAL: PDR001|BIOLOGICAL: ACZ885|BIOLOGICAL: CJM112|DRUG: TMT212|DRUG: EGF816
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sphenopalatine Ganglion Nerve Block for Postdural Puncture Headache in Obstetrics
Status: WITHDRAWN
Conditions: Postdural Puncture Headache|Cerebrospinal Fluid Leak|Spinal; Puncture, Complications, Headache
Interventions: DRUG: Lidocaine 4%|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Use of an Adjustable Single 8-0 Polypropylene Suture of Scleral Fixation Without Conjunctival Dissection
Status: COMPLETED
Conditions: Suture, Complication
Interventions: PROCEDURE: Novel use of an adjustable single 8-0 polypropylene suture of scleral fixation without conjunctival dissection
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Capture of Prostatic Trans-rectal Ultrasound Scans for Research
Status: SUSPENDED
Conditions: Prostate Cancer|Prostate Neoplasm
Interventions: PROCEDURE: Transrectal ultrasound scan of prostate
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Modulation of the Intestinal Microbiome by a High Protein Diet
Status: COMPLETED
Conditions: Obesity
Interventions: DIETARY_SUPPLEMENT: Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass|DIETARY_SUPPLEMENT: Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: In Vivo PARP-1 Expression With 18F-FTT PET/CT in Pancreatic Cancer
Status: TERMINATED
Conditions: Pancreatic Cancer
Interventions: DRUG: [18F]FluorThanatrace ([18F]FTT)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Repetitive Transcranial Magnetic Stimulation (rTMS) as an add-on Treatment for Resistant Obsessive-compulsive Symptoms in Patients With Schizophrenia
Status: COMPLETED
Conditions: Schizophrenia|Obsessive-Compulsive Symptoms
Interventions: DEVICE: Active rTMS|DEVICE: SHAM rTMS
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age
Status: COMPLETED
Conditions: Partial Seizures
Interventions: DRUG: Levetiracetam
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Computer Monitor vs Augmented Reality 3MDR for PTSD PTSD: A Randomized Controlled Trial
Status: RECRUITING
Conditions: Stress Disorders, Post-Traumatic
Interventions: OTHER: Motion-assisted, Multi-modular Memory Desensitization and Reconsolidation (3MDR)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Increasing COVID-19 Vaccine Uptake in Developing Countries (Bihar)
Status: COMPLETED
Conditions: Vaccination Refusal
Interventions: BEHAVIORAL: Incentives to be vaccinated|DEVICE: Mask|BEHAVIORAL: Encouragement to wear a mask|BEHAVIORAL: Vaccination made more convenient|BEHAVIORAL: Social mobilization campaign to be vaccinated
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCP
Status: COMPLETED
Conditions: Bile Duct Carcinoma|Gallbladder Carcinoma|Pancreatic Ductal Adenocarcinoma
Interventions: PROCEDURE: Endoscopic Retrograde Cholangiopancreatography|PROCEDURE: Endoscopic Retrograde Cholangiopancreatography
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Self-Management for Amputee Rehabilitation Using Technology.
Status: RECRUITING
Conditions: Behavior|Amputation|Lower Limb Amputation Above Knee (Injury)|Lower Limb Amputation Below Knee (Injury)|Lower Limb Amputation Knee
Interventions: BEHAVIORAL: SMART|BEHAVIORAL: Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Lipoic Acid and Omega-3 Fatty Acids for Cognitive Impairment in Multiple Sclerosis
Status: COMPLETED
Conditions: Multiple Sclerosis|Cognition
Interventions: DRUG: lipoic acid and omega-3 fatty acids|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ketamine Associated With Morphine PCA After Total Hip Arthroplasty
Status: COMPLETED
Conditions: Arthroplasty, Replacement, Hip
Interventions: DRUG: Ketamine-Morphine|DRUG: Morphine|DRUG: Postoperative PCA of Ketamine and morphine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Health Promotion Intervention for Vulnerable School
Status: COMPLETED
Conditions: Obesity|Health Promotion|Noncommunicable Diseases|Child Development|Life Style
Interventions: BEHAVIORAL: Intervention program BeE-school
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Evaluation of the Safety and Efficacy of N-desmethylclobazam in Patients With Peripheral Neuropathic Pain
Status: SUSPENDED
Conditions: Neuropathic Pain
Interventions: DRUG: NDMC
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: HAI Abraxane With Gemcitabine and Bevacizumab
Status: COMPLETED
Conditions: Advanced Cancers
Interventions: DRUG: HAI Abraxane|DRUG: Gemcitabine|DRUG: Bevacizumab|DRUG: Filgrastim
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement
Status: RECRUITING
Conditions: Systemic Inflammatory Response|Aortic Valve Stenosis
Interventions: DRUG: Placebo|DRUG: Dexmedetomidine 0.5mcg/kg/h|DRUG: Dexmedetomidine 1 mcg/kg/h
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Adjuvant Chemotherapy for Locally Advanced Cervical Cancer
Status: UNKNOWN
Conditions: Uterine Cervical Cancer
Interventions: RADIATION: Pelvic radiation|DRUG: Cisplatin|DRUG: Paclitaxel|DRUG: Carboplatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effects of Carperitide on Short and Long-term Prognosis in Patients With Both Cardiac and Renal Failure
Status: TERMINATED
Conditions: Heart Failure|Renal Failure
Interventions: DRUG: Carperitide heart failure therapy|DRUG: Standard heart failure therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: PET/CT Characterization of Treatment Resistance
Status: RECRUITING
Conditions: Prostate Cancer
Interventions: DIAGNOSTIC_TEST: F-fluorodeoxyglucose positron emission tomography (FDG PET)|DIAGNOSTIC_TEST: prostate-specific membrane antigen positron emission tomography (PSMA PET)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: OnTrack>An Online Role-Playing Game: A Small Business Innovation Research (SBIR) Grant
Status: COMPLETED
Conditions: Psychosis|Schizoaffective Disorder|Schizophrenia
Interventions: BEHAVIORAL: Behavioral/Attitudinal OnTrack Role-Playing Game
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Individualized Treatment of Acute Achilles Tendon Rupture
Status: ACTIVE_NOT_RECRUITING
Conditions: Achilles Tendon Rupture
Interventions: PROCEDURE: Individualized treatment of Acute Achilles tendon rupture.|PROCEDURE: Non-operative treatment|PROCEDURE: Operative treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Evaluate the Effect of Dry Needling on the Temporomandibular Joint in Subjects Who Have Suffered a Whiplash as a Result of a Traffic Accident
Status: RECRUITING
Conditions: Whiplash|Temporomandibular Joint Pain|Dry Needling Technique
Interventions: PROCEDURE: Dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Selinexor in Combination With R-CHOP Followed by Selinexor Maintenance for Untreated EBV-positive DLBCL Patients
Status: RECRUITING
Conditions: EBV-Positive Diffuse Large B-Cell Lymphoma, Nos
Interventions: DRUG: Selinexor|DRUG: R-CHOP Protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Clinical Outcomes and Decision-making Choice of Skull Base Approaches for Petroclival Meningiomas
Status: COMPLETED
Conditions: Skull Base Meningioma
Interventions: PROCEDURE: retrosigmoid approach (RSA)|PROCEDURE: subtemporal transtentorial transpetrosal approach (STTA)|PROCEDURE: extended pterional transtentorial approach (EPTA)|PROCEDURE: pretemporal trancavernous anterior transpetrosal approach (PTCA)|PROCEDURE: presigmoid combined supra-infratentorial approach (PCA)|PROCEDURE: inoperable
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Comparison Between Etview Tracheoscopic Ventilation Tube - TVT to Standard Endotracheal Intubation
Status: COMPLETED
Conditions: Endotracheal Intubation
Interventions: DEVICE: ETview TVT endotracheal tube|DEVICE: Endotracheal tube
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose:
Clinical trial: Continuation Ketamine in Major Depression
Status: COMPLETED
Conditions: Major Depressive Disorder
Interventions: DRUG: Lithium|DRUG: Ketamine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: T Cell Immunotherapy for Multiple Myeloma Patients Undergoing a Bone Marrow Transplant
Status: UNKNOWN
Conditions: Multiple Myeloma
Interventions: PROCEDURE: Infusion of Activated & Expanded Autologous T Cells
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Insomnia Prevalence and Treatment Impact on Systemic Hypertension
Status: TERMINATED
Conditions: Insomnia|Hypertension
Interventions: DRUG: Ramelteon (RozeremR)|BEHAVIORAL: sleep hygiene
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Reducing Respiratory Side Effects of Interscalene Brachial Plexus Block
Status: UNKNOWN
Conditions: Adverse Reaction to Peripheral Nerve- and Plexus-blocking Anesthetics
Interventions: OTHER: Interscalene brachial plexus block
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Effect of Otamixaban Versus Unfractionated Heparin + Eptifibatide in Patients With Unstable Angina/Non ST Elevation Myocardial Infarction Undergoing Early Invasive Strategy
Status: COMPLETED
Conditions: Acute Coronary Syndrome
Interventions: DRUG: Otamixaban|DRUG: Placebo (for Otamixaban)|DRUG: UFH|DRUG: Placebo (for UFH)|DRUG: Eptifibatide|DRUG: Placebo (for Eptifibatide)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: High Flow Oxygen Therapy in Patients Suffering From Chronic Obstructive Pulmonary Disease Exacerbation: Effects and Mechanisms of Action
Status: UNKNOWN
Conditions: COPD Exacerbation
Interventions: DEVICE: High flow humidified oxygen|DEVICE: Standard flow humidified oxygen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
Status: COMPLETED
Conditions: Cervical Cancer|Anal Cancer|Penile Cancer
Interventions: BEHAVIORAL: Personalized Chatbot Intervention|BEHAVIORAL: Non-Personalized Chatbot Intervention|BEHAVIORAL: No Chatbot Control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Safety and Efficacy of Probuphine in the Treatment of Opioid Dependence
Status: COMPLETED
Conditions: Opioid Dependence
Interventions: DRUG: Probuphine|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Ultrasound Guided Closed Reduction of Depressed Zygomatic Arch Fractures
Status: UNKNOWN
Conditions: Zygomatic Arch Fracture
Interventions: DEVICE: Intraoperative ultrasound guided|OTHER: Conventional blind reduction technique
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Study of Lanreotide in Patients With Metastatic Gastrointestinal Neuroendocrine Tumors Who Are Undergoing Liver-directed Radioembolization With Yttrium-90 Microspheres
Status: TERMINATED
Conditions: Neuroendocrine Tumors|Gastrointestinal Neoplasms|Carcinoid Tumors
Interventions: DRUG: Lanreotide|DEVICE: Y-90 microspheres
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Effects of Orchiectomy and Age on Vascular and Metabolic Health in Older Versus Younger Transgender Women
Status: RECRUITING
Conditions: Transgender|Gender Identity|Vascular Stiffness|Vascular Inflammation|Insulin Sensitivity|Blood Pressure|Lipid Disorder|Appetitive Behavior
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery
Status: RECRUITING
Conditions: Congenital Heart Disease
Interventions: OTHER: blood use for priming cardiopulmonary bypass circuit|OTHER: clear prime for cardiopulmonary bypass
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: The BEE-Power Study (Boosting Exercise for Excellent Pediatric Blood Pressure)
Status: NOT_YET_RECRUITING
Conditions: High Blood Pressure|Overweight and Obesity|Adolescent Obesity|Exercise
Interventions: OTHER: Aerobic exercise|OTHER: Isometric exercise
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Evaluating RXI-109 to Reduce the Progression of Subretinal Fibrosis in Subjects With NVAMD
Status: UNKNOWN
Conditions: Age-related Macular Degeneration|Subfoveal Choroidal Neovascularization|Subretinal Scarring|Subretinal Fibrosis
Interventions: DRUG: RXI-109
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF
Status: RECRUITING
Conditions: Heart Failure With Preserved Ejection Fraction|Hypertension
Interventions: DRUG: Amlodipine Besylate|DRUG: Metoprolol Succinate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Efficacy of MySkin Patch for the Healing of Burn Wounds: a Randomised Controlled Trial
Status: UNKNOWN
Conditions: Burns|Burn Injury|Hydrogel Bandage|Occlusive Dressings
Interventions: DEVICE: MySkin patch|DEVICE: Traditional Dressing
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: IVF Treatment in Women With Immature Oocytes in Previous Cycle
Status: COMPLETED
Conditions: Infertility
Interventions: DRUG: GnRH agonist 0.2 mg + hCG 250 mcg|DRUG: high dose hCG 500 mcg
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Neoadjuvant Nimotuzumab Plus Gemcitabine and Carboplatin in Unresectable Stage III Squamous Cell Lung Carcinoma
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DRUG: Nimotuzumab|DRUG: Gemcitabine|DRUG: Carboplatin|PROCEDURE: Surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluation of the Efficiency of the Bone Substitute Cerament-G Locally Delivering Gentamicin in the Treatment of Chronic Osteomyelitis of Long Bones
Status: RECRUITING
Conditions: Osteomyelitis Chronic
Interventions: PROCEDURE: Corticotomy and use of the bone substitute : Cerament-G device.|PROCEDURE: Corticotomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Natural Killer Index From Hematopoietic Stem Cell Graft
Status: COMPLETED
Conditions: Acute Lymphoblastic Leukemia|Acute Myeloblastic Leukemia|Chronic Myeloid Leukemia
Interventions: PROCEDURE: Blood test
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: The Effects of Different Lipid Emulsions on the Adipokines in Critically Ill Patients With Sepsis
Status: COMPLETED
Conditions: Sepsis
Interventions: OTHER: Olive oil-based intravenous fat emulsions|OTHER: Soybean-based intravenous fat emulsions
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: DESCARTES: De-ESCAlation of RadioTherapy in Patients With Pathologic Complete rESponse to Neoadjuvant Systemic Therapy
Status: NOT_YET_RECRUITING
Conditions: Breast Cancer
Interventions: RADIATION: Omission of radiotherapy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: SUPER Study (Substance Use and PTSD Treatment Effectiveness Research Study)
Status: COMPLETED
Conditions: Substance Use Disorders|Posttraumatic Stress Disorder
Interventions: BEHAVIORAL: Modified Seeking Safety integrated into std outpatient SUD care|BEHAVIORAL: Standard outpatient SUD care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Examining the Effectiveness of Deep TMS in Veterans With Alcohol Use Disorder
Status: ACTIVE_NOT_RECRUITING
Conditions: Alcohol Use Disorder (AUD)|Transcranial Magnetic Stimulation
Interventions: DEVICE: Deep Transcranial Magnetic Stimulation (dTMS) H7 coil
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Sit-to-Stand Progression Using Movi Chair vs Traditional Practices
Status: WITHDRAWN
Conditions: Physical Activity
Interventions: OTHER: Standard-of-Care Therapy + Sit-to-Stand Therapy|OTHER: Standard-of-Care Therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Aromatherapy Application With Bergamot and Grapefruit Essential Oils on PMS
Status: RECRUITING
Conditions: Premenstrual Syndrome-PMS
Interventions: OTHER: Bergamot Essential Oil|OTHER: Grapefruit Essential Oil|OTHER: Sweet almond oil
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Phase II Study of a B7-1 Gene-Modified Autologous Tumor Cell Vaccine and Systemic IL-2
Status: COMPLETED
Conditions: Kidney Cancer
Interventions: BIOLOGICAL: Interleukin-2|BIOLOGICAL: B7-1
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Curcumin; Rose Bengal; Denture Stomatitis
Status: UNKNOWN
Conditions: Candida Albicans Infection|Cigarette Smoking
Interventions: DRUG: Curcumin|DRUG: Rose Bengal|DRUG: Nystatin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Ablative Radiotherapy to Restrain Every Metastasis Safely Treatable (ARREST-2): A Randomized Phase II/III Trial
Status: RECRUITING
Conditions: Metastatic Cancer
Interventions: RADIATION: Arm 2: SABR|RADIATION: Arm 1: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial
Status: RECRUITING
Conditions: Crohn Disease|Azathioprine|Methotrexate
Interventions: DRUG: AZA capsules|DRUG: MTX|BIOLOGICAL: blood sample
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dexmedetomidine-esketamine Combined Nasal Administration and Perioperative Sleep Quality
Status: RECRUITING
Conditions: Breast Cancer|Perioperative Period|Dexmedetomidine|Esketamine|Sleep Quality
Interventions: DRUG: Dexmedetomidine|DRUG: Esketamine|DRUG: Normal saline
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Epithelial Mesenchymal Transition and Periodontitis
Status: UNKNOWN
Conditions: Periodontitis|Periodontal Diseases|Epithelial-Mesenchymal Transition|Transcription Factors|Epithelial Attachment|Gram-Negative Bacteria
Interventions: PROCEDURE: Modified Widman flap|PROCEDURE: Gingivectomy
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: SingapOre Lung Cancer Screening Through Integrating CT With Other biomarkErs (SOLSTICE)
Status: RECRUITING
Conditions: Lung Cancer
Interventions: DIAGNOSTIC_TEST: Low-dose CT of the Chest (LDCT) + Sampling for Biomarker Assays
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: The Effectiveness of Cow's Milk Immune Globulin in the Treatment of AIDS-Related Diarrhea
Status: COMPLETED
Conditions: Cryptosporidiosis|HIV Infections
Interventions: DRUG: Cryptosporidium Immune Whey Protein Concentrate (Bovine)
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Treatment of Relapsed Promyelocytic Leukemia With Arsenic Trioxide (ATO)
Status: COMPLETED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: Arsenic Trioxide|PROCEDURE: Autologous Transplantation|PROCEDURE: Allogenic Transplantation|DRUG: ATRA
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Ear Plugs Versus Acupressure for Management of Severe Gag Reflex
Status: UNKNOWN
Conditions: Gagging
Interventions: OTHER: Earplugs|OTHER: Acupressure|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Wedge Resection or Parietal Pleurectomy for the Treatment of Recurrent Pneumothorax (WOPP)
Status: ACTIVE_NOT_RECRUITING
Conditions: Pneumothorax|Recurrent Pneumothorax
Interventions: PROCEDURE: wedge resection|PROCEDURE: parietal pleurectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Azilsartan Medoxomil (TAK-491) Compared to Valsartan in Chinese Participants With Hypertension
Status: COMPLETED
Conditions: Essential Hypertension
Interventions: DRUG: Azilsartan medoxomil|DRUG: Valsartan|DRUG: Azilsartan medoxomil Placebo|DRUG: Valsartan Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study to Evaluate the Efficacy and Safety of AST-001 in ASD Children
Status: RECRUITING
Conditions: Autism Spectrum Disorder
Interventions: DRUG: AST-001|DRUG: Placebo of AST-001
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Antenatal Rescue Course of Glucocorticoids in Threatened Premature Birth
Status: TERMINATED
Conditions: Respiratory Distress Syndrome|Intraventricular Haemorrhage
Interventions: DRUG: Betamethasone sodium phos (drug)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE|Primary Purpose: PREVENTION
Clinical trial: The Effect of Smoking and Non-surgical Periodontal Treatment on Gingival Crevicular Fluid Cyclophilin A and EMMPRIN Levels
Status: COMPLETED
Conditions: Smoking|Periodontitis|Non-surgical Periodontal Treatment
Interventions: PROCEDURE: non-surgical periodontal treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Long-Term TARP Vaccination Using a Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139
Status: COMPLETED
Conditions: Prostatic Neoplasms|Neoplasms of Prostate|Prostate Cancer|Cancer Of Prostate|Stage D0 Prostate Cancer
Interventions: BIOLOGICAL: Multi-epitope (ME) T-cell Receptor Alternate Reading Frame Protein (TARP) vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Capecitabine (Xeloda) and Peginterferon Alfa-2a (Pegasys) in Treatment-Naive Participants With Advanced Liver Cancer
Status: COMPLETED
Conditions: Carcinoma, Hepatocellular
Interventions: DRUG: Capecitabine|DRUG: Peginterferon alfa-2a
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Safety Study in Healthy Volunteers of the Single-Use Autoinjector Containing Placebo of BG9418 Interferon Beta-1a With a 25-Gauge × 1-Inch Needle
Status: TERMINATED
Conditions: Healthy
Interventions: DEVICE: 25G x 1" Needle Autoinjector
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Mometasone Furoate Cream Reduces Acute Radiation Dermatitis in Head and Neck Squamous Cell Carcinomas' Patients
Status: UNKNOWN
Conditions: Early Radiation Dermatitis
Interventions: DRUG: Mometasone Furoate Cream
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: HEALTH_SERVICES_RESEARCH
Clinical trial: Study to Compare Prescription Non-Steroidal Anti-Inflammatory Drug (NSAID) Changes, Health Care Utilization, Efficacy and Safety of Meloxicam 7.5 mg Versus Usual Care Administration of Prescription NSAIDs in a Managed Healthcare Setting in Patients With Osteoarthritis
Status: COMPLETED
Conditions: Osteoarthritis
Interventions: DRUG: Meloxicam|DRUG: NSAID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Prediction Model and Assisted Decision-making System of Fertilization Disorders
Status: RECRUITING
Conditions: Infertility
Interventions: DIAGNOSTIC_TEST: Accurate prediction of fertilization disorders and clinical decision support systems assist doctors in decision-making|DIAGNOSTIC_TEST: Clinicians follow a routine protocol
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children
Status: WITHDRAWN
Conditions: Wheeze
Interventions: DRUG: Beclomethasone|DRUG: Beclomethasone and Salbutamol|DRUG: Placebo|DEVICE: Aerochamber Max®
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Stellate Ganglion Block on Pharyngeal Dysphagia After Cerebralvascular Accident
Status: COMPLETED
Conditions: Dysphagia
Interventions: BEHAVIORAL: comprehensive rehabilitation|DRUG: Lidocaine hydrochloride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: β-Glucans and the Metabolic Syndrome - a Human Intervention Study Under BEST
Status: COMPLETED
Conditions: Healthy
Interventions: OTHER: no β-glucan|OTHER: oat β-glucan|OTHER: barley β-glucan|OTHER: mutant-barley β-glucan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Gingival Irritation Due to Bleaching Tray Design in an At-home Bleaching Treatment
Status: COMPLETED
Conditions: Gingival Inflammation
Interventions: DRUG: Conventional Tray (1 mm)|DRUG: Extended Tray (3 mm)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Trial to Learn How Safe AZD9550 is in People With or Without Type 2 Diabetes Who Are Overweight or Obese
Status: RECRUITING
Conditions: Non-alcoholic Steatohepatitis (NASH)
Interventions: DRUG: AZD9550|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Correlation Between Parameters and Prognosis of Cervical Single Open-door Surgery
Status: RECRUITING
Conditions: Cervical Spinal Stenosis
Interventions: PROCEDURE: cervical single open-door surgery
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Abundance of Human Papilloma Virus in Women by Taking Probiotic
Status: WITHDRAWN
Conditions: Human Papilloma Virus Infection
Interventions: BIOLOGICAL: probiotic|OTHER: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Physician-Initiated Trial Investigating the Efficacy of Endovascular Treatment of Femoropopliteal Arterial Stenotic Disease With the Biotronik Passeo-18 Lux Drug Releasing Balloon and the Biotronik Pulsar-18 Stent (Comparing With 4EVER Trial Results)
Status: COMPLETED
Conditions: Peripheral Vascular Disease
Interventions: DEVICE: Passeo-18 balloon|DEVICE: Passeo-18 Lux drug releasing balloon|DEVICE: Pulsar-18 stent
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Molecular Imaging of Norepinephrine Transporter (NET) Using [C-11]Methylreboxetine PET in Multiple Sclerosis
Status: UNKNOWN
Conditions: Multiple Sclerosis
Interventions: DRUG: [C-11]Methylreboxetine
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: DIAGNOSTIC