pankajmathur/National_Library_of_Medicine_Studies_data huggingface dataset:
Clinical trial: Remineralizing Potential of Biomimetic Scaffolds on Enamel White Spot Lesions
Status: NOT_YET_RECRUITING
Conditions: White Spot Lesion
Interventions: OTHER: Curodont repair Self- assembling peptide P11-4|OTHER: Ph-chi phosphorylated - nano-chitosan|OTHER: CCP-ACP " +ve control " Casein phosphopeptide amorphous calcium phosphate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: The Relationship Between Cardiac Output and Microvascular Visceral Blood Flow
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: OTHER: Administration of 0.9% NaCl solution|OTHER: Measurement of stroke volume|OTHER: Measurement of microvascular blood flow|OTHER: Administration of gelofusine
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Endocrine Impact of the Duodenal-jejunal Bypass Sleeve on Type 2 Diabetes - Potential Role of the Incretin Hormones
Status: COMPLETED
Conditions: Type 2 Diabetes|Obesity
Interventions: DEVICE: EndoBarrier Gastrointestinal Liner
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Topical Nasal Fluticasone Propionate in the Control of Allergic Rhinitis SymptomsPerene
Status: COMPLETED
Conditions: Perennial Allergic Rhinitis
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer
Status: UNKNOWN
Conditions: Pancreatic Cancer
Interventions: DRUG: Gemcitabine Oxaliplatin 5FU and Leucovorin
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Investigation of Central Sensitization Frequency and Related Factors in Axial Spondyloarthritis Patients
Status: COMPLETED
Conditions: Axial Spondyloarthritis|Central Sensitisation
Interventions: DIAGNOSTIC_TEST: Pressure pain threshold|DIAGNOSTIC_TEST: Temporal summation|DIAGNOSTIC_TEST: Conditioned pain modulation|DIAGNOSTIC_TEST: Central Sensitization Inventory|OTHER: Bath Ankylosing Spondylitis Disease Activity Index|OTHER: Ankylosing Spondylitis Quality of Life|OTHER: Istanbul Low Back Pain Disability Index|OTHER: Beck Depression Inventory|OTHER: Fatigue Severity Scale|OTHER: Pittsburgh Sleep Quality Index|OTHER: Fibromyalgia Rapid Screening Tool|OTHER: Visual analogue scale
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Stem Cell Transplant to Treat Patients With Systemic Sclerosis
Status: COMPLETED
Conditions: Systemic Sclerosis
Interventions: DRUG: Cyclophosphamide|DRUG: Mesna|DRUG: G-CSF|PROCEDURE: Leukopheresis|PROCEDURE: Total Body Irradiation
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Switching From Cigarette Smoking to THS on Systemic Endothelial Function in Subjects With Established Atherosclerotic Disease
Status: WITHDRAWN
Conditions: Cardiovascular Diseases|Smoking|Tobacco Use|Peripheral Arterial Disease|Coronary Artery Disease
Interventions: OTHER: Cigarette|OTHER: THS|OTHER: Smoking Abstinence
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: OTHER
Clinical trial: A Study To Investigate The Effect Of Inhaled Fluticasone Propionate On The Bronchial Responsiveness To Leukotriene D4 In Asthmatics Patients
Status: COMPLETED
Conditions: Asthma|Mild Asthma
Interventions: DRUG: FLIXOTIDE Diskus 500 mcg (Fluticasone Propionate)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Open-Label, Dose-Escalation Study of 2 to 5 IM Doses of MEDI-524 at 3 mg/kg or 15 mg/kg; Children to be Followed for 90 Days After Their Last Dose of MEDI-524
Status: COMPLETED
Conditions: Respiratory Syncytial Virus Infections
Interventions: BIOLOGICAL: Medi-524
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing the Efficacy of Local Anesthetics in Mohs Surgery
Status: UNKNOWN
Conditions: Lidocaine|Bupivacaine|Mohs Surgery|Anesthetic
Interventions: DRUG: Lidocaine|DRUG: Bupivacaine|DRUG: Lidocaine and Bupivacaine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005)
Status: COMPLETED
Conditions: Acute Promyelocytic Leukemia
Interventions: DRUG: ATRA|DRUG: Idarubicina|DRUG: Mitoxantrone|DRUG: ARA-C
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Use of Telmisartan and Captopril in Inflammation of Hemodialysis Patients
Status: COMPLETED
Conditions: Inflammation|End-stage Renal Disease
Interventions: DRUG: captopril plus placebo|DRUG: telmisartan plus placebo|DRUG: Telmisartan plus Captopril|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Creating Healthier Communities Through Meaningful Partnerships: A Model From the National African American Male Wellness Initiative - OSU Partnership
Status: COMPLETED
Conditions: Hypertension|Diabetes|Sedentary Behavior|High Cholesterol|Diet, Healthy|Smoking Reduction|Weight Loss
Interventions: OTHER: Physical Activity and Education Intervention
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: PREVENTION
Clinical trial: A Phase 2/3 Study to Evaluate FP-025 in Patients With Severe to Critical COVID 19
Status: TERMINATED
Conditions: Severe to Critical COVID 19 With Associated ARDS
Interventions: DRUG: FP-025 100 mg|DRUG: FP-025 300 mg|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Treating Postictal Symptoms Using Ibuprofen and Nifedipine
Status: RECRUITING
Conditions: Epilepsy|Epilepsies, Partial
Interventions: DRUG: Ibuprofen|DRUG: Nifedipine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multiforme
Status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Interventions: DRUG: dalteparin|RADIATION: radiation therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Effects of Dry Needling on Spasticity, Functions, Balance and Independence Level in Patients With Stroke
Status: COMPLETED
Conditions: Stroke|CVA (Cerebrovascular Accident)
Interventions: OTHER: Neurodevelopemental therapy (NDT)|OTHER: Neurodevelopemental therapy (NDT) and dry needling
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Replication Of An Early Evaluation Of 30-Day Readmissions Among Nonvalvular Atrial Fibrillation Patients Treated With Dabigatran, Rivaroxaban, Apixaban, or Warfarin In The U.S
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: dabigatran|DRUG: rivaroxaban|DRUG: apixaban|DRUG: warfarin
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Effects of Acute Caloric Deprivation on Odour Identification and Food Reward
Status: COMPLETED
Conditions: Olfaction|Diet|Exercise|Energy Depletion|Food Hedonics|Food Reward
Interventions: BEHAVIORAL: DIET|BEHAVIORAL: EX
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Inverting Grayscale Improves Detection of Proximal Femur Fracture
Status: UNKNOWN
Conditions: Diagnoses Disease
Interventions: DIAGNOSTIC_TEST: BIXAM
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure.
Status: TERMINATED
Conditions: Cystic Fibrosis|Chronic Respiratory Failure
Interventions: DEVICE: pressure support ventilator
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Comparing Carotid Stenting With Endarterectomy in Severe Asymptomatic Carotid Stenosis
Status: COMPLETED
Conditions: Carotid Stenosis
Interventions: PROCEDURE: carotid artery stenting|PROCEDURE: carotid endarterectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children
Status: NOT_YET_RECRUITING
Conditions: PTSD|Depression|Parent-Child Relations
Interventions: BEHAVIORAL: Parenting-STAIR|BEHAVIORAL: Treatment as Usual
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: A Study of Nipocalimab in Adult Participants With Active Systemic Lupus Erythematosus
Status: ACTIVE_NOT_RECRUITING
Conditions: Systemic Lupus Erythematosus
Interventions: OTHER: Placebo|DRUG: Nipocalimab|DRUG: Standard-of-care treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Diabetes and Periodontal Therapy Trial
Status: COMPLETED
Conditions: Chronic Periodontitis|Type 2 Diabetes
Interventions: PROCEDURE: Non-surgical periodontal therapy|OTHER: Delayed non-surgical periodontal therapy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Reducing Structural Inequities in Heart Failure Management: An Approach to Improve the Quality of Heart Failure Care on the General Medicine Service: Longitudinal Equity Action Plan (LEAP)
Status: UNKNOWN
Conditions: Heart Failure
Interventions: OTHER: Longitudinal Equity Action Plan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Omegia Softgel Clinical Research Program
Status: COMPLETED
Conditions: Skin Manifestations|Antioxidative Stress|Eye Strain|Vaginal Disease
Interventions: DIETARY_SUPPLEMENT: Omegia® Softgel -B|DIETARY_SUPPLEMENT: Omegia® Softgel -A
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Testosterone Replacement in Metabolic Syndrome and Inflammation
Status: COMPLETED
Conditions: Hypogonadism|Metabolic Syndrome|Obesity|Erectile Dysfunction
Interventions: DRUG: Testosterone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Ranitidine on Hyper-IgE Recurrent Infection (Job's) Syndrome
Status: TERMINATED
Conditions: JOB's Syndrome|Hyper-IgE Recurrent Infection Syndrome|Immune Deficiency
Interventions: DRUG: Ranitidine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Studying Biomarkers as a Diagnostic Tool in Samples From Younger Patients With B-Cell Acute Lymphoblastic Leukemia
Status: COMPLETED
Conditions: B-cell Childhood Acute Lymphoblastic Leukemia|Childhood Acute Lymphoblastic Leukemia in Remission|Recurrent Childhood Acute Lymphoblastic Leukemia
Interventions: OTHER: laboratory biomarker analysis
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Breast Tissue Before And After Breastfeeding Or The Use Of A Breast Pump
Status: COMPLETED
Conditions: To Collect Measurements of the Nipple|To Record Clinical Observations of the Nipple, Areola, and Breast Tissue Before and After Breastfeeding|To Record Clinical Observations of the Nipple, Areola, and Breast Tissue Before and After Expressing Milk With 3 Different Electric Breast Pumps.
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Magnetic Resonance Imaging for Detection of Peritoneal Mesothelioma
Status: COMPLETED
Conditions: Mesothelioma|Peritoneal Mesothelioma
Interventions: DIAGNOSTIC_TEST: HR-MRI|DIAGNOSTIC_TEST: Standard CT Imaging|DIAGNOSTIC_TEST: Ultrasound
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: SCREENING
Clinical trial: Brief ES for Recovery of Autonomic Function in CES
Status: RECRUITING
Conditions: Cauda Equina Syndrome
Interventions: DEVICE: Brief ES at the time of decompression for cauda equina syndrome|DEVICE: Brief ES to facilitate mcturition/removal of catheter
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Trastuzumab in Treating Older Women With Early-Stage Breast Cancer
Status: COMPLETED
Conditions: Breast Cancer
Interventions: BIOLOGICAL: trastuzumab|OTHER: laboratory biomarker analysis|PROCEDURE: adjuvant therapy|PROCEDURE: quality-of-life assessment
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cyclophosphamide and Dexamethasone for the Treatment of Metastatic Castration Resistant Prostate Cancer
Status: RECRUITING
Conditions: Castration-Resistant Prostate Carcinoma|Metastatic Prostate Adenocarcinoma|Stage IVB Prostate Cancer American Joint Committee on Cancer (AJCC) v8
Interventions: DRUG: Cyclophosphamide|DRUG: Dexamethasone
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study of mRNA-1010 Seasonal Influenza Vaccine in Adults
Status: COMPLETED
Conditions: Seasonal Influenza
Interventions: BIOLOGICAL: mRNA-1010|BIOLOGICAL: Licensed Quadrivalent Inactivated Seasonal Influenza Vaccine
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Fall Epidemic Viral Pediatric Study
Status: COMPLETED
Conditions: Asthma
Interventions: DRUG: FLOVENT™ DISKUS™ 100 mcg BID|DRUG: ADVAIR™ DISKUS™ 100/50 mcg BID
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow
Status: RECRUITING
Conditions: Elbow Pain|Chronic Pain
Interventions: DRUG: Diclofenac|DRUG: Tramadol|OTHER: Acetaminophen
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Scrambler Therapy for Corticobasal Syndrome-Associated Pain
Status: RECRUITING
Conditions: Corticobasal Degeneration|Corticobasal Syndrome|Pain, Neuropathic
Interventions: DEVICE: Scrambler therapy|DEVICE: TENS treatment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: A Study Comparing Swallowed Flovent and Placebo in Patients With Eosinophilic Disorders
Status: COMPLETED
Conditions: Eosinophilic Esophagitis
Interventions: DRUG: Fluticasone Propionate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Bed Rest After Preterm Premature Rupture of the Membranes
Status: COMPLETED
Conditions: Preterm Premature Rupture of Membrane
Interventions: BEHAVIORAL: complete bed rest|BEHAVIORAL: activity restriction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Flurbiprofen Versus Aloe Vera Gel in the Treatment of Chronic Periodontitis in Smoking Patients.
Status: COMPLETED
Conditions: Periodontitis Chronic Generalized Severe
Interventions: DRUG: 2.5% flurbiprofen|DRUG: 98% aloe vera|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Guidance of Thin Cross- Section of CT in Anatomic Segmentectomy
Status: COMPLETED
Conditions: Segmentectomy|Video- Assisted Thoracoscopic Surgery|Three-dimensional-computed Tomography (3D-CT)|Thin Cross- Section of CT
Interventions: OTHER: Cross- Section of CT Guided Anatomic Segmentectomy|OTHER: 3D simulation Guided Anatomic Segmentectomy
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: OTHER
Clinical trial: Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders
Status: COMPLETED
Conditions: Infertility, Female
Interventions: DRUG: Duphaston|DRUG: Gonadotropin|DRUG: Cetrotide Injectable Product|DRUG: Decapeptyl|DRUG: Chorionic Gonadotropin|DRUG: Combined Oral Contraceptive|DRUG: Cyclo-Progynova|DRUG: progesterone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Resminostat (4SC-201) in Relapsed or Refractory Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Hodgkin's Lymphoma
Interventions: DRUG: Resminostat (4SC-201)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of EE/NETA With Scaling on Periodontium and hsCRP in PCOS Women With Gingivitis
Status: COMPLETED
Conditions: Gingivitis|PCOS
Interventions: PROCEDURE: scaling and OHI|PROCEDURE: oral Hygiene instructions|PROCEDURE: Scaling and oral hygiene instruction
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Leucine Co-ingestion and Myofibrillar Protein Synthesis in Older Adults
Status: COMPLETED
Conditions: Aging|Sarcopenia
Interventions: DIETARY_SUPPLEMENT: Leucine|DIETARY_SUPPLEMENT: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: Gallium Nitrate in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma
Status: COMPLETED
Conditions: Lymphoma
Interventions: DRUG: cytarabine|DRUG: gallium nitrate|DRUG: leucovorin calcium|DRUG: methotrexate
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: |Masking: |Primary Purpose: TREATMENT
Clinical trial: Study Evaluating MYO-029 in Adult Muscular Dystrophy
Status: COMPLETED
Conditions: Becker Muscular Dystrophy|Facioscapulohumeral Muscular Dystrophy|Limb-Girdle Muscular Dystrophy
Interventions: DRUG: MYO-029
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE|Primary Purpose: TREATMENT
Clinical trial: Comparison of Inclined Backwalk vs Kneel Walk on Genurecurvatum in Hemiplegic Cerebral Palsy
Status: RECRUITING
Conditions: Hemiplegic Cerebral Palsy
Interventions: OTHER: Inclined Backwalk|OTHER: Knee Walk
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: OTHER
Clinical trial: DSM265 Chemoprophylaxis of Plasmodium Falciparum Malaria
Status: COMPLETED
Conditions: Plasmodium Falciparum, Malaria
Interventions: DRUG: DSM265 400mg|DRUG: Placebo to DSM265 400 mg|BIOLOGICAL: Plasmodium falciparum sporozoite challenge|DRUG: Malarone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Verbal Stimulation of Orientation on Emergence Agitation
Status: COMPLETED
Conditions: Emergence Delirium
Interventions: OTHER: Giving orientation with headphones|OTHER: Emergence as usual with headphones
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Study Comparing CUBICIN® (Daptomycin for Injection) With Vancomycin in Cellulitis or Erysipelas
Status: COMPLETED
Conditions: Cellulitis
Interventions: DRUG: Daptomycin|DRUG: Vancomycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE|Primary Purpose: TREATMENT
Clinical trial: Shigella WRSS1 Vaccine Trial in Bangladesh
Status: COMPLETED
Conditions: Diarrhea
Interventions: BIOLOGICAL: Shigella sonnei Strain WRSS1 Vaccine|BIOLOGICAL: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: A Study Comparing the Effect of Atomoxetine Versus Other Standard Care Therapy on the Long Term Functioning in Attention-Deficit/Hyperactivity Disorder (ADHD) Children and Adolescents
Status: COMPLETED
Conditions: Attention Deficit Hyperactivity Disorder
Interventions: DRUG: Atomoxetine|DRUG: Other standard therapy for ADHD
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: The Research of the Evaluation of Clinical Procedures in Gastroesophageal Varices in Patients With Liver Cirrhosis
Status: UNKNOWN
Conditions: Gastroesophageal Varice
Interventions: PROCEDURE: Ligation and Cyanoacrylate|PROCEDURE: Ligation plus Sclerotherapy and Cyanoacrylate Group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Randomized Controlled Trial to Evaluate High Tie Versus Low Tie of the Inferior Mesenteric Artery in Anterior Resection
Status: UNKNOWN
Conditions: Rectal Cancer|Colon Rectal Resection
Interventions: PROCEDURE: High tie of IMA|PROCEDURE: Low tie of IMA
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy
Status: COMPLETED
Conditions: Asthma; Eosinophilic|Asthma Chronic|Bronchial Asthma|Asthma, Bronchial
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Genetic Determinism of Epithelial Barrier Defects in Irritable Bowel Syndrome
Status: WITHDRAWN
Conditions: Irritable Bowel Syndrome (IBS)
Interventions: GENETIC: Analysis on colorectal biopsy
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of Diclofenac Capsules to Treat Pain Following Surgery in Children Ages 6 to <17 Years of Age
Status: COMPLETED
Conditions: Pain, Postoperative
Interventions: DRUG: Diclofenac Capsules low dose|DRUG: Diclofenac Capsules high dose
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Intrauterine Balloon Dilatation Therapy in the Prevention of Adhesion Formation After Hysteroscopic Myomectomy
Status: UNKNOWN
Conditions: Intrauterine Adhesion
Interventions: PROCEDURE: multiple myoma IUB dilatation group
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Renin-angiotensin-aldosterone System (RAAS), Inflammation, and Post-Operative Atrial Fibrillation (AF)
Status: COMPLETED
Conditions: Atrial Fibrillation
Interventions: DRUG: Placebo|DRUG: Ramipril|DRUG: Spironolactone
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Effects of NMES in Critically Ill Patients
Status: UNKNOWN
Conditions: Mechanical Ventilation Complication|Muscle Weakness Condition|Covid19
Interventions: DEVICE: neuromuscular electrical stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Glutamate Supplementation in Young Men
Status: COMPLETED
Conditions: Healthy
Interventions: DIETARY_SUPPLEMENT: MSG|DIETARY_SUPPLEMENT: CHO|DIETARY_SUPPLEMENT: Placebo A|DIETARY_SUPPLEMENT: Placebo B
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Microwave Ablation Simultaneously Combined With Lenavatinib for Recurrent Hepatocellular Carcinoma
Status: RECRUITING
Conditions: Hepatocellular Carcinoma|Microwave Ablation|Liver Cancer|Lenvatinib|Recurrent Tumor
Interventions: PROCEDURE: Microwave ablation|DRUG: Lenvatinib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Submucosal Saline Injection Followed by Endoscopic Ultrasound
Status: RECRUITING
Conditions: Esophageal Cancer
Interventions: PROCEDURE: Submucosal Saline Injection|PROCEDURE: Blue laser Imaging and Magnifying Endoscopy
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: DIAGNOSTIC
Clinical trial: A Multiple-Ascending Dose Study in Type 2 Diabetes Mellitus Patients
Status: COMPLETED
Conditions: Diabetes Mellitus, Type 2
Interventions: DRUG: LY2393910|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose:
Clinical trial: Comparative Study of Clinical Efficacy and Safety of GNR-069 and Nplate in Patients With ITP
Status: COMPLETED
Conditions: Idiopathic Thrombocytopenic Purpura
Interventions: BIOLOGICAL: GNR-069|BIOLOGICAL: Nplate
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: The Association of Resistance Exercise With the Inflammasome Activation in Obesity Subjects
Status: UNKNOWN
Conditions: Physical Activity|Resistance Exercise|Inflammation|Obesity
Interventions: BEHAVIORAL: Resistance exercise training plus hypocaloric diet|BEHAVIORAL: Hypocaloric diet
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: A Study of Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Doses of PHP-303 in Otherwise Healthy Overweight or Obese Subjects
Status: COMPLETED
Conditions: Otherwise Healthy Overweight or Obese
Interventions: DRUG: PHP-303|OTHER: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison of Diagnostic Performances of 68Ga-DOTATATE PET-CT and 18F-FDOPA PET-CT in Paragangliomas and Pheochromocytomas Evaluation
Status: COMPLETED
Conditions: Paragangliomas|Pheochromocytomas
Interventions: OTHER: PET-CT
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: DIAGNOSTIC
Clinical trial: Pharmacokinetic Study of Livalo® Fixed Combination Drug in Healthy Subjects
Status: COMPLETED
Conditions: Hyperlipidemia|Hypertension
Interventions: DRUG: Livalo fixed combination drug|DRUG: Pitavastatin, Valsartan
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: OTHER
Clinical trial: Pharmacokinetic Interaction Study of Steady-state Tipranavir/Ritonavir (TPV/r) With Single-dose Valaciclovir (VAL) in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Tipranavir|DRUG: Ritonavir|DRUG: Valaciclovir
Study Type: INTERVENTIONAL
Study Design: Allocation: |Intervention Model: CROSSOVER|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Dental Anxiety Management by Behavioral Therapeutic Techniques Among Iraqi Adult Patients Seeking Private Dental Care
Status: COMPLETED
Conditions: Dental Anxiety|Behavioral Management
Interventions: BEHAVIORAL: Cognitive behavioral therapy (CBT) by using Distraction technique.|BEHAVIORAL: Mindfulness technique by using of relaxation breathing with muscle relaxation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Pembrolizumab With Chemotherapy in Metastatic or Unresectable High Grade Gastroenteropancreatic or Lung Neuroendocrine Carcinoma
Status: WITHDRAWN
Conditions: Neuroendocrine Carcinoma|Large Cell Neuroendocrine Carcinoma of the Lung|High Grade Neuroendocrine Carcinoma, Any Site
Interventions: DRUG: Pembrolizumab
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB
Status: COMPLETED
Conditions: Tuberculosis
Interventions: DRUG: Meropenem Injection|DRUG: Amoxicillin Clavulanate|DRUG: Pyrazinamide|DRUG: Bedaquiline|DRUG: Rifafour
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Evaluating Anatomic Versus Targeted Lead Placement for Burst Stimulation Therapy During the Trial
Status: COMPLETED
Conditions: Chronic, Intractable Pain of the Trunk and/or Lower Limbs
Interventions: DEVICE: lead placement followed by BurstDR stimulation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, CARE_PROVIDER)|Primary Purpose: TREATMENT
Clinical trial: The Efficacy of Balance Gaming as an Adjunct to Vestibular Rehabilitation Therapy
Status: TERMINATED
Conditions: Vestibular Diseases|Disturbance; Balance, Labyrinth
Interventions: OTHER: Use of Nintendo Wii Balance Gaming system
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children
Status: COMPLETED
Conditions: Postoperative Nausea and Vomiting
Interventions: DRUG: dexamethasone|DRUG: Local anesthetic infiltration|DRUG: General anesthesia|PROCEDURE: Tonsillectomy|PROCEDURE: gastric content suction|DRUG: Tramadol hydrochloride|DRUG: Propacetamol hydrochloride|DRUG: Paracetamol Suppository
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer
Status: RECRUITING
Conditions: Lung Cancer, Non-Small Cell
Interventions: DRUG: Pembrolizumab|DRUG: Dostarlimab|DRUG: Belrestotug|DRUG: GSK6097608
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cryoprobe Versus Forceps for Transbronchial Biopsy
Status: ENROLLING_BY_INVITATION
Conditions: Lung Diseases
Interventions: DEVICE: ERBECRYO® 2 Cryosurgical Unit and Accessories - K190651|DEVICE: Radial Jaw 4 Pulmonary Biopsy Forceps
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: DIAGNOSTIC
Clinical trial: Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure
Status: COMPLETED
Conditions: Kidney Transplant
Interventions: DRUG: Rapamycin
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of a Novel Sweetener on the pH of Dental Plaque.
Status: COMPLETED
Conditions: Dental Caries
Interventions: OTHER: food - novel sweetener|OTHER: food vehicle blank|OTHER: food - sweetener, positive control|OTHER: food - sweetener, negative control
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: PREVENTION
Clinical trial: Comparison of Daily Home Hemodialysis (HD) With Conventional in Center HD in Terms of Patients Quality of Life and Clinical Outcomes
Status: UNKNOWN
Conditions: End Stage Renal Disease
Interventions: OTHER: Delivery of a connected pedometer / accelerometer
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Cognitive Enhancement and Risk-reduction Through Exercise for Brain-Related Outcomes
Status: ACTIVE_NOT_RECRUITING
Conditions: Aging
Interventions: BEHAVIORAL: BAILAMOS™ @home/en casa|BEHAVIORAL: ¡En Forma y Fuerte! @home/en casa
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: PREVENTION
Clinical trial: CER-001 Atherosclerosis Regression ACS Trial
Status: COMPLETED
Conditions: Acute Coronary Syndromes
Interventions: DRUG: CER-001|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Kinesio Taping on the Stability of Knee in Soccer Players
Status: COMPLETED
Conditions: Injury of Musculoskeletal System
Interventions: OTHER: Kinesio Taping placebo and exercises|OTHER: Kinesio Taping with tension and exercises|OTHER: Kinesio Taping with tension
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: FACTORIAL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Comparison Study of Brachytherapy and Endoscopic Stenting for Dysphagia in Esophago-Gastric Junction Cancer
Status: UNKNOWN
Conditions: Adenocarcinoma of the Esophago-gastric Junction
Interventions: RADIATION: Brachytherapy|PROCEDURE: Endoscopic stenting
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL
Status: RECRUITING
Conditions: Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Mixed Phenotype Acute Leukemia
Interventions: DRUG: MRX-2843
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Endoluminal Vacuum Therapy to Prevent Anastomotic Leakage After Esophagectomy Due to Esophageal Cancer
Status: NOT_YET_RECRUITING
Conditions: Esophageal Cancer|Esophagus Cancer|Anastomotic Leak
Interventions: DEVICE: Eso-SPONGE®
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ionis AGT-LRx in Healthy Volunteers
Status: COMPLETED
Conditions: Healthy Volunteers
Interventions: DRUG: Ionis AGT-LRx|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Multiple Meal Stable Iron Isotope Study in Iron Deficient Rwandese Women to Investigate the Performance of Low Phytic Acid Bean Seeds
Status: COMPLETED
Conditions: Enrichment of Blood With Stable Iron Isotopes
Interventions: DIETARY_SUPPLEMENT: 10 x 55 g/ bean per arm
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: SINGLE (PARTICIPANT)|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Novel Approach to Posterior Mesh Fixation in Laparoscopic Sacral Colpopexy
Status: UNKNOWN
Conditions: Pelvic Organ Prolapse
Interventions: PROCEDURE: laparoscopic sacral colpopexy with posterior mesh no attachment|PROCEDURE: laparoscopic sacral colpopexy with posterior mesh attachment
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Atopic Dermatitis Research Network (ADRN) Influenza Vaccine Pilot
Status: COMPLETED
Conditions: Atopic Dermatitis
Interventions: DRUG: Fluzone® Intradermal (Sanofi Pasteur Inc.)
Study Type: INTERVENTIONAL
Study Design: Allocation: NON_RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: BASIC_SCIENCE
Clinical trial: A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.
Status: COMPLETED
Conditions: Dyslipidemia|Hypercholesterolemia|High Cholesterol
Interventions: DRUG: Obicetrapib|DRUG: Obicetrapib
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges
Status: COMPLETED
Conditions: Myopia|Astigmatism
Interventions: DEVICE: comfilcon A Toric
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Denosumab (AMG 162) in Japanese Postmenopausal Women
Status: COMPLETED
Conditions: Osteoporosis
Interventions: DRUG: Placebo|BIOLOGICAL: Denosumab
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: TRIPLE (PARTICIPANT, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: REVEAL 2 Trial (Evaluation of VGX-3100 and Electroporation for the Treatment of Cervical HSIL)
Status: COMPLETED
Conditions: Cervical Dysplasia|Cervical High Grade Squamous Intraepithelial Lesion|HSIL
Interventions: BIOLOGICAL: VGX-3100|BIOLOGICAL: Placebo|DEVICE: CELLECTRA™-5PSP
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Dissemination of the Look Ahead Weight Management Treatment in the Military
Status: COMPLETED
Conditions: Overweight|Obesity
Interventions: BEHAVIORAL: Phone-based sessions (28 total) on a structured schedule|BEHAVIORAL: Phone-based sessions upon request|BEHAVIORAL: Weight self-monitoring|BEHAVIORAL: Dietary and physical activity self-monitoring|BEHAVIORAL: Scheduled tailored interventionist feedback|BEHAVIORAL: Dietary goals|BEHAVIORAL: Meal replacements|BEHAVIORAL: Physical activity goals|BEHAVIORAL: Toolbox|BEHAVIORAL: Challenges|BEHAVIORAL: Tailored interventionist feedback upon request
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Pediatric Radiation Oncology With Movie Induced Sedation Effect (PROMISE)
Status: RECRUITING
Conditions: Pediatric Cancer
Interventions: OTHER: PROMISE (Pediatric Radiation Oncology with Movie Induced Sedation Effect)
Study Type: INTERVENTIONAL
Study Design: Allocation: NA|Intervention Model: SINGLE_GROUP|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: A Study to Evaluate the Effect of Intranasal Esketamine on Cognitive Functioning in Healthy Subjects
Status: COMPLETED
Conditions: Healthy
Interventions: DRUG: Esketamine|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: A Blood and Tissue Sample Collection Study of Patients Who Have Inflammatory Bowel Disease, Who Have Been Treated With Adalimumab and Who Developed Hepatosplenic T-Cell Lymphoma
Status: WITHDRAWN
Conditions: Crohn's Disease|Ulcerative Colitis (UC)|Hepatosplenic T-Cell Lymphoma
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: The Tolerability and Pharmacokinetics Study of Kangdaprevir Sodium Tablet in Healthy Adult Subjects
Status: COMPLETED
Conditions: Chronic Hepatitis c
Interventions: DRUG: Kangdaprevir Sodium Tablet|DRUG: placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: SEQUENTIAL|Masking: QUADRUPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Novel Mobile Device Application to Improve Adherence
Status: COMPLETED
Conditions: Pediatric Heart Transplant Recipients|Pediatric Cardiac Transplantation|Pediatric Heart Transplantation
Interventions: OTHER: Teen Pocket PATH® Mobile Application|OTHER: Control Group: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: SUPPORTIVE_CARE
Clinical trial: Study to Evaluate the Immune Response and Safety of GSK Biologicals' HPV Vaccine in Healthy Women Aged 18-35 Years
Status: COMPLETED
Conditions: Infections, Papillomavirus
Interventions: BIOLOGICAL: Placebo|BIOLOGICAL: HPV-16/18 L1 VLP AS04 (Cervarix TM)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: PREVENTION
Clinical trial: Profiling the RCRSP Patient: a Pain Phenotype Classification Algorithm
Status: NOT_YET_RECRUITING
Conditions: Rotator Cuff Syndrome|Rotator Cuff Tears|Rotator Cuff Tendinosis|Rotator Cuff Impingement|Rotator Cuff Tear or Rupture, Not Specified as Traumatic
Interventions: DEVICE: Quantitative Sensory Testing / Dynamometry / Goniometry
Study Type: OBSERVATIONAL
Study Design: Observational Model: |Time Perspective: p
Clinical trial: Study Comparing the Safety and Efficacy of BOL-303259-X to Latanoprost in Subjects With Glaucoma or Ocular Hypertension
Status: COMPLETED
Conditions: Intraocular Pressure
Interventions: DRUG: BOL-303259-X|DRUG: Latanoprost
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (INVESTIGATOR)|Primary Purpose: SCREENING
Clinical trial: Clinical Evaluation of the Next Science SurgX Antimicrobial Wound Gel Impact on Surgical Site Complications
Status: NOT_YET_RECRUITING
Conditions: Total Hip Arthroplasty|Total Knee Arthroplasty
Interventions: OTHER: SurgX Antimicrobial Wound Gel|OTHER: Standard of Care
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: NONE|Primary Purpose: TREATMENT
Clinical trial: Effect of Motor Control Exercise Combined With Laser Or TENS on Pain, Range of Motion, and Functional Disability on Obese Patients With Low Back Pain
Status: COMPLETED
Conditions: Back Pain|Obesity|Motor Control Exercises|Laser Therapy
Interventions: OTHER: low-level laser therapy|OTHER: TENS|OTHER: motor control exercises
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (PARTICIPANT)|Primary Purpose: TREATMENT
Clinical trial: Effects of Visceral Manipulation in Women With Urinary Incontinence
Status: COMPLETED
Conditions: Urinary Incontinence
Interventions: OTHER: Pelvic Floor muscle training - PFMT|OTHER: Visceral Manual Therapy - VMT|OTHER: Manual Sham Therapy - MST
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: Canakinumab for the Treatment of Postprandial Hypoglycemia
Status: RECRUITING
Conditions: Postprandial Hypoglycemia
Interventions: DRUG: Canakinumab|DRUG: Placebo (0.9% NaCl)
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effect of Pirfenidone on Glomerular Filtration Rate and Albuminuria in Patients With Diabetic Nephropathy
Status: COMPLETED
Conditions: Diabetic Nephropathy|Albuminuria
Interventions: DRUG: Pirfenidone|DRUG: Placebo
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Glycemic and Insulinemic Impact of a Test Granola Versus a Control Granola
Status: COMPLETED
Conditions: Glycemic|Insulinemic|Subjective Hunger Responses
Interventions: OTHER: Test Granola|OTHER: Control Granola
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: CROSSOVER|Masking: DOUBLE (PARTICIPANT, INVESTIGATOR)|Primary Purpose: BASIC_SCIENCE
Clinical trial: Study of How Dulaglutide Compares to Placebo in Participants With Type 2 Diabetes Who Are Also on Sulfonylurea Therapy (AWARD-8)
Status: COMPLETED
Conditions: Type 2 Diabetes Mellitus
Interventions: DRUG: Placebo|DRUG: Dulaglutide|DRUG: Glimepiride
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, INVESTIGATOR)|Primary Purpose: TREATMENT
Clinical trial: Effectiveness in Dental Plaque Reduction of Mouthwashes Containing Fatty Acids Compounds (F.A.G.) or Stannous Fluoride
Status: COMPLETED
Conditions: Gingivitis|Gingival Diseases
Interventions: DRUG: Fatty Acids Compounds (F.A.G.) Mouthwash|DRUG: Stannous Fluoride (SF) Mouthwash
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: TRIPLE (PARTICIPANT, CARE_PROVIDER, OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT
Clinical trial: The Effect of Dry Needling Treatment Combined With Physical Therapy in Patients With Cervical Spondylosis
Status: COMPLETED
Conditions: Dry Needling|Cervical Spondylosis|Physical Therapy
Interventions: OTHER: Dry needling|OTHER: Physical therapy and rehabilitation
Study Type: INTERVENTIONAL
Study Design: Allocation: RANDOMIZED|Intervention Model: PARALLEL|Masking: SINGLE (OUTCOMES_ASSESSOR)|Primary Purpose: TREATMENT